ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKKPOGGN_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKPOGGN_00002 8e-70 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00003 1.1e-83 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00004 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00005 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00006 8.4e-44 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00007 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00008 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00013 7.8e-08
HKKPOGGN_00021 1.6e-08
HKKPOGGN_00025 4.4e-286 C Na+/H+ antiporter family
HKKPOGGN_00026 6.6e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HKKPOGGN_00027 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKKPOGGN_00028 3.1e-264 ygaK C Berberine and berberine like
HKKPOGGN_00030 9.8e-231 oppA5 E PFAM extracellular solute-binding protein family 5
HKKPOGGN_00031 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
HKKPOGGN_00032 1.2e-126 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00033 3.1e-136 oppD3 P Belongs to the ABC transporter superfamily
HKKPOGGN_00034 2.8e-134 oppF3 E Belongs to the ABC transporter superfamily
HKKPOGGN_00035 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKPOGGN_00036 2.9e-184 S Amidohydrolase
HKKPOGGN_00037 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HKKPOGGN_00038 2.9e-179 ssuA M Sulfonate ABC transporter
HKKPOGGN_00039 3.4e-144 ssuC P ABC transporter (permease)
HKKPOGGN_00040 1.1e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HKKPOGGN_00041 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKKPOGGN_00042 1.5e-80 ygaO
HKKPOGGN_00043 4.8e-23 K Transcriptional regulator
HKKPOGGN_00045 1.3e-113 yhzB S B3/4 domain
HKKPOGGN_00046 1.9e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKKPOGGN_00047 5e-176 yhbB S Putative amidase domain
HKKPOGGN_00048 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKKPOGGN_00049 3.5e-109 yhbD K Protein of unknown function (DUF4004)
HKKPOGGN_00050 3.3e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKKPOGGN_00051 1.2e-62 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKKPOGGN_00053 0.0 prkA T Ser protein kinase
HKKPOGGN_00054 1.4e-215 yhbH S Belongs to the UPF0229 family
HKKPOGGN_00055 4.6e-74 yhbI K DNA-binding transcription factor activity
HKKPOGGN_00056 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HKKPOGGN_00057 1.1e-284 yhcA EGP Major facilitator Superfamily
HKKPOGGN_00058 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HKKPOGGN_00059 3.8e-55 yhcC
HKKPOGGN_00060 8.1e-52
HKKPOGGN_00061 4.3e-62 yhcF K Transcriptional regulator
HKKPOGGN_00062 1.7e-123 yhcG V ABC transporter, ATP-binding protein
HKKPOGGN_00063 1.5e-166 yhcH V ABC transporter, ATP-binding protein
HKKPOGGN_00064 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKKPOGGN_00065 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HKKPOGGN_00066 1.2e-146 metQ M Belongs to the nlpA lipoprotein family
HKKPOGGN_00067 1.8e-190 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HKKPOGGN_00068 3.5e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKPOGGN_00069 2.7e-55 yhcM
HKKPOGGN_00070 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKPOGGN_00071 2.1e-160 yhcP
HKKPOGGN_00072 7.6e-115 yhcQ M Spore coat protein
HKKPOGGN_00073 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKKPOGGN_00074 6.9e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HKKPOGGN_00075 6.2e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKPOGGN_00076 1.1e-68 yhcU S Family of unknown function (DUF5365)
HKKPOGGN_00077 7.6e-68 yhcV S COG0517 FOG CBS domain
HKKPOGGN_00078 4.9e-125 yhcW 5.4.2.6 S hydrolase
HKKPOGGN_00079 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKKPOGGN_00080 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKPOGGN_00081 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKKPOGGN_00082 1.3e-148 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HKKPOGGN_00083 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKKPOGGN_00084 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HKKPOGGN_00085 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HKKPOGGN_00086 8.5e-207 yhcY 2.7.13.3 T Histidine kinase
HKKPOGGN_00087 3.8e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_00088 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
HKKPOGGN_00089 2.5e-39 yhdB S YhdB-like protein
HKKPOGGN_00090 5.3e-53 yhdC S Protein of unknown function (DUF3889)
HKKPOGGN_00091 6.8e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKPOGGN_00092 5.6e-74 nsrR K Transcriptional regulator
HKKPOGGN_00093 2.9e-255 ygxB M Conserved TM helix
HKKPOGGN_00094 1.2e-271 ycgB S Stage V sporulation protein R
HKKPOGGN_00095 8.9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKKPOGGN_00096 1.4e-126 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKPOGGN_00097 6.4e-162 citR K Transcriptional regulator
HKKPOGGN_00098 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HKKPOGGN_00099 1.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_00100 2.6e-250 yhdG E amino acid
HKKPOGGN_00101 1.3e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKKPOGGN_00102 8.1e-45 yhdK S Sigma-M inhibitor protein
HKKPOGGN_00103 6.6e-201 yhdL S Sigma factor regulator N-terminal
HKKPOGGN_00104 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_00105 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKKPOGGN_00106 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKPOGGN_00107 4.3e-71 cueR K transcriptional
HKKPOGGN_00108 6.1e-224 yhdR 2.6.1.1 E Aminotransferase
HKKPOGGN_00109 2.1e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKKPOGGN_00110 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HKKPOGGN_00111 3.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKKPOGGN_00112 3.9e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKKPOGGN_00113 3.4e-129 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKPOGGN_00115 4.6e-205 yhdY M Mechanosensitive ion channel
HKKPOGGN_00116 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HKKPOGGN_00117 2.7e-157 yheN G deacetylase
HKKPOGGN_00118 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HKKPOGGN_00119 3e-87 pksA K Transcriptional regulator
HKKPOGGN_00120 3.1e-93 ymcC S Membrane
HKKPOGGN_00121 6.2e-85 T universal stress protein
HKKPOGGN_00123 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKPOGGN_00124 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKPOGGN_00125 4.5e-109 yheG GM NAD(P)H-binding
HKKPOGGN_00127 5.8e-29 sspB S spore protein
HKKPOGGN_00128 1.7e-36 yheE S Family of unknown function (DUF5342)
HKKPOGGN_00129 7.9e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HKKPOGGN_00130 4e-214 yheC HJ YheC/D like ATP-grasp
HKKPOGGN_00131 4.2e-206 yheB S Belongs to the UPF0754 family
HKKPOGGN_00132 4.4e-53 yheA S Belongs to the UPF0342 family
HKKPOGGN_00133 2.7e-197 yhaZ L DNA alkylation repair enzyme
HKKPOGGN_00134 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
HKKPOGGN_00135 2.1e-293 hemZ H coproporphyrinogen III oxidase
HKKPOGGN_00136 5.2e-251 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HKKPOGGN_00137 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HKKPOGGN_00138 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKKPOGGN_00140 6.9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
HKKPOGGN_00141 7.3e-15 S YhzD-like protein
HKKPOGGN_00142 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HKKPOGGN_00143 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HKKPOGGN_00144 2.9e-237 yhaO L DNA repair exonuclease
HKKPOGGN_00145 0.0 yhaN L AAA domain
HKKPOGGN_00146 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HKKPOGGN_00147 3.1e-31 yhaL S Sporulation protein YhaL
HKKPOGGN_00148 1.8e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKKPOGGN_00149 7e-95 yhaK S Putative zincin peptidase
HKKPOGGN_00150 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HKKPOGGN_00151 3.3e-112 hpr K Negative regulator of protease production and sporulation
HKKPOGGN_00152 6.2e-39 yhaH S YtxH-like protein
HKKPOGGN_00153 2e-17
HKKPOGGN_00154 1.1e-76 trpP S Tryptophan transporter TrpP
HKKPOGGN_00155 3.5e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKKPOGGN_00156 1.5e-79 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKKPOGGN_00157 1.1e-135 ecsA V transporter (ATP-binding protein)
HKKPOGGN_00158 1.5e-220 ecsB U ABC transporter
HKKPOGGN_00159 6.2e-123 ecsC S EcsC protein family
HKKPOGGN_00160 2.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKKPOGGN_00161 1.8e-243 yhfA C membrane
HKKPOGGN_00162 7.8e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKKPOGGN_00163 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKKPOGGN_00164 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HKKPOGGN_00165 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKKPOGGN_00166 1.6e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HKKPOGGN_00167 1.2e-100 yhgD K Transcriptional regulator
HKKPOGGN_00168 3.3e-274 yhgE S YhgE Pip N-terminal domain protein
HKKPOGGN_00169 1.6e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKKPOGGN_00171 1.9e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HKKPOGGN_00172 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKPOGGN_00173 5.8e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HKKPOGGN_00174 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HKKPOGGN_00175 1.1e-110 yhfK GM NmrA-like family
HKKPOGGN_00176 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKKPOGGN_00177 1.3e-64 yhfM
HKKPOGGN_00178 2.8e-235 yhfN 3.4.24.84 O Peptidase M48
HKKPOGGN_00179 3.4e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HKKPOGGN_00180 1e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HKKPOGGN_00181 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKKPOGGN_00182 1.3e-199 vraB 2.3.1.9 I Belongs to the thiolase family
HKKPOGGN_00183 2.8e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKKPOGGN_00184 2.1e-89 bioY S BioY family
HKKPOGGN_00185 5.7e-199 hemAT NT chemotaxis protein
HKKPOGGN_00186 3.2e-294 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HKKPOGGN_00187 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_00188 1.8e-31 yhzC S IDEAL
HKKPOGGN_00189 1.9e-109 comK K Competence transcription factor
HKKPOGGN_00190 3.9e-68 frataxin S Domain of unknown function (DU1801)
HKKPOGGN_00191 3.4e-64 frataxin S Domain of unknown function (DU1801)
HKKPOGGN_00192 1.4e-53 mepB S MepB protein
HKKPOGGN_00193 5.1e-125 yrpD S Domain of unknown function, YrpD
HKKPOGGN_00194 1.6e-42 yhjA S Excalibur calcium-binding domain
HKKPOGGN_00195 3.3e-47 S Belongs to the UPF0145 family
HKKPOGGN_00196 3.2e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKPOGGN_00197 1.4e-27 yhjC S Protein of unknown function (DUF3311)
HKKPOGGN_00198 2.9e-60 yhjD
HKKPOGGN_00199 4.5e-109 yhjE S SNARE associated Golgi protein
HKKPOGGN_00200 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HKKPOGGN_00201 1.2e-274 yhjG CH FAD binding domain
HKKPOGGN_00202 3.2e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_00203 2.8e-181 abrB S membrane
HKKPOGGN_00204 9.6e-209 blt EGP Major facilitator Superfamily
HKKPOGGN_00205 7.1e-107 K QacR-like protein, C-terminal region
HKKPOGGN_00206 9.7e-94 yhjR S Rubrerythrin
HKKPOGGN_00207 1.5e-124 ydfS S Protein of unknown function (DUF421)
HKKPOGGN_00208 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HKKPOGGN_00209 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKKPOGGN_00210 1.5e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKKPOGGN_00211 0.0 sbcC L COG0419 ATPase involved in DNA repair
HKKPOGGN_00212 2.9e-50 yisB V COG1403 Restriction endonuclease
HKKPOGGN_00213 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HKKPOGGN_00214 1.9e-65 gerPE S Spore germination protein GerPE
HKKPOGGN_00215 3.1e-23 gerPD S Spore germination protein
HKKPOGGN_00216 1.4e-62 gerPC S Spore germination protein
HKKPOGGN_00217 6.2e-35 gerPB S cell differentiation
HKKPOGGN_00218 8.4e-34 gerPA S Spore germination protein
HKKPOGGN_00219 5e-07 yisI S Spo0E like sporulation regulatory protein
HKKPOGGN_00220 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HKKPOGGN_00221 1.1e-59 yisL S UPF0344 protein
HKKPOGGN_00222 6.9e-98 yisN S Protein of unknown function (DUF2777)
HKKPOGGN_00223 0.0 asnO 6.3.5.4 E Asparagine synthase
HKKPOGGN_00224 2.6e-132 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HKKPOGGN_00225 1.5e-245 yisQ V Mate efflux family protein
HKKPOGGN_00226 1.5e-158 yisR K Transcriptional regulator
HKKPOGGN_00227 8.5e-87 yisT S DinB family
HKKPOGGN_00228 3.7e-71 mcbG S Pentapeptide repeats (9 copies)
HKKPOGGN_00229 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
HKKPOGGN_00230 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKKPOGGN_00231 6.6e-55 yajQ S Belongs to the UPF0234 family
HKKPOGGN_00232 1.8e-161 cvfB S protein conserved in bacteria
HKKPOGGN_00233 1.5e-172 yufN S ABC transporter substrate-binding protein PnrA-like
HKKPOGGN_00234 2.4e-210 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HKKPOGGN_00235 2e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HKKPOGGN_00237 4.9e-159 yitS S protein conserved in bacteria
HKKPOGGN_00238 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_00239 5.5e-80 ipi S Intracellular proteinase inhibitor
HKKPOGGN_00240 4.4e-26 S Protein of unknown function (DUF3813)
HKKPOGGN_00241 3.5e-07
HKKPOGGN_00242 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKKPOGGN_00243 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HKKPOGGN_00244 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HKKPOGGN_00245 1.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HKKPOGGN_00246 4e-270 yitY C D-arabinono-1,4-lactone oxidase
HKKPOGGN_00247 1.3e-88 norB G Major Facilitator Superfamily
HKKPOGGN_00248 6.6e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKKPOGGN_00249 3.9e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKKPOGGN_00250 1e-134 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HKKPOGGN_00251 6.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HKKPOGGN_00252 2.4e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKKPOGGN_00253 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HKKPOGGN_00254 3.9e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKKPOGGN_00255 1.2e-27 yjzC S YjzC-like protein
HKKPOGGN_00256 3.3e-23 yjzD S Protein of unknown function (DUF2929)
HKKPOGGN_00257 9.3e-138 yjaU I carboxylic ester hydrolase activity
HKKPOGGN_00258 1e-104 yjaV
HKKPOGGN_00259 1.9e-166 med S Transcriptional activator protein med
HKKPOGGN_00260 1.1e-26 comZ S ComZ
HKKPOGGN_00261 1.7e-31 yjzB
HKKPOGGN_00262 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKKPOGGN_00263 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKKPOGGN_00264 1.6e-148 yjaZ O Zn-dependent protease
HKKPOGGN_00265 2.2e-182 appD P Belongs to the ABC transporter superfamily
HKKPOGGN_00266 2.2e-187 appF E Belongs to the ABC transporter superfamily
HKKPOGGN_00267 5.2e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HKKPOGGN_00268 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00269 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00270 5.5e-146 yjbA S Belongs to the UPF0736 family
HKKPOGGN_00271 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HKKPOGGN_00272 0.0 oppA E ABC transporter substrate-binding protein
HKKPOGGN_00273 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00274 7.9e-163 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00275 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HKKPOGGN_00276 2.1e-171 oppF E Belongs to the ABC transporter superfamily
HKKPOGGN_00277 3.7e-229 S Putative glycosyl hydrolase domain
HKKPOGGN_00278 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKPOGGN_00279 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKKPOGGN_00280 1.4e-108 yjbE P Integral membrane protein TerC family
HKKPOGGN_00281 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKKPOGGN_00282 6.2e-221 yjbF S Competence protein
HKKPOGGN_00283 0.0 pepF E oligoendopeptidase F
HKKPOGGN_00284 5.8e-19
HKKPOGGN_00285 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKKPOGGN_00286 1.8e-71 yjbI S Bacterial-like globin
HKKPOGGN_00287 1.3e-117 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKKPOGGN_00288 2.1e-97 yjbK S protein conserved in bacteria
HKKPOGGN_00289 6e-61 yjbL S Belongs to the UPF0738 family
HKKPOGGN_00290 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
HKKPOGGN_00291 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKKPOGGN_00292 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKPOGGN_00293 4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HKKPOGGN_00294 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKKPOGGN_00295 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKKPOGGN_00296 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HKKPOGGN_00297 5.6e-211 thiO 1.4.3.19 E Glycine oxidase
HKKPOGGN_00298 8.8e-30 thiS H Thiamine biosynthesis
HKKPOGGN_00299 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKKPOGGN_00300 2.1e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKKPOGGN_00301 8.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKKPOGGN_00302 3.4e-138 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKKPOGGN_00303 4.6e-82 yjbX S Spore coat protein
HKKPOGGN_00304 6.9e-80 cotZ S Spore coat protein
HKKPOGGN_00305 1.6e-90 cotY S Spore coat protein Z
HKKPOGGN_00306 4.4e-75 cotX S Spore Coat Protein X and V domain
HKKPOGGN_00307 1.1e-23 cotW
HKKPOGGN_00308 3.6e-56 cotV S Spore Coat Protein X and V domain
HKKPOGGN_00309 7.3e-56 yjcA S Protein of unknown function (DUF1360)
HKKPOGGN_00313 3.8e-38 spoVIF S Stage VI sporulation protein F
HKKPOGGN_00314 0.0 yjcD 3.6.4.12 L DNA helicase
HKKPOGGN_00315 3.5e-36
HKKPOGGN_00316 1.3e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HKKPOGGN_00317 3.4e-124 S ABC-2 type transporter
HKKPOGGN_00318 2.4e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HKKPOGGN_00319 9.4e-36 K SpoVT / AbrB like domain
HKKPOGGN_00320 2.1e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKPOGGN_00321 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HKKPOGGN_00322 1.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
HKKPOGGN_00323 3.5e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKPOGGN_00324 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKPOGGN_00327 1.8e-56
HKKPOGGN_00328 0.0 yobL S Bacterial EndoU nuclease
HKKPOGGN_00331 2e-59 E Glyoxalase-like domain
HKKPOGGN_00332 8.8e-146 bla 3.5.2.6 V beta-lactamase
HKKPOGGN_00333 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
HKKPOGGN_00334 1.2e-250 yfjF EGP Belongs to the major facilitator superfamily
HKKPOGGN_00335 1.1e-80 napB K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_00336 4.7e-218 ganA 3.2.1.89 G arabinogalactan
HKKPOGGN_00337 1.6e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKKPOGGN_00338 2.4e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKKPOGGN_00339 4.2e-217 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKKPOGGN_00340 2.1e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKPOGGN_00341 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HKKPOGGN_00342 4.8e-284 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HKKPOGGN_00343 2.2e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
HKKPOGGN_00344 4.1e-124 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HKKPOGGN_00345 1.3e-33
HKKPOGGN_00346 2.2e-51 K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_00347 3.1e-105 yhiD S MgtC SapB transporter
HKKPOGGN_00349 1.7e-21 yjfB S Putative motility protein
HKKPOGGN_00350 1.1e-68 T PhoQ Sensor
HKKPOGGN_00351 3.8e-99 yjgB S Domain of unknown function (DUF4309)
HKKPOGGN_00352 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HKKPOGGN_00353 1.4e-90 yjgD S Protein of unknown function (DUF1641)
HKKPOGGN_00354 1.4e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HKKPOGGN_00355 2.8e-221 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKKPOGGN_00356 6.8e-29
HKKPOGGN_00357 4.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKKPOGGN_00358 6.4e-124 ybbM S transport system, permease component
HKKPOGGN_00359 3.8e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HKKPOGGN_00360 1.6e-177 yjlA EG Putative multidrug resistance efflux transporter
HKKPOGGN_00361 4.9e-90 yjlB S Cupin domain
HKKPOGGN_00362 7e-66 yjlC S Protein of unknown function (DUF1641)
HKKPOGGN_00363 3.8e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HKKPOGGN_00364 1.1e-277 uxaC 5.3.1.12 G glucuronate isomerase
HKKPOGGN_00365 4.3e-253 yjmB G symporter YjmB
HKKPOGGN_00366 1.3e-182 exuR K transcriptional
