ORF_ID e_value Gene_name EC_number CAZy COGs Description
NIFIFOHA_00001 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIFIFOHA_00002 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
NIFIFOHA_00003 7.5e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NIFIFOHA_00004 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIFIFOHA_00005 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NIFIFOHA_00006 3.1e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIFIFOHA_00007 9.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIFIFOHA_00008 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NIFIFOHA_00009 4.1e-53 KT PspC domain protein
NIFIFOHA_00010 1.3e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIFIFOHA_00011 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIFIFOHA_00012 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIFIFOHA_00013 4.7e-128 comFC S Competence protein
NIFIFOHA_00014 6.3e-254 comFA L Helicase C-terminal domain protein
NIFIFOHA_00015 1.1e-113 yvyE 3.4.13.9 S YigZ family
NIFIFOHA_00016 6.4e-38
NIFIFOHA_00017 0.0 ydaO E amino acid
NIFIFOHA_00018 1.4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIFIFOHA_00019 4.3e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIFIFOHA_00020 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIFIFOHA_00021 0.0 uup S ABC transporter, ATP-binding protein
NIFIFOHA_00022 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIFIFOHA_00023 3.6e-89 bioY S BioY family
NIFIFOHA_00024 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NIFIFOHA_00025 1e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NIFIFOHA_00026 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIFIFOHA_00027 7.1e-264 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NIFIFOHA_00028 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIFIFOHA_00029 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIFIFOHA_00030 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIFIFOHA_00031 2.7e-129 IQ reductase
NIFIFOHA_00032 1.1e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NIFIFOHA_00033 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIFIFOHA_00034 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIFIFOHA_00035 2.3e-75 marR K Transcriptional regulator, MarR family
NIFIFOHA_00036 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIFIFOHA_00038 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIFIFOHA_00039 1.3e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NIFIFOHA_00040 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NIFIFOHA_00041 7.6e-216 arcT 2.6.1.1 E Aminotransferase
NIFIFOHA_00042 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NIFIFOHA_00043 1.2e-258 E Arginine ornithine antiporter
NIFIFOHA_00044 8.2e-240 arcA 3.5.3.6 E Arginine
NIFIFOHA_00045 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NIFIFOHA_00046 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIFIFOHA_00047 8.8e-148 KT YcbB domain
NIFIFOHA_00048 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIFIFOHA_00049 6.7e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIFIFOHA_00050 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIFIFOHA_00051 4.8e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIFIFOHA_00052 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
NIFIFOHA_00053 2.7e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIFIFOHA_00054 1.5e-55 yabA L Involved in initiation control of chromosome replication
NIFIFOHA_00055 1.4e-192 holB 2.7.7.7 L DNA polymerase III
NIFIFOHA_00056 4e-53 yaaQ S Cyclic-di-AMP receptor
NIFIFOHA_00057 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIFIFOHA_00058 2.4e-21 S Protein of unknown function (DUF2508)
NIFIFOHA_00059 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIFIFOHA_00060 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIFIFOHA_00061 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIFIFOHA_00063 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIFIFOHA_00064 2e-35 nrdH O Glutaredoxin
NIFIFOHA_00065 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIFIFOHA_00066 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIFIFOHA_00067 4.1e-248 brnQ U Component of the transport system for branched-chain amino acids
NIFIFOHA_00068 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NIFIFOHA_00069 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIFIFOHA_00070 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIFIFOHA_00071 7.7e-175 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NIFIFOHA_00072 1.1e-272 cydA 1.10.3.14 C ubiquinol oxidase
NIFIFOHA_00073 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIFIFOHA_00074 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIFIFOHA_00075 4.6e-244 steT E amino acid
NIFIFOHA_00076 7.4e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIFIFOHA_00077 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIFIFOHA_00078 4.5e-97 nusG K Participates in transcription elongation, termination and antitermination
NIFIFOHA_00079 6.9e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIFIFOHA_00080 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIFIFOHA_00081 1.1e-104 sigH K Belongs to the sigma-70 factor family
NIFIFOHA_00082 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIFIFOHA_00083 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIFIFOHA_00084 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIFIFOHA_00085 7.8e-100 ywlG S Belongs to the UPF0340 family
NIFIFOHA_00086 6.2e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIFIFOHA_00087 9.4e-206 yacL S domain protein
NIFIFOHA_00088 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIFIFOHA_00089 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NIFIFOHA_00090 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
NIFIFOHA_00091 6.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIFIFOHA_00092 4e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
NIFIFOHA_00093 8.9e-264 pepC 3.4.22.40 E Peptidase C1-like family
NIFIFOHA_00094 1.5e-166 I alpha/beta hydrolase fold
NIFIFOHA_00095 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIFIFOHA_00096 2.3e-168 mleP2 S Sodium Bile acid symporter family
NIFIFOHA_00097 2e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NIFIFOHA_00098 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NIFIFOHA_00099 8.1e-84 ydcK S Belongs to the SprT family
NIFIFOHA_00100 0.0 yhgF K Tex-like protein N-terminal domain protein
NIFIFOHA_00101 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIFIFOHA_00102 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIFIFOHA_00103 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
NIFIFOHA_00104 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NIFIFOHA_00105 9.6e-115
NIFIFOHA_00107 2.8e-126 yjjH S Calcineurin-like phosphoesterase
NIFIFOHA_00108 6.9e-257 dtpT U amino acid peptide transporter
NIFIFOHA_00109 2.8e-169 D nuclear chromosome segregation
NIFIFOHA_00110 4.3e-144 L transposase, IS605 OrfB family
NIFIFOHA_00111 8.2e-216 S response to antibiotic
NIFIFOHA_00113 8.6e-11 S YjcQ protein
NIFIFOHA_00114 2.5e-147 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIFIFOHA_00115 5.3e-133 S Membrane
NIFIFOHA_00116 1.3e-75 4.4.1.5 E Glyoxalase
NIFIFOHA_00117 4.5e-85 yueI S Protein of unknown function (DUF1694)
NIFIFOHA_00118 5.8e-236 rarA L recombination factor protein RarA
NIFIFOHA_00120 2.3e-81 usp6 T universal stress protein
NIFIFOHA_00121 2.9e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NIFIFOHA_00122 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NIFIFOHA_00123 1.3e-254 G Major Facilitator Superfamily
NIFIFOHA_00124 1.3e-130 tnp L DDE domain
NIFIFOHA_00125 9.6e-234 yagE E Amino acid permease
NIFIFOHA_00126 8.3e-216 S Domain of unknown function (DUF389)
NIFIFOHA_00127 1.4e-53
NIFIFOHA_00128 1.5e-102 hrtB V ABC transporter permease
NIFIFOHA_00129 4.5e-115 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NIFIFOHA_00130 4.5e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NIFIFOHA_00132 1.6e-122 3.6.1.3 S AAA domain
NIFIFOHA_00133 2.3e-212 L Mu transposase, C-terminal
NIFIFOHA_00134 3.1e-85 tnpR2 L Resolvase, N terminal domain
NIFIFOHA_00137 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIFIFOHA_00138 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIFIFOHA_00139 1e-66 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIFIFOHA_00140 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
NIFIFOHA_00141 2.4e-311 ubiB S ABC1 family
NIFIFOHA_00142 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
NIFIFOHA_00143 1.7e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NIFIFOHA_00144 2.8e-177
NIFIFOHA_00145 6.5e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIFIFOHA_00146 5e-53 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIFIFOHA_00147 0.0 copA 3.6.3.54 P P-type ATPase
NIFIFOHA_00148 6e-26 EGP Major facilitator Superfamily
NIFIFOHA_00149 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
NIFIFOHA_00150 1.7e-13 dtpT U amino acid peptide transporter
NIFIFOHA_00151 2.5e-178 dtpT U amino acid peptide transporter
NIFIFOHA_00152 7.8e-110 GK ROK family
NIFIFOHA_00153 8.5e-50 copY K Copper transport repressor CopY TcrY
NIFIFOHA_00154 7.6e-11 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NIFIFOHA_00155 5.5e-96 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
NIFIFOHA_00156 2.6e-148 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIFIFOHA_00157 6.9e-123 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NIFIFOHA_00158 5.5e-225 aadAT EK Aminotransferase, class I
NIFIFOHA_00159 6.1e-159 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIFIFOHA_00160 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
NIFIFOHA_00161 8.9e-217 I transferase activity, transferring acyl groups other than amino-acyl groups
NIFIFOHA_00163 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIFIFOHA_00164 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIFIFOHA_00165 4.4e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIFIFOHA_00166 0.0 smc D Required for chromosome condensation and partitioning
NIFIFOHA_00167 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIFIFOHA_00168 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIFIFOHA_00169 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIFIFOHA_00170 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIFIFOHA_00171 2.9e-304 yloV S DAK2 domain fusion protein YloV
NIFIFOHA_00172 3.6e-58 asp S Asp23 family, cell envelope-related function
NIFIFOHA_00173 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NIFIFOHA_00174 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
NIFIFOHA_00175 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NIFIFOHA_00176 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIFIFOHA_00177 0.0 KLT serine threonine protein kinase
NIFIFOHA_00178 2.2e-131 stp 3.1.3.16 T phosphatase
NIFIFOHA_00179 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIFIFOHA_00180 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIFIFOHA_00181 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIFIFOHA_00182 2.7e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIFIFOHA_00183 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIFIFOHA_00184 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NIFIFOHA_00185 2.5e-15
NIFIFOHA_00186 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
NIFIFOHA_00187 2.3e-75 argR K Regulates arginine biosynthesis genes
NIFIFOHA_00188 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NIFIFOHA_00189 6.2e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIFIFOHA_00190 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIFIFOHA_00191 8.7e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIFIFOHA_00192 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIFIFOHA_00193 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIFIFOHA_00194 4.1e-72 yqhY S Asp23 family, cell envelope-related function
NIFIFOHA_00195 3.1e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIFIFOHA_00196 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NIFIFOHA_00197 9e-53 ysxB J Cysteine protease Prp
NIFIFOHA_00198 8.9e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NIFIFOHA_00199 2.8e-114 K Transcriptional regulator
NIFIFOHA_00201 1.8e-10
NIFIFOHA_00202 5.3e-27
NIFIFOHA_00203 6.9e-92 ps461 3.5.1.104 M hydrolase, family 25
NIFIFOHA_00204 6.8e-19 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NIFIFOHA_00208 2e-59
NIFIFOHA_00209 2.6e-27 S GDSL-like Lipase/Acylhydrolase
NIFIFOHA_00212 2.6e-58 spoIVFA GT2,GT4 D peptidase
NIFIFOHA_00213 6.9e-114 S Peptidase family M23
NIFIFOHA_00214 4.9e-151 S Phage tail protein
NIFIFOHA_00215 0.0 S peptidoglycan catabolic process
NIFIFOHA_00216 9.9e-14
NIFIFOHA_00217 1.7e-12
NIFIFOHA_00218 1.2e-111 S Pfam:Phage_TTP_1
NIFIFOHA_00219 4.5e-41
NIFIFOHA_00220 3.7e-37 S Bacteriophage HK97-gp10, putative tail-component
NIFIFOHA_00221 1.3e-30 S Phage head-tail joining protein
NIFIFOHA_00222 1.1e-44 S Phage gp6-like head-tail connector protein
NIFIFOHA_00223 4e-193 S peptidase activity
NIFIFOHA_00224 6e-40 pi136 S Caudovirus prohead serine protease
NIFIFOHA_00225 1.6e-238 S Phage portal protein
NIFIFOHA_00227 0.0 S Phage Terminase
NIFIFOHA_00228 1.1e-77 S Phage terminase, small subunit
NIFIFOHA_00229 5.6e-149 S HNH endonuclease
