ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKNIGPJH_00001 1.3e-36 S AAA domain
HKNIGPJH_00002 3.4e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HKNIGPJH_00003 1.3e-45 EGP Major facilitator Superfamily
HKNIGPJH_00004 6.3e-31 1.1.1.1 C Iron-containing alcohol dehydrogenase
HKNIGPJH_00005 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HKNIGPJH_00006 4.6e-74 E ABC transporter, substrate-binding protein, family 5
HKNIGPJH_00007 5.1e-96 EGP Major facilitator Superfamily
HKNIGPJH_00008 4e-13 S Domain of unknown function (DUF4143)
HKNIGPJH_00009 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HKNIGPJH_00010 4.4e-55 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKNIGPJH_00011 2.7e-117 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKNIGPJH_00012 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKNIGPJH_00013 2.1e-25 rpmI J Ribosomal protein L35
HKNIGPJH_00014 2.8e-148 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKNIGPJH_00015 2e-34
HKNIGPJH_00016 1.3e-246 S zinc finger
HKNIGPJH_00017 4.4e-71 S Bacterial PH domain
HKNIGPJH_00018 1.5e-76
HKNIGPJH_00019 8.4e-201 V Domain of unknown function (DUF3427)
HKNIGPJH_00020 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
HKNIGPJH_00021 8.1e-185 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HKNIGPJH_00022 9.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNIGPJH_00023 2.1e-91 S membrane transporter protein
HKNIGPJH_00024 2e-61 srtC 3.4.22.70 M Sortase family
HKNIGPJH_00025 3.8e-38 G ABC transporter substrate-binding protein
HKNIGPJH_00026 5e-42 G ABC transporter substrate-binding protein
HKNIGPJH_00027 1.6e-28 comM O Magnesium chelatase, subunit ChlI C-terminal
HKNIGPJH_00028 3.6e-23 yraN L Belongs to the UPF0102 family
HKNIGPJH_00029 2e-127 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKNIGPJH_00031 2.5e-153 clcA_2 P Voltage gated chloride channel
HKNIGPJH_00032 1.3e-218 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKNIGPJH_00033 3.5e-120 3.2.1.14 GH18 S Carbohydrate binding domain
HKNIGPJH_00034 0.0 T Diguanylate cyclase, GGDEF domain
HKNIGPJH_00035 2.3e-187 lacR K Transcriptional regulator, LacI family
HKNIGPJH_00036 8.7e-235 nagA 3.5.1.25 G Amidohydrolase family
HKNIGPJH_00037 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKNIGPJH_00038 2e-124 G Glycosyl hydrolase family 20, domain 2
HKNIGPJH_00039 9e-107 S AAA domain
HKNIGPJH_00040 3.1e-19
HKNIGPJH_00041 4.4e-197 EGP Major facilitator Superfamily
HKNIGPJH_00042 2.3e-31 T PhoQ Sensor
HKNIGPJH_00043 3.6e-168 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_00044 1.1e-149 3.4.14.13 M Glycosyltransferase like family 2
HKNIGPJH_00045 7.3e-25 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HKNIGPJH_00046 2.8e-70
HKNIGPJH_00048 7.5e-35 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKNIGPJH_00049 2.5e-35 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNIGPJH_00050 1.1e-166 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HKNIGPJH_00051 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKNIGPJH_00052 1.3e-250 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HKNIGPJH_00053 8.6e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HKNIGPJH_00054 1e-27 S granule-associated protein
HKNIGPJH_00055 0.0 ubiB S ABC1 family
HKNIGPJH_00056 1.1e-47 EGP Major facilitator Superfamily
HKNIGPJH_00057 6e-92 EGP Major facilitator Superfamily
HKNIGPJH_00058 0.0 murJ KLT MviN-like protein
HKNIGPJH_00059 4.1e-306 murJ KLT MviN-like protein
HKNIGPJH_00060 0.0 M Conserved repeat domain
HKNIGPJH_00061 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HKNIGPJH_00062 2e-171 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HKNIGPJH_00063 1.5e-208 srtA 3.4.22.70 M Sortase family
HKNIGPJH_00065 3.2e-153 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00066 2.9e-133 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_00067 1.8e-181 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00068 3.8e-101 abf G Glycosyl hydrolases family 43
HKNIGPJH_00069 1.1e-292 G Bacterial extracellular solute-binding protein
HKNIGPJH_00070 4.6e-169 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00071 8.3e-163 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00072 2.1e-183 G beta-fructofuranosidase activity
HKNIGPJH_00073 8.5e-101 S Protein of unknown function, DUF624
HKNIGPJH_00074 2.6e-25 S Beta-L-arabinofuranosidase, GH127
HKNIGPJH_00076 3.7e-105 L Resolvase, N terminal domain
HKNIGPJH_00077 5e-50 tesB I Thioesterase-like superfamily
HKNIGPJH_00078 6.2e-94 S Protein of unknown function (DUF3180)
HKNIGPJH_00079 2.6e-58 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKNIGPJH_00080 3.9e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HKNIGPJH_00081 3e-102 carD K CarD-like/TRCF domain
HKNIGPJH_00082 3.3e-142 mphA S Aminoglycoside phosphotransferase
HKNIGPJH_00083 3.6e-32 S Protein of unknown function (DUF3107)
HKNIGPJH_00084 1.8e-178 opcA G Glucose-6-phosphate dehydrogenase subunit
HKNIGPJH_00085 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HKNIGPJH_00086 8.4e-30 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKNIGPJH_00087 8.8e-139 S SdpI/YhfL protein family
HKNIGPJH_00088 1.9e-36 S Domain of unknown function (DUF4956)
HKNIGPJH_00089 4.9e-37 yliE T Putative diguanylate phosphodiesterase
HKNIGPJH_00090 1.9e-46 yliE T Putative diguanylate phosphodiesterase
HKNIGPJH_00091 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HKNIGPJH_00092 4.1e-101 V ABC transporter, ATP-binding protein
HKNIGPJH_00093 9e-17 K helix_turn_helix ASNC type
HKNIGPJH_00094 2.3e-116 S Protein of unknown function (DUF4125)
HKNIGPJH_00095 1.1e-16 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKNIGPJH_00096 1.1e-77 soxR K MerR, DNA binding
HKNIGPJH_00097 3.4e-17 yccF S Inner membrane component domain
HKNIGPJH_00098 5.9e-12
HKNIGPJH_00099 3e-132 M Conserved repeat domain
HKNIGPJH_00100 8.9e-101 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKNIGPJH_00101 4.5e-31
HKNIGPJH_00102 2.3e-164 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HKNIGPJH_00103 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKNIGPJH_00104 5.1e-63 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKNIGPJH_00105 2.3e-88 cat P Cation efflux family
HKNIGPJH_00106 8.6e-119 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKNIGPJH_00107 9.8e-15 G Major Facilitator Superfamily
HKNIGPJH_00108 1.7e-151 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HKNIGPJH_00109 2.9e-163 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKNIGPJH_00110 4.4e-144 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKNIGPJH_00111 3.7e-84 wcoI DM Psort location CytoplasmicMembrane, score
HKNIGPJH_00112 2.6e-149 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
HKNIGPJH_00113 4.3e-192 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HKNIGPJH_00114 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKNIGPJH_00115 2.2e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HKNIGPJH_00116 2.1e-293 S Amidohydrolase family
HKNIGPJH_00117 1.3e-78 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HKNIGPJH_00118 2.9e-69 ykiI
HKNIGPJH_00119 2.2e-31 ykiI
HKNIGPJH_00120 1.8e-33 P Bacterial extracellular solute-binding protein
HKNIGPJH_00121 2e-39 U Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00123 1.5e-19 macB_8 V MacB-like periplasmic core domain
HKNIGPJH_00124 2.1e-157 fadD1 6.2.1.3 I AMP-binding enzyme
HKNIGPJH_00125 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKNIGPJH_00126 2.5e-36
HKNIGPJH_00127 1.2e-67 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HKNIGPJH_00128 1.3e-60 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKNIGPJH_00129 3.5e-80 trxA2 O Tetratricopeptide repeat
HKNIGPJH_00130 8e-96 cyaA 4.6.1.1 S CYTH
HKNIGPJH_00131 2.7e-56 VP1224 V Psort location CytoplasmicMembrane, score 9.99
HKNIGPJH_00133 1e-93 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00134 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HKNIGPJH_00135 7e-118 3.2.1.97 GH101 G Glycosyl hydrolases family 43
HKNIGPJH_00136 8.7e-93 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKNIGPJH_00137 2.8e-117 GK ROK family
HKNIGPJH_00138 2.4e-189 K helix_turn _helix lactose operon repressor
HKNIGPJH_00139 1.7e-120 ftsK D FtsK SpoIIIE family protein
HKNIGPJH_00140 3.5e-52 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKNIGPJH_00141 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HKNIGPJH_00142 4.1e-242 T Diguanylate cyclase (GGDEF) domain protein
HKNIGPJH_00143 1.4e-126 L Protein of unknown function (DUF1524)
HKNIGPJH_00144 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HKNIGPJH_00145 8.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
HKNIGPJH_00146 8.9e-198 K helix_turn _helix lactose operon repressor
HKNIGPJH_00147 1.2e-70 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00148 1.4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKNIGPJH_00149 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKNIGPJH_00150 5.7e-77 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HKNIGPJH_00151 5.5e-29
HKNIGPJH_00152 2.1e-08 relB L RelB antitoxin
HKNIGPJH_00153 1.3e-18 3.4.17.13 E Rard protein
HKNIGPJH_00154 8e-100 mmuP E amino acid
HKNIGPJH_00155 2.1e-45 mmuP E amino acid
HKNIGPJH_00156 5.2e-167 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HKNIGPJH_00157 1.1e-95 lysX S Uncharacterised conserved protein (DUF2156)
HKNIGPJH_00158 1.2e-61 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKNIGPJH_00159 7.6e-63 S domain protein
HKNIGPJH_00160 9.2e-47 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNIGPJH_00161 8.8e-41 V ABC transporter, ATP-binding protein
HKNIGPJH_00162 0.0 MV MacB-like periplasmic core domain
HKNIGPJH_00163 1.9e-130 K helix_turn_helix, Lux Regulon
HKNIGPJH_00164 0.0 tcsS2 T Histidine kinase
HKNIGPJH_00165 1.7e-125 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKNIGPJH_00166 1.1e-106 S Phosphatidylethanolamine-binding protein
HKNIGPJH_00167 0.0 pepD E Peptidase family C69
HKNIGPJH_00168 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HKNIGPJH_00169 6.7e-62 S Macrophage migration inhibitory factor (MIF)
HKNIGPJH_00170 2.4e-95 S GtrA-like protein
HKNIGPJH_00171 9.9e-100 EGP Major facilitator Superfamily
HKNIGPJH_00172 1.4e-50 pknL 2.7.11.1 KLT PASTA
HKNIGPJH_00173 6.5e-58 T Forkhead associated domain
HKNIGPJH_00174 2.1e-35 metY 2.5.1.49 E Aminotransferase class-V
HKNIGPJH_00175 3.9e-78 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKNIGPJH_00176 3.3e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HKNIGPJH_00178 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKNIGPJH_00179 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
HKNIGPJH_00180 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKNIGPJH_00181 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKNIGPJH_00182 5.9e-143 QT PucR C-terminal helix-turn-helix domain
HKNIGPJH_00183 3.8e-116
HKNIGPJH_00184 2e-52
HKNIGPJH_00185 1.9e-138 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HKNIGPJH_00186 1.2e-86 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKNIGPJH_00187 1.7e-13 rpsB J Belongs to the universal ribosomal protein uS2 family
HKNIGPJH_00188 1.3e-129 cydD V ABC transporter transmembrane region
HKNIGPJH_00189 9e-127 dedA S SNARE associated Golgi protein
HKNIGPJH_00190 1.1e-101 1.1.1.65 C Aldo/keto reductase family
HKNIGPJH_00191 3.2e-09 S Protein of unknown function (DUF805)
HKNIGPJH_00192 2.9e-97
