ORF_ID e_value Gene_name EC_number CAZy COGs Description
MANPEHPH_00001 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_00002 2.1e-41 H Beta-ketoacyl synthase, C-terminal domain
MANPEHPH_00003 2.8e-114 K WHG domain
MANPEHPH_00004 2.5e-110 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
MANPEHPH_00005 1.5e-19 2.3.1.1 K Psort location Cytoplasmic, score 8.87
MANPEHPH_00006 2.6e-91
MANPEHPH_00007 2e-166
MANPEHPH_00008 5.4e-152 L HNH endonuclease
MANPEHPH_00010 6.8e-45 L Transposase
MANPEHPH_00011 1.1e-97 tnp7109-21 L Integrase core domain
MANPEHPH_00012 1.4e-123 insK L Integrase core domain
MANPEHPH_00013 1.9e-66 L Helix-turn-helix domain
MANPEHPH_00014 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MANPEHPH_00015 1.1e-300 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MANPEHPH_00016 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
MANPEHPH_00017 4.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MANPEHPH_00019 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MANPEHPH_00020 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MANPEHPH_00021 7.8e-252 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MANPEHPH_00022 3.3e-214 ykiI
MANPEHPH_00023 6.5e-122
MANPEHPH_00025 5.6e-21 tag 3.2.2.20 L Methyladenine glycosylase
MANPEHPH_00026 3e-124 S GyrI-like small molecule binding domain
MANPEHPH_00027 9e-89 K Putative zinc ribbon domain
MANPEHPH_00028 6.4e-25 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MANPEHPH_00029 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MANPEHPH_00030 2.6e-126 3.6.1.13 L NUDIX domain
MANPEHPH_00031 5.1e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MANPEHPH_00032 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MANPEHPH_00033 2.8e-124 pdtaR T Response regulator receiver domain protein
MANPEHPH_00035 1.1e-109 aspA 3.6.1.13 L NUDIX domain
MANPEHPH_00036 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
MANPEHPH_00037 8e-177 terC P Integral membrane protein, TerC family
MANPEHPH_00038 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MANPEHPH_00039 1.6e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MANPEHPH_00040 3.2e-254 rpsA J Ribosomal protein S1
MANPEHPH_00041 4.9e-162 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MANPEHPH_00042 3e-183 P Zinc-uptake complex component A periplasmic
MANPEHPH_00043 1.1e-161 znuC P ATPases associated with a variety of cellular activities
MANPEHPH_00044 4e-137 znuB U ABC 3 transport family
MANPEHPH_00045 1.1e-87 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MANPEHPH_00046 2.1e-100 carD K CarD-like/TRCF domain
MANPEHPH_00047 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MANPEHPH_00048 1.3e-128 T Response regulator receiver domain protein
MANPEHPH_00049 4.4e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MANPEHPH_00050 1.9e-121 ctsW S Phosphoribosyl transferase domain
MANPEHPH_00051 5.4e-147 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MANPEHPH_00052 6.3e-78 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MANPEHPH_00053 2.5e-262
MANPEHPH_00054 0.0 S Glycosyl transferase, family 2
MANPEHPH_00055 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MANPEHPH_00056 1.3e-206 K Cell envelope-related transcriptional attenuator domain
MANPEHPH_00057 0.0 D FtsK/SpoIIIE family
MANPEHPH_00058 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MANPEHPH_00059 7.5e-280 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MANPEHPH_00060 1.2e-145 yplQ S Haemolysin-III related
MANPEHPH_00061 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MANPEHPH_00062 4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MANPEHPH_00063 1e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MANPEHPH_00064 2.9e-94
MANPEHPH_00066 2.9e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MANPEHPH_00067 6.3e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MANPEHPH_00068 6.6e-70 divIC D Septum formation initiator
MANPEHPH_00069 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MANPEHPH_00070 2.8e-168 1.1.1.65 C Aldo/keto reductase family
MANPEHPH_00071 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MANPEHPH_00072 1.5e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MANPEHPH_00073 1.6e-92 2.3.1.183 M Acetyltransferase (GNAT) domain
MANPEHPH_00074 0.0 S Uncharacterised protein family (UPF0182)
MANPEHPH_00075 8.5e-23 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MANPEHPH_00076 9.7e-92 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MANPEHPH_00077 9.2e-138 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MANPEHPH_00078 3e-96
MANPEHPH_00079 3.1e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MANPEHPH_00080 1.6e-282 thrC 4.2.3.1 E Threonine synthase N terminus
MANPEHPH_00081 4.8e-107
MANPEHPH_00082 3.8e-120 S ABC-2 family transporter protein
MANPEHPH_00083 1.1e-172 V ATPases associated with a variety of cellular activities
MANPEHPH_00084 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
MANPEHPH_00085 6.3e-18 J Acetyltransferase (GNAT) domain
MANPEHPH_00086 5.7e-21 G ABC transporter permease
MANPEHPH_00087 8.5e-57 G ABC transporter permease
MANPEHPH_00088 1.8e-170 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00089 3.2e-261 G Bacterial extracellular solute-binding protein
MANPEHPH_00090 0.0 cydD V ABC transporter transmembrane region
MANPEHPH_00092 1.7e-20 araE EGP Major facilitator Superfamily
MANPEHPH_00093 1.1e-40 araE EGP Major facilitator Superfamily
MANPEHPH_00094 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MANPEHPH_00095 1.9e-211 K helix_turn _helix lactose operon repressor
MANPEHPH_00096 5.3e-161 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MANPEHPH_00097 1.1e-164 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MANPEHPH_00098 6.2e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MANPEHPH_00100 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MANPEHPH_00101 6.8e-262 abcT3 P ATPases associated with a variety of cellular activities
MANPEHPH_00102 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MANPEHPH_00105 1.4e-176 S Auxin Efflux Carrier
MANPEHPH_00106 1.8e-136 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MANPEHPH_00107 1.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MANPEHPH_00108 8e-249 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MANPEHPH_00109 4.5e-117
MANPEHPH_00110 1.1e-77 soxR K MerR, DNA binding
MANPEHPH_00111 2.3e-195 yghZ C Aldo/keto reductase family
MANPEHPH_00112 2.4e-49 S Protein of unknown function (DUF3039)
MANPEHPH_00113 6e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MANPEHPH_00114 7.9e-87
MANPEHPH_00115 7.6e-117 yceD S Uncharacterized ACR, COG1399
MANPEHPH_00116 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MANPEHPH_00117 9.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MANPEHPH_00118 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MANPEHPH_00119 4e-93 ilvN 2.2.1.6 E ACT domain
MANPEHPH_00120 1.9e-43 stbC S Plasmid stability protein
MANPEHPH_00121 1.1e-71 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
MANPEHPH_00122 0.0 yjjK S ABC transporter
MANPEHPH_00123 6.4e-103 dam 2.1.1.72 H D12 class N6 adenine-specific DNA methyltransferase
MANPEHPH_00124 1.8e-112
MANPEHPH_00126 2e-136 guaA1 6.3.5.2 F Peptidase C26
MANPEHPH_00127 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MANPEHPH_00128 2.3e-162 P Cation efflux family
MANPEHPH_00129 7.9e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MANPEHPH_00130 8.4e-206 S Endonuclease/Exonuclease/phosphatase family
MANPEHPH_00131 7e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MANPEHPH_00132 1e-34 CP_0960 S Belongs to the UPF0109 family
MANPEHPH_00133 2.2e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MANPEHPH_00134 2.5e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MANPEHPH_00135 2.4e-169 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MANPEHPH_00136 3.1e-20
MANPEHPH_00137 6.4e-57 S Predicted membrane protein (DUF2207)
MANPEHPH_00138 3e-43 S Predicted membrane protein (DUF2207)
MANPEHPH_00139 3e-49 S Predicted membrane protein (DUF2207)
MANPEHPH_00140 1.9e-10 S Predicted membrane protein (DUF2207)
MANPEHPH_00141 0.0 S Predicted membrane protein (DUF2207)
MANPEHPH_00142 2.4e-88 lemA S LemA family
MANPEHPH_00143 5.1e-29 macB_7 V FtsX-like permease family
MANPEHPH_00144 4.2e-119 V ABC transporter, ATP-binding protein
MANPEHPH_00145 1.4e-123 insK L Integrase core domain
MANPEHPH_00146 1.9e-66 L Helix-turn-helix domain
MANPEHPH_00147 2.8e-295 L PFAM Integrase catalytic
MANPEHPH_00148 9.6e-147 L Transposase
MANPEHPH_00150 1.5e-244 S KAP family P-loop domain
MANPEHPH_00152 2.8e-37 L PFAM Integrase catalytic
MANPEHPH_00153 5.1e-07 L Transposase
MANPEHPH_00155 1.3e-35 L PFAM Integrase catalytic
MANPEHPH_00156 5.8e-32 L Transposase
MANPEHPH_00157 1e-237 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MANPEHPH_00158 3.6e-15 L Psort location Cytoplasmic, score 8.87
MANPEHPH_00159 0.0 E ABC transporter, substrate-binding protein, family 5
MANPEHPH_00160 1.2e-85 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
MANPEHPH_00161 6.2e-135 V ATPases associated with a variety of cellular activities
MANPEHPH_00162 9.1e-181 M Conserved repeat domain
MANPEHPH_00163 7.2e-286 macB_8 V MacB-like periplasmic core domain
MANPEHPH_00164 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MANPEHPH_00165 2.4e-181 adh3 C Zinc-binding dehydrogenase
MANPEHPH_00166 9.6e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MANPEHPH_00167 4.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MANPEHPH_00168 1.2e-68 zur P Belongs to the Fur family
MANPEHPH_00169 1e-79 ylbB V FtsX-like permease family
MANPEHPH_00170 1.2e-27 ylbB V FtsX-like permease family
MANPEHPH_00171 3.1e-70 XK27_06785 V ABC transporter
MANPEHPH_00172 7.1e-64
MANPEHPH_00173 1.1e-29 zur P Ferric uptake regulator family
MANPEHPH_00174 5e-139 S TIGRFAM TIGR03943 family protein
MANPEHPH_00175 1.8e-180 ycgR S Predicted permease
MANPEHPH_00176 1.8e-25 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MANPEHPH_00177 1.3e-18 J Ribosomal L32p protein family
MANPEHPH_00178 1.1e-14 rpmJ J Ribosomal protein L36
MANPEHPH_00179 4.4e-34 rpmE2 J Ribosomal protein L31
MANPEHPH_00180 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MANPEHPH_00181 1.4e-20 rpmG J Ribosomal protein L33
MANPEHPH_00182 3.9e-29 rpmB J Ribosomal L28 family
MANPEHPH_00183 5.8e-98 S cobalamin synthesis protein
MANPEHPH_00184 7.3e-156 P Zinc-uptake complex component A periplasmic
MANPEHPH_00185 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MANPEHPH_00186 1.9e-297 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MANPEHPH_00187 1.1e-242 purD 6.3.4.13 F Belongs to the GARS family
MANPEHPH_00188 9.2e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MANPEHPH_00189 2.7e-293 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MANPEHPH_00190 2.7e-299 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MANPEHPH_00191 2.3e-31
MANPEHPH_00192 1.2e-13 C Aldo/keto reductase family
MANPEHPH_00193 4.7e-102 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MANPEHPH_00194 1.3e-109 Q D-alanine [D-alanyl carrier protein] ligase activity
MANPEHPH_00195 5.5e-253 Q D-alanine [D-alanyl carrier protein] ligase activity
MANPEHPH_00196 9.9e-239 I alpha/beta hydrolase fold
MANPEHPH_00197 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MANPEHPH_00198 3.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MANPEHPH_00199 2.2e-222 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MANPEHPH_00200 1.1e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
MANPEHPH_00201 5.2e-220 M Glycosyl transferase 4-like domain
MANPEHPH_00202 5.2e-195 ltaE 4.1.2.48 E Beta-eliminating lyase
MANPEHPH_00204 6.6e-111 yocS S SBF-like CPA transporter family (DUF4137)
MANPEHPH_00205 2.1e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MANPEHPH_00206 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MANPEHPH_00207 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MANPEHPH_00208 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MANPEHPH_00209 3.5e-129 tmp1 S Domain of unknown function (DUF4391)
MANPEHPH_00210 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MANPEHPH_00211 1e-185 MA20_14895 S Conserved hypothetical protein 698
MANPEHPH_00212 6.3e-21 S Psort location CytoplasmicMembrane, score
MANPEHPH_00213 1.2e-28 S polysaccharide biosynthetic process
MANPEHPH_00214 1.3e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MANPEHPH_00215 1.7e-85 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MANPEHPH_00216 6.4e-67 K MerR family regulatory protein
MANPEHPH_00217 4.3e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MANPEHPH_00218 3.9e-259 S Domain of unknown function (DUF4143)
MANPEHPH_00219 9.9e-109 P Protein of unknown function DUF47
MANPEHPH_00220 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MANPEHPH_00221 4.4e-242 vbsD V MatE
MANPEHPH_00222 3.2e-124 magIII L endonuclease III
MANPEHPH_00224 5.7e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MANPEHPH_00225 6.4e-41 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MANPEHPH_00226 1e-185 S Membrane transport protein
MANPEHPH_00227 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
MANPEHPH_00229 0.0 M probably involved in cell wall
MANPEHPH_00230 3.8e-251 3.2.1.14 GH18 S Carbohydrate binding domain
MANPEHPH_00231 0.0 T Diguanylate cyclase, GGDEF domain
MANPEHPH_00232 7.1e-136 ybbM V Uncharacterised protein family (UPF0014)
MANPEHPH_00233 6.9e-130 ybbL V ATPases associated with a variety of cellular activities
MANPEHPH_00234 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MANPEHPH_00235 1.7e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MANPEHPH_00236 2.2e-240 carA 6.3.5.5 F Belongs to the CarA family
MANPEHPH_00237 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MANPEHPH_00238 2.6e-169 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MANPEHPH_00239 1.4e-104 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MANPEHPH_00240 8.3e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MANPEHPH_00242 0.0 tetP J Elongation factor G, domain IV
MANPEHPH_00243 8.7e-92 tetP J Elongation factor G, domain IV
MANPEHPH_00244 2.7e-126 ypfH S Phospholipase/Carboxylesterase
MANPEHPH_00245 4e-234 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MANPEHPH_00246 2.5e-42 XAC3035 O Glutaredoxin
MANPEHPH_00247 4.6e-176 S Domain of unknown function (DUF4143)
MANPEHPH_00248 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MANPEHPH_00249 3.6e-115 XK27_08050 O prohibitin homologues
MANPEHPH_00250 1.1e-58 S Domain of unknown function (DUF4143)
MANPEHPH_00251 1.4e-158 S Patatin-like phospholipase
