ORF_ID e_value Gene_name EC_number CAZy COGs Description
EECMNDAG_00001 1.7e-91 lemA S LemA family
EECMNDAG_00002 0.0 S Predicted membrane protein (DUF2207)
EECMNDAG_00003 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
EECMNDAG_00004 7e-297 yegQ O Peptidase family U32 C-terminal domain
EECMNDAG_00005 1.4e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
EECMNDAG_00006 5.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EECMNDAG_00007 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EECMNDAG_00008 3.8e-58 D nuclear chromosome segregation
EECMNDAG_00009 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
EECMNDAG_00010 5.7e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EECMNDAG_00011 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EECMNDAG_00012 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EECMNDAG_00013 8.2e-220 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
EECMNDAG_00014 3.4e-129 KT Transcriptional regulatory protein, C terminal
EECMNDAG_00015 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
EECMNDAG_00016 3.4e-164 pstC P probably responsible for the translocation of the substrate across the membrane
EECMNDAG_00017 4e-168 pstA P Phosphate transport system permease
EECMNDAG_00018 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EECMNDAG_00019 9.5e-145 P Zinc-uptake complex component A periplasmic
EECMNDAG_00020 1.3e-246 pbuO S Permease family
EECMNDAG_00021 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EECMNDAG_00022 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EECMNDAG_00023 1.6e-175 T Forkhead associated domain
EECMNDAG_00024 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
EECMNDAG_00025 4.8e-36
EECMNDAG_00026 6.5e-93 flgA NO SAF
EECMNDAG_00027 1.3e-29 fmdB S Putative regulatory protein
EECMNDAG_00028 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
EECMNDAG_00029 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
EECMNDAG_00030 1.6e-147
EECMNDAG_00031 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EECMNDAG_00035 5.5e-25 rpmG J Ribosomal protein L33
EECMNDAG_00036 1.2e-203 murB 1.3.1.98 M Cell wall formation
EECMNDAG_00037 2.8e-266 E aromatic amino acid transport protein AroP K03293
EECMNDAG_00038 8.3e-59 fdxA C 4Fe-4S binding domain
EECMNDAG_00039 3.9e-215 dapC E Aminotransferase class I and II
EECMNDAG_00040 2.9e-36 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
EECMNDAG_00041 0.0 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00042 2.2e-231 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
EECMNDAG_00043 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
EECMNDAG_00044 4.3e-296 CE10 I Belongs to the type-B carboxylesterase lipase family
EECMNDAG_00046 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EECMNDAG_00047 6.1e-252 M Bacterial capsule synthesis protein PGA_cap
EECMNDAG_00048 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EECMNDAG_00049 1.8e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
EECMNDAG_00050 6.9e-122
EECMNDAG_00051 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EECMNDAG_00052 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EECMNDAG_00053 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
EECMNDAG_00054 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_00055 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EECMNDAG_00056 2.1e-213 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
EECMNDAG_00057 3.1e-234 EGP Major facilitator Superfamily
EECMNDAG_00058 6.8e-195 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
EECMNDAG_00059 2.1e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
EECMNDAG_00060 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EECMNDAG_00061 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
EECMNDAG_00062 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EECMNDAG_00063 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
EECMNDAG_00064 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EECMNDAG_00065 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EECMNDAG_00066 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EECMNDAG_00067 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EECMNDAG_00068 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EECMNDAG_00069 4.9e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EECMNDAG_00070 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
EECMNDAG_00071 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EECMNDAG_00072 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EECMNDAG_00073 1.9e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EECMNDAG_00074 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EECMNDAG_00075 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EECMNDAG_00076 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EECMNDAG_00077 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EECMNDAG_00078 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EECMNDAG_00079 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EECMNDAG_00080 3.4e-25 rpmD J Ribosomal protein L30p/L7e
EECMNDAG_00081 9.8e-74 rplO J binds to the 23S rRNA
EECMNDAG_00082 9.9e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EECMNDAG_00083 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EECMNDAG_00084 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EECMNDAG_00085 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EECMNDAG_00086 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EECMNDAG_00087 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EECMNDAG_00088 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EECMNDAG_00089 1.3e-66 rplQ J Ribosomal protein L17
EECMNDAG_00090 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EECMNDAG_00092 4.4e-102
EECMNDAG_00093 6.1e-191 nusA K Participates in both transcription termination and antitermination
EECMNDAG_00094 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EECMNDAG_00095 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EECMNDAG_00096 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EECMNDAG_00097 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
EECMNDAG_00098 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EECMNDAG_00099 3.8e-108
EECMNDAG_00101 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EECMNDAG_00102 2.7e-41 L Transposase
EECMNDAG_00103 1.8e-146 tnp7109-21 L Integrase core domain
EECMNDAG_00104 3.4e-189 tkt 2.2.1.1 H Belongs to the transketolase family
EECMNDAG_00105 1e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EECMNDAG_00106 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EECMNDAG_00107 5.1e-158 G Fructosamine kinase
EECMNDAG_00108 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EECMNDAG_00109 1.6e-156 S PAC2 family
EECMNDAG_00114 5.6e-94 L cog cog1662
EECMNDAG_00115 9e-21 JD73_08040 L Belongs to the 'phage' integrase family
EECMNDAG_00116 8.7e-248 S zinc finger
EECMNDAG_00117 7.5e-71 S Bacterial PH domain
EECMNDAG_00118 1.5e-76
EECMNDAG_00119 8.4e-201 V Domain of unknown function (DUF3427)
EECMNDAG_00120 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
EECMNDAG_00121 2.8e-185 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
EECMNDAG_00122 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EECMNDAG_00123 4.3e-233 aspB E Aminotransferase class-V
EECMNDAG_00124 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EECMNDAG_00125 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
EECMNDAG_00126 1.7e-23
EECMNDAG_00127 3.5e-43 V ATPases associated with a variety of cellular activities
EECMNDAG_00129 1.2e-197 S Endonuclease/Exonuclease/phosphatase family
EECMNDAG_00131 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EECMNDAG_00132 2.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EECMNDAG_00133 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
EECMNDAG_00134 2.4e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EECMNDAG_00135 1.5e-155 hgdC I BadF/BadG/BcrA/BcrD ATPase family
EECMNDAG_00136 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
EECMNDAG_00137 1.6e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
EECMNDAG_00138 4.2e-115 K Bacterial regulatory proteins, tetR family
EECMNDAG_00139 1.2e-74 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
EECMNDAG_00140 5.2e-95 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
EECMNDAG_00141 5.9e-112 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EECMNDAG_00142 5e-57 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EECMNDAG_00143 0.0 cydD V ABC transporter transmembrane region
EECMNDAG_00144 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EECMNDAG_00145 8.8e-128 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EECMNDAG_00146 9.1e-240 G Bacterial extracellular solute-binding protein
EECMNDAG_00147 5.8e-32 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_00148 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00149 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
EECMNDAG_00150 2.2e-246 G Bacterial extracellular solute-binding protein
EECMNDAG_00151 9.1e-275 G Bacterial extracellular solute-binding protein
EECMNDAG_00152 2e-183 K helix_turn _helix lactose operon repressor
EECMNDAG_00153 5.5e-195 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
EECMNDAG_00154 5.7e-104 K Bacterial regulatory proteins, tetR family
EECMNDAG_00155 7.5e-239 G Transporter major facilitator family protein
EECMNDAG_00156 2.3e-234 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
EECMNDAG_00157 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
EECMNDAG_00158 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
EECMNDAG_00159 5.2e-113 K Bacterial regulatory proteins, tetR family
EECMNDAG_00160 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
EECMNDAG_00161 1.8e-220 lmrB U Major Facilitator Superfamily
EECMNDAG_00162 6.8e-118 K Periplasmic binding protein domain
EECMNDAG_00163 4.4e-215 EGP Major facilitator Superfamily
EECMNDAG_00164 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
EECMNDAG_00165 3.2e-181 G Transporter major facilitator family protein
EECMNDAG_00166 7.2e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EECMNDAG_00167 5.1e-107 K Bacterial regulatory proteins, tetR family
EECMNDAG_00168 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
EECMNDAG_00169 1.4e-101 K MarR family
EECMNDAG_00170 0.0 V ABC transporter, ATP-binding protein
EECMNDAG_00171 0.0 V ABC transporter transmembrane region
EECMNDAG_00172 2.1e-36 rpsA J Ribosomal protein S1
EECMNDAG_00173 7.7e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EECMNDAG_00174 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EECMNDAG_00175 5.4e-14 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EECMNDAG_00176 2.8e-157 terC P Integral membrane protein, TerC family
EECMNDAG_00177 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
EECMNDAG_00179 2e-52 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EECMNDAG_00180 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
EECMNDAG_00181 5.2e-128 yebC K transcriptional regulatory protein
EECMNDAG_00182 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EECMNDAG_00183 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EECMNDAG_00184 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EECMNDAG_00185 1.8e-50 yajC U Preprotein translocase subunit
EECMNDAG_00186 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EECMNDAG_00187 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EECMNDAG_00188 0.0 helY L DEAD DEAH box helicase
EECMNDAG_00189 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
EECMNDAG_00190 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
EECMNDAG_00191 4.6e-61
EECMNDAG_00192 9.7e-112 K helix_turn_helix, mercury resistance
EECMNDAG_00193 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
EECMNDAG_00194 5.4e-36
EECMNDAG_00195 2.5e-08
EECMNDAG_00198 6.2e-134 K Psort location Cytoplasmic, score
EECMNDAG_00199 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
EECMNDAG_00200 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EECMNDAG_00201 6.3e-169 rmuC S RmuC family
EECMNDAG_00202 1.8e-135 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
EECMNDAG_00203 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EECMNDAG_00204 2.3e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
EECMNDAG_00205 1.4e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EECMNDAG_00206 2.5e-80
EECMNDAG_00207 2.4e-209 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
EECMNDAG_00208 1.7e-53 M Protein of unknown function (DUF3152)
EECMNDAG_00209 4.2e-09 M Protein of unknown function (DUF3152)
EECMNDAG_00210 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EECMNDAG_00211 4.2e-10 S zinc-ribbon domain
EECMNDAG_00214 2.2e-166 T Pfam Adenylate and Guanylate cyclase catalytic domain
EECMNDAG_00215 2.4e-291 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EECMNDAG_00216 1.7e-70 rplI J Binds to the 23S rRNA
EECMNDAG_00217 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EECMNDAG_00218 9.7e-70 ssb1 L Single-stranded DNA-binding protein
EECMNDAG_00219 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EECMNDAG_00220 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EECMNDAG_00221 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EECMNDAG_00222 1.4e-259 EGP Major Facilitator Superfamily
EECMNDAG_00223 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EECMNDAG_00224 1.1e-197 K helix_turn _helix lactose operon repressor
