ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFDFGNCO_00002 6.8e-34
HFDFGNCO_00003 3e-59
HFDFGNCO_00004 0.0 topB 5.99.1.2 L DNA topoisomerase
HFDFGNCO_00005 1.2e-64
HFDFGNCO_00006 5e-64
HFDFGNCO_00007 3.9e-67
HFDFGNCO_00008 6.2e-182 S Fic/DOC family
HFDFGNCO_00009 1.6e-99 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HFDFGNCO_00012 7.3e-26
HFDFGNCO_00013 1.6e-145 fic D Fic/DOC family
HFDFGNCO_00014 5.1e-259 L Phage integrase family
HFDFGNCO_00015 3.7e-236 dinF V MatE
HFDFGNCO_00016 0.0 S LPXTG-motif cell wall anchor domain protein
HFDFGNCO_00017 2.3e-110 S Sucrose-6F-phosphate phosphohydrolase
HFDFGNCO_00019 5.1e-150 metQ P NLPA lipoprotein
HFDFGNCO_00020 2.5e-174 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFDFGNCO_00021 1.3e-93 metI P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00022 1.2e-211 S Peptidase dimerisation domain
HFDFGNCO_00023 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFDFGNCO_00024 4.5e-31
HFDFGNCO_00025 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HFDFGNCO_00026 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFDFGNCO_00027 2.9e-79 S Protein of unknown function (DUF3000)
HFDFGNCO_00028 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
HFDFGNCO_00029 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFDFGNCO_00030 2.7e-132 yebE S DUF218 domain
HFDFGNCO_00031 3.2e-127 E Psort location Cytoplasmic, score 8.87
HFDFGNCO_00032 2.3e-166 C Aldo/keto reductase family
HFDFGNCO_00033 1.4e-71 4.1.1.44 S Cupin domain
HFDFGNCO_00034 1.8e-41 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFDFGNCO_00035 2.3e-144 S phosphoesterase or phosphohydrolase
HFDFGNCO_00036 3e-212
HFDFGNCO_00037 1.7e-64
HFDFGNCO_00038 7.6e-09 XK26_04895
HFDFGNCO_00039 1.3e-18 L Transposase
HFDFGNCO_00040 5.7e-18 L Transposase
HFDFGNCO_00041 6.7e-31 L Transposase
HFDFGNCO_00042 2.2e-77 L protein secretion by the type IV secretion system
HFDFGNCO_00043 8.7e-114 S Putative inner membrane protein (DUF1819)
HFDFGNCO_00044 1.3e-125 S Domain of unknown function (DUF1788)
HFDFGNCO_00045 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HFDFGNCO_00046 0.0 LV DNA restriction-modification system
HFDFGNCO_00047 2.3e-72 S Domain of unknown function (DUF4263)
HFDFGNCO_00048 8.7e-255 lexA 3.6.4.12 K Putative DNA-binding domain
HFDFGNCO_00049 0.0 thiN 2.7.6.2 H PglZ domain
HFDFGNCO_00050 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
HFDFGNCO_00051 3.8e-191
HFDFGNCO_00053 0.0 S Protein of unknown function DUF262
HFDFGNCO_00054 9.9e-62 S Protein of unknown function DUF262
HFDFGNCO_00056 1.2e-123 3.2.1.8 S alpha beta
HFDFGNCO_00057 1.5e-83 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFDFGNCO_00058 3.7e-190 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFDFGNCO_00059 4.8e-113 kcsA U Ion channel
HFDFGNCO_00060 5.1e-39 pepC 3.4.22.40 E homocysteine catabolic process
HFDFGNCO_00061 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HFDFGNCO_00062 6.1e-109 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFDFGNCO_00063 0.0 ecfA GP ABC transporter, ATP-binding protein
HFDFGNCO_00064 2.4e-47 yhbY J CRS1_YhbY
HFDFGNCO_00065 4.8e-145 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFDFGNCO_00066 2.2e-201 S Glycosyltransferase, group 2 family protein
HFDFGNCO_00067 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HFDFGNCO_00068 8.1e-221 E Aminotransferase class I and II
HFDFGNCO_00069 5e-145 bioM P ATPases associated with a variety of cellular activities
HFDFGNCO_00070 0.0 2.8.2.22 S Arylsulfotransferase Ig-like domain
HFDFGNCO_00071 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFDFGNCO_00072 0.0 S Tetratricopeptide repeat
HFDFGNCO_00073 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFDFGNCO_00074 2.1e-205 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HFDFGNCO_00075 2.2e-84 ykoE S ABC-type cobalt transport system, permease component
HFDFGNCO_00076 2.3e-268 ykoD P ATPases associated with a variety of cellular activities
HFDFGNCO_00077 3.1e-145 cbiQ P Cobalt transport protein
HFDFGNCO_00078 1.6e-252 argE E Peptidase dimerisation domain
HFDFGNCO_00079 3.6e-93 S Protein of unknown function (DUF3043)
HFDFGNCO_00080 2.9e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFDFGNCO_00081 8.6e-142 S Domain of unknown function (DUF4191)
HFDFGNCO_00082 3.9e-281 glnA 6.3.1.2 E glutamine synthetase
HFDFGNCO_00083 4e-42 V DNA modification
HFDFGNCO_00084 6.4e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
HFDFGNCO_00085 1.5e-17 L HNH endonuclease
HFDFGNCO_00087 4.5e-18
HFDFGNCO_00088 1.3e-96 yvdD 3.2.2.10 S Possible lysine decarboxylase
HFDFGNCO_00089 1.5e-11 V FtsX-like permease family
HFDFGNCO_00090 1.1e-153 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFDFGNCO_00091 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFDFGNCO_00092 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HFDFGNCO_00093 4.9e-99
HFDFGNCO_00094 9.1e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFDFGNCO_00095 1.7e-210 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFDFGNCO_00096 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HFDFGNCO_00097 1.5e-239 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HFDFGNCO_00098 4.6e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFDFGNCO_00099 1.9e-84 argR K Regulates arginine biosynthesis genes
HFDFGNCO_00100 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFDFGNCO_00101 2.9e-279 argH 4.3.2.1 E argininosuccinate lyase
HFDFGNCO_00102 7e-92 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFDFGNCO_00103 8.6e-137 S Putative ABC-transporter type IV
HFDFGNCO_00104 0.0 S Protein of unknown function (DUF975)
HFDFGNCO_00105 1.3e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFDFGNCO_00106 1.5e-149 L Tetratricopeptide repeat
HFDFGNCO_00107 3.7e-193 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HFDFGNCO_00108 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFDFGNCO_00109 3e-116 trkA P TrkA-N domain
HFDFGNCO_00110 2.1e-266 trkB P Cation transport protein
HFDFGNCO_00111 2e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFDFGNCO_00112 3.7e-262 recN L May be involved in recombinational repair of damaged DNA
HFDFGNCO_00113 4.4e-123 S Haloacid dehalogenase-like hydrolase
HFDFGNCO_00114 7.4e-124 S ABC-2 family transporter protein
HFDFGNCO_00115 9.2e-175 V ATPases associated with a variety of cellular activities
HFDFGNCO_00116 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
HFDFGNCO_00117 4.3e-23 C Acetamidase/Formamidase family
HFDFGNCO_00118 3.2e-45 L transposition
HFDFGNCO_00119 0.0 S Histidine phosphatase superfamily (branch 2)
HFDFGNCO_00120 2.1e-94 S Pyridoxamine 5'-phosphate oxidase
HFDFGNCO_00121 1.8e-23 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00122 6.4e-96 bcp 1.11.1.15 O Redoxin
HFDFGNCO_00124 6.2e-55 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFDFGNCO_00125 5.3e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFDFGNCO_00126 9.1e-164 IQ Enoyl-(Acyl carrier protein) reductase
HFDFGNCO_00127 7.7e-145
HFDFGNCO_00128 7.4e-174 G Fic/DOC family
HFDFGNCO_00129 3.9e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
HFDFGNCO_00130 2.3e-232 EGP Major facilitator Superfamily
HFDFGNCO_00131 2.1e-285 thrC 4.2.3.1 E Threonine synthase N terminus
HFDFGNCO_00132 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFDFGNCO_00133 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFDFGNCO_00134 3.2e-101
HFDFGNCO_00135 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFDFGNCO_00136 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFDFGNCO_00138 1.8e-121
HFDFGNCO_00139 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HFDFGNCO_00140 1.3e-84 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFDFGNCO_00141 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HFDFGNCO_00142 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFDFGNCO_00144 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFDFGNCO_00145 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFDFGNCO_00146 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HFDFGNCO_00147 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFDFGNCO_00148 3.3e-138 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFDFGNCO_00149 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFDFGNCO_00150 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFDFGNCO_00151 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFDFGNCO_00152 2.6e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFDFGNCO_00153 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFDFGNCO_00154 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HFDFGNCO_00155 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HFDFGNCO_00156 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HFDFGNCO_00157 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFDFGNCO_00158 2.6e-172 S Bacterial protein of unknown function (DUF881)
HFDFGNCO_00159 4.2e-45 sbp S Protein of unknown function (DUF1290)
HFDFGNCO_00160 1.6e-141 S Bacterial protein of unknown function (DUF881)
HFDFGNCO_00161 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFDFGNCO_00162 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
HFDFGNCO_00163 5.2e-128 yebC K transcriptional regulatory protein
HFDFGNCO_00164 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HFDFGNCO_00165 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFDFGNCO_00166 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFDFGNCO_00167 1.8e-50 yajC U Preprotein translocase subunit
HFDFGNCO_00168 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFDFGNCO_00169 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HFDFGNCO_00170 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HFDFGNCO_00171 1.8e-246
HFDFGNCO_00172 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFDFGNCO_00173 8.2e-34
HFDFGNCO_00174 1.5e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFDFGNCO_00175 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFDFGNCO_00176 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HFDFGNCO_00177 1.1e-69
HFDFGNCO_00178 2.4e-71 L Phage integrase family
HFDFGNCO_00179 4.8e-76 2.1.1.72 H Adenine-specific methyltransferase EcoRI
HFDFGNCO_00180 1.8e-30
HFDFGNCO_00181 1e-56 M domain protein
HFDFGNCO_00182 1.4e-61 S Listeria-Bacteroides repeat domain (List_Bact_rpt)
HFDFGNCO_00183 1.4e-27 3.4.22.70 M Sortase family
HFDFGNCO_00184 7.1e-22 D nuclear chromosome segregation
HFDFGNCO_00185 6.4e-41 M domain protein
HFDFGNCO_00186 7.1e-39 M Sortase family
HFDFGNCO_00192 1.3e-84 2.7.11.1 S HipA-like C-terminal domain
HFDFGNCO_00225 9.4e-12
HFDFGNCO_00226 4.3e-10
HFDFGNCO_00230 5.7e-25
HFDFGNCO_00237 1e-239 purL 1.17.4.1, 6.3.5.3 L intein-mediated protein splicing
HFDFGNCO_00238 8.6e-73 uvrD2 L COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
HFDFGNCO_00239 2.9e-69 S Bifunctional DNA primase/polymerase, N-terminal
HFDFGNCO_00242 1.3e-183 D ftsk spoiiie
HFDFGNCO_00247 2.5e-14
HFDFGNCO_00248 1.1e-69 addB 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HFDFGNCO_00251 9.5e-40 D protein tyrosine kinase activity
HFDFGNCO_00253 2.9e-45
HFDFGNCO_00254 1.1e-55 L COG0675 Transposase and inactivated derivatives
HFDFGNCO_00255 1.4e-163 S COG0433 Predicted ATPase
HFDFGNCO_00256 1.4e-25 dnaN 2.7.7.7 L DNA-directed DNA polymerase activity
HFDFGNCO_00257 6.6e-98 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFDFGNCO_00259 1.1e-19 S Protein of unknown function (DUF2786)
HFDFGNCO_00269 1.3e-84 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_00270 6.7e-32 3.1.1.53 L Calcineurin-like phosphoesterase
HFDFGNCO_00271 5.6e-117 2.7.11.1 S HipA-like C-terminal domain
HFDFGNCO_00276 3.4e-09 S Predicted nucleotidyltransferase
HFDFGNCO_00281 5.6e-88 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_00283 7.6e-55 M NlpC/P60 family
HFDFGNCO_00288 7.1e-55 usp 3.5.1.28 CBM50 S CHAP domain
HFDFGNCO_00290 1.2e-10
HFDFGNCO_00291 2.1e-44 S Domain of unknown function (DUF4160)
HFDFGNCO_00292 2.5e-42 K Protein of unknown function (DUF2442)
HFDFGNCO_00293 2.7e-56 S Bacterial mobilisation protein (MobC)
HFDFGNCO_00294 1.5e-284 ltrBE1 U Relaxase/Mobilisation nuclease domain
HFDFGNCO_00295 1.2e-133 S Protein of unknown function (DUF3801)
HFDFGNCO_00296 2.7e-290
HFDFGNCO_00298 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HFDFGNCO_00299 4.4e-33
HFDFGNCO_00300 1.3e-35
HFDFGNCO_00301 0.0 U Type IV secretory system Conjugative DNA transfer
HFDFGNCO_00304 1.4e-08
HFDFGNCO_00305 1.1e-101 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HFDFGNCO_00306 7.7e-101 K DNA binding
HFDFGNCO_00308 6.1e-50
HFDFGNCO_00309 1.2e-17 U Type IV secretory system Conjugative DNA transfer
HFDFGNCO_00310 1.5e-157 isp2 3.2.1.96 M CHAP domain
HFDFGNCO_00311 0.0 trsE U type IV secretory pathway VirB4
HFDFGNCO_00312 1.8e-62 S PrgI family protein
HFDFGNCO_00313 5.3e-145
HFDFGNCO_00314 5.2e-26
HFDFGNCO_00316 0.0 D Cell surface antigen C-terminus
HFDFGNCO_00317 5.4e-58
HFDFGNCO_00319 3.4e-27
HFDFGNCO_00320 1.2e-102 parA D AAA domain
HFDFGNCO_00321 5.4e-89 S Transcription factor WhiB
HFDFGNCO_00322 2.5e-42
HFDFGNCO_00323 2.2e-186 S Helix-turn-helix domain
HFDFGNCO_00324 8e-15
HFDFGNCO_00325 1.3e-27
HFDFGNCO_00326 5.2e-117
HFDFGNCO_00327 1.5e-67
HFDFGNCO_00329 1.2e-199 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFDFGNCO_00330 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFDFGNCO_00331 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HFDFGNCO_00332 1e-47 S Domain of unknown function (DUF4193)
HFDFGNCO_00333 4.1e-147 S Protein of unknown function (DUF3071)
HFDFGNCO_00334 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
HFDFGNCO_00335 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HFDFGNCO_00336 0.0 lhr L DEAD DEAH box helicase
HFDFGNCO_00337 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
HFDFGNCO_00338 2.4e-79 S Protein of unknown function (DUF2975)
HFDFGNCO_00339 2.5e-242 T PhoQ Sensor
HFDFGNCO_00340 1.5e-222 G Major Facilitator Superfamily
HFDFGNCO_00341 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HFDFGNCO_00342 3.4e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFDFGNCO_00343 1.1e-118
HFDFGNCO_00344 1e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HFDFGNCO_00345 0.0 pknL 2.7.11.1 KLT PASTA
HFDFGNCO_00346 3.3e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
HFDFGNCO_00347 2.9e-97