NIFIFOHA_00230 2.5e-154 S DNA metabolic process
NIFIFOHA_00233 1e-08 S Domain of unknown function (DUF771)
NIFIFOHA_00238 1.4e-144 K Phage regulatory protein
NIFIFOHA_00239 3.3e-47 3.4.21.88 K Helix-turn-helix domain
NIFIFOHA_00240 4.7e-67
NIFIFOHA_00241 7.6e-44 2.7.11.1 NU Domain of unknown function (DUF5067)
NIFIFOHA_00244 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NIFIFOHA_00245 4.5e-120 V Type I restriction modification DNA specificity domain
NIFIFOHA_00246 2.7e-73 IQ reductase
NIFIFOHA_00247 2e-240 treB G phosphotransferase system
NIFIFOHA_00248 1.5e-71 treR K UTRA
NIFIFOHA_00249 2.9e-240 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NIFIFOHA_00250 3.7e-221 iscS 2.8.1.7 E Aminotransferase class V
NIFIFOHA_00251 2.3e-16 S ABC-type transport system involved in multi-copper enzyme maturation permease component
NIFIFOHA_00252 2e-52 T Transcriptional regulatory protein, C terminal
NIFIFOHA_00253 5.2e-62 T His Kinase A (phosphoacceptor) domain
NIFIFOHA_00254 2.5e-54 C FMN binding
NIFIFOHA_00255 8.4e-37 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIFIFOHA_00256 2.8e-282 ysaB V FtsX-like permease family
NIFIFOHA_00257 7.1e-117 macB2 V ABC transporter, ATP-binding protein
NIFIFOHA_00258 3.7e-105 T Histidine kinase-like ATPases
NIFIFOHA_00259 5.6e-97 K response regulator
NIFIFOHA_00260 1.7e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIFIFOHA_00261 7e-155 tesE Q hydratase
NIFIFOHA_00262 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NIFIFOHA_00263 4.7e-48 L transposase, IS605 OrfB family
NIFIFOHA_00264 1e-38 mdt(A) EGP Major facilitator Superfamily
NIFIFOHA_00265 6.5e-75 K Copper transport repressor CopY TcrY
NIFIFOHA_00266 0.0 copB 3.6.3.4 P P-type ATPase
NIFIFOHA_00268 1.2e-196 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NIFIFOHA_00269 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NIFIFOHA_00270 1e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIFIFOHA_00271 9.3e-253 nox C NADH oxidase
NIFIFOHA_00272 1.2e-260 npr 1.11.1.1 C NADH oxidase
NIFIFOHA_00273 2e-58 S hydrolase
NIFIFOHA_00274 8.3e-254 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NIFIFOHA_00275 2.7e-239 cycA E Amino acid permease
NIFIFOHA_00276 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIFIFOHA_00277 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIFIFOHA_00278 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NIFIFOHA_00279 1.4e-186 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NIFIFOHA_00280 6.4e-156 recO L Involved in DNA repair and RecF pathway recombination
NIFIFOHA_00281 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIFIFOHA_00282 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NIFIFOHA_00283 5.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIFIFOHA_00284 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
NIFIFOHA_00285 4.6e-71 yqeY S YqeY-like protein
NIFIFOHA_00286 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NIFIFOHA_00287 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NIFIFOHA_00288 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIFIFOHA_00289 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
NIFIFOHA_00290 2.1e-196 6.3.1.20 H Lipoate-protein ligase
NIFIFOHA_00291 1.6e-174 lytH 3.5.1.28 M Ami_3
NIFIFOHA_00292 1.4e-169 yniA G Phosphotransferase enzyme family
NIFIFOHA_00293 3.9e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NIFIFOHA_00294 1.4e-246 mmuP E amino acid
NIFIFOHA_00295 3.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NIFIFOHA_00296 1.4e-212 hom1 1.1.1.3 E Homoserine dehydrogenase
NIFIFOHA_00298 2.7e-137 IQ KR domain
NIFIFOHA_00299 3.1e-153 cjaA ET ABC transporter substrate-binding protein
NIFIFOHA_00300 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIFIFOHA_00301 8.5e-114 P ABC transporter permease
NIFIFOHA_00302 5.4e-113 papP P ABC transporter, permease protein
NIFIFOHA_00304 3.2e-150 ET Bacterial periplasmic substrate-binding proteins
NIFIFOHA_00305 7.3e-108 yxeN U ABC transporter, permease protein
NIFIFOHA_00306 1.8e-71 P Binding-protein-dependent transport system inner membrane component
NIFIFOHA_00307 2.2e-134 tcyN 3.6.3.21 E ABC transporter
NIFIFOHA_00308 6.4e-198 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
NIFIFOHA_00310 6.2e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NIFIFOHA_00311 4.6e-219 metC1 2.5.1.48, 4.4.1.8 E cystathionine
NIFIFOHA_00312 1e-84 slyA K Transcriptional regulator
NIFIFOHA_00313 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIFIFOHA_00314 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIFIFOHA_00315 9.8e-58
NIFIFOHA_00316 2e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIFIFOHA_00317 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
NIFIFOHA_00318 1.2e-54
NIFIFOHA_00320 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIFIFOHA_00321 6e-39 S integral membrane protein
NIFIFOHA_00322 1.1e-40 S integral membrane protein
NIFIFOHA_00323 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIFIFOHA_00324 2.1e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIFIFOHA_00325 7.9e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIFIFOHA_00326 2.4e-113 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIFIFOHA_00327 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIFIFOHA_00328 4.2e-69 psiE S Phosphate-starvation-inducible E
NIFIFOHA_00329 1e-38 V CAAX protease self-immunity
NIFIFOHA_00330 1.9e-216 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NIFIFOHA_00331 1.6e-94 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
NIFIFOHA_00332 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
NIFIFOHA_00333 1.7e-159 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
NIFIFOHA_00334 3.5e-76 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NIFIFOHA_00335 2.3e-106 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NIFIFOHA_00336 3.6e-09 K LysR substrate binding domain
NIFIFOHA_00337 4.7e-09 S ChrR Cupin-like domain
NIFIFOHA_00338 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIFIFOHA_00339 1.9e-158 P Belongs to the nlpA lipoprotein family
NIFIFOHA_00340 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIFIFOHA_00341 3.2e-116 S Protein of unknown function (DUF554)
NIFIFOHA_00342 1.1e-101 P Cadmium resistance transporter
NIFIFOHA_00343 3e-75 gtcA S Teichoic acid glycosylation protein
NIFIFOHA_00344 1.2e-76 fld C Flavodoxin
NIFIFOHA_00345 5.9e-168 map 3.4.11.18 E Methionine Aminopeptidase
NIFIFOHA_00346 1.3e-279 XK27_08315 M Sulfatase
NIFIFOHA_00347 3.8e-16
NIFIFOHA_00348 6e-12 S Transglycosylase associated protein
NIFIFOHA_00349 1e-69 S Asp23 family, cell envelope-related function
NIFIFOHA_00350 1.3e-86
NIFIFOHA_00351 1.3e-38 L Transposase and inactivated derivatives
NIFIFOHA_00352 1.1e-153 L COG2801 Transposase and inactivated derivatives
NIFIFOHA_00353 3.6e-210 L Belongs to the 'phage' integrase family
NIFIFOHA_00354 7.3e-35
NIFIFOHA_00356 7.5e-67 S Domain of unknown function DUF1828
NIFIFOHA_00357 2.2e-26
NIFIFOHA_00358 4.8e-295 scrB 3.2.1.26 GH32 G invertase
NIFIFOHA_00359 1.6e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
NIFIFOHA_00362 3.1e-44 S Protein of unknown function with HXXEE motif
NIFIFOHA_00363 5.4e-11 K Bacterial regulatory proteins, tetR family
NIFIFOHA_00364 4.6e-25
NIFIFOHA_00365 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
NIFIFOHA_00366 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NIFIFOHA_00367 4.8e-66 kilA K BRO family, N-terminal domain
NIFIFOHA_00368 9e-10 S sequence-specific DNA binding
NIFIFOHA_00369 4.4e-64 3.4.21.88 K Peptidase S24-like
NIFIFOHA_00370 3.7e-13
NIFIFOHA_00371 1.4e-63 pglK S polysaccharide biosynthetic process
NIFIFOHA_00372 3e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIFIFOHA_00373 4.9e-52 ypaA S Protein of unknown function (DUF1304)
NIFIFOHA_00374 2.1e-26 D Alpha beta
NIFIFOHA_00376 8.2e-34 S Protein of unknown function (DUF1064)
NIFIFOHA_00377 4.4e-10 K Cro/C1-type HTH DNA-binding domain
NIFIFOHA_00379 7.8e-45 dnaC 3.4.21.53 L IstB-like ATP binding protein
NIFIFOHA_00382 7.4e-65 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NIFIFOHA_00383 2.1e-91 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIFIFOHA_00384 2e-25 yitW S Iron-sulfur cluster assembly protein
NIFIFOHA_00385 2.9e-08 Q Signal peptide protein, YSIRK family
NIFIFOHA_00386 7.3e-45 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NIFIFOHA_00387 8.5e-58 UW LPXTG-motif cell wall anchor domain protein
NIFIFOHA_00388 1.1e-43 UW LPXTG-motif cell wall anchor domain protein
NIFIFOHA_00389 1.7e-86 yrjD S LUD domain
NIFIFOHA_00390 1.3e-242 lutB C 4Fe-4S dicluster domain
NIFIFOHA_00391 1.6e-118 lutA C Cysteine-rich domain
NIFIFOHA_00392 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NIFIFOHA_00393 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIFIFOHA_00394 2.4e-37 ynzC S UPF0291 protein
NIFIFOHA_00395 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
NIFIFOHA_00396 3.3e-115 plsC 2.3.1.51 I Acyltransferase
NIFIFOHA_00397 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
NIFIFOHA_00398 5.1e-47 yazA L GIY-YIG catalytic domain protein
NIFIFOHA_00399 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
NIFIFOHA_00400 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIFIFOHA_00401 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NIFIFOHA_00402 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIFIFOHA_00403 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIFIFOHA_00404 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
NIFIFOHA_00405 4.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NIFIFOHA_00406 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIFIFOHA_00407 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIFIFOHA_00408 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
NIFIFOHA_00409 4.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NIFIFOHA_00410 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIFIFOHA_00411 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIFIFOHA_00412 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIFIFOHA_00413 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIFIFOHA_00414 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
NIFIFOHA_00415 3.7e-224 nusA K Participates in both transcription termination and antitermination
NIFIFOHA_00416 1.4e-47 ylxR K Protein of unknown function (DUF448)
NIFIFOHA_00417 3.2e-50 ylxQ J ribosomal protein
NIFIFOHA_00418 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIFIFOHA_00419 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIFIFOHA_00420 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIFIFOHA_00421 6e-185 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NIFIFOHA_00422 6.4e-249 EGP Major facilitator Superfamily
NIFIFOHA_00423 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIFIFOHA_00425 4.7e-09
NIFIFOHA_00428 2.1e-148 recT L RecT family
NIFIFOHA_00429 1e-82 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
NIFIFOHA_00430 2.8e-12 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIFIFOHA_00437 1.4e-07 K Bacterial regulatory proteins, tetR family
NIFIFOHA_00439 1e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
NIFIFOHA_00440 2.8e-292 norB EGP Major Facilitator
NIFIFOHA_00443 2.3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIFIFOHA_00444 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
NIFIFOHA_00445 2.3e-72 K helix_turn_helix, mercury resistance
NIFIFOHA_00446 1.7e-151 glcU U sugar transport
NIFIFOHA_00447 1.5e-251 yclK 2.7.13.3 T Histidine kinase
NIFIFOHA_00448 9.7e-132 K response regulator
NIFIFOHA_00450 2.7e-27 S Domain of unknown function (DUF956)
NIFIFOHA_00451 3e-170 manN G system, mannose fructose sorbose family IID component
NIFIFOHA_00452 2.7e-122 manY G PTS system
NIFIFOHA_00453 4.5e-180 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NIFIFOHA_00454 2.3e-181 yfeX P Peroxidase
NIFIFOHA_00455 2.5e-89 racA K Domain of unknown function (DUF1836)
NIFIFOHA_00456 1.1e-147 yitS S EDD domain protein, DegV family
NIFIFOHA_00457 3.8e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
NIFIFOHA_00458 2.8e-168 K LysR substrate binding domain
NIFIFOHA_00459 1.2e-156 MA20_14895 S Conserved hypothetical protein 698
NIFIFOHA_00460 2.4e-75 lytE M Lysin motif
NIFIFOHA_00461 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
NIFIFOHA_00462 7.1e-211 oatA I Acyltransferase
NIFIFOHA_00463 3.3e-52
NIFIFOHA_00464 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIFIFOHA_00465 6.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIFIFOHA_00466 9.1e-116 ybbR S YbbR-like protein
NIFIFOHA_00467 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIFIFOHA_00468 5.7e-166 murB 1.3.1.98 M Cell wall formation
NIFIFOHA_00469 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
NIFIFOHA_00470 7.3e-89 K Acetyltransferase (GNAT) domain
NIFIFOHA_00471 1.1e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NIFIFOHA_00472 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NIFIFOHA_00473 4e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIFIFOHA_00474 2.1e-108 yxjI
NIFIFOHA_00475 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIFIFOHA_00476 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIFIFOHA_00477 4.5e-33 secG U Preprotein translocase
NIFIFOHA_00478 1.9e-289 clcA P chloride