MANPEHPH_00252 1.6e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MANPEHPH_00253 8.6e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MANPEHPH_00254 7.2e-127 S Vitamin K epoxide reductase
MANPEHPH_00255 5.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MANPEHPH_00256 4.7e-32 S Protein of unknown function (DUF3107)
MANPEHPH_00257 1.9e-300 mphA S Aminoglycoside phosphotransferase
MANPEHPH_00258 2.9e-290 uvrD2 3.6.4.12 L DNA helicase
MANPEHPH_00259 1e-296 S Zincin-like metallopeptidase
MANPEHPH_00260 1.5e-156 lon T Belongs to the peptidase S16 family
MANPEHPH_00261 1.6e-73 S Protein of unknown function (DUF3052)
MANPEHPH_00263 8.8e-210 2.7.11.1 NU Tfp pilus assembly protein FimV
MANPEHPH_00264 3.2e-220 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MANPEHPH_00265 5.3e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MANPEHPH_00266 0.0 I acetylesterase activity
MANPEHPH_00267 4.5e-129 recO L Involved in DNA repair and RecF pathway recombination
MANPEHPH_00268 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MANPEHPH_00269 4.5e-135 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_00270 2e-189 P NMT1/THI5 like
MANPEHPH_00271 9e-223 E Aminotransferase class I and II
MANPEHPH_00272 6.3e-140 bioM P ATPases associated with a variety of cellular activities
MANPEHPH_00274 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MANPEHPH_00275 0.0 S Tetratricopeptide repeat
MANPEHPH_00276 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MANPEHPH_00277 6e-205 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MANPEHPH_00278 5e-281 glnA 6.3.1.2 E glutamine synthetase
MANPEHPH_00279 9.2e-144 S Domain of unknown function (DUF4191)
MANPEHPH_00280 5.4e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MANPEHPH_00281 6.9e-102 S Protein of unknown function (DUF3043)
MANPEHPH_00282 6.1e-260 argE E Peptidase dimerisation domain
MANPEHPH_00283 6.2e-108 ykoE S ABC-type cobalt transport system, permease component
MANPEHPH_00284 3.4e-280 ykoD P ATPases associated with a variety of cellular activities
MANPEHPH_00285 1.2e-158 cbiQ P Cobalt transport protein
MANPEHPH_00286 6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MANPEHPH_00287 7.7e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MANPEHPH_00288 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MANPEHPH_00289 3.5e-88
MANPEHPH_00290 5e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MANPEHPH_00291 2.4e-212 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MANPEHPH_00292 8.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MANPEHPH_00293 3.5e-249 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MANPEHPH_00294 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MANPEHPH_00295 4.9e-83 argR K Regulates arginine biosynthesis genes
MANPEHPH_00296 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MANPEHPH_00297 2.7e-56 L PFAM Integrase catalytic
MANPEHPH_00298 7.4e-30 L PFAM Integrase catalytic
MANPEHPH_00299 8.5e-44 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
MANPEHPH_00300 2.4e-32 relB L RelB antitoxin
MANPEHPH_00301 4.4e-280 argH 4.3.2.1 E argininosuccinate lyase
MANPEHPH_00302 1.2e-28 thiS 2.8.1.10 H ThiS family
MANPEHPH_00303 3.6e-157 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MANPEHPH_00304 6e-146 moeB 2.7.7.80 H ThiF family
MANPEHPH_00305 3.1e-71 M1-798 P Rhodanese Homology Domain
MANPEHPH_00306 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MANPEHPH_00307 7.4e-138 S Putative ABC-transporter type IV
MANPEHPH_00308 1.2e-81 S Protein of unknown function (DUF975)
MANPEHPH_00309 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MANPEHPH_00310 1.9e-171 L Tetratricopeptide repeat
MANPEHPH_00311 9.3e-200 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MANPEHPH_00313 1.4e-139 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MANPEHPH_00314 4.7e-96
MANPEHPH_00315 4e-69 trkA P TrkA-N domain
MANPEHPH_00316 8.3e-12 trkB P Cation transport protein
MANPEHPH_00317 7.4e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MANPEHPH_00318 0.0 recN L May be involved in recombinational repair of damaged DNA
MANPEHPH_00319 5e-119 S Haloacid dehalogenase-like hydrolase
MANPEHPH_00320 6e-13 J Acetyltransferase (GNAT) domain
MANPEHPH_00321 9.6e-117 L Transposase
MANPEHPH_00322 1.4e-150 L IstB-like ATP binding protein
MANPEHPH_00324 1.6e-191 G Acyltransferase family
MANPEHPH_00325 5.9e-194 wzy S EpsG family
MANPEHPH_00327 5.8e-188 M Glycosyltransferase like family 2
MANPEHPH_00328 1e-212 S Polysaccharide pyruvyl transferase
MANPEHPH_00329 5.1e-133 H Hexapeptide repeat of succinyl-transferase
MANPEHPH_00330 8.3e-201 2.4.1.166 GT2 M Glycosyltransferase like family 2
MANPEHPH_00331 1.5e-253 cps2J S Polysaccharide biosynthesis protein
MANPEHPH_00332 6.8e-245 MA20_17390 GT4 M Glycosyl transferases group 1
MANPEHPH_00333 1.7e-207 GT4 M Psort location Cytoplasmic, score 8.87
MANPEHPH_00334 9.7e-109 3.1.3.48 T Low molecular weight phosphatase family
MANPEHPH_00335 7.2e-234 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MANPEHPH_00336 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MANPEHPH_00337 9.6e-281 EGP Major facilitator Superfamily
MANPEHPH_00338 8.9e-232 mntH P H( )-stimulated, divalent metal cation uptake system
MANPEHPH_00339 3.5e-140 L Protein of unknown function (DUF1524)
MANPEHPH_00340 2e-168 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MANPEHPH_00341 0.0 ganB 3.2.1.89 G Glycosyl hydrolase family 53
MANPEHPH_00342 5.5e-192 K helix_turn _helix lactose operon repressor
MANPEHPH_00343 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MANPEHPH_00344 3.4e-103 G ABC transporter permease
MANPEHPH_00345 0.0 H Beta-ketoacyl synthase, C-terminal domain
MANPEHPH_00346 0.0 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
MANPEHPH_00347 1.1e-265 EGP Major Facilitator Superfamily
MANPEHPH_00348 6.2e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MANPEHPH_00349 1.2e-79 XK27_10430 S NAD(P)H-binding
MANPEHPH_00350 2e-55 ydeP K HxlR-like helix-turn-helix
MANPEHPH_00351 2.2e-135 yoaK S Protein of unknown function (DUF1275)
MANPEHPH_00352 4.7e-69
MANPEHPH_00355 2.9e-295 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MANPEHPH_00357 2.4e-160 S Protein of unknown function (DUF805)
MANPEHPH_00358 5e-234 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MANPEHPH_00359 2.2e-118
MANPEHPH_00360 1.7e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MANPEHPH_00361 9.7e-248 EGP Major facilitator Superfamily
MANPEHPH_00362 8.4e-96 S GtrA-like protein
MANPEHPH_00363 3.3e-61 S Macrophage migration inhibitory factor (MIF)
MANPEHPH_00364 1.8e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MANPEHPH_00365 0.0 pepD E Peptidase family C69
MANPEHPH_00366 2.5e-106 S Phosphatidylethanolamine-binding protein
MANPEHPH_00367 3e-19 D nuclear chromosome segregation
MANPEHPH_00368 6.5e-31 3.4.17.14 M domain, Protein
MANPEHPH_00369 7.8e-294 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MANPEHPH_00371 3.3e-37 ptsH G PTS HPr component phosphorylation site
MANPEHPH_00372 2.3e-105 K helix_turn _helix lactose operon repressor
MANPEHPH_00373 7.8e-208 holB 2.7.7.7 L DNA polymerase III
MANPEHPH_00374 1.6e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MANPEHPH_00375 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MANPEHPH_00376 2.5e-166 3.6.1.27 I PAP2 superfamily
MANPEHPH_00377 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MANPEHPH_00378 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MANPEHPH_00379 6.8e-273 S Calcineurin-like phosphoesterase
MANPEHPH_00380 8.9e-16 S Calcineurin-like phosphoesterase
MANPEHPH_00381 1e-151 K FCD
MANPEHPH_00382 9.7e-244 P Domain of unknown function (DUF4143)
MANPEHPH_00383 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
MANPEHPH_00384 5.9e-13 nagA 3.5.1.25 G Amidohydrolase family
MANPEHPH_00385 1.2e-146 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MANPEHPH_00386 1.8e-178 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MANPEHPH_00387 5e-148 oppF E ATPases associated with a variety of cellular activities
MANPEHPH_00388 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
MANPEHPH_00389 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
MANPEHPH_00390 7.9e-304 E Bacterial extracellular solute-binding proteins, family 5 Middle
MANPEHPH_00391 2.1e-159 3.5.1.106 I carboxylic ester hydrolase activity
MANPEHPH_00392 1.3e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MANPEHPH_00393 6.3e-169 2.7.1.2 GK ROK family
MANPEHPH_00394 9.9e-174 L Domain of unknown function (DUF4862)
MANPEHPH_00395 9.6e-112
MANPEHPH_00396 9e-214 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MANPEHPH_00397 9.4e-98 askB 1.1.1.3, 2.7.2.4 E ACT domain
MANPEHPH_00398 2.9e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MANPEHPH_00399 5.7e-191 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MANPEHPH_00400 5.1e-34 V Abi-like protein
MANPEHPH_00401 1.5e-196 3.4.22.70 M Sortase family
MANPEHPH_00402 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MANPEHPH_00403 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MANPEHPH_00404 3.2e-96 K Bacterial regulatory proteins, tetR family
MANPEHPH_00405 2.9e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MANPEHPH_00406 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
MANPEHPH_00407 3.7e-58 U TadE-like protein
MANPEHPH_00408 1.1e-41 S Protein of unknown function (DUF4244)
MANPEHPH_00409 3.1e-116 gspF NU Type II secretion system (T2SS), protein F
MANPEHPH_00410 1.2e-74 U Type ii secretion system
MANPEHPH_00411 9.1e-192 cpaF U Type II IV secretion system protein
MANPEHPH_00412 5.8e-125 cpaE D bacterial-type flagellum organization
MANPEHPH_00413 1.6e-134 dedA S SNARE associated Golgi protein
MANPEHPH_00414 2.3e-127 S HAD hydrolase, family IA, variant 3
MANPEHPH_00415 1.1e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MANPEHPH_00416 1.5e-114 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
MANPEHPH_00417 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
MANPEHPH_00418 1.2e-103 hspR K transcriptional regulator, MerR family
MANPEHPH_00419 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
MANPEHPH_00420 1e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MANPEHPH_00421 0.0 dnaK O Heat shock 70 kDa protein
MANPEHPH_00422 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
MANPEHPH_00423 1.1e-194 K Psort location Cytoplasmic, score
MANPEHPH_00424 4.5e-146 traX S TraX protein
MANPEHPH_00425 1.2e-166 malG G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00426 5.1e-254 malF G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00427 1.7e-232 malE G Bacterial extracellular solute-binding protein
MANPEHPH_00428 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
MANPEHPH_00429 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MANPEHPH_00430 1e-173 3.4.22.70 M Sortase family
MANPEHPH_00431 0.0 M domain protein
MANPEHPH_00432 0.0 M cell wall anchor domain protein
MANPEHPH_00433 8.9e-187 K Psort location Cytoplasmic, score
MANPEHPH_00434 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MANPEHPH_00435 1.2e-191 K Transcriptional regulator
MANPEHPH_00436 8.1e-148 S Psort location Cytoplasmic, score
MANPEHPH_00437 4.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MANPEHPH_00438 1.5e-58 bioY S BioY family
MANPEHPH_00439 3e-72 cbiO P ATPases associated with a variety of cellular activities
MANPEHPH_00440 1.8e-51 bioN P Cobalt transport protein
MANPEHPH_00441 6.9e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MANPEHPH_00442 1.4e-251 yhjE EGP Sugar (and other) transporter
MANPEHPH_00443 4.8e-180 K helix_turn _helix lactose operon repressor
MANPEHPH_00444 5.9e-278 scrT G Transporter major facilitator family protein
MANPEHPH_00445 3e-300 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MANPEHPH_00447 1.9e-200 K helix_turn _helix lactose operon repressor
MANPEHPH_00448 1.9e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MANPEHPH_00449 1.9e-147 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MANPEHPH_00450 4.1e-281 clcA P Voltage gated chloride channel
MANPEHPH_00451 3.4e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MANPEHPH_00452 6.1e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MANPEHPH_00453 3e-173 yicL EG EamA-like transporter family
MANPEHPH_00455 1.5e-172 htpX O Belongs to the peptidase M48B family
MANPEHPH_00456 9e-278 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MANPEHPH_00457 0.0 cadA P E1-E2 ATPase
MANPEHPH_00458 8.4e-263 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MANPEHPH_00459 1e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MANPEHPH_00461 7e-145 yplQ S Haemolysin-III related
MANPEHPH_00462 7.8e-52 ybjQ S Putative heavy-metal-binding
MANPEHPH_00463 4.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MANPEHPH_00464 1.2e-123 KL Domain of unknown function (DUF3427)
MANPEHPH_00465 0.0 KL Domain of unknown function (DUF3427)
MANPEHPH_00466 8.3e-164 M Glycosyltransferase like family 2
MANPEHPH_00467 6.7e-198 S Fic/DOC family
MANPEHPH_00468 6.3e-131 S Pyridoxamine 5'-phosphate oxidase
MANPEHPH_00469 1.4e-200 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MANPEHPH_00470 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MANPEHPH_00471 6e-255 S Putative esterase
MANPEHPH_00472 1.1e-22
MANPEHPH_00473 1.2e-177 yddG EG EamA-like transporter family
MANPEHPH_00474 3.3e-86 hsp20 O Hsp20/alpha crystallin family
MANPEHPH_00475 7.5e-213 pldB 3.1.1.5 I Serine aminopeptidase, S33
MANPEHPH_00476 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MANPEHPH_00477 2e-129 fhaA T Protein of unknown function (DUF2662)
MANPEHPH_00478 3.9e-74 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MANPEHPH_00479 7.7e-270 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MANPEHPH_00480 6.9e-279 rodA D Belongs to the SEDS family
MANPEHPH_00481 4.1e-262 pbpA M penicillin-binding protein
MANPEHPH_00482 1e-173 T Protein tyrosine kinase
MANPEHPH_00483 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MANPEHPH_00484 2e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MANPEHPH_00485 3.2e-228 srtA 3.4.22.70 M Sortase family
MANPEHPH_00486 1.8e-118 S Bacterial protein of unknown function (DUF881)
MANPEHPH_00487 9.8e-69 crgA D Involved in cell division
MANPEHPH_00488 9.4e-122 gluP 3.4.21.105 S Rhomboid family
MANPEHPH_00489 2.6e-35
MANPEHPH_00490 1.8e-195 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MANPEHPH_00491 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_00492 3.8e-173 S Fic/DOC family
MANPEHPH_00493 2.4e-253 S HipA-like C-terminal domain
MANPEHPH_00495 2.3e-74
