ORF_ID e_value Gene_name EC_number CAZy COGs Description
IAEFAFEP_00001 6.1e-183 fecB P Periplasmic binding protein
IAEFAFEP_00002 4.2e-272 sufB O assembly protein SufB
IAEFAFEP_00003 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
IAEFAFEP_00004 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAEFAFEP_00005 1.3e-243 sufD O FeS assembly protein SufD
IAEFAFEP_00006 8.5e-145 sufC O FeS assembly ATPase SufC
IAEFAFEP_00007 1.4e-33 feoA P FeoA domain
IAEFAFEP_00008 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IAEFAFEP_00009 6.7e-23 S Virus attachment protein p12 family
IAEFAFEP_00010 6.4e-157 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IAEFAFEP_00011 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAEFAFEP_00012 5.7e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_00013 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
IAEFAFEP_00014 7.4e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAEFAFEP_00015 1.5e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IAEFAFEP_00016 1.5e-161 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAEFAFEP_00017 2.6e-21 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAEFAFEP_00018 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
IAEFAFEP_00019 6.4e-213 ydiN G Major Facilitator Superfamily
IAEFAFEP_00021 4.8e-242 dtpT U amino acid peptide transporter
IAEFAFEP_00024 5.1e-153 S Sucrose-6F-phosphate phosphohydrolase
IAEFAFEP_00025 7.2e-158 1.6.5.2 GM NAD(P)H-binding
IAEFAFEP_00026 5.5e-158 S Alpha beta hydrolase
IAEFAFEP_00027 2.7e-237 lmrB EGP Major facilitator Superfamily
IAEFAFEP_00029 0.0 S Bacterial membrane protein YfhO
IAEFAFEP_00030 6.6e-12
IAEFAFEP_00031 1.6e-49
IAEFAFEP_00032 0.0 kup P Transport of potassium into the cell
IAEFAFEP_00034 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAEFAFEP_00035 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IAEFAFEP_00036 0.0 yjbQ P TrkA C-terminal domain protein
IAEFAFEP_00037 1.1e-275 pipD E Dipeptidase
IAEFAFEP_00038 3.4e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IAEFAFEP_00039 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IAEFAFEP_00040 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAEFAFEP_00041 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
IAEFAFEP_00042 2.1e-159 EGP Major facilitator Superfamily
IAEFAFEP_00043 3.4e-201 mdtG EGP Major facilitator Superfamily
IAEFAFEP_00044 1.3e-249 yhdP S Transporter associated domain
IAEFAFEP_00045 2.7e-11 naiP EGP Major facilitator Superfamily
IAEFAFEP_00046 5.1e-95 ps461 3.5.1.104 M hydrolase, family 25
IAEFAFEP_00047 8.8e-23 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IAEFAFEP_00051 1.6e-13
IAEFAFEP_00052 1.2e-30 S GDSL-like Lipase/Acylhydrolase
IAEFAFEP_00055 3.1e-58 spoIVFA GT2,GT4 D peptidase
IAEFAFEP_00056 1.6e-141 rny D peptidase
IAEFAFEP_00057 5.9e-80 S Phage tail protein
IAEFAFEP_00058 1.8e-201 M Phage tail tape measure protein TP901
IAEFAFEP_00059 1.4e-26
IAEFAFEP_00060 9.3e-49 S Phage tail tube protein
IAEFAFEP_00061 1.8e-26
IAEFAFEP_00062 1.2e-18
IAEFAFEP_00063 1.9e-32 S Phage head-tail joining protein
IAEFAFEP_00064 1.3e-29 S Phage gp6-like head-tail connector protein
IAEFAFEP_00065 5e-122 S Phage capsid family
IAEFAFEP_00066 4.9e-78 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IAEFAFEP_00067 4.4e-143 S portal protein
IAEFAFEP_00069 1e-267 S Phage Terminase
IAEFAFEP_00070 7.4e-40 L Phage terminase, small subunit
IAEFAFEP_00071 1.3e-33 L HNH nucleases
IAEFAFEP_00072 4.2e-29
IAEFAFEP_00080 3.2e-14
IAEFAFEP_00081 1.6e-20
IAEFAFEP_00082 1.5e-17 mazG S MazG nucleotide pyrophosphohydrolase domain
IAEFAFEP_00091 1.4e-83 Q DNA (cytosine-5-)-methyltransferase activity
IAEFAFEP_00095 6.2e-20 S HNH nucleases
IAEFAFEP_00096 1.6e-41 rusA L Endodeoxyribonuclease RusA
IAEFAFEP_00100 4.4e-10 K Cro/C1-type HTH DNA-binding domain
IAEFAFEP_00102 2.5e-43 dnaC 3.4.21.53 L IstB-like ATP binding protein
IAEFAFEP_00103 5.8e-63 ybl78 L DnaD domain protein
IAEFAFEP_00104 1.8e-71 S Putative HNHc nuclease
IAEFAFEP_00105 5.8e-29 S Single-strand binding protein family
IAEFAFEP_00106 1.4e-161 S PDDEXK-like domain of unknown function (DUF3799)
IAEFAFEP_00107 7.7e-140 S DNA metabolic process
IAEFAFEP_00111 8.9e-13 S Domain of unknown function (DUF771)
IAEFAFEP_00115 2.2e-121 S DNA binding
IAEFAFEP_00116 1.9e-17 cro K Helix-turn-helix XRE-family like proteins
IAEFAFEP_00117 2.1e-64 3.4.21.88 KT Peptidase S24-like
IAEFAFEP_00119 2.1e-101 L Belongs to the 'phage' integrase family
IAEFAFEP_00120 4.3e-195 naiP EGP Major facilitator Superfamily
IAEFAFEP_00121 1.7e-15 K LysR substrate binding domain protein
IAEFAFEP_00122 7.2e-52 K Transcriptional regulator
IAEFAFEP_00123 2.2e-215 E GDSL-like Lipase/Acylhydrolase family
IAEFAFEP_00124 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IAEFAFEP_00125 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
IAEFAFEP_00126 1.4e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IAEFAFEP_00127 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IAEFAFEP_00128 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IAEFAFEP_00129 1.1e-09 yphJ 4.1.1.44 S decarboxylase
IAEFAFEP_00130 1e-30 yphJ 4.1.1.44 S decarboxylase
IAEFAFEP_00131 2.8e-54 azlD E Branched-chain amino acid transport
IAEFAFEP_00132 2.3e-122 azlC E azaleucine resistance protein AzlC
IAEFAFEP_00133 1.9e-286 thrC 4.2.3.1 E Threonine synthase
IAEFAFEP_00134 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IAEFAFEP_00135 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IAEFAFEP_00136 3.5e-99 K Acetyltransferase (GNAT) domain
IAEFAFEP_00137 5.3e-113 ylbE GM NAD(P)H-binding
IAEFAFEP_00138 1.8e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAEFAFEP_00139 4.5e-132 S Belongs to the UPF0246 family
IAEFAFEP_00140 1.3e-97
IAEFAFEP_00141 3e-159 degV S EDD domain protein, DegV family
IAEFAFEP_00142 0.0 FbpA K Fibronectin-binding protein
IAEFAFEP_00143 1.3e-102 P nitric oxide dioxygenase activity
IAEFAFEP_00144 2.1e-48 C Flavodoxin
IAEFAFEP_00145 1.2e-35 S Bacterial transferase hexapeptide (six repeats)
IAEFAFEP_00146 5.1e-29 akr5f 1.1.1.346 S reductase
IAEFAFEP_00147 4e-24 akr5f 1.1.1.346 S reductase
IAEFAFEP_00148 6.1e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IAEFAFEP_00149 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IAEFAFEP_00150 6.2e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAEFAFEP_00151 1.4e-136 cof S haloacid dehalogenase-like hydrolase
IAEFAFEP_00152 1.1e-19 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IAEFAFEP_00153 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IAEFAFEP_00154 6.8e-113 yfbR S HD containing hydrolase-like enzyme
IAEFAFEP_00156 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IAEFAFEP_00157 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IAEFAFEP_00158 6.9e-206
IAEFAFEP_00159 3.2e-161 rapZ S Displays ATPase and GTPase activities
IAEFAFEP_00160 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IAEFAFEP_00161 6e-166 whiA K May be required for sporulation
IAEFAFEP_00162 5e-119 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAEFAFEP_00163 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IAEFAFEP_00167 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
IAEFAFEP_00168 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAEFAFEP_00169 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
IAEFAFEP_00170 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IAEFAFEP_00171 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAEFAFEP_00172 4.7e-39 ptsH G phosphocarrier protein HPR
IAEFAFEP_00174 0.0 clpE O Belongs to the ClpA ClpB family
IAEFAFEP_00175 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
IAEFAFEP_00176 6.4e-110 pncA Q Isochorismatase family
IAEFAFEP_00177 1.3e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAEFAFEP_00178 1.7e-97 S Pfam:DUF3816
IAEFAFEP_00179 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IAEFAFEP_00180 8.4e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAEFAFEP_00181 6.5e-162 EG EamA-like transporter family
IAEFAFEP_00182 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
IAEFAFEP_00184 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00187 4e-22
IAEFAFEP_00188 4.5e-247 cycA E Amino acid permease
IAEFAFEP_00189 4.8e-84 perR P Belongs to the Fur family
IAEFAFEP_00190 5.2e-254 EGP Major facilitator Superfamily
IAEFAFEP_00191 4.4e-97 tag 3.2.2.20 L glycosylase
IAEFAFEP_00192 8.5e-51
IAEFAFEP_00193 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAEFAFEP_00194 4.8e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAEFAFEP_00195 9.9e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAEFAFEP_00196 4.1e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
IAEFAFEP_00197 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAEFAFEP_00198 2.6e-42
IAEFAFEP_00199 8e-299 ytgP S Polysaccharide biosynthesis protein
IAEFAFEP_00200 3.5e-97 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00201 6.1e-10 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAEFAFEP_00202 1.2e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAEFAFEP_00203 1.9e-186 yegS 2.7.1.107 G Lipid kinase
IAEFAFEP_00204 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAEFAFEP_00205 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IAEFAFEP_00206 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAEFAFEP_00207 4.6e-165 camS S sex pheromone
IAEFAFEP_00208 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAEFAFEP_00209 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IAEFAFEP_00210 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAEFAFEP_00211 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IAEFAFEP_00212 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IAEFAFEP_00213 1.2e-138 IQ reductase
IAEFAFEP_00214 2.9e-125 tnp L DDE domain
IAEFAFEP_00215 4.9e-103
IAEFAFEP_00217 8.8e-30 S Protein of unknown function (DUF3021)
IAEFAFEP_00218 3.1e-27 K LytTr DNA-binding domain
IAEFAFEP_00219 6.6e-32 K Transcriptional regulator, ArsR family
IAEFAFEP_00220 6.2e-57 P Cadmium resistance transporter
IAEFAFEP_00221 8e-42 S RelB antitoxin
IAEFAFEP_00222 2.7e-13
IAEFAFEP_00223 6.7e-156 repA S Replication initiator protein A
IAEFAFEP_00225 1.1e-141 D CobQ CobB MinD ParA nucleotide binding domain protein
IAEFAFEP_00226 1.4e-93 L Resolvase, N terminal domain
IAEFAFEP_00227 8.1e-236 EGP Major Facilitator Superfamily
IAEFAFEP_00228 2.1e-311 mco Q Multicopper oxidase
IAEFAFEP_00229 6.8e-24
IAEFAFEP_00230 6.1e-18 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IAEFAFEP_00231 0.0 asnB 6.3.5.4 E Aluminium induced protein
IAEFAFEP_00233 3.8e-103 L Transposase and inactivated derivatives
IAEFAFEP_00234 1e-188 EGP Major facilitator Superfamily
IAEFAFEP_00237 5.1e-104 S Bacterial transferase hexapeptide (six repeats)
IAEFAFEP_00238 7.8e-120 IQ Enoyl-(Acyl carrier protein) reductase
IAEFAFEP_00239 2.8e-199 gldA 1.1.1.6 C dehydrogenase
IAEFAFEP_00240 4.5e-17 xre K Helix-turn-helix domain
IAEFAFEP_00241 2.1e-51 S Sugar efflux transporter for intercellular exchange
IAEFAFEP_00242 2e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IAEFAFEP_00243 9e-22 S Protein conserved in bacteria
IAEFAFEP_00244 1.8e-98 ywrO S Flavodoxin-like fold
IAEFAFEP_00245 1.7e-41 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IAEFAFEP_00246 2.5e-152 tesE Q hydratase
IAEFAFEP_00247 1.9e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_00248 3.6e-61 S Domain of unknown function (DUF4440)
IAEFAFEP_00249 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAEFAFEP_00250 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IAEFAFEP_00251 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IAEFAFEP_00252 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IAEFAFEP_00253 1.9e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAEFAFEP_00254 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IAEFAFEP_00255 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAEFAFEP_00257 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IAEFAFEP_00258 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IAEFAFEP_00259 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAEFAFEP_00260 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IAEFAFEP_00261 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAEFAFEP_00262 1.2e-163 S Tetratricopeptide repeat
IAEFAFEP_00263 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAEFAFEP_00264 1.9e-261 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAEFAFEP_00265 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAEFAFEP_00266 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
IAEFAFEP_00267 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
IAEFAFEP_00268 0.0 comEC S Competence protein ComEC
IAEFAFEP_00269 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
IAEFAFEP_00270 3.8e-90 comEA L Competence protein ComEA
IAEFAFEP_00271 6.7e-198 ylbL T Belongs to the peptidase S16 family
IAEFAFEP_00272 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAEFAFEP_00273 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IAEFAFEP_00274 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IAEFAFEP_00275 2e-214 ftsW D Belongs to the SEDS family
IAEFAFEP_00276 0.0 typA T GTP-binding protein TypA
IAEFAFEP_00277 1.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IAEFAFEP_00278 2.4e-49 yktA S Belongs to the UPF0223 family
IAEFAFEP_00279 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IAEFAFEP_00280 9.8e-74
IAEFAFEP_00281 6.5e-31 ykzG S Belongs to the UPF0356 family
IAEFAFEP_00282 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IAEFAFEP_00283 4.2e-74 spx4 1.20.4.1 P ArsC family
IAEFAFEP_00284 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAEFAFEP_00285 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IAEFAFEP_00286 7.1e-124 S Repeat protein
IAEFAFEP_00287 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IAEFAFEP_00288 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAEFAFEP_00289 1.3e-306 S amidohydrolase
IAEFAFEP_00290 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IAEFAFEP_00291 3.4e-58 XK27_04120 S Putative amino acid metabolism
IAEFAFEP_00292 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAEFAFEP_00294 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IAEFAFEP_00295 1.2e-32 cspB K Cold shock protein
IAEFAFEP_00296 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAEFAFEP_00298 4.8e-112 divIVA D DivIVA domain protein
IAEFAFEP_00299 2.9e-145 ylmH S S4 domain protein
