ORF_ID e_value Gene_name EC_number CAZy COGs Description
ICGGGEAP_00001 0.0 uvrA2 L ABC transporter
ICGGGEAP_00002 1.6e-15 L transposase and inactivated derivatives, IS30 family
ICGGGEAP_00007 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICGGGEAP_00008 6.1e-117 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ICGGGEAP_00009 4.2e-167 whiA K May be required for sporulation
ICGGGEAP_00010 1.1e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ICGGGEAP_00011 8.6e-159 rapZ S Displays ATPase and GTPase activities
ICGGGEAP_00012 9.6e-200
ICGGGEAP_00013 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICGGGEAP_00014 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICGGGEAP_00016 1.4e-113 yfbR S HD containing hydrolase-like enzyme
ICGGGEAP_00017 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ICGGGEAP_00018 1.6e-135 cof S haloacid dehalogenase-like hydrolase
ICGGGEAP_00019 1.7e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICGGGEAP_00020 2.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ICGGGEAP_00021 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICGGGEAP_00022 6.2e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ICGGGEAP_00023 9.7e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICGGGEAP_00024 2.8e-40 yphH S Cupin domain
ICGGGEAP_00025 3.1e-10 yphH S Cupin domain
ICGGGEAP_00026 1.2e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICGGGEAP_00027 2.7e-224 mtnE 2.6.1.83 E Aminotransferase
ICGGGEAP_00028 5.7e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
ICGGGEAP_00029 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICGGGEAP_00030 1.2e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ICGGGEAP_00031 1.4e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICGGGEAP_00032 2.7e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICGGGEAP_00033 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ICGGGEAP_00034 4.1e-53 KT PspC domain protein
ICGGGEAP_00035 2.9e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICGGGEAP_00036 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICGGGEAP_00037 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICGGGEAP_00038 1e-127 comFC S Competence protein
ICGGGEAP_00039 1.9e-250 comFA L Helicase C-terminal domain protein
ICGGGEAP_00040 3.2e-110 yvyE 3.4.13.9 S YigZ family
ICGGGEAP_00041 4.2e-37
ICGGGEAP_00042 0.0 ydaO E amino acid
ICGGGEAP_00043 2.6e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICGGGEAP_00044 1.6e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICGGGEAP_00045 9.7e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICGGGEAP_00046 0.0 uup S ABC transporter, ATP-binding protein
ICGGGEAP_00047 1.2e-169 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICGGGEAP_00048 1.8e-90 bioY S BioY family
ICGGGEAP_00049 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ICGGGEAP_00050 2e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ICGGGEAP_00051 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICGGGEAP_00052 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ICGGGEAP_00053 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICGGGEAP_00054 7.8e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICGGGEAP_00055 5e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICGGGEAP_00056 2.7e-129 IQ reductase
ICGGGEAP_00057 9.7e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ICGGGEAP_00058 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICGGGEAP_00059 4.4e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICGGGEAP_00060 5.7e-74 marR K Transcriptional regulator, MarR family
ICGGGEAP_00061 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICGGGEAP_00063 1.7e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICGGGEAP_00064 4.3e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ICGGGEAP_00065 2.1e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ICGGGEAP_00066 1.3e-212 arcT 2.6.1.1 E Aminotransferase
ICGGGEAP_00067 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
ICGGGEAP_00068 5e-257 E Arginine ornithine antiporter
ICGGGEAP_00069 9.1e-239 arcA 3.5.3.6 E Arginine
ICGGGEAP_00070 3.5e-166 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ICGGGEAP_00071 8.6e-187 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICGGGEAP_00072 3.7e-146 KT YcbB domain
ICGGGEAP_00073 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ICGGGEAP_00074 1.1e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICGGGEAP_00075 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICGGGEAP_00076 1.5e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICGGGEAP_00077 2.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
ICGGGEAP_00078 3e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICGGGEAP_00079 3.4e-55 yabA L Involved in initiation control of chromosome replication
ICGGGEAP_00080 1.3e-190 holB 2.7.7.7 L DNA polymerase III
ICGGGEAP_00081 1.2e-52 yaaQ S Cyclic-di-AMP receptor
ICGGGEAP_00082 5.7e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICGGGEAP_00083 2.4e-21 S Protein of unknown function (DUF2508)
ICGGGEAP_00084 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICGGGEAP_00085 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICGGGEAP_00086 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICGGGEAP_00088 1.4e-73 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICGGGEAP_00089 2e-35 nrdH O Glutaredoxin
ICGGGEAP_00090 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICGGGEAP_00091 4.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICGGGEAP_00092 9.7e-125 IQ reductase
ICGGGEAP_00093 4.6e-87 lacR K Transcriptional regulator
ICGGGEAP_00094 7.5e-208 lacS G Transporter
ICGGGEAP_00095 2.6e-251 lacZ 3.2.1.23 G -beta-galactosidase
ICGGGEAP_00096 8.1e-244 brnQ U Component of the transport system for branched-chain amino acids
ICGGGEAP_00097 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ICGGGEAP_00098 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICGGGEAP_00099 2.9e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ICGGGEAP_00100 5.3e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ICGGGEAP_00101 8.1e-271 cydA 1.10.3.14 C ubiquinol oxidase
ICGGGEAP_00102 1.3e-63
ICGGGEAP_00105 1.2e-112 K Transcriptional regulator
ICGGGEAP_00106 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
ICGGGEAP_00107 9e-53 ysxB J Cysteine protease Prp
ICGGGEAP_00108 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ICGGGEAP_00109 2.3e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICGGGEAP_00110 4.1e-72 yqhY S Asp23 family, cell envelope-related function
ICGGGEAP_00111 4.4e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICGGGEAP_00112 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICGGGEAP_00113 2.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICGGGEAP_00114 2.9e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICGGGEAP_00115 7.6e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICGGGEAP_00116 2.4e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ICGGGEAP_00117 6.2e-76 argR K Regulates arginine biosynthesis genes
ICGGGEAP_00118 5.5e-303 recN L May be involved in recombinational repair of damaged DNA
ICGGGEAP_00119 3.3e-15
ICGGGEAP_00120 6.7e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ICGGGEAP_00121 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICGGGEAP_00122 2.2e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICGGGEAP_00123 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICGGGEAP_00124 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICGGGEAP_00125 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICGGGEAP_00126 6.7e-128 stp 3.1.3.16 T phosphatase
ICGGGEAP_00127 0.0 KLT serine threonine protein kinase
ICGGGEAP_00128 1.6e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICGGGEAP_00129 3.3e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ICGGGEAP_00130 2.3e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
ICGGGEAP_00131 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ICGGGEAP_00132 3.6e-58 asp S Asp23 family, cell envelope-related function
ICGGGEAP_00133 2.1e-302 yloV S DAK2 domain fusion protein YloV
ICGGGEAP_00134 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICGGGEAP_00135 4.5e-162 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICGGGEAP_00136 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICGGGEAP_00137 3.4e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICGGGEAP_00138 0.0 smc D Required for chromosome condensation and partitioning
ICGGGEAP_00139 5.1e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICGGGEAP_00140 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICGGGEAP_00141 1.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICGGGEAP_00142 6.6e-119 L helicase activity
ICGGGEAP_00144 1.5e-221 norB EGP Major Facilitator
ICGGGEAP_00145 3.8e-43 K Bacterial regulatory proteins, tetR family
ICGGGEAP_00147 9.2e-141 pgi 5.3.1.9 G Belongs to the GPI family
ICGGGEAP_00149 3.9e-84 K GNAT family
ICGGGEAP_00150 7e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ICGGGEAP_00151 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
ICGGGEAP_00152 9.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICGGGEAP_00153 2e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
ICGGGEAP_00155 1e-56
ICGGGEAP_00157 3.5e-08
ICGGGEAP_00158 1.5e-77 K Winged helix DNA-binding domain
ICGGGEAP_00159 0.0 lmrA V ABC transporter, ATP-binding protein
ICGGGEAP_00160 0.0 yfiC V ABC transporter
ICGGGEAP_00161 2e-191 ampC V Beta-lactamase
ICGGGEAP_00162 1.6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICGGGEAP_00163 2.7e-46
ICGGGEAP_00164 5.8e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
ICGGGEAP_00165 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
ICGGGEAP_00166 5.5e-109 tdk 2.7.1.21 F thymidine kinase
ICGGGEAP_00167 1.2e-154 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICGGGEAP_00168 3.9e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICGGGEAP_00169 1.4e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICGGGEAP_00170 7.8e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICGGGEAP_00171 3.6e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICGGGEAP_00172 2.3e-180 yibE S overlaps another CDS with the same product name
ICGGGEAP_00173 9.5e-125 yibF S overlaps another CDS with the same product name
ICGGGEAP_00174 5.4e-218 pyrP F Permease
ICGGGEAP_00175 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
ICGGGEAP_00176 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICGGGEAP_00177 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICGGGEAP_00178 2.2e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICGGGEAP_00179 3.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICGGGEAP_00180 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICGGGEAP_00181 3.7e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICGGGEAP_00182 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ICGGGEAP_00183 2.8e-29 S Protein of unknown function (DUF1146)
ICGGGEAP_00184 6.6e-216 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
ICGGGEAP_00185 2.9e-182 mbl D Cell shape determining protein MreB Mrl
ICGGGEAP_00186 7.9e-32 S Protein of unknown function (DUF2969)
ICGGGEAP_00187 2.4e-220 rodA D Belongs to the SEDS family
ICGGGEAP_00189 2.7e-177 S Protein of unknown function (DUF2785)
ICGGGEAP_00190 1.2e-213 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ICGGGEAP_00191 6.4e-179 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ICGGGEAP_00192 4.4e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICGGGEAP_00193 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICGGGEAP_00194 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICGGGEAP_00195 3.2e-50 ylxQ J ribosomal protein
ICGGGEAP_00196 1.4e-47 ylxR K Protein of unknown function (DUF448)
ICGGGEAP_00197 8.3e-224 nusA K Participates in both transcription termination and antitermination
ICGGGEAP_00198 9.5e-83 rimP J Required for maturation of 30S ribosomal subunits
ICGGGEAP_00199 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICGGGEAP_00200 5.8e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICGGGEAP_00201 3.8e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICGGGEAP_00202 1.3e-205 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ICGGGEAP_00203 3.3e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
ICGGGEAP_00204 1.2e-211 argD 2.6.1.11, 2.6.1.17 E acetylornithine
ICGGGEAP_00205 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICGGGEAP_00206 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICGGGEAP_00207 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ICGGGEAP_00208 1.8e-134 cdsA 2.7.7.41 I Belongs to the CDS family
ICGGGEAP_00209 3.6e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICGGGEAP_00210 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICGGGEAP_00211 3.8e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ICGGGEAP_00212 5.5e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICGGGEAP_00213 3.3e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
ICGGGEAP_00214 5.1e-47 yazA L GIY-YIG catalytic domain protein
ICGGGEAP_00215 1.1e-133 yabB 2.1.1.223 L Methyltransferase small domain
ICGGGEAP_00216 3e-113 plsC 2.3.1.51 I Acyltransferase
ICGGGEAP_00217 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
ICGGGEAP_00218 5.4e-37 ynzC S UPF0291 protein
ICGGGEAP_00219 1.2e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICGGGEAP_00220 1.6e-213 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ICGGGEAP_00221 8.9e-52 lutA C Cysteine-rich domain
ICGGGEAP_00222 6.7e-232 lutB C 4Fe-4S dicluster domain
ICGGGEAP_00224 1.6e-25 yitW S Iron-sulfur cluster assembly protein
ICGGGEAP_00225 4.6e-91 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ICGGGEAP_00226 1.3e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
ICGGGEAP_00227 6.3e-229 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ICGGGEAP_00228 1.4e-15 K transcriptional regulator
ICGGGEAP_00229 3.4e-162 K AI-2E family transporter
