ORF_ID e_value Gene_name EC_number CAZy COGs Description
EEFEMGPG_00001 4.7e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EEFEMGPG_00002 5.1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EEFEMGPG_00003 2.4e-33 yaaA S S4 domain
EEFEMGPG_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EEFEMGPG_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
EEFEMGPG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EEFEMGPG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EEFEMGPG_00008 1.2e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00011 2.2e-182 yaaC S YaaC-like Protein
EEFEMGPG_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EEFEMGPG_00013 2.1e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EEFEMGPG_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EEFEMGPG_00015 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EEFEMGPG_00016 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EEFEMGPG_00017 3.7e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EEFEMGPG_00018 1.3e-09
EEFEMGPG_00019 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EEFEMGPG_00020 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EEFEMGPG_00021 2.9e-211 yaaH M Glycoside Hydrolase Family
EEFEMGPG_00022 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
EEFEMGPG_00023 3e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EEFEMGPG_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EEFEMGPG_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EEFEMGPG_00026 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EEFEMGPG_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
EEFEMGPG_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
EEFEMGPG_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
EEFEMGPG_00033 4.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EEFEMGPG_00034 3.1e-193 yaaN P Belongs to the TelA family
EEFEMGPG_00035 1.2e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EEFEMGPG_00036 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EEFEMGPG_00037 9.8e-55 yaaQ S protein conserved in bacteria
EEFEMGPG_00038 1.2e-71 yaaR S protein conserved in bacteria
EEFEMGPG_00039 1.6e-180 holB 2.7.7.7 L DNA polymerase III
EEFEMGPG_00040 8.8e-145 yaaT S stage 0 sporulation protein
EEFEMGPG_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
EEFEMGPG_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
EEFEMGPG_00043 1.4e-47 yazA L endonuclease containing a URI domain
EEFEMGPG_00044 6.9e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EEFEMGPG_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
EEFEMGPG_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEFEMGPG_00047 6.9e-144 tatD L hydrolase, TatD
EEFEMGPG_00048 1.8e-232 rpfB GH23 T protein conserved in bacteria
EEFEMGPG_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EEFEMGPG_00050 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EEFEMGPG_00051 1.4e-145 yabG S peptidase
EEFEMGPG_00052 7.8e-39 veg S protein conserved in bacteria
EEFEMGPG_00053 8.4e-27 sspF S DNA topological change
EEFEMGPG_00054 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EEFEMGPG_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EEFEMGPG_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EEFEMGPG_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EEFEMGPG_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EEFEMGPG_00059 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EEFEMGPG_00060 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EEFEMGPG_00061 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EEFEMGPG_00062 3.7e-40 yabK S Peptide ABC transporter permease
EEFEMGPG_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EEFEMGPG_00064 6.2e-91 spoVT K stage V sporulation protein
EEFEMGPG_00065 3.8e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_00066 1.1e-275 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EEFEMGPG_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EEFEMGPG_00068 1.9e-49 yabP S Sporulation protein YabP
EEFEMGPG_00069 1.3e-103 yabQ S spore cortex biosynthesis protein
EEFEMGPG_00070 4.1e-57 divIC D Septum formation initiator
EEFEMGPG_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EEFEMGPG_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EEFEMGPG_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
EEFEMGPG_00076 4.7e-185 KLT serine threonine protein kinase
EEFEMGPG_00077 1.1e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EEFEMGPG_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EEFEMGPG_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EEFEMGPG_00080 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EEFEMGPG_00081 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EEFEMGPG_00082 1.8e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EEFEMGPG_00083 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EEFEMGPG_00084 6.1e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EEFEMGPG_00085 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EEFEMGPG_00086 4.2e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EEFEMGPG_00087 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EEFEMGPG_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EEFEMGPG_00089 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EEFEMGPG_00090 4.5e-29 yazB K transcriptional
EEFEMGPG_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEFEMGPG_00092 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EEFEMGPG_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00095 1.3e-07
EEFEMGPG_00098 2e-08
EEFEMGPG_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00104 7.5e-77 ctsR K Belongs to the CtsR family
EEFEMGPG_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EEFEMGPG_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EEFEMGPG_00107 0.0 clpC O Belongs to the ClpA ClpB family
EEFEMGPG_00108 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EEFEMGPG_00109 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EEFEMGPG_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EEFEMGPG_00111 1.9e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EEFEMGPG_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EEFEMGPG_00113 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EEFEMGPG_00114 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
EEFEMGPG_00115 4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EEFEMGPG_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EEFEMGPG_00117 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEFEMGPG_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
EEFEMGPG_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
EEFEMGPG_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EEFEMGPG_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
EEFEMGPG_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EEFEMGPG_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EEFEMGPG_00124 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EEFEMGPG_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EEFEMGPG_00126 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
EEFEMGPG_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EEFEMGPG_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EEFEMGPG_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EEFEMGPG_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EEFEMGPG_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EEFEMGPG_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EEFEMGPG_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EEFEMGPG_00134 3.7e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EEFEMGPG_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EEFEMGPG_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EEFEMGPG_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
EEFEMGPG_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EEFEMGPG_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EEFEMGPG_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EEFEMGPG_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EEFEMGPG_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EEFEMGPG_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EEFEMGPG_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EEFEMGPG_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EEFEMGPG_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EEFEMGPG_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EEFEMGPG_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EEFEMGPG_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EEFEMGPG_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EEFEMGPG_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EEFEMGPG_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EEFEMGPG_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EEFEMGPG_00154 1.9e-23 rpmD J Ribosomal protein L30
EEFEMGPG_00155 4.1e-72 rplO J binds to the 23S rRNA
EEFEMGPG_00156 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EEFEMGPG_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EEFEMGPG_00158 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
EEFEMGPG_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EEFEMGPG_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EEFEMGPG_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EEFEMGPG_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EEFEMGPG_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EEFEMGPG_00164 4.7e-58 rplQ J Ribosomal protein L17
EEFEMGPG_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EEFEMGPG_00166 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EEFEMGPG_00167 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EEFEMGPG_00168 1.6e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EEFEMGPG_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EEFEMGPG_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EEFEMGPG_00171 6.9e-144 ybaJ Q Methyltransferase domain
EEFEMGPG_00172 3e-81 yizA S Damage-inducible protein DinB
EEFEMGPG_00173 6.5e-78 ybaK S Protein of unknown function (DUF2521)
EEFEMGPG_00174 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EEFEMGPG_00175 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EEFEMGPG_00176 7.6e-76 gerD
EEFEMGPG_00177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EEFEMGPG_00178 1.1e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
EEFEMGPG_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00182 1.6e-08
EEFEMGPG_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00186 1.9e-220 glcP G Major Facilitator Superfamily
EEFEMGPG_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEFEMGPG_00188 1.1e-178 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
EEFEMGPG_00189 7.6e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
EEFEMGPG_00190 4.6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EEFEMGPG_00191 3.7e-174 ybaS 1.1.1.58 S Na -dependent transporter
EEFEMGPG_00192 5.1e-115 ybbA S Putative esterase
EEFEMGPG_00193 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_00194 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_00195 2e-172 feuA P Iron-uptake system-binding protein
EEFEMGPG_00196 6.6e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EEFEMGPG_00197 1.9e-236 ybbC 3.2.1.52 S protein conserved in bacteria
EEFEMGPG_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EEFEMGPG_00199 7.5e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EEFEMGPG_00200 1.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_00201 4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EEFEMGPG_00202 7e-86 ybbJ J acetyltransferase
EEFEMGPG_00203 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EEFEMGPG_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_00210 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EEFEMGPG_00211 1.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EEFEMGPG_00212 5.7e-224 ybbR S protein conserved in bacteria
EEFEMGPG_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEFEMGPG_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EEFEMGPG_00215 3.8e-154 V ATPases associated with a variety of cellular activities
EEFEMGPG_00216 9.8e-107 S ABC-2 family transporter protein
EEFEMGPG_00217 7e-100 ybdN
EEFEMGPG_00218 1.9e-132 ybdO S Domain of unknown function (DUF4885)
EEFEMGPG_00219 3.9e-164 dkgB S Aldo/keto reductase family
EEFEMGPG_00220 1e-93 yxaC M effector of murein hydrolase
EEFEMGPG_00221 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_00222 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_00223 2.5e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EEFEMGPG_00224 1.8e-103 T Histidine kinase
EEFEMGPG_00225 4.9e-82 KT helix_turn_helix, Lux Regulon
EEFEMGPG_00226 3.5e-134 V ABC transporter, ATP-binding protein
EEFEMGPG_00227 3.1e-146 V ABC-2 type transporter
EEFEMGPG_00228 4.6e-123 V ABC-2 type transporter
EEFEMGPG_00229 4.4e-14
EEFEMGPG_00230 3.6e-59 bacT Q Thioesterase domain
EEFEMGPG_00231 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
EEFEMGPG_00232 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
EEFEMGPG_00233 4.6e-121 fabD 2.3.1.39 I PFAM Acyl transferase
EEFEMGPG_00234 0.0 Q Beta-ketoacyl synthase
EEFEMGPG_00235 0.0 Q Polyketide synthase modules and related proteins
EEFEMGPG_00236 1.5e-102 Q Flavin containing amine oxidoreductase
EEFEMGPG_00237 0.0 Q TIGRFAM amino acid adenylation domain
EEFEMGPG_00238 4.6e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
EEFEMGPG_00239 4.5e-77 S Domain of unknown function (DUF4879)
EEFEMGPG_00240 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
EEFEMGPG_00241 4.3e-108 yqeB
EEFEMGPG_00242 9.2e-40 ybyB
EEFEMGPG_00243 2.5e-292 ybeC E amino acid
EEFEMGPG_00244 5.4e-49 M PFAM Glycosyl transferase family 2
EEFEMGPG_00245 4.2e-161 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EEFEMGPG_00246 1.7e-259 glpT G -transporter
EEFEMGPG_00247 1.3e-16 S Protein of unknown function (DUF2651)
EEFEMGPG_00248 2.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EEFEMGPG_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EEFEMGPG_00251 1.3e-30
EEFEMGPG_00252 1.2e-82 K Helix-turn-helix XRE-family like proteins
EEFEMGPG_00253 3.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EEFEMGPG_00254 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EEFEMGPG_00255 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EEFEMGPG_00256 1.9e-86 ybfM S SNARE associated Golgi protein
EEFEMGPG_00257 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EEFEMGPG_00258 1.2e-42 ybfN
EEFEMGPG_00259 2.3e-192 yceA S Belongs to the UPF0176 family
EEFEMGPG_00260 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EEFEMGPG_00261 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EEFEMGPG_00262 6.1e-258 mmuP E amino acid
EEFEMGPG_00263 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EEFEMGPG_00264 9.3e-259 agcS E Sodium alanine symporter
EEFEMGPG_00265 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
EEFEMGPG_00266 3.2e-210 phoQ 2.7.13.3 T Histidine kinase
EEFEMGPG_00267 9.1e-170 glnL T Regulator
EEFEMGPG_00268 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EEFEMGPG_00269 2.5e-36 L Transposase
EEFEMGPG_00270 2.7e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EEFEMGPG_00271 1.5e-109 ydfN C nitroreductase
EEFEMGPG_00272 1.2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EEFEMGPG_00273 1.5e-62 mhqP S DoxX
EEFEMGPG_00274 7e-56 traF CO Thioredoxin
EEFEMGPG_00275 5.6e-62 ycbP S Protein of unknown function (DUF2512)
EEFEMGPG_00276 2.8e-78 sleB 3.5.1.28 M Cell wall
EEFEMGPG_00277 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EEFEMGPG_00278 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EEFEMGPG_00279 3.4e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EEFEMGPG_00280 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EEFEMGPG_00281 2e-208 ycbU E Selenocysteine lyase
EEFEMGPG_00282 1.2e-237 lmrB EGP the major facilitator superfamily
EEFEMGPG_00283 1.2e-100 yxaF K Transcriptional regulator
EEFEMGPG_00284 4.7e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EEFEMGPG_00285 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EEFEMGPG_00286 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
EEFEMGPG_00287 3.3e-172 yccK C Aldo keto reductase
EEFEMGPG_00288 5.1e-177 ycdA S Domain of unknown function (DUF5105)
EEFEMGPG_00289 3.3e-261 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_00290 3.7e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_00291 2e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
EEFEMGPG_00292 5.1e-188 S response regulator aspartate phosphatase
EEFEMGPG_00293 2.8e-140 IQ Enoyl-(Acyl carrier protein) reductase
EEFEMGPG_00294 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EEFEMGPG_00295 3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
EEFEMGPG_00296 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EEFEMGPG_00297 5.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EEFEMGPG_00298 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_00299 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EEFEMGPG_00300 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
EEFEMGPG_00301 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
EEFEMGPG_00302 9.7e-138 terC P Protein of unknown function (DUF475)
EEFEMGPG_00303 0.0 yceG S Putative component of 'biosynthetic module'
EEFEMGPG_00304 3.9e-193 yceH P Belongs to the TelA family
EEFEMGPG_00305 2.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
EEFEMGPG_00306 3.9e-229 proV 3.6.3.32 E glycine betaine
EEFEMGPG_00307 1.6e-138 opuAB P glycine betaine
EEFEMGPG_00308 3.1e-164 opuAC E glycine betaine
EEFEMGPG_00309 1e-212 amhX S amidohydrolase
EEFEMGPG_00310 2.4e-230 ycgA S Membrane
EEFEMGPG_00311 4.1e-81 ycgB
EEFEMGPG_00312 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
EEFEMGPG_00313 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EEFEMGPG_00314 8.1e-261 mdr EGP Major facilitator Superfamily
EEFEMGPG_00315 5.4e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_00316 5.2e-113 ycgF E Lysine exporter protein LysE YggA
EEFEMGPG_00317 1.3e-150 yqcI S YqcI/YcgG family
EEFEMGPG_00318 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_00319 7.6e-114 ycgI S Domain of unknown function (DUF1989)
EEFEMGPG_00320 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EEFEMGPG_00322 2.1e-108 tmrB S AAA domain
EEFEMGPG_00323 1.3e-150 4.2.1.118 G Xylose isomerase-like TIM barrel
EEFEMGPG_00324 1.4e-232 G COG0477 Permeases of the major facilitator superfamily
EEFEMGPG_00325 2.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EEFEMGPG_00326 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_00327 6.4e-54 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_00328 1.7e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EEFEMGPG_00329 1.1e-147 ycgL S Predicted nucleotidyltransferase
EEFEMGPG_00330 2.3e-170 ycgM E Proline dehydrogenase
EEFEMGPG_00331 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EEFEMGPG_00332 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEFEMGPG_00333 4.7e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
EEFEMGPG_00334 1.4e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EEFEMGPG_00335 1.5e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EEFEMGPG_00336 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
EEFEMGPG_00337 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EEFEMGPG_00338 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEFEMGPG_00339 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
EEFEMGPG_00340 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
EEFEMGPG_00341 9.2e-228 yciC S GTPases (G3E family)
EEFEMGPG_00342 3.9e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EEFEMGPG_00343 1.2e-73 yckC S membrane
EEFEMGPG_00344 2.2e-51 S Protein of unknown function (DUF2680)
EEFEMGPG_00345 4.4e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EEFEMGPG_00346 2.5e-68 nin S Competence protein J (ComJ)
EEFEMGPG_00347 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
EEFEMGPG_00348 2.8e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EEFEMGPG_00349 2.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EEFEMGPG_00350 2.6e-61 hxlR K transcriptional
EEFEMGPG_00351 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_00352 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_00353 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EEFEMGPG_00354 7.5e-140 srfAD Q thioesterase
EEFEMGPG_00355 1.6e-249 bamJ E Aminotransferase class I and II
EEFEMGPG_00356 7.2e-63 S YcxB-like protein
EEFEMGPG_00357 5e-168 ycxC EG EamA-like transporter family
EEFEMGPG_00358 9.1e-245 ycxD K GntR family transcriptional regulator
EEFEMGPG_00359 1.3e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EEFEMGPG_00360 1.6e-109 yczE S membrane
EEFEMGPG_00361 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EEFEMGPG_00362 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
EEFEMGPG_00363 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EEFEMGPG_00364 1.1e-158 bsdA K LysR substrate binding domain
EEFEMGPG_00365 1.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EEFEMGPG_00366 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EEFEMGPG_00367 2e-38 bsdD 4.1.1.61 S response to toxic substance
EEFEMGPG_00368 1.3e-76 yclD
EEFEMGPG_00369 3.2e-270 dtpT E amino acid peptide transporter
EEFEMGPG_00370 1.1e-282 yclG M Pectate lyase superfamily protein
EEFEMGPG_00372 3.5e-294 gerKA EG Spore germination protein
EEFEMGPG_00373 7.2e-236 gerKC S spore germination
EEFEMGPG_00374 3.9e-196 gerKB F Spore germination protein
EEFEMGPG_00375 1.7e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_00376 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EEFEMGPG_00377 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
EEFEMGPG_00378 7.7e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
EEFEMGPG_00379 1.6e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EEFEMGPG_00380 1.1e-217 yxeP 3.5.1.47 E hydrolase activity
EEFEMGPG_00381 1.6e-252 yxeQ S MmgE/PrpD family
EEFEMGPG_00382 5.6e-121 yclH P ABC transporter
EEFEMGPG_00383 8.2e-231 yclI V ABC transporter (permease) YclI
EEFEMGPG_00384 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_00385 4.9e-260 T PhoQ Sensor
EEFEMGPG_00386 1.9e-81 S aspartate phosphatase
EEFEMGPG_00388 3e-251 lysC 2.7.2.4 E Belongs to the aspartokinase family
EEFEMGPG_00389 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_00390 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_00391 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EEFEMGPG_00392 9.3e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EEFEMGPG_00393 1.1e-248 ycnB EGP Major facilitator Superfamily
EEFEMGPG_00394 2.1e-152 ycnC K Transcriptional regulator
EEFEMGPG_00395 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
EEFEMGPG_00396 1e-44 ycnE S Monooxygenase
EEFEMGPG_00397 1.1e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EEFEMGPG_00398 5.3e-259 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EEFEMGPG_00399 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEFEMGPG_00400 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EEFEMGPG_00401 3.6e-149 glcU U Glucose uptake
EEFEMGPG_00402 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_00403 7.8e-98 ycnI S protein conserved in bacteria
EEFEMGPG_00404 4.2e-300 ycnJ P protein, homolog of Cu resistance protein CopC
EEFEMGPG_00405 7.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EEFEMGPG_00406 1.6e-55
EEFEMGPG_00407 1.1e-224 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EEFEMGPG_00408 1.2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EEFEMGPG_00409 1.3e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EEFEMGPG_00410 3e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EEFEMGPG_00412 1e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EEFEMGPG_00413 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
EEFEMGPG_00414 1.8e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EEFEMGPG_00415 4.6e-151 ycsI S Belongs to the D-glutamate cyclase family
EEFEMGPG_00416 2.7e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EEFEMGPG_00417 4.6e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EEFEMGPG_00418 8.9e-131 kipR K Transcriptional regulator
EEFEMGPG_00419 1.1e-115 ycsK E anatomical structure formation involved in morphogenesis
EEFEMGPG_00421 1.6e-54 yczJ S biosynthesis
EEFEMGPG_00422 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EEFEMGPG_00423 1.3e-173 ydhF S Oxidoreductase
EEFEMGPG_00424 0.0 mtlR K transcriptional regulator, MtlR
EEFEMGPG_00425 6.5e-287 ydaB IQ acyl-CoA ligase
EEFEMGPG_00426 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_00427 1.7e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EEFEMGPG_00428 6.1e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EEFEMGPG_00429 1.4e-77 ydaG 1.4.3.5 S general stress protein
EEFEMGPG_00430 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EEFEMGPG_00431 4e-122 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_00432 1.2e-44 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_00433 1.3e-47 ydzA EGP Major facilitator Superfamily
EEFEMGPG_00434 5.6e-74 lrpC K Transcriptional regulator
EEFEMGPG_00435 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EEFEMGPG_00436 3.7e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EEFEMGPG_00437 1.9e-147 ydaK T Diguanylate cyclase, GGDEF domain
EEFEMGPG_00438 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EEFEMGPG_00439 7.2e-231 ydaM M Glycosyl transferase family group 2
EEFEMGPG_00440 0.0 ydaN S Bacterial cellulose synthase subunit
EEFEMGPG_00441 0.0 ydaO E amino acid
EEFEMGPG_00442 2.9e-54 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EEFEMGPG_00443 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EEFEMGPG_00444 3.6e-37 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EEFEMGPG_00445 4.1e-86 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EEFEMGPG_00446 4.4e-70
EEFEMGPG_00447 1.7e-207 S Histidine kinase
EEFEMGPG_00449 7.9e-11
EEFEMGPG_00451 2.8e-78
EEFEMGPG_00452 1.3e-99
EEFEMGPG_00453 2.1e-39
EEFEMGPG_00454 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
EEFEMGPG_00456 1.9e-33 ydaT
EEFEMGPG_00457 2.4e-71 yvaD S Family of unknown function (DUF5360)
EEFEMGPG_00458 7e-54 yvaE P Small Multidrug Resistance protein
EEFEMGPG_00459 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EEFEMGPG_00461 2.5e-40 ydbB G Cupin domain
EEFEMGPG_00462 8.5e-60 ydbC S Domain of unknown function (DUF4937
EEFEMGPG_00463 6.5e-156 ydbD P Catalase
EEFEMGPG_00464 7.1e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EEFEMGPG_00465 6.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EEFEMGPG_00466 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
EEFEMGPG_00467 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EEFEMGPG_00468 3.2e-160 ydbI S AI-2E family transporter
EEFEMGPG_00469 3.3e-172 ydbJ V ABC transporter, ATP-binding protein
EEFEMGPG_00470 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EEFEMGPG_00471 2.1e-52 ydbL
EEFEMGPG_00472 2.4e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EEFEMGPG_00473 8.6e-11 S Fur-regulated basic protein B
EEFEMGPG_00474 5.2e-08 S Fur-regulated basic protein A
EEFEMGPG_00475 1.2e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EEFEMGPG_00476 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EEFEMGPG_00477 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EEFEMGPG_00478 2.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EEFEMGPG_00479 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EEFEMGPG_00480 1.3e-60 ydbS S Bacterial PH domain
EEFEMGPG_00481 2.4e-262 ydbT S Membrane
EEFEMGPG_00482 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EEFEMGPG_00483 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EEFEMGPG_00484 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EEFEMGPG_00485 4.8e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EEFEMGPG_00486 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EEFEMGPG_00487 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EEFEMGPG_00488 6.1e-146 rsbR T Positive regulator of sigma-B
EEFEMGPG_00489 1.8e-57 rsbS T antagonist
EEFEMGPG_00490 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EEFEMGPG_00491 4.6e-188 rsbU 3.1.3.3 KT phosphatase
EEFEMGPG_00492 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
EEFEMGPG_00493 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EEFEMGPG_00494 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_00495 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EEFEMGPG_00496 0.0 yhgF K COG2183 Transcriptional accessory protein
EEFEMGPG_00497 1.7e-14
EEFEMGPG_00498 1.1e-58 ydcK S Belongs to the SprT family
EEFEMGPG_00506 2.8e-96 ywrO 1.6.5.2 S Flavodoxin-like fold