HKNIGPJH_00193 4.9e-100 L Tetratricopeptide repeat
HKNIGPJH_00194 2.1e-25 V ABC transporter, ATP-binding protein
HKNIGPJH_00195 3.5e-103 rpsA J Ribosomal protein S1
HKNIGPJH_00196 6.2e-160 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HKNIGPJH_00197 5.2e-96 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKNIGPJH_00198 1.2e-65
HKNIGPJH_00199 4.5e-13 I acetylesterase activity
HKNIGPJH_00200 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
HKNIGPJH_00201 2.2e-116 aspB E Aminotransferase class-V
HKNIGPJH_00202 3.4e-126 yxjG_1 E Psort location Cytoplasmic, score 8.87
HKNIGPJH_00203 1.9e-113 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKNIGPJH_00204 3.7e-139 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HKNIGPJH_00205 9.2e-86 XK27_10430 S NAD(P)H-binding
HKNIGPJH_00206 6.5e-36 Z012_06715 V FtsX-like permease family
HKNIGPJH_00208 8e-220 macB_2 V ABC transporter permease
HKNIGPJH_00209 4.2e-231 S Predicted membrane protein (DUF2318)
HKNIGPJH_00210 4.1e-92 tpd P Fe2+ transport protein
HKNIGPJH_00211 5.8e-295 efeU_1 P Iron permease FTR1 family
HKNIGPJH_00212 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HKNIGPJH_00213 2.6e-121 EGP Major facilitator Superfamily
HKNIGPJH_00215 7e-60 psp1 3.5.99.10 J Endoribonuclease L-PSP
HKNIGPJH_00216 2.6e-13 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HKNIGPJH_00217 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HKNIGPJH_00218 4.9e-131 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNIGPJH_00219 2.7e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNIGPJH_00220 8e-57 G Fic/DOC family
HKNIGPJH_00221 1.4e-25 3.1.3.27 E haloacid dehalogenase-like hydrolase
HKNIGPJH_00222 3.6e-48 pcrA 3.6.4.12 L DNA helicase
HKNIGPJH_00223 2.6e-71 divIC D Septum formation initiator
HKNIGPJH_00224 1e-31 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNIGPJH_00225 9e-121 U Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00226 7.9e-120 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKNIGPJH_00227 3.6e-174 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HKNIGPJH_00228 6.3e-63 T Forkhead associated domain
HKNIGPJH_00229 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HKNIGPJH_00230 4.8e-36
HKNIGPJH_00231 1.1e-92 flgA NO SAF
HKNIGPJH_00232 6.1e-30 fmdB S Putative regulatory protein
HKNIGPJH_00233 2e-99 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HKNIGPJH_00234 7.1e-46 argE E Peptidase dimerisation domain
HKNIGPJH_00235 5.2e-24 rodA D Belongs to the SEDS family
HKNIGPJH_00236 4e-34 rodA D Belongs to the SEDS family
HKNIGPJH_00237 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HKNIGPJH_00238 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HKNIGPJH_00239 1.2e-131 fhaA T Protein of unknown function (DUF2662)
HKNIGPJH_00240 4.5e-65 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKNIGPJH_00241 5.6e-143 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKNIGPJH_00242 2.2e-50 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKNIGPJH_00243 2.5e-269 G Bacterial extracellular solute-binding protein
HKNIGPJH_00244 1.7e-162 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00245 6.5e-148 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00246 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKNIGPJH_00247 6.8e-90 trxB1 1.8.1.9 C Thioredoxin domain
HKNIGPJH_00248 2.3e-229 yhjX EGP Major facilitator Superfamily
HKNIGPJH_00249 3.3e-43 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HKNIGPJH_00250 9.5e-35 lacS G Psort location CytoplasmicMembrane, score 10.00
HKNIGPJH_00251 3.4e-242 vex3 V ABC transporter permease
HKNIGPJH_00252 1.8e-157 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HKNIGPJH_00253 9.3e-147 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00254 3.1e-167 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00255 4e-07 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00256 1.1e-242 G Bacterial extracellular solute-binding protein
HKNIGPJH_00257 4.7e-93 K Periplasmic binding protein domain
HKNIGPJH_00258 3.1e-289 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HKNIGPJH_00259 1.7e-159 hisN 3.1.3.25 G Inositol monophosphatase family
HKNIGPJH_00260 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HKNIGPJH_00261 1.7e-279 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HKNIGPJH_00262 9.7e-141 C FMN binding
HKNIGPJH_00263 1.8e-57
HKNIGPJH_00264 1.4e-41 hup L Belongs to the bacterial histone-like protein family
HKNIGPJH_00265 2.9e-136 G Phosphoglycerate mutase family
HKNIGPJH_00266 6.6e-259 amyE G Bacterial extracellular solute-binding protein
HKNIGPJH_00267 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HKNIGPJH_00268 2.3e-114 amyE G Bacterial extracellular solute-binding protein
HKNIGPJH_00269 9.1e-253 recD2 3.6.4.12 L PIF1-like helicase
HKNIGPJH_00270 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKNIGPJH_00271 1.4e-98 L Single-strand binding protein family
HKNIGPJH_00272 0.0 pepO 3.4.24.71 O Peptidase family M13
HKNIGPJH_00273 3.6e-224 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNIGPJH_00274 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
HKNIGPJH_00275 2.1e-51 S Protein of unknown function (DUF2469)
HKNIGPJH_00276 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HKNIGPJH_00277 5.7e-51 S Psort location CytoplasmicMembrane, score
HKNIGPJH_00278 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
HKNIGPJH_00279 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HKNIGPJH_00280 2.4e-167 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HKNIGPJH_00281 2.3e-92 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKNIGPJH_00282 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKNIGPJH_00283 3.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
HKNIGPJH_00284 1.3e-101 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNIGPJH_00285 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKNIGPJH_00286 1.5e-39 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKNIGPJH_00287 6.6e-221 K helix_turn _helix lactose operon repressor
HKNIGPJH_00288 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00289 8e-126
HKNIGPJH_00290 1.8e-70 yknV V ABC transporter
HKNIGPJH_00291 3.2e-155 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKNIGPJH_00292 3.4e-35
HKNIGPJH_00293 1.4e-147 gluP 3.4.21.105 S Rhomboid family
HKNIGPJH_00294 3.1e-238 L ribosomal rna small subunit methyltransferase
HKNIGPJH_00295 1.8e-57 crgA D Involved in cell division
HKNIGPJH_00296 7.9e-65 S Bacterial protein of unknown function (DUF881)
HKNIGPJH_00297 6e-35 S Bacterial protein of unknown function (DUF881)
HKNIGPJH_00298 5.7e-21 E Transglutaminase-like superfamily
HKNIGPJH_00299 1.4e-84 E Transglutaminase-like superfamily
HKNIGPJH_00300 3.1e-220 S Protein of unknown function DUF58
HKNIGPJH_00301 2.5e-224 S ATPase family associated with various cellular activities (AAA)
HKNIGPJH_00302 1.1e-292 S Fibronectin type 3 domain
HKNIGPJH_00303 8.5e-107 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
HKNIGPJH_00304 2.1e-140 yidP K UTRA
HKNIGPJH_00305 5.6e-121 degU K helix_turn_helix, Lux Regulon
HKNIGPJH_00306 1.7e-264 tcsS3 KT PspC domain
HKNIGPJH_00307 4.2e-60 pspC KT PspC domain
HKNIGPJH_00308 1.8e-268 dnaK O Heat shock 70 kDa protein
HKNIGPJH_00309 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKNIGPJH_00310 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
HKNIGPJH_00311 4.5e-115 hspR K transcriptional regulator, MerR family
HKNIGPJH_00312 8.6e-47
HKNIGPJH_00313 3.3e-129 S HAD hydrolase, family IA, variant 3
HKNIGPJH_00314 3.4e-29 G Bacterial extracellular solute-binding protein
HKNIGPJH_00315 2.2e-190 K helix_turn _helix lactose operon repressor
HKNIGPJH_00316 0.0 M probably involved in cell wall
HKNIGPJH_00317 0.0 S LPXTG-motif cell wall anchor domain protein
HKNIGPJH_00318 2.2e-277 M LPXTG-motif cell wall anchor domain protein
HKNIGPJH_00319 5.9e-164 3.4.22.70 M Sortase family
HKNIGPJH_00320 3.8e-34 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKNIGPJH_00321 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKNIGPJH_00322 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKNIGPJH_00323 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKNIGPJH_00324 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKNIGPJH_00325 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
HKNIGPJH_00326 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKNIGPJH_00327 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HKNIGPJH_00328 5.9e-199 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKNIGPJH_00329 9.9e-275 cycA E Amino acid permease
HKNIGPJH_00330 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKNIGPJH_00331 2.6e-129 thiF 2.7.7.73, 2.7.7.80 H ThiF family
HKNIGPJH_00332 1.9e-26 thiS 2.8.1.10 H ThiS family
HKNIGPJH_00333 0.0 S L,D-transpeptidase catalytic domain
HKNIGPJH_00334 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKNIGPJH_00335 8.7e-229 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HKNIGPJH_00336 3.2e-57 I alpha/beta hydrolase fold
HKNIGPJH_00337 3.9e-31 I alpha/beta hydrolase fold
HKNIGPJH_00338 2.8e-145 cobB2 K Sir2 family
HKNIGPJH_00339 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HKNIGPJH_00340 1.8e-265 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKNIGPJH_00341 6.3e-268 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKNIGPJH_00342 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HKNIGPJH_00343 5e-91
HKNIGPJH_00344 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKNIGPJH_00345 1.3e-113 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HKNIGPJH_00346 7.9e-188 ansA 3.5.1.1 EJ Asparaginase
HKNIGPJH_00347 0.0 cadA P E1-E2 ATPase
HKNIGPJH_00348 1.1e-44 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HKNIGPJH_00349 2.1e-106 kup P Transport of potassium into the cell
HKNIGPJH_00350 7.7e-185 tatD L TatD related DNase
HKNIGPJH_00351 0.0 G Alpha-L-arabinofuranosidase C-terminus
HKNIGPJH_00352 2e-178 S Endonuclease/Exonuclease/phosphatase family
HKNIGPJH_00353 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKNIGPJH_00354 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HKNIGPJH_00355 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKNIGPJH_00356 2.3e-150 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKNIGPJH_00357 1.4e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HKNIGPJH_00358 2.3e-60 recG 3.6.4.12 L helicase superfamily c-terminal domain
HKNIGPJH_00359 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKNIGPJH_00360 7.3e-106
HKNIGPJH_00361 4.4e-189 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKNIGPJH_00362 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
HKNIGPJH_00363 3.2e-119 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKNIGPJH_00364 6e-39 ptsH G PTS HPr component phosphorylation site
HKNIGPJH_00365 2.7e-183 K helix_turn _helix lactose operon repressor
HKNIGPJH_00366 1.1e-193 holB 2.7.7.7 L DNA polymerase III
HKNIGPJH_00367 1.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKNIGPJH_00368 4.9e-19 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKNIGPJH_00369 1.7e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HKNIGPJH_00370 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HKNIGPJH_00371 5.8e-177 T Protein tyrosine kinase
HKNIGPJH_00372 7.9e-149 pbpA M penicillin-binding protein