HKKPOGGN_00367 1.3e-279 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HKKPOGGN_00368 7.8e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HKKPOGGN_00369 3.9e-131 MA20_18170 S membrane transporter protein
HKKPOGGN_00370 3.1e-78 yjoA S DinB family
HKKPOGGN_00371 1.4e-214 S response regulator aspartate phosphatase
HKKPOGGN_00373 3.8e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKKPOGGN_00374 4.7e-61 yjqA S Bacterial PH domain
HKKPOGGN_00375 2.6e-109 yjqB S phage-related replication protein
HKKPOGGN_00377 7.8e-111 xkdA E IrrE N-terminal-like domain
HKKPOGGN_00378 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HKKPOGGN_00380 2.1e-151 xkdC L Bacterial dnaA protein
HKKPOGGN_00383 2.7e-10 yqaO S Phage-like element PBSX protein XtrA
HKKPOGGN_00384 1.8e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HKKPOGGN_00385 8e-111 xtmA L phage terminase small subunit
HKKPOGGN_00386 2.3e-208 xtmB S phage terminase, large subunit
HKKPOGGN_00387 1.9e-240 yqbA S portal protein
HKKPOGGN_00388 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HKKPOGGN_00389 1e-157 xkdG S Phage capsid family
HKKPOGGN_00390 9.7e-46 yqbG S Protein of unknown function (DUF3199)
HKKPOGGN_00391 4.2e-43 yqbH S Domain of unknown function (DUF3599)
HKKPOGGN_00392 9.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HKKPOGGN_00393 8.3e-57 xkdJ
HKKPOGGN_00394 3.1e-14
HKKPOGGN_00395 1e-225 xkdK S Phage tail sheath C-terminal domain
HKKPOGGN_00396 2e-74 xkdM S Phage tail tube protein
HKKPOGGN_00397 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HKKPOGGN_00398 3.4e-19
HKKPOGGN_00399 9.4e-186 xkdO L Transglycosylase SLT domain
HKKPOGGN_00400 6.6e-111 xkdP S Lysin motif
HKKPOGGN_00401 2.1e-161 xkdQ 3.2.1.96 G NLP P60 protein
HKKPOGGN_00402 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HKKPOGGN_00403 4.2e-58 xkdS S Protein of unknown function (DUF2634)
HKKPOGGN_00404 2.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKKPOGGN_00405 2.5e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKKPOGGN_00406 4.2e-27
HKKPOGGN_00407 2.6e-68
HKKPOGGN_00409 6.5e-30 xkdX
HKKPOGGN_00410 8.7e-139 xepA
HKKPOGGN_00411 8.7e-38 xhlA S Haemolysin XhlA
HKKPOGGN_00412 1.3e-38 xhlB S SPP1 phage holin
HKKPOGGN_00413 6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKPOGGN_00414 8.7e-23 spoIISB S Stage II sporulation protein SB
HKKPOGGN_00415 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HKKPOGGN_00416 7.5e-175 pit P phosphate transporter
HKKPOGGN_00417 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HKKPOGGN_00418 3.8e-243 steT E amino acid
HKKPOGGN_00419 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HKKPOGGN_00420 3e-311 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKKPOGGN_00421 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKPOGGN_00423 1.7e-201 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKPOGGN_00424 4.3e-286 yubD P Major Facilitator Superfamily
HKKPOGGN_00426 1.2e-154 dppA E D-aminopeptidase
HKKPOGGN_00427 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00428 3.2e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKPOGGN_00429 7.7e-191 dppD P Belongs to the ABC transporter superfamily
HKKPOGGN_00430 0.0 dppE E ABC transporter substrate-binding protein
HKKPOGGN_00431 9.2e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HKKPOGGN_00432 1.1e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKKPOGGN_00433 1.3e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKKPOGGN_00434 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
HKKPOGGN_00435 9.6e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HKKPOGGN_00436 6.5e-159 ykgA E Amidinotransferase
HKKPOGGN_00437 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HKKPOGGN_00438 8.8e-101 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKKPOGGN_00439 2.7e-52 ykkC P Multidrug resistance protein
HKKPOGGN_00440 3.4e-49 ykkD P Multidrug resistance protein
HKKPOGGN_00441 3.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HKKPOGGN_00442 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKKPOGGN_00443 1.1e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKKPOGGN_00444 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HKKPOGGN_00445 2.2e-85 ohrR K COG1846 Transcriptional regulators
HKKPOGGN_00446 4.6e-70 ohrB O Organic hydroperoxide resistance protein
HKKPOGGN_00447 2.3e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKKPOGGN_00449 1.7e-215 M Glycosyl transferase family 2
HKKPOGGN_00450 5.5e-128 M PFAM Collagen triple helix repeat (20 copies)
HKKPOGGN_00451 2.7e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HKKPOGGN_00452 1.2e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKKPOGGN_00453 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKKPOGGN_00454 1.7e-176 isp O Belongs to the peptidase S8 family
HKKPOGGN_00455 1.9e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKPOGGN_00456 3e-131 ykoC P Cobalt transport protein
HKKPOGGN_00457 5.2e-306 P ABC transporter, ATP-binding protein
HKKPOGGN_00458 2e-98 ykoE S ABC-type cobalt transport system, permease component
HKKPOGGN_00459 3e-245 ydhD M Glycosyl hydrolase
HKKPOGGN_00461 5e-238 mgtE P Acts as a magnesium transporter
HKKPOGGN_00462 5.4e-53 tnrA K transcriptional
HKKPOGGN_00463 1.9e-16
HKKPOGGN_00464 3.1e-26 ykoL
HKKPOGGN_00465 1.1e-80 ykoM K transcriptional
HKKPOGGN_00466 2.2e-99 ykoP G polysaccharide deacetylase
HKKPOGGN_00467 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HKKPOGGN_00468 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HKKPOGGN_00469 7e-101 ykoX S membrane-associated protein
HKKPOGGN_00470 3.5e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HKKPOGGN_00471 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_00472 8.1e-120 rsgI S Anti-sigma factor N-terminus
HKKPOGGN_00473 7.4e-26 sspD S small acid-soluble spore protein
HKKPOGGN_00474 7.8e-126 ykrK S Domain of unknown function (DUF1836)
HKKPOGGN_00475 1.2e-155 htpX O Belongs to the peptidase M48B family
HKKPOGGN_00476 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
HKKPOGGN_00477 1.3e-114 ydfR S Protein of unknown function (DUF421)
HKKPOGGN_00478 7.9e-24 ykzE
HKKPOGGN_00479 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HKKPOGGN_00480 0.0 kinE 2.7.13.3 T Histidine kinase
HKKPOGGN_00481 1e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKKPOGGN_00483 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HKKPOGGN_00484 1.3e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HKKPOGGN_00485 6.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKKPOGGN_00486 1.9e-228 mtnE 2.6.1.83 E Aminotransferase
HKKPOGGN_00487 2.8e-224 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HKKPOGGN_00488 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HKKPOGGN_00489 4.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HKKPOGGN_00490 9.2e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HKKPOGGN_00491 3.4e-10 S Spo0E like sporulation regulatory protein
HKKPOGGN_00492 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKPOGGN_00493 5.5e-77 ykvE K transcriptional
HKKPOGGN_00494 2.7e-127 motB N Flagellar motor protein
HKKPOGGN_00495 3.3e-136 motA N flagellar motor
HKKPOGGN_00496 0.0 clpE O Belongs to the ClpA ClpB family
HKKPOGGN_00497 5.6e-181 ykvI S membrane
HKKPOGGN_00498 4.6e-189
HKKPOGGN_00499 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKKPOGGN_00500 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
HKKPOGGN_00501 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKKPOGGN_00502 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKKPOGGN_00504 3.4e-58 ykvN K Transcriptional regulator
HKKPOGGN_00505 3.5e-132 IQ Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_00506 1.9e-43 ykvR S Protein of unknown function (DUF3219)
HKKPOGGN_00507 7.8e-25 ykvS S protein conserved in bacteria
HKKPOGGN_00508 3e-27
HKKPOGGN_00509 1.8e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
HKKPOGGN_00510 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_00511 5.9e-88 stoA CO thiol-disulfide
HKKPOGGN_00512 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKKPOGGN_00513 4.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKKPOGGN_00515 2.3e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HKKPOGGN_00516 4.3e-155 glcT K antiterminator
HKKPOGGN_00517 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKPOGGN_00518 2.1e-39 ptsH G phosphocarrier protein HPr
HKKPOGGN_00519 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKKPOGGN_00520 6.1e-38 splA S Transcriptional regulator
HKKPOGGN_00521 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
HKKPOGGN_00522 2e-264 mcpC NT chemotaxis protein
HKKPOGGN_00523 2.8e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HKKPOGGN_00524 3.9e-110 ykwD J protein with SCP PR1 domains
HKKPOGGN_00525 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HKKPOGGN_00526 2.2e-289 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HKKPOGGN_00527 3.9e-215 patA 2.6.1.1 E Aminotransferase
HKKPOGGN_00528 2.3e-09
HKKPOGGN_00529 3.4e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
HKKPOGGN_00530 1.4e-83 ykyB S YkyB-like protein
HKKPOGGN_00531 3e-240 ykuC EGP Major facilitator Superfamily
HKKPOGGN_00532 9.2e-89 ykuD S protein conserved in bacteria
HKKPOGGN_00533 3.7e-154 ykuE S Metallophosphoesterase
HKKPOGGN_00534 8.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_00536 3.3e-233 ykuI T Diguanylate phosphodiesterase
HKKPOGGN_00537 3.9e-37 ykuJ S protein conserved in bacteria
HKKPOGGN_00538 4.9e-93 ykuK S Ribonuclease H-like
HKKPOGGN_00539 2.1e-25 ykzF S Antirepressor AbbA
HKKPOGGN_00540 1e-75 ykuL S CBS domain
HKKPOGGN_00541 4.6e-168 ccpC K Transcriptional regulator
HKKPOGGN_00542 1.5e-88 fld C Flavodoxin
HKKPOGGN_00543 1.2e-171 ykuO
HKKPOGGN_00544 9.3e-80 fld C Flavodoxin
HKKPOGGN_00545 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKKPOGGN_00546 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKKPOGGN_00547 4.8e-38 ykuS S Belongs to the UPF0180 family
HKKPOGGN_00548 4.1e-139 ykuT M Mechanosensitive ion channel
HKKPOGGN_00549 6.1e-79 ykuV CO thiol-disulfide
HKKPOGGN_00550 4.5e-98 rok K Repressor of ComK
HKKPOGGN_00551 1.1e-162 yknT
HKKPOGGN_00552 4.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKKPOGGN_00553 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKKPOGGN_00554 1.3e-243 moeA 2.10.1.1 H molybdopterin
HKKPOGGN_00555 3.4e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HKKPOGGN_00556 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HKKPOGGN_00557 5.7e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HKKPOGGN_00558 3.4e-105 yknW S Yip1 domain
HKKPOGGN_00559 5.2e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKKPOGGN_00560 3e-122 macB V ABC transporter, ATP-binding protein
HKKPOGGN_00561 4.6e-211 yknZ V ABC transporter (permease)
HKKPOGGN_00562 1e-131 fruR K Transcriptional regulator
HKKPOGGN_00563 2e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HKKPOGGN_00564 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HKKPOGGN_00565 2.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKPOGGN_00566 1.2e-37 ykoA
HKKPOGGN_00567 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKPOGGN_00568 9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKKPOGGN_00569 3.8e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKKPOGGN_00570 5.5e-12 S Uncharacterized protein YkpC
HKKPOGGN_00571 6.9e-184 mreB D Rod-share determining protein MreBH
HKKPOGGN_00572 2.1e-45 abrB K of stationary sporulation gene expression
HKKPOGGN_00573 8.2e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKPOGGN_00574 7e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HKKPOGGN_00575 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HKKPOGGN_00576 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKKPOGGN_00577 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKKPOGGN_00578 2.4e-30 ykzG S Belongs to the UPF0356 family
HKKPOGGN_00579 2.6e-146 ykrA S hydrolases of the HAD superfamily
HKKPOGGN_00580 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKKPOGGN_00582 5e-103 recN L Putative cell-wall binding lipoprotein
HKKPOGGN_00583 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_00584 0.0 Q Polyketide synthase of type I
HKKPOGGN_00585 0.0 Q polyketide synthase
HKKPOGGN_00586 0.0 Q Polyketide synthase of type I
HKKPOGGN_00587 0.0 Q Polyketide synthase of type I
HKKPOGGN_00588 0.0 Q Polyketide synthase of type I
HKKPOGGN_00589 0.0 Q Polyketide synthase of type I
HKKPOGGN_00590 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HKKPOGGN_00591 6.7e-209 V Beta-lactamase
HKKPOGGN_00592 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKPOGGN_00593 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKPOGGN_00594 1.3e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKPOGGN_00595 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKPOGGN_00596 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HKKPOGGN_00597 1.4e-139 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HKKPOGGN_00598 1.6e-277 speA 4.1.1.19 E Arginine
HKKPOGGN_00599 5e-41 yktA S Belongs to the UPF0223 family
HKKPOGGN_00600 1.8e-118 yktB S Belongs to the UPF0637 family
HKKPOGGN_00601 9.7e-25 ykzI
HKKPOGGN_00602 6.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
HKKPOGGN_00603 8.9e-83 ykzC S Acetyltransferase (GNAT) family
HKKPOGGN_00604 1.8e-295 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HKKPOGGN_00605 4.8e-194 ylaA
HKKPOGGN_00606 8.9e-46 ylaB
HKKPOGGN_00607 7.2e-90 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_00608 3.7e-13 sigC S Putative zinc-finger
HKKPOGGN_00609 1.4e-38 ylaE
HKKPOGGN_00610 6.7e-24 S Family of unknown function (DUF5325)
HKKPOGGN_00611 0.0 typA T GTP-binding protein TypA
HKKPOGGN_00612 1.3e-48 ylaH S YlaH-like protein
HKKPOGGN_00613 1e-33 ylaI S protein conserved in bacteria
HKKPOGGN_00614 1.7e-103 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKPOGGN_00615 8.3e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HKKPOGGN_00616 1.1e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HKKPOGGN_00617 5e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
HKKPOGGN_00618 8.7e-44 ylaN S Belongs to the UPF0358 family
HKKPOGGN_00619 2.9e-213 ftsW D Belongs to the SEDS family
HKKPOGGN_00620 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKKPOGGN_00621 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HKKPOGGN_00622 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKKPOGGN_00623 3.1e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HKKPOGGN_00624 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKKPOGGN_00625 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HKKPOGGN_00626 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HKKPOGGN_00627 1.8e-164 ctaG S cytochrome c oxidase
HKKPOGGN_00628 8.5e-60 ylbA S YugN-like family
HKKPOGGN_00629 6.3e-73 ylbB T COG0517 FOG CBS domain
HKKPOGGN_00630 5.1e-198 ylbC S protein with SCP PR1 domains
HKKPOGGN_00631 6.5e-56 ylbD S Putative coat protein
HKKPOGGN_00632 8.8e-37 ylbE S YlbE-like protein
HKKPOGGN_00633 1.2e-71 ylbF S Belongs to the UPF0342 family
HKKPOGGN_00634 7.2e-43 ylbG S UPF0298 protein
HKKPOGGN_00636 3.5e-97 rsmD 2.1.1.171 L Methyltransferase
HKKPOGGN_00637 8.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKKPOGGN_00638 2.8e-216 ylbJ S Sporulation integral membrane protein YlbJ
HKKPOGGN_00639 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HKKPOGGN_00640 6.1e-188 ylbL T Belongs to the peptidase S16 family
HKKPOGGN_00641 1e-229 ylbM S Belongs to the UPF0348 family
HKKPOGGN_00642 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
HKKPOGGN_00643 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKKPOGGN_00644 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HKKPOGGN_00645 3.1e-89 ylbP K n-acetyltransferase
HKKPOGGN_00646 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKKPOGGN_00647 3.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HKKPOGGN_00648 8.9e-78 mraZ K Belongs to the MraZ family
HKKPOGGN_00649 4.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKKPOGGN_00650 2.9e-52 ftsL D Essential cell division protein
HKKPOGGN_00651 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKKPOGGN_00652 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HKKPOGGN_00653 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKKPOGGN_00654 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKKPOGGN_00655 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKKPOGGN_00656 2.2e-185 spoVE D Belongs to the SEDS family
HKKPOGGN_00657 5.1e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKKPOGGN_00658 3.7e-168 murB 1.3.1.98 M cell wall formation
HKKPOGGN_00659 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKKPOGGN_00660 3.5e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKKPOGGN_00661 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKKPOGGN_00662 0.0 bpr O COG1404 Subtilisin-like serine proteases
HKKPOGGN_00663 2.2e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HKKPOGGN_00664 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_00665 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_00666 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HKKPOGGN_00667 1.6e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HKKPOGGN_00668 2.2e-38 ylmC S sporulation protein
HKKPOGGN_00669 1.8e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HKKPOGGN_00670 1.4e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKKPOGGN_00671 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKKPOGGN_00672 5.2e-41 yggT S membrane
HKKPOGGN_00673 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HKKPOGGN_00674 8.9e-68 divIVA D Cell division initiation protein
HKKPOGGN_00675 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKKPOGGN_00676 3.8e-63 dksA T COG1734 DnaK suppressor protein
HKKPOGGN_00677 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKKPOGGN_00678 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKPOGGN_00679 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKKPOGGN_00680 1.2e-231 pyrP F Xanthine uracil
HKKPOGGN_00681 3.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKKPOGGN_00682 5.6e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKKPOGGN_00683 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKKPOGGN_00684 0.0 carB 6.3.5.5 F Belongs to the CarB family
HKKPOGGN_00685 3.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKKPOGGN_00686 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKKPOGGN_00687 3.9e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKKPOGGN_00688 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKKPOGGN_00690 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKKPOGGN_00691 5.4e-179 cysP P phosphate transporter
HKKPOGGN_00692 3.8e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKKPOGGN_00693 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HKKPOGGN_00694 5.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKKPOGGN_00695 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HKKPOGGN_00696 6.5e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HKKPOGGN_00697 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HKKPOGGN_00698 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HKKPOGGN_00699 1e-154 yloC S stress-induced protein
HKKPOGGN_00700 1.5e-40 ylzA S Belongs to the UPF0296 family
HKKPOGGN_00701 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKKPOGGN_00702 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKKPOGGN_00703 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKKPOGGN_00704 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKKPOGGN_00705 1.7e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKKPOGGN_00706 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKKPOGGN_00707 8.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKKPOGGN_00708 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKKPOGGN_00709 8.7e-139 stp 3.1.3.16 T phosphatase
HKKPOGGN_00710 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKKPOGGN_00711 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKKPOGGN_00712 4e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKKPOGGN_00713 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKKPOGGN_00714 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKKPOGGN_00715 5.5e-59 asp S protein conserved in bacteria
HKKPOGGN_00716 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HKKPOGGN_00717 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HKKPOGGN_00718 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HKKPOGGN_00719 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKKPOGGN_00720 3.5e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HKKPOGGN_00721 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKKPOGGN_00722 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_00723 3.9e-128 IQ reductase