MANPEHPH_00496 6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MANPEHPH_00497 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MANPEHPH_00498 6.5e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MANPEHPH_00499 1.4e-47 S Domain of unknown function (DUF4193)
MANPEHPH_00500 1.3e-148 S Protein of unknown function (DUF3071)
MANPEHPH_00501 1.5e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
MANPEHPH_00502 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MANPEHPH_00504 5.2e-43 K Psort location Cytoplasmic, score
MANPEHPH_00505 1.2e-48 K Psort location Cytoplasmic, score
MANPEHPH_00506 0.0 lhr L DEAD DEAH box helicase
MANPEHPH_00507 1.7e-171 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MANPEHPH_00508 1e-221 G Major Facilitator Superfamily
MANPEHPH_00509 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MANPEHPH_00510 8.2e-191 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MANPEHPH_00511 1.4e-113
MANPEHPH_00512 2.9e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MANPEHPH_00513 0.0 pknL 2.7.11.1 KLT PASTA
MANPEHPH_00514 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
MANPEHPH_00515 5.3e-119
MANPEHPH_00516 1.1e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MANPEHPH_00517 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MANPEHPH_00518 2.4e-113 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MANPEHPH_00519 1.8e-102 recX S Modulates RecA activity
MANPEHPH_00520 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MANPEHPH_00521 1.2e-31 S Protein of unknown function (DUF3046)
MANPEHPH_00522 1.2e-78 K Helix-turn-helix XRE-family like proteins
MANPEHPH_00523 4.6e-97 cinA 3.5.1.42 S Belongs to the CinA family
MANPEHPH_00524 4.7e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MANPEHPH_00525 0.0 ftsK D FtsK SpoIIIE family protein
MANPEHPH_00526 7.8e-150 fic D Fic/DOC family
MANPEHPH_00527 2.5e-183 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MANPEHPH_00528 2.6e-277 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MANPEHPH_00529 5.2e-150 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MANPEHPH_00530 9.7e-164 ydeD EG EamA-like transporter family
MANPEHPH_00531 2.2e-135 ybhL S Belongs to the BI1 family
MANPEHPH_00532 5.2e-89 K helix_turn_helix, Lux Regulon
MANPEHPH_00533 6.8e-121 E Psort location Cytoplasmic, score 8.87
MANPEHPH_00534 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MANPEHPH_00535 0.0 ctpE P E1-E2 ATPase
MANPEHPH_00536 4.1e-96
MANPEHPH_00537 5.3e-242 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MANPEHPH_00538 3.8e-134 S Protein of unknown function (DUF3159)
MANPEHPH_00539 1.4e-153 S Protein of unknown function (DUF3710)
MANPEHPH_00540 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MANPEHPH_00541 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
MANPEHPH_00542 1.4e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
MANPEHPH_00543 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
MANPEHPH_00544 0.0 E ABC transporter, substrate-binding protein, family 5
MANPEHPH_00545 3.9e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MANPEHPH_00546 6.4e-148 V ABC transporter, ATP-binding protein
MANPEHPH_00547 0.0 MV MacB-like periplasmic core domain
MANPEHPH_00548 4.5e-42
MANPEHPH_00549 7.2e-189 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MANPEHPH_00550 2e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MANPEHPH_00551 3.6e-79
MANPEHPH_00552 0.0 typA T Elongation factor G C-terminus
MANPEHPH_00553 2e-106 K Virulence activator alpha C-term
MANPEHPH_00554 4.8e-137 V ATPases associated with a variety of cellular activities
MANPEHPH_00555 0.0 V FtsX-like permease family
MANPEHPH_00556 4.5e-19 naiP U Sugar (and other) transporter
MANPEHPH_00557 1.8e-237 iscS1 2.8.1.7 E Aminotransferase class-V
MANPEHPH_00558 3.8e-162 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MANPEHPH_00559 2.1e-296 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MANPEHPH_00560 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MANPEHPH_00561 3.4e-160 nrtR 3.6.1.55 F NUDIX hydrolase
MANPEHPH_00562 5.9e-115 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MANPEHPH_00563 3.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MANPEHPH_00564 3.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MANPEHPH_00565 4.1e-159 xerD D recombinase XerD
MANPEHPH_00566 1.2e-213 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MANPEHPH_00567 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MANPEHPH_00568 6.2e-25 rpmI J Ribosomal protein L35
MANPEHPH_00569 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MANPEHPH_00570 1.4e-15 S Spermine/spermidine synthase domain
MANPEHPH_00571 2.7e-50 S Spermine/spermidine synthase domain
MANPEHPH_00572 1.2e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MANPEHPH_00573 1.3e-196 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MANPEHPH_00574 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MANPEHPH_00575 3.7e-182 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MANPEHPH_00576 4.2e-191 galM 5.1.3.3 G Aldose 1-epimerase
MANPEHPH_00577 1.1e-188 galM 5.1.3.3 G Aldose 1-epimerase
MANPEHPH_00578 3.3e-52
MANPEHPH_00579 1.8e-136 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MANPEHPH_00580 7.6e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MANPEHPH_00581 6.9e-192 V Acetyltransferase (GNAT) domain
MANPEHPH_00582 2.8e-20 V Acetyltransferase (GNAT) domain
MANPEHPH_00583 1.6e-46 V Acetyltransferase (GNAT) domain
MANPEHPH_00584 0.0 smc D Required for chromosome condensation and partitioning
MANPEHPH_00585 2e-302 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MANPEHPH_00586 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MANPEHPH_00587 7.4e-97 3.6.1.55 F NUDIX domain
MANPEHPH_00588 6.5e-248 nagA 3.5.1.25 G Amidohydrolase family
MANPEHPH_00589 6.2e-151 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MANPEHPH_00590 8.1e-210 GK ROK family
MANPEHPH_00591 2e-151 2.7.1.2 GK ROK family
MANPEHPH_00592 5.1e-226 GK ROK family
MANPEHPH_00593 1.2e-168 2.7.1.4 G pfkB family carbohydrate kinase
MANPEHPH_00594 1.8e-99 G Major Facilitator Superfamily
MANPEHPH_00595 9.3e-86 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MANPEHPH_00596 7e-15
MANPEHPH_00597 2.5e-173 ftsQ 6.3.2.4 D Cell division protein FtsQ
MANPEHPH_00598 2.5e-286 murC 6.3.2.8 M Belongs to the MurCDEF family
MANPEHPH_00599 1.2e-219 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MANPEHPH_00600 1.5e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MANPEHPH_00601 5.1e-273 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MANPEHPH_00602 1.2e-205 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MANPEHPH_00603 2e-240 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MANPEHPH_00604 2e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MANPEHPH_00605 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MANPEHPH_00606 1.4e-67 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MANPEHPH_00607 5.1e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MANPEHPH_00608 1.3e-93 mraZ K Belongs to the MraZ family
MANPEHPH_00609 0.0 L DNA helicase
MANPEHPH_00610 7.5e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MANPEHPH_00612 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MANPEHPH_00613 7.4e-46 M Lysin motif
MANPEHPH_00614 6.9e-130 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MANPEHPH_00615 7.7e-161 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MANPEHPH_00616 1.7e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MANPEHPH_00617 7e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MANPEHPH_00618 7.5e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MANPEHPH_00619 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MANPEHPH_00620 2.5e-217 EGP Major facilitator Superfamily
MANPEHPH_00621 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MANPEHPH_00622 8.1e-279 S Uncharacterized protein conserved in bacteria (DUF2252)
MANPEHPH_00623 1.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MANPEHPH_00624 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MANPEHPH_00625 5e-99
MANPEHPH_00626 4.6e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MANPEHPH_00627 8.9e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MANPEHPH_00628 7.3e-253 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MANPEHPH_00629 1.1e-53 acyP 3.6.1.7 C Acylphosphatase
MANPEHPH_00630 1.1e-155 yvgN 1.1.1.346 S Aldo/keto reductase family
MANPEHPH_00631 0.0 2.4.1.230, 3.2.1.51 GH65,GH95 G Glycosyl hydrolase family 65, N-terminal domain
MANPEHPH_00632 1.3e-165 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MANPEHPH_00633 6e-154 S Amidohydrolase
MANPEHPH_00634 3.4e-146 IQ KR domain
MANPEHPH_00635 1.4e-166 4.2.1.68 M Enolase C-terminal domain-like
MANPEHPH_00636 9.2e-10
MANPEHPH_00637 3.6e-277 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MANPEHPH_00638 5.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MANPEHPH_00639 4.9e-142 cobB2 K Sir2 family
MANPEHPH_00640 9.2e-10
MANPEHPH_00641 2e-45 S AAA domain
MANPEHPH_00642 2e-24 L PFAM Integrase catalytic
MANPEHPH_00643 0.0 tetP J elongation factor G
MANPEHPH_00644 1.8e-208 L PFAM Integrase catalytic
MANPEHPH_00645 5.9e-41 S Psort location Cytoplasmic, score
MANPEHPH_00646 9.5e-239 yhjX EGP Major facilitator Superfamily
MANPEHPH_00647 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MANPEHPH_00648 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MANPEHPH_00649 1.6e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MANPEHPH_00650 1.1e-91 V Forkhead associated domain
MANPEHPH_00651 7.4e-127 S AAA ATPase domain
MANPEHPH_00652 1.1e-232 ytfL P Transporter associated domain
MANPEHPH_00653 5.6e-83 dps P Belongs to the Dps family
MANPEHPH_00654 1.5e-266 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00655 8.9e-187 K Periplasmic binding protein-like domain
MANPEHPH_00656 3e-254 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00657 5.9e-229 M Protein of unknown function (DUF2961)
MANPEHPH_00659 4.8e-116 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00660 2e-76 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00661 6.9e-72 K Psort location Cytoplasmic, score
MANPEHPH_00662 1.5e-30 K Psort location Cytoplasmic, score
MANPEHPH_00663 9e-11 K Psort location Cytoplasmic, score
MANPEHPH_00664 4.2e-150 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00665 5.8e-152 rafG G ABC transporter permease
MANPEHPH_00666 7e-75 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MANPEHPH_00667 4.1e-52 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MANPEHPH_00668 1e-147 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MANPEHPH_00669 4.5e-213 L Transposase and inactivated derivatives IS30 family
MANPEHPH_00670 3e-187 K Psort location Cytoplasmic, score
MANPEHPH_00671 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MANPEHPH_00672 5.9e-252 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00673 2.1e-292 3.2.1.26 GH32 G Glycosyl hydrolases family 32
MANPEHPH_00674 3.8e-201 K Periplasmic binding protein domain
MANPEHPH_00675 1e-114 S Protein of unknown function, DUF624
MANPEHPH_00676 2e-87 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_00677 3.6e-116 L Transposase and inactivated derivatives IS30 family
MANPEHPH_00678 3.3e-83 dps P Belongs to the Dps family
MANPEHPH_00679 3.6e-257 S Domain of unknown function (DUF4143)
MANPEHPH_00681 2e-22 L Transposase and inactivated derivatives IS30 family
MANPEHPH_00682 2.3e-10 L Transposase and inactivated derivatives IS30 family
MANPEHPH_00683 1.3e-13 relB L RelB antitoxin
MANPEHPH_00684 9.5e-181 2.1.1.72, 3.1.21.3, 3.1.21.4 L N-6 DNA methylase
MANPEHPH_00685 6.8e-87 S AAA domain
MANPEHPH_00686 2.5e-60 2.7.11.1 KLT Protein tyrosine kinase
MANPEHPH_00688 3.5e-78 S Putative inner membrane protein (DUF1819)
MANPEHPH_00689 2.5e-22 CP_1020 S zinc ion binding
MANPEHPH_00691 5.2e-178 I alpha/beta hydrolase fold
MANPEHPH_00692 2.5e-89 S Appr-1'-p processing enzyme
MANPEHPH_00693 2.1e-145 S phosphoesterase or phosphohydrolase
MANPEHPH_00694 2.6e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MANPEHPH_00696 3e-133 S Phospholipase/Carboxylesterase
MANPEHPH_00697 7.8e-202 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MANPEHPH_00698 2.4e-98 sixA 3.6.1.55 T Phosphoglycerate mutase family
MANPEHPH_00700 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MANPEHPH_00701 5.7e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MANPEHPH_00702 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MANPEHPH_00703 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MANPEHPH_00704 8.3e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MANPEHPH_00705 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MANPEHPH_00706 3.3e-291 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MANPEHPH_00707 7.7e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MANPEHPH_00708 7.6e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MANPEHPH_00709 1.2e-180 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MANPEHPH_00710 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MANPEHPH_00711 3.5e-28
MANPEHPH_00712 7.3e-219 MA20_36090 S Psort location Cytoplasmic, score 8.87
MANPEHPH_00713 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MANPEHPH_00714 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MANPEHPH_00715 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MANPEHPH_00716 3.7e-301 ybiT S ABC transporter
MANPEHPH_00717 1.4e-130 S Enoyl-(Acyl carrier protein) reductase
MANPEHPH_00718 2.3e-130 P ABC transporter
MANPEHPH_00719 3.5e-24 XK26_04485 P Cobalt transport protein
MANPEHPH_00720 1.2e-14 XK26_04485 P Cobalt transport protein
MANPEHPH_00721 2.6e-33 XK26_04485 P Cobalt transport protein
MANPEHPH_00722 1.1e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MANPEHPH_00723 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MANPEHPH_00724 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MANPEHPH_00725 5.6e-191 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MANPEHPH_00726 5.4e-178 rapZ S Displays ATPase and GTPase activities
MANPEHPH_00727 3.5e-169 whiA K May be required for sporulation
MANPEHPH_00728 3.2e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MANPEHPH_00729 3.5e-146 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MANPEHPH_00730 2.5e-34 secG U Preprotein translocase SecG subunit
MANPEHPH_00731 1.9e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MANPEHPH_00732 1.4e-158 S Sucrose-6F-phosphate phosphohydrolase
MANPEHPH_00733 1e-300 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MANPEHPH_00734 3.2e-188
MANPEHPH_00735 5.4e-237 brnQ U Component of the transport system for branched-chain amino acids