HKNIGPJH_00373 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKNIGPJH_00374 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00375 1.5e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00376 1.4e-195 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HKNIGPJH_00377 7.7e-151 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HKNIGPJH_00378 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HKNIGPJH_00379 1.8e-234 malE G Bacterial extracellular solute-binding protein
HKNIGPJH_00380 3e-101 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HKNIGPJH_00381 7.2e-56 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HKNIGPJH_00382 6e-120 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HKNIGPJH_00383 2.7e-29 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HKNIGPJH_00384 1.2e-279 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HKNIGPJH_00385 2.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNIGPJH_00386 2.6e-61
HKNIGPJH_00387 1.1e-197 K helix_turn _helix lactose operon repressor
HKNIGPJH_00388 1.6e-140 3.1.3.16 T Sigma factor PP2C-like phosphatases
HKNIGPJH_00389 4.8e-104 B Belongs to the OprB family
HKNIGPJH_00390 1.1e-101 T Forkhead associated domain
HKNIGPJH_00391 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNIGPJH_00392 1.7e-123 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00393 4.4e-164 G ABC transporter permease
HKNIGPJH_00394 2.8e-171 2.7.1.2 GK ROK family
HKNIGPJH_00395 1.1e-101 G Glycosyl hydrolase family 20, domain 2
HKNIGPJH_00396 2.6e-138 G Glycosyl hydrolase family 20, domain 2
HKNIGPJH_00397 8e-91 jag S Putative single-stranded nucleic acids-binding domain
HKNIGPJH_00398 2.3e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HKNIGPJH_00399 1.3e-171 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HKNIGPJH_00400 6.8e-203 parB K Belongs to the ParB family
HKNIGPJH_00401 1.7e-96 G Bacterial extracellular solute-binding protein
HKNIGPJH_00402 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HKNIGPJH_00403 1.5e-115 S Protein of unknown function, DUF624
HKNIGPJH_00404 4.5e-73 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HKNIGPJH_00405 0.0 KLT Lanthionine synthetase C-like protein
HKNIGPJH_00406 6.5e-184 KLT serine threonine protein kinase
HKNIGPJH_00407 2.6e-135 3.6.3.44 V ABC transporter
HKNIGPJH_00408 1.4e-93 msbA2 3.6.3.44 V ABC transporter transmembrane region
HKNIGPJH_00409 1.6e-176 plsC2 2.3.1.51 I Phosphate acyltransferases
HKNIGPJH_00410 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKNIGPJH_00411 8.3e-51 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HKNIGPJH_00412 4.1e-69 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKNIGPJH_00413 5.5e-141 cpaE D bacterial-type flagellum organization
HKNIGPJH_00414 6.1e-185 cpaF U Type II IV secretion system protein
HKNIGPJH_00415 6.9e-125 U Type ii secretion system
HKNIGPJH_00416 2.2e-88 gspF NU Type II secretion system (T2SS), protein F
HKNIGPJH_00417 0.0 pip S YhgE Pip domain protein
HKNIGPJH_00418 1.3e-93 pip S YhgE Pip domain protein
HKNIGPJH_00419 6.2e-34 pip S YhgE Pip domain protein
HKNIGPJH_00420 3.7e-33 pip S YhgE Pip domain protein
HKNIGPJH_00421 6e-112 S Short C-terminal domain
HKNIGPJH_00422 1.1e-61 S Protein of unknown function (DUF4230)
HKNIGPJH_00424 1.6e-33
HKNIGPJH_00425 4.2e-38
HKNIGPJH_00426 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HKNIGPJH_00427 5.4e-100 CE10 I Belongs to the type-B carboxylesterase lipase family
HKNIGPJH_00428 1e-71 CE10 I Belongs to the type-B carboxylesterase lipase family
HKNIGPJH_00429 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HKNIGPJH_00430 1.4e-233 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HKNIGPJH_00431 3.7e-57 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00432 6.9e-130 pyk 2.7.1.40 G Pyruvate kinase
HKNIGPJH_00435 8.9e-43 K Psort location Cytoplasmic, score
HKNIGPJH_00436 8.6e-19
HKNIGPJH_00438 1.2e-129
HKNIGPJH_00439 3.4e-34
HKNIGPJH_00440 2.9e-237 5.4.99.9 H Flavin containing amine oxidoreductase
HKNIGPJH_00441 3.5e-133 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HKNIGPJH_00442 4.3e-58 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HKNIGPJH_00443 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKNIGPJH_00444 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKNIGPJH_00445 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKNIGPJH_00446 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKNIGPJH_00447 2.2e-57 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKNIGPJH_00448 2.1e-256 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HKNIGPJH_00449 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HKNIGPJH_00450 3.7e-134 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKNIGPJH_00451 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HKNIGPJH_00452 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKNIGPJH_00453 3.8e-240 fadD 6.2.1.3 I AMP-binding enzyme
HKNIGPJH_00454 1.5e-156 pknD ET ABC transporter, substrate-binding protein, family 3
HKNIGPJH_00455 1e-35 pknD ET ABC transporter, substrate-binding protein, family 3
HKNIGPJH_00456 9.2e-151 pknD ET ABC transporter, substrate-binding protein, family 3
HKNIGPJH_00457 1.5e-146 yecS E Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00460 2.4e-22 2.7.13.3 T Histidine kinase
HKNIGPJH_00461 1.2e-36 K helix_turn_helix, Lux Regulon
HKNIGPJH_00462 3e-26 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKNIGPJH_00463 2.7e-144 yplQ S Haemolysin-III related
HKNIGPJH_00464 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKNIGPJH_00465 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HKNIGPJH_00466 6.5e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HKNIGPJH_00467 1.1e-45
HKNIGPJH_00468 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKNIGPJH_00469 2.4e-116
HKNIGPJH_00471 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HKNIGPJH_00472 9.2e-62 lacY P LacY proton/sugar symporter
HKNIGPJH_00473 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HKNIGPJH_00474 8.5e-143 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00475 1.2e-241 pccB I Carboxyl transferase domain
HKNIGPJH_00476 1.5e-41 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_00477 1.5e-83 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_00478 6.8e-153 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_00479 7.3e-109 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_00480 6.9e-130 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HKNIGPJH_00481 1e-54 glnB K Nitrogen regulatory protein P-II
HKNIGPJH_00482 1.2e-236 amt U Ammonium Transporter Family
HKNIGPJH_00483 5.9e-118 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKNIGPJH_00484 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKNIGPJH_00485 5.2e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HKNIGPJH_00486 5.5e-133 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKNIGPJH_00487 7.3e-169 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKNIGPJH_00488 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKNIGPJH_00489 8.8e-45 tkt 2.2.1.1 H Belongs to the transketolase family
HKNIGPJH_00490 2e-67 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKNIGPJH_00491 8.8e-83 mhpC I Alpha/beta hydrolase family
HKNIGPJH_00492 2.9e-116 F Domain of unknown function (DUF4916)
HKNIGPJH_00493 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HKNIGPJH_00494 1.6e-169 S G5
HKNIGPJH_00495 4.6e-88
HKNIGPJH_00496 2.2e-170 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HKNIGPJH_00497 1.6e-247 EGP Major facilitator Superfamily
HKNIGPJH_00498 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HKNIGPJH_00499 3.3e-62 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HKNIGPJH_00500 2.5e-264 KLT Protein tyrosine kinase
HKNIGPJH_00501 3.2e-139 S Fibronectin type 3 domain
HKNIGPJH_00502 3.7e-137 S LPXTG-motif cell wall anchor domain protein
HKNIGPJH_00503 6.3e-293 S LPXTG-motif cell wall anchor domain protein
HKNIGPJH_00504 8.1e-84 3.2.1.37 GH43 G Glycosyl hydrolases family 43
HKNIGPJH_00505 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKNIGPJH_00506 2.3e-108 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00507 1.8e-223 G Bacterial extracellular solute-binding protein
HKNIGPJH_00508 7e-181 K helix_turn _helix lactose operon repressor
HKNIGPJH_00510 9.4e-77 K Psort location Cytoplasmic, score
HKNIGPJH_00511 4.1e-147 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HKNIGPJH_00512 3e-162
HKNIGPJH_00513 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HKNIGPJH_00514 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HKNIGPJH_00515 3.6e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HKNIGPJH_00516 1.5e-155 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HKNIGPJH_00517 2.5e-49 lipA I Hydrolase, alpha beta domain protein
HKNIGPJH_00518 0.0 mdlA2 V ABC transporter
HKNIGPJH_00519 1.2e-163 yknV V ABC transporter
HKNIGPJH_00520 3.8e-63 glxR K helix_turn_helix, cAMP Regulatory protein
HKNIGPJH_00521 4.5e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HKNIGPJH_00522 2.9e-86 J TM2 domain
HKNIGPJH_00523 8.4e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKNIGPJH_00524 4e-192 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKNIGPJH_00525 3.9e-137 ctpE P E1-E2 ATPase
HKNIGPJH_00526 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HKNIGPJH_00527 2.6e-167 ftsE D Cell division ATP-binding protein FtsE
HKNIGPJH_00528 3.2e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKNIGPJH_00529 1.8e-308 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HKNIGPJH_00531 9.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HKNIGPJH_00532 1.3e-223 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00533 1.2e-176 yjjP S Threonine/Serine exporter, ThrE
HKNIGPJH_00534 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKNIGPJH_00535 8e-196 S Uncharacterized conserved protein (DUF2183)
HKNIGPJH_00536 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HKNIGPJH_00537 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNIGPJH_00538 3.4e-156 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HKNIGPJH_00539 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HKNIGPJH_00540 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKNIGPJH_00541 4.9e-49 O Thioredoxin
HKNIGPJH_00542 0.0 KLT Protein tyrosine kinase
HKNIGPJH_00543 1e-46 3.2.1.21 GH3 G Fibronectin type III-like domain
HKNIGPJH_00544 4.4e-237 G MFS/sugar transport protein
HKNIGPJH_00545 1.4e-117 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNIGPJH_00546 1.7e-137 lmrA2 V ABC transporter transmembrane region
HKNIGPJH_00547 6.7e-26 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKNIGPJH_00548 1.8e-52 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKNIGPJH_00549 1.6e-187 galM 5.1.3.3 G Aldose 1-epimerase
HKNIGPJH_00550 1.2e-36
HKNIGPJH_00551 1.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HKNIGPJH_00552 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HKNIGPJH_00553 3.4e-97 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HKNIGPJH_00554 7.6e-129 E Psort location Cytoplasmic, score 8.87
HKNIGPJH_00555 1.4e-133 yebE S DUF218 domain
HKNIGPJH_00556 5.3e-106 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKNIGPJH_00557 5.3e-41 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HKNIGPJH_00558 3.6e-63 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HKNIGPJH_00559 8e-188 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKNIGPJH_00560 2.7e-91 mraZ K Belongs to the MraZ family