HKKPOGGN_00724 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKKPOGGN_00725 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKKPOGGN_00726 0.0 smc D Required for chromosome condensation and partitioning
HKKPOGGN_00727 2.4e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKKPOGGN_00728 8.5e-142 S Phosphotransferase enzyme family
HKKPOGGN_00729 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKKPOGGN_00730 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKKPOGGN_00731 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKKPOGGN_00732 1.7e-35 ylqC S Belongs to the UPF0109 family
HKKPOGGN_00733 1.3e-61 ylqD S YlqD protein
HKKPOGGN_00734 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKKPOGGN_00735 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKKPOGGN_00736 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKKPOGGN_00737 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKKPOGGN_00738 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKKPOGGN_00739 6.6e-304 ylqG
HKKPOGGN_00740 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HKKPOGGN_00741 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKKPOGGN_00742 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKKPOGGN_00743 1.5e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HKKPOGGN_00744 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKKPOGGN_00745 2.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKKPOGGN_00746 7.2e-172 xerC L tyrosine recombinase XerC
HKKPOGGN_00747 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKKPOGGN_00748 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKKPOGGN_00749 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKKPOGGN_00750 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HKKPOGGN_00751 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
HKKPOGGN_00752 2.5e-31 fliE N Flagellar hook-basal body
HKKPOGGN_00753 6.7e-258 fliF N The M ring may be actively involved in energy transduction
HKKPOGGN_00754 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKPOGGN_00755 1.5e-90 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HKKPOGGN_00756 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HKKPOGGN_00757 1.3e-70 fliJ N Flagellar biosynthesis chaperone
HKKPOGGN_00758 2.6e-45 ylxF S MgtE intracellular N domain
HKKPOGGN_00759 6.1e-204 fliK N Flagellar hook-length control protein
HKKPOGGN_00760 1.4e-72 flgD N Flagellar basal body rod modification protein
HKKPOGGN_00761 2e-138 flgG N Flagellar basal body rod
HKKPOGGN_00762 1.9e-55 fliL N Controls the rotational direction of flagella during chemotaxis
HKKPOGGN_00763 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKPOGGN_00764 2.8e-186 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKPOGGN_00765 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HKKPOGGN_00766 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
HKKPOGGN_00767 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HKKPOGGN_00768 2e-37 fliQ N Role in flagellar biosynthesis
HKKPOGGN_00769 4.4e-130 fliR N Flagellar biosynthetic protein FliR
HKKPOGGN_00770 9e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKKPOGGN_00771 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKKPOGGN_00772 1.4e-193 flhF N Flagellar biosynthesis regulator FlhF
HKKPOGGN_00773 1.1e-156 flhG D Belongs to the ParA family
HKKPOGGN_00774 2.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HKKPOGGN_00775 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HKKPOGGN_00776 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HKKPOGGN_00777 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HKKPOGGN_00778 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HKKPOGGN_00779 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_00780 6.9e-54 ylxL
HKKPOGGN_00781 1.4e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
HKKPOGGN_00782 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKKPOGGN_00783 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKKPOGGN_00784 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKKPOGGN_00785 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKKPOGGN_00786 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
HKKPOGGN_00787 1.1e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKKPOGGN_00788 1.5e-233 rasP M zinc metalloprotease
HKKPOGGN_00789 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKKPOGGN_00790 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKKPOGGN_00791 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HKKPOGGN_00792 5.4e-206 nusA K Participates in both transcription termination and antitermination
HKKPOGGN_00793 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HKKPOGGN_00794 1.8e-47 ylxQ J ribosomal protein
HKKPOGGN_00795 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKKPOGGN_00796 3.9e-44 ylxP S protein conserved in bacteria
HKKPOGGN_00797 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKKPOGGN_00798 3.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKKPOGGN_00799 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKKPOGGN_00800 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKKPOGGN_00801 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKKPOGGN_00802 3e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HKKPOGGN_00803 2e-233 pepR S Belongs to the peptidase M16 family
HKKPOGGN_00804 2.6e-42 ymxH S YlmC YmxH family
HKKPOGGN_00805 1.8e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HKKPOGGN_00806 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HKKPOGGN_00807 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKKPOGGN_00808 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKKPOGGN_00809 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKKPOGGN_00810 5.2e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKKPOGGN_00811 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HKKPOGGN_00812 6.3e-31 S YlzJ-like protein
HKKPOGGN_00813 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKKPOGGN_00814 1.8e-133 ymfC K Transcriptional regulator
HKKPOGGN_00815 1.1e-229 ymfD EGP Major facilitator Superfamily
HKKPOGGN_00816 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_00817 0.0 ydgH S drug exporters of the RND superfamily
HKKPOGGN_00818 3.6e-238 ymfF S Peptidase M16
HKKPOGGN_00819 7.5e-244 ymfH S zinc protease
HKKPOGGN_00820 4.3e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HKKPOGGN_00821 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HKKPOGGN_00822 1e-142 ymfK S Protein of unknown function (DUF3388)
HKKPOGGN_00823 4.2e-124 ymfM S protein conserved in bacteria
HKKPOGGN_00824 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKKPOGGN_00825 6e-230 cinA 3.5.1.42 S Belongs to the CinA family
HKKPOGGN_00826 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKKPOGGN_00827 1.2e-182 pbpX V Beta-lactamase
HKKPOGGN_00828 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HKKPOGGN_00829 4.9e-153 ymdB S protein conserved in bacteria
HKKPOGGN_00830 1.2e-36 spoVS S Stage V sporulation protein S
HKKPOGGN_00831 3.9e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HKKPOGGN_00832 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKKPOGGN_00833 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKKPOGGN_00834 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HKKPOGGN_00835 1.7e-88 cotE S Spore coat protein
HKKPOGGN_00836 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKKPOGGN_00837 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKKPOGGN_00839 4.8e-128 pksB 3.1.2.6 S Polyketide biosynthesis
HKKPOGGN_00840 1.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_00841 1.9e-183 pksD Q Acyl transferase domain
HKKPOGGN_00842 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_00843 3.8e-35 acpK IQ Phosphopantetheine attachment site
HKKPOGGN_00844 2.4e-242 pksG 2.3.3.10 I synthase
HKKPOGGN_00845 8.5e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
HKKPOGGN_00846 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HKKPOGGN_00847 0.0 rhiB IQ polyketide synthase
HKKPOGGN_00848 0.0 Q Polyketide synthase of type I
HKKPOGGN_00849 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HKKPOGGN_00850 0.0 dhbF IQ polyketide synthase
HKKPOGGN_00851 0.0 pks13 HQ Beta-ketoacyl synthase
HKKPOGGN_00852 6.9e-231 cypA C Cytochrome P450
HKKPOGGN_00853 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
HKKPOGGN_00854 3.6e-118 yoaK S Membrane
HKKPOGGN_00855 1.4e-62 ymzB
HKKPOGGN_00856 5.7e-255 aprX O Belongs to the peptidase S8 family
HKKPOGGN_00858 3.3e-124 ymaC S Replication protein
HKKPOGGN_00859 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
HKKPOGGN_00860 5.2e-54 ebrB P Small Multidrug Resistance protein
HKKPOGGN_00861 3.1e-48 ebrA P Small Multidrug Resistance protein
HKKPOGGN_00863 4.1e-47 ymaF S YmaF family
HKKPOGGN_00864 1.5e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKKPOGGN_00865 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HKKPOGGN_00866 8.5e-44
HKKPOGGN_00867 1.8e-20 ymzA
HKKPOGGN_00868 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HKKPOGGN_00869 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKKPOGGN_00870 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKKPOGGN_00871 3.4e-109 ymaB S MutT family
HKKPOGGN_00872 7.4e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKPOGGN_00873 5.1e-176 spoVK O stage V sporulation protein K
HKKPOGGN_00874 3.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKKPOGGN_00875 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HKKPOGGN_00876 1.6e-67 glnR K transcriptional
HKKPOGGN_00877 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
HKKPOGGN_00879 1.4e-15
HKKPOGGN_00880 1.2e-22 xerH A Belongs to the 'phage' integrase family
HKKPOGGN_00881 2.4e-248 xynT G MFS/sugar transport protein
HKKPOGGN_00882 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKPOGGN_00883 1.2e-216 xylR GK ROK family
HKKPOGGN_00884 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKKPOGGN_00885 9.3e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HKKPOGGN_00886 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HKKPOGGN_00890 5.4e-17
HKKPOGGN_00891 1.8e-90 K WYL domain
HKKPOGGN_00892 2e-67 S DinB family
HKKPOGGN_00893 1.5e-186 adhP 1.1.1.1 C alcohol dehydrogenase
HKKPOGGN_00894 5.4e-17 ccmM S Bacterial transferase hexapeptide (six repeats)
HKKPOGGN_00895 1.6e-26 ccmM S Bacterial transferase hexapeptide (six repeats)
HKKPOGGN_00897 1.5e-16
HKKPOGGN_00899 3e-147 yoaP 3.1.3.18 K YoaP-like
HKKPOGGN_00900 9e-98 J Acetyltransferase (GNAT) domain
HKKPOGGN_00902 1.5e-23
HKKPOGGN_00903 8e-20
HKKPOGGN_00905 6.4e-116 ynaE S Domain of unknown function (DUF3885)
HKKPOGGN_00906 3e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_00907 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HKKPOGGN_00909 4.6e-94 yvgO
HKKPOGGN_00911 0.0 yobO M Pectate lyase superfamily protein
HKKPOGGN_00912 8.3e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HKKPOGGN_00913 7.4e-144 yndL S Replication protein
HKKPOGGN_00914 1.6e-07
HKKPOGGN_00915 3.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HKKPOGGN_00916 2.4e-72 yndM S Protein of unknown function (DUF2512)
HKKPOGGN_00917 1.7e-11 yoaW
HKKPOGGN_00918 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKKPOGGN_00919 1.8e-50 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HKKPOGGN_00920 1.3e-111 yneB L resolvase
HKKPOGGN_00921 9.8e-33 ynzC S UPF0291 protein
HKKPOGGN_00922 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKKPOGGN_00923 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HKKPOGGN_00924 2.3e-28 yneF S UPF0154 protein
HKKPOGGN_00925 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
HKKPOGGN_00926 1.7e-125 ccdA O cytochrome c biogenesis protein
HKKPOGGN_00927 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HKKPOGGN_00928 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HKKPOGGN_00929 9.4e-74 yneK S Protein of unknown function (DUF2621)
HKKPOGGN_00930 9.3e-62 hspX O Spore coat protein
HKKPOGGN_00931 2.3e-19 sspP S Belongs to the SspP family
HKKPOGGN_00932 7.5e-15 sspO S Belongs to the SspO family
HKKPOGGN_00933 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKKPOGGN_00934 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKKPOGGN_00936 2.7e-33 tlp S Belongs to the Tlp family
HKKPOGGN_00937 8.3e-75 yneP S Thioesterase-like superfamily
HKKPOGGN_00938 3.7e-53 yneQ
HKKPOGGN_00939 1.7e-50 yneR S Belongs to the HesB IscA family
HKKPOGGN_00940 1.9e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKKPOGGN_00941 1.5e-68 yccU S CoA-binding protein
HKKPOGGN_00942 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKKPOGGN_00943 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKKPOGGN_00944 1.6e-13
HKKPOGGN_00945 5.1e-41 ynfC
HKKPOGGN_00946 1.3e-249 agcS E Sodium alanine symporter
HKKPOGGN_00947 6.1e-182 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HKKPOGGN_00948 1.2e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HKKPOGGN_00949 5.8e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HKKPOGGN_00950 3.1e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKKPOGGN_00951 1.6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_00952 2.7e-180 kdgR_1 K transcriptional
HKKPOGGN_00953 1.2e-222 exuT G Sugar (and other) transporter
HKKPOGGN_00954 8.9e-104 yndG S DoxX-like family
HKKPOGGN_00955 1.1e-78 yndH S Domain of unknown function (DUF4166)
HKKPOGGN_00956 5.8e-189 yndJ S YndJ-like protein
HKKPOGGN_00957 9.4e-49 yndJ S YndJ-like protein
HKKPOGGN_00958 9.6e-11 yxlH EGP Major facilitator Superfamily
HKKPOGGN_00960 4.2e-214 S Platelet-activating factor acetylhydrolase, isoform II
HKKPOGGN_00962 7.5e-233 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HKKPOGGN_00963 4e-50 S Domain of unknown function (DUF4870)
HKKPOGGN_00964 6.5e-233 T PhoQ Sensor
HKKPOGGN_00965 9.9e-129 T Transcriptional regulatory protein, C terminal
HKKPOGGN_00966 2.2e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HKKPOGGN_00967 8.9e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HKKPOGGN_00968 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00969 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00970 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00971 1.3e-226 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_00972 4e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKKPOGGN_00973 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKKPOGGN_00974 3.8e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKKPOGGN_00975 1.3e-252 yxjC EG COG2610 H gluconate symporter and related permeases
HKKPOGGN_00976 2e-222 bioI 1.14.14.46 C Cytochrome P450
HKKPOGGN_00977 1.4e-192 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HKKPOGGN_00978 3.2e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HKKPOGGN_00979 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKKPOGGN_00980 2.1e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HKKPOGGN_00981 5e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HKKPOGGN_00982 5e-72 yngA S membrane
HKKPOGGN_00983 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKPOGGN_00984 3.2e-104 yngC S SNARE associated Golgi protein
HKKPOGGN_00985 1.2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKKPOGGN_00986 1.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKKPOGGN_00987 7.3e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HKKPOGGN_00988 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HKKPOGGN_00989 2.3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HKKPOGGN_00990 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKKPOGGN_00991 6.3e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HKKPOGGN_00992 5.9e-304 yngK T Glycosyl hydrolase-like 10
HKKPOGGN_00993 1.2e-64 yngL S Protein of unknown function (DUF1360)
HKKPOGGN_00994 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HKKPOGGN_00995 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_00996 1.5e-183 yaaC S YaaC-like Protein
HKKPOGGN_00997 2.3e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKKPOGGN_00998 1.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKKPOGGN_00999 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKKPOGGN_01000 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKKPOGGN_01001 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKKPOGGN_01002 5.7e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKKPOGGN_01003 1.3e-09
HKKPOGGN_01004 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HKKPOGGN_01005 2.1e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HKKPOGGN_01006 8.9e-213 yaaH M Glycoside Hydrolase Family
HKKPOGGN_01007 8.3e-99 yaaI Q COG1335 Amidases related to nicotinamidase
HKKPOGGN_01008 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKKPOGGN_01009 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKKPOGGN_01010 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKKPOGGN_01011 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKKPOGGN_01012 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HKKPOGGN_01013 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HKKPOGGN_01014 4.3e-86 pksJ Q Polyketide synthase of type I
HKKPOGGN_01015 5.5e-130 IQ reductase
HKKPOGGN_01016 1e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKKPOGGN_01019 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKPOGGN_01020 3.8e-93 nusG K Participates in transcription elongation, termination and antitermination
HKKPOGGN_01021 3.4e-163 K LysR substrate binding domain
HKKPOGGN_01022 2.1e-49 S GlpM protein
HKKPOGGN_01023 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HKKPOGGN_01024 3.9e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKKPOGGN_01025 7.2e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKKPOGGN_01026 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKKPOGGN_01027 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKKPOGGN_01028 2.8e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKKPOGGN_01029 1.1e-25 yqzJ
HKKPOGGN_01030 9.5e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKKPOGGN_01031 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HKKPOGGN_01032 6.5e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKKPOGGN_01033 1.2e-73 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HKKPOGGN_01035 1.4e-95 yqjB S protein conserved in bacteria
HKKPOGGN_01036 5.3e-170 yqjA S Putative aromatic acid exporter C-terminal domain
HKKPOGGN_01037 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKPOGGN_01038 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HKKPOGGN_01039 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
HKKPOGGN_01040 1.7e-75 yqiW S Belongs to the UPF0403 family
HKKPOGGN_01041 7e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKKPOGGN_01042 2.8e-190 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKPOGGN_01043 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKPOGGN_01044 5.4e-157 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKPOGGN_01045 2e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKPOGGN_01046 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
HKKPOGGN_01047 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKPOGGN_01048 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HKKPOGGN_01049 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HKKPOGGN_01050 3.2e-34 yqzF S Protein of unknown function (DUF2627)
HKKPOGGN_01051 2.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HKKPOGGN_01052 3e-278 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HKKPOGGN_01053 1.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HKKPOGGN_01054 6.7e-204 mmgC I acyl-CoA dehydrogenase
HKKPOGGN_01055 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
HKKPOGGN_01056 1.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
HKKPOGGN_01057 1.9e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKPOGGN_01058 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HKKPOGGN_01059 9.4e-17
HKKPOGGN_01060 1.5e-101 ytaF P Probably functions as a manganese efflux pump
HKKPOGGN_01061 1.2e-112 K Protein of unknown function (DUF1232)
HKKPOGGN_01063 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HKKPOGGN_01066 3.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKKPOGGN_01067 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HKKPOGGN_01068 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
HKKPOGGN_01069 3.5e-305 recN L May be involved in recombinational repair of damaged DNA
HKKPOGGN_01070 3.9e-78 argR K Regulates arginine biosynthesis genes
HKKPOGGN_01071 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HKKPOGGN_01072 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKKPOGGN_01073 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKKPOGGN_01074 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKKPOGGN_01075 8.7e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKKPOGGN_01076 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKKPOGGN_01077 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKKPOGGN_01078 8.1e-67 yqhY S protein conserved in bacteria