HFDFGNCO_00348 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFDFGNCO_00349 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFDFGNCO_00350 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFDFGNCO_00351 1.5e-121 recX S Modulates RecA activity
HFDFGNCO_00352 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFDFGNCO_00353 4.3e-46 S Protein of unknown function (DUF3046)
HFDFGNCO_00354 1.6e-80 K Helix-turn-helix XRE-family like proteins
HFDFGNCO_00355 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
HFDFGNCO_00356 1.7e-122 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFDFGNCO_00357 0.0 ftsK D FtsK SpoIIIE family protein
HFDFGNCO_00358 4.2e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFDFGNCO_00359 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HFDFGNCO_00360 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HFDFGNCO_00361 1.4e-176 ydeD EG EamA-like transporter family
HFDFGNCO_00362 1.7e-127 ybhL S Belongs to the BI1 family
HFDFGNCO_00363 6.7e-60 S Domain of unknown function (DUF5067)
HFDFGNCO_00364 2.2e-213 T Histidine kinase
HFDFGNCO_00365 1.8e-127 K helix_turn_helix, Lux Regulon
HFDFGNCO_00366 0.0 S Protein of unknown function DUF262
HFDFGNCO_00367 9e-116 K helix_turn_helix, Lux Regulon
HFDFGNCO_00368 1.2e-244 T Histidine kinase
HFDFGNCO_00369 4.4e-191 V ATPases associated with a variety of cellular activities
HFDFGNCO_00370 7.7e-225 V ABC-2 family transporter protein
HFDFGNCO_00371 4e-229 V ABC-2 family transporter protein
HFDFGNCO_00372 2.9e-209 rhaR1 K helix_turn_helix, arabinose operon control protein
HFDFGNCO_00373 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HFDFGNCO_00374 3.7e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
HFDFGNCO_00375 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFDFGNCO_00376 0.0 ctpE P E1-E2 ATPase
HFDFGNCO_00377 2e-74
HFDFGNCO_00378 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFDFGNCO_00379 2.4e-133 S Protein of unknown function (DUF3159)
HFDFGNCO_00380 2.4e-150 S Protein of unknown function (DUF3710)
HFDFGNCO_00381 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HFDFGNCO_00382 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HFDFGNCO_00383 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
HFDFGNCO_00384 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00385 0.0 E ABC transporter, substrate-binding protein, family 5
HFDFGNCO_00386 0.0 E ABC transporter, substrate-binding protein, family 5
HFDFGNCO_00387 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HFDFGNCO_00388 5.2e-08
HFDFGNCO_00389 2.8e-34
HFDFGNCO_00390 2.6e-194 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HFDFGNCO_00391 3.7e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HFDFGNCO_00392 4e-104
HFDFGNCO_00393 0.0 typA T Elongation factor G C-terminus
HFDFGNCO_00394 2.6e-250 naiP U Sugar (and other) transporter
HFDFGNCO_00395 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
HFDFGNCO_00396 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HFDFGNCO_00397 2e-177 xerD D recombinase XerD
HFDFGNCO_00398 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFDFGNCO_00399 2.1e-25 rpmI J Ribosomal protein L35
HFDFGNCO_00400 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFDFGNCO_00401 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HFDFGNCO_00402 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFDFGNCO_00403 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFDFGNCO_00404 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HFDFGNCO_00405 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
HFDFGNCO_00406 1.2e-36
HFDFGNCO_00407 2.5e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HFDFGNCO_00408 4.6e-280 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFDFGNCO_00409 7.3e-186 V Acetyltransferase (GNAT) domain
HFDFGNCO_00410 5.5e-292 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HFDFGNCO_00411 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HFDFGNCO_00412 4.8e-96 3.6.1.55 F NUDIX domain
HFDFGNCO_00413 0.0 P Belongs to the ABC transporter superfamily
HFDFGNCO_00414 8e-192 dppC EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00415 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00416 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HFDFGNCO_00417 1.7e-218 GK ROK family
HFDFGNCO_00418 2.4e-164 2.7.1.4 G pfkB family carbohydrate kinase
HFDFGNCO_00419 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
HFDFGNCO_00420 7.9e-27
HFDFGNCO_00421 9.3e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HFDFGNCO_00422 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
HFDFGNCO_00423 4e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
HFDFGNCO_00424 1.1e-215 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFDFGNCO_00425 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HFDFGNCO_00426 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFDFGNCO_00427 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFDFGNCO_00428 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFDFGNCO_00429 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFDFGNCO_00430 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HFDFGNCO_00431 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HFDFGNCO_00432 3.8e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFDFGNCO_00433 7e-92 mraZ K Belongs to the MraZ family
HFDFGNCO_00434 0.0 L DNA helicase
HFDFGNCO_00435 8.7e-218 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HFDFGNCO_00436 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFDFGNCO_00437 1e-53 M Lysin motif
HFDFGNCO_00438 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFDFGNCO_00439 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFDFGNCO_00440 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HFDFGNCO_00441 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFDFGNCO_00442 2.9e-113 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HFDFGNCO_00443 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HFDFGNCO_00444 2.1e-191
HFDFGNCO_00445 9.5e-184 V N-Acetylmuramoyl-L-alanine amidase
HFDFGNCO_00446 5.3e-90
HFDFGNCO_00447 3.2e-118 ytrE V ATPases associated with a variety of cellular activities
HFDFGNCO_00448 8e-219 EGP Major facilitator Superfamily
HFDFGNCO_00449 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HFDFGNCO_00450 5.6e-219 S Domain of unknown function (DUF5067)
HFDFGNCO_00451 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
HFDFGNCO_00452 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HFDFGNCO_00453 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFDFGNCO_00454 1.5e-122
HFDFGNCO_00455 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HFDFGNCO_00456 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFDFGNCO_00457 1.2e-258 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFDFGNCO_00458 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HFDFGNCO_00459 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFDFGNCO_00460 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFDFGNCO_00461 4.5e-31 3.1.21.3 V DivIVA protein
HFDFGNCO_00462 1.2e-40 yggT S YGGT family
HFDFGNCO_00463 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFDFGNCO_00464 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFDFGNCO_00465 1.1e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFDFGNCO_00466 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HFDFGNCO_00467 1e-105 S Pilus assembly protein, PilO
HFDFGNCO_00468 2.2e-49 pilN NU PFAM Fimbrial assembly family protein
HFDFGNCO_00469 5.8e-104 pilN NU PFAM Fimbrial assembly family protein
HFDFGNCO_00470 1.8e-63 pilM NU Type IV pilus assembly protein PilM;
HFDFGNCO_00471 2.1e-274 pulE NU Type II/IV secretion system protein
HFDFGNCO_00472 0.0 pilT NU Type II/IV secretion system protein
HFDFGNCO_00473 0.0
HFDFGNCO_00474 1.4e-153 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFDFGNCO_00475 1.1e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFDFGNCO_00476 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFDFGNCO_00477 3e-60 S Thiamine-binding protein
HFDFGNCO_00478 5.4e-192 K helix_turn _helix lactose operon repressor
HFDFGNCO_00479 2.8e-241 lacY P LacY proton/sugar symporter
HFDFGNCO_00480 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HFDFGNCO_00481 1.4e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00482 5.3e-206 P NMT1/THI5 like
HFDFGNCO_00483 1.4e-218 iunH1 3.2.2.1 F nucleoside hydrolase
HFDFGNCO_00484 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFDFGNCO_00485 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
HFDFGNCO_00486 0.0 I acetylesterase activity
HFDFGNCO_00487 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HFDFGNCO_00488 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HFDFGNCO_00489 7e-236 2.7.11.1 NU Tfp pilus assembly protein FimV
HFDFGNCO_00491 3.2e-74 S Protein of unknown function (DUF3052)
HFDFGNCO_00492 1.3e-154 lon T Belongs to the peptidase S16 family
HFDFGNCO_00493 1.7e-285 S Zincin-like metallopeptidase
HFDFGNCO_00494 1.8e-281 uvrD2 3.6.4.12 L DNA helicase
HFDFGNCO_00495 2.2e-271 mphA S Aminoglycoside phosphotransferase
HFDFGNCO_00496 3.6e-32 S Protein of unknown function (DUF3107)
HFDFGNCO_00497 1.1e-172 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HFDFGNCO_00498 1.5e-118 S Vitamin K epoxide reductase
HFDFGNCO_00499 2.3e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HFDFGNCO_00500 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFDFGNCO_00501 2.4e-19 K Cro/C1-type HTH DNA-binding domain
HFDFGNCO_00502 3e-13 nprA K sequence-specific DNA binding
HFDFGNCO_00505 1.3e-12 S Plasmid replication protein
HFDFGNCO_00509 7.7e-171 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFDFGNCO_00510 5.2e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFDFGNCO_00512 3.6e-85 ptpA 3.1.3.48 T low molecular weight
HFDFGNCO_00513 6.4e-130 folA 1.5.1.3 H dihydrofolate reductase
HFDFGNCO_00514 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFDFGNCO_00515 7.7e-73 attW O OsmC-like protein
HFDFGNCO_00516 1.3e-190 T Universal stress protein family
HFDFGNCO_00517 1.3e-79 M NlpC/P60 family
HFDFGNCO_00518 1.3e-165 usp 3.5.1.28 CBM50 S CHAP domain
HFDFGNCO_00519 2.4e-217 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFDFGNCO_00520 6.2e-41
HFDFGNCO_00521 3.6e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFDFGNCO_00522 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
HFDFGNCO_00523 0.0 4.2.1.53 S MCRA family
HFDFGNCO_00524 3.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFDFGNCO_00525 1.5e-150 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HFDFGNCO_00526 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFDFGNCO_00528 7.5e-214 araJ EGP Major facilitator Superfamily
HFDFGNCO_00529 0.0 S Domain of unknown function (DUF4037)
HFDFGNCO_00530 2.7e-117 S Protein of unknown function (DUF4125)
HFDFGNCO_00531 5.1e-99
HFDFGNCO_00532 2.6e-179 pspC KT PspC domain
HFDFGNCO_00533 3.4e-257 tcsS3 KT PspC domain
HFDFGNCO_00534 1.6e-120 degU K helix_turn_helix, Lux Regulon
HFDFGNCO_00535 5.8e-100 Q Isochorismatase family
HFDFGNCO_00536 4.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
HFDFGNCO_00537 8.3e-190 yegV G pfkB family carbohydrate kinase
HFDFGNCO_00538 6.7e-187 yegU O ADP-ribosylglycohydrolase
HFDFGNCO_00540 9.2e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFDFGNCO_00541 8.3e-199 I Diacylglycerol kinase catalytic domain
HFDFGNCO_00542 2e-124 K helix_turn_helix, Lux Regulon
HFDFGNCO_00543 0.0 tcsS2 T Histidine kinase
HFDFGNCO_00544 0.0 S Psort location CytoplasmicMembrane, score 9.99
HFDFGNCO_00545 3.6e-241 V ABC transporter permease
HFDFGNCO_00546 8.8e-154 V ABC transporter
HFDFGNCO_00547 5.1e-150 T HD domain
HFDFGNCO_00548 1e-167 S Glutamine amidotransferase domain
HFDFGNCO_00549 0.0 kup P Transport of potassium into the cell
HFDFGNCO_00550 1.5e-183 tatD L TatD related DNase
HFDFGNCO_00551 1.1e-239 G Alpha-L-arabinofuranosidase C-terminus
HFDFGNCO_00552 5.3e-206 G Alpha-L-arabinofuranosidase C-terminus
HFDFGNCO_00553 6.6e-233 G Alpha galactosidase A
HFDFGNCO_00554 3.2e-223 K helix_turn _helix lactose operon repressor
HFDFGNCO_00555 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_00556 8e-126
HFDFGNCO_00557 0.0 yknV V ABC transporter
HFDFGNCO_00558 0.0 mdlA2 V ABC transporter
HFDFGNCO_00559 1.1e-214 lipA I Hydrolase, alpha beta domain protein
HFDFGNCO_00560 5e-27 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00561 1.2e-154 I alpha/beta hydrolase fold
HFDFGNCO_00562 2.2e-234 M Protein of unknown function (DUF2961)
HFDFGNCO_00563 0.0 M probably involved in cell wall
HFDFGNCO_00564 2.9e-251 3.2.1.14 GH18 S Carbohydrate binding domain
HFDFGNCO_00565 1.2e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFDFGNCO_00566 2.8e-157 arbG K CAT RNA binding domain
HFDFGNCO_00567 0.0 crr G pts system, glucose-specific IIABC component
HFDFGNCO_00568 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HFDFGNCO_00569 2.1e-151 T LytTr DNA-binding domain
HFDFGNCO_00570 3.1e-248 T GHKL domain
HFDFGNCO_00571 7.8e-214 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFDFGNCO_00572 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFDFGNCO_00574 3.8e-108
HFDFGNCO_00575 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFDFGNCO_00576 8.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HFDFGNCO_00577 5.1e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFDFGNCO_00578 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFDFGNCO_00579 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFDFGNCO_00580 6.1e-191 nusA K Participates in both transcription termination and antitermination
HFDFGNCO_00581 2e-102
HFDFGNCO_00583 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFDFGNCO_00584 1.3e-66 rplQ J Ribosomal protein L17
HFDFGNCO_00585 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFDFGNCO_00586 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFDFGNCO_00587 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFDFGNCO_00588 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFDFGNCO_00589 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFDFGNCO_00590 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFDFGNCO_00591 9.9e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFDFGNCO_00592 9.8e-74 rplO J binds to the 23S rRNA
HFDFGNCO_00593 3.4e-25 rpmD J Ribosomal protein L30p/L7e
HFDFGNCO_00594 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFDFGNCO_00595 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFDFGNCO_00596 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFDFGNCO_00597 1.1e-62 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFDFGNCO_00598 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_00599 1.7e-125 S Short repeat of unknown function (DUF308)
