ORF_ID e_value Gene_name EC_number CAZy COGs Description
DNEJFCKL_00001 2.7e-17 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00002 1.4e-189 K Periplasmic binding protein domain
DNEJFCKL_00003 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DNEJFCKL_00004 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DNEJFCKL_00005 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DNEJFCKL_00006 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
DNEJFCKL_00007 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00008 9.2e-151 pknD ET ABC transporter, substrate-binding protein, family 3
DNEJFCKL_00009 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
DNEJFCKL_00010 1.1e-156 pknD ET ABC transporter, substrate-binding protein, family 3
DNEJFCKL_00011 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DNEJFCKL_00012 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
DNEJFCKL_00013 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DNEJFCKL_00014 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
DNEJFCKL_00015 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DNEJFCKL_00016 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DNEJFCKL_00017 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DNEJFCKL_00018 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DNEJFCKL_00019 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
DNEJFCKL_00020 0.0 pepO 3.4.24.71 O Peptidase family M13
DNEJFCKL_00021 1.4e-98 L Single-strand binding protein family
DNEJFCKL_00022 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DNEJFCKL_00023 3e-270 recD2 3.6.4.12 L PIF1-like helicase
DNEJFCKL_00024 8.8e-159 supH S Sucrose-6F-phosphate phosphohydrolase
DNEJFCKL_00025 2.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DNEJFCKL_00026 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DNEJFCKL_00027 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DNEJFCKL_00028 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
DNEJFCKL_00029 1.9e-124 livF E ATPases associated with a variety of cellular activities
DNEJFCKL_00030 2.4e-150 E Branched-chain amino acid ATP-binding cassette transporter
DNEJFCKL_00031 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
DNEJFCKL_00032 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
DNEJFCKL_00033 7.8e-219 livK E Receptor family ligand binding region
DNEJFCKL_00034 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DNEJFCKL_00035 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DNEJFCKL_00036 1.5e-35 rpmE J Binds the 23S rRNA
DNEJFCKL_00038 6.8e-226 xylR GK ROK family
DNEJFCKL_00039 1.9e-286 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DNEJFCKL_00040 3.6e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DNEJFCKL_00041 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DNEJFCKL_00042 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DNEJFCKL_00043 6e-42 MA20_14020 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00044 6.2e-111 MA20_14020 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00045 1.5e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00046 2.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
DNEJFCKL_00047 7.2e-189 K Bacterial regulatory proteins, lacI family
DNEJFCKL_00048 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
DNEJFCKL_00049 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DNEJFCKL_00050 4.9e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
DNEJFCKL_00051 2.9e-295 S Amidohydrolase family
DNEJFCKL_00052 4.2e-77 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DNEJFCKL_00054 2.1e-174 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
DNEJFCKL_00055 9.3e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DNEJFCKL_00056 5.9e-182 V Beta-lactamase
DNEJFCKL_00057 0.0 yjjK S ATP-binding cassette protein, ChvD family
DNEJFCKL_00058 1.1e-164 tesB I Thioesterase-like superfamily
DNEJFCKL_00059 6.2e-94 S Protein of unknown function (DUF3180)
DNEJFCKL_00060 9.8e-275 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DNEJFCKL_00061 6.9e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DNEJFCKL_00062 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DNEJFCKL_00063 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DNEJFCKL_00064 8.6e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DNEJFCKL_00065 1.5e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DNEJFCKL_00066 2e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DNEJFCKL_00067 6.3e-232 epsG M Glycosyl transferase family 21
DNEJFCKL_00068 1.3e-237 S AI-2E family transporter
DNEJFCKL_00069 4.2e-180 3.4.14.13 M Glycosyltransferase like family 2
DNEJFCKL_00070 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DNEJFCKL_00071 0.0 yliE T Putative diguanylate phosphodiesterase
DNEJFCKL_00072 2.5e-110 S Domain of unknown function (DUF4956)
DNEJFCKL_00073 2.2e-159 P VTC domain
DNEJFCKL_00074 0.0 cotH M CotH kinase protein
DNEJFCKL_00075 3.5e-280 pelG S Putative exopolysaccharide Exporter (EPS-E)
DNEJFCKL_00076 2.6e-277 pelF GT4 M Domain of unknown function (DUF3492)
DNEJFCKL_00077 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
DNEJFCKL_00078 2e-161
DNEJFCKL_00079 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
DNEJFCKL_00083 1.1e-169 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DNEJFCKL_00084 9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DNEJFCKL_00086 3.6e-85 ptpA 3.1.3.48 T low molecular weight
DNEJFCKL_00087 3.2e-129 folA 1.5.1.3 H dihydrofolate reductase
DNEJFCKL_00088 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DNEJFCKL_00089 7.7e-73 attW O OsmC-like protein
DNEJFCKL_00090 1.3e-190 T Universal stress protein family
DNEJFCKL_00091 6.5e-79 M NlpC/P60 family
DNEJFCKL_00092 1.3e-165 usp 3.5.1.28 CBM50 S CHAP domain
DNEJFCKL_00093 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DNEJFCKL_00094 6.2e-41
DNEJFCKL_00095 9.6e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DNEJFCKL_00096 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
DNEJFCKL_00097 0.0 4.2.1.53 S MCRA family
DNEJFCKL_00098 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DNEJFCKL_00099 1.3e-196 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DNEJFCKL_00100 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DNEJFCKL_00102 2.4e-212 araJ EGP Major facilitator Superfamily
DNEJFCKL_00103 0.0 S Domain of unknown function (DUF4037)
DNEJFCKL_00104 2.3e-116 S Protein of unknown function (DUF4125)
DNEJFCKL_00105 2.7e-92
DNEJFCKL_00106 4.1e-145 pspC KT PspC domain
DNEJFCKL_00107 1.3e-264 tcsS3 KT PspC domain
DNEJFCKL_00108 5.6e-121 degU K helix_turn_helix, Lux Regulon
DNEJFCKL_00109 7.4e-103 Q Isochorismatase family
DNEJFCKL_00110 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
DNEJFCKL_00111 8.3e-190 yegV G pfkB family carbohydrate kinase
DNEJFCKL_00112 2.3e-187 yegU O ADP-ribosylglycohydrolase
DNEJFCKL_00114 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DNEJFCKL_00115 8.3e-199 I Diacylglycerol kinase catalytic domain
DNEJFCKL_00116 4e-156 arbG K CAT RNA binding domain
DNEJFCKL_00117 0.0 crr G pts system, glucose-specific IIABC component
DNEJFCKL_00118 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DNEJFCKL_00119 2.1e-151 T LytTr DNA-binding domain
DNEJFCKL_00120 5.7e-250 T GHKL domain
DNEJFCKL_00121 2.5e-212 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNEJFCKL_00122 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DNEJFCKL_00124 3.8e-108
DNEJFCKL_00125 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DNEJFCKL_00126 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DNEJFCKL_00127 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DNEJFCKL_00128 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DNEJFCKL_00129 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DNEJFCKL_00130 6.1e-191 nusA K Participates in both transcription termination and antitermination
DNEJFCKL_00131 4.4e-102
DNEJFCKL_00133 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DNEJFCKL_00134 1.3e-66 rplQ J Ribosomal protein L17
DNEJFCKL_00135 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DNEJFCKL_00136 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DNEJFCKL_00137 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DNEJFCKL_00138 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DNEJFCKL_00139 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DNEJFCKL_00140 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DNEJFCKL_00141 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DNEJFCKL_00142 9.8e-74 rplO J binds to the 23S rRNA
DNEJFCKL_00143 3.4e-25 rpmD J Ribosomal protein L30p/L7e
DNEJFCKL_00144 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DNEJFCKL_00145 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DNEJFCKL_00146 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DNEJFCKL_00147 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DNEJFCKL_00148 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DNEJFCKL_00149 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DNEJFCKL_00150 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DNEJFCKL_00151 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DNEJFCKL_00152 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DNEJFCKL_00153 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
DNEJFCKL_00154 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DNEJFCKL_00155 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DNEJFCKL_00156 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DNEJFCKL_00157 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DNEJFCKL_00158 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DNEJFCKL_00159 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DNEJFCKL_00160 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
DNEJFCKL_00161 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DNEJFCKL_00162 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
DNEJFCKL_00163 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DNEJFCKL_00164 5.2e-181 rhaR_1 K helix_turn_helix, arabinose operon control protein
DNEJFCKL_00165 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
DNEJFCKL_00166 4.2e-239 EGP Major facilitator Superfamily
DNEJFCKL_00167 1.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DNEJFCKL_00168 3.2e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DNEJFCKL_00169 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DNEJFCKL_00170 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
DNEJFCKL_00171 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DNEJFCKL_00172 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DNEJFCKL_00173 3.1e-122
DNEJFCKL_00174 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DNEJFCKL_00175 2.7e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DNEJFCKL_00176 7.2e-253 M Bacterial capsule synthesis protein PGA_cap
DNEJFCKL_00177 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DNEJFCKL_00179 3.6e-295 CE10 I Belongs to the type-B carboxylesterase lipase family
DNEJFCKL_00180 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
DNEJFCKL_00181 4.1e-233 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
DNEJFCKL_00182 0.0 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_00183 1e-36 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DNEJFCKL_00184 1.9e-214 dapC E Aminotransferase class I and II
DNEJFCKL_00185 8.3e-59 fdxA C 4Fe-4S binding domain
DNEJFCKL_00186 1.3e-266 E aromatic amino acid transport protein AroP K03293
DNEJFCKL_00187 1.9e-204 murB 1.3.1.98 M Cell wall formation
DNEJFCKL_00188 5.5e-25 rpmG J Ribosomal protein L33
DNEJFCKL_00192 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DNEJFCKL_00193 1.6e-147
DNEJFCKL_00194 1.7e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DNEJFCKL_00195 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DNEJFCKL_00196 6.1e-30 fmdB S Putative regulatory protein
DNEJFCKL_00197 1.9e-92 flgA NO SAF
DNEJFCKL_00198 4.8e-36
DNEJFCKL_00199 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DNEJFCKL_00200 3.9e-177 T Forkhead associated domain
DNEJFCKL_00201 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DNEJFCKL_00202 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DNEJFCKL_00203 8.7e-246 pbuO S Permease family
DNEJFCKL_00204 9.5e-145 P Zinc-uptake complex component A periplasmic
DNEJFCKL_00205 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DNEJFCKL_00206 4e-168 pstA P Phosphate transport system permease
DNEJFCKL_00207 1.7e-163 pstC P probably responsible for the translocation of the substrate across the membrane
DNEJFCKL_00208 6.1e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DNEJFCKL_00209 3.4e-129 KT Transcriptional regulatory protein, C terminal
DNEJFCKL_00210 3.1e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DNEJFCKL_00211 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DNEJFCKL_00212 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DNEJFCKL_00213 3.3e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DNEJFCKL_00214 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
DNEJFCKL_00215 1.3e-58 D nuclear chromosome segregation
DNEJFCKL_00216 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DNEJFCKL_00217 4.6e-143 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DNEJFCKL_00218 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DNEJFCKL_00219 2.7e-296 yegQ O Peptidase family U32 C-terminal domain