ICGGGEAP_00230 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ICGGGEAP_00231 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICGGGEAP_00232 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICGGGEAP_00233 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICGGGEAP_00234 7.5e-99 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
ICGGGEAP_00235 2e-230 S response to antibiotic
ICGGGEAP_00236 2e-96 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
ICGGGEAP_00237 4.3e-66 IQ Dehydrogenase
ICGGGEAP_00238 5.1e-19 K HxlR-like helix-turn-helix
ICGGGEAP_00239 7.2e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ICGGGEAP_00240 8.9e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICGGGEAP_00241 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICGGGEAP_00242 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICGGGEAP_00243 1.8e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICGGGEAP_00244 7.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ICGGGEAP_00245 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICGGGEAP_00246 8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ICGGGEAP_00247 2.1e-238 purD 6.3.4.13 F Belongs to the GARS family
ICGGGEAP_00248 6.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICGGGEAP_00249 1.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
ICGGGEAP_00250 9e-176
ICGGGEAP_00251 1.4e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICGGGEAP_00252 9.5e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ICGGGEAP_00253 2e-98 copA 3.6.3.54 P P-type ATPase
ICGGGEAP_00254 3.6e-45 EGP Major facilitator Superfamily
ICGGGEAP_00255 2.6e-76 EGP Major facilitator Superfamily
ICGGGEAP_00256 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
ICGGGEAP_00257 4.5e-91 pstS P Phosphate ABC transporter substrate-binding protein, PhoT family
ICGGGEAP_00258 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
ICGGGEAP_00259 1.3e-103 pstA P Phosphate transport system permease protein PstA
ICGGGEAP_00260 1.6e-95 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICGGGEAP_00261 1.1e-203 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICGGGEAP_00262 3.6e-210 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ICGGGEAP_00263 5.3e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ICGGGEAP_00264 3.9e-165 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ICGGGEAP_00265 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ICGGGEAP_00266 6.2e-88 ypmB S Protein conserved in bacteria
ICGGGEAP_00267 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ICGGGEAP_00268 1.7e-131 dnaD L DnaD domain protein
ICGGGEAP_00269 3.7e-121 ypuA S Protein of unknown function (DUF1002)
ICGGGEAP_00270 1.7e-176 C Aldo keto reductase family protein
ICGGGEAP_00271 1.8e-159 EG EamA-like transporter family
ICGGGEAP_00272 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ICGGGEAP_00273 1.9e-115 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICGGGEAP_00274 1.1e-107 ypsA S Belongs to the UPF0398 family
ICGGGEAP_00275 2.3e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICGGGEAP_00276 0.0 tetP J elongation factor G
ICGGGEAP_00277 3.4e-211 S Type IV secretion-system coupling protein DNA-binding domain
ICGGGEAP_00278 8.9e-83 F Hydrolase, NUDIX family
ICGGGEAP_00279 6.1e-213 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ICGGGEAP_00280 1.8e-192 ytjP 3.5.1.18 E Dipeptidase
ICGGGEAP_00281 2.4e-204 arcD S C4-dicarboxylate anaerobic carrier
ICGGGEAP_00282 8e-258 nylA 3.5.1.4 J Belongs to the amidase family
ICGGGEAP_00283 3.7e-75 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
ICGGGEAP_00284 6e-73 O OsmC-like protein
ICGGGEAP_00285 2.6e-74 K Transcriptional regulator
ICGGGEAP_00286 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
ICGGGEAP_00287 1.7e-106 proWZ P ABC transporter permease
ICGGGEAP_00288 3.2e-141 proV E ABC transporter, ATP-binding protein
ICGGGEAP_00289 1.3e-100 proW P ABC transporter, permease protein
ICGGGEAP_00290 4.8e-148 C Zinc-binding dehydrogenase
ICGGGEAP_00291 9e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
ICGGGEAP_00292 2.5e-200 xerS L Belongs to the 'phage' integrase family
ICGGGEAP_00293 1.2e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
ICGGGEAP_00294 2.2e-79 hmpT S ECF-type riboflavin transporter, S component
ICGGGEAP_00295 3.6e-165 1.1.1.346 C Aldo keto reductase
ICGGGEAP_00296 2e-158 S DUF218 domain
ICGGGEAP_00297 2.2e-11 S Uncharacterized protein conserved in bacteria (DUF2316)
ICGGGEAP_00298 6e-61 K Acetyltransferase (GNAT) domain
ICGGGEAP_00299 1.5e-160 I alpha/beta hydrolase fold
ICGGGEAP_00301 2.6e-65 mutR K Transcriptional activator, Rgg GadR MutR family
ICGGGEAP_00302 3.3e-242 yhjX P Major Facilitator Superfamily
ICGGGEAP_00303 1.8e-40 S Protein of unknown function (DUF554)
ICGGGEAP_00304 4.5e-41 S Protein of unknown function (DUF554)
ICGGGEAP_00305 2.4e-253 rarA L recombination factor protein RarA
ICGGGEAP_00307 0.0 oppD EP Psort location Cytoplasmic, score
ICGGGEAP_00308 4.4e-241 codA 3.5.4.1 F cytosine deaminase
ICGGGEAP_00309 4e-243 U Belongs to the purine-cytosine permease (2.A.39) family
ICGGGEAP_00310 8.4e-81 yebR 1.8.4.14 T GAF domain-containing protein
ICGGGEAP_00311 6.3e-75 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ICGGGEAP_00312 5.5e-74 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICGGGEAP_00313 1.5e-70 yqkB S Belongs to the HesB IscA family
ICGGGEAP_00314 8.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
ICGGGEAP_00315 5.8e-94 S Protein of unknown function (DUF1440)
ICGGGEAP_00316 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICGGGEAP_00317 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICGGGEAP_00318 4.7e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICGGGEAP_00319 9e-172 lacX 5.1.3.3 G Aldose 1-epimerase
ICGGGEAP_00320 2.4e-153 D DNA integration
ICGGGEAP_00321 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICGGGEAP_00322 2.9e-162 dprA LU DNA protecting protein DprA
ICGGGEAP_00323 2.3e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICGGGEAP_00324 7.8e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICGGGEAP_00325 3.1e-36 yozE S Belongs to the UPF0346 family
ICGGGEAP_00326 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ICGGGEAP_00327 1.3e-165 ypmR E lipolytic protein G-D-S-L family
ICGGGEAP_00328 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
ICGGGEAP_00329 5.2e-215 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
ICGGGEAP_00330 7.6e-152 DegV S EDD domain protein, DegV family
ICGGGEAP_00331 7.7e-109 hlyIII S protein, hemolysin III
ICGGGEAP_00332 6.1e-93 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICGGGEAP_00333 2.3e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICGGGEAP_00334 0.0 yfmR S ABC transporter, ATP-binding protein
ICGGGEAP_00335 2.1e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICGGGEAP_00336 3.3e-155 xerD L Phage integrase, N-terminal SAM-like domain
ICGGGEAP_00337 5e-232 S Tetratricopeptide repeat protein
ICGGGEAP_00338 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICGGGEAP_00339 1.8e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ICGGGEAP_00340 8.3e-208 rpsA 1.17.7.4 J Ribosomal protein S1
ICGGGEAP_00341 3.2e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ICGGGEAP_00342 4.2e-29 M Lysin motif
ICGGGEAP_00343 1e-276 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ICGGGEAP_00344 1.2e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
ICGGGEAP_00345 1.2e-79 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICGGGEAP_00346 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICGGGEAP_00347 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICGGGEAP_00348 8.7e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICGGGEAP_00349 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICGGGEAP_00350 1.6e-157 xerD D recombinase XerD
ICGGGEAP_00351 6.1e-168 cvfB S S1 domain
ICGGGEAP_00352 9.1e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ICGGGEAP_00353 0.0 dnaE 2.7.7.7 L DNA polymerase
ICGGGEAP_00355 7.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ICGGGEAP_00356 6.7e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICGGGEAP_00357 1.5e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
ICGGGEAP_00358 4.4e-118 ktrA P domain protein
ICGGGEAP_00359 5.7e-226 ktrB P Potassium uptake protein
ICGGGEAP_00360 1.3e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICGGGEAP_00361 1.9e-217 patA 2.6.1.1 E Aminotransferase
ICGGGEAP_00362 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICGGGEAP_00363 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICGGGEAP_00364 1.9e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICGGGEAP_00365 3.3e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICGGGEAP_00366 5.9e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICGGGEAP_00367 3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
ICGGGEAP_00368 7.1e-173 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICGGGEAP_00369 1.5e-166 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICGGGEAP_00370 3.2e-48 L PFAM Integrase catalytic region
ICGGGEAP_00371 1.3e-34 ypaA S Protein of unknown function (DUF1304)
ICGGGEAP_00372 4.4e-200 L Belongs to the 'phage' integrase family
ICGGGEAP_00373 1.5e-14
ICGGGEAP_00374 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICGGGEAP_00375 2.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ICGGGEAP_00376 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICGGGEAP_00377 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICGGGEAP_00378 1.6e-252 yifK E Amino acid permease
ICGGGEAP_00379 6.4e-290 clcA P chloride
ICGGGEAP_00380 4.5e-33 secG U Preprotein translocase
ICGGGEAP_00381 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICGGGEAP_00382 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICGGGEAP_00383 1.4e-109 yxjI
ICGGGEAP_00384 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICGGGEAP_00385 5.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ICGGGEAP_00386 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ICGGGEAP_00387 3.3e-89 K Acetyltransferase (GNAT) domain
ICGGGEAP_00388 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
ICGGGEAP_00389 5.7e-166 murB 1.3.1.98 M Cell wall formation
ICGGGEAP_00390 8.7e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICGGGEAP_00391 7.7e-115 ybbR S YbbR-like protein
ICGGGEAP_00392 2.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICGGGEAP_00393 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICGGGEAP_00394 7.3e-52
ICGGGEAP_00395 9.3e-211 oatA I Acyltransferase
ICGGGEAP_00396 4.5e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
ICGGGEAP_00397 7.5e-74 lytE M Lysin motif
ICGGGEAP_00398 3.6e-45
ICGGGEAP_00400 1.7e-38
ICGGGEAP_00401 6.3e-154 ps461 3.5.1.104 M hydrolase, family 25
ICGGGEAP_00402 3.9e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
ICGGGEAP_00403 6.5e-11
ICGGGEAP_00405 3.2e-57
ICGGGEAP_00406 3.4e-32 S GDSL-like Lipase/Acylhydrolase
ICGGGEAP_00409 4.7e-87 spoIVFA GT2,GT4 D peptidase
ICGGGEAP_00410 6.1e-138 rny D peptidase
ICGGGEAP_00411 1e-79 S Phage tail protein
ICGGGEAP_00412 3.4e-187 M Phage tail tape measure protein TP901
ICGGGEAP_00413 4.8e-27
ICGGGEAP_00414 9.4e-49 S Phage tail tube protein
ICGGGEAP_00415 2.4e-23
ICGGGEAP_00416 3.1e-19
ICGGGEAP_00417 5.1e-33 S Phage head-tail joining protein
ICGGGEAP_00418 1.3e-29 S Phage gp6-like head-tail connector protein
ICGGGEAP_00419 2.5e-121 S Phage capsid family
ICGGGEAP_00420 1.2e-79 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
ICGGGEAP_00421 2.3e-144 S portal protein
ICGGGEAP_00423 1.8e-267 S Phage Terminase
ICGGGEAP_00424 3.3e-40 L Phage terminase, small subunit
ICGGGEAP_00426 6.9e-11 D nuclear chromosome segregation
ICGGGEAP_00432 1.5e-239 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
ICGGGEAP_00433 5e-72 treR K UTRA
ICGGGEAP_00434 7.5e-240 treB G phosphotransferase system
ICGGGEAP_00435 4.7e-43 IQ reductase
ICGGGEAP_00436 1e-99 K DNA-templated transcription, initiation
ICGGGEAP_00438 0.0 L Type III restriction enzyme, res subunit
ICGGGEAP_00439 1.6e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
ICGGGEAP_00441 5.5e-89 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICGGGEAP_00442 2.4e-196 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICGGGEAP_00443 2.1e-161 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ICGGGEAP_00444 3.6e-115 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ICGGGEAP_00445 5.4e-90 deoR K sugar-binding domain protein
ICGGGEAP_00446 3.8e-78 ubiE Q Mycolic acid cyclopropane synthetase
ICGGGEAP_00447 1.2e-29 1.14.12.17 S Cupin 2, conserved barrel domain protein
ICGGGEAP_00448 8.2e-10 K Transcriptional regulator
ICGGGEAP_00450 3.4e-20 K Transcriptional regulator
ICGGGEAP_00451 2.2e-24 K DNA-binding helix-turn-helix protein
ICGGGEAP_00452 2.2e-236 cycA E Amino acid permease
ICGGGEAP_00453 1.1e-202 F Permease
ICGGGEAP_00454 3.6e-165 luxE 6.2.1.19 H Acyl-protein synthetase, LuxE
ICGGGEAP_00455 7.2e-198 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
ICGGGEAP_00456 1.6e-111 IQ KR domain
ICGGGEAP_00457 9.2e-23 L Plasmid pRiA4b ORF-3-like protein
ICGGGEAP_00461 1.9e-133 D nuclear chromosome segregation
ICGGGEAP_00462 4.5e-256 dtpT U amino acid peptide transporter
ICGGGEAP_00463 2.1e-162 yjjH S Calcineurin-like phosphoesterase
ICGGGEAP_00466 2e-112
ICGGGEAP_00467 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ICGGGEAP_00468 1.6e-126 gntR1 K UbiC transcription regulator-associated domain protein
ICGGGEAP_00469 9.4e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICGGGEAP_00470 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICGGGEAP_00471 0.0 yhgF K Tex-like protein N-terminal domain protein
ICGGGEAP_00472 1.6e-84 ydcK S Belongs to the SprT family
ICGGGEAP_00474 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
ICGGGEAP_00475 1.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
ICGGGEAP_00476 1.9e-167 mleP2 S Sodium Bile acid symporter family
ICGGGEAP_00477 5.7e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICGGGEAP_00478 2.8e-165 I alpha/beta hydrolase fold
ICGGGEAP_00479 3.4e-56 S Sel1-like repeats.
