ORF_ID e_value Gene_name EC_number CAZy COGs Description
JPEALGIE_00001 1.3e-137 L Transposase
JPEALGIE_00002 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JPEALGIE_00003 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JPEALGIE_00004 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JPEALGIE_00005 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
JPEALGIE_00007 2.7e-61 divIC D Septum formation initiator
JPEALGIE_00008 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JPEALGIE_00009 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JPEALGIE_00010 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JPEALGIE_00011 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JPEALGIE_00012 1.1e-29 yyzM S Protein conserved in bacteria
JPEALGIE_00013 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JPEALGIE_00014 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JPEALGIE_00015 8.5e-134 parB K Belongs to the ParB family
JPEALGIE_00016 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JPEALGIE_00017 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JPEALGIE_00018 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
JPEALGIE_00022 0.0 XK27_10405 S Bacterial membrane protein YfhO
JPEALGIE_00023 6.7e-306 ybiT S abc transporter atp-binding protein
JPEALGIE_00024 4.2e-153 yvjA S membrane
JPEALGIE_00025 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JPEALGIE_00026 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JPEALGIE_00027 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JPEALGIE_00028 1.6e-45 yaaA S S4 domain protein YaaA
JPEALGIE_00029 1.7e-66 ymfF S Peptidase M16
JPEALGIE_00030 1.3e-156 ymfF S Peptidase M16
JPEALGIE_00031 1.2e-241 ymfH S Peptidase M16
JPEALGIE_00032 6.3e-138 ymfM S sequence-specific DNA binding
JPEALGIE_00033 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JPEALGIE_00034 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPEALGIE_00035 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPEALGIE_00036 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPEALGIE_00037 5.3e-85 lytE M LysM domain protein
JPEALGIE_00038 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
JPEALGIE_00039 0.0 S Bacterial membrane protein, YfhO
JPEALGIE_00040 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JPEALGIE_00041 1.5e-77 F NUDIX domain
JPEALGIE_00042 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JPEALGIE_00043 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JPEALGIE_00044 3.9e-70 rplI J binds to the 23S rRNA
JPEALGIE_00045 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JPEALGIE_00046 8.2e-48 veg S Biofilm formation stimulator VEG
JPEALGIE_00047 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JPEALGIE_00048 2.7e-08
JPEALGIE_00049 4.8e-55 ypaA M Membrane
JPEALGIE_00050 6.4e-96 XK27_06935 K transcriptional regulator
JPEALGIE_00051 3.9e-161 XK27_06930 V domain protein
JPEALGIE_00052 1.2e-87 S Putative adhesin
JPEALGIE_00053 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
JPEALGIE_00055 1.7e-23 K negative regulation of transcription, DNA-templated
JPEALGIE_00056 4e-19 K negative regulation of transcription, DNA-templated
JPEALGIE_00057 3.4e-13 nudL L hydrolase
JPEALGIE_00058 1.1e-11 K CsbD-like
JPEALGIE_00059 3.1e-85 M Protein conserved in bacteria
JPEALGIE_00060 1.8e-23 S Small integral membrane protein
JPEALGIE_00061 9.1e-101
JPEALGIE_00062 3.7e-27 S Membrane
JPEALGIE_00064 2.7e-95 S Hydrophobic domain protein
JPEALGIE_00065 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
JPEALGIE_00068 5.1e-184 sip L Belongs to the 'phage' integrase family
JPEALGIE_00069 5.9e-20 S MerR HTH family regulatory protein
JPEALGIE_00070 2.1e-82 S Plasmid replication protein
JPEALGIE_00071 2e-20
JPEALGIE_00072 1.5e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JPEALGIE_00073 1.7e-35
JPEALGIE_00074 3.2e-10 S Sigma-70, region 4
JPEALGIE_00075 0.0 V Type II restriction enzyme, methylase subunits
JPEALGIE_00076 2.4e-28
JPEALGIE_00077 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JPEALGIE_00078 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JPEALGIE_00079 1.4e-36 metE 2.1.1.14 E Methionine synthase
JPEALGIE_00080 5.2e-55 metE 2.1.1.14 E Methionine synthase
JPEALGIE_00081 1.4e-53 metE 2.1.1.14 E Methionine synthase
JPEALGIE_00082 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
JPEALGIE_00084 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JPEALGIE_00085 9.3e-167 XK27_01785 S cog cog1284
JPEALGIE_00086 1.8e-147 yaaA S Belongs to the UPF0246 family
JPEALGIE_00087 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JPEALGIE_00088 2.6e-91 XK27_10930 K acetyltransferase
JPEALGIE_00089 7.5e-14
JPEALGIE_00090 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JPEALGIE_00091 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00092 4.2e-44 yrzB S Belongs to the UPF0473 family
JPEALGIE_00093 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JPEALGIE_00094 2.8e-44 yrzL S Belongs to the UPF0297 family
JPEALGIE_00095 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JPEALGIE_00096 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
JPEALGIE_00098 1.7e-215 int L Belongs to the 'phage' integrase family
JPEALGIE_00099 1.9e-18 S Domain of unknown function (DUF3173)
JPEALGIE_00100 1e-155 L Replication initiation factor
JPEALGIE_00101 3.9e-287 V ABC transporter transmembrane region
JPEALGIE_00102 3e-104 C Radical SAM
JPEALGIE_00103 7.5e-109 C Radical SAM
JPEALGIE_00105 1.4e-59 Z012_04635 K sequence-specific DNA binding
JPEALGIE_00106 3.2e-56 Z012_04635 K sequence-specific DNA binding
JPEALGIE_00107 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPEALGIE_00108 9.7e-30 S Domain of unknown function (DUF4649)
JPEALGIE_00109 7.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JPEALGIE_00110 1.8e-50 adk 2.7.4.3 F topology modulation protein
JPEALGIE_00111 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JPEALGIE_00112 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JPEALGIE_00113 1.7e-35 XK27_09805 S MORN repeat protein
JPEALGIE_00114 0.0 XK27_09800 I Acyltransferase
JPEALGIE_00115 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JPEALGIE_00116 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
JPEALGIE_00117 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JPEALGIE_00118 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
JPEALGIE_00119 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JPEALGIE_00120 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JPEALGIE_00121 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JPEALGIE_00122 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JPEALGIE_00123 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JPEALGIE_00124 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JPEALGIE_00125 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
JPEALGIE_00126 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JPEALGIE_00127 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JPEALGIE_00128 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JPEALGIE_00129 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JPEALGIE_00130 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JPEALGIE_00131 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JPEALGIE_00132 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JPEALGIE_00133 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JPEALGIE_00134 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JPEALGIE_00135 2.5e-23 rpmD J ribosomal protein l30
JPEALGIE_00136 4.4e-58 rplO J binds to the 23S rRNA
JPEALGIE_00137 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JPEALGIE_00138 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JPEALGIE_00139 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JPEALGIE_00140 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JPEALGIE_00141 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JPEALGIE_00142 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JPEALGIE_00143 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPEALGIE_00144 3.3e-62 rplQ J ribosomal protein l17
JPEALGIE_00145 2e-94 L PFAM Integrase, catalytic core
JPEALGIE_00146 2e-35 L PFAM Integrase, catalytic core
JPEALGIE_00149 3.3e-95 ywlG S Belongs to the UPF0340 family
JPEALGIE_00150 1.2e-85 treR K trehalose operon
JPEALGIE_00151 5.8e-21 treR K DNA-binding transcription factor activity
JPEALGIE_00152 1.4e-54 treB 2.7.1.201 G PTS System
JPEALGIE_00153 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPEALGIE_00154 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPEALGIE_00155 0.0 pepO 3.4.24.71 O Peptidase family M13
JPEALGIE_00156 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
JPEALGIE_00157 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPEALGIE_00158 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPEALGIE_00159 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPEALGIE_00160 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPEALGIE_00161 1.2e-277 thrC 4.2.3.1 E Threonine synthase
JPEALGIE_00162 3.2e-226 norN V Mate efflux family protein
JPEALGIE_00163 1.8e-57 asp S cog cog1302
JPEALGIE_00164 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
JPEALGIE_00165 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JPEALGIE_00166 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
JPEALGIE_00167 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
JPEALGIE_00168 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JPEALGIE_00169 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JPEALGIE_00170 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPEALGIE_00171 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPEALGIE_00172 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPEALGIE_00173 2.9e-68 S cog cog4699
JPEALGIE_00174 6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JPEALGIE_00175 9.1e-156 cglB U protein transport across the cell outer membrane
JPEALGIE_00176 8.5e-43 comGC U Required for transformation and DNA binding
JPEALGIE_00177 1.8e-57 cglD NU Competence protein
JPEALGIE_00178 1.4e-15 NU Type II secretory pathway pseudopilin
JPEALGIE_00179 1.5e-71 comGF U Competence protein ComGF
JPEALGIE_00180 2e-12 comGF U Putative Competence protein ComGF
JPEALGIE_00181 1.1e-175 ytxK 2.1.1.72 L DNA methylase
JPEALGIE_00182 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JPEALGIE_00183 2.6e-26 lanR K sequence-specific DNA binding
JPEALGIE_00184 1.1e-66 V CAAX protease self-immunity
JPEALGIE_00186 8.7e-111 S CAAX amino terminal protease family protein
JPEALGIE_00187 6.7e-98 blpT
JPEALGIE_00188 2.9e-28 blpT
JPEALGIE_00189 3e-47 spiA K sequence-specific DNA binding
JPEALGIE_00192 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JPEALGIE_00193 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
JPEALGIE_00194 5e-44 V CAAX protease self-immunity
JPEALGIE_00195 4.6e-140 cppA E CppA N-terminal
JPEALGIE_00196 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
JPEALGIE_00197 4.4e-115 ybbL S abc transporter atp-binding protein
JPEALGIE_00198 1.5e-127 ybbM S transport system, permease component
JPEALGIE_00199 1.4e-33 D nuclear chromosome segregation
JPEALGIE_00200 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
JPEALGIE_00201 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPEALGIE_00202 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
JPEALGIE_00203 0.0 pflB 2.3.1.54 C formate acetyltransferase'
JPEALGIE_00204 1.3e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPEALGIE_00206 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JPEALGIE_00207 1.4e-159 yxeN P ABC transporter (Permease
JPEALGIE_00208 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_00209 6.1e-08 S Protein of unknown function (DUF4059)
JPEALGIE_00210 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JPEALGIE_00211 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
JPEALGIE_00212 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JPEALGIE_00213 8.4e-196 ylbL T Belongs to the peptidase S16 family
JPEALGIE_00214 1.3e-184 yhcC S radical SAM protein
JPEALGIE_00215 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
JPEALGIE_00217 0.0 yjcE P NhaP-type Na H and K H antiporters
JPEALGIE_00218 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
JPEALGIE_00219 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
JPEALGIE_00220 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JPEALGIE_00223 2.4e-75 XK27_03180 T universal stress protein
JPEALGIE_00224 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
JPEALGIE_00225 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JPEALGIE_00226 3.4e-100 pncA Q isochorismatase
JPEALGIE_00227 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
JPEALGIE_00228 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JPEALGIE_00229 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPEALGIE_00230 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPEALGIE_00231 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
JPEALGIE_00232 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPEALGIE_00233 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JPEALGIE_00234 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPEALGIE_00235 4e-59
JPEALGIE_00236 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPEALGIE_00237 1.8e-98 yqeG S hydrolase of the HAD superfamily
JPEALGIE_00238 2.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JPEALGIE_00239 3.5e-49 yhbY J RNA-binding protein
JPEALGIE_00240 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JPEALGIE_00241 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JPEALGIE_00242 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JPEALGIE_00243 2e-140 yqeM Q Methyltransferase domain protein