DNEJFCKL_00220 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DNEJFCKL_00221 0.0 S Predicted membrane protein (DUF2207)
DNEJFCKL_00222 1.7e-91 lemA S LemA family
DNEJFCKL_00223 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DNEJFCKL_00224 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DNEJFCKL_00225 2.4e-116
DNEJFCKL_00227 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
DNEJFCKL_00228 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DNEJFCKL_00229 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
DNEJFCKL_00230 0.0 pccB I Carboxyl transferase domain
DNEJFCKL_00231 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DNEJFCKL_00232 2.1e-79 bioY S BioY family
DNEJFCKL_00233 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DNEJFCKL_00234 0.0
DNEJFCKL_00235 5.9e-143 QT PucR C-terminal helix-turn-helix domain
DNEJFCKL_00236 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DNEJFCKL_00237 3.3e-95 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DNEJFCKL_00238 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
DNEJFCKL_00239 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DNEJFCKL_00241 3.7e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DNEJFCKL_00242 6.7e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DNEJFCKL_00243 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DNEJFCKL_00244 2.6e-39 rpmA J Ribosomal L27 protein
DNEJFCKL_00245 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DNEJFCKL_00246 1.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
DNEJFCKL_00247 1.8e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
DNEJFCKL_00248 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DNEJFCKL_00249 2.5e-270 V Efflux ABC transporter, permease protein
DNEJFCKL_00250 5e-128 V ATPases associated with a variety of cellular activities
DNEJFCKL_00251 6.1e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DNEJFCKL_00252 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DNEJFCKL_00253 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DNEJFCKL_00254 2.4e-121 pgi 5.3.1.9 G Belongs to the GPI family
DNEJFCKL_00255 1.4e-18 E ABC transporter, substrate-binding protein, family 5
DNEJFCKL_00256 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00257 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
DNEJFCKL_00258 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
DNEJFCKL_00259 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DNEJFCKL_00260 1.7e-151 S Protein of unknown function (DUF3710)
DNEJFCKL_00261 2.4e-133 S Protein of unknown function (DUF3159)
DNEJFCKL_00262 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DNEJFCKL_00263 1.5e-98
DNEJFCKL_00264 0.0 ctpE P E1-E2 ATPase
DNEJFCKL_00265 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DNEJFCKL_00266 4.9e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
DNEJFCKL_00267 5.2e-108 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DNEJFCKL_00268 2.2e-209 rhaR1 K helix_turn_helix, arabinose operon control protein
DNEJFCKL_00269 8.9e-229 V ABC-2 family transporter protein
DNEJFCKL_00270 7.7e-225 V ABC-2 family transporter protein
DNEJFCKL_00271 1.7e-190 V ATPases associated with a variety of cellular activities
DNEJFCKL_00272 3.2e-245 T Histidine kinase
DNEJFCKL_00273 9e-116 K helix_turn_helix, Lux Regulon
DNEJFCKL_00274 0.0 S Protein of unknown function DUF262
DNEJFCKL_00275 1.8e-127 K helix_turn_helix, Lux Regulon
DNEJFCKL_00276 5.1e-243 T Histidine kinase
DNEJFCKL_00277 6.7e-60 S Domain of unknown function (DUF5067)
DNEJFCKL_00278 8.6e-116 ybhL S Belongs to the BI1 family
DNEJFCKL_00279 6.2e-177 ydeD EG EamA-like transporter family
DNEJFCKL_00280 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DNEJFCKL_00281 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DNEJFCKL_00282 1.3e-193 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DNEJFCKL_00283 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DNEJFCKL_00284 0.0 ftsK D FtsK SpoIIIE family protein
DNEJFCKL_00285 4.1e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DNEJFCKL_00286 6.1e-97 cinA 3.5.1.42 S Belongs to the CinA family
DNEJFCKL_00287 1.6e-80 K Helix-turn-helix XRE-family like proteins
DNEJFCKL_00288 4.3e-46 S Protein of unknown function (DUF3046)
DNEJFCKL_00289 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DNEJFCKL_00290 1.3e-122 recX S Modulates RecA activity
DNEJFCKL_00291 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DNEJFCKL_00292 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DNEJFCKL_00293 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DNEJFCKL_00294 1.3e-97
DNEJFCKL_00295 1.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
DNEJFCKL_00296 0.0 pknL 2.7.11.1 KLT PASTA
DNEJFCKL_00297 5.9e-197 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DNEJFCKL_00298 2.5e-118
DNEJFCKL_00299 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DNEJFCKL_00300 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DNEJFCKL_00301 1.5e-222 G Major Facilitator Superfamily
DNEJFCKL_00302 5.6e-242 T PhoQ Sensor
DNEJFCKL_00303 2.4e-79 S Protein of unknown function (DUF2975)
DNEJFCKL_00304 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
DNEJFCKL_00305 0.0 lhr L DEAD DEAH box helicase
DNEJFCKL_00306 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DNEJFCKL_00307 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
DNEJFCKL_00308 4.1e-147 S Protein of unknown function (DUF3071)
DNEJFCKL_00309 1e-47 S Domain of unknown function (DUF4193)
DNEJFCKL_00310 8.5e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DNEJFCKL_00311 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DNEJFCKL_00312 3.5e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DNEJFCKL_00313 2.1e-244 dinF V MatE
DNEJFCKL_00314 3.4e-162 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_00315 2.5e-272 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_00316 5.9e-120 L Phage integrase, N-terminal SAM-like domain
DNEJFCKL_00317 1.9e-10
DNEJFCKL_00318 2.1e-101
DNEJFCKL_00323 1.7e-52 V Type II restriction enzyme, methylase subunits
DNEJFCKL_00324 7.8e-204 V Type II restriction enzyme, methylase subunits
DNEJFCKL_00326 3.3e-28 S Bacterial mobilisation protein (MobC)
DNEJFCKL_00327 1.1e-150 ltrBE1 U Relaxase/Mobilisation nuclease domain
DNEJFCKL_00328 7.1e-16
DNEJFCKL_00329 5.2e-43 K Cro/C1-type HTH DNA-binding domain
DNEJFCKL_00330 6.1e-16 S BrnA antitoxin of type II toxin-antitoxin system
DNEJFCKL_00331 2.6e-25 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
DNEJFCKL_00334 3.1e-67 L Helix-turn-helix domain
DNEJFCKL_00335 3.4e-127 insK L Integrase core domain
DNEJFCKL_00336 1e-30 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00337 8.3e-128 V Abi-like protein
DNEJFCKL_00338 3.9e-16 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00340 2.6e-73
DNEJFCKL_00341 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00342 5.5e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DNEJFCKL_00343 1.6e-146 metQ P NLPA lipoprotein
DNEJFCKL_00344 1.7e-156 S Sucrose-6F-phosphate phosphohydrolase
DNEJFCKL_00345 1.8e-225 S Peptidase dimerisation domain
DNEJFCKL_00346 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DNEJFCKL_00347 4.5e-31
DNEJFCKL_00348 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DNEJFCKL_00349 2.8e-165 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DNEJFCKL_00350 9.9e-80 S Protein of unknown function (DUF3000)
DNEJFCKL_00351 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
DNEJFCKL_00352 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DNEJFCKL_00353 1.8e-133 yebE S DUF218 domain
DNEJFCKL_00354 4e-130 E Psort location Cytoplasmic, score 8.87
DNEJFCKL_00355 1.1e-158 O Thioredoxin
DNEJFCKL_00356 1.2e-158 msbA2 3.6.3.44 V ABC transporter transmembrane region
DNEJFCKL_00357 3.6e-137 3.6.3.44 V ABC transporter
DNEJFCKL_00358 0.0 KLT Lanthionine synthetase C-like protein
DNEJFCKL_00359 6.5e-122 K helix_turn_helix, Lux Regulon
DNEJFCKL_00360 8.2e-96 2.7.13.3 T Histidine kinase
DNEJFCKL_00363 8.3e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DNEJFCKL_00364 3e-147 S phosphoesterase or phosphohydrolase
DNEJFCKL_00366 4.3e-126 XK26_04895
DNEJFCKL_00367 0.0 KL Type III restriction enzyme res subunit
DNEJFCKL_00368 8.1e-34 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
DNEJFCKL_00369 2.1e-40 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
DNEJFCKL_00370 1.5e-172 3.1.21.4 V Type III restriction enzyme res subunit
DNEJFCKL_00371 1.3e-84 S Protein of unknown function DUF262
DNEJFCKL_00373 0.0 S Protein of unknown function DUF262
DNEJFCKL_00374 2.7e-54 S Protein of unknown function DUF262
DNEJFCKL_00376 1.2e-123 3.2.1.8 S alpha beta
DNEJFCKL_00377 1e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DNEJFCKL_00378 1.3e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DNEJFCKL_00379 1.3e-113 kcsA U Ion channel
DNEJFCKL_00380 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DNEJFCKL_00381 6.1e-109 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DNEJFCKL_00382 0.0 ecfA GP ABC transporter, ATP-binding protein
DNEJFCKL_00383 2.4e-47 yhbY J CRS1_YhbY
DNEJFCKL_00384 4.8e-145 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DNEJFCKL_00385 6.3e-201 S Glycosyltransferase, group 2 family protein
DNEJFCKL_00386 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DNEJFCKL_00387 8.1e-221 E Aminotransferase class I and II
DNEJFCKL_00388 1.9e-144 bioM P ATPases associated with a variety of cellular activities
DNEJFCKL_00389 8.1e-307 2.8.2.22 S Arylsulfotransferase Ig-like domain
DNEJFCKL_00390 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DNEJFCKL_00391 0.0 S Tetratricopeptide repeat
DNEJFCKL_00392 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DNEJFCKL_00393 8.2e-213 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DNEJFCKL_00394 8.4e-84 ykoE S ABC-type cobalt transport system, permease component
DNEJFCKL_00395 1.2e-264 ykoD P ATPases associated with a variety of cellular activities
DNEJFCKL_00396 3.1e-145 cbiQ P Cobalt transport protein
DNEJFCKL_00397 2.3e-251 argE E Peptidase dimerisation domain
DNEJFCKL_00398 3.6e-93 S Protein of unknown function (DUF3043)
DNEJFCKL_00399 5.4e-246 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DNEJFCKL_00400 8.6e-142 S Domain of unknown function (DUF4191)
DNEJFCKL_00401 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
DNEJFCKL_00402 5.2e-42 V DNA modification
DNEJFCKL_00403 2.2e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
DNEJFCKL_00404 1.5e-17 L HNH endonuclease
DNEJFCKL_00406 4.5e-18
DNEJFCKL_00407 1.5e-97 yvdD 3.2.2.10 S Possible lysine decarboxylase
DNEJFCKL_00408 3.3e-158 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DNEJFCKL_00409 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DNEJFCKL_00410 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DNEJFCKL_00411 1.9e-98
DNEJFCKL_00412 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DNEJFCKL_00413 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DNEJFCKL_00414 1.8e-178 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DNEJFCKL_00415 6.4e-243 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DNEJFCKL_00416 1e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DNEJFCKL_00417 2.3e-82 argR K Regulates arginine biosynthesis genes
DNEJFCKL_00418 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DNEJFCKL_00419 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
DNEJFCKL_00420 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DNEJFCKL_00421 8.6e-137 S Putative ABC-transporter type IV
DNEJFCKL_00422 0.0 S Protein of unknown function (DUF975)
DNEJFCKL_00423 1.3e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DNEJFCKL_00424 3.7e-148 L Tetratricopeptide repeat
DNEJFCKL_00425 3.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DNEJFCKL_00426 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DNEJFCKL_00427 3e-116 trkA P TrkA-N domain
DNEJFCKL_00428 2.1e-266 trkB P Cation transport protein
DNEJFCKL_00429 2.9e-176 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DNEJFCKL_00430 1.4e-261 recN L May be involved in recombinational repair of damaged DNA
DNEJFCKL_00431 1.3e-122 S Haloacid dehalogenase-like hydrolase
DNEJFCKL_00432 9.1e-122 S ABC-2 family transporter protein
DNEJFCKL_00433 7.8e-174 V ATPases associated with a variety of cellular activities
DNEJFCKL_00434 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
DNEJFCKL_00435 4.3e-23 C Acetamidase/Formamidase family
DNEJFCKL_00436 1.6e-44 L transposition
DNEJFCKL_00437 0.0 S Histidine phosphatase superfamily (branch 2)
DNEJFCKL_00438 7.4e-95 S Pyridoxamine 5'-phosphate oxidase
DNEJFCKL_00439 1.9e-25 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00440 1.1e-95 bcp 1.11.1.15 O Redoxin
DNEJFCKL_00441 2.3e-57 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DNEJFCKL_00442 1.4e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DNEJFCKL_00443 9.1e-164 IQ Enoyl-(Acyl carrier protein) reductase
DNEJFCKL_00444 2e-142
DNEJFCKL_00445 4.3e-174 G Fic/DOC family
DNEJFCKL_00446 1e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
DNEJFCKL_00447 4.6e-233 EGP Major facilitator Superfamily
DNEJFCKL_00448 2.1e-285 thrC 4.2.3.1 E Threonine synthase N terminus
DNEJFCKL_00449 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DNEJFCKL_00450 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DNEJFCKL_00451 3.2e-101