EEFEMGPG_00507 1.3e-72 S SnoaL-like polyketide cyclase
EEFEMGPG_00508 1.4e-141 yddR S Zn-dependent hydrolases of the beta-lactamase fold
EEFEMGPG_00509 1.3e-69 lrpA K transcriptional
EEFEMGPG_00510 2.9e-151 S Serine aminopeptidase, S33
EEFEMGPG_00511 8.8e-230 proP EGP Transporter
EEFEMGPG_00512 4.5e-49 ohrR K Transcriptional regulator
EEFEMGPG_00513 1.6e-85 S Domain of unknown function with cystatin-like fold (DUF4467)
EEFEMGPG_00514 3.9e-72 maoC I N-terminal half of MaoC dehydratase
EEFEMGPG_00515 1.6e-63 yyaQ S YjbR
EEFEMGPG_00516 3.3e-74 ywnA K Transcriptional regulator
EEFEMGPG_00517 6.4e-111 ywnB S NAD(P)H-binding
EEFEMGPG_00518 1.8e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EEFEMGPG_00519 5.2e-30 cspL K Cold shock
EEFEMGPG_00520 2.7e-79 carD K Transcription factor
EEFEMGPG_00521 1.6e-120 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EEFEMGPG_00522 9.5e-90 S Protein of unknown function (DUF2812)
EEFEMGPG_00523 9.8e-52 K Transcriptional regulator PadR-like family
EEFEMGPG_00524 8e-182 S Patatin-like phospholipase
EEFEMGPG_00525 9.4e-83 S DinB superfamily
EEFEMGPG_00526 1.5e-49 G Cupin domain
EEFEMGPG_00529 4.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
EEFEMGPG_00530 9.7e-148 czcD P COG1230 Co Zn Cd efflux system component
EEFEMGPG_00531 1e-198 trkA P Oxidoreductase
EEFEMGPG_00533 4.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
EEFEMGPG_00535 7.9e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EEFEMGPG_00536 3.5e-56 ydeH
EEFEMGPG_00537 6.4e-84 F nucleoside 2-deoxyribosyltransferase
EEFEMGPG_00538 4.3e-194 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EEFEMGPG_00539 2.3e-147 Q ubiE/COQ5 methyltransferase family
EEFEMGPG_00540 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EEFEMGPG_00541 4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EEFEMGPG_00542 4e-165 S Sodium Bile acid symporter family
EEFEMGPG_00543 2.2e-137 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_00544 2.7e-44 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_00545 1.3e-201 adhA 1.1.1.1 C alcohol dehydrogenase
EEFEMGPG_00546 3.6e-67 yraB K helix_turn_helix, mercury resistance
EEFEMGPG_00547 6.7e-224 mleN_2 C antiporter
EEFEMGPG_00548 4.7e-260 K helix_turn_helix gluconate operon transcriptional repressor
EEFEMGPG_00549 1.6e-114 paiB K Transcriptional regulator
EEFEMGPG_00551 4.3e-177 ydeR EGP Major facilitator Superfamily
EEFEMGPG_00552 1.3e-102 ydeS K Transcriptional regulator
EEFEMGPG_00553 3.7e-157 ydeK EG -transporter
EEFEMGPG_00554 7.1e-264 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EEFEMGPG_00555 9.5e-49 yraD M Spore coat protein
EEFEMGPG_00556 4.1e-24 yraE
EEFEMGPG_00557 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EEFEMGPG_00558 8.4e-63 yraF M Spore coat protein
EEFEMGPG_00559 1.2e-36 yraG
EEFEMGPG_00560 1.3e-219 ydfH 2.7.13.3 T Histidine kinase
EEFEMGPG_00561 8.3e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_00562 0.0 ydfJ S drug exporters of the RND superfamily
EEFEMGPG_00563 7.2e-135 puuD S Peptidase C26
EEFEMGPG_00564 6.7e-298 expZ S ABC transporter
EEFEMGPG_00565 2.1e-99 ynaD J Acetyltransferase (GNAT) domain
EEFEMGPG_00566 7.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_00567 1.1e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EEFEMGPG_00568 2.3e-210 tcaB EGP Major facilitator Superfamily
EEFEMGPG_00569 1.3e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EEFEMGPG_00570 1.3e-156 K Helix-turn-helix XRE-family like proteins
EEFEMGPG_00571 1.3e-123 ydhB S membrane transporter protein
EEFEMGPG_00572 4.5e-82 bltD 2.3.1.57 K FR47-like protein
EEFEMGPG_00573 1.2e-11 bltR K helix_turn_helix, mercury resistance
EEFEMGPG_00574 6e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EEFEMGPG_00575 2.6e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
EEFEMGPG_00576 2.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
EEFEMGPG_00577 5.8e-118 ydhC K FCD
EEFEMGPG_00578 4.1e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EEFEMGPG_00581 2.2e-265 pbpE V Beta-lactamase
EEFEMGPG_00583 2.5e-98 ydhK M Protein of unknown function (DUF1541)
EEFEMGPG_00584 1.2e-195 pbuE EGP Major facilitator Superfamily
EEFEMGPG_00585 4.3e-132 ydhQ K UTRA
EEFEMGPG_00586 1.3e-117 K FCD
EEFEMGPG_00587 2.2e-216 yeaN P COG2807 Cyanate permease
EEFEMGPG_00588 2.6e-49 sugE P Small Multidrug Resistance protein
EEFEMGPG_00589 2.3e-51 ykkC P Small Multidrug Resistance protein
EEFEMGPG_00590 5.3e-104 yvdT K Transcriptional regulator
EEFEMGPG_00591 2.1e-296 yveA E amino acid
EEFEMGPG_00592 3.5e-165 ydhU P Catalase
EEFEMGPG_00593 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EEFEMGPG_00594 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
EEFEMGPG_00595 6.3e-252 iolT EGP Major facilitator Superfamily
EEFEMGPG_00598 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00599 7.8e-08
EEFEMGPG_00601 3.3e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EEFEMGPG_00602 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EEFEMGPG_00603 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EEFEMGPG_00604 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EEFEMGPG_00605 2.3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EEFEMGPG_00606 0.0 ydiF S ABC transporter
EEFEMGPG_00607 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EEFEMGPG_00608 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EEFEMGPG_00609 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EEFEMGPG_00610 1.4e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EEFEMGPG_00611 1.7e-27 ydiK S Domain of unknown function (DUF4305)
EEFEMGPG_00612 1.3e-126 ydiL S CAAX protease self-immunity
EEFEMGPG_00613 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EEFEMGPG_00614 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EEFEMGPG_00615 4e-77 S Phage integrase family
EEFEMGPG_00616 5.4e-30 yqaB E IrrE N-terminal-like domain
EEFEMGPG_00617 3.2e-37 S Domain of unknown function (DUF4352)
EEFEMGPG_00618 3.3e-14 K transcriptional regulator
EEFEMGPG_00619 9.8e-11 K Helix-turn-helix XRE-family like proteins
EEFEMGPG_00620 1.2e-19
EEFEMGPG_00621 8.2e-46 S Phage regulatory protein Rha (Phage_pRha)
EEFEMGPG_00622 4.2e-85
EEFEMGPG_00626 6.9e-98
EEFEMGPG_00627 1.1e-64 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EEFEMGPG_00629 4.1e-29 3.1.3.16 L DnaD domain protein
EEFEMGPG_00630 2.7e-121 xkdC L IstB-like ATP binding protein
EEFEMGPG_00632 2.4e-35 S YopX protein
EEFEMGPG_00633 2.6e-53 S Protein of unknown function (DUF1064)
EEFEMGPG_00635 5e-17 yqaO S Phage-like element PBSX protein XtrA
EEFEMGPG_00638 6.4e-24
EEFEMGPG_00640 1.7e-90 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
EEFEMGPG_00643 8.3e-53 S dUTPase
EEFEMGPG_00644 3.8e-11 S YopX protein
EEFEMGPG_00647 1.1e-45
EEFEMGPG_00651 1.4e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EEFEMGPG_00653 1.7e-12 K Transcriptional regulator
EEFEMGPG_00655 1.2e-16 K Transcriptional regulator
EEFEMGPG_00657 5.8e-47 L Terminase small subunit
EEFEMGPG_00658 1.2e-196 S Phage terminase large subunit
EEFEMGPG_00660 2.1e-125 S Phage portal protein, SPP1 Gp6-like
EEFEMGPG_00661 6.2e-91 S Phage Mu protein F like protein
EEFEMGPG_00662 9.7e-43 S Phage minor structural protein GP20
EEFEMGPG_00664 7.2e-114 gpG
EEFEMGPG_00666 7.8e-27 S Phage gp6-like head-tail connector protein
EEFEMGPG_00667 1.4e-27 S Phage head-tail joining protein
EEFEMGPG_00668 6.3e-37 S Bacteriophage HK97-gp10, putative tail-component
EEFEMGPG_00669 3.5e-30 S Protein of unknown function (DUF3168)
EEFEMGPG_00670 4.3e-33 S Phage tail tube protein
EEFEMGPG_00671 4.3e-25 S Phage tail assembly chaperone protein, TAC
EEFEMGPG_00673 2.7e-130
EEFEMGPG_00674 6e-47
EEFEMGPG_00675 1.6e-224 S peptidoglycan catabolic process
EEFEMGPG_00680 2.4e-30 xhlA S Haemolysin XhlA
EEFEMGPG_00681 2.4e-27 xhlB S SPP1 phage holin
EEFEMGPG_00682 6.7e-74 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EEFEMGPG_00683 2e-16
EEFEMGPG_00684 2.7e-40
EEFEMGPG_00685 1e-50 V Abortive infection bacteriophage resistance protein
EEFEMGPG_00686 3.6e-17
EEFEMGPG_00687 3.4e-92 T LytTr DNA-binding domain
EEFEMGPG_00689 1.5e-56 KOT accessory gene regulator B
EEFEMGPG_00690 4.4e-58 2.7.13.3 T protein histidine kinase activity
EEFEMGPG_00692 1.9e-208 lcnDR2 V Lanthionine synthetase C-like protein
EEFEMGPG_00695 9.8e-149 lanM V Lanthionine synthetase C-like protein
EEFEMGPG_00696 2.2e-216 3.6.3.27 V Peptidase C39 family
EEFEMGPG_00697 2.2e-32
EEFEMGPG_00698 1.5e-137 bcrA V ABC transporter, ATP-binding protein
EEFEMGPG_00699 3.8e-96 bcrB1 S ABC-2 family transporter protein
EEFEMGPG_00700 1.8e-109 mrsE1 S ABC-2 family transporter protein
EEFEMGPG_00701 4.3e-25 K Helix-turn-helix XRE-family like proteins
EEFEMGPG_00702 6.8e-114 V ABC transporter, ATP-binding protein
EEFEMGPG_00703 7.5e-68 S ABC-2 family transporter protein
EEFEMGPG_00704 6.3e-89 S ABC-2 family transporter protein
EEFEMGPG_00705 4.7e-175 O COG1404 Subtilisin-like serine proteases
EEFEMGPG_00706 0.0 K NB-ARC domain
EEFEMGPG_00707 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
EEFEMGPG_00708 9.8e-250 gutA G MFS/sugar transport protein
EEFEMGPG_00709 8.3e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EEFEMGPG_00710 2.8e-30 yjdJ S Domain of unknown function (DUF4306)
EEFEMGPG_00711 3.9e-114 pspA KT Phage shock protein A
EEFEMGPG_00712 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EEFEMGPG_00713 1e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EEFEMGPG_00714 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
EEFEMGPG_00715 0.0 yrhL I Acyltransferase family
EEFEMGPG_00716 2.3e-143 rsiV S Protein of unknown function (DUF3298)
EEFEMGPG_00717 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_00718 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EEFEMGPG_00719 4.2e-62 ydjM M Lytic transglycolase
EEFEMGPG_00720 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
EEFEMGPG_00722 8.6e-35 ydjO S Cold-inducible protein YdjO
EEFEMGPG_00723 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EEFEMGPG_00724 1.6e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_00725 2.2e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EEFEMGPG_00726 1.3e-176 yeaC S COG0714 MoxR-like ATPases
EEFEMGPG_00727 2e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EEFEMGPG_00728 0.0 yebA E COG1305 Transglutaminase-like enzymes
EEFEMGPG_00729 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EEFEMGPG_00730 5.9e-127 K Acetyltransferase (GNAT) domain
EEFEMGPG_00731 6.6e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_00732 7.4e-248 S Domain of unknown function (DUF4179)
EEFEMGPG_00733 1.1e-208 pbuG S permease
EEFEMGPG_00734 1.9e-133 yebC M Membrane
EEFEMGPG_00736 8.9e-93 yebE S UPF0316 protein
EEFEMGPG_00737 6.1e-28 yebG S NETI protein
EEFEMGPG_00738 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EEFEMGPG_00739 6.1e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EEFEMGPG_00740 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EEFEMGPG_00741 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EEFEMGPG_00742 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEFEMGPG_00743 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEFEMGPG_00744 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEFEMGPG_00745 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EEFEMGPG_00746 2.7e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EEFEMGPG_00747 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EEFEMGPG_00748 7.8e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EEFEMGPG_00749 3.7e-235 purD 6.3.4.13 F Belongs to the GARS family
EEFEMGPG_00750 1.2e-25 S Protein of unknown function (DUF2892)
EEFEMGPG_00751 0.0 yerA 3.5.4.2 F adenine deaminase
EEFEMGPG_00752 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
EEFEMGPG_00753 2.4e-50 yerC S protein conserved in bacteria
EEFEMGPG_00754 3e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EEFEMGPG_00755 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EEFEMGPG_00756 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EEFEMGPG_00757 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EEFEMGPG_00758 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
EEFEMGPG_00759 1.5e-194 yerI S homoserine kinase type II (protein kinase fold)
EEFEMGPG_00760 1.3e-120 sapB S MgtC SapB transporter
EEFEMGPG_00761 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEFEMGPG_00762 4.8e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EEFEMGPG_00763 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EEFEMGPG_00764 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EEFEMGPG_00765 4.8e-154 yerO K Transcriptional regulator
EEFEMGPG_00766 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEFEMGPG_00767 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EEFEMGPG_00768 2.7e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EEFEMGPG_00769 6.1e-112 S Protein of unknown function DUF262
EEFEMGPG_00770 1.2e-46
EEFEMGPG_00771 9.9e-135 2.1.1.113 L DNA methylase
EEFEMGPG_00772 3.4e-61 S Protein of unknown function, DUF600
EEFEMGPG_00773 4.5e-92 yobL L nucleic acid phosphodiester bond hydrolysis
EEFEMGPG_00774 3.9e-42 S Immunity protein 22
EEFEMGPG_00776 4.5e-74 S Protein of unknown function, DUF600
EEFEMGPG_00777 1.1e-57 S Protein of unknown function, DUF600
EEFEMGPG_00778 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
EEFEMGPG_00779 9.4e-127 yeeN K transcriptional regulatory protein
EEFEMGPG_00781 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
EEFEMGPG_00782 3.3e-45 cotJB S CotJB protein
EEFEMGPG_00783 8.9e-104 cotJC P Spore Coat
EEFEMGPG_00784 4e-98 yesJ K Acetyltransferase (GNAT) family
EEFEMGPG_00786 1.3e-120 yetF S membrane
EEFEMGPG_00787 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EEFEMGPG_00788 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EEFEMGPG_00789 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EEFEMGPG_00790 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
EEFEMGPG_00791 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
EEFEMGPG_00792 1.8e-105 yetJ S Belongs to the BI1 family
EEFEMGPG_00793 6.5e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_00794 1.4e-206 yetM CH FAD binding domain
EEFEMGPG_00795 7.5e-197 yetN S Protein of unknown function (DUF3900)
EEFEMGPG_00796 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EEFEMGPG_00798 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
EEFEMGPG_00799 2e-166 V ATPases associated with a variety of cellular activities
EEFEMGPG_00800 1.7e-126 V ABC-2 type transporter
EEFEMGPG_00803 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EEFEMGPG_00804 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
EEFEMGPG_00805 2.4e-172 yfnG 4.2.1.45 M dehydratase
EEFEMGPG_00806 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
EEFEMGPG_00807 1.2e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EEFEMGPG_00808 2.1e-187 yfnD M Nucleotide-diphospho-sugar transferase
EEFEMGPG_00809 8e-219 fsr P COG0477 Permeases of the major facilitator superfamily
EEFEMGPG_00810 2.3e-246 yfnA E amino acid
EEFEMGPG_00811 7.7e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EEFEMGPG_00812 9.8e-115 yfmS NT chemotaxis protein
EEFEMGPG_00813 9.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
EEFEMGPG_00814 2.1e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EEFEMGPG_00815 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EEFEMGPG_00816 4.4e-68 yfmP K transcriptional
EEFEMGPG_00817 5.2e-207 yfmO EGP Major facilitator Superfamily
EEFEMGPG_00818 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EEFEMGPG_00819 3.2e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EEFEMGPG_00820 1.7e-65 yfmK 2.3.1.128 K acetyltransferase
EEFEMGPG_00821 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
EEFEMGPG_00822 7.7e-24 S Protein of unknown function (DUF3212)
EEFEMGPG_00823 1.3e-57 yflT S Heat induced stress protein YflT
EEFEMGPG_00824 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EEFEMGPG_00825 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
EEFEMGPG_00826 1e-28 Q PFAM Collagen triple helix
EEFEMGPG_00830 1.6e-22 M1-820 Q Collagen triple helix repeat (20 copies)
EEFEMGPG_00831 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
EEFEMGPG_00832 0.0 ywpD T PhoQ Sensor
EEFEMGPG_00833 8.7e-153 M1-574 T Transcriptional regulatory protein, C terminal
EEFEMGPG_00834 0.0 M1-568 M cell wall anchor domain
EEFEMGPG_00835 2.7e-80 srtA 3.4.22.70 M Sortase family
EEFEMGPG_00836 2.7e-275 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EEFEMGPG_00837 4.4e-118 citT T response regulator
EEFEMGPG_00838 4.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
EEFEMGPG_00839 1.1e-226 citM C Citrate transporter
EEFEMGPG_00840 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EEFEMGPG_00841 5.5e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EEFEMGPG_00842 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EEFEMGPG_00843 4.4e-123 yflK S protein conserved in bacteria
EEFEMGPG_00844 1.5e-14 yflJ S Protein of unknown function (DUF2639)
EEFEMGPG_00845 7e-19 yflI
EEFEMGPG_00846 9e-50 yflH S Protein of unknown function (DUF3243)
EEFEMGPG_00847 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
EEFEMGPG_00848 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EEFEMGPG_00849 1.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
EEFEMGPG_00850 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EEFEMGPG_00851 2.3e-63 yhdN S Domain of unknown function (DUF1992)
EEFEMGPG_00852 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
EEFEMGPG_00853 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
EEFEMGPG_00854 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
EEFEMGPG_00855 8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_00856 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EEFEMGPG_00857 1.7e-128 treR K transcriptional
EEFEMGPG_00858 1.2e-123 yfkO C nitroreductase
EEFEMGPG_00859 2.7e-124 yibF S YibE/F-like protein
EEFEMGPG_00860 1.1e-201 yibE S YibE/F-like protein
EEFEMGPG_00862 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EEFEMGPG_00863 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
EEFEMGPG_00864 1.5e-186 K helix_turn _helix lactose operon repressor
EEFEMGPG_00865 3.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EEFEMGPG_00866 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EEFEMGPG_00867 2.1e-192 ydiM EGP Major facilitator Superfamily
EEFEMGPG_00868 2.7e-29 yfkK S Belongs to the UPF0435 family
EEFEMGPG_00869 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EEFEMGPG_00870 8.5e-51 yfkI S gas vesicle protein
EEFEMGPG_00871 6.8e-145 yihY S Belongs to the UPF0761 family
EEFEMGPG_00872 2.5e-07
EEFEMGPG_00873 5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EEFEMGPG_00874 1.3e-185 cax P COG0387 Ca2 H antiporter
EEFEMGPG_00875 1.9e-144 yfkD S YfkD-like protein
EEFEMGPG_00876 4.3e-147 yfkC M Mechanosensitive ion channel
EEFEMGPG_00877 6.6e-220 yfkA S YfkB-like domain
EEFEMGPG_00878 4.9e-27 yfjT
EEFEMGPG_00879 2e-154 pdaA G deacetylase
EEFEMGPG_00880 2.9e-151 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EEFEMGPG_00881 3.9e-31
EEFEMGPG_00882 1.7e-184 corA P Mediates influx of magnesium ions
EEFEMGPG_00883 7.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EEFEMGPG_00884 2.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EEFEMGPG_00885 1.5e-49 S YfzA-like protein
EEFEMGPG_00887 7.9e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEFEMGPG_00888 3.3e-94 yfjM S Psort location Cytoplasmic, score
EEFEMGPG_00889 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EEFEMGPG_00890 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EEFEMGPG_00891 2.3e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EEFEMGPG_00892 4.1e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EEFEMGPG_00893 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EEFEMGPG_00894 4.2e-15 sspH S Belongs to the SspH family
EEFEMGPG_00895 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EEFEMGPG_00896 2.5e-138 glvR F Helix-turn-helix domain, rpiR family
EEFEMGPG_00897 5.2e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_00898 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
EEFEMGPG_00899 0.0 yfiB3 V ABC transporter
EEFEMGPG_00900 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EEFEMGPG_00901 7e-63 mhqP S DoxX
EEFEMGPG_00902 7.7e-160 yfiE 1.13.11.2 S glyoxalase
EEFEMGPG_00903 4.1e-98 K AraC-like ligand binding domain
EEFEMGPG_00904 4.8e-192 iolT EGP Major facilitator Superfamily
EEFEMGPG_00905 2.3e-157 G Xylose isomerase
EEFEMGPG_00906 4.2e-193 S Oxidoreductase
EEFEMGPG_00907 3.8e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EEFEMGPG_00908 4.3e-95 padR K transcriptional
EEFEMGPG_00909 2.7e-111 1.6.5.2 S NADPH-dependent FMN reductase
EEFEMGPG_00910 7.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EEFEMGPG_00911 1.8e-19 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EEFEMGPG_00912 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
EEFEMGPG_00913 1.5e-45 yrdF K ribonuclease inhibitor
EEFEMGPG_00914 9.6e-100 yfiT S Belongs to the metal hydrolase YfiT family
EEFEMGPG_00915 1.4e-287 yfiU EGP Major facilitator Superfamily
EEFEMGPG_00916 5.6e-83 yfiV K transcriptional
EEFEMGPG_00917 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EEFEMGPG_00918 2.3e-167 yfhB 5.3.3.17 S PhzF family
EEFEMGPG_00919 3.3e-106 yfhC C nitroreductase
EEFEMGPG_00920 2.1e-25 yfhD S YfhD-like protein
EEFEMGPG_00922 1.5e-166 yfhF S nucleoside-diphosphate sugar epimerase
EEFEMGPG_00923 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
EEFEMGPG_00924 8.8e-53 yfhH S Protein of unknown function (DUF1811)
EEFEMGPG_00925 2.6e-206 yfhI EGP Major facilitator Superfamily
EEFEMGPG_00927 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EEFEMGPG_00928 2.2e-44 yfhJ S WVELL protein
EEFEMGPG_00929 7.7e-94 batE T Bacterial SH3 domain homologues
EEFEMGPG_00930 2.6e-34 yfhL S SdpI/YhfL protein family
EEFEMGPG_00931 4.4e-171 yfhM S Alpha/beta hydrolase family
EEFEMGPG_00932 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EEFEMGPG_00933 0.0 yfhO S Bacterial membrane protein YfhO
EEFEMGPG_00934 1e-184 yfhP S membrane-bound metal-dependent
EEFEMGPG_00935 2.7e-210 mutY L A G-specific
EEFEMGPG_00936 8.2e-37 yfhS
EEFEMGPG_00937 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_00939 1.5e-37 ygaB S YgaB-like protein
EEFEMGPG_00940 2.2e-104 ygaC J Belongs to the UPF0374 family
EEFEMGPG_00941 2.1e-305 ygaD V ABC transporter
EEFEMGPG_00942 2.1e-178 ygaE S Membrane
EEFEMGPG_00943 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EEFEMGPG_00944 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
EEFEMGPG_00945 1.8e-80 perR P Belongs to the Fur family
EEFEMGPG_00946 1.5e-56 ygzB S UPF0295 protein
EEFEMGPG_00947 8.2e-165 ygxA S Nucleotidyltransferase-like
EEFEMGPG_00948 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_00953 7.8e-08
EEFEMGPG_00961 1.6e-08
EEFEMGPG_00965 1.5e-286 C Na+/H+ antiporter family
EEFEMGPG_00966 3.2e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EEFEMGPG_00967 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EEFEMGPG_00968 3.7e-265 ygaK C Berberine and berberine like
EEFEMGPG_00970 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
EEFEMGPG_00971 1.7e-136 appB P Binding-protein-dependent transport system inner membrane component
EEFEMGPG_00972 1.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_00973 8.3e-134 oppD3 P Belongs to the ABC transporter superfamily
EEFEMGPG_00974 6.2e-134 oppF3 E Belongs to the ABC transporter superfamily
EEFEMGPG_00975 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EEFEMGPG_00976 7.5e-185 S Amidohydrolase
EEFEMGPG_00977 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EEFEMGPG_00978 1.6e-180 ssuA M Sulfonate ABC transporter
EEFEMGPG_00979 2.6e-144 ssuC P ABC transporter (permease)
EEFEMGPG_00980 1.1e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EEFEMGPG_00981 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EEFEMGPG_00982 3e-81 ygaO
EEFEMGPG_00983 4.8e-23 K Transcriptional regulator
EEFEMGPG_00985 1.1e-112 yhzB S B3/4 domain
EEFEMGPG_00986 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EEFEMGPG_00987 4.8e-176 yhbB S Putative amidase domain
EEFEMGPG_00988 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EEFEMGPG_00989 1e-108 yhbD K Protein of unknown function (DUF4004)
EEFEMGPG_00990 9.5e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EEFEMGPG_00991 2.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EEFEMGPG_00993 0.0 prkA T Ser protein kinase
EEFEMGPG_00994 2.7e-216 yhbH S Belongs to the UPF0229 family
EEFEMGPG_00995 4.6e-74 yhbI K DNA-binding transcription factor activity
EEFEMGPG_00996 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
EEFEMGPG_00997 8.4e-285 yhcA EGP Major facilitator Superfamily
EEFEMGPG_00998 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
EEFEMGPG_00999 3.8e-55 yhcC
EEFEMGPG_01000 6.2e-52
EEFEMGPG_01001 3e-60 yhcF K Transcriptional regulator
EEFEMGPG_01002 1e-125 yhcG V ABC transporter, ATP-binding protein
EEFEMGPG_01003 1.5e-166 yhcH V ABC transporter, ATP-binding protein
EEFEMGPG_01004 1.1e-162 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EEFEMGPG_01005 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
EEFEMGPG_01006 2.9e-148 metQ M Belongs to the nlpA lipoprotein family
EEFEMGPG_01007 5.4e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EEFEMGPG_01008 7.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EEFEMGPG_01009 1.6e-55 yhcM
EEFEMGPG_01010 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EEFEMGPG_01011 1.8e-159 yhcP
EEFEMGPG_01012 2.9e-114 yhcQ M Spore coat protein
EEFEMGPG_01013 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
EEFEMGPG_01014 1.6e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EEFEMGPG_01015 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EEFEMGPG_01016 1.1e-68 yhcU S Family of unknown function (DUF5365)
EEFEMGPG_01017 2.6e-68 yhcV S COG0517 FOG CBS domain
EEFEMGPG_01018 4.9e-125 yhcW 5.4.2.6 S hydrolase
EEFEMGPG_01019 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EEFEMGPG_01020 2.7e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEFEMGPG_01021 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EEFEMGPG_01022 1.7e-148 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EEFEMGPG_01023 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EEFEMGPG_01024 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EEFEMGPG_01025 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EEFEMGPG_01026 1.9e-203 yhcY 2.7.13.3 T Histidine kinase
EEFEMGPG_01027 2.9e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_01028 1.5e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
EEFEMGPG_01029 2.5e-39 yhdB S YhdB-like protein
EEFEMGPG_01030 4e-53 yhdC S Protein of unknown function (DUF3889)
EEFEMGPG_01031 9.8e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EEFEMGPG_01032 5.6e-74 nsrR K Transcriptional regulator
EEFEMGPG_01033 5e-255 ygxB M Conserved TM helix
EEFEMGPG_01034 1.2e-271 ycgB S Stage V sporulation protein R
EEFEMGPG_01035 1.2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EEFEMGPG_01036 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EEFEMGPG_01037 1.5e-163 citR K Transcriptional regulator
EEFEMGPG_01038 1.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
EEFEMGPG_01039 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_01040 4.1e-251 yhdG E amino acid
EEFEMGPG_01041 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EEFEMGPG_01042 8.1e-45 yhdK S Sigma-M inhibitor protein
EEFEMGPG_01043 1.3e-201 yhdL S Sigma factor regulator N-terminal
EEFEMGPG_01044 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_01045 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EEFEMGPG_01046 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EEFEMGPG_01047 4.3e-71 cueR K transcriptional
EEFEMGPG_01048 1.2e-224 yhdR 2.6.1.1 E Aminotransferase
EEFEMGPG_01049 6.6e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EEFEMGPG_01050 9.3e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EEFEMGPG_01051 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EEFEMGPG_01052 5.5e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EEFEMGPG_01053 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EEFEMGPG_01055 1.6e-205 yhdY M Mechanosensitive ion channel
EEFEMGPG_01056 2.2e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EEFEMGPG_01057 1.2e-157 yheN G deacetylase
EEFEMGPG_01058 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EEFEMGPG_01059 4.6e-88 pksA K Transcriptional regulator
EEFEMGPG_01060 2.3e-93 ymcC S Membrane
EEFEMGPG_01061 1.8e-84 T universal stress protein
