ORF_ID e_value Gene_name EC_number CAZy COGs Description
GKPIPPIE_00001 1.1e-72 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKPIPPIE_00002 2.9e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKPIPPIE_00003 4.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GKPIPPIE_00004 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GKPIPPIE_00005 3e-92 S Aldo/keto reductase family
GKPIPPIE_00006 4.2e-37 fldA C Flavodoxin
GKPIPPIE_00007 4e-15 P esterase
GKPIPPIE_00009 2e-80 GM NmrA-like family
GKPIPPIE_00010 1.2e-117 EGP Major Facilitator Superfamily
GKPIPPIE_00011 6.6e-127 akr5f 1.1.1.346 S reductase
GKPIPPIE_00012 1.2e-72 K Transcriptional regulator
GKPIPPIE_00013 1.3e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
GKPIPPIE_00014 8.8e-70 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKPIPPIE_00015 2.5e-84 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_00016 3.6e-131 L Belongs to the 'phage' integrase family
GKPIPPIE_00017 1.3e-62 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_00018 4.4e-201 hsdM 2.1.1.72 V type I restriction-modification system
GKPIPPIE_00019 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GKPIPPIE_00021 8.7e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
GKPIPPIE_00022 5.7e-57 3.6.1.27 I Acid phosphatase homologues
GKPIPPIE_00023 1.1e-67 maa 2.3.1.79 S Maltose acetyltransferase
GKPIPPIE_00024 8.2e-73 2.3.1.178 M GNAT acetyltransferase
GKPIPPIE_00026 2.7e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
GKPIPPIE_00027 7.8e-65 ypsA S Belongs to the UPF0398 family
GKPIPPIE_00028 3.7e-188 nhaC C Na H antiporter NhaC
GKPIPPIE_00029 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKPIPPIE_00030 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GKPIPPIE_00031 1.2e-112 xerD D recombinase XerD
GKPIPPIE_00032 1.6e-125 cvfB S S1 domain
GKPIPPIE_00033 4.1e-51 yeaL S Protein of unknown function (DUF441)
GKPIPPIE_00034 2e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKPIPPIE_00035 3.4e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GKPIPPIE_00036 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKPIPPIE_00037 1.6e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKPIPPIE_00038 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKPIPPIE_00039 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKPIPPIE_00040 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKPIPPIE_00041 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
GKPIPPIE_00042 2.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GKPIPPIE_00043 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GKPIPPIE_00045 8.1e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GKPIPPIE_00046 2.9e-27 ysxB J Cysteine protease Prp
GKPIPPIE_00047 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
GKPIPPIE_00050 2.2e-08 S Protein of unknown function (DUF2922)
GKPIPPIE_00052 1.3e-16 K DNA-templated transcription, initiation
GKPIPPIE_00054 8.6e-67 H Methyltransferase domain
GKPIPPIE_00055 1.7e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
GKPIPPIE_00056 1.3e-40 wecD M Acetyltransferase (GNAT) family
GKPIPPIE_00058 3.6e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GKPIPPIE_00059 1.3e-41 S Protein of unknown function (DUF1211)
GKPIPPIE_00061 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
GKPIPPIE_00062 8.3e-85 L Restriction endonuclease
GKPIPPIE_00063 1.4e-83 1.1.1.1 C Zinc-binding dehydrogenase
GKPIPPIE_00064 1.1e-31 S CHY zinc finger
GKPIPPIE_00065 9.5e-40 K Transcriptional regulator
GKPIPPIE_00066 2e-83 qorB 1.6.5.2 GM NmrA-like family
GKPIPPIE_00068 2.2e-63 M Glycosyl transferases group 1
GKPIPPIE_00069 1.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKPIPPIE_00070 2.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
GKPIPPIE_00071 8.2e-104 cps2I S Psort location CytoplasmicMembrane, score
GKPIPPIE_00072 4.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
GKPIPPIE_00073 6.8e-116 S Glycosyltransferase WbsX
GKPIPPIE_00074 6.1e-117 S Glycosyltransferase WbsX
GKPIPPIE_00075 4.1e-53
GKPIPPIE_00077 1.8e-58 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
GKPIPPIE_00078 2.3e-42 GT2 V Glycosyl transferase, family 2
GKPIPPIE_00079 3e-71 M Glycosyltransferase Family 4
GKPIPPIE_00080 7.6e-78 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
GKPIPPIE_00081 2.3e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
GKPIPPIE_00082 6e-125 2.4.1.52 GT4 M Glycosyl transferases group 1
GKPIPPIE_00083 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
GKPIPPIE_00084 2.8e-77 epsL M Bacterial sugar transferase
GKPIPPIE_00085 6.9e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
GKPIPPIE_00086 3.6e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
GKPIPPIE_00087 7.2e-65 cpsD D AAA domain
GKPIPPIE_00088 6.9e-48 cps4C M Chain length determinant protein
GKPIPPIE_00089 1e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
GKPIPPIE_00090 8.5e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GKPIPPIE_00091 8.1e-81
GKPIPPIE_00092 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GKPIPPIE_00093 1.8e-113 yitU 3.1.3.104 S hydrolase
GKPIPPIE_00094 2.6e-60 speG J Acetyltransferase (GNAT) domain
GKPIPPIE_00095 6.3e-190 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKPIPPIE_00096 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GKPIPPIE_00097 7.1e-203 pipD E Dipeptidase
GKPIPPIE_00098 3.3e-44
GKPIPPIE_00099 2.6e-64 K helix_turn_helix, arabinose operon control protein
GKPIPPIE_00100 3.4e-53 S Membrane
GKPIPPIE_00101 4.2e-98 rafA 3.2.1.22 G alpha-galactosidase
GKPIPPIE_00102 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_00103 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_00104 8.3e-80 rafA 3.2.1.22 G alpha-galactosidase
GKPIPPIE_00105 1.7e-119 rafA 3.2.1.22 G alpha-galactosidase
GKPIPPIE_00107 2.3e-59 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
GKPIPPIE_00108 6.8e-212 L Helicase C-terminal domain protein
GKPIPPIE_00109 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
GKPIPPIE_00110 3.4e-95 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
GKPIPPIE_00111 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
GKPIPPIE_00112 1.4e-113 2.7.7.65 T diguanylate cyclase activity
GKPIPPIE_00113 0.0 ydaN S Bacterial cellulose synthase subunit
GKPIPPIE_00114 1.2e-201 ydaM M Glycosyl transferase family group 2
GKPIPPIE_00115 5.5e-204 S Protein conserved in bacteria
GKPIPPIE_00116 3.2e-182
GKPIPPIE_00117 2.5e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
GKPIPPIE_00118 2.1e-43 2.7.7.65 T GGDEF domain
GKPIPPIE_00119 1.6e-145 pbuO_1 S Permease family
GKPIPPIE_00120 4.2e-156 ndh 1.6.99.3 C NADH dehydrogenase
GKPIPPIE_00121 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GKPIPPIE_00122 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GKPIPPIE_00123 6.7e-219 cydD CO ABC transporter transmembrane region
GKPIPPIE_00124 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKPIPPIE_00125 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GKPIPPIE_00126 4.3e-192 cydA 1.10.3.14 C ubiquinol oxidase
GKPIPPIE_00127 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
GKPIPPIE_00128 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
GKPIPPIE_00129 5e-19 glpE P Rhodanese Homology Domain
GKPIPPIE_00130 1.6e-48 lytE M LysM domain protein
GKPIPPIE_00131 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
GKPIPPIE_00132 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
GKPIPPIE_00134 3.3e-74 draG O ADP-ribosylglycohydrolase
GKPIPPIE_00135 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKPIPPIE_00136 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKPIPPIE_00137 8.6e-62 divIVA D DivIVA domain protein
GKPIPPIE_00138 1.7e-81 ylmH S S4 domain protein
GKPIPPIE_00139 3e-19 yggT S YGGT family
GKPIPPIE_00140 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKPIPPIE_00141 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKPIPPIE_00142 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKPIPPIE_00143 1.6e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKPIPPIE_00144 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKPIPPIE_00145 4.5e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKPIPPIE_00146 2.5e-135 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKPIPPIE_00147 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
GKPIPPIE_00148 2.5e-11 ftsL D cell division protein FtsL
GKPIPPIE_00149 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKPIPPIE_00150 5.2e-64 mraZ K Belongs to the MraZ family
GKPIPPIE_00151 4.5e-08 S Protein of unknown function (DUF3397)
GKPIPPIE_00152 1.6e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
GKPIPPIE_00154 6.3e-99 D Alpha beta
GKPIPPIE_00155 1.8e-108 aatB ET ABC transporter substrate-binding protein
GKPIPPIE_00156 8.2e-90 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GKPIPPIE_00157 1.9e-94 glnP P ABC transporter permease
GKPIPPIE_00158 1.8e-126 minD D Belongs to the ParA family
GKPIPPIE_00159 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GKPIPPIE_00160 3.4e-54 mreD M rod shape-determining protein MreD
GKPIPPIE_00161 2.1e-88 mreC M Involved in formation and maintenance of cell shape
GKPIPPIE_00162 3.6e-156 mreB D cell shape determining protein MreB
GKPIPPIE_00163 4.5e-21 K Cold shock
GKPIPPIE_00164 1.4e-79 radC L DNA repair protein
GKPIPPIE_00165 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GKPIPPIE_00166 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKPIPPIE_00167 5.5e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKPIPPIE_00168 1.7e-162 iscS2 2.8.1.7 E Aminotransferase class V
GKPIPPIE_00169 3.8e-174 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKPIPPIE_00170 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
GKPIPPIE_00171 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKPIPPIE_00172 3.4e-24 yueI S Protein of unknown function (DUF1694)
GKPIPPIE_00173 5.2e-189 rarA L recombination factor protein RarA
GKPIPPIE_00175 3.2e-73 usp6 T universal stress protein
GKPIPPIE_00176 3.8e-54 tag 3.2.2.20 L glycosylase
GKPIPPIE_00177 8.5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GKPIPPIE_00178 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GKPIPPIE_00181 6.9e-73 yviA S Protein of unknown function (DUF421)
GKPIPPIE_00182 1.8e-27 S Protein of unknown function (DUF3290)
GKPIPPIE_00183 6.8e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
GKPIPPIE_00184 2.1e-296 S membrane
GKPIPPIE_00185 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKPIPPIE_00186 1.1e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
GKPIPPIE_00187 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
GKPIPPIE_00188 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKPIPPIE_00190 2.4e-16
GKPIPPIE_00191 1.3e-199 oatA I Acyltransferase
GKPIPPIE_00192 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKPIPPIE_00193 3.3e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKPIPPIE_00194 2.6e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKPIPPIE_00197 6.2e-16 S Phosphoesterase
GKPIPPIE_00198 9.5e-21 S Calcineurin-like phosphoesterase superfamily domain
GKPIPPIE_00199 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKPIPPIE_00200 1.1e-60 yslB S Protein of unknown function (DUF2507)
GKPIPPIE_00201 9.9e-41 trxA O Belongs to the thioredoxin family
GKPIPPIE_00202 9.4e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKPIPPIE_00203 1.6e-17 cvpA S Colicin V production protein
GKPIPPIE_00204 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GKPIPPIE_00205 1.9e-33 yrzB S Belongs to the UPF0473 family
GKPIPPIE_00206 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKPIPPIE_00207 2.1e-36 yrzL S Belongs to the UPF0297 family
GKPIPPIE_00208 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKPIPPIE_00209 1.1e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKPIPPIE_00210 4.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GKPIPPIE_00211 7.5e-13
GKPIPPIE_00212 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKPIPPIE_00213 1.6e-65 yrjD S LUD domain
GKPIPPIE_00214 1.8e-244 lutB C 4Fe-4S dicluster domain
GKPIPPIE_00215 6.9e-117 lutA C Cysteine-rich domain
GKPIPPIE_00216 2e-208 yfnA E Amino Acid
GKPIPPIE_00218 4.3e-61 uspA T universal stress protein
GKPIPPIE_00220 1.4e-12 yajC U Preprotein translocase
GKPIPPIE_00221 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKPIPPIE_00222 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKPIPPIE_00223 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKPIPPIE_00224 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKPIPPIE_00225 1.3e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKPIPPIE_00226 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKPIPPIE_00227 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
GKPIPPIE_00228 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKPIPPIE_00229 4.7e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKPIPPIE_00230 5.9e-65 ymfM S Helix-turn-helix domain
GKPIPPIE_00231 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
GKPIPPIE_00232 5.4e-149 ymfH S Peptidase M16
GKPIPPIE_00233 1.4e-109 ymfF S Peptidase M16 inactive domain protein
GKPIPPIE_00234 1.1e-282 ftsK D Belongs to the FtsK SpoIIIE SftA family
GKPIPPIE_00235 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKPIPPIE_00236 3.4e-99 rrmA 2.1.1.187 H Methyltransferase
GKPIPPIE_00237 1.3e-64 ybaK J Aminoacyl-tRNA editing domain
GKPIPPIE_00238 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKPIPPIE_00239 6.2e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKPIPPIE_00240 1.4e-21 cutC P Participates in the control of copper homeostasis