DNEJFCKL_00452 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DNEJFCKL_00453 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DNEJFCKL_00455 5.8e-12
DNEJFCKL_00458 1.3e-61 ydhQ 2.7.11.1 MU cell adhesion
DNEJFCKL_00462 9.4e-10 S Helix-turn-helix domain
DNEJFCKL_00463 6.3e-57 S Helix-turn-helix domain
DNEJFCKL_00465 1.5e-140 I alpha/beta hydrolase fold
DNEJFCKL_00466 3.9e-31 I alpha/beta hydrolase fold
DNEJFCKL_00467 2.8e-145 cobB2 K Sir2 family
DNEJFCKL_00468 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DNEJFCKL_00469 1e-308 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DNEJFCKL_00470 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DNEJFCKL_00471 1.5e-07
DNEJFCKL_00472 8.3e-34
DNEJFCKL_00473 2.6e-194 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DNEJFCKL_00474 1.1e-189 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DNEJFCKL_00475 4e-104
DNEJFCKL_00476 0.0 typA T Elongation factor G C-terminus
DNEJFCKL_00477 3.7e-249 naiP U Sugar (and other) transporter
DNEJFCKL_00478 1.4e-150 nrtR 3.6.1.55 F NUDIX hydrolase
DNEJFCKL_00479 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DNEJFCKL_00480 2e-177 xerD D recombinase XerD
DNEJFCKL_00481 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DNEJFCKL_00482 2.1e-25 rpmI J Ribosomal protein L35
DNEJFCKL_00483 3.7e-104 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DNEJFCKL_00484 1.2e-137 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DNEJFCKL_00485 1.5e-197 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DNEJFCKL_00486 9.3e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DNEJFCKL_00487 1.8e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DNEJFCKL_00488 1.3e-187 galM 5.1.3.3 G Aldose 1-epimerase
DNEJFCKL_00489 4.1e-37
DNEJFCKL_00490 1.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DNEJFCKL_00491 1.3e-271 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DNEJFCKL_00492 1.8e-184 V Acetyltransferase (GNAT) domain
DNEJFCKL_00493 1.8e-287 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DNEJFCKL_00494 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DNEJFCKL_00495 9e-95 3.6.1.55 F NUDIX domain
DNEJFCKL_00496 0.0 P Belongs to the ABC transporter superfamily
DNEJFCKL_00497 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00498 2.5e-187 dppB EP Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00499 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
DNEJFCKL_00500 6.6e-218 GK ROK family
DNEJFCKL_00501 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
DNEJFCKL_00502 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
DNEJFCKL_00503 1.6e-27
DNEJFCKL_00504 3.8e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
DNEJFCKL_00505 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
DNEJFCKL_00506 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
DNEJFCKL_00507 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DNEJFCKL_00508 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DNEJFCKL_00509 2.8e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DNEJFCKL_00510 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DNEJFCKL_00511 4.2e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DNEJFCKL_00512 8.7e-151 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DNEJFCKL_00513 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DNEJFCKL_00514 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DNEJFCKL_00515 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DNEJFCKL_00516 7e-92 mraZ K Belongs to the MraZ family
DNEJFCKL_00517 0.0 L DNA helicase
DNEJFCKL_00518 8.7e-218 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DNEJFCKL_00519 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DNEJFCKL_00520 1e-53 M Lysin motif
DNEJFCKL_00521 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DNEJFCKL_00522 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DNEJFCKL_00523 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DNEJFCKL_00524 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DNEJFCKL_00525 1.6e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DNEJFCKL_00526 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DNEJFCKL_00527 2.2e-196
DNEJFCKL_00528 3.7e-188 V N-Acetylmuramoyl-L-alanine amidase
DNEJFCKL_00529 9.2e-82
DNEJFCKL_00530 9.2e-57 T helix_turn_helix, Lux Regulon
DNEJFCKL_00531 1.6e-30 2.7.13.3 T Histidine kinase
DNEJFCKL_00532 2.4e-113 ytrE V ATPases associated with a variety of cellular activities
DNEJFCKL_00533 1.8e-218 EGP Major facilitator Superfamily
DNEJFCKL_00534 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DNEJFCKL_00535 1.1e-217 S Domain of unknown function (DUF5067)
DNEJFCKL_00536 6.8e-264 glnA2 6.3.1.2 E glutamine synthetase
DNEJFCKL_00537 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DNEJFCKL_00538 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DNEJFCKL_00539 1.5e-122
DNEJFCKL_00540 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DNEJFCKL_00541 1.6e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DNEJFCKL_00542 1.2e-258 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DNEJFCKL_00543 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DNEJFCKL_00544 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DNEJFCKL_00545 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DNEJFCKL_00546 4.5e-31 3.1.21.3 V DivIVA protein
DNEJFCKL_00547 6.9e-41 yggT S YGGT family
DNEJFCKL_00548 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DNEJFCKL_00549 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DNEJFCKL_00550 1.1e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DNEJFCKL_00551 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DNEJFCKL_00552 1e-105 S Pilus assembly protein, PilO
DNEJFCKL_00553 1.8e-165 pilN NU PFAM Fimbrial assembly family protein
DNEJFCKL_00554 3e-190 pilM NU Type IV pilus assembly protein PilM;
DNEJFCKL_00555 5.3e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DNEJFCKL_00556 0.0
DNEJFCKL_00557 7.3e-231 pilC U Type II secretion system (T2SS), protein F
DNEJFCKL_00558 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
DNEJFCKL_00559 2.1e-104 S Prokaryotic N-terminal methylation motif
DNEJFCKL_00560 5.4e-136 ppdC NU Prokaryotic N-terminal methylation motif
DNEJFCKL_00561 0.0 pulE NU Type II/IV secretion system protein
DNEJFCKL_00562 0.0 pilT NU Type II/IV secretion system protein
DNEJFCKL_00563 0.0
DNEJFCKL_00564 3.7e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DNEJFCKL_00565 1.1e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DNEJFCKL_00566 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DNEJFCKL_00567 3e-60 S Thiamine-binding protein
DNEJFCKL_00568 1.1e-192 K helix_turn _helix lactose operon repressor
DNEJFCKL_00569 2.8e-241 lacY P LacY proton/sugar symporter
DNEJFCKL_00570 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DNEJFCKL_00571 3.2e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00572 9.1e-206 P NMT1/THI5 like
DNEJFCKL_00573 5.6e-215 iunH1 3.2.2.1 F nucleoside hydrolase
DNEJFCKL_00574 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DNEJFCKL_00575 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
DNEJFCKL_00576 0.0 I acetylesterase activity
DNEJFCKL_00577 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DNEJFCKL_00578 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DNEJFCKL_00579 4e-239 2.7.11.1 NU Tfp pilus assembly protein FimV
DNEJFCKL_00581 6.5e-75 S Protein of unknown function (DUF3052)
DNEJFCKL_00582 1e-154 lon T Belongs to the peptidase S16 family
DNEJFCKL_00583 1.7e-285 S Zincin-like metallopeptidase
DNEJFCKL_00584 1.8e-281 uvrD2 3.6.4.12 L DNA helicase
DNEJFCKL_00585 1.1e-270 mphA S Aminoglycoside phosphotransferase
DNEJFCKL_00586 3.6e-32 S Protein of unknown function (DUF3107)
DNEJFCKL_00587 2.5e-172 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DNEJFCKL_00588 2.8e-117 S Vitamin K epoxide reductase
DNEJFCKL_00589 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DNEJFCKL_00590 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DNEJFCKL_00591 5.9e-12
DNEJFCKL_00592 3.4e-17 yccF S Inner membrane component domain
DNEJFCKL_00593 1.1e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DNEJFCKL_00594 1.4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DNEJFCKL_00595 3.7e-270 pip 3.4.11.5 S alpha/beta hydrolase fold
DNEJFCKL_00596 0.0 tcsS2 T Histidine kinase
DNEJFCKL_00597 5.5e-130 K helix_turn_helix, Lux Regulon
DNEJFCKL_00598 0.0 MV MacB-like periplasmic core domain
DNEJFCKL_00599 5.1e-142 V ABC transporter, ATP-binding protein
DNEJFCKL_00600 8.2e-193 K helix_turn_helix ASNC type
DNEJFCKL_00601 6.9e-150 P Cobalt transport protein
DNEJFCKL_00602 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
DNEJFCKL_00603 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
DNEJFCKL_00604 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
DNEJFCKL_00605 1.1e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DNEJFCKL_00606 2.6e-82 yraN L Belongs to the UPF0102 family
DNEJFCKL_00607 1.8e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
DNEJFCKL_00608 5.9e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DNEJFCKL_00609 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DNEJFCKL_00610 7.5e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DNEJFCKL_00611 4.8e-117 safC S O-methyltransferase
DNEJFCKL_00612 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DNEJFCKL_00614 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DNEJFCKL_00615 5.6e-300 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DNEJFCKL_00616 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DNEJFCKL_00617 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
DNEJFCKL_00618 6.1e-244 pbuX F Permease family
DNEJFCKL_00619 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DNEJFCKL_00620 0.0 pcrA 3.6.4.12 L DNA helicase
DNEJFCKL_00621 1.7e-61 S Domain of unknown function (DUF4418)
DNEJFCKL_00622 1.4e-215 V FtsX-like permease family
DNEJFCKL_00623 1.7e-148 lolD V ABC transporter
DNEJFCKL_00624 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DNEJFCKL_00625 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DNEJFCKL_00626 5.6e-129 pgm3 G Phosphoglycerate mutase family
DNEJFCKL_00627 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DNEJFCKL_00628 2.5e-36
DNEJFCKL_00629 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DNEJFCKL_00630 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DNEJFCKL_00631 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DNEJFCKL_00632 9.3e-57 3.4.23.43 S Type IV leader peptidase family
DNEJFCKL_00633 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DNEJFCKL_00634 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DNEJFCKL_00635 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DNEJFCKL_00636 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
DNEJFCKL_00637 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DNEJFCKL_00638 0.0 S L,D-transpeptidase catalytic domain
DNEJFCKL_00639 2.8e-290 sufB O FeS assembly protein SufB
DNEJFCKL_00640 1e-234 sufD O FeS assembly protein SufD
DNEJFCKL_00641 1.3e-142 sufC O FeS assembly ATPase SufC
DNEJFCKL_00642 1.9e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DNEJFCKL_00643 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
DNEJFCKL_00644 2.7e-108 yitW S Iron-sulfur cluster assembly protein
DNEJFCKL_00645 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DNEJFCKL_00646 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
DNEJFCKL_00648 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DNEJFCKL_00649 2e-55 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DNEJFCKL_00650 5.9e-208 phoH T PhoH-like protein
DNEJFCKL_00651 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DNEJFCKL_00652 1.2e-250 corC S CBS domain
DNEJFCKL_00653 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DNEJFCKL_00654 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DNEJFCKL_00655 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DNEJFCKL_00656 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DNEJFCKL_00657 6e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DNEJFCKL_00658 4.2e-269 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00660 2.1e-225 G Transmembrane secretion effector
DNEJFCKL_00661 1.9e-121 K Bacterial regulatory proteins, tetR family
DNEJFCKL_00663 1.1e-39 nrdH O Glutaredoxin
DNEJFCKL_00664 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
DNEJFCKL_00665 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNEJFCKL_00667 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DNEJFCKL_00668 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DNEJFCKL_00670 2.6e-30 EGP Major facilitator Superfamily
DNEJFCKL_00671 1.3e-25 yhjX EGP Major facilitator Superfamily
DNEJFCKL_00672 3.8e-195 S alpha beta
DNEJFCKL_00673 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DNEJFCKL_00674 1.8e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNEJFCKL_00675 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNEJFCKL_00676 7.7e-73 K Acetyltransferase (GNAT) domain
DNEJFCKL_00678 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
DNEJFCKL_00679 1.1e-133 S UPF0126 domain
DNEJFCKL_00680 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
DNEJFCKL_00681 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DNEJFCKL_00682 3e-234 hemN H Involved in the biosynthesis of porphyrin-containing compound