NIFIFOHA_00479 1.5e-253 yifK E Amino acid permease
NIFIFOHA_00480 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIFIFOHA_00481 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIFIFOHA_00482 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NIFIFOHA_00483 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIFIFOHA_00484 1e-15
NIFIFOHA_00485 3e-78
NIFIFOHA_00486 4.1e-110
NIFIFOHA_00487 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
NIFIFOHA_00488 5.9e-82 S Psort location Cytoplasmic, score
NIFIFOHA_00489 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NIFIFOHA_00490 1.1e-95 wecD K Acetyltransferase (GNAT) family
NIFIFOHA_00491 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
NIFIFOHA_00492 1.1e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
NIFIFOHA_00493 2.4e-35 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIFIFOHA_00494 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
NIFIFOHA_00495 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIFIFOHA_00496 3.5e-38 S Cytochrome B5
NIFIFOHA_00499 1.6e-15 S Domain of unknown function (DUF4811)
NIFIFOHA_00500 2.8e-255 lmrB EGP Major facilitator Superfamily
NIFIFOHA_00501 7.7e-97 K transcriptional regulator
NIFIFOHA_00502 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NIFIFOHA_00503 0.0 L Helicase C-terminal domain protein
NIFIFOHA_00504 1.6e-54 S MazG-like family
NIFIFOHA_00505 6.1e-108 lssY 3.6.1.27 I Acid phosphatase homologues
NIFIFOHA_00506 2.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NIFIFOHA_00507 2e-97
NIFIFOHA_00508 1e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIFIFOHA_00509 2.8e-168 ponA V Beta-lactamase enzyme family
NIFIFOHA_00510 6.2e-266 yjeM E Amino Acid
NIFIFOHA_00512 5.5e-112
NIFIFOHA_00513 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NIFIFOHA_00514 3.2e-164 K LysR substrate binding domain
NIFIFOHA_00515 1.4e-51 S Core-2/I-Branching enzyme
NIFIFOHA_00516 1.1e-195 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NIFIFOHA_00517 1.6e-54
NIFIFOHA_00518 9.4e-33 kcsA P Ion transport protein
NIFIFOHA_00519 8.6e-276 lacS G Transporter
NIFIFOHA_00520 0.0 rafA 3.2.1.22 G alpha-galactosidase
NIFIFOHA_00521 1.6e-180 galR K Transcriptional regulator
NIFIFOHA_00522 2.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NIFIFOHA_00523 1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIFIFOHA_00524 4.2e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NIFIFOHA_00525 3.5e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
NIFIFOHA_00526 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
NIFIFOHA_00527 6.9e-36
NIFIFOHA_00528 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIFIFOHA_00529 7.4e-121 tcyB U Binding-protein-dependent transport system inner membrane component
NIFIFOHA_00530 1.7e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NIFIFOHA_00531 2e-52
NIFIFOHA_00532 1.4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIFIFOHA_00533 6.4e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIFIFOHA_00534 6.9e-147 pnuC H nicotinamide mononucleotide transporter
NIFIFOHA_00535 2e-91 ymdB S Macro domain protein
NIFIFOHA_00536 0.0 pepO 3.4.24.71 O Peptidase family M13
NIFIFOHA_00537 1.8e-229 pbuG S permease
NIFIFOHA_00538 2.1e-45
NIFIFOHA_00539 7.6e-214 S Putative metallopeptidase domain
NIFIFOHA_00540 3.6e-205 3.1.3.1 S associated with various cellular activities
NIFIFOHA_00541 7.2e-115 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NIFIFOHA_00542 6.8e-65 yeaO S Protein of unknown function, DUF488
NIFIFOHA_00544 4.8e-125 yrkL S Flavodoxin-like fold
NIFIFOHA_00545 7.4e-55
NIFIFOHA_00546 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NIFIFOHA_00547 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIFIFOHA_00548 3.2e-102
NIFIFOHA_00549 9.5e-26
NIFIFOHA_00550 2.9e-168 scrR K Transcriptional regulator, LacI family
NIFIFOHA_00551 3.5e-174 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIFIFOHA_00552 2.6e-46 czrA K Transcriptional regulator, ArsR family
NIFIFOHA_00553 1.8e-75 argR K Regulates arginine biosynthesis genes
NIFIFOHA_00554 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NIFIFOHA_00555 1.3e-158 hrtB V ABC transporter permease
NIFIFOHA_00556 8.2e-108 ygfC K Bacterial regulatory proteins, tetR family
NIFIFOHA_00557 9.3e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NIFIFOHA_00558 4.2e-281 mntH P H( )-stimulated, divalent metal cation uptake system
NIFIFOHA_00559 6.5e-22
NIFIFOHA_00560 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIFIFOHA_00561 1.8e-70 L nuclease
NIFIFOHA_00562 5.8e-163 F DNA/RNA non-specific endonuclease
NIFIFOHA_00563 2.5e-75 L PFAM transposase, IS4 family protein
NIFIFOHA_00564 3.3e-138 ybeC E amino acid
NIFIFOHA_00565 7.3e-46
NIFIFOHA_00566 2.9e-62 K helix_turn_helix multiple antibiotic resistance protein
NIFIFOHA_00567 6.2e-134 ybeC E amino acid
NIFIFOHA_00568 1.3e-125 tnp L DDE domain
NIFIFOHA_00569 2.3e-150 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIFIFOHA_00570 4.2e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIFIFOHA_00571 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIFIFOHA_00572 1.3e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
NIFIFOHA_00573 5.5e-42 yajC U Preprotein translocase
NIFIFOHA_00574 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NIFIFOHA_00575 8.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIFIFOHA_00576 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIFIFOHA_00577 1.2e-42 yrzL S Belongs to the UPF0297 family
NIFIFOHA_00578 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIFIFOHA_00579 5.7e-33 yrzB S Belongs to the UPF0473 family
NIFIFOHA_00580 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIFIFOHA_00581 4.7e-91 cvpA S Colicin V production protein
NIFIFOHA_00582 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIFIFOHA_00583 1e-53 trxA O Belongs to the thioredoxin family
NIFIFOHA_00584 3.5e-225 clcA_2 P Chloride transporter, ClC family
NIFIFOHA_00585 7.2e-95 yslB S Protein of unknown function (DUF2507)
NIFIFOHA_00586 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIFIFOHA_00587 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIFIFOHA_00588 1.4e-95 S Phosphoesterase
NIFIFOHA_00589 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NIFIFOHA_00590 4e-156 ykuT M mechanosensitive ion channel
NIFIFOHA_00591 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIFIFOHA_00592 4.9e-70
NIFIFOHA_00593 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIFIFOHA_00594 2.2e-185 ccpA K catabolite control protein A
NIFIFOHA_00595 3.6e-85
NIFIFOHA_00596 3.7e-134 yebC K Transcriptional regulatory protein
NIFIFOHA_00597 4.6e-82 mltD CBM50 M PFAM NLP P60 protein
NIFIFOHA_00598 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
NIFIFOHA_00599 8.8e-136 comGA NU Type II IV secretion system protein
NIFIFOHA_00600 1.2e-32 comGA NU Type II IV secretion system protein
NIFIFOHA_00601 2.1e-159 comGB NU type II secretion system
NIFIFOHA_00602 1.1e-47 comGC U competence protein ComGC
NIFIFOHA_00603 2.3e-15 NU general secretion pathway protein
NIFIFOHA_00605 3.8e-14
NIFIFOHA_00607 4.6e-160 ytxK 2.1.1.72 L N-6 DNA Methylase
NIFIFOHA_00608 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIFIFOHA_00609 5.3e-110 S Calcineurin-like phosphoesterase
NIFIFOHA_00610 1.2e-97 yutD S Protein of unknown function (DUF1027)
NIFIFOHA_00611 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIFIFOHA_00612 9.8e-25 S Protein of unknown function (DUF1461)
NIFIFOHA_00613 3.5e-104 dedA S SNARE-like domain protein
NIFIFOHA_00615 6.4e-41 L Transposase, IS116 IS110 IS902 family
NIFIFOHA_00618 4.9e-13
NIFIFOHA_00619 8.4e-142 pgi 5.3.1.9 G Belongs to the GPI family
NIFIFOHA_00620 1.2e-74 L Transposase
NIFIFOHA_00621 3e-184 fruR3 K Transcriptional regulator, LacI family
NIFIFOHA_00622 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NIFIFOHA_00623 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIFIFOHA_00624 3e-56 trxA1 O Belongs to the thioredoxin family
NIFIFOHA_00625 2.6e-141 terC P membrane
NIFIFOHA_00626 1.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIFIFOHA_00627 9.7e-169 corA P CorA-like Mg2+ transporter protein
NIFIFOHA_00628 2.1e-228 pbuX F xanthine permease
NIFIFOHA_00629 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
NIFIFOHA_00630 2.5e-126 pgm3 G phosphoglycerate mutase family
NIFIFOHA_00631 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIFIFOHA_00632 2e-85
NIFIFOHA_00633 5.7e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NIFIFOHA_00634 1.2e-100 dps P Belongs to the Dps family
NIFIFOHA_00635 8.7e-34 copZ P Heavy-metal-associated domain
NIFIFOHA_00636 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NIFIFOHA_00637 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NIFIFOHA_00638 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
NIFIFOHA_00639 2.7e-100 S ABC-type cobalt transport system, permease component
NIFIFOHA_00640 9.2e-256 cbiO1 S ABC transporter, ATP-binding protein
NIFIFOHA_00641 1.8e-113 P Cobalt transport protein
NIFIFOHA_00642 3e-17 yvlA
NIFIFOHA_00643 0.0 yjcE P Sodium proton antiporter
NIFIFOHA_00644 6.9e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
NIFIFOHA_00645 7.8e-73 O OsmC-like protein
NIFIFOHA_00646 2.8e-187 D Alpha beta
NIFIFOHA_00647 8.4e-75 K Transcriptional regulator
NIFIFOHA_00648 4.5e-160
NIFIFOHA_00649 6.6e-20
NIFIFOHA_00650 2.1e-59
NIFIFOHA_00651 3.1e-75 uspA T universal stress protein
NIFIFOHA_00653 9.7e-130 qmcA O prohibitin homologues
NIFIFOHA_00654 5.5e-245 glpT G Major Facilitator Superfamily
NIFIFOHA_00655 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIFIFOHA_00656 3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NIFIFOHA_00657 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIFIFOHA_00658 6.3e-127 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIFIFOHA_00660 1.2e-36 rusA L Endodeoxyribonuclease RusA
NIFIFOHA_00663 5.1e-44 dnaC 3.4.21.53 L IstB-like ATP binding protein
NIFIFOHA_00664 5.7e-76 yphH S Cupin domain
NIFIFOHA_00666 3.5e-85 K GNAT family
NIFIFOHA_00667 8.9e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NIFIFOHA_00668 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
NIFIFOHA_00669 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIFIFOHA_00670 3.3e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NIFIFOHA_00672 3.6e-57
NIFIFOHA_00674 2.3e-07
NIFIFOHA_00675 4e-78 K Winged helix DNA-binding domain
NIFIFOHA_00676 0.0 lmrA V ABC transporter, ATP-binding protein
NIFIFOHA_00677 0.0 yfiC V ABC transporter
NIFIFOHA_00678 4.8e-193 ampC V Beta-lactamase
NIFIFOHA_00679 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIFIFOHA_00680 2.8e-48
NIFIFOHA_00681 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NIFIFOHA_00682 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NIFIFOHA_00683 3.2e-109 tdk 2.7.1.21 F thymidine kinase
NIFIFOHA_00684 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIFIFOHA_00685 1.3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIFIFOHA_00686 2.3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIFIFOHA_00687 5e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIFIFOHA_00688 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIFIFOHA_00689 1.7e-183 yibE S overlaps another CDS with the same product name
NIFIFOHA_00690 5.5e-125 yibF S overlaps another CDS with the same product name
NIFIFOHA_00691 5.4e-218 pyrP F Permease
NIFIFOHA_00692 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NIFIFOHA_00693 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIFIFOHA_00694 2.6e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIFIFOHA_00695 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIFIFOHA_00696 6.2e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIFIFOHA_00697 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIFIFOHA_00698 1.3e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIFIFOHA_00699 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NIFIFOHA_00700 2.8e-29 S Protein of unknown function (DUF1146)
NIFIFOHA_00701 1.8e-218 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
NIFIFOHA_00702 2.6e-183 mbl D Cell shape determining protein MreB Mrl
NIFIFOHA_00703 7.9e-32 S Protein of unknown function (DUF2969)
NIFIFOHA_00704 5.8e-222 rodA D Belongs to the SEDS family
NIFIFOHA_00706 5.3e-181 S Protein of unknown function (DUF2785)
NIFIFOHA_00707 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NIFIFOHA_00708 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIFIFOHA_00709 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIFIFOHA_00713 8.2e-31 S zinc-ribbon domain
NIFIFOHA_00714 1.1e-40
NIFIFOHA_00715 3.2e-36 M LysM domain
NIFIFOHA_00716 3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NIFIFOHA_00717 2.9e-211 EG GntP family permease
NIFIFOHA_00718 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIFIFOHA_00719 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
NIFIFOHA_00720 2.2e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIFIFOHA_00721 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIFIFOHA_00722 2e-68 V Abi-like protein
NIFIFOHA_00723 4.8e-131 M lysozyme activity
NIFIFOHA_00724 1e-20 S Bacteriophage holin family
NIFIFOHA_00727 9.2e-222 S peptidoglycan catabolic process
NIFIFOHA_00728 1.6e-63 S Phage tail protein