EEFEMGPG_01063 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EEFEMGPG_01064 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EEFEMGPG_01065 4e-110 yheG GM NAD(P)H-binding
EEFEMGPG_01067 2.9e-28 sspB S spore protein
EEFEMGPG_01068 1.7e-36 yheE S Family of unknown function (DUF5342)
EEFEMGPG_01069 1.6e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EEFEMGPG_01070 6.9e-214 yheC HJ YheC/D like ATP-grasp
EEFEMGPG_01071 7.2e-206 yheB S Belongs to the UPF0754 family
EEFEMGPG_01072 4.4e-53 yheA S Belongs to the UPF0342 family
EEFEMGPG_01073 3e-196 yhaZ L DNA alkylation repair enzyme
EEFEMGPG_01074 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
EEFEMGPG_01075 9.3e-294 hemZ H coproporphyrinogen III oxidase
EEFEMGPG_01076 5.1e-248 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
EEFEMGPG_01077 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
EEFEMGPG_01078 3e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EEFEMGPG_01080 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
EEFEMGPG_01081 7.3e-15 S YhzD-like protein
EEFEMGPG_01082 6.8e-167 yhaQ S ABC transporter, ATP-binding protein
EEFEMGPG_01083 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EEFEMGPG_01084 3.2e-236 yhaO L DNA repair exonuclease
EEFEMGPG_01085 0.0 yhaN L AAA domain
EEFEMGPG_01086 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
EEFEMGPG_01087 3.1e-31 yhaL S Sporulation protein YhaL
EEFEMGPG_01088 3.4e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EEFEMGPG_01089 7e-95 yhaK S Putative zincin peptidase
EEFEMGPG_01090 9.9e-55 yhaI S Protein of unknown function (DUF1878)
EEFEMGPG_01091 8.6e-113 hpr K Negative regulator of protease production and sporulation
EEFEMGPG_01092 6.2e-39 yhaH S YtxH-like protein
EEFEMGPG_01093 2e-17
EEFEMGPG_01094 3.8e-77 trpP S Tryptophan transporter TrpP
EEFEMGPG_01095 1.6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EEFEMGPG_01096 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EEFEMGPG_01097 1.1e-135 ecsA V transporter (ATP-binding protein)
EEFEMGPG_01098 8.5e-221 ecsB U ABC transporter
EEFEMGPG_01099 2.1e-123 ecsC S EcsC protein family
EEFEMGPG_01100 3.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EEFEMGPG_01101 3.1e-243 yhfA C membrane
EEFEMGPG_01102 9.2e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EEFEMGPG_01103 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EEFEMGPG_01104 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EEFEMGPG_01105 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EEFEMGPG_01106 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EEFEMGPG_01107 3.2e-101 yhgD K Transcriptional regulator
EEFEMGPG_01108 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
EEFEMGPG_01109 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEFEMGPG_01111 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EEFEMGPG_01112 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EEFEMGPG_01113 7.9e-11 yhfH S YhfH-like protein
EEFEMGPG_01114 4.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EEFEMGPG_01115 1.3e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
EEFEMGPG_01116 1e-111 yhfK GM NmrA-like family
EEFEMGPG_01117 6.2e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EEFEMGPG_01118 8.7e-66 yhfM
EEFEMGPG_01119 6e-238 yhfN 3.4.24.84 O Peptidase M48
EEFEMGPG_01120 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EEFEMGPG_01121 2e-155 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EEFEMGPG_01122 3.1e-104 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EEFEMGPG_01123 4.6e-202 vraB 2.3.1.9 I Belongs to the thiolase family
EEFEMGPG_01124 9.5e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EEFEMGPG_01125 9.3e-90 bioY S BioY family
EEFEMGPG_01126 3.1e-197 hemAT NT chemotaxis protein
EEFEMGPG_01127 5.3e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EEFEMGPG_01128 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_01129 1.8e-31 yhzC S IDEAL
EEFEMGPG_01130 1.9e-109 comK K Competence transcription factor
EEFEMGPG_01131 8.6e-68 frataxin S Domain of unknown function (DU1801)
EEFEMGPG_01132 6.2e-66 frataxin S Domain of unknown function (DU1801)
EEFEMGPG_01133 5.5e-49 mepB S MepB protein
EEFEMGPG_01134 3.3e-124 yrpD S Domain of unknown function, YrpD
EEFEMGPG_01135 1.6e-42 yhjA S Excalibur calcium-binding domain
EEFEMGPG_01136 3.3e-47 S Belongs to the UPF0145 family
EEFEMGPG_01137 1.9e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEFEMGPG_01138 1.4e-27 yhjC S Protein of unknown function (DUF3311)
EEFEMGPG_01139 1.7e-60 yhjD
EEFEMGPG_01140 2.6e-109 yhjE S SNARE associated Golgi protein
EEFEMGPG_01141 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EEFEMGPG_01142 8.6e-276 yhjG CH FAD binding domain
EEFEMGPG_01143 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_01144 4.3e-182 abrB S membrane
EEFEMGPG_01145 2.5e-209 blt EGP Major facilitator Superfamily
EEFEMGPG_01146 1e-108 K QacR-like protein, C-terminal region
EEFEMGPG_01147 4.8e-93 yhjR S Rubrerythrin
EEFEMGPG_01148 2.2e-120 ydfS S Protein of unknown function (DUF421)
EEFEMGPG_01149 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EEFEMGPG_01150 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EEFEMGPG_01151 1.9e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EEFEMGPG_01152 0.0 sbcC L COG0419 ATPase involved in DNA repair
EEFEMGPG_01153 2.9e-50 yisB V COG1403 Restriction endonuclease
EEFEMGPG_01154 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
EEFEMGPG_01155 8.1e-64 gerPE S Spore germination protein GerPE
EEFEMGPG_01156 3.1e-23 gerPD S Spore germination protein
EEFEMGPG_01157 4.1e-62 gerPC S Spore germination protein
EEFEMGPG_01158 6.2e-35 gerPB S cell differentiation
EEFEMGPG_01159 8.4e-34 gerPA S Spore germination protein
EEFEMGPG_01160 5e-07 yisI S Spo0E like sporulation regulatory protein
EEFEMGPG_01161 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EEFEMGPG_01162 1.1e-59 yisL S UPF0344 protein
EEFEMGPG_01163 3.1e-98 yisN S Protein of unknown function (DUF2777)
EEFEMGPG_01164 0.0 asnO 6.3.5.4 E Asparagine synthase
EEFEMGPG_01165 1.3e-134 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EEFEMGPG_01166 4.2e-245 yisQ V Mate efflux family protein
EEFEMGPG_01167 5e-159 yisR K Transcriptional regulator
EEFEMGPG_01168 3.7e-90 yisT S DinB family
EEFEMGPG_01169 1.3e-71 mcbG S Pentapeptide repeats (9 copies)
EEFEMGPG_01170 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
EEFEMGPG_01171 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EEFEMGPG_01172 6.6e-55 yajQ S Belongs to the UPF0234 family
EEFEMGPG_01173 1.8e-161 cvfB S protein conserved in bacteria
EEFEMGPG_01174 6.3e-174 yufN S ABC transporter substrate-binding protein PnrA-like
EEFEMGPG_01175 3.4e-233 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EEFEMGPG_01176 6.4e-240 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
EEFEMGPG_01178 3.2e-158 yitS S protein conserved in bacteria
EEFEMGPG_01179 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_01180 2.9e-81 ipi S Intracellular proteinase inhibitor
EEFEMGPG_01181 4.4e-26 S Protein of unknown function (DUF3813)
EEFEMGPG_01182 3.5e-07
EEFEMGPG_01183 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EEFEMGPG_01184 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EEFEMGPG_01185 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EEFEMGPG_01186 5.3e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EEFEMGPG_01187 6.6e-273 yitY C D-arabinono-1,4-lactone oxidase
EEFEMGPG_01188 4.1e-90 norB G Major Facilitator Superfamily
EEFEMGPG_01189 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EEFEMGPG_01190 7.9e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EEFEMGPG_01191 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EEFEMGPG_01192 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EEFEMGPG_01193 8.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EEFEMGPG_01194 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EEFEMGPG_01195 5.4e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EEFEMGPG_01196 1.2e-27 yjzC S YjzC-like protein
EEFEMGPG_01197 3.3e-23 yjzD S Protein of unknown function (DUF2929)
EEFEMGPG_01198 5.1e-136 yjaU I carboxylic ester hydrolase activity
EEFEMGPG_01199 8.8e-104 yjaV
EEFEMGPG_01200 1.9e-166 med S Transcriptional activator protein med
EEFEMGPG_01201 1.1e-26 comZ S ComZ
EEFEMGPG_01202 5.9e-32 yjzB
EEFEMGPG_01203 2.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEFEMGPG_01204 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EEFEMGPG_01205 1.6e-148 yjaZ O Zn-dependent protease
EEFEMGPG_01206 6.3e-182 appD P Belongs to the ABC transporter superfamily
EEFEMGPG_01207 5.9e-188 appF E Belongs to the ABC transporter superfamily
EEFEMGPG_01208 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EEFEMGPG_01209 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01210 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01211 5.5e-146 yjbA S Belongs to the UPF0736 family
EEFEMGPG_01212 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EEFEMGPG_01213 0.0 oppA E ABC transporter substrate-binding protein
EEFEMGPG_01214 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01215 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01216 2.7e-202 oppD P Belongs to the ABC transporter superfamily
EEFEMGPG_01217 2.5e-172 oppF E Belongs to the ABC transporter superfamily
EEFEMGPG_01218 2e-230 S Putative glycosyl hydrolase domain
EEFEMGPG_01219 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EEFEMGPG_01220 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EEFEMGPG_01221 1.4e-108 yjbE P Integral membrane protein TerC family
EEFEMGPG_01222 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EEFEMGPG_01223 3.6e-221 yjbF S Competence protein
EEFEMGPG_01224 0.0 pepF E oligoendopeptidase F
EEFEMGPG_01225 5.8e-19
EEFEMGPG_01226 5.1e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EEFEMGPG_01227 4.8e-72 yjbI S Bacterial-like globin
EEFEMGPG_01228 4.5e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EEFEMGPG_01229 4.1e-101 yjbK S protein conserved in bacteria
EEFEMGPG_01230 2.7e-61 yjbL S Belongs to the UPF0738 family
EEFEMGPG_01231 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
EEFEMGPG_01232 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EEFEMGPG_01233 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EEFEMGPG_01234 1.4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EEFEMGPG_01235 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EEFEMGPG_01236 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EEFEMGPG_01237 4.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EEFEMGPG_01238 3.5e-213 thiO 1.4.3.19 E Glycine oxidase
EEFEMGPG_01239 1.4e-30 thiS H Thiamine biosynthesis
EEFEMGPG_01240 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EEFEMGPG_01241 9.9e-191 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EEFEMGPG_01242 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EEFEMGPG_01243 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EEFEMGPG_01244 2.5e-88 yjbX S Spore coat protein
EEFEMGPG_01245 2.6e-79 cotZ S Spore coat protein
EEFEMGPG_01246 8.1e-90 cotY S Spore coat protein Z
EEFEMGPG_01247 4.3e-70 cotX S Spore Coat Protein X and V domain
EEFEMGPG_01248 6.8e-21 cotW
EEFEMGPG_01249 1.4e-52 cotV S Spore Coat Protein X and V domain
EEFEMGPG_01250 4.8e-55 yjcA S Protein of unknown function (DUF1360)
EEFEMGPG_01254 3.8e-38 spoVIF S Stage VI sporulation protein F
EEFEMGPG_01255 0.0 yjcD 3.6.4.12 L DNA helicase
EEFEMGPG_01256 4.6e-36
EEFEMGPG_01257 2.7e-140 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EEFEMGPG_01258 4e-125 S ABC-2 type transporter
EEFEMGPG_01259 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
EEFEMGPG_01260 9.4e-36 K SpoVT / AbrB like domain
EEFEMGPG_01262 1.9e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EEFEMGPG_01263 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EEFEMGPG_01264 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
EEFEMGPG_01265 3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EEFEMGPG_01266 4.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EEFEMGPG_01268 1.2e-15
EEFEMGPG_01269 1e-21
EEFEMGPG_01270 1.3e-37
EEFEMGPG_01271 6.4e-29
EEFEMGPG_01272 2.1e-204 M nucleic acid phosphodiester bond hydrolysis
EEFEMGPG_01273 3e-93
EEFEMGPG_01276 1.2e-129
EEFEMGPG_01277 4.1e-09 ywlA S Uncharacterised protein family (UPF0715)
EEFEMGPG_01278 4e-12
EEFEMGPG_01279 1.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
EEFEMGPG_01280 3e-73 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
EEFEMGPG_01282 2.9e-165 bla 3.5.2.6 V beta-lactamase
EEFEMGPG_01283 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
EEFEMGPG_01284 8.5e-249 yfjF EGP Belongs to the major facilitator superfamily
EEFEMGPG_01285 7.9e-82 napB K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_01286 5e-220 ganA 3.2.1.89 G arabinogalactan
EEFEMGPG_01287 2.1e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EEFEMGPG_01288 2.4e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EEFEMGPG_01289 2.7e-216 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EEFEMGPG_01290 7.1e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EEFEMGPG_01291 2.6e-49 lacF 2.7.1.207 G phosphotransferase system
EEFEMGPG_01292 4.5e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
EEFEMGPG_01293 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
EEFEMGPG_01294 2.2e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EEFEMGPG_01297 8.1e-106 yhiD S MgtC SapB transporter
EEFEMGPG_01299 8.3e-21 yjfB S Putative motility protein
EEFEMGPG_01300 2.9e-69 T PhoQ Sensor
EEFEMGPG_01301 4.9e-102 yjgB S Domain of unknown function (DUF4309)
EEFEMGPG_01302 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EEFEMGPG_01303 7.4e-92 yjgD S Protein of unknown function (DUF1641)
EEFEMGPG_01304 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EEFEMGPG_01305 3.4e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EEFEMGPG_01306 2e-28
EEFEMGPG_01307 9.5e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EEFEMGPG_01308 4.6e-124 ybbM S transport system, permease component
EEFEMGPG_01309 1.7e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
EEFEMGPG_01310 7.9e-177 yjlA EG Putative multidrug resistance efflux transporter
EEFEMGPG_01311 6.1e-93 yjlB S Cupin domain
EEFEMGPG_01312 7e-66 yjlC S Protein of unknown function (DUF1641)
EEFEMGPG_01313 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
EEFEMGPG_01314 1.1e-277 uxaC 5.3.1.12 G glucuronate isomerase
EEFEMGPG_01315 1.1e-253 yjmB G symporter YjmB
EEFEMGPG_01316 3.4e-183 exuR K transcriptional
EEFEMGPG_01317 8.7e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
EEFEMGPG_01318 6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EEFEMGPG_01319 8.9e-87 T Transcriptional regulatory protein, C terminal
EEFEMGPG_01320 2e-130 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EEFEMGPG_01322 3.9e-131 MA20_18170 S membrane transporter protein
EEFEMGPG_01323 2.4e-78 yjoA S DinB family
EEFEMGPG_01324 4.9e-215 S response regulator aspartate phosphatase
EEFEMGPG_01326 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EEFEMGPG_01327 4.7e-61 yjqA S Bacterial PH domain
EEFEMGPG_01328 1.1e-109 yjqB S phage-related replication protein
EEFEMGPG_01329 1.8e-41 yjqC P Catalase
EEFEMGPG_01330 3.7e-97 ydbD P Catalase
EEFEMGPG_01331 1.3e-110 xkdA E IrrE N-terminal-like domain
EEFEMGPG_01332 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
EEFEMGPG_01334 2.2e-153 xkdC L Bacterial dnaA protein
EEFEMGPG_01337 2e-10 yqaO S Phage-like element PBSX protein XtrA
EEFEMGPG_01338 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EEFEMGPG_01339 2e-109 xtmA L phage terminase small subunit
EEFEMGPG_01340 1.8e-208 xtmB S phage terminase, large subunit
EEFEMGPG_01341 7.9e-242 yqbA S portal protein
EEFEMGPG_01342 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
EEFEMGPG_01343 1e-157 xkdG S Phage capsid family
EEFEMGPG_01344 5.7e-46 yqbG S Protein of unknown function (DUF3199)
EEFEMGPG_01345 4.2e-43 yqbH S Domain of unknown function (DUF3599)
EEFEMGPG_01346 2.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
EEFEMGPG_01347 4.9e-57 xkdJ
EEFEMGPG_01348 3.1e-14
EEFEMGPG_01349 1e-225 xkdK S Phage tail sheath C-terminal domain
EEFEMGPG_01350 2e-74 xkdM S Phage tail tube protein
EEFEMGPG_01351 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
EEFEMGPG_01352 3.4e-19
EEFEMGPG_01353 3.1e-202 xkdO L Transglycosylase SLT domain
EEFEMGPG_01354 1.5e-110 xkdP S Lysin motif
EEFEMGPG_01355 2.7e-161 xkdQ 3.2.1.96 G NLP P60 protein
EEFEMGPG_01356 7.2e-32 xkdR S Protein of unknown function (DUF2577)
EEFEMGPG_01357 5.5e-58 xkdS S Protein of unknown function (DUF2634)
EEFEMGPG_01358 1.8e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EEFEMGPG_01359 2.2e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EEFEMGPG_01360 2.1e-26
EEFEMGPG_01361 6.8e-186
EEFEMGPG_01363 1.7e-30 xkdX
EEFEMGPG_01364 3.1e-136 xepA
EEFEMGPG_01365 8.7e-38 xhlA S Haemolysin XhlA
EEFEMGPG_01366 2.5e-37 xhlB S SPP1 phage holin
EEFEMGPG_01367 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EEFEMGPG_01368 8.7e-23 spoIISB S Stage II sporulation protein SB
EEFEMGPG_01369 6.3e-134 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EEFEMGPG_01370 7.5e-175 pit P phosphate transporter
EEFEMGPG_01371 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EEFEMGPG_01372 4.2e-242 steT E amino acid
EEFEMGPG_01373 1.5e-180 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EEFEMGPG_01374 3e-311 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EEFEMGPG_01375 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EEFEMGPG_01377 1.1e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEFEMGPG_01378 2e-283 yubD P Major Facilitator Superfamily
EEFEMGPG_01380 6.5e-156 dppA E D-aminopeptidase
EEFEMGPG_01381 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01382 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEFEMGPG_01383 1e-190 dppD P Belongs to the ABC transporter superfamily
EEFEMGPG_01384 0.0 dppE E ABC transporter substrate-binding protein
EEFEMGPG_01385 1.9e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EEFEMGPG_01386 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EEFEMGPG_01387 3.2e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EEFEMGPG_01388 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
EEFEMGPG_01389 2.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
EEFEMGPG_01390 3.6e-157 ykgA E Amidinotransferase
EEFEMGPG_01391 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EEFEMGPG_01392 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EEFEMGPG_01393 9.4e-53 ykkC P Multidrug resistance protein
EEFEMGPG_01394 3.4e-49 ykkD P Multidrug resistance protein
EEFEMGPG_01395 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EEFEMGPG_01396 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EEFEMGPG_01397 6.2e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EEFEMGPG_01398 1.8e-69 ohrA O Organic hydroperoxide resistance protein
EEFEMGPG_01399 7.3e-71 ohrR K COG1846 Transcriptional regulators
EEFEMGPG_01401 9.3e-71 ohrB O Organic hydroperoxide resistance protein
EEFEMGPG_01402 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EEFEMGPG_01404 7.9e-197 M Glycosyl transferase family 2
EEFEMGPG_01405 9e-131 M PFAM Collagen triple helix repeat (20 copies)
EEFEMGPG_01406 3.2e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
EEFEMGPG_01407 1.2e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EEFEMGPG_01408 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EEFEMGPG_01409 1.5e-175 isp O Belongs to the peptidase S8 family
EEFEMGPG_01410 5.9e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EEFEMGPG_01411 2.1e-132 ykoC P Cobalt transport protein
EEFEMGPG_01412 4e-306 P ABC transporter, ATP-binding protein
EEFEMGPG_01413 1e-97 ykoE S ABC-type cobalt transport system, permease component
EEFEMGPG_01414 3e-245 ydhD M Glycosyl hydrolase
EEFEMGPG_01416 2.2e-238 mgtE P Acts as a magnesium transporter
EEFEMGPG_01417 5.4e-53 tnrA K transcriptional
EEFEMGPG_01418 1.9e-16
EEFEMGPG_01419 3.1e-26 ykoL
EEFEMGPG_01420 1.1e-80 ykoM K transcriptional
EEFEMGPG_01421 1.9e-98 ykoP G polysaccharide deacetylase
EEFEMGPG_01422 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EEFEMGPG_01423 2.5e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EEFEMGPG_01424 2.7e-100 ykoX S membrane-associated protein
EEFEMGPG_01425 3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EEFEMGPG_01426 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_01427 8.1e-120 rsgI S Anti-sigma factor N-terminus
EEFEMGPG_01428 2.5e-26 sspD S small acid-soluble spore protein
EEFEMGPG_01429 6.6e-125 ykrK S Domain of unknown function (DUF1836)
EEFEMGPG_01430 4.1e-156 htpX O Belongs to the peptidase M48B family
EEFEMGPG_01431 1.5e-239 ktrB P COG0168 Trk-type K transport systems, membrane components
EEFEMGPG_01432 3.8e-114 ydfR S Protein of unknown function (DUF421)
EEFEMGPG_01433 7.9e-24 ykzE
EEFEMGPG_01434 1.7e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EEFEMGPG_01435 0.0 kinE 2.7.13.3 T Histidine kinase
EEFEMGPG_01436 3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EEFEMGPG_01438 1.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EEFEMGPG_01439 1.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EEFEMGPG_01440 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EEFEMGPG_01441 1.1e-228 mtnE 2.6.1.83 E Aminotransferase
EEFEMGPG_01442 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EEFEMGPG_01443 4.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EEFEMGPG_01444 4.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EEFEMGPG_01445 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EEFEMGPG_01446 2.6e-10 S Spo0E like sporulation regulatory protein
EEFEMGPG_01447 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EEFEMGPG_01448 1.5e-77 ykvE K transcriptional
EEFEMGPG_01449 2.7e-127 motB N Flagellar motor protein
EEFEMGPG_01450 1.1e-136 motA N flagellar motor
EEFEMGPG_01451 1.1e-40 L transposase activity
EEFEMGPG_01452 1.3e-86 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_01453 8.2e-26 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_01454 0.0 clpE O Belongs to the ClpA ClpB family
EEFEMGPG_01455 1.4e-184 ykvI S membrane
EEFEMGPG_01456 8.7e-188
EEFEMGPG_01457 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EEFEMGPG_01458 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
EEFEMGPG_01459 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EEFEMGPG_01460 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EEFEMGPG_01462 6.4e-60 ykvN K HxlR-like helix-turn-helix
EEFEMGPG_01463 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
EEFEMGPG_01464 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EEFEMGPG_01465 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
EEFEMGPG_01466 1.1e-33 3.5.1.104 M LysM domain
EEFEMGPG_01467 2e-161 G Glycosyl hydrolases family 18
EEFEMGPG_01469 1.3e-44 ykvR S Protein of unknown function (DUF3219)
EEFEMGPG_01470 7.8e-25 ykvS S protein conserved in bacteria
EEFEMGPG_01471 2.3e-27
EEFEMGPG_01472 3.1e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
EEFEMGPG_01473 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_01474 2.7e-88 stoA CO thiol-disulfide
EEFEMGPG_01475 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EEFEMGPG_01476 3.7e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EEFEMGPG_01478 5.1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
EEFEMGPG_01479 5.1e-156 glcT K antiterminator
EEFEMGPG_01480 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_01481 2.1e-39 ptsH G phosphocarrier protein HPr
EEFEMGPG_01482 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EEFEMGPG_01483 6.1e-38 splA S Transcriptional regulator
EEFEMGPG_01484 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
EEFEMGPG_01485 6.5e-263 mcpC NT chemotaxis protein
EEFEMGPG_01486 3.1e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EEFEMGPG_01487 7.4e-93 ykwD J protein with SCP PR1 domains
EEFEMGPG_01488 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EEFEMGPG_01489 1.5e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
EEFEMGPG_01490 8.7e-215 patA 2.6.1.1 E Aminotransferase
EEFEMGPG_01491 2.3e-09
EEFEMGPG_01492 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
EEFEMGPG_01493 1.4e-83 ykyB S YkyB-like protein
EEFEMGPG_01494 3e-240 ykuC EGP Major facilitator Superfamily
EEFEMGPG_01495 9.2e-89 ykuD S protein conserved in bacteria
EEFEMGPG_01496 6.8e-156 ykuE S Metallophosphoesterase
EEFEMGPG_01497 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_01499 1.5e-233 ykuI T Diguanylate phosphodiesterase
EEFEMGPG_01500 3.9e-37 ykuJ S protein conserved in bacteria
EEFEMGPG_01501 1.9e-92 ykuK S Ribonuclease H-like
EEFEMGPG_01502 2.1e-25 ykzF S Antirepressor AbbA
EEFEMGPG_01503 1e-75 ykuL S CBS domain
EEFEMGPG_01504 4.6e-168 ccpC K Transcriptional regulator
EEFEMGPG_01505 6.1e-90 fld C Flavodoxin
EEFEMGPG_01506 3.6e-168 ykuO
EEFEMGPG_01507 2.3e-78 fld C Flavodoxin
EEFEMGPG_01508 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EEFEMGPG_01509 2.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EEFEMGPG_01510 4.8e-38 ykuS S Belongs to the UPF0180 family
EEFEMGPG_01511 1.1e-139 ykuT M Mechanosensitive ion channel
EEFEMGPG_01512 7.9e-79 ykuV CO thiol-disulfide
EEFEMGPG_01513 1.5e-98 rok K Repressor of ComK
EEFEMGPG_01514 8.6e-163 yknT
EEFEMGPG_01515 2.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EEFEMGPG_01516 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EEFEMGPG_01517 1.9e-242 moeA 2.10.1.1 H molybdopterin
EEFEMGPG_01518 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EEFEMGPG_01519 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EEFEMGPG_01520 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EEFEMGPG_01521 6.4e-104 yknW S Yip1 domain
EEFEMGPG_01522 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEFEMGPG_01523 6.1e-123 macB V ABC transporter, ATP-binding protein
EEFEMGPG_01524 3.2e-212 yknZ V ABC transporter (permease)
EEFEMGPG_01525 2.4e-133 fruR K Transcriptional regulator
EEFEMGPG_01526 2.6e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EEFEMGPG_01527 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EEFEMGPG_01528 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EEFEMGPG_01529 1.5e-37 ykoA
EEFEMGPG_01530 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EEFEMGPG_01531 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEFEMGPG_01532 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EEFEMGPG_01533 5.5e-12 S Uncharacterized protein YkpC
EEFEMGPG_01534 6.9e-184 mreB D Rod-share determining protein MreBH
EEFEMGPG_01535 2.1e-45 abrB K of stationary sporulation gene expression
EEFEMGPG_01536 1.1e-245 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EEFEMGPG_01537 4.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EEFEMGPG_01538 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
EEFEMGPG_01539 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EEFEMGPG_01540 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EEFEMGPG_01541 8.2e-31 ykzG S Belongs to the UPF0356 family
EEFEMGPG_01542 8e-148 ykrA S hydrolases of the HAD superfamily
EEFEMGPG_01543 4.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EEFEMGPG_01545 5.9e-104 recN L Putative cell-wall binding lipoprotein
EEFEMGPG_01546 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_01547 0.0 Q Polyketide synthase of type I
EEFEMGPG_01548 0.0 Q polyketide synthase
EEFEMGPG_01549 0.0 Q Polyketide synthase of type I
EEFEMGPG_01550 0.0 Q Polyketide synthase of type I
EEFEMGPG_01551 0.0 Q Polyketide synthase of type I
EEFEMGPG_01552 0.0 Q Polyketide synthase of type I
EEFEMGPG_01553 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
EEFEMGPG_01554 5.8e-213 V Beta-lactamase
EEFEMGPG_01555 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EEFEMGPG_01556 4.2e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EEFEMGPG_01557 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EEFEMGPG_01558 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EEFEMGPG_01559 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EEFEMGPG_01560 4.1e-139 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
EEFEMGPG_01561 3.8e-276 speA 4.1.1.19 E Arginine
EEFEMGPG_01562 1.6e-42 yktA S Belongs to the UPF0223 family
EEFEMGPG_01563 4.9e-119 yktB S Belongs to the UPF0637 family
EEFEMGPG_01564 9.7e-25 ykzI
EEFEMGPG_01565 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
EEFEMGPG_01566 1.2e-82 ykzC S Acetyltransferase (GNAT) family
EEFEMGPG_01567 6.1e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EEFEMGPG_01568 1.7e-13 sigC S Putative zinc-finger
EEFEMGPG_01569 1.3e-39 ylaE
EEFEMGPG_01570 6.7e-24 S Family of unknown function (DUF5325)
