ORF_ID e_value Gene_name EC_number CAZy COGs Description
KKGFHILH_00001 1.2e-210 S Bacterial protein of unknown function (DUF871)
KKGFHILH_00003 2.3e-43 ybhL S Belongs to the BI1 family
KKGFHILH_00004 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKGFHILH_00005 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKGFHILH_00006 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKGFHILH_00007 1.5e-203 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKGFHILH_00010 1.7e-195 ampC V Beta-lactamase
KKGFHILH_00011 4.9e-217 EGP Major facilitator Superfamily
KKGFHILH_00012 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
KKGFHILH_00013 1.1e-104 vanZ V VanZ like family
KKGFHILH_00014 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KKGFHILH_00015 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
KKGFHILH_00016 4.4e-129 K Transcriptional regulatory protein, C terminal
KKGFHILH_00017 7.7e-67 S SdpI/YhfL protein family
KKGFHILH_00018 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
KKGFHILH_00019 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
KKGFHILH_00020 2.5e-89 M Protein of unknown function (DUF3737)
KKGFHILH_00022 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
KKGFHILH_00023 1.2e-299 I Protein of unknown function (DUF2974)
KKGFHILH_00024 2.1e-194 pbpX1 V Beta-lactamase
KKGFHILH_00025 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KKGFHILH_00026 2.7e-216 aspC 2.6.1.1 E Aminotransferase
KKGFHILH_00027 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KKGFHILH_00028 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKGFHILH_00029 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KKGFHILH_00030 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KKGFHILH_00031 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KKGFHILH_00032 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KKGFHILH_00033 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KKGFHILH_00034 3.4e-175 yjeM E Amino Acid
KKGFHILH_00035 7.8e-39 yjeM E Amino Acid
KKGFHILH_00036 0.0 uvrA3 L excinuclease ABC, A subunit
KKGFHILH_00037 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KKGFHILH_00038 2.1e-114 3.6.1.27 I Acid phosphatase homologues
KKGFHILH_00039 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
KKGFHILH_00040 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKGFHILH_00041 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
KKGFHILH_00042 9.3e-204 pbpX1 V Beta-lactamase
KKGFHILH_00043 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KKGFHILH_00044 7.5e-95 S ECF-type riboflavin transporter, S component
KKGFHILH_00045 1.3e-229 S Putative peptidoglycan binding domain
KKGFHILH_00046 9e-83 K Acetyltransferase (GNAT) domain
KKGFHILH_00047 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKGFHILH_00048 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KKGFHILH_00050 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKGFHILH_00051 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
KKGFHILH_00052 1.3e-61 M Glycosyl hydrolases family 25
KKGFHILH_00053 2.6e-61 M Glycosyl hydrolases family 25
KKGFHILH_00054 0.0 L PLD-like domain
KKGFHILH_00055 4.8e-42 S SnoaL-like domain
KKGFHILH_00056 5.4e-53 hipB K sequence-specific DNA binding
KKGFHILH_00057 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KKGFHILH_00058 3.4e-27
KKGFHILH_00059 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
KKGFHILH_00060 5.7e-272 P Sodium:sulfate symporter transmembrane region
KKGFHILH_00061 1.7e-153 ydjP I Alpha/beta hydrolase family
KKGFHILH_00062 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KKGFHILH_00063 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
KKGFHILH_00064 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KKGFHILH_00065 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KKGFHILH_00066 9.3e-72 yeaL S Protein of unknown function (DUF441)
KKGFHILH_00067 3.5e-21
KKGFHILH_00068 3.6e-146 cbiQ P cobalt transport
KKGFHILH_00069 0.0 ykoD P ABC transporter, ATP-binding protein
KKGFHILH_00070 1.5e-95 S UPF0397 protein
KKGFHILH_00071 2.9e-66 S Domain of unknown function DUF1828
KKGFHILH_00072 5.5e-09
KKGFHILH_00073 1.5e-50
KKGFHILH_00074 2.6e-177 citR K Putative sugar-binding domain
KKGFHILH_00075 6.5e-249 yjjP S Putative threonine/serine exporter
KKGFHILH_00077 5.9e-37 M domain protein
KKGFHILH_00078 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KKGFHILH_00079 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
KKGFHILH_00080 8.5e-60
KKGFHILH_00081 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKGFHILH_00082 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KKGFHILH_00083 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KKGFHILH_00084 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KKGFHILH_00085 1.2e-222 patA 2.6.1.1 E Aminotransferase
KKGFHILH_00086 9.4e-46
KKGFHILH_00087 1.8e-38 D Alpha beta
KKGFHILH_00088 3.7e-122 D Alpha beta
KKGFHILH_00089 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKGFHILH_00090 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
KKGFHILH_00091 1.6e-85
KKGFHILH_00092 2.7e-74
KKGFHILH_00093 1.4e-140 hlyX S Transporter associated domain
KKGFHILH_00094 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KKGFHILH_00095 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
KKGFHILH_00096 0.0 clpE O Belongs to the ClpA ClpB family
KKGFHILH_00098 5.2e-104
KKGFHILH_00099 1.3e-159 degV S EDD domain protein, DegV family
KKGFHILH_00100 1.1e-66
KKGFHILH_00101 0.0 FbpA K Fibronectin-binding protein
KKGFHILH_00102 2.9e-86 V N-6 DNA Methylase
KKGFHILH_00103 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
KKGFHILH_00104 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKGFHILH_00105 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKGFHILH_00106 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KKGFHILH_00107 1.4e-115 mmuP E amino acid
KKGFHILH_00108 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
KKGFHILH_00109 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
KKGFHILH_00110 1.7e-284 E Amino acid permease
KKGFHILH_00111 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KKGFHILH_00112 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
KKGFHILH_00113 2e-234 mepA V MATE efflux family protein
KKGFHILH_00114 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
KKGFHILH_00115 1.8e-58 S Putative adhesin
KKGFHILH_00116 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KKGFHILH_00117 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
KKGFHILH_00118 1.1e-83 dps P Belongs to the Dps family
KKGFHILH_00119 2e-178 MA20_14895 S Conserved hypothetical protein 698