GKPIPPIE_00241 4.4e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GKPIPPIE_00242 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GKPIPPIE_00243 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKPIPPIE_00244 1.6e-65 ybbR S YbbR-like protein
GKPIPPIE_00245 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKPIPPIE_00246 1.8e-71 S Protein of unknown function (DUF1361)
GKPIPPIE_00247 1.2e-115 murB 1.3.1.98 M Cell wall formation
GKPIPPIE_00248 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
GKPIPPIE_00249 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GKPIPPIE_00250 2.2e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GKPIPPIE_00251 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKPIPPIE_00252 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
GKPIPPIE_00253 4.1e-42 yxjI
GKPIPPIE_00254 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKPIPPIE_00255 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKPIPPIE_00256 2.8e-19 secG U Preprotein translocase
GKPIPPIE_00257 4.6e-179 clcA P chloride
GKPIPPIE_00258 9e-151 lmrP E Major Facilitator Superfamily
GKPIPPIE_00259 3.1e-169 T PhoQ Sensor
GKPIPPIE_00260 1.9e-103 K response regulator
GKPIPPIE_00261 6.5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKPIPPIE_00262 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKPIPPIE_00263 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKPIPPIE_00264 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GKPIPPIE_00265 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKPIPPIE_00266 2.9e-137 cggR K Putative sugar-binding domain
GKPIPPIE_00268 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKPIPPIE_00269 1.8e-149 whiA K May be required for sporulation
GKPIPPIE_00270 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GKPIPPIE_00271 5.7e-126 rapZ S Displays ATPase and GTPase activities
GKPIPPIE_00272 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
GKPIPPIE_00273 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKPIPPIE_00274 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKPIPPIE_00275 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKPIPPIE_00276 5.2e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKPIPPIE_00277 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKPIPPIE_00278 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKPIPPIE_00279 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GKPIPPIE_00280 4.1e-08 KT PspC domain protein
GKPIPPIE_00281 1.5e-55 phoR 2.7.13.3 T Histidine kinase
GKPIPPIE_00282 3.5e-86 K response regulator
GKPIPPIE_00283 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
GKPIPPIE_00284 1.1e-72 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKPIPPIE_00285 6.2e-62 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKPIPPIE_00286 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKPIPPIE_00287 6.2e-90 yeaN P Major Facilitator Superfamily
GKPIPPIE_00288 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKPIPPIE_00289 1e-45 comFC S Competence protein
GKPIPPIE_00290 5.4e-128 comFA L Helicase C-terminal domain protein
GKPIPPIE_00291 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
GKPIPPIE_00292 4.1e-296 ydaO E amino acid
GKPIPPIE_00293 9.7e-269 aha1 P COG COG0474 Cation transport ATPase
GKPIPPIE_00294 4.8e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKPIPPIE_00295 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKPIPPIE_00296 5.3e-33 S CAAX protease self-immunity
GKPIPPIE_00297 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKPIPPIE_00298 5.5e-254 uup S ABC transporter, ATP-binding protein
GKPIPPIE_00299 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKPIPPIE_00300 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GKPIPPIE_00301 4.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GKPIPPIE_00302 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
GKPIPPIE_00303 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
GKPIPPIE_00304 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKPIPPIE_00305 1.4e-40 yabA L Involved in initiation control of chromosome replication
GKPIPPIE_00306 1e-83 holB 2.7.7.7 L DNA polymerase III
GKPIPPIE_00307 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKPIPPIE_00308 9.2e-29 yaaL S Protein of unknown function (DUF2508)
GKPIPPIE_00309 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKPIPPIE_00310 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKPIPPIE_00311 1.1e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKPIPPIE_00312 4.8e-61 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKPIPPIE_00313 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
GKPIPPIE_00314 1.2e-27 nrdH O Glutaredoxin
GKPIPPIE_00315 4.8e-45 nrdI F NrdI Flavodoxin like
GKPIPPIE_00316 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKPIPPIE_00317 1.4e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKPIPPIE_00318 7.9e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKPIPPIE_00319 1.4e-54
GKPIPPIE_00320 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKPIPPIE_00321 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKPIPPIE_00322 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKPIPPIE_00323 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKPIPPIE_00324 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
GKPIPPIE_00325 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKPIPPIE_00326 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GKPIPPIE_00327 7e-71 yacP S YacP-like NYN domain
GKPIPPIE_00328 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKPIPPIE_00329 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKPIPPIE_00330 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GKPIPPIE_00331 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKPIPPIE_00332 8.2e-154 yacL S domain protein
GKPIPPIE_00333 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKPIPPIE_00334 3.1e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GKPIPPIE_00335 1.6e-18 HA62_12640 S GCN5-related N-acetyl-transferase
GKPIPPIE_00336 8.4e-222 pepC 3.4.22.40 E Peptidase C1-like family
GKPIPPIE_00337 1e-33 S Enterocin A Immunity
GKPIPPIE_00338 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKPIPPIE_00339 4.5e-129 mleP2 S Sodium Bile acid symporter family
GKPIPPIE_00340 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKPIPPIE_00342 2.3e-43 ydcK S Belongs to the SprT family
GKPIPPIE_00343 1.3e-251 yhgF K Tex-like protein N-terminal domain protein
GKPIPPIE_00344 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKPIPPIE_00345 1.6e-242 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKPIPPIE_00346 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKPIPPIE_00347 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
GKPIPPIE_00348 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKPIPPIE_00350 1.1e-07
GKPIPPIE_00351 1.6e-197 dtpT U amino acid peptide transporter
GKPIPPIE_00353 3.8e-93 yihY S Belongs to the UPF0761 family
GKPIPPIE_00354 4.7e-12 mltD CBM50 M Lysin motif
GKPIPPIE_00355 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GKPIPPIE_00356 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
GKPIPPIE_00357 5.1e-54 fld C Flavodoxin
GKPIPPIE_00358 5.1e-53 gtcA S Teichoic acid glycosylation protein
GKPIPPIE_00359 0.0 S Bacterial membrane protein YfhO
GKPIPPIE_00360 3.4e-119 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GKPIPPIE_00361 3.8e-122 S Sulfite exporter TauE/SafE
GKPIPPIE_00362 1.1e-70 K Sugar-specific transcriptional regulator TrmB
GKPIPPIE_00363 3.2e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKPIPPIE_00364 3.5e-182 pepS E Thermophilic metalloprotease (M29)
GKPIPPIE_00365 3e-266 E Amino acid permease
GKPIPPIE_00366 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GKPIPPIE_00367 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GKPIPPIE_00368 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
GKPIPPIE_00369 4.3e-213 malT G Transporter, major facilitator family protein
GKPIPPIE_00370 9.4e-101 malR K Transcriptional regulator, LacI family
GKPIPPIE_00371 3.9e-279 kup P Transport of potassium into the cell
GKPIPPIE_00373 1.5e-20 S Domain of unknown function (DUF3284)
GKPIPPIE_00374 1.1e-159 yfmL L DEAD DEAH box helicase
GKPIPPIE_00375 5.4e-128 mocA S Oxidoreductase
GKPIPPIE_00376 2e-24 S Domain of unknown function (DUF4828)
GKPIPPIE_00377 1.8e-174 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
GKPIPPIE_00378 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GKPIPPIE_00379 8.8e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
GKPIPPIE_00380 6.2e-54 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GKPIPPIE_00381 9.7e-56 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GKPIPPIE_00382 6e-160 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GKPIPPIE_00383 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKPIPPIE_00384 3.3e-218 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GKPIPPIE_00385 8.3e-39 O ADP-ribosylglycohydrolase
GKPIPPIE_00386 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
GKPIPPIE_00387 2.2e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GKPIPPIE_00388 1.1e-33 K GNAT family
GKPIPPIE_00389 1.7e-40
GKPIPPIE_00391 1.6e-159 mgtE P Acts as a magnesium transporter
GKPIPPIE_00392 1.9e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GKPIPPIE_00393 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKPIPPIE_00394 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
GKPIPPIE_00395 2.5e-257 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GKPIPPIE_00396 1.3e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
GKPIPPIE_00397 9.7e-194 pbuX F xanthine permease
GKPIPPIE_00398 2.8e-73 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKPIPPIE_00399 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
GKPIPPIE_00400 3.2e-64 S ECF transporter, substrate-specific component
GKPIPPIE_00401 4.3e-127 mleP S Sodium Bile acid symporter family
GKPIPPIE_00402 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GKPIPPIE_00403 1.8e-71 mleR K LysR family
GKPIPPIE_00404 1.1e-56 K transcriptional
GKPIPPIE_00405 7.6e-41 K Bacterial regulatory proteins, tetR family
GKPIPPIE_00406 6.1e-60 T Belongs to the universal stress protein A family
GKPIPPIE_00407 1.2e-44 K Copper transport repressor CopY TcrY
GKPIPPIE_00408 1.8e-214 3.2.1.18 GH33 M Rib/alpha-like repeat
GKPIPPIE_00410 6.5e-96 ypuA S Protein of unknown function (DUF1002)
GKPIPPIE_00411 1.2e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
GKPIPPIE_00412 1.3e-186 UW LPXTG-motif cell wall anchor domain protein
GKPIPPIE_00413 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKPIPPIE_00414 2e-17 yncA 2.3.1.79 S Maltose acetyltransferase
GKPIPPIE_00415 2e-205 yflS P Sodium:sulfate symporter transmembrane region
GKPIPPIE_00416 1.2e-199 frdC 1.3.5.4 C FAD binding domain
GKPIPPIE_00417 1.5e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKPIPPIE_00418 2e-14 ybaN S Protein of unknown function (DUF454)
GKPIPPIE_00419 1e-179 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GKPIPPIE_00420 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKPIPPIE_00421 9.6e-97 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKPIPPIE_00422 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GKPIPPIE_00423 6.7e-72 ywlG S Belongs to the UPF0340 family
GKPIPPIE_00424 5.5e-15 S Acetyltransferase (GNAT) domain
GKPIPPIE_00425 5.7e-45 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKPIPPIE_00426 1e-24 yjaB_1 K Psort location Cytoplasmic, score 8.87
GKPIPPIE_00427 1e-10 Z012_01675 S X-Pro dipeptidyl-peptidase (S15 family)
GKPIPPIE_00428 7.9e-50 K Cro/C1-type HTH DNA-binding domain
GKPIPPIE_00429 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
GKPIPPIE_00430 1.5e-40
GKPIPPIE_00431 3.7e-97
GKPIPPIE_00432 1.1e-101 S Domain of unknown function (DUF4343)
GKPIPPIE_00433 0.0 L helicase activity
GKPIPPIE_00434 6.5e-187 K DNA binding
GKPIPPIE_00435 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
GKPIPPIE_00436 3e-236 mod 2.1.1.72, 3.1.21.5 L DNA methylase
GKPIPPIE_00437 3.1e-236 S Protein of unknown function DUF262
GKPIPPIE_00438 2.4e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKPIPPIE_00439 9.8e-146 yegS 2.7.1.107 G Lipid kinase
GKPIPPIE_00440 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKPIPPIE_00441 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKPIPPIE_00442 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKPIPPIE_00443 7.1e-161 camS S sex pheromone
GKPIPPIE_00444 5.1e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKPIPPIE_00445 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GKPIPPIE_00446 3.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKPIPPIE_00450 1.1e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GKPIPPIE_00451 4.7e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKPIPPIE_00452 1.1e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKPIPPIE_00453 4.7e-280 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKPIPPIE_00454 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GKPIPPIE_00455 5.5e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKPIPPIE_00456 1.1e-40 yabR J RNA binding
GKPIPPIE_00457 1e-21 divIC D Septum formation initiator
GKPIPPIE_00458 3.6e-31 yabO J S4 domain protein
GKPIPPIE_00459 1.5e-140 yabM S Polysaccharide biosynthesis protein
GKPIPPIE_00460 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKPIPPIE_00461 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKPIPPIE_00462 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GKPIPPIE_00463 1.5e-25 V Restriction endonuclease
GKPIPPIE_00465 7.1e-86 S (CBS) domain
GKPIPPIE_00466 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKPIPPIE_00467 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKPIPPIE_00468 7.2e-53 perR P Belongs to the Fur family