HKKPOGGN_01079 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKKPOGGN_01080 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKKPOGGN_01081 2.5e-62 spoIIIAH S SpoIIIAH-like protein
HKKPOGGN_01082 9.4e-116 spoIIIAG S stage III sporulation protein AG
HKKPOGGN_01083 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HKKPOGGN_01084 2.4e-199 spoIIIAE S stage III sporulation protein AE
HKKPOGGN_01085 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HKKPOGGN_01086 7.6e-29 spoIIIAC S stage III sporulation protein AC
HKKPOGGN_01087 1.6e-83 spoIIIAB S Stage III sporulation protein
HKKPOGGN_01088 2.7e-171 spoIIIAA S stage III sporulation protein AA
HKKPOGGN_01089 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HKKPOGGN_01090 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKKPOGGN_01091 5.6e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKKPOGGN_01092 1.8e-87 yqhR S Conserved membrane protein YqhR
HKKPOGGN_01093 8e-174 yqhQ S Protein of unknown function (DUF1385)
HKKPOGGN_01094 3.4e-62 yqhP
HKKPOGGN_01095 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HKKPOGGN_01096 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HKKPOGGN_01097 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HKKPOGGN_01098 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HKKPOGGN_01099 3.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKKPOGGN_01100 7.4e-250 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKKPOGGN_01101 1.1e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HKKPOGGN_01102 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKKPOGGN_01103 9.3e-152 yqhG S Bacterial protein YqhG of unknown function
HKKPOGGN_01104 3.4e-22 sinI S Anti-repressor SinI
HKKPOGGN_01105 7.8e-55 sinR K transcriptional
HKKPOGGN_01106 9.6e-141 tasA S Cell division protein FtsN
HKKPOGGN_01107 1e-70 sipW 3.4.21.89 U Signal peptidase
HKKPOGGN_01108 4.2e-121 yqxM
HKKPOGGN_01109 1.1e-53 yqzG S Protein of unknown function (DUF3889)
HKKPOGGN_01110 2.3e-26 yqzE S YqzE-like protein
HKKPOGGN_01111 2.1e-61 S ComG operon protein 7
HKKPOGGN_01112 8.3e-76 comGF U Putative Competence protein ComGF
HKKPOGGN_01113 1.1e-18 comGE
HKKPOGGN_01114 6.9e-72 gspH NU Tfp pilus assembly protein FimT
HKKPOGGN_01115 8.9e-50 comGC U Required for transformation and DNA binding
HKKPOGGN_01116 1.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
HKKPOGGN_01117 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKKPOGGN_01118 4.1e-186 corA P Mg2 transporter protein
HKKPOGGN_01119 2.1e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKPOGGN_01120 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKPOGGN_01122 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HKKPOGGN_01123 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HKKPOGGN_01124 1.1e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKPOGGN_01125 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HKKPOGGN_01126 6.9e-50 yqgV S Thiamine-binding protein
HKKPOGGN_01127 3.9e-198 yqgU
HKKPOGGN_01128 6.7e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HKKPOGGN_01129 1.4e-178 glcK 2.7.1.2 G Glucokinase
HKKPOGGN_01130 4.4e-212 nhaC C Na H antiporter
HKKPOGGN_01131 4e-07 yqgO
HKKPOGGN_01132 3.5e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKKPOGGN_01133 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKKPOGGN_01134 1.2e-50 yqzD
HKKPOGGN_01135 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKKPOGGN_01136 2.9e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKKPOGGN_01137 8.6e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKKPOGGN_01138 4.1e-156 pstA P Phosphate transport system permease
HKKPOGGN_01139 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HKKPOGGN_01140 1.4e-156 pstS P Phosphate
HKKPOGGN_01141 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HKKPOGGN_01142 2.6e-228 yqgE EGP Major facilitator superfamily
HKKPOGGN_01143 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HKKPOGGN_01144 3e-76 yqgC S protein conserved in bacteria
HKKPOGGN_01145 1.1e-130 yqgB S Protein of unknown function (DUF1189)
HKKPOGGN_01146 5.3e-47 yqfZ M LysM domain
HKKPOGGN_01147 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKKPOGGN_01148 2.3e-52 yqfX S membrane
HKKPOGGN_01149 1.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HKKPOGGN_01150 6.4e-72 zur P Belongs to the Fur family
HKKPOGGN_01151 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_01152 9.3e-37 yqfT S Protein of unknown function (DUF2624)
HKKPOGGN_01153 3.7e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKKPOGGN_01154 1.2e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKKPOGGN_01155 6.2e-51 yqfQ S YqfQ-like protein
HKKPOGGN_01156 3.8e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKKPOGGN_01157 2.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKKPOGGN_01158 9.9e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKKPOGGN_01159 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HKKPOGGN_01160 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKKPOGGN_01161 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKKPOGGN_01162 1.8e-87 yaiI S Belongs to the UPF0178 family
HKKPOGGN_01163 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKKPOGGN_01164 9.9e-112 ccpN K CBS domain
HKKPOGGN_01165 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKKPOGGN_01166 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKKPOGGN_01167 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
HKKPOGGN_01168 1.8e-16 S YqzL-like protein
HKKPOGGN_01169 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKKPOGGN_01170 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKKPOGGN_01171 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKKPOGGN_01172 1.3e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKKPOGGN_01173 0.0 yqfF S membrane-associated HD superfamily hydrolase
HKKPOGGN_01174 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HKKPOGGN_01175 1.6e-216 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HKKPOGGN_01176 9.3e-46 yqfC S sporulation protein YqfC
HKKPOGGN_01177 8.7e-51 yqfB
HKKPOGGN_01178 5.3e-120 yqfA S UPF0365 protein
HKKPOGGN_01179 1.1e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HKKPOGGN_01180 1.2e-68 yqeY S Yqey-like protein
HKKPOGGN_01181 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKKPOGGN_01182 2.3e-157 yqeW P COG1283 Na phosphate symporter
HKKPOGGN_01183 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HKKPOGGN_01184 4.7e-124 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKKPOGGN_01185 2.3e-173 prmA J Methylates ribosomal protein L11
HKKPOGGN_01186 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKKPOGGN_01187 0.0 dnaK O Heat shock 70 kDa protein
HKKPOGGN_01188 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKKPOGGN_01189 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKKPOGGN_01190 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKKPOGGN_01191 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKKPOGGN_01192 3.8e-54 yqxA S Protein of unknown function (DUF3679)
HKKPOGGN_01193 1.4e-220 spoIIP M stage II sporulation protein P
HKKPOGGN_01194 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HKKPOGGN_01195 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HKKPOGGN_01196 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HKKPOGGN_01197 9e-15 S YqzM-like protein
HKKPOGGN_01198 0.0 comEC S Competence protein ComEC
HKKPOGGN_01199 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HKKPOGGN_01200 2.4e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HKKPOGGN_01201 1.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKPOGGN_01202 2.1e-137 yqeM Q Methyltransferase
HKKPOGGN_01203 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKKPOGGN_01204 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HKKPOGGN_01205 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKKPOGGN_01206 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HKKPOGGN_01207 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKKPOGGN_01208 1.1e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKKPOGGN_01209 2e-94 yqeG S hydrolase of the HAD superfamily
HKKPOGGN_01211 2.9e-139 yqeF E GDSL-like Lipase/Acylhydrolase
HKKPOGGN_01212 4e-141 3.5.1.104 G Polysaccharide deacetylase
HKKPOGGN_01213 2.7e-106 yqeD S SNARE associated Golgi protein
HKKPOGGN_01214 1.6e-24 2.3.1.57 K Acetyltransferase (GNAT) domain
HKKPOGGN_01215 2.2e-219 EGP Major facilitator Superfamily
HKKPOGGN_01216 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_01217 9.2e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HKKPOGGN_01218 2e-89 K Transcriptional regulator PadR-like family
HKKPOGGN_01220 4.8e-149 ydeE K AraC family transcriptional regulator
HKKPOGGN_01221 2.6e-97 adk 2.7.4.3 F adenylate kinase activity
HKKPOGGN_01222 1.3e-37 tetL EGP Major facilitator Superfamily
HKKPOGGN_01223 1.2e-110 tetL EGP Major facilitator Superfamily
HKKPOGGN_01224 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
HKKPOGGN_01225 9.9e-91 yrdA S DinB family
HKKPOGGN_01226 1.2e-146 S hydrolase
HKKPOGGN_01227 3.3e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HKKPOGGN_01228 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
HKKPOGGN_01229 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKKPOGGN_01230 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HKKPOGGN_01231 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HKKPOGGN_01232 7.6e-182 romA S Beta-lactamase superfamily domain
HKKPOGGN_01233 2.8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKKPOGGN_01234 6.9e-164 yybE K Transcriptional regulator
HKKPOGGN_01235 1.3e-213 ynfM EGP Major facilitator Superfamily
HKKPOGGN_01236 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKKPOGGN_01237 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HKKPOGGN_01238 6.7e-93 yrhH Q methyltransferase
HKKPOGGN_01240 8e-143 focA P Formate nitrite
HKKPOGGN_01241 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HKKPOGGN_01242 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HKKPOGGN_01243 4.5e-80 yrhD S Protein of unknown function (DUF1641)
HKKPOGGN_01244 1.8e-34 yrhC S YrhC-like protein
HKKPOGGN_01245 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKPOGGN_01246 3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HKKPOGGN_01247 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKKPOGGN_01248 1.1e-115 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HKKPOGGN_01249 1.2e-26 yrzA S Protein of unknown function (DUF2536)
HKKPOGGN_01250 8.9e-69 yrrS S Protein of unknown function (DUF1510)
HKKPOGGN_01251 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HKKPOGGN_01252 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKKPOGGN_01253 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HKKPOGGN_01254 6.1e-246 yegQ O COG0826 Collagenase and related proteases
HKKPOGGN_01255 1.1e-172 yegQ O Peptidase U32
HKKPOGGN_01256 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
HKKPOGGN_01257 2.6e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKKPOGGN_01258 7.1e-46 yrzB S Belongs to the UPF0473 family
HKKPOGGN_01259 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKKPOGGN_01260 1.7e-41 yrzL S Belongs to the UPF0297 family
HKKPOGGN_01261 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKKPOGGN_01262 6.4e-164 yrrI S AI-2E family transporter
HKKPOGGN_01263 2.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKPOGGN_01264 5.5e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
HKKPOGGN_01265 2.7e-109 gluC P ABC transporter
HKKPOGGN_01266 1.7e-106 glnP P ABC transporter
HKKPOGGN_01267 2.1e-08 S Protein of unknown function (DUF3918)
HKKPOGGN_01268 2.9e-30 yrzR
HKKPOGGN_01269 3.4e-82 yrrD S protein conserved in bacteria
HKKPOGGN_01270 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKKPOGGN_01271 1.7e-18 S COG0457 FOG TPR repeat
HKKPOGGN_01272 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKKPOGGN_01273 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
HKKPOGGN_01274 7.8e-64 cymR K Transcriptional regulator
HKKPOGGN_01275 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKKPOGGN_01276 2.5e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HKKPOGGN_01277 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKKPOGGN_01278 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKKPOGGN_01281 6.9e-276 lytH 3.5.1.28 M COG3103 SH3 domain protein
HKKPOGGN_01282 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKKPOGGN_01283 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKKPOGGN_01284 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKKPOGGN_01285 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKKPOGGN_01286 1.7e-46 yrvD S Lipopolysaccharide assembly protein A domain
HKKPOGGN_01287 9.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKKPOGGN_01288 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKKPOGGN_01289 4.2e-49 yrzD S Post-transcriptional regulator
HKKPOGGN_01290 9.4e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_01291 9.5e-110 yrbG S membrane
HKKPOGGN_01292 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HKKPOGGN_01293 5.6e-37 yajC U Preprotein translocase subunit YajC
HKKPOGGN_01294 8.8e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKKPOGGN_01295 4.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKKPOGGN_01296 1.6e-20 yrzS S Protein of unknown function (DUF2905)
HKKPOGGN_01297 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKKPOGGN_01298 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKKPOGGN_01299 1.4e-92 bofC S BofC C-terminal domain
HKKPOGGN_01301 4.7e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKPOGGN_01302 5.7e-145 safA M spore coat assembly protein SafA
HKKPOGGN_01303 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKKPOGGN_01304 2.9e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HKKPOGGN_01305 7.6e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HKKPOGGN_01306 2.8e-221 nifS 2.8.1.7 E Cysteine desulfurase
HKKPOGGN_01307 3e-93 niaR S small molecule binding protein (contains 3H domain)
HKKPOGGN_01308 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HKKPOGGN_01309 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HKKPOGGN_01310 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKKPOGGN_01311 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HKKPOGGN_01312 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKKPOGGN_01313 3.2e-56 ysxB J ribosomal protein
HKKPOGGN_01314 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKKPOGGN_01315 7.8e-160 spoIVFB S Stage IV sporulation protein
HKKPOGGN_01316 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HKKPOGGN_01317 8e-143 minD D Belongs to the ParA family
HKKPOGGN_01318 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKKPOGGN_01319 1.4e-84 mreD M shape-determining protein
HKKPOGGN_01320 1.2e-157 mreC M Involved in formation and maintenance of cell shape
HKKPOGGN_01321 4e-184 mreB D Rod shape-determining protein MreB
HKKPOGGN_01322 1.8e-127 radC E Belongs to the UPF0758 family
HKKPOGGN_01323 3.8e-99 maf D septum formation protein Maf
HKKPOGGN_01324 4.3e-138 spoIIB S Sporulation related domain
HKKPOGGN_01325 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HKKPOGGN_01326 8.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKKPOGGN_01327 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKKPOGGN_01328 6.1e-25
HKKPOGGN_01329 1.6e-196 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HKKPOGGN_01330 6.2e-138 spoVID M stage VI sporulation protein D
HKKPOGGN_01331 5.8e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKKPOGGN_01332 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HKKPOGGN_01333 2.3e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKKPOGGN_01334 1.3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKKPOGGN_01335 3.6e-146 hemX O cytochrome C
HKKPOGGN_01336 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKKPOGGN_01337 1.5e-88 ysxD
HKKPOGGN_01338 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HKKPOGGN_01339 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HKKPOGGN_01340 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HKKPOGGN_01341 2.2e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKKPOGGN_01342 3.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKKPOGGN_01343 1.6e-188 ysoA H Tetratricopeptide repeat
HKKPOGGN_01344 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKKPOGGN_01345 2.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKKPOGGN_01346 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKKPOGGN_01347 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKKPOGGN_01348 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKKPOGGN_01349 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HKKPOGGN_01350 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HKKPOGGN_01354 1.5e-13 L Phage integrase family
HKKPOGGN_01357 4.5e-91 ysnB S Phosphoesterase
HKKPOGGN_01358 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKKPOGGN_01359 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKKPOGGN_01360 3.1e-198 gerM S COG5401 Spore germination protein
HKKPOGGN_01361 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKKPOGGN_01362 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_01363 2e-30 gerE K Transcriptional regulator
HKKPOGGN_01364 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HKKPOGGN_01365 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKKPOGGN_01366 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKKPOGGN_01367 4.8e-108 sdhC C succinate dehydrogenase
HKKPOGGN_01368 1.2e-79 yslB S Protein of unknown function (DUF2507)
HKKPOGGN_01369 1.2e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKKPOGGN_01370 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKKPOGGN_01371 2.5e-52 trxA O Belongs to the thioredoxin family
HKKPOGGN_01372 8.6e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKKPOGGN_01373 2.1e-177 etfA C Electron transfer flavoprotein
HKKPOGGN_01374 7.5e-138 etfB C Electron transfer flavoprotein
HKKPOGGN_01375 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKKPOGGN_01376 9.2e-104 fadR K Transcriptional regulator
HKKPOGGN_01377 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKKPOGGN_01378 5e-122 ywbB S Protein of unknown function (DUF2711)
HKKPOGGN_01379 4.7e-67 yshE S membrane
HKKPOGGN_01380 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKKPOGGN_01381 0.0 polX L COG1796 DNA polymerase IV (family X)
HKKPOGGN_01382 1.6e-83 cvpA S membrane protein, required for colicin V production
HKKPOGGN_01383 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKKPOGGN_01384 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKKPOGGN_01385 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKKPOGGN_01386 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKKPOGGN_01387 1.8e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKKPOGGN_01388 2e-32 sspI S Belongs to the SspI family
HKKPOGGN_01389 3.4e-205 ysfB KT regulator
HKKPOGGN_01390 3.5e-258 glcD 1.1.3.15 C FAD binding domain
HKKPOGGN_01391 6.4e-254 glcF C Glycolate oxidase
HKKPOGGN_01392 0.0 cstA T Carbon starvation protein
HKKPOGGN_01393 7.8e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HKKPOGGN_01394 1.2e-144 araQ G transport system permease
HKKPOGGN_01395 4.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HKKPOGGN_01396 2e-252 araN G carbohydrate transport
HKKPOGGN_01397 2.7e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HKKPOGGN_01398 5.1e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HKKPOGGN_01399 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKKPOGGN_01400 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HKKPOGGN_01401 1.3e-295 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKKPOGGN_01402 2.6e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKPOGGN_01403 5.3e-206 ysdC G COG1363 Cellulase M and related proteins
HKKPOGGN_01404 1.7e-66 ysdB S Sigma-w pathway protein YsdB
HKKPOGGN_01405 7e-43 ysdA S Membrane
HKKPOGGN_01406 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKKPOGGN_01407 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKKPOGGN_01408 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKKPOGGN_01409 6.4e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKKPOGGN_01410 9.1e-40 lrgA S effector of murein hydrolase LrgA
HKKPOGGN_01411 4.2e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HKKPOGGN_01412 0.0 lytS 2.7.13.3 T Histidine kinase
HKKPOGGN_01413 3.5e-151 ysaA S HAD-hyrolase-like