EEFEMGPG_01571 0.0 typA T GTP-binding protein TypA
EEFEMGPG_01572 1.7e-48 ylaH S YlaH-like protein
EEFEMGPG_01573 1e-33 ylaI S protein conserved in bacteria
EEFEMGPG_01574 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EEFEMGPG_01575 2.2e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EEFEMGPG_01576 1.1e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EEFEMGPG_01577 7e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
EEFEMGPG_01578 8.7e-44 ylaN S Belongs to the UPF0358 family
EEFEMGPG_01579 2.9e-213 ftsW D Belongs to the SEDS family
EEFEMGPG_01580 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EEFEMGPG_01581 4.5e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EEFEMGPG_01582 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EEFEMGPG_01583 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EEFEMGPG_01584 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EEFEMGPG_01585 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EEFEMGPG_01586 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EEFEMGPG_01587 9.7e-166 ctaG S cytochrome c oxidase
EEFEMGPG_01588 2.2e-60 ylbA S YugN-like family
EEFEMGPG_01589 1.4e-72 ylbB T COG0517 FOG CBS domain
EEFEMGPG_01590 2.1e-199 ylbC S protein with SCP PR1 domains
EEFEMGPG_01591 6.5e-56 ylbD S Putative coat protein
EEFEMGPG_01592 8.8e-37 ylbE S YlbE-like protein
EEFEMGPG_01593 1.2e-71 ylbF S Belongs to the UPF0342 family
EEFEMGPG_01594 5.5e-43 ylbG S UPF0298 protein
EEFEMGPG_01596 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
EEFEMGPG_01597 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EEFEMGPG_01598 9.8e-217 ylbJ S Sporulation integral membrane protein YlbJ
EEFEMGPG_01599 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
EEFEMGPG_01600 2.1e-188 ylbL T Belongs to the peptidase S16 family
EEFEMGPG_01601 1.2e-44 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_01602 7.7e-138 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_01603 1.2e-230 ylbM S Belongs to the UPF0348 family
EEFEMGPG_01604 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
EEFEMGPG_01605 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EEFEMGPG_01606 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EEFEMGPG_01607 1.2e-88 ylbP K n-acetyltransferase
EEFEMGPG_01608 2.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEFEMGPG_01609 2.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EEFEMGPG_01610 8.9e-78 mraZ K Belongs to the MraZ family
EEFEMGPG_01611 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EEFEMGPG_01612 8.3e-52 ftsL D Essential cell division protein
EEFEMGPG_01613 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EEFEMGPG_01614 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EEFEMGPG_01615 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EEFEMGPG_01616 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EEFEMGPG_01617 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EEFEMGPG_01618 4.8e-185 spoVE D Belongs to the SEDS family
EEFEMGPG_01619 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EEFEMGPG_01620 4e-167 murB 1.3.1.98 M cell wall formation
EEFEMGPG_01621 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EEFEMGPG_01622 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EEFEMGPG_01623 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EEFEMGPG_01624 0.0 bpr O COG1404 Subtilisin-like serine proteases
EEFEMGPG_01625 8.3e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EEFEMGPG_01626 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_01627 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_01628 2.9e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EEFEMGPG_01629 1.7e-256 argE 3.5.1.16 E Acetylornithine deacetylase
EEFEMGPG_01630 2.2e-38 ylmC S sporulation protein
EEFEMGPG_01631 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EEFEMGPG_01632 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EEFEMGPG_01633 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EEFEMGPG_01634 5.2e-41 yggT S membrane
EEFEMGPG_01635 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EEFEMGPG_01636 8.9e-68 divIVA D Cell division initiation protein
EEFEMGPG_01637 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EEFEMGPG_01638 3.4e-64 dksA T COG1734 DnaK suppressor protein
EEFEMGPG_01639 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EEFEMGPG_01640 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EEFEMGPG_01641 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EEFEMGPG_01642 1.8e-232 pyrP F Xanthine uracil
EEFEMGPG_01643 4.8e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EEFEMGPG_01644 6.6e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EEFEMGPG_01645 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EEFEMGPG_01646 0.0 carB 6.3.5.5 F Belongs to the CarB family
EEFEMGPG_01647 5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EEFEMGPG_01648 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EEFEMGPG_01649 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EEFEMGPG_01650 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EEFEMGPG_01652 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EEFEMGPG_01653 1.8e-179 cysP P phosphate transporter
EEFEMGPG_01654 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EEFEMGPG_01655 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EEFEMGPG_01656 9.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EEFEMGPG_01657 1.3e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EEFEMGPG_01658 2e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EEFEMGPG_01659 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EEFEMGPG_01660 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EEFEMGPG_01661 2.9e-154 yloC S stress-induced protein
EEFEMGPG_01662 1.5e-40 ylzA S Belongs to the UPF0296 family
EEFEMGPG_01663 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EEFEMGPG_01664 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EEFEMGPG_01665 3.7e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EEFEMGPG_01666 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EEFEMGPG_01667 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EEFEMGPG_01668 3.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EEFEMGPG_01669 1.5e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EEFEMGPG_01670 3.4e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EEFEMGPG_01671 3.9e-139 stp 3.1.3.16 T phosphatase
EEFEMGPG_01672 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EEFEMGPG_01673 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EEFEMGPG_01674 9.8e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EEFEMGPG_01675 9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
EEFEMGPG_01676 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EEFEMGPG_01677 5.5e-59 asp S protein conserved in bacteria
EEFEMGPG_01678 1.1e-303 yloV S kinase related to dihydroxyacetone kinase
EEFEMGPG_01679 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
EEFEMGPG_01680 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
EEFEMGPG_01681 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EEFEMGPG_01682 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EEFEMGPG_01683 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EEFEMGPG_01684 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_01685 4.6e-129 IQ reductase
EEFEMGPG_01686 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEFEMGPG_01687 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EEFEMGPG_01688 0.0 smc D Required for chromosome condensation and partitioning
EEFEMGPG_01689 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EEFEMGPG_01690 4.7e-140 S Phosphotransferase enzyme family
EEFEMGPG_01691 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EEFEMGPG_01692 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EEFEMGPG_01693 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EEFEMGPG_01694 1.7e-35 ylqC S Belongs to the UPF0109 family
EEFEMGPG_01695 1.3e-61 ylqD S YlqD protein
EEFEMGPG_01696 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EEFEMGPG_01697 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EEFEMGPG_01698 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EEFEMGPG_01699 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EEFEMGPG_01700 1.2e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EEFEMGPG_01701 1.7e-307 ylqG
EEFEMGPG_01702 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EEFEMGPG_01703 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EEFEMGPG_01704 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EEFEMGPG_01705 1.9e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EEFEMGPG_01706 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EEFEMGPG_01707 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EEFEMGPG_01708 7.2e-172 xerC L tyrosine recombinase XerC
EEFEMGPG_01709 2.6e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EEFEMGPG_01710 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EEFEMGPG_01711 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EEFEMGPG_01712 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EEFEMGPG_01713 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
EEFEMGPG_01714 2.5e-31 fliE N Flagellar hook-basal body
EEFEMGPG_01715 1.2e-262 fliF N The M ring may be actively involved in energy transduction
EEFEMGPG_01716 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EEFEMGPG_01717 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EEFEMGPG_01718 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EEFEMGPG_01719 4.5e-71 fliJ N Flagellar biosynthesis chaperone
EEFEMGPG_01720 9.1e-46 ylxF S MgtE intracellular N domain
EEFEMGPG_01721 1.2e-204 fliK N Flagellar hook-length control protein
EEFEMGPG_01722 1.4e-72 flgD N Flagellar basal body rod modification protein
EEFEMGPG_01723 4e-139 flgG N Flagellar basal body rod
EEFEMGPG_01724 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
EEFEMGPG_01725 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EEFEMGPG_01726 4.7e-181 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EEFEMGPG_01727 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EEFEMGPG_01728 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
EEFEMGPG_01729 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
EEFEMGPG_01730 2e-37 fliQ N Role in flagellar biosynthesis
EEFEMGPG_01731 4e-131 fliR N Flagellar biosynthetic protein FliR
EEFEMGPG_01732 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EEFEMGPG_01733 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EEFEMGPG_01734 3.3e-192 flhF N Flagellar biosynthesis regulator FlhF
EEFEMGPG_01735 5.4e-156 flhG D Belongs to the ParA family
EEFEMGPG_01736 6.6e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EEFEMGPG_01737 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EEFEMGPG_01738 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
EEFEMGPG_01739 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EEFEMGPG_01740 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EEFEMGPG_01741 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_01742 5.3e-54 ylxL
EEFEMGPG_01743 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
EEFEMGPG_01744 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EEFEMGPG_01745 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EEFEMGPG_01746 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EEFEMGPG_01747 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EEFEMGPG_01748 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
EEFEMGPG_01749 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EEFEMGPG_01750 1.5e-233 rasP M zinc metalloprotease
EEFEMGPG_01751 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EEFEMGPG_01752 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EEFEMGPG_01753 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EEFEMGPG_01754 5.4e-206 nusA K Participates in both transcription termination and antitermination
EEFEMGPG_01755 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
EEFEMGPG_01756 1.8e-47 ylxQ J ribosomal protein
EEFEMGPG_01757 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EEFEMGPG_01758 3.9e-44 ylxP S protein conserved in bacteria
EEFEMGPG_01759 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EEFEMGPG_01760 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EEFEMGPG_01761 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EEFEMGPG_01762 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EEFEMGPG_01763 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EEFEMGPG_01764 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EEFEMGPG_01765 3.6e-235 pepR S Belongs to the peptidase M16 family
EEFEMGPG_01766 2.6e-42 ymxH S YlmC YmxH family
EEFEMGPG_01767 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EEFEMGPG_01768 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EEFEMGPG_01769 3.8e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EEFEMGPG_01770 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EEFEMGPG_01771 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EEFEMGPG_01772 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EEFEMGPG_01773 1.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EEFEMGPG_01774 2.4e-30 S YlzJ-like protein
EEFEMGPG_01775 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EEFEMGPG_01776 1.8e-133 ymfC K Transcriptional regulator
EEFEMGPG_01777 2.4e-229 ymfD EGP Major facilitator Superfamily
EEFEMGPG_01778 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_01779 0.0 ydgH S drug exporters of the RND superfamily
EEFEMGPG_01780 1e-237 ymfF S Peptidase M16
EEFEMGPG_01781 7.5e-244 ymfH S zinc protease
EEFEMGPG_01782 1.3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EEFEMGPG_01783 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
EEFEMGPG_01784 3.5e-143 ymfK S Protein of unknown function (DUF3388)
EEFEMGPG_01785 1.2e-123 ymfM S protein conserved in bacteria
EEFEMGPG_01786 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EEFEMGPG_01787 6.4e-232 cinA 3.5.1.42 S Belongs to the CinA family
EEFEMGPG_01788 2.4e-187 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EEFEMGPG_01789 1.1e-193 pbpX V Beta-lactamase
EEFEMGPG_01790 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
EEFEMGPG_01791 1.1e-152 ymdB S protein conserved in bacteria
EEFEMGPG_01792 1.2e-36 spoVS S Stage V sporulation protein S
EEFEMGPG_01793 3.5e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EEFEMGPG_01794 1.3e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EEFEMGPG_01795 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EEFEMGPG_01796 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EEFEMGPG_01797 1.7e-88 cotE S Spore coat protein
EEFEMGPG_01798 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EEFEMGPG_01799 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EEFEMGPG_01800 1.8e-56
EEFEMGPG_01801 8.5e-23 S Hypothetical protein (DUF2513)
EEFEMGPG_01802 1.7e-37
EEFEMGPG_01804 6.2e-60 S HNH endonuclease
EEFEMGPG_01805 2.2e-39
EEFEMGPG_01806 6.4e-174 A Pre-toxin TG
EEFEMGPG_01808 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
EEFEMGPG_01809 9.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_01810 1.9e-183 pksD Q Acyl transferase domain
EEFEMGPG_01811 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_01812 6.5e-35 acpK IQ Phosphopantetheine attachment site
EEFEMGPG_01813 2.4e-242 pksG 2.3.3.10 I synthase
EEFEMGPG_01814 3.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
EEFEMGPG_01815 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EEFEMGPG_01816 0.0 rhiB IQ polyketide synthase
EEFEMGPG_01817 0.0 Q Polyketide synthase of type I
EEFEMGPG_01818 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
EEFEMGPG_01819 0.0 dhbF IQ polyketide synthase
EEFEMGPG_01820 0.0 pks13 HQ Beta-ketoacyl synthase
EEFEMGPG_01821 5.8e-230 cypA C Cytochrome P450
EEFEMGPG_01822 7.5e-79 nucB M Deoxyribonuclease NucA/NucB
EEFEMGPG_01823 2.3e-117 yoaK S Membrane
EEFEMGPG_01824 1.4e-62 ymzB
EEFEMGPG_01825 8.9e-256 aprX O Belongs to the peptidase S8 family
EEFEMGPG_01827 4.1e-127 ymaC S Replication protein
EEFEMGPG_01828 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
EEFEMGPG_01829 5.2e-54 ebrB P Small Multidrug Resistance protein
EEFEMGPG_01830 3.1e-48 ebrA P Small Multidrug Resistance protein
EEFEMGPG_01832 1.4e-47 ymaF S YmaF family
EEFEMGPG_01833 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EEFEMGPG_01834 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EEFEMGPG_01835 8.5e-44
EEFEMGPG_01836 1.8e-20 ymzA
EEFEMGPG_01837 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EEFEMGPG_01838 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEFEMGPG_01839 1.3e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEFEMGPG_01840 2.4e-110 ymaB S MutT family
EEFEMGPG_01841 3.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EEFEMGPG_01842 1.2e-96 spoVK O stage V sporulation protein K
EEFEMGPG_01843 6.3e-78 yokF 3.1.31.1 L RNA catabolic process
EEFEMGPG_01844 1.5e-92 G SMI1-KNR4 cell-wall
EEFEMGPG_01845 7.2e-165 V HNH endonuclease
EEFEMGPG_01846 2e-247 UW nuclease activity
EEFEMGPG_01847 2.5e-83 yokJ S SMI1 / KNR4 family (SUKH-1)
EEFEMGPG_01848 4e-60 S Protein of unknown function, DUF600
EEFEMGPG_01849 3.7e-43 yokK S SMI1 / KNR4 family
EEFEMGPG_01850 3.5e-74 S SMI1-KNR4 cell-wall
EEFEMGPG_01852 1.6e-129 yunB S Sporulation protein YunB (Spo_YunB)
EEFEMGPG_01853 1.2e-39 S YolD-like protein
EEFEMGPG_01854 5.5e-223 S impB/mucB/samB family C-terminal domain
EEFEMGPG_01856 9.6e-89 S response regulator aspartate phosphatase
EEFEMGPG_01859 2.3e-32 S Bacteriophage holin
EEFEMGPG_01861 7.1e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EEFEMGPG_01862 1.8e-281 M Pectate lyase superfamily protein
EEFEMGPG_01863 4.1e-94
EEFEMGPG_01865 2.7e-36
EEFEMGPG_01866 3.6e-30
EEFEMGPG_01867 2.2e-237 S Pfam Transposase IS66
EEFEMGPG_01868 1.2e-63 S Phage tail protein
EEFEMGPG_01869 0.0 S peptidoglycan catabolic process
EEFEMGPG_01870 2.3e-52
EEFEMGPG_01873 2.4e-173 xerH A Belongs to the 'phage' integrase family
EEFEMGPG_01874 1.7e-48
EEFEMGPG_01875 1.4e-57
EEFEMGPG_01876 1.6e-78 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EEFEMGPG_01877 3.5e-13
EEFEMGPG_01878 1.7e-49 S Domain of unknown function (DUF2479)
EEFEMGPG_01879 1.5e-48
EEFEMGPG_01881 7.8e-58
EEFEMGPG_01882 6.6e-96
EEFEMGPG_01883 4.3e-86
EEFEMGPG_01884 1.6e-104
EEFEMGPG_01886 1.2e-62
EEFEMGPG_01887 1.8e-78
EEFEMGPG_01888 1.2e-183
EEFEMGPG_01889 5.6e-92
EEFEMGPG_01890 4.8e-231
EEFEMGPG_01891 4e-260
EEFEMGPG_01892 0.0 gp17a S Terminase-like family
EEFEMGPG_01893 1.1e-172
EEFEMGPG_01897 3.1e-215 S hydrolase activity
EEFEMGPG_01900 2.7e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EEFEMGPG_01901 0.0
EEFEMGPG_01905 1.1e-57 ftsZ D Tubulin/FtsZ family, GTPase domain
EEFEMGPG_01907 2.3e-95
EEFEMGPG_01908 5.9e-214
EEFEMGPG_01910 4.1e-199 3.1.21.3 L Domain of unknown function (DUF4942)
EEFEMGPG_01913 1.8e-07
EEFEMGPG_01914 1.1e-20 I Acyltransferase family
EEFEMGPG_01916 1.1e-45
EEFEMGPG_01920 2.9e-52
EEFEMGPG_01929 9e-79
EEFEMGPG_01935 1.6e-37 L Belongs to the 'phage' integrase family
EEFEMGPG_01936 3.9e-190
EEFEMGPG_01937 2.2e-33
EEFEMGPG_01938 5.3e-12 K Transcriptional regulator
EEFEMGPG_01942 5.9e-51 S dUTPase
EEFEMGPG_01943 2.3e-13 S YopX protein
EEFEMGPG_01949 1.8e-64
EEFEMGPG_01955 1.8e-74
EEFEMGPG_01960 1.8e-68
EEFEMGPG_01962 5.4e-71
EEFEMGPG_01964 7.8e-138 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
EEFEMGPG_01965 2.6e-126 yoqW S Belongs to the SOS response-associated peptidase family
EEFEMGPG_01968 8.7e-14 S YopX protein
EEFEMGPG_01970 1.5e-83 S Pfam:DUF867
EEFEMGPG_01971 3.8e-183 M Parallel beta-helix repeats
EEFEMGPG_01972 7.1e-20 M Parallel beta-helix repeats
EEFEMGPG_01976 1.2e-70 nrnB S phosphohydrolase (DHH superfamily)
EEFEMGPG_01977 7.7e-169
EEFEMGPG_01978 7.7e-160 S AAA domain
EEFEMGPG_01980 3.6e-242 3.6.4.12 L DnaB-like helicase C terminal domain
EEFEMGPG_01981 2.7e-148 3.6.4.12 L DNA primase activity
EEFEMGPG_01982 9.2e-171 S PD-(D/E)XK nuclease superfamily
EEFEMGPG_01983 3.8e-291 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
EEFEMGPG_01984 1.8e-24 DR0488 S protein conserved in bacteria
EEFEMGPG_01987 1e-69 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
EEFEMGPG_01988 3.6e-88 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EEFEMGPG_01990 2.3e-61 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EEFEMGPG_01994 1.8e-11
EEFEMGPG_01997 1.5e-23 S hydrolase activity
EEFEMGPG_01998 9.3e-19
EEFEMGPG_02006 3.1e-55 S NrdI Flavodoxin like
EEFEMGPG_02007 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEFEMGPG_02009 2.4e-176 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEFEMGPG_02010 3.6e-22 O Glutaredoxin
EEFEMGPG_02012 2.1e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EEFEMGPG_02016 9.3e-51 S Protein of unknown function (DUF1643)
EEFEMGPG_02017 2.8e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EEFEMGPG_02018 9.8e-30 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EEFEMGPG_02027 5.5e-30 sspB S spore protein
EEFEMGPG_02028 4.5e-165 S Calcineurin-like phosphoesterase
EEFEMGPG_02033 1.6e-36 S Macro domain
EEFEMGPG_02034 3.4e-90 recU L DNA recombination
EEFEMGPG_02036 7.9e-249 cisA2 L Recombinase
EEFEMGPG_02037 5.1e-69 spoVK O stage V sporulation protein K
EEFEMGPG_02038 4.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EEFEMGPG_02039 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EEFEMGPG_02040 4.3e-68 glnR K transcriptional
EEFEMGPG_02041 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
EEFEMGPG_02043 2.9e-30
EEFEMGPG_02044 1.9e-90 yokH G SMI1 / KNR4 family
EEFEMGPG_02045 9.7e-224 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EEFEMGPG_02046 2.4e-51 S SMI1-KNR4 cell-wall
EEFEMGPG_02047 2e-65 yokK S SMI1 / KNR4 family
EEFEMGPG_02048 1.2e-210 mrjp G Major royal jelly protein
EEFEMGPG_02049 5.6e-253 xynT G MFS/sugar transport protein
EEFEMGPG_02050 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EEFEMGPG_02051 1.2e-208 xylR GK ROK family
EEFEMGPG_02052 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EEFEMGPG_02053 2.9e-287 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
EEFEMGPG_02054 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EEFEMGPG_02058 5.4e-17
EEFEMGPG_02059 7.8e-55 dinB S DinB family
EEFEMGPG_02060 3.9e-187 adhP 1.1.1.1 C alcohol dehydrogenase
EEFEMGPG_02061 1.9e-16
EEFEMGPG_02062 1.5e-19 yoaW
EEFEMGPG_02064 2.2e-142 yoaP 3.1.3.18 K YoaP-like
EEFEMGPG_02065 5.1e-101 J Acetyltransferase (GNAT) domain
EEFEMGPG_02067 4.8e-119 ynaE S Domain of unknown function (DUF3885)
EEFEMGPG_02068 2.7e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_02069 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
EEFEMGPG_02071 2.6e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EEFEMGPG_02072 3e-93 yvgO
EEFEMGPG_02074 0.0 yobO M Pectate lyase superfamily protein
EEFEMGPG_02075 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EEFEMGPG_02076 2.3e-145 yndL S Replication protein
EEFEMGPG_02077 1.6e-07
EEFEMGPG_02078 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
EEFEMGPG_02079 2.4e-72 yndM S Protein of unknown function (DUF2512)
EEFEMGPG_02080 1.6e-12 yoaW
EEFEMGPG_02081 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EEFEMGPG_02082 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EEFEMGPG_02083 3.5e-112 yneB L resolvase
EEFEMGPG_02084 9.8e-33 ynzC S UPF0291 protein
EEFEMGPG_02085 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EEFEMGPG_02086 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
EEFEMGPG_02087 2.3e-28 yneF S UPF0154 protein
EEFEMGPG_02088 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
EEFEMGPG_02089 1.7e-125 ccdA O cytochrome c biogenesis protein
EEFEMGPG_02090 1e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EEFEMGPG_02091 3.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EEFEMGPG_02092 2.5e-74 yneK S Protein of unknown function (DUF2621)
EEFEMGPG_02093 3.2e-62 hspX O Spore coat protein
EEFEMGPG_02094 2.3e-19 sspP S Belongs to the SspP family
EEFEMGPG_02095 7.5e-15 sspO S Belongs to the SspO family
EEFEMGPG_02096 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EEFEMGPG_02097 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EEFEMGPG_02099 7.1e-18 tlp S Belongs to the Tlp family
EEFEMGPG_02100 8.3e-75 yneP S Thioesterase-like superfamily
EEFEMGPG_02101 4.4e-54 yneQ
EEFEMGPG_02102 1.3e-50 yneR S Belongs to the HesB IscA family
EEFEMGPG_02103 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EEFEMGPG_02104 1.5e-68 yccU S CoA-binding protein
EEFEMGPG_02105 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EEFEMGPG_02106 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EEFEMGPG_02107 6e-13
EEFEMGPG_02108 5.1e-41 ynfC
EEFEMGPG_02109 1.5e-248 agcS E Sodium alanine symporter
EEFEMGPG_02110 4.4e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
EEFEMGPG_02111 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
EEFEMGPG_02112 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
EEFEMGPG_02113 2.4e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EEFEMGPG_02114 1.1e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_02115 4.9e-182 kdgR_1 K transcriptional
EEFEMGPG_02116 2.9e-224 exuT G Sugar (and other) transporter
EEFEMGPG_02117 1.2e-157 yndG S DoxX-like family
EEFEMGPG_02118 8.3e-46 yndH S Domain of unknown function (DUF4166)
EEFEMGPG_02119 1.4e-273 yndJ S YndJ-like protein
EEFEMGPG_02120 1.7e-215 S Platelet-activating factor acetylhydrolase, isoform II
EEFEMGPG_02121 4.3e-291 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
EEFEMGPG_02122 4.8e-51 S Domain of unknown function (DUF4870)
EEFEMGPG_02123 1.2e-234 T PhoQ Sensor
EEFEMGPG_02124 3.4e-129 T Transcriptional regulatory protein, C terminal
EEFEMGPG_02125 5.1e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
EEFEMGPG_02126 3.4e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
EEFEMGPG_02127 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02128 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02129 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02130 1.3e-221 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_02131 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EEFEMGPG_02132 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EEFEMGPG_02133 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EEFEMGPG_02134 2.1e-255 yxjC EG COG2610 H gluconate symporter and related permeases
EEFEMGPG_02135 8.9e-223 bioI 1.14.14.46 C Cytochrome P450
EEFEMGPG_02136 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EEFEMGPG_02137 3e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EEFEMGPG_02138 4.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EEFEMGPG_02139 1.2e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EEFEMGPG_02140 5.3e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EEFEMGPG_02141 3.7e-72 yngA S membrane
EEFEMGPG_02142 3.8e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EEFEMGPG_02143 3.2e-104 yngC S SNARE associated Golgi protein
EEFEMGPG_02144 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EEFEMGPG_02145 5.8e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EEFEMGPG_02146 7.3e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EEFEMGPG_02147 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EEFEMGPG_02148 1.2e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EEFEMGPG_02149 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EEFEMGPG_02150 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EEFEMGPG_02151 7.8e-304 yngK T Glycosyl hydrolase-like 10
EEFEMGPG_02152 4.1e-65 yngL S Protein of unknown function (DUF1360)
EEFEMGPG_02153 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
EEFEMGPG_02154 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02155 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02156 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02157 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_02158 4.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EEFEMGPG_02159 3.8e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
EEFEMGPG_02160 3.5e-247 yoeA V MATE efflux family protein
EEFEMGPG_02161 7.6e-97 yoeB S IseA DL-endopeptidase inhibitor
EEFEMGPG_02163 3.5e-97 L Integrase
EEFEMGPG_02164 1.8e-34 yoeD G Helix-turn-helix domain
EEFEMGPG_02165 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EEFEMGPG_02166 1.4e-183 ybcL EGP Major facilitator Superfamily
EEFEMGPG_02167 1.8e-50 ybzH K Helix-turn-helix domain
EEFEMGPG_02168 7e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EEFEMGPG_02169 2.3e-156 gltR1 K Transcriptional regulator