GKPIPPIE_00469 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
GKPIPPIE_00470 9.4e-99 sbcC L Putative exonuclease SbcCD, C subunit
GKPIPPIE_00471 1.4e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GKPIPPIE_00472 2.1e-36 M LysM domain protein
GKPIPPIE_00473 2.8e-276 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GKPIPPIE_00474 1.6e-84 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GKPIPPIE_00475 2e-35 ygfC K Bacterial regulatory proteins, tetR family
GKPIPPIE_00476 2.2e-100 hrtB V ABC transporter permease
GKPIPPIE_00477 1.5e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GKPIPPIE_00478 4.7e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GKPIPPIE_00479 0.0 helD 3.6.4.12 L DNA helicase
GKPIPPIE_00480 8.9e-246 yjbQ P TrkA C-terminal domain protein
GKPIPPIE_00481 3.4e-23
GKPIPPIE_00482 1.2e-59 rpsI J Belongs to the universal ribosomal protein uS9 family
GKPIPPIE_00483 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKPIPPIE_00484 1.2e-124 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKPIPPIE_00485 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKPIPPIE_00486 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKPIPPIE_00487 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKPIPPIE_00488 4.8e-53 rplQ J Ribosomal protein L17
GKPIPPIE_00489 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKPIPPIE_00490 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKPIPPIE_00491 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKPIPPIE_00492 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GKPIPPIE_00493 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKPIPPIE_00494 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKPIPPIE_00495 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKPIPPIE_00496 1e-67 rplO J Binds to the 23S rRNA
GKPIPPIE_00497 2.1e-22 rpmD J Ribosomal protein L30
GKPIPPIE_00498 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKPIPPIE_00499 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKPIPPIE_00500 1.2e-86 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKPIPPIE_00501 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKPIPPIE_00502 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKPIPPIE_00503 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKPIPPIE_00504 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKPIPPIE_00505 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKPIPPIE_00506 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKPIPPIE_00507 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
GKPIPPIE_00508 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKPIPPIE_00509 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKPIPPIE_00510 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKPIPPIE_00511 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKPIPPIE_00512 2.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKPIPPIE_00513 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKPIPPIE_00514 1e-100 rplD J Forms part of the polypeptide exit tunnel
GKPIPPIE_00515 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKPIPPIE_00516 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GKPIPPIE_00517 3.6e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKPIPPIE_00518 2.5e-78 K rpiR family
GKPIPPIE_00519 5.9e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GKPIPPIE_00520 1.1e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
GKPIPPIE_00521 6.5e-21 K Acetyltransferase (GNAT) domain
GKPIPPIE_00522 8.4e-182 steT E amino acid
GKPIPPIE_00523 9.6e-78 glnP P ABC transporter permease
GKPIPPIE_00524 1.2e-85 gluC P ABC transporter permease
GKPIPPIE_00525 6.6e-100 glnH ET ABC transporter
GKPIPPIE_00526 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GKPIPPIE_00527 3.9e-08
GKPIPPIE_00528 2.2e-98
GKPIPPIE_00530 3.2e-53 zur P Belongs to the Fur family
GKPIPPIE_00531 2.2e-212 yfnA E Amino Acid
GKPIPPIE_00532 6.2e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKPIPPIE_00533 0.0 L Helicase C-terminal domain protein
GKPIPPIE_00534 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
GKPIPPIE_00535 2.1e-180 yhdP S Transporter associated domain
GKPIPPIE_00536 1.7e-26
GKPIPPIE_00537 5.3e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GKPIPPIE_00538 3.7e-131 bacI V MacB-like periplasmic core domain
GKPIPPIE_00539 7.4e-97 V ABC transporter
GKPIPPIE_00540 2.6e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKPIPPIE_00541 8.9e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
GKPIPPIE_00542 6.2e-140 V MatE
GKPIPPIE_00543 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKPIPPIE_00544 4.2e-86 S Alpha beta hydrolase
GKPIPPIE_00545 7.1e-95 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKPIPPIE_00546 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKPIPPIE_00547 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
GKPIPPIE_00548 8.4e-102 IQ Enoyl-(Acyl carrier protein) reductase
GKPIPPIE_00549 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
GKPIPPIE_00550 9.6e-54 queT S QueT transporter
GKPIPPIE_00552 1.9e-65 degV S Uncharacterised protein, DegV family COG1307
GKPIPPIE_00553 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKPIPPIE_00554 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKPIPPIE_00555 3.2e-34 trxA O Belongs to the thioredoxin family
GKPIPPIE_00556 1.4e-86 S Sucrose-6F-phosphate phosphohydrolase
GKPIPPIE_00557 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GKPIPPIE_00558 2.8e-49 S Threonine/Serine exporter, ThrE
GKPIPPIE_00559 4.3e-82 thrE S Putative threonine/serine exporter
GKPIPPIE_00560 3.1e-27 cspC K Cold shock protein
GKPIPPIE_00561 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
GKPIPPIE_00562 3.8e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GKPIPPIE_00563 5.4e-23
GKPIPPIE_00564 1.2e-58 3.6.1.27 I phosphatase
GKPIPPIE_00565 1.2e-24
GKPIPPIE_00566 4.7e-66 I alpha/beta hydrolase fold
GKPIPPIE_00567 1.3e-38 azlD S branched-chain amino acid
GKPIPPIE_00568 1.9e-104 azlC E AzlC protein
GKPIPPIE_00569 3.5e-17
GKPIPPIE_00570 1.7e-119 xth 3.1.11.2 L exodeoxyribonuclease III
GKPIPPIE_00571 1.9e-98 V domain protein
GKPIPPIE_00572 7.2e-18
GKPIPPIE_00576 1.1e-09 S zinc-ribbon domain
GKPIPPIE_00577 1.8e-11 S Mor transcription activator family
GKPIPPIE_00578 1.7e-59 yfjR K WYL domain
GKPIPPIE_00579 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKPIPPIE_00580 7.6e-174 malY 4.4.1.8 E Aminotransferase, class I
GKPIPPIE_00581 1.2e-117 K AI-2E family transporter
GKPIPPIE_00582 4e-61 EG EamA-like transporter family
GKPIPPIE_00583 2.3e-76 L haloacid dehalogenase-like hydrolase
GKPIPPIE_00584 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GKPIPPIE_00585 5e-67 1.5.1.38 S NADPH-dependent FMN reductase
GKPIPPIE_00586 1.1e-163 C Luciferase-like monooxygenase
GKPIPPIE_00587 1.8e-40 K Transcriptional regulator, HxlR family
GKPIPPIE_00588 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GKPIPPIE_00589 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
GKPIPPIE_00590 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GKPIPPIE_00591 2.4e-82 pncA Q isochorismatase
GKPIPPIE_00592 3.5e-63 3.1.3.73 G phosphoglycerate mutase
GKPIPPIE_00593 4.1e-254 treB G phosphotransferase system
GKPIPPIE_00594 5.7e-84 treR K UTRA
GKPIPPIE_00595 3.3e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GKPIPPIE_00596 8.4e-168 mdtG EGP Major facilitator Superfamily
GKPIPPIE_00598 1.5e-185 XK27_08315 M Sulfatase
GKPIPPIE_00600 9.6e-56 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GKPIPPIE_00601 6.6e-08 ganB 3.2.1.89 G arabinogalactan
GKPIPPIE_00602 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKPIPPIE_00603 4e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GKPIPPIE_00604 3.4e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKPIPPIE_00605 1.9e-177 thrC 4.2.3.1 E Threonine synthase
GKPIPPIE_00606 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKPIPPIE_00607 1.1e-61 S Psort location CytoplasmicMembrane, score
GKPIPPIE_00608 1.3e-87 waaB GT4 M Glycosyl transferases group 1
GKPIPPIE_00609 6.2e-59 cps3F
GKPIPPIE_00610 5.3e-70 M Domain of unknown function (DUF4422)
GKPIPPIE_00611 1.3e-161 XK27_08315 M Sulfatase
GKPIPPIE_00612 8e-128 S Bacterial membrane protein YfhO
GKPIPPIE_00613 3.6e-14
GKPIPPIE_00614 3.1e-54 cps3I G Acyltransferase family
GKPIPPIE_00615 1.1e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GKPIPPIE_00616 4.4e-39 2.7.7.65 T phosphorelay sensor kinase activity
GKPIPPIE_00617 1.1e-157 XK27_09615 S reductase
GKPIPPIE_00618 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
GKPIPPIE_00619 6.2e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GKPIPPIE_00620 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKPIPPIE_00621 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKPIPPIE_00622 7.1e-79 G Peptidase_C39 like family
GKPIPPIE_00623 3.2e-45 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKPIPPIE_00624 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_00625 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_00627 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GKPIPPIE_00628 7.8e-134 coaA 2.7.1.33 F Pantothenic acid kinase
GKPIPPIE_00629 4.1e-43 E lipolytic protein G-D-S-L family
GKPIPPIE_00630 3.9e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GKPIPPIE_00631 5.6e-190 glnPH2 P ABC transporter permease
GKPIPPIE_00632 3.3e-198 yjeM E Amino Acid
GKPIPPIE_00633 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
GKPIPPIE_00634 8.7e-138 tetA EGP Major facilitator Superfamily
GKPIPPIE_00636 2.8e-68 rny D Peptidase family M23
GKPIPPIE_00637 6.5e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
GKPIPPIE_00638 2.1e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
GKPIPPIE_00639 1.7e-117 M Core-2/I-Branching enzyme
GKPIPPIE_00640 2.6e-91 rfbP M Bacterial sugar transferase
GKPIPPIE_00641 7e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GKPIPPIE_00642 4.6e-111 ywqE 3.1.3.48 GM PHP domain protein
GKPIPPIE_00643 2.7e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GKPIPPIE_00644 8.4e-76 epsB M biosynthesis protein
GKPIPPIE_00645 4.2e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
GKPIPPIE_00646 4.3e-67 licD2 M LicD family
GKPIPPIE_00647 1.3e-67 porS S Polysaccharide biosynthesis protein
GKPIPPIE_00648 1.2e-70 MA20_17390 GT4 M Glycosyl transferases group 1
GKPIPPIE_00650 1.2e-41 MA20_43635 M Capsular polysaccharide synthesis protein
GKPIPPIE_00651 3.2e-49 M Glycosyltransferase
GKPIPPIE_00652 5.8e-32 epsJ S COG COG0463 Glycosyltransferases involved in cell wall biogenesis
GKPIPPIE_00653 1.6e-106 M PFAM Glycosyl transferase, group 1
GKPIPPIE_00654 5.9e-114 3.6.4.12 L UvrD/REP helicase N-terminal domain
GKPIPPIE_00655 4.8e-144 L AAA ATPase domain
GKPIPPIE_00656 4.9e-79 S response to antibiotic
GKPIPPIE_00657 9.8e-27 S zinc-ribbon domain
GKPIPPIE_00658 2.1e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
GKPIPPIE_00659 2.1e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKPIPPIE_00660 3.1e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKPIPPIE_00661 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GKPIPPIE_00662 5.1e-143 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKPIPPIE_00663 1.1e-61 S Glycosyltransferase like family 2
GKPIPPIE_00664 1.3e-116 cps1D M Domain of unknown function (DUF4422)
GKPIPPIE_00665 1.1e-38 S CAAX protease self-immunity
GKPIPPIE_00666 9.1e-89 yvyE 3.4.13.9 S YigZ family
GKPIPPIE_00667 2.9e-58 S Haloacid dehalogenase-like hydrolase
GKPIPPIE_00668 5.8e-154 EGP Major facilitator Superfamily
GKPIPPIE_00670 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GKPIPPIE_00671 1e-26 adhR K helix_turn_helix, mercury resistance
GKPIPPIE_00672 2.3e-89 S NADPH-dependent FMN reductase
GKPIPPIE_00673 3.4e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GKPIPPIE_00674 1.5e-55 S ECF transporter, substrate-specific component
GKPIPPIE_00675 2.8e-95 znuB U ABC 3 transport family
GKPIPPIE_00676 7e-100 fhuC P ABC transporter
GKPIPPIE_00677 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
GKPIPPIE_00678 1.3e-40
GKPIPPIE_00679 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_00680 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_00681 5e-51 I Alpha/beta hydrolase family
GKPIPPIE_00682 1.4e-94 S Bacterial membrane protein, YfhO
GKPIPPIE_00683 5.5e-53 XK27_01040 S Protein of unknown function (DUF1129)
GKPIPPIE_00684 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKPIPPIE_00685 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
GKPIPPIE_00686 1.2e-107 spo0J K Belongs to the ParB family
GKPIPPIE_00687 6.5e-118 soj D Sporulation initiation inhibitor
GKPIPPIE_00688 3.7e-82 noc K Belongs to the ParB family
GKPIPPIE_00689 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GKPIPPIE_00690 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GKPIPPIE_00691 5.8e-111 3.1.4.46 C phosphodiesterase
GKPIPPIE_00692 0.0 pacL 3.6.3.8 P P-type ATPase
GKPIPPIE_00693 2.3e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
GKPIPPIE_00694 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_00695 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_00696 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GKPIPPIE_00698 4e-63 srtA 3.4.22.70 M sortase family
GKPIPPIE_00699 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GKPIPPIE_00700 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKPIPPIE_00701 9.6e-35
GKPIPPIE_00702 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKPIPPIE_00703 4.4e-156 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKPIPPIE_00704 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKPIPPIE_00705 2.4e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