HKKPOGGN_01414 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKKPOGGN_01415 4e-153 ytxC S YtxC-like family
HKKPOGGN_01416 3.9e-108 ytxB S SNARE associated Golgi protein
HKKPOGGN_01417 9.5e-172 dnaI L Primosomal protein DnaI
HKKPOGGN_01418 1.3e-257 dnaB L Membrane attachment protein
HKKPOGGN_01419 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKKPOGGN_01420 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HKKPOGGN_01421 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKKPOGGN_01422 5.9e-67 ytcD K Transcriptional regulator
HKKPOGGN_01423 1.1e-204 ytbD EGP Major facilitator Superfamily
HKKPOGGN_01424 7.6e-160 ytbE S reductase
HKKPOGGN_01425 3.4e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKKPOGGN_01426 9.5e-107 ytaF P Probably functions as a manganese efflux pump
HKKPOGGN_01427 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKKPOGGN_01428 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKKPOGGN_01430 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HKKPOGGN_01431 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_01432 1.4e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HKKPOGGN_01433 1.2e-241 icd 1.1.1.42 C isocitrate
HKKPOGGN_01434 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HKKPOGGN_01435 8.5e-48 yjdF S Protein of unknown function (DUF2992)
HKKPOGGN_01436 2.5e-72 yeaL S membrane
HKKPOGGN_01437 1.1e-193 ytvI S sporulation integral membrane protein YtvI
HKKPOGGN_01438 3.5e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HKKPOGGN_01439 6.4e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKKPOGGN_01440 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKKPOGGN_01441 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKKPOGGN_01442 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKKPOGGN_01443 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HKKPOGGN_01444 0.0 dnaE 2.7.7.7 L DNA polymerase
HKKPOGGN_01445 3.2e-56 ytrH S Sporulation protein YtrH
HKKPOGGN_01446 5.1e-87 ytrI
HKKPOGGN_01447 9.8e-23
HKKPOGGN_01448 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HKKPOGGN_01449 1.5e-46 ytpI S YtpI-like protein
HKKPOGGN_01450 2.8e-238 ytoI K transcriptional regulator containing CBS domains
HKKPOGGN_01451 1.1e-129 ytkL S Belongs to the UPF0173 family
HKKPOGGN_01452 1e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_01454 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HKKPOGGN_01455 3.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKKPOGGN_01456 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HKKPOGGN_01457 3.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKKPOGGN_01458 1.1e-181 ytxK 2.1.1.72 L DNA methylase
HKKPOGGN_01459 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKKPOGGN_01460 1.6e-60 ytfJ S Sporulation protein YtfJ
HKKPOGGN_01461 1.6e-107 ytfI S Protein of unknown function (DUF2953)
HKKPOGGN_01462 2.9e-87 yteJ S RDD family
HKKPOGGN_01463 1.9e-181 sppA OU signal peptide peptidase SppA
HKKPOGGN_01464 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKKPOGGN_01465 0.0 ytcJ S amidohydrolase
HKKPOGGN_01466 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKKPOGGN_01467 3.9e-31 sspB S spore protein
HKKPOGGN_01468 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKKPOGGN_01469 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HKKPOGGN_01470 3.1e-240 braB E Component of the transport system for branched-chain amino acids
HKKPOGGN_01471 4.7e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKKPOGGN_01472 1.9e-152 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKKPOGGN_01473 2.2e-108 yttP K Transcriptional regulator
HKKPOGGN_01474 7.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HKKPOGGN_01475 1.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HKKPOGGN_01476 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKKPOGGN_01477 4e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKKPOGGN_01478 3.8e-07 S aspartate phosphatase
HKKPOGGN_01481 1.5e-23
HKKPOGGN_01482 4.1e-17 L Integrase
HKKPOGGN_01483 1.2e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKKPOGGN_01484 2.5e-09
HKKPOGGN_01485 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
HKKPOGGN_01487 6.6e-139 E GDSL-like Lipase/Acylhydrolase family
HKKPOGGN_01489 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKPOGGN_01490 4.4e-149 K Transcriptional regulator
HKKPOGGN_01491 3.4e-124 azlC E AzlC protein
HKKPOGGN_01492 2.5e-47 azlD S Branched-chain amino acid transport protein (AzlD)
HKKPOGGN_01493 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKKPOGGN_01494 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKKPOGGN_01495 1.2e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HKKPOGGN_01496 1e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
HKKPOGGN_01497 3.3e-230 acuC BQ histone deacetylase
HKKPOGGN_01498 8.2e-120 motS N Flagellar motor protein
HKKPOGGN_01499 1.5e-144 motA N flagellar motor
HKKPOGGN_01500 6.4e-182 ccpA K catabolite control protein A
HKKPOGGN_01501 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HKKPOGGN_01502 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
HKKPOGGN_01503 1.7e-16 ytxH S COG4980 Gas vesicle protein
HKKPOGGN_01504 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKKPOGGN_01505 8.4e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKKPOGGN_01506 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKKPOGGN_01507 5.3e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKKPOGGN_01508 3.7e-148 ytpQ S Belongs to the UPF0354 family
HKKPOGGN_01509 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKKPOGGN_01510 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HKKPOGGN_01511 2.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HKKPOGGN_01512 1.7e-51 ytzB S small secreted protein
HKKPOGGN_01513 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HKKPOGGN_01514 2.5e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKPOGGN_01515 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKKPOGGN_01516 3.5e-45 ytzH S YtzH-like protein
HKKPOGGN_01517 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HKKPOGGN_01518 5.2e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKKPOGGN_01519 3.4e-169 ytlQ
HKKPOGGN_01520 5.2e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HKKPOGGN_01521 6.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKKPOGGN_01522 3.9e-270 pepV 3.5.1.18 E Dipeptidase
HKKPOGGN_01523 4.5e-228 pbuO S permease
HKKPOGGN_01524 6.2e-213 ythQ U Bacterial ABC transporter protein EcsB
HKKPOGGN_01525 1.7e-128 ythP V ABC transporter
HKKPOGGN_01526 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HKKPOGGN_01527 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKKPOGGN_01528 3.8e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_01529 9.7e-236 ytfP S HI0933-like protein
HKKPOGGN_01530 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKKPOGGN_01531 9e-26 yteV S Sporulation protein Cse60
HKKPOGGN_01532 1.7e-185 msmR K Transcriptional regulator
HKKPOGGN_01533 8.8e-245 msmE G Bacterial extracellular solute-binding protein
HKKPOGGN_01534 1.8e-167 amyD G Binding-protein-dependent transport system inner membrane component
HKKPOGGN_01535 1.4e-142 amyC P ABC transporter (permease)
HKKPOGGN_01536 5.4e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKKPOGGN_01537 1.3e-84 M Acetyltransferase (GNAT) domain
HKKPOGGN_01538 1.3e-51 ytwF P Sulfurtransferase
HKKPOGGN_01539 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKKPOGGN_01540 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HKKPOGGN_01541 4.4e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HKKPOGGN_01542 4e-207 yttB EGP Major facilitator Superfamily
HKKPOGGN_01543 1e-125 ywaF S Integral membrane protein
HKKPOGGN_01544 0.0 bceB V ABC transporter (permease)
HKKPOGGN_01545 9.8e-135 bceA V ABC transporter, ATP-binding protein
HKKPOGGN_01546 1.7e-163 T PhoQ Sensor
HKKPOGGN_01547 5.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_01548 4.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKKPOGGN_01549 1.3e-125 ytrE V ABC transporter, ATP-binding protein
HKKPOGGN_01550 2.2e-158
HKKPOGGN_01551 1.7e-174 P ABC-2 family transporter protein
HKKPOGGN_01552 5.9e-172 S ABC-2 family transporter protein
HKKPOGGN_01553 3.8e-162 ytrB P abc transporter atp-binding protein
HKKPOGGN_01554 3.9e-66 ytrA K GntR family transcriptional regulator
HKKPOGGN_01555 1.3e-39 ytzC S Protein of unknown function (DUF2524)
HKKPOGGN_01556 2.1e-190 yhcC S Fe-S oxidoreductase
HKKPOGGN_01557 8.7e-107 ytqB J Putative rRNA methylase
HKKPOGGN_01559 2.7e-138 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HKKPOGGN_01560 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HKKPOGGN_01561 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HKKPOGGN_01562 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKKPOGGN_01563 4.8e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_01564 0.0 asnB 6.3.5.4 E Asparagine synthase
HKKPOGGN_01565 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKKPOGGN_01566 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKKPOGGN_01567 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HKKPOGGN_01568 1.5e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HKKPOGGN_01569 6.2e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HKKPOGGN_01570 1e-142 ytlC P ABC transporter
HKKPOGGN_01571 4.6e-122 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKKPOGGN_01572 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HKKPOGGN_01573 1.7e-61 ytkC S Bacteriophage holin family
HKKPOGGN_01574 1.6e-76 dps P Belongs to the Dps family
HKKPOGGN_01576 1.4e-75 ytkA S YtkA-like
HKKPOGGN_01577 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKKPOGGN_01578 8.9e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKKPOGGN_01579 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKKPOGGN_01580 1.6e-41 rpmE2 J Ribosomal protein L31
HKKPOGGN_01581 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HKKPOGGN_01582 8.9e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HKKPOGGN_01583 2.3e-24 S Domain of Unknown Function (DUF1540)
HKKPOGGN_01584 2.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HKKPOGGN_01585 2.9e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKKPOGGN_01586 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKKPOGGN_01587 1.9e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HKKPOGGN_01588 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKKPOGGN_01589 1e-270 menF 5.4.4.2 HQ Isochorismate synthase
HKKPOGGN_01590 1.7e-131 dksA T COG1734 DnaK suppressor protein
HKKPOGGN_01591 4.9e-76 tspO T membrane
HKKPOGGN_01600 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HKKPOGGN_01601 3.9e-133 yobQ K helix_turn_helix, arabinose operon control protein
HKKPOGGN_01602 5.4e-93 yobS K Transcriptional regulator
HKKPOGGN_01603 8.5e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKPOGGN_01604 1.9e-92 yobW
HKKPOGGN_01605 1.7e-54 czrA K transcriptional
HKKPOGGN_01606 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKKPOGGN_01607 6.9e-90 yozB S membrane
HKKPOGGN_01608 6.8e-139 yocB J Protein required for attachment to host cells
HKKPOGGN_01609 2.5e-94 yocC
HKKPOGGN_01610 9.9e-188 yocD 3.4.17.13 V peptidase S66
HKKPOGGN_01612 2.2e-114 yocH CBM50 M COG1388 FOG LysM repeat
HKKPOGGN_01613 0.0 recQ 3.6.4.12 L DNA helicase
HKKPOGGN_01614 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKKPOGGN_01616 5.9e-56 dksA T general stress protein
HKKPOGGN_01617 7.8e-10 yocL
HKKPOGGN_01618 1.7e-08
HKKPOGGN_01619 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HKKPOGGN_01620 3.8e-44 yozN
HKKPOGGN_01621 8.5e-37 yocN
HKKPOGGN_01622 2.4e-56 yozO S Bacterial PH domain
HKKPOGGN_01624 1.6e-31 yozC
HKKPOGGN_01625 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HKKPOGGN_01626 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HKKPOGGN_01627 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
HKKPOGGN_01628 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKKPOGGN_01629 1.9e-159 yocS S -transporter
HKKPOGGN_01630 8.2e-142 S Metallo-beta-lactamase superfamily
HKKPOGGN_01631 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HKKPOGGN_01632 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HKKPOGGN_01633 0.0 yojO P Von Willebrand factor
HKKPOGGN_01634 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HKKPOGGN_01635 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKKPOGGN_01636 4.4e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKPOGGN_01637 1.1e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HKKPOGGN_01638 1.8e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKKPOGGN_01640 4.4e-242 norM V Multidrug efflux pump
HKKPOGGN_01641 1.7e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKPOGGN_01642 2.5e-126 yojG S deacetylase
HKKPOGGN_01643 9.7e-61 yojF S Protein of unknown function (DUF1806)
HKKPOGGN_01644 4.9e-23
HKKPOGGN_01645 2e-163 rarD S -transporter
HKKPOGGN_01646 1.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
HKKPOGGN_01648 5.9e-67 yodA S tautomerase
HKKPOGGN_01649 2.5e-67 yoaQ S Evidence 4 Homologs of previously reported genes of
HKKPOGGN_01650 3e-56 yodB K transcriptional
HKKPOGGN_01651 4.5e-106 yodC C nitroreductase
HKKPOGGN_01652 1.4e-94 mhqD S Carboxylesterase
HKKPOGGN_01653 1.7e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HKKPOGGN_01654 1.8e-19 S Protein of unknown function (DUF3311)
HKKPOGGN_01655 4.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKPOGGN_01656 7.7e-285 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HKKPOGGN_01657 6.6e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKPOGGN_01658 3.7e-131 yydK K Transcriptional regulator
HKKPOGGN_01659 2.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKKPOGGN_01660 1.8e-127 yodH Q Methyltransferase
HKKPOGGN_01661 4.3e-34 yodI
HKKPOGGN_01662 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKKPOGGN_01663 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKKPOGGN_01665 3.3e-55 yodL S YodL-like
HKKPOGGN_01666 2e-101 yodM 3.6.1.27 I Acid phosphatase homologues
HKKPOGGN_01667 6.2e-24 yozD S YozD-like protein
HKKPOGGN_01669 1.7e-125 yodN
HKKPOGGN_01670 4.1e-36 yozE S Belongs to the UPF0346 family
HKKPOGGN_01671 4.6e-45 yokU S YokU-like protein, putative antitoxin
HKKPOGGN_01672 1.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
HKKPOGGN_01673 3.6e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HKKPOGGN_01674 5.3e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
HKKPOGGN_01675 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKKPOGGN_01676 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKKPOGGN_01677 1.3e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKPOGGN_01678 1.4e-64 yosT L Bacterial transcription activator, effector binding domain
HKKPOGGN_01680 2.9e-145 yiiD K acetyltransferase
HKKPOGGN_01681 2.2e-248 cgeD M maturation of the outermost layer of the spore
HKKPOGGN_01682 2.1e-40 cgeC
HKKPOGGN_01683 4.9e-54 cgeA
HKKPOGGN_01684 6.1e-182 cgeB S Spore maturation protein
HKKPOGGN_01685 2e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HKKPOGGN_01686 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
HKKPOGGN_01688 9.5e-19 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKKPOGGN_01692 5.3e-75 yoqH M LysM domain
HKKPOGGN_01693 9.6e-195 S aspartate phosphatase
HKKPOGGN_01695 1e-42 3.4.24.40 S amine dehydrogenase activity
HKKPOGGN_01696 1.1e-24
HKKPOGGN_01697 1.2e-44 S Acetyltransferase (GNAT) domain
HKKPOGGN_01698 3.6e-78 yokK S SMI1 / KNR4 family
HKKPOGGN_01699 9.2e-89 yokJ S SMI1 / KNR4 family (SUKH-1)
HKKPOGGN_01700 5.3e-253 UW nuclease activity
HKKPOGGN_01701 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_01702 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HKKPOGGN_01703 2.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
HKKPOGGN_01704 8.7e-246 yoeA V MATE efflux family protein
HKKPOGGN_01705 2.5e-95 yoeB S IseA DL-endopeptidase inhibitor
HKKPOGGN_01707 3.5e-97 L Integrase
HKKPOGGN_01708 1.8e-34 yoeD G Helix-turn-helix domain
HKKPOGGN_01709 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKKPOGGN_01710 3.6e-200 ybcL EGP Major facilitator Superfamily
HKKPOGGN_01711 5.1e-50 ybzH K Helix-turn-helix domain
HKKPOGGN_01712 7e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKKPOGGN_01713 2e-155 gltR1 K Transcriptional regulator
HKKPOGGN_01714 2.3e-43 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKKPOGGN_01715 7e-104 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKKPOGGN_01716 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HKKPOGGN_01717 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HKKPOGGN_01718 3.9e-146 gltC K Transcriptional regulator
HKKPOGGN_01719 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKKPOGGN_01720 7.4e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKPOGGN_01721 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HKKPOGGN_01722 1.2e-124 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_01723 4.1e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKKPOGGN_01724 5.3e-136 yoxB
HKKPOGGN_01725 1.9e-204 yoaB EGP Major facilitator Superfamily
HKKPOGGN_01726 6.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HKKPOGGN_01727 2.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKPOGGN_01728 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKPOGGN_01729 1.4e-15 yoaF
HKKPOGGN_01731 1.5e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_01732 1.3e-42
HKKPOGGN_01733 8.9e-86 S SMI1-KNR4 cell-wall
HKKPOGGN_01734 0.0 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKKPOGGN_01735 2.2e-17 G SMI1-KNR4 cell-wall
HKKPOGGN_01736 8e-53 G SMI1-KNR4 cell-wall
HKKPOGGN_01737 1.6e-76 yokF 3.1.31.1 L RNA catabolic process
HKKPOGGN_01738 1.4e-303 yokA L Recombinase
HKKPOGGN_01739 5.8e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
HKKPOGGN_01740 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKKPOGGN_01741 4.6e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKKPOGGN_01742 1.4e-66 ypoP K transcriptional
HKKPOGGN_01743 1.6e-97 ypmS S protein conserved in bacteria
HKKPOGGN_01744 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
HKKPOGGN_01745 6.1e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HKKPOGGN_01746 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HKKPOGGN_01747 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKKPOGGN_01748 2.6e-175 pspF K Transcriptional regulator
HKKPOGGN_01749 2.7e-109 hlyIII S protein, Hemolysin III
HKKPOGGN_01750 5.5e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKKPOGGN_01751 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKKPOGGN_01752 3.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKKPOGGN_01753 4.5e-114 ypjP S YpjP-like protein
HKKPOGGN_01754 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HKKPOGGN_01755 1e-75 yphP S Belongs to the UPF0403 family
HKKPOGGN_01756 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKKPOGGN_01757 4.9e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
HKKPOGGN_01758 1.8e-99 ypgQ S phosphohydrolase
HKKPOGGN_01759 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKKPOGGN_01760 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKKPOGGN_01761 1.6e-213 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HKKPOGGN_01762 7.9e-31 cspD K Cold-shock protein
HKKPOGGN_01763 1.3e-11 degR
HKKPOGGN_01764 1.2e-36 S Protein of unknown function (DUF2564)
HKKPOGGN_01765 1.5e-28 ypeQ S Zinc-finger
HKKPOGGN_01766 5.3e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HKKPOGGN_01767 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKKPOGGN_01768 1.1e-68 rnhA 3.1.26.4 L Ribonuclease
HKKPOGGN_01770 2.4e-164 polA 2.7.7.7 L 5'3' exonuclease
HKKPOGGN_01772 2.2e-38 ypbS S Protein of unknown function (DUF2533)
HKKPOGGN_01773 0.0 ypbR S Dynamin family
HKKPOGGN_01774 1.1e-89 ypbQ S protein conserved in bacteria
HKKPOGGN_01775 3.5e-205 bcsA Q Naringenin-chalcone synthase
HKKPOGGN_01776 8.6e-105 J Acetyltransferase (GNAT) domain
HKKPOGGN_01777 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HKKPOGGN_01778 8.7e-09 S Bacillus cereus group antimicrobial protein
HKKPOGGN_01779 2.6e-98 ydfR S Protein of unknown function (DUF421)
HKKPOGGN_01780 7e-101 yrdC 3.5.1.19 Q Isochorismatase family
HKKPOGGN_01782 7.2e-234 pbuX F xanthine
HKKPOGGN_01783 3.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKKPOGGN_01784 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HKKPOGGN_01785 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HKKPOGGN_01787 6.6e-22 S YpzG-like protein
HKKPOGGN_01788 1.9e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKKPOGGN_01789 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKKPOGGN_01790 4.8e-99 ypsA S Belongs to the UPF0398 family
HKKPOGGN_01791 9.9e-33 cotD S Inner spore coat protein D
HKKPOGGN_01793 1.5e-233 yprB L RNase_H superfamily