ICGGGEAP_00480 1.8e-62 yjbR S YjbR
ICGGGEAP_00481 9.2e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICGGGEAP_00482 4.4e-38 S Domain of unknown function (DUF3841)
ICGGGEAP_00483 4.5e-112 licT K CAT RNA binding domain
ICGGGEAP_00484 4.7e-269 bglP 2.7.1.211 G phosphotransferase system
ICGGGEAP_00485 1.4e-262 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICGGGEAP_00486 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
ICGGGEAP_00487 1e-22 D mRNA cleavage
ICGGGEAP_00488 4.4e-171 S Phosphotransferase system, EIIC
ICGGGEAP_00490 5.1e-142 S Oxidoreductase family, NAD-binding Rossmann fold
ICGGGEAP_00492 2.1e-191 nhaC C Na H antiporter NhaC
ICGGGEAP_00494 1e-73 ddaH 3.5.3.18 E Amidinotransferase
ICGGGEAP_00495 1.6e-88 S Aminoacyl-tRNA editing domain
ICGGGEAP_00496 4.9e-306 mco Q Multicopper oxidase
ICGGGEAP_00497 9.1e-50 K 2 iron, 2 sulfur cluster binding
ICGGGEAP_00498 2.9e-86 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
ICGGGEAP_00499 4.3e-113 Q Methyltransferase domain
ICGGGEAP_00501 3.3e-101 S CAAX protease self-immunity
ICGGGEAP_00502 2.9e-93 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICGGGEAP_00503 5.4e-11 fsr EGP Major Facilitator Superfamily
ICGGGEAP_00504 1.4e-81 fsr EGP Major Facilitator Superfamily
ICGGGEAP_00505 4.7e-64 K helix_turn_helix, arabinose operon control protein
ICGGGEAP_00506 8.8e-101 K helix_turn_helix multiple antibiotic resistance protein
ICGGGEAP_00507 4e-181 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICGGGEAP_00508 1e-104
ICGGGEAP_00509 2.4e-83 dps P Belongs to the Dps family
ICGGGEAP_00510 2e-302 ybiT S ABC transporter, ATP-binding protein
ICGGGEAP_00512 8.7e-33 yneR S Belongs to the HesB IscA family
ICGGGEAP_00513 1.7e-134 S NADPH-dependent FMN reductase
ICGGGEAP_00514 6.9e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICGGGEAP_00515 1.3e-157 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICGGGEAP_00516 1.3e-102 yvdD 3.2.2.10 S Belongs to the LOG family
ICGGGEAP_00517 4.9e-63 S Domain of unknown function (DUF4828)
ICGGGEAP_00518 1.3e-190 mocA S Oxidoreductase
ICGGGEAP_00519 1.7e-230 yfmL 3.6.4.13 L DEAD DEAH box helicase
ICGGGEAP_00521 3e-75 gtcA S Teichoic acid glycosylation protein
ICGGGEAP_00522 8.5e-78 fld C Flavodoxin
ICGGGEAP_00523 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
ICGGGEAP_00524 0.0 XK27_08315 M Sulfatase
ICGGGEAP_00525 7.8e-139 yihY S Belongs to the UPF0761 family
ICGGGEAP_00526 3.8e-31 S Protein of unknown function (DUF2922)
ICGGGEAP_00527 1.3e-07
ICGGGEAP_00528 5.1e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
ICGGGEAP_00529 1.1e-118 rfbP M Bacterial sugar transferase
ICGGGEAP_00530 5.1e-147 cps1D M Domain of unknown function (DUF4422)
ICGGGEAP_00531 4.2e-95 cps3F
ICGGGEAP_00532 4.5e-45 M biosynthesis protein
ICGGGEAP_00533 2.1e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
ICGGGEAP_00534 4.2e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
ICGGGEAP_00535 9.7e-72 S enterobacterial common antigen metabolic process
ICGGGEAP_00536 7.4e-76 S Psort location CytoplasmicMembrane, score
ICGGGEAP_00537 1.6e-54 yphJ 4.1.1.44 S decarboxylase
ICGGGEAP_00538 5.3e-53 azlD E Branched-chain amino acid transport
ICGGGEAP_00539 1.2e-62 azlC E azaleucine resistance protein AzlC
ICGGGEAP_00540 1.1e-30 azlC E azaleucine resistance protein AzlC
ICGGGEAP_00541 2.2e-282 thrC 4.2.3.1 E Threonine synthase
ICGGGEAP_00542 3.6e-230 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
ICGGGEAP_00543 1.3e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICGGGEAP_00544 3.3e-97 K Acetyltransferase (GNAT) domain
ICGGGEAP_00545 4.5e-112 ylbE GM NAD(P)H-binding
ICGGGEAP_00546 1.2e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICGGGEAP_00547 2.1e-123 S Belongs to the UPF0246 family
ICGGGEAP_00548 1.2e-95
ICGGGEAP_00549 3.2e-161 degV S EDD domain protein, DegV family
ICGGGEAP_00550 0.0 FbpA K Fibronectin-binding protein
ICGGGEAP_00551 1.3e-94 P nitric oxide dioxygenase activity
ICGGGEAP_00552 1.2e-49 C Flavodoxin
ICGGGEAP_00553 5.3e-36 S Bacterial transferase hexapeptide (six repeats)
ICGGGEAP_00554 3.7e-74 akr5f 1.1.1.346 S aldo keto reductase
ICGGGEAP_00555 2e-64 S Enoyl-(Acyl carrier protein) reductase
ICGGGEAP_00556 4.6e-163 K Bacterial regulatory helix-turn-helix protein, lysR family
ICGGGEAP_00557 3.8e-108 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
ICGGGEAP_00558 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICGGGEAP_00559 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
ICGGGEAP_00560 6.5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICGGGEAP_00561 5.6e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICGGGEAP_00562 1.7e-70 esbA S Family of unknown function (DUF5322)
ICGGGEAP_00563 1.2e-70 rnhA 3.1.26.4 L Ribonuclease HI
ICGGGEAP_00564 3.4e-106 XK27_02070 S Nitroreductase family
ICGGGEAP_00565 5.7e-155 yckB ET Belongs to the bacterial solute-binding protein 3 family
ICGGGEAP_00566 7.2e-116 yecS E ABC transporter permease
ICGGGEAP_00567 2.4e-28 M Glycosyltransferase like family 2
ICGGGEAP_00569 2.9e-176 yobV1 K WYL domain
ICGGGEAP_00570 1.3e-241 XK27_08635 S UPF0210 protein
ICGGGEAP_00571 2.5e-40 gcvR T Belongs to the UPF0237 family
ICGGGEAP_00572 8.2e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICGGGEAP_00573 1.7e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICGGGEAP_00574 6.9e-203 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
ICGGGEAP_00575 2.1e-216 G Transporter, major facilitator family protein
ICGGGEAP_00576 5.9e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICGGGEAP_00577 6.9e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICGGGEAP_00578 5.7e-54 ydiI Q Thioesterase superfamily
ICGGGEAP_00580 6.5e-183 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ICGGGEAP_00581 1.7e-107 citR K sugar-binding domain protein
ICGGGEAP_00582 6.8e-151 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICGGGEAP_00583 2.2e-110 S Membrane transport protein
ICGGGEAP_00584 3.3e-88 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICGGGEAP_00585 7e-36 citD C Covalent carrier of the coenzyme of citrate lyase
ICGGGEAP_00586 2.5e-145 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
ICGGGEAP_00587 2.5e-238 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
ICGGGEAP_00588 4.4e-136 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ICGGGEAP_00589 1.8e-70 ydjP I Alpha/beta hydrolase family
ICGGGEAP_00590 5.7e-106 L Integrase
ICGGGEAP_00591 1.6e-44 K transcriptional regulator
ICGGGEAP_00592 4.6e-88 GM NmrA-like family
ICGGGEAP_00593 4.9e-36 C Flavodoxin
ICGGGEAP_00594 6.1e-122 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICGGGEAP_00595 5.2e-79
ICGGGEAP_00597 5.6e-186 ydaM M Glycosyl transferase family group 2
ICGGGEAP_00598 1.1e-121 G Glycosyl hydrolases family 8
ICGGGEAP_00599 7.2e-142 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
ICGGGEAP_00600 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_00601 1.2e-294 ybeC E amino acid
ICGGGEAP_00602 4e-133 pnuC H nicotinamide mononucleotide transporter
ICGGGEAP_00603 8.6e-204 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ICGGGEAP_00604 4.4e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICGGGEAP_00605 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ICGGGEAP_00606 3.6e-117 dedA S SNARE associated Golgi protein
ICGGGEAP_00607 0.0 helD 3.6.4.12 L DNA helicase
ICGGGEAP_00608 2.1e-160 EG EamA-like transporter family
ICGGGEAP_00609 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICGGGEAP_00610 8.3e-134 IQ Dehydrogenase reductase
ICGGGEAP_00611 1.8e-101 2.3.1.128 K acetyltransferase
ICGGGEAP_00612 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
ICGGGEAP_00613 8.4e-131 sptS 2.7.13.3 T Histidine kinase
ICGGGEAP_00614 1.4e-79 K response regulator
ICGGGEAP_00615 4.3e-112 2.7.6.5 T Region found in RelA / SpoT proteins
ICGGGEAP_00616 1.1e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ICGGGEAP_00617 5.3e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ICGGGEAP_00618 1.7e-153 yitU 3.1.3.104 S hydrolase
ICGGGEAP_00619 7.7e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICGGGEAP_00620 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICGGGEAP_00621 9.6e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICGGGEAP_00622 1.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICGGGEAP_00623 4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICGGGEAP_00624 2.3e-72 ycsI S Protein of unknown function (DUF1445)
ICGGGEAP_00627 8.7e-08 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICGGGEAP_00628 2.4e-17 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICGGGEAP_00633 2.2e-67 ubiD 4.1.1.98 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
ICGGGEAP_00634 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICGGGEAP_00635 3.7e-260 yfnA E Amino Acid
ICGGGEAP_00636 1.4e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ICGGGEAP_00637 1.8e-87 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICGGGEAP_00638 5.4e-40 ylqC S Belongs to the UPF0109 family
ICGGGEAP_00639 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ICGGGEAP_00640 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
ICGGGEAP_00641 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICGGGEAP_00642 6.1e-152 pstA P Phosphate transport system permease protein PstA
ICGGGEAP_00643 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
ICGGGEAP_00644 5.1e-159 pstS P Phosphate
ICGGGEAP_00645 3.7e-128 K Transcriptional regulatory protein, C-terminal domain protein
ICGGGEAP_00646 1.6e-68
ICGGGEAP_00648 6.4e-246 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
ICGGGEAP_00649 3.7e-51 trxA O Belongs to the thioredoxin family
ICGGGEAP_00650 1.9e-151 mleP3 S Membrane transport protein
ICGGGEAP_00652 8.2e-241 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICGGGEAP_00653 6.3e-239 yfnA E amino acid
ICGGGEAP_00654 4.6e-61 S NADPH-dependent FMN reductase
ICGGGEAP_00656 3.6e-154 L Thioesterase-like superfamily
ICGGGEAP_00657 3.6e-51 lacA S transferase hexapeptide repeat
ICGGGEAP_00658 6.2e-260 argH 4.3.2.1 E argininosuccinate lyase
ICGGGEAP_00659 1.6e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICGGGEAP_00660 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICGGGEAP_00661 1.2e-97 K Transcriptional regulator
ICGGGEAP_00662 2e-15 L Transposase
ICGGGEAP_00664 4.4e-48 S FMN_bind
ICGGGEAP_00665 0.0 yhcA V ABC transporter, ATP-binding protein
ICGGGEAP_00666 2e-115 bm3R1 K Bacterial regulatory proteins, tetR family
ICGGGEAP_00667 5.4e-50 ybjQ S Belongs to the UPF0145 family
ICGGGEAP_00669 3e-19 S Plasmid maintenance system killer
ICGGGEAP_00670 1.2e-27 rocF 3.5.3.1, 3.5.3.11 E Arginase family
ICGGGEAP_00671 1.3e-21 rocF 3.5.3.1, 3.5.3.11 E Arginase family
ICGGGEAP_00672 7.2e-17 rocF 3.5.3.1, 3.5.3.11 E Arginase family
ICGGGEAP_00673 2.2e-58 1.3.1.9 S Nitronate monooxygenase
ICGGGEAP_00674 4.3e-95 1.3.1.9 S Nitronate monooxygenase
ICGGGEAP_00675 1.5e-52 K Helix-turn-helix domain
ICGGGEAP_00676 8e-105 S Domain of unknown function (DUF4767)
ICGGGEAP_00677 1.1e-79
ICGGGEAP_00678 9.3e-09 S Domain of unknown function (DUF4767)
ICGGGEAP_00679 3.5e-60
ICGGGEAP_00680 2.3e-207 lmrP E Major Facilitator Superfamily
ICGGGEAP_00681 3.1e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ICGGGEAP_00682 2e-74 rplI J Binds to the 23S rRNA
ICGGGEAP_00683 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ICGGGEAP_00684 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICGGGEAP_00685 7.4e-87 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICGGGEAP_00686 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ICGGGEAP_00687 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICGGGEAP_00688 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICGGGEAP_00689 5.3e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICGGGEAP_00690 2.2e-34 yaaA S S4 domain protein YaaA
ICGGGEAP_00691 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICGGGEAP_00692 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICGGGEAP_00694 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ICGGGEAP_00695 1.9e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICGGGEAP_00696 9.8e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICGGGEAP_00697 1.2e-133 jag S R3H domain protein
ICGGGEAP_00698 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICGGGEAP_00699 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICGGGEAP_00700 6.8e-130 K response regulator
ICGGGEAP_00701 0.0 vicK 2.7.13.3 T Histidine kinase
ICGGGEAP_00702 1.9e-239 yycH S YycH protein
ICGGGEAP_00703 8e-143 yycI S YycH protein
ICGGGEAP_00704 6e-154 vicX 3.1.26.11 S domain protein
ICGGGEAP_00705 3e-208 htrA 3.4.21.107 O serine protease
ICGGGEAP_00706 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICGGGEAP_00707 1.3e-70 K Transcriptional regulator
ICGGGEAP_00708 3.2e-175 malR K Transcriptional regulator, LacI family
ICGGGEAP_00709 2.8e-249 malT G Major Facilitator
ICGGGEAP_00710 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ICGGGEAP_00711 6.9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ICGGGEAP_00712 1.7e-88 ysdA CP transmembrane transport
ICGGGEAP_00713 8.3e-72 natA S ABC transporter, ATP-binding protein
ICGGGEAP_00714 4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ICGGGEAP_00715 5.4e-183 D Alpha beta