IAEFAFEP_00300 6.8e-41 yggT S YGGT family
IAEFAFEP_00301 2.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IAEFAFEP_00302 4.5e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAEFAFEP_00303 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IAEFAFEP_00304 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IAEFAFEP_00305 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAEFAFEP_00306 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAEFAFEP_00307 3.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAEFAFEP_00308 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IAEFAFEP_00309 7e-09 ftsL D Cell division protein FtsL
IAEFAFEP_00310 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IAEFAFEP_00311 1.2e-79 mraZ K Belongs to the MraZ family
IAEFAFEP_00312 9.8e-58
IAEFAFEP_00313 1.2e-07 S Protein of unknown function (DUF4044)
IAEFAFEP_00314 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IAEFAFEP_00315 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IAEFAFEP_00316 2.5e-163 rrmA 2.1.1.187 H Methyltransferase
IAEFAFEP_00317 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IAEFAFEP_00318 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IAEFAFEP_00319 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAEFAFEP_00320 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
IAEFAFEP_00321 8.1e-108 yjbH Q Thioredoxin
IAEFAFEP_00322 9.4e-205 coiA 3.6.4.12 S Competence protein
IAEFAFEP_00323 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IAEFAFEP_00324 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IAEFAFEP_00325 4.6e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IAEFAFEP_00326 3.1e-13 lacA 3.2.1.23 G -beta-galactosidase
IAEFAFEP_00327 3.8e-213 nupG F Nucleoside transporter
IAEFAFEP_00328 2.2e-144 rihC 3.2.2.1 F Nucleoside
IAEFAFEP_00329 1.3e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IAEFAFEP_00330 4.6e-158 noc K Belongs to the ParB family
IAEFAFEP_00331 1e-145 spo0J K Belongs to the ParB family
IAEFAFEP_00332 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
IAEFAFEP_00333 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IAEFAFEP_00334 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
IAEFAFEP_00335 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAEFAFEP_00336 3.1e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAEFAFEP_00337 8.2e-129 epsB M biosynthesis protein
IAEFAFEP_00338 6.1e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IAEFAFEP_00339 1.1e-138 ywqE 3.1.3.48 GM PHP domain protein
IAEFAFEP_00340 5.2e-89 capM M Bacterial sugar transferase
IAEFAFEP_00341 5e-85 GT4 G Glycosyl transferase 4-like
IAEFAFEP_00342 1.9e-145 3.5.1.47 E Peptidase dimerisation domain
IAEFAFEP_00343 1.2e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
IAEFAFEP_00344 2.2e-70 yxeN U ABC transporter, permease protein
IAEFAFEP_00345 5.4e-47 yxeL K acetyltransferase
IAEFAFEP_00346 1.8e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
IAEFAFEP_00348 4.8e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IAEFAFEP_00349 1.9e-44 metC1 2.5.1.48, 4.4.1.8 E cystathionine
IAEFAFEP_00350 6e-163 metC1 2.5.1.48, 4.4.1.8 E cystathionine
IAEFAFEP_00351 3.5e-85 slyA K Transcriptional regulator
IAEFAFEP_00352 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IAEFAFEP_00353 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAEFAFEP_00354 4.4e-58
IAEFAFEP_00355 6.8e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IAEFAFEP_00356 2e-177 prmA J Ribosomal protein L11 methyltransferase
IAEFAFEP_00357 1.2e-54
IAEFAFEP_00359 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAEFAFEP_00370 1.3e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
IAEFAFEP_00371 9e-142 ET Bacterial periplasmic substrate-binding proteins
IAEFAFEP_00372 2e-110 XK27_05795 P ABC transporter permease
IAEFAFEP_00373 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IAEFAFEP_00374 5.3e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAEFAFEP_00375 5.4e-161 sufD O Uncharacterized protein family (UPF0051)
IAEFAFEP_00376 4.6e-236 F Permease
IAEFAFEP_00377 1e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IAEFAFEP_00378 4.7e-66 lytE M LysM domain protein
IAEFAFEP_00379 6.2e-85 ykhA 3.1.2.20 I Thioesterase superfamily
IAEFAFEP_00380 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IAEFAFEP_00381 1.2e-115 K Transcriptional regulator, TetR family
IAEFAFEP_00382 4.3e-183
IAEFAFEP_00383 5.9e-76
IAEFAFEP_00384 2.1e-65 yjcE P Sodium proton antiporter
IAEFAFEP_00385 2.4e-49 ywnB S NAD(P)H-binding
IAEFAFEP_00386 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAEFAFEP_00387 2.2e-96 V VanZ like family
IAEFAFEP_00388 2.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IAEFAFEP_00389 6.1e-60 yneR
IAEFAFEP_00390 1.9e-181 K Transcriptional regulator, LacI family
IAEFAFEP_00391 1.6e-228 gntT EG Gluconate
IAEFAFEP_00392 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IAEFAFEP_00393 1.6e-171 mutR K Transcriptional activator, Rgg GadR MutR family
IAEFAFEP_00394 9e-12 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IAEFAFEP_00395 9.7e-74 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IAEFAFEP_00396 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00397 3.8e-85 macB_3 V FtsX-like permease family
IAEFAFEP_00398 2.9e-85 macB_3 V FtsX-like permease family
IAEFAFEP_00399 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IAEFAFEP_00400 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IAEFAFEP_00401 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAEFAFEP_00403 3.5e-188 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAEFAFEP_00405 1.2e-226 glnP P ABC transporter
IAEFAFEP_00406 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAEFAFEP_00407 1e-251 cycA E Amino acid permease
IAEFAFEP_00408 1.6e-208 EGP Major facilitator Superfamily
IAEFAFEP_00409 2.7e-211 ycsG P Natural resistance-associated macrophage protein
IAEFAFEP_00410 2e-124 ycsF S LamB/YcsF family
IAEFAFEP_00411 2.2e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IAEFAFEP_00412 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IAEFAFEP_00413 1.7e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IAEFAFEP_00414 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
IAEFAFEP_00415 2.3e-72 K helix_turn_helix, mercury resistance
IAEFAFEP_00416 5.9e-82 S Psort location Cytoplasmic, score
IAEFAFEP_00417 4.2e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IAEFAFEP_00418 9.9e-94 wecD K Acetyltransferase (GNAT) family
IAEFAFEP_00419 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
IAEFAFEP_00420 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
IAEFAFEP_00421 1.1e-23 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
IAEFAFEP_00422 1.1e-26 L Transposase and inactivated derivatives IS30 family
IAEFAFEP_00423 0.0 mco Q Multicopper oxidase
IAEFAFEP_00424 2.8e-51 K 2 iron, 2 sulfur cluster binding
IAEFAFEP_00425 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IAEFAFEP_00426 6.3e-120 Q Methyltransferase domain
IAEFAFEP_00428 2.3e-102 S CAAX protease self-immunity
IAEFAFEP_00429 5.4e-100 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAEFAFEP_00430 1.7e-39 fsr EGP Major Facilitator Superfamily
IAEFAFEP_00431 8.5e-74 fsr EGP Major Facilitator Superfamily
IAEFAFEP_00432 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
IAEFAFEP_00433 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IAEFAFEP_00434 1.6e-105
IAEFAFEP_00435 2e-85 dps P Belongs to the Dps family
IAEFAFEP_00436 8.2e-304 ybiT S ABC transporter, ATP-binding protein
IAEFAFEP_00437 7.5e-20 L Transposase and inactivated derivatives IS30 family
IAEFAFEP_00438 2.9e-235 kgtP EGP Sugar (and other) transporter
IAEFAFEP_00439 5.4e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
IAEFAFEP_00440 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAEFAFEP_00441 6.3e-149 isdE P Periplasmic binding protein
IAEFAFEP_00442 1e-94 M Iron Transport-associated domain
IAEFAFEP_00443 3.4e-269 isdH M Iron Transport-associated domain
IAEFAFEP_00444 1.3e-45
IAEFAFEP_00445 1.5e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAEFAFEP_00446 3.9e-31 ydzE EG spore germination
IAEFAFEP_00447 3.1e-93 P Cadmium resistance transporter
IAEFAFEP_00448 1.7e-134 IQ Dehydrogenase reductase
IAEFAFEP_00449 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAEFAFEP_00450 2.5e-161 EG EamA-like transporter family
IAEFAFEP_00451 0.0 helD 3.6.4.12 L DNA helicase
IAEFAFEP_00452 1.6e-117 dedA S SNARE associated Golgi protein
IAEFAFEP_00453 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IAEFAFEP_00454 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAEFAFEP_00455 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00456 1.1e-178 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_00457 7e-36 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
IAEFAFEP_00458 3e-85 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
IAEFAFEP_00459 2.8e-63 pucR QT Purine catabolism regulatory protein-like family
IAEFAFEP_00460 3.9e-129 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IAEFAFEP_00461 1.7e-98 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
IAEFAFEP_00462 7.7e-202 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IAEFAFEP_00463 1.2e-11 sucD 6.2.1.5 C CoA-ligase
IAEFAFEP_00464 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IAEFAFEP_00465 3e-124 C nitroreductase
IAEFAFEP_00466 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
IAEFAFEP_00467 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
IAEFAFEP_00468 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
IAEFAFEP_00469 6.2e-76 argR K Regulates arginine biosynthesis genes
IAEFAFEP_00470 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IAEFAFEP_00471 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IAEFAFEP_00472 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAEFAFEP_00473 6.1e-258 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IAEFAFEP_00474 1e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAEFAFEP_00475 8.9e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAEFAFEP_00476 9e-72 yqhY S Asp23 family, cell envelope-related function
IAEFAFEP_00477 4e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAEFAFEP_00478 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IAEFAFEP_00479 9e-53 ysxB J Cysteine protease Prp
IAEFAFEP_00480 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IAEFAFEP_00481 9.6e-115 K Transcriptional regulator
IAEFAFEP_00483 6.6e-93 dut S Protein conserved in bacteria
IAEFAFEP_00484 2.3e-176
IAEFAFEP_00485 7e-148
IAEFAFEP_00486 4.7e-13
IAEFAFEP_00487 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
IAEFAFEP_00488 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAEFAFEP_00489 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
IAEFAFEP_00490 1.5e-71 yqhL P Rhodanese-like protein
IAEFAFEP_00491 1.2e-180 glk 2.7.1.2 G Glucokinase
IAEFAFEP_00492 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IAEFAFEP_00493 6.9e-116 gluP 3.4.21.105 S Peptidase, S54 family
IAEFAFEP_00494 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAEFAFEP_00495 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAEFAFEP_00496 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IAEFAFEP_00497 0.0 S membrane
IAEFAFEP_00498 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAEFAFEP_00499 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
IAEFAFEP_00500 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAEFAFEP_00501 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAEFAFEP_00502 8.6e-59 yodB K Transcriptional regulator, HxlR family
IAEFAFEP_00503 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAEFAFEP_00504 3.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAEFAFEP_00505 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IAEFAFEP_00506 7.2e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAEFAFEP_00507 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IAEFAFEP_00508 1.6e-233 V MatE
IAEFAFEP_00509 2e-280 arlS 2.7.13.3 T Histidine kinase
IAEFAFEP_00510 5.6e-121 K response regulator
IAEFAFEP_00511 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IAEFAFEP_00512 4.6e-97 yceD S Uncharacterized ACR, COG1399
IAEFAFEP_00513 9.3e-214 ylbM S Belongs to the UPF0348 family
IAEFAFEP_00514 8.3e-142 yqeM Q Methyltransferase
IAEFAFEP_00515 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IAEFAFEP_00516 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IAEFAFEP_00517 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAEFAFEP_00518 2.6e-49 yhbY J RNA-binding protein
IAEFAFEP_00519 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
IAEFAFEP_00520 2.2e-96 yqeG S HAD phosphatase, family IIIA
IAEFAFEP_00521 9.7e-24 yoaK S Protein of unknown function (DUF1275)
IAEFAFEP_00522 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAEFAFEP_00523 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IAEFAFEP_00524 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAEFAFEP_00525 2.5e-172 dnaI L Primosomal protein DnaI
IAEFAFEP_00526 3e-251 dnaB L replication initiation and membrane attachment
IAEFAFEP_00527 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAEFAFEP_00528 1e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAEFAFEP_00529 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IAEFAFEP_00530 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAEFAFEP_00531 6.5e-139 aroD S Serine hydrolase (FSH1)
IAEFAFEP_00532 1.8e-114 ybhL S Belongs to the BI1 family
IAEFAFEP_00533 5.5e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IAEFAFEP_00534 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IAEFAFEP_00535 3.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IAEFAFEP_00536 5.1e-59 ytzB S Small secreted protein
IAEFAFEP_00537 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IAEFAFEP_00538 3.8e-210 ecsB U ABC transporter
IAEFAFEP_00539 2.3e-133 ecsA V ABC transporter, ATP-binding protein
IAEFAFEP_00540 1.4e-77 hit FG histidine triad
IAEFAFEP_00542 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IAEFAFEP_00543 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IAEFAFEP_00544 9.8e-56 yheA S Belongs to the UPF0342 family
IAEFAFEP_00545 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IAEFAFEP_00546 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IAEFAFEP_00548 1.7e-36
IAEFAFEP_00550 2.4e-201 folP 2.5.1.15 H dihydropteroate synthase