NIFIFOHA_00729 1.5e-165 S peptidoglycan catabolic process
NIFIFOHA_00730 2.2e-38 S Pfam:Phage_TAC_12
NIFIFOHA_00731 4e-83 S Phage major tail protein 2
NIFIFOHA_00732 1.2e-43
NIFIFOHA_00733 4.2e-42 S exonuclease activity
NIFIFOHA_00734 6.4e-19
NIFIFOHA_00735 7.2e-44 S Phage gp6-like head-tail connector protein
NIFIFOHA_00736 3.3e-118
NIFIFOHA_00737 2.3e-65 S aminoacyl-tRNA ligase activity
NIFIFOHA_00739 1.1e-136 S Phage Mu protein F like protein
NIFIFOHA_00740 1.4e-208 S Phage portal protein, SPP1 Gp6-like
NIFIFOHA_00741 1.2e-189 S Phage terminase, large subunit
NIFIFOHA_00743 1.1e-09 L Terminase small subunit
NIFIFOHA_00746 0.0 pepN 3.4.11.2 E aminopeptidase
NIFIFOHA_00747 3.5e-35 morA C Aldo keto reductase
NIFIFOHA_00748 9.3e-164 K Transcriptional regulator
NIFIFOHA_00749 3e-24 phaG GT1 I carboxylic ester hydrolase activity
NIFIFOHA_00750 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NIFIFOHA_00752 4.3e-155 metQ_4 P Belongs to the nlpA lipoprotein family
NIFIFOHA_00753 4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIFIFOHA_00754 0.0 helD 3.6.4.12 L DNA helicase
NIFIFOHA_00755 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIFIFOHA_00756 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NIFIFOHA_00757 2.2e-187
NIFIFOHA_00758 4.4e-129 cobB K SIR2 family
NIFIFOHA_00759 5.3e-212 norA EGP Major facilitator Superfamily
NIFIFOHA_00760 1.2e-162 yunF F Protein of unknown function DUF72
NIFIFOHA_00761 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIFIFOHA_00762 1.8e-147 tatD L hydrolase, TatD family
NIFIFOHA_00763 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIFIFOHA_00764 2.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIFIFOHA_00765 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIFIFOHA_00766 1.3e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
NIFIFOHA_00767 5.4e-95 fhuC P ABC transporter
NIFIFOHA_00768 3.2e-128 znuB U ABC 3 transport family
NIFIFOHA_00769 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NIFIFOHA_00770 1.3e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIFIFOHA_00771 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIFIFOHA_00772 3e-32
NIFIFOHA_00773 4.8e-143 yxeH S hydrolase
NIFIFOHA_00774 1.5e-266 ywfO S HD domain protein
NIFIFOHA_00775 3.2e-74 ywiB S Domain of unknown function (DUF1934)
NIFIFOHA_00776 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIFIFOHA_00777 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIFIFOHA_00778 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIFIFOHA_00779 6e-41 rpmE2 J Ribosomal protein L31
NIFIFOHA_00780 1.3e-49 mdtG EGP Major facilitator Superfamily
NIFIFOHA_00781 1.5e-55 mdtG EGP Major facilitator Superfamily
NIFIFOHA_00782 2.6e-144 arsB 1.20.4.1 P Sodium Bile acid symporter family
NIFIFOHA_00783 3.8e-56 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
NIFIFOHA_00784 1.1e-250 malT G Major Facilitator
NIFIFOHA_00785 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NIFIFOHA_00786 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NIFIFOHA_00787 1.1e-110 ysdA CP transmembrane transport
NIFIFOHA_00788 5.3e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIFIFOHA_00789 1.1e-46 D Alpha beta
NIFIFOHA_00790 8.7e-56 D Alpha beta
NIFIFOHA_00791 7.5e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIFIFOHA_00792 2.7e-216 patA 2.6.1.1 E Aminotransferase
NIFIFOHA_00793 1e-34
NIFIFOHA_00794 0.0 clpL O associated with various cellular activities
NIFIFOHA_00795 6.9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIFIFOHA_00796 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIFIFOHA_00797 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NIFIFOHA_00798 2.6e-163 yvgN C Aldo keto reductase
NIFIFOHA_00799 1.1e-289 glpQ 3.1.4.46 C phosphodiesterase
NIFIFOHA_00800 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
NIFIFOHA_00801 3.9e-188 ybhR V ABC transporter
NIFIFOHA_00802 3e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
NIFIFOHA_00803 4e-93 K transcriptional regulator
NIFIFOHA_00804 4.8e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIFIFOHA_00805 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIFIFOHA_00806 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NIFIFOHA_00807 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIFIFOHA_00808 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIFIFOHA_00809 8.5e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIFIFOHA_00810 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIFIFOHA_00811 1.2e-244 fucP G Major Facilitator Superfamily
NIFIFOHA_00812 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIFIFOHA_00813 7.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIFIFOHA_00814 1.4e-170 deoR K sugar-binding domain protein
NIFIFOHA_00815 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NIFIFOHA_00816 4e-200 S Domain of unknown function (DUF4432)
NIFIFOHA_00817 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIFIFOHA_00818 1.1e-259 G PTS system Galactitol-specific IIC component
NIFIFOHA_00819 4.7e-185 K helix_turn _helix lactose operon repressor
NIFIFOHA_00820 2.2e-279 yjeM E Amino Acid
NIFIFOHA_00822 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIFIFOHA_00823 1.1e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NIFIFOHA_00824 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
NIFIFOHA_00825 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIFIFOHA_00826 3.2e-130
NIFIFOHA_00827 1e-265 pipD E Dipeptidase
NIFIFOHA_00828 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NIFIFOHA_00829 8.9e-87 M1-874 K Domain of unknown function (DUF1836)
NIFIFOHA_00830 1.5e-89 GM epimerase
NIFIFOHA_00831 4e-251 yhdP S Transporter associated domain
NIFIFOHA_00832 2.4e-83 nrdI F Belongs to the NrdI family
NIFIFOHA_00833 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
NIFIFOHA_00834 2.8e-205 yeaN P Transporter, major facilitator family protein
NIFIFOHA_00835 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIFIFOHA_00836 5.8e-65 S module of peptide synthetase
NIFIFOHA_00837 1.5e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIFIFOHA_00838 7.4e-83 iolS C Aldo keto reductase
NIFIFOHA_00839 1.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIFIFOHA_00840 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIFIFOHA_00841 4.8e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
NIFIFOHA_00842 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIFIFOHA_00844 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIFIFOHA_00845 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NIFIFOHA_00846 2.1e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIFIFOHA_00847 3.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIFIFOHA_00849 3.7e-223 glnP P ABC transporter
NIFIFOHA_00850 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIFIFOHA_00851 6.4e-249 cycA E Amino acid permease
NIFIFOHA_00852 2.9e-213 nupG F Nucleoside transporter
NIFIFOHA_00853 2.2e-144 rihC 3.2.2.1 F Nucleoside
NIFIFOHA_00854 2e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NIFIFOHA_00855 8.4e-152 noc K Belongs to the ParB family
NIFIFOHA_00856 5.6e-147 spo0J K Belongs to the ParB family
NIFIFOHA_00857 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
NIFIFOHA_00858 2.8e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIFIFOHA_00859 4.2e-133 XK27_01040 S Protein of unknown function (DUF1129)
NIFIFOHA_00860 3.5e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIFIFOHA_00861 0.0 FbpA K Fibronectin-binding protein
NIFIFOHA_00862 3.2e-161 degV S EDD domain protein, DegV family
NIFIFOHA_00863 1.3e-97
NIFIFOHA_00864 4.8e-134 S Belongs to the UPF0246 family
NIFIFOHA_00865 9.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIFIFOHA_00866 5.3e-113 ylbE GM NAD(P)H-binding
NIFIFOHA_00867 3.5e-99 K Acetyltransferase (GNAT) domain
NIFIFOHA_00868 5.2e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIFIFOHA_00869 1.2e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NIFIFOHA_00870 1.6e-285 thrC 4.2.3.1 E Threonine synthase
NIFIFOHA_00871 1.8e-122 azlC E azaleucine resistance protein AzlC
NIFIFOHA_00872 2.8e-54 azlD E Branched-chain amino acid transport
NIFIFOHA_00873 4.8e-183 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NIFIFOHA_00874 1.3e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NIFIFOHA_00875 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIFIFOHA_00876 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
NIFIFOHA_00877 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NIFIFOHA_00878 1.5e-216 E GDSL-like Lipase/Acylhydrolase family
NIFIFOHA_00879 2.3e-33 K LysR substrate binding domain protein
NIFIFOHA_00880 4.6e-47 K LysR substrate binding domain protein
NIFIFOHA_00881 7.3e-212 naiP EGP Major facilitator Superfamily
NIFIFOHA_00882 1.2e-250 yhdP S Transporter associated domain
NIFIFOHA_00883 3.4e-201 mdtG EGP Major facilitator Superfamily
NIFIFOHA_00884 2.7e-159 EGP Major facilitator Superfamily
NIFIFOHA_00885 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
NIFIFOHA_00886 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIFIFOHA_00887 1.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIFIFOHA_00888 1.9e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NIFIFOHA_00889 4.8e-276 pipD E Dipeptidase
NIFIFOHA_00890 0.0 yjbQ P TrkA C-terminal domain protein
NIFIFOHA_00891 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NIFIFOHA_00892 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIFIFOHA_00894 0.0 kup P Transport of potassium into the cell
NIFIFOHA_00895 1.6e-49
NIFIFOHA_00896 0.0 S Bacterial membrane protein YfhO
NIFIFOHA_00898 2.7e-237 lmrB EGP Major facilitator Superfamily
NIFIFOHA_00899 6.7e-156 S Alpha beta hydrolase
NIFIFOHA_00900 1.2e-157 1.6.5.2 GM NAD(P)H-binding
NIFIFOHA_00901 1.1e-152 S Sucrose-6F-phosphate phosphohydrolase
NIFIFOHA_00902 4.8e-242 dtpT U amino acid peptide transporter
NIFIFOHA_00904 7.1e-212 ydiN G Major Facilitator Superfamily
NIFIFOHA_00905 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
NIFIFOHA_00906 6.7e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIFIFOHA_00907 1.4e-103
NIFIFOHA_00908 4.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NIFIFOHA_00909 6.9e-105 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NIFIFOHA_00910 2.8e-64 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NIFIFOHA_00911 3.3e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NIFIFOHA_00912 1e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
NIFIFOHA_00913 9.7e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIFIFOHA_00914 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIFIFOHA_00915 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NIFIFOHA_00916 1.5e-22 S Virus attachment protein p12 family
NIFIFOHA_00917 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NIFIFOHA_00918 3.9e-33 feoA P FeoA domain
NIFIFOHA_00919 9.4e-144 sufC O FeS assembly ATPase SufC
NIFIFOHA_00920 4.5e-244 sufD O FeS assembly protein SufD
NIFIFOHA_00921 4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIFIFOHA_00922 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
NIFIFOHA_00923 4.2e-272 sufB O assembly protein SufB
NIFIFOHA_00924 3.9e-177 fecB P Periplasmic binding protein
NIFIFOHA_00925 3.2e-142 EG EamA-like transporter family
NIFIFOHA_00926 9.5e-258 XK27_04775 S PAS domain
NIFIFOHA_00927 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
NIFIFOHA_00928 8e-54 yitW S Iron-sulfur cluster assembly protein
NIFIFOHA_00929 2.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
NIFIFOHA_00930 7.7e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NIFIFOHA_00931 3.3e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIFIFOHA_00932 2.2e-72 moaE 2.8.1.12 H MoaE protein
NIFIFOHA_00933 6.4e-35 moaD 2.8.1.12 H ThiS family
NIFIFOHA_00934 3.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIFIFOHA_00935 3.6e-216 narK P Major Facilitator Superfamily
NIFIFOHA_00936 1.5e-58 yitW S Iron-sulfur cluster assembly protein
NIFIFOHA_00937 4.5e-163 hipB K Helix-turn-helix
NIFIFOHA_00938 3.9e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIFIFOHA_00940 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NIFIFOHA_00941 3e-184
NIFIFOHA_00942 1.2e-39
NIFIFOHA_00943 3e-116 nreC K PFAM regulatory protein LuxR
NIFIFOHA_00944 7.9e-183 comP 2.7.13.3 F Sensor histidine kinase
NIFIFOHA_00945 1.4e-77 nreA T GAF domain
NIFIFOHA_00946 4.2e-40
NIFIFOHA_00947 1.1e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NIFIFOHA_00948 7.2e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NIFIFOHA_00949 1.5e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NIFIFOHA_00950 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NIFIFOHA_00951 2e-188 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NIFIFOHA_00952 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NIFIFOHA_00953 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
NIFIFOHA_00954 9.2e-102 narJ C Nitrate reductase delta subunit
NIFIFOHA_00955 8.7e-130 narI 1.7.5.1 C Nitrate reductase
NIFIFOHA_00956 1.3e-184
NIFIFOHA_00957 5.9e-76
NIFIFOHA_00958 7.2e-66 yjcE P Sodium proton antiporter
NIFIFOHA_00959 1.2e-48 ywnB S NAD(P)H-binding
NIFIFOHA_00960 3.4e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIFIFOHA_00961 2.2e-96 V VanZ like family