MANPEHPH_00736 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MANPEHPH_00737 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MANPEHPH_00738 4.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MANPEHPH_00739 2.6e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MANPEHPH_00740 6.2e-156 G Fructosamine kinase
MANPEHPH_00741 1.8e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MANPEHPH_00742 1.2e-133 S PAC2 family
MANPEHPH_00748 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MANPEHPH_00749 3.1e-112 hit 2.7.7.53 FG HIT domain
MANPEHPH_00750 2e-111 yebC K transcriptional regulatory protein
MANPEHPH_00751 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MANPEHPH_00752 3.3e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MANPEHPH_00753 9.4e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MANPEHPH_00754 1.2e-52 yajC U Preprotein translocase subunit
MANPEHPH_00755 2.3e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MANPEHPH_00756 1.2e-222 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MANPEHPH_00757 9.3e-164 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MANPEHPH_00758 2.4e-229
MANPEHPH_00759 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MANPEHPH_00760 4.8e-32
MANPEHPH_00761 2.9e-120 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MANPEHPH_00762 1.2e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MANPEHPH_00763 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MANPEHPH_00765 1.5e-77 supH S Sucrose-6F-phosphate phosphohydrolase
MANPEHPH_00766 2.3e-74 supH S Sucrose-6F-phosphate phosphohydrolase
MANPEHPH_00767 2.4e-294 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MANPEHPH_00768 0.0 pafB K WYL domain
MANPEHPH_00769 6.8e-53
MANPEHPH_00770 0.0 helY L DEAD DEAH box helicase
MANPEHPH_00771 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MANPEHPH_00772 2.8e-139 pgp 3.1.3.18 S HAD-hyrolase-like
MANPEHPH_00773 6.9e-36
MANPEHPH_00774 4.9e-64
MANPEHPH_00775 2.6e-112 K helix_turn_helix, mercury resistance
MANPEHPH_00776 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
MANPEHPH_00777 6.5e-140 S Bacterial protein of unknown function (DUF881)
MANPEHPH_00778 3.9e-35 sbp S Protein of unknown function (DUF1290)
MANPEHPH_00779 1.7e-171 S Bacterial protein of unknown function (DUF881)
MANPEHPH_00780 1.2e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MANPEHPH_00781 3e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MANPEHPH_00782 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MANPEHPH_00783 9.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MANPEHPH_00784 5.3e-186 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MANPEHPH_00785 2.1e-160 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MANPEHPH_00786 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MANPEHPH_00787 1.2e-131 S SOS response associated peptidase (SRAP)
MANPEHPH_00788 3.6e-157 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MANPEHPH_00789 1.1e-259 mmuP E amino acid
MANPEHPH_00790 1.9e-50 EGP Major facilitator Superfamily
MANPEHPH_00791 2.9e-190 V VanZ like family
MANPEHPH_00792 1.6e-66 cefD 5.1.1.17 E Aminotransferase, class V
MANPEHPH_00793 3.3e-100 S Acetyltransferase (GNAT) domain
MANPEHPH_00794 1.5e-50
MANPEHPH_00795 5.2e-121
MANPEHPH_00798 2.9e-21 K helix_turn_helix, Lux Regulon
MANPEHPH_00799 4.5e-20 2.7.13.3 T Histidine kinase
MANPEHPH_00800 1.1e-193 2.7.13.3 T Histidine kinase
MANPEHPH_00801 6.3e-99 K helix_turn_helix, Lux Regulon
MANPEHPH_00802 3e-95
MANPEHPH_00803 3.6e-144 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MANPEHPH_00804 1.9e-124 lolD Q ATPases associated with a variety of cellular activities
MANPEHPH_00805 1.1e-177 V MacB-like periplasmic core domain
MANPEHPH_00806 9.3e-40 relB L RelB antitoxin
MANPEHPH_00807 1.1e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MANPEHPH_00808 8.4e-26 2.7.13.3 T Histidine kinase
MANPEHPH_00809 8e-94 rpoE4 K Sigma-70 region 2
MANPEHPH_00810 9.4e-22 S Psort location CytoplasmicMembrane, score
MANPEHPH_00811 6.1e-106
MANPEHPH_00812 1.7e-137
MANPEHPH_00813 2e-163 yfiL V ATPases associated with a variety of cellular activities
MANPEHPH_00814 6.9e-71
MANPEHPH_00815 1.6e-61
MANPEHPH_00816 4.5e-147 S EamA-like transporter family
MANPEHPH_00817 4.7e-98
MANPEHPH_00818 5e-128
MANPEHPH_00819 4.1e-121 V ATPases associated with a variety of cellular activities
MANPEHPH_00820 8.8e-16 fic D Fic/DOC family
MANPEHPH_00821 4.1e-23
MANPEHPH_00822 7.9e-109
MANPEHPH_00823 1.3e-45 K sequence-specific DNA binding
MANPEHPH_00824 3.4e-53 hipA 2.7.11.1 S kinase activity
MANPEHPH_00825 4.4e-42 2.6.1.76 EGP Major Facilitator Superfamily
MANPEHPH_00826 6.3e-20 G Major facilitator Superfamily
MANPEHPH_00827 1.4e-295 mmuP E amino acid
MANPEHPH_00829 1e-62 yeaO K Protein of unknown function, DUF488
MANPEHPH_00830 2.9e-75
MANPEHPH_00831 5e-174 3.6.4.12
MANPEHPH_00832 4e-65 yijF S Domain of unknown function (DUF1287)
MANPEHPH_00833 9.9e-299 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MANPEHPH_00834 5.3e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MANPEHPH_00835 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MANPEHPH_00836 8.7e-72 3.5.1.124 S DJ-1/PfpI family
MANPEHPH_00837 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MANPEHPH_00838 1.8e-173 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MANPEHPH_00839 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MANPEHPH_00840 2.8e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MANPEHPH_00841 1.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MANPEHPH_00842 5.8e-144 rpsB J Belongs to the universal ribosomal protein uS2 family
MANPEHPH_00843 2.2e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MANPEHPH_00844 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MANPEHPH_00845 3.3e-91
MANPEHPH_00846 7.6e-208 guaB 1.1.1.205 F IMP dehydrogenase family protein
MANPEHPH_00847 4.6e-243 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MANPEHPH_00848 7.8e-257 G ABC transporter substrate-binding protein
MANPEHPH_00849 2.4e-36 M Peptidase family M23
MANPEHPH_00851 5.4e-34 xerH L Phage integrase family
MANPEHPH_00852 3.4e-20 2.7.11.1 S HipA-like C-terminal domain
MANPEHPH_00854 4e-139 S Fic/DOC family
MANPEHPH_00855 4e-94 L PFAM Relaxase mobilization nuclease family protein
MANPEHPH_00856 7.4e-200 V AAA domain, putative AbiEii toxin, Type IV TA system
MANPEHPH_00857 1.9e-142 S ABC-2 family transporter protein
MANPEHPH_00858 8.9e-140
MANPEHPH_00859 6.7e-60
MANPEHPH_00861 3.3e-239 T Histidine kinase
MANPEHPH_00862 3.6e-120 K helix_turn_helix, Lux Regulon
MANPEHPH_00864 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MANPEHPH_00865 1e-105 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MANPEHPH_00866 1e-159 yeaZ 2.3.1.234 O Glycoprotease family
MANPEHPH_00867 4e-88 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MANPEHPH_00868 3.4e-172 holA 2.7.7.7 L DNA polymerase III delta subunit
MANPEHPH_00869 3.5e-310 comE S Competence protein
MANPEHPH_00870 1.6e-44 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MANPEHPH_00871 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MANPEHPH_00872 5.5e-161 ET Bacterial periplasmic substrate-binding proteins
MANPEHPH_00873 1e-168 corA P CorA-like Mg2+ transporter protein
MANPEHPH_00874 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MANPEHPH_00875 7.2e-231 L ribosomal rna small subunit methyltransferase
MANPEHPH_00876 1e-69 pdxH S Pfam:Pyridox_oxidase
MANPEHPH_00877 2.4e-170 EG EamA-like transporter family
MANPEHPH_00878 2.1e-131 C Putative TM nitroreductase
MANPEHPH_00879 3.8e-32
MANPEHPH_00881 3.3e-255 S Metal-independent alpha-mannosidase (GH125)
MANPEHPH_00882 7.8e-238 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MANPEHPH_00883 1.6e-202 K helix_turn _helix lactose operon repressor
MANPEHPH_00884 1.9e-72 G Glycosyl hydrolase family 85
MANPEHPH_00885 1.3e-132 G Glycosyl hydrolase family 85
MANPEHPH_00886 2.1e-281 G Glycosyl hydrolase family 85
MANPEHPH_00887 1.9e-54 tnp3512a L Transposase
MANPEHPH_00888 2.2e-14 G Glycosyl hydrolase family 85
MANPEHPH_00889 2.3e-176 endOF2 3.2.1.14, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
MANPEHPH_00890 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
MANPEHPH_00891 7e-258 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MANPEHPH_00892 3.9e-156 lacG G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00893 1.2e-169 G Binding-protein-dependent transport system inner membrane component
MANPEHPH_00894 3.5e-249 srrA1 G Bacterial extracellular solute-binding protein
MANPEHPH_00895 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
MANPEHPH_00896 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
MANPEHPH_00897 6.1e-16 L Phage integrase family
MANPEHPH_00898 1.2e-91 G ABC transporter permease
MANPEHPH_00899 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MANPEHPH_00900 2.5e-258 G Bacterial extracellular solute-binding protein
MANPEHPH_00901 4e-278 G Bacterial extracellular solute-binding protein
MANPEHPH_00902 9.1e-144 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MANPEHPH_00903 5.2e-290 E ABC transporter, substrate-binding protein, family 5
MANPEHPH_00904 1.3e-166 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_00905 1.1e-146 EP Binding-protein-dependent transport system inner membrane component
MANPEHPH_00906 6.5e-137 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MANPEHPH_00907 3.8e-137 sapF E ATPases associated with a variety of cellular activities
MANPEHPH_00908 9.7e-194 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MANPEHPH_00909 4.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MANPEHPH_00910 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MANPEHPH_00911 8e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MANPEHPH_00912 6.5e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MANPEHPH_00913 4.3e-272 yhdG E aromatic amino acid transport protein AroP K03293
MANPEHPH_00914 4.1e-264 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MANPEHPH_00915 6.8e-245 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MANPEHPH_00916 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MANPEHPH_00917 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MANPEHPH_00918 1.1e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MANPEHPH_00919 1.1e-294 EK Alanine-glyoxylate amino-transferase
MANPEHPH_00920 9.4e-209 ybiR P Citrate transporter
MANPEHPH_00921 3.3e-30
MANPEHPH_00922 7e-43 G Alpha-L-arabinofuranosidase C-terminal domain
MANPEHPH_00923 1.5e-158 K Helix-turn-helix domain, rpiR family
MANPEHPH_00926 5.2e-256 G Bacterial extracellular solute-binding protein
MANPEHPH_00927 8.4e-224 K helix_turn _helix lactose operon repressor
MANPEHPH_00928 6.2e-50 S LPXTG-motif cell wall anchor domain protein
MANPEHPH_00929 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
MANPEHPH_00930 6e-137 K UTRA domain
MANPEHPH_00931 1.1e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MANPEHPH_00932 1.4e-44 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MANPEHPH_00933 3.6e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MANPEHPH_00934 3.6e-221 2.4.1.166 GT2 M Glycosyltransferase like family 2
MANPEHPH_00935 5.1e-142 K LytTr DNA-binding domain
MANPEHPH_00936 3.2e-229 T GHKL domain
MANPEHPH_00937 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MANPEHPH_00939 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MANPEHPH_00940 1.2e-88 nrdI F Probably involved in ribonucleotide reductase function
MANPEHPH_00941 3.1e-43 nrdH O Glutaredoxin
MANPEHPH_00942 2.8e-122 S Psort location CytoplasmicMembrane, score
MANPEHPH_00943 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
MANPEHPH_00944 7e-121 K Helix-turn-helix XRE-family like proteins
MANPEHPH_00945 2.5e-27 T LytTr DNA-binding domain
MANPEHPH_00946 8.8e-34 T LytTr DNA-binding domain
MANPEHPH_00947 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
MANPEHPH_00948 0.0 KLT Protein tyrosine kinase
MANPEHPH_00949 7.5e-135 O Thioredoxin
MANPEHPH_00951 4.5e-216 S G5
MANPEHPH_00952 6.4e-168 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MANPEHPH_00953 2.2e-176 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MANPEHPH_00954 7e-110 S LytR cell envelope-related transcriptional attenuator
MANPEHPH_00955 9.2e-283 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MANPEHPH_00956 2.8e-166 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MANPEHPH_00957 0.0
MANPEHPH_00958 0.0 murJ KLT MviN-like protein
MANPEHPH_00959 7e-176 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MANPEHPH_00960 4.5e-225 parB K Belongs to the ParB family
MANPEHPH_00961 2.1e-174 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MANPEHPH_00962 3.4e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MANPEHPH_00963 1.5e-92 jag S Putative single-stranded nucleic acids-binding domain
MANPEHPH_00964 5.8e-183 yidC U Membrane protein insertase, YidC Oxa1 family
MANPEHPH_00965 2.9e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MANPEHPH_00966 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MANPEHPH_00967 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MANPEHPH_00968 1.9e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MANPEHPH_00969 3.8e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MANPEHPH_00970 4.2e-83 S Protein of unknown function (DUF721)
MANPEHPH_00971 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MANPEHPH_00972 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MANPEHPH_00973 3.2e-50 S Transmembrane domain of unknown function (DUF3566)
MANPEHPH_00974 1.5e-183 lacR K Transcriptional regulator, LacI family
MANPEHPH_00975 1.3e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
MANPEHPH_00976 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MANPEHPH_00977 1.1e-206 V VanZ like family
MANPEHPH_00979 1.1e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MANPEHPH_00980 6.3e-198 S Psort location CytoplasmicMembrane, score
MANPEHPH_00983 1.5e-123 S Protein of unknown function DUF45
MANPEHPH_00984 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_00985 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_00986 1e-38 L Transposase and inactivated derivatives IS30 family
MANPEHPH_00988 1.8e-142
MANPEHPH_00989 2.3e-93 bcp 1.11.1.15 O Redoxin
MANPEHPH_00990 2.1e-157 S Sucrose-6F-phosphate phosphohydrolase
MANPEHPH_00991 8.4e-159 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MANPEHPH_00992 1.6e-243 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MANPEHPH_00993 1.7e-81
MANPEHPH_00994 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MANPEHPH_00995 0.0 E ABC transporter, substrate-binding protein, family 5
MANPEHPH_00996 3e-300 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MANPEHPH_00997 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MANPEHPH_00998 9e-64 K helix_turn _helix lactose operon repressor