HKNIGPJH_00561 5.5e-10 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNIGPJH_00562 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNIGPJH_00563 1.4e-29 E Receptor family ligand binding region
HKNIGPJH_00564 1.1e-195 K helix_turn _helix lactose operon repressor
HKNIGPJH_00565 1.3e-158 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HKNIGPJH_00566 6.1e-86 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKNIGPJH_00567 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HKNIGPJH_00568 1.4e-215 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKNIGPJH_00569 7.3e-101 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00570 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HKNIGPJH_00571 3.1e-62 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00572 3.8e-75 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HKNIGPJH_00573 2.6e-109 S LytR cell envelope-related transcriptional attenuator
HKNIGPJH_00574 1.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKNIGPJH_00575 1.3e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKNIGPJH_00576 4e-39 S G5
HKNIGPJH_00577 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00578 3e-206 abfA1 3.2.1.55 GH51 G arabinose metabolic process
HKNIGPJH_00579 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKNIGPJH_00580 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKNIGPJH_00581 3.4e-137 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKNIGPJH_00582 2.9e-145 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNIGPJH_00583 1.4e-242 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HKNIGPJH_00584 6.8e-112 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HKNIGPJH_00585 1.2e-32 S Uncharacterised protein family (UPF0182)
HKNIGPJH_00586 0.0 S Uncharacterised protein family (UPF0182)
HKNIGPJH_00587 6.8e-83 S Lysylphosphatidylglycerol synthase TM region
HKNIGPJH_00588 3e-35 S Lysylphosphatidylglycerol synthase TM region
HKNIGPJH_00589 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HKNIGPJH_00590 2.1e-11 S PGAP1-like protein
HKNIGPJH_00591 2.6e-79 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNIGPJH_00592 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNIGPJH_00593 2.7e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HKNIGPJH_00594 1.6e-123 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HKNIGPJH_00595 3.3e-146 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HKNIGPJH_00596 1.2e-45 aspB E Aminotransferase class-V
HKNIGPJH_00597 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HKNIGPJH_00598 2.2e-99 tmp1 S Domain of unknown function (DUF4391)
HKNIGPJH_00600 6.1e-82 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HKNIGPJH_00601 9e-95 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HKNIGPJH_00602 1.9e-112 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HKNIGPJH_00603 2.5e-13 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNIGPJH_00604 1.9e-40 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNIGPJH_00605 6.5e-85 G Transporter major facilitator family protein
HKNIGPJH_00606 6e-195 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKNIGPJH_00607 2.8e-105 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00608 1.1e-102 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HKNIGPJH_00609 1.2e-126 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNIGPJH_00610 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HKNIGPJH_00611 2.1e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKNIGPJH_00612 1.9e-106 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNIGPJH_00613 3e-251 T GHKL domain
HKNIGPJH_00614 7.2e-152 T LytTr DNA-binding domain
HKNIGPJH_00615 8.2e-37 S Calcineurin-like phosphoesterase
HKNIGPJH_00616 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HKNIGPJH_00617 3.5e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKNIGPJH_00618 2.2e-35 moxR S ATPase family associated with various cellular activities (AAA)
HKNIGPJH_00619 5.5e-175 S Protein of unknown function DUF58
HKNIGPJH_00620 1.4e-90
HKNIGPJH_00621 4.7e-191 S von Willebrand factor (vWF) type A domain
HKNIGPJH_00622 8.8e-57 S von Willebrand factor (vWF) type A domain
HKNIGPJH_00623 0.0 S Protein of unknown function (DUF975)
HKNIGPJH_00624 8.6e-137 S Putative ABC-transporter type IV
HKNIGPJH_00625 7.1e-39 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNIGPJH_00626 4.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
HKNIGPJH_00627 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HKNIGPJH_00628 1.8e-248 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKNIGPJH_00629 1.3e-14
HKNIGPJH_00630 1.2e-20
HKNIGPJH_00631 3.1e-74 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKNIGPJH_00632 3.5e-252 yhjE EGP Sugar (and other) transporter
HKNIGPJH_00633 5.6e-103 scrT G Transporter major facilitator family protein
HKNIGPJH_00634 2.6e-21 rmuC S RmuC family
HKNIGPJH_00635 4.4e-134 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
HKNIGPJH_00636 3.9e-276 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNIGPJH_00637 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HKNIGPJH_00638 9.7e-222
HKNIGPJH_00639 4.2e-89 S Glycosyl transferase, family 2
HKNIGPJH_00640 1.1e-36 msmF G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00641 4e-153 rafG G ABC transporter permease
HKNIGPJH_00642 5.8e-106 S Protein of unknown function, DUF624
HKNIGPJH_00643 2.9e-13 S Transposon-encoded protein TnpV
HKNIGPJH_00644 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
HKNIGPJH_00645 5.5e-48 U TadE-like protein
HKNIGPJH_00646 1.1e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
HKNIGPJH_00647 4.9e-218 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HKNIGPJH_00648 1.6e-193 S Psort location CytoplasmicMembrane, score
HKNIGPJH_00649 1.1e-96 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00650 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HKNIGPJH_00651 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKNIGPJH_00652 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HKNIGPJH_00653 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HKNIGPJH_00654 3.9e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKNIGPJH_00655 2.4e-115
HKNIGPJH_00656 3.7e-301 S Calcineurin-like phosphoesterase
HKNIGPJH_00657 1.1e-135 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKNIGPJH_00658 1.7e-161 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HKNIGPJH_00659 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKNIGPJH_00660 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKNIGPJH_00661 4.6e-19 3.1.21.3 V DivIVA protein
HKNIGPJH_00662 1.7e-31 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HKNIGPJH_00663 3.4e-121 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
HKNIGPJH_00664 2.1e-81 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
HKNIGPJH_00665 1.1e-113 vex2 V ABC transporter, ATP-binding protein
HKNIGPJH_00666 4.3e-11 uspA T Belongs to the universal stress protein A family
HKNIGPJH_00667 1.2e-182 S Protein of unknown function (DUF3027)
HKNIGPJH_00668 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
HKNIGPJH_00669 5.6e-203 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKNIGPJH_00670 3.8e-45 S Fibronectin type 3 domain
HKNIGPJH_00671 7.6e-46 S Fibronectin type 3 domain
HKNIGPJH_00672 2.7e-52 S Fibronectin type 3 domain
HKNIGPJH_00673 4.1e-23 S Fibronectin type 3 domain
HKNIGPJH_00674 3.7e-67 S Fibronectin type 3 domain
HKNIGPJH_00675 6.4e-102 yghZ C Aldo/keto reductase family
HKNIGPJH_00676 3.2e-58 S Protein of unknown function (DUF3039)
HKNIGPJH_00677 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKNIGPJH_00678 8.5e-134
HKNIGPJH_00679 1.8e-113 yceD S Uncharacterized ACR, COG1399
HKNIGPJH_00680 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKNIGPJH_00681 5.7e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKNIGPJH_00682 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HKNIGPJH_00683 2.8e-91 ilvN 2.2.1.6 E ACT domain
HKNIGPJH_00684 3e-93
HKNIGPJH_00685 0.0 yjjK S ABC transporter
HKNIGPJH_00686 1.6e-151 guaA1 6.3.5.2 F Peptidase C26
HKNIGPJH_00687 1e-301 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKNIGPJH_00688 1.6e-94
HKNIGPJH_00693 3.3e-101 S Protein of unknown function DUF45
HKNIGPJH_00694 1.4e-184 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKNIGPJH_00695 2.4e-98 ytfL P Transporter associated domain
HKNIGPJH_00696 8.7e-67 prs 2.7.6.1 F Belongs to the ribose-phosphate pyrophosphokinase family
HKNIGPJH_00697 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKNIGPJH_00698 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKNIGPJH_00699 3.3e-106 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKNIGPJH_00700 1.7e-57 dapE 3.5.1.18 E Peptidase dimerisation domain
HKNIGPJH_00701 5.2e-19 rne 3.1.26.12 J Ribonuclease E/G family
HKNIGPJH_00702 1e-161 rne 3.1.26.12 J Ribonuclease E/G family
HKNIGPJH_00703 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HKNIGPJH_00704 2.7e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNIGPJH_00705 2.2e-162 M Bacterial capsule synthesis protein PGA_cap
HKNIGPJH_00706 6.5e-51 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
HKNIGPJH_00707 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00708 1.6e-207 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKNIGPJH_00712 7.7e-171 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKNIGPJH_00713 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HKNIGPJH_00714 1.2e-154 ypfH S Phospholipase/Carboxylesterase
HKNIGPJH_00715 0.0 yjcE P Sodium/hydrogen exchanger family
HKNIGPJH_00716 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKNIGPJH_00717 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HKNIGPJH_00718 1.5e-230 nagC GK ROK family
HKNIGPJH_00719 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
HKNIGPJH_00720 6.6e-157 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00721 2.6e-155 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00722 1.4e-110 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKNIGPJH_00723 3.2e-107 G Transmembrane secretion effector
HKNIGPJH_00724 4.5e-14 V MATE efflux family protein
HKNIGPJH_00726 3.6e-268 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_00727 5.8e-17 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HKNIGPJH_00728 2.7e-41 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKNIGPJH_00729 3.8e-195 S alpha beta
HKNIGPJH_00730 1.3e-25 yhjX EGP Major facilitator Superfamily
HKNIGPJH_00731 9.4e-35 EGP Major facilitator Superfamily
HKNIGPJH_00733 7.1e-43 gcvR T Belongs to the UPF0237 family
HKNIGPJH_00734 1.1e-23 lmrB EGP Major facilitator Superfamily
HKNIGPJH_00735 1.5e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HKNIGPJH_00736 1.5e-143 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HKNIGPJH_00737 6e-76 MA20_36090 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_00738 5.9e-230 MA20_36090 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_00739 3.6e-195
HKNIGPJH_00740 2.7e-180
HKNIGPJH_00741 5.9e-120 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKNIGPJH_00742 2.1e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNIGPJH_00743 5e-128 V ATPases associated with a variety of cellular activities
HKNIGPJH_00744 1.7e-75 E ABC transporter, substrate-binding protein, family 5
HKNIGPJH_00745 8.7e-133 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HKNIGPJH_00746 1.6e-26 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HKNIGPJH_00747 9.9e-160 S Patatin-like phospholipase