EECMNDAG_00225 1.2e-61
EECMNDAG_00226 6.9e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EECMNDAG_00227 2.6e-39 xylR GK ROK family
EECMNDAG_00229 1.5e-35 rpmE J Binds the 23S rRNA
EECMNDAG_00230 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EECMNDAG_00231 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EECMNDAG_00232 7.8e-219 livK E Receptor family ligand binding region
EECMNDAG_00233 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
EECMNDAG_00234 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
EECMNDAG_00235 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
EECMNDAG_00236 1.9e-124 livF E ATPases associated with a variety of cellular activities
EECMNDAG_00237 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
EECMNDAG_00238 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
EECMNDAG_00239 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EECMNDAG_00240 2.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
EECMNDAG_00241 4.6e-160 supH S Sucrose-6F-phosphate phosphohydrolase
EECMNDAG_00242 2.5e-269 recD2 3.6.4.12 L PIF1-like helicase
EECMNDAG_00243 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EECMNDAG_00244 6.8e-98 L Single-strand binding protein family
EECMNDAG_00245 0.0 pepO 3.4.24.71 O Peptidase family M13
EECMNDAG_00246 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
EECMNDAG_00247 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
EECMNDAG_00248 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
EECMNDAG_00249 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EECMNDAG_00250 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EECMNDAG_00251 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
EECMNDAG_00252 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
EECMNDAG_00253 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
EECMNDAG_00254 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EECMNDAG_00255 1.4e-26
EECMNDAG_00256 1.2e-140 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00257 1.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
EECMNDAG_00258 6.9e-119 S IMP dehydrogenase activity
EECMNDAG_00259 1.2e-40 S IMP dehydrogenase activity
EECMNDAG_00260 1.9e-300 ybiT S ABC transporter
EECMNDAG_00261 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
EECMNDAG_00262 3.1e-15 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EECMNDAG_00263 2.5e-20 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_00264 9e-118 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_00265 6.8e-104 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_00266 2.1e-88
EECMNDAG_00267 5.6e-170 S G5
EECMNDAG_00268 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
EECMNDAG_00269 3.5e-114 F Domain of unknown function (DUF4916)
EECMNDAG_00270 1.7e-92 mhpC I Alpha/beta hydrolase family
EECMNDAG_00271 1.6e-29 L Escherichia coli O157 H7 ortholog
EECMNDAG_00272 2.3e-56
EECMNDAG_00273 7e-138 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00274 3.2e-220 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00275 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EECMNDAG_00276 9.2e-294 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00277 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
EECMNDAG_00278 1.8e-83 K Cro/C1-type HTH DNA-binding domain
EECMNDAG_00279 0.0 S Psort location CytoplasmicMembrane, score 9.99
EECMNDAG_00280 6.2e-241 V ABC transporter permease
EECMNDAG_00281 2.4e-156 V ABC transporter
EECMNDAG_00282 5.1e-150 T HD domain
EECMNDAG_00283 1e-167 S Glutamine amidotransferase domain
EECMNDAG_00284 0.0 kup P Transport of potassium into the cell
EECMNDAG_00285 2.2e-184 tatD L TatD related DNase
EECMNDAG_00286 0.0 G Alpha-L-arabinofuranosidase C-terminus
EECMNDAG_00287 6.6e-233 G Alpha galactosidase A
EECMNDAG_00288 6.6e-221 K helix_turn _helix lactose operon repressor
EECMNDAG_00289 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00290 8e-126
EECMNDAG_00291 0.0 yknV V ABC transporter
EECMNDAG_00292 0.0 mdlA2 V ABC transporter
EECMNDAG_00293 1.1e-214 lipA I Hydrolase, alpha beta domain protein
EECMNDAG_00294 5e-27 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00295 3.8e-156 I alpha/beta hydrolase fold
EECMNDAG_00296 2.2e-234 M Protein of unknown function (DUF2961)
EECMNDAG_00297 7.7e-151 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EECMNDAG_00298 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
EECMNDAG_00299 4.3e-236 malE G Bacterial extracellular solute-binding protein
EECMNDAG_00300 7.9e-247 malF G Binding-protein-dependent transport system inner membrane component
EECMNDAG_00301 1e-162 malG G Binding-protein-dependent transport system inner membrane component
EECMNDAG_00302 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_00303 5.4e-144 S HAD-hyrolase-like
EECMNDAG_00304 9.7e-141 traX S TraX protein
EECMNDAG_00305 1.3e-193 K Psort location Cytoplasmic, score
EECMNDAG_00306 0.0 M cell wall anchor domain protein
EECMNDAG_00307 4.7e-136 M LPXTG-motif cell wall anchor domain protein
EECMNDAG_00308 1.5e-184 M Cna protein B-type domain
EECMNDAG_00309 3.5e-157 srtC 3.4.22.70 M Sortase family
EECMNDAG_00310 6e-126 S membrane transporter protein
EECMNDAG_00311 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
EECMNDAG_00312 1.2e-143 S Mitochondrial biogenesis AIM24
EECMNDAG_00313 0.0 dnaK O Heat shock 70 kDa protein
EECMNDAG_00314 8e-185 L Helix-turn-helix domain
EECMNDAG_00315 2.7e-95 L Resolvase, N terminal domain
EECMNDAG_00316 2.5e-33 S Domain of unknown function (DUF4143)
EECMNDAG_00317 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
EECMNDAG_00318 4.8e-193 M Glycosyltransferase like family 2
EECMNDAG_00319 5e-148 rgpC U Transport permease protein
EECMNDAG_00320 1.8e-242 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
EECMNDAG_00321 0.0 rgpF M Rhamnan synthesis protein F
EECMNDAG_00322 4.5e-165 I Acyltransferase family
EECMNDAG_00323 2.9e-152 yfdH 2.4.2.53 GT2 M Glycosyltransferase like family 2
EECMNDAG_00324 8.7e-191 S Glucosyl transferase GtrII
EECMNDAG_00325 1.9e-147 1.1.1.339 GM NAD dependent epimerase/dehydratase family
EECMNDAG_00326 7.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EECMNDAG_00327 1e-281 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EECMNDAG_00328 2e-174 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EECMNDAG_00329 0.0 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
EECMNDAG_00330 2e-258 S AAA domain
EECMNDAG_00331 1.6e-71
EECMNDAG_00332 1.9e-09
EECMNDAG_00333 4e-301 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
EECMNDAG_00334 1.2e-56
EECMNDAG_00336 6.6e-154 EGP Major facilitator Superfamily
EECMNDAG_00337 2.9e-84 ykoE S ABC-type cobalt transport system, permease component
EECMNDAG_00338 2.1e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EECMNDAG_00339 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EECMNDAG_00340 0.0 S Tetratricopeptide repeat
EECMNDAG_00341 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EECMNDAG_00342 8.1e-307 2.8.2.22 S Arylsulfotransferase Ig-like domain
EECMNDAG_00343 5e-145 bioM P ATPases associated with a variety of cellular activities
EECMNDAG_00344 8.1e-221 E Aminotransferase class I and II
EECMNDAG_00345 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
EECMNDAG_00346 6.3e-201 S Glycosyltransferase, group 2 family protein
EECMNDAG_00347 1.4e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EECMNDAG_00348 2.4e-47 yhbY J CRS1_YhbY
EECMNDAG_00349 0.0 ecfA GP ABC transporter, ATP-binding protein
EECMNDAG_00350 3e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EECMNDAG_00351 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
EECMNDAG_00352 4.8e-113 kcsA U Ion channel
EECMNDAG_00353 9.4e-124 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EECMNDAG_00354 3.2e-276 pacS 3.6.3.54 P E1-E2 ATPase
EECMNDAG_00355 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EECMNDAG_00356 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EECMNDAG_00357 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
EECMNDAG_00358 2.9e-169
EECMNDAG_00359 0.0 O Type VII secretion system ESX-1, transport TM domain B
EECMNDAG_00360 1.3e-225 snm S WXG100 protein secretion system (Wss), protein YukD
EECMNDAG_00361 1.1e-47 esxU S Proteins of 100 residues with WXG
EECMNDAG_00362 1.5e-43 S Proteins of 100 residues with WXG
EECMNDAG_00364 3.7e-257 O Subtilase family
EECMNDAG_00365 2.7e-176
EECMNDAG_00366 1.2e-147
EECMNDAG_00367 1.1e-187
EECMNDAG_00368 1.3e-54
EECMNDAG_00369 1e-191
EECMNDAG_00370 9.6e-157 T Forkhead associated domain
EECMNDAG_00371 0.0 eccCa D FtsK/SpoIIIE family
EECMNDAG_00372 6.1e-26 XK27_00515 D Cell surface antigen C-terminus
EECMNDAG_00373 1.5e-21 XK27_00515 D Cell surface antigen C-terminus
EECMNDAG_00374 1.1e-25 XK27_00515 D Cell surface antigen C-terminus
EECMNDAG_00375 2.1e-14 XK27_00515 D Cell surface antigen C-terminus
EECMNDAG_00376 2.8e-104
EECMNDAG_00379 1e-182 cat P Cation efflux family
EECMNDAG_00380 1.9e-71 S Psort location CytoplasmicMembrane, score
EECMNDAG_00381 2.3e-75 K helix_turn_helix, Lux Regulon
EECMNDAG_00382 0.0 S Protein of unknown function DUF262
EECMNDAG_00383 9e-116 K helix_turn_helix, Lux Regulon
EECMNDAG_00384 3.2e-245 T Histidine kinase
EECMNDAG_00385 1.7e-190 V ATPases associated with a variety of cellular activities
EECMNDAG_00386 7.7e-225 V ABC-2 family transporter protein
EECMNDAG_00387 8.9e-229 V ABC-2 family transporter protein
EECMNDAG_00388 2.2e-209 rhaR1 K helix_turn_helix, arabinose operon control protein
EECMNDAG_00389 5.2e-108 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
EECMNDAG_00390 4.9e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
EECMNDAG_00391 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EECMNDAG_00392 0.0 ctpE P E1-E2 ATPase
EECMNDAG_00393 1.5e-98
EECMNDAG_00394 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EECMNDAG_00395 2.4e-133 S Protein of unknown function (DUF3159)
EECMNDAG_00396 1.7e-151 S Protein of unknown function (DUF3710)
EECMNDAG_00397 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
EECMNDAG_00398 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
EECMNDAG_00399 1.4e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
EECMNDAG_00400 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
EECMNDAG_00401 3.7e-215 E ABC transporter, substrate-binding protein, family 5
EECMNDAG_00402 9e-53 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EECMNDAG_00403 1.4e-62 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EECMNDAG_00404 2.7e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EECMNDAG_00405 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
EECMNDAG_00406 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EECMNDAG_00407 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EECMNDAG_00409 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EECMNDAG_00410 1.7e-108 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EECMNDAG_00411 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EECMNDAG_00412 3.4e-17 yccF S Inner membrane component domain
EECMNDAG_00413 5.9e-12
EECMNDAG_00414 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
EECMNDAG_00415 1e-36 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EECMNDAG_00416 2.6e-42 nadR H ATPase kinase involved in NAD metabolism
EECMNDAG_00417 2.5e-68 pnuC H Nicotinamide mononucleotide transporter
EECMNDAG_00418 1.2e-29 pnuC H Nicotinamide mononucleotide transporter
EECMNDAG_00419 7.1e-09 pnuC H Nicotinamide mononucleotide transporter
EECMNDAG_00420 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
EECMNDAG_00421 2.6e-177 S Sucrose-6F-phosphate phosphohydrolase
EECMNDAG_00422 2.4e-32 secG U Preprotein translocase SecG subunit
EECMNDAG_00423 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EECMNDAG_00424 1.3e-299 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
EECMNDAG_00425 0.0 crr G pts system, glucose-specific IIABC component
EECMNDAG_00426 2.8e-157 arbG K CAT RNA binding domain
EECMNDAG_00427 9.8e-200 I Diacylglycerol kinase catalytic domain
EECMNDAG_00428 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EECMNDAG_00430 2.1e-188 yegU O ADP-ribosylglycohydrolase
EECMNDAG_00431 1.9e-189 yegV G pfkB family carbohydrate kinase
EECMNDAG_00432 1.5e-269 U Permease for cytosine/purines, uracil, thiamine, allantoin
EECMNDAG_00433 1.5e-103 Q Isochorismatase family
EECMNDAG_00434 2.3e-214 S Choline/ethanolamine kinase
EECMNDAG_00435 5.6e-275 eat E Amino acid permease
EECMNDAG_00436 5.3e-264 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
EECMNDAG_00437 2.1e-140 yidP K UTRA
EECMNDAG_00438 5.6e-121 degU K helix_turn_helix, Lux Regulon
EECMNDAG_00439 1.7e-264 tcsS3 KT PspC domain
EECMNDAG_00440 8.3e-146 pspC KT PspC domain
EECMNDAG_00441 9.3e-93
EECMNDAG_00442 2.3e-116 S Protein of unknown function (DUF4125)
EECMNDAG_00443 0.0 S Domain of unknown function (DUF4037)
EECMNDAG_00444 3.8e-131 araJ EGP Major facilitator Superfamily
EECMNDAG_00445 1.3e-27 EGP Major facilitator Superfamily
EECMNDAG_00446 7.4e-126 S Phospholipase/Carboxylesterase
EECMNDAG_00447 1.4e-239 patB 4.4.1.8 E Aminotransferase, class I II
EECMNDAG_00448 3.9e-187 K LysR substrate binding domain protein
EECMNDAG_00449 1.8e-15
EECMNDAG_00452 1.9e-92 KL Type III restriction enzyme res subunit
EECMNDAG_00453 8.9e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
EECMNDAG_00454 9.4e-101 pdtaR T Response regulator receiver domain protein
EECMNDAG_00455 5.5e-168 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