IAEFAFEP_00551 1.2e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IAEFAFEP_00552 1.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IAEFAFEP_00553 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IAEFAFEP_00554 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IAEFAFEP_00555 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAEFAFEP_00556 2e-118 S CAAX protease self-immunity
IAEFAFEP_00557 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IAEFAFEP_00558 3.6e-111
IAEFAFEP_00559 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
IAEFAFEP_00560 3.9e-164 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAEFAFEP_00561 3.2e-256 S Putative peptidoglycan binding domain
IAEFAFEP_00562 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00563 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAEFAFEP_00564 3.2e-102
IAEFAFEP_00565 9.5e-26
IAEFAFEP_00566 6.3e-171 scrR K Transcriptional regulator, LacI family
IAEFAFEP_00567 2.1e-171 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAEFAFEP_00568 1e-45 czrA K Transcriptional regulator, ArsR family
IAEFAFEP_00569 1.8e-75 argR K Regulates arginine biosynthesis genes
IAEFAFEP_00570 1.4e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IAEFAFEP_00571 5e-158 hrtB V ABC transporter permease
IAEFAFEP_00572 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
IAEFAFEP_00573 7.9e-70 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IAEFAFEP_00574 8.4e-22 M Glycosyltransferase like family 2
IAEFAFEP_00575 3.8e-117 yecS E ABC transporter permease
IAEFAFEP_00576 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
IAEFAFEP_00577 9.7e-109 XK27_02070 S Nitroreductase family
IAEFAFEP_00578 5.3e-71 rnhA 3.1.26.4 L Ribonuclease HI
IAEFAFEP_00579 1.7e-70 esbA S Family of unknown function (DUF5322)
IAEFAFEP_00580 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAEFAFEP_00581 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAEFAFEP_00582 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
IAEFAFEP_00583 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAEFAFEP_00584 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
IAEFAFEP_00585 4.2e-29 EGP Major facilitator Superfamily
IAEFAFEP_00586 0.0 copA 3.6.3.54 P P-type ATPase
IAEFAFEP_00587 2.3e-40 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IAEFAFEP_00588 1.1e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IAEFAFEP_00589 1.6e-177
IAEFAFEP_00590 1e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IAEFAFEP_00591 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAEFAFEP_00592 5.8e-241 purD 6.3.4.13 F Belongs to the GARS family
IAEFAFEP_00593 2.8e-86 S Protein of unknown function (DUF3644)
IAEFAFEP_00594 5.8e-44 3.4.21.88 K Helix-turn-helix domain
IAEFAFEP_00595 1.1e-15 K Helix-turn-helix XRE-family like proteins
IAEFAFEP_00596 8.9e-147 K Phage regulatory protein
IAEFAFEP_00600 7.2e-10 S Domain of unknown function (DUF771)
IAEFAFEP_00606 3.8e-93 recT L RecT family
IAEFAFEP_00607 1.5e-33 recT L RecT family
IAEFAFEP_00608 4.5e-152 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IAEFAFEP_00609 2e-94 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAEFAFEP_00610 1.4e-26 L Psort location Cytoplasmic, score
IAEFAFEP_00613 6.9e-200 S Domain of unknown function (DUF4432)
IAEFAFEP_00614 1.7e-114 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAEFAFEP_00615 3.7e-171 deoR K sugar-binding domain protein
IAEFAFEP_00616 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAEFAFEP_00617 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IAEFAFEP_00618 2.7e-244 fucP G Major Facilitator Superfamily
IAEFAFEP_00619 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAEFAFEP_00620 2.5e-75 S Core-2/I-Branching enzyme
IAEFAFEP_00621 4.7e-36 S Acyltransferase family
IAEFAFEP_00622 2.8e-93 S Cupin superfamily (DUF985)
IAEFAFEP_00623 1e-122 K response regulator
IAEFAFEP_00624 1e-207 hpk31 2.7.13.3 T Histidine kinase
IAEFAFEP_00625 2.6e-204 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IAEFAFEP_00626 7.6e-139 azlC E AzlC protein
IAEFAFEP_00627 1.2e-60 azlD S branched-chain amino acid
IAEFAFEP_00628 7e-124 K Crp-like helix-turn-helix domain
IAEFAFEP_00629 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
IAEFAFEP_00630 1.7e-131 cpmA S AIR carboxylase
IAEFAFEP_00631 9.2e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IAEFAFEP_00632 7.6e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IAEFAFEP_00633 6.5e-148 larE S NAD synthase
IAEFAFEP_00634 6.2e-185 hoxN U High-affinity nickel-transport protein
IAEFAFEP_00635 5.4e-253 G Major Facilitator
IAEFAFEP_00636 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IAEFAFEP_00637 1.6e-177 K Transcriptional regulator, LacI family
IAEFAFEP_00638 5.4e-157 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IAEFAFEP_00639 4.6e-09
IAEFAFEP_00640 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IAEFAFEP_00641 1.1e-21 E Zn peptidase
IAEFAFEP_00642 2e-23
IAEFAFEP_00643 3.7e-129 S Domain of unknown function (DUF4393)
IAEFAFEP_00645 8.9e-58
IAEFAFEP_00646 3.3e-200 L Belongs to the 'phage' integrase family
IAEFAFEP_00648 2.1e-90
IAEFAFEP_00649 3.8e-78 F Nucleoside 2-deoxyribosyltransferase
IAEFAFEP_00650 6.7e-184 scrR3 K Transcriptional regulator, LacI family
IAEFAFEP_00651 6.8e-13
IAEFAFEP_00652 1.7e-161 hrtB V ABC transporter permease
IAEFAFEP_00653 5.3e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IAEFAFEP_00654 4.5e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IAEFAFEP_00655 1.9e-74 K Copper transport repressor CopY TcrY
IAEFAFEP_00656 0.0 copB 3.6.3.4 P P-type ATPase
IAEFAFEP_00658 1.2e-251 mntH P H( )-stimulated, divalent metal cation uptake system
IAEFAFEP_00659 1.5e-21
IAEFAFEP_00660 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAEFAFEP_00661 4.1e-70 L nuclease
IAEFAFEP_00662 4.2e-161 F DNA/RNA non-specific endonuclease
IAEFAFEP_00663 1.6e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IAEFAFEP_00664 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAEFAFEP_00665 7.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAEFAFEP_00666 0.0 asnB 6.3.5.4 E Asparagine synthase
IAEFAFEP_00667 1.5e-219 lysP E amino acid
IAEFAFEP_00668 7.8e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IAEFAFEP_00669 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IAEFAFEP_00670 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAEFAFEP_00671 2.1e-146 jag S R3H domain protein
IAEFAFEP_00672 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IAEFAFEP_00673 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IAEFAFEP_00674 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IAEFAFEP_00676 1.4e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAEFAFEP_00677 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IAEFAFEP_00678 2.2e-34 yaaA S S4 domain protein YaaA
IAEFAFEP_00679 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAEFAFEP_00680 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAEFAFEP_00681 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAEFAFEP_00682 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IAEFAFEP_00683 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IAEFAFEP_00684 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAEFAFEP_00685 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IAEFAFEP_00686 1.2e-74 rplI J Binds to the 23S rRNA
IAEFAFEP_00687 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IAEFAFEP_00688 1.4e-207 lmrP E Major Facilitator Superfamily
IAEFAFEP_00689 1.8e-49
IAEFAFEP_00692 6.8e-130 K response regulator
IAEFAFEP_00693 0.0 vicK 2.7.13.3 T Histidine kinase
IAEFAFEP_00694 3.3e-239 yycH S YycH protein
IAEFAFEP_00695 2.7e-143 yycI S YycH protein
IAEFAFEP_00696 6e-154 vicX 3.1.26.11 S domain protein
IAEFAFEP_00697 3e-208 htrA 3.4.21.107 O serine protease
IAEFAFEP_00698 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAEFAFEP_00699 5.7e-71 K Transcriptional regulator
IAEFAFEP_00700 3.2e-175 malR K Transcriptional regulator, LacI family
IAEFAFEP_00701 1.1e-250 malT G Major Facilitator
IAEFAFEP_00702 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IAEFAFEP_00703 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IAEFAFEP_00704 1.8e-15 natA S ABC transporter, ATP-binding protein
IAEFAFEP_00705 8.8e-16 natA S ABC transporter, ATP-binding protein
IAEFAFEP_00706 9e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IAEFAFEP_00707 1.4e-183 D Alpha beta
IAEFAFEP_00708 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_00709 7.2e-217 patA 2.6.1.1 E Aminotransferase
IAEFAFEP_00710 2.7e-35
IAEFAFEP_00711 0.0 clpL O associated with various cellular activities
IAEFAFEP_00712 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAEFAFEP_00713 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IAEFAFEP_00714 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IAEFAFEP_00715 3.9e-105 yvgN C Aldo keto reductase
IAEFAFEP_00716 1.2e-38 yvgN C Aldo keto reductase
IAEFAFEP_00717 5e-293 glpQ 3.1.4.46 C phosphodiesterase
IAEFAFEP_00718 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
IAEFAFEP_00719 1.6e-189 ybhR V ABC transporter
IAEFAFEP_00720 6.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
IAEFAFEP_00721 2.8e-42 K transcriptional regulator
IAEFAFEP_00722 1.1e-103 2.3.1.128 K acetyltransferase
IAEFAFEP_00723 5.9e-174 coaA 2.7.1.33 F Pantothenic acid kinase
IAEFAFEP_00724 4.9e-131 sptS 2.7.13.3 T Histidine kinase
IAEFAFEP_00725 8e-80 K response regulator
IAEFAFEP_00726 1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
IAEFAFEP_00727 9e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IAEFAFEP_00728 1.8e-105 S polysaccharide biosynthetic process
IAEFAFEP_00729 3.2e-33 wcaB 2.3.1.30 E serine acetyltransferase
IAEFAFEP_00731 5.4e-48 S glycosyl transferase family 2
IAEFAFEP_00732 1.1e-52 MA20_43635 M Capsular polysaccharide synthesis protein
IAEFAFEP_00733 3.5e-66 M Domain of unknown function (DUF4422)
IAEFAFEP_00734 9.9e-146 ydjP I Alpha/beta hydrolase family
IAEFAFEP_00735 5.6e-256 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IAEFAFEP_00736 1.7e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IAEFAFEP_00737 4.2e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IAEFAFEP_00738 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
IAEFAFEP_00739 7.3e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IAEFAFEP_00740 7.6e-211 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IAEFAFEP_00741 7.2e-175 citR K sugar-binding domain protein
IAEFAFEP_00742 1.6e-231 P Sodium:sulfate symporter transmembrane region
IAEFAFEP_00743 1.7e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IAEFAFEP_00744 2.4e-219 frdC 1.3.5.4 C FAD binding domain
IAEFAFEP_00745 1.4e-222 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IAEFAFEP_00746 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
IAEFAFEP_00747 4.6e-183 XK27_09615 S reductase
IAEFAFEP_00748 4.2e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IAEFAFEP_00749 1.8e-79 mleR K LysR family
IAEFAFEP_00750 2e-50 nlhH_1 I Carboxylesterase family
IAEFAFEP_00751 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAEFAFEP_00752 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
IAEFAFEP_00753 2.3e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IAEFAFEP_00754 2e-301 scrB 3.2.1.26 GH32 G invertase
IAEFAFEP_00755 1.9e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
IAEFAFEP_00756 3.2e-164 K LysR substrate binding domain
IAEFAFEP_00757 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IAEFAFEP_00758 1.2e-111
IAEFAFEP_00760 6.2e-266 yjeM E Amino Acid
IAEFAFEP_00761 4.1e-147 ponA V Beta-lactamase enzyme family
IAEFAFEP_00762 5e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IAEFAFEP_00763 1.3e-96
IAEFAFEP_00764 5.9e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IAEFAFEP_00765 4.7e-108 lssY 3.6.1.27 I Acid phosphatase homologues
IAEFAFEP_00766 1.6e-54 S MazG-like family
IAEFAFEP_00767 0.0 L Helicase C-terminal domain protein
IAEFAFEP_00768 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
IAEFAFEP_00769 7.7e-97 K transcriptional regulator
IAEFAFEP_00770 3.8e-166 lmrB EGP Major facilitator Superfamily
IAEFAFEP_00771 8.4e-64 lmrB EGP Major facilitator Superfamily
IAEFAFEP_00773 4.4e-49 tnp L MULE transposase domain
IAEFAFEP_00774 6.1e-29 S Domain of unknown function (DUF4767)
IAEFAFEP_00775 5.4e-44 S Tautomerase enzyme
IAEFAFEP_00776 2.1e-22 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IAEFAFEP_00777 7.8e-120 pnb C nitroreductase
IAEFAFEP_00778 3.2e-83 S Alpha/beta hydrolase family
IAEFAFEP_00779 1.2e-79 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IAEFAFEP_00780 6.2e-24 C reductase
IAEFAFEP_00781 7.7e-46 C Aldo keto reductase
IAEFAFEP_00785 1.2e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IAEFAFEP_00786 0.0 pepN 3.4.11.2 E aminopeptidase
IAEFAFEP_00787 1.7e-60 K Transcriptional regulator
IAEFAFEP_00788 1.3e-24 phaG GT1 I carboxylic ester hydrolase activity
IAEFAFEP_00789 8.1e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IAEFAFEP_00790 4.9e-63 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IAEFAFEP_00792 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00793 7.5e-300 L Recombinase
IAEFAFEP_00794 0.0 L Recombinase zinc beta ribbon domain
IAEFAFEP_00795 8e-35
IAEFAFEP_00796 5.5e-145 M Glycosyl hydrolases family 25
IAEFAFEP_00797 3.6e-70 S Bacteriophage holin family
IAEFAFEP_00798 3.4e-67 S Phage head-tail joining protein
IAEFAFEP_00799 2.8e-42 S Phage gp6-like head-tail connector protein
IAEFAFEP_00800 4.1e-89 S Aminoacyl-tRNA editing domain
IAEFAFEP_00801 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
IAEFAFEP_00803 4.3e-192 nhaC C Na H antiporter NhaC
IAEFAFEP_00804 1.4e-185 S Phosphotransferase system, EIIC
IAEFAFEP_00805 4.6e-23 D mRNA cleavage
IAEFAFEP_00806 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IAEFAFEP_00808 9e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IAEFAFEP_00809 6.7e-66 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IAEFAFEP_00810 6.7e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IAEFAFEP_00811 6.8e-70 ydjP I Alpha/beta hydrolase family
IAEFAFEP_00812 4.4e-106 L Integrase
IAEFAFEP_00813 7.3e-38 M Protein of unknown function (DUF3737)
IAEFAFEP_00814 2.6e-30 4.4.1.8 E Aminotransferase, class I
IAEFAFEP_00815 1.5e-129 1.14.12.17 C Oxidoreductase NAD-binding domain
IAEFAFEP_00816 0.0 ubiB S ABC1 family
IAEFAFEP_00817 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