HKNIGPJH_00749 2.1e-39 S Tetratricopeptide repeat
HKNIGPJH_00750 2e-17 S Tetratricopeptide repeat
HKNIGPJH_00751 6.9e-104 S Tetratricopeptide repeat
HKNIGPJH_00752 2.7e-45 S Tetratricopeptide repeat
HKNIGPJH_00753 6.5e-249 cydD V ABC transporter transmembrane region
HKNIGPJH_00754 1.5e-35 rpmE J Binds the 23S rRNA
HKNIGPJH_00756 6.8e-226 xylR GK ROK family
HKNIGPJH_00757 2.1e-118 pip S YhgE Pip domain protein
HKNIGPJH_00758 2.1e-88 K Psort location Cytoplasmic, score 8.87
HKNIGPJH_00759 1.1e-61 S FMN_bind
HKNIGPJH_00760 1.6e-143 macB V ABC transporter, ATP-binding protein
HKNIGPJH_00761 2.3e-93 pilT NU Type II/IV secretion system protein
HKNIGPJH_00762 0.0
HKNIGPJH_00763 4e-62 scrT G Transporter major facilitator family protein
HKNIGPJH_00764 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00765 2.4e-161 amyD3 P Binding-protein-dependent transport system inner membrane component
HKNIGPJH_00766 2.5e-28 G Bacterial extracellular solute-binding protein
HKNIGPJH_00767 2.7e-41 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HKNIGPJH_00768 2.3e-45 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HKNIGPJH_00769 2.6e-177 S Sucrose-6F-phosphate phosphohydrolase
HKNIGPJH_00770 2.4e-32 secG U Preprotein translocase SecG subunit
HKNIGPJH_00771 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKNIGPJH_00772 9.5e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKNIGPJH_00773 3e-10
HKNIGPJH_00774 2.6e-300 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HKNIGPJH_00775 5.6e-59
HKNIGPJH_00776 2.1e-260 G Bacterial extracellular solute-binding protein
HKNIGPJH_00777 3.9e-187 K helix_turn _helix lactose operon repressor
HKNIGPJH_00778 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
HKNIGPJH_00779 2.2e-37 4.2.1.53 S MCRA family
HKNIGPJH_00780 9.1e-155 4.2.1.53 S MCRA family
HKNIGPJH_00781 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
HKNIGPJH_00782 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKNIGPJH_00783 5.9e-266 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKNIGPJH_00784 1.6e-141 S Bacterial protein of unknown function (DUF881)
HKNIGPJH_00785 4.2e-45 sbp S Protein of unknown function (DUF1290)
HKNIGPJH_00786 1.7e-44 M Mechanosensitive ion channel
HKNIGPJH_00787 1.1e-177 S CAAX protease self-immunity
HKNIGPJH_00788 2.6e-214 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKNIGPJH_00789 0.0 S Psort location CytoplasmicMembrane, score 9.99
HKNIGPJH_00790 1.6e-102 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKNIGPJH_00791 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HKNIGPJH_00792 2e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKNIGPJH_00793 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
HKNIGPJH_00794 2.2e-96 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKNIGPJH_00795 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKNIGPJH_00796 4.1e-23 XK27_06785 V ABC transporter
HKNIGPJH_00797 8.8e-160 yicL EG EamA-like transporter family
HKNIGPJH_00798 3.9e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
HKNIGPJH_00799 4.1e-71 lmrA2 V ABC transporter transmembrane region
HKNIGPJH_00800 2.9e-257 lmrA1 V ABC transporter, ATP-binding protein
HKNIGPJH_00801 1.7e-61 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKNIGPJH_00802 2.4e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKNIGPJH_00803 1.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKNIGPJH_00804 3e-60 S Thiamine-binding protein
HKNIGPJH_00805 1.7e-151 S Protein of unknown function (DUF3710)
HKNIGPJH_00806 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HKNIGPJH_00807 1.3e-48 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HKNIGPJH_00808 8.3e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKNIGPJH_00809 7.8e-148 S phosphoesterase or phosphohydrolase
HKNIGPJH_00810 2.5e-128
HKNIGPJH_00811 1.1e-189 eccCa D FtsK/SpoIIIE family
HKNIGPJH_00812 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKNIGPJH_00813 1.1e-79 lmrB U Major Facilitator Superfamily
HKNIGPJH_00814 1.4e-43 K helix_turn_helix, mercury resistance
HKNIGPJH_00815 6.3e-14 K helix_turn_helix, mercury resistance
HKNIGPJH_00816 2.9e-87 K Periplasmic binding protein domain
HKNIGPJH_00817 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HKNIGPJH_00818 3.2e-152 S Glycosyl transferase, family 2
HKNIGPJH_00819 6.7e-51 S Glycosyl transferase, family 2
HKNIGPJH_00820 8.9e-300 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HKNIGPJH_00821 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HKNIGPJH_00822 1.8e-215 ybiR P Citrate transporter
HKNIGPJH_00823 1.2e-169 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKNIGPJH_00824 4.9e-139 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKNIGPJH_00825 4.5e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKNIGPJH_00826 1.5e-87
HKNIGPJH_00827 5.6e-92 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKNIGPJH_00828 3.6e-31 S Protein of unknown function (DUF805)
HKNIGPJH_00829 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HKNIGPJH_00830 5.6e-219 S Domain of unknown function (DUF5067)
HKNIGPJH_00833 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKNIGPJH_00834 1.9e-127 gntR K FCD
HKNIGPJH_00835 5.6e-79 gntK 2.7.1.12 F Shikimate kinase
HKNIGPJH_00836 2e-76 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HKNIGPJH_00837 3.1e-62 kup P Transport of potassium into the cell
HKNIGPJH_00838 2.3e-167 S Glutamine amidotransferase domain
HKNIGPJH_00839 9.6e-149 T HD domain
HKNIGPJH_00840 7.5e-63 lmrB U Major Facilitator Superfamily
HKNIGPJH_00841 4.6e-158 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HKNIGPJH_00842 7.8e-56 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HKNIGPJH_00843 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKNIGPJH_00844 1.1e-17 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKNIGPJH_00845 1.1e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
HKNIGPJH_00847 2.2e-49 yocS S SBF-like CPA transporter family (DUF4137)
HKNIGPJH_00848 2.2e-16 yocS S SBF-like CPA transporter family (DUF4137)
HKNIGPJH_00849 2.2e-128 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HKNIGPJH_00850 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
HKNIGPJH_00851 6.1e-191 nusA K Participates in both transcription termination and antitermination
HKNIGPJH_00852 2e-102
HKNIGPJH_00854 5.7e-45 E Transglutaminase/protease-like homologues
HKNIGPJH_00855 1.3e-50 lhr L DEAD DEAH box helicase
HKNIGPJH_00856 8.3e-102 lhr L DEAD DEAH box helicase
HKNIGPJH_00857 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HKNIGPJH_00858 1.3e-66 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HKNIGPJH_00859 1.3e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HKNIGPJH_00860 4.4e-103
HKNIGPJH_00861 4.5e-21 typA T Elongation factor G C-terminus
HKNIGPJH_00862 8.8e-177 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKNIGPJH_00863 2.6e-39 rpmA J Ribosomal L27 protein
HKNIGPJH_00864 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKNIGPJH_00865 8.5e-72 rne 3.1.26.12 J Ribonuclease E/G family
HKNIGPJH_00866 2.1e-285 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HKNIGPJH_00867 2.1e-137 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HKNIGPJH_00868 3.6e-85 ptpA 3.1.3.48 T low molecular weight
HKNIGPJH_00869 2.4e-129 folA 1.5.1.3 H dihydrofolate reductase
HKNIGPJH_00870 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKNIGPJH_00871 7.3e-206 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKNIGPJH_00872 2.8e-79 K helix_turn_helix ASNC type
HKNIGPJH_00873 5.3e-215 V FtsX-like permease family
HKNIGPJH_00874 1.9e-150 lolD V ABC transporter
HKNIGPJH_00875 6.1e-257 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKNIGPJH_00876 8.2e-63 I Sterol carrier protein
HKNIGPJH_00877 3.4e-141 glpR K DeoR C terminal sensor domain
HKNIGPJH_00878 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HKNIGPJH_00879 1.9e-89 S Vitamin K epoxide reductase
HKNIGPJH_00880 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HKNIGPJH_00881 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKNIGPJH_00882 4.8e-28 5.3.1.27 G SIS domain
HKNIGPJH_00883 0.0 V ABC transporter transmembrane region
HKNIGPJH_00885 5.4e-181 S Auxin Efflux Carrier
HKNIGPJH_00886 9.7e-52 pgi 5.3.1.9 G Belongs to the GPI family
HKNIGPJH_00887 3.6e-88 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKNIGPJH_00888 9e-72 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKNIGPJH_00889 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HKNIGPJH_00890 6.7e-18 guaB 1.1.1.205 F IMP dehydrogenase family protein
HKNIGPJH_00891 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HKNIGPJH_00892 1.2e-132 V Efflux ABC transporter, permease protein
HKNIGPJH_00893 4.5e-16
HKNIGPJH_00894 1.9e-121 recX S Modulates RecA activity
HKNIGPJH_00895 2.6e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKNIGPJH_00896 3.4e-55 DJ Addiction module toxin, RelE StbE family
HKNIGPJH_00897 1.3e-48 S Antitoxin component of a toxin-antitoxin (TA) module
HKNIGPJH_00898 1.7e-125 S Short repeat of unknown function (DUF308)
HKNIGPJH_00899 1.9e-17 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_00900 6.2e-103 S Domain of unknown function (DUF4037)
HKNIGPJH_00901 9.6e-35 S Domain of unknown function (DUF4037)
HKNIGPJH_00902 7e-37 araJ EGP Major facilitator Superfamily
HKNIGPJH_00903 1.7e-218 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKNIGPJH_00904 1.7e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNIGPJH_00905 1.1e-25 pflA S Protein of unknown function (DUF4012)
HKNIGPJH_00906 9.1e-25 pflA S Protein of unknown function (DUF4012)
HKNIGPJH_00907 5.2e-181 rhaR_1 K helix_turn_helix, arabinose operon control protein
HKNIGPJH_00908 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
HKNIGPJH_00909 1.9e-250 EGP Major facilitator Superfamily
HKNIGPJH_00910 1.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HKNIGPJH_00911 3.2e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNIGPJH_00912 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HKNIGPJH_00913 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
HKNIGPJH_00914 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKNIGPJH_00915 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HKNIGPJH_00916 3.4e-26
HKNIGPJH_00917 2.2e-246 G Bacterial extracellular solute-binding protein
HKNIGPJH_00918 2.1e-106 G Bacterial extracellular solute-binding protein
HKNIGPJH_00919 1.2e-42 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKNIGPJH_00920 2.3e-129 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HKNIGPJH_00921 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
HKNIGPJH_00922 5.1e-134 ybbM V Uncharacterised protein family (UPF0014)
HKNIGPJH_00923 9.2e-142 ybbL V ATPases associated with a variety of cellular activities
HKNIGPJH_00924 1.7e-218 GK ROK family
HKNIGPJH_00925 1.5e-43 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HKNIGPJH_00926 2.4e-62 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HKNIGPJH_00927 6.6e-224 2.7.13.3 T Histidine kinase
HKNIGPJH_00928 4.7e-67 K helix_turn_helix, Lux Regulon
HKNIGPJH_00929 8.6e-31 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HKNIGPJH_00930 4e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKNIGPJH_00931 4.7e-45 L Psort location Cytoplasmic, score 8.87
HKNIGPJH_00932 4.5e-50 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HKNIGPJH_00934 5.7e-172 corA P CorA-like Mg2+ transporter protein