EECMNDAG_00456 1.3e-171 whiA K May be required for sporulation
EECMNDAG_00457 1.1e-170 rapZ S Displays ATPase and GTPase activities
EECMNDAG_00458 1.2e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
EECMNDAG_00459 5.6e-214 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EECMNDAG_00460 2e-70 K COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EECMNDAG_00461 3.6e-143 T His Kinase A (phosphoacceptor) domain
EECMNDAG_00462 7e-82 S SnoaL-like domain
EECMNDAG_00463 2e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EECMNDAG_00464 7e-242 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EECMNDAG_00465 1.9e-292 E ABC transporter, substrate-binding protein, family 5
EECMNDAG_00466 4.8e-166 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_00467 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
EECMNDAG_00468 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
EECMNDAG_00469 4e-139 sapF E ATPases associated with a variety of cellular activities
EECMNDAG_00470 1.5e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
EECMNDAG_00471 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EECMNDAG_00472 0.0 macB_2 V ATPases associated with a variety of cellular activities
EECMNDAG_00473 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EECMNDAG_00474 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EECMNDAG_00475 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EECMNDAG_00476 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
EECMNDAG_00477 7.1e-286 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EECMNDAG_00478 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EECMNDAG_00479 1.2e-214 ybiR P Citrate transporter
EECMNDAG_00480 3.8e-179 rpsA J Ribosomal protein S1
EECMNDAG_00481 7.1e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EECMNDAG_00482 2.2e-172 P Zinc-uptake complex component A periplasmic
EECMNDAG_00483 2e-160 znuC P ATPases associated with a variety of cellular activities
EECMNDAG_00484 2.4e-135 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00485 3.1e-260 lacS G Psort location CytoplasmicMembrane, score 10.00
EECMNDAG_00486 5.8e-208 GK ROK family
EECMNDAG_00487 5.4e-121
EECMNDAG_00488 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
EECMNDAG_00489 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EECMNDAG_00490 1.1e-94 rpsB J Belongs to the universal ribosomal protein uS2 family
EECMNDAG_00491 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EECMNDAG_00492 1.1e-217 yxjG_1 E Psort location Cytoplasmic, score 8.87
EECMNDAG_00493 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EECMNDAG_00494 4.3e-108 J Acetyltransferase (GNAT) domain
EECMNDAG_00495 4e-76 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EECMNDAG_00496 1.3e-17 araJ EGP Major facilitator Superfamily
EECMNDAG_00497 4.7e-12 araJ EGP Major facilitator Superfamily
EECMNDAG_00499 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EECMNDAG_00500 2.1e-202 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EECMNDAG_00501 3e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EECMNDAG_00502 0.0 4.2.1.53 S MCRA family
EECMNDAG_00503 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
EECMNDAG_00504 1.1e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EECMNDAG_00505 6.2e-41
EECMNDAG_00506 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EECMNDAG_00507 1.3e-165 usp 3.5.1.28 CBM50 S CHAP domain
EECMNDAG_00508 6.5e-79 M NlpC/P60 family
EECMNDAG_00509 1.3e-190 T Universal stress protein family
EECMNDAG_00510 1.5e-73 attW O OsmC-like protein
EECMNDAG_00511 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EECMNDAG_00512 6.4e-130 folA 1.5.1.3 H dihydrofolate reductase
EECMNDAG_00513 3.6e-85 ptpA 3.1.3.48 T low molecular weight
EECMNDAG_00515 5.2e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EECMNDAG_00516 2.2e-170 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EECMNDAG_00520 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
EECMNDAG_00521 3e-162
EECMNDAG_00522 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
EECMNDAG_00523 9.3e-104 pelF GT4 M Domain of unknown function (DUF3492)
EECMNDAG_00524 3.9e-130 pelF GT4 M Domain of unknown function (DUF3492)
EECMNDAG_00525 8.1e-285 pelG S Putative exopolysaccharide Exporter (EPS-E)
EECMNDAG_00526 0.0 cotH M CotH kinase protein
EECMNDAG_00527 4.1e-158 P VTC domain
EECMNDAG_00528 2.5e-110 S Domain of unknown function (DUF4956)
EECMNDAG_00529 0.0 yliE T Putative diguanylate phosphodiesterase
EECMNDAG_00530 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
EECMNDAG_00531 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
EECMNDAG_00532 1.3e-237 S AI-2E family transporter
EECMNDAG_00533 6.3e-232 epsG M Glycosyl transferase family 21
EECMNDAG_00534 1.1e-230 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
EECMNDAG_00535 3.3e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EECMNDAG_00536 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EECMNDAG_00537 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EECMNDAG_00538 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
EECMNDAG_00539 5.8e-155 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EECMNDAG_00540 1.2e-272 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EECMNDAG_00541 3.1e-93 S Protein of unknown function (DUF3180)
EECMNDAG_00542 8.5e-165 tesB I Thioesterase-like superfamily
EECMNDAG_00543 0.0 yjjK S ATP-binding cassette protein, ChvD family
EECMNDAG_00544 5.9e-182 V Beta-lactamase
EECMNDAG_00545 4.6e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EECMNDAG_00546 2.3e-98 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
EECMNDAG_00547 7.4e-255 G ABC transporter periplasmic binding protein YcjN precursor K02027
EECMNDAG_00548 2.1e-174 U Binding-protein-dependent transport system inner membrane component
EECMNDAG_00549 4.3e-150 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_00550 0.0 G Psort location Cytoplasmic, score 8.87
EECMNDAG_00551 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EECMNDAG_00552 0.0 O Highly conserved protein containing a thioredoxin domain
EECMNDAG_00553 7.4e-235 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
EECMNDAG_00554 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
EECMNDAG_00555 8.6e-09 bdhA C Iron-containing alcohol dehydrogenase
EECMNDAG_00556 1.1e-214 bdhA C Iron-containing alcohol dehydrogenase
EECMNDAG_00557 2.1e-168 F Inosine-uridine preferring nucleoside hydrolase
EECMNDAG_00558 3.4e-291 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
EECMNDAG_00559 4.7e-227 xylR GK ROK family
EECMNDAG_00560 3.6e-61 ykoE S ABC-type cobalt transport system, permease component
EECMNDAG_00561 6.1e-38 ydcZ S Putative inner membrane exporter, YdcZ
EECMNDAG_00563 8.2e-12
EECMNDAG_00564 4.8e-41 tnp7109-21 L Integrase core domain
EECMNDAG_00565 4.1e-67 L IstB-like ATP binding protein
EECMNDAG_00566 1.4e-26 V Abi-like protein
EECMNDAG_00567 4.3e-96 S Psort location CytoplasmicMembrane, score 9.99
EECMNDAG_00568 4.9e-55 yccF S Inner membrane component domain
EECMNDAG_00569 1.5e-140 I alpha/beta hydrolase fold
EECMNDAG_00570 3.9e-31 I alpha/beta hydrolase fold
EECMNDAG_00571 2.8e-145 cobB2 K Sir2 family
EECMNDAG_00572 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
EECMNDAG_00573 9.9e-106 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
EECMNDAG_00574 8.3e-98
EECMNDAG_00575 5.6e-180 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
EECMNDAG_00576 4.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EECMNDAG_00577 7.2e-253 S UPF0210 protein
EECMNDAG_00578 4.2e-43 gcvR T Belongs to the UPF0237 family
EECMNDAG_00579 1.1e-23 lmrB EGP Major facilitator Superfamily
EECMNDAG_00580 1.5e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
EECMNDAG_00581 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
EECMNDAG_00582 3.4e-141 glpR K DeoR C terminal sensor domain
EECMNDAG_00583 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
EECMNDAG_00584 1.8e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
EECMNDAG_00585 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EECMNDAG_00586 5.2e-133 glxR K helix_turn_helix, cAMP Regulatory protein
EECMNDAG_00587 4.5e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
EECMNDAG_00588 2.9e-86 J TM2 domain
EECMNDAG_00589 8.4e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EECMNDAG_00590 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
EECMNDAG_00591 1.5e-236 S Uncharacterized conserved protein (DUF2183)
EECMNDAG_00592 2.7e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
EECMNDAG_00593 8.7e-209 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
EECMNDAG_00594 1.8e-13 lmrA1 V ABC transporter, ATP-binding protein
EECMNDAG_00595 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
EECMNDAG_00596 1.8e-182 1.1.1.65 C Aldo/keto reductase family
EECMNDAG_00597 1.9e-26 thiS 2.8.1.10 H ThiS family
EECMNDAG_00598 5.5e-127 thiF 2.7.7.73, 2.7.7.80 H ThiF family
EECMNDAG_00599 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EECMNDAG_00600 9.9e-275 cycA E Amino acid permease
EECMNDAG_00601 2.5e-89 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00602 6.1e-168 M LPXTG cell wall anchor motif
EECMNDAG_00603 0.0 inlJ M domain protein
EECMNDAG_00604 3.4e-173 3.4.22.70 M Sortase family
EECMNDAG_00605 1.3e-76 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00606 2.7e-229 P Sodium/hydrogen exchanger family
EECMNDAG_00607 0.0 V FtsX-like permease family
EECMNDAG_00608 4.1e-270 aroP E aromatic amino acid transport protein AroP K03293
EECMNDAG_00609 8.8e-12 S Protein of unknown function, DUF624
EECMNDAG_00610 1.4e-187 K helix_turn _helix lactose operon repressor
EECMNDAG_00611 4.9e-39 G beta-mannosidase
EECMNDAG_00612 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
EECMNDAG_00613 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EECMNDAG_00614 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EECMNDAG_00615 3.5e-252 yhjE EGP Sugar (and other) transporter
EECMNDAG_00616 2.6e-278 scrT G Transporter major facilitator family protein
EECMNDAG_00617 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_00618 2.2e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_00619 6.6e-224 G Bacterial extracellular solute-binding protein
EECMNDAG_00620 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
EECMNDAG_00621 1.5e-115 S Protein of unknown function, DUF624
EECMNDAG_00622 1.2e-296 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
EECMNDAG_00623 1.1e-195 K helix_turn _helix lactose operon repressor
EECMNDAG_00624 1.8e-19 E Receptor family ligand binding region
EECMNDAG_00625 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EECMNDAG_00626 3.7e-155 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EECMNDAG_00627 9.4e-297 clcA P Voltage gated chloride channel
EECMNDAG_00628 3.5e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EECMNDAG_00629 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
EECMNDAG_00630 0.0 pip S YhgE Pip domain protein
EECMNDAG_00631 0.0 pip S YhgE Pip domain protein
EECMNDAG_00632 6.3e-171 yddG EG EamA-like transporter family
EECMNDAG_00633 1.1e-186 K Helix-turn-helix XRE-family like proteins
EECMNDAG_00635 4.7e-162 htpX O Belongs to the peptidase M48B family
EECMNDAG_00636 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
EECMNDAG_00637 1.1e-186 ansA 3.5.1.1 EJ Asparaginase
EECMNDAG_00638 0.0 cadA P E1-E2 ATPase
EECMNDAG_00639 2.9e-287 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
EECMNDAG_00640 4.4e-266 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EECMNDAG_00641 1.2e-36 K helix_turn_helix, Lux Regulon
EECMNDAG_00642 2.4e-22 2.7.13.3 T Histidine kinase
EECMNDAG_00644 5.9e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EECMNDAG_00645 6.4e-174 clcA_2 P Voltage gated chloride channel
EECMNDAG_00646 4e-55
EECMNDAG_00647 4.7e-234 T GHKL domain
EECMNDAG_00648 1.1e-130 K LytTr DNA-binding domain
EECMNDAG_00649 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
EECMNDAG_00650 2e-269 KLT Domain of unknown function (DUF4032)
EECMNDAG_00651 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EECMNDAG_00652 1.1e-231 EGP Major facilitator Superfamily
EECMNDAG_00653 3.5e-13 S Psort location Extracellular, score 8.82
EECMNDAG_00655 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EECMNDAG_00656 4e-13 S Domain of unknown function (DUF4143)
EECMNDAG_00657 0.0 murJ KLT MviN-like protein
EECMNDAG_00658 4.1e-306 murJ KLT MviN-like protein
EECMNDAG_00659 0.0 M Conserved repeat domain
EECMNDAG_00660 6.3e-122 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
EECMNDAG_00661 5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
EECMNDAG_00662 2.6e-109 S LytR cell envelope-related transcriptional attenuator
EECMNDAG_00663 1.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EECMNDAG_00664 7.8e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EECMNDAG_00665 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EECMNDAG_00666 0.0 pcrA 3.6.4.12 L DNA helicase
EECMNDAG_00667 1.7e-61 S Domain of unknown function (DUF4418)
EECMNDAG_00668 5.3e-215 V FtsX-like permease family
EECMNDAG_00669 4.6e-149 lolD V ABC transporter
EECMNDAG_00670 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EECMNDAG_00671 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EECMNDAG_00672 5.6e-129 pgm3 G Phosphoglycerate mutase family
EECMNDAG_00673 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
EECMNDAG_00674 2.5e-36