KKGFHILH_00121 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KKGFHILH_00122 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KKGFHILH_00123 9e-98
KKGFHILH_00124 4.9e-108 K LysR substrate binding domain
KKGFHILH_00125 1e-20
KKGFHILH_00126 2.3e-215 S Sterol carrier protein domain
KKGFHILH_00127 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KKGFHILH_00128 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
KKGFHILH_00129 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KKGFHILH_00130 5.7e-233 arcA 3.5.3.6 E Arginine
KKGFHILH_00131 9e-137 lysR5 K LysR substrate binding domain
KKGFHILH_00132 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KKGFHILH_00133 1e-48 S Metal binding domain of Ada
KKGFHILH_00134 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KKGFHILH_00135 1e-149 D Alpha beta
KKGFHILH_00136 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKGFHILH_00137 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKGFHILH_00138 8.3e-143 licT K CAT RNA binding domain
KKGFHILH_00139 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KKGFHILH_00140 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKGFHILH_00141 1.6e-118
KKGFHILH_00142 1.8e-75 K Penicillinase repressor
KKGFHILH_00143 1.4e-147 S hydrolase
KKGFHILH_00144 1.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKGFHILH_00145 2e-172 ybbR S YbbR-like protein
KKGFHILH_00146 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KKGFHILH_00147 7.3e-208 potD P ABC transporter
KKGFHILH_00148 4.8e-127 potC P ABC transporter permease
KKGFHILH_00149 1.3e-129 potB P ABC transporter permease
KKGFHILH_00150 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KKGFHILH_00151 2e-163 murB 1.3.1.98 M Cell wall formation
KKGFHILH_00152 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
KKGFHILH_00153 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KKGFHILH_00154 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KKGFHILH_00155 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKGFHILH_00156 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
KKGFHILH_00157 1.2e-94
KKGFHILH_00158 1.4e-94
KKGFHILH_00159 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
KKGFHILH_00160 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KKGFHILH_00161 1.9e-261 frdC 1.3.5.4 C FAD binding domain
KKGFHILH_00162 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KKGFHILH_00163 3.4e-73 metI P ABC transporter permease
KKGFHILH_00164 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKGFHILH_00165 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
KKGFHILH_00166 2.4e-175 F DNA/RNA non-specific endonuclease
KKGFHILH_00167 0.0 aha1 P E1-E2 ATPase
KKGFHILH_00168 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KKGFHILH_00169 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKGFHILH_00170 1.2e-250 yifK E Amino acid permease
KKGFHILH_00171 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00172 3.9e-128 S CAAX protease self-immunity
KKGFHILH_00173 8e-224 S SLAP domain
KKGFHILH_00174 1.2e-54 S Abi-like protein
KKGFHILH_00175 1.5e-72 S Aminoacyl-tRNA editing domain
KKGFHILH_00176 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKGFHILH_00177 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KKGFHILH_00178 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKGFHILH_00179 8.8e-62 yodB K Transcriptional regulator, HxlR family
KKGFHILH_00181 9.6e-110 papP P ABC transporter, permease protein
KKGFHILH_00182 2e-110 P ABC transporter permease
KKGFHILH_00183 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KKGFHILH_00184 3e-53 cjaA ET ABC transporter substrate-binding protein
KKGFHILH_00185 8.1e-91 cjaA ET ABC transporter substrate-binding protein
KKGFHILH_00186 2.9e-277 V ABC transporter transmembrane region
KKGFHILH_00187 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KKGFHILH_00188 3.1e-130 T Transcriptional regulatory protein, C terminal
KKGFHILH_00189 5.2e-187 T GHKL domain
KKGFHILH_00190 3.4e-76 S Peptidase propeptide and YPEB domain
KKGFHILH_00191 2.5e-72 S Peptidase propeptide and YPEB domain
KKGFHILH_00192 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KKGFHILH_00193 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
KKGFHILH_00194 7e-68 V ABC transporter transmembrane region
KKGFHILH_00195 9e-161 V ABC transporter transmembrane region
KKGFHILH_00196 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KKGFHILH_00197 2.3e-23 S Protein of unknown function (DUF2929)
KKGFHILH_00198 0.0 dnaE 2.7.7.7 L DNA polymerase
KKGFHILH_00199 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KKGFHILH_00200 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KKGFHILH_00201 1e-167 cvfB S S1 domain
KKGFHILH_00202 2.9e-165 xerD D recombinase XerD
KKGFHILH_00203 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKGFHILH_00204 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KKGFHILH_00205 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKGFHILH_00206 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKGFHILH_00207 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KKGFHILH_00208 2.7e-18 M Lysin motif
KKGFHILH_00209 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KKGFHILH_00210 1.4e-24 rpsA 1.17.7.4 J Ribosomal protein S1
KKGFHILH_00211 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KKGFHILH_00212 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KKGFHILH_00213 3.9e-229 S Tetratricopeptide repeat protein
KKGFHILH_00214 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKGFHILH_00215 2e-75 S cog cog0433
KKGFHILH_00216 1.9e-110 F DNA/RNA non-specific endonuclease
KKGFHILH_00217 2.7e-34 S YSIRK type signal peptide
KKGFHILH_00219 5.5e-53
KKGFHILH_00220 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KKGFHILH_00221 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKGFHILH_00222 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKGFHILH_00223 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKGFHILH_00224 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
KKGFHILH_00225 5.3e-26
KKGFHILH_00226 8.5e-41 ptsH G phosphocarrier protein HPR
KKGFHILH_00227 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KKGFHILH_00228 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KKGFHILH_00229 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KKGFHILH_00230 1.4e-158 coiA 3.6.4.12 S Competence protein
KKGFHILH_00231 4.6e-114 yjbH Q Thioredoxin
KKGFHILH_00232 6.8e-110 yjbK S CYTH
KKGFHILH_00233 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