EEFEMGPG_02170 1.3e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EEFEMGPG_02171 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EEFEMGPG_02172 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EEFEMGPG_02173 3.9e-146 gltC K Transcriptional regulator
EEFEMGPG_02174 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EEFEMGPG_02175 1.7e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EEFEMGPG_02176 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EEFEMGPG_02177 8.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_02178 6.8e-42 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EEFEMGPG_02179 2.3e-139 yoxB
EEFEMGPG_02180 1.5e-204 yoaB EGP Major facilitator Superfamily
EEFEMGPG_02181 1.9e-275 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
EEFEMGPG_02182 1.9e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEFEMGPG_02183 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEFEMGPG_02185 2.3e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_02186 4.3e-43
EEFEMGPG_02187 8.2e-76 S SMI1-KNR4 cell-wall
EEFEMGPG_02188 1e-294 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EEFEMGPG_02189 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EEFEMGPG_02190 2.1e-108 yobQ K helix_turn_helix, arabinose operon control protein
EEFEMGPG_02191 6.1e-14 yobQ K helix_turn_helix, arabinose operon control protein
EEFEMGPG_02192 2.8e-94 yobS K Transcriptional regulator
EEFEMGPG_02193 4.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EEFEMGPG_02194 1.9e-92 yobW
EEFEMGPG_02195 3.4e-55 czrA K transcriptional
EEFEMGPG_02196 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EEFEMGPG_02197 2.8e-91 yozB S membrane
EEFEMGPG_02198 2.5e-141 yocB J Protein required for attachment to host cells
EEFEMGPG_02199 1.9e-94 yocC
EEFEMGPG_02200 9.3e-186 yocD 3.4.17.13 V peptidase S66
EEFEMGPG_02202 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
EEFEMGPG_02203 0.0 recQ 3.6.4.12 L DNA helicase
EEFEMGPG_02204 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EEFEMGPG_02206 1.9e-54 dksA T general stress protein
EEFEMGPG_02207 1e-09 yocL
EEFEMGPG_02208 2.2e-08 yocN
EEFEMGPG_02209 5.8e-88 yocM O Belongs to the small heat shock protein (HSP20) family
EEFEMGPG_02210 1.4e-43 yozN
EEFEMGPG_02211 8.5e-37 yocN
EEFEMGPG_02212 2.4e-56 yozO S Bacterial PH domain
EEFEMGPG_02214 1.6e-31 yozC
EEFEMGPG_02215 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EEFEMGPG_02216 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EEFEMGPG_02217 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
EEFEMGPG_02218 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EEFEMGPG_02219 3.5e-161 yocS S -transporter
EEFEMGPG_02220 8.2e-142 S Metallo-beta-lactamase superfamily
EEFEMGPG_02221 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_02222 6.4e-54 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_02223 1.2e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EEFEMGPG_02224 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EEFEMGPG_02225 0.0 yojO P Von Willebrand factor
EEFEMGPG_02226 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
EEFEMGPG_02227 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EEFEMGPG_02228 4.7e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EEFEMGPG_02229 1.5e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EEFEMGPG_02230 2.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EEFEMGPG_02232 1.1e-240 norM V Multidrug efflux pump
EEFEMGPG_02233 1.7e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EEFEMGPG_02234 2.5e-126 yojG S deacetylase
EEFEMGPG_02235 3.7e-60 yojF S Protein of unknown function (DUF1806)
EEFEMGPG_02236 4.9e-23
EEFEMGPG_02237 7.8e-163 rarD S -transporter
EEFEMGPG_02238 1.1e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
EEFEMGPG_02240 1.6e-67 yodA S tautomerase
EEFEMGPG_02241 4.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
EEFEMGPG_02242 1.4e-56 yodB K transcriptional
EEFEMGPG_02243 4.5e-106 yodC C nitroreductase
EEFEMGPG_02244 6.1e-111 mhqD S Carboxylesterase
EEFEMGPG_02245 1.5e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
EEFEMGPG_02246 1.4e-19 S Protein of unknown function (DUF3311)
EEFEMGPG_02247 3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEFEMGPG_02248 5e-284 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
EEFEMGPG_02249 6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EEFEMGPG_02250 1.2e-132 yydK K Transcriptional regulator
EEFEMGPG_02251 1.8e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EEFEMGPG_02252 2.8e-128 yodH Q Methyltransferase
EEFEMGPG_02253 4.3e-34 yodI
EEFEMGPG_02254 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EEFEMGPG_02255 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EEFEMGPG_02257 3.3e-55 yodL S YodL-like
EEFEMGPG_02258 3.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
EEFEMGPG_02259 6.2e-24 yozD S YozD-like protein
EEFEMGPG_02261 4.9e-125 yodN
EEFEMGPG_02262 4.1e-36 yozE S Belongs to the UPF0346 family
EEFEMGPG_02263 8.3e-47 yokU S YokU-like protein, putative antitoxin
EEFEMGPG_02264 7.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
EEFEMGPG_02265 2.3e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EEFEMGPG_02266 1.4e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
EEFEMGPG_02267 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EEFEMGPG_02268 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EEFEMGPG_02269 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEFEMGPG_02270 1.1e-64 yosT L Bacterial transcription activator, effector binding domain
EEFEMGPG_02272 3.7e-145 yiiD K acetyltransferase
EEFEMGPG_02273 5.9e-249 cgeD M maturation of the outermost layer of the spore
EEFEMGPG_02274 7.3e-41 cgeC
EEFEMGPG_02275 4.1e-53 cgeA
EEFEMGPG_02276 3e-181 cgeB S Spore maturation protein
EEFEMGPG_02277 2.6e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EEFEMGPG_02278 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
EEFEMGPG_02284 5.9e-78
EEFEMGPG_02285 2.6e-08
EEFEMGPG_02288 5.6e-77 yoqH M LysM domain
EEFEMGPG_02289 9.6e-195 S aspartate phosphatase
EEFEMGPG_02291 2e-159 3.4.24.40 S amine dehydrogenase activity
EEFEMGPG_02294 1.4e-62 S SMI1-KNR4 cell-wall
EEFEMGPG_02295 3.1e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EEFEMGPG_02296 1.2e-83 G SMI1-KNR4 cell-wall
EEFEMGPG_02297 1.2e-76 yokF 3.1.31.1 L RNA catabolic process
EEFEMGPG_02298 9.6e-308 yokA L Recombinase
EEFEMGPG_02299 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
EEFEMGPG_02300 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EEFEMGPG_02301 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEFEMGPG_02302 4.7e-67 ypoP K transcriptional
EEFEMGPG_02303 5.5e-98 ypmS S protein conserved in bacteria
EEFEMGPG_02304 4.4e-135 ypmR E GDSL-like Lipase/Acylhydrolase
EEFEMGPG_02305 4.6e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EEFEMGPG_02306 2.6e-39 ypmP S Protein of unknown function (DUF2535)
EEFEMGPG_02307 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EEFEMGPG_02308 8.6e-179 pspF K Transcriptional regulator
EEFEMGPG_02309 1.2e-109 hlyIII S protein, Hemolysin III
EEFEMGPG_02310 9.3e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EEFEMGPG_02311 6.2e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EEFEMGPG_02312 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EEFEMGPG_02313 2.7e-114 ypjP S YpjP-like protein
EEFEMGPG_02314 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EEFEMGPG_02315 3.9e-75 yphP S Belongs to the UPF0403 family
EEFEMGPG_02316 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EEFEMGPG_02317 3.6e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
EEFEMGPG_02318 1.2e-30 ypgQ S phosphohydrolase
EEFEMGPG_02319 2.4e-57 ypgQ S phosphohydrolase
EEFEMGPG_02320 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EEFEMGPG_02321 4.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EEFEMGPG_02322 2.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EEFEMGPG_02323 1e-30 cspD K Cold-shock protein
EEFEMGPG_02324 3.3e-12 degR
EEFEMGPG_02325 1.2e-36 S Protein of unknown function (DUF2564)
EEFEMGPG_02326 1.5e-28 ypeQ S Zinc-finger
EEFEMGPG_02327 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EEFEMGPG_02328 5.8e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EEFEMGPG_02329 4.9e-69 rnhA 3.1.26.4 L Ribonuclease
EEFEMGPG_02331 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
EEFEMGPG_02333 2.2e-38 ypbS S Protein of unknown function (DUF2533)
EEFEMGPG_02334 0.0 ypbR S Dynamin family
EEFEMGPG_02335 9.3e-89 ypbQ S protein conserved in bacteria
EEFEMGPG_02336 1e-204 bcsA Q Naringenin-chalcone synthase
EEFEMGPG_02337 1.2e-106 J Acetyltransferase (GNAT) domain
EEFEMGPG_02338 7.5e-39 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EEFEMGPG_02340 8.2e-97 ydfR S Protein of unknown function (DUF421)
EEFEMGPG_02341 2.2e-99 yrdC 3.5.1.19 Q Isochorismatase family
EEFEMGPG_02343 5e-235 pbuX F xanthine
EEFEMGPG_02344 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EEFEMGPG_02345 2.1e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EEFEMGPG_02346 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EEFEMGPG_02348 6.6e-22 S YpzG-like protein
EEFEMGPG_02349 4.9e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EEFEMGPG_02350 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EEFEMGPG_02351 1.8e-98 ypsA S Belongs to the UPF0398 family
EEFEMGPG_02352 9.9e-33 cotD S Inner spore coat protein D
EEFEMGPG_02354 1.6e-235 yprB L RNase_H superfamily
EEFEMGPG_02355 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EEFEMGPG_02356 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EEFEMGPG_02357 1.2e-70 hspX O Belongs to the small heat shock protein (HSP20) family
EEFEMGPG_02358 2.8e-47 yppG S YppG-like protein
EEFEMGPG_02360 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
EEFEMGPG_02363 1.6e-185 yppC S Protein of unknown function (DUF2515)
EEFEMGPG_02364 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EEFEMGPG_02365 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EEFEMGPG_02366 3.7e-90 ypoC
EEFEMGPG_02367 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EEFEMGPG_02368 6.8e-130 dnaD L DNA replication protein DnaD
EEFEMGPG_02369 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
EEFEMGPG_02370 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EEFEMGPG_02371 4e-81 ypmB S protein conserved in bacteria
EEFEMGPG_02372 6.7e-23 ypmA S Protein of unknown function (DUF4264)
EEFEMGPG_02373 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EEFEMGPG_02374 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EEFEMGPG_02375 1.6e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EEFEMGPG_02376 1.2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EEFEMGPG_02377 8.1e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EEFEMGPG_02378 3.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EEFEMGPG_02379 2e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EEFEMGPG_02380 1.3e-131 bshB1 S proteins, LmbE homologs
EEFEMGPG_02381 4.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EEFEMGPG_02382 2.7e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EEFEMGPG_02383 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EEFEMGPG_02384 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_02385 1.5e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
EEFEMGPG_02386 5.1e-142 ypjB S sporulation protein
EEFEMGPG_02387 3.5e-103 ypjA S membrane
EEFEMGPG_02388 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EEFEMGPG_02389 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
EEFEMGPG_02390 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
EEFEMGPG_02391 1.9e-77 ypiF S Protein of unknown function (DUF2487)
EEFEMGPG_02392 4.8e-99 ypiB S Belongs to the UPF0302 family
EEFEMGPG_02393 7e-234 S COG0457 FOG TPR repeat
EEFEMGPG_02394 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EEFEMGPG_02395 1.2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EEFEMGPG_02396 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EEFEMGPG_02397 3.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EEFEMGPG_02398 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EEFEMGPG_02399 5.5e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EEFEMGPG_02400 1e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EEFEMGPG_02401 7e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EEFEMGPG_02402 9.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EEFEMGPG_02403 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EEFEMGPG_02404 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EEFEMGPG_02405 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EEFEMGPG_02406 1.2e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EEFEMGPG_02407 1.1e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EEFEMGPG_02408 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EEFEMGPG_02409 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EEFEMGPG_02410 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EEFEMGPG_02411 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EEFEMGPG_02412 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
EEFEMGPG_02413 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EEFEMGPG_02414 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EEFEMGPG_02415 2.4e-133 yphF
EEFEMGPG_02416 1.5e-16 yphE S Protein of unknown function (DUF2768)
EEFEMGPG_02417 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EEFEMGPG_02418 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EEFEMGPG_02419 3.2e-104 yphA
EEFEMGPG_02420 4.7e-08 S YpzI-like protein
EEFEMGPG_02421 2.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EEFEMGPG_02422 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
EEFEMGPG_02423 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EEFEMGPG_02424 1.4e-12 S Family of unknown function (DUF5359)
EEFEMGPG_02425 5.7e-62 ypfA M Flagellar protein YcgR
EEFEMGPG_02426 3.5e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EEFEMGPG_02427 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EEFEMGPG_02428 3.5e-120 prsW S Involved in the degradation of specific anti-sigma factors
EEFEMGPG_02429 7.7e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EEFEMGPG_02430 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EEFEMGPG_02431 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EEFEMGPG_02432 7.3e-149 ypbG S Calcineurin-like phosphoesterase superfamily domain
EEFEMGPG_02433 5.7e-85 ypbF S Protein of unknown function (DUF2663)
EEFEMGPG_02434 3.1e-75 ypbE M Lysin motif
EEFEMGPG_02435 9.9e-100 ypbD S metal-dependent membrane protease
EEFEMGPG_02436 9.4e-272 recQ 3.6.4.12 L DNA helicase
EEFEMGPG_02437 1.4e-198 ypbB 5.1.3.1 S protein conserved in bacteria
EEFEMGPG_02438 3.6e-41 fer C Ferredoxin
EEFEMGPG_02439 4.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EEFEMGPG_02440 2.2e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEFEMGPG_02441 1.6e-194 rsiX
EEFEMGPG_02442 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EEFEMGPG_02443 0.0 resE 2.7.13.3 T Histidine kinase
EEFEMGPG_02444 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_02445 2.7e-192 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EEFEMGPG_02446 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EEFEMGPG_02447 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EEFEMGPG_02448 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EEFEMGPG_02449 2.2e-88 spmB S Spore maturation protein
EEFEMGPG_02450 2e-103 spmA S Spore maturation protein
EEFEMGPG_02451 6.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EEFEMGPG_02452 2.9e-93 ypuI S Protein of unknown function (DUF3907)
EEFEMGPG_02453 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EEFEMGPG_02454 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EEFEMGPG_02456 6.4e-93 ypuF S Domain of unknown function (DUF309)
EEFEMGPG_02457 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EEFEMGPG_02458 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EEFEMGPG_02459 6.4e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEFEMGPG_02460 3.8e-111 ribE 2.5.1.9 H Riboflavin synthase
EEFEMGPG_02461 8.9e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEFEMGPG_02462 1.7e-49 ypuD
EEFEMGPG_02463 2.6e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EEFEMGPG_02464 1.4e-81 ccdC1 O Protein of unknown function (DUF1453)
EEFEMGPG_02465 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EEFEMGPG_02466 5.1e-154 ypuA S Secreted protein
EEFEMGPG_02467 1.5e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EEFEMGPG_02468 1.4e-270 spoVAF EG Stage V sporulation protein AF
EEFEMGPG_02469 1.8e-110 spoVAEA S stage V sporulation protein
EEFEMGPG_02470 3.8e-57 spoVAEB S stage V sporulation protein
EEFEMGPG_02471 5e-190 spoVAD I Stage V sporulation protein AD
EEFEMGPG_02472 2.1e-79 spoVAC S stage V sporulation protein AC
EEFEMGPG_02473 3e-60 spoVAB S Stage V sporulation protein AB
EEFEMGPG_02474 3.7e-111 spoVAA S Stage V sporulation protein AA
EEFEMGPG_02475 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_02476 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EEFEMGPG_02477 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EEFEMGPG_02478 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EEFEMGPG_02479 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EEFEMGPG_02480 1e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EEFEMGPG_02481 3.7e-165 xerD L recombinase XerD
EEFEMGPG_02482 3.7e-37 S Protein of unknown function (DUF4227)
EEFEMGPG_02483 1.9e-80 fur P Belongs to the Fur family
EEFEMGPG_02484 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EEFEMGPG_02485 3.8e-28 yqkK
EEFEMGPG_02486 5.7e-22
EEFEMGPG_02487 6.5e-243 mleA 1.1.1.38 C malic enzyme
EEFEMGPG_02488 1.2e-239 mleN C Na H antiporter
EEFEMGPG_02489 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EEFEMGPG_02490 8.5e-187 ansA 3.5.1.1 EJ L-asparaginase
EEFEMGPG_02491 3e-57 ansR K Transcriptional regulator
EEFEMGPG_02492 5.8e-219 yqxK 3.6.4.12 L DNA helicase
EEFEMGPG_02493 8.1e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EEFEMGPG_02495 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EEFEMGPG_02497 2.1e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EEFEMGPG_02498 3.2e-39 yqkC S Protein of unknown function (DUF2552)
EEFEMGPG_02499 7.7e-61 yqkB S Belongs to the HesB IscA family
EEFEMGPG_02500 4.3e-175 yqkA K GrpB protein
EEFEMGPG_02501 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
EEFEMGPG_02502 3.9e-89 yqjY K acetyltransferase
EEFEMGPG_02503 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEFEMGPG_02504 1.2e-58 S YolD-like protein
EEFEMGPG_02506 4.6e-186 yueF S transporter activity
EEFEMGPG_02508 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EEFEMGPG_02509 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
EEFEMGPG_02510 1e-251 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EEFEMGPG_02511 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_02512 1.1e-175 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EEFEMGPG_02513 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EEFEMGPG_02514 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EEFEMGPG_02515 3.2e-239 pksG 2.3.3.10 I synthase
EEFEMGPG_02516 8e-221 eryK 1.14.13.154 C Cytochrome P450
EEFEMGPG_02517 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EEFEMGPG_02518 0.0 Q Polyketide synthase of type I
EEFEMGPG_02519 0.0 pfaA Q Polyketide synthase of type I
EEFEMGPG_02520 0.0 pksJ Q Polyketide synthase of type I
EEFEMGPG_02521 0.0 Q Polyketide synthase of type I
EEFEMGPG_02522 0.0 1.1.1.320 Q Polyketide synthase of type I
EEFEMGPG_02523 0.0 pksJ Q Polyketide synthase of type I
EEFEMGPG_02524 5.5e-130 IQ reductase
EEFEMGPG_02525 4.1e-248 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EEFEMGPG_02528 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EEFEMGPG_02529 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
EEFEMGPG_02530 9.3e-08 S GlpM protein
EEFEMGPG_02531 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EEFEMGPG_02532 3e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EEFEMGPG_02533 1.9e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EEFEMGPG_02534 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EEFEMGPG_02535 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EEFEMGPG_02536 8.6e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEFEMGPG_02537 2.4e-25 yqzJ
EEFEMGPG_02538 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EEFEMGPG_02539 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EEFEMGPG_02540 5.3e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EEFEMGPG_02541 2.7e-73 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EEFEMGPG_02543 1.6e-94 yqjB S protein conserved in bacteria
EEFEMGPG_02544 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
EEFEMGPG_02545 6.5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EEFEMGPG_02546 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
EEFEMGPG_02547 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
EEFEMGPG_02548 1e-75 yqiW S Belongs to the UPF0403 family
EEFEMGPG_02549 1e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EEFEMGPG_02550 1.2e-204 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EEFEMGPG_02551 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EEFEMGPG_02552 2.5e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EEFEMGPG_02553 3.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EEFEMGPG_02554 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
EEFEMGPG_02555 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EEFEMGPG_02556 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EEFEMGPG_02557 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EEFEMGPG_02558 3.2e-34 yqzF S Protein of unknown function (DUF2627)
EEFEMGPG_02559 2.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EEFEMGPG_02560 8.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EEFEMGPG_02561 1.8e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EEFEMGPG_02562 6.1e-205 mmgC I acyl-CoA dehydrogenase
EEFEMGPG_02563 8.2e-154 hbdA 1.1.1.157 I Dehydrogenase
EEFEMGPG_02564 9.8e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
EEFEMGPG_02565 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EEFEMGPG_02566 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EEFEMGPG_02567 2.5e-17
EEFEMGPG_02568 1e-100 ytaF P Probably functions as a manganese efflux pump
EEFEMGPG_02569 1.8e-113 K Protein of unknown function (DUF1232)
EEFEMGPG_02571 4.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EEFEMGPG_02574 3.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EEFEMGPG_02575 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EEFEMGPG_02576 6.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
EEFEMGPG_02577 6e-305 recN L May be involved in recombinational repair of damaged DNA
EEFEMGPG_02578 3.9e-78 argR K Regulates arginine biosynthesis genes
EEFEMGPG_02579 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EEFEMGPG_02580 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EEFEMGPG_02581 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EEFEMGPG_02582 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EEFEMGPG_02583 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EEFEMGPG_02584 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EEFEMGPG_02585 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EEFEMGPG_02586 8.1e-67 yqhY S protein conserved in bacteria
EEFEMGPG_02587 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EEFEMGPG_02588 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EEFEMGPG_02589 2.5e-62 spoIIIAH S SpoIIIAH-like protein
EEFEMGPG_02590 1e-117 spoIIIAG S stage III sporulation protein AG
EEFEMGPG_02591 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EEFEMGPG_02592 6.3e-200 spoIIIAE S stage III sporulation protein AE
EEFEMGPG_02593 2.5e-41 spoIIIAD S Stage III sporulation protein AD
EEFEMGPG_02594 7.6e-29 spoIIIAC S stage III sporulation protein AC
EEFEMGPG_02595 8.3e-85 spoIIIAB S Stage III sporulation protein
EEFEMGPG_02596 4.2e-172 spoIIIAA S stage III sporulation protein AA
EEFEMGPG_02597 1.8e-36 yqhV S Protein of unknown function (DUF2619)
EEFEMGPG_02598 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EEFEMGPG_02599 3.2e-171 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EEFEMGPG_02600 3.7e-88 yqhR S Conserved membrane protein YqhR
EEFEMGPG_02601 8e-174 yqhQ S Protein of unknown function (DUF1385)
EEFEMGPG_02602 3.4e-62 yqhP
EEFEMGPG_02603 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
EEFEMGPG_02604 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EEFEMGPG_02605 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EEFEMGPG_02606 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
EEFEMGPG_02607 5.7e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EEFEMGPG_02608 6e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EEFEMGPG_02609 2e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EEFEMGPG_02610 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EEFEMGPG_02611 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
EEFEMGPG_02612 5.2e-23 sinI S Anti-repressor SinI
EEFEMGPG_02613 7.8e-55 sinR K transcriptional
EEFEMGPG_02614 3.3e-141 tasA S Cell division protein FtsN
EEFEMGPG_02615 1e-70 sipW 3.4.21.89 U Signal peptidase
EEFEMGPG_02616 9.4e-121 yqxM
EEFEMGPG_02617 1.3e-54 yqzG S Protein of unknown function (DUF3889)
EEFEMGPG_02618 2.3e-26 yqzE S YqzE-like protein
EEFEMGPG_02619 2.9e-63 S ComG operon protein 7
EEFEMGPG_02620 2.1e-67 comGF U Putative Competence protein ComGF
EEFEMGPG_02621 1.3e-19 comGE
EEFEMGPG_02622 3.1e-72 gspH NU Tfp pilus assembly protein FimT
EEFEMGPG_02623 8.9e-50 comGC U Required for transformation and DNA binding
EEFEMGPG_02624 1.7e-182 comGB NU COG1459 Type II secretory pathway, component PulF
EEFEMGPG_02625 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EEFEMGPG_02626 9e-186 corA P Mg2 transporter protein
EEFEMGPG_02627 5.7e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EEFEMGPG_02628 4.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EEFEMGPG_02630 2.1e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
EEFEMGPG_02631 3.1e-37 yqgY S Protein of unknown function (DUF2626)
EEFEMGPG_02632 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EEFEMGPG_02633 5.4e-20 yqgW S Protein of unknown function (DUF2759)
EEFEMGPG_02634 1.5e-49 yqgV S Thiamine-binding protein
EEFEMGPG_02635 1.2e-199 yqgU
EEFEMGPG_02636 1.1e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EEFEMGPG_02637 1.7e-179 glcK 2.7.1.2 G Glucokinase
EEFEMGPG_02638 7.4e-212 nhaC C Na H antiporter
EEFEMGPG_02639 4e-07 yqgO
EEFEMGPG_02640 6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EEFEMGPG_02641 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EEFEMGPG_02642 1.2e-50 yqzD
EEFEMGPG_02643 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EEFEMGPG_02644 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EEFEMGPG_02645 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EEFEMGPG_02646 1.8e-156 pstA P Phosphate transport system permease
EEFEMGPG_02647 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
EEFEMGPG_02648 8.4e-157 pstS P Phosphate
EEFEMGPG_02649 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EEFEMGPG_02650 2e-228 yqgE EGP Major facilitator superfamily
EEFEMGPG_02651 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EEFEMGPG_02652 6e-77 yqgC S protein conserved in bacteria
EEFEMGPG_02653 8.7e-131 yqgB S Protein of unknown function (DUF1189)
EEFEMGPG_02654 6.9e-47 yqfZ M LysM domain
EEFEMGPG_02655 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EEFEMGPG_02656 3e-52 yqfX S membrane
EEFEMGPG_02657 1.4e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EEFEMGPG_02658 2.9e-72 zur P Belongs to the Fur family
EEFEMGPG_02659 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_02660 9.3e-37 yqfT S Protein of unknown function (DUF2624)
EEFEMGPG_02661 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EEFEMGPG_02662 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EEFEMGPG_02663 8.1e-51 yqfQ S YqfQ-like protein
EEFEMGPG_02664 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EEFEMGPG_02665 7.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EEFEMGPG_02666 1.1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
EEFEMGPG_02667 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
EEFEMGPG_02668 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EEFEMGPG_02669 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EEFEMGPG_02670 6.1e-88 yaiI S Belongs to the UPF0178 family
EEFEMGPG_02671 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EEFEMGPG_02672 4.5e-112 ccpN K CBS domain
EEFEMGPG_02673 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EEFEMGPG_02674 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EEFEMGPG_02675 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