DNEJFCKL_00683 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DNEJFCKL_00684 6.9e-289 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
DNEJFCKL_00685 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
DNEJFCKL_00686 2.2e-233 F Psort location CytoplasmicMembrane, score 10.00
DNEJFCKL_00687 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DNEJFCKL_00688 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DNEJFCKL_00689 2e-74
DNEJFCKL_00690 2.2e-248 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DNEJFCKL_00691 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DNEJFCKL_00692 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DNEJFCKL_00693 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
DNEJFCKL_00694 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DNEJFCKL_00695 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DNEJFCKL_00696 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DNEJFCKL_00697 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DNEJFCKL_00698 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DNEJFCKL_00699 1.1e-277 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DNEJFCKL_00700 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DNEJFCKL_00701 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DNEJFCKL_00702 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DNEJFCKL_00703 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DNEJFCKL_00704 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DNEJFCKL_00705 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DNEJFCKL_00707 8.8e-109 J Acetyltransferase (GNAT) domain
DNEJFCKL_00708 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DNEJFCKL_00709 2.1e-218 yxjG_1 E Psort location Cytoplasmic, score 8.87
DNEJFCKL_00710 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DNEJFCKL_00711 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
DNEJFCKL_00712 8.8e-139 S SdpI/YhfL protein family
DNEJFCKL_00713 3e-108 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DNEJFCKL_00714 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DNEJFCKL_00715 5e-125 XK27_06785 V ABC transporter
DNEJFCKL_00717 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DNEJFCKL_00718 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DNEJFCKL_00719 0.0 pip S YhgE Pip domain protein
DNEJFCKL_00720 0.0 pip S YhgE Pip domain protein
DNEJFCKL_00721 6.3e-171 yddG EG EamA-like transporter family
DNEJFCKL_00722 1.1e-186 K Helix-turn-helix XRE-family like proteins
DNEJFCKL_00724 4.7e-162 htpX O Belongs to the peptidase M48B family
DNEJFCKL_00725 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DNEJFCKL_00726 3.9e-187 ansA 3.5.1.1 EJ Asparaginase
DNEJFCKL_00727 0.0 cadA P E1-E2 ATPase
DNEJFCKL_00728 9.6e-270 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DNEJFCKL_00729 3.3e-266 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DNEJFCKL_00731 2.4e-177 mutH L DNA mismatch repair enzyme MutH
DNEJFCKL_00732 3.9e-200 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
DNEJFCKL_00733 2.5e-07
DNEJFCKL_00734 1.9e-23
DNEJFCKL_00735 1.6e-44 ydeP K HxlR-like helix-turn-helix
DNEJFCKL_00736 6.2e-82 XK27_10430 S NAD(P)H-binding
DNEJFCKL_00737 1.7e-158 yicL EG EamA-like transporter family
DNEJFCKL_00738 3.9e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
DNEJFCKL_00739 3.2e-113 K helix_turn_helix, Lux Regulon
DNEJFCKL_00740 3.5e-225 2.7.13.3 T Histidine kinase
DNEJFCKL_00741 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DNEJFCKL_00742 1.2e-131 fhaA T Protein of unknown function (DUF2662)
DNEJFCKL_00743 1.2e-72 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DNEJFCKL_00744 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DNEJFCKL_00745 1.1e-263 rodA D Belongs to the SEDS family
DNEJFCKL_00746 5.4e-262 pbpA M penicillin-binding protein
DNEJFCKL_00747 7.6e-177 T Protein tyrosine kinase
DNEJFCKL_00748 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DNEJFCKL_00749 3.8e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DNEJFCKL_00750 6.7e-209 srtA 3.4.22.70 M Sortase family
DNEJFCKL_00751 6.8e-142 S Bacterial protein of unknown function (DUF881)
DNEJFCKL_00752 3.1e-57 crgA D Involved in cell division
DNEJFCKL_00753 7.3e-240 L ribosomal rna small subunit methyltransferase
DNEJFCKL_00754 1.4e-147 gluP 3.4.21.105 S Rhomboid family
DNEJFCKL_00755 3.4e-35
DNEJFCKL_00756 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DNEJFCKL_00757 1.7e-63 I Sterol carrier protein
DNEJFCKL_00758 1.4e-41 S Protein of unknown function (DUF3073)
DNEJFCKL_00759 5.9e-205 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DNEJFCKL_00760 2.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DNEJFCKL_00761 0.0 yjjP S Threonine/Serine exporter, ThrE
DNEJFCKL_00762 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DNEJFCKL_00764 8.2e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DNEJFCKL_00765 8e-241 ytfL P Transporter associated domain
DNEJFCKL_00766 1e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DNEJFCKL_00767 3.1e-101 S Protein of unknown function DUF45
DNEJFCKL_00771 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DNEJFCKL_00772 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DNEJFCKL_00773 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
DNEJFCKL_00774 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DNEJFCKL_00775 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DNEJFCKL_00776 6.2e-90 S Protein of unknown function (DUF721)
DNEJFCKL_00777 1.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DNEJFCKL_00778 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DNEJFCKL_00779 2.5e-305 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DNEJFCKL_00780 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DNEJFCKL_00781 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
DNEJFCKL_00782 8e-91 jag S Putative single-stranded nucleic acids-binding domain
DNEJFCKL_00783 1.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DNEJFCKL_00784 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DNEJFCKL_00785 4.4e-202 parB K Belongs to the ParB family
DNEJFCKL_00786 1.2e-180 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DNEJFCKL_00787 7e-14 S Psort location Extracellular, score 8.82
DNEJFCKL_00789 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DNEJFCKL_00790 4e-13 S Domain of unknown function (DUF4143)
DNEJFCKL_00791 0.0 murJ KLT MviN-like protein
DNEJFCKL_00792 4.1e-306 murJ KLT MviN-like protein
DNEJFCKL_00793 0.0 M Conserved repeat domain
DNEJFCKL_00794 6.3e-122 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DNEJFCKL_00795 5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DNEJFCKL_00796 2.6e-109 S LytR cell envelope-related transcriptional attenuator
DNEJFCKL_00797 1.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DNEJFCKL_00798 7.8e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DNEJFCKL_00799 1.6e-197 S G5
DNEJFCKL_00801 7.5e-151 O Thioredoxin
DNEJFCKL_00802 0.0 KLT Protein tyrosine kinase
DNEJFCKL_00803 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
DNEJFCKL_00804 1.3e-54 DJ Addiction module toxin, RelE StbE family
DNEJFCKL_00805 1.3e-48 S Antitoxin component of a toxin-antitoxin (TA) module
DNEJFCKL_00806 1.7e-125 S Short repeat of unknown function (DUF308)
DNEJFCKL_00807 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_00808 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DNEJFCKL_00809 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DNEJFCKL_00810 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DNEJFCKL_00811 5.6e-187 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DNEJFCKL_00812 4.8e-179 pgi 5.3.1.9 G Belongs to the GPI family
DNEJFCKL_00813 5.4e-181 S Auxin Efflux Carrier
DNEJFCKL_00816 5.3e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DNEJFCKL_00817 1.7e-243 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DNEJFCKL_00818 3.8e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DNEJFCKL_00819 5.6e-138 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DNEJFCKL_00820 1.2e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DNEJFCKL_00821 1.1e-77 soxR K MerR, DNA binding
DNEJFCKL_00822 1.7e-195 yghZ C Aldo/keto reductase family
DNEJFCKL_00823 3.2e-58 S Protein of unknown function (DUF3039)
DNEJFCKL_00824 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DNEJFCKL_00825 8.5e-134
DNEJFCKL_00826 1.8e-113 yceD S Uncharacterized ACR, COG1399
DNEJFCKL_00827 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DNEJFCKL_00828 5.7e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DNEJFCKL_00829 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DNEJFCKL_00830 5.7e-92 ilvN 2.2.1.6 E ACT domain
DNEJFCKL_00831 2.9e-96
DNEJFCKL_00832 0.0 yjjK S ABC transporter
DNEJFCKL_00833 5.6e-152 guaA1 6.3.5.2 F Peptidase C26
DNEJFCKL_00834 5.5e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DNEJFCKL_00835 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DNEJFCKL_00836 7.6e-178 S Endonuclease/Exonuclease/phosphatase family
DNEJFCKL_00837 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DNEJFCKL_00838 1.8e-34 CP_0960 S Belongs to the UPF0109 family
DNEJFCKL_00839 6.1e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DNEJFCKL_00840 5.1e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DNEJFCKL_00841 1.9e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DNEJFCKL_00842 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DNEJFCKL_00843 8.4e-30 rpmB J Ribosomal L28 family
DNEJFCKL_00844 0.0 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00845 2.1e-228 yxiO S Vacuole effluxer Atg22 like
DNEJFCKL_00846 1.9e-127 gntR K FCD
DNEJFCKL_00847 6.2e-83 gntK 2.7.1.12 F Shikimate kinase
DNEJFCKL_00848 6e-228 gnuT EG GntP family permease
DNEJFCKL_00850 2e-166 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
DNEJFCKL_00851 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DNEJFCKL_00852 1.8e-124 K Bacterial regulatory proteins, tetR family
DNEJFCKL_00853 2.1e-227 MA20_36090 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00854 3.8e-229 MA20_36090 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00855 1.7e-137 M Mechanosensitive ion channel
DNEJFCKL_00856 7.4e-179 S CAAX protease self-immunity
DNEJFCKL_00857 2.6e-214 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DNEJFCKL_00858 2.8e-141 U Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00859 1.5e-156 U Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00860 5.8e-219 P Bacterial extracellular solute-binding protein
DNEJFCKL_00861 2.6e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DNEJFCKL_00862 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DNEJFCKL_00863 2.3e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
DNEJFCKL_00864 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DNEJFCKL_00865 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
DNEJFCKL_00866 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DNEJFCKL_00867 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DNEJFCKL_00868 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DNEJFCKL_00869 3e-268 S Calcineurin-like phosphoesterase
DNEJFCKL_00872 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DNEJFCKL_00873 6.1e-100 S Protein of unknown function (DUF805)
DNEJFCKL_00874 7e-184
DNEJFCKL_00875 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DNEJFCKL_00876 6.1e-263 EGP Major facilitator Superfamily
DNEJFCKL_00877 4.9e-96 S GtrA-like protein
DNEJFCKL_00878 6.7e-62 S Macrophage migration inhibitory factor (MIF)
DNEJFCKL_00879 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DNEJFCKL_00880 0.0 pepD E Peptidase family C69
DNEJFCKL_00881 1.1e-106 S Phosphatidylethanolamine-binding protein
DNEJFCKL_00882 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DNEJFCKL_00883 6e-39 ptsH G PTS HPr component phosphorylation site
DNEJFCKL_00884 7.3e-181 K helix_turn _helix lactose operon repressor
DNEJFCKL_00885 4.2e-193 holB 2.7.7.7 L DNA polymerase III
DNEJFCKL_00886 4.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DNEJFCKL_00887 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DNEJFCKL_00888 6.7e-191 3.6.1.27 I PAP2 superfamily
DNEJFCKL_00889 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
DNEJFCKL_00890 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
DNEJFCKL_00891 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DNEJFCKL_00892 3.7e-24 S Beta-L-arabinofuranosidase, GH127
DNEJFCKL_00893 5e-101 S Protein of unknown function, DUF624
DNEJFCKL_00894 3.8e-185 G beta-fructofuranosidase activity
DNEJFCKL_00895 8.3e-163 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00896 2.3e-168 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00897 4.4e-294 G Bacterial extracellular solute-binding protein
DNEJFCKL_00898 6.4e-206 abf G Glycosyl hydrolases family 43
DNEJFCKL_00899 5.4e-195 K helix_turn _helix lactose operon repressor
DNEJFCKL_00900 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
DNEJFCKL_00901 2.7e-256 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DNEJFCKL_00902 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DNEJFCKL_00903 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DNEJFCKL_00904 8.4e-301 S Calcineurin-like phosphoesterase
DNEJFCKL_00905 2.4e-115
DNEJFCKL_00906 9.4e-34 2.7.13.3 T Histidine kinase