KKGFHILH_00234 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKGFHILH_00235 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKGFHILH_00236 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KKGFHILH_00237 4.2e-92 S SNARE associated Golgi protein
KKGFHILH_00238 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KKGFHILH_00239 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KKGFHILH_00240 2.6e-214 yubA S AI-2E family transporter
KKGFHILH_00241 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KKGFHILH_00242 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
KKGFHILH_00243 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KKGFHILH_00244 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KKGFHILH_00245 1.9e-236 S Peptidase M16
KKGFHILH_00246 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
KKGFHILH_00247 5.2e-97 ymfM S Helix-turn-helix domain
KKGFHILH_00248 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKGFHILH_00249 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKGFHILH_00250 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
KKGFHILH_00251 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
KKGFHILH_00252 5.1e-119 yvyE 3.4.13.9 S YigZ family
KKGFHILH_00253 4.7e-246 comFA L Helicase C-terminal domain protein
KKGFHILH_00254 9.4e-132 comFC S Competence protein
KKGFHILH_00255 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KKGFHILH_00256 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KKGFHILH_00257 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKGFHILH_00258 5.1e-17
KKGFHILH_00259 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KKGFHILH_00260 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKGFHILH_00261 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KKGFHILH_00262 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KKGFHILH_00263 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KKGFHILH_00264 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KKGFHILH_00265 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KKGFHILH_00266 4.1e-90 S Short repeat of unknown function (DUF308)
KKGFHILH_00267 6.2e-165 rapZ S Displays ATPase and GTPase activities
KKGFHILH_00268 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KKGFHILH_00269 2.1e-171 whiA K May be required for sporulation
KKGFHILH_00270 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KKGFHILH_00271 0.0 S SH3-like domain
KKGFHILH_00272 3.9e-51 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00273 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00274 8.4e-56 S Domain of unknown function (DUF4767)
KKGFHILH_00275 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKGFHILH_00276 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
KKGFHILH_00277 3.2e-101 3.6.1.27 I Acid phosphatase homologues
KKGFHILH_00278 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KKGFHILH_00279 4.8e-34 S reductase
KKGFHILH_00280 4.4e-39 S reductase
KKGFHILH_00281 2.7e-32 S reductase
KKGFHILH_00282 1.3e-148 yxeH S hydrolase
KKGFHILH_00283 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKGFHILH_00284 1.1e-243 yfnA E Amino Acid
KKGFHILH_00285 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
KKGFHILH_00286 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KKGFHILH_00287 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKGFHILH_00288 2.2e-292 I Acyltransferase
KKGFHILH_00289 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KKGFHILH_00290 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KKGFHILH_00291 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
KKGFHILH_00292 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KKGFHILH_00293 1.6e-15 L hmm pf00665
KKGFHILH_00294 2.9e-15 M LysM domain protein
KKGFHILH_00295 3.8e-48 M LysM domain protein
KKGFHILH_00296 1.4e-86 C Aldo keto reductase
KKGFHILH_00297 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
KKGFHILH_00298 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KKGFHILH_00299 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KKGFHILH_00300 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
KKGFHILH_00301 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KKGFHILH_00302 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKGFHILH_00303 5.8e-152 dprA LU DNA protecting protein DprA
KKGFHILH_00304 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKGFHILH_00305 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KKGFHILH_00306 1.9e-94 yjcE P Sodium proton antiporter
KKGFHILH_00307 1.5e-40 yjcE P Sodium proton antiporter
KKGFHILH_00308 1.1e-66 yjcE P NhaP-type Na H and K H
KKGFHILH_00309 7.1e-36 yozE S Belongs to the UPF0346 family
KKGFHILH_00310 2e-144 DegV S Uncharacterised protein, DegV family COG1307
KKGFHILH_00311 1.2e-107 hlyIII S protein, hemolysin III
KKGFHILH_00312 3.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KKGFHILH_00313 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKGFHILH_00314 4.3e-86 3.4.21.96 S SLAP domain
KKGFHILH_00315 8.4e-128 yagE E Amino acid permease
KKGFHILH_00316 9.7e-65 yagE E amino acid
KKGFHILH_00317 2.2e-113 S SLAP domain
KKGFHILH_00318 2.9e-53 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KKGFHILH_00319 5.7e-46 S An automated process has identified a potential problem with this gene model
KKGFHILH_00320 3e-137 S Protein of unknown function (DUF3100)
KKGFHILH_00321 4e-245 3.5.1.47 S Peptidase dimerisation domain
KKGFHILH_00322 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
KKGFHILH_00323 0.0 oppA E ABC transporter
KKGFHILH_00324 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
KKGFHILH_00325 0.0 mco Q Multicopper oxidase
KKGFHILH_00326 1.9e-25
KKGFHILH_00327 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
KKGFHILH_00328 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
KKGFHILH_00329 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KKGFHILH_00330 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKGFHILH_00331 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKGFHILH_00333 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKGFHILH_00334 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KKGFHILH_00335 1.5e-197 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KKGFHILH_00336 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KKGFHILH_00337 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KKGFHILH_00338 1.7e-29 secG U Preprotein translocase
KKGFHILH_00339 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KKGFHILH_00340 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KKGFHILH_00341 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