HKNIGPJH_00935 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HKNIGPJH_00936 4.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNIGPJH_00937 1.5e-142 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKNIGPJH_00938 1.3e-227 rutG F Permease family
HKNIGPJH_00939 8.2e-45 S Nucleotidyltransferase domain
HKNIGPJH_00940 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HKNIGPJH_00941 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
HKNIGPJH_00942 3e-128 V ABC transporter
HKNIGPJH_00943 1.1e-62 V ABC transporter permease
HKNIGPJH_00944 4.6e-137 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKNIGPJH_00945 1.2e-112 I acetylesterase activity
HKNIGPJH_00946 5e-54 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HKNIGPJH_00947 3e-150 nrtR 3.6.1.55 F NUDIX hydrolase
HKNIGPJH_00948 3.2e-88 naiP U Sugar (and other) transporter
HKNIGPJH_00950 2.1e-253 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKNIGPJH_00951 3.4e-106 2.8.2.22 S Arylsulfotransferase Ig-like domain
HKNIGPJH_00952 5e-145 bioM P ATPases associated with a variety of cellular activities
HKNIGPJH_00953 1.8e-113 E Aminotransferase class I and II
HKNIGPJH_00954 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKNIGPJH_00955 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKNIGPJH_00956 5.4e-124 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKNIGPJH_00957 1.1e-59 P NMT1/THI5 like
HKNIGPJH_00958 2.8e-214 iunH1 3.2.2.1 F nucleoside hydrolase
HKNIGPJH_00959 4.1e-28 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKNIGPJH_00960 2.6e-09 G Transmembrane secretion effector
HKNIGPJH_00961 3.5e-120 K Bacterial regulatory proteins, tetR family
HKNIGPJH_00962 1.1e-39 nrdH O Glutaredoxin
HKNIGPJH_00963 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
HKNIGPJH_00964 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKNIGPJH_00965 2.7e-70 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKNIGPJH_00966 3.5e-103 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKNIGPJH_00967 1.3e-190 T Universal stress protein family
HKNIGPJH_00968 1.3e-79 M NlpC/P60 family
HKNIGPJH_00969 4.1e-86 3.1.3.48 T Low molecular weight phosphatase family
HKNIGPJH_00970 1.3e-182 S Endonuclease/Exonuclease/phosphatase family
HKNIGPJH_00971 1.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKNIGPJH_00972 3.4e-112 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKNIGPJH_00974 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HKNIGPJH_00975 1.7e-16 trxB1 1.8.1.9 C Thioredoxin domain
HKNIGPJH_00976 3.4e-48 trxB1 1.8.1.9 C Thioredoxin domain
HKNIGPJH_00977 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HKNIGPJH_00978 3.5e-244 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKNIGPJH_00979 4.8e-156 carA 6.3.5.5 F Belongs to the CarA family
HKNIGPJH_00980 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HKNIGPJH_00981 1.3e-210 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKNIGPJH_00982 5.7e-54 M Protein of unknown function (DUF3152)
HKNIGPJH_00983 1.3e-299 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HKNIGPJH_00984 2.2e-34 crr G pts system, glucose-specific IIABC component
HKNIGPJH_00985 9.2e-82
HKNIGPJH_00986 3.2e-79 2.7.11.1 NU Tfp pilus assembly protein FimV
HKNIGPJH_00987 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKNIGPJH_00988 2.7e-227 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKNIGPJH_00989 6e-100 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNIGPJH_00990 7.9e-20 T helix_turn_helix, Lux Regulon
HKNIGPJH_00991 1.6e-30 2.7.13.3 T Histidine kinase
HKNIGPJH_00992 1.6e-39 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKNIGPJH_00993 1.3e-99 yjjP S Threonine/Serine exporter, ThrE
HKNIGPJH_00994 6.1e-170 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKNIGPJH_00995 4.3e-21 atpB C it plays a direct role in the translocation of protons across the membrane
HKNIGPJH_00996 7.7e-22 atpB C it plays a direct role in the translocation of protons across the membrane
HKNIGPJH_00997 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HKNIGPJH_00998 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HKNIGPJH_00999 2.7e-229 P Sodium/hydrogen exchanger family
HKNIGPJH_01000 0.0 V FtsX-like permease family
HKNIGPJH_01001 5.4e-270 aroP E aromatic amino acid transport protein AroP K03293
HKNIGPJH_01002 8.3e-12 S Protein of unknown function, DUF624
HKNIGPJH_01003 2.5e-189 K helix_turn _helix lactose operon repressor
HKNIGPJH_01004 4.9e-39 G beta-mannosidase
HKNIGPJH_01005 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HKNIGPJH_01006 1.6e-60 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKNIGPJH_01007 5.2e-15
HKNIGPJH_01008 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
HKNIGPJH_01009 7.8e-174 V ATPases associated with a variety of cellular activities
HKNIGPJH_01010 1.1e-98 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKNIGPJH_01011 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HKNIGPJH_01012 9.2e-197 D FtsK/SpoIIIE family
HKNIGPJH_01013 9.5e-113 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKNIGPJH_01014 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HKNIGPJH_01015 9.2e-29 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKNIGPJH_01016 2.3e-19 V Beta-lactamase
HKNIGPJH_01017 9.3e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKNIGPJH_01018 2.1e-57 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
HKNIGPJH_01019 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKNIGPJH_01020 1.3e-67 cydD V ABC transporter transmembrane region
HKNIGPJH_01022 3.7e-265 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNIGPJH_01023 1.9e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HKNIGPJH_01024 2.8e-121
HKNIGPJH_01025 5.9e-77 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKNIGPJH_01026 2.3e-108 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKNIGPJH_01027 1.1e-181 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKNIGPJH_01028 9.2e-15 3.1.21.3 V DivIVA protein
HKNIGPJH_01029 6.9e-41 yggT S YGGT family
HKNIGPJH_01030 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKNIGPJH_01031 1e-31 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKNIGPJH_01032 1.7e-22 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HKNIGPJH_01033 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HKNIGPJH_01034 4e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKNIGPJH_01035 3.8e-84 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKNIGPJH_01036 7.9e-263 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HKNIGPJH_01037 4e-53 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01038 9.1e-30 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01039 0.0 yjjK S ATP-binding cassette protein, ChvD family
HKNIGPJH_01040 2e-33 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKNIGPJH_01041 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKNIGPJH_01042 1.6e-61 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKNIGPJH_01043 5.3e-40 GK ROK family
HKNIGPJH_01044 2.7e-198 lacS G Psort location CytoplasmicMembrane, score 10.00
HKNIGPJH_01045 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKNIGPJH_01046 5.5e-74 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKNIGPJH_01047 1.4e-18 argR K Regulates arginine biosynthesis genes
HKNIGPJH_01048 3.8e-55 argR K Regulates arginine biosynthesis genes
HKNIGPJH_01049 1.5e-126 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKNIGPJH_01050 1.6e-140 3.5.2.10 S Creatinine amidohydrolase
HKNIGPJH_01051 1.2e-169 proP EGP Sugar (and other) transporter
HKNIGPJH_01053 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKNIGPJH_01054 1.5e-65 msmF G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01055 1.7e-182 K Psort location Cytoplasmic, score
HKNIGPJH_01056 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKNIGPJH_01057 1e-37 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNIGPJH_01058 4.5e-172 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNIGPJH_01059 2.5e-42 S Protein of unknown function (DUF721)
HKNIGPJH_01060 4.3e-31 F Psort location CytoplasmicMembrane, score 10.00
HKNIGPJH_01061 3.4e-43 F Psort location CytoplasmicMembrane, score 10.00
HKNIGPJH_01062 5.4e-121 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HKNIGPJH_01063 2.8e-13 gluC E Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01064 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01065 7.3e-47 arc O AAA ATPase forming ring-shaped complexes
HKNIGPJH_01066 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HKNIGPJH_01067 1.2e-22 lacY P LacY proton/sugar symporter
HKNIGPJH_01068 5.1e-147 K helix_turn _helix lactose operon repressor
HKNIGPJH_01069 3.6e-140 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKNIGPJH_01070 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKNIGPJH_01071 4.5e-157 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HKNIGPJH_01072 5.5e-53 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNIGPJH_01073 7.3e-74 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNIGPJH_01074 8e-147
HKNIGPJH_01075 7.1e-186 sufB O FeS assembly protein SufB
HKNIGPJH_01076 5.1e-130 sufD O FeS assembly protein SufD
HKNIGPJH_01077 1.7e-194 pknL 2.7.11.1 KLT PASTA
HKNIGPJH_01078 1.2e-120 plsC2 2.3.1.51 I Phosphate acyltransferases
HKNIGPJH_01079 9.2e-124 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKNIGPJH_01080 3.6e-67 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKNIGPJH_01081 8.7e-58 macB_2 V ATPases associated with a variety of cellular activities
HKNIGPJH_01084 4e-195 XK27_01805 M Glycosyltransferase like family 2
HKNIGPJH_01085 7.8e-302 pepD E Peptidase family C69
HKNIGPJH_01088 6e-38 nrdH O Glutaredoxin
HKNIGPJH_01089 2e-225 S Putative ABC-transporter type IV
HKNIGPJH_01090 0.0 pip S YhgE Pip domain protein
HKNIGPJH_01091 2.6e-22 pip S YhgE Pip domain protein
HKNIGPJH_01092 1.5e-31 pip S YhgE Pip domain protein
HKNIGPJH_01093 1.7e-56 htpX O Belongs to the peptidase M48B family
HKNIGPJH_01094 6.5e-207 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HKNIGPJH_01095 4.1e-86 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNIGPJH_01096 6.4e-221 clcA P Voltage gated chloride channel
HKNIGPJH_01097 2e-129 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKNIGPJH_01098 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKNIGPJH_01099 4.3e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HKNIGPJH_01100 1.9e-37 murB 1.3.1.98 M Cell wall formation
HKNIGPJH_01101 4.8e-266 E aromatic amino acid transport protein AroP K03293
HKNIGPJH_01102 6e-123 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HKNIGPJH_01103 1.1e-74 S GtrA-like protein
HKNIGPJH_01104 3.7e-10 S LPXTG-motif cell wall anchor domain protein
HKNIGPJH_01105 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKNIGPJH_01106 8.8e-223 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HKNIGPJH_01107 1e-37 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKNIGPJH_01108 4e-94 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HKNIGPJH_01109 9e-70 htpX O Belongs to the peptidase M48B family
HKNIGPJH_01110 1.3e-124 KT MT-A70
HKNIGPJH_01111 5.2e-108 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HKNIGPJH_01112 9.8e-213 rhaR1 K helix_turn_helix, arabinose operon control protein
HKNIGPJH_01113 9e-110 znuC P ATPases associated with a variety of cellular activities