MANPEHPH_00999 1e-190 K helix_turn _helix lactose operon repressor
MANPEHPH_01001 7.4e-255 hemN H Involved in the biosynthesis of porphyrin-containing compound
MANPEHPH_01002 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MANPEHPH_01003 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
MANPEHPH_01004 3.3e-138 S UPF0126 domain
MANPEHPH_01005 2.9e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
MANPEHPH_01006 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
MANPEHPH_01007 1.7e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MANPEHPH_01008 1.4e-234 yhjX EGP Major facilitator Superfamily
MANPEHPH_01009 1.5e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MANPEHPH_01010 2.1e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MANPEHPH_01011 4.8e-197 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MANPEHPH_01012 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MANPEHPH_01013 4.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MANPEHPH_01014 5.6e-248 corC S CBS domain
MANPEHPH_01015 4.7e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MANPEHPH_01016 5.5e-217 phoH T PhoH-like protein
MANPEHPH_01017 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MANPEHPH_01018 3.5e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MANPEHPH_01020 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
MANPEHPH_01021 6.2e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MANPEHPH_01022 3.2e-109 yitW S Iron-sulfur cluster assembly protein
MANPEHPH_01023 8.1e-102 iscU C SUF system FeS assembly protein, NifU family
MANPEHPH_01024 1.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MANPEHPH_01025 7e-144 sufC O FeS assembly ATPase SufC
MANPEHPH_01026 1.1e-236 sufD O FeS assembly protein SufD
MANPEHPH_01027 1.5e-291 sufB O FeS assembly protein SufB
MANPEHPH_01028 4.5e-311 S L,D-transpeptidase catalytic domain
MANPEHPH_01029 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MANPEHPH_01030 4.1e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MANPEHPH_01031 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MANPEHPH_01032 2.3e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MANPEHPH_01033 5.3e-70 3.4.23.43 S Type IV leader peptidase family
MANPEHPH_01034 5.4e-196 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MANPEHPH_01035 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MANPEHPH_01036 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MANPEHPH_01037 1.6e-35
MANPEHPH_01038 2.4e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MANPEHPH_01039 1.9e-129 pgm3 G Phosphoglycerate mutase family
MANPEHPH_01040 2.7e-48 relB L RelB antitoxin
MANPEHPH_01041 7.1e-67 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MANPEHPH_01042 1.2e-111 E Transglutaminase-like superfamily
MANPEHPH_01043 1.8e-46 sdpI S SdpI/YhfL protein family
MANPEHPH_01044 2.5e-91 3.5.4.5 F cytidine deaminase activity
MANPEHPH_01045 4.4e-154 S Peptidase C26
MANPEHPH_01046 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MANPEHPH_01047 5.7e-153 lolD V ABC transporter
MANPEHPH_01048 1e-218 V FtsX-like permease family
MANPEHPH_01049 3.4e-62 S Domain of unknown function (DUF4418)
MANPEHPH_01050 0.0 pcrA 3.6.4.12 L DNA helicase
MANPEHPH_01051 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MANPEHPH_01052 8.8e-243 pbuX F Permease family
MANPEHPH_01053 2.8e-31 yozG K Cro/C1-type HTH DNA-binding domain
MANPEHPH_01054 1.1e-40 S Protein of unknown function (DUF2975)
MANPEHPH_01055 1.4e-158 I Serine aminopeptidase, S33
MANPEHPH_01056 7.3e-164 M pfam nlp p60
MANPEHPH_01057 4.3e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MANPEHPH_01058 5.3e-110 3.4.13.21 E Peptidase family S51
MANPEHPH_01059 1.9e-196
MANPEHPH_01060 3.2e-112 E GDSL-like Lipase/Acylhydrolase family
MANPEHPH_01061 1.7e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MANPEHPH_01062 4.3e-248 V ABC-2 family transporter protein
MANPEHPH_01063 7.5e-225 V ABC-2 family transporter protein
MANPEHPH_01064 1.3e-187 V ATPases associated with a variety of cellular activities
MANPEHPH_01065 3.9e-120 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MANPEHPH_01066 3.9e-243 T Histidine kinase
MANPEHPH_01067 8.3e-114 K helix_turn_helix, Lux Regulon
MANPEHPH_01068 2.1e-114 MA20_27875 P Protein of unknown function DUF47
MANPEHPH_01069 2.2e-188 pit P Phosphate transporter family
MANPEHPH_01070 1.4e-242 nplT G Alpha amylase, catalytic domain
MANPEHPH_01071 2.7e-304 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MANPEHPH_01072 1.2e-233 rutG F Permease family
MANPEHPH_01073 3e-161 3.1.3.73 G Phosphoglycerate mutase family
MANPEHPH_01074 1.3e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
MANPEHPH_01075 1.1e-232 EGP Major facilitator Superfamily
MANPEHPH_01077 2.2e-60 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MANPEHPH_01078 8.9e-94 S Sulfite exporter TauE/SafE
MANPEHPH_01079 2.9e-57 L Helix-turn-helix domain
MANPEHPH_01080 3.2e-107 S Sulfite exporter TauE/SafE
MANPEHPH_01081 8.9e-272 aslB C Iron-sulfur cluster-binding domain
MANPEHPH_01082 0.0 P Domain of unknown function (DUF4976)
MANPEHPH_01083 9.9e-253 gtr U Sugar (and other) transporter
MANPEHPH_01084 6.4e-159 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MANPEHPH_01085 3.1e-220 GK ROK family
MANPEHPH_01086 8.7e-176 2.7.1.2 GK ROK family
MANPEHPH_01087 1.9e-147 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MANPEHPH_01088 2.8e-243 nagA 3.5.1.25 G Amidohydrolase family
MANPEHPH_01089 9.1e-195 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MANPEHPH_01090 1.2e-13 EGP Transmembrane secretion effector
MANPEHPH_01091 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MANPEHPH_01092 2.2e-11
MANPEHPH_01093 1e-117 K Bacterial regulatory proteins, tetR family
MANPEHPH_01094 5.7e-220 G Transmembrane secretion effector
MANPEHPH_01095 1.3e-33 K addiction module antidote protein HigA
MANPEHPH_01096 3.3e-244 S HipA-like C-terminal domain
MANPEHPH_01097 1.1e-37 L RelB antitoxin
MANPEHPH_01098 2.9e-51 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MANPEHPH_01099 3.5e-66 S Cupin 2, conserved barrel domain protein
MANPEHPH_01100 1.3e-159 ksgA 2.1.1.182 J Methyltransferase domain
MANPEHPH_01101 1.1e-60 yccF S Inner membrane component domain
MANPEHPH_01102 1.1e-234 XK27_00240 K Fic/DOC family
MANPEHPH_01103 1.6e-14 2.7.7.7 L Transposase, Mutator family
MANPEHPH_01104 1.3e-204 drrC L ABC transporter
MANPEHPH_01105 0.0 4.2.1.53 S MCRA family
MANPEHPH_01106 4.6e-168 dkgA 1.1.1.346 C Aldo/keto reductase family
MANPEHPH_01107 3e-34 yneG S Domain of unknown function (DUF4186)
MANPEHPH_01108 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MANPEHPH_01109 1.7e-201 K WYL domain
MANPEHPH_01110 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MANPEHPH_01111 5.4e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MANPEHPH_01112 5.2e-22 tccB2 V DivIVA protein
MANPEHPH_01113 4.9e-45 yggT S YGGT family
MANPEHPH_01114 5.9e-69 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MANPEHPH_01115 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MANPEHPH_01116 1.7e-248 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MANPEHPH_01117 6.7e-297 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MANPEHPH_01118 4.1e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MANPEHPH_01119 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MANPEHPH_01120 1.3e-226 O AAA domain (Cdc48 subfamily)
MANPEHPH_01121 8.7e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MANPEHPH_01122 5.6e-62 S Thiamine-binding protein
MANPEHPH_01123 2.7e-247 ydjK G Sugar (and other) transporter
MANPEHPH_01124 1.2e-213 2.7.13.3 T Histidine kinase
MANPEHPH_01125 6.1e-123 K helix_turn_helix, Lux Regulon
MANPEHPH_01126 1.1e-189
MANPEHPH_01127 1e-257 O SERine Proteinase INhibitors
MANPEHPH_01128 1.8e-195 K helix_turn _helix lactose operon repressor
MANPEHPH_01129 1.4e-240 lacY P LacY proton/sugar symporter
MANPEHPH_01130 3.5e-304 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MANPEHPH_01131 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MANPEHPH_01132 5.8e-146 C Putative TM nitroreductase
MANPEHPH_01133 6.4e-198 S Glycosyltransferase, group 2 family protein
MANPEHPH_01134 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MANPEHPH_01135 0.0 ecfA GP ABC transporter, ATP-binding protein
MANPEHPH_01136 7e-47 yhbY J CRS1_YhbY
MANPEHPH_01137 1.4e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MANPEHPH_01138 2.5e-55
MANPEHPH_01139 5.9e-188 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MANPEHPH_01140 1.7e-252 EGP Major facilitator Superfamily
MANPEHPH_01141 5.1e-33 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MANPEHPH_01143 1.4e-248 rarA L Recombination factor protein RarA
MANPEHPH_01144 0.0 helY L DEAD DEAH box helicase
MANPEHPH_01145 8.1e-199 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MANPEHPH_01147 9.2e-286 ydfD EK Alanine-glyoxylate amino-transferase
MANPEHPH_01148 1.3e-111 argO S LysE type translocator
MANPEHPH_01149 1.4e-289 phoN I PAP2 superfamily
MANPEHPH_01150 1.2e-194 gluD E Binding-protein-dependent transport system inner membrane component
MANPEHPH_01151 1.2e-110 gluC E Binding-protein-dependent transport system inner membrane component
MANPEHPH_01152 5.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
MANPEHPH_01153 3.1e-153 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MANPEHPH_01154 6.1e-102 S Aminoacyl-tRNA editing domain
MANPEHPH_01155 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MANPEHPH_01156 1.7e-260 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MANPEHPH_01157 4.4e-224 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MANPEHPH_01158 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MANPEHPH_01159 9.6e-59 lipA I Hydrolase, alpha beta domain protein
MANPEHPH_01160 3e-132 xylE U Sugar (and other) transporter
MANPEHPH_01161 3e-26 K helix_turn_helix, arabinose operon control protein
MANPEHPH_01162 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MANPEHPH_01163 2.4e-178 uspA T Belongs to the universal stress protein A family
MANPEHPH_01164 1.4e-176 S Protein of unknown function (DUF3027)
MANPEHPH_01165 1.7e-66 cspB K 'Cold-shock' DNA-binding domain
MANPEHPH_01166 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MANPEHPH_01167 2e-132 KT Response regulator receiver domain protein
MANPEHPH_01168 1.3e-100
MANPEHPH_01169 4.5e-35 S Proteins of 100 residues with WXG
MANPEHPH_01170 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MANPEHPH_01171 4.5e-83 S LytR cell envelope-related transcriptional attenuator
MANPEHPH_01172 1.9e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MANPEHPH_01173 1.7e-188 moxR S ATPase family associated with various cellular activities (AAA)
MANPEHPH_01174 3.7e-163 S Protein of unknown function DUF58
MANPEHPH_01175 1.3e-83
MANPEHPH_01176 2.6e-189 S von Willebrand factor (vWF) type A domain
MANPEHPH_01177 1.1e-152 S von Willebrand factor (vWF) type A domain
MANPEHPH_01178 3.1e-56
MANPEHPH_01179 3.1e-255 S PGAP1-like protein
MANPEHPH_01180 1.4e-110 ykoE S ABC-type cobalt transport system, permease component
MANPEHPH_01181 3.3e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MANPEHPH_01182 0.0 S Lysylphosphatidylglycerol synthase TM region
MANPEHPH_01183 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MANPEHPH_01184 3.5e-285 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MANPEHPH_01186 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
MANPEHPH_01187 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MANPEHPH_01188 8.4e-136 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
MANPEHPH_01189 1.7e-162 G Phosphotransferase System
MANPEHPH_01190 2.1e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MANPEHPH_01191 1.1e-78 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MANPEHPH_01192 3.3e-71 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MANPEHPH_01193 3.8e-279 manR K PRD domain
MANPEHPH_01194 1.9e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MANPEHPH_01195 3e-287 arc O AAA ATPase forming ring-shaped complexes
MANPEHPH_01196 2.2e-117 apl 3.1.3.1 S SNARE associated Golgi protein
MANPEHPH_01197 2.1e-118 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MANPEHPH_01198 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MANPEHPH_01199 4.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MANPEHPH_01200 8.7e-187 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MANPEHPH_01201 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MANPEHPH_01202 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MANPEHPH_01203 2.1e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MANPEHPH_01204 1e-149 G Fic/DOC family
MANPEHPH_01205 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MANPEHPH_01206 4.7e-113 3.6.4.12 K Putative DNA-binding domain
MANPEHPH_01207 6.9e-44 K Putative DNA-binding domain
MANPEHPH_01208 9.5e-60 K Putative DNA-binding domain
MANPEHPH_01209 7.5e-11 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
MANPEHPH_01210 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MANPEHPH_01211 7.6e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MANPEHPH_01212 2.7e-67 rbsD 5.4.99.62 G RbsD / FucU transport protein family
MANPEHPH_01213 2.2e-160 rbsB G Periplasmic binding protein domain
MANPEHPH_01214 3.5e-156 rbsC U Branched-chain amino acid transport system / permease component
MANPEHPH_01215 4.7e-277 rbsA 3.6.3.17 G ATPases associated with a variety of cellular activities
MANPEHPH_01216 2.6e-186 rbsR K helix_turn _helix lactose operon repressor
MANPEHPH_01217 4.2e-38 L Transposase
MANPEHPH_01218 2.6e-261 EGP Major Facilitator Superfamily
MANPEHPH_01219 4.1e-164 rbsK 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MANPEHPH_01220 6.4e-229 bdhA C Iron-containing alcohol dehydrogenase
MANPEHPH_01221 7.1e-132 3.1.3.18 S Haloacid dehalogenase-like hydrolase
MANPEHPH_01222 1.1e-189 rihB 3.2.2.1, 3.2.2.8 F Inosine-uridine preferring nucleoside hydrolase
MANPEHPH_01223 2.6e-180 ydjH 2.7.1.15 G pfkB family carbohydrate kinase
MANPEHPH_01224 1.8e-116 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MANPEHPH_01225 1.7e-148 P ATPases associated with a variety of cellular activities
MANPEHPH_01226 5.2e-153 P ATPases associated with a variety of cellular activities
MANPEHPH_01227 6.4e-140 cbiQ P Cobalt transport protein
MANPEHPH_01228 1.2e-99 2.7.7.65 T ECF transporter, substrate-specific component
MANPEHPH_01229 0.0 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MANPEHPH_01230 0.0 V ABC transporter transmembrane region
MANPEHPH_01231 0.0 V ABC transporter, ATP-binding protein