HFDFGNCO_00600 1.1e-47 S Antitoxin component of a toxin-antitoxin (TA) module
HFDFGNCO_00601 3.4e-55 DJ Addiction module toxin, RelE StbE family
HFDFGNCO_00602 4.5e-13 S Psort location Extracellular, score 8.82
HFDFGNCO_00603 1.7e-232 EGP Major facilitator Superfamily
HFDFGNCO_00604 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFDFGNCO_00605 2e-269 KLT Domain of unknown function (DUF4032)
HFDFGNCO_00606 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
HFDFGNCO_00607 2.8e-131 K LytTr DNA-binding domain
HFDFGNCO_00608 2.7e-234 T GHKL domain
HFDFGNCO_00609 1.2e-72
HFDFGNCO_00610 9.2e-216 clcA_2 P Voltage gated chloride channel
HFDFGNCO_00611 3.8e-179 S Psort location Cytoplasmic, score
HFDFGNCO_00612 1.1e-74 S GtrA-like protein
HFDFGNCO_00613 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HFDFGNCO_00614 3.4e-121 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
HFDFGNCO_00615 2.8e-81 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
HFDFGNCO_00616 1.1e-113 vex2 V ABC transporter, ATP-binding protein
HFDFGNCO_00617 5e-213 vex1 V Efflux ABC transporter, permease protein
HFDFGNCO_00618 2e-242 vex3 V ABC transporter permease
HFDFGNCO_00619 1.7e-17 G Major facilitator Superfamily
HFDFGNCO_00620 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_00621 2.7e-188 lacR K Transcriptional regulator, LacI family
HFDFGNCO_00622 1.8e-103 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HFDFGNCO_00623 3.4e-08 L Phage integrase family
HFDFGNCO_00624 8.4e-18
HFDFGNCO_00625 7.8e-21
HFDFGNCO_00627 1.3e-34 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
HFDFGNCO_00628 5.1e-58 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
HFDFGNCO_00629 2.9e-18 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
HFDFGNCO_00630 6.5e-188 rgpD 3.6.3.38, 3.6.3.40 GM ABC transporter, ATP-binding protein
HFDFGNCO_00631 1.4e-119 rgpC U Transport permease protein
HFDFGNCO_00632 5.7e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFDFGNCO_00633 1.6e-34 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFDFGNCO_00634 6.5e-56 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFDFGNCO_00635 1.9e-27 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFDFGNCO_00636 1.9e-39 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFDFGNCO_00637 6.6e-211 L HTH-like domain
HFDFGNCO_00638 5.6e-97 L HTH-like domain
HFDFGNCO_00641 1.4e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HFDFGNCO_00642 4.4e-244 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HFDFGNCO_00643 1.1e-250 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFDFGNCO_00644 2.1e-137 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HFDFGNCO_00645 8e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFDFGNCO_00646 1.1e-77 soxR K MerR, DNA binding
HFDFGNCO_00647 4.6e-196 yghZ C Aldo/keto reductase family
HFDFGNCO_00648 3.2e-58 S Protein of unknown function (DUF3039)
HFDFGNCO_00649 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFDFGNCO_00650 4.2e-133
HFDFGNCO_00651 1.8e-113 yceD S Uncharacterized ACR, COG1399
HFDFGNCO_00652 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFDFGNCO_00653 4.8e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFDFGNCO_00654 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HFDFGNCO_00655 4.9e-91 ilvN 2.2.1.6 E ACT domain
HFDFGNCO_00656 6.4e-96
HFDFGNCO_00657 0.0 yjjK S ABC transporter
HFDFGNCO_00658 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
HFDFGNCO_00659 9.3e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFDFGNCO_00660 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFDFGNCO_00661 7.6e-178 S Endonuclease/Exonuclease/phosphatase family
HFDFGNCO_00662 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFDFGNCO_00663 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HFDFGNCO_00664 6.1e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFDFGNCO_00665 1.9e-151 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFDFGNCO_00666 1.4e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HFDFGNCO_00667 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HFDFGNCO_00668 8.4e-30 rpmB J Ribosomal L28 family
HFDFGNCO_00669 9.7e-226 yxiO S Vacuole effluxer Atg22 like
HFDFGNCO_00670 5.1e-128 gntR K FCD
HFDFGNCO_00671 9.5e-79 gntK 2.7.1.12 F Shikimate kinase
HFDFGNCO_00672 2.1e-225 gnuT EG GntP family permease
HFDFGNCO_00673 6.1e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
HFDFGNCO_00674 9.8e-230 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HFDFGNCO_00675 5.7e-126 K Bacterial regulatory proteins, tetR family
HFDFGNCO_00676 7.1e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00677 7.7e-230 MA20_36090 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00678 1.1e-136 M Mechanosensitive ion channel
HFDFGNCO_00679 1.6e-178 S CAAX protease self-immunity
HFDFGNCO_00680 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFDFGNCO_00681 1.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HFDFGNCO_00682 2.3e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
HFDFGNCO_00683 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFDFGNCO_00684 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HFDFGNCO_00685 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFDFGNCO_00686 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFDFGNCO_00687 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HFDFGNCO_00688 1.5e-275 S Calcineurin-like phosphoesterase
HFDFGNCO_00691 4.5e-299 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFDFGNCO_00692 1.1e-106 S Protein of unknown function (DUF805)
HFDFGNCO_00693 7e-184
HFDFGNCO_00694 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HFDFGNCO_00695 1e-262 EGP Major facilitator Superfamily
HFDFGNCO_00696 7.1e-95 S GtrA-like protein
HFDFGNCO_00697 6.7e-62 S Macrophage migration inhibitory factor (MIF)
HFDFGNCO_00698 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HFDFGNCO_00699 0.0 pepD E Peptidase family C69
HFDFGNCO_00700 1.1e-106 S Phosphatidylethanolamine-binding protein
HFDFGNCO_00701 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFDFGNCO_00702 6e-39 ptsH G PTS HPr component phosphorylation site
HFDFGNCO_00703 2.2e-185 K helix_turn _helix lactose operon repressor
HFDFGNCO_00704 4e-88 K UTRA domain
HFDFGNCO_00705 1.1e-211 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HFDFGNCO_00706 9.1e-36 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HFDFGNCO_00707 5e-46 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFDFGNCO_00708 1.9e-193 holB 2.7.7.7 L DNA polymerase III
HFDFGNCO_00709 2.7e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFDFGNCO_00710 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFDFGNCO_00711 2.3e-191 3.6.1.27 I PAP2 superfamily
HFDFGNCO_00712 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
HFDFGNCO_00713 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HFDFGNCO_00714 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HFDFGNCO_00715 2e-27 S Beta-L-arabinofuranosidase, GH127
HFDFGNCO_00716 5e-101 S Protein of unknown function, DUF624
HFDFGNCO_00717 1.1e-184 G beta-fructofuranosidase activity
HFDFGNCO_00718 8.3e-163 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00719 2.3e-168 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00720 4.4e-294 G Bacterial extracellular solute-binding protein
HFDFGNCO_00721 1.7e-206 abf G Glycosyl hydrolases family 43
HFDFGNCO_00722 1.1e-195 K helix_turn _helix lactose operon repressor
HFDFGNCO_00723 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
HFDFGNCO_00724 2.7e-256 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HFDFGNCO_00725 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HFDFGNCO_00726 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFDFGNCO_00727 2.3e-303 S Calcineurin-like phosphoesterase
HFDFGNCO_00728 2.4e-115
HFDFGNCO_00729 3.8e-40
HFDFGNCO_00730 1.4e-38 K helix_turn_helix, Lux Regulon
HFDFGNCO_00731 6.7e-07 2.7.13.3 T Histidine kinase
HFDFGNCO_00732 1.3e-23 S Protein of unknown function (DUF1778)
HFDFGNCO_00733 9.1e-47 K Acetyltransferase (GNAT) family
HFDFGNCO_00734 9.2e-160 K Periplasmic binding protein domain
HFDFGNCO_00735 7.4e-142 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00736 5.7e-156 malC G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00737 4.1e-232 G Bacterial extracellular solute-binding protein
HFDFGNCO_00738 1.9e-271 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_00739 0.0 3.2.1.22 G lipolytic protein G-D-S-L family
HFDFGNCO_00740 2.7e-210 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFDFGNCO_00741 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HFDFGNCO_00742 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HFDFGNCO_00743 7.7e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFDFGNCO_00744 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HFDFGNCO_00745 1.1e-96 K Bacterial regulatory proteins, tetR family
HFDFGNCO_00746 7.9e-193 S Psort location CytoplasmicMembrane, score
HFDFGNCO_00747 8.8e-212 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HFDFGNCO_00748 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
HFDFGNCO_00749 1.9e-59 U TadE-like protein
HFDFGNCO_00750 1.3e-42 S Protein of unknown function (DUF4244)
HFDFGNCO_00751 1.8e-87 gspF NU Type II secretion system (T2SS), protein F
HFDFGNCO_00752 3.4e-132 U Type ii secretion system
HFDFGNCO_00753 8e-185 cpaF U Type II IV secretion system protein
HFDFGNCO_00754 5.5e-141 cpaE D bacterial-type flagellum organization
HFDFGNCO_00756 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFDFGNCO_00757 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HFDFGNCO_00758 3.9e-91
HFDFGNCO_00759 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFDFGNCO_00760 3.6e-207 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HFDFGNCO_00761 0.0 G Bacterial Ig-like domain (group 4)
HFDFGNCO_00762 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
HFDFGNCO_00763 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HFDFGNCO_00764 6e-146 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00765 3.1e-167 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00766 4.3e-07 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00767 4.3e-242 G Bacterial extracellular solute-binding protein
HFDFGNCO_00768 4.1e-192 K Periplasmic binding protein domain
HFDFGNCO_00769 0.0 ubiB S ABC1 family
HFDFGNCO_00770 1e-27 S granule-associated protein
HFDFGNCO_00771 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HFDFGNCO_00772 1.5e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HFDFGNCO_00773 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFDFGNCO_00774 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HFDFGNCO_00775 1e-54 glnB K Nitrogen regulatory protein P-II
HFDFGNCO_00776 1.2e-236 amt U Ammonium Transporter Family
HFDFGNCO_00777 3.6e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFDFGNCO_00778 1.1e-107 icaR K Bacterial regulatory proteins, tetR family
HFDFGNCO_00780 1.2e-194 XK27_01805 M Glycosyltransferase like family 2
HFDFGNCO_00781 3e-301 pepD E Peptidase family C69
HFDFGNCO_00784 6e-38 nrdH O Glutaredoxin
HFDFGNCO_00785 1.6e-225 S Putative ABC-transporter type IV
HFDFGNCO_00786 0.0 pip S YhgE Pip domain protein
HFDFGNCO_00787 1.4e-274 pip S YhgE Pip domain protein
HFDFGNCO_00788 7.8e-88 K Psort location Cytoplasmic, score 8.87
HFDFGNCO_00789 2.6e-63 S FMN_bind
HFDFGNCO_00790 9e-150 macB V ABC transporter, ATP-binding protein
HFDFGNCO_00791 7.7e-201 Z012_06715 V FtsX-like permease family
HFDFGNCO_00793 2.1e-220 macB_2 V ABC transporter permease
HFDFGNCO_00794 8e-230 S Predicted membrane protein (DUF2318)
HFDFGNCO_00795 1.4e-92 tpd P Fe2+ transport protein
HFDFGNCO_00796 1.4e-293 efeU_1 P Iron permease FTR1 family
HFDFGNCO_00797 4.4e-237 G MFS/sugar transport protein
HFDFGNCO_00798 7.9e-121 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFDFGNCO_00799 7.1e-304 lmrA2 V ABC transporter transmembrane region
HFDFGNCO_00800 1.1e-283 lmrA1 V ABC transporter, ATP-binding protein
HFDFGNCO_00801 6.4e-58 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HFDFGNCO_00802 5.1e-182 1.1.1.65 C Aldo/keto reductase family
HFDFGNCO_00803 2.5e-26 thiS 2.8.1.10 H ThiS family
HFDFGNCO_00804 8.4e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
HFDFGNCO_00805 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HFDFGNCO_00806 9.9e-275 cycA E Amino acid permease
HFDFGNCO_00807 2.5e-89 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00808 7.6e-211 M LPXTG cell wall anchor motif
HFDFGNCO_00809 0.0 inlJ M domain protein
HFDFGNCO_00810 8.4e-183 3.4.22.70 M Sortase family
HFDFGNCO_00811 6.3e-76 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_00812 3.3e-227 P Sodium/hydrogen exchanger family
HFDFGNCO_00813 0.0 V FtsX-like permease family
HFDFGNCO_00814 5.4e-270 aroP E aromatic amino acid transport protein AroP K03293
HFDFGNCO_00815 5.6e-189 K helix_turn _helix lactose operon repressor
HFDFGNCO_00816 5.8e-40 G beta-mannosidase
HFDFGNCO_00817 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HFDFGNCO_00818 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFDFGNCO_00819 5.3e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFDFGNCO_00820 3.5e-252 yhjE EGP Sugar (and other) transporter
HFDFGNCO_00821 4.3e-270 scrT G Transporter major facilitator family protein
HFDFGNCO_00822 4.9e-10 S Protein of unknown function, DUF624
HFDFGNCO_00823 3.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HFDFGNCO_00824 4.2e-195 K helix_turn _helix lactose operon repressor
HFDFGNCO_00825 1.4e-29 E Receptor family ligand binding region
HFDFGNCO_00826 1.3e-101 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFDFGNCO_00827 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFDFGNCO_00828 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFDFGNCO_00829 0.0 macB_2 V ATPases associated with a variety of cellular activities
HFDFGNCO_00830 8.5e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFDFGNCO_00831 5.8e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HFDFGNCO_00832 1.7e-137 sapF E ATPases associated with a variety of cellular activities
HFDFGNCO_00833 3.9e-134 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HFDFGNCO_00834 6.6e-133 EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00835 1.4e-162 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00836 3.3e-292 E ABC transporter, substrate-binding protein, family 5