JPEALGIE_00244 1.2e-202 ylbM S Belongs to the UPF0348 family
JPEALGIE_00245 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
JPEALGIE_00246 6.5e-55
JPEALGIE_00247 4.8e-11
JPEALGIE_00248 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JPEALGIE_00249 2.3e-133 ecsA V abc transporter atp-binding protein
JPEALGIE_00250 1.6e-183 ecsB U ABC transporter
JPEALGIE_00251 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
JPEALGIE_00252 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JPEALGIE_00254 7.7e-227 ytfP S Flavoprotein
JPEALGIE_00255 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JPEALGIE_00256 7.4e-64 XK27_02560 S cog cog2151
JPEALGIE_00257 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
JPEALGIE_00258 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
JPEALGIE_00259 5.3e-119 K transcriptional regulator, MerR family
JPEALGIE_00260 5.1e-47 L transposase activity
JPEALGIE_00261 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JPEALGIE_00262 6.1e-27
JPEALGIE_00263 0.0 ctpE P E1-E2 ATPase
JPEALGIE_00264 1.6e-55
JPEALGIE_00265 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JPEALGIE_00266 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
JPEALGIE_00267 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JPEALGIE_00268 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JPEALGIE_00269 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
JPEALGIE_00270 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JPEALGIE_00271 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JPEALGIE_00272 2.7e-73 copY K Copper transport repressor, CopY TcrY family
JPEALGIE_00273 0.0 copA 3.6.3.54 P P-type ATPase
JPEALGIE_00274 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
JPEALGIE_00275 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JPEALGIE_00276 6e-115 papP P ABC transporter (Permease
JPEALGIE_00277 3e-106 P ABC transporter (Permease
JPEALGIE_00278 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_00279 1.1e-155 cjaA ET ABC transporter substrate-binding protein
JPEALGIE_00283 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JPEALGIE_00284 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
JPEALGIE_00285 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JPEALGIE_00286 1.6e-200 yjbB G Permeases of the major facilitator superfamily
JPEALGIE_00287 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPEALGIE_00288 7.8e-100 thiT S Thiamine transporter
JPEALGIE_00289 1.9e-62 yjqA S Bacterial PH domain
JPEALGIE_00290 2.3e-154 corA P CorA-like protein
JPEALGIE_00291 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JPEALGIE_00293 1e-41 yazA L endonuclease containing a URI domain
JPEALGIE_00294 2.3e-139 yabB 2.1.1.223 L Methyltransferase
JPEALGIE_00295 4.1e-22 nodB3 G polysaccharide deacetylase
JPEALGIE_00296 1.7e-77 nodB3 G polysaccharide deacetylase
JPEALGIE_00297 8.3e-142 plsC 2.3.1.51 I Acyltransferase
JPEALGIE_00298 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JPEALGIE_00299 0.0 comEC S Competence protein ComEC
JPEALGIE_00300 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPEALGIE_00301 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
JPEALGIE_00302 3.3e-231 ytoI K transcriptional regulator containing CBS domains
JPEALGIE_00303 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JPEALGIE_00304 7.4e-164 rbn E Belongs to the UPF0761 family
JPEALGIE_00305 3.7e-85 ccl S cog cog4708
JPEALGIE_00306 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JPEALGIE_00307 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JPEALGIE_00308 1.9e-55 L Transposase
JPEALGIE_00309 2.1e-74 S QueT transporter
JPEALGIE_00310 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
JPEALGIE_00311 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
JPEALGIE_00312 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JPEALGIE_00313 4.1e-37 ylqC L Belongs to the UPF0109 family
JPEALGIE_00314 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JPEALGIE_00315 0.0 ydaO E amino acid
JPEALGIE_00316 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
JPEALGIE_00317 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JPEALGIE_00318 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
JPEALGIE_00319 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JPEALGIE_00320 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JPEALGIE_00321 7.8e-171 murB 1.3.1.98 M cell wall formation
JPEALGIE_00322 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JPEALGIE_00323 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
JPEALGIE_00324 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
JPEALGIE_00325 2.3e-206 potD P spermidine putrescine ABC transporter
JPEALGIE_00326 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
JPEALGIE_00327 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
JPEALGIE_00328 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
JPEALGIE_00329 2.6e-95 GK ROK family
JPEALGIE_00330 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JPEALGIE_00331 3.9e-104 wecD M Acetyltransferase GNAT family
JPEALGIE_00332 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JPEALGIE_00333 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
JPEALGIE_00334 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
JPEALGIE_00336 2.2e-58 lrgA S Effector of murein hydrolase LrgA
JPEALGIE_00337 2.2e-117 lrgB M effector of murein hydrolase
JPEALGIE_00338 2.6e-109 3.1.3.18 S IA, variant 1
JPEALGIE_00339 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPEALGIE_00340 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JPEALGIE_00341 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
JPEALGIE_00342 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JPEALGIE_00343 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_00344 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_00345 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
JPEALGIE_00347 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
JPEALGIE_00349 6.6e-30 ycaO O OsmC-like protein
JPEALGIE_00350 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
JPEALGIE_00353 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPEALGIE_00355 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JPEALGIE_00356 2.4e-16 XK27_00735
JPEALGIE_00357 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_00358 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
JPEALGIE_00359 2.6e-32 S CAAX amino terminal protease family protein
JPEALGIE_00360 1.2e-55 V CAAX protease self-immunity
JPEALGIE_00362 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JPEALGIE_00363 2.9e-84 mutT 3.6.1.55 F Nudix family
JPEALGIE_00364 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
JPEALGIE_00365 7.2e-136 ET ABC transporter
JPEALGIE_00366 3.4e-200 arcT 2.6.1.1 E Aminotransferase
JPEALGIE_00367 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
JPEALGIE_00368 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JPEALGIE_00369 1.1e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JPEALGIE_00370 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JPEALGIE_00371 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JPEALGIE_00372 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
JPEALGIE_00373 5.4e-251 M Psort location CytoplasmicMembrane, score
JPEALGIE_00374 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JPEALGIE_00375 1.2e-231
JPEALGIE_00376 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JPEALGIE_00377 7.6e-126 ycbB S Glycosyl transferase family 2
JPEALGIE_00378 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
JPEALGIE_00379 2.6e-220 amrA S polysaccharide biosynthetic process
JPEALGIE_00380 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
JPEALGIE_00381 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
JPEALGIE_00382 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
JPEALGIE_00383 1.1e-142 rgpC GM Transport permease protein
JPEALGIE_00384 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JPEALGIE_00385 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPEALGIE_00386 0.0 rgpF M Rhamnan synthesis protein F
JPEALGIE_00387 6.2e-120 radC E Belongs to the UPF0758 family
JPEALGIE_00388 1.6e-131 puuD T peptidase C26
JPEALGIE_00389 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JPEALGIE_00390 9e-59 XK27_04120 S Putative amino acid metabolism
JPEALGIE_00391 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
JPEALGIE_00392 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JPEALGIE_00393 5.8e-103 yjbK S Adenylate cyclase
JPEALGIE_00394 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
JPEALGIE_00395 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JPEALGIE_00396 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JPEALGIE_00397 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JPEALGIE_00398 3.7e-38 L transposase activity
JPEALGIE_00399 1.4e-38 L transposase activity
JPEALGIE_00400 9.3e-29 L transposition
JPEALGIE_00401 4e-110 L PFAM Integrase catalytic region
JPEALGIE_00402 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
JPEALGIE_00403 2e-21 tatD L hydrolase, TatD family'
JPEALGIE_00404 5.5e-23 oppF P Belongs to the ABC transporter superfamily
JPEALGIE_00405 1.2e-24 oppF P Belongs to the ABC transporter superfamily
JPEALGIE_00406 4.1e-158 L COG2801 Transposase and inactivated derivatives
JPEALGIE_00407 8.1e-45 L Transposase
JPEALGIE_00408 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JPEALGIE_00409 1.1e-270 amiC P ABC transporter (Permease
JPEALGIE_00410 2.4e-167 amiD P ABC transporter (Permease
JPEALGIE_00411 2.2e-204 oppD P Belongs to the ABC transporter superfamily
JPEALGIE_00412 4.3e-172 oppF P Belongs to the ABC transporter superfamily
JPEALGIE_00413 9e-131 V ATPase activity
JPEALGIE_00414 9.8e-121 skfE V abc transporter atp-binding protein
JPEALGIE_00415 8.6e-63 yvoA_1 K Transcriptional
JPEALGIE_00416 5.3e-147 supH S overlaps another CDS with the same product name
JPEALGIE_00417 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
JPEALGIE_00418 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JPEALGIE_00419 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JPEALGIE_00420 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
JPEALGIE_00421 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JPEALGIE_00422 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JPEALGIE_00423 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JPEALGIE_00424 9e-133 stp 3.1.3.16 T phosphatase
JPEALGIE_00425 1.7e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
JPEALGIE_00426 9.1e-119 yvqF KT membrane
JPEALGIE_00427 1.9e-173 vraS 2.7.13.3 T Histidine kinase
JPEALGIE_00428 8.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPEALGIE_00431 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JPEALGIE_00432 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JPEALGIE_00433 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JPEALGIE_00434 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JPEALGIE_00435 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00436 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00437 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00438 6.4e-62 L Transposase
JPEALGIE_00439 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
JPEALGIE_00440 4.3e-40 V abc transporter atp-binding protein
JPEALGIE_00441 2.5e-101 V abc transporter atp-binding protein
JPEALGIE_00442 5.1e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
JPEALGIE_00443 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
JPEALGIE_00444 1.2e-25 L transposition
JPEALGIE_00445 2.7e-08 L Integrase core domain protein
JPEALGIE_00446 2.3e-184 galR K Transcriptional regulator
JPEALGIE_00447 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JPEALGIE_00448 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JPEALGIE_00449 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPEALGIE_00450 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JPEALGIE_00451 0.0 lacS G transporter
JPEALGIE_00452 0.0 lacL 3.2.1.23 G -beta-galactosidase
JPEALGIE_00453 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JPEALGIE_00454 0.0 sbcC L ATPase involved in DNA repair
JPEALGIE_00455 1.4e-84
JPEALGIE_00457 1.8e-87 L transposase activity
JPEALGIE_00458 1.4e-150 L Integrase core domain protein
JPEALGIE_00459 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPEALGIE_00461 5.5e-258 I radical SAM domain protein
JPEALGIE_00462 1.2e-176 EGP Major Facilitator Superfamily
JPEALGIE_00463 3.9e-110 C Fe-S oxidoreductases
JPEALGIE_00465 1.1e-151 V MatE
JPEALGIE_00466 1.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
JPEALGIE_00467 5e-161 hrtB V MacB-like periplasmic core domain
JPEALGIE_00469 0.0 M family 8
JPEALGIE_00470 2.7e-09
JPEALGIE_00471 5.6e-08
JPEALGIE_00472 5.8e-109 MA20_06410 E LysE type translocator
JPEALGIE_00473 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
JPEALGIE_00474 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
JPEALGIE_00475 1e-137
JPEALGIE_00476 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPEALGIE_00477 4.5e-61
JPEALGIE_00479 9.3e-72 S Signal peptide protein, YSIRK family
JPEALGIE_00480 1.4e-54 K response regulator
JPEALGIE_00481 1.1e-37 BP1961 P nitric oxide dioxygenase activity
JPEALGIE_00483 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
JPEALGIE_00484 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPEALGIE_00485 6.8e-161 yvgN C reductase
JPEALGIE_00486 3e-102 yoaK S Protein of unknown function (DUF1275)
JPEALGIE_00487 1.4e-110 drgA C Nitroreductase
JPEALGIE_00488 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPEALGIE_00489 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
JPEALGIE_00490 5.6e-77 ywnA K Transcriptional regulator
JPEALGIE_00491 9.5e-150 1.13.11.2 S glyoxalase