KKGFHILH_00342 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KKGFHILH_00349 0.0 V FtsX-like permease family
KKGFHILH_00350 4.1e-133 cysA V ABC transporter, ATP-binding protein
KKGFHILH_00351 3.4e-23
KKGFHILH_00352 2.5e-288 pipD E Dipeptidase
KKGFHILH_00353 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KKGFHILH_00354 0.0 smc D Required for chromosome condensation and partitioning
KKGFHILH_00355 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KKGFHILH_00356 2.1e-308 oppA E ABC transporter substrate-binding protein
KKGFHILH_00357 3.1e-240 oppA E ABC transporter substrate-binding protein
KKGFHILH_00358 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KKGFHILH_00359 3.3e-61 3.6.1.55 F NUDIX domain
KKGFHILH_00360 1e-79 S AAA domain
KKGFHILH_00361 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
KKGFHILH_00362 1.3e-277 arlS 2.7.13.3 T Histidine kinase
KKGFHILH_00363 1.2e-126 K response regulator
KKGFHILH_00364 4.7e-97 yceD S Uncharacterized ACR, COG1399
KKGFHILH_00365 1.7e-215 ylbM S Belongs to the UPF0348 family
KKGFHILH_00366 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KKGFHILH_00367 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KKGFHILH_00368 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKGFHILH_00369 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
KKGFHILH_00370 4.2e-84 yqeG S HAD phosphatase, family IIIA
KKGFHILH_00371 9.2e-201 tnpB L Putative transposase DNA-binding domain
KKGFHILH_00372 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KKGFHILH_00373 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKGFHILH_00374 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KKGFHILH_00375 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKGFHILH_00376 4e-98 rihB 3.2.2.1 F Nucleoside
KKGFHILH_00377 2.7e-258 yfnA E amino acid
KKGFHILH_00378 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KKGFHILH_00379 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KKGFHILH_00380 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KKGFHILH_00381 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KKGFHILH_00382 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KKGFHILH_00383 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KKGFHILH_00384 4.6e-213 S SLAP domain
KKGFHILH_00385 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
KKGFHILH_00386 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
KKGFHILH_00387 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKGFHILH_00388 3e-38 ynzC S UPF0291 protein
KKGFHILH_00389 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
KKGFHILH_00390 0.0 mdlA V ABC transporter
KKGFHILH_00391 0.0 mdlB V ABC transporter
KKGFHILH_00392 0.0 pepO 3.4.24.71 O Peptidase family M13
KKGFHILH_00393 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KKGFHILH_00394 2.9e-116 plsC 2.3.1.51 I Acyltransferase
KKGFHILH_00395 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
KKGFHILH_00396 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KKGFHILH_00397 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KKGFHILH_00398 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KKGFHILH_00399 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KKGFHILH_00400 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKGFHILH_00401 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
KKGFHILH_00402 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KKGFHILH_00403 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KKGFHILH_00404 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKGFHILH_00405 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
KKGFHILH_00406 1.4e-196 nusA K Participates in both transcription termination and antitermination
KKGFHILH_00407 1.5e-43 ylxR K Protein of unknown function (DUF448)
KKGFHILH_00408 3.2e-47 rplGA J ribosomal protein
KKGFHILH_00409 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKGFHILH_00410 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKGFHILH_00411 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKGFHILH_00412 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KKGFHILH_00413 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KKGFHILH_00414 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKGFHILH_00415 0.0 dnaK O Heat shock 70 kDa protein
KKGFHILH_00416 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KKGFHILH_00417 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KKGFHILH_00418 1.5e-102 srtA 3.4.22.70 M sortase family
KKGFHILH_00419 4.7e-26 K FCD
KKGFHILH_00420 1.6e-60 clcA P chloride
KKGFHILH_00421 8.8e-41 clcA P chloride
KKGFHILH_00422 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
KKGFHILH_00423 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KKGFHILH_00424 6.4e-128 K UTRA domain
KKGFHILH_00425 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKGFHILH_00426 2e-85 alkD L DNA alkylation repair enzyme
KKGFHILH_00427 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
KKGFHILH_00428 1.2e-80
KKGFHILH_00429 3.6e-39 C FMN_bind
KKGFHILH_00430 1.2e-188 K Periplasmic binding protein-like domain
KKGFHILH_00431 2e-106 K Transcriptional regulator, AbiEi antitoxin
KKGFHILH_00432 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
KKGFHILH_00433 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKGFHILH_00434 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KKGFHILH_00435 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KKGFHILH_00436 3.2e-165 lacR K Transcriptional regulator
KKGFHILH_00437 0.0 lacS G Transporter
KKGFHILH_00438 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KKGFHILH_00439 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKGFHILH_00440 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KKGFHILH_00441 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KKGFHILH_00442 5.5e-36
KKGFHILH_00443 6.4e-71 scrR K Periplasmic binding protein domain
KKGFHILH_00444 2.7e-94 mreD
KKGFHILH_00445 2e-147 mreC M Involved in formation and maintenance of cell shape
KKGFHILH_00446 2.4e-176 mreB D cell shape determining protein MreB
KKGFHILH_00447 2.3e-108 radC L DNA repair protein
KKGFHILH_00448 5.7e-126 S Haloacid dehalogenase-like hydrolase
KKGFHILH_00449 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KKGFHILH_00450 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KKGFHILH_00451 2.5e-52
KKGFHILH_00452 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
KKGFHILH_00453 0.0 3.6.3.8 P P-type ATPase
KKGFHILH_00455 6.5e-44
KKGFHILH_00456 1.5e-94 S Protein of unknown function (DUF3990)
KKGFHILH_00457 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KKGFHILH_00458 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