EECMNDAG_00675 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EECMNDAG_00676 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EECMNDAG_00677 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EECMNDAG_00678 9.3e-57 3.4.23.43 S Type IV leader peptidase family
EECMNDAG_00679 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EECMNDAG_00680 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EECMNDAG_00681 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
EECMNDAG_00682 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
EECMNDAG_00683 3.5e-69 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EECMNDAG_00684 6.2e-40 ybdD S Selenoprotein, putative
EECMNDAG_00685 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
EECMNDAG_00686 3.2e-53 azlD E Branched-chain amino acid transport protein (AzlD)
EECMNDAG_00687 6.1e-143 azlC E AzlC protein
EECMNDAG_00688 2.1e-88 M Protein of unknown function (DUF3737)
EECMNDAG_00689 7.1e-83 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EECMNDAG_00690 6.2e-310 EGP Major Facilitator Superfamily
EECMNDAG_00691 2e-146 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
EECMNDAG_00692 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
EECMNDAG_00693 3.9e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EECMNDAG_00694 2.2e-237 patB 4.4.1.8 E Aminotransferase, class I II
EECMNDAG_00695 2e-146 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EECMNDAG_00696 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EECMNDAG_00697 0.0 lysX S Uncharacterised conserved protein (DUF2156)
EECMNDAG_00698 7.7e-242 S Putative esterase
EECMNDAG_00699 3.2e-142 ybbL V ATPases associated with a variety of cellular activities
EECMNDAG_00700 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
EECMNDAG_00701 6.8e-219 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
EECMNDAG_00703 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EECMNDAG_00704 5.2e-08
EECMNDAG_00705 2.8e-34
EECMNDAG_00706 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
EECMNDAG_00707 1.3e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
EECMNDAG_00708 4e-104
EECMNDAG_00709 0.0 typA T Elongation factor G C-terminus
EECMNDAG_00710 1.1e-248 naiP U Sugar (and other) transporter
EECMNDAG_00711 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
EECMNDAG_00712 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
EECMNDAG_00713 2e-177 xerD D recombinase XerD
EECMNDAG_00714 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EECMNDAG_00715 2.1e-25 rpmI J Ribosomal protein L35
EECMNDAG_00716 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EECMNDAG_00717 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
EECMNDAG_00718 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EECMNDAG_00719 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EECMNDAG_00720 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EECMNDAG_00721 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
EECMNDAG_00722 1.2e-36
EECMNDAG_00723 1.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
EECMNDAG_00724 4e-276 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EECMNDAG_00725 9.5e-186 V Acetyltransferase (GNAT) domain
EECMNDAG_00726 1.9e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
EECMNDAG_00727 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
EECMNDAG_00728 2e-94 3.6.1.55 F NUDIX domain
EECMNDAG_00729 0.0 P Belongs to the ABC transporter superfamily
EECMNDAG_00730 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
EECMNDAG_00731 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
EECMNDAG_00732 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
EECMNDAG_00733 1.7e-218 GK ROK family
EECMNDAG_00734 2.4e-164 2.7.1.4 G pfkB family carbohydrate kinase
EECMNDAG_00735 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
EECMNDAG_00736 1.6e-27
EECMNDAG_00737 4.2e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
EECMNDAG_00738 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
EECMNDAG_00739 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
EECMNDAG_00740 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EECMNDAG_00741 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
EECMNDAG_00742 1.1e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EECMNDAG_00743 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EECMNDAG_00744 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EECMNDAG_00745 1.4e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EECMNDAG_00746 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
EECMNDAG_00747 3.9e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EECMNDAG_00748 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EECMNDAG_00749 7e-92 mraZ K Belongs to the MraZ family
EECMNDAG_00750 0.0 L DNA helicase
EECMNDAG_00751 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EECMNDAG_00752 8.5e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EECMNDAG_00753 1e-53 M Lysin motif
EECMNDAG_00754 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EECMNDAG_00755 2.1e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EECMNDAG_00756 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
EECMNDAG_00757 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EECMNDAG_00758 1.6e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
EECMNDAG_00759 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
EECMNDAG_00760 1e-64
EECMNDAG_00761 6.4e-56 V N-Acetylmuramoyl-L-alanine amidase
EECMNDAG_00762 1.1e-33 ytrE V ATPases associated with a variety of cellular activities
EECMNDAG_00763 1.9e-220 EGP Major facilitator Superfamily
EECMNDAG_00764 1.2e-137 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EECMNDAG_00765 5.6e-219 S Domain of unknown function (DUF5067)
EECMNDAG_00766 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
EECMNDAG_00767 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
EECMNDAG_00768 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EECMNDAG_00769 1.5e-122
EECMNDAG_00770 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
EECMNDAG_00771 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EECMNDAG_00772 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EECMNDAG_00773 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
EECMNDAG_00774 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EECMNDAG_00775 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EECMNDAG_00776 4.5e-31 3.1.21.3 V DivIVA protein
EECMNDAG_00777 1.2e-40 yggT S YGGT family
EECMNDAG_00778 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EECMNDAG_00779 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EECMNDAG_00780 1.1e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EECMNDAG_00781 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
EECMNDAG_00782 1e-105 S Pilus assembly protein, PilO
EECMNDAG_00783 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
EECMNDAG_00784 3e-190 pilM NU Type IV pilus assembly protein PilM;
EECMNDAG_00785 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EECMNDAG_00786 0.0
EECMNDAG_00787 3.6e-230 pilC U Type II secretion system (T2SS), protein F
EECMNDAG_00788 1.8e-40 pilA NU Prokaryotic N-terminal methylation motif
EECMNDAG_00789 1.6e-104 S Prokaryotic N-terminal methylation motif
EECMNDAG_00790 4.9e-137 ppdC NU Prokaryotic N-terminal methylation motif
EECMNDAG_00791 0.0 pulE NU Type II/IV secretion system protein
EECMNDAG_00792 0.0 pilT NU Type II/IV secretion system protein
EECMNDAG_00793 0.0
EECMNDAG_00794 3.7e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EECMNDAG_00795 7.8e-132 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EECMNDAG_00796 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EECMNDAG_00797 3e-60 S Thiamine-binding protein
EECMNDAG_00798 1.1e-192 K helix_turn _helix lactose operon repressor
EECMNDAG_00799 2.8e-241 lacY P LacY proton/sugar symporter
EECMNDAG_00800 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
EECMNDAG_00801 3.2e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_00802 9.1e-206 P NMT1/THI5 like
EECMNDAG_00803 2.7e-217 iunH1 3.2.2.1 F nucleoside hydrolase
EECMNDAG_00804 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EECMNDAG_00805 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
EECMNDAG_00806 0.0 I acetylesterase activity
EECMNDAG_00807 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EECMNDAG_00808 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EECMNDAG_00809 4.4e-238 2.7.11.1 NU Tfp pilus assembly protein FimV
EECMNDAG_00811 6.5e-75 S Protein of unknown function (DUF3052)
EECMNDAG_00812 2.2e-154 lon T Belongs to the peptidase S16 family
EECMNDAG_00813 2.8e-285 S Zincin-like metallopeptidase
EECMNDAG_00814 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
EECMNDAG_00815 4.7e-269 mphA S Aminoglycoside phosphotransferase
EECMNDAG_00816 3.6e-32 S Protein of unknown function (DUF3107)
EECMNDAG_00817 4.5e-174 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
EECMNDAG_00818 2.1e-117 S Vitamin K epoxide reductase
EECMNDAG_00819 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
EECMNDAG_00820 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EECMNDAG_00821 1.2e-13 S lipid catabolic process
EECMNDAG_00822 5e-301 E ABC transporter, substrate-binding protein, family 5
EECMNDAG_00823 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
EECMNDAG_00824 3.5e-51 S Patatin-like phospholipase
EECMNDAG_00825 1.5e-289 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
EECMNDAG_00826 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EECMNDAG_00827 2.1e-213 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EECMNDAG_00828 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EECMNDAG_00829 8.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EECMNDAG_00830 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EECMNDAG_00831 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
EECMNDAG_00832 2.1e-51 S Protein of unknown function (DUF2469)
EECMNDAG_00833 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
EECMNDAG_00834 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EECMNDAG_00835 1.1e-78 K helix_turn_helix ASNC type
EECMNDAG_00836 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
EECMNDAG_00837 0.0 S domain protein
EECMNDAG_00838 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EECMNDAG_00839 1.9e-289 E Bacterial extracellular solute-binding proteins, family 5 Middle
EECMNDAG_00840 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EECMNDAG_00841 4.9e-134 KT Transcriptional regulatory protein, C terminal
EECMNDAG_00842 4.9e-134
EECMNDAG_00843 9.4e-98 mntP P Probably functions as a manganese efflux pump
EECMNDAG_00844 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EECMNDAG_00845 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
EECMNDAG_00846 7.1e-175 M LPXTG-motif cell wall anchor domain protein
EECMNDAG_00847 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
EECMNDAG_00848 3.3e-192 yfdV S Membrane transport protein
EECMNDAG_00849 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
EECMNDAG_00851 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EECMNDAG_00852 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
EECMNDAG_00853 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EECMNDAG_00854 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EECMNDAG_00855 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EECMNDAG_00856 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EECMNDAG_00857 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EECMNDAG_00858 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EECMNDAG_00859 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EECMNDAG_00860 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EECMNDAG_00861 1.2e-148 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
EECMNDAG_00862 1.8e-194
EECMNDAG_00863 2.7e-180
EECMNDAG_00864 8.4e-171 trxA2 O Tetratricopeptide repeat
EECMNDAG_00865 4.7e-122 cyaA 4.6.1.1 S CYTH
EECMNDAG_00867 8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
EECMNDAG_00868 4.8e-271 mmuP E amino acid
EECMNDAG_00869 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EECMNDAG_00870 1e-298 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EECMNDAG_00871 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
EECMNDAG_00872 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EECMNDAG_00873 2e-285 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
EECMNDAG_00874 2.1e-210 K helix_turn _helix lactose operon repressor
EECMNDAG_00875 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
EECMNDAG_00876 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
EECMNDAG_00877 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EECMNDAG_00878 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EECMNDAG_00879 1.1e-161 cydD V ABC transporter transmembrane region
EECMNDAG_00880 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EECMNDAG_00881 3.2e-101
EECMNDAG_00882 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EECMNDAG_00883 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EECMNDAG_00884 2.1e-285 thrC 4.2.3.1 E Threonine synthase N terminus
EECMNDAG_00885 4.6e-233 EGP Major facilitator Superfamily
EECMNDAG_00886 1e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
EECMNDAG_00887 4.3e-174 G Fic/DOC family
EECMNDAG_00888 7.7e-145
EECMNDAG_00889 9.1e-164 IQ Enoyl-(Acyl carrier protein) reductase