JPEALGIE_00492 5.1e-110 XK27_02070 S nitroreductase
JPEALGIE_00493 4e-227 yfnA E amino acid
JPEALGIE_00495 4.8e-25 csbD K CsbD-like
JPEALGIE_00496 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPEALGIE_00497 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPEALGIE_00498 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
JPEALGIE_00499 2.2e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JPEALGIE_00500 4.5e-247 norM V Multidrug efflux pump
JPEALGIE_00501 2.1e-192 pbuX F xanthine permease
JPEALGIE_00503 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JPEALGIE_00504 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPEALGIE_00505 6.2e-166 T Histidine kinase
JPEALGIE_00506 1.9e-133 macB2 V ABC transporter, ATP-binding protein
JPEALGIE_00507 0.0 V ABC transporter (permease)
JPEALGIE_00508 6.1e-93 XK27_05000 S metal cluster binding
JPEALGIE_00509 2.6e-30 liaI KT membrane
JPEALGIE_00510 1.4e-15 liaI KT membrane
JPEALGIE_00511 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
JPEALGIE_00512 3.7e-122 S An automated process has identified a potential problem with this gene model
JPEALGIE_00514 2.3e-47 L Transposase
JPEALGIE_00515 4.6e-42 3.6.1.55 F NUDIX domain
JPEALGIE_00516 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
JPEALGIE_00517 1.6e-140 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
JPEALGIE_00518 7.2e-286 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
JPEALGIE_00519 6.6e-213 EGP Major facilitator Superfamily
JPEALGIE_00523 8.7e-159 XK27_09825 V abc transporter atp-binding protein
JPEALGIE_00524 1.4e-133 yvfS V ABC-2 type transporter
JPEALGIE_00525 1.5e-192 desK 2.7.13.3 T Histidine kinase
JPEALGIE_00526 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPEALGIE_00527 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
JPEALGIE_00528 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JPEALGIE_00529 1.2e-48 S Protein of unknown function (DUF917)
JPEALGIE_00530 1.4e-133 S Protein of unknown function (DUF917)
JPEALGIE_00531 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
JPEALGIE_00532 3e-111 proWZ P ABC transporter (Permease
JPEALGIE_00533 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
JPEALGIE_00534 1.5e-138 proV E abc transporter atp-binding protein
JPEALGIE_00535 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
JPEALGIE_00536 1.2e-62 bioY S biotin transmembrane transporter activity
JPEALGIE_00537 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JPEALGIE_00538 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JPEALGIE_00539 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JPEALGIE_00540 6.3e-23
JPEALGIE_00541 3e-13
JPEALGIE_00542 2.4e-92 pat 2.3.1.183 M acetyltransferase
JPEALGIE_00543 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JPEALGIE_00544 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JPEALGIE_00545 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JPEALGIE_00546 0.0 smc D Required for chromosome condensation and partitioning
JPEALGIE_00547 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JPEALGIE_00548 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPEALGIE_00549 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPEALGIE_00552 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
JPEALGIE_00553 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JPEALGIE_00555 2e-86 S ECF-type riboflavin transporter, S component
JPEALGIE_00556 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JPEALGIE_00557 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JPEALGIE_00558 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
JPEALGIE_00559 1.9e-294 yfmM S abc transporter atp-binding protein
JPEALGIE_00560 3.4e-258 noxE P NADH oxidase
JPEALGIE_00561 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JPEALGIE_00562 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPEALGIE_00563 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
JPEALGIE_00564 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
JPEALGIE_00565 5.3e-165 ypuA S secreted protein
JPEALGIE_00566 8.8e-60 L Transposase (IS116 IS110 IS902 family)
JPEALGIE_00567 4.2e-71 L Transposase (IS116 IS110 IS902 family)
JPEALGIE_00569 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPEALGIE_00570 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPEALGIE_00571 2.2e-34 nrdH O Glutaredoxin
JPEALGIE_00572 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JPEALGIE_00573 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
JPEALGIE_00574 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
JPEALGIE_00575 7.9e-39 ptsH G phosphocarrier protein Hpr
JPEALGIE_00576 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JPEALGIE_00577 4.1e-181 L Transposase
JPEALGIE_00578 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
JPEALGIE_00579 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JPEALGIE_00580 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
JPEALGIE_00581 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JPEALGIE_00582 0.0 uup S abc transporter atp-binding protein
JPEALGIE_00584 6.3e-13 MA20_06245 S yiaA/B two helix domain
JPEALGIE_00585 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
JPEALGIE_00586 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JPEALGIE_00587 8.7e-150 cobQ S glutamine amidotransferase
JPEALGIE_00588 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
JPEALGIE_00589 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JPEALGIE_00590 2.3e-168 ybbR S Protein conserved in bacteria
JPEALGIE_00591 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JPEALGIE_00592 1.3e-70 gtrA S GtrA-like protein
JPEALGIE_00593 7.9e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
JPEALGIE_00594 8.1e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JPEALGIE_00595 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
JPEALGIE_00596 2.1e-207 yurR 1.4.5.1 E oxidoreductase
JPEALGIE_00597 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JPEALGIE_00598 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JPEALGIE_00599 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JPEALGIE_00602 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
JPEALGIE_00603 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
JPEALGIE_00604 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JPEALGIE_00605 1.1e-121 ylfI S tigr01906
JPEALGIE_00606 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
JPEALGIE_00607 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JPEALGIE_00608 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JPEALGIE_00609 1.3e-22 XK27_08085
JPEALGIE_00610 5.2e-36 L transposase activity
JPEALGIE_00611 8.2e-22 L Transposase
JPEALGIE_00612 1.6e-55 L transposition
JPEALGIE_00613 8.2e-26 L Integrase core domain protein
JPEALGIE_00614 3.2e-89 L Transposase
JPEALGIE_00616 1.5e-29 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JPEALGIE_00617 1.6e-154 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JPEALGIE_00618 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JPEALGIE_00619 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JPEALGIE_00620 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JPEALGIE_00621 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JPEALGIE_00622 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JPEALGIE_00623 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JPEALGIE_00624 8.3e-21 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JPEALGIE_00625 1e-108 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JPEALGIE_00626 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JPEALGIE_00627 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
JPEALGIE_00628 5.6e-240 rodA D Belongs to the SEDS family
JPEALGIE_00629 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JPEALGIE_00630 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JPEALGIE_00631 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JPEALGIE_00632 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPEALGIE_00633 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
JPEALGIE_00634 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JPEALGIE_00635 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JPEALGIE_00636 2.9e-125 dnaD
JPEALGIE_00637 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JPEALGIE_00640 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JPEALGIE_00641 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
JPEALGIE_00642 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JPEALGIE_00643 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JPEALGIE_00644 3.7e-73 argR K Regulates arginine biosynthesis genes
JPEALGIE_00645 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
JPEALGIE_00646 1e-148 DegV S DegV family
JPEALGIE_00647 3.9e-143 ypmR E lipolytic protein G-D-S-L family
JPEALGIE_00648 1.7e-83 ypmS S Protein conserved in bacteria
JPEALGIE_00649 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JPEALGIE_00651 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
JPEALGIE_00652 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JPEALGIE_00653 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JPEALGIE_00654 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JPEALGIE_00655 2.5e-43 ysdA L Membrane
JPEALGIE_00656 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPEALGIE_00657 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPEALGIE_00658 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
JPEALGIE_00659 0.0 dnaE 2.7.7.7 L DNA polymerase
JPEALGIE_00660 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JPEALGIE_00661 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JPEALGIE_00664 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00665 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00666 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
JPEALGIE_00667 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
JPEALGIE_00668 4.4e-135 XK27_08845 S abc transporter atp-binding protein
JPEALGIE_00669 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPEALGIE_00670 1.6e-151 estA CE1 S Putative esterase
JPEALGIE_00671 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
JPEALGIE_00672 3.3e-14 XK27_08880
JPEALGIE_00673 2.3e-75 fld C Flavodoxin
JPEALGIE_00674 1.3e-282 clcA P Chloride transporter, ClC family
JPEALGIE_00675 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
JPEALGIE_00676 3.5e-206 XK27_05110 P Chloride transporter ClC family
JPEALGIE_00677 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JPEALGIE_00679 5.8e-80
JPEALGIE_00680 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
JPEALGIE_00681 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JPEALGIE_00682 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JPEALGIE_00683 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPEALGIE_00684 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JPEALGIE_00685 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JPEALGIE_00686 5.9e-26 G Domain of unknown function (DUF4832)
JPEALGIE_00687 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPEALGIE_00689 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPEALGIE_00690 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
JPEALGIE_00691 2.4e-124 endA F DNA RNA non-specific endonuclease
JPEALGIE_00692 4.2e-110 tcyB_2 P ABC transporter (permease)
JPEALGIE_00693 8e-115 gltJ P ABC transporter (Permease
JPEALGIE_00694 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JPEALGIE_00695 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_00696 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPEALGIE_00697 1.5e-247 vicK 2.7.13.3 T Histidine kinase
JPEALGIE_00698 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
JPEALGIE_00699 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JPEALGIE_00700 4.6e-146 yidA S hydrolases of the HAD superfamily
JPEALGIE_00701 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
JPEALGIE_00702 2.6e-67 ywiB S Domain of unknown function (DUF1934)
JPEALGIE_00703 0.0 pacL 3.6.3.8 P cation transport ATPase
JPEALGIE_00704 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JPEALGIE_00705 9.2e-183 yjjH S Calcineurin-like phosphoesterase
JPEALGIE_00706 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JPEALGIE_00707 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JPEALGIE_00708 2.5e-124 ftsE D cell division ATP-binding protein FtsE
JPEALGIE_00709 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JPEALGIE_00710 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
JPEALGIE_00711 1.3e-178 yubA S permease
JPEALGIE_00712 4.9e-224 G COG0457 FOG TPR repeat
JPEALGIE_00713 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JPEALGIE_00714 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JPEALGIE_00715 2.9e-90 ebsA S Family of unknown function (DUF5322)
JPEALGIE_00716 3.9e-15 M LysM domain
JPEALGIE_00717 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JPEALGIE_00718 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JPEALGIE_00719 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JPEALGIE_00720 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JPEALGIE_00721 1.6e-24 L Transposase
JPEALGIE_00722 1.7e-47 XK27_03610 K Gnat family
JPEALGIE_00723 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JPEALGIE_00724 2.4e-275 pepV 3.5.1.18 E Dipeptidase
JPEALGIE_00725 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
JPEALGIE_00727 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JPEALGIE_00728 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JPEALGIE_00729 9.6e-47 S Protein of unknown function (DUF1697)
JPEALGIE_00730 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JPEALGIE_00731 6.1e-36 clcA_2 P chloride channel
JPEALGIE_00732 2.2e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