ICGGGEAP_00716 2.7e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_00717 2e-214 patA 2.6.1.1 E Aminotransferase
ICGGGEAP_00718 1e-34
ICGGGEAP_00719 0.0 clpL O associated with various cellular activities
ICGGGEAP_00720 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICGGGEAP_00721 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ICGGGEAP_00722 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ICGGGEAP_00723 5.7e-163 yvgN C Aldo keto reductase
ICGGGEAP_00724 7.7e-286 glpQ 3.1.4.46 C phosphodiesterase
ICGGGEAP_00725 8.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
ICGGGEAP_00726 3.3e-179 ybhR V ABC transporter
ICGGGEAP_00727 4.4e-124 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
ICGGGEAP_00728 1.3e-91 K transcriptional regulator
ICGGGEAP_00729 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICGGGEAP_00730 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICGGGEAP_00731 5.4e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ICGGGEAP_00732 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICGGGEAP_00733 1.2e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICGGGEAP_00734 1.1e-107 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICGGGEAP_00735 1.5e-46
ICGGGEAP_00736 6e-272 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
ICGGGEAP_00737 8.7e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
ICGGGEAP_00738 5.1e-148 metQ1 P Belongs to the nlpA lipoprotein family
ICGGGEAP_00739 2.8e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICGGGEAP_00740 8.4e-96 metI P ABC transporter permease
ICGGGEAP_00741 5e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICGGGEAP_00742 4.4e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICGGGEAP_00743 2.5e-56 brnQ U Component of the transport system for branched-chain amino acids
ICGGGEAP_00744 2.2e-117 brnQ U Component of the transport system for branched-chain amino acids
ICGGGEAP_00745 1.4e-122 iolS C Aldo keto reductase
ICGGGEAP_00746 1.4e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICGGGEAP_00747 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICGGGEAP_00748 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
ICGGGEAP_00749 2.4e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICGGGEAP_00751 1.8e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICGGGEAP_00752 0.0 sbcC L Putative exonuclease SbcCD, C subunit
ICGGGEAP_00753 1.3e-227 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICGGGEAP_00754 3e-187 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICGGGEAP_00756 4.4e-224 glnP P ABC transporter
ICGGGEAP_00757 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICGGGEAP_00758 1.3e-249 cycA E Amino acid permease
ICGGGEAP_00759 3.2e-212 nupG F Nucleoside transporter
ICGGGEAP_00760 2.2e-144 rihC 3.2.2.1 F Nucleoside
ICGGGEAP_00761 2.6e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ICGGGEAP_00762 1.7e-157 noc K Belongs to the ParB family
ICGGGEAP_00763 3e-145 spo0J K Belongs to the ParB family
ICGGGEAP_00764 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
ICGGGEAP_00765 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICGGGEAP_00766 5e-134 XK27_01040 S Protein of unknown function (DUF1129)
ICGGGEAP_00767 1e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICGGGEAP_00768 4.5e-31 L HNH nucleases
ICGGGEAP_00769 9.9e-33 doc S Fic/DOC family
ICGGGEAP_00770 1.5e-52 gepA K Protein of unknown function (DUF4065)
ICGGGEAP_00771 1e-20
ICGGGEAP_00777 2.9e-41 rusA L Endodeoxyribonuclease RusA
ICGGGEAP_00780 4.6e-42 dnaC 3.4.21.53 L IstB-like ATP binding protein
ICGGGEAP_00781 5.4e-106 S calcium ion binding
ICGGGEAP_00782 5.4e-71 S Putative HNHc nuclease
ICGGGEAP_00783 3.4e-34 S Single-strand binding protein family
ICGGGEAP_00784 3.9e-26 S Erf family
ICGGGEAP_00789 3.3e-10
ICGGGEAP_00790 7.2e-10 S Domain of unknown function (DUF771)
ICGGGEAP_00795 8.2e-113 S DNA binding
ICGGGEAP_00796 2e-09 S Domain of unknown function (DUF771)
ICGGGEAP_00797 2e-20
ICGGGEAP_00800 1.2e-17 ps115 K Helix-turn-helix XRE-family like proteins
ICGGGEAP_00801 6.4e-26 xkdA E Zn peptidase
ICGGGEAP_00803 3.3e-15 L nuclease
ICGGGEAP_00805 6e-116
ICGGGEAP_00807 9.8e-54
ICGGGEAP_00808 8.6e-81
ICGGGEAP_00810 1.8e-41 S Phage integrase family
ICGGGEAP_00811 1.3e-93 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICGGGEAP_00812 1e-156 P Belongs to the nlpA lipoprotein family
ICGGGEAP_00813 4.8e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICGGGEAP_00814 2.1e-115 S Protein of unknown function (DUF554)
ICGGGEAP_00815 3.1e-24 P Cadmium resistance transporter
ICGGGEAP_00816 4.7e-55 P Cadmium resistance transporter
ICGGGEAP_00817 4.8e-178 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICGGGEAP_00818 1.9e-217 iscS 2.8.1.7 E Aminotransferase class V
ICGGGEAP_00819 1e-52 C FMN binding
ICGGGEAP_00820 2.5e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICGGGEAP_00821 8.3e-108 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
ICGGGEAP_00822 1.7e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ICGGGEAP_00823 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ICGGGEAP_00824 4.2e-217 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_00825 6.6e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICGGGEAP_00826 4.3e-109 C aldo keto reductase
ICGGGEAP_00827 2.4e-110 3.1.3.73 G phosphoglycerate mutase
ICGGGEAP_00828 1.9e-09
ICGGGEAP_00829 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICGGGEAP_00830 1.8e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICGGGEAP_00831 1.2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
ICGGGEAP_00832 1.2e-54 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICGGGEAP_00833 8.9e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICGGGEAP_00834 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICGGGEAP_00835 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICGGGEAP_00836 2.6e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ICGGGEAP_00837 5e-211 EG GntP family permease
ICGGGEAP_00838 3.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICGGGEAP_00839 2e-211 iscS2 2.8.1.7 E Aminotransferase class V
ICGGGEAP_00840 4.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICGGGEAP_00841 1.8e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICGGGEAP_00842 1.6e-08
ICGGGEAP_00843 2.8e-146 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICGGGEAP_00844 5.3e-133 S Membrane
ICGGGEAP_00845 3.7e-75 4.4.1.5 E Glyoxalase
ICGGGEAP_00846 7.2e-83 yueI S Protein of unknown function (DUF1694)
ICGGGEAP_00847 4.9e-235 rarA L recombination factor protein RarA
ICGGGEAP_00849 6.8e-81 usp6 T universal stress protein
ICGGGEAP_00850 2.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ICGGGEAP_00851 9.8e-263 pepC 3.4.22.40 E Peptidase C1-like family
ICGGGEAP_00852 1.2e-93 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
ICGGGEAP_00853 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICGGGEAP_00854 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
ICGGGEAP_00855 1.9e-95 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ICGGGEAP_00856 8e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICGGGEAP_00857 2e-203 yacL S domain protein
ICGGGEAP_00858 2.8e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICGGGEAP_00859 2.3e-99 ywlG S Belongs to the UPF0340 family
ICGGGEAP_00860 3.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICGGGEAP_00861 1.2e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICGGGEAP_00862 1.3e-134 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICGGGEAP_00863 3.4e-103 sigH K Belongs to the sigma-70 factor family
ICGGGEAP_00864 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICGGGEAP_00865 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICGGGEAP_00866 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
ICGGGEAP_00867 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICGGGEAP_00868 1.7e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICGGGEAP_00869 9.5e-242 steT E amino acid
ICGGGEAP_00870 7.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICGGGEAP_00871 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICGGGEAP_00872 4.7e-252 yifK E Amino acid permease
ICGGGEAP_00874 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICGGGEAP_00875 1.4e-231 N Uncharacterized conserved protein (DUF2075)
ICGGGEAP_00876 4.1e-55 S SNARE associated Golgi protein
ICGGGEAP_00877 1.1e-77 ndk 2.7.4.6 F Belongs to the NDK family
ICGGGEAP_00878 1e-96 padR K Virulence activator alpha C-term
ICGGGEAP_00879 3.1e-83 padC Q Phenolic acid decarboxylase
ICGGGEAP_00881 6.2e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
ICGGGEAP_00883 1.4e-142 ET Bacterial periplasmic substrate-binding proteins
ICGGGEAP_00884 2.3e-158 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICGGGEAP_00885 4.8e-221 aadAT EK Aminotransferase, class I
ICGGGEAP_00886 4.9e-17
ICGGGEAP_00887 9.3e-171 S Beta-lactamase superfamily domain
ICGGGEAP_00888 4.2e-30 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICGGGEAP_00889 7.6e-183 S PTS system sugar-specific permease component
ICGGGEAP_00890 8.2e-39 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICGGGEAP_00891 6.6e-71 gntR K rpiR family
ICGGGEAP_00893 3.7e-265 pipD E Dipeptidase
ICGGGEAP_00894 2.9e-162 endA F DNA RNA non-specific endonuclease
ICGGGEAP_00895 2e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ICGGGEAP_00896 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICGGGEAP_00897 1e-151 S Alpha/beta hydrolase of unknown function (DUF915)
ICGGGEAP_00899 7.3e-225
ICGGGEAP_00900 1.2e-191 V Beta-lactamase
ICGGGEAP_00901 3.5e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ICGGGEAP_00902 9.1e-125 S membrane transporter protein
ICGGGEAP_00903 2e-176 S AI-2E family transporter
ICGGGEAP_00904 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
ICGGGEAP_00905 1.6e-157 rssA S Phospholipase, patatin family
ICGGGEAP_00906 4.1e-167 K LysR substrate binding domain
ICGGGEAP_00907 0.0 1.3.5.4 C FAD binding domain
ICGGGEAP_00908 3.2e-72 S Domain of unknown function (DUF4352)
ICGGGEAP_00909 4.9e-112 yicL EG EamA-like transporter family
ICGGGEAP_00910 7.8e-61
ICGGGEAP_00911 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICGGGEAP_00912 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ICGGGEAP_00913 7.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICGGGEAP_00914 1.6e-174 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICGGGEAP_00915 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICGGGEAP_00916 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICGGGEAP_00917 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICGGGEAP_00919 9.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ICGGGEAP_00920 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
ICGGGEAP_00921 5.4e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICGGGEAP_00922 3.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICGGGEAP_00923 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICGGGEAP_00924 3.1e-159 S Tetratricopeptide repeat
ICGGGEAP_00925 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICGGGEAP_00926 4.5e-255 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICGGGEAP_00927 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICGGGEAP_00928 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
ICGGGEAP_00929 3.1e-52 ywnB S NAD(P)H-binding
ICGGGEAP_00930 1.3e-54 ydgH S MMPL family
ICGGGEAP_00931 1.1e-262 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ICGGGEAP_00932 2.2e-96 V VanZ like family
ICGGGEAP_00933 9.8e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ICGGGEAP_00934 2.8e-60 yneR
ICGGGEAP_00935 2.2e-182 K Transcriptional regulator, LacI family
ICGGGEAP_00936 3.6e-228 gntT EG Gluconate
ICGGGEAP_00937 3.8e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICGGGEAP_00938 9e-170 mutR K Transcriptional activator, Rgg GadR MutR family
ICGGGEAP_00940 5.7e-53 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
ICGGGEAP_00942 4.2e-80 copY K Copper transport repressor CopY TcrY
ICGGGEAP_00943 3.3e-40
ICGGGEAP_00944 2.4e-167 GK ROK family
ICGGGEAP_00945 8.3e-128 1.14.12.17 C Oxidoreductase NAD-binding domain
ICGGGEAP_00946 1e-309 ubiB S ABC1 family
ICGGGEAP_00947 5.1e-104 wecD3 K Acetyltransferase (GNAT) family
ICGGGEAP_00948 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICGGGEAP_00949 1.2e-53 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICGGGEAP_00950 4.6e-52 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICGGGEAP_00952 7.3e-244 yxbA 6.3.1.12 S ATP-grasp enzyme
ICGGGEAP_00953 1.1e-161 EG EamA-like transporter family
ICGGGEAP_00954 2.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICGGGEAP_00955 3.9e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
ICGGGEAP_00956 9.6e-95 L Probable transposase
ICGGGEAP_00957 2.8e-64 L Resolvase, N-terminal domain
ICGGGEAP_00958 3.8e-97 S Pfam:DUF3816
ICGGGEAP_00959 7.3e-256 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICGGGEAP_00960 9.2e-109 pncA Q Isochorismatase family
ICGGGEAP_00961 8.7e-125 3.6.1.13, 3.6.1.55 F NUDIX domain
ICGGGEAP_00962 0.0 clpE O Belongs to the ClpA ClpB family
ICGGGEAP_00964 8e-39 ptsH G phosphocarrier protein HPR
ICGGGEAP_00965 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICGGGEAP_00966 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ICGGGEAP_00967 2.1e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