EECMNDAG_00890 1.4e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EECMNDAG_00891 2.3e-57 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EECMNDAG_00892 1.1e-95 bcp 1.11.1.15 O Redoxin
EECMNDAG_00893 1.9e-25 S Psort location Cytoplasmic, score 8.87
EECMNDAG_00894 7.4e-95 S Pyridoxamine 5'-phosphate oxidase
EECMNDAG_00895 0.0 S Histidine phosphatase superfamily (branch 2)
EECMNDAG_00896 6e-44 L transposition
EECMNDAG_00897 1.1e-23 C Acetamidase/Formamidase family
EECMNDAG_00898 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
EECMNDAG_00899 9.2e-175 V ATPases associated with a variety of cellular activities
EECMNDAG_00900 2.8e-123 S ABC-2 family transporter protein
EECMNDAG_00901 4.4e-123 S Haloacid dehalogenase-like hydrolase
EECMNDAG_00902 1.7e-63 recN L May be involved in recombinational repair of damaged DNA
EECMNDAG_00903 0.0 M probably involved in cell wall
EECMNDAG_00904 8.5e-251 3.2.1.14 GH18 S Carbohydrate binding domain
EECMNDAG_00905 0.0 T Diguanylate cyclase, GGDEF domain
EECMNDAG_00906 3.2e-189 lacR K Transcriptional regulator, LacI family
EECMNDAG_00907 2.1e-244 nagA 3.5.1.25 G Amidohydrolase family
EECMNDAG_00908 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EECMNDAG_00909 0.0 G Glycosyl hydrolase family 20, domain 2
EECMNDAG_00910 3e-173 2.7.1.2 GK ROK family
EECMNDAG_00911 4.4e-164 G ABC transporter permease
EECMNDAG_00912 7.5e-147 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_00913 4.2e-242 G Bacterial extracellular solute-binding protein
EECMNDAG_00915 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
EECMNDAG_00916 3.9e-187 K helix_turn _helix lactose operon repressor
EECMNDAG_00917 2.1e-260 G Bacterial extracellular solute-binding protein
EECMNDAG_00918 6e-118 cbiQ P Cobalt transport protein
EECMNDAG_00919 3.6e-252 argE E Peptidase dimerisation domain
EECMNDAG_00920 3.6e-93 S Protein of unknown function (DUF3043)
EECMNDAG_00921 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EECMNDAG_00922 6e-143 S Domain of unknown function (DUF4191)
EECMNDAG_00923 7.8e-282 glnA 6.3.1.2 E glutamine synthetase
EECMNDAG_00924 4e-42 V DNA modification
EECMNDAG_00925 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
EECMNDAG_00926 1.5e-17 L HNH endonuclease
EECMNDAG_00928 2.9e-17
EECMNDAG_00929 2.7e-94 yvdD 3.2.2.10 S Possible lysine decarboxylase
EECMNDAG_00931 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EECMNDAG_00932 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
EECMNDAG_00933 3.2e-98
EECMNDAG_00934 4.1e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EECMNDAG_00935 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EECMNDAG_00936 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EECMNDAG_00937 5.4e-242 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
EECMNDAG_00938 4.3e-80 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EECMNDAG_00939 2.3e-108 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EECMNDAG_00940 0.0 lmrA2 V ABC transporter transmembrane region
EECMNDAG_00941 1.7e-132 lmrA1 V ABC transporter, ATP-binding protein
EECMNDAG_00942 1.3e-113 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EECMNDAG_00943 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EECMNDAG_00944 3.9e-91
EECMNDAG_00945 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
EECMNDAG_00946 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EECMNDAG_00948 5.5e-141 cpaE D bacterial-type flagellum organization
EECMNDAG_00949 2.7e-185 cpaF U Type II IV secretion system protein
EECMNDAG_00950 1.2e-132 U Type ii secretion system
EECMNDAG_00951 6.1e-91 gspF NU Type II secretion system (T2SS), protein F
EECMNDAG_00952 1.3e-42 S Protein of unknown function (DUF4244)
EECMNDAG_00953 5.1e-60 U TadE-like protein
EECMNDAG_00954 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
EECMNDAG_00955 4.9e-218 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
EECMNDAG_00956 3.5e-193 S Psort location CytoplasmicMembrane, score
EECMNDAG_00957 1.1e-96 K Bacterial regulatory proteins, tetR family
EECMNDAG_00958 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
EECMNDAG_00959 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EECMNDAG_00960 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EECMNDAG_00961 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
EECMNDAG_00962 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EECMNDAG_00963 1.7e-30 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EECMNDAG_00964 4.5e-31
EECMNDAG_00965 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
EECMNDAG_00966 2.8e-165 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EECMNDAG_00967 9.9e-80 S Protein of unknown function (DUF3000)
EECMNDAG_00968 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
EECMNDAG_00969 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EECMNDAG_00970 1.2e-129 yebE S DUF218 domain
EECMNDAG_00971 4.9e-128 E Psort location Cytoplasmic, score 8.87
EECMNDAG_00972 3e-159 O Thioredoxin
EECMNDAG_00973 1.2e-158 msbA2 3.6.3.44 V ABC transporter transmembrane region
EECMNDAG_00974 4.2e-138 3.6.3.44 V ABC transporter
EECMNDAG_00975 0.0 KLT Lanthionine synthetase C-like protein
EECMNDAG_00976 3.2e-121 K helix_turn_helix, Lux Regulon
EECMNDAG_00977 4.8e-136 2.7.13.3 T Histidine kinase
EECMNDAG_00980 1.3e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EECMNDAG_00981 7.8e-148 S phosphoesterase or phosphohydrolase
EECMNDAG_00982 2.8e-210
EECMNDAG_00983 7.2e-152 T LytTr DNA-binding domain
EECMNDAG_00984 3e-251 T GHKL domain
EECMNDAG_00985 1.5e-163 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EECMNDAG_00986 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EECMNDAG_00987 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EECMNDAG_00988 1.1e-251 corC S CBS domain
EECMNDAG_00989 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EECMNDAG_00990 5.9e-208 phoH T PhoH-like protein
EECMNDAG_00991 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
EECMNDAG_00992 3.8e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EECMNDAG_00994 3e-162 spoU 2.1.1.185 J SpoU rRNA Methylase family
EECMNDAG_00995 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EECMNDAG_00996 2.7e-108 yitW S Iron-sulfur cluster assembly protein
EECMNDAG_00997 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
EECMNDAG_00998 1.9e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EECMNDAG_00999 1e-142 sufC O FeS assembly ATPase SufC
EECMNDAG_01000 6.1e-235 sufD O FeS assembly protein SufD
EECMNDAG_01001 1.6e-290 sufB O FeS assembly protein SufB
EECMNDAG_01002 0.0 S L,D-transpeptidase catalytic domain
EECMNDAG_01003 1.1e-200 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EECMNDAG_01004 9.8e-42 M domain protein
EECMNDAG_01005 1.3e-205 M domain protein
EECMNDAG_01006 9.2e-71 pdxH S Pfam:Pyridox_oxidase
EECMNDAG_01007 4.5e-233 XK27_00240 K Fic/DOC family
EECMNDAG_01009 3.3e-118
EECMNDAG_01010 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EECMNDAG_01011 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EECMNDAG_01012 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EECMNDAG_01013 2.6e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EECMNDAG_01014 1.8e-107 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
EECMNDAG_01015 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
EECMNDAG_01016 1.5e-230 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
EECMNDAG_01017 1.1e-268 G ABC transporter substrate-binding protein
EECMNDAG_01018 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
EECMNDAG_01019 3.3e-96 M Peptidase family M23
EECMNDAG_01020 4.3e-63
EECMNDAG_01023 5e-125 XK27_06785 V ABC transporter
EECMNDAG_01024 1.9e-33 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EECMNDAG_01025 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EECMNDAG_01026 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
EECMNDAG_01027 2.7e-123 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EECMNDAG_01028 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EECMNDAG_01029 3.5e-154 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
EECMNDAG_01030 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
EECMNDAG_01031 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EECMNDAG_01032 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
EECMNDAG_01033 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EECMNDAG_01034 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
EECMNDAG_01035 4e-19
EECMNDAG_01036 6.4e-184 gguB U Branched-chain amino acid transport system / permease component
EECMNDAG_01037 3e-271 araG 3.6.3.17 G ATPases associated with a variety of cellular activities
EECMNDAG_01038 2.3e-186 G Periplasmic binding protein domain
EECMNDAG_01039 5e-178 GK ROK family
EECMNDAG_01040 7.1e-126 xylG 3.6.3.17 G ATPases associated with a variety of cellular activities
EECMNDAG_01041 5.4e-253 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EECMNDAG_01042 4.5e-71 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
EECMNDAG_01047 1.2e-129 topB 5.99.1.2 L DNA topoisomerase
EECMNDAG_01049 2.5e-76 XK27_08505 D nucleotidyltransferase activity
EECMNDAG_01050 2.3e-75 parB K Belongs to the ParB family
EECMNDAG_01051 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
EECMNDAG_01052 1.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EECMNDAG_01053 8e-91 jag S Putative single-stranded nucleic acids-binding domain
EECMNDAG_01054 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
EECMNDAG_01055 1.5e-43 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EECMNDAG_01056 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EECMNDAG_01057 2.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EECMNDAG_01058 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EECMNDAG_01059 6.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EECMNDAG_01060 6.2e-90 S Protein of unknown function (DUF721)
EECMNDAG_01061 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EECMNDAG_01062 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EECMNDAG_01063 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
EECMNDAG_01064 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EECMNDAG_01065 1.4e-57 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EECMNDAG_01069 3.1e-101 S Protein of unknown function DUF45
EECMNDAG_01070 1e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EECMNDAG_01071 2.8e-241 ytfL P Transporter associated domain
EECMNDAG_01072 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EECMNDAG_01073 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EECMNDAG_01074 0.0 yjjP S Threonine/Serine exporter, ThrE
EECMNDAG_01075 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EECMNDAG_01076 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EECMNDAG_01077 8.1e-37 S Protein of unknown function (DUF3073)
EECMNDAG_01078 1.7e-63 I Sterol carrier protein
EECMNDAG_01079 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EECMNDAG_01080 3.4e-35
EECMNDAG_01081 1.4e-147 gluP 3.4.21.105 S Rhomboid family
EECMNDAG_01082 7.3e-240 L ribosomal rna small subunit methyltransferase
EECMNDAG_01083 3.1e-57 crgA D Involved in cell division
EECMNDAG_01084 6.8e-142 S Bacterial protein of unknown function (DUF881)
EECMNDAG_01085 8.7e-209 srtA 3.4.22.70 M Sortase family
EECMNDAG_01086 1.1e-115 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
EECMNDAG_01087 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
EECMNDAG_01088 5.8e-177 T Protein tyrosine kinase
EECMNDAG_01089 5.2e-265 pbpA M penicillin-binding protein
EECMNDAG_01090 1.7e-261 rodA D Belongs to the SEDS family
EECMNDAG_01091 3.4e-241 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
EECMNDAG_01092 1.1e-71 fhaB T Inner membrane component of T3SS, cytoplasmic domain
EECMNDAG_01093 1.2e-131 fhaA T Protein of unknown function (DUF2662)
EECMNDAG_01094 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
EECMNDAG_01095 6e-225 2.7.13.3 T Histidine kinase
EECMNDAG_01096 3.2e-113 K helix_turn_helix, Lux Regulon
EECMNDAG_01097 6.6e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
EECMNDAG_01098 8.8e-160 yicL EG EamA-like transporter family
EECMNDAG_01099 3.2e-86 XK27_10430 S NAD(P)H-binding
EECMNDAG_01100 7.8e-44 ydeP K HxlR-like helix-turn-helix
EECMNDAG_01103 4.9e-34 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EECMNDAG_01105 2.7e-41 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EECMNDAG_01106 5.6e-12 KL SNF2 family N-terminal domain
EECMNDAG_01107 3.4e-55 DJ Addiction module toxin, RelE StbE family
EECMNDAG_01108 1.3e-48 S Antitoxin component of a toxin-antitoxin (TA) module
EECMNDAG_01109 1.7e-125 S Short repeat of unknown function (DUF308)
EECMNDAG_01110 3.5e-168 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_01111 6e-73 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
EECMNDAG_01112 1e-105 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
EECMNDAG_01113 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
EECMNDAG_01114 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EECMNDAG_01115 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01116 3.4e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
EECMNDAG_01117 2.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
EECMNDAG_01118 7.2e-189 K Bacterial regulatory proteins, lacI family
EECMNDAG_01119 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
EECMNDAG_01120 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EECMNDAG_01121 4.5e-249 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