DNEJFCKL_00907 4e-45 K helix_turn_helix, Lux Regulon
DNEJFCKL_00908 4.8e-31
DNEJFCKL_00909 9.9e-67
DNEJFCKL_00910 5.1e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DNEJFCKL_00911 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
DNEJFCKL_00912 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DNEJFCKL_00913 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DNEJFCKL_00914 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DNEJFCKL_00915 1.1e-96 K Bacterial regulatory proteins, tetR family
DNEJFCKL_00916 1.6e-193 S Psort location CytoplasmicMembrane, score
DNEJFCKL_00917 7e-217 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DNEJFCKL_00918 5.2e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
DNEJFCKL_00919 4.3e-59 U TadE-like protein
DNEJFCKL_00920 1.3e-42 S Protein of unknown function (DUF4244)
DNEJFCKL_00921 1.7e-88 gspF NU Type II secretion system (T2SS), protein F
DNEJFCKL_00922 6.9e-125 U Type ii secretion system
DNEJFCKL_00923 6.1e-185 cpaF U Type II IV secretion system protein
DNEJFCKL_00924 5.5e-141 cpaE D bacterial-type flagellum organization
DNEJFCKL_00926 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DNEJFCKL_00927 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DNEJFCKL_00928 1.5e-87
DNEJFCKL_00929 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DNEJFCKL_00930 2.3e-206 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DNEJFCKL_00931 0.0 G Bacterial Ig-like domain (group 4)
DNEJFCKL_00932 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
DNEJFCKL_00933 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DNEJFCKL_00934 9.3e-147 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00935 3.1e-167 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00936 3.3e-07 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_00937 1.1e-242 G Bacterial extracellular solute-binding protein
DNEJFCKL_00938 6.3e-193 K Periplasmic binding protein domain
DNEJFCKL_00939 0.0 ubiB S ABC1 family
DNEJFCKL_00940 1e-27 S granule-associated protein
DNEJFCKL_00941 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DNEJFCKL_00942 1.1e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DNEJFCKL_00943 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DNEJFCKL_00944 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DNEJFCKL_00945 1e-54 glnB K Nitrogen regulatory protein P-II
DNEJFCKL_00946 1.2e-236 amt U Ammonium Transporter Family
DNEJFCKL_00947 8.6e-168 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DNEJFCKL_00948 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
DNEJFCKL_00949 4e-195 XK27_01805 M Glycosyltransferase like family 2
DNEJFCKL_00950 3.1e-306 pepD E Peptidase family C69
DNEJFCKL_00952 4.4e-214 M cell wall binding repeat
DNEJFCKL_00953 6e-38 nrdH O Glutaredoxin
DNEJFCKL_00954 5.9e-225 S Putative ABC-transporter type IV
DNEJFCKL_00955 0.0 pip S YhgE Pip domain protein
DNEJFCKL_00956 3e-269 pip S YhgE Pip domain protein
DNEJFCKL_00957 1.3e-87 K Psort location Cytoplasmic, score 8.87
DNEJFCKL_00958 1.1e-61 S FMN_bind
DNEJFCKL_00959 5.3e-150 macB V ABC transporter, ATP-binding protein
DNEJFCKL_00960 5.9e-201 Z012_06715 V FtsX-like permease family
DNEJFCKL_00962 8e-220 macB_2 V ABC transporter permease
DNEJFCKL_00963 4.2e-231 S Predicted membrane protein (DUF2318)
DNEJFCKL_00964 4.1e-92 tpd P Fe2+ transport protein
DNEJFCKL_00965 5.8e-295 efeU_1 P Iron permease FTR1 family
DNEJFCKL_00966 4.4e-237 G MFS/sugar transport protein
DNEJFCKL_00967 1.4e-117 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DNEJFCKL_00968 0.0 lmrA2 V ABC transporter transmembrane region
DNEJFCKL_00969 2.7e-285 lmrA1 V ABC transporter, ATP-binding protein
DNEJFCKL_00970 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DNEJFCKL_00971 1.8e-182 1.1.1.65 C Aldo/keto reductase family
DNEJFCKL_00972 1.9e-26 thiS 2.8.1.10 H ThiS family
DNEJFCKL_00973 2.6e-129 thiF 2.7.7.73, 2.7.7.80 H ThiF family
DNEJFCKL_00974 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DNEJFCKL_00975 9.9e-275 cycA E Amino acid permease
DNEJFCKL_00976 2.5e-89 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00977 7.6e-211 M LPXTG cell wall anchor motif
DNEJFCKL_00978 0.0 inlJ M domain protein
DNEJFCKL_00979 3.3e-179 3.4.22.70 M Sortase family
DNEJFCKL_00980 1.2e-77 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_00981 1.2e-227 P Sodium/hydrogen exchanger family
DNEJFCKL_00982 0.0 V FtsX-like permease family
DNEJFCKL_00983 4.1e-270 aroP E aromatic amino acid transport protein AroP K03293
DNEJFCKL_00984 8.8e-12 S Protein of unknown function, DUF624
DNEJFCKL_00985 1.4e-187 K helix_turn _helix lactose operon repressor
DNEJFCKL_00986 4.9e-39 G beta-mannosidase
DNEJFCKL_00987 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DNEJFCKL_00988 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DNEJFCKL_00989 8.9e-83 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DNEJFCKL_00990 1e-83 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DNEJFCKL_00991 9.7e-85
DNEJFCKL_00992 4.7e-175 MA20_14895 S Conserved hypothetical protein 698
DNEJFCKL_00993 9.5e-186 C Na H antiporter family protein
DNEJFCKL_00994 2.6e-158 korD 1.2.7.3 C Domain of unknown function (DUF362)
DNEJFCKL_00995 7.9e-82 2.7.1.48 F uridine kinase
DNEJFCKL_00996 8.1e-81 S ECF transporter, substrate-specific component
DNEJFCKL_00997 3.1e-137 S Sulfite exporter TauE/SafE
DNEJFCKL_00998 8.5e-139 K helix_turn_helix, arabinose operon control protein
DNEJFCKL_00999 2e-157 3.1.3.73 G Phosphoglycerate mutase family
DNEJFCKL_01000 9.9e-228 rutG F Permease family
DNEJFCKL_01001 2.1e-126 S Enoyl-(Acyl carrier protein) reductase
DNEJFCKL_01002 1.5e-273 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DNEJFCKL_01003 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
DNEJFCKL_01004 2.1e-141 ybbL V ATPases associated with a variety of cellular activities
DNEJFCKL_01005 2.5e-240 S Putative esterase
DNEJFCKL_01006 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DNEJFCKL_01007 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DNEJFCKL_01008 5.3e-147 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DNEJFCKL_01009 5.3e-236 patB 4.4.1.8 E Aminotransferase, class I II
DNEJFCKL_01010 1.8e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DNEJFCKL_01011 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
DNEJFCKL_01012 7.1e-144 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DNEJFCKL_01013 1.2e-79 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DNEJFCKL_01014 1.3e-87 M Protein of unknown function (DUF3737)
DNEJFCKL_01015 3.9e-142 azlC E AzlC protein
DNEJFCKL_01016 1e-51 azlD E Branched-chain amino acid transport protein (AzlD)
DNEJFCKL_01017 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
DNEJFCKL_01018 6.2e-40 ybdD S Selenoprotein, putative
DNEJFCKL_01019 4.8e-179 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DNEJFCKL_01020 0.0 S Uncharacterised protein family (UPF0182)
DNEJFCKL_01021 1.1e-92 2.3.1.183 M Acetyltransferase (GNAT) domain
DNEJFCKL_01022 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DNEJFCKL_01023 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DNEJFCKL_01024 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DNEJFCKL_01025 2e-71 divIC D Septum formation initiator
DNEJFCKL_01026 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DNEJFCKL_01027 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DNEJFCKL_01029 1.8e-91
DNEJFCKL_01030 7.2e-283 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DNEJFCKL_01031 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DNEJFCKL_01032 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DNEJFCKL_01033 1.2e-142 yplQ S Haemolysin-III related
DNEJFCKL_01034 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DNEJFCKL_01035 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DNEJFCKL_01036 0.0 D FtsK/SpoIIIE family
DNEJFCKL_01037 5.3e-170 K Cell envelope-related transcriptional attenuator domain
DNEJFCKL_01039 1.7e-199 K Cell envelope-related transcriptional attenuator domain
DNEJFCKL_01040 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DNEJFCKL_01041 0.0 S Glycosyl transferase, family 2
DNEJFCKL_01042 8.7e-223
DNEJFCKL_01043 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DNEJFCKL_01044 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DNEJFCKL_01045 2.5e-138 ctsW S Phosphoribosyl transferase domain
DNEJFCKL_01046 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DNEJFCKL_01047 2e-129 T Response regulator receiver domain protein
DNEJFCKL_01048 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DNEJFCKL_01049 3e-102 carD K CarD-like/TRCF domain
DNEJFCKL_01050 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DNEJFCKL_01051 1.7e-140 znuB U ABC 3 transport family
DNEJFCKL_01052 2e-160 znuC P ATPases associated with a variety of cellular activities
DNEJFCKL_01053 4.2e-171 P Zinc-uptake complex component A periplasmic
DNEJFCKL_01054 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DNEJFCKL_01055 8.3e-255 rpsA J Ribosomal protein S1
DNEJFCKL_01056 1.5e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DNEJFCKL_01057 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DNEJFCKL_01058 5.4e-14 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DNEJFCKL_01059 2.8e-157 terC P Integral membrane protein, TerC family
DNEJFCKL_01060 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
DNEJFCKL_01062 2.9e-18 relB L RelB antitoxin
DNEJFCKL_01064 7.2e-196 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DNEJFCKL_01065 7.1e-46 3.6.3.21 E ATPases associated with a variety of cellular activities
DNEJFCKL_01066 4e-56 3.6.3.21 E ATPases associated with a variety of cellular activities
DNEJFCKL_01067 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
DNEJFCKL_01068 8.2e-101 E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01069 5.1e-37 pcrA1 3.6.4.12 F DNA helicase
DNEJFCKL_01070 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DNEJFCKL_01071 6.1e-245 hsdM 2.1.1.72 V HsdM N-terminal domain
DNEJFCKL_01072 1.8e-37 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
DNEJFCKL_01073 3.1e-74 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DNEJFCKL_01074 3.5e-252 yhjE EGP Sugar (and other) transporter
DNEJFCKL_01075 5.3e-279 scrT G Transporter major facilitator family protein
DNEJFCKL_01076 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01077 1.1e-161 amyD3 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01078 3.3e-223 G Bacterial extracellular solute-binding protein
DNEJFCKL_01079 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
DNEJFCKL_01080 1.5e-115 S Protein of unknown function, DUF624
DNEJFCKL_01081 1.2e-296 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DNEJFCKL_01082 1.1e-195 K helix_turn _helix lactose operon repressor
DNEJFCKL_01083 1.4e-29 E Receptor family ligand binding region
DNEJFCKL_01084 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNEJFCKL_01085 5.1e-144 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DNEJFCKL_01086 3.8e-279 clcA P Voltage gated chloride channel
DNEJFCKL_01088 1.8e-240 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DNEJFCKL_01089 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DNEJFCKL_01090 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DNEJFCKL_01091 4.6e-310 E ABC transporter, substrate-binding protein, family 5
DNEJFCKL_01092 5.3e-252 EGP Major facilitator Superfamily
DNEJFCKL_01093 1.2e-172 yjfF U Branched-chain amino acid transport system / permease component
DNEJFCKL_01094 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
DNEJFCKL_01095 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
DNEJFCKL_01096 2.4e-165 G Periplasmic binding protein domain
DNEJFCKL_01097 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
DNEJFCKL_01098 1.5e-286 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DNEJFCKL_01099 4.5e-134 KT Transcriptional regulatory protein, C terminal
DNEJFCKL_01100 4.4e-250 rarA L Recombination factor protein RarA
DNEJFCKL_01101 0.0 L DEAD DEAH box helicase
DNEJFCKL_01102 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DNEJFCKL_01103 1e-199 gluD E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01104 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01105 2.6e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
DNEJFCKL_01106 6.2e-137 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DNEJFCKL_01107 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
DNEJFCKL_01108 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01109 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DNEJFCKL_01110 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DNEJFCKL_01111 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DNEJFCKL_01112 4.6e-140 3.5.2.10 S Creatinine amidohydrolase
DNEJFCKL_01113 5e-246 proP EGP Sugar (and other) transporter
DNEJFCKL_01114 1.6e-285 purR QT Purine catabolism regulatory protein-like family
DNEJFCKL_01115 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
DNEJFCKL_01116 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DNEJFCKL_01117 4.6e-188 uspA T Belongs to the universal stress protein A family
DNEJFCKL_01118 1.2e-182 S Protein of unknown function (DUF3027)
DNEJFCKL_01119 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
DNEJFCKL_01120 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DNEJFCKL_01121 6.8e-133 KT Response regulator receiver domain protein