HKKPOGGN_01794 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HKKPOGGN_01795 3.9e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HKKPOGGN_01796 3.8e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HKKPOGGN_01797 2e-45 yppG S YppG-like protein
HKKPOGGN_01799 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
HKKPOGGN_01802 4.1e-186 yppC S Protein of unknown function (DUF2515)
HKKPOGGN_01803 6.1e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKKPOGGN_01804 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKKPOGGN_01805 4.3e-91 ypoC
HKKPOGGN_01806 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKKPOGGN_01807 3e-130 dnaD L DNA replication protein DnaD
HKKPOGGN_01808 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
HKKPOGGN_01809 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKKPOGGN_01810 3.4e-80 ypmB S protein conserved in bacteria
HKKPOGGN_01811 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HKKPOGGN_01812 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKKPOGGN_01813 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKKPOGGN_01814 4.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKKPOGGN_01815 1.2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKKPOGGN_01816 2.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKKPOGGN_01817 1.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKKPOGGN_01818 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HKKPOGGN_01819 1.9e-132 bshB1 S proteins, LmbE homologs
HKKPOGGN_01820 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HKKPOGGN_01821 1.6e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKKPOGGN_01822 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HKKPOGGN_01823 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_01824 6.5e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
HKKPOGGN_01825 5.1e-142 ypjB S sporulation protein
HKKPOGGN_01826 4.1e-104 ypjA S membrane
HKKPOGGN_01827 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HKKPOGGN_01828 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HKKPOGGN_01829 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HKKPOGGN_01830 1.6e-76 ypiF S Protein of unknown function (DUF2487)
HKKPOGGN_01831 2.1e-99 ypiB S Belongs to the UPF0302 family
HKKPOGGN_01832 2.7e-233 S COG0457 FOG TPR repeat
HKKPOGGN_01833 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKKPOGGN_01834 1.2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKKPOGGN_01835 1.2e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKKPOGGN_01836 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKKPOGGN_01837 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKKPOGGN_01838 1.4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKKPOGGN_01839 1e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKKPOGGN_01840 4.5e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKKPOGGN_01841 1.4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKKPOGGN_01842 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HKKPOGGN_01843 8.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKKPOGGN_01844 3.9e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKKPOGGN_01845 1.6e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HKKPOGGN_01846 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKKPOGGN_01847 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKKPOGGN_01848 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKKPOGGN_01849 1.1e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HKKPOGGN_01850 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HKKPOGGN_01851 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HKKPOGGN_01852 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKKPOGGN_01853 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HKKPOGGN_01854 1.6e-134 yphF
HKKPOGGN_01855 1.5e-16 yphE S Protein of unknown function (DUF2768)
HKKPOGGN_01856 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKKPOGGN_01857 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKKPOGGN_01858 1.1e-104 yphA
HKKPOGGN_01859 4.7e-08 S YpzI-like protein
HKKPOGGN_01860 1.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKKPOGGN_01861 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HKKPOGGN_01862 4.7e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKKPOGGN_01863 1.4e-12 S Family of unknown function (DUF5359)
HKKPOGGN_01864 3.3e-62 ypfA M Flagellar protein YcgR
HKKPOGGN_01865 3.5e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HKKPOGGN_01866 4.2e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HKKPOGGN_01867 9.2e-121 prsW S Involved in the degradation of specific anti-sigma factors
HKKPOGGN_01868 3.8e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HKKPOGGN_01869 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKPOGGN_01870 5.7e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKKPOGGN_01871 8.1e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
HKKPOGGN_01872 5.7e-85 ypbF S Protein of unknown function (DUF2663)
HKKPOGGN_01873 3e-78 ypbE M Lysin motif
HKKPOGGN_01874 9.9e-100 ypbD S metal-dependent membrane protease
HKKPOGGN_01875 1.8e-270 recQ 3.6.4.12 L DNA helicase
HKKPOGGN_01876 8.2e-196 ypbB 5.1.3.1 S protein conserved in bacteria
HKKPOGGN_01877 3.6e-41 fer C Ferredoxin
HKKPOGGN_01878 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKKPOGGN_01879 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKPOGGN_01880 1.8e-198 rsiX
HKKPOGGN_01881 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_01882 0.0 resE 2.7.13.3 T Histidine kinase
HKKPOGGN_01883 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_01884 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HKKPOGGN_01885 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HKKPOGGN_01886 7.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HKKPOGGN_01887 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKKPOGGN_01888 1.3e-88 spmB S Spore maturation protein
HKKPOGGN_01889 2e-103 spmA S Spore maturation protein
HKKPOGGN_01890 8.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HKKPOGGN_01891 3.8e-93 ypuI S Protein of unknown function (DUF3907)
HKKPOGGN_01892 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKKPOGGN_01893 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKKPOGGN_01895 3.8e-93 ypuF S Domain of unknown function (DUF309)
HKKPOGGN_01896 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKPOGGN_01897 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKKPOGGN_01898 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKKPOGGN_01899 1e-111 ribE 2.5.1.9 H Riboflavin synthase
HKKPOGGN_01900 3.6e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKKPOGGN_01901 1.7e-49 ypuD
HKKPOGGN_01902 4.5e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKPOGGN_01903 1.3e-82 ccdC1 O Protein of unknown function (DUF1453)
HKKPOGGN_01904 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKKPOGGN_01905 5.1e-154 ypuA S Secreted protein
HKKPOGGN_01906 1.7e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKKPOGGN_01907 9.2e-270 spoVAF EG Stage V sporulation protein AF
HKKPOGGN_01908 3e-110 spoVAEA S stage V sporulation protein
HKKPOGGN_01909 3.8e-57 spoVAEB S stage V sporulation protein
HKKPOGGN_01910 2.7e-188 spoVAD I Stage V sporulation protein AD
HKKPOGGN_01911 1.3e-78 spoVAC S stage V sporulation protein AC
HKKPOGGN_01912 3.9e-60 spoVAB S Stage V sporulation protein AB
HKKPOGGN_01913 4.8e-111 spoVAA S Stage V sporulation protein AA
HKKPOGGN_01914 1.5e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_01915 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HKKPOGGN_01916 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HKKPOGGN_01917 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HKKPOGGN_01918 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKKPOGGN_01919 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKKPOGGN_01920 3.7e-165 xerD L recombinase XerD
HKKPOGGN_01921 3.7e-37 S Protein of unknown function (DUF4227)
HKKPOGGN_01922 1.9e-80 fur P Belongs to the Fur family
HKKPOGGN_01923 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HKKPOGGN_01925 5e-34 yqkK
HKKPOGGN_01926 5.7e-22
HKKPOGGN_01927 7.7e-244 mleA 1.1.1.38 C malic enzyme
HKKPOGGN_01928 4.2e-240 mleN C Na H antiporter
HKKPOGGN_01929 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HKKPOGGN_01930 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HKKPOGGN_01931 1e-57 ansR K Transcriptional regulator
HKKPOGGN_01932 5.3e-220 yqxK 3.6.4.12 L DNA helicase
HKKPOGGN_01933 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HKKPOGGN_01935 2.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKKPOGGN_01937 3.4e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HKKPOGGN_01938 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HKKPOGGN_01939 7.7e-61 yqkB S Belongs to the HesB IscA family
HKKPOGGN_01940 4.3e-175 yqkA K GrpB protein
HKKPOGGN_01941 1.2e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HKKPOGGN_01942 3.3e-88 yqjY K acetyltransferase
HKKPOGGN_01943 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKKPOGGN_01944 7.6e-58 S YolD-like protein
HKKPOGGN_01946 1.6e-186 yueF S transporter activity
HKKPOGGN_01948 5.6e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKPOGGN_01949 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HKKPOGGN_01950 5.6e-258 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HKKPOGGN_01951 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_01952 4.5e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKPOGGN_01953 3.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKPOGGN_01954 2.2e-134 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HKKPOGGN_01955 7.1e-239 pksG 2.3.3.10 I synthase
HKKPOGGN_01956 6.8e-220 eryK 1.14.13.154 C Cytochrome P450
HKKPOGGN_01957 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKKPOGGN_01958 0.0 Q Polyketide synthase of type I
HKKPOGGN_01959 0.0 pfaA Q Polyketide synthase of type I
HKKPOGGN_01960 0.0 pksJ Q Polyketide synthase of type I
HKKPOGGN_01961 3.2e-220 glcP G Major Facilitator Superfamily
HKKPOGGN_01962 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKPOGGN_01963 5.1e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HKKPOGGN_01964 1.4e-200 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HKKPOGGN_01965 3e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKKPOGGN_01966 6.3e-174 ybaS 1.1.1.58 S Na -dependent transporter
HKKPOGGN_01967 1.6e-108 ybbA S Putative esterase
HKKPOGGN_01968 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_01969 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_01970 4.5e-169 feuA P Iron-uptake system-binding protein
HKKPOGGN_01971 2.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HKKPOGGN_01972 1.2e-235 ybbC 3.2.1.52 S protein conserved in bacteria
HKKPOGGN_01973 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HKKPOGGN_01974 4.4e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HKKPOGGN_01975 5.4e-240 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKPOGGN_01976 7.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKKPOGGN_01977 2.6e-85 ybbJ J acetyltransferase
HKKPOGGN_01978 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HKKPOGGN_01984 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_01985 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HKKPOGGN_01986 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKKPOGGN_01987 1.7e-223 ybbR S protein conserved in bacteria
HKKPOGGN_01988 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKKPOGGN_01989 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKKPOGGN_01990 3.4e-155 V ATPases associated with a variety of cellular activities
HKKPOGGN_01991 1.7e-103 S ABC-2 family transporter protein
HKKPOGGN_01992 5.3e-18 ybdN
HKKPOGGN_01993 3.8e-07 6.3.2.14 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_01994 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_01995 1.3e-185 T PhoQ Sensor
HKKPOGGN_01996 3.7e-137 V ABC transporter, ATP-binding protein
HKKPOGGN_01997 0.0 V ABC transporter (permease)
HKKPOGGN_01998 1e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKKPOGGN_01999 1.2e-162 dkgB S Aldo/keto reductase family
HKKPOGGN_02000 1e-93 yxaC M effector of murein hydrolase
HKKPOGGN_02001 6.9e-52 S LrgA family
HKKPOGGN_02002 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_02004 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_02005 1.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKKPOGGN_02006 5.3e-201 T COG4585 Signal transduction histidine kinase
HKKPOGGN_02007 1.8e-108 KT LuxR family transcriptional regulator
HKKPOGGN_02008 5.4e-167 V COG1131 ABC-type multidrug transport system, ATPase component
HKKPOGGN_02009 3.4e-206 V COG0842 ABC-type multidrug transport system, permease component
HKKPOGGN_02010 8.6e-199 V ABC-2 family transporter protein
HKKPOGGN_02011 5.8e-25
HKKPOGGN_02012 1.5e-75 S Domain of unknown function (DUF4879)
HKKPOGGN_02013 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
HKKPOGGN_02014 3.6e-107 yqeB
HKKPOGGN_02015 9.2e-40 ybyB
HKKPOGGN_02016 2.1e-291 ybeC E amino acid
HKKPOGGN_02017 1.4e-53
HKKPOGGN_02018 6.8e-16 S Protein of unknown function (DUF2651)
HKKPOGGN_02019 6.3e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKPOGGN_02020 1.7e-259 glpT G -transporter
HKKPOGGN_02021 1.3e-16 S Protein of unknown function (DUF2651)
HKKPOGGN_02022 3.6e-210 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HKKPOGGN_02024 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HKKPOGGN_02025 3.5e-31
HKKPOGGN_02026 3.5e-82 K Helix-turn-helix XRE-family like proteins
HKKPOGGN_02027 8.6e-193 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HKKPOGGN_02028 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKKPOGGN_02029 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKKPOGGN_02030 1.9e-86 ybfM S SNARE associated Golgi protein
HKKPOGGN_02031 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKKPOGGN_02032 1.2e-42 ybfN
HKKPOGGN_02033 2.3e-192 yceA S Belongs to the UPF0176 family
HKKPOGGN_02034 3.2e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKPOGGN_02035 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKKPOGGN_02036 1.5e-256 mmuP E amino acid
HKKPOGGN_02037 6.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HKKPOGGN_02038 5.1e-257 agcS E Sodium alanine symporter
HKKPOGGN_02039 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
HKKPOGGN_02040 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
HKKPOGGN_02041 1.9e-172 glnL T Regulator
HKKPOGGN_02042 7.1e-127 ycbJ S Macrolide 2'-phosphotransferase
HKKPOGGN_02043 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HKKPOGGN_02044 2.7e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKPOGGN_02045 1.4e-110 ydfN C nitroreductase
HKKPOGGN_02046 2.1e-182 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HKKPOGGN_02047 1.5e-62 mhqP S DoxX
HKKPOGGN_02048 1.2e-55 traF CO Thioredoxin
HKKPOGGN_02049 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HKKPOGGN_02050 6.3e-78 sleB 3.5.1.28 M Cell wall
HKKPOGGN_02051 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HKKPOGGN_02052 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKKPOGGN_02053 6.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKKPOGGN_02054 4.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKKPOGGN_02055 2.2e-207 ycbU E Selenocysteine lyase
HKKPOGGN_02056 1e-241 lmrB EGP the major facilitator superfamily
HKKPOGGN_02057 4.5e-100 yxaF K Transcriptional regulator
HKKPOGGN_02058 5.1e-196 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKKPOGGN_02059 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKKPOGGN_02060 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
HKKPOGGN_02061 3.6e-171 yccK C Aldo keto reductase
HKKPOGGN_02062 2.3e-176 ycdA S Domain of unknown function (DUF5105)
HKKPOGGN_02063 1.3e-257 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_02064 2.9e-262 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_02065 4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
HKKPOGGN_02066 1e-188 S response regulator aspartate phosphatase
HKKPOGGN_02067 2e-138 IQ Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_02068 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HKKPOGGN_02069 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
HKKPOGGN_02070 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKKPOGGN_02071 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKKPOGGN_02072 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_02073 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HKKPOGGN_02074 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HKKPOGGN_02075 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HKKPOGGN_02076 2.2e-137 terC P Protein of unknown function (DUF475)
HKKPOGGN_02077 0.0 yceG S Putative component of 'biosynthetic module'
HKKPOGGN_02078 2.3e-193 yceH P Belongs to the TelA family
HKKPOGGN_02079 4e-215 naiP P Uncharacterised MFS-type transporter YbfB
HKKPOGGN_02080 3.9e-229 proV 3.6.3.32 E glycine betaine
HKKPOGGN_02081 1.6e-138 opuAB P glycine betaine
HKKPOGGN_02082 3.1e-164 opuAC E glycine betaine
HKKPOGGN_02083 7.3e-211 amhX S amidohydrolase
HKKPOGGN_02084 1.1e-230 ycgA S Membrane
HKKPOGGN_02085 5.3e-81 ycgB
HKKPOGGN_02086 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HKKPOGGN_02087 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKKPOGGN_02088 1.2e-259 mdr EGP Major facilitator Superfamily
HKKPOGGN_02089 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_02090 3e-113 ycgF E Lysine exporter protein LysE YggA
HKKPOGGN_02091 1.6e-148 yqcI S YqcI/YcgG family
HKKPOGGN_02092 6.4e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_02093 4.9e-113 ycgI S Domain of unknown function (DUF1989)
HKKPOGGN_02094 2.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKKPOGGN_02096 4.2e-136 4.2.1.118 G Xylose isomerase-like TIM barrel
HKKPOGGN_02097 3.1e-221 G COG0477 Permeases of the major facilitator superfamily
HKKPOGGN_02098 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKKPOGGN_02099 5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HKKPOGGN_02100 2.2e-142 ycgL S Predicted nucleotidyltransferase
HKKPOGGN_02101 2.3e-170 ycgM E Proline dehydrogenase
HKKPOGGN_02102 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKKPOGGN_02103 2.9e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKPOGGN_02104 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HKKPOGGN_02105 6.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKKPOGGN_02106 7.1e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKKPOGGN_02107 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
HKKPOGGN_02108 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HKKPOGGN_02109 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKPOGGN_02110 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HKKPOGGN_02111 1.5e-222 nasA P COG2223 Nitrate nitrite transporter
HKKPOGGN_02112 7.1e-228 yciC S GTPases (G3E family)
HKKPOGGN_02113 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKKPOGGN_02114 3.6e-73 yckC S membrane
HKKPOGGN_02115 6.5e-51 S Protein of unknown function (DUF2680)
HKKPOGGN_02116 2.9e-69 nin S Competence protein J (ComJ)
HKKPOGGN_02117 7.1e-77 nucA M Deoxyribonuclease NucA/NucB
HKKPOGGN_02118 2.1e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKKPOGGN_02119 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HKKPOGGN_02120 6.3e-63 hxlR K transcriptional
HKKPOGGN_02121 6.4e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_02122 1.6e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_02123 7.8e-08
HKKPOGGN_02125 5.6e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKKPOGGN_02126 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HKKPOGGN_02127 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HKKPOGGN_02128 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKKPOGGN_02129 1.5e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKKPOGGN_02130 0.0 ydiF S ABC transporter
HKKPOGGN_02131 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HKKPOGGN_02132 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKKPOGGN_02133 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKKPOGGN_02134 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKKPOGGN_02135 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HKKPOGGN_02136 5.6e-127 ydiL S CAAX protease self-immunity
HKKPOGGN_02137 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKKPOGGN_02138 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKKPOGGN_02139 8.4e-150 ydjC S Abhydrolase domain containing 18
HKKPOGGN_02140 0.0 K NB-ARC domain
HKKPOGGN_02141 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
HKKPOGGN_02142 2.9e-249 gutA G MFS/sugar transport protein
HKKPOGGN_02143 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HKKPOGGN_02144 5.6e-31 yjdJ S Domain of unknown function (DUF4306)