EECMNDAG_01122 1.3e-279 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EECMNDAG_01123 2.9e-106 S Membrane
EECMNDAG_01124 2.3e-48 ydcZ S Putative inner membrane exporter, YdcZ
EECMNDAG_01125 6.3e-44
EECMNDAG_01126 4.7e-07
EECMNDAG_01127 1.5e-244 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EECMNDAG_01128 8.4e-54 M cell wall binding repeat
EECMNDAG_01129 6e-38 nrdH O Glutaredoxin
EECMNDAG_01130 1.6e-225 S Putative ABC-transporter type IV
EECMNDAG_01131 0.0 pip S YhgE Pip domain protein
EECMNDAG_01132 2.4e-274 pip S YhgE Pip domain protein
EECMNDAG_01133 6.1e-88 K Psort location Cytoplasmic, score 8.87
EECMNDAG_01134 8.2e-62 S FMN_bind
EECMNDAG_01135 9e-150 macB V ABC transporter, ATP-binding protein
EECMNDAG_01136 1e-200 Z012_06715 V FtsX-like permease family
EECMNDAG_01138 8e-220 macB_2 V ABC transporter permease
EECMNDAG_01139 4.2e-231 S Predicted membrane protein (DUF2318)
EECMNDAG_01140 4.1e-92 tpd P Fe2+ transport protein
EECMNDAG_01141 1e-199 efeU_1 P Iron permease FTR1 family
EECMNDAG_01142 2.9e-176 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EECMNDAG_01143 2.1e-266 trkB P Cation transport protein
EECMNDAG_01144 3e-116 trkA P TrkA-N domain
EECMNDAG_01145 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EECMNDAG_01146 3.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EECMNDAG_01147 5.6e-149 L Tetratricopeptide repeat
EECMNDAG_01148 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EECMNDAG_01149 0.0 S Protein of unknown function (DUF975)
EECMNDAG_01150 8.6e-137 S Putative ABC-transporter type IV
EECMNDAG_01151 3.7e-93 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EECMNDAG_01152 2.9e-279 argH 4.3.2.1 E argininosuccinate lyase
EECMNDAG_01153 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EECMNDAG_01154 2.3e-82 argR K Regulates arginine biosynthesis genes
EECMNDAG_01155 2.8e-57 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EECMNDAG_01156 6.2e-72 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EECMNDAG_01158 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
EECMNDAG_01159 5.7e-172 corA P CorA-like Mg2+ transporter protein
EECMNDAG_01160 1.6e-44 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EECMNDAG_01161 2.1e-263 EGP Major facilitator Superfamily
EECMNDAG_01162 2.2e-96 S GtrA-like protein
EECMNDAG_01163 2.3e-62 S Macrophage migration inhibitory factor (MIF)
EECMNDAG_01164 1.8e-31 ydcZ S Putative inner membrane exporter, YdcZ
EECMNDAG_01166 0.0 tetP J Elongation factor G, domain IV
EECMNDAG_01170 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_01171 1.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
EECMNDAG_01172 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
EECMNDAG_01173 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EECMNDAG_01174 7.3e-106
EECMNDAG_01175 3.5e-178 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EECMNDAG_01176 8.7e-19 3.2.1.78 GH26 G Glycosyl hydrolase family 26
EECMNDAG_01177 4.2e-124 dedA S SNARE associated Golgi protein
EECMNDAG_01179 3.3e-129 S HAD hydrolase, family IA, variant 3
EECMNDAG_01180 8.6e-47
EECMNDAG_01181 4.5e-115 hspR K transcriptional regulator, MerR family
EECMNDAG_01182 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
EECMNDAG_01183 5.3e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EECMNDAG_01184 1.2e-73 yceD S Uncharacterized ACR, COG1399
EECMNDAG_01185 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EECMNDAG_01186 1.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EECMNDAG_01187 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
EECMNDAG_01188 5.7e-92 ilvN 2.2.1.6 E ACT domain
EECMNDAG_01189 2.6e-89
EECMNDAG_01190 0.0 yjjK S ABC transporter
EECMNDAG_01191 1.6e-151 guaA1 6.3.5.2 F Peptidase C26
EECMNDAG_01192 9.3e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
EECMNDAG_01193 1.6e-94
EECMNDAG_01195 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EECMNDAG_01196 5.8e-178 S Endonuclease/Exonuclease/phosphatase family
EECMNDAG_01197 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EECMNDAG_01198 1.8e-34 CP_0960 S Belongs to the UPF0109 family
EECMNDAG_01199 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EECMNDAG_01200 2.6e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EECMNDAG_01201 6.5e-105 rsmD 2.1.1.171 L Conserved hypothetical protein 95
EECMNDAG_01202 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
EECMNDAG_01203 8.4e-30 rpmB J Ribosomal L28 family
EECMNDAG_01204 0.0 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01205 2.1e-228 yxiO S Vacuole effluxer Atg22 like
EECMNDAG_01206 1.9e-127 gntR K FCD
EECMNDAG_01207 6.2e-83 gntK 2.7.1.12 F Shikimate kinase
EECMNDAG_01208 6e-228 gnuT EG GntP family permease
EECMNDAG_01210 2e-166 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
EECMNDAG_01211 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
EECMNDAG_01212 6.3e-125 K Bacterial regulatory proteins, tetR family
EECMNDAG_01213 1.6e-227 MA20_36090 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01214 3.8e-229 MA20_36090 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01215 1.7e-137 M Mechanosensitive ion channel
EECMNDAG_01216 7.4e-179 S CAAX protease self-immunity
EECMNDAG_01217 2.6e-214 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EECMNDAG_01218 2.8e-141 U Binding-protein-dependent transport system inner membrane component
EECMNDAG_01219 1.5e-156 U Binding-protein-dependent transport system inner membrane component
EECMNDAG_01220 5.8e-219 P Bacterial extracellular solute-binding protein
EECMNDAG_01221 9.8e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EECMNDAG_01222 5e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
EECMNDAG_01223 5.5e-177 plsC2 2.3.1.51 I Phosphate acyltransferases
EECMNDAG_01224 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EECMNDAG_01225 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
EECMNDAG_01226 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EECMNDAG_01227 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EECMNDAG_01228 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
EECMNDAG_01229 3e-268 S Calcineurin-like phosphoesterase
EECMNDAG_01232 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EECMNDAG_01233 9.6e-16 yceD S Uncharacterized ACR, COG1399
EECMNDAG_01234 8.5e-134
EECMNDAG_01235 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EECMNDAG_01236 7.2e-58 S Protein of unknown function (DUF3039)
EECMNDAG_01237 1.7e-195 yghZ C Aldo/keto reductase family
EECMNDAG_01238 3.2e-77 soxR K MerR, DNA binding
EECMNDAG_01239 1.2e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EECMNDAG_01240 1.9e-138 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EECMNDAG_01241 1.1e-250 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EECMNDAG_01242 1.7e-243 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
EECMNDAG_01243 1.8e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
EECMNDAG_01246 1.3e-179 S Auxin Efflux Carrier
EECMNDAG_01247 0.0 pgi 5.3.1.9 G Belongs to the GPI family
EECMNDAG_01248 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EECMNDAG_01249 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EECMNDAG_01250 7.2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EECMNDAG_01251 5e-128 V ATPases associated with a variety of cellular activities
EECMNDAG_01252 4.6e-269 V Efflux ABC transporter, permease protein
EECMNDAG_01253 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
EECMNDAG_01254 2e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
EECMNDAG_01255 1.9e-308 rne 3.1.26.12 J Ribonuclease E/G family
EECMNDAG_01256 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EECMNDAG_01257 2.6e-39 rpmA J Ribosomal L27 protein
EECMNDAG_01258 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EECMNDAG_01259 5.1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EECMNDAG_01260 3.3e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
EECMNDAG_01262 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EECMNDAG_01263 4.2e-128 nusG K Participates in transcription elongation, termination and antitermination
EECMNDAG_01264 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EECMNDAG_01265 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EECMNDAG_01266 5.9e-143 QT PucR C-terminal helix-turn-helix domain
EECMNDAG_01267 0.0
EECMNDAG_01268 1.7e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
EECMNDAG_01269 2.1e-79 bioY S BioY family
EECMNDAG_01270 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
EECMNDAG_01271 0.0 pccB I Carboxyl transferase domain
EECMNDAG_01272 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
EECMNDAG_01273 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EECMNDAG_01274 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
EECMNDAG_01276 5.4e-116
EECMNDAG_01277 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EECMNDAG_01278 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EECMNDAG_01279 5.8e-149 P Cobalt transport protein
EECMNDAG_01280 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
EECMNDAG_01281 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
EECMNDAG_01282 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
EECMNDAG_01283 1.1e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EECMNDAG_01284 3.1e-83 yraN L Belongs to the UPF0102 family
EECMNDAG_01285 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
EECMNDAG_01286 5.5e-253 dprA 5.99.1.2 LU DNA recombination-mediator protein A
EECMNDAG_01287 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
EECMNDAG_01288 2e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
EECMNDAG_01289 4.8e-117 safC S O-methyltransferase
EECMNDAG_01290 3.6e-244 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EECMNDAG_01291 2.8e-09 S Protein of unknown function (DUF805)
EECMNDAG_01292 7e-184
EECMNDAG_01293 3.4e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
EECMNDAG_01294 3.8e-196 GT4 M Psort location Cytoplasmic, score 8.87
EECMNDAG_01295 5.7e-244 MA20_17390 GT4 M Glycosyl transferases group 1
EECMNDAG_01296 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
EECMNDAG_01297 6.5e-148 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01298 1.7e-162 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01299 3e-270 G Bacterial extracellular solute-binding protein
EECMNDAG_01300 3.1e-184 K Psort location Cytoplasmic, score
EECMNDAG_01301 2.4e-181 K helix_turn _helix lactose operon repressor
EECMNDAG_01302 1.8e-223 G Bacterial extracellular solute-binding protein
EECMNDAG_01303 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
EECMNDAG_01304 2.5e-144 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01305 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
EECMNDAG_01306 0.0 3.2.1.22 G lipolytic protein G-D-S-L family
EECMNDAG_01307 7.1e-271 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
EECMNDAG_01308 4.1e-232 G Bacterial extracellular solute-binding protein
EECMNDAG_01309 5.7e-156 malC G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01310 7.4e-142 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01311 5.4e-160 K Periplasmic binding protein domain
EECMNDAG_01312 5.9e-46 K Acetyltransferase (GNAT) family
EECMNDAG_01313 1.3e-23 S Protein of unknown function (DUF1778)
EECMNDAG_01314 1.1e-06 2.7.13.3 T Histidine kinase
EECMNDAG_01315 1e-45 K helix_turn_helix, Lux Regulon
EECMNDAG_01316 3.8e-40
EECMNDAG_01317 2.4e-115
EECMNDAG_01318 4.9e-301 S Calcineurin-like phosphoesterase
EECMNDAG_01319 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EECMNDAG_01320 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
EECMNDAG_01321 2.1e-256 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
EECMNDAG_01322 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
EECMNDAG_01323 1.1e-195 K helix_turn _helix lactose operon repressor
EECMNDAG_01324 1.3e-203 abf G Glycosyl hydrolases family 43
EECMNDAG_01325 1.1e-292 G Bacterial extracellular solute-binding protein
EECMNDAG_01326 4.6e-169 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01327 1.7e-163 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01328 2.1e-183 G beta-fructofuranosidase activity
EECMNDAG_01329 8.5e-101 S Protein of unknown function, DUF624
EECMNDAG_01330 2.6e-25 S Beta-L-arabinofuranosidase, GH127
EECMNDAG_01331 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EECMNDAG_01332 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
EECMNDAG_01333 2.4e-236 glf 5.4.99.9 M UDP-galactopyranose mutase
EECMNDAG_01334 1.9e-190 3.6.1.27 I PAP2 superfamily
EECMNDAG_01335 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EECMNDAG_01336 1.8e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EECMNDAG_01337 1.9e-193 holB 2.7.7.7 L DNA polymerase III
EECMNDAG_01338 2.1e-183 K helix_turn _helix lactose operon repressor
EECMNDAG_01339 6e-39 ptsH G PTS HPr component phosphorylation site
EECMNDAG_01340 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EECMNDAG_01341 1.1e-106 S Phosphatidylethanolamine-binding protein
EECMNDAG_01342 0.0 pepD E Peptidase family C69
EECMNDAG_01343 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
EECMNDAG_01344 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EECMNDAG_01345 6.7e-72 K MerR family regulatory protein
EECMNDAG_01346 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
EECMNDAG_01347 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EECMNDAG_01348 4.6e-119 yoaP E YoaP-like