KKGFHILH_00459 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KKGFHILH_00460 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKGFHILH_00461 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KKGFHILH_00462 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKGFHILH_00463 4.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
KKGFHILH_00464 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KKGFHILH_00465 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KKGFHILH_00466 1.3e-84 yueI S Protein of unknown function (DUF1694)
KKGFHILH_00467 6.3e-238 rarA L recombination factor protein RarA
KKGFHILH_00468 8.4e-39
KKGFHILH_00469 1.8e-78 usp6 T universal stress protein
KKGFHILH_00470 4.7e-216 rodA D Belongs to the SEDS family
KKGFHILH_00471 3.3e-33 S Protein of unknown function (DUF2969)
KKGFHILH_00472 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KKGFHILH_00473 1.2e-177 mbl D Cell shape determining protein MreB Mrl
KKGFHILH_00474 2e-30 ywzB S Protein of unknown function (DUF1146)
KKGFHILH_00475 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KKGFHILH_00476 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KKGFHILH_00477 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KKGFHILH_00478 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKGFHILH_00479 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKGFHILH_00480 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKGFHILH_00481 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKGFHILH_00482 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KKGFHILH_00483 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KKGFHILH_00484 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KKGFHILH_00485 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KKGFHILH_00486 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KKGFHILH_00487 1.7e-113 tdk 2.7.1.21 F thymidine kinase
KKGFHILH_00488 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KKGFHILH_00490 5e-29
KKGFHILH_00491 5.7e-171 M Glycosyl hydrolases family 25
KKGFHILH_00494 1.3e-122 S haloacid dehalogenase-like hydrolase
KKGFHILH_00495 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00496 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00497 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
KKGFHILH_00498 8.5e-178 I Carboxylesterase family
KKGFHILH_00500 1e-205 M Glycosyl hydrolases family 25
KKGFHILH_00501 1.2e-155 cinI S Serine hydrolase (FSH1)
KKGFHILH_00502 4.3e-298 S Predicted membrane protein (DUF2207)
KKGFHILH_00503 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KKGFHILH_00505 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
KKGFHILH_00506 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKGFHILH_00507 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KKGFHILH_00508 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KKGFHILH_00509 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KKGFHILH_00510 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKGFHILH_00511 3.4e-71 yqhY S Asp23 family, cell envelope-related function
KKGFHILH_00512 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKGFHILH_00513 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKGFHILH_00514 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKGFHILH_00515 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKGFHILH_00516 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKGFHILH_00517 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KKGFHILH_00518 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
KKGFHILH_00519 1.1e-77 6.3.3.2 S ASCH
KKGFHILH_00520 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KKGFHILH_00521 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KKGFHILH_00522 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKGFHILH_00523 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KKGFHILH_00524 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KKGFHILH_00525 1.1e-138 stp 3.1.3.16 T phosphatase
KKGFHILH_00526 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KKGFHILH_00527 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KKGFHILH_00528 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KKGFHILH_00529 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
KKGFHILH_00530 1.4e-30
KKGFHILH_00531 9.9e-118 L Belongs to the 'phage' integrase family
KKGFHILH_00533 2.2e-15 E Pfam:DUF955
KKGFHILH_00535 4.7e-18 K Helix-turn-helix XRE-family like proteins
KKGFHILH_00536 4.4e-79 S Phage antirepressor protein KilAC domain
KKGFHILH_00537 3.5e-46
KKGFHILH_00543 1.6e-70 S AAA domain
KKGFHILH_00545 4.7e-148 res L Helicase C-terminal domain protein
KKGFHILH_00546 1.7e-30 S Protein of unknown function (DUF669)
KKGFHILH_00547 2.7e-268 S Phage plasmid primase, P4
KKGFHILH_00558 3.3e-37 S VRR_NUC
KKGFHILH_00560 9.8e-12
KKGFHILH_00561 3.1e-14 arpU S Phage transcriptional regulator, ArpU family
KKGFHILH_00563 3.5e-49 L HNH nucleases
KKGFHILH_00564 1.6e-55 L Phage terminase, small subunit
KKGFHILH_00565 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
KKGFHILH_00566 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
KKGFHILH_00567 2.8e-210 S Phage Terminase
KKGFHILH_00568 3.6e-140 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KKGFHILH_00569 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
KKGFHILH_00570 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
KKGFHILH_00571 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
KKGFHILH_00572 1.9e-22 K Putative DNA-binding domain
KKGFHILH_00573 7.6e-239 pyrP F Permease
KKGFHILH_00574 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKGFHILH_00575 9.2e-262 emrY EGP Major facilitator Superfamily
KKGFHILH_00576 1.9e-138 2.4.2.3 F Phosphorylase superfamily
KKGFHILH_00577 9e-144 2.4.2.3 F Phosphorylase superfamily
KKGFHILH_00578 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KKGFHILH_00579 8.1e-126 S PAS domain
KKGFHILH_00580 1.6e-11
KKGFHILH_00581 2.7e-57
KKGFHILH_00582 6.6e-56
KKGFHILH_00583 4e-08
KKGFHILH_00584 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKGFHILH_00585 3.3e-275 yjeM E Amino Acid
KKGFHILH_00586 5.8e-83 S Fic/DOC family
KKGFHILH_00587 2.7e-285
KKGFHILH_00588 3.2e-77
KKGFHILH_00589 2.3e-87 S Protein of unknown function (DUF805)
KKGFHILH_00590 5.6e-68 O OsmC-like protein
KKGFHILH_00591 9.4e-209 EGP Major facilitator Superfamily
KKGFHILH_00592 2.5e-215 sptS 2.7.13.3 T Histidine kinase
KKGFHILH_00593 2.2e-85 S PFAM Archaeal ATPase
KKGFHILH_00594 5.7e-84 S PFAM Archaeal ATPase
KKGFHILH_00595 7.7e-26
KKGFHILH_00596 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