ICGGGEAP_00968 2.7e-180 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICGGGEAP_00969 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
ICGGGEAP_00970 1.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
ICGGGEAP_00971 3.7e-29
ICGGGEAP_00973 4.9e-07 S YSIRK type signal peptide
ICGGGEAP_00974 5e-235 kgtP EGP Sugar (and other) transporter
ICGGGEAP_00975 1.2e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
ICGGGEAP_00976 2.9e-152 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICGGGEAP_00977 2.8e-149 isdE P Periplasmic binding protein
ICGGGEAP_00978 1e-94 M Iron Transport-associated domain
ICGGGEAP_00979 2.6e-90 isdH M Iron Transport-associated domain
ICGGGEAP_00981 1.7e-54 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICGGGEAP_00982 2.1e-56 ydzE EG EamA-like transporter family
ICGGGEAP_00983 1.5e-90 P Cadmium resistance transporter
ICGGGEAP_00984 7.7e-97 C aldo keto reductase
ICGGGEAP_00985 6.4e-19 S Uncharacterized protein conserved in bacteria (DUF2255)
ICGGGEAP_00988 3.3e-83 C Aldo keto reductase
ICGGGEAP_00989 2.8e-30 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICGGGEAP_00990 1.9e-35 S Cyclophilin-like
ICGGGEAP_00991 8e-56 C Flavodoxin
ICGGGEAP_00992 7.7e-91 K Bacterial regulatory helix-turn-helix protein, lysR family
ICGGGEAP_00994 1.7e-133 manR K PRD domain
ICGGGEAP_00995 1.5e-18 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICGGGEAP_00996 2.6e-53 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICGGGEAP_00997 2.5e-39 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
ICGGGEAP_00998 1.4e-126 G Phosphotransferase System
ICGGGEAP_00999 1.1e-108 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
ICGGGEAP_01000 1.2e-131 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICGGGEAP_01001 6.1e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICGGGEAP_01002 2.8e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
ICGGGEAP_01003 3.7e-193 ulaA 2.7.1.194 S PTS system sugar-specific permease component
ICGGGEAP_01004 2e-259 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICGGGEAP_01005 7.8e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICGGGEAP_01006 2e-135 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
ICGGGEAP_01007 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICGGGEAP_01008 2.1e-244 glpT G Major Facilitator Superfamily
ICGGGEAP_01009 9.7e-130 qmcA O prohibitin homologues
ICGGGEAP_01011 3.1e-75 uspA T universal stress protein
ICGGGEAP_01012 1.8e-58
ICGGGEAP_01013 2.5e-19
ICGGGEAP_01014 1e-156
ICGGGEAP_01015 8.4e-75 K Transcriptional regulator
ICGGGEAP_01016 1.1e-183 D Alpha beta
ICGGGEAP_01017 3.9e-72 O OsmC-like protein
ICGGGEAP_01018 1.5e-191 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
ICGGGEAP_01019 0.0 yjcE P Sodium proton antiporter
ICGGGEAP_01020 2.1e-08 yvlA
ICGGGEAP_01021 2.4e-113 P Cobalt transport protein
ICGGGEAP_01022 2.8e-252 cbiO1 S ABC transporter, ATP-binding protein
ICGGGEAP_01023 2.3e-99 S ABC-type cobalt transport system, permease component
ICGGGEAP_01024 7.5e-180 iunH2 3.2.2.1 F nucleoside hydrolase
ICGGGEAP_01025 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
ICGGGEAP_01026 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
ICGGGEAP_01027 2.8e-32 copZ P Heavy-metal-associated domain
ICGGGEAP_01028 2.6e-100 dps P Belongs to the Dps family
ICGGGEAP_01029 1.6e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
ICGGGEAP_01030 3.2e-56
ICGGGEAP_01031 2.3e-14
ICGGGEAP_01032 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICGGGEAP_01033 3.6e-125 pgm3 G phosphoglycerate mutase family
ICGGGEAP_01034 1.3e-146 qorB 1.6.5.2 GM NmrA-like family
ICGGGEAP_01035 5.6e-96 L PFAM Integrase catalytic region
ICGGGEAP_01036 9.3e-229 pbuX F xanthine permease
ICGGGEAP_01037 1.8e-170 corA P CorA-like Mg2+ transporter protein
ICGGGEAP_01038 2.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICGGGEAP_01039 2.3e-142 terC P membrane
ICGGGEAP_01040 1e-56 trxA1 O Belongs to the thioredoxin family
ICGGGEAP_01041 6.5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICGGGEAP_01042 4.8e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
ICGGGEAP_01043 3.3e-183 fruR3 K Transcriptional regulator, LacI family
ICGGGEAP_01044 1.6e-137 pgi 5.3.1.9 G Belongs to the GPI family
ICGGGEAP_01045 2.5e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ICGGGEAP_01046 4.4e-164 mepA V MATE efflux family protein
ICGGGEAP_01047 8.5e-56 mepA V MATE efflux family protein
ICGGGEAP_01048 1.6e-224 amtB P ammonium transporter
ICGGGEAP_01049 9.3e-133 XK27_08845 S ABC transporter, ATP-binding protein
ICGGGEAP_01050 3.3e-137 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ICGGGEAP_01051 5e-179 ABC-SBP S ABC transporter
ICGGGEAP_01052 1.9e-289 S ABC transporter, ATP-binding protein
ICGGGEAP_01053 2.9e-204 nrnB S DHHA1 domain
ICGGGEAP_01054 1.3e-108 M ErfK YbiS YcfS YnhG
ICGGGEAP_01055 1.3e-75 nrdI F NrdI Flavodoxin like
ICGGGEAP_01056 3.7e-106 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
ICGGGEAP_01057 6.7e-181 1.17.4.1 F Ribonucleotide reductase, small chain
ICGGGEAP_01058 5e-267 S Uncharacterized protein conserved in bacteria (DUF2325)
ICGGGEAP_01059 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ICGGGEAP_01060 9.9e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
ICGGGEAP_01061 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICGGGEAP_01062 2.3e-206 yfnA E Amino Acid
ICGGGEAP_01063 3.8e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ICGGGEAP_01064 9.1e-104 gmk2 2.7.4.8 F Guanylate kinase
ICGGGEAP_01065 4e-83 zur P Belongs to the Fur family
ICGGGEAP_01067 9.1e-167
ICGGGEAP_01068 1.7e-185 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ICGGGEAP_01069 7.3e-92 K Transcriptional regulator (TetR family)
ICGGGEAP_01070 3.2e-204 V domain protein
ICGGGEAP_01071 4.4e-123 sirR K iron dependent repressor
ICGGGEAP_01072 1.1e-29 cspA K Cold shock protein
ICGGGEAP_01073 6.5e-82 thrE S Putative threonine/serine exporter
ICGGGEAP_01074 1.4e-28 thrE S Putative threonine/serine exporter
ICGGGEAP_01075 6.9e-81 S Threonine/Serine exporter, ThrE
ICGGGEAP_01076 2.2e-114 lssY 3.6.1.27 I phosphatase
ICGGGEAP_01077 1.2e-154 I alpha/beta hydrolase fold
ICGGGEAP_01079 9.6e-267 lysP E amino acid
ICGGGEAP_01080 2.3e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ICGGGEAP_01085 8.3e-89 IQ reductase
ICGGGEAP_01086 4.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ICGGGEAP_01087 3e-53 S ABC-type cobalt transport system, permease component
ICGGGEAP_01088 1.5e-70 thiW S Thiamine-precursor transporter protein (ThiW)
ICGGGEAP_01089 6.4e-55 rmeB K transcriptional regulator, MerR family
ICGGGEAP_01090 2.9e-111 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
ICGGGEAP_01092 1.9e-10 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ICGGGEAP_01093 6e-120 J 2'-5' RNA ligase superfamily
ICGGGEAP_01094 8.2e-131 XK27_07210 6.1.1.6 S B3 4 domain
ICGGGEAP_01095 1.1e-192 adhP 1.1.1.1 C alcohol dehydrogenase
ICGGGEAP_01096 7e-59 M repeat protein
ICGGGEAP_01097 2.8e-09
ICGGGEAP_01098 8.4e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ICGGGEAP_01099 1.6e-141 yueF S AI-2E family transporter
ICGGGEAP_01100 1e-163 ykoT GT2 M Glycosyl transferase family 2
ICGGGEAP_01101 8.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICGGGEAP_01102 3.7e-95 M transferase activity, transferring glycosyl groups
ICGGGEAP_01103 1.6e-102 glfT1 1.1.1.133 S Glycosyltransferase like family 2
ICGGGEAP_01104 3.1e-83 S Bacterial membrane protein, YfhO
ICGGGEAP_01105 2.6e-169 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICGGGEAP_01106 2.3e-63 gntR1 K Transcriptional regulator, GntR family
ICGGGEAP_01107 5.2e-156 V ABC transporter, ATP-binding protein
ICGGGEAP_01108 3e-13
ICGGGEAP_01124 1e-15 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ICGGGEAP_01125 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICGGGEAP_01126 2.6e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICGGGEAP_01127 3.8e-198 coiA 3.6.4.12 S Competence protein
ICGGGEAP_01128 3.9e-113 yjbH Q Thioredoxin
ICGGGEAP_01129 6.2e-117 yjbM 2.7.6.5 S RelA SpoT domain protein
ICGGGEAP_01130 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICGGGEAP_01131 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ICGGGEAP_01132 3.7e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ICGGGEAP_01133 1e-159 rrmA 2.1.1.187 H Methyltransferase
ICGGGEAP_01134 3.3e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICGGGEAP_01135 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ICGGGEAP_01136 1.6e-07 S Protein of unknown function (DUF4044)
ICGGGEAP_01137 1.1e-56
ICGGGEAP_01146 2.3e-24 K Bacterial regulatory proteins, tetR family
ICGGGEAP_01148 1.5e-141 ET Bacterial periplasmic substrate-binding proteins
ICGGGEAP_01149 4.5e-110 XK27_05795 P ABC transporter permease
ICGGGEAP_01150 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ICGGGEAP_01151 1.2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICGGGEAP_01152 1.9e-158 sufD O Uncharacterized protein family (UPF0051)
ICGGGEAP_01153 4.6e-236 F Permease
ICGGGEAP_01154 2.1e-199 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
ICGGGEAP_01155 4e-84 ykhA 3.1.2.20 I Thioesterase superfamily
ICGGGEAP_01156 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
ICGGGEAP_01157 1.1e-93 K Transcriptional regulator, TetR family
ICGGGEAP_01158 1.8e-34 S CRISPR-associated protein (Cas_Csn2)
ICGGGEAP_01159 8.4e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICGGGEAP_01160 6.6e-93 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICGGGEAP_01161 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ICGGGEAP_01162 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICGGGEAP_01163 6.2e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICGGGEAP_01164 2.7e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICGGGEAP_01165 5.6e-107 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICGGGEAP_01166 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICGGGEAP_01167 2.5e-69 psiE S Phosphate-starvation-inducible E
ICGGGEAP_01168 1.5e-37 V CAAX protease self-immunity
ICGGGEAP_01169 5.9e-22
ICGGGEAP_01170 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICGGGEAP_01171 2.6e-64 L nuclease
ICGGGEAP_01172 1.4e-153 F DNA/RNA non-specific endonuclease
ICGGGEAP_01173 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ICGGGEAP_01174 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICGGGEAP_01175 2.2e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICGGGEAP_01176 0.0 asnB 6.3.5.4 E Asparagine synthase
ICGGGEAP_01177 6.6e-220 lysP E amino acid
ICGGGEAP_01178 2.1e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICGGGEAP_01179 3.1e-93 K Helix-turn-helix domain, rpiR family
ICGGGEAP_01180 2.3e-27 GM Glycosyltransferase like family 2
ICGGGEAP_01181 9.4e-61 M Glycosyltransferase like family 2
ICGGGEAP_01182 1.1e-121 S Polysaccharide biosynthesis protein
ICGGGEAP_01183 5.5e-84 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ICGGGEAP_01184 1.6e-91 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
ICGGGEAP_01185 9.3e-107 4.2.1.46 GM Male sterility protein
ICGGGEAP_01186 6.3e-93 S Cupin superfamily (DUF985)
ICGGGEAP_01187 2.3e-122 K response regulator
ICGGGEAP_01188 8e-205 hpk31 2.7.13.3 T Histidine kinase
ICGGGEAP_01189 1.2e-201 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICGGGEAP_01190 5e-138 azlC E AzlC protein
ICGGGEAP_01191 9.9e-60 azlD S branched-chain amino acid
ICGGGEAP_01192 1.7e-100 L Belongs to the 'phage' integrase family
ICGGGEAP_01194 2e-85
ICGGGEAP_01195 1.7e-78 F Nucleoside 2-deoxyribosyltransferase
ICGGGEAP_01196 1.6e-180 scrR3 K Transcriptional regulator, LacI family
ICGGGEAP_01197 8e-12
ICGGGEAP_01198 5.7e-116 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ICGGGEAP_01199 0.0 asnB 6.3.5.4 E Aluminium induced protein
ICGGGEAP_01200 3.8e-50 S Sugar efflux transporter for intercellular exchange
ICGGGEAP_01201 8.9e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ICGGGEAP_01202 1.8e-41 S Protein conserved in bacteria
ICGGGEAP_01203 1.1e-95 ywrO S Flavodoxin-like fold
ICGGGEAP_01204 4e-150 tesE Q hydratase
ICGGGEAP_01205 1.5e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_01206 1.2e-61 S Domain of unknown function (DUF4440)
ICGGGEAP_01207 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICGGGEAP_01208 2.7e-244 fucP G Major Facilitator Superfamily
ICGGGEAP_01209 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICGGGEAP_01210 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICGGGEAP_01211 1.6e-169 deoR K sugar-binding domain protein
ICGGGEAP_01212 4.9e-114 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICGGGEAP_01213 5.8e-199 S Domain of unknown function (DUF4432)
ICGGGEAP_01214 1.2e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICGGGEAP_01215 1.7e-260 G PTS system Galactitol-specific IIC component
ICGGGEAP_01216 1.1e-169 K helix_turn _helix lactose operon repressor
ICGGGEAP_01218 4e-22
ICGGGEAP_01219 1.6e-247 cycA E Amino acid permease
ICGGGEAP_01220 2.1e-84 perR P Belongs to the Fur family
ICGGGEAP_01221 1.5e-248 EGP Major facilitator Superfamily
ICGGGEAP_01222 5.8e-97 tag 3.2.2.20 L glycosylase
ICGGGEAP_01223 5.9e-52