IAEFAFEP_00818 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IAEFAFEP_00819 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAEFAFEP_00820 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAEFAFEP_00821 5.4e-53
IAEFAFEP_00822 1.4e-43
IAEFAFEP_00823 2.8e-219 3.6.4.12 L DnaB-like helicase C terminal domain
IAEFAFEP_00825 2.1e-13
IAEFAFEP_00826 1.5e-225 aadAT EK Aminotransferase, class I
IAEFAFEP_00827 1.5e-81 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAEFAFEP_00828 5.2e-45 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAEFAFEP_00829 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
IAEFAFEP_00830 1e-103 dedA S SNARE-like domain protein
IAEFAFEP_00831 1.4e-23 S Protein of unknown function (DUF1461)
IAEFAFEP_00832 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IAEFAFEP_00833 2.2e-96 yutD S Protein of unknown function (DUF1027)
IAEFAFEP_00834 1.3e-58 S Calcineurin-like phosphoesterase
IAEFAFEP_00835 1.6e-38 S Calcineurin-like phosphoesterase
IAEFAFEP_00836 2.1e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAEFAFEP_00837 1e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
IAEFAFEP_00839 5e-14
IAEFAFEP_00841 2.3e-15 NU general secretion pathway protein
IAEFAFEP_00842 1.1e-47 comGC U competence protein ComGC
IAEFAFEP_00843 5.6e-157 comGB NU type II secretion system
IAEFAFEP_00844 2.7e-177 comGA NU Type II IV secretion system protein
IAEFAFEP_00845 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
IAEFAFEP_00846 1.9e-83 mltD CBM50 M PFAM NLP P60 protein
IAEFAFEP_00847 3.7e-134 yebC K Transcriptional regulatory protein
IAEFAFEP_00848 3.6e-85
IAEFAFEP_00849 2.2e-185 ccpA K catabolite control protein A
IAEFAFEP_00850 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IAEFAFEP_00851 4.9e-70
IAEFAFEP_00852 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAEFAFEP_00853 2e-155 ykuT M mechanosensitive ion channel
IAEFAFEP_00854 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IAEFAFEP_00855 4.4e-94 S Phosphoesterase
IAEFAFEP_00856 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAEFAFEP_00857 6.3e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IAEFAFEP_00858 3e-93 yslB S Protein of unknown function (DUF2507)
IAEFAFEP_00859 1.2e-225 clcA_2 P Chloride transporter, ClC family
IAEFAFEP_00860 1e-53 trxA O Belongs to the thioredoxin family
IAEFAFEP_00861 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IAEFAFEP_00862 4.7e-91 cvpA S Colicin V production protein
IAEFAFEP_00863 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAEFAFEP_00864 5.7e-33 yrzB S Belongs to the UPF0473 family
IAEFAFEP_00865 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAEFAFEP_00866 1.2e-42 yrzL S Belongs to the UPF0297 family
IAEFAFEP_00867 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAEFAFEP_00868 4.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IAEFAFEP_00869 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IAEFAFEP_00870 5.5e-42 yajC U Preprotein translocase
IAEFAFEP_00871 2.2e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
IAEFAFEP_00872 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IAEFAFEP_00873 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IAEFAFEP_00874 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAEFAFEP_00875 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAEFAFEP_00876 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
IAEFAFEP_00877 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAEFAFEP_00878 5.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
IAEFAFEP_00879 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAEFAFEP_00880 1.8e-96 ymfM S Helix-turn-helix domain
IAEFAFEP_00881 1.7e-251 ymfH S Peptidase M16
IAEFAFEP_00882 1.5e-231 ymfF S Peptidase M16 inactive domain protein
IAEFAFEP_00883 2.4e-161 aatB ET ABC transporter substrate-binding protein
IAEFAFEP_00884 4.8e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAEFAFEP_00885 1.4e-108 glnP P ABC transporter permease
IAEFAFEP_00886 6.6e-93 mreD M rod shape-determining protein MreD
IAEFAFEP_00887 1.4e-145 mreC M Involved in formation and maintenance of cell shape
IAEFAFEP_00888 1.9e-181 mreB D cell shape determining protein MreB
IAEFAFEP_00889 3.3e-115 radC L DNA repair protein
IAEFAFEP_00890 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IAEFAFEP_00891 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IAEFAFEP_00892 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAEFAFEP_00895 4.1e-90 L Probable transposase
IAEFAFEP_00896 3e-28 EGP Major Facilitator Superfamily
IAEFAFEP_00897 1.6e-44 EGP Major Facilitator Superfamily
IAEFAFEP_00898 1.6e-69 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IAEFAFEP_00899 6.9e-58 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IAEFAFEP_00900 3.5e-15 C Flavodoxin
IAEFAFEP_00901 4.3e-27 GM NmrA-like family
IAEFAFEP_00902 5.1e-19 S NAD(P)H dehydrogenase (quinone) activity
IAEFAFEP_00903 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00904 2.7e-216 L transposase, IS605 OrfB family
IAEFAFEP_00905 9.8e-77
IAEFAFEP_00906 1.6e-102 gbuC E glycine betaine
IAEFAFEP_00907 4.8e-98 proW E glycine betaine
IAEFAFEP_00908 1.1e-153 gbuA 3.6.1.1, 3.6.3.32 E glycine betaine
IAEFAFEP_00909 5.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
IAEFAFEP_00910 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IAEFAFEP_00911 3.5e-38 S Cytochrome B5
IAEFAFEP_00912 1.7e-14 yfjR K Psort location Cytoplasmic, score
IAEFAFEP_00914 6.5e-11 S Domain of unknown function (DUF4811)
IAEFAFEP_00915 8.7e-40 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_00916 8.9e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
IAEFAFEP_00917 4.3e-217 yceI EGP Major facilitator Superfamily
IAEFAFEP_00918 2.6e-54 tnp2PF3 L Transposase
IAEFAFEP_00919 8.3e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IAEFAFEP_00920 4.1e-21 L Transposase
IAEFAFEP_00921 4.1e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IAEFAFEP_00922 1.6e-45 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
IAEFAFEP_00923 5.6e-33 copZ P Heavy-metal-associated domain
IAEFAFEP_00924 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IAEFAFEP_00925 1.2e-64
IAEFAFEP_00926 6.3e-140 L reverse transcriptase
IAEFAFEP_00927 1.4e-189 L Transposase and inactivated derivatives, IS30 family
IAEFAFEP_00928 4.1e-19
IAEFAFEP_00929 9.8e-30
IAEFAFEP_00930 4.4e-42 S dextransucrase activity
IAEFAFEP_00931 2.4e-192 yegU O ADP-ribosylglycohydrolase
IAEFAFEP_00932 2.3e-251 F Belongs to the purine-cytosine permease (2.A.39) family
IAEFAFEP_00933 7.2e-169 G Belongs to the carbohydrate kinase PfkB family
IAEFAFEP_00934 8.2e-48 L Transposase DDE domain group 1
IAEFAFEP_00936 4.6e-40
IAEFAFEP_00937 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
IAEFAFEP_00938 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAEFAFEP_00939 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
IAEFAFEP_00940 6.4e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IAEFAFEP_00941 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAEFAFEP_00943 5.5e-26 S YjcQ protein
IAEFAFEP_00944 1.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAEFAFEP_00945 5.3e-133 S Membrane
IAEFAFEP_00946 1.3e-75 4.4.1.5 E Glyoxalase
IAEFAFEP_00947 4.5e-85 yueI S Protein of unknown function (DUF1694)
IAEFAFEP_00948 4.9e-235 rarA L recombination factor protein RarA
IAEFAFEP_00950 2.3e-81 usp6 T universal stress protein
IAEFAFEP_00951 8.4e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IAEFAFEP_00952 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IAEFAFEP_00953 5.8e-180 S Protein of unknown function (DUF2785)
IAEFAFEP_00955 5.8e-222 rodA D Belongs to the SEDS family
IAEFAFEP_00956 7.9e-32 S Protein of unknown function (DUF2969)
IAEFAFEP_00957 2.6e-183 mbl D Cell shape determining protein MreB Mrl
IAEFAFEP_00958 1.9e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
IAEFAFEP_00959 2.8e-29 S Protein of unknown function (DUF1146)
IAEFAFEP_00960 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IAEFAFEP_00961 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAEFAFEP_00962 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAEFAFEP_00963 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAEFAFEP_00964 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAEFAFEP_00965 2.6e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAEFAFEP_00966 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAEFAFEP_00967 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
IAEFAFEP_00968 5.4e-218 pyrP F Permease
IAEFAFEP_00969 4.2e-125 yibF S overlaps another CDS with the same product name
IAEFAFEP_00970 1.7e-183 yibE S overlaps another CDS with the same product name
IAEFAFEP_00971 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAEFAFEP_00972 1.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAEFAFEP_00973 9.8e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IAEFAFEP_00974 3.2e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IAEFAFEP_00975 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAEFAFEP_00976 3.2e-109 tdk 2.7.1.21 F thymidine kinase
IAEFAFEP_00977 3.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IAEFAFEP_00978 1.3e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IAEFAFEP_00979 2.8e-48
IAEFAFEP_00980 1.9e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAEFAFEP_00981 2.8e-193 ampC V Beta-lactamase
IAEFAFEP_00982 0.0 yfiC V ABC transporter
IAEFAFEP_00983 0.0 lmrA V ABC transporter, ATP-binding protein
IAEFAFEP_00984 1.8e-78 K Winged helix DNA-binding domain
IAEFAFEP_00985 2.3e-07
IAEFAFEP_00987 1e-56
IAEFAFEP_00989 2.1e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IAEFAFEP_00990 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAEFAFEP_00991 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
IAEFAFEP_00992 1.8e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IAEFAFEP_00993 1.6e-85 K GNAT family
IAEFAFEP_00995 1.1e-50 L Helix-turn-helix domain
IAEFAFEP_00996 6.2e-85 L hmm pf00665
IAEFAFEP_00997 5.2e-35 L Transposase and inactivated derivatives, IS30 family
IAEFAFEP_00998 1.2e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
IAEFAFEP_00999 0.0 cadA 3.6.3.3, 3.6.3.5 P Cadmium transporter
IAEFAFEP_01000 1.3e-162 L Transposase and inactivated derivatives, IS30 family
IAEFAFEP_01001 6.2e-218 lacS G Transporter
IAEFAFEP_01002 2.3e-83 lacR K Transcriptional regulator
IAEFAFEP_01003 7.7e-171 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IAEFAFEP_01004 1.9e-224 emrY EGP Major facilitator Superfamily
IAEFAFEP_01005 2.1e-61 3.2.1.23 S Domain of unknown function DUF302
IAEFAFEP_01006 9.8e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAEFAFEP_01007 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
IAEFAFEP_01008 5.1e-87 uspA T Belongs to the universal stress protein A family
IAEFAFEP_01009 1.3e-170 L Integrase core domain
IAEFAFEP_01011 6.3e-271 nylA 3.5.1.4 J Belongs to the amidase family
IAEFAFEP_01012 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_01013 1.3e-75 S Homeodomain-like domain
IAEFAFEP_01015 5.9e-98 D Cellulose biosynthesis protein BcsQ
IAEFAFEP_01016 2.7e-97 xerC L Phage integrase, N-terminal SAM-like domain
IAEFAFEP_01018 2.6e-255 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IAEFAFEP_01019 1.3e-31 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01020 4.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAEFAFEP_01021 5e-162 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IAEFAFEP_01022 3e-184 fruR3 K Transcriptional regulator, LacI family
IAEFAFEP_01023 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IAEFAFEP_01024 8.9e-83 F Hydrolase, NUDIX family
IAEFAFEP_01025 1.4e-212 S Type IV secretion-system coupling protein DNA-binding domain
IAEFAFEP_01026 0.0 tetP J elongation factor G
IAEFAFEP_01027 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IAEFAFEP_01028 2.7e-111 ypsA S Belongs to the UPF0398 family
IAEFAFEP_01029 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IAEFAFEP_01030 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IAEFAFEP_01031 3.7e-160 EG EamA-like transporter family
IAEFAFEP_01032 1.8e-192 C Aldo keto reductase family protein
IAEFAFEP_01033 1.3e-121 ypuA S Protein of unknown function (DUF1002)
IAEFAFEP_01034 4.7e-134 dnaD L DnaD domain protein
IAEFAFEP_01035 1.7e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IAEFAFEP_01036 1.6e-88 ypmB S Protein conserved in bacteria
IAEFAFEP_01037 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IAEFAFEP_01038 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IAEFAFEP_01039 2.4e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IAEFAFEP_01040 1.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IAEFAFEP_01041 4.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IAEFAFEP_01042 1.5e-93 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01043 2.3e-103 pstA P Phosphate transport system permease protein PstA
IAEFAFEP_01045 1.8e-75 pstC P probably responsible for the translocation of the substrate across the membrane
IAEFAFEP_01046 9e-92 pstS P Phosphate
IAEFAFEP_01047 2.4e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IAEFAFEP_01048 4.5e-154 yitU 3.1.3.104 S hydrolase
IAEFAFEP_01049 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IAEFAFEP_01050 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAEFAFEP_01051 8.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IAEFAFEP_01052 1.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IAEFAFEP_01053 3.3e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IAEFAFEP_01054 6.6e-56 ycsI S Protein of unknown function (DUF1445)
IAEFAFEP_01055 2e-84 L Belongs to the 'phage' integrase family
IAEFAFEP_01056 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IAEFAFEP_01057 1.3e-260 yfnA E Amino Acid
IAEFAFEP_01058 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IAEFAFEP_01059 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAEFAFEP_01060 3.5e-39 ylqC S Belongs to the UPF0109 family
IAEFAFEP_01061 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IAEFAFEP_01062 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
IAEFAFEP_01063 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IAEFAFEP_01064 5.5e-153 pstA P Phosphate transport system permease protein PstA
IAEFAFEP_01065 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
IAEFAFEP_01066 5.1e-159 pstS P Phosphate
IAEFAFEP_01067 9.8e-129 K Transcriptional regulatory protein, C-terminal domain protein
IAEFAFEP_01068 1.7e-23