GKPIPPIE_00706 1.1e-39 ybjQ S Belongs to the UPF0145 family
GKPIPPIE_00707 8.2e-07
GKPIPPIE_00708 1.4e-95 V ABC transporter, ATP-binding protein
GKPIPPIE_00709 1.1e-41 gntR1 K Transcriptional regulator, GntR family
GKPIPPIE_00710 1.7e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
GKPIPPIE_00711 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKPIPPIE_00712 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
GKPIPPIE_00713 1.1e-106 terC P Integral membrane protein TerC family
GKPIPPIE_00714 1.6e-38 K Transcriptional regulator
GKPIPPIE_00715 8.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GKPIPPIE_00716 3.2e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GKPIPPIE_00717 4.5e-102 tcyB E ABC transporter
GKPIPPIE_00719 2e-18 ganB 3.2.1.89 G arabinogalactan
GKPIPPIE_00720 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GKPIPPIE_00721 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKPIPPIE_00722 3.4e-209 mtlR K Mga helix-turn-helix domain
GKPIPPIE_00723 1.1e-175 yjcE P Sodium proton antiporter
GKPIPPIE_00724 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GKPIPPIE_00725 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
GKPIPPIE_00726 2.8e-68 dhaL 2.7.1.121 S Dak2
GKPIPPIE_00727 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GKPIPPIE_00728 4.2e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GKPIPPIE_00729 1.7e-61 K Bacterial regulatory proteins, tetR family
GKPIPPIE_00730 6.5e-209 brnQ U Component of the transport system for branched-chain amino acids
GKPIPPIE_00732 1.7e-111 endA F DNA RNA non-specific endonuclease
GKPIPPIE_00733 1.6e-74 XK27_02070 S Nitroreductase family
GKPIPPIE_00734 3.8e-191 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
GKPIPPIE_00735 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
GKPIPPIE_00736 5.2e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
GKPIPPIE_00737 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GKPIPPIE_00738 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
GKPIPPIE_00739 5.1e-77 azlC E branched-chain amino acid
GKPIPPIE_00740 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
GKPIPPIE_00741 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
GKPIPPIE_00742 2.1e-55 jag S R3H domain protein
GKPIPPIE_00743 8.8e-127 sip L Belongs to the 'phage' integrase family
GKPIPPIE_00744 4.6e-12 K Cro/C1-type HTH DNA-binding domain
GKPIPPIE_00746 1.5e-38 K COG3617 Prophage antirepressor
GKPIPPIE_00753 2.1e-16
GKPIPPIE_00754 6.7e-46 L DNA replication protein
GKPIPPIE_00755 4.3e-75 S DNA primase
GKPIPPIE_00757 5.7e-13
GKPIPPIE_00758 9.1e-54 K Transcriptional regulator C-terminal region
GKPIPPIE_00759 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
GKPIPPIE_00760 8.4e-284 pepO 3.4.24.71 O Peptidase family M13
GKPIPPIE_00761 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
GKPIPPIE_00762 2.1e-07 S SdpI/YhfL protein family
GKPIPPIE_00763 3e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GKPIPPIE_00764 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
GKPIPPIE_00765 1.3e-40 wecD K Acetyltransferase GNAT Family
GKPIPPIE_00767 1.7e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
GKPIPPIE_00768 2e-251 XK27_06780 V ABC transporter permease
GKPIPPIE_00769 1e-93 XK27_06785 V ABC transporter, ATP-binding protein
GKPIPPIE_00770 6e-11 tetR K transcriptional regulator
GKPIPPIE_00771 3.6e-19
GKPIPPIE_00773 1.3e-71 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKPIPPIE_00774 5.3e-121 ytbE S reductase
GKPIPPIE_00775 4.2e-43 ytcD K HxlR-like helix-turn-helix
GKPIPPIE_00776 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
GKPIPPIE_00777 2e-67 ybbL S ABC transporter
GKPIPPIE_00778 1.4e-162 oxlT P Major Facilitator Superfamily
GKPIPPIE_00779 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKPIPPIE_00780 4.1e-47 S Short repeat of unknown function (DUF308)
GKPIPPIE_00781 1.4e-30 tetR K Transcriptional regulator C-terminal region
GKPIPPIE_00782 1.2e-150 yfeX P Peroxidase
GKPIPPIE_00783 2.5e-16 S Protein of unknown function (DUF3021)
GKPIPPIE_00784 4.5e-39 K LytTr DNA-binding domain
GKPIPPIE_00785 1.4e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
GKPIPPIE_00786 2.1e-207 mmuP E amino acid
GKPIPPIE_00787 9.2e-16 psiE S Phosphate-starvation-inducible E
GKPIPPIE_00788 2.8e-155 oppF P Belongs to the ABC transporter superfamily
GKPIPPIE_00789 1.3e-180 oppD P Belongs to the ABC transporter superfamily
GKPIPPIE_00790 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKPIPPIE_00791 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKPIPPIE_00792 3.6e-203 oppA E ABC transporter, substratebinding protein
GKPIPPIE_00793 3.5e-218 yifK E Amino acid permease
GKPIPPIE_00794 2.4e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKPIPPIE_00795 9.7e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
GKPIPPIE_00796 5e-66 pgm3 G phosphoglycerate mutase family
GKPIPPIE_00797 1.7e-252 ctpA 3.6.3.54 P P-type ATPase
GKPIPPIE_00798 2.5e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GKPIPPIE_00799 9.8e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GKPIPPIE_00800 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GKPIPPIE_00801 7.3e-136 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GKPIPPIE_00802 8.2e-113 lacI3 K helix_turn _helix lactose operon repressor
GKPIPPIE_00803 5.5e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
GKPIPPIE_00804 2e-39 2.7.1.191 G PTS system fructose IIA component
GKPIPPIE_00805 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
GKPIPPIE_00806 2e-86 G PTS system sorbose-specific iic component
GKPIPPIE_00807 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
GKPIPPIE_00808 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GKPIPPIE_00809 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GKPIPPIE_00810 2.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
GKPIPPIE_00811 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
GKPIPPIE_00812 6.2e-30 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
GKPIPPIE_00813 2.1e-24 3.1.3.48 K Transcriptional regulator
GKPIPPIE_00814 4.9e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GKPIPPIE_00815 2.1e-90 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
GKPIPPIE_00817 2.1e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
GKPIPPIE_00818 1.3e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GKPIPPIE_00819 1.6e-81 S Belongs to the UPF0246 family
GKPIPPIE_00820 1.5e-10 S CAAX protease self-immunity
GKPIPPIE_00821 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
GKPIPPIE_00822 1.9e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKPIPPIE_00824 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKPIPPIE_00825 1.8e-64 C FMN binding
GKPIPPIE_00826 4.7e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GKPIPPIE_00827 7.8e-55 rplI J Binds to the 23S rRNA
GKPIPPIE_00828 5.7e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GKPIPPIE_00835 5.1e-08
GKPIPPIE_00844 5.3e-30 yqkB S Belongs to the HesB IscA family
GKPIPPIE_00845 1.1e-64 yxkH G Polysaccharide deacetylase
GKPIPPIE_00846 8.1e-08
GKPIPPIE_00847 1.7e-53 K LysR substrate binding domain
GKPIPPIE_00848 9e-123 MA20_14895 S Conserved hypothetical protein 698
GKPIPPIE_00849 1.3e-200 nupG F Nucleoside
GKPIPPIE_00850 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKPIPPIE_00851 2.4e-48 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKPIPPIE_00852 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GKPIPPIE_00853 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKPIPPIE_00854 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKPIPPIE_00855 9e-20 yaaA S S4 domain protein YaaA
GKPIPPIE_00856 4.2e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKPIPPIE_00857 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKPIPPIE_00858 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKPIPPIE_00859 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
GKPIPPIE_00860 4.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKPIPPIE_00861 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKPIPPIE_00862 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
GKPIPPIE_00863 9.5e-117 S Glycosyl transferase family 2
GKPIPPIE_00864 7.4e-64 D peptidase
GKPIPPIE_00865 0.0 asnB 6.3.5.4 E Asparagine synthase
GKPIPPIE_00866 3.3e-61 yiiE S Protein of unknown function (DUF1211)
GKPIPPIE_00867 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKPIPPIE_00868 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_00869 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_00870 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GKPIPPIE_00871 4.7e-17 yneR
GKPIPPIE_00872 4.3e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKPIPPIE_00873 1.9e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
GKPIPPIE_00874 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GKPIPPIE_00875 2.2e-152 mdtG EGP Major facilitator Superfamily
GKPIPPIE_00876 1.7e-14 yobS K transcriptional regulator
GKPIPPIE_00877 3.7e-109 glcU U sugar transport
GKPIPPIE_00878 2.6e-170 yjjP S Putative threonine/serine exporter
GKPIPPIE_00879 1.8e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
GKPIPPIE_00880 2.4e-95 yicL EG EamA-like transporter family
GKPIPPIE_00881 4.6e-223 pepF E Oligopeptidase F
GKPIPPIE_00882 1.3e-109 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GKPIPPIE_00883 2.9e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GKPIPPIE_00884 1.5e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
GKPIPPIE_00885 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GKPIPPIE_00886 2.8e-24 relB L RelB antitoxin
GKPIPPIE_00887 1.5e-31 S Bacterial toxin of type II toxin-antitoxin system, YafQ
GKPIPPIE_00888 7.5e-173 S Putative peptidoglycan binding domain
GKPIPPIE_00889 7.1e-32 K Transcriptional regulator, MarR family
GKPIPPIE_00890 9e-216 XK27_09600 V ABC transporter, ATP-binding protein
GKPIPPIE_00891 6.4e-241 V ABC transporter transmembrane region
GKPIPPIE_00892 7.2e-107 yxeH S hydrolase
GKPIPPIE_00893 1.3e-112 K response regulator
GKPIPPIE_00894 1.5e-272 vicK 2.7.13.3 T Histidine kinase
GKPIPPIE_00895 6.7e-102 yycH S YycH protein
GKPIPPIE_00896 5.6e-80 yycI S YycH protein
GKPIPPIE_00897 7.4e-15 yyaQ S YjbR
GKPIPPIE_00898 3.7e-116 vicX 3.1.26.11 S domain protein
GKPIPPIE_00899 3.7e-145 htrA 3.4.21.107 O serine protease
GKPIPPIE_00900 4e-73 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKPIPPIE_00901 5.6e-54 1.6.5.2 GM NAD(P)H-binding
GKPIPPIE_00902 4.3e-25 K MarR family transcriptional regulator
GKPIPPIE_00903 7.8e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
GKPIPPIE_00904 2.1e-48 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GKPIPPIE_00905 1.6e-207 G glycerol-3-phosphate transporter
GKPIPPIE_00906 2.5e-137 S interspecies interaction between organisms
GKPIPPIE_00909 3.9e-10 3.1.3.48 D FIVAR domain
GKPIPPIE_00911 4.8e-10 cpsJ M Glycosyltransferase group 2 family protein
GKPIPPIE_00912 8.7e-37 arbx M family 8
GKPIPPIE_00914 2.2e-150 mepA V MATE efflux family protein
GKPIPPIE_00915 4.7e-149 lsa S ABC transporter
GKPIPPIE_00916 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKPIPPIE_00917 1e-109 puuD S peptidase C26
GKPIPPIE_00918 1.1e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GKPIPPIE_00919 1.1e-25
GKPIPPIE_00920 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
GKPIPPIE_00921 2.9e-60 uspA T Universal stress protein family
GKPIPPIE_00923 4.7e-210 glnP P ABC transporter
GKPIPPIE_00924 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GKPIPPIE_00925 3.9e-147 scrR K helix_turn _helix lactose operon repressor
GKPIPPIE_00926 3.1e-217 scrB 3.2.1.26 GH32 G invertase
GKPIPPIE_00927 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
GKPIPPIE_00928 9.1e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GKPIPPIE_00929 1.2e-114 ntpJ P Potassium uptake protein
GKPIPPIE_00930 2.8e-58 ktrA P TrkA-N domain
GKPIPPIE_00931 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GKPIPPIE_00932 2e-37 M Glycosyltransferase group 2 family protein
GKPIPPIE_00933 1.9e-19
GKPIPPIE_00934 4e-94 S Predicted membrane protein (DUF2207)
GKPIPPIE_00935 7.9e-54 bioY S BioY family
GKPIPPIE_00936 5.4e-182 lmrB EGP Major facilitator Superfamily
GKPIPPIE_00937 6.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GKPIPPIE_00938 7.6e-74 glcR K DeoR C terminal sensor domain
GKPIPPIE_00939 5.9e-61 yceE S haloacid dehalogenase-like hydrolase
GKPIPPIE_00940 4.3e-41 S CAAX protease self-immunity
GKPIPPIE_00941 5.3e-34 S Domain of unknown function (DUF4811)
GKPIPPIE_00942 2.1e-197 lmrB EGP Major facilitator Superfamily
GKPIPPIE_00943 4.2e-32 merR K MerR HTH family regulatory protein
GKPIPPIE_00944 6.7e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKPIPPIE_00945 9.1e-71 S Protein of unknown function (DUF554)
GKPIPPIE_00946 1.8e-120 G Bacterial extracellular solute-binding protein
GKPIPPIE_00947 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
GKPIPPIE_00948 3.9e-99 baeS T Histidine kinase
GKPIPPIE_00949 7e-80 rbsB G sugar-binding domain protein
GKPIPPIE_00950 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GKPIPPIE_00951 4.9e-116 manY G PTS system sorbose-specific iic component
GKPIPPIE_00952 2.1e-147 manN G system, mannose fructose sorbose family IID component
GKPIPPIE_00953 3.2e-52 manO S Domain of unknown function (DUF956)
GKPIPPIE_00954 2.1e-70 mltD CBM50 M NlpC P60 family protein
GKPIPPIE_00955 8.1e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKPIPPIE_00956 4.2e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKPIPPIE_00957 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
GKPIPPIE_00958 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GKPIPPIE_00959 8.1e-38 K transcriptional regulator PadR family