NIFIFOHA_00962 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NIFIFOHA_00963 2.5e-61 yneR
NIFIFOHA_00964 2.2e-182 K Transcriptional regulator, LacI family
NIFIFOHA_00965 3.2e-229 gntT EG Gluconate
NIFIFOHA_00966 1.2e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NIFIFOHA_00967 9.1e-107 mutR K Transcriptional activator, Rgg GadR MutR family
NIFIFOHA_00968 4.3e-50 mutR K Transcriptional activator, Rgg GadR MutR family
NIFIFOHA_00969 1.2e-11 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NIFIFOHA_00970 1.5e-46 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NIFIFOHA_00972 1.2e-79 copY K Copper transport repressor CopY TcrY
NIFIFOHA_00973 3.9e-41
NIFIFOHA_00974 2e-169 GK ROK family
NIFIFOHA_00975 2.9e-87 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIFIFOHA_00976 4.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NIFIFOHA_00977 1.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NIFIFOHA_00978 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NIFIFOHA_00979 2.1e-79 K 2 iron, 2 sulfur cluster binding
NIFIFOHA_00980 3.3e-266 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NIFIFOHA_00981 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIFIFOHA_00982 5.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NIFIFOHA_00983 3.2e-112 C aldo keto reductase
NIFIFOHA_00984 1.9e-112 3.1.3.73 G phosphoglycerate mutase
NIFIFOHA_00985 5.6e-09
NIFIFOHA_00986 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIFIFOHA_00987 5.1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIFIFOHA_00988 3.7e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NIFIFOHA_00989 8.5e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIFIFOHA_00990 1.9e-141 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIFIFOHA_00991 2.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NIFIFOHA_00992 1.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIFIFOHA_00993 1.9e-101 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NIFIFOHA_00994 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIFIFOHA_00995 5.8e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NIFIFOHA_00996 1.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NIFIFOHA_00997 8.9e-169 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
NIFIFOHA_00998 5e-51 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIFIFOHA_00999 2.9e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIFIFOHA_01000 2.4e-95 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIFIFOHA_01001 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIFIFOHA_01002 0.0 dnaK O Heat shock 70 kDa protein
NIFIFOHA_01003 4.9e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIFIFOHA_01004 5.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIFIFOHA_01005 2e-61
NIFIFOHA_01006 8e-274 nylA 3.5.1.4 J Belongs to the amidase family
NIFIFOHA_01007 6.2e-127 arcD S C4-dicarboxylate anaerobic carrier
NIFIFOHA_01008 8.5e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NIFIFOHA_01009 8.9e-83 F Hydrolase, NUDIX family
NIFIFOHA_01010 1.2e-211 S Type IV secretion-system coupling protein DNA-binding domain
NIFIFOHA_01011 0.0 tetP J elongation factor G
NIFIFOHA_01012 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIFIFOHA_01013 3.5e-111 ypsA S Belongs to the UPF0398 family
NIFIFOHA_01014 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIFIFOHA_01015 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NIFIFOHA_01016 3.7e-160 EG EamA-like transporter family
NIFIFOHA_01017 1.4e-192 C Aldo keto reductase family protein
NIFIFOHA_01018 3.7e-121 ypuA S Protein of unknown function (DUF1002)
NIFIFOHA_01019 4.7e-134 dnaD L DnaD domain protein
NIFIFOHA_01020 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NIFIFOHA_01021 1.6e-88 ypmB S Protein conserved in bacteria
NIFIFOHA_01022 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NIFIFOHA_01023 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NIFIFOHA_01024 8.2e-182 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NIFIFOHA_01025 3.3e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NIFIFOHA_01026 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIFIFOHA_01027 9e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NIFIFOHA_01028 2e-80 K FR47-like protein
NIFIFOHA_01029 7.8e-299 ybeC E amino acid
NIFIFOHA_01030 1.2e-134 pnuC H nicotinamide mononucleotide transporter
NIFIFOHA_01031 7.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NIFIFOHA_01032 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIFIFOHA_01033 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NIFIFOHA_01034 4e-116 dedA S SNARE associated Golgi protein
NIFIFOHA_01035 0.0 helD 3.6.4.12 L DNA helicase
NIFIFOHA_01036 2.5e-161 EG EamA-like transporter family
NIFIFOHA_01037 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIFIFOHA_01038 3.4e-135 IQ Dehydrogenase reductase
NIFIFOHA_01039 3.3e-82 2.3.1.128 K acetyltransferase
NIFIFOHA_01040 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
NIFIFOHA_01041 1.3e-131 sptS 2.7.13.3 T Histidine kinase
NIFIFOHA_01042 4e-79 K response regulator
NIFIFOHA_01043 1.1e-112 2.7.6.5 T Region found in RelA / SpoT proteins
NIFIFOHA_01044 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NIFIFOHA_01045 1.6e-85 S KAP family P-loop domain
NIFIFOHA_01046 9.2e-273 2.1.1.72 V type I restriction-modification system
NIFIFOHA_01048 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
NIFIFOHA_01049 1.3e-190 mocA S Oxidoreductase
NIFIFOHA_01050 4.9e-63 S Domain of unknown function (DUF4828)
NIFIFOHA_01051 5.2e-104 yvdD 3.2.2.10 S Belongs to the LOG family
NIFIFOHA_01052 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIFIFOHA_01053 6.2e-290 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIFIFOHA_01054 3.6e-140 S NADPH-dependent FMN reductase
NIFIFOHA_01055 2.3e-33 yneR S Belongs to the HesB IscA family
NIFIFOHA_01056 2.8e-304 ybiT S ABC transporter, ATP-binding protein
NIFIFOHA_01057 1.7e-84 dps P Belongs to the Dps family
NIFIFOHA_01058 6e-105
NIFIFOHA_01059 1.5e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIFIFOHA_01060 2.3e-101 K helix_turn_helix multiple antibiotic resistance protein
NIFIFOHA_01061 3.4e-49 fsr EGP Major Facilitator Superfamily
NIFIFOHA_01062 1.1e-78 fsr EGP Major Facilitator Superfamily
NIFIFOHA_01063 9.2e-100 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIFIFOHA_01064 7.8e-103 S CAAX protease self-immunity
NIFIFOHA_01066 4.1e-119 Q Methyltransferase domain
NIFIFOHA_01067 1.2e-60 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NIFIFOHA_01068 5.6e-20 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NIFIFOHA_01069 2.8e-51 K 2 iron, 2 sulfur cluster binding
NIFIFOHA_01070 0.0 mco Q Multicopper oxidase
NIFIFOHA_01071 7.1e-89 S Aminoacyl-tRNA editing domain
NIFIFOHA_01072 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
NIFIFOHA_01074 7e-195 nhaC C Na H antiporter NhaC
NIFIFOHA_01075 4.7e-123 srtA 3.4.22.70 M sortase family
NIFIFOHA_01076 3.1e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIFIFOHA_01077 1.9e-87 lemA S LemA family
NIFIFOHA_01078 4.9e-157 htpX O Belongs to the peptidase M48B family
NIFIFOHA_01079 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIFIFOHA_01080 6.6e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIFIFOHA_01081 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIFIFOHA_01082 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIFIFOHA_01083 5e-57 L Toxic component of a toxin-antitoxin (TA) module
NIFIFOHA_01084 8.1e-114 S (CBS) domain
NIFIFOHA_01085 8.2e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIFIFOHA_01086 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIFIFOHA_01087 1.6e-39 yabO J S4 domain protein
NIFIFOHA_01088 1.5e-56 divIC D Septum formation initiator
NIFIFOHA_01089 3e-87 yabR J RNA binding
NIFIFOHA_01090 9e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIFIFOHA_01091 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NIFIFOHA_01092 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIFIFOHA_01093 1.3e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIFIFOHA_01094 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIFIFOHA_01095 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NIFIFOHA_01096 2.4e-101 K DNA-templated transcription, initiation
NIFIFOHA_01098 0.0 N Uncharacterized conserved protein (DUF2075)
NIFIFOHA_01099 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NIFIFOHA_01100 2.8e-114 ybbL S ABC transporter, ATP-binding protein
NIFIFOHA_01101 8.5e-130 ybbM S Uncharacterised protein family (UPF0014)
NIFIFOHA_01102 7.2e-89 rmeB K transcriptional regulator, MerR family
NIFIFOHA_01103 4.9e-46 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
NIFIFOHA_01104 2.2e-113 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIFIFOHA_01105 1.7e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
NIFIFOHA_01107 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIFIFOHA_01108 3.9e-259 guaD 3.5.4.3 F Amidohydrolase family
NIFIFOHA_01109 1.9e-37 tdh 1.1.1.14 C Zinc-binding dehydrogenase
NIFIFOHA_01110 3.1e-96 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NIFIFOHA_01111 1.1e-30 S Sugar efflux transporter for intercellular exchange
NIFIFOHA_01112 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
NIFIFOHA_01113 3.8e-126 E Amino acid permease
NIFIFOHA_01114 4.7e-10 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NIFIFOHA_01115 5e-216 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NIFIFOHA_01117 9.9e-39 L Bacterial dnaA protein
NIFIFOHA_01118 9.2e-21 L transposase, IS605 OrfB family
NIFIFOHA_01119 8.7e-176 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIFIFOHA_01120 1.7e-97 S Pfam:DUF3816
NIFIFOHA_01121 1e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NIFIFOHA_01122 2.6e-99 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIFIFOHA_01123 6.5e-162 EG EamA-like transporter family
NIFIFOHA_01124 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
NIFIFOHA_01126 7.2e-15
NIFIFOHA_01127 1.6e-157 V ABC transporter, ATP-binding protein
NIFIFOHA_01128 7.8e-64 gntR1 K Transcriptional regulator, GntR family
NIFIFOHA_01129 6.8e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIFIFOHA_01130 1.1e-88 S Bacterial membrane protein, YfhO
NIFIFOHA_01131 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NIFIFOHA_01132 3.7e-95 M transferase activity, transferring glycosyl groups
NIFIFOHA_01133 7.7e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIFIFOHA_01134 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
NIFIFOHA_01135 6.7e-140 yueF S AI-2E family transporter
NIFIFOHA_01136 2.9e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NIFIFOHA_01137 2.1e-09
NIFIFOHA_01138 1.9e-63 M repeat protein
NIFIFOHA_01139 8.5e-60 3.2.1.96, 3.5.1.28 GH73 M repeat protein
NIFIFOHA_01140 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NIFIFOHA_01141 2.2e-27
NIFIFOHA_01142 3.1e-13
NIFIFOHA_01143 2.6e-236 kgtP EGP Sugar (and other) transporter
NIFIFOHA_01144 1.6e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
NIFIFOHA_01145 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIFIFOHA_01146 2.8e-149 isdE P Periplasmic binding protein
NIFIFOHA_01147 1e-94 M Iron Transport-associated domain
NIFIFOHA_01148 4.5e-274 isdH M Iron Transport-associated domain
NIFIFOHA_01149 4.3e-52
NIFIFOHA_01150 1.6e-52 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIFIFOHA_01151 1.5e-90 P Cadmium resistance transporter
NIFIFOHA_01155 8.1e-25 C Aldo keto reductase
NIFIFOHA_01156 2.2e-39 C Aldo keto reductase
NIFIFOHA_01157 4.1e-80 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIFIFOHA_01158 8.7e-104 S Alpha/beta hydrolase family
NIFIFOHA_01159 2e-120 pnb C nitroreductase
NIFIFOHA_01160 7e-28 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NIFIFOHA_01161 4.8e-17 S Tautomerase enzyme
NIFIFOHA_01162 6.1e-29 S Domain of unknown function (DUF4767)
NIFIFOHA_01165 1.3e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIFIFOHA_01166 7.8e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NIFIFOHA_01167 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NIFIFOHA_01168 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NIFIFOHA_01169 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIFIFOHA_01170 2.8e-137 cof S haloacid dehalogenase-like hydrolase
NIFIFOHA_01171 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIFIFOHA_01172 5.2e-113 yfbR S HD containing hydrolase-like enzyme
NIFIFOHA_01174 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIFIFOHA_01175 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIFIFOHA_01176 1.7e-204
NIFIFOHA_01177 3.9e-159 rapZ S Displays ATPase and GTPase activities
NIFIFOHA_01178 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NIFIFOHA_01179 1.9e-167 whiA K May be required for sporulation
NIFIFOHA_01180 3.4e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIFIFOHA_01181 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIFIFOHA_01185 1.5e-179 S Phosphotransferase system, EIIC
NIFIFOHA_01186 1.5e-21 D mRNA cleavage
NIFIFOHA_01187 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NIFIFOHA_01188 7.4e-112 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIFIFOHA_01189 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIFIFOHA_01190 3.8e-16
NIFIFOHA_01191 7.3e-64 yjbR S YjbR
NIFIFOHA_01192 6.1e-117 S Sel1-like repeats.