HFDFGNCO_00837 2e-241 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFDFGNCO_00838 2.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HFDFGNCO_00839 4.1e-275 G Bacterial extracellular solute-binding protein
HFDFGNCO_00840 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_00841 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HFDFGNCO_00842 5.5e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HFDFGNCO_00843 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFDFGNCO_00844 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HFDFGNCO_00845 2.1e-129 yecS E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00846 6.4e-128 pknD ET ABC transporter, substrate-binding protein, family 3
HFDFGNCO_00847 9.4e-151 pknD ET ABC transporter, substrate-binding protein, family 3
HFDFGNCO_00848 3e-157 pknD ET ABC transporter, substrate-binding protein, family 3
HFDFGNCO_00849 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFDFGNCO_00850 8.5e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
HFDFGNCO_00851 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HFDFGNCO_00852 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
HFDFGNCO_00853 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFDFGNCO_00854 4e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFDFGNCO_00855 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HFDFGNCO_00856 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HFDFGNCO_00857 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
HFDFGNCO_00858 0.0 pepO 3.4.24.71 O Peptidase family M13
HFDFGNCO_00859 5.1e-93 L Single-strand binding protein family
HFDFGNCO_00860 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFDFGNCO_00861 4.3e-269 recD2 3.6.4.12 L PIF1-like helicase
HFDFGNCO_00862 4.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
HFDFGNCO_00863 2.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HFDFGNCO_00864 2.7e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HFDFGNCO_00865 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HFDFGNCO_00866 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
HFDFGNCO_00867 1.9e-124 livF E ATPases associated with a variety of cellular activities
HFDFGNCO_00868 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
HFDFGNCO_00869 1.4e-196 livM U Belongs to the binding-protein-dependent transport system permease family
HFDFGNCO_00870 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
HFDFGNCO_00871 3e-218 livK E Receptor family ligand binding region
HFDFGNCO_00872 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFDFGNCO_00873 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFDFGNCO_00874 1.5e-35 rpmE J Binds the 23S rRNA
HFDFGNCO_00876 6.8e-226 xylR GK ROK family
HFDFGNCO_00877 2.9e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HFDFGNCO_00878 2.1e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HFDFGNCO_00879 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HFDFGNCO_00880 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HFDFGNCO_00881 7e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00882 1.3e-185 MA20_14025 U Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00883 5.5e-239 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HFDFGNCO_00884 1e-182 K Bacterial regulatory proteins, lacI family
HFDFGNCO_00885 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HFDFGNCO_00886 1.3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HFDFGNCO_00887 6.3e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HFDFGNCO_00888 5.8e-296 S Amidohydrolase family
HFDFGNCO_00889 6.7e-52 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFDFGNCO_00890 2.4e-150 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
HFDFGNCO_00891 1.8e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFDFGNCO_00892 5.5e-180 V Beta-lactamase
HFDFGNCO_00893 0.0 yjjK S ATP-binding cassette protein, ChvD family
HFDFGNCO_00894 8.5e-165 tesB I Thioesterase-like superfamily
HFDFGNCO_00895 3.1e-93 S Protein of unknown function (DUF3180)
HFDFGNCO_00896 4.9e-274 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFDFGNCO_00897 1.8e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFDFGNCO_00898 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HFDFGNCO_00899 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFDFGNCO_00900 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFDFGNCO_00901 2.3e-201 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFDFGNCO_00902 1.7e-231 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HFDFGNCO_00903 6.3e-232 epsG M Glycosyl transferase family 21
HFDFGNCO_00904 8.2e-237 S AI-2E family transporter
HFDFGNCO_00905 3e-178 3.4.14.13 M Glycosyltransferase like family 2
HFDFGNCO_00906 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HFDFGNCO_00907 0.0 yliE T Putative diguanylate phosphodiesterase
HFDFGNCO_00908 2.2e-111 S Domain of unknown function (DUF4956)
HFDFGNCO_00909 2.2e-159 P VTC domain
HFDFGNCO_00910 1.6e-299 cotH M CotH kinase protein
HFDFGNCO_00911 5e-53 pip 3.4.11.5 S alpha/beta hydrolase fold
HFDFGNCO_00912 3.7e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFDFGNCO_00913 4.7e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFDFGNCO_00914 7.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFDFGNCO_00915 1.6e-227 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFDFGNCO_00916 6.2e-156 L Transposase DDE domain
HFDFGNCO_00917 1.1e-26 regB 2.7.13.3 T GHKL domain
HFDFGNCO_00918 2.1e-23 L Transposase
HFDFGNCO_00919 8.5e-27 KT LytTr DNA-binding domain
HFDFGNCO_00921 1.4e-16
HFDFGNCO_00922 5e-20
HFDFGNCO_00923 3.2e-25
HFDFGNCO_00924 2.4e-57 V ABC transporter, ATP-binding protein
HFDFGNCO_00925 1.3e-143 S protein conserved in bacteria
HFDFGNCO_00928 9.8e-178 M Domain of unknown function (DUF1906)
HFDFGNCO_00929 1e-31
HFDFGNCO_00930 2.7e-14
HFDFGNCO_00931 2.1e-30 S Bacteriophage holin family
HFDFGNCO_00932 3.4e-43 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFDFGNCO_00933 7.4e-59 S Transposon-encoded protein TnpV
HFDFGNCO_00934 1.3e-48 yjdF S Protein of unknown function (DUF2992)
HFDFGNCO_00936 1.4e-60 KT Domain of unknown function (DUF4825)
HFDFGNCO_00937 1.1e-49 traA L MobA MobL family protein
HFDFGNCO_00938 4.9e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HFDFGNCO_00939 9.4e-152 ypfH S Phospholipase/Carboxylesterase
HFDFGNCO_00940 0.0 yjcE P Sodium/hydrogen exchanger family
HFDFGNCO_00941 4.1e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFDFGNCO_00942 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HFDFGNCO_00943 4e-231 nagC GK ROK family
HFDFGNCO_00944 2.2e-243 msmE7 G Bacterial extracellular solute-binding protein
HFDFGNCO_00945 6.6e-157 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00946 2.6e-155 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_00947 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFDFGNCO_00948 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HFDFGNCO_00949 2.3e-144 cobB2 K Sir2 family
HFDFGNCO_00951 6.6e-175 I alpha/beta hydrolase fold
HFDFGNCO_00952 8.5e-193 L Integrase core domain
HFDFGNCO_00953 6.7e-248 S zinc finger
HFDFGNCO_00954 2e-71 S Bacterial PH domain
HFDFGNCO_00955 1.5e-76
HFDFGNCO_00956 7e-264 V Domain of unknown function (DUF3427)
HFDFGNCO_00957 5.4e-104 KL Domain of unknown function (DUF3427)
HFDFGNCO_00958 4.1e-71 L Transposase IS200 like
HFDFGNCO_00959 1.1e-222 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_00960 1.2e-21 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HFDFGNCO_00961 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_00962 6.2e-185 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HFDFGNCO_00963 6.6e-74 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HFDFGNCO_00964 1.2e-232 aspB E Aminotransferase class-V
HFDFGNCO_00965 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HFDFGNCO_00966 2.2e-99 tmp1 S Domain of unknown function (DUF4391)
HFDFGNCO_00967 3.8e-23
HFDFGNCO_00968 3.5e-43 V ATPases associated with a variety of cellular activities
HFDFGNCO_00969 5.3e-198 S Endonuclease/Exonuclease/phosphatase family
HFDFGNCO_00971 5.3e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFDFGNCO_00972 8.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFDFGNCO_00973 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HFDFGNCO_00974 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFDFGNCO_00975 6.1e-157 hgdC I BadF/BadG/BcrA/BcrD ATPase family
HFDFGNCO_00976 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HFDFGNCO_00977 3.7e-259 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HFDFGNCO_00978 2e-120 K Bacterial regulatory proteins, tetR family
HFDFGNCO_00979 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HFDFGNCO_00980 6.7e-113 K Bacterial regulatory proteins, tetR family
HFDFGNCO_00981 2.8e-241 G Transporter major facilitator family protein
HFDFGNCO_00982 1.9e-274 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HFDFGNCO_00983 6.2e-134 K transcriptional regulator
HFDFGNCO_00984 7.2e-223 blt G MFS/sugar transport protein
HFDFGNCO_00985 0.0 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HFDFGNCO_00986 6e-251 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HFDFGNCO_00987 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
HFDFGNCO_00988 1.2e-238 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HFDFGNCO_00989 3.4e-111 K Bacterial regulatory proteins, tetR family
HFDFGNCO_00990 1.1e-225 hsvB 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
HFDFGNCO_00991 2.8e-219 P Major Facilitator Superfamily
HFDFGNCO_00992 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HFDFGNCO_00993 8e-221 lmrB U Major Facilitator Superfamily
HFDFGNCO_00994 6.3e-14 K helix_turn_helix, mercury resistance
HFDFGNCO_00995 1.2e-117 K Periplasmic binding protein domain
HFDFGNCO_00996 4.4e-215 EGP Major facilitator Superfamily
HFDFGNCO_00997 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
HFDFGNCO_00998 1.9e-181 G Transporter major facilitator family protein
HFDFGNCO_00999 4.7e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFDFGNCO_01000 1.8e-104 K Bacterial regulatory proteins, tetR family
HFDFGNCO_01001 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HFDFGNCO_01002 1.6e-55 K MarR family
HFDFGNCO_01003 1.1e-24 K MarR family
HFDFGNCO_01004 0.0 V ABC transporter, ATP-binding protein
HFDFGNCO_01005 0.0 V ABC transporter transmembrane region
HFDFGNCO_01006 2.8e-185 lacR K Transcriptional regulator, LacI family
HFDFGNCO_01007 1e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
HFDFGNCO_01008 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFDFGNCO_01010 4.7e-88 S Phospholipase/Carboxylesterase
HFDFGNCO_01011 1.1e-18 S Fic/DOC family
HFDFGNCO_01012 4.1e-128 S Fic/DOC family
HFDFGNCO_01013 1.9e-301 L DEAD-like helicases superfamily
HFDFGNCO_01014 2.8e-101 cas5d S CRISPR-associated protein (Cas_Cas5)
HFDFGNCO_01015 1.1e-134 csd1 S CRISPR-associated protein (Cas_Csd1)
HFDFGNCO_01016 2e-41 csd1 S CRISPR-associated protein (Cas_Csd1)
HFDFGNCO_01017 2.2e-144 cas7c L CRISPR-associated protein Cas7
HFDFGNCO_01018 3.6e-96 cas4 3.1.12.1 L Domain of unknown function DUF83
HFDFGNCO_01019 2.9e-153 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFDFGNCO_01020 3.8e-34 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFDFGNCO_01021 1e-119 S Phospholipase/Carboxylesterase
HFDFGNCO_01022 3.3e-241 patB 4.4.1.8 E Aminotransferase, class I II
HFDFGNCO_01023 3e-187 K LysR substrate binding domain protein
HFDFGNCO_01024 6.3e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFDFGNCO_01025 1.9e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFDFGNCO_01026 3.1e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFDFGNCO_01027 1.7e-105 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFDFGNCO_01028 5.4e-303 E ABC transporter, substrate-binding protein, family 5
HFDFGNCO_01029 7.2e-156 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HFDFGNCO_01030 3.5e-51 S Patatin-like phospholipase
HFDFGNCO_01031 0.0 fhs 6.3.4.3 H Formyltetrahydrofolate synthetase
HFDFGNCO_01032 1.7e-136 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_01033 2.1e-264 lacS G Psort location CytoplasmicMembrane, score 10.00
HFDFGNCO_01034 5.6e-211 GK ROK family
HFDFGNCO_01035 4.2e-242 G Bacterial extracellular solute-binding protein
HFDFGNCO_01036 7.5e-147 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01037 4.4e-164 G ABC transporter permease
HFDFGNCO_01038 1.9e-172 2.7.1.2 GK ROK family
HFDFGNCO_01039 0.0 G Glycosyl hydrolase family 20, domain 2
HFDFGNCO_01040 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFDFGNCO_01041 5.7e-223 nagA 3.5.1.25 G Amidohydrolase family
HFDFGNCO_01042 2.3e-187 lacR K Transcriptional regulator, LacI family
HFDFGNCO_01043 5.2e-226 T Diguanylate cyclase, GGDEF domain
HFDFGNCO_01044 4e-211 metY 2.5.1.49 E Aminotransferase class-V
HFDFGNCO_01045 3.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HFDFGNCO_01046 3.1e-83 yraN L Belongs to the UPF0102 family
HFDFGNCO_01047 2.3e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
HFDFGNCO_01048 2.7e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HFDFGNCO_01049 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HFDFGNCO_01050 7.5e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HFDFGNCO_01051 4.8e-117 safC S O-methyltransferase
HFDFGNCO_01052 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HFDFGNCO_01055 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFDFGNCO_01056 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFDFGNCO_01057 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFDFGNCO_01058 0.0 E ABC transporter, substrate-binding protein, family 5
HFDFGNCO_01059 9.8e-259 EGP Major facilitator Superfamily
HFDFGNCO_01060 1e-249 rarA L Recombination factor protein RarA
HFDFGNCO_01061 0.0 L DEAD DEAH box helicase
HFDFGNCO_01062 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HFDFGNCO_01063 1e-199 gluD E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01064 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01065 1.4e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
HFDFGNCO_01066 4.4e-144 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HFDFGNCO_01067 3.3e-138 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