HKKPOGGN_02145 3.9e-114 pspA KT Phage shock protein A
HKKPOGGN_02146 1.2e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKKPOGGN_02147 2.6e-119 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HKKPOGGN_02148 4.3e-146 ydjI S virion core protein (lumpy skin disease virus)
HKKPOGGN_02149 0.0 yrhL I Acyltransferase family
HKKPOGGN_02150 1.7e-146 rsiV S Protein of unknown function (DUF3298)
HKKPOGGN_02151 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_02152 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HKKPOGGN_02153 2.1e-61 ydjM M Lytic transglycolase
HKKPOGGN_02154 1.3e-132 ydjN U Involved in the tonB-independent uptake of proteins
HKKPOGGN_02156 7.2e-35 ydjO S Cold-inducible protein YdjO
HKKPOGGN_02157 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HKKPOGGN_02158 9.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_02159 2.1e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKPOGGN_02160 1.3e-176 yeaC S COG0714 MoxR-like ATPases
HKKPOGGN_02161 3.7e-213 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HKKPOGGN_02162 0.0 yebA E COG1305 Transglutaminase-like enzymes
HKKPOGGN_02163 2.9e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKKPOGGN_02164 9.1e-128 K Acetyltransferase (GNAT) domain
HKKPOGGN_02165 1.2e-91 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKKPOGGN_02166 9e-246 S Domain of unknown function (DUF4179)
HKKPOGGN_02167 1.1e-208 pbuG S permease
HKKPOGGN_02168 1.9e-125 yebC M Membrane
HKKPOGGN_02170 3.1e-93 yebE S UPF0316 protein
HKKPOGGN_02171 6.1e-28 yebG S NETI protein
HKKPOGGN_02172 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKKPOGGN_02173 6.1e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKKPOGGN_02174 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKKPOGGN_02175 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKKPOGGN_02176 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKPOGGN_02177 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKPOGGN_02178 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKPOGGN_02179 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKKPOGGN_02180 1e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKKPOGGN_02181 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKKPOGGN_02182 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKKPOGGN_02183 9.1e-234 purD 6.3.4.13 F Belongs to the GARS family
HKKPOGGN_02184 1.5e-25 S Protein of unknown function (DUF2892)
HKKPOGGN_02185 0.0 yerA 3.5.4.2 F adenine deaminase
HKKPOGGN_02186 9.8e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HKKPOGGN_02187 6.9e-50 yerC S protein conserved in bacteria
HKKPOGGN_02188 2.6e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HKKPOGGN_02189 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HKKPOGGN_02190 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKKPOGGN_02191 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKKPOGGN_02192 3.1e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
HKKPOGGN_02193 4.2e-194 yerI S homoserine kinase type II (protein kinase fold)
HKKPOGGN_02194 1.5e-121 sapB S MgtC SapB transporter
HKKPOGGN_02195 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKPOGGN_02196 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKKPOGGN_02197 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKKPOGGN_02198 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKKPOGGN_02199 1.1e-153 yerO K Transcriptional regulator
HKKPOGGN_02200 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKKPOGGN_02201 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKKPOGGN_02202 1.1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKKPOGGN_02203 6.1e-79 KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_02205 3.1e-33 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKKPOGGN_02206 4.5e-63 fabZ 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HKKPOGGN_02207 3.7e-194 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKKPOGGN_02208 1.7e-131 2.3.1.179 I 3-oxoacyl-[acyl-carrier-protein] synthase activity
HKKPOGGN_02209 8.5e-112 IQ reductase
HKKPOGGN_02210 6.1e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HKKPOGGN_02211 3.8e-138 cylB V ABC-2 type transporter
HKKPOGGN_02212 1.1e-35 S Protein of unknown function, DUF600
HKKPOGGN_02213 2.8e-63 S Protein of unknown function, DUF600
HKKPOGGN_02214 1e-52 S Protein of unknown function, DUF600
HKKPOGGN_02215 6.8e-46 S Protein of unknown function, DUF600
HKKPOGGN_02216 1.3e-55 S Protein of unknown function, DUF600
HKKPOGGN_02217 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
HKKPOGGN_02218 9.4e-127 yeeN K transcriptional regulatory protein
HKKPOGGN_02220 2.8e-109 aadK G Streptomycin adenylyltransferase
HKKPOGGN_02221 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
HKKPOGGN_02222 3.3e-45 cotJB S CotJB protein
HKKPOGGN_02223 8.9e-104 cotJC P Spore Coat
HKKPOGGN_02224 4.9e-96 yesJ K Acetyltransferase (GNAT) family
HKKPOGGN_02226 3.3e-121 yetF S membrane
HKKPOGGN_02227 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HKKPOGGN_02228 5.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKPOGGN_02229 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKPOGGN_02230 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HKKPOGGN_02231 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HKKPOGGN_02232 6.9e-105 yetJ S Belongs to the BI1 family
HKKPOGGN_02233 1.1e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HKKPOGGN_02234 5.4e-206 yetM CH FAD binding domain
HKKPOGGN_02235 7.5e-197 yetN S Protein of unknown function (DUF3900)
HKKPOGGN_02236 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKKPOGGN_02238 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
HKKPOGGN_02239 7.5e-166 V ATPases associated with a variety of cellular activities
HKKPOGGN_02240 1.7e-126 V ABC-2 type transporter
HKKPOGGN_02242 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKPOGGN_02243 3.9e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HKKPOGGN_02244 1.7e-170 yfnG 4.2.1.45 M dehydratase
HKKPOGGN_02245 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
HKKPOGGN_02246 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HKKPOGGN_02247 2.9e-184 yfnD M Nucleotide-diphospho-sugar transferase
HKKPOGGN_02248 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
HKKPOGGN_02249 4.3e-245 yfnA E amino acid
HKKPOGGN_02250 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKPOGGN_02251 9.8e-115 yfmS NT chemotaxis protein
HKKPOGGN_02252 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_02253 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKPOGGN_02254 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKPOGGN_02255 3.1e-69 yfmP K transcriptional
HKKPOGGN_02256 1.4e-207 yfmO EGP Major facilitator Superfamily
HKKPOGGN_02257 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKPOGGN_02258 4.6e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HKKPOGGN_02259 4.7e-17 yfmK 2.3.1.128 K acetyltransferase
HKKPOGGN_02260 2.6e-34 yfmK 2.3.1.128 K acetyltransferase
HKKPOGGN_02261 2.1e-188 yfmJ S N-terminal domain of oxidoreductase
HKKPOGGN_02262 1.2e-24 S Protein of unknown function (DUF3212)
HKKPOGGN_02263 1.3e-57 yflT S Heat induced stress protein YflT
HKKPOGGN_02264 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HKKPOGGN_02265 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
HKKPOGGN_02266 2.7e-28 Q PFAM Collagen triple helix
HKKPOGGN_02268 2e-50 Q calcium- and calmodulin-responsive adenylate cyclase activity
HKKPOGGN_02269 3.4e-75 M1-820 Q Collagen triple helix repeat (20 copies)
HKKPOGGN_02270 0.0 ywpD T PhoQ Sensor
HKKPOGGN_02271 1.9e-152 M1-574 T Transcriptional regulatory protein, C terminal
HKKPOGGN_02272 0.0 M1-568 M cell wall anchor domain
HKKPOGGN_02273 1.1e-78 srtA 3.4.22.70 M Sortase family
HKKPOGGN_02274 5.7e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKPOGGN_02275 1.8e-119 citT T response regulator
HKKPOGGN_02276 3.5e-177 yflP S Tripartite tricarboxylate transporter family receptor
HKKPOGGN_02277 3.8e-227 citM C Citrate transporter
HKKPOGGN_02278 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKPOGGN_02279 1.2e-218 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HKKPOGGN_02280 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKKPOGGN_02281 1.7e-122 yflK S protein conserved in bacteria
HKKPOGGN_02282 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HKKPOGGN_02283 9.1e-19 yflI
HKKPOGGN_02284 3.1e-50 yflH S Protein of unknown function (DUF3243)
HKKPOGGN_02285 5.2e-136 map 3.4.11.18 E Methionine aminopeptidase
HKKPOGGN_02286 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HKKPOGGN_02287 1.3e-70 yfmQ S Uncharacterised protein from bacillus cereus group
HKKPOGGN_02288 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKPOGGN_02289 7.8e-64 yhdN S Domain of unknown function (DUF1992)
HKKPOGGN_02290 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HKKPOGGN_02291 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HKKPOGGN_02292 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HKKPOGGN_02293 2.3e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKPOGGN_02294 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HKKPOGGN_02295 2.6e-129 treR K transcriptional
HKKPOGGN_02296 5.8e-123 yfkO C nitroreductase
HKKPOGGN_02297 3.5e-124 yibF S YibE/F-like protein
HKKPOGGN_02298 1.3e-199 yibE S YibE/F-like protein
HKKPOGGN_02299 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HKKPOGGN_02300 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HKKPOGGN_02301 4e-187 K helix_turn _helix lactose operon repressor
HKKPOGGN_02302 2.2e-162 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKKPOGGN_02303 4.9e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKKPOGGN_02304 1.3e-192 ydiM EGP Major facilitator Superfamily
HKKPOGGN_02305 2.7e-29 yfkK S Belongs to the UPF0435 family
HKKPOGGN_02306 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKKPOGGN_02307 2.5e-50 yfkI S gas vesicle protein
HKKPOGGN_02308 5.8e-144 yihY S Belongs to the UPF0761 family
HKKPOGGN_02309 2.5e-07
HKKPOGGN_02310 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HKKPOGGN_02311 6.5e-185 cax P COG0387 Ca2 H antiporter
HKKPOGGN_02312 2.5e-144 yfkD S YfkD-like protein
HKKPOGGN_02313 3.3e-147 yfkC M Mechanosensitive ion channel
HKKPOGGN_02314 1.7e-220 yfkA S YfkB-like domain
HKKPOGGN_02315 4.9e-27 yfjT
HKKPOGGN_02316 2.6e-154 pdaA G deacetylase
HKKPOGGN_02317 2.9e-146 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKKPOGGN_02318 7.9e-32
HKKPOGGN_02319 8.5e-184 corA P Mediates influx of magnesium ions
HKKPOGGN_02320 5.5e-158 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKKPOGGN_02321 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKKPOGGN_02323 1.6e-48 S YfzA-like protein
HKKPOGGN_02324 1.8e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKKPOGGN_02325 1.9e-87 yfjM S Psort location Cytoplasmic, score
HKKPOGGN_02326 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKPOGGN_02327 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKPOGGN_02328 8.3e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKPOGGN_02329 2.1e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKPOGGN_02330 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HKKPOGGN_02331 4.2e-15 sspH S Belongs to the SspH family
HKKPOGGN_02332 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKKPOGGN_02333 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
HKKPOGGN_02334 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKPOGGN_02335 0.0 yobO M COG5434 Endopolygalacturonase
HKKPOGGN_02336 0.0 yfiB3 V ABC transporter
HKKPOGGN_02337 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKPOGGN_02338 7e-63 mhqP S DoxX
HKKPOGGN_02339 5.9e-160 yfiE 1.13.11.2 S glyoxalase
HKKPOGGN_02340 4.6e-166 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKKPOGGN_02341 1.7e-96 padR K transcriptional
HKKPOGGN_02342 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
HKKPOGGN_02343 5e-180 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HKKPOGGN_02344 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HKKPOGGN_02345 1.5e-45 yrdF K ribonuclease inhibitor
HKKPOGGN_02346 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
HKKPOGGN_02347 1.5e-289 yfiU EGP Major facilitator Superfamily
HKKPOGGN_02348 2.8e-82 yfiV K transcriptional
HKKPOGGN_02349 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKKPOGGN_02350 6.9e-164 yfhB 5.3.3.17 S PhzF family
HKKPOGGN_02351 3.3e-106 yfhC C nitroreductase
HKKPOGGN_02352 2.3e-24 yfhD S YfhD-like protein
HKKPOGGN_02354 8.9e-167 yfhF S nucleoside-diphosphate sugar epimerase
HKKPOGGN_02355 3.9e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
HKKPOGGN_02356 3.3e-52 yfhH S Protein of unknown function (DUF1811)
HKKPOGGN_02357 1.5e-206 yfhI EGP Major facilitator Superfamily
HKKPOGGN_02359 7.6e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HKKPOGGN_02360 2.2e-44 yfhJ S WVELL protein
HKKPOGGN_02361 5.9e-94 batE T Bacterial SH3 domain homologues
HKKPOGGN_02362 1.1e-34 yfhL S SdpI/YhfL protein family
HKKPOGGN_02363 4.5e-168 yfhM S Alpha/beta hydrolase family
HKKPOGGN_02364 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKPOGGN_02365 0.0 yfhO S Bacterial membrane protein YfhO
HKKPOGGN_02366 1e-184 yfhP S membrane-bound metal-dependent
HKKPOGGN_02367 3.9e-209 mutY L A G-specific
HKKPOGGN_02368 8.2e-37 yfhS
HKKPOGGN_02369 7.5e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_02371 1.5e-37 ygaB S YgaB-like protein
HKKPOGGN_02372 2.2e-104 ygaC J Belongs to the UPF0374 family
HKKPOGGN_02373 3.5e-300 ygaD V ABC transporter
HKKPOGGN_02374 3.2e-179 ygaE S Membrane
HKKPOGGN_02375 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKKPOGGN_02376 5.9e-85 bcp 1.11.1.15 O Peroxiredoxin
HKKPOGGN_02377 1.8e-80 perR P Belongs to the Fur family
HKKPOGGN_02378 4.3e-56 ygzB S UPF0295 protein
HKKPOGGN_02379 8.2e-165 ygxA S Nucleotidyltransferase-like
HKKPOGGN_02380 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKKPOGGN_02381 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKKPOGGN_02382 8.1e-38 yaaB S Domain of unknown function (DUF370)
HKKPOGGN_02383 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKKPOGGN_02384 2.4e-33 yaaA S S4 domain
HKKPOGGN_02385 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKKPOGGN_02386 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKKPOGGN_02387 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKKPOGGN_02388 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKKPOGGN_02389 1e-108 jag S single-stranded nucleic acid binding R3H
HKKPOGGN_02390 1.2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKKPOGGN_02391 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKKPOGGN_02392 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HKKPOGGN_02393 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HKKPOGGN_02394 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
HKKPOGGN_02395 3.9e-148 spo0J K Belongs to the ParB family
HKKPOGGN_02396 6.8e-110 yyaC S Sporulation protein YyaC
HKKPOGGN_02397 3.8e-82 4.2.1.103 K FR47-like protein
HKKPOGGN_02398 2.4e-176 yyaD S Membrane
HKKPOGGN_02399 1.5e-32 yyzM S protein conserved in bacteria
HKKPOGGN_02400 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKPOGGN_02401 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKKPOGGN_02402 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HKKPOGGN_02403 4.2e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKKPOGGN_02404 4.8e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKKPOGGN_02405 1.6e-105 adaA 3.2.2.21 K Transcriptional regulator
HKKPOGGN_02406 1.5e-100 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKKPOGGN_02407 1.5e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HKKPOGGN_02408 2.8e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HKKPOGGN_02409 3.2e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKPOGGN_02410 6.2e-249 ydjK G Sugar (and other) transporter
HKKPOGGN_02411 1.3e-162 yyaK S CAAX protease self-immunity
HKKPOGGN_02412 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HKKPOGGN_02413 3.2e-162 S Patatin-like phospholipase
HKKPOGGN_02414 1.1e-132 ydfC EG EamA-like transporter family
HKKPOGGN_02415 7.4e-248 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKPOGGN_02416 1.2e-28 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HKKPOGGN_02417 5.5e-95
HKKPOGGN_02418 5e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKKPOGGN_02419 2.2e-165 K Transcriptional regulator
HKKPOGGN_02420 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKKPOGGN_02421 6.8e-164 eaeH M Domain of Unknown Function (DUF1259)
HKKPOGGN_02422 7.7e-76 yjcF S Acetyltransferase (GNAT) domain
HKKPOGGN_02423 5.6e-77 yybA 2.3.1.57 K transcriptional
HKKPOGGN_02424 3.3e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_02425 3.2e-69 ydgJ K Winged helix DNA-binding domain
HKKPOGGN_02426 5.6e-115 drgA C nitroreductase
HKKPOGGN_02427 1.4e-54 ypaA S Protein of unknown function (DUF1304)
HKKPOGGN_02428 3.1e-07 gltC K Transcriptional regulator
HKKPOGGN_02429 5.8e-161 G Major Facilitator Superfamily
HKKPOGGN_02430 5e-74 dinB S PFAM DinB family protein
HKKPOGGN_02431 1.3e-114 K FCD domain
HKKPOGGN_02432 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HKKPOGGN_02433 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HKKPOGGN_02434 1.3e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKKPOGGN_02435 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HKKPOGGN_02436 2.8e-66 ydeP3 K Transcriptional regulator
HKKPOGGN_02437 1.5e-84 cotF M Spore coat protein
HKKPOGGN_02439 1.6e-158 yybS S membrane
HKKPOGGN_02440 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKKPOGGN_02441 4.9e-73 rplI J binds to the 23S rRNA
HKKPOGGN_02442 5.8e-123 KLT COG0515 Serine threonine protein kinase
HKKPOGGN_02443 1.7e-122 S GlcNAc-PI de-N-acetylase
HKKPOGGN_02444 9.6e-242 M Glycosyltransferase Family 4
HKKPOGGN_02445 2.4e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HKKPOGGN_02446 1.2e-202 S Ecdysteroid kinase
HKKPOGGN_02447 1.2e-244 M Glycosyltransferase Family 4
HKKPOGGN_02448 3.5e-17 yycC K YycC-like protein
HKKPOGGN_02450 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HKKPOGGN_02451 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKKPOGGN_02452 5.9e-73 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKPOGGN_02453 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKKPOGGN_02458 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_02459 0.0 vicK 2.7.13.3 T Histidine kinase
HKKPOGGN_02460 2.7e-260 yycH S protein conserved in bacteria
HKKPOGGN_02461 8.3e-151 yycI S protein conserved in bacteria
HKKPOGGN_02462 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HKKPOGGN_02463 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKPOGGN_02464 9.6e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_02465 2.7e-250 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKPOGGN_02466 2.6e-191 2.7.7.73, 2.7.7.80 H ThiF family
HKKPOGGN_02467 5e-259
HKKPOGGN_02468 4.4e-198 S Major Facilitator Superfamily
HKKPOGGN_02469 3e-306 S ABC transporter
HKKPOGGN_02470 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
HKKPOGGN_02471 1.2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HKKPOGGN_02472 2.2e-42 sdpR K transcriptional
HKKPOGGN_02473 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HKKPOGGN_02474 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HKKPOGGN_02475 5.9e-258 rocE E amino acid
HKKPOGGN_02476 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HKKPOGGN_02477 5.2e-201 S Histidine kinase
HKKPOGGN_02479 8.2e-87 yycN 2.3.1.128 K Acetyltransferase
HKKPOGGN_02480 7.4e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKKPOGGN_02481 2e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKKPOGGN_02482 1.3e-213 yycP
HKKPOGGN_02484 7.9e-08 S YyzF-like protein
HKKPOGGN_02485 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKKPOGGN_02486 6e-23 V HNH endonuclease
HKKPOGGN_02487 1.8e-148 dcm_2 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
HKKPOGGN_02488 6.3e-155 dcm 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
HKKPOGGN_02490 2.7e-180 S Fusaric acid resistance protein-like
HKKPOGGN_02491 4.3e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HKKPOGGN_02492 1.4e-89 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HKKPOGGN_02493 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HKKPOGGN_02494 4e-153 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HKKPOGGN_02495 2.2e-84 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HKKPOGGN_02496 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HKKPOGGN_02497 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_02498 2.3e-287 ahpF O Alkyl hydroperoxide reductase