HKNIGPJH_01114 3.9e-140 znuB U ABC 3 transport family
HKNIGPJH_01115 6.1e-58 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKNIGPJH_01116 1.2e-235 S AI-2E family transporter
HKNIGPJH_01118 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKNIGPJH_01119 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKNIGPJH_01120 1.3e-47 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKNIGPJH_01121 1.9e-145 K helix_turn _helix lactose operon repressor
HKNIGPJH_01122 1.7e-161 3.2.1.97 GH101 G Glycosyl hydrolases family 43
HKNIGPJH_01123 9.6e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HKNIGPJH_01124 4.5e-98 metY 2.5.1.49 E Aminotransferase class-V
HKNIGPJH_01125 3.1e-124 S Phospholipase/Carboxylesterase
HKNIGPJH_01126 1.1e-124 patB 4.4.1.8 E Aminotransferase, class I II
HKNIGPJH_01127 1.4e-113 S Protein of unknown function DUF262
HKNIGPJH_01128 5.1e-243 T Histidine kinase
HKNIGPJH_01129 2.6e-40 V ABC-2 family transporter protein
HKNIGPJH_01130 1.7e-190 V ATPases associated with a variety of cellular activities
HKNIGPJH_01131 1.9e-56 T Histidine kinase
HKNIGPJH_01132 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKNIGPJH_01133 2.2e-113 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKNIGPJH_01134 1.8e-34 pbuX F Permease family
HKNIGPJH_01135 2.8e-301 yrhL I Psort location CytoplasmicMembrane, score 9.99
HKNIGPJH_01136 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HKNIGPJH_01137 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKNIGPJH_01138 9.4e-98 mntP P Probably functions as a manganese efflux pump
HKNIGPJH_01139 4.9e-134
HKNIGPJH_01140 4.9e-134 KT Transcriptional regulatory protein, C terminal
HKNIGPJH_01141 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKNIGPJH_01142 7.8e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKNIGPJH_01143 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNIGPJH_01144 4.3e-183 G Bacterial Ig-like domain (group 4)
HKNIGPJH_01145 6.5e-46 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNIGPJH_01146 3.9e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKNIGPJH_01147 1.6e-46 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKNIGPJH_01148 2e-115 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_01149 2e-13
HKNIGPJH_01152 4.2e-95 yvdD 3.2.2.10 S Possible lysine decarboxylase
HKNIGPJH_01153 1.3e-108 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKNIGPJH_01154 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKNIGPJH_01155 4e-131 ftsK D FtsK SpoIIIE family protein
HKNIGPJH_01156 1.2e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKNIGPJH_01157 8.5e-77 S LytR cell envelope-related transcriptional attenuator
HKNIGPJH_01158 1e-79 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKNIGPJH_01159 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HKNIGPJH_01160 8.9e-13 S zinc-ribbon domain
HKNIGPJH_01161 2.7e-116 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKNIGPJH_01162 2.2e-28 2.8.2.22 S Arylsulfotransferase Ig-like domain
HKNIGPJH_01163 1.8e-43 2.8.2.22 S Arylsulfotransferase Ig-like domain
HKNIGPJH_01165 2.3e-84 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKNIGPJH_01166 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HKNIGPJH_01167 1.3e-270 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_01168 4.8e-37 pepN 3.4.11.2 E Peptidase family M1 domain
HKNIGPJH_01169 5.4e-119 L DNA helicase
HKNIGPJH_01170 8.8e-150 L DNA helicase
HKNIGPJH_01171 1.4e-48
HKNIGPJH_01172 6.1e-252 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HKNIGPJH_01173 1.9e-26 P Bacterial extracellular solute-binding protein
HKNIGPJH_01174 3.1e-97 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKNIGPJH_01175 5.6e-124 livF E ATPases associated with a variety of cellular activities
HKNIGPJH_01176 2.4e-68 livG E ABC transporter
HKNIGPJH_01177 4.6e-91 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HKNIGPJH_01178 1.9e-203 G Major Facilitator Superfamily
HKNIGPJH_01179 9.8e-25 helY L DEAD DEAH box helicase
HKNIGPJH_01180 3.5e-79 helY L DEAD DEAH box helicase
HKNIGPJH_01181 1e-31 helY L DEAD DEAH box helicase
HKNIGPJH_01182 3.3e-49 D nuclear chromosome segregation
HKNIGPJH_01183 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKNIGPJH_01184 1.6e-149 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKNIGPJH_01185 1.4e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HKNIGPJH_01186 2.7e-296 yegQ O Peptidase family U32 C-terminal domain
HKNIGPJH_01187 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HKNIGPJH_01188 0.0 S Predicted membrane protein (DUF2207)
HKNIGPJH_01189 1.7e-91 lemA S LemA family
HKNIGPJH_01190 1.3e-09 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKNIGPJH_01191 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HKNIGPJH_01192 8.2e-145 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKNIGPJH_01193 1.1e-17 argE E Peptidase dimerisation domain
HKNIGPJH_01194 3.6e-93 S Protein of unknown function (DUF3043)
HKNIGPJH_01195 8e-53 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKNIGPJH_01196 6.6e-145 G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01197 4.5e-91 G PFAM binding-protein-dependent transport systems inner membrane component
HKNIGPJH_01198 1.6e-163 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKNIGPJH_01199 1.6e-96 metI P Psort location CytoplasmicMembrane, score 9.99
HKNIGPJH_01200 1.5e-149 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HKNIGPJH_01201 1.4e-240 trkB P Cation transport protein
HKNIGPJH_01203 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HKNIGPJH_01204 7e-77 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HKNIGPJH_01205 1.1e-264 E ABC transporter, substrate-binding protein, family 5
HKNIGPJH_01206 5.8e-111 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HKNIGPJH_01207 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01208 1.4e-18 E ABC transporter, substrate-binding protein, family 5
HKNIGPJH_01209 8.8e-139 cstA T 5TM C-terminal transporter carbon starvation CstA
HKNIGPJH_01210 6.2e-40 ybdD S Selenoprotein, putative
HKNIGPJH_01211 1.2e-86 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HKNIGPJH_01212 3.6e-70 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKNIGPJH_01213 3.4e-129 KT Transcriptional regulatory protein, C terminal
HKNIGPJH_01214 3e-196 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HKNIGPJH_01215 1.3e-163 pstC P probably responsible for the translocation of the substrate across the membrane
HKNIGPJH_01216 3.1e-168 pstA P Phosphate transport system permease
HKNIGPJH_01217 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNIGPJH_01218 3.1e-143 P Zinc-uptake complex component A periplasmic
HKNIGPJH_01219 1.1e-237 pbuO S Permease family
HKNIGPJH_01220 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKNIGPJH_01221 1.2e-97 I Diacylglycerol kinase catalytic domain
HKNIGPJH_01222 2.8e-157 arbG K CAT RNA binding domain
HKNIGPJH_01223 4.4e-36 crr G pts system, glucose-specific IIABC component
HKNIGPJH_01224 4.5e-163 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HKNIGPJH_01225 2e-104 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HKNIGPJH_01226 3.4e-163 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKNIGPJH_01229 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKNIGPJH_01230 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKNIGPJH_01231 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKNIGPJH_01232 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKNIGPJH_01233 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKNIGPJH_01234 9.9e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKNIGPJH_01235 9.8e-74 rplO J binds to the 23S rRNA
HKNIGPJH_01236 3.4e-25 rpmD J Ribosomal protein L30p/L7e
HKNIGPJH_01237 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKNIGPJH_01238 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKNIGPJH_01239 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKNIGPJH_01240 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKNIGPJH_01241 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKNIGPJH_01242 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKNIGPJH_01243 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKNIGPJH_01244 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKNIGPJH_01245 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKNIGPJH_01246 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HKNIGPJH_01247 1.6e-44 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKNIGPJH_01248 2.8e-51 L Restriction endonuclease BglII
HKNIGPJH_01249 1.1e-61
HKNIGPJH_01250 7.1e-27 D FtsK/SpoIIIE family
HKNIGPJH_01255 2.5e-25 L Phage integrase family
HKNIGPJH_01256 1.4e-59 L Phage integrase family
HKNIGPJH_01258 3.8e-187 K Helix-turn-helix XRE-family like proteins
HKNIGPJH_01259 1.8e-170 yddG EG EamA-like transporter family
HKNIGPJH_01260 1.8e-113 pip S YhgE Pip domain protein
HKNIGPJH_01261 2e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKNIGPJH_01262 9e-26 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HKNIGPJH_01263 7.2e-189 K Bacterial regulatory proteins, lacI family
HKNIGPJH_01264 2.6e-208 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HKNIGPJH_01265 2.7e-213 S Histidine phosphatase superfamily (branch 2)
HKNIGPJH_01266 3.1e-228 yliE T Putative diguanylate phosphodiesterase
HKNIGPJH_01267 5.1e-158 G Fructosamine kinase
HKNIGPJH_01268 2.5e-88 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKNIGPJH_01269 4.8e-82 T Response regulator receiver domain protein
HKNIGPJH_01270 1.6e-229 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKNIGPJH_01271 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKNIGPJH_01272 6.9e-168 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKNIGPJH_01273 9.4e-101 pdtaR T Response regulator receiver domain protein
HKNIGPJH_01274 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HKNIGPJH_01275 5.2e-08
HKNIGPJH_01276 2.8e-34
HKNIGPJH_01277 9.3e-89 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKNIGPJH_01278 9.3e-57 3.4.23.43 S Type IV leader peptidase family
HKNIGPJH_01279 4.3e-89 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKNIGPJH_01280 1.1e-81 hisA 3.5.4.19, 3.6.1.31, 5.3.1.16, 5.3.1.24 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKNIGPJH_01281 8.7e-175 M LPXTG-motif cell wall anchor domain protein
HKNIGPJH_01282 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
HKNIGPJH_01283 3.3e-192 yfdV S Membrane transport protein
HKNIGPJH_01284 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HKNIGPJH_01285 4.1e-82 L Phage integrase family
HKNIGPJH_01286 1.4e-70 3.2.1.20, 3.5.1.28 GH31 V N-acetylmuramoyl-L-alanine amidase
HKNIGPJH_01287 1.3e-187 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HKNIGPJH_01288 9.6e-208 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HKNIGPJH_01289 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HKNIGPJH_01290 1.7e-227 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKNIGPJH_01291 8.6e-142 S Domain of unknown function (DUF4191)
HKNIGPJH_01292 1.8e-99 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKNIGPJH_01293 1.8e-181 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HKNIGPJH_01294 2.1e-128 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKNIGPJH_01295 1.2e-65 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKNIGPJH_01296 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HKNIGPJH_01297 1.6e-162 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_01298 8.2e-104 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_01299 1.4e-37 S G5