ICGGGEAP_01224 1.2e-208 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICGGGEAP_01225 1.1e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICGGGEAP_01226 8.4e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICGGGEAP_01227 7.8e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
ICGGGEAP_01228 4.3e-126 ycsG P Natural resistance-associated macrophage protein
ICGGGEAP_01229 7.5e-111 ycsF S LamB/YcsF family
ICGGGEAP_01230 4.5e-130 ycsI S Protein of unknown function (DUF1445)
ICGGGEAP_01231 4.7e-11 ycsF S LamB/YcsF family
ICGGGEAP_01232 7.1e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ICGGGEAP_01233 5.9e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICGGGEAP_01234 2.7e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
ICGGGEAP_01235 2.3e-133 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
ICGGGEAP_01236 1.9e-71 K helix_turn_helix, mercury resistance
ICGGGEAP_01237 4.2e-80 S Psort location Cytoplasmic, score
ICGGGEAP_01238 8.2e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
ICGGGEAP_01239 1.1e-92 wecD K Acetyltransferase (GNAT) family
ICGGGEAP_01240 7.1e-104 3.2.1.17 NU mannosyl-glycoprotein
ICGGGEAP_01241 5.1e-127 asnA 6.3.1.1 F aspartate--ammonia ligase
ICGGGEAP_01242 2.7e-15 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ICGGGEAP_01243 4.6e-16 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
ICGGGEAP_01244 2.5e-211 2.1.1.14 E methionine synthase, vitamin-B12 independent
ICGGGEAP_01245 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICGGGEAP_01246 1.9e-28 S Cytochrome B5
ICGGGEAP_01250 2.7e-250 lmrB EGP Major facilitator Superfamily
ICGGGEAP_01251 2.1e-94 K transcriptional regulator
ICGGGEAP_01252 3.6e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
ICGGGEAP_01253 0.0 L Helicase C-terminal domain protein
ICGGGEAP_01254 4.6e-54 S MazG-like family
ICGGGEAP_01255 2.6e-106 lssY 3.6.1.27 I Acid phosphatase homologues
ICGGGEAP_01256 1.2e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ICGGGEAP_01257 2.2e-96
ICGGGEAP_01258 7.1e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICGGGEAP_01259 7.7e-150 ponA V Beta-lactamase enzyme family
ICGGGEAP_01260 8.4e-263 yjeM E Amino Acid
ICGGGEAP_01262 1.1e-109
ICGGGEAP_01263 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ICGGGEAP_01264 7.1e-164 K LysR substrate binding domain
ICGGGEAP_01265 1.2e-61 GM NAD(P)H-binding
ICGGGEAP_01266 5.2e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
ICGGGEAP_01267 2.7e-293 scrB 3.2.1.26 GH32 G invertase
ICGGGEAP_01268 6.4e-177 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
ICGGGEAP_01269 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
ICGGGEAP_01270 1.5e-106 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICGGGEAP_01271 1e-08 nlhH_1 I acetylesterase activity
ICGGGEAP_01272 7e-21 nlhH_1 I Carboxylesterase family
ICGGGEAP_01273 8.1e-80 mleR K LysR family
ICGGGEAP_01274 9.4e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ICGGGEAP_01275 1.5e-41 XK27_09615 S reductase
ICGGGEAP_01276 1.1e-108 XK27_09615 S reductase
ICGGGEAP_01277 2.4e-91 XK27_09620 S NADPH-dependent FMN reductase
ICGGGEAP_01278 2.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICGGGEAP_01279 2.6e-213 frdC 1.3.5.4 C FAD binding domain
ICGGGEAP_01280 1.9e-224 yflS P Sodium:sulfate symporter transmembrane region
ICGGGEAP_01281 3.8e-162 mleR K LysR family transcriptional regulator
ICGGGEAP_01282 3.2e-253 yjjP S Putative threonine/serine exporter
ICGGGEAP_01283 6.7e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
ICGGGEAP_01284 1.6e-188 I Alpha beta
ICGGGEAP_01285 3.1e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
ICGGGEAP_01286 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICGGGEAP_01287 5.1e-167 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ICGGGEAP_01288 9.8e-310 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
ICGGGEAP_01289 3.5e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ICGGGEAP_01290 1.7e-204 araR K Transcriptional regulator
ICGGGEAP_01291 1.3e-246 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ICGGGEAP_01292 8.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ICGGGEAP_01293 1.7e-112 S Domain of unknown function (DUF4811)
ICGGGEAP_01294 2.8e-266 lmrB EGP Major facilitator Superfamily
ICGGGEAP_01295 4.3e-74 merR K MerR HTH family regulatory protein
ICGGGEAP_01296 5.2e-59
ICGGGEAP_01297 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICGGGEAP_01298 8.5e-213 S CAAX protease self-immunity
ICGGGEAP_01299 1e-30 elaA S GNAT family
ICGGGEAP_01300 3.8e-84 usp1 T Belongs to the universal stress protein A family
ICGGGEAP_01301 1.1e-108 S VIT family
ICGGGEAP_01302 4e-114 S membrane
ICGGGEAP_01303 8.6e-148 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
ICGGGEAP_01305 1.6e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ICGGGEAP_01306 5.5e-161 hipB K Helix-turn-helix
ICGGGEAP_01307 7.5e-58 yitW S Iron-sulfur cluster assembly protein
ICGGGEAP_01308 3.4e-214 narK P Major Facilitator Superfamily
ICGGGEAP_01309 2.3e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICGGGEAP_01310 2.4e-34 moaD 2.8.1.12 H ThiS family
ICGGGEAP_01311 5.8e-64 moaE 2.8.1.12 H MoaE protein
ICGGGEAP_01312 9.3e-56 S Flavodoxin
ICGGGEAP_01313 2.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICGGGEAP_01314 1.7e-117 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
ICGGGEAP_01315 5e-229 ndh 1.6.99.3 C NADH dehydrogenase
ICGGGEAP_01317 1.5e-55 S Domain of unknown function (DUF956)
ICGGGEAP_01318 5.9e-166 manN G system, mannose fructose sorbose family IID component
ICGGGEAP_01319 3.5e-122 manY G PTS system
ICGGGEAP_01320 1e-179 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
ICGGGEAP_01321 1.6e-179 yfeX P Peroxidase
ICGGGEAP_01322 1.6e-88 racA K Domain of unknown function (DUF1836)
ICGGGEAP_01323 8.1e-146 yitS S EDD domain protein, DegV family
ICGGGEAP_01324 9e-133 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICGGGEAP_01325 2.3e-162 K LysR substrate binding domain
ICGGGEAP_01326 3.5e-159 MA20_14895 S Conserved hypothetical protein 698
ICGGGEAP_01328 1.6e-41 S glycosyl transferase family 2
ICGGGEAP_01329 7.2e-68 MA20_43635 M Capsular polysaccharide synthesis protein
ICGGGEAP_01330 9.2e-67 M Domain of unknown function (DUF4422)
ICGGGEAP_01331 1.4e-82 GT4 G Glycosyl transferase 4-like
ICGGGEAP_01332 1.1e-86 capM M Bacterial sugar transferase
ICGGGEAP_01333 1.4e-141 ywqE 3.1.3.48 GM PHP domain protein
ICGGGEAP_01334 7.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
ICGGGEAP_01335 5.9e-127 epsB M biosynthesis protein
ICGGGEAP_01336 1e-158 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICGGGEAP_01337 2e-278 mntH P H( )-stimulated, divalent metal cation uptake system
ICGGGEAP_01338 9.3e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
ICGGGEAP_01339 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
ICGGGEAP_01340 1.5e-157 hrtB V ABC transporter permease
ICGGGEAP_01341 1.8e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ICGGGEAP_01342 7e-75 argR K Regulates arginine biosynthesis genes
ICGGGEAP_01343 2.6e-46 czrA K Transcriptional regulator, ArsR family
ICGGGEAP_01344 1.5e-164 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICGGGEAP_01345 2e-61
ICGGGEAP_01346 2.5e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICGGGEAP_01347 1.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICGGGEAP_01348 0.0 dnaK O Heat shock 70 kDa protein
ICGGGEAP_01349 7.8e-176 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICGGGEAP_01350 1.5e-96 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICGGGEAP_01351 1.2e-68 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICGGGEAP_01352 2.2e-120 Q Methyltransferase domain
ICGGGEAP_01353 3.6e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ICGGGEAP_01354 1e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
ICGGGEAP_01356 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICGGGEAP_01357 4.3e-258 guaD 3.5.4.3 F Amidohydrolase family
ICGGGEAP_01358 1.7e-174 tdh 1.1.1.14 C Zinc-binding dehydrogenase
ICGGGEAP_01359 6.6e-31 S Sugar efflux transporter for intercellular exchange
ICGGGEAP_01360 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
ICGGGEAP_01361 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICGGGEAP_01362 2.6e-42
ICGGGEAP_01363 5.8e-297 ytgP S Polysaccharide biosynthesis protein
ICGGGEAP_01364 5.3e-61 3.2.1.23 S Domain of unknown function DUF302
ICGGGEAP_01367 9.8e-77
ICGGGEAP_01368 0.0 trxB2 1.8.1.9 C Thioredoxin domain
ICGGGEAP_01369 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
ICGGGEAP_01370 5e-288 3.2.1.21 GH3 G hydrolase, family 3
ICGGGEAP_01371 1.2e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICGGGEAP_01372 2.3e-270 pepV 3.5.1.18 E dipeptidase PepV
ICGGGEAP_01373 2.1e-85 uspA T Belongs to the universal stress protein A family
ICGGGEAP_01374 2e-250 S Putative peptidoglycan binding domain
ICGGGEAP_01375 2e-160 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICGGGEAP_01376 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
ICGGGEAP_01377 3.6e-111
ICGGGEAP_01378 2.9e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
ICGGGEAP_01379 7.6e-118 S CAAX protease self-immunity
ICGGGEAP_01380 8.4e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICGGGEAP_01381 9.2e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
ICGGGEAP_01382 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
ICGGGEAP_01383 1.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICGGGEAP_01384 5.9e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
ICGGGEAP_01385 1e-199 folP 2.5.1.15 H dihydropteroate synthase
ICGGGEAP_01387 7.2e-35
ICGGGEAP_01389 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ICGGGEAP_01390 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICGGGEAP_01391 9.8e-56 yheA S Belongs to the UPF0342 family
ICGGGEAP_01392 2.8e-179 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICGGGEAP_01393 1.3e-147 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICGGGEAP_01395 1.5e-76 hit FG histidine triad
ICGGGEAP_01396 2.3e-133 ecsA V ABC transporter, ATP-binding protein
ICGGGEAP_01397 4.1e-204 ecsB U ABC transporter
ICGGGEAP_01398 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICGGGEAP_01399 3.3e-58 ytzB S Small secreted protein
ICGGGEAP_01400 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICGGGEAP_01401 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICGGGEAP_01402 1e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ICGGGEAP_01403 6.9e-114 ybhL S Belongs to the BI1 family
ICGGGEAP_01404 2.5e-138 aroD S Serine hydrolase (FSH1)
ICGGGEAP_01405 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICGGGEAP_01406 4.7e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICGGGEAP_01407 2.1e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICGGGEAP_01408 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICGGGEAP_01409 2.2e-246 dnaB L replication initiation and membrane attachment
ICGGGEAP_01410 6.2e-171 dnaI L Primosomal protein DnaI
ICGGGEAP_01411 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICGGGEAP_01412 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ICGGGEAP_01413 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICGGGEAP_01414 2.6e-36 yoaK S Protein of unknown function (DUF1275)
ICGGGEAP_01415 5.4e-95 yqeG S HAD phosphatase, family IIIA
ICGGGEAP_01416 4.2e-214 yqeH S Ribosome biogenesis GTPase YqeH
ICGGGEAP_01417 2.6e-49 yhbY J RNA-binding protein
ICGGGEAP_01418 6e-93 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICGGGEAP_01419 4.7e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ICGGGEAP_01420 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICGGGEAP_01421 5.7e-135 yqeM Q Methyltransferase
ICGGGEAP_01422 1.2e-213 ylbM S Belongs to the UPF0348 family
ICGGGEAP_01423 2.7e-97 yceD S Uncharacterized ACR, COG1399
ICGGGEAP_01424 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICGGGEAP_01425 1.6e-120 K response regulator
ICGGGEAP_01426 5.8e-280 arlS 2.7.13.3 T Histidine kinase
ICGGGEAP_01427 1.3e-230 V MatE
ICGGGEAP_01428 1.1e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ICGGGEAP_01429 1.4e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICGGGEAP_01430 1.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ICGGGEAP_01431 2.2e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICGGGEAP_01432 2.9e-90 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICGGGEAP_01433 3.2e-21 yodB K Transcriptional regulator, HxlR family
ICGGGEAP_01434 5.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICGGGEAP_01435 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICGGGEAP_01436 5.2e-116 udk 2.7.1.48 F Cytidine monophosphokinase
ICGGGEAP_01437 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICGGGEAP_01438 0.0 S membrane
ICGGGEAP_01439 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ICGGGEAP_01440 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICGGGEAP_01441 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICGGGEAP_01442 4.6e-106 gluP 3.4.21.105 S Peptidase, S54 family
ICGGGEAP_01443 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
ICGGGEAP_01444 1.7e-179 glk 2.7.1.2 G Glucokinase
ICGGGEAP_01445 1.5e-71 yqhL P Rhodanese-like protein
ICGGGEAP_01446 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