IAEFAFEP_01069 7.6e-108 T Calcineurin-like phosphoesterase superfamily domain
IAEFAFEP_01070 4.1e-213 G Major Facilitator Superfamily
IAEFAFEP_01071 1e-120 mleP3 S Membrane transport protein
IAEFAFEP_01072 1.1e-52 trxA O Belongs to the thioredoxin family
IAEFAFEP_01073 4.4e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IAEFAFEP_01074 1e-183 EG GntP family permease
IAEFAFEP_01075 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IAEFAFEP_01076 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IAEFAFEP_01077 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
IAEFAFEP_01078 2.2e-36 tnp L MULE transposase domain
IAEFAFEP_01079 1.5e-46 ubiE Q Methyltransferase domain
IAEFAFEP_01080 1.2e-21
IAEFAFEP_01081 2.9e-50 4.4.1.8 E Aminotransferase, class I
IAEFAFEP_01082 2e-34 4.4.1.8 E Aminotransferase, class I
IAEFAFEP_01083 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_01084 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAEFAFEP_01086 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01087 3.5e-83 glcU U sugar transport
IAEFAFEP_01088 3.5e-87 galR K Transcriptional regulator
IAEFAFEP_01089 4.1e-21 L Transposase
IAEFAFEP_01090 9.5e-72 macB_3 V FtsX-like permease family
IAEFAFEP_01091 1.6e-90 S PAS domain
IAEFAFEP_01092 2.2e-30 E IrrE N-terminal-like domain
IAEFAFEP_01109 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IAEFAFEP_01110 2.2e-45 IQ reductase
IAEFAFEP_01111 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAEFAFEP_01112 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_01113 3.3e-155 L COG2801 Transposase and inactivated derivatives
IAEFAFEP_01114 6.9e-33 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAEFAFEP_01115 3.5e-30
IAEFAFEP_01117 4.1e-214 I transferase activity, transferring acyl groups other than amino-acyl groups
IAEFAFEP_01119 3.6e-94 padC Q Phenolic acid decarboxylase
IAEFAFEP_01120 8.3e-99 padR K Virulence activator alpha C-term
IAEFAFEP_01121 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
IAEFAFEP_01122 8e-42 S SNARE associated Golgi protein
IAEFAFEP_01123 1e-237 N Uncharacterized conserved protein (DUF2075)
IAEFAFEP_01124 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAEFAFEP_01126 2.3e-254 yifK E Amino acid permease
IAEFAFEP_01128 2.7e-268 pipD E Dipeptidase
IAEFAFEP_01129 1.2e-163 endA F DNA RNA non-specific endonuclease
IAEFAFEP_01130 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IAEFAFEP_01131 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAEFAFEP_01132 6.3e-154 S Alpha/beta hydrolase of unknown function (DUF915)
IAEFAFEP_01134 9.2e-228
IAEFAFEP_01135 1e-193 V Beta-lactamase
IAEFAFEP_01136 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IAEFAFEP_01137 2.9e-123 S membrane transporter protein
IAEFAFEP_01138 4.7e-178 S AI-2E family transporter
IAEFAFEP_01139 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
IAEFAFEP_01140 4.1e-161 rssA S Phospholipase, patatin family
IAEFAFEP_01141 4.4e-169 K LysR substrate binding domain
IAEFAFEP_01142 0.0 1.3.5.4 C FAD binding domain
IAEFAFEP_01143 1.3e-73 S Domain of unknown function (DUF4352)
IAEFAFEP_01144 1.3e-112 yicL EG EamA-like transporter family
IAEFAFEP_01145 3.3e-64
IAEFAFEP_01148 1.1e-29
IAEFAFEP_01149 4.1e-68 S pyridoxamine 5-phosphate
IAEFAFEP_01150 2.8e-179 yobV1 K WYL domain
IAEFAFEP_01151 1.3e-243 XK27_08635 S UPF0210 protein
IAEFAFEP_01152 2.5e-40 gcvR T Belongs to the UPF0237 family
IAEFAFEP_01153 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAEFAFEP_01154 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IAEFAFEP_01155 4.7e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IAEFAFEP_01156 1.7e-218 G Transporter, major facilitator family protein
IAEFAFEP_01157 1.3e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IAEFAFEP_01158 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAEFAFEP_01159 5.5e-57 ydiI Q Thioesterase superfamily
IAEFAFEP_01160 1.2e-132 L hmm pf00665
IAEFAFEP_01161 1.6e-61 L Helix-turn-helix domain
IAEFAFEP_01162 3.3e-166 L PFAM Integrase catalytic region
IAEFAFEP_01163 1.1e-23 L Helix-turn-helix domain
IAEFAFEP_01164 9.2e-21 L transposase, IS605 OrfB family
IAEFAFEP_01165 1.5e-93 tdh 1.1.1.14 C Zinc-binding dehydrogenase
IAEFAFEP_01166 8.6e-259 guaD 3.5.4.3 F Amidohydrolase family
IAEFAFEP_01167 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAEFAFEP_01169 7.8e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
IAEFAFEP_01170 6.2e-75 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IAEFAFEP_01171 3.6e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
IAEFAFEP_01172 1.1e-89 rmeB K transcriptional regulator, MerR family
IAEFAFEP_01173 7.2e-133 ybbM S Uncharacterised protein family (UPF0014)
IAEFAFEP_01174 6.4e-111 ybbL S ABC transporter, ATP-binding protein
IAEFAFEP_01175 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IAEFAFEP_01176 5.9e-100 G Protein of unknown function (DUF4038)
IAEFAFEP_01177 3.7e-184 C Oxidoreductase
IAEFAFEP_01178 2.1e-89 deoR K sugar-binding domain protein
IAEFAFEP_01179 2.4e-114 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IAEFAFEP_01180 1.1e-160 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IAEFAFEP_01181 1.6e-195 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAEFAFEP_01182 3.2e-89 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAEFAFEP_01183 5.3e-08 L PFAM Integrase catalytic
IAEFAFEP_01184 7.7e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IAEFAFEP_01185 5.3e-167 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IAEFAFEP_01186 4.8e-84 csm5 L RAMP superfamily
IAEFAFEP_01187 1e-77 csm4 L CRISPR-associated RAMP protein, Csm4 family
IAEFAFEP_01188 1.6e-80 csm3 L RAMP superfamily
IAEFAFEP_01189 3.5e-19 csm2 L CRISPR-associated protein Csm2 family
IAEFAFEP_01190 2.2e-225 csm1 S CRISPR-associated protein Csm1 family
IAEFAFEP_01191 4e-51 cas6 S Pfam:DUF2276
IAEFAFEP_01192 2.2e-56 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IAEFAFEP_01193 0.0 L Type III restriction enzyme, res subunit
IAEFAFEP_01195 2.4e-101 K DNA-templated transcription, initiation
IAEFAFEP_01196 1.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAEFAFEP_01197 2.3e-30 arsD S Arsenical resistance operon trans-acting repressor ArsD
IAEFAFEP_01198 1.8e-232 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAEFAFEP_01199 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
IAEFAFEP_01200 1.8e-56 arsR K Helix-turn-helix domain
IAEFAFEP_01201 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
IAEFAFEP_01202 4.2e-116 arcD S C4-dicarboxylate anaerobic carrier
IAEFAFEP_01203 2e-22 S Phage capsid family
IAEFAFEP_01205 2.8e-93 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IAEFAFEP_01206 3.6e-32 higA K Helix-turn-helix XRE-family like proteins
IAEFAFEP_01207 1.1e-30 S Sugar efflux transporter for intercellular exchange
IAEFAFEP_01208 1.9e-134 S interspecies interaction between organisms
IAEFAFEP_01210 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IAEFAFEP_01211 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAEFAFEP_01212 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IAEFAFEP_01213 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAEFAFEP_01214 5.8e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAEFAFEP_01215 4.6e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAEFAFEP_01216 2.8e-61 rplQ J Ribosomal protein L17
IAEFAFEP_01217 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAEFAFEP_01218 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAEFAFEP_01219 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAEFAFEP_01220 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IAEFAFEP_01221 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAEFAFEP_01222 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IAEFAFEP_01223 1e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IAEFAFEP_01224 2.1e-65 rplO J Binds to the 23S rRNA
IAEFAFEP_01225 2.5e-23 rpmD J Ribosomal protein L30
IAEFAFEP_01226 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAEFAFEP_01227 5.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAEFAFEP_01228 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAEFAFEP_01229 3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAEFAFEP_01230 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAEFAFEP_01231 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAEFAFEP_01232 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAEFAFEP_01233 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAEFAFEP_01234 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAEFAFEP_01235 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
IAEFAFEP_01236 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAEFAFEP_01237 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAEFAFEP_01238 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAEFAFEP_01239 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAEFAFEP_01240 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAEFAFEP_01241 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IAEFAFEP_01242 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
IAEFAFEP_01243 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAEFAFEP_01244 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IAEFAFEP_01245 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAEFAFEP_01246 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IAEFAFEP_01247 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAEFAFEP_01248 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
IAEFAFEP_01249 3.7e-213 ykiI
IAEFAFEP_01250 5.6e-135 puuD S peptidase C26
IAEFAFEP_01251 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAEFAFEP_01252 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAEFAFEP_01253 5.8e-106 K Bacterial regulatory proteins, tetR family
IAEFAFEP_01254 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IAEFAFEP_01255 4.8e-79 ctsR K Belongs to the CtsR family
IAEFAFEP_01256 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
IAEFAFEP_01257 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
IAEFAFEP_01258 2.7e-120 J 2'-5' RNA ligase superfamily
IAEFAFEP_01260 7.7e-39 S ABC-type cobalt transport system, permease component
IAEFAFEP_01261 1.2e-16 S ABC-type cobalt transport system, permease component
IAEFAFEP_01262 2.2e-43 K helix_turn_helix multiple antibiotic resistance protein
IAEFAFEP_01263 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
IAEFAFEP_01265 8.8e-88
IAEFAFEP_01266 1e-69 S Asp23 family, cell envelope-related function
IAEFAFEP_01267 6e-12 S Transglycosylase associated protein
IAEFAFEP_01268 3.8e-16
IAEFAFEP_01270 4e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01271 1e-15
IAEFAFEP_01272 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IAEFAFEP_01273 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IAEFAFEP_01274 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IAEFAFEP_01275 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IAEFAFEP_01276 1.5e-253 yifK E Amino acid permease
IAEFAFEP_01277 3.2e-289 clcA P chloride
IAEFAFEP_01278 4.5e-33 secG U Preprotein translocase
IAEFAFEP_01279 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IAEFAFEP_01280 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IAEFAFEP_01281 7.9e-108 yxjI
IAEFAFEP_01282 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAEFAFEP_01283 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IAEFAFEP_01284 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IAEFAFEP_01285 1.6e-88 K Acetyltransferase (GNAT) domain
IAEFAFEP_01286 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
IAEFAFEP_01287 5.7e-166 murB 1.3.1.98 M Cell wall formation
IAEFAFEP_01288 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAEFAFEP_01289 9.1e-116 ybbR S YbbR-like protein
IAEFAFEP_01290 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAEFAFEP_01291 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IAEFAFEP_01292 1.5e-52
IAEFAFEP_01293 1.2e-210 oatA I Acyltransferase
IAEFAFEP_01294 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IAEFAFEP_01295 1.3e-68 lytE M Lysin motif
IAEFAFEP_01296 2.7e-159 MA20_14895 S Conserved hypothetical protein 698
IAEFAFEP_01297 9.6e-169 K LysR substrate binding domain
IAEFAFEP_01298 1.9e-130 manA 5.3.1.8 G mannose-6-phosphate isomerase
IAEFAFEP_01299 6.6e-148 yitS S EDD domain protein, DegV family
IAEFAFEP_01300 6.5e-90 racA K Domain of unknown function (DUF1836)
IAEFAFEP_01301 2.3e-181 yfeX P Peroxidase
IAEFAFEP_01302 4.5e-180 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IAEFAFEP_01303 3.5e-114 manY G PTS system
IAEFAFEP_01304 3e-170 manN G system, mannose fructose sorbose family IID component
IAEFAFEP_01305 1.6e-57 S Domain of unknown function (DUF956)
IAEFAFEP_01307 2.8e-131 K response regulator
IAEFAFEP_01308 1.3e-250 yclK 2.7.13.3 T Histidine kinase
IAEFAFEP_01309 3.8e-151 glcU U sugar transport
IAEFAFEP_01313 3.1e-33
IAEFAFEP_01314 7.1e-33 L Belongs to the 'phage' integrase family
IAEFAFEP_01317 5.3e-17 mleP3 S Membrane transport protein
IAEFAFEP_01318 9.7e-118 yplB S Ankyrin repeats (3 copies)
IAEFAFEP_01319 4.9e-103 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAEFAFEP_01320 4.8e-86 yrjD S LUD domain
IAEFAFEP_01321 1.4e-244 lutB C 4Fe-4S dicluster domain
IAEFAFEP_01322 5.6e-122 lutA C Cysteine-rich domain
IAEFAFEP_01323 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IAEFAFEP_01324 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAEFAFEP_01325 2.4e-37 ynzC S UPF0291 protein
IAEFAFEP_01326 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
IAEFAFEP_01327 3.3e-115 plsC 2.3.1.51 I Acyltransferase
IAEFAFEP_01328 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
IAEFAFEP_01329 2.3e-47 yazA L GIY-YIG catalytic domain protein
IAEFAFEP_01330 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
IAEFAFEP_01331 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAEFAFEP_01332 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IAEFAFEP_01333 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IAEFAFEP_01334 5.9e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAEFAFEP_01335 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
IAEFAFEP_01336 1.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IAEFAFEP_01337 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IAEFAFEP_01338 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAEFAFEP_01339 4.1e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