JPEALGIE_00733 4.1e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
JPEALGIE_00734 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
JPEALGIE_00735 4.2e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
JPEALGIE_00736 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JPEALGIE_00737 1.1e-103 cps4C M biosynthesis protein
JPEALGIE_00738 1.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
JPEALGIE_00739 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JPEALGIE_00740 9.7e-23 rgpAc GT4 M group 1 family protein
JPEALGIE_00741 2.2e-22 L Transposase
JPEALGIE_00742 8.8e-139 L Integrase core domain
JPEALGIE_00743 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
JPEALGIE_00744 5.1e-204 L Transposase
JPEALGIE_00745 4.9e-90 L Transposase
JPEALGIE_00746 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JPEALGIE_00748 1.3e-23 L Transposase
JPEALGIE_00749 1.1e-235 cps1C S Polysaccharide biosynthesis protein
JPEALGIE_00750 2e-58 L COG2801 Transposase and inactivated derivatives
JPEALGIE_00751 3.3e-37 L transposase activity
JPEALGIE_00752 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
JPEALGIE_00753 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
JPEALGIE_00754 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
JPEALGIE_00755 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
JPEALGIE_00756 7.8e-16
JPEALGIE_00757 6.4e-33 cpsJ S Glycosyltransferase like family 2
JPEALGIE_00758 6.2e-112 L the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00759 3.1e-37 L Transposase
JPEALGIE_00760 2.2e-94 V VanZ like family
JPEALGIE_00761 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JPEALGIE_00762 5.6e-65 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
JPEALGIE_00763 1.1e-95 pgm G Belongs to the phosphoglycerate mutase family
JPEALGIE_00764 7.2e-104 G Belongs to the phosphoglycerate mutase family
JPEALGIE_00765 2.5e-99 G Belongs to the phosphoglycerate mutase family
JPEALGIE_00766 1.1e-198 S hmm pf01594
JPEALGIE_00767 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPEALGIE_00768 2.6e-97 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPEALGIE_00769 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPEALGIE_00770 4.9e-39 S granule-associated protein
JPEALGIE_00771 8.5e-290 S unusual protein kinase
JPEALGIE_00772 5.5e-34 estA E Lysophospholipase L1 and related esterases
JPEALGIE_00773 1.9e-59 estA E GDSL-like protein
JPEALGIE_00774 1.1e-158 rssA S Phospholipase, patatin family
JPEALGIE_00775 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_00776 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_00777 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_00778 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_00779 5.4e-19 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_00780 4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JPEALGIE_00781 7.2e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JPEALGIE_00782 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JPEALGIE_00783 5.7e-66 S the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00784 5e-38 P membrane protein (DUF2207)
JPEALGIE_00785 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JPEALGIE_00786 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JPEALGIE_00787 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPEALGIE_00788 0.0 lpdA 1.8.1.4 C Dehydrogenase
JPEALGIE_00789 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPEALGIE_00790 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPEALGIE_00791 8.5e-266 3.5.1.28 NU amidase activity
JPEALGIE_00792 1.9e-37 3.5.1.28 NU amidase activity
JPEALGIE_00793 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00794 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00795 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00796 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPEALGIE_00797 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPEALGIE_00798 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JPEALGIE_00799 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
JPEALGIE_00800 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
JPEALGIE_00801 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
JPEALGIE_00802 1.5e-233 ycdB P peroxidase
JPEALGIE_00803 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
JPEALGIE_00804 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JPEALGIE_00805 4.6e-25 tatA U protein secretion
JPEALGIE_00806 2.3e-23 L Transposase
JPEALGIE_00807 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
JPEALGIE_00808 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JPEALGIE_00809 3.7e-09
JPEALGIE_00811 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
JPEALGIE_00812 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JPEALGIE_00813 0.0 pepN 3.4.11.2 E aminopeptidase
JPEALGIE_00814 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
JPEALGIE_00815 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPEALGIE_00816 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPEALGIE_00817 5.9e-155 pstA P phosphate transport system permease
JPEALGIE_00818 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
JPEALGIE_00819 4.3e-158 pstS P phosphate
JPEALGIE_00820 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JPEALGIE_00821 1.1e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JPEALGIE_00822 1.9e-43 yktA S Belongs to the UPF0223 family
JPEALGIE_00823 4.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JPEALGIE_00824 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JPEALGIE_00825 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JPEALGIE_00826 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
JPEALGIE_00827 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
JPEALGIE_00828 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
JPEALGIE_00829 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JPEALGIE_00830 9.3e-62 S haloacid dehalogenase-like hydrolase
JPEALGIE_00831 1.8e-59 Q phosphatase activity
JPEALGIE_00832 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
JPEALGIE_00833 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JPEALGIE_00834 1.8e-240 agcS E (Alanine) symporter
JPEALGIE_00835 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JPEALGIE_00836 1.4e-104 yfiF3 K sequence-specific DNA binding
JPEALGIE_00837 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
JPEALGIE_00838 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
JPEALGIE_00840 1.8e-67 yecS P ABC transporter (Permease
JPEALGIE_00841 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
JPEALGIE_00842 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
JPEALGIE_00843 7.9e-266 dtpT E transporter
JPEALGIE_00845 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
JPEALGIE_00846 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JPEALGIE_00847 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JPEALGIE_00848 3.4e-61 csm6 S Psort location Cytoplasmic, score
JPEALGIE_00849 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
JPEALGIE_00850 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
JPEALGIE_00851 1.1e-116 csm3 L RAMP superfamily
JPEALGIE_00852 5.6e-62 csm2 L Pfam:DUF310
JPEALGIE_00853 0.0 csm1 S CRISPR-associated protein Csm1 family
JPEALGIE_00854 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
JPEALGIE_00855 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_00856 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_00857 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JPEALGIE_00858 6.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JPEALGIE_00859 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
JPEALGIE_00860 2.1e-98 S TraX protein
JPEALGIE_00862 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JPEALGIE_00863 6.5e-266 S Psort location CytoplasmicMembrane, score
JPEALGIE_00864 5.1e-26 dinF V drug transmembrane transporter activity
JPEALGIE_00865 9.6e-72 dinF V Mate efflux family protein
JPEALGIE_00866 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
JPEALGIE_00867 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
JPEALGIE_00868 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
JPEALGIE_00869 2.6e-143 2.4.2.3 F Phosphorylase superfamily
JPEALGIE_00872 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
JPEALGIE_00873 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
JPEALGIE_00874 6e-08 S Hydrolases of the alpha beta superfamily
JPEALGIE_00875 2.7e-106 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
JPEALGIE_00876 8.1e-52 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
JPEALGIE_00877 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JPEALGIE_00878 1.2e-158 czcD P cation diffusion facilitator family transporter
JPEALGIE_00879 1.2e-97 K Transcriptional regulator, TetR family
JPEALGIE_00881 6.1e-13 L Transposase
JPEALGIE_00882 1e-193 L Transposase
JPEALGIE_00883 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JPEALGIE_00884 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JPEALGIE_00885 6.6e-61 EGP Major facilitator Superfamily
JPEALGIE_00886 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
JPEALGIE_00887 1.3e-212 pqqE C radical SAM domain protein
JPEALGIE_00890 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPEALGIE_00891 4.1e-53 K peptidyl-tyrosine sulfation
JPEALGIE_00895 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JPEALGIE_00896 3.9e-19 IQ Acetoin reductase
JPEALGIE_00897 6.8e-51 IQ Acetoin reductase
JPEALGIE_00898 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JPEALGIE_00899 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JPEALGIE_00900 1.9e-152 XK27_05470 E Methionine synthase
JPEALGIE_00901 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JPEALGIE_00902 6.9e-251 T PhoQ Sensor
JPEALGIE_00903 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPEALGIE_00904 5.1e-153 S TraX protein
JPEALGIE_00905 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JPEALGIE_00906 2.4e-158 dprA LU DNA protecting protein DprA
JPEALGIE_00907 1.1e-167 GK ROK family
JPEALGIE_00908 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPEALGIE_00909 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JPEALGIE_00910 6.9e-127 K DNA-binding helix-turn-helix protein
JPEALGIE_00911 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
JPEALGIE_00912 2.4e-87 niaX
JPEALGIE_00913 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JPEALGIE_00914 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JPEALGIE_00915 2e-126 gntR1 K transcriptional
JPEALGIE_00916 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JPEALGIE_00917 2.3e-176 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPEALGIE_00918 1.8e-111 L PFAM Integrase, catalytic core
JPEALGIE_00919 3.3e-09 L PFAM Integrase, catalytic core
JPEALGIE_00920 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
JPEALGIE_00921 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
JPEALGIE_00922 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
JPEALGIE_00924 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
JPEALGIE_00925 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
JPEALGIE_00927 5.7e-217 S MvaI/BcnI restriction endonuclease family
JPEALGIE_00929 7.7e-13
JPEALGIE_00930 5e-31 S Hypothetical protein (DUF2513)
JPEALGIE_00931 6.5e-31
JPEALGIE_00932 1e-39
JPEALGIE_00937 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
JPEALGIE_00938 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPEALGIE_00939 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
JPEALGIE_00940 3.3e-46 K Putative DNA-binding domain
JPEALGIE_00941 0.0 res_1 3.1.21.5 S Type III restriction
JPEALGIE_00942 1.1e-20
JPEALGIE_00944 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
JPEALGIE_00945 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
JPEALGIE_00946 3.1e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPEALGIE_00947 1.4e-158 aatB ET ABC transporter substrate-binding protein
JPEALGIE_00948 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_00949 5.3e-105 artQ P ABC transporter (Permease
JPEALGIE_00950 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
JPEALGIE_00951 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JPEALGIE_00952 4.5e-166 cpsY K Transcriptional regulator
JPEALGIE_00953 6.6e-71 L transposition
JPEALGIE_00954 1.9e-119 mur1 NU muramidase
JPEALGIE_00955 1.5e-170 yeiH S Membrane
JPEALGIE_00956 1.7e-08
JPEALGIE_00957 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
JPEALGIE_00958 3.7e-88 XK27_10720 D peptidase activity
JPEALGIE_00959 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
JPEALGIE_00960 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
JPEALGIE_00961 2.9e-154 glcU U Glucose uptake
JPEALGIE_00962 5.2e-113 hsdM 2.1.1.72 V type I restriction-modification system
JPEALGIE_00963 5.2e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
JPEALGIE_00964 6.3e-54 L Transposase
JPEALGIE_00965 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
JPEALGIE_00966 3.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JPEALGIE_00967 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JPEALGIE_00968 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JPEALGIE_00969 0.0 copB 3.6.3.4 P P-type ATPase
JPEALGIE_00970 9.4e-43 K Cold-Shock Protein
JPEALGIE_00971 5.4e-32 cspD K Cold shock protein domain
JPEALGIE_00972 5.8e-41 pepD E dipeptidase activity
JPEALGIE_00973 8e-90 pepD E Dipeptidase
JPEALGIE_00974 8.7e-162 whiA K May be required for sporulation
JPEALGIE_00975 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JPEALGIE_00976 1.2e-163 rapZ S Displays ATPase and GTPase activities
JPEALGIE_00977 5.3e-136 yejC S cyclic nucleotide-binding protein
JPEALGIE_00978 4.2e-18 D nuclear chromosome segregation