EEFEMGPG_02676 1.8e-16 S YqzL-like protein
EEFEMGPG_02677 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EEFEMGPG_02678 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EEFEMGPG_02679 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EEFEMGPG_02680 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EEFEMGPG_02681 0.0 yqfF S membrane-associated HD superfamily hydrolase
EEFEMGPG_02682 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
EEFEMGPG_02683 2.2e-213 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EEFEMGPG_02684 9.3e-46 yqfC S sporulation protein YqfC
EEFEMGPG_02685 3.4e-55 yqfB
EEFEMGPG_02686 1.6e-121 yqfA S UPF0365 protein
EEFEMGPG_02687 1.3e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EEFEMGPG_02688 1.2e-68 yqeY S Yqey-like protein
EEFEMGPG_02689 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EEFEMGPG_02690 6.6e-157 yqeW P COG1283 Na phosphate symporter
EEFEMGPG_02691 3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EEFEMGPG_02692 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EEFEMGPG_02693 4.6e-174 prmA J Methylates ribosomal protein L11
EEFEMGPG_02694 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EEFEMGPG_02695 0.0 dnaK O Heat shock 70 kDa protein
EEFEMGPG_02696 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EEFEMGPG_02697 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EEFEMGPG_02698 6.3e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
EEFEMGPG_02699 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EEFEMGPG_02700 3.8e-54 yqxA S Protein of unknown function (DUF3679)
EEFEMGPG_02701 1.4e-220 spoIIP M stage II sporulation protein P
EEFEMGPG_02702 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EEFEMGPG_02703 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
EEFEMGPG_02704 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
EEFEMGPG_02705 0.0 comEC S Competence protein ComEC
EEFEMGPG_02706 8e-105 comEB 3.5.4.12 F ComE operon protein 2
EEFEMGPG_02707 2.1e-55 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EEFEMGPG_02708 2.7e-33 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EEFEMGPG_02709 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EEFEMGPG_02710 2.2e-139 yqeM Q Methyltransferase
EEFEMGPG_02711 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EEFEMGPG_02712 5.6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EEFEMGPG_02713 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EEFEMGPG_02714 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EEFEMGPG_02715 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EEFEMGPG_02716 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EEFEMGPG_02717 2e-94 yqeG S hydrolase of the HAD superfamily
EEFEMGPG_02719 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
EEFEMGPG_02720 3.4e-140 3.5.1.104 G Polysaccharide deacetylase
EEFEMGPG_02721 4.2e-107 yqeD S SNARE associated Golgi protein
EEFEMGPG_02722 3.1e-38 2.3.1.57 K Acetyltransferase (GNAT) domain
EEFEMGPG_02723 1.1e-215 EGP Major facilitator Superfamily
EEFEMGPG_02724 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEFEMGPG_02725 2.9e-25 xkdS S Protein of unknown function (DUF2634)
EEFEMGPG_02726 5e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EEFEMGPG_02727 4.7e-20 xkdR S Protein of unknown function (DUF2577)
EEFEMGPG_02729 2e-136 yvgN 1.1.1.346 S Reductase
EEFEMGPG_02730 2.9e-70 K MerR family transcriptional regulator
EEFEMGPG_02731 1.5e-15 xkdG S Phage capsid family
EEFEMGPG_02732 1.4e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
EEFEMGPG_02733 2.5e-92 K Transcriptional regulator PadR-like family
EEFEMGPG_02734 3e-193 yobL S Bacterial EndoU nuclease
EEFEMGPG_02735 2.9e-20 S SMI1-KNR4 cell-wall
EEFEMGPG_02736 3.9e-70 ydeE K AraC family transcriptional regulator
EEFEMGPG_02737 1.7e-104 K Transcriptional regulator
EEFEMGPG_02738 2e-124 yecA E amino acid
EEFEMGPG_02739 3e-69 psiE S Belongs to the PsiE family
EEFEMGPG_02740 5.6e-239 yrkQ T Histidine kinase
EEFEMGPG_02741 2.9e-125 T Transcriptional regulator
EEFEMGPG_02742 2.6e-217 yrkO P Protein of unknown function (DUF418)
EEFEMGPG_02743 1.8e-101 yrkN K Acetyltransferase (GNAT) family
EEFEMGPG_02744 2e-97 adk 2.7.4.3 F adenylate kinase activity
EEFEMGPG_02745 3.5e-32 yyaR K acetyltransferase
EEFEMGPG_02746 4.4e-64 tetL EGP Major facilitator Superfamily
EEFEMGPG_02747 1.3e-80 yyaR K Acetyltransferase (GNAT) domain
EEFEMGPG_02748 4.7e-93 yrdA S DinB family
EEFEMGPG_02749 1e-145 S hydrolase
EEFEMGPG_02750 1.6e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EEFEMGPG_02751 1.2e-129 glvR K Helix-turn-helix domain, rpiR family
EEFEMGPG_02752 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
EEFEMGPG_02753 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EEFEMGPG_02754 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EEFEMGPG_02755 6.3e-184 romA S Beta-lactamase superfamily domain
EEFEMGPG_02756 1.4e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EEFEMGPG_02757 2.4e-164 yybE K Transcriptional regulator
EEFEMGPG_02758 6.5e-213 ynfM EGP Major facilitator Superfamily
EEFEMGPG_02759 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EEFEMGPG_02760 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EEFEMGPG_02761 1.5e-92 yrhH Q methyltransferase
EEFEMGPG_02763 8e-143 focA P Formate nitrite
EEFEMGPG_02764 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
EEFEMGPG_02765 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EEFEMGPG_02766 7e-81 yrhD S Protein of unknown function (DUF1641)
EEFEMGPG_02767 1.8e-34 yrhC S YrhC-like protein
EEFEMGPG_02768 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EEFEMGPG_02769 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EEFEMGPG_02770 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EEFEMGPG_02771 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EEFEMGPG_02772 4.1e-27 yrzA S Protein of unknown function (DUF2536)
EEFEMGPG_02773 3.4e-68 yrrS S Protein of unknown function (DUF1510)
EEFEMGPG_02774 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EEFEMGPG_02775 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EEFEMGPG_02776 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EEFEMGPG_02777 2.1e-246 yegQ O COG0826 Collagenase and related proteases
EEFEMGPG_02778 1.7e-173 yegQ O Peptidase U32
EEFEMGPG_02779 3e-116 yrrM 2.1.1.104 S O-methyltransferase
EEFEMGPG_02780 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EEFEMGPG_02781 7.1e-46 yrzB S Belongs to the UPF0473 family
EEFEMGPG_02782 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EEFEMGPG_02783 1.7e-41 yrzL S Belongs to the UPF0297 family
EEFEMGPG_02784 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EEFEMGPG_02785 6.4e-164 yrrI S AI-2E family transporter
EEFEMGPG_02786 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EEFEMGPG_02787 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
EEFEMGPG_02788 1.2e-109 gluC P ABC transporter
EEFEMGPG_02789 4.4e-107 glnP P ABC transporter
EEFEMGPG_02790 2.1e-08 S Protein of unknown function (DUF3918)
EEFEMGPG_02791 2.9e-30 yrzR
EEFEMGPG_02792 1.8e-83 yrrD S protein conserved in bacteria
EEFEMGPG_02793 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EEFEMGPG_02794 1.7e-18 S COG0457 FOG TPR repeat
EEFEMGPG_02795 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EEFEMGPG_02796 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
EEFEMGPG_02797 7.8e-64 cymR K Transcriptional regulator
EEFEMGPG_02798 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EEFEMGPG_02799 2.5e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EEFEMGPG_02800 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EEFEMGPG_02801 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
EEFEMGPG_02804 4.4e-278 lytH 3.5.1.28 M COG3103 SH3 domain protein
EEFEMGPG_02805 5.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EEFEMGPG_02806 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EEFEMGPG_02807 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEFEMGPG_02808 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EEFEMGPG_02809 3.3e-47 yrvD S Lipopolysaccharide assembly protein A domain
EEFEMGPG_02810 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EEFEMGPG_02811 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EEFEMGPG_02812 2.9e-50 yrzD S Post-transcriptional regulator
EEFEMGPG_02813 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_02814 9.5e-110 yrbG S membrane
EEFEMGPG_02815 2.4e-60 yrzE S Protein of unknown function (DUF3792)
EEFEMGPG_02816 2.5e-37 yajC U Preprotein translocase subunit YajC
EEFEMGPG_02817 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EEFEMGPG_02818 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EEFEMGPG_02819 1.6e-20 yrzS S Protein of unknown function (DUF2905)
EEFEMGPG_02820 8.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EEFEMGPG_02821 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EEFEMGPG_02822 1.1e-92 bofC S BofC C-terminal domain
EEFEMGPG_02824 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EEFEMGPG_02825 1e-146 safA M spore coat assembly protein SafA
EEFEMGPG_02826 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EEFEMGPG_02827 3.4e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EEFEMGPG_02828 5.9e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EEFEMGPG_02829 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
EEFEMGPG_02830 6.1e-94 niaR S small molecule binding protein (contains 3H domain)
EEFEMGPG_02831 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
EEFEMGPG_02832 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
EEFEMGPG_02833 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EEFEMGPG_02834 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EEFEMGPG_02835 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EEFEMGPG_02836 3.2e-56 ysxB J ribosomal protein
EEFEMGPG_02837 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EEFEMGPG_02838 1.2e-160 spoIVFB S Stage IV sporulation protein
EEFEMGPG_02839 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EEFEMGPG_02840 8e-143 minD D Belongs to the ParA family
EEFEMGPG_02841 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EEFEMGPG_02842 1.4e-84 mreD M shape-determining protein
EEFEMGPG_02843 1.2e-157 mreC M Involved in formation and maintenance of cell shape
EEFEMGPG_02844 4e-184 mreB D Rod shape-determining protein MreB
EEFEMGPG_02845 1.8e-127 radC E Belongs to the UPF0758 family
EEFEMGPG_02846 2e-100 maf D septum formation protein Maf
EEFEMGPG_02847 3.4e-135 spoIIB S Sporulation related domain
EEFEMGPG_02848 7.8e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EEFEMGPG_02849 3.9e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EEFEMGPG_02850 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EEFEMGPG_02851 2.1e-25
EEFEMGPG_02852 4.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EEFEMGPG_02853 1.4e-229 spoVID M stage VI sporulation protein D
EEFEMGPG_02854 6.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EEFEMGPG_02855 2.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
EEFEMGPG_02856 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EEFEMGPG_02857 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EEFEMGPG_02858 3.6e-146 hemX O cytochrome C
EEFEMGPG_02859 1.3e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EEFEMGPG_02860 1.3e-87 ysxD
EEFEMGPG_02861 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
EEFEMGPG_02862 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EEFEMGPG_02863 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EEFEMGPG_02864 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EEFEMGPG_02865 1.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EEFEMGPG_02866 5.4e-189 ysoA H Tetratricopeptide repeat
EEFEMGPG_02867 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EEFEMGPG_02868 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EEFEMGPG_02869 1.8e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EEFEMGPG_02870 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EEFEMGPG_02871 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EEFEMGPG_02872 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
EEFEMGPG_02873 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EEFEMGPG_02876 1.7e-127 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
EEFEMGPG_02877 1.5e-248 hsdM 2.1.1.72 L type I restriction-modification system
EEFEMGPG_02878 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
EEFEMGPG_02882 5.3e-92 ysnB S Phosphoesterase
EEFEMGPG_02883 2.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EEFEMGPG_02884 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EEFEMGPG_02885 8.1e-199 gerM S COG5401 Spore germination protein
EEFEMGPG_02886 2.3e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EEFEMGPG_02887 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EEFEMGPG_02888 2e-30 gerE K Transcriptional regulator
EEFEMGPG_02889 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EEFEMGPG_02890 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EEFEMGPG_02891 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EEFEMGPG_02892 4.8e-108 sdhC C succinate dehydrogenase
EEFEMGPG_02893 1.2e-79 yslB S Protein of unknown function (DUF2507)
EEFEMGPG_02894 1.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EEFEMGPG_02895 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EEFEMGPG_02896 2.5e-52 trxA O Belongs to the thioredoxin family
EEFEMGPG_02897 1.8e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EEFEMGPG_02898 1.1e-178 etfA C Electron transfer flavoprotein
EEFEMGPG_02899 2e-138 etfB C Electron transfer flavoprotein
EEFEMGPG_02900 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EEFEMGPG_02901 3.5e-103 fadR K Transcriptional regulator
EEFEMGPG_02902 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EEFEMGPG_02903 1.8e-124 ywbB S Protein of unknown function (DUF2711)
EEFEMGPG_02904 4.7e-67 yshE S membrane
EEFEMGPG_02905 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EEFEMGPG_02906 0.0 polX L COG1796 DNA polymerase IV (family X)
EEFEMGPG_02907 6.2e-83 cvpA S membrane protein, required for colicin V production
EEFEMGPG_02908 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EEFEMGPG_02909 1.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EEFEMGPG_02910 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EEFEMGPG_02911 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EEFEMGPG_02912 2.7e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEFEMGPG_02913 2e-32 sspI S Belongs to the SspI family
EEFEMGPG_02914 5.8e-205 ysfB KT regulator
EEFEMGPG_02915 8.2e-260 glcD 1.1.3.15 C FAD binding domain
EEFEMGPG_02916 7.8e-252 glcF C Glycolate oxidase
EEFEMGPG_02917 0.0 cstA T Carbon starvation protein
EEFEMGPG_02918 7.8e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EEFEMGPG_02919 1.1e-142 araQ G transport system permease
EEFEMGPG_02920 1.1e-167 araP P PFAM binding-protein-dependent transport systems inner membrane component
EEFEMGPG_02921 1.8e-253 araN G carbohydrate transport
EEFEMGPG_02922 2.3e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EEFEMGPG_02923 1.3e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EEFEMGPG_02924 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EEFEMGPG_02925 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
EEFEMGPG_02926 2.8e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EEFEMGPG_02927 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EEFEMGPG_02928 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
EEFEMGPG_02929 9.2e-68 ysdB S Sigma-w pathway protein YsdB
EEFEMGPG_02930 7.7e-42 ysdA S Membrane
EEFEMGPG_02931 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EEFEMGPG_02932 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EEFEMGPG_02933 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EEFEMGPG_02934 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EEFEMGPG_02935 4.8e-33 lrgA S effector of murein hydrolase LrgA
EEFEMGPG_02936 8.4e-131 lytT T COG3279 Response regulator of the LytR AlgR family
EEFEMGPG_02937 0.0 lytS 2.7.13.3 T Histidine kinase
EEFEMGPG_02938 1.6e-151 ysaA S HAD-hyrolase-like
EEFEMGPG_02939 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EEFEMGPG_02940 8e-154 ytxC S YtxC-like family
EEFEMGPG_02941 2.7e-109 ytxB S SNARE associated Golgi protein
EEFEMGPG_02942 4.3e-172 dnaI L Primosomal protein DnaI
EEFEMGPG_02943 4.5e-258 dnaB L Membrane attachment protein
EEFEMGPG_02944 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EEFEMGPG_02945 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EEFEMGPG_02946 6.7e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EEFEMGPG_02947 2e-67 ytcD K Transcriptional regulator
EEFEMGPG_02948 9.9e-206 ytbD EGP Major facilitator Superfamily
EEFEMGPG_02949 1.5e-160 ytbE S reductase
EEFEMGPG_02950 5.8e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EEFEMGPG_02951 9.5e-107 ytaF P Probably functions as a manganese efflux pump
EEFEMGPG_02952 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EEFEMGPG_02953 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEFEMGPG_02954 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
EEFEMGPG_02955 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_02956 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EEFEMGPG_02957 3.1e-242 icd 1.1.1.42 C isocitrate
EEFEMGPG_02958 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EEFEMGPG_02959 1.9e-47 yjdF S Protein of unknown function (DUF2992)
EEFEMGPG_02960 2.5e-72 yeaL S membrane
EEFEMGPG_02961 6.9e-193 ytvI S sporulation integral membrane protein YtvI
EEFEMGPG_02962 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EEFEMGPG_02963 1.3e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EEFEMGPG_02964 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EEFEMGPG_02965 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EEFEMGPG_02966 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EEFEMGPG_02967 1.3e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
EEFEMGPG_02968 0.0 dnaE 2.7.7.7 L DNA polymerase
EEFEMGPG_02969 3.2e-56 ytrH S Sporulation protein YtrH
EEFEMGPG_02970 5.1e-87 ytrI
EEFEMGPG_02971 5.8e-23
EEFEMGPG_02972 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EEFEMGPG_02973 3.1e-47 ytpI S YtpI-like protein
EEFEMGPG_02974 7.5e-239 ytoI K transcriptional regulator containing CBS domains
EEFEMGPG_02975 2.5e-129 ytkL S Belongs to the UPF0173 family
EEFEMGPG_02976 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_02978 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
EEFEMGPG_02979 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EEFEMGPG_02980 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EEFEMGPG_02981 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EEFEMGPG_02982 1.4e-184 ytxK 2.1.1.72 L DNA methylase
EEFEMGPG_02983 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EEFEMGPG_02984 1.6e-60 ytfJ S Sporulation protein YtfJ
EEFEMGPG_02985 6.5e-109 ytfI S Protein of unknown function (DUF2953)
EEFEMGPG_02986 4.5e-88 yteJ S RDD family
EEFEMGPG_02987 1.4e-181 sppA OU signal peptide peptidase SppA
EEFEMGPG_02988 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EEFEMGPG_02989 0.0 ytcJ S amidohydrolase
EEFEMGPG_02990 6.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EEFEMGPG_02991 3.9e-31 sspB S spore protein
EEFEMGPG_02992 4.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EEFEMGPG_02993 4.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
EEFEMGPG_02994 4e-240 braB E Component of the transport system for branched-chain amino acids
EEFEMGPG_02995 1.5e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EEFEMGPG_02996 7.8e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EEFEMGPG_02997 7.7e-109 yttP K Transcriptional regulator
EEFEMGPG_02998 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
EEFEMGPG_02999 2.7e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EEFEMGPG_03000 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EEFEMGPG_03001 1.2e-255 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EEFEMGPG_03002 6.4e-99 yokH G SMI1 / KNR4 family
EEFEMGPG_03004 1e-58 UW Hep Hag repeat protein
EEFEMGPG_03005 1.4e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EEFEMGPG_03006 2.5e-09
EEFEMGPG_03007 6.5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
EEFEMGPG_03009 1e-139 E GDSL-like Lipase/Acylhydrolase family
EEFEMGPG_03010 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EEFEMGPG_03011 4.4e-149 K Transcriptional regulator
EEFEMGPG_03012 2.6e-124 azlC E AzlC protein
EEFEMGPG_03013 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
EEFEMGPG_03014 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EEFEMGPG_03015 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EEFEMGPG_03016 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EEFEMGPG_03017 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
EEFEMGPG_03018 2.5e-230 acuC BQ histone deacetylase
EEFEMGPG_03019 1.4e-119 motS N Flagellar motor protein
EEFEMGPG_03020 5.1e-145 motA N flagellar motor
EEFEMGPG_03021 1.4e-181 ccpA K catabolite control protein A
EEFEMGPG_03022 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EEFEMGPG_03023 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
EEFEMGPG_03024 1.8e-16 ytxH S COG4980 Gas vesicle protein
EEFEMGPG_03025 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EEFEMGPG_03026 8.4e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EEFEMGPG_03027 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EEFEMGPG_03028 9.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EEFEMGPG_03029 3.7e-148 ytpQ S Belongs to the UPF0354 family
EEFEMGPG_03030 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EEFEMGPG_03031 4.5e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EEFEMGPG_03032 9.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EEFEMGPG_03033 1.7e-51 ytzB S small secreted protein
EEFEMGPG_03034 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EEFEMGPG_03035 2.1e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EEFEMGPG_03036 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EEFEMGPG_03037 3.9e-44 ytzH S YtzH-like protein
EEFEMGPG_03038 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
EEFEMGPG_03039 1.4e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EEFEMGPG_03040 3.5e-166 ytlQ
EEFEMGPG_03041 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EEFEMGPG_03042 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EEFEMGPG_03043 1.6e-268 pepV 3.5.1.18 E Dipeptidase
EEFEMGPG_03044 2e-228 pbuO S permease
EEFEMGPG_03045 4.2e-217 ythQ U Bacterial ABC transporter protein EcsB
EEFEMGPG_03046 4.1e-127 ythP V ABC transporter
EEFEMGPG_03047 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EEFEMGPG_03048 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EEFEMGPG_03049 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_03050 2.8e-235 ytfP S HI0933-like protein
EEFEMGPG_03051 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EEFEMGPG_03052 9e-26 yteV S Sporulation protein Cse60
EEFEMGPG_03053 2.6e-186 msmR K Transcriptional regulator
EEFEMGPG_03054 1.4e-245 msmE G Bacterial extracellular solute-binding protein
EEFEMGPG_03055 2.2e-168 amyD G Binding-protein-dependent transport system inner membrane component
EEFEMGPG_03056 4.1e-142 amyC P ABC transporter (permease)
EEFEMGPG_03057 1.4e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EEFEMGPG_03058 5.4e-86 M Acetyltransferase (GNAT) domain
EEFEMGPG_03059 5.6e-52 ytwF P Sulfurtransferase
EEFEMGPG_03060 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EEFEMGPG_03061 1.2e-52 ytvB S Protein of unknown function (DUF4257)
EEFEMGPG_03062 2.1e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EEFEMGPG_03063 7.7e-138 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_03064 1.2e-44 L COG2963 Transposase and inactivated derivatives
EEFEMGPG_03065 2.6e-206 yttB EGP Major facilitator Superfamily
EEFEMGPG_03066 3.6e-126 ywaF S Integral membrane protein
EEFEMGPG_03067 0.0 bceB V ABC transporter (permease)
EEFEMGPG_03068 5.8e-135 bceA V ABC transporter, ATP-binding protein
EEFEMGPG_03069 4.4e-164 T PhoQ Sensor
EEFEMGPG_03070 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_03071 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EEFEMGPG_03072 1.3e-125 ytrE V ABC transporter, ATP-binding protein
EEFEMGPG_03073 3.6e-142
EEFEMGPG_03074 2.9e-171 P ABC-2 family transporter protein
EEFEMGPG_03075 1.6e-148 S ABC-2 family transporter protein
EEFEMGPG_03076 1.6e-160 ytrB P abc transporter atp-binding protein
EEFEMGPG_03077 3.9e-66 ytrA K GntR family transcriptional regulator
EEFEMGPG_03078 7.4e-40 ytzC S Protein of unknown function (DUF2524)
EEFEMGPG_03079 3.1e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
EEFEMGPG_03080 1.3e-283 norB EGP COG0477 Permeases of the major facilitator superfamily
EEFEMGPG_03081 2.1e-190 yhcC S Fe-S oxidoreductase
EEFEMGPG_03082 8.7e-107 ytqB J Putative rRNA methylase
EEFEMGPG_03084 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EEFEMGPG_03085 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EEFEMGPG_03086 3.8e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
EEFEMGPG_03087 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EEFEMGPG_03088 7.4e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_03089 0.0 asnB 6.3.5.4 E Asparagine synthase
EEFEMGPG_03090 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EEFEMGPG_03091 2.4e-308 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EEFEMGPG_03092 1.6e-38 ytmB S Protein of unknown function (DUF2584)
EEFEMGPG_03093 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EEFEMGPG_03094 2.1e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EEFEMGPG_03095 1.6e-143 ytlC P ABC transporter
EEFEMGPG_03096 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EEFEMGPG_03097 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EEFEMGPG_03098 1.7e-61 ytkC S Bacteriophage holin family
EEFEMGPG_03099 1.6e-76 dps P Belongs to the Dps family
EEFEMGPG_03101 7.9e-76 ytkA S YtkA-like
EEFEMGPG_03102 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EEFEMGPG_03103 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EEFEMGPG_03104 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EEFEMGPG_03105 3e-40 rpmE2 J Ribosomal protein L31
EEFEMGPG_03106 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
EEFEMGPG_03107 1.9e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EEFEMGPG_03108 2.3e-24 S Domain of Unknown Function (DUF1540)
EEFEMGPG_03109 7e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EEFEMGPG_03110 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EEFEMGPG_03111 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EEFEMGPG_03112 9.3e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EEFEMGPG_03113 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EEFEMGPG_03114 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
EEFEMGPG_03115 2e-132 dksA T COG1734 DnaK suppressor protein
EEFEMGPG_03116 9e-78 tspO T membrane
EEFEMGPG_03125 7.8e-08
EEFEMGPG_03126 1.3e-09
EEFEMGPG_03133 1.6e-08
EEFEMGPG_03138 3.4e-39 S COG NOG14552 non supervised orthologous group
EEFEMGPG_03139 3.7e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
EEFEMGPG_03140 2e-179 yuaG 3.4.21.72 S protein conserved in bacteria
EEFEMGPG_03141 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EEFEMGPG_03142 7.4e-83 yuaE S DinB superfamily
EEFEMGPG_03143 2.7e-108 yuaD S MOSC domain
EEFEMGPG_03144 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
EEFEMGPG_03145 2.1e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EEFEMGPG_03146 1e-96 yuaC K Belongs to the GbsR family
EEFEMGPG_03147 2.1e-94 yuaB
EEFEMGPG_03148 2.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
EEFEMGPG_03149 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EEFEMGPG_03150 2.6e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EEFEMGPG_03151 5.1e-124 G Cupin
EEFEMGPG_03152 1.2e-52 yjcN
EEFEMGPG_03156 8.1e-133 S Aspartate phosphatase response regulator
EEFEMGPG_03157 8.9e-14
EEFEMGPG_03160 3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EEFEMGPG_03161 9e-196 yubA S transporter activity
EEFEMGPG_03162 2.1e-185 ygjR S Oxidoreductase
EEFEMGPG_03163 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EEFEMGPG_03164 3.8e-234 mcpA NT chemotaxis protein
EEFEMGPG_03165 3.2e-225 mcpA NT chemotaxis protein
EEFEMGPG_03166 1.5e-238 mcpA NT chemotaxis protein
EEFEMGPG_03167 5.3e-220 mcpA NT chemotaxis protein
EEFEMGPG_03168 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EEFEMGPG_03169 4.8e-41