HKNIGPJH_01300 1.8e-31 S G5
HKNIGPJH_01302 5e-27 O Thioredoxin
HKNIGPJH_01303 8.8e-109 J Acetyltransferase (GNAT) domain
HKNIGPJH_01304 8.8e-46 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKNIGPJH_01305 1.1e-95 bcp 1.11.1.15 O Redoxin
HKNIGPJH_01306 1.8e-29 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_01307 1.1e-256 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKNIGPJH_01308 1.8e-240 EGP Major facilitator Superfamily
HKNIGPJH_01309 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNIGPJH_01310 2e-269 KLT Domain of unknown function (DUF4032)
HKNIGPJH_01311 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
HKNIGPJH_01312 2.8e-131 K LytTr DNA-binding domain
HKNIGPJH_01313 2.7e-234 T GHKL domain
HKNIGPJH_01314 1.1e-30
HKNIGPJH_01316 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKNIGPJH_01317 4.9e-63
HKNIGPJH_01319 7.5e-101 XK27_00240 K Fic/DOC family
HKNIGPJH_01321 1.3e-166 T Pfam Adenylate and Guanylate cyclase catalytic domain
HKNIGPJH_01322 1.4e-289 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKNIGPJH_01323 1.7e-70 rplI J Binds to the 23S rRNA
HKNIGPJH_01324 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKNIGPJH_01325 9.7e-70 ssb1 L Single-stranded DNA-binding protein
HKNIGPJH_01326 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HKNIGPJH_01327 1.6e-185 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNIGPJH_01328 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKNIGPJH_01329 6.7e-179 EGP Major Facilitator Superfamily
HKNIGPJH_01330 8.9e-248 M domain protein
HKNIGPJH_01331 9e-209 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKNIGPJH_01332 3.1e-68 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNIGPJH_01333 3.7e-182 adh3 C Zinc-binding dehydrogenase
HKNIGPJH_01334 1.4e-148 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKNIGPJH_01335 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKNIGPJH_01336 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKNIGPJH_01337 6.8e-133 KT Response regulator receiver domain protein
HKNIGPJH_01338 1.3e-27
HKNIGPJH_01339 5.5e-53 azlD E Branched-chain amino acid transport protein (AzlD)
HKNIGPJH_01340 2.8e-42 azlC E AzlC protein
HKNIGPJH_01341 8.3e-50 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKNIGPJH_01342 2.6e-114 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HKNIGPJH_01343 1.1e-38 csoR S Metal-sensitive transcriptional repressor
HKNIGPJH_01344 1.9e-77 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKNIGPJH_01345 4.4e-50 cysB 4.2.1.22 EGP Major facilitator Superfamily
HKNIGPJH_01346 4.5e-26 cysB 4.2.1.22 EGP Major facilitator Superfamily
HKNIGPJH_01347 7.9e-43 cysB 4.2.1.22 EGP Major facilitator Superfamily
HKNIGPJH_01348 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
HKNIGPJH_01349 1.3e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKNIGPJH_01350 2.1e-114 lipA I Hydrolase, alpha beta domain protein
HKNIGPJH_01351 5e-27 S Psort location Cytoplasmic, score 8.87
HKNIGPJH_01352 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKNIGPJH_01353 4.6e-120 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKNIGPJH_01355 3.6e-117 2.7.11.1 NU Tfp pilus assembly protein FimV
HKNIGPJH_01356 6.4e-104 G Bacterial Ig-like domain (group 4)
HKNIGPJH_01357 8.7e-40 G Bacterial Ig-like domain (group 4)
HKNIGPJH_01358 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
HKNIGPJH_01359 2.2e-125 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HKNIGPJH_01360 1.3e-229 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKNIGPJH_01361 3.2e-24 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HKNIGPJH_01362 5.6e-129 pgm3 G Phosphoglycerate mutase family
HKNIGPJH_01363 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HKNIGPJH_01364 9e-184 lacR K Transcriptional regulator, LacI family
HKNIGPJH_01365 6.5e-31 bioY S BioY family
HKNIGPJH_01366 1.8e-187 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HKNIGPJH_01367 8e-64 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKNIGPJH_01368 5.7e-85 K Cro/C1-type HTH DNA-binding domain
HKNIGPJH_01369 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNIGPJH_01370 4.8e-93 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNIGPJH_01371 4.2e-264 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKNIGPJH_01373 1.3e-199 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKNIGPJH_01374 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
HKNIGPJH_01375 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKNIGPJH_01376 3.6e-41 pflB 2.3.1.54 C Pyruvate formate lyase-like
HKNIGPJH_01377 2e-90 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HKNIGPJH_01378 4.1e-112 S domain protein
HKNIGPJH_01379 1e-221 S Zincin-like metallopeptidase
HKNIGPJH_01380 9.6e-225 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKNIGPJH_01381 1.1e-11 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKNIGPJH_01382 8.5e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKNIGPJH_01383 1.4e-150 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKNIGPJH_01384 7.7e-169 rnd 3.1.13.5 J 3'-5' exonuclease
HKNIGPJH_01385 2.2e-159 pgi 5.3.1.9 G Belongs to the GPI family
HKNIGPJH_01386 4.4e-123 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HKNIGPJH_01387 4e-190 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKNIGPJH_01388 5.2e-46 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNIGPJH_01389 1.5e-169 cotH M CotH kinase protein
HKNIGPJH_01390 1.3e-143 S Sulfite exporter TauE/SafE
HKNIGPJH_01391 3.9e-93 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_01392 1.8e-56 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKNIGPJH_01393 3.2e-101
HKNIGPJH_01394 1e-60 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKNIGPJH_01395 1.2e-186 G Major Facilitator Superfamily
HKNIGPJH_01396 2.2e-128 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKNIGPJH_01397 1.5e-139 dppB EP Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01398 3.2e-92 V ABC-2 family transporter protein
HKNIGPJH_01399 2.8e-143 V ABC-2 family transporter protein
HKNIGPJH_01400 3.3e-40 G Transporter major facilitator family protein
HKNIGPJH_01401 3.8e-10 bioY S BioY family
HKNIGPJH_01402 3.9e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HKNIGPJH_01403 3.5e-35
HKNIGPJH_01404 1.8e-61 yebC K transcriptional regulatory protein
HKNIGPJH_01405 5.1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKNIGPJH_01406 1.1e-203 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKNIGPJH_01407 5.2e-75 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKNIGPJH_01408 9.1e-14 S Psort location Extracellular, score 8.82
HKNIGPJH_01409 2.8e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKNIGPJH_01410 1.5e-84 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HKNIGPJH_01411 1.7e-41 XAC3035 O Glutaredoxin
HKNIGPJH_01412 2.7e-20 P Belongs to the ABC transporter superfamily
HKNIGPJH_01413 1.7e-73 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HKNIGPJH_01414 1.4e-142 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKNIGPJH_01415 1e-27 hom 1.1.1.3 E Homoserine dehydrogenase
HKNIGPJH_01416 4.2e-186 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKNIGPJH_01417 1.9e-219 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HKNIGPJH_01418 1.3e-171 whiA K May be required for sporulation
HKNIGPJH_01419 2.6e-17 yxiO S Vacuole effluxer Atg22 like
HKNIGPJH_01420 6.1e-39 yxiO S Vacuole effluxer Atg22 like
HKNIGPJH_01421 6.5e-41 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKNIGPJH_01422 8.2e-34
HKNIGPJH_01423 3e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKNIGPJH_01424 3.5e-103 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HKNIGPJH_01425 5.3e-192 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKNIGPJH_01426 2.1e-188 yegU O ADP-ribosylglycohydrolase
HKNIGPJH_01427 8.3e-190 yegV G pfkB family carbohydrate kinase
HKNIGPJH_01428 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
HKNIGPJH_01429 1.5e-103 Q Isochorismatase family
HKNIGPJH_01430 2.3e-214 S Choline/ethanolamine kinase
HKNIGPJH_01431 5.6e-275 eat E Amino acid permease
HKNIGPJH_01432 1.2e-108 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
HKNIGPJH_01433 1.7e-108 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HKNIGPJH_01434 2.6e-115 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKNIGPJH_01435 3.2e-56 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKNIGPJH_01436 9e-18
HKNIGPJH_01437 3e-54 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HKNIGPJH_01438 3.6e-28 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HKNIGPJH_01439 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HKNIGPJH_01440 1.3e-34 aspT EK Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKNIGPJH_01441 1.4e-82 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKNIGPJH_01442 1.2e-83 P Cobalt transport protein
HKNIGPJH_01443 2.6e-80 terC P Integral membrane protein, TerC family
HKNIGPJH_01444 4.8e-128 pyk 2.7.1.40 G Pyruvate kinase
HKNIGPJH_01445 2.5e-115 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HKNIGPJH_01446 1.7e-134 lysX S Uncharacterised conserved protein (DUF2156)
HKNIGPJH_01447 3e-167 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKNIGPJH_01448 3.1e-33 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNIGPJH_01449 3.3e-33 K helix_turn_helix, Lux Regulon
HKNIGPJH_01450 8.2e-160 T Histidine kinase
HKNIGPJH_01451 9.9e-55
HKNIGPJH_01452 1.4e-35 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKNIGPJH_01453 3.6e-201 K Cell envelope-related transcriptional attenuator domain
HKNIGPJH_01454 1.4e-66 macB_2 V ATPases associated with a variety of cellular activities
HKNIGPJH_01455 8.3e-35 macB_2 V ATPases associated with a variety of cellular activities
HKNIGPJH_01456 3.7e-23 M Protein of unknown function (DUF3737)
HKNIGPJH_01457 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKNIGPJH_01458 2.1e-66 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKNIGPJH_01459 1.4e-153 E ABC transporter, substrate-binding protein, family 5
HKNIGPJH_01460 1.4e-47 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKNIGPJH_01461 5.4e-35 S Transmembrane domain of unknown function (DUF3566)
HKNIGPJH_01462 4.4e-88 zur P Belongs to the Fur family
HKNIGPJH_01463 3.1e-80 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKNIGPJH_01464 2.8e-140 rmuC S RmuC family
HKNIGPJH_01465 1e-154 lon T Belongs to the peptidase S16 family
HKNIGPJH_01466 4.7e-96 G Bacterial extracellular solute-binding protein
HKNIGPJH_01467 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKNIGPJH_01468 3e-46 S Protein of unknown function (DUF3046)
HKNIGPJH_01469 6.1e-80 K Helix-turn-helix XRE-family like proteins
HKNIGPJH_01470 7.4e-76 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HKNIGPJH_01471 4.5e-92 dppC EP N-terminal TM domain of oligopeptide transport permease C
HKNIGPJH_01472 4.8e-230 malF G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01473 1e-162 malG G Binding-protein-dependent transport system inner membrane component
HKNIGPJH_01474 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HKNIGPJH_01475 5.4e-144 S HAD-hyrolase-like
HKNIGPJH_01476 2e-141 traX S TraX protein
HKNIGPJH_01477 1.3e-193 K Psort location Cytoplasmic, score
HKNIGPJH_01478 7.6e-174 pelF GT4 M Domain of unknown function (DUF3492)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)