JPEALGIE_00979 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JPEALGIE_00980 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JPEALGIE_00981 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JPEALGIE_00982 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JPEALGIE_00983 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
JPEALGIE_00984 3e-13
JPEALGIE_00985 2.4e-30
JPEALGIE_00986 1.5e-07
JPEALGIE_00987 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JPEALGIE_00988 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JPEALGIE_00989 3.1e-81 ypmB S Protein conserved in bacteria
JPEALGIE_00990 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JPEALGIE_00991 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JPEALGIE_00992 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
JPEALGIE_00993 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
JPEALGIE_00994 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JPEALGIE_00995 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JPEALGIE_00996 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JPEALGIE_00997 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JPEALGIE_00998 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JPEALGIE_00999 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JPEALGIE_01000 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
JPEALGIE_01001 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
JPEALGIE_01002 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
JPEALGIE_01003 2.1e-30 rpsT J rRNA binding
JPEALGIE_01004 9.2e-110 T PhoQ Sensor
JPEALGIE_01005 4.3e-41 T PhoQ Sensor
JPEALGIE_01006 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPEALGIE_01007 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JPEALGIE_01008 6.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
JPEALGIE_01009 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JPEALGIE_01010 1.6e-92 panT S ECF transporter, substrate-specific component
JPEALGIE_01011 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JPEALGIE_01012 7.3e-166 metF 1.5.1.20 C reductase
JPEALGIE_01013 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JPEALGIE_01015 7.1e-217 sip L Belongs to the 'phage' integrase family
JPEALGIE_01016 6e-39 K Helix-turn-helix
JPEALGIE_01017 5.5e-17 K TRANSCRIPTIONal
JPEALGIE_01022 6.9e-22
JPEALGIE_01023 3e-164 KL Phage plasmid primase P4 family
JPEALGIE_01024 2e-296 S DNA primase
JPEALGIE_01026 2.3e-12
JPEALGIE_01028 2e-103
JPEALGIE_01029 1.4e-66 S tRNA_anti-like
JPEALGIE_01030 4e-22 L Belongs to the 'phage' integrase family
JPEALGIE_01031 3e-44 ymbI L transposase activity
JPEALGIE_01032 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
JPEALGIE_01033 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
JPEALGIE_01034 5.1e-106 V Abi-like protein
JPEALGIE_01035 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
JPEALGIE_01036 1.1e-151 3.6.3.8 P cation transport ATPase
JPEALGIE_01037 0.0 3.6.3.8 P cation transport ATPase
JPEALGIE_01038 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JPEALGIE_01039 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPEALGIE_01040 4.6e-238 dltB M Membrane protein involved in D-alanine export
JPEALGIE_01041 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPEALGIE_01042 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
JPEALGIE_01043 0.0 XK27_10035 V abc transporter atp-binding protein
JPEALGIE_01044 0.0 yfiB1 V abc transporter atp-binding protein
JPEALGIE_01045 2.4e-107 pvaA M lytic transglycosylase activity
JPEALGIE_01046 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
JPEALGIE_01047 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JPEALGIE_01048 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JPEALGIE_01049 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JPEALGIE_01050 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JPEALGIE_01051 4.5e-111 tdk 2.7.1.21 F thymidine kinase
JPEALGIE_01052 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JPEALGIE_01053 8.9e-155 gst O Glutathione S-transferase
JPEALGIE_01054 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
JPEALGIE_01055 1.9e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JPEALGIE_01056 2e-45 rpmE2 J 50S ribosomal protein L31
JPEALGIE_01057 8.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
JPEALGIE_01059 3.2e-45 L Transposase
JPEALGIE_01060 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JPEALGIE_01061 3.3e-134 divIVA D Cell division protein DivIVA
JPEALGIE_01062 4.7e-143 ylmH T S4 RNA-binding domain
JPEALGIE_01063 8.8e-35 yggT D integral membrane protein
JPEALGIE_01064 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JPEALGIE_01065 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JPEALGIE_01066 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JPEALGIE_01067 1.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JPEALGIE_01068 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JPEALGIE_01069 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JPEALGIE_01070 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JPEALGIE_01072 0.0 typA T GTP-binding protein TypA
JPEALGIE_01073 1.6e-177 glk 2.7.1.2 G Glucokinase
JPEALGIE_01074 8.4e-28 yqgQ S protein conserved in bacteria
JPEALGIE_01075 1.1e-80 perR P Belongs to the Fur family
JPEALGIE_01076 1.6e-91 dps P Belongs to the Dps family
JPEALGIE_01077 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JPEALGIE_01078 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
JPEALGIE_01079 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
JPEALGIE_01080 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
JPEALGIE_01081 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JPEALGIE_01082 6.2e-56 S Domain of unknown function (DUF4430)
JPEALGIE_01083 5.1e-73 S Psort location CytoplasmicMembrane, score
JPEALGIE_01084 1.8e-135 htpX O Belongs to the peptidase M48B family
JPEALGIE_01085 1.5e-92 lemA S LemA family
JPEALGIE_01086 8.8e-157 spd F DNA RNA non-specific endonuclease
JPEALGIE_01087 3e-38
JPEALGIE_01088 2.5e-44
JPEALGIE_01090 9.3e-68 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
JPEALGIE_01091 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
JPEALGIE_01092 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
JPEALGIE_01093 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPEALGIE_01094 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPEALGIE_01095 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
JPEALGIE_01096 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
JPEALGIE_01097 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPEALGIE_01098 2.1e-27 P Hemerythrin HHE cation binding domain protein
JPEALGIE_01099 2.2e-144 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
JPEALGIE_01100 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JPEALGIE_01101 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
JPEALGIE_01102 9.8e-174 S hydrolase
JPEALGIE_01103 5.9e-16
JPEALGIE_01104 1.5e-154 M LysM domain
JPEALGIE_01105 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JPEALGIE_01106 1.2e-33 S SIR2-like domain
JPEALGIE_01107 5.2e-29 S SIR2-like domain
JPEALGIE_01108 1.2e-224 mutH L DNA mismatch repair enzyme MutH
JPEALGIE_01109 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
JPEALGIE_01110 4.8e-11
JPEALGIE_01111 7.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
JPEALGIE_01112 1.1e-33 XK27_12190 S protein conserved in bacteria
JPEALGIE_01114 8.4e-88 bioY S biotin synthase
JPEALGIE_01115 8.1e-46 S CHY zinc finger
JPEALGIE_01116 3.4e-252 yegQ O Peptidase U32
JPEALGIE_01117 2e-177 yegQ O Peptidase U32
JPEALGIE_01119 5.5e-69 ytxH S General stress protein
JPEALGIE_01121 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JPEALGIE_01122 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JPEALGIE_01123 9.9e-42 pspC KT PspC domain
JPEALGIE_01124 0.0 yhgF K Transcriptional accessory protein
JPEALGIE_01126 1.2e-155 XK27_03015 S permease
JPEALGIE_01127 2.3e-145 ycgQ S TIGR03943 family
JPEALGIE_01128 9e-195 S CRISPR-associated protein Csn2 subfamily St
JPEALGIE_01129 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_01130 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPEALGIE_01131 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JPEALGIE_01132 1.1e-94
JPEALGIE_01133 4.8e-33 estA E GDSL-like Lipase/Acylhydrolase
JPEALGIE_01134 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
JPEALGIE_01135 1e-31 K Cro/C1-type HTH DNA-binding domain
JPEALGIE_01136 1.2e-45
JPEALGIE_01137 8.9e-20
JPEALGIE_01138 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPEALGIE_01139 4.5e-97 mip S hydroperoxide reductase activity
JPEALGIE_01140 7e-203 I acyl-CoA dehydrogenase
JPEALGIE_01141 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
JPEALGIE_01142 6.4e-252 msrR K Transcriptional regulator
JPEALGIE_01143 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
JPEALGIE_01144 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JPEALGIE_01145 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JPEALGIE_01146 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JPEALGIE_01147 3.2e-53 yheA S Belongs to the UPF0342 family
JPEALGIE_01148 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JPEALGIE_01149 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JPEALGIE_01150 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JPEALGIE_01151 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JPEALGIE_01152 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JPEALGIE_01153 2e-219 ywbD 2.1.1.191 J Methyltransferase
JPEALGIE_01154 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JPEALGIE_01155 2e-25 WQ51_00785
JPEALGIE_01156 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JPEALGIE_01157 1e-78 yueI S Protein of unknown function (DUF1694)
JPEALGIE_01158 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JPEALGIE_01159 6.6e-101 yyaQ V Protein conserved in bacteria
JPEALGIE_01160 2.8e-28 yyaQ S YjbR
JPEALGIE_01161 4.4e-183 ccpA K Catabolite control protein A
JPEALGIE_01162 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
JPEALGIE_01163 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
JPEALGIE_01164 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JPEALGIE_01165 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JPEALGIE_01166 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JPEALGIE_01167 2e-33 secG U Preprotein translocase subunit SecG
JPEALGIE_01168 2.5e-220 mdtG EGP Major facilitator Superfamily
JPEALGIE_01169 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JPEALGIE_01170 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JPEALGIE_01171 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JPEALGIE_01172 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JPEALGIE_01173 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JPEALGIE_01174 6.8e-53 licT K transcriptional antiterminator
JPEALGIE_01175 5.8e-64 licT K transcriptional antiterminator
JPEALGIE_01176 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JPEALGIE_01177 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
JPEALGIE_01178 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JPEALGIE_01179 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JPEALGIE_01180 7.5e-23 I Alpha/beta hydrolase family
JPEALGIE_01181 1.5e-35 yugF I carboxylic ester hydrolase activity
JPEALGIE_01182 2.2e-45 K sequence-specific DNA binding
JPEALGIE_01183 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JPEALGIE_01185 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JPEALGIE_01186 3.1e-78 feoA P FeoA domain protein
JPEALGIE_01187 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPEALGIE_01188 3.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
JPEALGIE_01189 1.3e-34 ykuJ S protein conserved in bacteria
JPEALGIE_01190 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JPEALGIE_01191 0.0 clpE O Belongs to the ClpA ClpB family
JPEALGIE_01192 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JPEALGIE_01193 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
JPEALGIE_01194 1.2e-65 S oxidoreductase
JPEALGIE_01195 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
JPEALGIE_01196 3.7e-70 M Pfam SNARE associated Golgi protein
JPEALGIE_01197 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
JPEALGIE_01198 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
JPEALGIE_01201 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
JPEALGIE_01204 4.8e-16 S Protein of unknown function (DUF2969)
JPEALGIE_01205 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
JPEALGIE_01206 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPEALGIE_01207 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPEALGIE_01208 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JPEALGIE_01209 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
JPEALGIE_01210 1.4e-29 S Domain of unknown function (DUF1912)
JPEALGIE_01211 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
JPEALGIE_01212 1.5e-250 mmuP E amino acid
JPEALGIE_01213 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JPEALGIE_01214 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JPEALGIE_01215 9.7e-22
JPEALGIE_01216 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JPEALGIE_01217 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JPEALGIE_01218 1.7e-218 mvaS 2.3.3.10 I synthase
JPEALGIE_01219 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JPEALGIE_01220 1e-25 K hmm pf08876
JPEALGIE_01221 1.1e-116 yqfA K protein, Hemolysin III
JPEALGIE_01222 1.6e-22 S Protein of unknown function (DUF3114)
JPEALGIE_01223 1.1e-161 S Protein of unknown function (DUF3114)
JPEALGIE_01224 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JPEALGIE_01225 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JPEALGIE_01226 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JPEALGIE_01227 5.5e-49 XK27_13030