EECMNDAG_01350 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EECMNDAG_01351 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
EECMNDAG_01352 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
EECMNDAG_01353 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
EECMNDAG_01354 7.1e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
EECMNDAG_01355 0.0 comE S Competence protein
EECMNDAG_01356 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
EECMNDAG_01357 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EECMNDAG_01358 3.5e-42 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EECMNDAG_01359 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EECMNDAG_01360 1.5e-138 S SdpI/YhfL protein family
EECMNDAG_01361 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
EECMNDAG_01368 9e-184 lacR K Transcriptional regulator, LacI family
EECMNDAG_01369 6.3e-79 lacS G Psort location CytoplasmicMembrane, score 10.00
EECMNDAG_01370 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
EECMNDAG_01371 4.9e-120 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
EECMNDAG_01372 5.3e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
EECMNDAG_01373 1.1e-113 vex2 V ABC transporter, ATP-binding protein
EECMNDAG_01374 1e-213 vex1 V Efflux ABC transporter, permease protein
EECMNDAG_01375 2.9e-241 vex3 V ABC transporter permease
EECMNDAG_01376 6.7e-27 lacS G Psort location CytoplasmicMembrane, score 10.00
EECMNDAG_01377 9.7e-43 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EECMNDAG_01378 7.5e-228 yhjX EGP Major facilitator Superfamily
EECMNDAG_01379 0.0 trxB1 1.8.1.9 C Thioredoxin domain
EECMNDAG_01380 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
EECMNDAG_01381 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EECMNDAG_01382 8.9e-198 K helix_turn _helix lactose operon repressor
EECMNDAG_01383 6.2e-241 mntH P H( )-stimulated, divalent metal cation uptake system
EECMNDAG_01384 1.4e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
EECMNDAG_01385 6.2e-127 L Protein of unknown function (DUF1524)
EECMNDAG_01386 5.4e-242 T Diguanylate cyclase (GGDEF) domain protein
EECMNDAG_01387 1.4e-281 EGP Major facilitator Superfamily
EECMNDAG_01388 1.6e-46
EECMNDAG_01389 1.1e-186 S Endonuclease/Exonuclease/phosphatase family
EECMNDAG_01390 2.2e-291 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
EECMNDAG_01391 8.3e-31 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01392 6.9e-187 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01393 2e-13
EECMNDAG_01395 1.5e-44
EECMNDAG_01396 2.5e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
EECMNDAG_01397 1.9e-62 S Protein of unknown function (DUF4235)
EECMNDAG_01398 2.9e-136 G Phosphoglycerate mutase family
EECMNDAG_01399 6.6e-259 amyE G Bacterial extracellular solute-binding protein
EECMNDAG_01400 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
EECMNDAG_01401 1.4e-264 amyE G Bacterial extracellular solute-binding protein
EECMNDAG_01402 5.9e-186 K Periplasmic binding protein-like domain
EECMNDAG_01403 1.7e-182 K Psort location Cytoplasmic, score
EECMNDAG_01404 3.7e-154 msmF G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01405 4e-153 rafG G ABC transporter permease
EECMNDAG_01406 2.6e-106 S Protein of unknown function, DUF624
EECMNDAG_01407 6.6e-47 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EECMNDAG_01408 1.5e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EECMNDAG_01409 1.7e-130 cas4 3.1.12.1 L Domain of unknown function DUF83
EECMNDAG_01410 4.5e-152 csd2 L CRISPR-associated protein Cas7
EECMNDAG_01411 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
EECMNDAG_01412 1.2e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
EECMNDAG_01413 0.0 cas3 L DEAD-like helicases superfamily
EECMNDAG_01414 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EECMNDAG_01415 8.9e-105 lacS G Psort location CytoplasmicMembrane, score 10.00
EECMNDAG_01416 8.8e-48 S Psort location Cytoplasmic, score
EECMNDAG_01417 2.6e-138
EECMNDAG_01418 1e-179 3.4.22.70 M Sortase family
EECMNDAG_01419 6e-275 M LPXTG-motif cell wall anchor domain protein
EECMNDAG_01420 0.0 S LPXTG-motif cell wall anchor domain protein
EECMNDAG_01421 3.7e-10 S LPXTG-motif cell wall anchor domain protein
EECMNDAG_01422 3.6e-13 S GtrA-like protein
EECMNDAG_01423 5.2e-189 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EECMNDAG_01424 2.9e-13 S Transposon-encoded protein TnpV
EECMNDAG_01425 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
EECMNDAG_01426 3.7e-164 S LPXTG-motif cell wall anchor domain protein
EECMNDAG_01427 8.6e-246 dinF V MatE
EECMNDAG_01428 3.5e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EECMNDAG_01429 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EECMNDAG_01430 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EECMNDAG_01431 1e-47 S Domain of unknown function (DUF4193)
EECMNDAG_01432 3.5e-146 S Protein of unknown function (DUF3071)
EECMNDAG_01433 1e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
EECMNDAG_01434 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EECMNDAG_01435 0.0 lhr L DEAD DEAH box helicase
EECMNDAG_01436 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
EECMNDAG_01437 2.4e-79 S Protein of unknown function (DUF2975)
EECMNDAG_01438 5.6e-242 T PhoQ Sensor
EECMNDAG_01439 1.5e-222 G Major Facilitator Superfamily
EECMNDAG_01440 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EECMNDAG_01441 3.4e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EECMNDAG_01442 4.3e-118
EECMNDAG_01443 9.1e-198 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
EECMNDAG_01444 0.0 pknL 2.7.11.1 KLT PASTA
EECMNDAG_01445 9.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
EECMNDAG_01446 1.3e-97
EECMNDAG_01447 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EECMNDAG_01448 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EECMNDAG_01449 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EECMNDAG_01450 1.3e-122 recX S Modulates RecA activity
EECMNDAG_01451 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EECMNDAG_01452 3e-46 S Protein of unknown function (DUF3046)
EECMNDAG_01453 1.6e-80 K Helix-turn-helix XRE-family like proteins
EECMNDAG_01454 6.1e-97 cinA 3.5.1.42 S Belongs to the CinA family
EECMNDAG_01455 4.1e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EECMNDAG_01456 0.0 ftsK D FtsK SpoIIIE family protein
EECMNDAG_01457 1.4e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EECMNDAG_01458 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EECMNDAG_01459 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
EECMNDAG_01460 8e-177 ydeD EG EamA-like transporter family
EECMNDAG_01461 1.4e-124 ybhL S Belongs to the BI1 family
EECMNDAG_01462 6.7e-60 S Domain of unknown function (DUF5067)
EECMNDAG_01463 5.1e-243 T Histidine kinase
EECMNDAG_01464 3e-235 G MFS/sugar transport protein
EECMNDAG_01465 3.2e-286 S LPXTG-motif cell wall anchor domain protein
EECMNDAG_01467 1.3e-65 L Helix-turn-helix domain
EECMNDAG_01468 1.8e-117 insK L Integrase core domain
EECMNDAG_01469 4e-30 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01470 5.8e-130 V Abi-like protein
EECMNDAG_01472 1.4e-74
EECMNDAG_01473 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01474 5.5e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EECMNDAG_01475 1.6e-146 metQ P NLPA lipoprotein
EECMNDAG_01476 1.7e-156 S Sucrose-6F-phosphate phosphohydrolase
EECMNDAG_01477 1.8e-225 S Peptidase dimerisation domain
EECMNDAG_01478 7.7e-255 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EECMNDAG_01479 3.4e-155 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01480 6.6e-157 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01481 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
EECMNDAG_01482 3.4e-230 nagC GK ROK family
EECMNDAG_01483 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
EECMNDAG_01484 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EECMNDAG_01485 0.0 yjcE P Sodium/hydrogen exchanger family
EECMNDAG_01486 1.2e-154 ypfH S Phospholipase/Carboxylesterase
EECMNDAG_01487 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
EECMNDAG_01488 1.6e-16 U TraM recognition site of TraD and TraG
EECMNDAG_01491 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EECMNDAG_01492 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EECMNDAG_01493 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EECMNDAG_01494 2.6e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EECMNDAG_01495 1e-179 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EECMNDAG_01496 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
EECMNDAG_01497 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
EECMNDAG_01498 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
EECMNDAG_01499 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EECMNDAG_01500 3.8e-171 S Bacterial protein of unknown function (DUF881)
EECMNDAG_01501 4.2e-45 sbp S Protein of unknown function (DUF1290)
EECMNDAG_01502 1.6e-141 S Bacterial protein of unknown function (DUF881)
EECMNDAG_01503 5.9e-266 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EECMNDAG_01504 3.2e-116 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EECMNDAG_01505 1.8e-246
EECMNDAG_01506 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EECMNDAG_01507 8.2e-34
EECMNDAG_01508 1.5e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EECMNDAG_01509 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EECMNDAG_01510 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
EECMNDAG_01511 1.1e-69
EECMNDAG_01513 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
EECMNDAG_01514 0.0 pafB K WYL domain
EECMNDAG_01515 8e-54
EECMNDAG_01516 1.1e-50
EECMNDAG_01518 1.9e-75 S Pfam:CtkA_N
EECMNDAG_01519 1.4e-136 xylR GK ROK family
EECMNDAG_01520 2.7e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
EECMNDAG_01521 2.8e-125 4.1.1.44 S Carboxymuconolactone decarboxylase family
EECMNDAG_01522 2.1e-126 S Enoyl-(Acyl carrier protein) reductase
EECMNDAG_01523 1.3e-227 rutG F Permease family
EECMNDAG_01524 4.9e-156 3.1.3.73 G Phosphoglycerate mutase family
EECMNDAG_01525 1.5e-135 K helix_turn_helix, arabinose operon control protein
EECMNDAG_01526 8.4e-143 S Sulfite exporter TauE/SafE
EECMNDAG_01527 8.5e-70 S ECF transporter, substrate-specific component
EECMNDAG_01528 4.9e-79 2.7.1.48 F uridine kinase
EECMNDAG_01529 1e-157 korD 1.2.7.3 C Domain of unknown function (DUF362)
EECMNDAG_01530 1.6e-185 C Na H antiporter family protein
EECMNDAG_01531 1.1e-165 MA20_14895 S Conserved hypothetical protein 698
EECMNDAG_01532 9.7e-93
EECMNDAG_01533 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EECMNDAG_01534 8.4e-128 tkt 2.2.1.1 H Belongs to the transketolase family
EECMNDAG_01535 2.4e-184 pbuX F Permease family
EECMNDAG_01536 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
EECMNDAG_01537 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EECMNDAG_01538 9.3e-303 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EECMNDAG_01539 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
EECMNDAG_01540 1.5e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EECMNDAG_01541 1.4e-187 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EECMNDAG_01542 2.4e-145 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
EECMNDAG_01543 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
EECMNDAG_01544 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EECMNDAG_01545 8e-268 S Psort location Cytoplasmic, score 8.87
EECMNDAG_01547 2.1e-225 G Transmembrane secretion effector
EECMNDAG_01548 3.5e-120 K Bacterial regulatory proteins, tetR family
EECMNDAG_01549 1.1e-39 nrdH O Glutaredoxin
EECMNDAG_01550 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
EECMNDAG_01551 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EECMNDAG_01553 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EECMNDAG_01554 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EECMNDAG_01555 1.3e-29 EGP Major facilitator Superfamily
EECMNDAG_01556 2.5e-24 yhjX EGP Major facilitator Superfamily
EECMNDAG_01557 3.8e-195 S alpha beta
EECMNDAG_01558 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EECMNDAG_01559 1.1e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EECMNDAG_01560 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EECMNDAG_01561 9.1e-74 K Acetyltransferase (GNAT) domain
EECMNDAG_01563 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
EECMNDAG_01564 4.5e-132 S UPF0126 domain
EECMNDAG_01565 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
EECMNDAG_01566 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EECMNDAG_01567 1.5e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
EECMNDAG_01568 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
EECMNDAG_01569 6.9e-289 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
EECMNDAG_01570 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
EECMNDAG_01571 1.3e-235 F Psort location CytoplasmicMembrane, score 10.00
EECMNDAG_01572 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
EECMNDAG_01573 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EECMNDAG_01574 2e-74
EECMNDAG_01575 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
EECMNDAG_01576 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
EECMNDAG_01577 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EECMNDAG_01578 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
EECMNDAG_01579 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EECMNDAG_01580 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