IAEFAFEP_01340 2.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IAEFAFEP_01341 2.6e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAEFAFEP_01342 1.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAEFAFEP_01343 4.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IAEFAFEP_01344 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IAEFAFEP_01345 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
IAEFAFEP_01346 8.3e-224 nusA K Participates in both transcription termination and antitermination
IAEFAFEP_01347 2.4e-47 ylxR K Protein of unknown function (DUF448)
IAEFAFEP_01348 1.6e-49 ylxQ J ribosomal protein
IAEFAFEP_01349 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAEFAFEP_01350 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAEFAFEP_01351 5.7e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAEFAFEP_01352 5e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IAEFAFEP_01353 1.1e-248 EGP Major facilitator Superfamily
IAEFAFEP_01354 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01356 1.7e-165 GK ROK family
IAEFAFEP_01357 1.1e-40
IAEFAFEP_01358 4.2e-80 copY K Copper transport repressor CopY TcrY
IAEFAFEP_01359 3e-72 ybeZ T Phosphate starvation-inducible protein PhoH
IAEFAFEP_01360 1e-56 trxA1 O Belongs to the thioredoxin family
IAEFAFEP_01361 2.3e-142 terC P membrane
IAEFAFEP_01362 5.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IAEFAFEP_01363 1.8e-167 corA P CorA-like Mg2+ transporter protein
IAEFAFEP_01364 2.6e-231 pbuX F xanthine permease
IAEFAFEP_01365 1e-151 qorB 1.6.5.2 GM NmrA-like family
IAEFAFEP_01366 2.5e-126 pgm3 G phosphoglycerate mutase family
IAEFAFEP_01367 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IAEFAFEP_01368 2e-85
IAEFAFEP_01369 7.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IAEFAFEP_01370 8.8e-101 dps P Belongs to the Dps family
IAEFAFEP_01371 1.1e-31 copZ P Heavy-metal-associated domain
IAEFAFEP_01372 9.7e-292 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IAEFAFEP_01373 1.3e-19 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IAEFAFEP_01374 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IAEFAFEP_01375 2.2e-179 iunH2 3.2.2.1 F nucleoside hydrolase
IAEFAFEP_01376 2.7e-100 S ABC-type cobalt transport system, permease component
IAEFAFEP_01377 2.1e-255 cbiO1 S ABC transporter, ATP-binding protein
IAEFAFEP_01378 5.7e-115 P Cobalt transport protein
IAEFAFEP_01379 1.2e-16 yvlA
IAEFAFEP_01380 0.0 yjcE P Sodium proton antiporter
IAEFAFEP_01381 4e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
IAEFAFEP_01382 7.8e-73 O OsmC-like protein
IAEFAFEP_01383 4.1e-186 D Alpha beta
IAEFAFEP_01384 8.4e-75 K Transcriptional regulator
IAEFAFEP_01385 4.5e-160
IAEFAFEP_01386 6.6e-20
IAEFAFEP_01387 2.1e-59
IAEFAFEP_01388 3.1e-75 uspA T universal stress protein
IAEFAFEP_01390 9.7e-130 qmcA O prohibitin homologues
IAEFAFEP_01391 5.5e-245 glpT G Major Facilitator Superfamily
IAEFAFEP_01392 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAEFAFEP_01393 2.3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
IAEFAFEP_01394 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAEFAFEP_01395 1.8e-126 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAEFAFEP_01396 6.2e-59 L Helix-turn-helix domain
IAEFAFEP_01397 4e-125 O Bacterial dnaA protein
IAEFAFEP_01398 4.7e-219 L Integrase core domain
IAEFAFEP_01399 7.3e-100 cfa 2.1.1.317, 2.1.1.79 M synthase
IAEFAFEP_01400 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
IAEFAFEP_01401 6.3e-145 L 4.5 Transposon and IS
IAEFAFEP_01402 3.3e-29 L Transposase
IAEFAFEP_01403 1.2e-123 S Membrane
IAEFAFEP_01404 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IAEFAFEP_01405 0.0 pepF E oligoendopeptidase F
IAEFAFEP_01406 1.7e-179 K helix_turn _helix lactose operon repressor
IAEFAFEP_01407 1.3e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IAEFAFEP_01408 1.9e-77 K AsnC family
IAEFAFEP_01409 1.4e-81 uspA T universal stress protein
IAEFAFEP_01410 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAEFAFEP_01411 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAEFAFEP_01412 5.1e-207 yeaN P Transporter, major facilitator family protein
IAEFAFEP_01413 1.5e-74 S 3-demethylubiquinone-9 3-methyltransferase
IAEFAFEP_01414 9.2e-83 nrdI F Belongs to the NrdI family
IAEFAFEP_01415 3.6e-252 yhdP S Transporter associated domain
IAEFAFEP_01416 3e-90 GM epimerase
IAEFAFEP_01417 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
IAEFAFEP_01418 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IAEFAFEP_01419 7.8e-266 pipD E Dipeptidase
IAEFAFEP_01420 9.4e-130
IAEFAFEP_01421 2.7e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAEFAFEP_01422 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
IAEFAFEP_01423 4.3e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IAEFAFEP_01424 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IAEFAFEP_01426 1.4e-281 yjeM E Amino Acid
IAEFAFEP_01427 1.7e-187 K helix_turn _helix lactose operon repressor
IAEFAFEP_01428 9.8e-261 G PTS system Galactitol-specific IIC component
IAEFAFEP_01429 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAEFAFEP_01430 4.3e-164 L Initiator Replication protein
IAEFAFEP_01434 6.7e-63 recD 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAEFAFEP_01435 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01436 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IAEFAFEP_01437 1.1e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IAEFAFEP_01438 1.6e-61
IAEFAFEP_01439 2.5e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IAEFAFEP_01440 1.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAEFAFEP_01441 0.0 dnaK O Heat shock 70 kDa protein
IAEFAFEP_01442 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IAEFAFEP_01443 2.8e-54 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAEFAFEP_01444 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IAEFAFEP_01445 1.9e-50 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IAEFAFEP_01446 8.3e-167 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
IAEFAFEP_01447 6.4e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAEFAFEP_01448 2.2e-108 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IAEFAFEP_01449 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAEFAFEP_01450 2.2e-102 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IAEFAFEP_01451 1.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAEFAFEP_01452 5.9e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAEFAFEP_01453 5.6e-141 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IAEFAFEP_01454 4.2e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAEFAFEP_01455 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IAEFAFEP_01456 5.1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAEFAFEP_01457 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IAEFAFEP_01458 3.3e-09
IAEFAFEP_01459 1.9e-112 3.1.3.73 G phosphoglycerate mutase
IAEFAFEP_01460 3.2e-112 C aldo keto reductase
IAEFAFEP_01461 8.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAEFAFEP_01462 4.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_01463 2.7e-268 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IAEFAFEP_01464 7.9e-79 K 2 iron, 2 sulfur cluster binding
IAEFAFEP_01465 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IAEFAFEP_01466 9.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IAEFAFEP_01467 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IAEFAFEP_01468 3.4e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAEFAFEP_01469 7.2e-54 C FMN binding
IAEFAFEP_01470 1.7e-28 T His Kinase A (phosphoacceptor) domain
IAEFAFEP_01471 7.8e-52 T Transcriptional regulatory protein, C terminal
IAEFAFEP_01472 1.2e-15 S ABC-type transport system involved in multi-copper enzyme maturation permease component
IAEFAFEP_01473 3.7e-221 iscS 2.8.1.7 E Aminotransferase class V
IAEFAFEP_01474 4.7e-123 srtA 3.4.22.70 M sortase family
IAEFAFEP_01475 3.3e-29 mdtG EGP Major facilitator Superfamily
IAEFAFEP_01476 6e-41 rpmE2 J Ribosomal protein L31
IAEFAFEP_01477 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAEFAFEP_01478 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IAEFAFEP_01479 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IAEFAFEP_01480 5.5e-74 ywiB S Domain of unknown function (DUF1934)
IAEFAFEP_01481 4.3e-266 ywfO S HD domain protein
IAEFAFEP_01482 4.8e-143 yxeH S hydrolase
IAEFAFEP_01483 3e-32
IAEFAFEP_01484 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAEFAFEP_01485 7.3e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAEFAFEP_01486 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IAEFAFEP_01487 3.2e-128 znuB U ABC 3 transport family
IAEFAFEP_01488 5.4e-95 fhuC P ABC transporter
IAEFAFEP_01489 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
IAEFAFEP_01490 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAEFAFEP_01491 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IAEFAFEP_01492 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAEFAFEP_01493 1.8e-147 tatD L hydrolase, TatD family
IAEFAFEP_01494 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAEFAFEP_01495 9.5e-163 yunF F Protein of unknown function DUF72
IAEFAFEP_01496 5.3e-212 norA EGP Major facilitator Superfamily
IAEFAFEP_01497 4.4e-129 cobB K SIR2 family
IAEFAFEP_01498 3.2e-186
IAEFAFEP_01499 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IAEFAFEP_01500 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAEFAFEP_01501 0.0 helD 3.6.4.12 L DNA helicase
IAEFAFEP_01502 1.2e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IAEFAFEP_01503 7.4e-155 metQ_4 P Belongs to the nlpA lipoprotein family
IAEFAFEP_01504 1.4e-168 D nuclear chromosome segregation
IAEFAFEP_01505 3.7e-258 dtpT U amino acid peptide transporter
IAEFAFEP_01506 2.1e-165 yjjH S Calcineurin-like phosphoesterase
IAEFAFEP_01509 1.1e-115
IAEFAFEP_01510 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IAEFAFEP_01511 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
IAEFAFEP_01512 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAEFAFEP_01513 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IAEFAFEP_01514 0.0 yhgF K Tex-like protein N-terminal domain protein
IAEFAFEP_01515 2.4e-83 ydcK S Belongs to the SprT family
IAEFAFEP_01517 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IAEFAFEP_01518 8.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IAEFAFEP_01519 2.3e-168 mleP2 S Sodium Bile acid symporter family
IAEFAFEP_01520 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAEFAFEP_01521 1.3e-167 I alpha/beta hydrolase fold
IAEFAFEP_01522 6.8e-264 pepC 3.4.22.40 E Peptidase C1-like family
IAEFAFEP_01523 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
IAEFAFEP_01524 1.3e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAEFAFEP_01525 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
IAEFAFEP_01526 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IAEFAFEP_01527 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAEFAFEP_01528 2.7e-205 yacL S domain protein
IAEFAFEP_01529 9.6e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAEFAFEP_01530 7.8e-100 ywlG S Belongs to the UPF0340 family
IAEFAFEP_01531 6.5e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IAEFAFEP_01532 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAEFAFEP_01533 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAEFAFEP_01534 1.1e-104 sigH K Belongs to the sigma-70 factor family
IAEFAFEP_01535 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IAEFAFEP_01536 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IAEFAFEP_01537 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
IAEFAFEP_01538 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAEFAFEP_01539 5.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IAEFAFEP_01540 1.7e-243 steT E amino acid
IAEFAFEP_01541 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAEFAFEP_01542 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IAEFAFEP_01543 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
IAEFAFEP_01544 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IAEFAFEP_01545 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IAEFAFEP_01546 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAEFAFEP_01547 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IAEFAFEP_01548 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
IAEFAFEP_01549 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAEFAFEP_01550 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAEFAFEP_01551 2e-35 nrdH O Glutaredoxin
IAEFAFEP_01552 1.8e-79 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IAEFAFEP_01554 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAEFAFEP_01555 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAEFAFEP_01556 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAEFAFEP_01557 1.2e-20 S Protein of unknown function (DUF2508)
IAEFAFEP_01558 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAEFAFEP_01559 1.2e-52 yaaQ S Cyclic-di-AMP receptor
IAEFAFEP_01560 4.9e-193 holB 2.7.7.7 L DNA polymerase III
IAEFAFEP_01561 1.5e-55 yabA L Involved in initiation control of chromosome replication
IAEFAFEP_01562 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAEFAFEP_01563 2.8e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
IAEFAFEP_01564 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAEFAFEP_01565 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAEFAFEP_01566 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IAEFAFEP_01567 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IAEFAFEP_01568 6.7e-148 KT YcbB domain
IAEFAFEP_01569 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAEFAFEP_01570 3.2e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IAEFAFEP_01571 8.2e-240 arcA 3.5.3.6 E Arginine
IAEFAFEP_01572 8.6e-257 E Arginine ornithine antiporter
IAEFAFEP_01573 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IAEFAFEP_01574 7.6e-216 arcT 2.6.1.1 E Aminotransferase
IAEFAFEP_01575 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IAEFAFEP_01576 7.4e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IAEFAFEP_01577 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAEFAFEP_01579 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAEFAFEP_01580 8.7e-75 marR K Transcriptional regulator, MarR family
IAEFAFEP_01581 1.7e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAEFAFEP_01582 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAEFAFEP_01583 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IAEFAFEP_01584 2.7e-129 IQ reductase