ICGGGEAP_01447 5.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICGGGEAP_01448 3.2e-261 glnA 6.3.1.2 E glutamine synthetase
ICGGGEAP_01449 4.7e-13
ICGGGEAP_01450 9.2e-148
ICGGGEAP_01451 1.6e-174
ICGGGEAP_01452 1.5e-92 dut S Protein conserved in bacteria
ICGGGEAP_01453 4.6e-149 S Phage integrase family
ICGGGEAP_01454 5.9e-51 K TRANSCRIPTIONal
ICGGGEAP_01455 2.9e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICGGGEAP_01456 9.6e-186 yegS 2.7.1.107 G Lipid kinase
ICGGGEAP_01457 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICGGGEAP_01458 1.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICGGGEAP_01459 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICGGGEAP_01460 1.8e-164 camS S sex pheromone
ICGGGEAP_01461 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICGGGEAP_01462 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ICGGGEAP_01463 2.5e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICGGGEAP_01464 8e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICGGGEAP_01465 2.9e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
ICGGGEAP_01466 1.7e-137 IQ reductase
ICGGGEAP_01467 4.7e-186 S interspecies interaction between organisms
ICGGGEAP_01468 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ICGGGEAP_01469 7.7e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICGGGEAP_01470 5.9e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICGGGEAP_01471 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICGGGEAP_01472 7e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICGGGEAP_01473 1.5e-147 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICGGGEAP_01474 3.1e-60 rplQ J Ribosomal protein L17
ICGGGEAP_01475 4.5e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICGGGEAP_01476 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICGGGEAP_01477 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICGGGEAP_01478 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ICGGGEAP_01479 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICGGGEAP_01480 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICGGGEAP_01481 3.4e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICGGGEAP_01482 2.1e-65 rplO J Binds to the 23S rRNA
ICGGGEAP_01483 2.5e-23 rpmD J Ribosomal protein L30
ICGGGEAP_01484 9.7e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICGGGEAP_01485 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICGGGEAP_01486 4.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICGGGEAP_01487 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICGGGEAP_01488 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICGGGEAP_01489 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICGGGEAP_01490 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICGGGEAP_01491 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICGGGEAP_01492 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICGGGEAP_01493 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
ICGGGEAP_01494 3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICGGGEAP_01495 3.5e-104 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICGGGEAP_01496 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICGGGEAP_01497 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICGGGEAP_01498 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICGGGEAP_01499 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICGGGEAP_01500 2e-104 rplD J Forms part of the polypeptide exit tunnel
ICGGGEAP_01501 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICGGGEAP_01502 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ICGGGEAP_01503 7e-65 yviA S Protein of unknown function (DUF421)
ICGGGEAP_01504 1.9e-29 S Protein of unknown function (DUF3290)
ICGGGEAP_01505 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICGGGEAP_01506 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICGGGEAP_01507 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICGGGEAP_01508 9.6e-33 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
ICGGGEAP_01509 1.2e-211 ykiI
ICGGGEAP_01510 3.6e-134 puuD S peptidase C26
ICGGGEAP_01511 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICGGGEAP_01512 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICGGGEAP_01513 1.4e-104 K Bacterial regulatory proteins, tetR family
ICGGGEAP_01514 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICGGGEAP_01515 4.8e-79 ctsR K Belongs to the CtsR family
ICGGGEAP_01517 7.6e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
ICGGGEAP_01518 2.1e-138 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
ICGGGEAP_01519 6.8e-132 G Glycosyl hydrolases family 8
ICGGGEAP_01520 2.9e-190 ydaM M Glycosyl transferase family group 2
ICGGGEAP_01522 5.5e-65
ICGGGEAP_01523 2.6e-134 ycsG P Natural resistance-associated macrophage protein
ICGGGEAP_01524 1.2e-203 EGP Major facilitator Superfamily
ICGGGEAP_01526 1.1e-111 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase
ICGGGEAP_01527 5.5e-243 ganB 3.2.1.89 G arabinogalactan
ICGGGEAP_01528 4.7e-29 S Domain of unknown function (DUF4767)
ICGGGEAP_01529 1.9e-44 S Tautomerase enzyme
ICGGGEAP_01530 3.6e-19 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
ICGGGEAP_01531 3.9e-119 pnb C nitroreductase
ICGGGEAP_01532 6.5e-81 S Alpha/beta hydrolase family
ICGGGEAP_01533 3e-93 glcU U sugar transport
ICGGGEAP_01534 2.5e-47 glcU U sugar transport
ICGGGEAP_01535 1.3e-250 yclK 2.7.13.3 T Histidine kinase
ICGGGEAP_01536 2.8e-131 K response regulator
ICGGGEAP_01537 2.5e-215 K DNA binding
ICGGGEAP_01538 5.9e-155 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
ICGGGEAP_01539 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ICGGGEAP_01540 1.7e-14 S Protein of unknown function (DUF4256)
ICGGGEAP_01541 1.2e-14
ICGGGEAP_01542 1.3e-11 S Transglycosylase associated protein
ICGGGEAP_01543 4.4e-76 S Asp23 family, cell envelope-related function
ICGGGEAP_01544 2.1e-22 S Small integral membrane protein (DUF2273)
ICGGGEAP_01545 1.8e-88
ICGGGEAP_01546 1.3e-38 L Transposase
ICGGGEAP_01547 4e-15 K helix_turn_helix multiple antibiotic resistance protein
ICGGGEAP_01548 5.3e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ICGGGEAP_01549 2.9e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ICGGGEAP_01550 4.2e-202 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICGGGEAP_01551 6.9e-259 lpdA 1.8.1.4 C Dehydrogenase
ICGGGEAP_01552 1.9e-194 lplA 6.3.1.20 H Lipoate-protein ligase
ICGGGEAP_01553 2.1e-213 E GDSL-like Lipase/Acylhydrolase family
ICGGGEAP_01554 1.4e-34 K LysR substrate binding domain protein
ICGGGEAP_01555 3e-23 K LysR substrate binding domain protein
ICGGGEAP_01556 1.6e-211 naiP EGP Major facilitator Superfamily
ICGGGEAP_01557 1.7e-249 yhdP S Transporter associated domain
ICGGGEAP_01558 1.1e-199 mdtG EGP Major facilitator Superfamily
ICGGGEAP_01559 5.7e-30 EGP Major facilitator Superfamily
ICGGGEAP_01560 7.6e-111 EGP Major facilitator Superfamily
ICGGGEAP_01561 2.2e-167 T Calcineurin-like phosphoesterase superfamily domain
ICGGGEAP_01562 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICGGGEAP_01563 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICGGGEAP_01564 3.8e-149 S Alpha/beta hydrolase of unknown function (DUF915)
ICGGGEAP_01565 1.1e-275 pipD E Dipeptidase
ICGGGEAP_01566 0.0 yjbQ P TrkA C-terminal domain protein
ICGGGEAP_01567 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ICGGGEAP_01568 7.4e-283 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICGGGEAP_01570 0.0 kup P Transport of potassium into the cell
ICGGGEAP_01571 8.1e-46
ICGGGEAP_01572 4.6e-13
ICGGGEAP_01573 0.0 S Bacterial membrane protein YfhO
ICGGGEAP_01575 1.9e-235 lmrB EGP Major facilitator Superfamily
ICGGGEAP_01576 1.7e-154 S Alpha beta hydrolase
ICGGGEAP_01577 5.5e-89 1.6.5.2 GM NAD(P)H-binding
ICGGGEAP_01578 8e-48 1.6.5.2 GM NAD(P)H-binding
ICGGGEAP_01579 4e-150 S Sucrose-6F-phosphate phosphohydrolase
ICGGGEAP_01581 5.8e-248 dtpT U amino acid peptide transporter
ICGGGEAP_01582 3.9e-210 ydiN G Major Facilitator Superfamily
ICGGGEAP_01583 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
ICGGGEAP_01584 4e-212 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICGGGEAP_01585 7.2e-103
ICGGGEAP_01586 3.9e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ICGGGEAP_01587 2.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
ICGGGEAP_01588 1.9e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICGGGEAP_01589 5.1e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
ICGGGEAP_01590 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_01591 4.8e-174 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICGGGEAP_01592 6.6e-154 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ICGGGEAP_01593 8.7e-23 S Virus attachment protein p12 family
ICGGGEAP_01594 2.5e-300 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ICGGGEAP_01595 1.2e-49 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ICGGGEAP_01596 3.9e-33 feoA P FeoA domain
ICGGGEAP_01597 2.5e-144 sufC O FeS assembly ATPase SufC
ICGGGEAP_01598 1.4e-234 sufD O FeS assembly protein SufD
ICGGGEAP_01599 7.3e-228 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICGGGEAP_01600 7.9e-82 nifU C SUF system FeS assembly protein, NifU family
ICGGGEAP_01601 5.5e-272 sufB O assembly protein SufB
ICGGGEAP_01603 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ICGGGEAP_01604 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICGGGEAP_01605 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICGGGEAP_01606 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICGGGEAP_01607 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICGGGEAP_01608 6.5e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICGGGEAP_01609 2.5e-86 yabR J RNA binding
ICGGGEAP_01610 1.5e-56 divIC D Septum formation initiator
ICGGGEAP_01611 1.6e-39 yabO J S4 domain protein
ICGGGEAP_01612 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICGGGEAP_01613 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICGGGEAP_01614 6.8e-113 S (CBS) domain
ICGGGEAP_01615 7.3e-56 L Toxic component of a toxin-antitoxin (TA) module
ICGGGEAP_01616 2.6e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICGGGEAP_01617 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICGGGEAP_01618 3e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICGGGEAP_01619 2.3e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICGGGEAP_01620 5.4e-156 htpX O Belongs to the peptidase M48B family
ICGGGEAP_01621 2.5e-87 lemA S LemA family
ICGGGEAP_01622 1.4e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICGGGEAP_01623 4.7e-123 srtA 3.4.22.70 M sortase family
ICGGGEAP_01624 4.6e-21 mdtG EGP Major facilitator Superfamily
ICGGGEAP_01625 2.7e-121 mdtG EGP Major facilitator Superfamily
ICGGGEAP_01626 1.7e-40 rpmE2 J Ribosomal protein L31
ICGGGEAP_01627 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICGGGEAP_01628 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICGGGEAP_01629 2.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICGGGEAP_01630 3.2e-74 ywiB S Domain of unknown function (DUF1934)
ICGGGEAP_01631 5.3e-264 ywfO S HD domain protein
ICGGGEAP_01632 3.8e-140 yxeH S hydrolase
ICGGGEAP_01633 2e-31
ICGGGEAP_01634 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICGGGEAP_01635 6.9e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICGGGEAP_01636 6.4e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ICGGGEAP_01637 3.2e-128 znuB U ABC 3 transport family
ICGGGEAP_01638 7.3e-92 fhuC P ABC transporter
ICGGGEAP_01639 9.3e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
ICGGGEAP_01640 6e-157 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICGGGEAP_01641 2.6e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICGGGEAP_01642 5.6e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICGGGEAP_01643 3.4e-146 tatD L hydrolase, TatD family
ICGGGEAP_01644 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICGGGEAP_01645 4e-161 yunF F Protein of unknown function DUF72
ICGGGEAP_01646 1.9e-209 norA EGP Major facilitator Superfamily
ICGGGEAP_01647 5.5e-124 cobB K SIR2 family
ICGGGEAP_01648 2.5e-186
ICGGGEAP_01649 4.7e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ICGGGEAP_01650 2.8e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICGGGEAP_01651 0.0 helD 3.6.4.12 L DNA helicase
ICGGGEAP_01652 2.2e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICGGGEAP_01653 9e-153 metQ_4 P Belongs to the nlpA lipoprotein family
ICGGGEAP_01655 2.8e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
ICGGGEAP_01656 2.3e-24 phaG GT1 I carboxylic ester hydrolase activity
ICGGGEAP_01657 1.8e-162 K Transcriptional regulator
ICGGGEAP_01658 7.5e-67 akr5f 1.1.1.346 S reductase
ICGGGEAP_01659 7.9e-27 akr5f 1.1.1.346 S reductase
ICGGGEAP_01660 2.1e-125 S Oxidoreductase, aldo keto reductase family protein
ICGGGEAP_01661 5.6e-26 S Hexapeptide repeat of succinyl-transferase
ICGGGEAP_01662 0.0 pepN 3.4.11.2 E aminopeptidase
ICGGGEAP_01663 8.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ICGGGEAP_01664 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
ICGGGEAP_01665 1.6e-134 E GDSL-like Lipase/Acylhydrolase family
ICGGGEAP_01666 8.8e-124 C nitroreductase
ICGGGEAP_01667 3.9e-173 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
ICGGGEAP_01668 2.1e-25 arcC 2.7.2.2 E Amino acid kinase family
ICGGGEAP_01669 2.2e-76 arcC 2.7.2.2 E Amino acid kinase family