KKGFHILH_00597 1.3e-116 S Peptidase family M23
KKGFHILH_00598 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKGFHILH_00600 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKGFHILH_00601 9.4e-118
KKGFHILH_00602 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KKGFHILH_00603 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KKGFHILH_00604 2.6e-280 thrC 4.2.3.1 E Threonine synthase
KKGFHILH_00605 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KKGFHILH_00606 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
KKGFHILH_00607 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
KKGFHILH_00608 2e-157 S reductase
KKGFHILH_00609 9.3e-35
KKGFHILH_00611 6.4e-54 S Protein of unknown function (DUF3397)
KKGFHILH_00612 6.3e-78 mraZ K Belongs to the MraZ family
KKGFHILH_00613 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KKGFHILH_00614 1.8e-54 ftsL D Cell division protein FtsL
KKGFHILH_00615 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KKGFHILH_00616 3.3e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKGFHILH_00617 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKGFHILH_00618 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKGFHILH_00619 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KKGFHILH_00620 6.7e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KKGFHILH_00621 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KKGFHILH_00622 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KKGFHILH_00623 1.7e-45 yggT S YGGT family
KKGFHILH_00624 5.7e-149 ylmH S S4 domain protein
KKGFHILH_00625 2.8e-74 gpsB D DivIVA domain protein
KKGFHILH_00626 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKGFHILH_00627 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
KKGFHILH_00628 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KKGFHILH_00629 6.7e-37
KKGFHILH_00630 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KKGFHILH_00631 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
KKGFHILH_00632 5.4e-56 XK27_04120 S Putative amino acid metabolism
KKGFHILH_00633 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KKGFHILH_00634 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KKGFHILH_00635 2.4e-105 S Repeat protein
KKGFHILH_00636 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KKGFHILH_00637 1.6e-294 L Nuclease-related domain
KKGFHILH_00638 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KKGFHILH_00639 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KKGFHILH_00640 4e-57 asp S Asp23 family, cell envelope-related function
KKGFHILH_00641 7.6e-305 yloV S DAK2 domain fusion protein YloV
KKGFHILH_00642 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KKGFHILH_00643 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KKGFHILH_00644 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKGFHILH_00645 1.1e-192 oppD P Belongs to the ABC transporter superfamily
KKGFHILH_00646 1.5e-170 oppF P Belongs to the ABC transporter superfamily
KKGFHILH_00647 2.6e-172 oppB P ABC transporter permease
KKGFHILH_00648 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
KKGFHILH_00649 9.7e-46 oppA E ABC transporter substrate-binding protein
KKGFHILH_00650 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
KKGFHILH_00651 3.4e-79
KKGFHILH_00652 1e-242 cpdA S Calcineurin-like phosphoesterase
KKGFHILH_00653 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KKGFHILH_00654 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KKGFHILH_00655 1e-107 ypsA S Belongs to the UPF0398 family
KKGFHILH_00656 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KKGFHILH_00657 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KKGFHILH_00658 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KKGFHILH_00659 1.3e-114 dnaD L DnaD domain protein
KKGFHILH_00660 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KKGFHILH_00661 2.4e-89 ypmB S Protein conserved in bacteria
KKGFHILH_00662 3e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KKGFHILH_00663 9.2e-14
KKGFHILH_00664 1.6e-121 M Glycosyl hydrolases family 25
KKGFHILH_00665 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KKGFHILH_00666 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
KKGFHILH_00667 5.6e-179 S PFAM Archaeal ATPase
KKGFHILH_00668 2.4e-73 S cog cog1373
KKGFHILH_00669 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKGFHILH_00670 3.5e-70 S Domain of unknown function (DUF3284)
KKGFHILH_00671 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKGFHILH_00672 5.3e-130 gmuR K UTRA
KKGFHILH_00673 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KKGFHILH_00674 3.2e-181 ccpA K catabolite control protein A
KKGFHILH_00675 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKGFHILH_00676 4.3e-55
KKGFHILH_00677 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KKGFHILH_00678 2.1e-92 yutD S Protein of unknown function (DUF1027)
KKGFHILH_00679 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KKGFHILH_00680 3.7e-100 S Protein of unknown function (DUF1461)
KKGFHILH_00681 6.8e-116 dedA S SNARE-like domain protein
KKGFHILH_00682 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KKGFHILH_00683 1.3e-36
KKGFHILH_00684 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KKGFHILH_00685 3.7e-146 ykuT M mechanosensitive ion channel
KKGFHILH_00686 6.9e-100 V ATPases associated with a variety of cellular activities
KKGFHILH_00687 1.7e-139
KKGFHILH_00688 5.4e-113
KKGFHILH_00689 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKGFHILH_00690 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKGFHILH_00691 7.2e-56 yheA S Belongs to the UPF0342 family
KKGFHILH_00692 1e-226 yhaO L Ser Thr phosphatase family protein
KKGFHILH_00693 0.0 L AAA domain
KKGFHILH_00694 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KKGFHILH_00695 2.9e-23
KKGFHILH_00696 2.4e-51 S Domain of unknown function DUF1829
KKGFHILH_00697 1.1e-265
KKGFHILH_00698 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
KKGFHILH_00699 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KKGFHILH_00700 3.9e-25
KKGFHILH_00701 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
KKGFHILH_00702 5.7e-135 ecsA V ABC transporter, ATP-binding protein
KKGFHILH_00703 6.5e-221 ecsB U ABC transporter
KKGFHILH_00704 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KKGFHILH_00706 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKGFHILH_00707 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKGFHILH_00708 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KKGFHILH_00709 6.9e-218 mepA V MATE efflux family protein
KKGFHILH_00710 1.8e-176 S SLAP domain