IAEFAFEP_01585 1.3e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IAEFAFEP_01586 4.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IAEFAFEP_01587 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IAEFAFEP_01588 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IAEFAFEP_01589 4.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAEFAFEP_01590 3.3e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IAEFAFEP_01591 5.8e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IAEFAFEP_01592 9.7e-92 bioY S BioY family
IAEFAFEP_01593 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IAEFAFEP_01594 0.0 uup S ABC transporter, ATP-binding protein
IAEFAFEP_01595 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAEFAFEP_01596 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAEFAFEP_01597 1e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IAEFAFEP_01598 0.0 ydaO E amino acid
IAEFAFEP_01599 1.9e-37
IAEFAFEP_01600 9e-113 yvyE 3.4.13.9 S YigZ family
IAEFAFEP_01601 2.9e-251 comFA L Helicase C-terminal domain protein
IAEFAFEP_01602 2.1e-128 comFC S Competence protein
IAEFAFEP_01603 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAEFAFEP_01604 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IAEFAFEP_01605 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IAEFAFEP_01606 4.1e-53 KT PspC domain protein
IAEFAFEP_01607 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IAEFAFEP_01608 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAEFAFEP_01609 1.6e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAEFAFEP_01610 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IAEFAFEP_01611 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IAEFAFEP_01612 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IAEFAFEP_01613 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
IAEFAFEP_01614 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAEFAFEP_01615 1.5e-76 yphH S Cupin domain
IAEFAFEP_01616 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IAEFAFEP_01617 6e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IAEFAFEP_01618 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IAEFAFEP_01619 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAEFAFEP_01620 5.2e-241 yfnA E amino acid
IAEFAFEP_01621 1.6e-82 S NADPH-dependent FMN reductase
IAEFAFEP_01623 7.7e-157 L Thioesterase-like superfamily
IAEFAFEP_01624 1.1e-50 lacA S transferase hexapeptide repeat
IAEFAFEP_01625 4.7e-260 argH 4.3.2.1 E argininosuccinate lyase
IAEFAFEP_01626 1.3e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IAEFAFEP_01627 4.1e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAEFAFEP_01628 2.7e-64 L Transposase IS200 like
IAEFAFEP_01629 8.2e-173 L transposase, IS605 OrfB family
IAEFAFEP_01630 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAEFAFEP_01631 4.9e-102 K Transcriptional regulator
IAEFAFEP_01632 1.4e-22 XK27_06785 V ABC transporter
IAEFAFEP_01633 6.5e-168 M Membrane
IAEFAFEP_01634 2.8e-40 S FMN_bind
IAEFAFEP_01635 0.0 yhcA V ABC transporter, ATP-binding protein
IAEFAFEP_01636 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
IAEFAFEP_01637 2.5e-73 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAEFAFEP_01638 2.9e-48 ybjQ S Belongs to the UPF0145 family
IAEFAFEP_01639 8e-78 rocF 3.5.3.1, 3.5.3.11 E Arginase family
IAEFAFEP_01641 1.8e-173 1.3.1.9 S Nitronate monooxygenase
IAEFAFEP_01642 4.7e-54 K Helix-turn-helix domain
IAEFAFEP_01643 1.2e-105 S Domain of unknown function (DUF4767)
IAEFAFEP_01644 7.7e-73
IAEFAFEP_01645 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IAEFAFEP_01646 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
IAEFAFEP_01647 1.6e-170 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
IAEFAFEP_01648 1.1e-90 yxeQ S MmgE/PrpD family
IAEFAFEP_01650 4.2e-113 papP P ABC transporter, permease protein
IAEFAFEP_01651 4.5e-115 P ABC transporter permease
IAEFAFEP_01652 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAEFAFEP_01653 3.1e-153 cjaA ET ABC transporter substrate-binding protein
IAEFAFEP_01654 6.1e-137 IQ KR domain
IAEFAFEP_01656 7.3e-214 hom1 1.1.1.3 E Homoserine dehydrogenase
IAEFAFEP_01657 3.8e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IAEFAFEP_01658 2e-245 mmuP E amino acid
IAEFAFEP_01659 4.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IAEFAFEP_01660 1.4e-169 yniA G Phosphotransferase enzyme family
IAEFAFEP_01661 2.8e-174 lytH 3.5.1.28 M Ami_3
IAEFAFEP_01662 6.1e-196 6.3.1.20 H Lipoate-protein ligase
IAEFAFEP_01663 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
IAEFAFEP_01664 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IAEFAFEP_01665 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IAEFAFEP_01666 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IAEFAFEP_01667 4.6e-71 yqeY S YqeY-like protein
IAEFAFEP_01668 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
IAEFAFEP_01669 1.7e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAEFAFEP_01670 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IAEFAFEP_01671 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAEFAFEP_01672 1.1e-155 recO L Involved in DNA repair and RecF pathway recombination
IAEFAFEP_01673 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IAEFAFEP_01674 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IAEFAFEP_01675 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IAEFAFEP_01676 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IAEFAFEP_01682 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IAEFAFEP_01683 3.9e-268 lysP E amino acid
IAEFAFEP_01685 1.3e-156 I alpha/beta hydrolase fold
IAEFAFEP_01686 2e-115 lssY 3.6.1.27 I phosphatase
IAEFAFEP_01687 2.8e-82 S Threonine/Serine exporter, ThrE
IAEFAFEP_01688 6.3e-126 thrE S Putative threonine/serine exporter
IAEFAFEP_01689 3.3e-29 cspA K Cold shock protein
IAEFAFEP_01690 4.4e-123 sirR K iron dependent repressor
IAEFAFEP_01691 1.6e-163 czcD P cation diffusion facilitator family transporter
IAEFAFEP_01692 1e-114 S membrane
IAEFAFEP_01693 1.1e-108 S VIT family
IAEFAFEP_01694 2.9e-81 usp1 T Belongs to the universal stress protein A family
IAEFAFEP_01695 8.1e-33 elaA S GNAT family
IAEFAFEP_01696 1.4e-215 S CAAX protease self-immunity
IAEFAFEP_01697 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAEFAFEP_01698 4.4e-58
IAEFAFEP_01699 1.9e-74 merR K MerR HTH family regulatory protein
IAEFAFEP_01700 5.6e-267 lmrB EGP Major facilitator Superfamily
IAEFAFEP_01701 2.4e-114 S Domain of unknown function (DUF4811)
IAEFAFEP_01702 8.5e-150 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IAEFAFEP_01703 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IAEFAFEP_01705 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAEFAFEP_01706 7.9e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IAEFAFEP_01707 3.1e-189 I Alpha beta
IAEFAFEP_01708 1e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
IAEFAFEP_01709 9.5e-250 yjjP S Putative threonine/serine exporter
IAEFAFEP_01710 1.3e-162 mleR K LysR family transcriptional regulator
IAEFAFEP_01711 4e-127 narI 1.7.5.1 C Nitrate reductase
IAEFAFEP_01712 3.1e-102 narJ C Nitrate reductase delta subunit
IAEFAFEP_01713 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
IAEFAFEP_01714 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAEFAFEP_01715 2.2e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IAEFAFEP_01716 4.3e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IAEFAFEP_01717 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IAEFAFEP_01718 3.6e-84 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IAEFAFEP_01719 5.3e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IAEFAFEP_01720 4.2e-40
IAEFAFEP_01721 1.4e-77 nreA T GAF domain
IAEFAFEP_01722 3.9e-182 comP 2.7.13.3 F Sensor histidine kinase
IAEFAFEP_01723 4e-116 nreC K PFAM regulatory protein LuxR
IAEFAFEP_01724 1.2e-39
IAEFAFEP_01725 3e-184
IAEFAFEP_01726 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IAEFAFEP_01728 3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IAEFAFEP_01729 1e-162 hipB K Helix-turn-helix
IAEFAFEP_01730 1.5e-58 yitW S Iron-sulfur cluster assembly protein
IAEFAFEP_01731 1.1e-215 narK P Major Facilitator Superfamily
IAEFAFEP_01732 1e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAEFAFEP_01733 6.4e-35 moaD 2.8.1.12 H ThiS family
IAEFAFEP_01734 2.2e-72 moaE 2.8.1.12 H MoaE protein
IAEFAFEP_01735 3.2e-56 S Flavodoxin
IAEFAFEP_01736 1.5e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAEFAFEP_01737 3.8e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
IAEFAFEP_01738 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
IAEFAFEP_01739 8e-54 yitW S Iron-sulfur cluster assembly protein
IAEFAFEP_01740 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
IAEFAFEP_01741 4.3e-258 XK27_04775 S PAS domain
IAEFAFEP_01742 2.4e-142 EG EamA-like transporter family
IAEFAFEP_01746 2.5e-08
IAEFAFEP_01747 1.1e-100 S D5 N terminal like
IAEFAFEP_01748 7.9e-146 L DNA replication protein
IAEFAFEP_01751 4e-16 K Cro/C1-type HTH DNA-binding domain
IAEFAFEP_01752 2e-197 L Belongs to the 'phage' integrase family
IAEFAFEP_01753 2.2e-52 S Putative inner membrane protein (DUF1819)
IAEFAFEP_01754 1.4e-101 S Domain of unknown function (DUF1788)
IAEFAFEP_01755 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
IAEFAFEP_01756 0.0 2.1.1.72 V Eco57I restriction-modification methylase
IAEFAFEP_01757 3.6e-191 L Belongs to the 'phage' integrase family
IAEFAFEP_01758 2.7e-302 V Eco57I restriction-modification methylase
IAEFAFEP_01759 0.0 S PglZ domain
IAEFAFEP_01760 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
IAEFAFEP_01761 0.0 yfjM S Protein of unknown function DUF262
IAEFAFEP_01762 3.3e-15
IAEFAFEP_01763 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IAEFAFEP_01764 1.2e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IAEFAFEP_01765 2.7e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAEFAFEP_01766 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAEFAFEP_01767 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAEFAFEP_01768 1e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAEFAFEP_01769 2.2e-131 stp 3.1.3.16 T phosphatase
IAEFAFEP_01770 0.0 KLT serine threonine protein kinase
IAEFAFEP_01771 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IAEFAFEP_01772 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IAEFAFEP_01773 4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
IAEFAFEP_01774 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IAEFAFEP_01775 3.6e-58 asp S Asp23 family, cell envelope-related function
IAEFAFEP_01776 5e-304 yloV S DAK2 domain fusion protein YloV
IAEFAFEP_01777 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAEFAFEP_01778 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IAEFAFEP_01779 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAEFAFEP_01780 4e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IAEFAFEP_01781 0.0 smc D Required for chromosome condensation and partitioning
IAEFAFEP_01782 1.1e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IAEFAFEP_01783 1.1e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAEFAFEP_01784 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAEFAFEP_01787 5.3e-62
IAEFAFEP_01788 1.2e-263 npr 1.11.1.1 C NADH oxidase
IAEFAFEP_01789 8.6e-276 lacS G Transporter
IAEFAFEP_01790 0.0 rafA 3.2.1.22 G alpha-galactosidase
IAEFAFEP_01791 2.3e-179 galR K Transcriptional regulator
IAEFAFEP_01792 3.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IAEFAFEP_01793 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IAEFAFEP_01794 1.4e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IAEFAFEP_01795 4.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
IAEFAFEP_01796 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
IAEFAFEP_01797 2e-35
IAEFAFEP_01798 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IAEFAFEP_01799 2.2e-117 tcyB U Binding-protein-dependent transport system inner membrane component
IAEFAFEP_01800 3.7e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IAEFAFEP_01801 2e-52
IAEFAFEP_01802 4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_01803 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IAEFAFEP_01804 4.5e-146 pnuC H nicotinamide mononucleotide transporter
IAEFAFEP_01805 1.1e-92 ymdB S Macro domain protein
IAEFAFEP_01806 0.0 pepO 3.4.24.71 O Peptidase family M13
IAEFAFEP_01807 1.8e-229 pbuG S permease
IAEFAFEP_01808 2.1e-45
IAEFAFEP_01809 4.9e-213 S Putative metallopeptidase domain
IAEFAFEP_01810 8e-205 3.1.3.1 S associated with various cellular activities
IAEFAFEP_01811 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IAEFAFEP_01812 6.8e-65 yeaO S Protein of unknown function, DUF488
IAEFAFEP_01814 1.4e-124 yrkL S Flavodoxin-like fold
IAEFAFEP_01815 1.5e-55
IAEFAFEP_01816 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IAEFAFEP_01817 1.1e-37 K transcriptional regulator
IAEFAFEP_01818 2.1e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IAEFAFEP_01819 6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAEFAFEP_01820 8.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IAEFAFEP_01821 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAEFAFEP_01822 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IAEFAFEP_01823 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAEFAFEP_01824 1.8e-21 gntT EG gluconate transmembrane transporter activity
IAEFAFEP_01825 6.9e-47
IAEFAFEP_01826 1.9e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IAEFAFEP_01827 5.1e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IAEFAFEP_01828 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
IAEFAFEP_01829 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAEFAFEP_01830 5.8e-97 metI P ABC transporter permease
IAEFAFEP_01831 6.4e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IAEFAFEP_01832 8.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAEFAFEP_01833 1.6e-196 brnQ U Component of the transport system for branched-chain amino acids
IAEFAFEP_01834 2.4e-122 iolS C Aldo keto reductase
IAEFAFEP_01835 7.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAEFAFEP_01836 1.6e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAEFAFEP_01837 1.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
IAEFAFEP_01838 2.4e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IAEFAFEP_01840 1.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IAEFAFEP_01841 3.6e-134 pnuC H nicotinamide mononucleotide transporter