NIFIFOHA_01193 2.8e-89 K Psort location CytoplasmicMembrane, score
NIFIFOHA_01194 3.5e-82 K Helix-turn-helix XRE-family like proteins
NIFIFOHA_01195 2.2e-50 K TRANSCRIPTIONal
NIFIFOHA_01196 4.1e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIFIFOHA_01197 1.9e-186 yegS 2.7.1.107 G Lipid kinase
NIFIFOHA_01198 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIFIFOHA_01199 1.5e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIFIFOHA_01200 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIFIFOHA_01201 3.2e-166 camS S sex pheromone
NIFIFOHA_01202 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIFIFOHA_01203 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NIFIFOHA_01204 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIFIFOHA_01205 2.7e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIFIFOHA_01206 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NIFIFOHA_01207 1.2e-138 IQ reductase
NIFIFOHA_01208 6.4e-191 S interspecies interaction between organisms
NIFIFOHA_01209 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NIFIFOHA_01210 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIFIFOHA_01211 6.3e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIFIFOHA_01212 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIFIFOHA_01213 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIFIFOHA_01214 7.8e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIFIFOHA_01215 2.8e-61 rplQ J Ribosomal protein L17
NIFIFOHA_01216 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIFIFOHA_01217 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIFIFOHA_01218 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIFIFOHA_01219 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NIFIFOHA_01220 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIFIFOHA_01221 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIFIFOHA_01222 7.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIFIFOHA_01223 2.1e-65 rplO J Binds to the 23S rRNA
NIFIFOHA_01224 2.5e-23 rpmD J Ribosomal protein L30
NIFIFOHA_01225 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIFIFOHA_01226 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIFIFOHA_01227 1.9e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIFIFOHA_01228 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIFIFOHA_01229 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIFIFOHA_01230 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIFIFOHA_01231 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIFIFOHA_01232 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIFIFOHA_01233 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIFIFOHA_01234 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
NIFIFOHA_01235 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIFIFOHA_01236 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIFIFOHA_01237 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIFIFOHA_01238 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIFIFOHA_01239 1.6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIFIFOHA_01240 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIFIFOHA_01241 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
NIFIFOHA_01242 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIFIFOHA_01243 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NIFIFOHA_01244 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIFIFOHA_01245 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIFIFOHA_01246 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIFIFOHA_01247 1.6e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NIFIFOHA_01248 2.2e-213 ykiI
NIFIFOHA_01249 5.6e-135 puuD S peptidase C26
NIFIFOHA_01250 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIFIFOHA_01251 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIFIFOHA_01252 5.8e-106 K Bacterial regulatory proteins, tetR family
NIFIFOHA_01253 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIFIFOHA_01254 4.8e-79 ctsR K Belongs to the CtsR family
NIFIFOHA_01255 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
NIFIFOHA_01256 4.3e-132 XK27_07210 6.1.1.6 S B3 4 domain
NIFIFOHA_01257 7.9e-120 J 2'-5' RNA ligase superfamily
NIFIFOHA_01259 4.8e-42 S ABC-type cobalt transport system, permease component
NIFIFOHA_01260 1.9e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIFIFOHA_01261 1.3e-45 IQ reductase
NIFIFOHA_01262 1e-10 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIFIFOHA_01265 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NIFIFOHA_01266 3.9e-268 lysP E amino acid
NIFIFOHA_01268 1.4e-155 I alpha/beta hydrolase fold
NIFIFOHA_01269 1e-114 lssY 3.6.1.27 I phosphatase
NIFIFOHA_01270 2.8e-82 S Threonine/Serine exporter, ThrE
NIFIFOHA_01271 6.3e-126 thrE S Putative threonine/serine exporter
NIFIFOHA_01272 1.3e-30 cspA K Cold shock protein
NIFIFOHA_01273 1.2e-123 sirR K iron dependent repressor
NIFIFOHA_01274 1.3e-162 czcD P cation diffusion facilitator family transporter
NIFIFOHA_01275 2.5e-116 S membrane
NIFIFOHA_01276 5.8e-110 S VIT family
NIFIFOHA_01277 4.5e-85 usp1 T Belongs to the universal stress protein A family
NIFIFOHA_01278 8.1e-33 elaA S GNAT family
NIFIFOHA_01279 5.7e-217 S CAAX protease self-immunity
NIFIFOHA_01280 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIFIFOHA_01281 5.8e-58
NIFIFOHA_01282 5.6e-74 merR K MerR HTH family regulatory protein
NIFIFOHA_01283 6.6e-268 lmrB EGP Major facilitator Superfamily
NIFIFOHA_01284 4.4e-113 S Domain of unknown function (DUF4811)
NIFIFOHA_01285 3.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NIFIFOHA_01286 3.1e-248 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIFIFOHA_01287 6.4e-204 araR K Transcriptional regulator
NIFIFOHA_01288 1.2e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NIFIFOHA_01289 1.3e-309 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
NIFIFOHA_01290 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NIFIFOHA_01291 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIFIFOHA_01292 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NIFIFOHA_01293 1.6e-188 I Alpha beta
NIFIFOHA_01294 7.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NIFIFOHA_01295 2.1e-252 yjjP S Putative threonine/serine exporter
NIFIFOHA_01296 1.7e-162 mleR K LysR family transcriptional regulator
NIFIFOHA_01297 1.6e-223 yflS P Sodium:sulfate symporter transmembrane region
NIFIFOHA_01298 1e-214 frdC 1.3.5.4 C FAD binding domain
NIFIFOHA_01299 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIFIFOHA_01300 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
NIFIFOHA_01301 6e-183 XK27_09615 S reductase
NIFIFOHA_01302 3.6e-230 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NIFIFOHA_01303 5.3e-79 mleR K LysR family
NIFIFOHA_01304 1.3e-70 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIFIFOHA_01305 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIFIFOHA_01306 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
NIFIFOHA_01307 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIFIFOHA_01308 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
NIFIFOHA_01309 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIFIFOHA_01310 2e-95 ymfM S Helix-turn-helix domain
NIFIFOHA_01311 2.2e-251 ymfH S Peptidase M16
NIFIFOHA_01312 1.4e-229 ymfF S Peptidase M16 inactive domain protein
NIFIFOHA_01313 1.5e-160 aatB ET ABC transporter substrate-binding protein
NIFIFOHA_01314 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIFIFOHA_01315 1.4e-108 glnP P ABC transporter permease
NIFIFOHA_01316 6.6e-93 mreD M rod shape-determining protein MreD
NIFIFOHA_01317 3.7e-146 mreC M Involved in formation and maintenance of cell shape
NIFIFOHA_01318 1.9e-181 mreB D cell shape determining protein MreB
NIFIFOHA_01319 2.5e-115 radC L DNA repair protein
NIFIFOHA_01320 1e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIFIFOHA_01321 2.2e-99 padR K Virulence activator alpha C-term
NIFIFOHA_01322 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
NIFIFOHA_01323 5.3e-25 S SNARE associated Golgi protein
NIFIFOHA_01324 2.8e-13 S SNARE associated Golgi protein
NIFIFOHA_01325 7.8e-238 N Uncharacterized conserved protein (DUF2075)
NIFIFOHA_01326 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIFIFOHA_01328 1.1e-253 yifK E Amino acid permease
NIFIFOHA_01330 3.6e-39 pipD E Dipeptidase
NIFIFOHA_01331 1.5e-216 pipD E Dipeptidase
NIFIFOHA_01332 1.2e-163 endA F DNA RNA non-specific endonuclease
NIFIFOHA_01333 1.4e-164 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NIFIFOHA_01334 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIFIFOHA_01335 3.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
NIFIFOHA_01337 9.2e-228
NIFIFOHA_01338 2.6e-194 V Beta-lactamase
NIFIFOHA_01339 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NIFIFOHA_01340 5.5e-78 S membrane transporter protein
NIFIFOHA_01341 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NIFIFOHA_01342 8.6e-235 mepA V MATE efflux family protein
NIFIFOHA_01343 5.7e-225 amtB P ammonium transporter
NIFIFOHA_01345 1.2e-132 XK27_08845 S ABC transporter, ATP-binding protein
NIFIFOHA_01346 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NIFIFOHA_01347 5.9e-180 ABC-SBP S ABC transporter
NIFIFOHA_01348 4.9e-290 S ABC transporter, ATP-binding protein
NIFIFOHA_01349 8.9e-206 nrnB S DHHA1 domain
NIFIFOHA_01351 3e-110 M ErfK YbiS YcfS YnhG
NIFIFOHA_01352 1.4e-83 nrdI F NrdI Flavodoxin like
NIFIFOHA_01353 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIFIFOHA_01354 8.8e-170 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
NIFIFOHA_01355 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
NIFIFOHA_01356 1.7e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
NIFIFOHA_01357 3.2e-175 malR K Transcriptional regulator, LacI family
NIFIFOHA_01358 5.7e-71 K Transcriptional regulator
NIFIFOHA_01359 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIFIFOHA_01360 6.6e-208 htrA 3.4.21.107 O serine protease
NIFIFOHA_01361 7.8e-154 vicX 3.1.26.11 S domain protein
NIFIFOHA_01362 8e-143 yycI S YycH protein
NIFIFOHA_01363 3e-240 yycH S YycH protein
NIFIFOHA_01364 0.0 vicK 2.7.13.3 T Histidine kinase
NIFIFOHA_01365 6.8e-130 K response regulator
NIFIFOHA_01366 6.3e-50
NIFIFOHA_01367 2.2e-205 lmrP E Major Facilitator Superfamily
NIFIFOHA_01368 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NIFIFOHA_01369 1.2e-74 rplI J Binds to the 23S rRNA
NIFIFOHA_01370 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NIFIFOHA_01371 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIFIFOHA_01372 9.3e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIFIFOHA_01373 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NIFIFOHA_01374 9e-92 S Cupin superfamily (DUF985)
NIFIFOHA_01375 1.8e-122 K response regulator
NIFIFOHA_01376 7.7e-208 hpk31 2.7.13.3 T Histidine kinase
NIFIFOHA_01377 2.2e-203 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIFIFOHA_01378 1.2e-149 azlC E AzlC protein
NIFIFOHA_01379 8.9e-61 azlD S branched-chain amino acid
NIFIFOHA_01380 2.2e-99 ydeN S Serine hydrolase
NIFIFOHA_01381 6.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NIFIFOHA_01382 1.6e-11 K transcriptional regulator
NIFIFOHA_01383 6.9e-163 K AI-2E family transporter
NIFIFOHA_01384 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NIFIFOHA_01385 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIFIFOHA_01386 7.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIFIFOHA_01387 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIFIFOHA_01388 6.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
NIFIFOHA_01390 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NIFIFOHA_01391 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIFIFOHA_01392 2.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NIFIFOHA_01393 1.7e-117 ktrA P domain protein
NIFIFOHA_01394 6.7e-227 ktrB P Potassium uptake protein
NIFIFOHA_01395 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIFIFOHA_01396 6.5e-218 patA 2.6.1.1 E Aminotransferase
NIFIFOHA_01397 6.2e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIFIFOHA_01398 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIFIFOHA_01399 1.7e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIFIFOHA_01400 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIFIFOHA_01401 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIFIFOHA_01402 4.5e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
NIFIFOHA_01403 3.5e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIFIFOHA_01404 9.8e-77
NIFIFOHA_01405 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIFIFOHA_01406 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIFIFOHA_01407 9.6e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIFIFOHA_01408 2.2e-34 yaaA S S4 domain protein YaaA
NIFIFOHA_01409 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIFIFOHA_01410 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIFIFOHA_01411 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NIFIFOHA_01412 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIFIFOHA_01413 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIFIFOHA_01414 1.4e-153 jag S R3H domain protein
NIFIFOHA_01415 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIFIFOHA_01416 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIFIFOHA_01417 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NIFIFOHA_01418 1.4e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
NIFIFOHA_01419 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIFIFOHA_01420 4.4e-205 yfnA E Amino Acid
NIFIFOHA_01421 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NIFIFOHA_01422 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
NIFIFOHA_01423 1.2e-82 zur P Belongs to the Fur family
NIFIFOHA_01425 4.4e-169
NIFIFOHA_01426 1.1e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NIFIFOHA_01427 2.3e-93 K Transcriptional regulator (TetR family)
NIFIFOHA_01428 2.6e-206 V domain protein
NIFIFOHA_01429 8.6e-142 L An automated process has identified a potential problem with this gene model
NIFIFOHA_01430 9e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
NIFIFOHA_01432 2.5e-26 repA S Replication initiator protein A
NIFIFOHA_01433 3.2e-77 repA S Replication initiator protein A
NIFIFOHA_01434 3.1e-41 relB L Addiction module antitoxin, RelB DinJ family
NIFIFOHA_01435 1.1e-26
NIFIFOHA_01436 3.7e-117 S protein conserved in bacteria
NIFIFOHA_01437 1.4e-41
NIFIFOHA_01438 6.1e-26
NIFIFOHA_01439 0.0 L MobA MobL family protein
NIFIFOHA_01440 6.7e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NIFIFOHA_01441 4.5e-49 K DNA-binding transcription factor activity
NIFIFOHA_01442 1.1e-62 S SnoaL-like domain
NIFIFOHA_01443 1.4e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NIFIFOHA_01444 1.2e-154 yitU 3.1.3.104 S hydrolase
NIFIFOHA_01445 3.4e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIFIFOHA_01446 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIFIFOHA_01447 3.3e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIFIFOHA_01448 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIFIFOHA_01449 5.6e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NIFIFOHA_01450 4.5e-47 ycsI S Protein of unknown function (DUF1445)
NIFIFOHA_01451 6.3e-157 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NIFIFOHA_01452 7.5e-202 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NIFIFOHA_01453 4.5e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NIFIFOHA_01454 1e-27 XK27_02560 S Pfam:DUF59
NIFIFOHA_01455 2.6e-127 yocS S Transporter
NIFIFOHA_01456 1.9e-237 ydjE EGP Major facilitator Superfamily