HFDFGNCO_01068 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01069 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HFDFGNCO_01070 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HFDFGNCO_01071 5.7e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HFDFGNCO_01072 1.6e-140 3.5.2.10 S Creatinine amidohydrolase
HFDFGNCO_01073 5e-246 proP EGP Sugar (and other) transporter
HFDFGNCO_01074 4.7e-285 purR QT Purine catabolism regulatory protein-like family
HFDFGNCO_01075 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
HFDFGNCO_01076 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HFDFGNCO_01077 1e-187 uspA T Belongs to the universal stress protein A family
HFDFGNCO_01078 9.8e-182 S Protein of unknown function (DUF3027)
HFDFGNCO_01079 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
HFDFGNCO_01080 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFDFGNCO_01081 6.8e-133 KT Response regulator receiver domain protein
HFDFGNCO_01082 6.6e-124
HFDFGNCO_01084 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFDFGNCO_01085 8.5e-77 S LytR cell envelope-related transcriptional attenuator
HFDFGNCO_01086 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFDFGNCO_01087 6.8e-182 moxR S ATPase family associated with various cellular activities (AAA)
HFDFGNCO_01088 5.5e-175 S Protein of unknown function DUF58
HFDFGNCO_01089 4.4e-89
HFDFGNCO_01090 4.7e-191 S von Willebrand factor (vWF) type A domain
HFDFGNCO_01091 1.1e-181 S von Willebrand factor (vWF) type A domain
HFDFGNCO_01092 1.3e-62
HFDFGNCO_01093 1e-276 S PGAP1-like protein
HFDFGNCO_01094 2.1e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HFDFGNCO_01095 0.0 S Lysylphosphatidylglycerol synthase TM region
HFDFGNCO_01096 1.4e-41 hup L Belongs to the bacterial histone-like protein family
HFDFGNCO_01097 1.8e-57
HFDFGNCO_01098 9.7e-141 C FMN binding
HFDFGNCO_01099 1.7e-279 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HFDFGNCO_01100 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HFDFGNCO_01101 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
HFDFGNCO_01102 1.6e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HFDFGNCO_01103 4.4e-283 arc O AAA ATPase forming ring-shaped complexes
HFDFGNCO_01104 3.5e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HFDFGNCO_01105 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFDFGNCO_01106 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFDFGNCO_01107 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFDFGNCO_01108 1.6e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFDFGNCO_01109 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFDFGNCO_01110 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HFDFGNCO_01112 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HFDFGNCO_01113 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HFDFGNCO_01114 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HFDFGNCO_01115 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
HFDFGNCO_01116 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFDFGNCO_01117 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFDFGNCO_01118 1.5e-42 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFDFGNCO_01119 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HFDFGNCO_01120 2.7e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFDFGNCO_01121 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFDFGNCO_01122 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HFDFGNCO_01123 4.7e-244 pbuX F Permease family
HFDFGNCO_01124 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFDFGNCO_01125 0.0 pcrA 3.6.4.12 L DNA helicase
HFDFGNCO_01126 1.7e-61 S Domain of unknown function (DUF4418)
HFDFGNCO_01127 5.3e-215 V FtsX-like permease family
HFDFGNCO_01128 3e-148 lolD V ABC transporter
HFDFGNCO_01129 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFDFGNCO_01130 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFDFGNCO_01131 5.6e-129 pgm3 G Phosphoglycerate mutase family
HFDFGNCO_01132 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HFDFGNCO_01133 2.5e-36
HFDFGNCO_01134 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFDFGNCO_01135 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFDFGNCO_01136 1.3e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFDFGNCO_01137 9.3e-57 3.4.23.43 S Type IV leader peptidase family
HFDFGNCO_01138 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFDFGNCO_01139 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFDFGNCO_01140 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HFDFGNCO_01141 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HFDFGNCO_01142 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFDFGNCO_01143 0.0 S L,D-transpeptidase catalytic domain
HFDFGNCO_01144 9.6e-291 sufB O FeS assembly protein SufB
HFDFGNCO_01145 1.4e-234 sufD O FeS assembly protein SufD
HFDFGNCO_01146 1e-142 sufC O FeS assembly ATPase SufC
HFDFGNCO_01147 1e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFDFGNCO_01148 3.4e-97 iscU C SUF system FeS assembly protein, NifU family
HFDFGNCO_01149 2.7e-108 yitW S Iron-sulfur cluster assembly protein
HFDFGNCO_01150 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFDFGNCO_01151 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
HFDFGNCO_01153 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFDFGNCO_01154 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HFDFGNCO_01155 5.9e-208 phoH T PhoH-like protein
HFDFGNCO_01156 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFDFGNCO_01157 4.1e-251 corC S CBS domain
HFDFGNCO_01158 6e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFDFGNCO_01159 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HFDFGNCO_01160 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HFDFGNCO_01161 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HFDFGNCO_01162 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HFDFGNCO_01163 4.2e-269 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_01165 5.1e-224 G Transmembrane secretion effector
HFDFGNCO_01166 5.4e-121 K Bacterial regulatory proteins, tetR family
HFDFGNCO_01167 1.1e-39 nrdH O Glutaredoxin
HFDFGNCO_01168 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
HFDFGNCO_01169 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFDFGNCO_01171 8.2e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFDFGNCO_01172 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HFDFGNCO_01174 2.9e-29 EGP Major facilitator Superfamily
HFDFGNCO_01175 1.3e-25 yhjX EGP Major facilitator Superfamily
HFDFGNCO_01176 3.8e-195 S alpha beta
HFDFGNCO_01177 1.3e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HFDFGNCO_01178 7e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFDFGNCO_01179 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFDFGNCO_01180 1.3e-72 K Acetyltransferase (GNAT) domain
HFDFGNCO_01182 2.5e-227 ilvE 2.6.1.42 E Amino-transferase class IV
HFDFGNCO_01183 1.1e-133 S UPF0126 domain
HFDFGNCO_01184 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
HFDFGNCO_01185 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFDFGNCO_01186 1.5e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
HFDFGNCO_01187 1.4e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HFDFGNCO_01188 6.9e-289 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HFDFGNCO_01189 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HFDFGNCO_01190 8.7e-235 F Psort location CytoplasmicMembrane, score 10.00
HFDFGNCO_01191 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HFDFGNCO_01192 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFDFGNCO_01193 2e-74
HFDFGNCO_01194 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HFDFGNCO_01195 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HFDFGNCO_01196 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HFDFGNCO_01197 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
HFDFGNCO_01198 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFDFGNCO_01199 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HFDFGNCO_01200 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HFDFGNCO_01201 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFDFGNCO_01202 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HFDFGNCO_01203 1.5e-277 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFDFGNCO_01204 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HFDFGNCO_01205 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HFDFGNCO_01206 7.3e-178 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFDFGNCO_01207 4.7e-123 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFDFGNCO_01208 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HFDFGNCO_01209 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HFDFGNCO_01210 8.8e-109 J Acetyltransferase (GNAT) domain
HFDFGNCO_01211 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFDFGNCO_01212 2.5e-219 yxjG_1 E Psort location Cytoplasmic, score 8.87
HFDFGNCO_01213 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HFDFGNCO_01214 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFDFGNCO_01215 1.4e-139 S SdpI/YhfL protein family
HFDFGNCO_01216 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFDFGNCO_01217 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFDFGNCO_01218 4.3e-124 XK27_06785 V ABC transporter
HFDFGNCO_01221 4.3e-63
HFDFGNCO_01222 1.6e-95 M Peptidase family M23
HFDFGNCO_01223 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
HFDFGNCO_01224 4e-268 G ABC transporter substrate-binding protein
HFDFGNCO_01225 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HFDFGNCO_01226 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
HFDFGNCO_01227 3e-107 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HFDFGNCO_01228 9e-72 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFDFGNCO_01229 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFDFGNCO_01230 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFDFGNCO_01231 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HFDFGNCO_01232 1.3e-117
HFDFGNCO_01234 5e-232 XK27_00240 K Fic/DOC family
HFDFGNCO_01235 9.2e-71 pdxH S Pfam:Pyridox_oxidase
HFDFGNCO_01236 2.7e-302 M domain protein
HFDFGNCO_01237 8e-185 3.4.22.70 M Sortase family
HFDFGNCO_01238 2.9e-110 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HFDFGNCO_01239 5.7e-172 corA P CorA-like Mg2+ transporter protein
HFDFGNCO_01240 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
HFDFGNCO_01241 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFDFGNCO_01242 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HFDFGNCO_01243 0.0 comE S Competence protein
HFDFGNCO_01244 8.4e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
HFDFGNCO_01245 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HFDFGNCO_01246 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
HFDFGNCO_01247 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HFDFGNCO_01248 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFDFGNCO_01250 4.6e-119 yoaP E YoaP-like
HFDFGNCO_01251 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFDFGNCO_01252 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
HFDFGNCO_01253 6.7e-72 K MerR family regulatory protein
HFDFGNCO_01254 3e-198 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HFDFGNCO_01255 2.4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFDFGNCO_01256 6e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
HFDFGNCO_01257 2.4e-75 S Psort location CytoplasmicMembrane, score
HFDFGNCO_01258 1e-182 cat P Cation efflux family
HFDFGNCO_01261 1e-98
HFDFGNCO_01262 2.9e-130
HFDFGNCO_01263 5.7e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_01264 9.4e-280 pepC 3.4.22.40 E Peptidase C1-like family
HFDFGNCO_01265 9.8e-183 S IMP dehydrogenase activity
HFDFGNCO_01266 1.9e-300 ybiT S ABC transporter
HFDFGNCO_01267 1.4e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HFDFGNCO_01268 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFDFGNCO_01270 2e-13
HFDFGNCO_01271 7.6e-273 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_01272 4.7e-140 S Domain of unknown function (DUF4194)
HFDFGNCO_01273 0.0 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_01274 3.2e-220 S Psort location Cytoplasmic, score 8.87
HFDFGNCO_01275 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFDFGNCO_01276 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFDFGNCO_01277 6e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HFDFGNCO_01278 1.1e-170 rapZ S Displays ATPase and GTPase activities
HFDFGNCO_01279 1.3e-171 whiA K May be required for sporulation
HFDFGNCO_01280 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HFDFGNCO_01281 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFDFGNCO_01282 2.4e-32 secG U Preprotein translocase SecG subunit
HFDFGNCO_01283 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
HFDFGNCO_01284 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HFDFGNCO_01285 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
HFDFGNCO_01286 5.6e-112 pnuC H Nicotinamide mononucleotide transporter
HFDFGNCO_01287 2.6e-42 nadR H ATPase kinase involved in NAD metabolism
HFDFGNCO_01288 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFDFGNCO_01289 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HFDFGNCO_01290 1e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFDFGNCO_01291 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFDFGNCO_01292 5.1e-158 G Fructosamine kinase
HFDFGNCO_01293 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFDFGNCO_01294 1.6e-156 S PAC2 family
HFDFGNCO_01301 2.5e-08
HFDFGNCO_01302 5.4e-36
HFDFGNCO_01303 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
HFDFGNCO_01304 5.4e-107 K helix_turn_helix, mercury resistance
HFDFGNCO_01305 4.6e-61
HFDFGNCO_01306 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
HFDFGNCO_01307 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HFDFGNCO_01308 0.0 helY L DEAD DEAH box helicase
HFDFGNCO_01309 2.1e-54
HFDFGNCO_01310 0.0 pafB K WYL domain
HFDFGNCO_01311 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HFDFGNCO_01314 5.3e-222 S MvaI/BcnI restriction endonuclease family
HFDFGNCO_01315 1.1e-234 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HFDFGNCO_01320 5.1e-13
HFDFGNCO_01322 0.0 3.2.1.22 G lipolytic protein G-D-S-L family
HFDFGNCO_01323 1.2e-278 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HFDFGNCO_01324 1.8e-108 amyC G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01325 2.5e-125 amyD U Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01326 4.5e-132 msmE G Bacterial extracellular solute-binding protein