IAEFAFEP_01842 2.5e-297 ybeC E amino acid
IAEFAFEP_01843 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAEFAFEP_01844 1.6e-141 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
IAEFAFEP_01845 1.3e-101 G Glycosyl hydrolases family 8
IAEFAFEP_01846 9.3e-09 G Glycosyl hydrolases family 8
IAEFAFEP_01847 3.3e-186 ydaM M Glycosyl transferase family group 2
IAEFAFEP_01849 2.6e-78
IAEFAFEP_01850 5.3e-207 V domain protein
IAEFAFEP_01851 1.9e-92 K Transcriptional regulator (TetR family)
IAEFAFEP_01852 8.1e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IAEFAFEP_01853 6.3e-168
IAEFAFEP_01855 4e-83 zur P Belongs to the Fur family
IAEFAFEP_01856 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
IAEFAFEP_01857 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IAEFAFEP_01858 1.1e-205 yfnA E Amino Acid
IAEFAFEP_01859 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IAEFAFEP_01860 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IAEFAFEP_01861 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAEFAFEP_01862 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAEFAFEP_01863 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAEFAFEP_01864 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IAEFAFEP_01865 2.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IAEFAFEP_01866 3e-87 yabR J RNA binding
IAEFAFEP_01867 1.5e-56 divIC D Septum formation initiator
IAEFAFEP_01868 1.6e-39 yabO J S4 domain protein
IAEFAFEP_01869 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAEFAFEP_01870 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IAEFAFEP_01871 8.1e-114 S (CBS) domain
IAEFAFEP_01872 5e-57 L Toxic component of a toxin-antitoxin (TA) module
IAEFAFEP_01873 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAEFAFEP_01874 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IAEFAFEP_01875 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IAEFAFEP_01876 1.4e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IAEFAFEP_01877 4.9e-157 htpX O Belongs to the peptidase M48B family
IAEFAFEP_01878 8.7e-88 lemA S LemA family
IAEFAFEP_01879 9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAEFAFEP_01880 1.1e-96 L Probable transposase
IAEFAFEP_01881 3.3e-16 EGP Major Facilitator Superfamily
IAEFAFEP_01882 7.4e-76 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IAEFAFEP_01883 1e-72 O OsmC-like protein
IAEFAFEP_01884 4.7e-76 K Transcriptional regulator
IAEFAFEP_01885 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
IAEFAFEP_01886 6.7e-108 proWZ P ABC transporter permease
IAEFAFEP_01887 9.3e-141 proV E ABC transporter, ATP-binding protein
IAEFAFEP_01888 6.6e-100 proW P ABC transporter, permease protein
IAEFAFEP_01889 8.8e-181 C Zinc-binding dehydrogenase
IAEFAFEP_01890 6.3e-196 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
IAEFAFEP_01891 1.2e-224 4.4.1.8 E Aminotransferase, class I
IAEFAFEP_01892 1.2e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IAEFAFEP_01893 7.1e-203 xerS L Belongs to the 'phage' integrase family
IAEFAFEP_01894 1.2e-61 ywkB S Membrane transport protein
IAEFAFEP_01895 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
IAEFAFEP_01896 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IAEFAFEP_01897 3.4e-80 hmpT S ECF-type riboflavin transporter, S component
IAEFAFEP_01898 5.6e-166 1.1.1.346 C Aldo keto reductase
IAEFAFEP_01899 8.9e-162 S DUF218 domain
IAEFAFEP_01901 6.3e-96 K Acetyltransferase (GNAT) domain
IAEFAFEP_01902 1.3e-164 I alpha/beta hydrolase fold
IAEFAFEP_01903 4.7e-120 S Phage minor capsid protein 2
IAEFAFEP_01906 3.4e-216 2.6.1.1 E Aminotransferase
IAEFAFEP_01907 1.5e-104 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
IAEFAFEP_01908 8e-70 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
IAEFAFEP_01909 4.1e-63 EGP Sugar (and other) transporter
IAEFAFEP_01910 3.6e-53 EGP Sugar (and other) transporter
IAEFAFEP_01911 1.9e-93 EGP Sugar (and other) transporter
IAEFAFEP_01912 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IAEFAFEP_01913 1.3e-85 S Fic/DOC family
IAEFAFEP_01914 8.1e-77 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IAEFAFEP_01915 3.1e-105 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IAEFAFEP_01916 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IAEFAFEP_01917 1.7e-260 arcD E Amino acid permease
IAEFAFEP_01918 2.2e-118 5.1.1.13 M racemase activity, acting on amino acids and derivatives
IAEFAFEP_01919 9.5e-36 odh 1.5.1.28 C NAD NADP octopine nopaline dehydrogenase
IAEFAFEP_01920 3.5e-110 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
IAEFAFEP_01921 1.7e-29 clcA P chloride
IAEFAFEP_01922 2.3e-67 clcA P chloride
IAEFAFEP_01923 6.5e-18 lmrB EGP Major facilitator Superfamily
IAEFAFEP_01924 9.3e-245 yhjX P Major Facilitator Superfamily
IAEFAFEP_01925 4.4e-118 S Protein of unknown function (DUF554)
IAEFAFEP_01926 2.6e-255 rarA L recombination factor protein RarA
IAEFAFEP_01928 0.0 oppD EP Psort location Cytoplasmic, score
IAEFAFEP_01929 8e-243 codA 3.5.4.1 F cytosine deaminase
IAEFAFEP_01930 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
IAEFAFEP_01931 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
IAEFAFEP_01932 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IAEFAFEP_01933 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IAEFAFEP_01934 2.3e-71 yqkB S Belongs to the HesB IscA family
IAEFAFEP_01935 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
IAEFAFEP_01936 5.2e-95 S Protein of unknown function (DUF1440)
IAEFAFEP_01937 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAEFAFEP_01938 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IAEFAFEP_01939 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IAEFAFEP_01940 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
IAEFAFEP_01941 7.3e-155 D DNA integration
IAEFAFEP_01942 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAEFAFEP_01943 8.1e-165 dprA LU DNA protecting protein DprA
IAEFAFEP_01944 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAEFAFEP_01945 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAEFAFEP_01946 3.1e-36 yozE S Belongs to the UPF0346 family
IAEFAFEP_01947 2.7e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IAEFAFEP_01948 1.1e-167 ypmR E lipolytic protein G-D-S-L family
IAEFAFEP_01949 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
IAEFAFEP_01950 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
IAEFAFEP_01951 1.2e-152 DegV S EDD domain protein, DegV family
IAEFAFEP_01952 1.2e-109 hlyIII S protein, hemolysin III
IAEFAFEP_01953 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAEFAFEP_01954 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IAEFAFEP_01955 0.0 yfmR S ABC transporter, ATP-binding protein
IAEFAFEP_01956 7.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IAEFAFEP_01957 1.8e-164 xerD L Phage integrase, N-terminal SAM-like domain
IAEFAFEP_01958 1.8e-234 S Tetratricopeptide repeat protein
IAEFAFEP_01959 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IAEFAFEP_01960 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IAEFAFEP_01961 1.7e-208 rpsA 1.17.7.4 J Ribosomal protein S1
IAEFAFEP_01962 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IAEFAFEP_01963 9.7e-31 M Lysin motif
IAEFAFEP_01964 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IAEFAFEP_01965 3.9e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
IAEFAFEP_01966 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IAEFAFEP_01967 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IAEFAFEP_01968 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAEFAFEP_01969 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAEFAFEP_01970 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IAEFAFEP_01971 5.3e-132 xerD D recombinase XerD
IAEFAFEP_01972 1.6e-168 cvfB S S1 domain
IAEFAFEP_01973 7e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IAEFAFEP_01974 0.0 dnaE 2.7.7.7 L DNA polymerase
IAEFAFEP_01976 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IAEFAFEP_01977 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAEFAFEP_01978 4.5e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
IAEFAFEP_01979 2e-118 ktrA P domain protein
IAEFAFEP_01980 3e-227 ktrB P Potassium uptake protein
IAEFAFEP_01981 3.3e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAEFAFEP_01982 1.7e-218 patA 2.6.1.1 E Aminotransferase
IAEFAFEP_01983 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IAEFAFEP_01984 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAEFAFEP_01985 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IAEFAFEP_01986 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IAEFAFEP_01987 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IAEFAFEP_01988 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
IAEFAFEP_01989 6.7e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAEFAFEP_01990 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IAEFAFEP_01991 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IAEFAFEP_01992 3.9e-33 yneR S Belongs to the HesB IscA family
IAEFAFEP_01993 3.6e-140 S NADPH-dependent FMN reductase
IAEFAFEP_01994 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IAEFAFEP_01995 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IAEFAFEP_01996 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
IAEFAFEP_01997 4.9e-63 S Domain of unknown function (DUF4828)
IAEFAFEP_01998 1.1e-189 mocA S Oxidoreductase
IAEFAFEP_01999 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
IAEFAFEP_02001 3.6e-73 gtcA S Teichoic acid glycosylation protein
IAEFAFEP_02002 8.5e-78 fld C Flavodoxin
IAEFAFEP_02003 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
IAEFAFEP_02004 0.0 XK27_08315 M Sulfatase
IAEFAFEP_02005 2.7e-139 yihY S Belongs to the UPF0761 family
IAEFAFEP_02006 3.8e-31 S Protein of unknown function (DUF2922)
IAEFAFEP_02007 1.3e-07
IAEFAFEP_02008 4.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
IAEFAFEP_02009 1.1e-118 rfbP M Bacterial sugar transferase
IAEFAFEP_02010 4.6e-148 cps1D M Domain of unknown function (DUF4422)
IAEFAFEP_02011 1.2e-94 cps3F
IAEFAFEP_02012 4.5e-45 M biosynthesis protein
IAEFAFEP_02013 1.4e-52 cps3I G Acyltransferase family
IAEFAFEP_02014 5.8e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IAEFAFEP_02015 8.6e-235 mepA V MATE efflux family protein
IAEFAFEP_02016 9.7e-225 amtB P ammonium transporter
IAEFAFEP_02018 4.2e-133 XK27_08845 S ABC transporter, ATP-binding protein
IAEFAFEP_02019 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IAEFAFEP_02020 7e-181 ABC-SBP S ABC transporter
IAEFAFEP_02021 5.8e-291 S ABC transporter, ATP-binding protein
IAEFAFEP_02022 1.8e-206 nrnB S DHHA1 domain
IAEFAFEP_02024 5.1e-110 M ErfK YbiS YcfS YnhG
IAEFAFEP_02025 1.4e-83 nrdI F NrdI Flavodoxin like
IAEFAFEP_02026 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAEFAFEP_02027 9.7e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
IAEFAFEP_02028 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
IAEFAFEP_02029 5e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
IAEFAFEP_02030 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IAEFAFEP_02031 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
IAEFAFEP_02032 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IAEFAFEP_02033 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAEFAFEP_02034 1.1e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IAEFAFEP_02035 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAEFAFEP_02036 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAEFAFEP_02037 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAEFAFEP_02038 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAEFAFEP_02039 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IAEFAFEP_02040 5.9e-243 S response to antibiotic
IAEFAFEP_02041 2.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
IAEFAFEP_02042 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAEFAFEP_02043 7.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAEFAFEP_02044 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAEFAFEP_02045 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IAEFAFEP_02046 3.7e-164 K AI-2E family transporter
IAEFAFEP_02047 3.1e-10 K transcriptional regulator
IAEFAFEP_02048 1.9e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IAEFAFEP_02049 4.7e-14
IAEFAFEP_02050 4e-156 V ABC transporter, ATP-binding protein
IAEFAFEP_02051 7.8e-64 gntR1 K Transcriptional regulator, GntR family
IAEFAFEP_02052 1.4e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IAEFAFEP_02053 6.5e-89 S Bacterial membrane protein, YfhO
IAEFAFEP_02054 5.9e-212 S Psort location CytoplasmicMembrane, score
IAEFAFEP_02055 3.6e-148 ykoT GT2 M Glycosyl transferase family 2
IAEFAFEP_02056 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
IAEFAFEP_02057 1.3e-95 M transferase activity, transferring glycosyl groups
IAEFAFEP_02058 2.2e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAEFAFEP_02059 5.9e-164 ykoT GT2 M Glycosyl transferase family 2
IAEFAFEP_02060 1.4e-140 yueF S AI-2E family transporter
IAEFAFEP_02061 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IAEFAFEP_02062 8.1e-09
IAEFAFEP_02063 1.2e-59 M repeat protein
IAEFAFEP_02064 1.9e-56 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IAEFAFEP_02065 1.3e-100 P Cadmium resistance transporter
IAEFAFEP_02066 3.2e-116 S Protein of unknown function (DUF554)
IAEFAFEP_02067 7.1e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAEFAFEP_02068 3.5e-157 P Belongs to the nlpA lipoprotein family
IAEFAFEP_02069 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAEFAFEP_02070 2.5e-37 V CAAX protease self-immunity
IAEFAFEP_02071 1.7e-67 psiE S Phosphate-starvation-inducible E
IAEFAFEP_02072 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IAEFAFEP_02073 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IAEFAFEP_02074 6.1e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IAEFAFEP_02075 6.2e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAEFAFEP_02076 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAEFAFEP_02077 1.1e-90 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IAEFAFEP_02078 2.6e-101 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
IAEFAFEP_02079 0.0 L Type III restriction enzyme, res subunit
IAEFAFEP_02080 3.2e-254 S Protein of unknown function DUF262
IAEFAFEP_02082 1.1e-15 tnp L MULE transposase domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)