KKGFHILH_00711 4.4e-283 M Peptidase family M1 domain
KKGFHILH_00712 4.5e-188 S Bacteriocin helveticin-J
KKGFHILH_00713 8e-51 L RelB antitoxin
KKGFHILH_00714 7.4e-105 qmcA O prohibitin homologues
KKGFHILH_00715 3.5e-25 qmcA O prohibitin homologues
KKGFHILH_00716 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKGFHILH_00717 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KKGFHILH_00718 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKGFHILH_00719 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKGFHILH_00720 5.1e-251 dnaB L Replication initiation and membrane attachment
KKGFHILH_00721 1.3e-168 dnaI L Primosomal protein DnaI
KKGFHILH_00722 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKGFHILH_00723 4.3e-75
KKGFHILH_00724 4e-60 L Resolvase, N terminal domain
KKGFHILH_00725 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KKGFHILH_00726 3.2e-103 L An automated process has identified a potential problem with this gene model
KKGFHILH_00727 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
KKGFHILH_00728 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
KKGFHILH_00729 3.6e-241 3.6.3.6 P Cation transporter/ATPase, N-terminus
KKGFHILH_00730 1.9e-19
KKGFHILH_00731 2.2e-142 S Belongs to the UPF0246 family
KKGFHILH_00732 4.1e-141 aroD S Alpha/beta hydrolase family
KKGFHILH_00733 3.5e-111 G phosphoglycerate mutase
KKGFHILH_00734 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
KKGFHILH_00735 3.3e-176 hrtB V ABC transporter permease
KKGFHILH_00736 2e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KKGFHILH_00737 1.3e-273 pipD E Dipeptidase
KKGFHILH_00738 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KKGFHILH_00739 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KKGFHILH_00740 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KKGFHILH_00741 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKGFHILH_00742 2.2e-120 lsa S ABC transporter
KKGFHILH_00743 6e-46 L An automated process has identified a potential problem with this gene model
KKGFHILH_00744 2.8e-48 S Peptidase propeptide and YPEB domain
KKGFHILH_00745 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KKGFHILH_00746 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KKGFHILH_00747 1.3e-12 L TIGRFAM transposase, IS605 OrfB family
KKGFHILH_00748 1.2e-11 S Transposase C of IS166 homeodomain
KKGFHILH_00749 1.4e-59 XK27_01125 L IS66 Orf2 like protein
KKGFHILH_00750 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
KKGFHILH_00751 2.8e-182 K Transcriptional regulator
KKGFHILH_00752 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKGFHILH_00753 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKGFHILH_00754 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KKGFHILH_00755 0.0 snf 2.7.11.1 KL domain protein
KKGFHILH_00756 2e-35
KKGFHILH_00758 3.8e-104 pncA Q Isochorismatase family
KKGFHILH_00759 4.9e-118
KKGFHILH_00762 3.6e-63
KKGFHILH_00763 1.4e-34
KKGFHILH_00764 2.1e-47
KKGFHILH_00766 5e-07 K Helix-turn-helix XRE-family like proteins
KKGFHILH_00767 7.2e-10
KKGFHILH_00772 1.1e-90 S AntA/AntB antirepressor
KKGFHILH_00774 2e-20 cro K Helix-turn-helix XRE-family like proteins
KKGFHILH_00775 2.8e-13 K Helix-turn-helix XRE-family like proteins
KKGFHILH_00777 3e-59
KKGFHILH_00778 6e-14
KKGFHILH_00782 2.5e-13
KKGFHILH_00783 1.6e-147 sip L Belongs to the 'phage' integrase family
KKGFHILH_00784 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KKGFHILH_00785 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KKGFHILH_00786 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KKGFHILH_00787 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KKGFHILH_00788 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KKGFHILH_00789 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KKGFHILH_00790 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KKGFHILH_00791 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
KKGFHILH_00792 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KKGFHILH_00793 9.7e-169
KKGFHILH_00794 7.5e-143
KKGFHILH_00795 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KKGFHILH_00796 1.4e-26
KKGFHILH_00797 6.7e-145
KKGFHILH_00798 5.1e-137
KKGFHILH_00799 4.5e-141
KKGFHILH_00800 9.6e-124 skfE V ATPases associated with a variety of cellular activities
KKGFHILH_00801 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
KKGFHILH_00802 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKGFHILH_00803 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KKGFHILH_00804 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KKGFHILH_00805 4.8e-81 mutT 3.6.1.55 F NUDIX domain
KKGFHILH_00806 1.4e-127 S Peptidase family M23
KKGFHILH_00807 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KKGFHILH_00808 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KKGFHILH_00809 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KKGFHILH_00810 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KKGFHILH_00811 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
KKGFHILH_00812 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKGFHILH_00813 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKGFHILH_00814 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
KKGFHILH_00815 3.5e-71 yqeY S YqeY-like protein
KKGFHILH_00816 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KKGFHILH_00817 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KKGFHILH_00818 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
KKGFHILH_00819 2.5e-197 M Phage tail tape measure protein TP901
KKGFHILH_00820 1.1e-11
KKGFHILH_00821 1.3e-11
KKGFHILH_00822 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
KKGFHILH_00823 1.6e-27
KKGFHILH_00824 2.7e-10
KKGFHILH_00825 7.7e-42
KKGFHILH_00826 1.6e-27 S Protein of unknown function (DUF4054)
KKGFHILH_00827 2.9e-36 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
KKGFHILH_00828 1e-22
KKGFHILH_00829 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2213)
KKGFHILH_00830 4.8e-20 S Lysin motif
KKGFHILH_00831 1.3e-55 S Phage Mu protein F like protein
KKGFHILH_00832 3.3e-91 S Protein of unknown function (DUF1073)
KKGFHILH_00833 9.6e-187 S Terminase-like family
KKGFHILH_00836 1.1e-20 S N-methyltransferase activity
KKGFHILH_00842 3.4e-09
KKGFHILH_00843 5.3e-36 S VRR_NUC
KKGFHILH_00845 2.2e-67 S ORF6C domain
KKGFHILH_00850 2.7e-33 Q DNA (cytosine-5-)-methyltransferase activity
KKGFHILH_00856 1.5e-21 radC L DNA repair protein
KKGFHILH_00857 4e-65 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KKGFHILH_00858 1.6e-31 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KKGFHILH_00860 2.7e-31 K Helix-turn-helix domain