DNEJFCKL_01122 1.3e-124
DNEJFCKL_01124 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DNEJFCKL_01125 8.5e-77 S LytR cell envelope-related transcriptional attenuator
DNEJFCKL_01126 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DNEJFCKL_01127 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
DNEJFCKL_01128 1.6e-174 S Protein of unknown function DUF58
DNEJFCKL_01129 3.6e-91
DNEJFCKL_01130 1.6e-191 S von Willebrand factor (vWF) type A domain
DNEJFCKL_01131 5e-182 S von Willebrand factor (vWF) type A domain
DNEJFCKL_01132 5.3e-67
DNEJFCKL_01133 5.6e-53
DNEJFCKL_01134 1.3e-276 S PGAP1-like protein
DNEJFCKL_01135 2.1e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DNEJFCKL_01136 0.0 S Lysylphosphatidylglycerol synthase TM region
DNEJFCKL_01137 1.4e-41 hup L Belongs to the bacterial histone-like protein family
DNEJFCKL_01138 1.8e-57
DNEJFCKL_01139 9.7e-141 C FMN binding
DNEJFCKL_01140 2.6e-280 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DNEJFCKL_01141 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DNEJFCKL_01142 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
DNEJFCKL_01143 6e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DNEJFCKL_01144 1.3e-282 arc O AAA ATPase forming ring-shaped complexes
DNEJFCKL_01145 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DNEJFCKL_01146 2.4e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DNEJFCKL_01147 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DNEJFCKL_01148 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DNEJFCKL_01149 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DNEJFCKL_01150 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DNEJFCKL_01151 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DNEJFCKL_01153 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DNEJFCKL_01154 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DNEJFCKL_01155 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DNEJFCKL_01156 4.1e-239 carA 6.3.5.5 F Belongs to the CarA family
DNEJFCKL_01157 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DNEJFCKL_01158 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DNEJFCKL_01159 1.5e-42 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DNEJFCKL_01160 1.5e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DNEJFCKL_01161 5.8e-76 yiaC K Acetyltransferase (GNAT) domain
DNEJFCKL_01162 4.5e-71 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
DNEJFCKL_01163 8.4e-254 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DNEJFCKL_01165 7.6e-211 ykiI
DNEJFCKL_01166 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DNEJFCKL_01167 1.5e-123 3.6.1.13 L NUDIX domain
DNEJFCKL_01168 7.1e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DNEJFCKL_01169 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DNEJFCKL_01170 9.4e-101 pdtaR T Response regulator receiver domain protein
DNEJFCKL_01171 2e-163 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DNEJFCKL_01173 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
DNEJFCKL_01175 1.1e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
DNEJFCKL_01176 6.5e-226 M Glycosyl transferase 4-like domain
DNEJFCKL_01177 3.3e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DNEJFCKL_01178 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DNEJFCKL_01179 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DNEJFCKL_01180 5.4e-36
DNEJFCKL_01181 8.8e-306 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DNEJFCKL_01182 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DNEJFCKL_01183 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DNEJFCKL_01184 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
DNEJFCKL_01185 2.1e-247 EGP Major facilitator Superfamily
DNEJFCKL_01186 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DNEJFCKL_01187 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
DNEJFCKL_01188 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
DNEJFCKL_01189 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DNEJFCKL_01190 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DNEJFCKL_01191 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DNEJFCKL_01192 2.3e-89 zur P Belongs to the Fur family
DNEJFCKL_01193 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DNEJFCKL_01194 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DNEJFCKL_01195 1.2e-183 adh3 C Zinc-binding dehydrogenase
DNEJFCKL_01196 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DNEJFCKL_01197 6.8e-257 macB_8 V MacB-like periplasmic core domain
DNEJFCKL_01198 8.3e-146 M Conserved repeat domain
DNEJFCKL_01199 9.6e-135 V ATPases associated with a variety of cellular activities
DNEJFCKL_01200 4.3e-75
DNEJFCKL_01201 1.7e-13 S Domain of unknown function (DUF4143)
DNEJFCKL_01202 3.1e-127 XK27_08050 O prohibitin homologues
DNEJFCKL_01203 1.4e-43 XAC3035 O Glutaredoxin
DNEJFCKL_01204 2.8e-15 P Belongs to the ABC transporter superfamily
DNEJFCKL_01205 9.4e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DNEJFCKL_01206 4.3e-13 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DNEJFCKL_01207 4.8e-221 mtnE 2.6.1.83 E Aminotransferase class I and II
DNEJFCKL_01208 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
DNEJFCKL_01209 8.5e-193 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DNEJFCKL_01210 2e-155 metQ M NLPA lipoprotein
DNEJFCKL_01211 2.6e-199 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DNEJFCKL_01212 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
DNEJFCKL_01213 7.6e-152 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
DNEJFCKL_01214 3.6e-120 E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01215 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01216 2.7e-114 K acetyltransferase
DNEJFCKL_01220 0.0 tetP J Elongation factor G, domain IV
DNEJFCKL_01222 4e-215 ybiR P Citrate transporter
DNEJFCKL_01223 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DNEJFCKL_01224 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DNEJFCKL_01225 3.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
DNEJFCKL_01226 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DNEJFCKL_01227 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DNEJFCKL_01228 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DNEJFCKL_01229 0.0 macB_2 V ATPases associated with a variety of cellular activities
DNEJFCKL_01230 1.2e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DNEJFCKL_01231 8.4e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DNEJFCKL_01232 4e-139 sapF E ATPases associated with a variety of cellular activities
DNEJFCKL_01233 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DNEJFCKL_01234 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01235 4.8e-166 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01236 4.6e-294 E ABC transporter, substrate-binding protein, family 5
DNEJFCKL_01237 3e-240 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DNEJFCKL_01238 1e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DNEJFCKL_01239 2e-274 G Bacterial extracellular solute-binding protein
DNEJFCKL_01240 2.2e-246 G Bacterial extracellular solute-binding protein
DNEJFCKL_01241 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
DNEJFCKL_01242 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_01243 4.3e-47 L Transposase
DNEJFCKL_01244 7.2e-128 tnp7109-21 L Integrase core domain
DNEJFCKL_01245 3.9e-187 K helix_turn _helix lactose operon repressor
DNEJFCKL_01246 2.1e-260 G Bacterial extracellular solute-binding protein
DNEJFCKL_01247 6.7e-248 S zinc finger
DNEJFCKL_01248 7.5e-71 S Bacterial PH domain
DNEJFCKL_01249 1.5e-76
DNEJFCKL_01250 4.2e-302 KL Domain of unknown function (DUF3427)
DNEJFCKL_01251 4.1e-71 L Transposase IS200 like
DNEJFCKL_01252 1.1e-222 L Psort location Cytoplasmic, score 8.87
DNEJFCKL_01253 1.2e-21 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
DNEJFCKL_01254 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
DNEJFCKL_01255 1.6e-188 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DNEJFCKL_01256 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DNEJFCKL_01257 2.5e-233 aspB E Aminotransferase class-V
DNEJFCKL_01258 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DNEJFCKL_01259 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
DNEJFCKL_01260 2.2e-23
DNEJFCKL_01261 4.6e-43 V ATPases associated with a variety of cellular activities
DNEJFCKL_01262 6.5e-196 S Endonuclease/Exonuclease/phosphatase family
DNEJFCKL_01264 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DNEJFCKL_01265 2.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DNEJFCKL_01266 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DNEJFCKL_01267 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DNEJFCKL_01268 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
DNEJFCKL_01269 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DNEJFCKL_01270 1.6e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DNEJFCKL_01271 4.2e-115 K Bacterial regulatory proteins, tetR family
DNEJFCKL_01272 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
DNEJFCKL_01273 4.4e-104 K Bacterial regulatory proteins, tetR family
DNEJFCKL_01274 7.5e-239 G Transporter major facilitator family protein
DNEJFCKL_01275 2.3e-234 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DNEJFCKL_01276 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
DNEJFCKL_01277 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DNEJFCKL_01278 2.3e-108 K Bacterial regulatory proteins, tetR family
DNEJFCKL_01279 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
DNEJFCKL_01280 8e-221 lmrB U Major Facilitator Superfamily
DNEJFCKL_01281 4.5e-14 K helix_turn_helix, mercury resistance
DNEJFCKL_01282 8.9e-118 K Periplasmic binding protein domain
DNEJFCKL_01283 6.9e-213 EGP Major facilitator Superfamily
DNEJFCKL_01284 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
DNEJFCKL_01285 5.6e-178 G Transporter major facilitator family protein
DNEJFCKL_01286 7e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DNEJFCKL_01287 2.8e-105 K Bacterial regulatory proteins, tetR family
DNEJFCKL_01288 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DNEJFCKL_01289 1.3e-96 K MarR family
DNEJFCKL_01290 0.0 V ABC transporter, ATP-binding protein
DNEJFCKL_01291 0.0 V ABC transporter transmembrane region
DNEJFCKL_01292 1.4e-93 5.3.1.27 G SIS domain
DNEJFCKL_01293 8.1e-131 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
DNEJFCKL_01294 7.5e-127 glcR 3.6.4.12 K transcriptional regulator (DeoR family)
DNEJFCKL_01295 9e-135 5.3.1.15 S Pfam:DUF1498
DNEJFCKL_01296 1.2e-142 2.7.1.4 G pfkB family carbohydrate kinase
DNEJFCKL_01297 4.1e-190 G Domain of unknown function (DUF4432)
DNEJFCKL_01298 4.5e-213 xylE U Sugar (and other) transporter
DNEJFCKL_01299 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DNEJFCKL_01300 2e-154 ypfH S Phospholipase/Carboxylesterase
DNEJFCKL_01301 0.0 yjcE P Sodium/hydrogen exchanger family
DNEJFCKL_01302 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DNEJFCKL_01303 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DNEJFCKL_01304 1.5e-230 nagC GK ROK family
DNEJFCKL_01305 3.8e-243 msmE7 G Bacterial extracellular solute-binding protein
DNEJFCKL_01306 2.1e-158 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01307 3.4e-155 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01308 9e-184 lacR K Transcriptional regulator, LacI family
DNEJFCKL_01309 4.8e-79 lacS G Psort location CytoplasmicMembrane, score 10.00
DNEJFCKL_01310 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
DNEJFCKL_01311 1.5e-77 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DNEJFCKL_01312 8.2e-55 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DNEJFCKL_01313 1.9e-62 S Protein of unknown function (DUF4235)
DNEJFCKL_01314 2.9e-136 G Phosphoglycerate mutase family
DNEJFCKL_01315 3.9e-259 amyE G Bacterial extracellular solute-binding protein
DNEJFCKL_01316 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DNEJFCKL_01317 1.4e-264 amyE G Bacterial extracellular solute-binding protein
DNEJFCKL_01318 7e-187 K Periplasmic binding protein-like domain
DNEJFCKL_01319 1.7e-182 K Psort location Cytoplasmic, score
DNEJFCKL_01320 3.7e-154 msmF G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01321 4e-153 rafG G ABC transporter permease
DNEJFCKL_01322 1.2e-106 S Protein of unknown function, DUF624
DNEJFCKL_01323 2.9e-13 S Transposon-encoded protein TnpV
DNEJFCKL_01324 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
DNEJFCKL_01325 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DNEJFCKL_01326 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
DNEJFCKL_01327 2.4e-234 malE G Bacterial extracellular solute-binding protein
DNEJFCKL_01328 1.8e-246 malF G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01329 1e-162 malG G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01330 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DNEJFCKL_01331 5.4e-144 S HAD-hyrolase-like
DNEJFCKL_01332 9.7e-141 traX S TraX protein
DNEJFCKL_01333 1.3e-193 K Psort location Cytoplasmic, score
DNEJFCKL_01334 1.8e-181 M cell wall anchor domain protein
DNEJFCKL_01335 0.0 M cell wall anchor domain protein
DNEJFCKL_01336 4.7e-136 M LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01337 1.5e-184 M Cna protein B-type domain
DNEJFCKL_01338 3.5e-157 srtC 3.4.22.70 M Sortase family