NIFIFOHA_01457 8.1e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NIFIFOHA_01458 3.5e-279 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIFIFOHA_01459 1.1e-106 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NIFIFOHA_01460 6.7e-147 sua5 2.7.7.87 J Telomere recombination
NIFIFOHA_01462 5.6e-61 ybbM S Uncharacterised protein family (UPF0014)
NIFIFOHA_01464 4.8e-15 ydjK G Sugar (and other) transporter
NIFIFOHA_01465 4.6e-83 ydjK G Major Facilitator
NIFIFOHA_01467 1.7e-56 S Enoyl-(Acyl carrier protein) reductase
NIFIFOHA_01468 1.4e-27 IQ oxidoreductase activity
NIFIFOHA_01469 6.5e-50 C Flavodoxin
NIFIFOHA_01470 6.8e-51 yicL EG EamA-like transporter family
NIFIFOHA_01471 5.3e-78 yicL EG EamA-like transporter family
NIFIFOHA_01472 1.3e-105 L Integrase
NIFIFOHA_01473 3.3e-45 K transcriptional regulator
NIFIFOHA_01474 1.3e-108 GM NmrA-like family
NIFIFOHA_01475 3.9e-17 C Flavodoxin
NIFIFOHA_01476 2e-73 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NIFIFOHA_01477 4.2e-74 O OsmC-like protein
NIFIFOHA_01478 5.6e-77 K Transcriptional regulator
NIFIFOHA_01479 5.1e-162 proX M ABC transporter, substrate-binding protein, QAT family
NIFIFOHA_01480 1.8e-108 proWZ P ABC transporter permease
NIFIFOHA_01481 2.7e-140 proV E ABC transporter, ATP-binding protein
NIFIFOHA_01482 3.1e-102 proW P ABC transporter, permease protein
NIFIFOHA_01483 3.6e-151 C Zinc-binding dehydrogenase
NIFIFOHA_01484 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
NIFIFOHA_01485 1.9e-225 4.4.1.8 E Aminotransferase, class I
NIFIFOHA_01486 1.2e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIFIFOHA_01487 3.2e-203 xerS L Belongs to the 'phage' integrase family
NIFIFOHA_01488 4e-62 ywkB S Membrane transport protein
NIFIFOHA_01489 4.4e-180 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
NIFIFOHA_01490 1.4e-37 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
NIFIFOHA_01491 8.3e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NIFIFOHA_01492 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
NIFIFOHA_01493 1e-167 1.1.1.346 C Aldo keto reductase
NIFIFOHA_01494 1.5e-161 S DUF218 domain
NIFIFOHA_01496 1.3e-96 K Acetyltransferase (GNAT) domain
NIFIFOHA_01497 5.1e-164 I alpha/beta hydrolase fold
NIFIFOHA_01498 1.4e-60 S Phage minor capsid protein 2
NIFIFOHA_01499 8.9e-35 S Phage minor capsid protein 2
NIFIFOHA_01501 1.1e-55 2.6.1.1 E Aminotransferase
NIFIFOHA_01502 2.9e-145 2.6.1.1 E Aminotransferase
NIFIFOHA_01503 1.3e-180 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NIFIFOHA_01504 2.7e-247 EGP Sugar (and other) transporter
NIFIFOHA_01505 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
NIFIFOHA_01506 1.3e-90 S Fic/DOC family
NIFIFOHA_01507 6.7e-35 yncA 2.3.1.79 S Maltose acetyltransferase
NIFIFOHA_01508 4.3e-09 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIFIFOHA_01509 5.3e-105 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIFIFOHA_01510 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NIFIFOHA_01511 5.4e-262 arcD E Amino acid permease
NIFIFOHA_01512 1.4e-117 5.1.1.13 M racemase activity, acting on amino acids and derivatives
NIFIFOHA_01513 7.9e-158 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
NIFIFOHA_01514 7.3e-28 clcA P chloride
NIFIFOHA_01515 4.3e-66 clcA P chloride
NIFIFOHA_01516 7.2e-17 lmrB EGP Major facilitator Superfamily
NIFIFOHA_01518 2.9e-246 yhjX P Major Facilitator Superfamily
NIFIFOHA_01519 4.7e-120 S Protein of unknown function (DUF554)
NIFIFOHA_01520 2.8e-257 rarA L recombination factor protein RarA
NIFIFOHA_01522 0.0 oppD EP Psort location Cytoplasmic, score
NIFIFOHA_01523 8e-243 codA 3.5.4.1 F cytosine deaminase
NIFIFOHA_01524 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
NIFIFOHA_01525 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
NIFIFOHA_01526 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NIFIFOHA_01527 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NIFIFOHA_01528 2.3e-71 yqkB S Belongs to the HesB IscA family
NIFIFOHA_01529 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
NIFIFOHA_01530 5.2e-95 S Protein of unknown function (DUF1440)
NIFIFOHA_01531 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIFIFOHA_01532 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIFIFOHA_01533 8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIFIFOHA_01534 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
NIFIFOHA_01535 3.6e-154 D DNA integration
NIFIFOHA_01536 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIFIFOHA_01537 8.1e-165 dprA LU DNA protecting protein DprA
NIFIFOHA_01538 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIFIFOHA_01539 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIFIFOHA_01540 3.1e-36 yozE S Belongs to the UPF0346 family
NIFIFOHA_01541 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NIFIFOHA_01542 1.1e-167 ypmR E lipolytic protein G-D-S-L family
NIFIFOHA_01543 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
NIFIFOHA_01544 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
NIFIFOHA_01545 1.8e-153 DegV S EDD domain protein, DegV family
NIFIFOHA_01546 1.2e-109 hlyIII S protein, hemolysin III
NIFIFOHA_01547 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIFIFOHA_01548 8e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIFIFOHA_01549 0.0 yfmR S ABC transporter, ATP-binding protein
NIFIFOHA_01550 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIFIFOHA_01551 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
NIFIFOHA_01552 6.9e-234 S Tetratricopeptide repeat protein
NIFIFOHA_01553 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIFIFOHA_01554 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NIFIFOHA_01555 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
NIFIFOHA_01556 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NIFIFOHA_01557 9.7e-31 M Lysin motif
NIFIFOHA_01558 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NIFIFOHA_01559 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
NIFIFOHA_01560 4.8e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIFIFOHA_01561 1.4e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIFIFOHA_01562 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIFIFOHA_01563 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIFIFOHA_01564 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIFIFOHA_01565 2.4e-132 xerD D recombinase XerD
NIFIFOHA_01566 1.6e-168 cvfB S S1 domain
NIFIFOHA_01567 8.3e-268 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NIFIFOHA_01568 0.0 dnaE 2.7.7.7 L DNA polymerase
NIFIFOHA_01569 2.2e-265 XK27_08315 M Sulfatase
NIFIFOHA_01570 2.7e-139 yihY S Belongs to the UPF0761 family
NIFIFOHA_01571 3.8e-31 S Protein of unknown function (DUF2922)
NIFIFOHA_01572 1.3e-07
NIFIFOHA_01573 1.4e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
NIFIFOHA_01574 1.1e-118 rfbP M Bacterial sugar transferase
NIFIFOHA_01575 1.9e-146 cps1D M Domain of unknown function (DUF4422)
NIFIFOHA_01576 1.9e-95 cps3F
NIFIFOHA_01577 5.9e-45 M biosynthesis protein
NIFIFOHA_01578 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
NIFIFOHA_01579 1.2e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NIFIFOHA_01580 2.6e-72 S enterobacterial common antigen metabolic process
NIFIFOHA_01581 8.7e-62 acmD M repeat protein
NIFIFOHA_01584 2.4e-172 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NIFIFOHA_01585 1.6e-20 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NIFIFOHA_01586 1.7e-218 G Transporter, major facilitator family protein
NIFIFOHA_01587 4.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NIFIFOHA_01588 2.6e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NIFIFOHA_01589 4.6e-56 ydiI Q Thioesterase superfamily
NIFIFOHA_01590 6.2e-37 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NIFIFOHA_01591 5.5e-61 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIFIFOHA_01592 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NIFIFOHA_01593 8.2e-163 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIFIFOHA_01594 6.1e-13 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NIFIFOHA_01595 9.4e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NIFIFOHA_01596 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIFIFOHA_01597 6.2e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIFIFOHA_01598 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIFIFOHA_01599 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIFIFOHA_01600 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NIFIFOHA_01601 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIFIFOHA_01602 7.8e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NIFIFOHA_01603 9e-242 purD 6.3.4.13 F Belongs to the GARS family
NIFIFOHA_01604 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIFIFOHA_01605 2.6e-23 S Enoyl-(Acyl carrier protein) reductase
NIFIFOHA_01606 1.9e-172 K Bacterial regulatory helix-turn-helix protein, lysR family
NIFIFOHA_01607 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
NIFIFOHA_01608 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIFIFOHA_01609 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
NIFIFOHA_01610 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIFIFOHA_01611 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIFIFOHA_01612 8.3e-70 esbA S Family of unknown function (DUF5322)
NIFIFOHA_01613 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
NIFIFOHA_01614 2.8e-108 XK27_02070 S Nitroreductase family
NIFIFOHA_01615 2.3e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
NIFIFOHA_01616 2.9e-117 yecS E ABC transporter permease
NIFIFOHA_01617 8.4e-22 M Glycosyltransferase like family 2
NIFIFOHA_01618 1.5e-69 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
NIFIFOHA_01619 4.7e-41 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIFIFOHA_01620 5.4e-50 ybjQ S Belongs to the UPF0145 family
NIFIFOHA_01621 1.2e-76 rocF 3.5.3.1, 3.5.3.11 E Arginase family
NIFIFOHA_01623 7.9e-174 1.3.1.9 S Nitronate monooxygenase
NIFIFOHA_01624 4.7e-54 K Helix-turn-helix domain
NIFIFOHA_01625 6.2e-105 S Domain of unknown function (DUF4767)
NIFIFOHA_01626 1.4e-77
NIFIFOHA_01627 9.3e-09 S Domain of unknown function (DUF4767)
NIFIFOHA_01628 2e-127 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NIFIFOHA_01629 1.1e-192 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NIFIFOHA_01630 2.5e-161 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NIFIFOHA_01631 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
NIFIFOHA_01632 1.8e-38 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIFIFOHA_01633 3e-102 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NIFIFOHA_01634 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
NIFIFOHA_01635 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIFIFOHA_01636 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
NIFIFOHA_01637 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NIFIFOHA_01638 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIFIFOHA_01639 4.7e-39 ptsH G phosphocarrier protein HPR
NIFIFOHA_01641 0.0 clpE O Belongs to the ClpA ClpB family
NIFIFOHA_01642 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
NIFIFOHA_01643 1.1e-109 pncA Q Isochorismatase family
NIFIFOHA_01644 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
NIFIFOHA_01645 0.0 yhcA V ABC transporter, ATP-binding protein
NIFIFOHA_01646 6.7e-49 S FMN_bind
NIFIFOHA_01647 2e-66 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIFIFOHA_01648 2.8e-134 P nitric oxide dioxygenase activity
NIFIFOHA_01649 6.8e-49 XK27_08850 S Aminoacyl-tRNA editing domain
NIFIFOHA_01650 5.9e-165 M Membrane
NIFIFOHA_01651 3.4e-23 XK27_06785 V ABC transporter
NIFIFOHA_01652 2.2e-102 K Transcriptional regulator
NIFIFOHA_01653 2.6e-129 K Transcriptional regulatory protein, C-terminal domain protein
NIFIFOHA_01654 5.1e-159 pstS P Phosphate
NIFIFOHA_01655 3.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
NIFIFOHA_01656 9.4e-153 pstA P Phosphate transport system permease protein PstA
NIFIFOHA_01657 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIFIFOHA_01658 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
NIFIFOHA_01659 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NIFIFOHA_01660 5.4e-40 ylqC S Belongs to the UPF0109 family
NIFIFOHA_01661 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIFIFOHA_01662 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NIFIFOHA_01663 2.2e-260 yfnA E Amino Acid
NIFIFOHA_01664 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIFIFOHA_01666 1.2e-141 ET Bacterial periplasmic substrate-binding proteins
NIFIFOHA_01667 2e-110 XK27_05795 P ABC transporter permease
NIFIFOHA_01668 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NIFIFOHA_01669 5.3e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIFIFOHA_01670 8.6e-159 sufD O Uncharacterized protein family (UPF0051)
NIFIFOHA_01671 5.1e-235 F Permease
NIFIFOHA_01672 3.9e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NIFIFOHA_01673 2.3e-62 lytE M LysM domain protein
NIFIFOHA_01674 2.7e-117 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NIFIFOHA_01675 1.8e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIFIFOHA_01676 5.9e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NIFIFOHA_01677 3.4e-135 ycsF S LamB/YcsF family
NIFIFOHA_01678 2.7e-211 ycsG P Natural resistance-associated macrophage protein
NIFIFOHA_01679 3.9e-207 EGP Major facilitator Superfamily
NIFIFOHA_01680 2.6e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NIFIFOHA_01681 1.1e-52 trxA O Belongs to the thioredoxin family
NIFIFOHA_01682 2.2e-152 mleP3 S Membrane transport protein
NIFIFOHA_01684 2.4e-76 cylA V abc transporter atp-binding protein
NIFIFOHA_01685 3.1e-60 cylB V ABC-2 type transporter
NIFIFOHA_01686 7e-27 K LytTr DNA-binding domain
NIFIFOHA_01687 4.8e-11 S Protein of unknown function (DUF3021)
NIFIFOHA_01689 5.1e-89
NIFIFOHA_01690 3.2e-77 F Nucleoside 2-deoxyribosyltransferase
NIFIFOHA_01691 1.8e-181 scrR3 K Transcriptional regulator, LacI family
NIFIFOHA_01692 3e-14
NIFIFOHA_01693 4.9e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NIFIFOHA_01694 0.0 asnB 6.3.5.4 E Aluminium induced protein
NIFIFOHA_01696 5.1e-146 L Transposase and inactivated derivatives
NIFIFOHA_01697 9.9e-08 S Bacterial transferase hexapeptide (six repeats)
NIFIFOHA_01698 3.9e-119 IQ Enoyl-(Acyl carrier protein) reductase
NIFIFOHA_01699 3.1e-198 gldA 1.1.1.6 C dehydrogenase
NIFIFOHA_01700 3.4e-17 xre K Helix-turn-helix domain
NIFIFOHA_01701 2.1e-51 S Sugar efflux transporter for intercellular exchange
NIFIFOHA_01702 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NIFIFOHA_01703 4.6e-45 S Protein conserved in bacteria
NIFIFOHA_01704 3.5e-97 ywrO S Flavodoxin-like fold
NIFIFOHA_01705 9.5e-152 tesE Q hydratase
NIFIFOHA_01706 1.5e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIFIFOHA_01707 2.5e-62 S Domain of unknown function (DUF4440)
NIFIFOHA_01708 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIFIFOHA_01709 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NIFIFOHA_01710 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIFIFOHA_01711 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIFIFOHA_01712 1.3e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIFIFOHA_01713 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIFIFOHA_01714 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIFIFOHA_01716 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NIFIFOHA_01717 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NIFIFOHA_01718 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIFIFOHA_01719 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIFIFOHA_01720 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIFIFOHA_01721 1.2e-163 S Tetratricopeptide repeat