KKGFHILH_00861 1.6e-44 S ERF superfamily
KKGFHILH_00862 2.2e-53 S Protein of unknown function (DUF1351)
KKGFHILH_00866 3.2e-10
KKGFHILH_00869 6.6e-11 K Helix-turn-helix XRE-family like proteins
KKGFHILH_00870 4.8e-17 S protein disulfide oxidoreductase activity
KKGFHILH_00873 1.4e-95 sip L Belongs to the 'phage' integrase family
KKGFHILH_00874 5.1e-12 S haloacid dehalogenase-like hydrolase
KKGFHILH_00875 7e-50
KKGFHILH_00876 1.9e-37
KKGFHILH_00877 1.2e-63 S Alpha beta hydrolase
KKGFHILH_00878 3.7e-19 S Alpha beta hydrolase
KKGFHILH_00879 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KKGFHILH_00880 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KKGFHILH_00881 7.1e-46
KKGFHILH_00882 3.1e-148 glcU U sugar transport
KKGFHILH_00883 3.7e-250 lctP C L-lactate permease
KKGFHILH_00884 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KKGFHILH_00885 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKGFHILH_00886 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KKGFHILH_00887 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KKGFHILH_00888 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKGFHILH_00889 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KKGFHILH_00890 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KKGFHILH_00891 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKGFHILH_00892 1.5e-102 GM NmrA-like family
KKGFHILH_00893 4.2e-63 lmrB EGP Major facilitator Superfamily
KKGFHILH_00894 2.9e-122 rbtT P Major Facilitator Superfamily
KKGFHILH_00895 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
KKGFHILH_00896 2.5e-86 K GNAT family
KKGFHILH_00897 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KKGFHILH_00899 4.3e-36
KKGFHILH_00900 6.2e-288 P ABC transporter
KKGFHILH_00901 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
KKGFHILH_00902 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKGFHILH_00903 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKGFHILH_00904 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KKGFHILH_00905 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KKGFHILH_00906 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KKGFHILH_00907 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKGFHILH_00908 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KKGFHILH_00909 2.3e-56 G Xylose isomerase domain protein TIM barrel
KKGFHILH_00910 8.4e-90 nanK GK ROK family
KKGFHILH_00911 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KKGFHILH_00912 3.7e-66 K Helix-turn-helix domain, rpiR family
KKGFHILH_00913 7.1e-263 E ABC transporter, substratebinding protein
KKGFHILH_00914 9.1e-10 K peptidyl-tyrosine sulfation
KKGFHILH_00916 4.5e-131 S interspecies interaction between organisms
KKGFHILH_00917 1.9e-11
KKGFHILH_00920 1.9e-21
KKGFHILH_00921 6e-148
KKGFHILH_00922 6.7e-170
KKGFHILH_00923 2e-263 glnA 6.3.1.2 E glutamine synthetase
KKGFHILH_00924 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
KKGFHILH_00925 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKGFHILH_00926 1.5e-65 yqhL P Rhodanese-like protein
KKGFHILH_00927 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KKGFHILH_00928 4e-119 gluP 3.4.21.105 S Rhomboid family
KKGFHILH_00929 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKGFHILH_00930 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KKGFHILH_00931 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KKGFHILH_00932 0.0 S membrane
KKGFHILH_00933 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KKGFHILH_00934 1.3e-38 S RelB antitoxin
KKGFHILH_00935 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KKGFHILH_00936 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KKGFHILH_00937 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
KKGFHILH_00938 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKGFHILH_00939 8.7e-159 isdE P Periplasmic binding protein
KKGFHILH_00940 6.3e-123 M Iron Transport-associated domain
KKGFHILH_00941 3e-09 isdH M Iron Transport-associated domain
KKGFHILH_00942 2.2e-89
KKGFHILH_00943 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KKGFHILH_00944 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KKGFHILH_00945 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KKGFHILH_00946 9.7e-52 S Iron-sulfur cluster assembly protein
KKGFHILH_00947 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KKGFHILH_00948 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KKGFHILH_00949 1.6e-295 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KKGFHILH_00950 5.4e-203 xerS L Belongs to the 'phage' integrase family
KKGFHILH_00951 4.1e-67
KKGFHILH_00952 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
KKGFHILH_00953 5.8e-211 M Glycosyl hydrolases family 25
KKGFHILH_00954 4.9e-111 ybbL S ABC transporter, ATP-binding protein
KKGFHILH_00955 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
KKGFHILH_00956 2.5e-191 yrvN L AAA C-terminal domain
KKGFHILH_00957 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KKGFHILH_00958 6.8e-153 treB G phosphotransferase system
KKGFHILH_00959 4.5e-111 treB G phosphotransferase system
KKGFHILH_00960 1.2e-100 treR K UTRA
KKGFHILH_00961 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KKGFHILH_00962 5.7e-18
KKGFHILH_00963 1.5e-239 G Bacterial extracellular solute-binding protein
KKGFHILH_00964 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
KKGFHILH_00965 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
KKGFHILH_00967 0.0 S SLAP domain
KKGFHILH_00968 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
KKGFHILH_00969 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
KKGFHILH_00970 3.4e-42 S RloB-like protein
KKGFHILH_00971 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
KKGFHILH_00972 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
KKGFHILH_00973 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KKGFHILH_00974 1.2e-63 S SIR2-like domain
KKGFHILH_00975 3.2e-10 S Domain of unknown function DUF87
KKGFHILH_00976 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KKGFHILH_00977 1e-30 S cog cog1373
KKGFHILH_00978 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
KKGFHILH_00979 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KKGFHILH_00980 2.7e-83 S Protein of unknown function (DUF1211)
KKGFHILH_00981 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
KKGFHILH_00982 2.8e-119 3.6.1.55 F NUDIX domain
KKGFHILH_00983 3.9e-246 brnQ U Component of the transport system for branched-chain amino acids
KKGFHILH_00984 0.0 L Plasmid pRiA4b ORF-3-like protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)