EECMNDAG_01581 3.4e-44 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
EECMNDAG_01582 9.5e-29
EECMNDAG_01583 7.7e-101 K acetyltransferase
EECMNDAG_01584 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01585 3.6e-120 E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01586 1.1e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
EECMNDAG_01587 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
EECMNDAG_01588 2e-199 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EECMNDAG_01589 2e-155 metQ M NLPA lipoprotein
EECMNDAG_01590 1.9e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EECMNDAG_01591 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
EECMNDAG_01592 4.8e-221 mtnE 2.6.1.83 E Aminotransferase class I and II
EECMNDAG_01593 9.4e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EECMNDAG_01594 1.4e-43 XAC3035 O Glutaredoxin
EECMNDAG_01595 3.1e-127 XK27_08050 O prohibitin homologues
EECMNDAG_01596 1.7e-13 S Domain of unknown function (DUF4143)
EECMNDAG_01597 4.3e-75
EECMNDAG_01598 4.8e-134 V ATPases associated with a variety of cellular activities
EECMNDAG_01599 5.7e-147 M Conserved repeat domain
EECMNDAG_01600 2.6e-256 macB_8 V MacB-like periplasmic core domain
EECMNDAG_01601 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EECMNDAG_01602 1.2e-183 adh3 C Zinc-binding dehydrogenase
EECMNDAG_01603 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EECMNDAG_01604 6.4e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EECMNDAG_01605 8.8e-89 zur P Belongs to the Fur family
EECMNDAG_01606 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
EECMNDAG_01607 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
EECMNDAG_01608 9.1e-189 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
EECMNDAG_01609 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
EECMNDAG_01610 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
EECMNDAG_01611 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EECMNDAG_01612 1.6e-247 EGP Major facilitator Superfamily
EECMNDAG_01613 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
EECMNDAG_01614 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EECMNDAG_01615 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EECMNDAG_01616 2.5e-308 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
EECMNDAG_01617 1.5e-33
EECMNDAG_01618 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
EECMNDAG_01619 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EECMNDAG_01620 1.1e-226 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EECMNDAG_01621 6.5e-226 M Glycosyl transferase 4-like domain
EECMNDAG_01622 2.9e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
EECMNDAG_01624 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
EECMNDAG_01625 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EECMNDAG_01626 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EECMNDAG_01627 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EECMNDAG_01628 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EECMNDAG_01629 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EECMNDAG_01630 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EECMNDAG_01631 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
EECMNDAG_01632 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
EECMNDAG_01633 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
EECMNDAG_01634 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
EECMNDAG_01636 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
EECMNDAG_01637 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EECMNDAG_01638 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EECMNDAG_01639 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EECMNDAG_01640 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EECMNDAG_01641 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EECMNDAG_01642 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
EECMNDAG_01643 3.8e-282 arc O AAA ATPase forming ring-shaped complexes
EECMNDAG_01644 1.6e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
EECMNDAG_01645 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
EECMNDAG_01646 5.2e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
EECMNDAG_01647 1.7e-279 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EECMNDAG_01648 6.3e-140 C FMN binding
EECMNDAG_01649 1.8e-57
EECMNDAG_01650 1.4e-41 hup L Belongs to the bacterial histone-like protein family
EECMNDAG_01651 0.0 S Lysylphosphatidylglycerol synthase TM region
EECMNDAG_01652 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
EECMNDAG_01653 3.5e-277 S PGAP1-like protein
EECMNDAG_01654 1.3e-62
EECMNDAG_01655 5e-182 S von Willebrand factor (vWF) type A domain
EECMNDAG_01656 6.1e-191 S von Willebrand factor (vWF) type A domain
EECMNDAG_01657 3.6e-91
EECMNDAG_01658 4.7e-174 S Protein of unknown function DUF58
EECMNDAG_01659 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
EECMNDAG_01660 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EECMNDAG_01661 8.5e-77 S LytR cell envelope-related transcriptional attenuator
EECMNDAG_01662 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EECMNDAG_01664 1.3e-124
EECMNDAG_01665 6.8e-133 KT Response regulator receiver domain protein
EECMNDAG_01666 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EECMNDAG_01667 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
EECMNDAG_01668 1.2e-182 S Protein of unknown function (DUF3027)
EECMNDAG_01669 4.6e-188 uspA T Belongs to the universal stress protein A family
EECMNDAG_01670 0.0 clpC O ATPase family associated with various cellular activities (AAA)
EECMNDAG_01671 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
EECMNDAG_01672 1.6e-285 purR QT Purine catabolism regulatory protein-like family
EECMNDAG_01673 5e-246 proP EGP Sugar (and other) transporter
EECMNDAG_01674 4.6e-140 3.5.2.10 S Creatinine amidohydrolase
EECMNDAG_01675 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
EECMNDAG_01676 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
EECMNDAG_01677 1.6e-48 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EECMNDAG_01680 5.7e-23 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EECMNDAG_01682 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EECMNDAG_01683 1.9e-164 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
EECMNDAG_01684 2.4e-116 3.6.1.13 L NUDIX domain
EECMNDAG_01685 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EECMNDAG_01686 1.4e-212 ykiI
EECMNDAG_01688 1.6e-137 L Phage integrase family
EECMNDAG_01689 6.6e-69
EECMNDAG_01690 2.2e-24
EECMNDAG_01691 6.3e-67 rlfA S Protein of unknown function (DUF3800)
EECMNDAG_01692 1.7e-14
EECMNDAG_01693 1.4e-189 K Periplasmic binding protein domain
EECMNDAG_01694 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EECMNDAG_01695 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
EECMNDAG_01696 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EECMNDAG_01697 4.2e-144 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
EECMNDAG_01698 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01699 9.2e-151 pknD ET ABC transporter, substrate-binding protein, family 3
EECMNDAG_01700 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
EECMNDAG_01701 1.5e-109 pknD ET ABC transporter, substrate-binding protein, family 3
EECMNDAG_01702 2.2e-72 K helix_turn_helix ASNC type
EECMNDAG_01703 5.1e-142 V ABC transporter, ATP-binding protein
EECMNDAG_01704 0.0 MV MacB-like periplasmic core domain
EECMNDAG_01705 1.9e-130 K helix_turn_helix, Lux Regulon
EECMNDAG_01706 0.0 tcsS2 T Histidine kinase
EECMNDAG_01707 9.9e-271 pip 3.4.11.5 S alpha/beta hydrolase fold
EECMNDAG_01708 1.3e-190 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
EECMNDAG_01709 5e-199 gluD E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01710 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01711 2.6e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
EECMNDAG_01712 6.2e-137 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
EECMNDAG_01713 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
EECMNDAG_01714 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
EECMNDAG_01715 3.8e-284 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EECMNDAG_01717 1.1e-52
EECMNDAG_01718 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EECMNDAG_01719 3e-102 carD K CarD-like/TRCF domain
EECMNDAG_01720 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EECMNDAG_01721 2e-129 T Response regulator receiver domain protein
EECMNDAG_01722 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EECMNDAG_01723 2.5e-138 ctsW S Phosphoribosyl transferase domain
EECMNDAG_01724 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
EECMNDAG_01725 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
EECMNDAG_01726 3.3e-222
EECMNDAG_01727 0.0 S Glycosyl transferase, family 2
EECMNDAG_01728 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EECMNDAG_01729 5.7e-208 K Cell envelope-related transcriptional attenuator domain
EECMNDAG_01731 3.1e-170 K Cell envelope-related transcriptional attenuator domain
EECMNDAG_01732 0.0 D FtsK/SpoIIIE family
EECMNDAG_01733 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EECMNDAG_01734 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EECMNDAG_01735 2.7e-144 yplQ S Haemolysin-III related
EECMNDAG_01736 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EECMNDAG_01737 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
EECMNDAG_01738 7.2e-283 sdaA 4.3.1.17 E Serine dehydratase alpha chain
EECMNDAG_01739 1.8e-91
EECMNDAG_01741 3.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EECMNDAG_01742 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
EECMNDAG_01743 2.6e-71 divIC D Septum formation initiator
EECMNDAG_01744 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EECMNDAG_01745 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EECMNDAG_01746 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EECMNDAG_01747 1.2e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
EECMNDAG_01748 0.0 S Uncharacterised protein family (UPF0182)
EECMNDAG_01749 6.2e-140 S Domain of unknown function (DUF4194)
EECMNDAG_01750 5.7e-89 S G5
EECMNDAG_01751 3e-31 S G5
EECMNDAG_01753 2.2e-150 O Thioredoxin
EECMNDAG_01754 0.0 KLT Protein tyrosine kinase
EECMNDAG_01755 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
EECMNDAG_01756 1.6e-85 XCC2107 L SPTR Transposase
EECMNDAG_01757 4.3e-144 folP 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EECMNDAG_01758 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EECMNDAG_01759 9.5e-308 E ABC transporter, substrate-binding protein, family 5
EECMNDAG_01760 7.5e-259 EGP Major facilitator Superfamily
EECMNDAG_01761 1.1e-251 rarA L Recombination factor protein RarA
EECMNDAG_01762 1.5e-211 L DEAD DEAH box helicase
EECMNDAG_01763 2.7e-73 L DEAD DEAH box helicase
EECMNDAG_01764 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EECMNDAG_01765 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EECMNDAG_01766 1.1e-101 T Forkhead associated domain
EECMNDAG_01767 1.8e-103 B Belongs to the OprB family
EECMNDAG_01768 1.3e-162 3.1.3.16 T Sigma factor PP2C-like phosphatases
EECMNDAG_01769 0.0 E Transglutaminase-like superfamily
EECMNDAG_01770 8.3e-221 S Protein of unknown function DUF58
EECMNDAG_01771 3.1e-227 S ATPase family associated with various cellular activities (AAA)
EECMNDAG_01772 0.0 S Fibronectin type 3 domain
EECMNDAG_01773 1.7e-268 KLT Protein tyrosine kinase
EECMNDAG_01774 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
EECMNDAG_01775 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
EECMNDAG_01776 2.3e-246 G Major Facilitator Superfamily
EECMNDAG_01777 4.1e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EECMNDAG_01778 1.1e-38 csoR S Metal-sensitive transcriptional repressor
EECMNDAG_01779 0.0 G Bacterial Ig-like domain (group 4)
EECMNDAG_01780 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
EECMNDAG_01781 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
EECMNDAG_01782 9.3e-147 G Binding-protein-dependent transport system inner membrane component
EECMNDAG_01783 3.1e-167 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01784 3e-08 P Binding-protein-dependent transport system inner membrane component
EECMNDAG_01785 1.1e-242 G Bacterial extracellular solute-binding protein
EECMNDAG_01786 6.3e-193 K Periplasmic binding protein domain
EECMNDAG_01787 0.0 ubiB S ABC1 family
EECMNDAG_01788 1e-27 S granule-associated protein
EECMNDAG_01789 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EECMNDAG_01790 1.1e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
EECMNDAG_01791 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EECMNDAG_01792 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
EECMNDAG_01793 1e-54 glnB K Nitrogen regulatory protein P-II
EECMNDAG_01794 1.2e-236 amt U Ammonium Transporter Family
EECMNDAG_01795 3.3e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EECMNDAG_01796 2.3e-109 icaR K Bacterial regulatory proteins, tetR family
EECMNDAG_01797 5.7e-194 XK27_01805 M Glycosyltransferase like family 2
EECMNDAG_01798 5.6e-308 pepD E Peptidase family C69
EECMNDAG_01800 2.1e-185 3.4.22.70 M Sortase family
EECMNDAG_01802 1.1e-63 ydhQ 2.7.11.1 MU cell adhesion
EECMNDAG_01806 9.4e-10 S Helix-turn-helix domain
EECMNDAG_01807 7.9e-60 S Helix-turn-helix domain
EECMNDAG_01810 3.2e-181 L Phage integrase family
EECMNDAG_01811 1.5e-18

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)