HFDFGNCO_01327 8.8e-139 K helix_turn _helix lactose operon repressor
HFDFGNCO_01328 2.8e-290 trxB1 1.8.1.9 C Thioredoxin domain
HFDFGNCO_01329 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HFDFGNCO_01330 1.6e-129 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HFDFGNCO_01331 8.7e-131 S AAA ATPase domain
HFDFGNCO_01332 1.6e-72 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HFDFGNCO_01333 7.4e-39 S SPP1 phage holin
HFDFGNCO_01334 1.4e-89 L DNA integration
HFDFGNCO_01335 1.6e-230 L the current gene model (or a revised gene model) may contain a frame shift
HFDFGNCO_01336 2.4e-212 L Transposase IS116/IS110/IS902 family
HFDFGNCO_01337 7.8e-44 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HFDFGNCO_01338 1.9e-214 dapC E Aminotransferase class I and II
HFDFGNCO_01339 8.3e-59 fdxA C 4Fe-4S binding domain
HFDFGNCO_01340 6.2e-266 E aromatic amino acid transport protein AroP K03293
HFDFGNCO_01341 1.4e-212 murB 1.3.1.98 M Cell wall formation
HFDFGNCO_01342 5.5e-25 rpmG J Ribosomal protein L33
HFDFGNCO_01345 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFDFGNCO_01346 1.6e-147
HFDFGNCO_01347 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HFDFGNCO_01348 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HFDFGNCO_01349 6.1e-30 fmdB S Putative regulatory protein
HFDFGNCO_01350 1.9e-92 flgA NO SAF
HFDFGNCO_01351 7.7e-34
HFDFGNCO_01352 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HFDFGNCO_01353 4.7e-175 T Forkhead associated domain
HFDFGNCO_01354 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFDFGNCO_01355 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFDFGNCO_01356 1.3e-246 pbuO S Permease family
HFDFGNCO_01357 1.8e-143 P Zinc-uptake complex component A periplasmic
HFDFGNCO_01358 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFDFGNCO_01359 4e-168 pstA P Phosphate transport system permease
HFDFGNCO_01360 4.4e-164 pstC P probably responsible for the translocation of the substrate across the membrane
HFDFGNCO_01361 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HFDFGNCO_01362 3.4e-129 KT Transcriptional regulatory protein, C terminal
HFDFGNCO_01363 8.5e-238 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HFDFGNCO_01364 2.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFDFGNCO_01365 3.6e-224 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFDFGNCO_01366 4.1e-217 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFDFGNCO_01367 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
HFDFGNCO_01368 3.8e-58 D nuclear chromosome segregation
HFDFGNCO_01369 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFDFGNCO_01370 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HFDFGNCO_01371 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HFDFGNCO_01372 7e-297 yegQ O Peptidase family U32 C-terminal domain
HFDFGNCO_01373 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HFDFGNCO_01374 0.0 S Predicted membrane protein (DUF2207)
HFDFGNCO_01375 1.7e-91 lemA S LemA family
HFDFGNCO_01376 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HFDFGNCO_01377 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFDFGNCO_01378 2.4e-116
HFDFGNCO_01380 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HFDFGNCO_01381 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFDFGNCO_01383 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HFDFGNCO_01384 0.0 pccB I Carboxyl transferase domain
HFDFGNCO_01385 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HFDFGNCO_01386 2.1e-79 bioY S BioY family
HFDFGNCO_01387 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HFDFGNCO_01388 0.0
HFDFGNCO_01389 5.9e-143 QT PucR C-terminal helix-turn-helix domain
HFDFGNCO_01390 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFDFGNCO_01391 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFDFGNCO_01392 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
HFDFGNCO_01393 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFDFGNCO_01395 2.2e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HFDFGNCO_01396 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFDFGNCO_01397 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFDFGNCO_01398 2.6e-39 rpmA J Ribosomal L27 protein
HFDFGNCO_01399 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFDFGNCO_01400 1.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
HFDFGNCO_01401 1.8e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
HFDFGNCO_01402 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HFDFGNCO_01403 2.5e-270 V Efflux ABC transporter, permease protein
HFDFGNCO_01404 1.9e-127 V ATPases associated with a variety of cellular activities
HFDFGNCO_01405 7.2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFDFGNCO_01406 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFDFGNCO_01407 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFDFGNCO_01408 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HFDFGNCO_01409 1.3e-179 S Auxin Efflux Carrier
HFDFGNCO_01411 3.5e-227 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFDFGNCO_01412 3e-68 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFDFGNCO_01413 1.8e-203 L Transposase
HFDFGNCO_01414 1.1e-23 relB L RelB antitoxin
HFDFGNCO_01415 2e-52 nifJ 1.2.7.1 C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HFDFGNCO_01416 1.8e-23 L Transposase, Mutator family
HFDFGNCO_01419 2.5e-199 S Glucosyl transferase GtrII
HFDFGNCO_01420 2.4e-248 S Polysaccharide pyruvyl transferase
HFDFGNCO_01421 0.0 rgpF M Rhamnan synthesis protein F
HFDFGNCO_01422 4.2e-176 I Acyltransferase family
HFDFGNCO_01423 2.2e-135 1.1.1.339 GM NAD dependent epimerase/dehydratase family
HFDFGNCO_01424 2.6e-149 M Glycosyltransferase like family 2
HFDFGNCO_01425 2.2e-10 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HFDFGNCO_01426 2.8e-65 3.1.4.46 M isomerase activity
HFDFGNCO_01428 7.4e-71 L Transposase, Mutator family
HFDFGNCO_01429 1.7e-153 M Glycosyltransferase like family 2
HFDFGNCO_01430 3.8e-229 glf 5.4.99.9 M UDP-galactopyranose mutase
HFDFGNCO_01431 3e-24 S Domain of unknown function (DUF4190)
HFDFGNCO_01432 6.9e-158 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HFDFGNCO_01433 1.1e-20 S Auxin Efflux Carrier
HFDFGNCO_01434 1.3e-157 K helix_turn_helix isocitrate lyase regulation
HFDFGNCO_01435 4.3e-184 FG ABC transporter substrate-binding protein
HFDFGNCO_01436 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HFDFGNCO_01437 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HFDFGNCO_01438 1.7e-37 K Addiction module
HFDFGNCO_01439 8.8e-53 S Phage derived protein Gp49-like (DUF891)
HFDFGNCO_01440 6.5e-12 S Psort location Extracellular, score 8.82
HFDFGNCO_01441 5.4e-184 K Bacterial regulatory proteins, lacI family
HFDFGNCO_01442 5.3e-156 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01443 1.8e-176 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01444 1.1e-264 G Bacterial extracellular solute-binding protein
HFDFGNCO_01445 8.8e-245 4.2.1.68 M Enolase C-terminal domain-like
HFDFGNCO_01446 2.1e-117
HFDFGNCO_01447 2.7e-80
HFDFGNCO_01448 1.7e-28
HFDFGNCO_01449 2.7e-18 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HFDFGNCO_01450 7.5e-80
HFDFGNCO_01451 2.2e-295 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HFDFGNCO_01452 3.4e-161 rfbJ M Glycosyl transferase family 2
HFDFGNCO_01453 6.7e-186 S Psort location CytoplasmicMembrane, score
HFDFGNCO_01454 2.8e-82 S Acyltransferase family
HFDFGNCO_01455 6.1e-109 rgpC U Transport permease protein
HFDFGNCO_01456 1.2e-174 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HFDFGNCO_01457 1.4e-181 M Glycosyl transferases group 1
HFDFGNCO_01458 1.7e-136 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
HFDFGNCO_01459 7.6e-222 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
HFDFGNCO_01460 5.4e-310 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HFDFGNCO_01461 5.3e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFDFGNCO_01462 4.9e-232 S AAA domain
HFDFGNCO_01463 1.2e-61
HFDFGNCO_01464 1.1e-197 K helix_turn _helix lactose operon repressor
HFDFGNCO_01465 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HFDFGNCO_01466 4.2e-259 EGP Major Facilitator Superfamily
HFDFGNCO_01467 3.7e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFDFGNCO_01468 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFDFGNCO_01469 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HFDFGNCO_01470 3.8e-66 ssb1 L Single-stranded DNA-binding protein
HFDFGNCO_01471 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFDFGNCO_01472 1.7e-70 rplI J Binds to the 23S rRNA
HFDFGNCO_01473 9e-294 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFDFGNCO_01474 5.7e-167 T Pfam Adenylate and Guanylate cyclase catalytic domain
HFDFGNCO_01477 7.6e-12 S zinc-ribbon domain
HFDFGNCO_01478 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HFDFGNCO_01479 4.2e-09 M Protein of unknown function (DUF3152)
HFDFGNCO_01480 9.5e-51 M Protein of unknown function (DUF3152)
HFDFGNCO_01481 5.7e-211 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFDFGNCO_01482 2.5e-80
HFDFGNCO_01483 1.4e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFDFGNCO_01484 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HFDFGNCO_01485 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFDFGNCO_01486 2e-131 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
HFDFGNCO_01487 1.2e-170 rmuC S RmuC family
HFDFGNCO_01488 1e-103 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFDFGNCO_01489 2.4e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HFDFGNCO_01490 6.2e-134 K Psort location Cytoplasmic, score
HFDFGNCO_01491 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFDFGNCO_01492 5.5e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFDFGNCO_01493 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFDFGNCO_01494 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
HFDFGNCO_01495 2.1e-51 S Protein of unknown function (DUF2469)
HFDFGNCO_01496 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HFDFGNCO_01497 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFDFGNCO_01498 1.3e-79 K helix_turn_helix ASNC type
HFDFGNCO_01499 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
HFDFGNCO_01500 0.0 S domain protein
HFDFGNCO_01501 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFDFGNCO_01502 3.5e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFDFGNCO_01503 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFDFGNCO_01504 4.9e-134 KT Transcriptional regulatory protein, C terminal
HFDFGNCO_01505 1.1e-133
HFDFGNCO_01506 3.6e-97 mntP P Probably functions as a manganese efflux pump
HFDFGNCO_01507 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HFDFGNCO_01508 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HFDFGNCO_01509 7.1e-175 M LPXTG-motif cell wall anchor domain protein
HFDFGNCO_01510 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
HFDFGNCO_01511 3.9e-193 yfdV S Membrane transport protein
HFDFGNCO_01512 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFDFGNCO_01514 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFDFGNCO_01515 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HFDFGNCO_01516 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFDFGNCO_01517 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFDFGNCO_01518 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFDFGNCO_01519 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFDFGNCO_01520 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFDFGNCO_01521 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFDFGNCO_01522 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFDFGNCO_01523 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HFDFGNCO_01524 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HFDFGNCO_01525 4e-194
HFDFGNCO_01526 2.7e-180
HFDFGNCO_01527 1.9e-170 trxA2 O Tetratricopeptide repeat
HFDFGNCO_01528 4.7e-122 cyaA 4.6.1.1 S CYTH
HFDFGNCO_01530 7e-60 psp1 3.5.99.10 J Endoribonuclease L-PSP
HFDFGNCO_01531 4.8e-271 mmuP E amino acid
HFDFGNCO_01532 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFDFGNCO_01533 2.9e-298 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFDFGNCO_01534 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
HFDFGNCO_01535 9.2e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFDFGNCO_01536 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HFDFGNCO_01537 2.1e-210 K helix_turn _helix lactose operon repressor
HFDFGNCO_01538 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HFDFGNCO_01539 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HFDFGNCO_01540 3.1e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HFDFGNCO_01541 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HFDFGNCO_01542 0.0 cydD V ABC transporter transmembrane region
HFDFGNCO_01543 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HFDFGNCO_01544 1e-128 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HFDFGNCO_01545 3.5e-239 G Bacterial extracellular solute-binding protein
HFDFGNCO_01546 8.1e-155 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01547 9.1e-168 G ABC transporter permease
HFDFGNCO_01548 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_01549 8.9e-198 K helix_turn _helix lactose operon repressor
HFDFGNCO_01550 2.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
HFDFGNCO_01551 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HFDFGNCO_01552 6.2e-127 L Protein of unknown function (DUF1524)
HFDFGNCO_01553 1.9e-242 T Diguanylate cyclase (GGDEF) domain protein
HFDFGNCO_01554 4.7e-285 EGP Major facilitator Superfamily
HFDFGNCO_01555 2.5e-47
HFDFGNCO_01556 2.2e-182 S Endonuclease/Exonuclease/phosphatase family
HFDFGNCO_01557 1.4e-86 3.1.3.48 T Low molecular weight phosphatase family
HFDFGNCO_01558 5.1e-222 pflA S Protein of unknown function (DUF4012)
HFDFGNCO_01559 1.9e-190 wcoI DM Psort location CytoplasmicMembrane, score
HFDFGNCO_01560 7.7e-20
HFDFGNCO_01561 1.8e-104
HFDFGNCO_01563 4.5e-50 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HFDFGNCO_01564 4.7e-45 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_01565 1.1e-52 L Integrase core domain
HFDFGNCO_01566 3.3e-36 L Integrase core domain
HFDFGNCO_01567 3.1e-43 L Transposase
HFDFGNCO_01568 3.2e-185 rgpAc GT4 M Domain of unknown function (DUF1972)
HFDFGNCO_01569 3.4e-76 GT2 M Glycosyl transferase, group 2 family protein
HFDFGNCO_01570 8.8e-51