GKPIPPIE_00960 2.5e-19 XK27_06920 S Protein of unknown function (DUF1700)
GKPIPPIE_00961 4.1e-16 S Putative adhesin
GKPIPPIE_00962 2.2e-16 pspC KT PspC domain
GKPIPPIE_00964 3e-13 S Enterocin A Immunity
GKPIPPIE_00965 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKPIPPIE_00966 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
GKPIPPIE_00967 1.6e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GKPIPPIE_00968 2.4e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKPIPPIE_00969 1.5e-120 potB P ABC transporter permease
GKPIPPIE_00970 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
GKPIPPIE_00971 1.7e-159 potD P ABC transporter
GKPIPPIE_00972 1e-131 ABC-SBP S ABC transporter
GKPIPPIE_00973 1.3e-112 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GKPIPPIE_00974 2.7e-108 XK27_08845 S ABC transporter, ATP-binding protein
GKPIPPIE_00975 9.7e-67 M ErfK YbiS YcfS YnhG
GKPIPPIE_00976 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKPIPPIE_00977 3.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKPIPPIE_00978 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKPIPPIE_00979 1.2e-102 pgm3 G phosphoglycerate mutase
GKPIPPIE_00980 2.1e-56 S CAAX protease self-immunity
GKPIPPIE_00981 4.8e-47 C Flavodoxin
GKPIPPIE_00982 6.9e-58 yphH S Cupin domain
GKPIPPIE_00983 2.3e-45 yphJ 4.1.1.44 S decarboxylase
GKPIPPIE_00984 2.3e-143 E methionine synthase, vitamin-B12 independent
GKPIPPIE_00985 6.7e-108 metQ1 P Belongs to the nlpA lipoprotein family
GKPIPPIE_00986 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKPIPPIE_00987 6.7e-69 metI P ABC transporter permease
GKPIPPIE_00988 1.3e-133 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GKPIPPIE_00989 2.3e-84 drgA C nitroreductase
GKPIPPIE_00990 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
GKPIPPIE_00991 2.5e-105 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GKPIPPIE_00992 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GKPIPPIE_00993 6.9e-263 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
GKPIPPIE_00995 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKPIPPIE_00996 2.4e-31 metI U ABC transporter permease
GKPIPPIE_00997 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
GKPIPPIE_00998 8.2e-54 S Protein of unknown function (DUF4256)
GKPIPPIE_01000 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
GKPIPPIE_01001 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GKPIPPIE_01002 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GKPIPPIE_01003 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKPIPPIE_01004 4e-230 lpdA 1.8.1.4 C Dehydrogenase
GKPIPPIE_01005 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
GKPIPPIE_01006 7.1e-56 S Protein of unknown function (DUF975)
GKPIPPIE_01007 1.3e-77 E GDSL-like Lipase/Acylhydrolase family
GKPIPPIE_01008 1.8e-38
GKPIPPIE_01009 4.1e-27 gcvR T Belongs to the UPF0237 family
GKPIPPIE_01010 1.6e-220 XK27_08635 S UPF0210 protein
GKPIPPIE_01011 2.2e-86 fruR K DeoR C terminal sensor domain
GKPIPPIE_01012 2e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKPIPPIE_01013 3.3e-283 fruA 2.7.1.202 GT Phosphotransferase System
GKPIPPIE_01014 1.6e-49 cps3F
GKPIPPIE_01015 2.7e-83 S Membrane
GKPIPPIE_01016 1.8e-254 E Amino acid permease
GKPIPPIE_01017 8.5e-225 cadA P P-type ATPase
GKPIPPIE_01018 6.4e-114 degV S EDD domain protein, DegV family
GKPIPPIE_01019 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GKPIPPIE_01020 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
GKPIPPIE_01021 3.6e-26 ydiI Q Thioesterase superfamily
GKPIPPIE_01022 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKPIPPIE_01023 4.3e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GKPIPPIE_01024 4.7e-81 S L,D-transpeptidase catalytic domain
GKPIPPIE_01025 1.5e-165 EGP Major facilitator Superfamily
GKPIPPIE_01026 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
GKPIPPIE_01027 1.7e-225 pipD E Dipeptidase
GKPIPPIE_01028 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GKPIPPIE_01029 2.6e-32 ywjH S Protein of unknown function (DUF1634)
GKPIPPIE_01030 2.2e-119 yxaA S membrane transporter protein
GKPIPPIE_01031 7.6e-83 lysR5 K LysR substrate binding domain
GKPIPPIE_01032 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
GKPIPPIE_01033 2.7e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKPIPPIE_01034 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GKPIPPIE_01035 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
GKPIPPIE_01036 5.5e-243 lysP E amino acid
GKPIPPIE_01037 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKPIPPIE_01049 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GKPIPPIE_01050 5.5e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKPIPPIE_01051 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GKPIPPIE_01052 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GKPIPPIE_01053 5.6e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKPIPPIE_01055 1.6e-55 ctsR K Belongs to the CtsR family
GKPIPPIE_01056 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKPIPPIE_01057 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKPIPPIE_01058 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKPIPPIE_01059 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
GKPIPPIE_01060 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKPIPPIE_01061 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKPIPPIE_01062 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKPIPPIE_01063 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GKPIPPIE_01064 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
GKPIPPIE_01065 2.5e-113 K response regulator
GKPIPPIE_01066 2.2e-141 hpk31 2.7.13.3 T Histidine kinase
GKPIPPIE_01067 2e-91 lacX 5.1.3.3 G Aldose 1-epimerase
GKPIPPIE_01068 1e-146 G Transporter, major facilitator family protein
GKPIPPIE_01069 5.3e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKPIPPIE_01070 5.6e-246 yhcA V ABC transporter, ATP-binding protein
GKPIPPIE_01071 5.8e-35 K Bacterial regulatory proteins, tetR family
GKPIPPIE_01072 3.9e-219 lmrA V ABC transporter, ATP-binding protein
GKPIPPIE_01073 7.4e-253 yfiC V ABC transporter
GKPIPPIE_01075 3.2e-45 yjcF K protein acetylation
GKPIPPIE_01076 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
GKPIPPIE_01077 1.1e-71 lemA S LemA family
GKPIPPIE_01078 1.3e-114 htpX O Belongs to the peptidase M48B family
GKPIPPIE_01080 1.8e-272 helD 3.6.4.12 L DNA helicase
GKPIPPIE_01081 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKPIPPIE_01082 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GKPIPPIE_01083 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GKPIPPIE_01084 1.4e-82 ybhF_2 V abc transporter atp-binding protein
GKPIPPIE_01085 1.7e-66 ybhR V ABC transporter
GKPIPPIE_01086 3.3e-26 ybhR V ABC transporter
GKPIPPIE_01087 2.3e-31 K Transcriptional regulator
GKPIPPIE_01088 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
GKPIPPIE_01089 3.3e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GKPIPPIE_01090 7.3e-127
GKPIPPIE_01091 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKPIPPIE_01092 2.7e-103 tatD L hydrolase, TatD family
GKPIPPIE_01093 4.5e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKPIPPIE_01094 1.9e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKPIPPIE_01095 1.2e-22 veg S Biofilm formation stimulator VEG
GKPIPPIE_01096 4.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
GKPIPPIE_01097 1.5e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
GKPIPPIE_01098 6.6e-46 argR K Regulates arginine biosynthesis genes
GKPIPPIE_01099 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKPIPPIE_01100 1.3e-155 amtB P ammonium transporter
GKPIPPIE_01102 3.5e-91 sip L Belongs to the 'phage' integrase family
GKPIPPIE_01103 3.6e-99 V Abi-like protein
GKPIPPIE_01105 1.1e-09
GKPIPPIE_01108 2.8e-10
GKPIPPIE_01110 1.2e-49 polC 2.7.7.7 L DNA polymerase III
GKPIPPIE_01111 7.4e-10
GKPIPPIE_01112 6.1e-17 E IrrE N-terminal-like domain
GKPIPPIE_01113 1e-26 K Helix-turn-helix XRE-family like proteins
GKPIPPIE_01114 2e-07
GKPIPPIE_01115 1.6e-49 S DNA binding
GKPIPPIE_01121 1.4e-53 S Putative HNHc nuclease
GKPIPPIE_01122 9.5e-29 S Phage replisome organizer, N-terminal domain protein
GKPIPPIE_01125 1.6e-25
GKPIPPIE_01142 1.3e-33 arpU S Phage transcriptional regulator, ArpU family
GKPIPPIE_01144 3.6e-29 S Predicted membrane protein (DUF2335)
GKPIPPIE_01147 1.9e-84 L HNH nucleases
GKPIPPIE_01148 4.3e-83 L Phage terminase, small subunit
GKPIPPIE_01149 0.0 S Phage Terminase
GKPIPPIE_01151 1.3e-194 S Phage portal protein
GKPIPPIE_01152 6.5e-112 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
GKPIPPIE_01153 2.2e-197 S Phage capsid family
GKPIPPIE_01154 8.2e-22 S Phage gp6-like head-tail connector protein
GKPIPPIE_01155 4.5e-53 S Phage head-tail joining protein
GKPIPPIE_01156 7.1e-52 S Bacteriophage HK97-gp10, putative tail-component
GKPIPPIE_01157 3e-55 S Protein of unknown function (DUF806)
GKPIPPIE_01158 5.1e-77 S Phage tail tube protein
GKPIPPIE_01159 7.5e-17 S Phage tail assembly chaperone proteins, TAC
GKPIPPIE_01161 2.6e-276 M Phage tail tape measure protein TP901
GKPIPPIE_01162 1e-76 S Phage tail protein
GKPIPPIE_01163 5e-121 rny D peptidase
GKPIPPIE_01165 3.4e-72 S Domain of unknown function (DUF2479)
GKPIPPIE_01171 3e-128 M Glycosyl hydrolases family 25
GKPIPPIE_01172 1.7e-201 argH 4.3.2.1 E argininosuccinate lyase
GKPIPPIE_01173 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKPIPPIE_01174 4e-151 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GKPIPPIE_01175 1.5e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKPIPPIE_01176 1.8e-102 pfoS S Phosphotransferase system, EIIC
GKPIPPIE_01177 1.9e-88 2.4.1.9 GH68 M MucBP domain
GKPIPPIE_01178 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_01179 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_01180 1.4e-290 ybiT S ABC transporter, ATP-binding protein
GKPIPPIE_01181 3.3e-77 2.4.2.3 F Phosphorylase superfamily
GKPIPPIE_01182 1.7e-24
GKPIPPIE_01183 1.2e-112 dkg S reductase
GKPIPPIE_01185 4.3e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKPIPPIE_01186 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKPIPPIE_01187 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKPIPPIE_01188 1.9e-47 EGP Transmembrane secretion effector
GKPIPPIE_01189 5.2e-137 purR 2.4.2.7 F pur operon repressor
GKPIPPIE_01190 6.1e-18 S YCII-related domain
GKPIPPIE_01191 2.1e-70 ywrO S Flavodoxin-like fold
GKPIPPIE_01192 3.9e-53 adhR K helix_turn_helix, mercury resistance
GKPIPPIE_01193 1.3e-183 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKPIPPIE_01194 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_01195 5.1e-90 L PFAM Integrase catalytic region
GKPIPPIE_01196 6.2e-36 ytkL S Belongs to the UPF0173 family
GKPIPPIE_01197 1.7e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKPIPPIE_01198 6.9e-121 S overlaps another CDS with the same product name
GKPIPPIE_01199 1.7e-86 S overlaps another CDS with the same product name
GKPIPPIE_01201 2.5e-55 spoVK O ATPase family associated with various cellular activities (AAA)
GKPIPPIE_01202 5.5e-08
GKPIPPIE_01204 1.6e-38 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
GKPIPPIE_01206 1e-71
GKPIPPIE_01207 2.8e-22
GKPIPPIE_01208 1e-104 ydcZ S Putative inner membrane exporter, YdcZ
GKPIPPIE_01209 6.3e-66 S hydrolase
GKPIPPIE_01211 8.6e-206 ywfO S HD domain protein
GKPIPPIE_01212 2.2e-85 yfeJ 6.3.5.2 F glutamine amidotransferase
GKPIPPIE_01213 1.8e-32 ywiB S Domain of unknown function (DUF1934)
GKPIPPIE_01214 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKPIPPIE_01215 2.5e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKPIPPIE_01217 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKPIPPIE_01218 5.9e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GKPIPPIE_01219 3.6e-41 rpmE2 J Ribosomal protein L31
GKPIPPIE_01220 1.1e-60
GKPIPPIE_01221 1.3e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
GKPIPPIE_01223 8e-79 S Cell surface protein
GKPIPPIE_01225 6e-180 pbuG S permease
GKPIPPIE_01226 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
GKPIPPIE_01227 6.3e-180 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKPIPPIE_01228 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKPIPPIE_01229 2.1e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKPIPPIE_01230 6.3e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKPIPPIE_01231 5.4e-13
GKPIPPIE_01232 7.6e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
GKPIPPIE_01233 7.4e-91 yunF F Protein of unknown function DUF72
GKPIPPIE_01234 1.1e-155 nrnB S DHHA1 domain
GKPIPPIE_01235 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKPIPPIE_01236 2.9e-59
GKPIPPIE_01237 5.6e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
GKPIPPIE_01238 7.1e-13 S Cytochrome B5
GKPIPPIE_01239 1.1e-19 sigH K DNA-templated transcription, initiation
GKPIPPIE_01240 5e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
GKPIPPIE_01241 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKPIPPIE_01242 2.6e-97 ygaC J Belongs to the UPF0374 family
GKPIPPIE_01243 3.4e-91 yueF S AI-2E family transporter
GKPIPPIE_01244 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GKPIPPIE_01245 6.7e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GKPIPPIE_01246 1.2e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKPIPPIE_01247 6.3e-36
GKPIPPIE_01248 0.0 lacL 3.2.1.23 G -beta-galactosidase
GKPIPPIE_01249 8.9e-289 lacS G Transporter
GKPIPPIE_01250 5.9e-111 galR K Transcriptional regulator
GKPIPPIE_01251 5.3e-180 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKPIPPIE_01252 3.9e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GKPIPPIE_01253 1.3e-199 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GKPIPPIE_01254 2.3e-309 rafA 3.2.1.22 G alpha-galactosidase