MANPEHPH_01232 7.8e-86 K MarR family
MANPEHPH_01233 4e-176 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
MANPEHPH_01234 3.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MANPEHPH_01235 1.3e-69 S Nucleotidyltransferase substrate binding protein like
MANPEHPH_01236 3.3e-46 S Nucleotidyltransferase domain
MANPEHPH_01237 4.6e-35 mgtC S MgtC family
MANPEHPH_01238 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
MANPEHPH_01239 8.9e-141 K Bacterial regulatory proteins, tetR family
MANPEHPH_01240 1.6e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MANPEHPH_01241 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MANPEHPH_01242 6.5e-136 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MANPEHPH_01243 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MANPEHPH_01244 6.3e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MANPEHPH_01245 3.5e-40 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MANPEHPH_01246 5.1e-91 ywrO 1.6.5.2 S Flavodoxin-like fold
MANPEHPH_01247 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MANPEHPH_01248 8.8e-63 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MANPEHPH_01249 1.4e-77 F Nucleoside 2-deoxyribosyltransferase
MANPEHPH_01251 4.7e-197 S Endonuclease/Exonuclease/phosphatase family
MANPEHPH_01252 3.4e-180 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MANPEHPH_01253 6e-235 aspB E Aminotransferase class-V
MANPEHPH_01254 2.2e-201 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MANPEHPH_01255 1.1e-85 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MANPEHPH_01256 1.2e-100 XK27_03610 K Acetyltransferase (GNAT) domain
MANPEHPH_01257 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MANPEHPH_01258 4e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MANPEHPH_01259 2.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MANPEHPH_01260 6e-151 map 3.4.11.18 E Methionine aminopeptidase
MANPEHPH_01261 1.5e-142 S Short repeat of unknown function (DUF308)
MANPEHPH_01262 0.0 pepO 3.4.24.71 O Peptidase family M13
MANPEHPH_01263 6.6e-114 L Single-strand binding protein family
MANPEHPH_01264 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MANPEHPH_01265 2.6e-155 pflA 1.97.1.4 O Radical SAM superfamily
MANPEHPH_01266 3.7e-268 recD2 3.6.4.12 L PIF1-like helicase
MANPEHPH_01267 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MANPEHPH_01268 4.8e-293 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MANPEHPH_01269 3e-213 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MANPEHPH_01270 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
MANPEHPH_01271 2.5e-124 livF E ATPases associated with a variety of cellular activities
MANPEHPH_01272 1.1e-161 E Branched-chain amino acid ATP-binding cassette transporter
MANPEHPH_01273 1.4e-187 livM U Belongs to the binding-protein-dependent transport system permease family
MANPEHPH_01274 5.4e-111 U Belongs to the binding-protein-dependent transport system permease family
MANPEHPH_01275 1.8e-207 livK E Receptor family ligand binding region
MANPEHPH_01276 1.2e-163 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MANPEHPH_01277 3.7e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MANPEHPH_01278 1.3e-36 rpmE J Binds the 23S rRNA
MANPEHPH_01280 1.1e-99 yebQ EGP Major facilitator Superfamily
MANPEHPH_01281 2.4e-147
MANPEHPH_01282 1.5e-68 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MANPEHPH_01283 8.7e-164 dkgB S Oxidoreductase, aldo keto reductase family protein
MANPEHPH_01284 4.3e-16 EGP Major facilitator superfamily
MANPEHPH_01285 1.2e-86 K Winged helix DNA-binding domain
MANPEHPH_01286 5.3e-178 glkA 2.7.1.2 G ROK family
MANPEHPH_01288 2.1e-308 EGP Major Facilitator Superfamily
MANPEHPH_01289 0.0 yjjK S ATP-binding cassette protein, ChvD family
MANPEHPH_01290 2.5e-169 tesB I Thioesterase-like superfamily
MANPEHPH_01291 3.5e-86 S Protein of unknown function (DUF3180)
MANPEHPH_01292 6.5e-226 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MANPEHPH_01293 1.3e-162 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MANPEHPH_01294 2.8e-117 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MANPEHPH_01295 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MANPEHPH_01296 7.9e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MANPEHPH_01297 2.2e-210 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MANPEHPH_01298 6.7e-252 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MANPEHPH_01299 1.1e-298
MANPEHPH_01300 1e-171 natA V ATPases associated with a variety of cellular activities
MANPEHPH_01301 4.7e-235 epsG M Glycosyl transferase family 21
MANPEHPH_01302 1.9e-281 S AI-2E family transporter
MANPEHPH_01303 2.3e-178 3.4.14.13 M Glycosyltransferase like family 2
MANPEHPH_01304 5.2e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MANPEHPH_01305 1.6e-262 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MANPEHPH_01308 9.9e-161 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MANPEHPH_01310 9.4e-16 L Phage integrase family
MANPEHPH_01311 1.9e-267 lacS G Psort location CytoplasmicMembrane, score 10.00
MANPEHPH_01312 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MANPEHPH_01313 5.3e-184 lacR K Transcriptional regulator, LacI family
MANPEHPH_01314 1.4e-21 L Helix-turn-helix domain
MANPEHPH_01315 4.2e-258 G Bacterial extracellular solute-binding protein
MANPEHPH_01316 1.1e-220 GK ROK family
MANPEHPH_01317 2.5e-15 U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01318 0.0 G Glycosyl hydrolase family 20, domain 2
MANPEHPH_01319 1.2e-08 L HTH-like domain
MANPEHPH_01320 8.1e-220 vex3 V ABC transporter permease
MANPEHPH_01321 7.2e-212 vex1 V Efflux ABC transporter, permease protein
MANPEHPH_01322 4.1e-110 vex2 V ABC transporter, ATP-binding protein
MANPEHPH_01323 4.5e-97 ptpA 3.1.3.48 T low molecular weight
MANPEHPH_01324 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
MANPEHPH_01325 1e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MANPEHPH_01326 3.4e-73 attW O OsmC-like protein
MANPEHPH_01327 1.5e-189 T Universal stress protein family
MANPEHPH_01328 1.5e-103 M NlpC/P60 family
MANPEHPH_01329 2.9e-99 M NlpC/P60 family
MANPEHPH_01330 1.7e-168 usp 3.5.1.28 CBM50 S CHAP domain
MANPEHPH_01331 1.1e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MANPEHPH_01332 1.8e-32
MANPEHPH_01333 6e-174 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MANPEHPH_01334 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
MANPEHPH_01335 1.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MANPEHPH_01336 7.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MANPEHPH_01337 2.3e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MANPEHPH_01339 2.5e-217 araJ EGP Major facilitator Superfamily
MANPEHPH_01340 0.0 S Domain of unknown function (DUF4037)
MANPEHPH_01341 2.9e-116 S Protein of unknown function (DUF4125)
MANPEHPH_01342 0.0 S alpha beta
MANPEHPH_01343 3.7e-67
MANPEHPH_01344 7.9e-286 pspC KT PspC domain
MANPEHPH_01345 4.4e-236 tcsS3 KT PspC domain
MANPEHPH_01346 2.9e-117 degU K helix_turn_helix, Lux Regulon
MANPEHPH_01347 4.1e-168 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MANPEHPH_01348 7.5e-205 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MANPEHPH_01349 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MANPEHPH_01350 2.5e-167 G ABC transporter permease
MANPEHPH_01351 6.9e-173 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_01352 3e-248 G Bacterial extracellular solute-binding protein
MANPEHPH_01354 1.1e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MANPEHPH_01355 4.4e-182 I Diacylglycerol kinase catalytic domain
MANPEHPH_01356 1e-162 arbG K CAT RNA binding domain
MANPEHPH_01357 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
MANPEHPH_01358 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MANPEHPH_01359 3.4e-197 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MANPEHPH_01360 3.6e-73 K Transcriptional regulator
MANPEHPH_01361 1.4e-278 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MANPEHPH_01362 3.3e-171 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MANPEHPH_01363 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MANPEHPH_01365 1.6e-98
MANPEHPH_01366 1.3e-258 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MANPEHPH_01367 9e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MANPEHPH_01368 6.6e-218 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MANPEHPH_01369 4.8e-82 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MANPEHPH_01370 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MANPEHPH_01371 7.7e-186 nusA K Participates in both transcription termination and antitermination
MANPEHPH_01372 3.4e-124
MANPEHPH_01373 8.3e-100 K helix_turn _helix lactose operon repressor
MANPEHPH_01375 3.9e-150 E Transglutaminase/protease-like homologues
MANPEHPH_01376 0.0 gcs2 S A circularly permuted ATPgrasp
MANPEHPH_01377 8.7e-170 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MANPEHPH_01378 1.5e-62 rplQ J Ribosomal protein L17
MANPEHPH_01379 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MANPEHPH_01380 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MANPEHPH_01381 9.5e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MANPEHPH_01382 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MANPEHPH_01383 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MANPEHPH_01384 2.2e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MANPEHPH_01385 6.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MANPEHPH_01386 8.1e-76 rplO J binds to the 23S rRNA
MANPEHPH_01387 7e-26 rpmD J Ribosomal protein L30p/L7e
MANPEHPH_01388 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MANPEHPH_01389 2.7e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MANPEHPH_01390 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MANPEHPH_01391 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MANPEHPH_01392 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MANPEHPH_01393 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MANPEHPH_01394 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MANPEHPH_01395 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MANPEHPH_01396 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MANPEHPH_01397 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
MANPEHPH_01398 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MANPEHPH_01399 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MANPEHPH_01400 5.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MANPEHPH_01401 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MANPEHPH_01402 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MANPEHPH_01403 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MANPEHPH_01404 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
MANPEHPH_01405 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MANPEHPH_01406 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
MANPEHPH_01407 6.1e-134 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MANPEHPH_01408 6.6e-146 ywiC S YwiC-like protein
MANPEHPH_01409 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MANPEHPH_01410 3.1e-170 rhaR_1 K helix_turn_helix, arabinose operon control protein
MANPEHPH_01411 1.5e-194 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
MANPEHPH_01412 1.2e-196 EGP Major facilitator Superfamily
MANPEHPH_01413 2.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MANPEHPH_01414 6e-75 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MANPEHPH_01415 8.3e-233 EGP Major facilitator Superfamily
MANPEHPH_01416 5.1e-179 tdh 1.1.1.14 C Zinc-binding dehydrogenase
MANPEHPH_01417 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MANPEHPH_01418 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
MANPEHPH_01419 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MANPEHPH_01420 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MANPEHPH_01421 8.4e-117
MANPEHPH_01422 3.4e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MANPEHPH_01423 2.8e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MANPEHPH_01424 1.8e-117 M Bacterial capsule synthesis protein PGA_cap
MANPEHPH_01425 6.3e-245 bglA 3.2.1.21 G Glycosyl hydrolase family 1
MANPEHPH_01426 6.1e-160 U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01427 4.7e-163 malC U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01428 1.9e-242 malE G Bacterial extracellular solute-binding protein
MANPEHPH_01429 1.4e-217 rbsR K helix_turn _helix lactose operon repressor
MANPEHPH_01430 5.2e-22
MANPEHPH_01432 7.1e-61 S EamA-like transporter family
MANPEHPH_01433 4.6e-22 S EamA-like transporter family
MANPEHPH_01434 1.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MANPEHPH_01435 6.1e-224 dapC E Aminotransferase class I and II
MANPEHPH_01436 2.9e-59 fdxA C 4Fe-4S binding domain
MANPEHPH_01437 1.8e-268 E aromatic amino acid transport protein AroP K03293
MANPEHPH_01438 8.5e-221 murB 1.3.1.98 M Cell wall formation
MANPEHPH_01439 4.1e-25 rpmG J Ribosomal protein L33
MANPEHPH_01443 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MANPEHPH_01444 1.8e-135
MANPEHPH_01445 1e-114 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MANPEHPH_01446 1.1e-55 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MANPEHPH_01447 4.3e-31 fmdB S Putative regulatory protein
MANPEHPH_01448 3.6e-106 flgA NO SAF
MANPEHPH_01449 6.6e-19 L Superfamily I DNA and RNA helicases and helicase subunits
MANPEHPH_01450 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MANPEHPH_01451 1.1e-192 T Forkhead associated domain
MANPEHPH_01452 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MANPEHPH_01453 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MANPEHPH_01454 5.2e-130 3.2.1.8 S alpha beta
MANPEHPH_01455 1.1e-251 pbuO S Permease family
MANPEHPH_01456 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MANPEHPH_01457 1.3e-171 pstA P Phosphate transport system permease
MANPEHPH_01458 5.7e-156 pstC P probably responsible for the translocation of the substrate across the membrane
MANPEHPH_01459 1.3e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MANPEHPH_01460 3.8e-142 KT Transcriptional regulatory protein, C terminal
MANPEHPH_01461 3.6e-209 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MANPEHPH_01462 1e-240 EGP Sugar (and other) transporter
MANPEHPH_01463 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MANPEHPH_01464 1.9e-236 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MANPEHPH_01465 2e-216 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MANPEHPH_01466 5.9e-85 ebgC G YhcH YjgK YiaL family protein
MANPEHPH_01467 0.0 ebgA 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MANPEHPH_01468 5.6e-115 pgmB 5.4.2.6 S phosphonoacetaldehyde hydrolase activity