DNEJFCKL_01339 6e-126 S membrane transporter protein
DNEJFCKL_01340 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
DNEJFCKL_01341 1.2e-143 S Mitochondrial biogenesis AIM24
DNEJFCKL_01342 0.0 dnaK O Heat shock 70 kDa protein
DNEJFCKL_01343 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DNEJFCKL_01344 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
DNEJFCKL_01345 4.5e-115 hspR K transcriptional regulator, MerR family
DNEJFCKL_01346 8.6e-47
DNEJFCKL_01347 3.3e-129 S HAD hydrolase, family IA, variant 3
DNEJFCKL_01349 4.2e-124 dedA S SNARE associated Golgi protein
DNEJFCKL_01350 8.7e-19 3.2.1.78 GH26 G Glycosyl hydrolase family 26
DNEJFCKL_01351 3.5e-178 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DNEJFCKL_01352 7.3e-106
DNEJFCKL_01353 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DNEJFCKL_01354 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DNEJFCKL_01355 1.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
DNEJFCKL_01356 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_01357 7.8e-302 E ABC transporter, substrate-binding protein, family 5
DNEJFCKL_01358 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
DNEJFCKL_01359 1.5e-160 S Patatin-like phospholipase
DNEJFCKL_01360 1.9e-186 K LysR substrate binding domain protein
DNEJFCKL_01361 3.3e-241 patB 4.4.1.8 E Aminotransferase, class I II
DNEJFCKL_01362 1e-119 S Phospholipase/Carboxylesterase
DNEJFCKL_01365 7.3e-33
DNEJFCKL_01366 3.9e-101 L PFAM Integrase catalytic
DNEJFCKL_01369 2.1e-25
DNEJFCKL_01374 6.1e-12 L Psort location Cytoplasmic, score
DNEJFCKL_01376 4.9e-137 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
DNEJFCKL_01379 1.2e-63 V Restriction endonuclease
DNEJFCKL_01380 4e-80
DNEJFCKL_01381 5.7e-88 pin L Resolvase, N terminal domain
DNEJFCKL_01383 9.8e-78 L helicase
DNEJFCKL_01385 1.7e-10
DNEJFCKL_01388 7.9e-11
DNEJFCKL_01395 8.2e-38
DNEJFCKL_01396 8.6e-182 L Phage integrase family
DNEJFCKL_01397 1.8e-121
DNEJFCKL_01398 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DNEJFCKL_01399 3.3e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DNEJFCKL_01400 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
DNEJFCKL_01401 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DNEJFCKL_01403 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DNEJFCKL_01404 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DNEJFCKL_01405 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DNEJFCKL_01406 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DNEJFCKL_01407 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DNEJFCKL_01408 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DNEJFCKL_01409 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DNEJFCKL_01410 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DNEJFCKL_01411 9.3e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DNEJFCKL_01412 1e-179 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DNEJFCKL_01413 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DNEJFCKL_01414 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DNEJFCKL_01415 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DNEJFCKL_01416 1.4e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DNEJFCKL_01417 2.2e-171 S Bacterial protein of unknown function (DUF881)
DNEJFCKL_01418 4.2e-45 sbp S Protein of unknown function (DUF1290)
DNEJFCKL_01419 5.9e-141 S Bacterial protein of unknown function (DUF881)
DNEJFCKL_01420 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DNEJFCKL_01421 2.5e-110 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
DNEJFCKL_01422 5.2e-128 yebC K transcriptional regulatory protein
DNEJFCKL_01423 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DNEJFCKL_01424 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DNEJFCKL_01425 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DNEJFCKL_01426 6.8e-50 yajC U Preprotein translocase subunit
DNEJFCKL_01427 3.9e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DNEJFCKL_01428 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DNEJFCKL_01429 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DNEJFCKL_01430 6.7e-246
DNEJFCKL_01431 2.3e-311 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DNEJFCKL_01432 8.2e-34
DNEJFCKL_01433 5.8e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DNEJFCKL_01434 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DNEJFCKL_01435 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DNEJFCKL_01436 1.1e-69
DNEJFCKL_01438 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DNEJFCKL_01439 0.0 pafB K WYL domain
DNEJFCKL_01440 2.1e-54
DNEJFCKL_01441 0.0 helY L DEAD DEAH box helicase
DNEJFCKL_01442 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DNEJFCKL_01443 1.1e-140 pgp 3.1.3.18 S HAD-hyrolase-like
DNEJFCKL_01444 4.6e-61
DNEJFCKL_01445 9.7e-112 K helix_turn_helix, mercury resistance
DNEJFCKL_01446 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
DNEJFCKL_01447 5.4e-36
DNEJFCKL_01448 2.5e-08
DNEJFCKL_01455 1.6e-156 S PAC2 family
DNEJFCKL_01456 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DNEJFCKL_01457 5.1e-158 G Fructosamine kinase
DNEJFCKL_01458 1.8e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DNEJFCKL_01459 4.7e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DNEJFCKL_01460 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DNEJFCKL_01461 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DNEJFCKL_01462 6.4e-41 nadR H ATPase kinase involved in NAD metabolism
DNEJFCKL_01463 1.9e-49 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
DNEJFCKL_01464 1.3e-113 pnuC H Nicotinamide mononucleotide transporter
DNEJFCKL_01465 7.6e-09 pnuC H Nicotinamide mononucleotide transporter
DNEJFCKL_01466 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DNEJFCKL_01467 2.6e-177 S Sucrose-6F-phosphate phosphohydrolase
DNEJFCKL_01468 2.4e-32 secG U Preprotein translocase SecG subunit
DNEJFCKL_01469 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DNEJFCKL_01470 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DNEJFCKL_01471 1.3e-171 whiA K May be required for sporulation
DNEJFCKL_01472 1.1e-170 rapZ S Displays ATPase and GTPase activities
DNEJFCKL_01473 1.3e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DNEJFCKL_01474 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DNEJFCKL_01475 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DNEJFCKL_01476 1.3e-179 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_01477 0.0 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_01478 6.2e-140 S Domain of unknown function (DUF4194)
DNEJFCKL_01479 2.6e-273 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_01480 2e-13
DNEJFCKL_01482 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DNEJFCKL_01483 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DNEJFCKL_01484 1.2e-299 ybiT S ABC transporter
DNEJFCKL_01485 1.6e-158 S IMP dehydrogenase activity
DNEJFCKL_01486 1.4e-278 pepC 3.4.22.40 E Peptidase C1-like family
DNEJFCKL_01487 5.7e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_01488 3.5e-142
DNEJFCKL_01489 1e-98
DNEJFCKL_01492 1e-182 cat P Cation efflux family
DNEJFCKL_01493 6.9e-75 S Psort location CytoplasmicMembrane, score
DNEJFCKL_01494 1e-220 yxjG_1 E Psort location Cytoplasmic, score 8.87
DNEJFCKL_01495 5.3e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
DNEJFCKL_01496 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DNEJFCKL_01497 4.3e-71 K MerR family regulatory protein
DNEJFCKL_01498 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
DNEJFCKL_01499 1.7e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DNEJFCKL_01500 2.1e-119 yoaP E YoaP-like
DNEJFCKL_01502 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DNEJFCKL_01503 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DNEJFCKL_01504 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
DNEJFCKL_01505 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DNEJFCKL_01506 8.4e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
DNEJFCKL_01507 0.0 comE S Competence protein
DNEJFCKL_01508 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DNEJFCKL_01509 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DNEJFCKL_01510 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
DNEJFCKL_01511 5.7e-172 corA P CorA-like Mg2+ transporter protein
DNEJFCKL_01512 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DNEJFCKL_01513 5.2e-65 3.4.22.70 M Sortase family
DNEJFCKL_01514 5.6e-83 3.4.22.70 M Sortase family
DNEJFCKL_01515 2.7e-302 M domain protein
DNEJFCKL_01516 2.7e-70 pdxH S Pfam:Pyridox_oxidase
DNEJFCKL_01517 1.3e-232 XK27_00240 K Fic/DOC family
DNEJFCKL_01519 3.3e-118
DNEJFCKL_01520 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DNEJFCKL_01521 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DNEJFCKL_01522 1.4e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DNEJFCKL_01523 7.6e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DNEJFCKL_01524 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DNEJFCKL_01525 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
DNEJFCKL_01526 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DNEJFCKL_01527 1.8e-268 G ABC transporter substrate-binding protein
DNEJFCKL_01528 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
DNEJFCKL_01529 3.3e-96 M Peptidase family M23
DNEJFCKL_01530 2.3e-60
DNEJFCKL_01534 7.4e-37 L PFAM Integrase catalytic
DNEJFCKL_01535 0.0 S Psort location CytoplasmicMembrane, score 9.99
DNEJFCKL_01536 6.2e-241 V ABC transporter permease
DNEJFCKL_01537 2.4e-156 V ABC transporter
DNEJFCKL_01538 5.1e-150 T HD domain
DNEJFCKL_01539 1e-167 S Glutamine amidotransferase domain
DNEJFCKL_01540 0.0 kup P Transport of potassium into the cell
DNEJFCKL_01541 2.2e-184 tatD L TatD related DNase
DNEJFCKL_01542 0.0 G Alpha-L-arabinofuranosidase C-terminus
DNEJFCKL_01543 6.6e-233 G Alpha galactosidase A
DNEJFCKL_01544 6.6e-221 K helix_turn _helix lactose operon repressor
DNEJFCKL_01545 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_01546 8e-126
DNEJFCKL_01547 0.0 yknV V ABC transporter
DNEJFCKL_01548 0.0 mdlA2 V ABC transporter
DNEJFCKL_01549 1.1e-214 lipA I Hydrolase, alpha beta domain protein
DNEJFCKL_01550 5e-27 S Psort location Cytoplasmic, score 8.87
DNEJFCKL_01551 3.8e-156 I alpha/beta hydrolase fold
DNEJFCKL_01552 2.2e-234 M Protein of unknown function (DUF2961)
DNEJFCKL_01553 0.0 M probably involved in cell wall
DNEJFCKL_01554 8.5e-251 3.2.1.14 GH18 S Carbohydrate binding domain
DNEJFCKL_01555 0.0 T Diguanylate cyclase, GGDEF domain
DNEJFCKL_01556 3.2e-189 lacR K Transcriptional regulator, LacI family
DNEJFCKL_01557 2.1e-244 nagA 3.5.1.25 G Amidohydrolase family
DNEJFCKL_01558 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DNEJFCKL_01559 0.0 G Glycosyl hydrolase family 20, domain 2
DNEJFCKL_01560 3e-173 2.7.1.2 GK ROK family
DNEJFCKL_01561 4.4e-164 G ABC transporter permease
DNEJFCKL_01562 7.5e-147 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01563 4.2e-242 G Bacterial extracellular solute-binding protein
DNEJFCKL_01565 2.3e-84 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DNEJFCKL_01566 2.5e-231 EGP Major facilitator Superfamily
DNEJFCKL_01567 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DNEJFCKL_01568 2e-269 KLT Domain of unknown function (DUF4032)
DNEJFCKL_01569 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
DNEJFCKL_01570 2.8e-131 K LytTr DNA-binding domain
DNEJFCKL_01571 5.2e-233 T GHKL domain
DNEJFCKL_01572 1.9e-213 clcA_2 P Voltage gated chloride channel
DNEJFCKL_01573 6.4e-179 S Psort location Cytoplasmic, score
DNEJFCKL_01574 3e-72 S GtrA-like protein
DNEJFCKL_01575 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DNEJFCKL_01577 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DNEJFCKL_01578 1.5e-293 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DNEJFCKL_01579 8.4e-81 K Psort location Cytoplasmic, score
DNEJFCKL_01580 2.2e-185 amyE G Bacterial extracellular solute-binding protein
DNEJFCKL_01581 4.4e-123 msmF G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01582 4.2e-118 rafG G ABC transporter permease
DNEJFCKL_01583 5.1e-30 S Protein of unknown function, DUF624
DNEJFCKL_01584 3.9e-87 L transposase activity
DNEJFCKL_01585 5.3e-114 L PFAM Integrase catalytic
DNEJFCKL_01586 2.2e-112 3.6.1.27 I Psort location CytoplasmicMembrane, score
DNEJFCKL_01587 3.2e-77 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
DNEJFCKL_01588 3.1e-113 vex2 V ABC transporter, ATP-binding protein
DNEJFCKL_01589 1e-213 vex1 V Efflux ABC transporter, permease protein
DNEJFCKL_01590 4.9e-241 vex3 V ABC transporter permease
DNEJFCKL_01591 9.5e-35 lacS G Psort location CytoplasmicMembrane, score 10.00
DNEJFCKL_01592 1.7e-42 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DNEJFCKL_01593 3e-229 yhjX EGP Major facilitator Superfamily
DNEJFCKL_01594 2.7e-308 trxB1 1.8.1.9 C Thioredoxin domain
DNEJFCKL_01595 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DNEJFCKL_01596 7.2e-289 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
DNEJFCKL_01597 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DNEJFCKL_01598 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DNEJFCKL_01599 0.0 eccCa D FtsK/SpoIIIE family
DNEJFCKL_01600 6.2e-156 T Forkhead associated domain
DNEJFCKL_01601 1.9e-190
DNEJFCKL_01602 4.4e-55
DNEJFCKL_01603 3.7e-188
DNEJFCKL_01604 3.2e-145
DNEJFCKL_01605 4.3e-174