GKPIPPIE_01255 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GKPIPPIE_01256 7.3e-22 XK27_09445 S Domain of unknown function (DUF1827)
GKPIPPIE_01257 0.0 clpE O Belongs to the ClpA ClpB family
GKPIPPIE_01258 1.5e-15
GKPIPPIE_01259 9.7e-37 ptsH G phosphocarrier protein HPR
GKPIPPIE_01260 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKPIPPIE_01261 1.5e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GKPIPPIE_01262 1.7e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
GKPIPPIE_01263 5.1e-126 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKPIPPIE_01264 1.5e-25 ykuJ S Protein of unknown function (DUF1797)
GKPIPPIE_01265 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKPIPPIE_01274 5.1e-08
GKPIPPIE_01280 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
GKPIPPIE_01281 7.1e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKPIPPIE_01282 5.5e-68 coiA 3.6.4.12 S Competence protein
GKPIPPIE_01283 9.6e-232 pepF E oligoendopeptidase F
GKPIPPIE_01284 1.3e-41 yjbH Q Thioredoxin
GKPIPPIE_01285 4.1e-97 pstS P Phosphate
GKPIPPIE_01286 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
GKPIPPIE_01287 5.1e-122 pstA P Phosphate transport system permease protein PstA
GKPIPPIE_01288 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKPIPPIE_01289 3e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKPIPPIE_01290 2.7e-56 P Plays a role in the regulation of phosphate uptake
GKPIPPIE_01291 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GKPIPPIE_01292 1.1e-79 S VIT family
GKPIPPIE_01293 9.4e-84 S membrane
GKPIPPIE_01294 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
GKPIPPIE_01295 5.2e-65 hly S protein, hemolysin III
GKPIPPIE_01296 2.7e-34 K helix_turn_helix, Arsenical Resistance Operon Repressor
GKPIPPIE_01297 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKPIPPIE_01300 3e-14
GKPIPPIE_01301 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GKPIPPIE_01302 1.3e-158 ccpA K catabolite control protein A
GKPIPPIE_01303 3.7e-42 S VanZ like family
GKPIPPIE_01304 1.5e-119 yebC K Transcriptional regulatory protein
GKPIPPIE_01305 4.6e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKPIPPIE_01306 8.1e-121 comGA NU Type II IV secretion system protein
GKPIPPIE_01307 5.7e-98 comGB NU type II secretion system
GKPIPPIE_01308 1.2e-27 comGC U competence protein ComGC
GKPIPPIE_01309 1.5e-13
GKPIPPIE_01311 5.5e-11 S Putative Competence protein ComGF
GKPIPPIE_01313 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
GKPIPPIE_01314 1.6e-183 cycA E Amino acid permease
GKPIPPIE_01315 3e-57 S Calcineurin-like phosphoesterase
GKPIPPIE_01316 1.9e-53 yutD S Protein of unknown function (DUF1027)
GKPIPPIE_01317 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKPIPPIE_01318 7.8e-32 S Protein of unknown function (DUF1461)
GKPIPPIE_01319 5.1e-92 dedA S SNARE associated Golgi protein
GKPIPPIE_01320 9.4e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GKPIPPIE_01321 8.8e-50 yugI 5.3.1.9 J general stress protein
GKPIPPIE_01331 2.1e-07
GKPIPPIE_01341 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKPIPPIE_01342 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GKPIPPIE_01343 2.4e-192 cycA E Amino acid permease
GKPIPPIE_01344 6.4e-187 ytgP S Polysaccharide biosynthesis protein
GKPIPPIE_01345 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GKPIPPIE_01346 2.7e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKPIPPIE_01347 3.3e-192 pepV 3.5.1.18 E dipeptidase PepV
GKPIPPIE_01349 3e-36
GKPIPPIE_01350 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKPIPPIE_01351 4.2e-61 marR K Transcriptional regulator, MarR family
GKPIPPIE_01352 1.9e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKPIPPIE_01353 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKPIPPIE_01354 8.6e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GKPIPPIE_01355 1.1e-98 IQ reductase
GKPIPPIE_01356 4.8e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKPIPPIE_01357 1.3e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKPIPPIE_01358 3e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKPIPPIE_01359 5.5e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GKPIPPIE_01360 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKPIPPIE_01361 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GKPIPPIE_01362 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GKPIPPIE_01363 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKPIPPIE_01364 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
GKPIPPIE_01365 5.5e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKPIPPIE_01366 5.7e-119 gla U Major intrinsic protein
GKPIPPIE_01367 5.8e-45 ykuL S CBS domain
GKPIPPIE_01368 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKPIPPIE_01369 5.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKPIPPIE_01370 1.5e-86 ykuT M mechanosensitive ion channel
GKPIPPIE_01372 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GKPIPPIE_01373 2e-21 yheA S Belongs to the UPF0342 family
GKPIPPIE_01374 8.6e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
GKPIPPIE_01375 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKPIPPIE_01377 7e-53 hit FG histidine triad
GKPIPPIE_01378 9.8e-95 ecsA V ABC transporter, ATP-binding protein
GKPIPPIE_01379 8.4e-72 ecsB U ABC transporter
GKPIPPIE_01380 9.1e-99 ytmP 2.7.1.89 M Choline/ethanolamine kinase
GKPIPPIE_01381 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKPIPPIE_01382 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GKPIPPIE_01383 1.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKPIPPIE_01384 4.4e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
GKPIPPIE_01385 1.3e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GKPIPPIE_01386 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
GKPIPPIE_01387 1.9e-68 ybhL S Belongs to the BI1 family
GKPIPPIE_01388 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKPIPPIE_01389 1.2e-106 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKPIPPIE_01390 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKPIPPIE_01391 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKPIPPIE_01392 3.6e-79 dnaB L replication initiation and membrane attachment
GKPIPPIE_01393 3.3e-108 dnaI L Primosomal protein DnaI
GKPIPPIE_01394 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKPIPPIE_01395 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKPIPPIE_01396 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GKPIPPIE_01397 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKPIPPIE_01398 1.6e-70 yqeG S HAD phosphatase, family IIIA
GKPIPPIE_01399 3.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
GKPIPPIE_01400 6e-30 yhbY J RNA-binding protein
GKPIPPIE_01401 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKPIPPIE_01402 1.5e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GKPIPPIE_01403 1.1e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKPIPPIE_01404 5.5e-82 H Nodulation protein S (NodS)
GKPIPPIE_01405 1.1e-121 ylbM S Belongs to the UPF0348 family
GKPIPPIE_01406 1.9e-55 yceD S Uncharacterized ACR, COG1399
GKPIPPIE_01407 1.6e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GKPIPPIE_01408 1.2e-88 plsC 2.3.1.51 I Acyltransferase
GKPIPPIE_01409 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
GKPIPPIE_01410 1.5e-27 yazA L GIY-YIG catalytic domain protein
GKPIPPIE_01411 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
GKPIPPIE_01412 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKPIPPIE_01413 6.9e-37
GKPIPPIE_01414 3e-73 L PFAM transposase IS200-family protein
GKPIPPIE_01415 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GKPIPPIE_01416 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKPIPPIE_01417 2.9e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKPIPPIE_01418 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKPIPPIE_01419 3e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKPIPPIE_01421 3.1e-111 K response regulator
GKPIPPIE_01422 1.3e-167 arlS 2.7.13.3 T Histidine kinase
GKPIPPIE_01423 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKPIPPIE_01424 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GKPIPPIE_01425 1.8e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GKPIPPIE_01426 7.3e-105
GKPIPPIE_01427 7.2e-117
GKPIPPIE_01428 7.1e-40 dut S dUTPase
GKPIPPIE_01429 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKPIPPIE_01430 3.7e-46 yqhY S Asp23 family, cell envelope-related function
GKPIPPIE_01431 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKPIPPIE_01432 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKPIPPIE_01433 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKPIPPIE_01434 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKPIPPIE_01435 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GKPIPPIE_01436 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GKPIPPIE_01437 6.6e-49 argR K Regulates arginine biosynthesis genes
GKPIPPIE_01438 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
GKPIPPIE_01439 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKPIPPIE_01440 2.2e-30 ynzC S UPF0291 protein
GKPIPPIE_01441 5.9e-27 yneF S UPF0154 protein
GKPIPPIE_01442 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
GKPIPPIE_01443 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
GKPIPPIE_01444 1.2e-74 yciQ P membrane protein (DUF2207)
GKPIPPIE_01445 3e-19 D nuclear chromosome segregation
GKPIPPIE_01446 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GKPIPPIE_01447 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKPIPPIE_01448 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
GKPIPPIE_01449 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
GKPIPPIE_01450 4.7e-158 glk 2.7.1.2 G Glucokinase
GKPIPPIE_01451 2.7e-46 yqhL P Rhodanese-like protein
GKPIPPIE_01452 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
GKPIPPIE_01453 2.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKPIPPIE_01454 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
GKPIPPIE_01455 1.3e-45 glnR K Transcriptional regulator
GKPIPPIE_01456 7.6e-247 glnA 6.3.1.2 E glutamine synthetase
GKPIPPIE_01458 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKPIPPIE_01459 2.7e-48 S Domain of unknown function (DUF956)
GKPIPPIE_01460 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GKPIPPIE_01461 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKPIPPIE_01462 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKPIPPIE_01463 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
GKPIPPIE_01464 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GKPIPPIE_01465 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKPIPPIE_01466 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKPIPPIE_01467 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
GKPIPPIE_01468 1.1e-169 nusA K Participates in both transcription termination and antitermination
GKPIPPIE_01469 1.4e-39 ylxR K Protein of unknown function (DUF448)
GKPIPPIE_01470 6.8e-26 ylxQ J ribosomal protein
GKPIPPIE_01471 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKPIPPIE_01472 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKPIPPIE_01473 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKPIPPIE_01474 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GKPIPPIE_01475 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKPIPPIE_01476 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKPIPPIE_01477 1.5e-274 dnaK O Heat shock 70 kDa protein
GKPIPPIE_01478 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKPIPPIE_01479 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKPIPPIE_01481 9.2e-206 glnP P ABC transporter
GKPIPPIE_01482 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GKPIPPIE_01483 1.5e-31
GKPIPPIE_01484 2e-111 ampC V Beta-lactamase
GKPIPPIE_01485 3.5e-110 cobQ S glutamine amidotransferase
GKPIPPIE_01486 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
GKPIPPIE_01487 6.8e-86 tdk 2.7.1.21 F thymidine kinase
GKPIPPIE_01488 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKPIPPIE_01489 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKPIPPIE_01490 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKPIPPIE_01491 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKPIPPIE_01492 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
GKPIPPIE_01493 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKPIPPIE_01494 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKPIPPIE_01495 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKPIPPIE_01496 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKPIPPIE_01497 1.7e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKPIPPIE_01498 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKPIPPIE_01499 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GKPIPPIE_01500 4.1e-15 ywzB S Protein of unknown function (DUF1146)
GKPIPPIE_01501 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKPIPPIE_01502 3.4e-167 mbl D Cell shape determining protein MreB Mrl
GKPIPPIE_01503 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GKPIPPIE_01504 1.3e-13 S Protein of unknown function (DUF2969)
GKPIPPIE_01505 6.1e-187 rodA D Belongs to the SEDS family
GKPIPPIE_01506 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
GKPIPPIE_01507 4.7e-93 2.7.1.89 M Phosphotransferase enzyme family
GKPIPPIE_01508 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GKPIPPIE_01509 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKPIPPIE_01510 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKPIPPIE_01511 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKPIPPIE_01512 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKPIPPIE_01513 3.4e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKPIPPIE_01514 3.3e-90 stp 3.1.3.16 T phosphatase