MANPEHPH_01469 1.2e-155 EG EamA-like transporter family
MANPEHPH_01470 0.0 kojP 2.4.1.230 GH65 G Glycosyl hydrolase family 65 central catalytic domain
MANPEHPH_01471 1.9e-152 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01472 5.3e-170 malC U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01473 1.8e-237 G Bacterial extracellular solute-binding protein
MANPEHPH_01474 4.6e-188 K Periplasmic binding protein domain
MANPEHPH_01475 2.7e-100 U MarC family integral membrane protein
MANPEHPH_01476 1.1e-266 pepC 3.4.22.40 E Peptidase C1-like family
MANPEHPH_01477 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
MANPEHPH_01478 3.6e-45 D nuclear chromosome segregation
MANPEHPH_01479 2.6e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MANPEHPH_01480 8.4e-151 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MANPEHPH_01481 5.2e-198 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MANPEHPH_01482 6.6e-303 yegQ O Peptidase family U32 C-terminal domain
MANPEHPH_01483 1.4e-178 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MANPEHPH_01484 7.7e-103 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MANPEHPH_01485 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MANPEHPH_01486 2.5e-29 rpmB J Ribosomal L28 family
MANPEHPH_01487 3.2e-197 yegV G pfkB family carbohydrate kinase
MANPEHPH_01488 2.5e-239 yxiO S Vacuole effluxer Atg22 like
MANPEHPH_01489 3.7e-82 soxR K helix_turn_helix, mercury resistance
MANPEHPH_01490 6.5e-60 T Toxic component of a toxin-antitoxin (TA) module
MANPEHPH_01491 9e-53 relB L RelB antitoxin
MANPEHPH_01492 6.1e-25 yxiO G Major facilitator Superfamily
MANPEHPH_01493 1.5e-181 K Helix-turn-helix XRE-family like proteins
MANPEHPH_01494 2.1e-22
MANPEHPH_01495 3.5e-103 S Alpha/beta hydrolase family
MANPEHPH_01499 4.7e-16 EGP Major facilitator Superfamily
MANPEHPH_01500 5.1e-13 XK27_04590 S NADPH-dependent FMN reductase
MANPEHPH_01502 4.5e-294 pccB I Carboxyl transferase domain
MANPEHPH_01503 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MANPEHPH_01504 6.3e-92 bioY S BioY family
MANPEHPH_01505 2.3e-159 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MANPEHPH_01506 0.0
MANPEHPH_01507 2.2e-165 QT PucR C-terminal helix-turn-helix domain
MANPEHPH_01508 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MANPEHPH_01509 6.8e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MANPEHPH_01510 9.6e-146 K Psort location Cytoplasmic, score
MANPEHPH_01511 7e-110 nusG K Participates in transcription elongation, termination and antitermination
MANPEHPH_01512 1.8e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MANPEHPH_01514 4.9e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MANPEHPH_01515 4e-213 G polysaccharide deacetylase
MANPEHPH_01516 2.2e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MANPEHPH_01517 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MANPEHPH_01518 5.8e-39 rpmA J Ribosomal L27 protein
MANPEHPH_01519 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MANPEHPH_01520 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MANPEHPH_01521 4.7e-232 dapE 3.5.1.18 E Peptidase dimerisation domain
MANPEHPH_01522 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MANPEHPH_01523 5.7e-166 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MANPEHPH_01524 3.2e-149 S Amidohydrolase
MANPEHPH_01525 5e-200 fucP G Major Facilitator Superfamily
MANPEHPH_01526 2.8e-148 IQ KR domain
MANPEHPH_01527 1.1e-250 4.2.1.68 M Enolase C-terminal domain-like
MANPEHPH_01528 3.5e-191 K Bacterial regulatory proteins, lacI family
MANPEHPH_01529 3.7e-255 V Efflux ABC transporter, permease protein
MANPEHPH_01530 3.3e-138 V ATPases associated with a variety of cellular activities
MANPEHPH_01531 2.1e-28 S Protein of unknown function (DUF1778)
MANPEHPH_01532 2e-91 K Acetyltransferase (GNAT) family
MANPEHPH_01533 1.7e-276 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MANPEHPH_01534 4.6e-184 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MANPEHPH_01535 1.8e-237 hom 1.1.1.3 E Homoserine dehydrogenase
MANPEHPH_01536 5.6e-54 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MANPEHPH_01537 3e-55 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MANPEHPH_01538 1.7e-301 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MANPEHPH_01539 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MANPEHPH_01540 8.1e-131 K Bacterial regulatory proteins, tetR family
MANPEHPH_01541 8e-222 G Transmembrane secretion effector
MANPEHPH_01542 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MANPEHPH_01543 5.3e-256 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MANPEHPH_01544 2.1e-157 ET Bacterial periplasmic substrate-binding proteins
MANPEHPH_01545 1.8e-119 ytmL P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01546 4e-139 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01547 3.5e-105 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
MANPEHPH_01548 7.7e-132 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
MANPEHPH_01549 7.6e-219 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
MANPEHPH_01550 2.8e-21 2.7.13.3 T Histidine kinase
MANPEHPH_01551 2.3e-15 S Bacterial PH domain
MANPEHPH_01552 3.2e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MANPEHPH_01553 1.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MANPEHPH_01554 2.2e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MANPEHPH_01555 4e-264 S Calcineurin-like phosphoesterase
MANPEHPH_01556 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MANPEHPH_01557 1e-233 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MANPEHPH_01558 3.6e-122
MANPEHPH_01559 0.0 G N-terminal domain of (some) glycogen debranching enzymes
MANPEHPH_01560 1.6e-49 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01561 3.9e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MANPEHPH_01562 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MANPEHPH_01563 1.4e-214 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MANPEHPH_01564 6.7e-217 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MANPEHPH_01566 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MANPEHPH_01567 6.2e-163 S Auxin Efflux Carrier
MANPEHPH_01568 3.4e-157 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MANPEHPH_01569 1.5e-119 S Domain of unknown function (DUF4190)
MANPEHPH_01570 1.1e-164
MANPEHPH_01571 3.5e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
MANPEHPH_01572 1.2e-44 5.3.1.27 G sugar phosphate isomerase involved in capsule formation
MANPEHPH_01573 2e-59 G Branched-chain amino acid transport system / permease component
MANPEHPH_01574 2.9e-73 P branched-chain amino acid ABC transporter, permease protein
MANPEHPH_01575 6.3e-120 G ATPases associated with a variety of cellular activities
MANPEHPH_01576 1.2e-79 G ABC-type sugar transport system periplasmic component
MANPEHPH_01577 3e-167 xylB 1.1.1.57, 2.7.1.17 G Belongs to the FGGY kinase family
MANPEHPH_01578 1e-75 xylR GK ROK family
MANPEHPH_01579 3.3e-36
MANPEHPH_01580 3.2e-200 M Glycosyltransferase like family 2
MANPEHPH_01581 3.3e-181 S Predicted membrane protein (DUF2142)
MANPEHPH_01582 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MANPEHPH_01583 0.0 GT2,GT4 M Glycosyl transferase family 2
MANPEHPH_01584 1.1e-164 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MANPEHPH_01585 1.4e-118 rgpC U Transport permease protein
MANPEHPH_01586 2.1e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MANPEHPH_01587 4.3e-288 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MANPEHPH_01588 1.1e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MANPEHPH_01589 0.0
MANPEHPH_01590 1.9e-167 rfbJ M Glycosyl transferase family 2
MANPEHPH_01591 4.8e-22 M nuclease
MANPEHPH_01592 1.1e-66 M L,D-transpeptidase catalytic domain
MANPEHPH_01593 1.6e-133 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MANPEHPH_01594 2.6e-17 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MANPEHPH_01595 1e-225 K Cell envelope-related transcriptional attenuator domain
MANPEHPH_01596 2.4e-262 V ABC transporter permease
MANPEHPH_01597 8.1e-184 V ABC transporter
MANPEHPH_01598 9.9e-143 T HD domain
MANPEHPH_01599 1.4e-159 S Glutamine amidotransferase domain
MANPEHPH_01600 0.0 kup P Transport of potassium into the cell
MANPEHPH_01601 5.3e-186 tatD L TatD related DNase
MANPEHPH_01602 0.0 yknV V ABC transporter
MANPEHPH_01603 0.0 mdlA2 V ABC transporter
MANPEHPH_01604 3.7e-254 S Domain of unknown function (DUF4143)
MANPEHPH_01605 1e-43 G Glycosyl hydrolases family 43
MANPEHPH_01606 1.5e-149 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MANPEHPH_01607 6.2e-84 pepC 3.4.22.40 E Peptidase C1-like family
MANPEHPH_01608 6.7e-47
MANPEHPH_01609 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MANPEHPH_01610 9.4e-121
MANPEHPH_01611 2.9e-182 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MANPEHPH_01613 6.8e-254 G MFS/sugar transport protein
MANPEHPH_01614 5.1e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MANPEHPH_01615 0.0 lmrA2 V ABC transporter transmembrane region
MANPEHPH_01616 0.0 lmrA1 V ABC transporter, ATP-binding protein
MANPEHPH_01617 2.4e-92 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MANPEHPH_01618 3.2e-278 cycA E Amino acid permease
MANPEHPH_01619 0.0 V FtsX-like permease family
MANPEHPH_01620 2e-129 V ABC transporter
MANPEHPH_01621 2.3e-268 aroP E aromatic amino acid transport protein AroP K03293
MANPEHPH_01622 1.7e-105 S Protein of unknown function, DUF624
MANPEHPH_01623 6.8e-153 rafG G ABC transporter permease
MANPEHPH_01624 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_01625 4.1e-184 K Psort location Cytoplasmic, score
MANPEHPH_01626 1.2e-252 amyE G Bacterial extracellular solute-binding protein
MANPEHPH_01627 3.6e-102 G Phosphoglycerate mutase family
MANPEHPH_01628 4.4e-59 S Protein of unknown function (DUF4235)
MANPEHPH_01629 4.2e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MANPEHPH_01630 0.0 pip S YhgE Pip domain protein
MANPEHPH_01631 5.3e-280 pip S YhgE Pip domain protein
MANPEHPH_01632 1.8e-40
MANPEHPH_01633 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_01634 8.1e-98 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
MANPEHPH_01637 8.6e-70 rplI J Binds to the 23S rRNA
MANPEHPH_01638 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MANPEHPH_01639 6.8e-76 ssb1 L Single-stranded DNA-binding protein
MANPEHPH_01640 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MANPEHPH_01641 1.3e-187 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MANPEHPH_01642 2.2e-154 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MANPEHPH_01643 3.3e-269 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
MANPEHPH_01644 0.0 ubiB S ABC1 family
MANPEHPH_01645 5.5e-38 S granule-associated protein
MANPEHPH_01646 2.7e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MANPEHPH_01647 1.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MANPEHPH_01648 3.3e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MANPEHPH_01649 3e-238 dinF V MatE
MANPEHPH_01650 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MANPEHPH_01651 1e-54 glnB K Nitrogen regulatory protein P-II
MANPEHPH_01652 1e-227 amt U Ammonium Transporter Family
MANPEHPH_01653 2.2e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MANPEHPH_01654 1e-151 icaR K Bacterial regulatory proteins, tetR family
MANPEHPH_01655 1.1e-197 XK27_01805 M Glycosyltransferase like family 2
MANPEHPH_01656 1.1e-302 pepD E Peptidase family C69
MANPEHPH_01658 2.8e-292 3.5.2.6 V Beta-lactamase enzyme family
MANPEHPH_01659 2.9e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MANPEHPH_01660 4.1e-192 opcA G Glucose-6-phosphate dehydrogenase subunit
MANPEHPH_01661 2e-136 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MANPEHPH_01662 1.5e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MANPEHPH_01663 9.4e-253 S Putative ABC-transporter type IV
MANPEHPH_01664 0.0 pip S YhgE Pip domain protein
MANPEHPH_01665 1.8e-306 pip S YhgE Pip domain protein
MANPEHPH_01666 9.2e-101 K Psort location Cytoplasmic, score 8.87
MANPEHPH_01667 1.7e-67 S FMN_bind
MANPEHPH_01668 4.5e-146 macB V ABC transporter, ATP-binding protein
MANPEHPH_01669 2.1e-199 Z012_06715 V FtsX-like permease family
MANPEHPH_01670 7e-221 macB_2 V ABC transporter permease
MANPEHPH_01671 1.7e-232 S Predicted membrane protein (DUF2318)
MANPEHPH_01672 1.6e-99 tpd P Fe2+ transport protein
MANPEHPH_01673 0.0 efeU_1 P Iron permease FTR1 family
MANPEHPH_01675 4.1e-282 L Phage integrase, N-terminal SAM-like domain
MANPEHPH_01676 1.8e-27
MANPEHPH_01677 0.0 T AAA domain
MANPEHPH_01678 9.3e-283 S FRG domain
MANPEHPH_01679 6.7e-231 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MANPEHPH_01680 1.7e-173 S Domain of unknown function (DUF4928)
MANPEHPH_01681 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_01682 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_01683 2.4e-54 L PFAM Integrase catalytic
MANPEHPH_01684 0.0 C Domain of unknown function (DUF4365)
MANPEHPH_01685 3e-50 S Bacteriophage abortive infection AbiH
MANPEHPH_01687 2.7e-88 K Helix-turn-helix XRE-family like proteins
MANPEHPH_01689 2.3e-48 S enterobacterial common antigen metabolic process
MANPEHPH_01690 3.5e-99 S enterobacterial common antigen metabolic process
MANPEHPH_01691 1.6e-41 S Protein of unknown function (DUF3800)
MANPEHPH_01692 2.5e-09 L Helix-turn-helix domain
MANPEHPH_01693 2.4e-264 S Psort location CytoplasmicMembrane, score 9.99
MANPEHPH_01694 8.3e-70
MANPEHPH_01695 1.6e-242 wcoI DM Psort location CytoplasmicMembrane, score
MANPEHPH_01696 1.8e-158
MANPEHPH_01697 3.8e-171 S G5
MANPEHPH_01698 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MANPEHPH_01699 1.2e-120 F Domain of unknown function (DUF4916)
MANPEHPH_01700 1.3e-159 mhpC I Alpha/beta hydrolase family
MANPEHPH_01701 8.2e-211 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MANPEHPH_01702 5.9e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MANPEHPH_01703 5.5e-225 S Uncharacterized conserved protein (DUF2183)
MANPEHPH_01704 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MANPEHPH_01705 5.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MANPEHPH_01706 4.9e-218 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MANPEHPH_01707 2.1e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MANPEHPH_01708 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MANPEHPH_01709 8.2e-230 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MANPEHPH_01710 6.1e-229 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MANPEHPH_01711 2.8e-123 glpR K DeoR C terminal sensor domain
MANPEHPH_01712 8.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MANPEHPH_01713 5.3e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MANPEHPH_01714 6.4e-44 gcvR T Belongs to the UPF0237 family