DNEJFCKL_01606 1.5e-261 O Subtilase family
DNEJFCKL_01608 1.5e-43 S Proteins of 100 residues with WXG
DNEJFCKL_01609 2.4e-47 esxU S Proteins of 100 residues with WXG
DNEJFCKL_01610 1e-225 snm S WXG100 protein secretion system (Wss), protein YukD
DNEJFCKL_01611 0.0 O Type VII secretion system ESX-1, transport TM domain B
DNEJFCKL_01612 1e-169
DNEJFCKL_01613 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DNEJFCKL_01614 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DNEJFCKL_01615 4.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DNEJFCKL_01616 0.0 pacS 3.6.3.54 P E1-E2 ATPase
DNEJFCKL_01617 1.1e-38 csoR S Metal-sensitive transcriptional repressor
DNEJFCKL_01618 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DNEJFCKL_01619 2.3e-246 G Major Facilitator Superfamily
DNEJFCKL_01620 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DNEJFCKL_01621 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DNEJFCKL_01622 2.5e-264 KLT Protein tyrosine kinase
DNEJFCKL_01623 0.0 S Fibronectin type 3 domain
DNEJFCKL_01624 4.5e-226 S ATPase family associated with various cellular activities (AAA)
DNEJFCKL_01625 8.3e-221 S Protein of unknown function DUF58
DNEJFCKL_01626 0.0 E Transglutaminase-like superfamily
DNEJFCKL_01627 4.4e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
DNEJFCKL_01628 1.3e-104 B Belongs to the OprB family
DNEJFCKL_01629 4.1e-101 T Forkhead associated domain
DNEJFCKL_01630 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DNEJFCKL_01631 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DNEJFCKL_01632 8.3e-98
DNEJFCKL_01633 5.6e-180 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DNEJFCKL_01634 4.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DNEJFCKL_01635 7.2e-253 S UPF0210 protein
DNEJFCKL_01636 7.1e-43 gcvR T Belongs to the UPF0237 family
DNEJFCKL_01637 1.1e-23 lmrB EGP Major facilitator Superfamily
DNEJFCKL_01638 3.4e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DNEJFCKL_01639 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DNEJFCKL_01640 3.4e-141 glpR K DeoR C terminal sensor domain
DNEJFCKL_01641 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DNEJFCKL_01642 1.8e-212 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DNEJFCKL_01643 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DNEJFCKL_01644 5.2e-133 glxR K helix_turn_helix, cAMP Regulatory protein
DNEJFCKL_01645 1.2e-200 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DNEJFCKL_01646 2.3e-75 J TM2 domain
DNEJFCKL_01647 1.7e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DNEJFCKL_01648 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DNEJFCKL_01649 1.5e-236 S Uncharacterized conserved protein (DUF2183)
DNEJFCKL_01650 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DNEJFCKL_01651 3.9e-209 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DNEJFCKL_01652 3.4e-160 mhpC I Alpha/beta hydrolase family
DNEJFCKL_01653 3.5e-114 F Domain of unknown function (DUF4916)
DNEJFCKL_01654 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DNEJFCKL_01655 2.3e-168 S G5
DNEJFCKL_01656 4.6e-88
DNEJFCKL_01658 1.6e-262 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DNEJFCKL_01659 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DNEJFCKL_01660 2.5e-147 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01661 1.7e-162 P Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01662 3e-270 G Bacterial extracellular solute-binding protein
DNEJFCKL_01663 1.4e-184 K Psort location Cytoplasmic, score
DNEJFCKL_01664 7e-181 K helix_turn _helix lactose operon repressor
DNEJFCKL_01665 1.8e-223 G Bacterial extracellular solute-binding protein
DNEJFCKL_01666 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
DNEJFCKL_01667 6.6e-145 G Binding-protein-dependent transport system inner membrane component
DNEJFCKL_01668 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
DNEJFCKL_01669 2e-56 yccF S Inner membrane component domain
DNEJFCKL_01670 3.1e-131 S Psort location CytoplasmicMembrane, score 9.99
DNEJFCKL_01671 9.7e-230 S Bacteriophage abortive infection AbiH
DNEJFCKL_01672 2.5e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DNEJFCKL_01673 8.2e-263 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DNEJFCKL_01674 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DNEJFCKL_01675 7.2e-203 cps2J S Polysaccharide biosynthesis protein
DNEJFCKL_01676 3.7e-286 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DNEJFCKL_01677 2.6e-123 IQ Enoyl-(Acyl carrier protein) reductase
DNEJFCKL_01678 2.9e-173 S slime layer polysaccharide biosynthetic process
DNEJFCKL_01679 8.8e-51
DNEJFCKL_01680 3.4e-76 GT2 M Glycosyl transferase, group 2 family protein
DNEJFCKL_01681 3.2e-185 rgpAc GT4 M Domain of unknown function (DUF1972)
DNEJFCKL_01682 3.1e-43 L Transposase
DNEJFCKL_01683 3.3e-36 L Integrase core domain
DNEJFCKL_01684 4.7e-45 L Psort location Cytoplasmic, score 8.87
DNEJFCKL_01685 4.5e-50 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DNEJFCKL_01687 1.8e-104
DNEJFCKL_01688 1.2e-20
DNEJFCKL_01689 1.9e-190 wcoI DM Psort location CytoplasmicMembrane, score
DNEJFCKL_01690 4.6e-223 pflA S Protein of unknown function (DUF4012)
DNEJFCKL_01691 4.1e-86 3.1.3.48 T Low molecular weight phosphatase family
DNEJFCKL_01692 3.8e-182 S Endonuclease/Exonuclease/phosphatase family
DNEJFCKL_01693 2.5e-47
DNEJFCKL_01694 1.4e-284 EGP Major facilitator Superfamily
DNEJFCKL_01695 6.4e-218 T Diguanylate cyclase (GGDEF) domain protein
DNEJFCKL_01696 1.4e-126 L Protein of unknown function (DUF1524)
DNEJFCKL_01697 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DNEJFCKL_01698 1.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
DNEJFCKL_01699 8.9e-198 K helix_turn _helix lactose operon repressor
DNEJFCKL_01700 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DNEJFCKL_01701 6.1e-168 L Escherichia coli O157 H7 ortholog
DNEJFCKL_01702 7.4e-55 L Escherichia coli O157 H7 ortholog
DNEJFCKL_01703 4.2e-29 L DNA integration
DNEJFCKL_01704 2.4e-30 yuxJ EGP Major facilitator Superfamily
DNEJFCKL_01705 1.1e-47 EGP Major facilitator Superfamily
DNEJFCKL_01706 6e-92 EGP Major facilitator Superfamily
DNEJFCKL_01708 4.4e-56
DNEJFCKL_01709 3.3e-295 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DNEJFCKL_01710 3e-10
DNEJFCKL_01711 4.8e-68
DNEJFCKL_01712 1.2e-258 S AAA domain
DNEJFCKL_01713 1.2e-291 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DNEJFCKL_01714 3.4e-161 rfbJ M Glycosyl transferase family 2
DNEJFCKL_01715 6.7e-186 S Psort location CytoplasmicMembrane, score
DNEJFCKL_01716 2.8e-82 S Acyltransferase family
DNEJFCKL_01717 6.1e-109 rgpC U Transport permease protein
DNEJFCKL_01718 1.2e-174 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DNEJFCKL_01719 1.4e-181 M Glycosyl transferases group 1
DNEJFCKL_01720 1.7e-136 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
DNEJFCKL_01721 7.6e-222 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
DNEJFCKL_01722 4.3e-310 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DNEJFCKL_01723 1.4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DNEJFCKL_01724 4.9e-232 S AAA domain
DNEJFCKL_01725 1.2e-61
DNEJFCKL_01726 1.1e-197 K helix_turn _helix lactose operon repressor
DNEJFCKL_01727 2.8e-166 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DNEJFCKL_01728 1.1e-259 EGP Major Facilitator Superfamily
DNEJFCKL_01729 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DNEJFCKL_01730 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DNEJFCKL_01731 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
DNEJFCKL_01732 9.7e-70 ssb1 L Single-stranded DNA-binding protein
DNEJFCKL_01733 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DNEJFCKL_01734 1.7e-70 rplI J Binds to the 23S rRNA
DNEJFCKL_01735 9.3e-161 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DNEJFCKL_01737 5.7e-167 T Pfam Adenylate and Guanylate cyclase catalytic domain
DNEJFCKL_01740 7.6e-12 S zinc-ribbon domain
DNEJFCKL_01741 1.4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DNEJFCKL_01742 8.1e-22 M Protein of unknown function (DUF3152)
DNEJFCKL_01743 3.7e-210 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DNEJFCKL_01744 2.1e-79
DNEJFCKL_01745 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DNEJFCKL_01746 5.8e-174 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DNEJFCKL_01747 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DNEJFCKL_01748 8e-136 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
DNEJFCKL_01749 8.3e-169 rmuC S RmuC family
DNEJFCKL_01750 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DNEJFCKL_01751 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DNEJFCKL_01752 6.2e-134 K Psort location Cytoplasmic, score
DNEJFCKL_01753 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNEJFCKL_01754 8.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DNEJFCKL_01755 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DNEJFCKL_01756 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
DNEJFCKL_01757 2.1e-51 S Protein of unknown function (DUF2469)
DNEJFCKL_01758 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DNEJFCKL_01759 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DNEJFCKL_01760 1.3e-79 K helix_turn_helix ASNC type
DNEJFCKL_01761 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
DNEJFCKL_01762 0.0 S domain protein
DNEJFCKL_01763 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DNEJFCKL_01764 1.6e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
DNEJFCKL_01765 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DNEJFCKL_01766 4.9e-134 KT Transcriptional regulatory protein, C terminal
DNEJFCKL_01767 4.9e-134
DNEJFCKL_01768 9.4e-98 mntP P Probably functions as a manganese efflux pump
DNEJFCKL_01769 9.7e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DNEJFCKL_01770 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DNEJFCKL_01771 7.1e-175 M LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01772 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
DNEJFCKL_01773 3.9e-193 yfdV S Membrane transport protein
DNEJFCKL_01774 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DNEJFCKL_01775 2.4e-82 L Phage integrase family
DNEJFCKL_01776 1.4e-84 3.2.1.20, 3.5.1.28 GH31 V N-acetylmuramoyl-L-alanine amidase
DNEJFCKL_01777 5.3e-28 S Bacteriophage holin family
DNEJFCKL_01778 3.4e-44
DNEJFCKL_01779 7.1e-108
DNEJFCKL_01780 1.2e-154 NT phage tail tape measure protein
DNEJFCKL_01781 6.5e-36
DNEJFCKL_01782 1.9e-54
DNEJFCKL_01783 4.3e-60
DNEJFCKL_01784 5.3e-33
DNEJFCKL_01785 2.8e-41
DNEJFCKL_01786 6.6e-210 S Caudovirus prohead serine protease
DNEJFCKL_01787 4e-161 S Phage portal protein
DNEJFCKL_01788 6.5e-236 S Terminase
DNEJFCKL_01789 1.3e-38
DNEJFCKL_01790 1.8e-98 L HNH endonuclease
DNEJFCKL_01791 4.8e-17 S Helix-turn-helix domain
DNEJFCKL_01792 1.4e-43
DNEJFCKL_01794 3.9e-28
DNEJFCKL_01797 2.7e-18 K BetR domain
DNEJFCKL_01799 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DNEJFCKL_01800 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
DNEJFCKL_01801 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNEJFCKL_01802 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DNEJFCKL_01803 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DNEJFCKL_01804 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DNEJFCKL_01805 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DNEJFCKL_01806 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DNEJFCKL_01807 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DNEJFCKL_01808 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DNEJFCKL_01809 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DNEJFCKL_01810 9.2e-191
DNEJFCKL_01811 1.7e-179
DNEJFCKL_01812 6e-169 trxA2 O Tetratricopeptide repeat
DNEJFCKL_01813 4.7e-122 cyaA 4.6.1.1 S CYTH
DNEJFCKL_01815 7e-60 psp1 3.5.99.10 J Endoribonuclease L-PSP
DNEJFCKL_01816 5.7e-272 mmuP E amino acid
DNEJFCKL_01817 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DNEJFCKL_01818 3.5e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DNEJFCKL_01819 5.5e-242 hom 1.1.1.3 E Homoserine dehydrogenase
DNEJFCKL_01820 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DNEJFCKL_01821 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DNEJFCKL_01822 3.3e-211 K helix_turn _helix lactose operon repressor
DNEJFCKL_01823 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DNEJFCKL_01824 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
DNEJFCKL_01825 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DNEJFCKL_01826 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DNEJFCKL_01827 0.0 cydD V ABC transporter transmembrane region
DNEJFCKL_01828 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DNEJFCKL_01829 2.1e-129 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DNEJFCKL_01830 9.1e-240 G Bacterial extracellular solute-binding protein
DNEJFCKL_01831 2.7e-88 K helix_turn _helix lactose operon repressor
DNEJFCKL_01832 7.5e-109 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01833 1.2e-49 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01834 3.5e-155 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01835 1.8e-32 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01836 1.1e-101 S LPXTG-motif cell wall anchor domain protein
DNEJFCKL_01837 4.3e-68 ugpC E Belongs to the ABC transporter superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)