EEFEMGPG_03170 1.5e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EEFEMGPG_03171 2.8e-78 yugU S Uncharacterised protein family UPF0047
EEFEMGPG_03172 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EEFEMGPG_03173 8.7e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EEFEMGPG_03174 1.9e-116 yugP S Zn-dependent protease
EEFEMGPG_03175 4.5e-18
EEFEMGPG_03176 6.7e-27 mstX S Membrane-integrating protein Mistic
EEFEMGPG_03177 1.8e-181 yugO P COG1226 Kef-type K transport systems
EEFEMGPG_03178 1.3e-72 yugN S YugN-like family
EEFEMGPG_03180 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
EEFEMGPG_03181 1.4e-96 S NADPH-dependent FMN reductase
EEFEMGPG_03182 1.4e-118 ycaC Q Isochorismatase family
EEFEMGPG_03183 2.1e-229 yugK C Dehydrogenase
EEFEMGPG_03184 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EEFEMGPG_03185 1.8e-34 yuzA S Domain of unknown function (DUF378)
EEFEMGPG_03186 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EEFEMGPG_03187 7.2e-209 yugH 2.6.1.1 E Aminotransferase
EEFEMGPG_03188 2e-83 alaR K Transcriptional regulator
EEFEMGPG_03189 1.1e-155 yugF I Hydrolase
EEFEMGPG_03190 1.4e-40 yugE S Domain of unknown function (DUF1871)
EEFEMGPG_03191 3.2e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EEFEMGPG_03192 4.3e-223 T PhoQ Sensor
EEFEMGPG_03193 3.1e-68 kapB G Kinase associated protein B
EEFEMGPG_03194 4.5e-118 kapD L the KinA pathway to sporulation
EEFEMGPG_03195 1.5e-185 yuxJ EGP Major facilitator Superfamily
EEFEMGPG_03196 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EEFEMGPG_03197 5e-72 yuxK S protein conserved in bacteria
EEFEMGPG_03198 9.3e-74 yufK S Family of unknown function (DUF5366)
EEFEMGPG_03199 5.8e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EEFEMGPG_03200 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
EEFEMGPG_03201 9.2e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EEFEMGPG_03202 1.6e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EEFEMGPG_03203 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
EEFEMGPG_03204 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EEFEMGPG_03205 6.8e-12
EEFEMGPG_03206 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EEFEMGPG_03207 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EEFEMGPG_03208 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EEFEMGPG_03209 2.2e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EEFEMGPG_03210 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EEFEMGPG_03211 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EEFEMGPG_03212 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EEFEMGPG_03213 2.1e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
EEFEMGPG_03214 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_03215 8.4e-254 comP 2.7.13.3 T Histidine kinase
EEFEMGPG_03217 2e-62 comQ H Polyprenyl synthetase
EEFEMGPG_03219 8.9e-51 yuzC
EEFEMGPG_03220 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EEFEMGPG_03221 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EEFEMGPG_03222 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
EEFEMGPG_03223 7.2e-68 yueI S Protein of unknown function (DUF1694)
EEFEMGPG_03224 2.8e-38 yueH S YueH-like protein
EEFEMGPG_03225 6.4e-34 yueG S Spore germination protein gerPA/gerPF
EEFEMGPG_03226 1.9e-187 yueF S transporter activity
EEFEMGPG_03227 1.6e-22 S Protein of unknown function (DUF2642)
EEFEMGPG_03228 3.7e-96 yueE S phosphohydrolase
EEFEMGPG_03229 3e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_03230 6.6e-76 yueC S Family of unknown function (DUF5383)
EEFEMGPG_03231 0.0 esaA S type VII secretion protein EsaA
EEFEMGPG_03232 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EEFEMGPG_03233 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
EEFEMGPG_03234 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
EEFEMGPG_03235 2.8e-45 esxA S Belongs to the WXG100 family
EEFEMGPG_03236 1.5e-228 yukF QT Transcriptional regulator
EEFEMGPG_03237 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EEFEMGPG_03238 2.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
EEFEMGPG_03239 1.3e-34 mbtH S MbtH-like protein
EEFEMGPG_03240 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_03241 2.9e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EEFEMGPG_03242 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EEFEMGPG_03243 8.1e-224 entC 5.4.4.2 HQ Isochorismate synthase
EEFEMGPG_03244 1e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03245 6.2e-165 besA S Putative esterase
EEFEMGPG_03246 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
EEFEMGPG_03247 1.1e-101 bioY S Biotin biosynthesis protein
EEFEMGPG_03248 6.2e-209 yuiF S antiporter
EEFEMGPG_03249 5.8e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EEFEMGPG_03250 1.2e-77 yuiD S protein conserved in bacteria
EEFEMGPG_03251 4.2e-115 yuiC S protein conserved in bacteria
EEFEMGPG_03252 9.9e-28 yuiB S Putative membrane protein
EEFEMGPG_03253 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
EEFEMGPG_03254 1.1e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
EEFEMGPG_03256 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EEFEMGPG_03257 4.8e-29
EEFEMGPG_03258 1.2e-70 CP Membrane
EEFEMGPG_03259 1.1e-122 V ABC transporter
EEFEMGPG_03261 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
EEFEMGPG_03263 1.6e-37 rimJ 2.3.1.128 J Alanine acetyltransferase
EEFEMGPG_03264 7.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03265 1.1e-62 erpA S Belongs to the HesB IscA family
EEFEMGPG_03266 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EEFEMGPG_03267 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEFEMGPG_03268 2.4e-39 yuzB S Belongs to the UPF0349 family
EEFEMGPG_03269 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
EEFEMGPG_03270 6.7e-56 yuzD S protein conserved in bacteria
EEFEMGPG_03271 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EEFEMGPG_03272 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EEFEMGPG_03273 2e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EEFEMGPG_03274 5.7e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EEFEMGPG_03275 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
EEFEMGPG_03276 3.2e-197 yutH S Spore coat protein
EEFEMGPG_03277 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EEFEMGPG_03278 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EEFEMGPG_03279 1.6e-73 yutE S Protein of unknown function DUF86
EEFEMGPG_03280 1.7e-47 yutD S protein conserved in bacteria
EEFEMGPG_03281 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EEFEMGPG_03282 1.9e-194 lytH M Peptidase, M23
EEFEMGPG_03283 8.7e-131 yunB S Sporulation protein YunB (Spo_YunB)
EEFEMGPG_03284 1.3e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EEFEMGPG_03285 1.8e-145 yunE S membrane transporter protein
EEFEMGPG_03286 3.1e-169 yunF S Protein of unknown function DUF72
EEFEMGPG_03287 1.3e-60 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
EEFEMGPG_03288 2.6e-263 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EEFEMGPG_03289 2.3e-303 pucR QT COG2508 Regulator of polyketide synthase expression
EEFEMGPG_03292 3.8e-130 S Aspartate phosphatase response regulator
EEFEMGPG_03294 5.9e-67
EEFEMGPG_03295 1.7e-213 blt EGP Major facilitator Superfamily
EEFEMGPG_03296 1.1e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EEFEMGPG_03297 1.1e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EEFEMGPG_03298 4.1e-169 bsn L Ribonuclease
EEFEMGPG_03299 2.2e-207 msmX P Belongs to the ABC transporter superfamily
EEFEMGPG_03300 1.2e-134 yurK K UTRA
EEFEMGPG_03301 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EEFEMGPG_03302 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
EEFEMGPG_03303 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
EEFEMGPG_03304 2.3e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EEFEMGPG_03305 3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EEFEMGPG_03306 2.9e-165 K helix_turn_helix, mercury resistance
EEFEMGPG_03309 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EEFEMGPG_03310 6.2e-202 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EEFEMGPG_03311 2.7e-126 Q ubiE/COQ5 methyltransferase family
EEFEMGPG_03312 1e-81 yncE S Protein of unknown function (DUF2691)
EEFEMGPG_03313 2.5e-155 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EEFEMGPG_03314 3e-270 sufB O FeS cluster assembly
EEFEMGPG_03315 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EEFEMGPG_03316 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EEFEMGPG_03317 7e-245 sufD O assembly protein SufD
EEFEMGPG_03318 6.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EEFEMGPG_03319 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EEFEMGPG_03320 3e-145 metQ P Belongs to the NlpA lipoprotein family
EEFEMGPG_03321 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
EEFEMGPG_03322 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EEFEMGPG_03323 5e-57 yusD S SCP-2 sterol transfer family
EEFEMGPG_03324 1.6e-54 yusE CO Thioredoxin
EEFEMGPG_03325 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EEFEMGPG_03326 3.7e-40 yusG S Protein of unknown function (DUF2553)
EEFEMGPG_03327 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EEFEMGPG_03328 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
EEFEMGPG_03329 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EEFEMGPG_03330 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
EEFEMGPG_03331 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EEFEMGPG_03333 1.3e-165 fadM E Proline dehydrogenase
EEFEMGPG_03334 1.8e-210 yusP P Major facilitator superfamily
EEFEMGPG_03335 2e-42
EEFEMGPG_03336 1.1e-53 yusN M Coat F domain
EEFEMGPG_03337 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
EEFEMGPG_03338 8.1e-288 yusP P Major facilitator superfamily
EEFEMGPG_03339 3.2e-65 yusQ S Tautomerase enzyme
EEFEMGPG_03340 5.3e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03341 1.9e-158 yusT K LysR substrate binding domain
EEFEMGPG_03342 4.7e-160 ywbI2 K Transcriptional regulator
EEFEMGPG_03343 1.5e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EEFEMGPG_03344 2.8e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEFEMGPG_03345 3.6e-38 yusU S Protein of unknown function (DUF2573)
EEFEMGPG_03346 1.4e-150 yusV 3.6.3.34 HP ABC transporter
EEFEMGPG_03347 3.2e-45 S YusW-like protein
EEFEMGPG_03348 0.0 pepF2 E COG1164 Oligoendopeptidase F
EEFEMGPG_03349 1.4e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03350 1.6e-79 dps P Belongs to the Dps family
EEFEMGPG_03351 4.8e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEFEMGPG_03352 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_03353 1.5e-250 cssS 2.7.13.3 T PhoQ Sensor
EEFEMGPG_03354 3.4e-24
EEFEMGPG_03355 5.9e-158 yuxN K Transcriptional regulator
EEFEMGPG_03356 5.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EEFEMGPG_03357 6.6e-24 S Protein of unknown function (DUF3970)
EEFEMGPG_03358 2.4e-259 gerAA EG Spore germination protein
EEFEMGPG_03359 2e-184 gerAB E Spore germination protein
EEFEMGPG_03360 9.6e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
EEFEMGPG_03361 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_03362 2.3e-193 vraS 2.7.13.3 T Histidine kinase
EEFEMGPG_03363 9.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EEFEMGPG_03364 7.6e-115 liaG S Putative adhesin
EEFEMGPG_03365 1.7e-93 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EEFEMGPG_03366 2.8e-45 liaI S membrane
EEFEMGPG_03367 1.1e-226 yvqJ EGP Major facilitator Superfamily
EEFEMGPG_03368 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
EEFEMGPG_03369 4.7e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EEFEMGPG_03370 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_03371 4.2e-167 yvrC P ABC transporter substrate-binding protein
EEFEMGPG_03372 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03373 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
EEFEMGPG_03374 0.0 T PhoQ Sensor
EEFEMGPG_03375 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_03376 1.1e-36
EEFEMGPG_03377 9.9e-103 yvrI K RNA polymerase
EEFEMGPG_03378 1.6e-15 S YvrJ protein family
EEFEMGPG_03379 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
EEFEMGPG_03380 1.4e-66 yvrL S Regulatory protein YrvL
EEFEMGPG_03381 1.8e-147 fhuC 3.6.3.34 HP ABC transporter
EEFEMGPG_03382 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_03383 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_03384 4e-178 fhuD P ABC transporter
EEFEMGPG_03385 4.5e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EEFEMGPG_03386 2.9e-236 yvsH E Arginine ornithine antiporter
EEFEMGPG_03387 3.6e-14 S Small spore protein J (Spore_SspJ)
EEFEMGPG_03388 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EEFEMGPG_03389 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EEFEMGPG_03390 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EEFEMGPG_03391 4.1e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EEFEMGPG_03392 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
EEFEMGPG_03393 3.7e-114 yfiK K Regulator
EEFEMGPG_03394 2.5e-179 T Histidine kinase
EEFEMGPG_03395 3.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
EEFEMGPG_03396 2.3e-193 yfiM V ABC-2 type transporter
EEFEMGPG_03397 8.9e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
EEFEMGPG_03398 5e-156 yvgN S reductase
EEFEMGPG_03399 3.2e-86 yvgO
EEFEMGPG_03400 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EEFEMGPG_03401 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EEFEMGPG_03402 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EEFEMGPG_03403 0.0 helD 3.6.4.12 L DNA helicase
EEFEMGPG_03404 3.1e-99 yvgT S membrane
EEFEMGPG_03405 1.5e-141 S Metallo-peptidase family M12
EEFEMGPG_03406 6e-73 bdbC O Required for disulfide bond formation in some proteins
EEFEMGPG_03407 7e-100 bdbD O Thioredoxin
EEFEMGPG_03408 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EEFEMGPG_03409 0.0 copA 3.6.3.54 P P-type ATPase
EEFEMGPG_03410 2.6e-29 copZ P Heavy-metal-associated domain
EEFEMGPG_03411 3.7e-48 csoR S transcriptional
EEFEMGPG_03412 3.5e-191 yvaA 1.1.1.371 S Oxidoreductase
EEFEMGPG_03413 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EEFEMGPG_03414 5.6e-163 K Helix-turn-helix XRE-family like proteins
EEFEMGPG_03415 7.2e-220 ynfM EGP Major Facilitator Superfamily
EEFEMGPG_03416 2.7e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
EEFEMGPG_03417 4.4e-146 S Amidohydrolase
EEFEMGPG_03418 1.2e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_03419 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
EEFEMGPG_03420 4.6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_03421 4.3e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EEFEMGPG_03422 3.8e-120 tcyM U Binding-protein-dependent transport system inner membrane component
EEFEMGPG_03423 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
EEFEMGPG_03424 1.2e-146 tcyK M Bacterial periplasmic substrate-binding proteins
EEFEMGPG_03425 3.5e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
EEFEMGPG_03426 3.3e-100 ytmI K Acetyltransferase (GNAT) domain
EEFEMGPG_03427 6.1e-160 ytlI K LysR substrate binding domain
EEFEMGPG_03428 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EEFEMGPG_03429 2.6e-49 yrdF K ribonuclease inhibitor
EEFEMGPG_03430 1.5e-38 yrdF K ribonuclease inhibitor
EEFEMGPG_03432 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EEFEMGPG_03433 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EEFEMGPG_03434 7.4e-143 est 3.1.1.1 S Carboxylesterase
EEFEMGPG_03435 4.8e-24 secG U Preprotein translocase subunit SecG
EEFEMGPG_03436 6e-35 yvzC K Transcriptional
EEFEMGPG_03437 1e-69 K transcriptional
EEFEMGPG_03438 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
EEFEMGPG_03439 8.8e-53 yodB K transcriptional
EEFEMGPG_03440 2e-258 T His Kinase A (phosphoacceptor) domain
EEFEMGPG_03441 2e-123 K Transcriptional regulatory protein, C terminal
EEFEMGPG_03442 3.1e-136 mutG S ABC-2 family transporter protein
EEFEMGPG_03443 2.9e-123 spaE S ABC-2 family transporter protein
EEFEMGPG_03444 9.3e-127 mutF V ABC transporter, ATP-binding protein
EEFEMGPG_03445 4.7e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EEFEMGPG_03446 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EEFEMGPG_03447 7.8e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EEFEMGPG_03448 4.9e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EEFEMGPG_03449 2.4e-62 yvbF K Belongs to the GbsR family
EEFEMGPG_03450 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EEFEMGPG_03451 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EEFEMGPG_03452 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EEFEMGPG_03453 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EEFEMGPG_03454 7.1e-98 yvbF K Belongs to the GbsR family
EEFEMGPG_03455 1.5e-104 yvbG U UPF0056 membrane protein
EEFEMGPG_03456 7.6e-121 exoY M Membrane
EEFEMGPG_03457 0.0 tcaA S response to antibiotic
EEFEMGPG_03458 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
EEFEMGPG_03459 5.1e-213 EGP Major facilitator Superfamily
EEFEMGPG_03460 4.7e-179
EEFEMGPG_03461 3.7e-125 S GlcNAc-PI de-N-acetylase
EEFEMGPG_03462 9.6e-143 C WbqC-like protein family
EEFEMGPG_03463 1.2e-150 M Protein involved in cellulose biosynthesis
EEFEMGPG_03464 6.2e-235 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EEFEMGPG_03465 2.3e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
EEFEMGPG_03466 1.3e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EEFEMGPG_03467 5.2e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EEFEMGPG_03468 2.1e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EEFEMGPG_03469 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EEFEMGPG_03470 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EEFEMGPG_03471 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EEFEMGPG_03472 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EEFEMGPG_03473 3.1e-184 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EEFEMGPG_03474 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EEFEMGPG_03476 7.4e-253 araE EGP Major facilitator Superfamily
EEFEMGPG_03477 7.6e-205 araR K transcriptional
EEFEMGPG_03478 9.3e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_03480 1.4e-156 yvbU K Transcriptional regulator
EEFEMGPG_03481 7.7e-158 yvbV EG EamA-like transporter family
EEFEMGPG_03482 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_03483 9e-261
EEFEMGPG_03484 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
EEFEMGPG_03485 1.2e-115 yyaS S Membrane
EEFEMGPG_03486 2.3e-167 3.1.3.104 S hydrolases of the HAD superfamily
EEFEMGPG_03487 5e-151 ybbH_1 K RpiR family transcriptional regulator
EEFEMGPG_03488 4.1e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
EEFEMGPG_03489 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
EEFEMGPG_03490 1.4e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EEFEMGPG_03491 4.7e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EEFEMGPG_03492 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EEFEMGPG_03493 6.1e-224 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EEFEMGPG_03494 1.3e-120 yvfI K COG2186 Transcriptional regulators
EEFEMGPG_03495 3.2e-303 yvfH C L-lactate permease
EEFEMGPG_03496 1.7e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EEFEMGPG_03497 2.7e-32 yvfG S YvfG protein
EEFEMGPG_03498 7.5e-188 yvfF GM Exopolysaccharide biosynthesis protein
EEFEMGPG_03499 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EEFEMGPG_03500 5.6e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EEFEMGPG_03501 7e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EEFEMGPG_03502 8.2e-274 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_03503 3.6e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EEFEMGPG_03504 7.1e-203 epsI GM pyruvyl transferase
EEFEMGPG_03505 3.1e-195 epsH GT2 S Glycosyltransferase like family 2
EEFEMGPG_03506 3.5e-205 epsG S EpsG family
EEFEMGPG_03507 4.2e-214 epsF GT4 M Glycosyl transferases group 1
EEFEMGPG_03508 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EEFEMGPG_03509 6.3e-218 epsD GT4 M Glycosyl transferase 4-like
EEFEMGPG_03510 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EEFEMGPG_03511 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EEFEMGPG_03512 8.4e-120 ywqC M biosynthesis protein
EEFEMGPG_03513 1.9e-77 slr K transcriptional
EEFEMGPG_03514 6.4e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EEFEMGPG_03515 6.8e-98 ywjB H RibD C-terminal domain
EEFEMGPG_03516 3.7e-111 yyaS S Membrane
EEFEMGPG_03517 1.9e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EEFEMGPG_03518 5.5e-94 padC Q Phenolic acid decarboxylase
EEFEMGPG_03519 9.2e-13 S Protein of unknown function (DUF1433)
EEFEMGPG_03520 7.1e-25 S Protein of unknown function (DUF1433)
EEFEMGPG_03521 7.7e-18 S Protein of unknown function (DUF1433)
EEFEMGPG_03522 1.8e-16 S Protein of unknown function (DUF1433)
EEFEMGPG_03523 7e-267 I Pfam Lipase (class 3)
EEFEMGPG_03524 3.5e-46
EEFEMGPG_03525 2.1e-93 yybG S Pentapeptide repeats (8 copies)
EEFEMGPG_03526 2e-62 L Phage integrase family
EEFEMGPG_03528 1.8e-297 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
EEFEMGPG_03529 3.6e-219 rafB P LacY proton/sugar symporter
EEFEMGPG_03530 3.3e-183 scrR K transcriptional
EEFEMGPG_03531 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EEFEMGPG_03532 6.7e-164 yraN K Transcriptional regulator
EEFEMGPG_03533 4.9e-215 yraM S PrpF protein
EEFEMGPG_03534 7.5e-250 EGP Sugar (and other) transporter
EEFEMGPG_03535 2.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
EEFEMGPG_03536 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
EEFEMGPG_03537 5.6e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EEFEMGPG_03538 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EEFEMGPG_03539 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEFEMGPG_03540 1.6e-79 M Ribonuclease
EEFEMGPG_03541 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EEFEMGPG_03542 4.7e-36 crh G Phosphocarrier protein Chr
EEFEMGPG_03543 3.1e-170 whiA K May be required for sporulation
EEFEMGPG_03544 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EEFEMGPG_03545 1.1e-166 rapZ S Displays ATPase and GTPase activities
EEFEMGPG_03546 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EEFEMGPG_03547 5.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EEFEMGPG_03548 4.5e-125 usp CBM50 M protein conserved in bacteria
EEFEMGPG_03549 3.2e-275 S COG0457 FOG TPR repeat
EEFEMGPG_03550 3.2e-192 sasA T Histidine kinase
EEFEMGPG_03551 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_03552 0.0 msbA2 3.6.3.44 V ABC transporter
EEFEMGPG_03553 6.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EEFEMGPG_03554 6.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EEFEMGPG_03555 3.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EEFEMGPG_03556 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EEFEMGPG_03557 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EEFEMGPG_03558 3.8e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EEFEMGPG_03559 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EEFEMGPG_03560 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EEFEMGPG_03561 9.1e-138 yvpB NU protein conserved in bacteria
EEFEMGPG_03562 4.4e-72 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EEFEMGPG_03563 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EEFEMGPG_03564 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EEFEMGPG_03565 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EEFEMGPG_03566 1.2e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EEFEMGPG_03567 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EEFEMGPG_03568 1.3e-131 yvoA K transcriptional
EEFEMGPG_03569 3.1e-104 yxaF K Transcriptional regulator
EEFEMGPG_03570 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EEFEMGPG_03571 3.9e-41 yvlD S Membrane
EEFEMGPG_03572 9.6e-26 pspB KT PspC domain
EEFEMGPG_03573 9.2e-166 yvlB S Putative adhesin
EEFEMGPG_03574 6.1e-49 yvlA
EEFEMGPG_03575 3e-38 yvkN
EEFEMGPG_03576 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EEFEMGPG_03577 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EEFEMGPG_03578 7.6e-33 csbA S protein conserved in bacteria
EEFEMGPG_03579 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EEFEMGPG_03580 2.4e-110 yvkB K Transcriptional regulator
EEFEMGPG_03581 3e-227 yvkA EGP Major facilitator Superfamily
EEFEMGPG_03582 1.1e-174 S Psort location CytoplasmicMembrane, score
EEFEMGPG_03583 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEFEMGPG_03584 1.5e-55 swrA S Swarming motility protein
EEFEMGPG_03585 8.7e-254 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EEFEMGPG_03586 9.8e-221 ywoF P Right handed beta helix region
EEFEMGPG_03587 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EEFEMGPG_03588 1e-122 ftsE D cell division ATP-binding protein FtsE
EEFEMGPG_03589 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
EEFEMGPG_03590 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_03591 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EEFEMGPG_03592 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EEFEMGPG_03593 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EEFEMGPG_03594 6.8e-68
EEFEMGPG_03595 4.5e-10 fliT S bacterial-type flagellum organization
EEFEMGPG_03596 3e-66 fliS N flagellar protein FliS
EEFEMGPG_03597 1.8e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EEFEMGPG_03598 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEFEMGPG_03599 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EEFEMGPG_03600 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EEFEMGPG_03601 1.4e-80 yviE
EEFEMGPG_03602 6.1e-163 flgL N Belongs to the bacterial flagellin family
EEFEMGPG_03603 1.1e-273 flgK N flagellar hook-associated protein
EEFEMGPG_03604 8.9e-81 flgN NOU FlgN protein
EEFEMGPG_03605 1.4e-38 flgM KNU Negative regulator of flagellin synthesis
EEFEMGPG_03606 2.4e-74 yvyF S flagellar protein
EEFEMGPG_03607 4.5e-77 comFC S Phosphoribosyl transferase domain
EEFEMGPG_03608 1.5e-43 comFB S Late competence development protein ComFB
EEFEMGPG_03609 3.6e-260 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EEFEMGPG_03610 1.6e-157 degV S protein conserved in bacteria
EEFEMGPG_03611 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_03612 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EEFEMGPG_03613 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EEFEMGPG_03614 2.1e-166 yvhJ K Transcriptional regulator
EEFEMGPG_03615 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EEFEMGPG_03616 4e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EEFEMGPG_03617 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
EEFEMGPG_03618 3.5e-115 tuaF M protein involved in exopolysaccharide biosynthesis
EEFEMGPG_03619 2.9e-257 tuaE M Teichuronic acid biosynthesis protein
EEFEMGPG_03620 7.3e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EEFEMGPG_03621 2.8e-224 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EEFEMGPG_03622 1.9e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EEFEMGPG_03623 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EEFEMGPG_03624 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EEFEMGPG_03625 3e-306 lytB 3.5.1.28 D Stage II sporulation protein
EEFEMGPG_03626 4.5e-30
EEFEMGPG_03627 1.5e-137 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EEFEMGPG_03628 3.5e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EEFEMGPG_03629 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EEFEMGPG_03630 3.2e-180 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EEFEMGPG_03631 9.8e-136 tagG GM Transport permease protein
EEFEMGPG_03632 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EEFEMGPG_03633 1.7e-245 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
EEFEMGPG_03634 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EEFEMGPG_03635 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EEFEMGPG_03636 8.5e-210 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EEFEMGPG_03637 2.6e-129 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EEFEMGPG_03638 1.8e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EEFEMGPG_03639 2.3e-265 gerBA EG Spore germination protein
EEFEMGPG_03640 1.4e-198 gerBB E Spore germination protein
EEFEMGPG_03641 2.3e-212 gerAC S Spore germination protein
EEFEMGPG_03642 7.5e-266 GT2,GT4 J Glycosyl transferase family 2
EEFEMGPG_03643 4.1e-248 ywtG EGP Major facilitator Superfamily
EEFEMGPG_03644 3.2e-178 ywtF K Transcriptional regulator
EEFEMGPG_03645 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EEFEMGPG_03646 2.6e-36 yttA 2.7.13.3 S Pfam Transposase IS66
EEFEMGPG_03647 9.8e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EEFEMGPG_03648 1.3e-20 ywtC
EEFEMGPG_03649 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EEFEMGPG_03650 2.3e-70 pgsC S biosynthesis protein