MANPEHPH_01715 3.2e-253 S UPF0210 protein
MANPEHPH_01716 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MANPEHPH_01717 7e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MANPEHPH_01718 2.3e-128
MANPEHPH_01719 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MANPEHPH_01720 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MANPEHPH_01721 0.0 E Transglutaminase-like superfamily
MANPEHPH_01722 2.5e-239 S Protein of unknown function DUF58
MANPEHPH_01723 0.0 S Fibronectin type 3 domain
MANPEHPH_01724 1.6e-221 KLT Protein tyrosine kinase
MANPEHPH_01725 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MANPEHPH_01726 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MANPEHPH_01727 1.7e-235 G Major Facilitator Superfamily
MANPEHPH_01728 3.5e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MANPEHPH_01729 1.7e-162 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MANPEHPH_01730 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MANPEHPH_01731 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MANPEHPH_01732 2.6e-258 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MANPEHPH_01733 7.5e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MANPEHPH_01734 3.6e-266 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
MANPEHPH_01735 1.6e-205 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MANPEHPH_01736 3e-202 ftsE D Cell division ATP-binding protein FtsE
MANPEHPH_01737 2.8e-160 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MANPEHPH_01738 4e-147 usp 3.5.1.28 CBM50 D CHAP domain protein
MANPEHPH_01739 6.3e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MANPEHPH_01740 5.6e-143 pknD ET ABC transporter, substrate-binding protein, family 3
MANPEHPH_01741 1.7e-168 pknD ET ABC transporter, substrate-binding protein, family 3
MANPEHPH_01742 4.7e-153 yecS E Binding-protein-dependent transport system inner membrane component
MANPEHPH_01743 1.4e-150 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
MANPEHPH_01744 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MANPEHPH_01745 3.6e-142 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MANPEHPH_01746 1.5e-186 K Periplasmic binding protein domain
MANPEHPH_01747 1.2e-166 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_01748 8.5e-57 G ABC transporter permease
MANPEHPH_01749 5.7e-21 G ABC transporter permease
MANPEHPH_01750 2.3e-46 S AAA domain
MANPEHPH_01751 1.6e-177 P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01752 2.9e-165 malC P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01753 4.1e-264 G Bacterial extracellular solute-binding protein
MANPEHPH_01754 2.1e-306 Z012_09690 P Domain of unknown function (DUF4976)
MANPEHPH_01755 3.8e-193 K helix_turn _helix lactose operon repressor
MANPEHPH_01756 2.8e-262 aslB C Iron-sulfur cluster-binding domain
MANPEHPH_01757 5.7e-133 S Sulfite exporter TauE/SafE
MANPEHPH_01758 9.3e-11 L Transposase DDE domain
MANPEHPH_01759 8.6e-273 aspA 4.3.1.1 E Fumarase C C-terminus
MANPEHPH_01760 1.7e-137 M Mechanosensitive ion channel
MANPEHPH_01761 1.1e-184 S CAAX protease self-immunity
MANPEHPH_01762 8.2e-238 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MANPEHPH_01763 6.9e-151 U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01764 2.9e-160 U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01765 9.9e-219 P Bacterial extracellular solute-binding protein
MANPEHPH_01766 2.8e-229 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MANPEHPH_01767 2.7e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MANPEHPH_01768 8.8e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
MANPEHPH_01769 8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
MANPEHPH_01772 2.6e-117 cyaA 4.6.1.1 S CYTH
MANPEHPH_01773 4.5e-172 trxA2 O Tetratricopeptide repeat
MANPEHPH_01774 3e-179
MANPEHPH_01775 2.6e-185
MANPEHPH_01776 5.5e-159 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MANPEHPH_01777 1.4e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MANPEHPH_01778 3.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MANPEHPH_01779 6.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MANPEHPH_01780 5.5e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MANPEHPH_01781 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MANPEHPH_01782 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MANPEHPH_01783 2.9e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MANPEHPH_01784 1.7e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MANPEHPH_01785 6.4e-148 atpB C it plays a direct role in the translocation of protons across the membrane
MANPEHPH_01786 1.6e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MANPEHPH_01788 0.0 K RNA polymerase II activating transcription factor binding
MANPEHPH_01789 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MANPEHPH_01790 8.8e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MANPEHPH_01791 2.8e-97 mntP P Probably functions as a manganese efflux pump
MANPEHPH_01792 1.2e-115
MANPEHPH_01793 4e-139 KT Transcriptional regulatory protein, C terminal
MANPEHPH_01794 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MANPEHPH_01795 7.3e-278 E Bacterial extracellular solute-binding proteins, family 5 Middle
MANPEHPH_01796 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MANPEHPH_01797 0.0 S domain protein
MANPEHPH_01798 6.8e-63 tyrA 5.4.99.5 E Chorismate mutase type II
MANPEHPH_01799 1.2e-21 L Helix-turn-helix domain
MANPEHPH_01800 2.1e-130 rafA 3.2.1.22 G alpha-galactosidase
MANPEHPH_01801 1.3e-114 araQ U Binding-protein-dependent transport system inner membrane component
MANPEHPH_01802 9.5e-121 lacF P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01803 2.6e-154 araN G Bacterial extracellular solute-binding protein
MANPEHPH_01804 5.1e-50 K helix_turn_helix, arabinose operon control protein
MANPEHPH_01805 2e-59 L Transposase
MANPEHPH_01806 1.1e-36 L IstB-like ATP binding protein
MANPEHPH_01807 4.3e-203 drrC L ABC transporter
MANPEHPH_01808 2.7e-247 V MatE
MANPEHPH_01810 2.7e-28 S rRNA binding
MANPEHPH_01811 1.1e-163 K Arac family
MANPEHPH_01812 1.7e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MANPEHPH_01813 6.7e-111 papP E Binding-protein-dependent transport system inner membrane component
MANPEHPH_01814 1.2e-118 E Binding-protein-dependent transport system inner membrane component
MANPEHPH_01815 1.2e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
MANPEHPH_01816 9.6e-155 cjaA ET Bacterial periplasmic substrate-binding proteins
MANPEHPH_01817 1.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MANPEHPH_01818 4.5e-293 pip 3.4.11.5 S alpha/beta hydrolase fold
MANPEHPH_01819 0.0 tcsS2 T Histidine kinase
MANPEHPH_01820 4.5e-141 K helix_turn_helix, Lux Regulon
MANPEHPH_01821 0.0 MV MacB-like periplasmic core domain
MANPEHPH_01822 7.8e-166 V ABC transporter, ATP-binding protein
MANPEHPH_01823 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
MANPEHPH_01824 1.8e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MANPEHPH_01825 1.6e-23 L Transposase and inactivated derivatives IS30 family
MANPEHPH_01826 3.7e-75 yraN L Belongs to the UPF0102 family
MANPEHPH_01827 2e-291 comM O Magnesium chelatase, subunit ChlI C-terminal
MANPEHPH_01828 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MANPEHPH_01829 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MANPEHPH_01830 4.2e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MANPEHPH_01831 1.9e-113 safC S O-methyltransferase
MANPEHPH_01832 1.6e-168 fmt2 3.2.2.10 S Belongs to the LOG family
MANPEHPH_01833 8.7e-238 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MANPEHPH_01834 1.3e-242 patB 4.4.1.8 E Aminotransferase, class I II
MANPEHPH_01837 2.1e-252 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MANPEHPH_01838 7.3e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MANPEHPH_01839 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MANPEHPH_01840 2e-59
MANPEHPH_01841 2.2e-244 clcA_2 P Voltage gated chloride channel
MANPEHPH_01842 6.4e-233 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MANPEHPH_01843 1.8e-253 rnd 3.1.13.5 J 3'-5' exonuclease
MANPEHPH_01844 9.8e-120 S Protein of unknown function (DUF3000)
MANPEHPH_01845 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MANPEHPH_01846 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MANPEHPH_01847 5.8e-38
MANPEHPH_01848 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MANPEHPH_01849 3.7e-226 S Peptidase dimerisation domain
MANPEHPH_01850 9.6e-113 metI P Binding-protein-dependent transport system inner membrane component
MANPEHPH_01851 1.3e-218 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MANPEHPH_01852 4.6e-177 metQ P NLPA lipoprotein
MANPEHPH_01853 4e-156 S Sucrose-6F-phosphate phosphohydrolase
MANPEHPH_01856 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
MANPEHPH_01857 6.5e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MANPEHPH_01858 1.5e-261 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MANPEHPH_01859 1.4e-123 insK L Integrase core domain
MANPEHPH_01860 1.9e-66 L Helix-turn-helix domain
MANPEHPH_01861 4.8e-73 L Transposase
MANPEHPH_01862 1.9e-37 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
MANPEHPH_01864 2.7e-293 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MANPEHPH_01865 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MANPEHPH_01866 3.3e-52 S Protein of unknown function (DUF2469)
MANPEHPH_01867 1.1e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
MANPEHPH_01868 9.6e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MANPEHPH_01869 4.3e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MANPEHPH_01870 4.1e-51 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MANPEHPH_01871 4.2e-38 K Psort location Cytoplasmic, score
MANPEHPH_01872 5.6e-55 K Psort location Cytoplasmic, score
MANPEHPH_01873 1.1e-179
MANPEHPH_01874 6.4e-168 V ABC transporter
MANPEHPH_01875 6.9e-170 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MANPEHPH_01876 3.7e-111 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MANPEHPH_01877 1.6e-210 rmuC S RmuC family
MANPEHPH_01878 3.3e-43 csoR S Metal-sensitive transcriptional repressor
MANPEHPH_01879 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
MANPEHPH_01880 1.9e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MANPEHPH_01881 1e-127 xerH L Belongs to the 'phage' integrase family
MANPEHPH_01882 8.6e-60
MANPEHPH_01883 6.2e-43
MANPEHPH_01884 3.2e-204 EGP Major Facilitator Superfamily
MANPEHPH_01885 6.5e-210 2.7.13.3 T Histidine kinase
MANPEHPH_01886 1.3e-111 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MANPEHPH_01887 3.1e-130 V ABC transporter
MANPEHPH_01888 4.2e-116
MANPEHPH_01889 1.5e-55 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
MANPEHPH_01890 4e-108 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MANPEHPH_01891 2.9e-154 G Binding-protein-dependent transport system inner membrane component
MANPEHPH_01892 1.1e-143 malC G Binding-protein-dependent transport system inner membrane component
MANPEHPH_01893 8.9e-245 msmE7 G Bacterial extracellular solute-binding protein
MANPEHPH_01894 1.2e-230 nagC GK ROK family
MANPEHPH_01895 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MANPEHPH_01896 8.3e-78 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MANPEHPH_01897 0.0 yjcE P Sodium/hydrogen exchanger family
MANPEHPH_01898 1.4e-126 S membrane transporter protein
MANPEHPH_01899 2.1e-145 ypfH S Phospholipase/Carboxylesterase
MANPEHPH_01900 1.6e-152
MANPEHPH_01901 2.2e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MANPEHPH_01902 4.3e-35
MANPEHPH_01903 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MANPEHPH_01904 2e-16 K helix_turn _helix lactose operon repressor
MANPEHPH_01905 7.5e-86 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MANPEHPH_01906 1.6e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MANPEHPH_01907 3.5e-206 EGP Major facilitator Superfamily
MANPEHPH_01908 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MANPEHPH_01909 5.9e-168 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MANPEHPH_01910 4.2e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MANPEHPH_01911 1.6e-271 KLT Domain of unknown function (DUF4032)
MANPEHPH_01912 4.4e-155
MANPEHPH_01913 7.6e-18 tnp7109-21 L Integrase core domain
MANPEHPH_01914 5.1e-49 K helix_turn _helix lactose operon repressor
MANPEHPH_01915 1.5e-69 K helix_turn _helix lactose operon repressor
MANPEHPH_01916 5.4e-146 G Periplasmic binding protein domain
MANPEHPH_01917 8.7e-178 3.6.3.17 G ATPases associated with a variety of cellular activities
MANPEHPH_01918 5e-142 U Branched-chain amino acid transport system / permease component
MANPEHPH_01919 1e-185
MANPEHPH_01920 6.3e-106 tnp3514b L Winged helix-turn helix
MANPEHPH_01921 1.8e-307 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MANPEHPH_01922 3.7e-102 I Sterol carrier protein
MANPEHPH_01923 2.3e-39 S Protein of unknown function (DUF3073)
MANPEHPH_01924 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MANPEHPH_01925 5.1e-306 S Amidohydrolase family
MANPEHPH_01926 1.3e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MANPEHPH_01927 2.8e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MANPEHPH_01928 0.0 yjjP S Threonine/Serine exporter, ThrE
MANPEHPH_01929 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MANPEHPH_01931 2.9e-36 ybfG M Domain of unknown function (DUF1906)
MANPEHPH_01932 1.3e-154 P Belongs to the ABC transporter superfamily
MANPEHPH_01933 2.5e-89 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MANPEHPH_01934 1.9e-122 appB P PFAM binding-protein-dependent transport systems inner membrane component
MANPEHPH_01935 2.6e-191 oppA5 E family 5
MANPEHPH_01936 3.8e-24 trxB1 1.8.1.9 C Thioredoxin domain
MANPEHPH_01937 1.5e-308 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MANPEHPH_01938 1.1e-236 S AAA domain
MANPEHPH_01939 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MANPEHPH_01940 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MANPEHPH_01941 7.6e-110
MANPEHPH_01942 3.2e-86
MANPEHPH_01944 2.4e-276 M LPXTG cell wall anchor motif
MANPEHPH_01945 0.0 Q von Willebrand factor (vWF) type A domain
MANPEHPH_01946 1e-80
MANPEHPH_01947 1.6e-22
MANPEHPH_01949 2.3e-114 P Sodium/hydrogen exchanger family
MANPEHPH_01950 2e-80 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MANPEHPH_01951 1.2e-85 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MANPEHPH_01952 1.9e-258 MA20_36090 S Psort location Cytoplasmic, score 8.87
MANPEHPH_01953 1.3e-106 K Bacterial regulatory proteins, tetR family
MANPEHPH_01954 3e-41 L Transposase, Mutator family
MANPEHPH_01955 1.1e-236 S AAA domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)