JPEALGIE_01228 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JPEALGIE_01229 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
JPEALGIE_01230 4.2e-68 U protein secretion
JPEALGIE_01231 3e-29 U protein secretion
JPEALGIE_01233 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JPEALGIE_01234 2.5e-21
JPEALGIE_01235 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
JPEALGIE_01236 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JPEALGIE_01237 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JPEALGIE_01238 1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
JPEALGIE_01239 1.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JPEALGIE_01240 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JPEALGIE_01241 8.8e-104 GBS0088 J protein conserved in bacteria
JPEALGIE_01242 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JPEALGIE_01243 1.3e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JPEALGIE_01244 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
JPEALGIE_01245 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JPEALGIE_01246 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPEALGIE_01247 2.5e-113 S VIT family
JPEALGIE_01248 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
JPEALGIE_01249 1.9e-22
JPEALGIE_01250 8e-28 XK27_00085 K Transcriptional
JPEALGIE_01251 6.9e-197 yceA S Belongs to the UPF0176 family
JPEALGIE_01252 5.4e-122 sagI S ABC-2 type transporter
JPEALGIE_01253 2.8e-168 V ABC transporter
JPEALGIE_01254 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JPEALGIE_01255 2.5e-132 rr02 KT response regulator
JPEALGIE_01256 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JPEALGIE_01257 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JPEALGIE_01258 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JPEALGIE_01259 0.0 lmrA V abc transporter atp-binding protein
JPEALGIE_01260 0.0 mdlB V abc transporter atp-binding protein
JPEALGIE_01262 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JPEALGIE_01263 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JPEALGIE_01264 7.2e-24 ytrF V efflux transmembrane transporter activity
JPEALGIE_01265 4.6e-43 V efflux transmembrane transporter activity
JPEALGIE_01266 1.7e-59 V permease protein
JPEALGIE_01267 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JPEALGIE_01268 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JPEALGIE_01269 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
JPEALGIE_01270 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
JPEALGIE_01271 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
JPEALGIE_01272 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JPEALGIE_01273 3.7e-227 pyrP F uracil Permease
JPEALGIE_01274 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JPEALGIE_01275 2.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPEALGIE_01276 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JPEALGIE_01277 1.4e-167 fhuR K transcriptional regulator (lysR family)
JPEALGIE_01283 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JPEALGIE_01284 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
JPEALGIE_01285 9.4e-119 pts33BCA G pts system
JPEALGIE_01286 5.8e-71 pts33BCA G pts system
JPEALGIE_01287 4.8e-24 pts33BCA G pts system
JPEALGIE_01288 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
JPEALGIE_01289 1.8e-254 cycA E permease
JPEALGIE_01290 4.5e-39 ynzC S UPF0291 protein
JPEALGIE_01291 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JPEALGIE_01292 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JPEALGIE_01293 1.7e-32 S membrane
JPEALGIE_01294 1.2e-61
JPEALGIE_01295 4.4e-26
JPEALGIE_01296 7.4e-55
JPEALGIE_01297 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JPEALGIE_01298 1.5e-114 nptA P COG1283 Na phosphate symporter
JPEALGIE_01299 2.9e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
JPEALGIE_01300 9.2e-105 mur1 NU mannosyl-glycoprotein
JPEALGIE_01301 1.2e-52 glnB K Belongs to the P(II) protein family
JPEALGIE_01302 2.9e-232 amt P Ammonium Transporter
JPEALGIE_01303 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JPEALGIE_01304 9.5e-55 yabA L Involved in initiation control of chromosome replication
JPEALGIE_01305 1.2e-135 yaaT S stage 0 sporulation protein
JPEALGIE_01306 6.4e-162 holB 2.7.7.7 L dna polymerase iii
JPEALGIE_01307 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JPEALGIE_01308 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JPEALGIE_01309 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JPEALGIE_01310 2.8e-230 ftsW D Belongs to the SEDS family
JPEALGIE_01311 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JPEALGIE_01312 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JPEALGIE_01313 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JPEALGIE_01314 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JPEALGIE_01315 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPEALGIE_01316 3.3e-78 atpF C ATP synthase F(0) sector subunit b
JPEALGIE_01317 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
JPEALGIE_01318 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPEALGIE_01319 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JPEALGIE_01320 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JPEALGIE_01321 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JPEALGIE_01322 8.9e-14 coiA 3.6.4.12 S Competence protein
JPEALGIE_01323 2.9e-15 T peptidase
JPEALGIE_01324 1.4e-151 rarD S Transporter
JPEALGIE_01325 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JPEALGIE_01326 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JPEALGIE_01327 2.2e-130 yxkH G deacetylase
JPEALGIE_01328 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JPEALGIE_01329 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JPEALGIE_01330 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JPEALGIE_01331 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JPEALGIE_01332 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
JPEALGIE_01333 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JPEALGIE_01334 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
JPEALGIE_01335 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPEALGIE_01336 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPEALGIE_01337 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JPEALGIE_01338 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
JPEALGIE_01339 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
JPEALGIE_01340 0.0 pepF E oligoendopeptidase F
JPEALGIE_01341 1.4e-186 coiA 3.6.4.12 S Competence protein
JPEALGIE_01342 1.8e-164 K transcriptional regulator (lysR family)
JPEALGIE_01343 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JPEALGIE_01347 8e-191 phoH T phosphate starvation-inducible protein PhoH
JPEALGIE_01348 2.3e-61 rlpA M LysM domain protein
JPEALGIE_01349 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
JPEALGIE_01350 7.4e-35 yozE S Belongs to the UPF0346 family
JPEALGIE_01351 1.7e-159 cvfB S Protein conserved in bacteria
JPEALGIE_01352 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JPEALGIE_01353 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JPEALGIE_01354 1.3e-120 sptS 2.7.13.3 T Histidine kinase
JPEALGIE_01355 1.4e-45 K Acetyltransferase (GNAT) family
JPEALGIE_01356 0.0 lmrA2 V abc transporter atp-binding protein
JPEALGIE_01357 0.0 lmrA1 V abc transporter atp-binding protein
JPEALGIE_01358 1.9e-77 K DNA-binding transcription factor activity
JPEALGIE_01359 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JPEALGIE_01360 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JPEALGIE_01361 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
JPEALGIE_01362 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
JPEALGIE_01363 7.2e-25 U response to pH
JPEALGIE_01364 0.0 yfmR S abc transporter atp-binding protein
JPEALGIE_01365 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JPEALGIE_01366 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JPEALGIE_01367 9.8e-91 XK27_08360 S EDD domain protein, DegV family
JPEALGIE_01368 2.6e-64 WQ51_03320 S cog cog4835
JPEALGIE_01369 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JPEALGIE_01370 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JPEALGIE_01371 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JPEALGIE_01372 6.4e-29 2.3.1.128 K acetyltransferase
JPEALGIE_01373 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JPEALGIE_01374 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JPEALGIE_01375 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JPEALGIE_01376 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JPEALGIE_01378 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JPEALGIE_01379 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JPEALGIE_01380 0.0 fruA 2.7.1.202 G phosphotransferase system
JPEALGIE_01381 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JPEALGIE_01382 5.5e-122 fruR K transcriptional
JPEALGIE_01383 8.9e-84 L Transposase
JPEALGIE_01384 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
JPEALGIE_01385 6.6e-38 L transposase activity
JPEALGIE_01386 1.2e-61 L transposition
JPEALGIE_01387 2.5e-59 L COG2801 Transposase and inactivated derivatives
JPEALGIE_01388 1.1e-113 K sequence-specific DNA binding
JPEALGIE_01389 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
JPEALGIE_01390 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
JPEALGIE_01391 7.7e-198 V (ABC) transporter
JPEALGIE_01392 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
JPEALGIE_01393 1.1e-176 S Protein of unknown function (DUF3114)
JPEALGIE_01394 2.7e-82 S Protein of unknown function (DUF3114)
JPEALGIE_01396 1.1e-65 tnp L Transposase
JPEALGIE_01397 4.7e-27 L Transposase and inactivated derivatives, TnpA family
JPEALGIE_01398 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
JPEALGIE_01399 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
JPEALGIE_01400 1.1e-65 tnp L Transposase
JPEALGIE_01401 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JPEALGIE_01402 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JPEALGIE_01403 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JPEALGIE_01404 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JPEALGIE_01405 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JPEALGIE_01406 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JPEALGIE_01407 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JPEALGIE_01408 1.6e-126 IQ reductase
JPEALGIE_01409 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JPEALGIE_01410 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
JPEALGIE_01411 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JPEALGIE_01412 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JPEALGIE_01413 4e-72 marR K Transcriptional regulator, MarR family
JPEALGIE_01414 6.9e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
JPEALGIE_01415 1.6e-114 S Haloacid dehalogenase-like hydrolase
JPEALGIE_01416 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
JPEALGIE_01417 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
JPEALGIE_01418 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPEALGIE_01419 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
JPEALGIE_01420 1.3e-101 ygaC J Belongs to the UPF0374 family
JPEALGIE_01421 6.4e-108 S Domain of unknown function (DUF1803)
JPEALGIE_01422 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
JPEALGIE_01429 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JPEALGIE_01430 1.7e-122 comFC S Competence protein
JPEALGIE_01431 5.9e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JPEALGIE_01432 1.1e-110 yvyE 3.4.13.9 S YigZ family
JPEALGIE_01433 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JPEALGIE_01434 8.9e-41 acuB S IMP dehydrogenase activity
JPEALGIE_01435 6.8e-69 acuB S IMP dehydrogenase activity
JPEALGIE_01436 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JPEALGIE_01437 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JPEALGIE_01438 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
JPEALGIE_01439 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
JPEALGIE_01440 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JPEALGIE_01441 7.1e-46 ylbG S UPF0298 protein
JPEALGIE_01442 1.2e-74 ylbF S Belongs to the UPF0342 family
JPEALGIE_01443 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JPEALGIE_01444 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JPEALGIE_01447 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JPEALGIE_01448 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
JPEALGIE_01449 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
JPEALGIE_01450 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
JPEALGIE_01451 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JPEALGIE_01452 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
JPEALGIE_01453 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
JPEALGIE_01455 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
JPEALGIE_01456 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
JPEALGIE_01457 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JPEALGIE_01458 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JPEALGIE_01459 1.4e-41 ylxQ J ribosomal protein
JPEALGIE_01460 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
JPEALGIE_01461 3.1e-212 nusA K Participates in both transcription termination and antitermination
JPEALGIE_01462 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
JPEALGIE_01463 2.5e-220 brpA K Transcriptional
JPEALGIE_01464 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
JPEALGIE_01465 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
JPEALGIE_01466 2.5e-248 pbuO S permease