EEFEMGPG_03651 1.1e-222 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EEFEMGPG_03652 7.7e-184 gerKA EG Spore germination protein
EEFEMGPG_03653 3.7e-191 gerKB E Spore germination protein
EEFEMGPG_03654 4.7e-205 gerKC S Spore germination B3/ GerAC like, C-terminal
EEFEMGPG_03655 5e-179 rbsR K transcriptional
EEFEMGPG_03656 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEFEMGPG_03657 4.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EEFEMGPG_03658 1.3e-279 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EEFEMGPG_03659 3.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
EEFEMGPG_03660 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EEFEMGPG_03661 1.5e-89 batE T Sh3 type 3 domain protein
EEFEMGPG_03662 6.3e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EEFEMGPG_03663 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EEFEMGPG_03664 2.6e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EEFEMGPG_03665 3.4e-166 alsR K LysR substrate binding domain
EEFEMGPG_03666 8.1e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EEFEMGPG_03667 4.4e-126 ywrJ
EEFEMGPG_03668 1.9e-129 cotB
EEFEMGPG_03669 8.5e-212 cotH M Spore Coat
EEFEMGPG_03670 4.5e-09
EEFEMGPG_03671 2.8e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EEFEMGPG_03672 4.7e-07 S Domain of unknown function (DUF4181)
EEFEMGPG_03673 9.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EEFEMGPG_03674 1.1e-83 ywrC K Transcriptional regulator
EEFEMGPG_03675 1.2e-103 ywrB P Chromate transporter
EEFEMGPG_03676 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
EEFEMGPG_03677 4.2e-135 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EEFEMGPG_03678 6.2e-93
EEFEMGPG_03679 3.3e-74 S SMI1 / KNR4 family
EEFEMGPG_03680 1e-64 S SMI1 / KNR4 family (SUKH-1)
EEFEMGPG_03681 4.2e-239 ywqJ S Pre-toxin TG
EEFEMGPG_03682 4.3e-37 ywqI S Family of unknown function (DUF5344)
EEFEMGPG_03683 1.1e-21 S Domain of unknown function (DUF5082)
EEFEMGPG_03685 1.7e-150 ywqG S Domain of unknown function (DUF1963)
EEFEMGPG_03686 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EEFEMGPG_03687 1.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EEFEMGPG_03688 2.1e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EEFEMGPG_03689 6.8e-112 ywqC M biosynthesis protein
EEFEMGPG_03690 1.3e-14
EEFEMGPG_03691 1.6e-307 ywqB S SWIM zinc finger
EEFEMGPG_03692 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EEFEMGPG_03693 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EEFEMGPG_03694 1.7e-134 glcR K DeoR C terminal sensor domain
EEFEMGPG_03695 7.5e-58 ssbB L Single-stranded DNA-binding protein
EEFEMGPG_03696 4e-62 ywpG
EEFEMGPG_03697 3.9e-69 ywpF S YwpF-like protein
EEFEMGPG_03698 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EEFEMGPG_03699 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EEFEMGPG_03700 1e-198 S aspartate phosphatase
EEFEMGPG_03701 6.1e-146 flhP N flagellar basal body
EEFEMGPG_03702 3.2e-128 flhO N flagellar basal body
EEFEMGPG_03703 2.7e-180 mbl D Rod shape-determining protein
EEFEMGPG_03704 1.8e-44 spoIIID K Stage III sporulation protein D
EEFEMGPG_03705 8.5e-72 ywoH K transcriptional
EEFEMGPG_03706 3.8e-213 ywoG EGP Major facilitator Superfamily
EEFEMGPG_03707 4.2e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EEFEMGPG_03708 5.2e-243 ywoD EGP Major facilitator superfamily
EEFEMGPG_03709 7e-101 phzA Q Isochorismatase family
EEFEMGPG_03710 2.5e-228 amt P Ammonium transporter
EEFEMGPG_03711 2e-58 nrgB K Belongs to the P(II) protein family
EEFEMGPG_03712 2.4e-209 ftsW D Belongs to the SEDS family
EEFEMGPG_03713 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EEFEMGPG_03714 5.1e-72 ywnJ S VanZ like family
EEFEMGPG_03715 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EEFEMGPG_03716 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EEFEMGPG_03717 1.2e-10 ywnC S Family of unknown function (DUF5362)
EEFEMGPG_03718 1.6e-68 ywnF S Family of unknown function (DUF5392)
EEFEMGPG_03719 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEFEMGPG_03720 1.7e-53 ywnC S Family of unknown function (DUF5362)
EEFEMGPG_03721 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EEFEMGPG_03722 6.1e-67 ywnA K Transcriptional regulator
EEFEMGPG_03723 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EEFEMGPG_03724 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EEFEMGPG_03725 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EEFEMGPG_03727 8e-82 ywmF S Peptidase M50
EEFEMGPG_03728 1.6e-93 S response regulator aspartate phosphatase
EEFEMGPG_03729 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EEFEMGPG_03730 5.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EEFEMGPG_03732 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EEFEMGPG_03733 1.6e-115 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EEFEMGPG_03734 1.4e-187 spoIID D Stage II sporulation protein D
EEFEMGPG_03735 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EEFEMGPG_03736 9.7e-135 ywmB S TATA-box binding
EEFEMGPG_03737 2.1e-32 ywzB S membrane
EEFEMGPG_03738 1.2e-90 ywmA
EEFEMGPG_03739 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EEFEMGPG_03740 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EEFEMGPG_03741 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EEFEMGPG_03742 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EEFEMGPG_03743 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EEFEMGPG_03744 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EEFEMGPG_03745 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EEFEMGPG_03746 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
EEFEMGPG_03747 2.1e-61 atpI S ATP synthase
EEFEMGPG_03748 5.2e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EEFEMGPG_03749 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EEFEMGPG_03750 5.9e-97 ywlG S Belongs to the UPF0340 family
EEFEMGPG_03751 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EEFEMGPG_03752 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EEFEMGPG_03753 1.2e-84 mntP P Probably functions as a manganese efflux pump
EEFEMGPG_03754 2.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EEFEMGPG_03755 1.1e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EEFEMGPG_03756 8.9e-119 spoIIR S stage II sporulation protein R
EEFEMGPG_03757 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
EEFEMGPG_03759 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EEFEMGPG_03760 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EEFEMGPG_03761 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EEFEMGPG_03762 1.5e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EEFEMGPG_03763 1e-157 ywkB S Membrane transport protein
EEFEMGPG_03764 0.0 sfcA 1.1.1.38 C malic enzyme
EEFEMGPG_03765 1.4e-104 tdk 2.7.1.21 F thymidine kinase
EEFEMGPG_03766 1.1e-32 rpmE J Binds the 23S rRNA
EEFEMGPG_03767 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EEFEMGPG_03768 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EEFEMGPG_03769 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EEFEMGPG_03770 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EEFEMGPG_03771 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EEFEMGPG_03772 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
EEFEMGPG_03773 4.2e-92 ywjG S Domain of unknown function (DUF2529)
EEFEMGPG_03774 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EEFEMGPG_03775 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EEFEMGPG_03776 0.0 fadF C COG0247 Fe-S oxidoreductase
EEFEMGPG_03777 4.6e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EEFEMGPG_03778 8.9e-181 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EEFEMGPG_03779 4.2e-43 ywjC
EEFEMGPG_03780 0.0 ywjA V ABC transporter
EEFEMGPG_03781 3.4e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEFEMGPG_03782 2e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EEFEMGPG_03783 7e-124 narI 1.7.5.1 C nitrate reductase, gamma
EEFEMGPG_03784 7.9e-97 narJ 1.7.5.1 C nitrate reductase
EEFEMGPG_03785 5.3e-294 narH 1.7.5.1 C Nitrate reductase, beta
EEFEMGPG_03786 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEFEMGPG_03787 2e-85 arfM T cyclic nucleotide binding
EEFEMGPG_03788 2.8e-139 ywiC S YwiC-like protein
EEFEMGPG_03789 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
EEFEMGPG_03790 5.8e-214 narK P COG2223 Nitrate nitrite transporter
EEFEMGPG_03791 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EEFEMGPG_03792 1.2e-73 ywiB S protein conserved in bacteria
EEFEMGPG_03794 2.5e-229 ywhL CO amine dehydrogenase activity
EEFEMGPG_03795 8e-204 ywhK CO amine dehydrogenase activity
EEFEMGPG_03796 6.4e-77 S aspartate phosphatase
EEFEMGPG_03798 2.6e-29 ydcG K sequence-specific DNA binding
EEFEMGPG_03799 5e-33
EEFEMGPG_03800 2e-28 S Domain of unknown function (DUF4177)
EEFEMGPG_03802 6.2e-77 CP Membrane
EEFEMGPG_03805 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
EEFEMGPG_03806 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EEFEMGPG_03807 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EEFEMGPG_03808 2e-79
EEFEMGPG_03809 1.4e-95 ywhD S YwhD family
EEFEMGPG_03810 1.2e-117 ywhC S Peptidase family M50
EEFEMGPG_03811 2.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EEFEMGPG_03812 5.2e-69 ywhA K Transcriptional regulator
EEFEMGPG_03813 3.9e-246 yhdG_1 E C-terminus of AA_permease
EEFEMGPG_03814 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
EEFEMGPG_03815 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
EEFEMGPG_03816 6.9e-36 ywzC S Belongs to the UPF0741 family
EEFEMGPG_03817 3e-110 rsfA_1
EEFEMGPG_03818 4.8e-51 padR K PadR family transcriptional regulator
EEFEMGPG_03819 1.1e-93 S membrane
EEFEMGPG_03820 1.3e-165 V ABC transporter, ATP-binding protein
EEFEMGPG_03821 1.3e-168 yhcI S ABC transporter (permease)
EEFEMGPG_03824 1.8e-186
EEFEMGPG_03826 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EEFEMGPG_03827 6e-163 cysL K Transcriptional regulator
EEFEMGPG_03828 1.8e-157 MA20_14895 S Conserved hypothetical protein 698
EEFEMGPG_03829 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EEFEMGPG_03830 1.1e-146 ywfI C May function as heme-dependent peroxidase
EEFEMGPG_03831 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
EEFEMGPG_03832 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
EEFEMGPG_03833 4.7e-208 bacE EGP Major facilitator Superfamily
EEFEMGPG_03834 4.4e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EEFEMGPG_03835 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EEFEMGPG_03836 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EEFEMGPG_03837 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EEFEMGPG_03838 2.4e-223 ywfA EGP Major facilitator Superfamily
EEFEMGPG_03839 1.7e-205 tcaB EGP Major facilitator Superfamily
EEFEMGPG_03840 8.3e-260 lysP E amino acid
EEFEMGPG_03841 0.0 rocB E arginine degradation protein
EEFEMGPG_03842 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EEFEMGPG_03843 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EEFEMGPG_03844 3.2e-59
EEFEMGPG_03845 3.5e-87 spsL 5.1.3.13 M Spore Coat
EEFEMGPG_03846 1.3e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EEFEMGPG_03847 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EEFEMGPG_03848 4.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EEFEMGPG_03849 6.8e-184 spsG M Spore Coat
EEFEMGPG_03850 1.5e-132 spsF M Spore Coat
EEFEMGPG_03851 1.2e-213 spsE 2.5.1.56 M acid synthase
EEFEMGPG_03852 9.5e-158 spsD 2.3.1.210 K Spore Coat
EEFEMGPG_03853 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
EEFEMGPG_03854 5.7e-277 spsB M Capsule polysaccharide biosynthesis protein
EEFEMGPG_03855 2.6e-143 spsA M Spore Coat
EEFEMGPG_03856 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EEFEMGPG_03857 4.2e-46 ywdK S small membrane protein
EEFEMGPG_03858 7.5e-231 ywdJ F Xanthine uracil
EEFEMGPG_03859 5.7e-39 ywdI S Family of unknown function (DUF5327)
EEFEMGPG_03860 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EEFEMGPG_03861 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
EEFEMGPG_03863 4.5e-88 ywdD
EEFEMGPG_03864 3.1e-56 pex K Transcriptional regulator PadR-like family
EEFEMGPG_03865 1.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EEFEMGPG_03866 9.7e-20 ywdA
EEFEMGPG_03867 1.4e-286 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
EEFEMGPG_03868 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_03869 4.4e-07 sacT K transcriptional antiterminator
EEFEMGPG_03870 1.8e-150 sacT K transcriptional antiterminator
EEFEMGPG_03872 0.0 vpr O Belongs to the peptidase S8 family
EEFEMGPG_03873 2.3e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEFEMGPG_03874 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EEFEMGPG_03875 2.9e-213 rodA D Belongs to the SEDS family
EEFEMGPG_03876 7e-79 ysnE K acetyltransferase
EEFEMGPG_03877 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
EEFEMGPG_03878 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EEFEMGPG_03879 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EEFEMGPG_03880 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EEFEMGPG_03881 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EEFEMGPG_03882 5.5e-26 ywzA S membrane
EEFEMGPG_03883 1.2e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EEFEMGPG_03884 1.1e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EEFEMGPG_03885 2.7e-62 gtcA S GtrA-like protein
EEFEMGPG_03886 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
EEFEMGPG_03888 5.6e-129 H Methionine biosynthesis protein MetW
EEFEMGPG_03889 1.7e-133 S Streptomycin biosynthesis protein StrF
EEFEMGPG_03890 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EEFEMGPG_03891 5.3e-242 ywbN P Dyp-type peroxidase family protein
EEFEMGPG_03892 6.6e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EEFEMGPG_03893 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EEFEMGPG_03894 8.2e-152 ywbI K Transcriptional regulator
EEFEMGPG_03895 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EEFEMGPG_03896 1.5e-110 ywbG M effector of murein hydrolase
EEFEMGPG_03897 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
EEFEMGPG_03898 4.6e-140 mta K transcriptional
EEFEMGPG_03899 1.6e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
EEFEMGPG_03900 3.6e-224 ywbD 2.1.1.191 J Methyltransferase
EEFEMGPG_03901 7.6e-67 ywbC 4.4.1.5 E glyoxalase
EEFEMGPG_03902 3.2e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EEFEMGPG_03903 2.2e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
EEFEMGPG_03904 9.7e-163 gspA M General stress
EEFEMGPG_03905 6.6e-116 ywaC 2.7.6.5 S protein conserved in bacteria
EEFEMGPG_03906 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EEFEMGPG_03907 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
EEFEMGPG_03908 2.1e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_03909 3.7e-229 dltB M membrane protein involved in D-alanine export
EEFEMGPG_03910 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EEFEMGPG_03911 6.3e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EEFEMGPG_03912 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EEFEMGPG_03913 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EEFEMGPG_03914 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EEFEMGPG_03915 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EEFEMGPG_03916 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EEFEMGPG_03917 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EEFEMGPG_03919 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EEFEMGPG_03920 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_03921 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEFEMGPG_03922 3e-167 cbrA3 P Periplasmic binding protein
EEFEMGPG_03923 1.4e-59 arsR K transcriptional
EEFEMGPG_03924 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EEFEMGPG_03925 2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EEFEMGPG_03926 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EEFEMGPG_03927 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EEFEMGPG_03928 1e-286 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EEFEMGPG_03929 1.6e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EEFEMGPG_03930 1.1e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
EEFEMGPG_03931 1.2e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EEFEMGPG_03932 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EEFEMGPG_03933 1.9e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EEFEMGPG_03934 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EEFEMGPG_03935 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EEFEMGPG_03936 1.5e-292 cydD V ATP-binding protein
EEFEMGPG_03937 4.7e-311 cydD V ATP-binding
EEFEMGPG_03938 1.9e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EEFEMGPG_03939 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
EEFEMGPG_03940 1.5e-215 cimH C COG3493 Na citrate symporter
EEFEMGPG_03941 7.1e-158 yxkH G Polysaccharide deacetylase
EEFEMGPG_03942 2.6e-205 msmK P Belongs to the ABC transporter superfamily
EEFEMGPG_03943 1e-167 lrp QT PucR C-terminal helix-turn-helix domain
EEFEMGPG_03944 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EEFEMGPG_03945 6.5e-87 yxkC S Domain of unknown function (DUF4352)
EEFEMGPG_03946 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EEFEMGPG_03947 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EEFEMGPG_03950 4.5e-77 yxjI S LURP-one-related
EEFEMGPG_03951 4.3e-219 yxjG 2.1.1.14 E Methionine synthase
EEFEMGPG_03952 1e-162 rlmA 2.1.1.187 Q Methyltransferase domain
EEFEMGPG_03953 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEFEMGPG_03954 2.7e-75 T Domain of unknown function (DUF4163)
EEFEMGPG_03955 1.4e-50 yxiS
EEFEMGPG_03956 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EEFEMGPG_03957 2.8e-222 citH C Citrate transporter
EEFEMGPG_03958 1.5e-143 exoK GH16 M licheninase activity
EEFEMGPG_03959 2.6e-149 licT K transcriptional antiterminator
EEFEMGPG_03960 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
EEFEMGPG_03961 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EEFEMGPG_03964 4.6e-61 S SMI1-KNR4 cell-wall
EEFEMGPG_03965 1.8e-78 yxiI S Protein of unknown function (DUF2716)
EEFEMGPG_03967 2.3e-21
EEFEMGPG_03968 1.1e-14 S YxiJ-like protein
EEFEMGPG_03970 1e-78
EEFEMGPG_03971 9.6e-33
EEFEMGPG_03974 2.6e-73 yxiG
EEFEMGPG_03975 6e-70 yxxG
EEFEMGPG_03978 3.1e-35
EEFEMGPG_03980 2.5e-52
EEFEMGPG_03981 0.0 wapA M COG3209 Rhs family protein
EEFEMGPG_03982 5e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
EEFEMGPG_03983 1.2e-147 yxxF EG EamA-like transporter family
EEFEMGPG_03984 9.8e-74 yxiE T Belongs to the universal stress protein A family
EEFEMGPG_03985 7.8e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EEFEMGPG_03986 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EEFEMGPG_03987 1.7e-53 S Protein of unknown function DUF262
EEFEMGPG_03988 2e-31 S FRG domain
EEFEMGPG_03989 4.3e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EEFEMGPG_03990 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EEFEMGPG_03991 6.2e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
EEFEMGPG_03992 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EEFEMGPG_03993 1.1e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EEFEMGPG_03994 2.2e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EEFEMGPG_03995 2e-253 lysP E amino acid
EEFEMGPG_03996 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EEFEMGPG_03997 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEFEMGPG_03998 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EEFEMGPG_03999 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EEFEMGPG_04000 4e-150 yidA S hydrolases of the HAD superfamily
EEFEMGPG_04003 6.4e-13 yxeE
EEFEMGPG_04004 3.2e-22 yxeD
EEFEMGPG_04005 6e-35
EEFEMGPG_04006 5.4e-178 fhuD P Periplasmic binding protein
EEFEMGPG_04007 1.3e-57 yxeA S Protein of unknown function (DUF1093)
EEFEMGPG_04008 0.0 yxdM V ABC transporter (permease)
EEFEMGPG_04009 5.5e-141 yxdL V ABC transporter, ATP-binding protein
EEFEMGPG_04010 1.6e-174 T PhoQ Sensor
EEFEMGPG_04011 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_04012 1.9e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EEFEMGPG_04013 1.3e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EEFEMGPG_04014 1.1e-166 iolH G Xylose isomerase-like TIM barrel
EEFEMGPG_04015 9.5e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EEFEMGPG_04016 1.8e-232 iolF EGP Major facilitator Superfamily
EEFEMGPG_04017 6.1e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EEFEMGPG_04018 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EEFEMGPG_04019 1.2e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EEFEMGPG_04020 5.8e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EEFEMGPG_04021 7.9e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EEFEMGPG_04022 5.8e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
EEFEMGPG_04023 4.9e-176 iolS C Aldo keto reductase
EEFEMGPG_04024 1.1e-40 L transposase activity
EEFEMGPG_04025 6.8e-134 L Molecular Function DNA binding, Biological Process DNA recombination
EEFEMGPG_04026 1.9e-245 csbC EGP Major facilitator Superfamily
EEFEMGPG_04027 0.0 htpG O Molecular chaperone. Has ATPase activity
EEFEMGPG_04029 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
EEFEMGPG_04030 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EEFEMGPG_04031 1e-199 desK 2.7.13.3 T Histidine kinase
EEFEMGPG_04032 9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EEFEMGPG_04033 6.4e-218 yxbF K Bacterial regulatory proteins, tetR family
EEFEMGPG_04034 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EEFEMGPG_04035 3.6e-142 S PQQ-like domain
EEFEMGPG_04036 1.7e-64 S Family of unknown function (DUF5391)
EEFEMGPG_04037 2.3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
EEFEMGPG_04038 1.7e-202 EGP Major facilitator Superfamily
EEFEMGPG_04039 2e-74 yxaI S membrane protein domain
EEFEMGPG_04040 1.5e-127 E Ring-cleavage extradiol dioxygenase
EEFEMGPG_04041 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EEFEMGPG_04042 2.3e-287 ahpF O Alkyl hydroperoxide reductase
EEFEMGPG_04043 2.7e-230 XK27_00240 S Fic/DOC family
EEFEMGPG_04044 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
EEFEMGPG_04045 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EEFEMGPG_04046 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EEFEMGPG_04047 3.9e-156 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EEFEMGPG_04048 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EEFEMGPG_04049 4.6e-90 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EEFEMGPG_04050 3.9e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EEFEMGPG_04051 1.4e-181 S Fusaric acid resistance protein-like
EEFEMGPG_04052 2.9e-20 O response to heat
EEFEMGPG_04053 1.2e-40 D nuclear chromosome segregation
EEFEMGPG_04057 0.0 L Recombinase
EEFEMGPG_04058 1.5e-10 spoIVCA L Recombinase
EEFEMGPG_04060 2.3e-232 S D5 N terminal like
EEFEMGPG_04065 4.3e-47
EEFEMGPG_04066 2.8e-68 radC L RadC-like JAB domain
EEFEMGPG_04067 2.1e-150 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EEFEMGPG_04068 1.5e-49 V HNH endonuclease
EEFEMGPG_04069 5.7e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EEFEMGPG_04070 7.9e-08 S YyzF-like protein
EEFEMGPG_04073 8.4e-218 yycP
EEFEMGPG_04074 5.9e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EEFEMGPG_04075 9.3e-186 C oxidoreductases (related to aryl-alcohol dehydrogenases)
EEFEMGPG_04076 8.1e-87 yycN 2.3.1.128 K Acetyltransferase
EEFEMGPG_04078 1.2e-200 S Histidine kinase
EEFEMGPG_04079 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EEFEMGPG_04080 1.2e-258 rocE E amino acid
EEFEMGPG_04081 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EEFEMGPG_04082 8.5e-63 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EEFEMGPG_04083 4.9e-42 sdpR K transcriptional
EEFEMGPG_04084 1.3e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EEFEMGPG_04085 7.7e-145 1.14.11.27 P peptidyl-arginine hydroxylation
EEFEMGPG_04086 5.7e-305 S ABC transporter
EEFEMGPG_04087 3.4e-198 S Major Facilitator Superfamily
EEFEMGPG_04088 8.5e-259
EEFEMGPG_04089 5.8e-191 2.7.7.73, 2.7.7.80 H ThiF family
EEFEMGPG_04090 1.2e-253 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
EEFEMGPG_04091 4.2e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_04092 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEFEMGPG_04093 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EEFEMGPG_04094 2.2e-151 yycI S protein conserved in bacteria
EEFEMGPG_04095 1.8e-259 yycH S protein conserved in bacteria
EEFEMGPG_04096 0.0 vicK 2.7.13.3 T Histidine kinase
EEFEMGPG_04097 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EEFEMGPG_04102 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EEFEMGPG_04103 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EEFEMGPG_04104 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EEFEMGPG_04105 1.4e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EEFEMGPG_04107 3.5e-17 yycC K YycC-like protein
EEFEMGPG_04108 1.6e-36 M 4-amino-4-deoxy-L-arabinose transferase activity
EEFEMGPG_04109 9.3e-242 M Glycosyltransferase Family 4
EEFEMGPG_04110 4.1e-203 S Ecdysteroid kinase
EEFEMGPG_04111 6.5e-234 S Carbamoyl-phosphate synthase L chain, ATP binding domain
EEFEMGPG_04112 9.3e-237 M Glycosyltransferase Family 4
EEFEMGPG_04113 1.9e-121 S GlcNAc-PI de-N-acetylase
EEFEMGPG_04114 1.8e-119 KLT COG0515 Serine threonine protein kinase
EEFEMGPG_04115 4.9e-73 rplI J binds to the 23S rRNA
EEFEMGPG_04116 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EEFEMGPG_04117 1.6e-158 yybS S membrane
EEFEMGPG_04119 6.5e-85 cotF M Spore coat protein
EEFEMGPG_04120 2.8e-66 ydeP3 K Transcriptional regulator
EEFEMGPG_04121 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EEFEMGPG_04122 1.8e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EEFEMGPG_04123 8.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
EEFEMGPG_04124 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EEFEMGPG_04125 1.2e-115 K FCD domain
EEFEMGPG_04126 1.8e-76 dinB S PFAM DinB family protein
EEFEMGPG_04127 7.6e-161 G Major Facilitator Superfamily
EEFEMGPG_04128 1.5e-158 yfiE K LysR substrate binding domain
EEFEMGPG_04129 1.1e-100 E LysE type translocator
EEFEMGPG_04130 1.3e-55 ypaA S Protein of unknown function (DUF1304)
EEFEMGPG_04131 5.6e-115 drgA C nitroreductase
EEFEMGPG_04132 3.2e-69 ydgJ K Winged helix DNA-binding domain
EEFEMGPG_04133 8.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EEFEMGPG_04134 2.5e-77 yybA 2.3.1.57 K transcriptional
EEFEMGPG_04135 5.9e-76 yjcF S Acetyltransferase (GNAT) domain
EEFEMGPG_04136 9.8e-163 eaeH M Domain of Unknown Function (DUF1259)
EEFEMGPG_04137 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
EEFEMGPG_04138 1.9e-164 K Transcriptional regulator
EEFEMGPG_04139 9.9e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EEFEMGPG_04140 4.3e-248 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EEFEMGPG_04141 4.7e-131 ydfC EG EamA-like transporter family
EEFEMGPG_04142 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EEFEMGPG_04143 1.2e-163 yyaK S CAAX protease self-immunity
EEFEMGPG_04144 6.2e-249 ydjK G Sugar (and other) transporter
EEFEMGPG_04145 5.8e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EEFEMGPG_04146 2.8e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EEFEMGPG_04147 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
EEFEMGPG_04148 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EEFEMGPG_04149 4.6e-108 adaA 3.2.2.21 K Transcriptional regulator
EEFEMGPG_04150 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EEFEMGPG_04151 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EEFEMGPG_04152 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EEFEMGPG_04153 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EEFEMGPG_04154 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEFEMGPG_04155 2.3e-33 yyzM S protein conserved in bacteria
EEFEMGPG_04156 2.4e-176 yyaD S Membrane
EEFEMGPG_04157 2.2e-82 4.2.1.103 K FR47-like protein
EEFEMGPG_04158 6.2e-111 yyaC S Sporulation protein YyaC
EEFEMGPG_04159 7.9e-149 spo0J K Belongs to the ParB family
EEFEMGPG_04160 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
EEFEMGPG_04161 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EEFEMGPG_04162 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EEFEMGPG_04163 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EEFEMGPG_04164 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EEFEMGPG_04165 1.4e-110 jag S single-stranded nucleic acid binding R3H
EEFEMGPG_04166 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EEFEMGPG_04167 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)