GKPIPPIE_01515 3.4e-191 KLT serine threonine protein kinase
GKPIPPIE_01516 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKPIPPIE_01517 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
GKPIPPIE_01518 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GKPIPPIE_01519 4.5e-53 asp S Asp23 family, cell envelope-related function
GKPIPPIE_01520 1.3e-238 yloV S DAK2 domain fusion protein YloV
GKPIPPIE_01521 1.1e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKPIPPIE_01522 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKPIPPIE_01523 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKPIPPIE_01524 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKPIPPIE_01525 1.1e-207 smc D Required for chromosome condensation and partitioning
GKPIPPIE_01526 1.8e-144 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKPIPPIE_01527 2.7e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKPIPPIE_01528 2.5e-203 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKPIPPIE_01529 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GKPIPPIE_01530 1.1e-26 ylqC S Belongs to the UPF0109 family
GKPIPPIE_01531 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKPIPPIE_01532 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GKPIPPIE_01533 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
GKPIPPIE_01534 1.4e-60 yfnA E amino acid
GKPIPPIE_01535 5.2e-125 yfnA E amino acid
GKPIPPIE_01536 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKPIPPIE_01537 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
GKPIPPIE_01538 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKPIPPIE_01539 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKPIPPIE_01540 2.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKPIPPIE_01541 6.1e-19 S Tetratricopeptide repeat
GKPIPPIE_01542 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKPIPPIE_01543 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKPIPPIE_01544 3.9e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKPIPPIE_01545 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKPIPPIE_01546 3.3e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKPIPPIE_01547 2.5e-22 ykzG S Belongs to the UPF0356 family
GKPIPPIE_01548 5.5e-25
GKPIPPIE_01549 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKPIPPIE_01550 4e-31 1.1.1.27 C L-malate dehydrogenase activity
GKPIPPIE_01551 1.7e-23 yktA S Belongs to the UPF0223 family
GKPIPPIE_01552 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GKPIPPIE_01553 0.0 typA T GTP-binding protein TypA
GKPIPPIE_01554 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GKPIPPIE_01555 7e-115 manY G PTS system
GKPIPPIE_01556 3.3e-148 manN G system, mannose fructose sorbose family IID component
GKPIPPIE_01557 3e-101 ftsW D Belongs to the SEDS family
GKPIPPIE_01558 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GKPIPPIE_01559 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GKPIPPIE_01560 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GKPIPPIE_01561 5.3e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKPIPPIE_01562 4.1e-131 ylbL T Belongs to the peptidase S16 family
GKPIPPIE_01563 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GKPIPPIE_01564 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKPIPPIE_01565 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKPIPPIE_01566 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKPIPPIE_01567 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKPIPPIE_01568 6.9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GKPIPPIE_01569 2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKPIPPIE_01570 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GKPIPPIE_01571 7.1e-162 purD 6.3.4.13 F Belongs to the GARS family
GKPIPPIE_01572 1.2e-106 S Acyltransferase family
GKPIPPIE_01573 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKPIPPIE_01574 5e-122 K LysR substrate binding domain
GKPIPPIE_01576 2.2e-20
GKPIPPIE_01577 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GKPIPPIE_01578 7.5e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
GKPIPPIE_01579 4e-50 comEA L Competence protein ComEA
GKPIPPIE_01580 2e-69 comEB 3.5.4.12 F ComE operon protein 2
GKPIPPIE_01581 5.5e-157 comEC S Competence protein ComEC
GKPIPPIE_01582 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
GKPIPPIE_01583 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKPIPPIE_01584 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GKPIPPIE_01585 1.3e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GKPIPPIE_01586 4.7e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GKPIPPIE_01587 3.9e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GKPIPPIE_01588 1.8e-36 ypmB S Protein conserved in bacteria
GKPIPPIE_01589 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GKPIPPIE_01590 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GKPIPPIE_01591 3.2e-15 dnaD L DnaD domain protein
GKPIPPIE_01592 2.1e-24 dnaD L DnaD domain protein
GKPIPPIE_01593 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKPIPPIE_01594 4.9e-77 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKPIPPIE_01595 1.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKPIPPIE_01596 8.6e-94 M transferase activity, transferring glycosyl groups
GKPIPPIE_01597 2.8e-84 M Glycosyltransferase sugar-binding region containing DXD motif
GKPIPPIE_01598 5.8e-100 epsJ1 M Glycosyltransferase like family 2
GKPIPPIE_01601 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKPIPPIE_01602 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GKPIPPIE_01603 1.8e-56 yqeY S YqeY-like protein
GKPIPPIE_01605 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
GKPIPPIE_01606 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKPIPPIE_01607 1.8e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKPIPPIE_01608 3.3e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKPIPPIE_01609 3.2e-275 yfmR S ABC transporter, ATP-binding protein
GKPIPPIE_01610 1.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKPIPPIE_01611 2.3e-26 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKPIPPIE_01612 8.5e-17 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKPIPPIE_01614 3.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
GKPIPPIE_01615 4.4e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GKPIPPIE_01616 3.6e-24 yozE S Belongs to the UPF0346 family
GKPIPPIE_01617 1.2e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKPIPPIE_01618 3.1e-96 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKPIPPIE_01619 6.2e-85 dprA LU DNA protecting protein DprA
GKPIPPIE_01620 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKPIPPIE_01621 3.6e-209 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKPIPPIE_01622 1.1e-203 G PTS system Galactitol-specific IIC component
GKPIPPIE_01623 5.5e-154 M Exporter of polyketide antibiotics
GKPIPPIE_01624 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GKPIPPIE_01625 3.5e-35 S Repeat protein
GKPIPPIE_01626 6.9e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKPIPPIE_01628 1.4e-92 L Belongs to the 'phage' integrase family
GKPIPPIE_01629 1.9e-14 L Belongs to the 'phage' integrase family
GKPIPPIE_01631 1.1e-25 ligA 2.7.7.7, 6.5.1.2 L EXOIII
GKPIPPIE_01632 1.9e-13
GKPIPPIE_01633 3.4e-18 L nuclease
GKPIPPIE_01634 2.1e-27 S Short C-terminal domain
GKPIPPIE_01636 2.9e-35 E Zn peptidase
GKPIPPIE_01637 3.1e-37 K Helix-turn-helix XRE-family like proteins
GKPIPPIE_01638 5.9e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
GKPIPPIE_01642 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKPIPPIE_01643 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GKPIPPIE_01644 9.1e-43 yodB K Transcriptional regulator, HxlR family
GKPIPPIE_01645 1.3e-172 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKPIPPIE_01646 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKPIPPIE_01647 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKPIPPIE_01648 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
GKPIPPIE_01649 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKPIPPIE_01650 1.3e-29 L Helix-turn-helix domain
GKPIPPIE_01651 1.5e-89 L PFAM Integrase catalytic region
GKPIPPIE_01652 3.8e-12
GKPIPPIE_01653 4.3e-143 iunH2 3.2.2.1 F nucleoside hydrolase
GKPIPPIE_01654 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
GKPIPPIE_01655 9.9e-118 prmA J Ribosomal protein L11 methyltransferase
GKPIPPIE_01656 1.8e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKPIPPIE_01657 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKPIPPIE_01658 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKPIPPIE_01659 9.7e-56 3.1.3.18 J HAD-hyrolase-like
GKPIPPIE_01660 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKPIPPIE_01661 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GKPIPPIE_01662 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKPIPPIE_01663 5.9e-204 pyrP F Permease
GKPIPPIE_01664 5.7e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GKPIPPIE_01665 7.7e-192 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GKPIPPIE_01666 3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKPIPPIE_01667 1.4e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKPIPPIE_01668 4.7e-134 K Transcriptional regulator
GKPIPPIE_01669 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
GKPIPPIE_01670 1.9e-114 glcR K DeoR C terminal sensor domain
GKPIPPIE_01671 1.2e-171 patA 2.6.1.1 E Aminotransferase
GKPIPPIE_01672 7.1e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GKPIPPIE_01674 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKPIPPIE_01675 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GKPIPPIE_01676 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
GKPIPPIE_01677 6.6e-23 S Family of unknown function (DUF5322)
GKPIPPIE_01678 5.9e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GKPIPPIE_01679 1.8e-38
GKPIPPIE_01685 7.4e-149 EGP Sugar (and other) transporter
GKPIPPIE_01686 2.7e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
GKPIPPIE_01687 4.3e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKPIPPIE_01688 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GKPIPPIE_01689 3.3e-70 alkD L DNA alkylation repair enzyme
GKPIPPIE_01690 4.9e-136 EG EamA-like transporter family
GKPIPPIE_01691 3.6e-150 S Tetratricopeptide repeat protein
GKPIPPIE_01692 4.1e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
GKPIPPIE_01693 6.6e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKPIPPIE_01694 5.4e-127 corA P CorA-like Mg2+ transporter protein
GKPIPPIE_01695 1.9e-160 nhaC C Na H antiporter NhaC
GKPIPPIE_01696 2.3e-128 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKPIPPIE_01697 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GKPIPPIE_01699 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKPIPPIE_01700 1.7e-159 iscS 2.8.1.7 E Aminotransferase class V
GKPIPPIE_01701 3.7e-41 XK27_04120 S Putative amino acid metabolism
GKPIPPIE_01702 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKPIPPIE_01703 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKPIPPIE_01704 4.3e-15 S Protein of unknown function (DUF2929)
GKPIPPIE_01705 0.0 dnaE 2.7.7.7 L DNA polymerase
GKPIPPIE_01706 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKPIPPIE_01707 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GKPIPPIE_01709 2.2e-39 ypaA S Protein of unknown function (DUF1304)
GKPIPPIE_01710 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKPIPPIE_01711 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKPIPPIE_01712 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKPIPPIE_01713 1.9e-202 FbpA K Fibronectin-binding protein
GKPIPPIE_01714 3.1e-40 K Transcriptional regulator
GKPIPPIE_01715 6.3e-117 degV S EDD domain protein, DegV family
GKPIPPIE_01716 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
GKPIPPIE_01717 9.3e-40 6.3.3.2 S ASCH
GKPIPPIE_01718 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKPIPPIE_01719 3.8e-79 yjjH S Calcineurin-like phosphoesterase
GKPIPPIE_01720 1.8e-95 EG EamA-like transporter family
GKPIPPIE_01721 2.5e-84 natB CP ABC-type Na efflux pump, permease component
GKPIPPIE_01722 2.8e-112 natA S Domain of unknown function (DUF4162)
GKPIPPIE_01723 3.7e-23 K Acetyltransferase (GNAT) domain
GKPIPPIE_01725 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKPIPPIE_01726 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GKPIPPIE_01727 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
GKPIPPIE_01728 1.3e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
GKPIPPIE_01729 4.4e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKPIPPIE_01730 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKPIPPIE_01731 5.3e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
GKPIPPIE_01732 1.2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKPIPPIE_01733 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
GKPIPPIE_01734 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
GKPIPPIE_01735 1.7e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKPIPPIE_01736 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GKPIPPIE_01737 2.3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKPIPPIE_01738 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
GKPIPPIE_01739 2.6e-83 lytH 3.5.1.28 M Ami_3
GKPIPPIE_01740 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GKPIPPIE_01741 7.7e-12 M Lysin motif
GKPIPPIE_01742 2.6e-128 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GKPIPPIE_01743 8.4e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