HFDFGNCO_01571 2.9e-173 S slime layer polysaccharide biosynthetic process
HFDFGNCO_01572 2.6e-123 IQ Enoyl-(Acyl carrier protein) reductase
HFDFGNCO_01573 3.7e-286 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HFDFGNCO_01574 7.2e-203 cps2J S Polysaccharide biosynthesis protein
HFDFGNCO_01575 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFDFGNCO_01576 8.2e-263 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFDFGNCO_01577 2.5e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFDFGNCO_01578 2.8e-229 S Bacteriophage abortive infection AbiH
HFDFGNCO_01579 1.3e-132 S Psort location CytoplasmicMembrane, score 9.99
HFDFGNCO_01580 6.4e-55 yccF S Inner membrane component domain
HFDFGNCO_01581 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HFDFGNCO_01582 1.3e-145 G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01583 3.6e-163 G PFAM binding-protein-dependent transport systems inner membrane component
HFDFGNCO_01584 6.1e-224 G Bacterial extracellular solute-binding protein
HFDFGNCO_01585 2.1e-185 K helix_turn _helix lactose operon repressor
HFDFGNCO_01586 1.4e-184 K Psort location Cytoplasmic, score
HFDFGNCO_01587 3.3e-269 G Bacterial extracellular solute-binding protein
HFDFGNCO_01588 1.7e-162 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01589 6.5e-148 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01590 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFDFGNCO_01591 2.5e-263 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HFDFGNCO_01593 4.6e-88
HFDFGNCO_01594 4.7e-169 S G5
HFDFGNCO_01595 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HFDFGNCO_01596 3.5e-114 F Domain of unknown function (DUF4916)
HFDFGNCO_01597 3.4e-160 mhpC I Alpha/beta hydrolase family
HFDFGNCO_01598 2.1e-207 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HFDFGNCO_01599 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HFDFGNCO_01600 1.5e-236 S Uncharacterized conserved protein (DUF2183)
HFDFGNCO_01601 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HFDFGNCO_01602 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HFDFGNCO_01603 1.6e-84 J TM2 domain
HFDFGNCO_01604 4.1e-217 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HFDFGNCO_01605 2e-132 glxR K helix_turn_helix, cAMP Regulatory protein
HFDFGNCO_01606 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HFDFGNCO_01607 1.4e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HFDFGNCO_01608 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HFDFGNCO_01609 3.4e-141 glpR K DeoR C terminal sensor domain
HFDFGNCO_01610 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HFDFGNCO_01611 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HFDFGNCO_01612 2.3e-23 lmrB EGP Major facilitator Superfamily
HFDFGNCO_01613 7.1e-43 gcvR T Belongs to the UPF0237 family
HFDFGNCO_01614 7.2e-253 S UPF0210 protein
HFDFGNCO_01615 3.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFDFGNCO_01616 9.3e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HFDFGNCO_01617 6.8e-100
HFDFGNCO_01618 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFDFGNCO_01619 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFDFGNCO_01620 1.6e-86 T Forkhead associated domain
HFDFGNCO_01621 1.7e-78 B Belongs to the OprB family
HFDFGNCO_01622 2.2e-162 3.1.3.16 T Sigma factor PP2C-like phosphatases
HFDFGNCO_01623 0.0 E Transglutaminase-like superfamily
HFDFGNCO_01624 1.6e-219 S Protein of unknown function DUF58
HFDFGNCO_01625 3.5e-226 S ATPase family associated with various cellular activities (AAA)
HFDFGNCO_01626 0.0 S Fibronectin type 3 domain
HFDFGNCO_01627 1.7e-257 KLT Protein tyrosine kinase
HFDFGNCO_01628 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HFDFGNCO_01629 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HFDFGNCO_01630 1.5e-245 G Major Facilitator Superfamily
HFDFGNCO_01631 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFDFGNCO_01632 1.1e-38 csoR S Metal-sensitive transcriptional repressor
HFDFGNCO_01633 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HFDFGNCO_01634 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFDFGNCO_01635 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFDFGNCO_01636 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HFDFGNCO_01637 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFDFGNCO_01638 2.3e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFDFGNCO_01639 2.8e-293 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HFDFGNCO_01640 8.4e-101 yjcS Q Psort location Cytoplasmic, score 8.87
HFDFGNCO_01641 7.4e-52 P Zinc-uptake complex component A periplasmic
HFDFGNCO_01642 5.9e-79 L AAA domain
HFDFGNCO_01643 1.5e-40 parA D VirC1 protein
HFDFGNCO_01648 1.2e-18 S Papain-like cysteine protease AvrRpt2
HFDFGNCO_01649 3.3e-46 S Plasmid encoded RepA protein
HFDFGNCO_01651 7e-20 L AAA domain
HFDFGNCO_01652 0.0 tetP J Elongation factor G, domain IV
HFDFGNCO_01654 2.6e-214 ybiR P Citrate transporter
HFDFGNCO_01655 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFDFGNCO_01656 4.2e-272 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFDFGNCO_01657 1.3e-17 yhdG E aromatic amino acid transport protein AroP K03293
HFDFGNCO_01658 1.4e-34 yhdG E aromatic amino acid transport protein AroP K03293
HFDFGNCO_01659 4.7e-83 T Transcriptional regulatory protein, C terminal
HFDFGNCO_01662 2.5e-60 L Initiator Replication protein
HFDFGNCO_01664 4.9e-49 S MobA/MobL family
HFDFGNCO_01665 4.4e-57 L Psort location Cytoplasmic, score 8.96
HFDFGNCO_01667 2.5e-55 S MobA/MobL family
HFDFGNCO_01669 9.9e-106 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFDFGNCO_01670 1.9e-147 V Efflux ABC transporter, permease protein
HFDFGNCO_01671 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
HFDFGNCO_01673 2.9e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
HFDFGNCO_01674 6.5e-226 M Glycosyl transferase 4-like domain
HFDFGNCO_01675 1.1e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFDFGNCO_01676 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFDFGNCO_01677 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HFDFGNCO_01678 1.9e-36
HFDFGNCO_01679 2.3e-311 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HFDFGNCO_01680 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFDFGNCO_01681 2.4e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFDFGNCO_01682 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
HFDFGNCO_01683 1.6e-247 EGP Major facilitator Superfamily
HFDFGNCO_01684 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HFDFGNCO_01685 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
HFDFGNCO_01686 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HFDFGNCO_01687 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HFDFGNCO_01688 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HFDFGNCO_01689 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HFDFGNCO_01690 2.3e-89 zur P Belongs to the Fur family
HFDFGNCO_01691 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFDFGNCO_01692 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFDFGNCO_01693 1.2e-183 adh3 C Zinc-binding dehydrogenase
HFDFGNCO_01694 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFDFGNCO_01695 1.3e-255 macB_8 V MacB-like periplasmic core domain
HFDFGNCO_01696 5.4e-145 M Conserved repeat domain
HFDFGNCO_01697 3.4e-129 V ATPases associated with a variety of cellular activities
HFDFGNCO_01698 4.3e-75
HFDFGNCO_01699 1.3e-13 S Domain of unknown function (DUF4143)
HFDFGNCO_01700 3.1e-127 XK27_08050 O prohibitin homologues
HFDFGNCO_01701 1.4e-43 XAC3035 O Glutaredoxin
HFDFGNCO_01702 3.2e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFDFGNCO_01703 4.3e-13 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFDFGNCO_01704 4.8e-221 mtnE 2.6.1.83 E Aminotransferase class I and II
HFDFGNCO_01705 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
HFDFGNCO_01706 2.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFDFGNCO_01707 4.3e-158 metQ M NLPA lipoprotein
HFDFGNCO_01708 1.7e-193 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFDFGNCO_01709 5.4e-245 G Transporter major facilitator family protein
HFDFGNCO_01710 0.0 ydcK 3.2.1.23, 5.4.2.9 JM Carbohydrate binding module (family 6)
HFDFGNCO_01711 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HFDFGNCO_01712 1.2e-157 P Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01713 1.1e-135 U Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01714 1.3e-232 G Bacterial extracellular solute-binding protein
HFDFGNCO_01715 3.7e-190 K Periplasmic binding protein domain
HFDFGNCO_01716 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_01717 5.3e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
HFDFGNCO_01718 5.4e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HFDFGNCO_01719 1.8e-119 E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01720 1.9e-110 papP E Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01721 7.7e-101 K acetyltransferase
HFDFGNCO_01725 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
HFDFGNCO_01726 0.0 KLT Protein tyrosine kinase
HFDFGNCO_01727 2.4e-149 O Thioredoxin
HFDFGNCO_01729 1.8e-31 S G5
HFDFGNCO_01730 5.7e-89 S G5
HFDFGNCO_01731 9e-167 tnpX L Psort location Cytoplasmic, score 8.87
HFDFGNCO_01732 5e-40 S Psort location Cytoplasmic, score
HFDFGNCO_01733 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFDFGNCO_01734 1.7e-63 I Sterol carrier protein
HFDFGNCO_01735 1.4e-41 S Protein of unknown function (DUF3073)
HFDFGNCO_01736 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFDFGNCO_01737 2.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFDFGNCO_01738 0.0 yjjP S Threonine/Serine exporter, ThrE
HFDFGNCO_01739 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HFDFGNCO_01740 1.6e-37
HFDFGNCO_01741 5.3e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HFDFGNCO_01742 1.5e-239 ytfL P Transporter associated domain
HFDFGNCO_01743 2e-188 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFDFGNCO_01744 3.1e-101 S Protein of unknown function DUF45
HFDFGNCO_01748 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFDFGNCO_01749 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFDFGNCO_01750 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
HFDFGNCO_01751 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFDFGNCO_01752 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFDFGNCO_01753 6.2e-90 S Protein of unknown function (DUF721)
HFDFGNCO_01754 1.1e-234 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFDFGNCO_01755 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFDFGNCO_01756 2.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFDFGNCO_01757 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFDFGNCO_01758 1.5e-43 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFDFGNCO_01759 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
HFDFGNCO_01760 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
HFDFGNCO_01761 1.4e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFDFGNCO_01762 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HFDFGNCO_01763 1.5e-202 parB K Belongs to the ParB family
HFDFGNCO_01764 3.5e-191 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFDFGNCO_01765 7e-14 S Psort location Extracellular, score 8.82
HFDFGNCO_01767 1.8e-83 tetP J elongation factor G
HFDFGNCO_01768 1.4e-244 tetP J elongation factor G
HFDFGNCO_01769 4.8e-19 S Maff2 family
HFDFGNCO_01770 1.7e-37
HFDFGNCO_01771 0.0 U Psort location Cytoplasmic, score
HFDFGNCO_01772 5.9e-77 S Protein of unknown function (DUF3801)
HFDFGNCO_01773 3e-36 S Domain of unknown function (DUF5348)
HFDFGNCO_01774 1.2e-187 L Psort location Cytoplasmic, score 8.87
HFDFGNCO_01775 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HFDFGNCO_01776 2e-12 S Domain of unknown function (DUF4143)
HFDFGNCO_01777 0.0 murJ KLT MviN-like protein
HFDFGNCO_01778 4.1e-306 murJ KLT MviN-like protein
HFDFGNCO_01779 0.0 M Conserved repeat domain
HFDFGNCO_01780 6.3e-122 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HFDFGNCO_01781 8.5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HFDFGNCO_01782 2.6e-109 S LytR cell envelope-related transcriptional attenuator
HFDFGNCO_01783 9.6e-169 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFDFGNCO_01784 1.7e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFDFGNCO_01785 4e-39 S G5
HFDFGNCO_01786 1.9e-144 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HFDFGNCO_01787 2.2e-173 T GHKL domain
HFDFGNCO_01788 2.5e-57 T GHKL domain
HFDFGNCO_01789 1.4e-130 KT LytTr DNA-binding domain
HFDFGNCO_01790 5.6e-272 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
HFDFGNCO_01791 3.4e-307 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N terminal domain
HFDFGNCO_01792 3.2e-63
HFDFGNCO_01793 0.0 3.2.1.23 G Domain of unknown function (DUF4982)
HFDFGNCO_01794 1e-110 S Psort location CytoplasmicMembrane, score
HFDFGNCO_01795 5.1e-60 S Protein of unknown function (DUF4235)
HFDFGNCO_01796 2.9e-136 G Phosphoglycerate mutase family
HFDFGNCO_01797 2.3e-31 K purine nucleotide biosynthetic process
HFDFGNCO_01798 2e-68 K Psort location Cytoplasmic, score
HFDFGNCO_01799 6.1e-199 K Psort location Cytoplasmic, score
HFDFGNCO_01800 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HFDFGNCO_01801 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HFDFGNCO_01802 7.3e-115 S Protein of unknown function, DUF624
HFDFGNCO_01803 2.1e-196 K Periplasmic binding protein domain
HFDFGNCO_01804 1.7e-289 3.2.1.26 GH32 G Glycosyl hydrolases family 32
HFDFGNCO_01805 1.3e-251 amyE G Bacterial extracellular solute-binding protein
HFDFGNCO_01806 1.2e-09 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFDFGNCO_01807 1.1e-184 K Psort location Cytoplasmic, score
HFDFGNCO_01808 2e-152 rafG G ABC transporter permease
HFDFGNCO_01809 8.2e-138 msmF G Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01810 8.2e-185 K Psort location Cytoplasmic, score
HFDFGNCO_01811 3.2e-253 amyE G Bacterial extracellular solute-binding protein
HFDFGNCO_01812 3.5e-226 M Protein of unknown function (DUF2961)
HFDFGNCO_01813 3.9e-267 amyE G Bacterial extracellular solute-binding protein
HFDFGNCO_01814 4.9e-55 S HAD-hyrolase-like
HFDFGNCO_01815 2.6e-153 S AAA domain
HFDFGNCO_01816 2.7e-126 S membrane transporter protein
HFDFGNCO_01817 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HFDFGNCO_01818 0.0 dnaK O Heat shock 70 kDa protein
HFDFGNCO_01819 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFDFGNCO_01820 1.5e-162 dnaJ1 O DnaJ molecular chaperone homology domain