NIFIFOHA_01722 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIFIFOHA_01723 2.9e-262 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIFIFOHA_01724 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIFIFOHA_01725 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
NIFIFOHA_01726 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NIFIFOHA_01727 0.0 comEC S Competence protein ComEC
NIFIFOHA_01728 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
NIFIFOHA_01729 3.8e-90 comEA L Competence protein ComEA
NIFIFOHA_01730 6.7e-198 ylbL T Belongs to the peptidase S16 family
NIFIFOHA_01731 2.8e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIFIFOHA_01732 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NIFIFOHA_01733 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NIFIFOHA_01734 2.8e-216 ftsW D Belongs to the SEDS family
NIFIFOHA_01735 0.0 typA T GTP-binding protein TypA
NIFIFOHA_01736 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NIFIFOHA_01737 2.4e-49 yktA S Belongs to the UPF0223 family
NIFIFOHA_01738 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIFIFOHA_01739 1.5e-74
NIFIFOHA_01740 2.2e-31 ykzG S Belongs to the UPF0356 family
NIFIFOHA_01741 2e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NIFIFOHA_01742 4.2e-74 spx4 1.20.4.1 P ArsC family
NIFIFOHA_01743 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIFIFOHA_01744 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIFIFOHA_01745 7.1e-124 S Repeat protein
NIFIFOHA_01746 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NIFIFOHA_01747 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIFIFOHA_01748 3e-306 S amidohydrolase
NIFIFOHA_01749 5.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIFIFOHA_01750 3.4e-58 XK27_04120 S Putative amino acid metabolism
NIFIFOHA_01751 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIFIFOHA_01753 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NIFIFOHA_01754 1.2e-32 cspB K Cold shock protein
NIFIFOHA_01755 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIFIFOHA_01757 4.8e-112 divIVA D DivIVA domain protein
NIFIFOHA_01758 1.3e-145 ylmH S S4 domain protein
NIFIFOHA_01759 6.8e-41 yggT S YGGT family
NIFIFOHA_01760 2.7e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIFIFOHA_01761 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIFIFOHA_01762 2.7e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIFIFOHA_01763 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIFIFOHA_01764 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIFIFOHA_01765 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIFIFOHA_01766 9.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIFIFOHA_01767 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NIFIFOHA_01768 7e-09 ftsL D Cell division protein FtsL
NIFIFOHA_01769 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIFIFOHA_01770 5.6e-79 mraZ K Belongs to the MraZ family
NIFIFOHA_01771 5.8e-58
NIFIFOHA_01772 1.2e-07 S Protein of unknown function (DUF4044)
NIFIFOHA_01773 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NIFIFOHA_01774 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIFIFOHA_01775 2.2e-162 rrmA 2.1.1.187 H Methyltransferase
NIFIFOHA_01776 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NIFIFOHA_01777 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NIFIFOHA_01778 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIFIFOHA_01779 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
NIFIFOHA_01780 1e-113 yjbH Q Thioredoxin
NIFIFOHA_01781 3.2e-205 coiA 3.6.4.12 S Competence protein
NIFIFOHA_01782 5.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIFIFOHA_01783 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIFIFOHA_01784 6e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NIFIFOHA_01789 6.1e-88 3.5.1.4, 6.3.5.6, 6.3.5.7 J Amidase
NIFIFOHA_01790 2.8e-151 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
NIFIFOHA_01791 1.1e-166 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIFIFOHA_01792 5.1e-133 pucR QT Purine catabolism regulatory protein-like family
NIFIFOHA_01793 4.2e-135 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
NIFIFOHA_01794 1.4e-178 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
NIFIFOHA_01795 4.8e-145 L 4.5 Transposon and IS
NIFIFOHA_01796 1.3e-28 L Transposase
NIFIFOHA_01797 3.1e-124 S Membrane
NIFIFOHA_01798 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIFIFOHA_01799 0.0 pepF E oligoendopeptidase F
NIFIFOHA_01800 1e-163 K helix_turn _helix lactose operon repressor
NIFIFOHA_01801 2.7e-140 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NIFIFOHA_01802 8.7e-78 K AsnC family
NIFIFOHA_01803 1e-81 uspA T universal stress protein
NIFIFOHA_01804 0.0 cas3 L CRISPR-associated helicase cas3
NIFIFOHA_01805 7.8e-297 casA L the current gene model (or a revised gene model) may contain a frame shift
NIFIFOHA_01806 3e-102 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
NIFIFOHA_01807 1.4e-195 casC L CT1975-like protein
NIFIFOHA_01808 1.1e-132 casD S CRISPR-associated protein (Cas_Cas5)
NIFIFOHA_01809 5.6e-110 casE S CRISPR_assoc
NIFIFOHA_01810 2e-135 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIFIFOHA_01811 2.1e-131 czcD P cation diffusion facilitator family transporter
NIFIFOHA_01812 4.5e-133 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 L Psort location Cytoplasmic, score
NIFIFOHA_01813 9.7e-13
NIFIFOHA_01814 1.2e-305 traI 5.99.1.2 L C-terminal repeat of topoisomerase
NIFIFOHA_01815 4e-23
NIFIFOHA_01816 3.4e-75
NIFIFOHA_01817 5.7e-07
NIFIFOHA_01818 1e-220 traK U TraM recognition site of TraD and TraG
NIFIFOHA_01819 1.7e-44
NIFIFOHA_01820 6.2e-57 S Single-strand binding protein family
NIFIFOHA_01821 9.9e-114 S PDDEXK-like domain of unknown function (DUF3799)
NIFIFOHA_01822 4.3e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIFIFOHA_01823 2.3e-241 yfnA E amino acid
NIFIFOHA_01824 3.2e-83 S NADPH-dependent FMN reductase
NIFIFOHA_01826 1.3e-156 L Thioesterase-like superfamily
NIFIFOHA_01827 3.1e-50 lacA S transferase hexapeptide repeat
NIFIFOHA_01828 6.2e-260 argH 4.3.2.1 E argininosuccinate lyase
NIFIFOHA_01829 4.7e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIFIFOHA_01830 2.4e-184 hoxN U High-affinity nickel-transport protein
NIFIFOHA_01831 5.9e-149 larE S NAD synthase
NIFIFOHA_01832 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIFIFOHA_01833 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NIFIFOHA_01834 1.7e-131 cpmA S AIR carboxylase
NIFIFOHA_01835 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
NIFIFOHA_01836 7e-124 K Crp-like helix-turn-helix domain
NIFIFOHA_01837 3.6e-143 L Transposase and inactivated derivatives, IS30 family
NIFIFOHA_01838 9.2e-253 G Major Facilitator
NIFIFOHA_01839 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NIFIFOHA_01840 9.4e-178 K Transcriptional regulator, LacI family
NIFIFOHA_01841 3.7e-158 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
NIFIFOHA_01842 4.6e-09
NIFIFOHA_01843 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NIFIFOHA_01845 6.9e-47
NIFIFOHA_01846 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NIFIFOHA_01847 6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NIFIFOHA_01848 1e-148 metQ1 P Belongs to the nlpA lipoprotein family
NIFIFOHA_01849 7.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIFIFOHA_01850 1.2e-97 metI P ABC transporter permease
NIFIFOHA_01851 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIFIFOHA_01852 7.4e-11 yicL EG EamA-like transporter family
NIFIFOHA_01853 2.6e-74 S Domain of unknown function (DUF4352)
NIFIFOHA_01854 0.0 1.3.5.4 C FAD binding domain
NIFIFOHA_01855 5.7e-169 K LysR substrate binding domain
NIFIFOHA_01856 4.1e-161 rssA S Phospholipase, patatin family
NIFIFOHA_01857 1.7e-213 phbA 2.3.1.9 I Belongs to the thiolase family
NIFIFOHA_01858 1.9e-179 S AI-2E family transporter
NIFIFOHA_01859 7.1e-20 S membrane transporter protein
NIFIFOHA_01860 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIFIFOHA_01861 1.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIFIFOHA_01862 1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIFIFOHA_01863 0.0 asnB 6.3.5.4 E Asparagine synthase
NIFIFOHA_01864 6.6e-220 lysP E amino acid
NIFIFOHA_01865 2.1e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIFIFOHA_01866 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
NIFIFOHA_01867 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
NIFIFOHA_01868 4.1e-111 K Transcriptional regulator, TetR family
NIFIFOHA_01870 4e-22
NIFIFOHA_01871 4.1e-248 cycA E Amino acid permease
NIFIFOHA_01872 7.4e-85 perR P Belongs to the Fur family
NIFIFOHA_01873 1.4e-254 EGP Major facilitator Superfamily
NIFIFOHA_01874 4.4e-97 tag 3.2.2.20 L glycosylase
NIFIFOHA_01875 5e-51
NIFIFOHA_01876 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIFIFOHA_01877 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIFIFOHA_01878 1.1e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIFIFOHA_01879 7.8e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
NIFIFOHA_01880 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIFIFOHA_01881 2.6e-42
NIFIFOHA_01882 4.7e-299 ytgP S Polysaccharide biosynthesis protein
NIFIFOHA_01883 1.6e-61 3.2.1.23 S Domain of unknown function DUF302
NIFIFOHA_01884 1.9e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIFIFOHA_01885 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
NIFIFOHA_01886 1.2e-85 uspA T Belongs to the universal stress protein A family
NIFIFOHA_01887 3.5e-255 S Putative peptidoglycan binding domain
NIFIFOHA_01888 9.7e-163 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIFIFOHA_01889 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
NIFIFOHA_01890 3.6e-111
NIFIFOHA_01891 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NIFIFOHA_01892 1.1e-119 S CAAX protease self-immunity
NIFIFOHA_01893 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIFIFOHA_01894 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NIFIFOHA_01895 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NIFIFOHA_01896 3.7e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIFIFOHA_01897 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NIFIFOHA_01898 2e-200 folP 2.5.1.15 H dihydropteroate synthase
NIFIFOHA_01900 1.7e-36
NIFIFOHA_01902 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NIFIFOHA_01903 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NIFIFOHA_01904 9.8e-56 yheA S Belongs to the UPF0342 family
NIFIFOHA_01905 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIFIFOHA_01906 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIFIFOHA_01908 1.4e-77 hit FG histidine triad
NIFIFOHA_01909 2.3e-133 ecsA V ABC transporter, ATP-binding protein
NIFIFOHA_01910 2.9e-210 ecsB U ABC transporter
NIFIFOHA_01911 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIFIFOHA_01912 3.3e-58 ytzB S Small secreted protein
NIFIFOHA_01913 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIFIFOHA_01914 7.8e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIFIFOHA_01915 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NIFIFOHA_01916 4e-114 ybhL S Belongs to the BI1 family
NIFIFOHA_01917 5e-139 aroD S Serine hydrolase (FSH1)
NIFIFOHA_01918 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIFIFOHA_01919 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIFIFOHA_01920 3.9e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIFIFOHA_01921 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIFIFOHA_01922 3.6e-252 dnaB L replication initiation and membrane attachment
NIFIFOHA_01923 2.1e-171 dnaI L Primosomal protein DnaI
NIFIFOHA_01924 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIFIFOHA_01925 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NIFIFOHA_01926 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIFIFOHA_01927 1.9e-19 yoaK S Protein of unknown function (DUF1275)
NIFIFOHA_01928 1.6e-25 yoaK S Protein of unknown function (DUF1275)
NIFIFOHA_01929 2.2e-96 yqeG S HAD phosphatase, family IIIA
NIFIFOHA_01930 7.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
NIFIFOHA_01931 2.6e-49 yhbY J RNA-binding protein
NIFIFOHA_01932 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIFIFOHA_01933 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NIFIFOHA_01934 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIFIFOHA_01935 4.5e-140 yqeM Q Methyltransferase
NIFIFOHA_01936 1.7e-215 ylbM S Belongs to the UPF0348 family
NIFIFOHA_01937 1.2e-97 yceD S Uncharacterized ACR, COG1399
NIFIFOHA_01938 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NIFIFOHA_01939 5.6e-121 K response regulator
NIFIFOHA_01940 7.6e-280 arlS 2.7.13.3 T Histidine kinase
NIFIFOHA_01941 1.6e-233 V MatE
NIFIFOHA_01942 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIFIFOHA_01943 7.2e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIFIFOHA_01944 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NIFIFOHA_01945 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIFIFOHA_01946 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIFIFOHA_01947 7.8e-60 yodB K Transcriptional regulator, HxlR family
NIFIFOHA_01948 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIFIFOHA_01949 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIFIFOHA_01950 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NIFIFOHA_01951 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIFIFOHA_01952 0.0 S membrane
NIFIFOHA_01953 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NIFIFOHA_01954 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIFIFOHA_01955 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIFIFOHA_01956 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
NIFIFOHA_01957 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NIFIFOHA_01958 1.2e-180 glk 2.7.1.2 G Glucokinase
NIFIFOHA_01959 1.5e-71 yqhL P Rhodanese-like protein
NIFIFOHA_01960 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
NIFIFOHA_01961 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIFIFOHA_01962 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
NIFIFOHA_01963 4.7e-13
NIFIFOHA_01964 2.4e-148
NIFIFOHA_01965 1.1e-175
NIFIFOHA_01966 1.5e-92 dut S Protein conserved in bacteria
NIFIFOHA_01967 1.5e-200 S Phage integrase family
NIFIFOHA_01970 7.8e-54
NIFIFOHA_01971 1.6e-17 L nuclease
NIFIFOHA_01972 2.7e-43 kcsA P Ion transport protein
NIFIFOHA_01974 9.5e-217 M Glycosyl transferase family group 2
NIFIFOHA_01976 1.3e-172 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIFIFOHA_01977 1.1e-64 S Initiator Replication protein
NIFIFOHA_01979 2.4e-51 L Resolvase, N terminal domain
NIFIFOHA_01980 1e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NIFIFOHA_01981 4.8e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NIFIFOHA_01982 2.5e-40 gcvR T Belongs to the UPF0237 family
NIFIFOHA_01983 2.1e-244 XK27_08635 S UPF0210 protein
NIFIFOHA_01984 4e-178 yobV1 K WYL domain
NIFIFOHA_01985 2.1e-67 S pyridoxamine 5-phosphate
NIFIFOHA_01986 5.7e-35
NIFIFOHA_01989 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
NIFIFOHA_01990 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
NIFIFOHA_01991 8.8e-124 C nitroreductase
NIFIFOHA_01992 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NIFIFOHA_01993 1.3e-120 arcC 2.7.2.2 E Amino acid kinase family
NIFIFOHA_01996 7.3e-41 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
NIFIFOHA_01997 2.1e-65 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
NIFIFOHA_01998 3.9e-25 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
NIFIFOHA_01999 5e-38 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
NIFIFOHA_02000 2.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)