JPEALGIE_01467 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JPEALGIE_01468 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
JPEALGIE_01469 1.1e-181 manL 2.7.1.191 G pts system
JPEALGIE_01470 5e-108 manM G pts system
JPEALGIE_01471 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
JPEALGIE_01472 4.2e-62 manO S protein conserved in bacteria
JPEALGIE_01473 8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JPEALGIE_01474 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JPEALGIE_01475 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JPEALGIE_01476 4.1e-09 S Domain of unknown function (DUF4651)
JPEALGIE_01477 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JPEALGIE_01478 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPEALGIE_01479 2.6e-68 yeeE S Sulphur transport
JPEALGIE_01480 2e-109 yeeE S Sulphur transport
JPEALGIE_01481 1.9e-36 yeeD O sulfur carrier activity
JPEALGIE_01482 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JPEALGIE_01483 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JPEALGIE_01486 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
JPEALGIE_01487 1.5e-64 S phosphatase activity
JPEALGIE_01488 1.9e-46 S glycolate biosynthetic process
JPEALGIE_01489 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JPEALGIE_01490 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JPEALGIE_01491 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JPEALGIE_01492 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JPEALGIE_01493 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JPEALGIE_01494 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JPEALGIE_01495 1.3e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
JPEALGIE_01496 2.5e-116 fnt P Formate nitrite transporter
JPEALGIE_01497 1.5e-220 XK27_09615 C reductase
JPEALGIE_01498 6.2e-76 XK27_09620 S reductase
JPEALGIE_01499 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
JPEALGIE_01500 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JPEALGIE_01501 1.8e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JPEALGIE_01502 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
JPEALGIE_01503 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
JPEALGIE_01504 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
JPEALGIE_01505 1.4e-32 M the current gene model (or a revised gene model) may contain a
JPEALGIE_01506 2.6e-94 L Integrase core domain
JPEALGIE_01507 1.4e-36 L Integrase core domain
JPEALGIE_01508 2.6e-49 3.2.1.4 GH5,GH9 M domain protein
JPEALGIE_01509 2.1e-12 G gluconolactonase activity
JPEALGIE_01510 1.3e-125 tnp L DDE domain
JPEALGIE_01511 5.9e-17 lytN 3.5.1.104 M LysM domain
JPEALGIE_01512 2.8e-160 L Transposase DDE domain
JPEALGIE_01513 4.3e-41 L Protein of unknown function (DUF3991)
JPEALGIE_01515 2.3e-32 L transposase activity
JPEALGIE_01516 5e-23 L Transposase
JPEALGIE_01517 2.6e-31 L transposition
JPEALGIE_01518 2.5e-23 L Transposase
JPEALGIE_01519 1.7e-54 L transposition
JPEALGIE_01520 3.4e-80 L PFAM Integrase catalytic region
JPEALGIE_01521 9e-88 yrdC 3.5.1.19 Q isochorismatase
JPEALGIE_01522 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JPEALGIE_01523 4e-167 dnaI L Primosomal protein DnaI
JPEALGIE_01524 5e-218 dnaB L Replication initiation and membrane attachment
JPEALGIE_01525 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JPEALGIE_01526 3.3e-275 T PhoQ Sensor
JPEALGIE_01527 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPEALGIE_01528 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
JPEALGIE_01529 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
JPEALGIE_01530 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
JPEALGIE_01531 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
JPEALGIE_01532 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
JPEALGIE_01533 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JPEALGIE_01534 1.2e-146 cbiQ P cobalt transport
JPEALGIE_01535 0.0 ykoD P abc transporter atp-binding protein
JPEALGIE_01536 8e-94 S UPF0397 protein
JPEALGIE_01537 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
JPEALGIE_01538 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JPEALGIE_01539 5.2e-98 metI P ABC transporter (Permease
JPEALGIE_01540 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JPEALGIE_01541 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
JPEALGIE_01542 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
JPEALGIE_01543 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JPEALGIE_01544 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
JPEALGIE_01545 1.8e-153 ET amino acid transport
JPEALGIE_01546 3.8e-205 EGP Transmembrane secretion effector
JPEALGIE_01547 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
JPEALGIE_01548 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPEALGIE_01549 5.3e-153 ET amino acid transport
JPEALGIE_01550 1.6e-131 cbiO P ABC transporter
JPEALGIE_01551 1.1e-136 P cobalt transport protein
JPEALGIE_01552 4.3e-175 cbiM P PDGLE domain
JPEALGIE_01553 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JPEALGIE_01554 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JPEALGIE_01555 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JPEALGIE_01556 6.6e-78 ureE O enzyme active site formation
JPEALGIE_01557 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JPEALGIE_01558 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JPEALGIE_01559 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JPEALGIE_01560 6.8e-95 ureI S AmiS/UreI family transporter
JPEALGIE_01561 2.1e-105 S Domain of unknown function (DUF4173)
JPEALGIE_01562 1.8e-50 yhaI L Membrane
JPEALGIE_01563 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPEALGIE_01564 1.8e-34 V protein secretion by the type I secretion system
JPEALGIE_01565 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPEALGIE_01566 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPEALGIE_01567 1.2e-32 V protein secretion by the type I secretion system
JPEALGIE_01568 5.6e-161 K sequence-specific DNA binding
JPEALGIE_01569 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
JPEALGIE_01570 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JPEALGIE_01571 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JPEALGIE_01572 1.3e-246 trkA P Potassium transporter peripheral membrane component
JPEALGIE_01573 1.2e-258 trkH P Cation transport protein
JPEALGIE_01574 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JPEALGIE_01575 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPEALGIE_01576 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JPEALGIE_01577 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JPEALGIE_01578 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JPEALGIE_01579 7.8e-85 ykuL S CBS domain
JPEALGIE_01580 3.5e-99 XK27_09740 S Phosphoesterase
JPEALGIE_01581 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JPEALGIE_01582 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JPEALGIE_01583 7.6e-36 yneF S UPF0154 protein
JPEALGIE_01584 3.7e-91 K transcriptional regulator
JPEALGIE_01585 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JPEALGIE_01588 8.8e-98 ybhL S Belongs to the BI1 family
JPEALGIE_01589 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
JPEALGIE_01590 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPEALGIE_01591 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JPEALGIE_01592 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPEALGIE_01593 5.2e-59 L Integrase core domain protein
JPEALGIE_01594 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JPEALGIE_01595 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JPEALGIE_01596 2.1e-82 XK27_09675 K -acetyltransferase
JPEALGIE_01597 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JPEALGIE_01598 2.5e-23
JPEALGIE_01599 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
JPEALGIE_01600 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JPEALGIE_01601 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JPEALGIE_01602 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JPEALGIE_01603 8.9e-95 ypsA S Belongs to the UPF0398 family
JPEALGIE_01604 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JPEALGIE_01605 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPEALGIE_01606 3.8e-205 EGP Transmembrane secretion effector
JPEALGIE_01607 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
JPEALGIE_01608 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPEALGIE_01609 1.1e-30 ET amino acid transport
JPEALGIE_01610 5.1e-259 pepC 3.4.22.40 E aminopeptidase
JPEALGIE_01611 1.9e-77 yhaI L Membrane
JPEALGIE_01612 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JPEALGIE_01613 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JPEALGIE_01614 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
JPEALGIE_01615 2.6e-76 S thiolester hydrolase activity
JPEALGIE_01617 3.8e-40 K transcriptional
JPEALGIE_01619 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPEALGIE_01620 1.6e-137 glcR K transcriptional regulator (DeoR family)
JPEALGIE_01621 6.2e-35 cof Q phosphatase activity
JPEALGIE_01622 6e-55 cof Q phosphatase activity
JPEALGIE_01623 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
JPEALGIE_01624 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
JPEALGIE_01625 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
JPEALGIE_01626 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JPEALGIE_01627 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPEALGIE_01628 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPEALGIE_01629 6.8e-56 S TM2 domain
JPEALGIE_01630 4.7e-43
JPEALGIE_01632 3.2e-10 L transposase activity
JPEALGIE_01633 4.4e-37 L Transposase
JPEALGIE_01634 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JPEALGIE_01635 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JPEALGIE_01636 5.2e-142 cmpC S abc transporter atp-binding protein
JPEALGIE_01637 0.0 WQ51_06230 S ABC transporter substrate binding protein
JPEALGIE_01638 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JPEALGIE_01639 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JPEALGIE_01640 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
JPEALGIE_01641 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JPEALGIE_01642 9.8e-50 yajC U protein transport
JPEALGIE_01643 1.9e-127 yeeN K transcriptional regulatory protein
JPEALGIE_01644 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
JPEALGIE_01645 6.6e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
JPEALGIE_01646 4.8e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JPEALGIE_01647 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
JPEALGIE_01648 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
JPEALGIE_01649 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JPEALGIE_01650 1.6e-127 adcB P ABC transporter (Permease
JPEALGIE_01651 8.3e-136 adcC P ABC transporter, ATP-binding protein
JPEALGIE_01652 3.1e-72 adcR K transcriptional
JPEALGIE_01653 9.4e-223 EGP Major facilitator Superfamily
JPEALGIE_01654 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JPEALGIE_01655 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JPEALGIE_01656 6.4e-23
JPEALGIE_01657 3.4e-62 oppF P Belongs to the ABC transporter superfamily
JPEALGIE_01658 7.5e-62 oppF P Belongs to the ABC transporter superfamily
JPEALGIE_01659 2.7e-41 oppD P Belongs to the ABC transporter superfamily
JPEALGIE_01660 1.2e-62 oppD P Belongs to the ABC transporter superfamily
JPEALGIE_01661 2.5e-32 oppD P Belongs to the ABC transporter superfamily
JPEALGIE_01662 3e-27 oppD P Belongs to the ABC transporter superfamily
JPEALGIE_01663 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPEALGIE_01664 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPEALGIE_01665 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPEALGIE_01666 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPEALGIE_01667 2e-138 oppA E ABC transporter substrate-binding protein
JPEALGIE_01668 7e-10 oppA E ABC transporter substrate-binding protein
JPEALGIE_01669 2.2e-273 sufB O assembly protein SufB
JPEALGIE_01670 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
JPEALGIE_01671 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JPEALGIE_01672 6.3e-235 sufD O assembly protein SufD
JPEALGIE_01673 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JPEALGIE_01674 5.5e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
JPEALGIE_01675 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JPEALGIE_01676 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JPEALGIE_01677 5.8e-275 glnP P ABC transporter
JPEALGIE_01678 1e-123 glnQ E abc transporter atp-binding protein
JPEALGIE_01679 5e-94 V VanZ like family
JPEALGIE_01680 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JPEALGIE_01681 6.5e-202 yhjX P Major Facilitator
JPEALGIE_01682 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JPEALGIE_01683 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JPEALGIE_01684 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JPEALGIE_01685 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPEALGIE_01686 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPEALGIE_01687 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPEALGIE_01688 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPEALGIE_01689 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JPEALGIE_01690 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JPEALGIE_01691 3.8e-81 nrdI F Belongs to the NrdI family
JPEALGIE_01692 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPEALGIE_01693 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPEALGIE_01694 1.4e-42 F nucleotide catabolic process
JPEALGIE_01695 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JPEALGIE_01696 2e-177 prmA J Ribosomal protein L11 methyltransferase