HFDFGNCO_01821 4.5e-115 hspR K transcriptional regulator, MerR family
HFDFGNCO_01822 9.5e-46
HFDFGNCO_01823 3.3e-129 S HAD hydrolase, family IA, variant 3
HFDFGNCO_01825 5.8e-126 dedA S SNARE associated Golgi protein
HFDFGNCO_01826 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
HFDFGNCO_01827 6.1e-191 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFDFGNCO_01828 3.2e-73
HFDFGNCO_01829 2.1e-105
HFDFGNCO_01830 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFDFGNCO_01831 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFDFGNCO_01833 4.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HFDFGNCO_01834 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_01835 1.1e-97 T AAA domain
HFDFGNCO_01837 1.7e-229 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HFDFGNCO_01838 5e-173 S Domain of unknown function (DUF4928)
HFDFGNCO_01840 8.4e-137 L HNH endonuclease
HFDFGNCO_01841 3e-277 cysB 4.2.1.22 EGP Major facilitator Superfamily
HFDFGNCO_01842 1.6e-120
HFDFGNCO_01844 2.4e-179 MA20_14895 S Conserved hypothetical protein 698
HFDFGNCO_01845 3.2e-226 C Na H antiporter family protein
HFDFGNCO_01846 1.7e-173 korD 1.2.7.3 C Domain of unknown function (DUF362)
HFDFGNCO_01847 1.4e-112 2.7.1.48 F uridine kinase
HFDFGNCO_01848 1.9e-93 S ECF transporter, substrate-specific component
HFDFGNCO_01849 6.8e-145 S Sulfite exporter TauE/SafE
HFDFGNCO_01850 1.5e-135 K helix_turn_helix, arabinose operon control protein
HFDFGNCO_01851 4.9e-156 3.1.3.73 G Phosphoglycerate mutase family
HFDFGNCO_01852 3.8e-227 rutG F Permease family
HFDFGNCO_01853 6e-126 S Enoyl-(Acyl carrier protein) reductase
HFDFGNCO_01854 1.2e-278 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HFDFGNCO_01855 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
HFDFGNCO_01856 6.6e-140 ybbL V ATPases associated with a variety of cellular activities
HFDFGNCO_01857 2.2e-241 S Putative esterase
HFDFGNCO_01858 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HFDFGNCO_01859 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFDFGNCO_01860 6.3e-148 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFDFGNCO_01861 3.1e-236 patB 4.4.1.8 E Aminotransferase, class I II
HFDFGNCO_01862 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFDFGNCO_01863 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
HFDFGNCO_01864 1.3e-145 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HFDFGNCO_01865 3.6e-310 EGP Major Facilitator Superfamily
HFDFGNCO_01866 1e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFDFGNCO_01867 1.3e-87 M Protein of unknown function (DUF3737)
HFDFGNCO_01868 1.4e-142 azlC E AzlC protein
HFDFGNCO_01869 5.5e-53 azlD E Branched-chain amino acid transport protein (AzlD)
HFDFGNCO_01870 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
HFDFGNCO_01871 6.2e-40 ybdD S Selenoprotein, putative
HFDFGNCO_01872 4.7e-180 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HFDFGNCO_01873 0.0 S Uncharacterised protein family (UPF0182)
HFDFGNCO_01874 5.1e-101 2.3.1.183 M Acetyltransferase (GNAT) domain
HFDFGNCO_01875 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFDFGNCO_01876 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFDFGNCO_01877 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFDFGNCO_01878 2e-71 divIC D Septum formation initiator
HFDFGNCO_01879 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HFDFGNCO_01880 3.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HFDFGNCO_01882 3.5e-92
HFDFGNCO_01883 1.7e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HFDFGNCO_01884 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HFDFGNCO_01885 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFDFGNCO_01886 2.7e-144 yplQ S Haemolysin-III related
HFDFGNCO_01887 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFDFGNCO_01888 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HFDFGNCO_01889 0.0 D FtsK/SpoIIIE family
HFDFGNCO_01890 6.2e-171 K Cell envelope-related transcriptional attenuator domain
HFDFGNCO_01892 3.2e-219 K Cell envelope-related transcriptional attenuator domain
HFDFGNCO_01893 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HFDFGNCO_01894 0.0 S Glycosyl transferase, family 2
HFDFGNCO_01895 8.7e-223
HFDFGNCO_01896 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HFDFGNCO_01897 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HFDFGNCO_01898 8.5e-139 ctsW S Phosphoribosyl transferase domain
HFDFGNCO_01899 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFDFGNCO_01900 2e-129 T Response regulator receiver domain protein
HFDFGNCO_01901 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFDFGNCO_01902 3e-102 carD K CarD-like/TRCF domain
HFDFGNCO_01903 1.7e-87 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HFDFGNCO_01904 2.3e-140 znuB U ABC 3 transport family
HFDFGNCO_01905 2e-160 znuC P ATPases associated with a variety of cellular activities
HFDFGNCO_01906 1.8e-174 P Zinc-uptake complex component A periplasmic
HFDFGNCO_01907 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFDFGNCO_01908 8.3e-255 rpsA J Ribosomal protein S1
HFDFGNCO_01909 1.5e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFDFGNCO_01910 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFDFGNCO_01911 8.8e-176 terC P Integral membrane protein, TerC family
HFDFGNCO_01912 5.6e-305 pyk 2.7.1.40 G Pyruvate kinase
HFDFGNCO_01914 1.1e-41 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFDFGNCO_01915 2.5e-24 relB L RelB antitoxin
HFDFGNCO_01917 1.3e-101 rbsR K helix_turn _helix lactose operon repressor
HFDFGNCO_01918 1.8e-200 malE G Bacterial extracellular solute-binding protein
HFDFGNCO_01919 1.6e-147 U Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01920 3.5e-139 U Binding-protein-dependent transport system inner membrane component
HFDFGNCO_01921 1.9e-196 bglA 3.2.1.21 G Glycosyl hydrolase family 1
HFDFGNCO_01922 2.4e-91 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
HFDFGNCO_01923 1e-159 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HFDFGNCO_01924 9.3e-117 pdtaR T Response regulator receiver domain protein
HFDFGNCO_01925 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFDFGNCO_01926 4.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HFDFGNCO_01927 1.5e-123 3.6.1.13 L NUDIX domain
HFDFGNCO_01928 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HFDFGNCO_01929 5.9e-211 ykiI
HFDFGNCO_01931 2.5e-138 L Phage integrase family
HFDFGNCO_01932 6.6e-69
HFDFGNCO_01933 5.5e-23
HFDFGNCO_01934 1.3e-67 rlfA S Protein of unknown function (DUF3800)
HFDFGNCO_01935 3.5e-59
HFDFGNCO_01936 6.4e-35
HFDFGNCO_01938 6.2e-55
HFDFGNCO_01939 3.2e-80 K BRO family, N-terminal domain
HFDFGNCO_01942 5.2e-34
HFDFGNCO_01943 3.1e-21
HFDFGNCO_01946 6.9e-24
HFDFGNCO_01948 1.7e-33 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HFDFGNCO_01949 3.8e-12
HFDFGNCO_01951 6.3e-09
HFDFGNCO_01953 3.4e-92
HFDFGNCO_01954 1.2e-36 L single-stranded DNA binding
HFDFGNCO_01955 7.1e-288 S Bifunctional DNA primase/polymerase, N-terminal
HFDFGNCO_01957 3.8e-14
HFDFGNCO_01958 3.3e-112 J tRNA 5'-leader removal
HFDFGNCO_01959 4.1e-53 V HNH nucleases
HFDFGNCO_01960 8.7e-15 S HNH endonuclease
HFDFGNCO_01961 1.3e-30
HFDFGNCO_01962 7.6e-229 S Terminase
HFDFGNCO_01963 2.4e-257 S Phage portal protein, SPP1 Gp6-like
HFDFGNCO_01964 2.2e-46
HFDFGNCO_01966 6.8e-74
HFDFGNCO_01967 6.3e-149 V Phage capsid family
HFDFGNCO_01969 2.3e-66 S Phage protein Gp19/Gp15/Gp42
HFDFGNCO_01970 5.3e-45
HFDFGNCO_01971 8.4e-32
HFDFGNCO_01972 1.7e-61
HFDFGNCO_01973 6.9e-110
HFDFGNCO_01974 7.1e-57
HFDFGNCO_01976 6.3e-116 S phage tail tape measure protein
HFDFGNCO_01977 2.3e-116
HFDFGNCO_01978 1.2e-114 S Psort location Cytoplasmic, score
HFDFGNCO_01980 3.3e-07 S Psort location Cytoplasmic, score
HFDFGNCO_01982 4.9e-68
HFDFGNCO_01984 4.8e-33
HFDFGNCO_01985 3.5e-34
HFDFGNCO_01987 3.6e-149 L DNA integration
HFDFGNCO_01988 9.1e-18
HFDFGNCO_01989 6e-193 M Glycosyl hydrolases family 25
HFDFGNCO_01990 1.2e-28 S Putative phage holin Dp-1
HFDFGNCO_01991 2.2e-254 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFDFGNCO_01992 5.1e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFDFGNCO_01993 1.2e-207 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_01994 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HFDFGNCO_01995 9.2e-25 S Polyketide cyclase / dehydrase and lipid transport
HFDFGNCO_01996 4e-53 K TfoX N-terminal domain
HFDFGNCO_01997 5.9e-123 V ABC transporter transmembrane region
HFDFGNCO_01998 2.7e-127 rbsR K helix_turn _helix lactose operon repressor
HFDFGNCO_01999 4.1e-43 K acetyltransferase
HFDFGNCO_02000 2.6e-105 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HFDFGNCO_02001 4.7e-162 dcuD C C4-dicarboxylate anaerobic carrier
HFDFGNCO_02002 1.2e-07 T AAA domain
HFDFGNCO_02003 4.3e-143 T AAA domain
HFDFGNCO_02004 3.9e-27
HFDFGNCO_02005 5e-64 L Phage integrase, N-terminal SAM-like domain
HFDFGNCO_02007 4.6e-92 EGP Major facilitator Superfamily
HFDFGNCO_02008 3.7e-48 EGP Major facilitator Superfamily
HFDFGNCO_02009 8.3e-31 yuxJ EGP Major facilitator Superfamily
HFDFGNCO_02010 2.8e-91 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFDFGNCO_02011 5.7e-294 clcA P Voltage gated chloride channel
HFDFGNCO_02012 1.9e-225 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFDFGNCO_02013 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFDFGNCO_02014 0.0 pip S YhgE Pip domain protein
HFDFGNCO_02015 0.0 pip S YhgE Pip domain protein
HFDFGNCO_02016 1.2e-169 yddG EG EamA-like transporter family
HFDFGNCO_02017 3.2e-65 K Helix-turn-helix XRE-family like proteins
HFDFGNCO_02019 1.2e-162 htpX O Belongs to the peptidase M48B family
HFDFGNCO_02020 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HFDFGNCO_02021 7.9e-188 ansA 3.5.1.1 EJ Asparaginase
HFDFGNCO_02022 0.0 cadA P E1-E2 ATPase
HFDFGNCO_02023 7.7e-288 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HFDFGNCO_02024 9.4e-269 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFDFGNCO_02027 1.5e-159 yicL EG EamA-like transporter family
HFDFGNCO_02028 2.3e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
HFDFGNCO_02029 7.1e-113 K helix_turn_helix, Lux Regulon
HFDFGNCO_02030 6.3e-82 2.7.13.3 T Histidine kinase
HFDFGNCO_02031 2.5e-116 2.7.13.3 T Histidine kinase
HFDFGNCO_02032 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HFDFGNCO_02033 1.2e-131 fhaA T Protein of unknown function (DUF2662)
HFDFGNCO_02034 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HFDFGNCO_02035 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HFDFGNCO_02036 8.5e-271 rodA D Belongs to the SEDS family
HFDFGNCO_02037 2.7e-266 pbpA M penicillin-binding protein
HFDFGNCO_02038 5.8e-177 T Protein tyrosine kinase
HFDFGNCO_02039 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HFDFGNCO_02040 1.3e-116 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HFDFGNCO_02041 6.7e-209 srtA 3.4.22.70 M Sortase family
HFDFGNCO_02042 6.8e-142 S Bacterial protein of unknown function (DUF881)
HFDFGNCO_02043 3.1e-57 crgA D Involved in cell division
HFDFGNCO_02044 1.9e-240 L ribosomal rna small subunit methyltransferase
HFDFGNCO_02045 2.8e-148 gluP 3.4.21.105 S Rhomboid family
HFDFGNCO_02046 1.5e-35
HFDFGNCO_02047 3.2e-155 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFDFGNCO_02048 1.5e-124
HFDFGNCO_02049 3.9e-34 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HFDFGNCO_02050 2.1e-35 metY 2.5.1.49 E Aminotransferase class-V
HFDFGNCO_02051 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
HFDFGNCO_02052 1.9e-305 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HFDFGNCO_02053 6.9e-150 P Cobalt transport protein
HFDFGNCO_02054 2.4e-192 K helix_turn_helix ASNC type
HFDFGNCO_02055 1.9e-98 V ABC transporter, ATP-binding protein
HFDFGNCO_02056 2.2e-36 MV MacB-like periplasmic core domain
HFDFGNCO_02057 2e-33 MV MacB-like periplasmic core domain
HFDFGNCO_02058 1e-117 MV MacB-like periplasmic core domain
HFDFGNCO_02059 2e-148 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFDFGNCO_02060 7.4e-122 EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_02061 6.3e-107 EP Binding-protein-dependent transport system inner membrane component
HFDFGNCO_02062 6.9e-124 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
HFDFGNCO_02063 9.7e-120 dppF E ABC transporter
HFDFGNCO_02064 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HFDFGNCO_02066 0.0 G Psort location Cytoplasmic, score 8.87
HFDFGNCO_02067 7.7e-232 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HFDFGNCO_02068 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HFDFGNCO_02069 4.3e-296 CE10 I Belongs to the type-B carboxylesterase lipase family
HFDFGNCO_02071 1.7e-222 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFDFGNCO_02072 1.7e-169 M Bacterial capsule synthesis protein PGA_cap
HFDFGNCO_02073 1.3e-54 M Bacterial capsule synthesis protein PGA_cap
HFDFGNCO_02074 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFDFGNCO_02075 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HFDFGNCO_02076 3.1e-122
HFDFGNCO_02077 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HFDFGNCO_02078 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFDFGNCO_02079 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
HFDFGNCO_02080 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HFDFGNCO_02081 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFDFGNCO_02082 1e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HFDFGNCO_02083 4.2e-239 EGP Major facilitator Superfamily
HFDFGNCO_02084 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
HFDFGNCO_02085 4.7e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
HFDFGNCO_02086 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFDFGNCO_02087 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HFDFGNCO_02088 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFDFGNCO_02089 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
HFDFGNCO_02090 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFDFGNCO_02091 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFDFGNCO_02092 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFDFGNCO_02093 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFDFGNCO_02094 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFDFGNCO_02095 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFDFGNCO_02096 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HFDFGNCO_02097 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)