GKPIPPIE_01744 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
GKPIPPIE_01745 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
GKPIPPIE_01746 8.4e-121 ica2 GT2 M Glycosyl transferase family group 2
GKPIPPIE_01747 1.7e-44
GKPIPPIE_01748 9.5e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKPIPPIE_01750 1.4e-185 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKPIPPIE_01751 2.9e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKPIPPIE_01752 4.3e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GKPIPPIE_01753 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GKPIPPIE_01754 3e-92 S Aldo/keto reductase family
GKPIPPIE_01755 4.2e-37 fldA C Flavodoxin
GKPIPPIE_01756 4e-15 P esterase
GKPIPPIE_01758 2e-80 GM NmrA-like family
GKPIPPIE_01759 1.2e-117 EGP Major Facilitator Superfamily
GKPIPPIE_01760 6.6e-127 akr5f 1.1.1.346 S reductase
GKPIPPIE_01761 1.2e-72 K Transcriptional regulator
GKPIPPIE_01762 1.3e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
GKPIPPIE_01763 8.8e-70 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKPIPPIE_01764 1e-43 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_01765 3.6e-131 L Belongs to the 'phage' integrase family
GKPIPPIE_01766 1.6e-84 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_01768 4.4e-201 hsdM 2.1.1.72 V type I restriction-modification system
GKPIPPIE_01769 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GKPIPPIE_01771 8.7e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
GKPIPPIE_01772 1.7e-55 3.6.1.27 I Acid phosphatase homologues
GKPIPPIE_01773 1.1e-67 maa 2.3.1.79 S Maltose acetyltransferase
GKPIPPIE_01774 8.2e-73 2.3.1.178 M GNAT acetyltransferase
GKPIPPIE_01776 8.3e-13 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GKPIPPIE_01777 1e-45 ade 3.5.4.2 F Adenine deaminase C-terminal domain
GKPIPPIE_01778 1.7e-26 ade 3.5.4.2 F Adenine deaminase C-terminal domain
GKPIPPIE_01779 2.8e-09 ade 3.5.4.2 F Adenine deaminase C-terminal domain
GKPIPPIE_01780 9.8e-41 ypsA S Belongs to the UPF0398 family
GKPIPPIE_01782 2.5e-46 nhaC C Na H antiporter NhaC
GKPIPPIE_01783 2.1e-56 nhaC C Na H antiporter NhaC
GKPIPPIE_01784 3.2e-49 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKPIPPIE_01785 2.3e-66 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GKPIPPIE_01786 1.7e-23 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GKPIPPIE_01787 2.1e-79 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GKPIPPIE_01788 1.4e-47 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GKPIPPIE_01790 1.6e-24 xerD D recombinase XerD
GKPIPPIE_01791 2e-36 xerD D recombinase XerD
GKPIPPIE_01792 5.2e-12 xerD D recombinase XerD
GKPIPPIE_01793 3.2e-25
GKPIPPIE_01794 2.2e-42 sip L Belongs to the 'phage' integrase family
GKPIPPIE_01795 6.5e-07
GKPIPPIE_01798 2.5e-29 M CHAP domain
GKPIPPIE_01800 2.9e-191 U type IV secretory pathway VirB4
GKPIPPIE_01801 6.6e-26
GKPIPPIE_01803 3.5e-76
GKPIPPIE_01804 7.6e-220 U TraM recognition site of TraD and TraG
GKPIPPIE_01808 9.7e-44 clpB O Belongs to the ClpA ClpB family
GKPIPPIE_01809 7.4e-99 clpB O Belongs to the ClpA ClpB family
GKPIPPIE_01812 2.2e-166 topA2 5.99.1.2 G Topoisomerase IA
GKPIPPIE_01813 1.8e-42 L Protein of unknown function (DUF3991)
GKPIPPIE_01814 2.7e-69
GKPIPPIE_01816 3.3e-60 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_01817 6.2e-38 V N-6 DNA Methylase
GKPIPPIE_01818 1.6e-164 V N-6 DNA Methylase
GKPIPPIE_01819 1.2e-22 S PIN domain
GKPIPPIE_01820 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
GKPIPPIE_01822 6.5e-90 pac DM Glucan-binding protein C
GKPIPPIE_01824 5.1e-94 L Belongs to the 'phage' integrase family
GKPIPPIE_01825 4.9e-07
GKPIPPIE_01826 1.4e-25 D nuclear chromosome segregation
GKPIPPIE_01828 3.7e-78 S Fic/DOC family
GKPIPPIE_01831 2.5e-60 ruvB 3.6.4.12 L four-way junction helicase activity
GKPIPPIE_01835 8.9e-55 tra L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
GKPIPPIE_01836 5e-53 L Helix-turn-helix domain
GKPIPPIE_01837 6e-82 L hmm pf00665
GKPIPPIE_01838 4.9e-19
GKPIPPIE_01839 1.2e-30 S Protein of unknown function (DUF3800)
GKPIPPIE_01842 4.7e-07
GKPIPPIE_01847 8.3e-20 S Replication initiator protein A (RepA) N-terminus
GKPIPPIE_01849 5.3e-09 S Arc-like DNA binding domain
GKPIPPIE_01851 5e-09
GKPIPPIE_01852 4.5e-12 K Helix-turn-helix XRE-family like proteins
GKPIPPIE_01853 7.8e-87 S Fic/DOC family
GKPIPPIE_01855 8.2e-16
GKPIPPIE_01856 1e-111 rssA S Phospholipase, patatin family
GKPIPPIE_01857 4.4e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKPIPPIE_01858 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
GKPIPPIE_01859 5.6e-45 S VIT family
GKPIPPIE_01860 4.2e-240 sufB O assembly protein SufB
GKPIPPIE_01861 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
GKPIPPIE_01862 1.2e-145 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKPIPPIE_01863 1.7e-144 sufD O FeS assembly protein SufD
GKPIPPIE_01864 3.6e-116 sufC O FeS assembly ATPase SufC
GKPIPPIE_01865 1.7e-224 E ABC transporter, substratebinding protein
GKPIPPIE_01866 5.2e-123 yfeO P Voltage gated chloride channel
GKPIPPIE_01867 1.1e-27 K Helix-turn-helix XRE-family like proteins
GKPIPPIE_01868 7.3e-136 pfoS S Phosphotransferase system, EIIC
GKPIPPIE_01869 4.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
GKPIPPIE_01870 6.3e-26 M Phage tail tape measure protein TP901
GKPIPPIE_01873 4.3e-07
GKPIPPIE_01878 1.7e-32 S Phage minor capsid protein 2
GKPIPPIE_01879 6.1e-99 fabK 1.3.1.9 S Nitronate monooxygenase
GKPIPPIE_01880 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GKPIPPIE_01882 1.3e-266 fbp 3.1.3.11 G phosphatase activity
GKPIPPIE_01883 1.1e-70 xerD L Phage integrase, N-terminal SAM-like domain
GKPIPPIE_01888 1.9e-56 K LytTr DNA-binding domain
GKPIPPIE_01889 8e-52 2.7.13.3 T GHKL domain
GKPIPPIE_01894 3.1e-16
GKPIPPIE_01896 4.2e-08
GKPIPPIE_01897 2e-39 blpT
GKPIPPIE_01898 2.3e-14
GKPIPPIE_01900 1.3e-186 mtnE 2.6.1.83 E Aminotransferase
GKPIPPIE_01901 3.8e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GKPIPPIE_01902 9.8e-67 S Protein of unknown function (DUF1440)
GKPIPPIE_01903 7.7e-41 S Iron-sulfur cluster assembly protein
GKPIPPIE_01904 6.1e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GKPIPPIE_01905 7.2e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GKPIPPIE_01906 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKPIPPIE_01907 7.8e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKPIPPIE_01908 4.7e-65 G Xylose isomerase domain protein TIM barrel
GKPIPPIE_01909 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
GKPIPPIE_01910 6.5e-90 nanK GK ROK family
GKPIPPIE_01911 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
GKPIPPIE_01912 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GKPIPPIE_01913 4.3e-75 K Helix-turn-helix domain, rpiR family
GKPIPPIE_01914 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
GKPIPPIE_01915 1.8e-217 yjeM E Amino Acid
GKPIPPIE_01917 2.8e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKPIPPIE_01918 6.2e-234 tetP J elongation factor G
GKPIPPIE_01919 6.1e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKPIPPIE_01920 6e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GKPIPPIE_01921 1.4e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GKPIPPIE_01922 2.8e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GKPIPPIE_01923 2.4e-181 gatC G PTS system sugar-specific permease component
GKPIPPIE_01924 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GKPIPPIE_01925 7.7e-34 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKPIPPIE_01926 1.7e-60 K DeoR C terminal sensor domain
GKPIPPIE_01927 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GKPIPPIE_01928 2.1e-77 S Fic/DOC family
GKPIPPIE_01929 4.1e-116 L PLD-like domain
GKPIPPIE_01930 9.5e-59 L PLD-like domain
GKPIPPIE_01933 3.2e-109 L Initiator Replication protein
GKPIPPIE_01934 4.3e-37 S Replication initiator protein A (RepA) N-terminus
GKPIPPIE_01935 5.9e-173 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GKPIPPIE_01936 4.2e-45 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GKPIPPIE_01937 6.1e-219 L Probable transposase
GKPIPPIE_01938 9.8e-21 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GKPIPPIE_01939 6.8e-39 licT K CAT RNA binding domain
GKPIPPIE_01940 4.2e-11 licT K transcriptional antiterminator
GKPIPPIE_01941 9.9e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
GKPIPPIE_01943 7.1e-35
GKPIPPIE_01944 0.0 pepN 3.4.11.2 E aminopeptidase
GKPIPPIE_01945 5.3e-12 2.7.13.3 T protein histidine kinase activity
GKPIPPIE_01946 8e-21 blpH 2.7.13.3 T protein histidine kinase activity
GKPIPPIE_01947 3e-35 agrA KT Response regulator of the LytR AlgR family
GKPIPPIE_01948 6.3e-20 M domain protein
GKPIPPIE_01951 1.8e-124 yvgN C Aldo keto reductase
GKPIPPIE_01952 3e-105 yraQ S Predicted permease
GKPIPPIE_01953 1.8e-62 yeeE S Sulphur transport
GKPIPPIE_01954 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
GKPIPPIE_01955 6.5e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
GKPIPPIE_01957 1.2e-234 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GKPIPPIE_01958 7.1e-26 S Psort location Cytoplasmic, score
GKPIPPIE_01959 7.6e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
GKPIPPIE_01960 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
GKPIPPIE_01961 1.6e-73 prdD S An automated process has identified a potential problem with this gene model
GKPIPPIE_01962 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GKPIPPIE_01963 7.8e-143 5.1.1.4 E Proline racemase
GKPIPPIE_01964 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
GKPIPPIE_01965 5.3e-223 ybeC E amino acid
GKPIPPIE_01966 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
GKPIPPIE_01967 2.2e-07 S Protein of unknown function (DUF3343)
GKPIPPIE_01968 1.1e-137 selB J Elongation factor SelB, winged helix
GKPIPPIE_01969 3.9e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
GKPIPPIE_01970 2.9e-108 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
GKPIPPIE_01971 9e-29 yitW S Iron-sulfur cluster assembly protein
GKPIPPIE_01972 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
GKPIPPIE_01973 9.2e-101 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
GKPIPPIE_01974 7.1e-148 yedE S Sulphur transport
GKPIPPIE_01975 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
GKPIPPIE_01977 3.4e-19 L Transposase DDE domain
GKPIPPIE_01978 1.8e-50 L Transposase DDE domain
GKPIPPIE_01979 2.6e-191 XK27_11280 S Psort location CytoplasmicMembrane, score
GKPIPPIE_01980 1.5e-10 L Plasmid pRiA4b ORF-3-like protein
GKPIPPIE_01981 2.4e-106 L Belongs to the 'phage' integrase family
GKPIPPIE_01982 3.7e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
GKPIPPIE_01983 4.3e-59 hsdM 2.1.1.72 V HsdM N-terminal domain
GKPIPPIE_01985 1.6e-165 L T/G mismatch-specific endonuclease activity
GKPIPPIE_01986 1.7e-61
GKPIPPIE_01987 3.2e-67
GKPIPPIE_01988 1e-57 yeeA V Type II restriction enzyme, methylase subunits
GKPIPPIE_01989 1.8e-14 yeeA V Type II restriction enzyme, methylase subunits
GKPIPPIE_01990 6.7e-212 yeeA V Type II restriction enzyme, methylase subunits
GKPIPPIE_01991 1.7e-255 yeeB L DEAD-like helicases superfamily
GKPIPPIE_01992 1.8e-93 pstS P T5orf172
GKPIPPIE_01993 3.6e-19
GKPIPPIE_01994 2.5e-16
GKPIPPIE_01997 5.8e-159 potE2 E amino acid
GKPIPPIE_01998 1.5e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GKPIPPIE_01999 3e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKPIPPIE_02000 7.3e-57 racA K Domain of unknown function (DUF1836)
GKPIPPIE_02001 1.1e-81 yitS S EDD domain protein, DegV family
GKPIPPIE_02002 3.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
GKPIPPIE_02004 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKPIPPIE_02005 0.0 O Belongs to the peptidase S8 family
GKPIPPIE_02006 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
GKPIPPIE_02007 9e-102 qmcA O prohibitin homologues
GKPIPPIE_02008 1.2e-52 1.14.12.17 C Oxidoreductase NAD-binding domain
GKPIPPIE_02009 9.5e-58 tlpA2 L Transposase IS200 like
GKPIPPIE_02010 5.7e-159 L transposase, IS605 OrfB family
GKPIPPIE_02011 3.2e-85 dps P Ferritin-like domain
GKPIPPIE_02012 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
GKPIPPIE_02013 1.7e-39 L hmm pf00665
GKPIPPIE_02014 4.8e-32 P Heavy-metal-associated domain
GKPIPPIE_02015 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GKPIPPIE_02016 1.3e-20 L PFAM transposase IS3 IS911 family protein
GKPIPPIE_02017 1.8e-41 L Integrase core domain
GKPIPPIE_02018 2.4e-35 L Integrase core domain
GKPIPPIE_02019 2.6e-129 EGP Major Facilitator Superfamily
GKPIPPIE_02020 7e-98 EGP Major Facilitator Superfamily
GKPIPPIE_02021 4.1e-71 K Transcriptional regulator, LysR family
GKPIPPIE_02022 4e-137 G Xylose isomerase-like TIM barrel
GKPIPPIE_02023 5e-116 IQ Enoyl-(Acyl carrier protein) reductase
GKPIPPIE_02024 1.6e-217 1.3.5.4 C FAD binding domain
GKPIPPIE_02025 3.5e-136 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKPIPPIE_02026 5.9e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GKPIPPIE_02027 3.2e-142 xerS L Phage integrase family
GKPIPPIE_02028 1.4e-32 S Domain of unknown function (DUF4417)
GKPIPPIE_02033 5.2e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GKPIPPIE_02034 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
GKPIPPIE_02035 5.6e-14 ptp3 3.1.3.48 T Tyrosine phosphatase family
GKPIPPIE_02036 6.7e-18 ptp3 3.1.3.48 T Tyrosine phosphatase family
GKPIPPIE_02037 2e-74 desR K helix_turn_helix, Lux Regulon
GKPIPPIE_02038 3.2e-57 salK 2.7.13.3 T Histidine kinase
GKPIPPIE_02039 1.9e-53 yvfS V ABC-2 type transporter
GKPIPPIE_02040 5.2e-79 yvfR V ABC transporter
GKPIPPIE_02041 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKPIPPIE_02042 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)