JPEALGIE_01697 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
JPEALGIE_01698 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
JPEALGIE_01699 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JPEALGIE_01700 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JPEALGIE_01701 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JPEALGIE_01702 4.6e-149 ykuT M mechanosensitive ion channel
JPEALGIE_01703 1.6e-77 sigH K DNA-templated transcription, initiation
JPEALGIE_01704 6.5e-87
JPEALGIE_01705 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JPEALGIE_01706 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JPEALGIE_01707 9.9e-19 S Domain of unknown function (DUF4649)
JPEALGIE_01717 9.2e-51 S Protein of unknown function (DUF3397)
JPEALGIE_01718 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JPEALGIE_01719 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JPEALGIE_01720 7.3e-69 amiA E transmembrane transport
JPEALGIE_01721 6.7e-81 amiA E transmembrane transport
JPEALGIE_01722 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JPEALGIE_01723 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JPEALGIE_01724 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
JPEALGIE_01725 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JPEALGIE_01726 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPEALGIE_01727 2e-186 jag S RNA-binding protein
JPEALGIE_01728 1e-13 rpmH J Ribosomal protein L34
JPEALGIE_01729 1.1e-83 L Transposase
JPEALGIE_01730 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JPEALGIE_01731 1.7e-60 hmpT S membrane
JPEALGIE_01732 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
JPEALGIE_01733 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JPEALGIE_01734 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JPEALGIE_01735 9.8e-298 dnaK O Heat shock 70 kDa protein
JPEALGIE_01736 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JPEALGIE_01737 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JPEALGIE_01738 1.3e-102 acmA 3.2.1.17 NU amidase activity
JPEALGIE_01739 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JPEALGIE_01740 2.2e-38 ais G alpha-ribazole phosphatase activity
JPEALGIE_01741 1.9e-242 XK27_08635 S UPF0210 protein
JPEALGIE_01742 3.6e-39 gcvR T UPF0237 protein
JPEALGIE_01743 3.3e-225 capA M Bacterial capsule synthesis protein
JPEALGIE_01744 5.7e-91 tnp L Transposase
JPEALGIE_01745 3.4e-75 isp2 S pathogenesis
JPEALGIE_01747 4.9e-173
JPEALGIE_01748 1.8e-38 S Helix-turn-helix domain
JPEALGIE_01749 2.2e-224 int L Belongs to the 'phage' integrase family
JPEALGIE_01751 0.0 res_1 3.1.21.5 S Type III restriction
JPEALGIE_01752 9.7e-227 sthIM 2.1.1.72 L DNA methylase
JPEALGIE_01755 5.3e-18 D FtsK/SpoIIIE family
JPEALGIE_01756 1.3e-134 D ftsk spoiiie
JPEALGIE_01758 1.3e-154
JPEALGIE_01759 1.7e-22
JPEALGIE_01760 9.3e-184 L Phage integrase family
JPEALGIE_01761 6.5e-90 3.6.4.12 K Divergent AAA domain protein
JPEALGIE_01762 5.9e-24 3.6.4.12
JPEALGIE_01763 2.5e-183 EGP Major facilitator Superfamily
JPEALGIE_01764 2.4e-231 spaC2 V Lanthionine synthetase C family protein
JPEALGIE_01765 0.0 S Lantibiotic dehydratase, C terminus
JPEALGIE_01767 1.5e-35 K sequence-specific DNA binding
JPEALGIE_01768 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JPEALGIE_01769 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JPEALGIE_01770 3.6e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPEALGIE_01771 1.6e-94 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPEALGIE_01772 2.3e-31 K helix-turn-helix
JPEALGIE_01773 3.4e-155 degV S DegV family
JPEALGIE_01774 3.5e-91 yacP S RNA-binding protein containing a PIN domain
JPEALGIE_01775 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPEALGIE_01778 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JPEALGIE_01779 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPEALGIE_01780 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
JPEALGIE_01781 4.5e-143 S SseB protein N-terminal domain
JPEALGIE_01782 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JPEALGIE_01783 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_01784 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_01785 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPEALGIE_01786 0.0 clpC O Belongs to the ClpA ClpB family
JPEALGIE_01787 2.4e-75 ctsR K Belongs to the CtsR family
JPEALGIE_01788 1.1e-83 S Putative small multi-drug export protein
JPEALGIE_01789 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JPEALGIE_01790 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
JPEALGIE_01793 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JPEALGIE_01794 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
JPEALGIE_01795 3.2e-40 L transposition
JPEALGIE_01796 1e-87 L Integrase core domain protein
JPEALGIE_01797 1.7e-96 S reductase
JPEALGIE_01798 1.8e-26 badR K DNA-binding transcription factor activity
JPEALGIE_01799 5.5e-36 XK27_02060 S Transglycosylase associated protein
JPEALGIE_01800 5.7e-222 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JPEALGIE_01801 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPEALGIE_01806 1.9e-07
JPEALGIE_01809 2.6e-10
JPEALGIE_01814 1.1e-65 spxA_2 1.20.4.1 P Belongs to the ArsC family
JPEALGIE_01815 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JPEALGIE_01816 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
JPEALGIE_01817 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
JPEALGIE_01818 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JPEALGIE_01820 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JPEALGIE_01822 1.2e-61 KT phosphorelay signal transduction system
JPEALGIE_01823 7e-34 S Protein of unknown function (DUF3021)
JPEALGIE_01824 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JPEALGIE_01825 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JPEALGIE_01826 8.2e-70 argR K Regulates arginine biosynthesis genes
JPEALGIE_01827 2.6e-09 L Transposase
JPEALGIE_01828 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JPEALGIE_01829 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JPEALGIE_01830 9.2e-141 1.1.1.169 H Ketopantoate reductase
JPEALGIE_01831 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JPEALGIE_01832 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JPEALGIE_01833 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
JPEALGIE_01834 2.3e-161 S CHAP domain
JPEALGIE_01835 1.4e-33 L Integrase core domain protein
JPEALGIE_01836 1.4e-48 L transposition
JPEALGIE_01837 4.8e-76 L transposase activity
JPEALGIE_01838 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JPEALGIE_01839 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JPEALGIE_01840 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JPEALGIE_01841 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JPEALGIE_01842 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JPEALGIE_01843 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JPEALGIE_01844 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JPEALGIE_01845 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JPEALGIE_01846 1e-142 recO L Involved in DNA repair and RecF pathway recombination
JPEALGIE_01847 2.9e-218 araT 2.6.1.1 E Aminotransferase
JPEALGIE_01848 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JPEALGIE_01849 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
JPEALGIE_01850 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JPEALGIE_01851 5.5e-139 mreC M Involved in formation and maintenance of cell shape
JPEALGIE_01857 5.3e-11
JPEALGIE_01869 1.9e-86 L Integrase core domain protein
JPEALGIE_01872 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
JPEALGIE_01873 2e-09 L thioesterase
JPEALGIE_01874 1.9e-141 S Macro domain protein
JPEALGIE_01875 1.1e-50 trxA O Belongs to the thioredoxin family
JPEALGIE_01876 1.6e-143 tatD L Hydrolase, tatd
JPEALGIE_01877 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JPEALGIE_01878 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JPEALGIE_01880 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JPEALGIE_01881 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JPEALGIE_01882 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
JPEALGIE_01883 6.9e-173 rmuC S RmuC domain protein
JPEALGIE_01884 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
JPEALGIE_01885 5.3e-142 purR 2.4.2.7 F operon repressor
JPEALGIE_01886 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JPEALGIE_01887 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JPEALGIE_01888 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JPEALGIE_01889 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JPEALGIE_01890 1.9e-86 L Integrase core domain protein
JPEALGIE_01891 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JPEALGIE_01892 3.1e-30
JPEALGIE_01893 1.5e-12
JPEALGIE_01894 1.3e-87 S Fusaric acid resistance protein-like
JPEALGIE_01895 8.5e-63 glnR K Transcriptional regulator
JPEALGIE_01896 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
JPEALGIE_01897 2.7e-40 pscB M CHAP domain protein
JPEALGIE_01898 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPEALGIE_01899 2.5e-33 ykzG S Belongs to the UPF0356 family
JPEALGIE_01900 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
JPEALGIE_01901 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JPEALGIE_01902 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JPEALGIE_01903 1.8e-114 azlC E AzlC protein
JPEALGIE_01904 8.8e-48 azlD E branched-chain amino acid
JPEALGIE_01905 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JPEALGIE_01906 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JPEALGIE_01907 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPEALGIE_01908 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JPEALGIE_01909 1e-93 cvpA S toxin biosynthetic process
JPEALGIE_01910 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JPEALGIE_01911 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JPEALGIE_01916 2.5e-230 mutY L A G-specific adenine glycosylase
JPEALGIE_01917 3.6e-41 XK27_05745
JPEALGIE_01918 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
JPEALGIE_01919 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JPEALGIE_01920 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JPEALGIE_01922 3.1e-124 XK27_01040 S Pfam PF06570
JPEALGIE_01923 2e-169 corA P COG0598 Mg2 and Co2 transporters
JPEALGIE_01924 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JPEALGIE_01927 7.7e-11 V 'abc transporter, ATP-binding protein
JPEALGIE_01930 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
JPEALGIE_01931 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
JPEALGIE_01932 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JPEALGIE_01933 3.4e-62 yqhY S protein conserved in bacteria
JPEALGIE_01934 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JPEALGIE_01935 1.7e-179 scrR K Transcriptional
JPEALGIE_01936 4.1e-291 scrB 3.2.1.26 GH32 G invertase
JPEALGIE_01937 0.0 scrA 2.7.1.211 G pts system
JPEALGIE_01938 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JPEALGIE_01939 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPEALGIE_01941 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JPEALGIE_01942 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JPEALGIE_01943 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JPEALGIE_01944 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JPEALGIE_01945 1.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JPEALGIE_01946 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JPEALGIE_01947 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JPEALGIE_01948 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
JPEALGIE_01949 2.9e-18 yebC M Membrane
JPEALGIE_01950 1.6e-79 yebC M Membrane
JPEALGIE_01951 3.5e-17 KT response to antibiotic
JPEALGIE_01952 8.5e-68 KT response to antibiotic
JPEALGIE_01953 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
JPEALGIE_01954 3.4e-57 liaI S membrane
JPEALGIE_01955 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JPEALGIE_01956 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JPEALGIE_01957 9.3e-122 S Protein of unknown function (DUF554)
JPEALGIE_01958 2.1e-129 ecsA_2 V abc transporter atp-binding protein
JPEALGIE_01959 9.2e-284 XK27_00765
JPEALGIE_01960 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JPEALGIE_01961 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JPEALGIE_01962 4.5e-18 D nuclear chromosome segregation
JPEALGIE_01963 2.8e-21 yhaI J Protein of unknown function (DUF805)
JPEALGIE_01964 3.4e-58
JPEALGIE_01965 2.2e-85
JPEALGIE_01966 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JPEALGIE_01967 8.1e-46 ftsL D cell division protein FtsL
JPEALGIE_01968 0.0 ftsI 3.4.16.4 M penicillin-binding protein
JPEALGIE_01969 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JPEALGIE_01970 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JPEALGIE_01972 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JPEALGIE_01973 2.4e-66 yutD J protein conserved in bacteria
JPEALGIE_01974 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JPEALGIE_01975 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
JPEALGIE_01977 0.0 mdlA V abc transporter atp-binding protein
JPEALGIE_01978 0.0 mdlB V abc transporter atp-binding protein
JPEALGIE_01979 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPEALGIE_01980 4e-235 mesE M Transport protein ComB
JPEALGIE_01982 1.4e-237 blpH 2.7.13.3 T protein histidine kinase activity
JPEALGIE_01983 4.4e-132 agrA KT phosphorelay signal transduction system
JPEALGIE_01986 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
JPEALGIE_01991 1.2e-165 L integrase core domain
JPEALGIE_01992 3.9e-122 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)