ICGGGEAP_01670 9.4e-27 S Protein of unknown function (DUF2877)
ICGGGEAP_01671 1e-35 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
ICGGGEAP_01672 4.8e-166 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
ICGGGEAP_01673 2.3e-08 sucD 6.2.1.5 C CoA-ligase
ICGGGEAP_01674 4.6e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_01675 3.9e-134 L PFAM transposase, IS4 family protein
ICGGGEAP_01676 6.4e-38 EGP Major Facilitator Superfamily
ICGGGEAP_01677 9.2e-26 EGP Major Facilitator Superfamily
ICGGGEAP_01678 1.5e-26 EGP Major Facilitator Superfamily
ICGGGEAP_01681 7.2e-36 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ICGGGEAP_01682 9.4e-46 L Putative transposase of IS4/5 family (DUF4096)
ICGGGEAP_01683 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
ICGGGEAP_01684 0.0 comEC S Competence protein ComEC
ICGGGEAP_01685 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
ICGGGEAP_01686 3.8e-90 comEA L Competence protein ComEA
ICGGGEAP_01687 2.4e-195 ylbL T Belongs to the peptidase S16 family
ICGGGEAP_01688 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICGGGEAP_01689 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ICGGGEAP_01690 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ICGGGEAP_01691 8.7e-210 ftsW D Belongs to the SEDS family
ICGGGEAP_01692 0.0 typA T GTP-binding protein TypA
ICGGGEAP_01693 1.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ICGGGEAP_01694 1.2e-48 yktA S Belongs to the UPF0223 family
ICGGGEAP_01695 4.9e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICGGGEAP_01696 2e-74
ICGGGEAP_01697 2.2e-31 ykzG S Belongs to the UPF0356 family
ICGGGEAP_01698 5.8e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
ICGGGEAP_01699 4.2e-74 spx4 1.20.4.1 P ArsC family
ICGGGEAP_01700 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICGGGEAP_01701 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICGGGEAP_01702 6e-123 S Repeat protein
ICGGGEAP_01703 2e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ICGGGEAP_01704 8.9e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICGGGEAP_01705 1.6e-304 S amidohydrolase
ICGGGEAP_01706 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICGGGEAP_01707 7.6e-58 XK27_04120 S Putative amino acid metabolism
ICGGGEAP_01708 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICGGGEAP_01710 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ICGGGEAP_01711 1.2e-32 cspB K Cold shock protein
ICGGGEAP_01712 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICGGGEAP_01714 1.2e-99 divIVA D DivIVA domain protein
ICGGGEAP_01715 2.2e-145 ylmH S S4 domain protein
ICGGGEAP_01716 1.2e-40 yggT S YGGT family
ICGGGEAP_01717 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICGGGEAP_01718 8.7e-216 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICGGGEAP_01719 9.3e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICGGGEAP_01720 2.8e-146 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICGGGEAP_01721 3.4e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICGGGEAP_01722 1.2e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICGGGEAP_01723 5.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICGGGEAP_01724 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ICGGGEAP_01725 2e-08 ftsL D Cell division protein FtsL
ICGGGEAP_01726 9e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICGGGEAP_01727 9.6e-79 mraZ K Belongs to the MraZ family
ICGGGEAP_01728 2.1e-114 czcD P cation diffusion facilitator family transporter
ICGGGEAP_01729 9.4e-115 radC L DNA repair protein
ICGGGEAP_01730 1.9e-181 mreB D cell shape determining protein MreB
ICGGGEAP_01731 2.4e-145 mreC M Involved in formation and maintenance of cell shape
ICGGGEAP_01732 2.5e-92 mreD M rod shape-determining protein MreD
ICGGGEAP_01733 6.7e-108 glnP P ABC transporter permease
ICGGGEAP_01734 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICGGGEAP_01735 3.5e-160 aatB ET ABC transporter substrate-binding protein
ICGGGEAP_01736 2.6e-228 ymfF S Peptidase M16 inactive domain protein
ICGGGEAP_01737 2.4e-250 ymfH S Peptidase M16
ICGGGEAP_01738 3.2e-96 ymfM S Helix-turn-helix domain
ICGGGEAP_01739 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICGGGEAP_01740 1.1e-226 cinA 3.5.1.42 S Belongs to the CinA family
ICGGGEAP_01741 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICGGGEAP_01742 2.3e-202 rny S Endoribonuclease that initiates mRNA decay
ICGGGEAP_01743 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICGGGEAP_01744 5.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICGGGEAP_01745 5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICGGGEAP_01746 1.7e-173 2.4.2.29 F queuine tRNA-ribosyltransferase activity
ICGGGEAP_01747 9.3e-42 yajC U Preprotein translocase
ICGGGEAP_01748 2e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ICGGGEAP_01749 5.1e-230 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICGGGEAP_01750 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICGGGEAP_01751 1.2e-42 yrzL S Belongs to the UPF0297 family
ICGGGEAP_01752 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICGGGEAP_01753 5.7e-33 yrzB S Belongs to the UPF0473 family
ICGGGEAP_01754 4.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICGGGEAP_01755 1.4e-90 cvpA S Colicin V production protein
ICGGGEAP_01756 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICGGGEAP_01757 3.9e-53 trxA O Belongs to the thioredoxin family
ICGGGEAP_01758 3.8e-224 clcA_2 P Chloride transporter, ClC family
ICGGGEAP_01759 8.7e-93 yslB S Protein of unknown function (DUF2507)
ICGGGEAP_01760 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICGGGEAP_01761 1.5e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICGGGEAP_01762 8.8e-95 S Phosphoesterase
ICGGGEAP_01763 7.7e-147 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
ICGGGEAP_01764 5.8e-155 ykuT M mechanosensitive ion channel
ICGGGEAP_01765 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICGGGEAP_01766 1.7e-67
ICGGGEAP_01767 1e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICGGGEAP_01768 1e-182 ccpA K catabolite control protein A
ICGGGEAP_01769 4.5e-75
ICGGGEAP_01770 3.7e-134 yebC K Transcriptional regulatory protein
ICGGGEAP_01771 1.9e-80 mltD CBM50 M PFAM NLP P60 protein
ICGGGEAP_01772 2.4e-140 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
ICGGGEAP_01773 2.4e-175 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
ICGGGEAP_01774 8.6e-176 comGA NU Type II IV secretion system protein
ICGGGEAP_01775 2.5e-157 comGB NU type II secretion system
ICGGGEAP_01776 1.1e-47 comGC U competence protein ComGC
ICGGGEAP_01777 1.1e-14 NU general secretion pathway protein
ICGGGEAP_01779 1.3e-14
ICGGGEAP_01781 2.8e-157 ytxK 2.1.1.72 L N-6 DNA Methylase
ICGGGEAP_01782 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICGGGEAP_01783 6.1e-106 S Calcineurin-like phosphoesterase
ICGGGEAP_01784 5.6e-92 yutD S Protein of unknown function (DUF1027)
ICGGGEAP_01785 7.3e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICGGGEAP_01786 7.5e-25 S Protein of unknown function (DUF1461)
ICGGGEAP_01787 2.5e-102 dedA S SNARE-like domain protein
ICGGGEAP_01788 4.5e-73 L transposase, IS605 OrfB family
ICGGGEAP_01790 2.8e-205 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICGGGEAP_01791 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICGGGEAP_01792 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ICGGGEAP_01793 1.1e-186 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ICGGGEAP_01794 5.4e-155 recO L Involved in DNA repair and RecF pathway recombination
ICGGGEAP_01795 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICGGGEAP_01796 2.3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ICGGGEAP_01797 2.8e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICGGGEAP_01798 4.2e-178 phoH T phosphate starvation-inducible protein PhoH
ICGGGEAP_01799 2.1e-71 yqeY S YqeY-like protein
ICGGGEAP_01800 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ICGGGEAP_01801 1.8e-127 yfeJ 6.3.5.2 F glutamine amidotransferase
ICGGGEAP_01802 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICGGGEAP_01803 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
ICGGGEAP_01804 5.7e-194 6.3.1.20 H Lipoate-protein ligase
ICGGGEAP_01805 6.3e-146 lytH 3.5.1.28 M Ami_3
ICGGGEAP_01806 2.2e-167 yniA G Phosphotransferase enzyme family
ICGGGEAP_01807 8.3e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
ICGGGEAP_01808 1e-241 mmuP E amino acid
ICGGGEAP_01809 1.2e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ICGGGEAP_01810 9.5e-25 hom1 1.1.1.3 E Homoserine dehydrogenase
ICGGGEAP_01811 6.1e-169 hom1 1.1.1.3 E Homoserine dehydrogenase
ICGGGEAP_01812 3.7e-134 IQ KR domain
ICGGGEAP_01813 9.1e-153 cjaA ET ABC transporter substrate-binding protein
ICGGGEAP_01814 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICGGGEAP_01815 2e-91 P ABC transporter permease
ICGGGEAP_01816 2.3e-111 papP P ABC transporter, permease protein
ICGGGEAP_01818 1.2e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
ICGGGEAP_01819 1.8e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
ICGGGEAP_01820 3.3e-83 slyA K Transcriptional regulator
ICGGGEAP_01821 2.1e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICGGGEAP_01822 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICGGGEAP_01823 4.4e-58
ICGGGEAP_01824 5.7e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICGGGEAP_01825 3.2e-178 prmA J Ribosomal protein L11 methyltransferase
ICGGGEAP_01826 8e-54
ICGGGEAP_01828 2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICGGGEAP_01829 1.4e-92 S integral membrane protein
ICGGGEAP_01830 1e-75 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICGGGEAP_01831 1.5e-183 argE 3.5.1.16 E Acetylornithine deacetylase
ICGGGEAP_01832 2.8e-14 S Domain of unknown function DUF1829
ICGGGEAP_01833 1.6e-166 scrR K Transcriptional regulator, LacI family
ICGGGEAP_01834 9.5e-26
ICGGGEAP_01835 1.7e-100
ICGGGEAP_01836 2.3e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICGGGEAP_01837 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
ICGGGEAP_01838 1.3e-54
ICGGGEAP_01839 1.4e-124 yrkL S Flavodoxin-like fold
ICGGGEAP_01841 5.8e-64 yeaO S Protein of unknown function, DUF488
ICGGGEAP_01842 6.5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ICGGGEAP_01843 4.5e-200 3.1.3.1 S associated with various cellular activities
ICGGGEAP_01844 8.7e-210 S Putative metallopeptidase domain
ICGGGEAP_01845 1e-44
ICGGGEAP_01846 1.8e-229 pbuG S permease
ICGGGEAP_01847 0.0 pepO 3.4.24.71 O Peptidase family M13
ICGGGEAP_01848 5e-90 ymdB S Macro domain protein
ICGGGEAP_01849 5e-145 pnuC H nicotinamide mononucleotide transporter
ICGGGEAP_01850 7.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICGGGEAP_01851 7.6e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_01852 2e-52
ICGGGEAP_01853 1.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ICGGGEAP_01854 6.3e-120 tcyB U Binding-protein-dependent transport system inner membrane component
ICGGGEAP_01855 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICGGGEAP_01856 6.9e-36
ICGGGEAP_01857 1.8e-95 yxkA S Phosphatidylethanolamine-binding protein
ICGGGEAP_01858 3.9e-142 ptp3 3.1.3.48 T Tyrosine phosphatase family
ICGGGEAP_01859 2.4e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
ICGGGEAP_01860 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICGGGEAP_01861 1.9e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ICGGGEAP_01862 4.6e-180 galR K Transcriptional regulator
ICGGGEAP_01863 0.0 rafA 3.2.1.22 G alpha-galactosidase
ICGGGEAP_01864 2.1e-277 lacS G Transporter
ICGGGEAP_01865 2e-62 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICGGGEAP_01866 7.7e-42 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ICGGGEAP_01867 3.1e-124 S Membrane
ICGGGEAP_01868 3.2e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICGGGEAP_01869 0.0 pepF E oligoendopeptidase F
ICGGGEAP_01870 4.7e-177 K helix_turn _helix lactose operon repressor
ICGGGEAP_01871 3.1e-101 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICGGGEAP_01872 9.3e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICGGGEAP_01873 2.7e-60 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
ICGGGEAP_01874 4.8e-158 C C4-dicarboxylate transmembrane transporter activity
ICGGGEAP_01875 1.1e-77 K AsnC family
ICGGGEAP_01876 6.7e-81 uspA T universal stress protein
ICGGGEAP_01877 1.5e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICGGGEAP_01878 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICGGGEAP_01879 3.3e-206 yeaN P Transporter, major facilitator family protein
ICGGGEAP_01880 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
ICGGGEAP_01881 5.4e-83 nrdI F Belongs to the NrdI family
ICGGGEAP_01882 7.6e-250 yhdP S Transporter associated domain
ICGGGEAP_01883 3e-90 GM epimerase
ICGGGEAP_01884 2.4e-84 M1-874 K Domain of unknown function (DUF1836)
ICGGGEAP_01885 4.1e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
ICGGGEAP_01886 8.7e-265 pipD E Dipeptidase
ICGGGEAP_01887 2.7e-129
ICGGGEAP_01888 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICGGGEAP_01889 3.5e-129 gntR K UbiC transcription regulator-associated domain protein
ICGGGEAP_01890 6.3e-148 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
ICGGGEAP_01891 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)