HKKPOGGN_02499 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HKKPOGGN_02500 4e-127 E Ring-cleavage extradiol dioxygenase
HKKPOGGN_02501 7.6e-74 yxaI S membrane protein domain
HKKPOGGN_02502 3.2e-201 EGP Major facilitator Superfamily
HKKPOGGN_02503 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKKPOGGN_02504 2.7e-65 S Family of unknown function (DUF5391)
HKKPOGGN_02505 5.2e-141 S PQQ-like domain
HKKPOGGN_02506 1.1e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKKPOGGN_02507 4.1e-217 yxbF K Bacterial regulatory proteins, tetR family
HKKPOGGN_02508 1.1e-200 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKKPOGGN_02509 5e-199 desK 2.7.13.3 T Histidine kinase
HKKPOGGN_02510 3.5e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_02511 4.8e-151 IQ Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_02513 0.0 htpG O Molecular chaperone. Has ATPase activity
HKKPOGGN_02514 2.5e-245 csbC EGP Major facilitator Superfamily
HKKPOGGN_02515 4.9e-176 iolS C Aldo keto reductase
HKKPOGGN_02516 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HKKPOGGN_02517 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKPOGGN_02518 3.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKKPOGGN_02519 1.1e-181 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKKPOGGN_02520 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKKPOGGN_02521 2.6e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKKPOGGN_02522 9.6e-231 iolF EGP Major facilitator Superfamily
HKKPOGGN_02523 4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKKPOGGN_02524 1.1e-166 iolH G Xylose isomerase-like TIM barrel
HKKPOGGN_02525 1.7e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HKKPOGGN_02526 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HKKPOGGN_02527 2.5e-130 lanT 3.6.3.27 V TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein
HKKPOGGN_02528 1.2e-181 V Domain of unknown function (DUF4135)
HKKPOGGN_02529 1.1e-37 4.1.1.36, 6.3.2.5 H Flavoprotein
HKKPOGGN_02530 5.6e-14 KT Transcriptional regulatory protein, C terminal
HKKPOGGN_02532 1.7e-128 S ABC-2 family transporter protein
HKKPOGGN_02533 1.3e-131 S permease
HKKPOGGN_02534 9.3e-164 bcrA V ABC transporter, ATP-binding protein
HKKPOGGN_02535 8.5e-136 T Transcriptional regulator
HKKPOGGN_02536 3.3e-272 T Histidine kinase
HKKPOGGN_02537 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_02538 2.1e-174 T PhoQ Sensor
HKKPOGGN_02539 5.5e-141 yxdL V ABC transporter, ATP-binding protein
HKKPOGGN_02540 0.0 yxdM V ABC transporter (permease)
HKKPOGGN_02541 5e-57 yxeA S Protein of unknown function (DUF1093)
HKKPOGGN_02542 3.9e-176 fhuD P Periplasmic binding protein
HKKPOGGN_02543 2.3e-34
HKKPOGGN_02544 1.6e-21 yxeD
HKKPOGGN_02545 6e-11 yxeE
HKKPOGGN_02548 1.5e-149 yidA S hydrolases of the HAD superfamily
HKKPOGGN_02549 3.3e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKKPOGGN_02550 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKKPOGGN_02551 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKPOGGN_02552 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HKKPOGGN_02553 3.4e-253 lysP E amino acid
HKKPOGGN_02554 1.6e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HKKPOGGN_02555 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HKKPOGGN_02556 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKKPOGGN_02557 1.1e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
HKKPOGGN_02558 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HKKPOGGN_02559 3.1e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKPOGGN_02560 7.1e-26
HKKPOGGN_02561 1.9e-62 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKPOGGN_02562 4.1e-72 yxiE T Belongs to the universal stress protein A family
HKKPOGGN_02563 1.6e-147 yxxF EG EamA-like transporter family
HKKPOGGN_02564 5.9e-202 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HKKPOGGN_02565 0.0 wapA M COG3209 Rhs family protein
HKKPOGGN_02566 1e-31
HKKPOGGN_02569 4.4e-16
HKKPOGGN_02570 1.3e-76
HKKPOGGN_02571 5.5e-14 S YxiJ-like protein
HKKPOGGN_02572 3e-20
HKKPOGGN_02574 1.8e-81 yxiI S Protein of unknown function (DUF2716)
HKKPOGGN_02575 1.7e-60 S SMI1-KNR4 cell-wall
HKKPOGGN_02578 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HKKPOGGN_02579 5.1e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
HKKPOGGN_02580 2.8e-142 exoK GH16 M licheninase activity
HKKPOGGN_02581 4e-221 citH C Citrate transporter
HKKPOGGN_02582 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKPOGGN_02583 1.4e-50 yxiS
HKKPOGGN_02584 4.3e-73 T Domain of unknown function (DUF4163)
HKKPOGGN_02585 2.5e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKPOGGN_02586 5.1e-159 rlmA 2.1.1.187 Q Methyltransferase domain
HKKPOGGN_02587 4.3e-219 yxjG 2.1.1.14 E Methionine synthase
HKKPOGGN_02588 2e-85 yxjI S LURP-one-related
HKKPOGGN_02591 9.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKKPOGGN_02592 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKKPOGGN_02593 1.9e-86 yxkC S Domain of unknown function (DUF4352)
HKKPOGGN_02594 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKKPOGGN_02595 4.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
HKKPOGGN_02596 1.6e-205 msmK P Belongs to the ABC transporter superfamily
HKKPOGGN_02597 3.9e-156 yxkH G Polysaccharide deacetylase
HKKPOGGN_02598 7.7e-215 cimH C COG3493 Na citrate symporter
HKKPOGGN_02599 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
HKKPOGGN_02600 4.6e-188 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HKKPOGGN_02601 0.0 cydD V ATP-binding
HKKPOGGN_02602 2.5e-290 cydD V ATP-binding protein
HKKPOGGN_02603 1.1e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKKPOGGN_02604 3.6e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HKKPOGGN_02605 4.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKKPOGGN_02606 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKPOGGN_02607 1.1e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HKKPOGGN_02608 5.3e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKKPOGGN_02609 3.7e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HKKPOGGN_02610 3.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKPOGGN_02611 5e-227 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKPOGGN_02612 3.8e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKPOGGN_02613 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKPOGGN_02614 3.2e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKKPOGGN_02615 2.2e-57 arsR K transcriptional
HKKPOGGN_02616 3e-167 cbrA3 P Periplasmic binding protein
HKKPOGGN_02617 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_02618 9.5e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_02619 2.9e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKKPOGGN_02621 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HKKPOGGN_02622 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HKKPOGGN_02623 4.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKPOGGN_02624 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKPOGGN_02625 3.3e-250 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKKPOGGN_02626 2.9e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKKPOGGN_02627 1.2e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKKPOGGN_02628 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_02629 1.1e-228 dltB M membrane protein involved in D-alanine export
HKKPOGGN_02630 1.2e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_02631 3e-11 S D-Ala-teichoic acid biosynthesis protein
HKKPOGGN_02632 3.8e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HKKPOGGN_02633 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
HKKPOGGN_02634 4.3e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKKPOGGN_02635 1.2e-48 ywaE K Transcriptional regulator
HKKPOGGN_02636 4.4e-163 gspA M General stress
HKKPOGGN_02637 2.6e-263 epr 3.4.21.62 O Belongs to the peptidase S8 family
HKKPOGGN_02638 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKPOGGN_02639 7.6e-67 ywbC 4.4.1.5 E glyoxalase
HKKPOGGN_02640 3e-223 ywbD 2.1.1.191 J Methyltransferase
HKKPOGGN_02641 1.2e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
HKKPOGGN_02642 1.4e-141 mta K transcriptional
HKKPOGGN_02643 3.9e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HKKPOGGN_02644 5.8e-110 ywbG M effector of murein hydrolase
HKKPOGGN_02645 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HKKPOGGN_02646 8.2e-152 ywbI K Transcriptional regulator
HKKPOGGN_02647 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKKPOGGN_02648 9.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKKPOGGN_02649 2e-241 ywbN P Dyp-type peroxidase family protein
HKKPOGGN_02650 1.2e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKKPOGGN_02651 1.2e-131 S Streptomycin biosynthesis protein StrF
HKKPOGGN_02652 3.1e-127 H Methionine biosynthesis protein MetW
HKKPOGGN_02654 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
HKKPOGGN_02655 1.7e-61 gtcA S GtrA-like protein
HKKPOGGN_02656 1.6e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKKPOGGN_02657 6.6e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKKPOGGN_02658 8.4e-27 ywzA S membrane
HKKPOGGN_02659 1.4e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HKKPOGGN_02660 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKKPOGGN_02661 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKKPOGGN_02662 6.4e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKKPOGGN_02663 3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HKKPOGGN_02664 3.1e-75 ysnE K acetyltransferase
HKKPOGGN_02665 9.8e-214 rodA D Belongs to the SEDS family
HKKPOGGN_02666 1.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKKPOGGN_02667 6.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_02668 2e-219 vpr O Belongs to the peptidase S8 family
HKKPOGGN_02669 5.5e-217 vpr O Belongs to the peptidase S8 family
HKKPOGGN_02671 1.3e-151 sacT K transcriptional antiterminator
HKKPOGGN_02672 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKPOGGN_02673 1e-281 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HKKPOGGN_02674 9.7e-20 ywdA
HKKPOGGN_02675 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKKPOGGN_02676 3.1e-56 pex K Transcriptional regulator PadR-like family
HKKPOGGN_02677 1.3e-87 ywdD
HKKPOGGN_02679 1.4e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
HKKPOGGN_02680 7.1e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKKPOGGN_02681 1.8e-40 ywdI S Family of unknown function (DUF5327)
HKKPOGGN_02682 1.7e-230 ywdJ F Xanthine uracil
HKKPOGGN_02683 4.2e-46 ywdK S small membrane protein
HKKPOGGN_02684 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HKKPOGGN_02685 1e-142 spsA M Spore Coat
HKKPOGGN_02686 3.1e-275 spsB M Capsule polysaccharide biosynthesis protein
HKKPOGGN_02687 3.7e-221 spsC E Belongs to the DegT DnrJ EryC1 family
HKKPOGGN_02688 6.6e-159 spsD 2.3.1.210 K Spore Coat
HKKPOGGN_02689 9.9e-216 spsE 2.5.1.56 M acid synthase
HKKPOGGN_02690 2.2e-134 spsF M Spore Coat
HKKPOGGN_02691 3.4e-183 spsG M Spore Coat
HKKPOGGN_02692 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKKPOGGN_02693 6.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKKPOGGN_02694 1.4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKKPOGGN_02695 3.5e-87 spsL 5.1.3.13 M Spore Coat
HKKPOGGN_02696 1.3e-171 bcrA5 V ABC transporter, ATP-binding protein
HKKPOGGN_02697 1.4e-119 S ABC-2 family transporter protein
HKKPOGGN_02698 7.3e-35 S Putative adhesin
HKKPOGGN_02699 5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_02700 6.6e-157 T PhoQ Sensor
HKKPOGGN_02701 4.3e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKPOGGN_02702 1.1e-294 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKKPOGGN_02703 0.0 rocB E arginine degradation protein
HKKPOGGN_02704 8.3e-260 lysP E amino acid
HKKPOGGN_02705 5.3e-207 tcaB EGP Major facilitator Superfamily
HKKPOGGN_02706 2.5e-220 ywfA EGP Major facilitator Superfamily
HKKPOGGN_02707 2.8e-111 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HKKPOGGN_02708 7.6e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HKKPOGGN_02709 3.9e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_02710 2.8e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HKKPOGGN_02711 4.7e-208 bacE EGP Major facilitator Superfamily
HKKPOGGN_02712 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
HKKPOGGN_02713 2.7e-138 IQ Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_02714 1.1e-146 ywfI C May function as heme-dependent peroxidase
HKKPOGGN_02715 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HKKPOGGN_02716 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
HKKPOGGN_02717 6.6e-162 cysL K Transcriptional regulator
HKKPOGGN_02718 1.1e-158 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HKKPOGGN_02720 4.4e-177
HKKPOGGN_02723 1.3e-168 yhcI S ABC transporter (permease)
HKKPOGGN_02724 6.5e-165 V ABC transporter, ATP-binding protein
HKKPOGGN_02725 6.8e-93 S membrane
HKKPOGGN_02726 8.2e-51 padR K PadR family transcriptional regulator
HKKPOGGN_02727 2.5e-109 rsfA_1
HKKPOGGN_02728 6.9e-36 ywzC S Belongs to the UPF0741 family
HKKPOGGN_02729 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HKKPOGGN_02730 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
HKKPOGGN_02731 3.5e-247 yhdG_1 E C-terminus of AA_permease
HKKPOGGN_02732 8e-70 ywhA K Transcriptional regulator
HKKPOGGN_02733 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HKKPOGGN_02734 1.2e-117 ywhC S Peptidase family M50
HKKPOGGN_02735 4e-95 ywhD S YwhD family
HKKPOGGN_02736 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKKPOGGN_02737 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKKPOGGN_02738 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
HKKPOGGN_02741 3.1e-76 CP Membrane
HKKPOGGN_02743 2e-28 S Domain of unknown function (DUF4177)
HKKPOGGN_02744 5e-33
HKKPOGGN_02745 9.7e-29 ydcG K sequence-specific DNA binding
HKKPOGGN_02747 1.4e-76 S aspartate phosphatase
HKKPOGGN_02748 3.5e-207 ywhK CO amine dehydrogenase activity
HKKPOGGN_02749 1.5e-226 ywhL CO amine dehydrogenase activity
HKKPOGGN_02751 8.6e-43 ywiB S protein conserved in bacteria
HKKPOGGN_02752 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKKPOGGN_02753 3.2e-212 narK P COG2223 Nitrate nitrite transporter
HKKPOGGN_02754 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HKKPOGGN_02755 1e-136 ywiC S YwiC-like protein
HKKPOGGN_02756 1.3e-84 arfM T cyclic nucleotide binding
HKKPOGGN_02757 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKPOGGN_02758 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
HKKPOGGN_02759 1.3e-96 narJ 1.7.5.1 C nitrate reductase
HKKPOGGN_02760 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HKKPOGGN_02761 3e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKKPOGGN_02762 2.9e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKKPOGGN_02763 0.0 ywjA V ABC transporter
HKKPOGGN_02764 4.2e-43 ywjC
HKKPOGGN_02765 3.7e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HKKPOGGN_02766 7.1e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKKPOGGN_02767 0.0 fadF C COG0247 Fe-S oxidoreductase
HKKPOGGN_02768 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKKPOGGN_02769 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKKPOGGN_02770 6.4e-93 ywjG S Domain of unknown function (DUF2529)
HKKPOGGN_02771 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HKKPOGGN_02772 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HKKPOGGN_02773 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKKPOGGN_02774 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKKPOGGN_02775 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HKKPOGGN_02776 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKKPOGGN_02777 1.1e-32 rpmE J Binds the 23S rRNA
HKKPOGGN_02778 1.4e-104 tdk 2.7.1.21 F thymidine kinase
HKKPOGGN_02779 0.0 sfcA 1.1.1.38 C malic enzyme
HKKPOGGN_02780 3.7e-155 ywkB S Membrane transport protein
HKKPOGGN_02781 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HKKPOGGN_02782 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKPOGGN_02783 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKKPOGGN_02784 4.7e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKKPOGGN_02786 8.8e-60 ywlA S Uncharacterised protein family (UPF0715)
HKKPOGGN_02787 6.8e-119 spoIIR S stage II sporulation protein R
HKKPOGGN_02788 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HKKPOGGN_02789 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKKPOGGN_02790 1.3e-83 mntP P Probably functions as a manganese efflux pump
HKKPOGGN_02791 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKKPOGGN_02792 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HKKPOGGN_02793 5.9e-97 ywlG S Belongs to the UPF0340 family
HKKPOGGN_02794 2.5e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKKPOGGN_02795 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKKPOGGN_02796 6.2e-61 atpI S ATP synthase
HKKPOGGN_02797 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HKKPOGGN_02798 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKKPOGGN_02799 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKKPOGGN_02800 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKKPOGGN_02801 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKKPOGGN_02802 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKKPOGGN_02803 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKKPOGGN_02804 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKKPOGGN_02805 3.5e-90 ywmA
HKKPOGGN_02806 1.3e-32 ywzB S membrane
HKKPOGGN_02807 3.3e-135 ywmB S TATA-box binding
HKKPOGGN_02808 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKKPOGGN_02809 3.3e-189 spoIID D Stage II sporulation protein D
HKKPOGGN_02810 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HKKPOGGN_02811 5e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HKKPOGGN_02813 2.2e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HKKPOGGN_02814 2.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HKKPOGGN_02815 1.5e-94 S response regulator aspartate phosphatase
HKKPOGGN_02816 3.6e-82 ywmF S Peptidase M50
HKKPOGGN_02817 7.4e-10 csbD K CsbD-like
HKKPOGGN_02818 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HKKPOGGN_02819 7.2e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HKKPOGGN_02820 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKKPOGGN_02821 2.1e-67 ywnA K Transcriptional regulator
HKKPOGGN_02823 1.7e-119 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HKKPOGGN_02824 5.7e-54 ywnC S Family of unknown function (DUF5362)
HKKPOGGN_02825 1.4e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKKPOGGN_02826 4.2e-69 ywnF S Family of unknown function (DUF5392)
HKKPOGGN_02827 3.4e-10 ywnC S Family of unknown function (DUF5362)
HKKPOGGN_02828 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HKKPOGGN_02829 3.5e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HKKPOGGN_02830 1.1e-71 ywnJ S VanZ like family
HKKPOGGN_02831 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HKKPOGGN_02832 6.4e-210 ftsW D Belongs to the SEDS family
HKKPOGGN_02833 2e-58 nrgB K Belongs to the P(II) protein family
HKKPOGGN_02834 2.5e-228 amt P Ammonium transporter
HKKPOGGN_02835 6.3e-102 phzA Q Isochorismatase family
HKKPOGGN_02836 6.8e-243 ywoD EGP Major facilitator superfamily
HKKPOGGN_02837 1.3e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HKKPOGGN_02838 1.1e-212 ywoG EGP Major facilitator Superfamily
HKKPOGGN_02839 8.5e-72 ywoH K transcriptional
HKKPOGGN_02840 1.8e-44 spoIIID K Stage III sporulation protein D
HKKPOGGN_02841 2.7e-180 mbl D Rod shape-determining protein
HKKPOGGN_02842 3.2e-128 flhO N flagellar basal body
HKKPOGGN_02843 4.5e-141 flhP N flagellar basal body
HKKPOGGN_02844 1.9e-200 S aspartate phosphatase
HKKPOGGN_02845 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKKPOGGN_02846 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKKPOGGN_02847 1.5e-68 ywpF S YwpF-like protein
HKKPOGGN_02848 4e-62 ywpG
HKKPOGGN_02849 1.3e-57 ssbB L Single-stranded DNA-binding protein
HKKPOGGN_02850 1.7e-137 glcR K DeoR C terminal sensor domain
HKKPOGGN_02851 1.1e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HKKPOGGN_02852 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKKPOGGN_02853 4.6e-307 ywqB S SWIM zinc finger
HKKPOGGN_02854 1.3e-14
HKKPOGGN_02855 5.2e-112 ywqC M biosynthesis protein
HKKPOGGN_02856 4.3e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HKKPOGGN_02857 7.1e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HKKPOGGN_02858 2.2e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKPOGGN_02859 5.1e-150 ywqG S Domain of unknown function (DUF1963)
HKKPOGGN_02861 1.9e-21 S Domain of unknown function (DUF5082)
HKKPOGGN_02862 4.3e-37 ywqI S Family of unknown function (DUF5344)
HKKPOGGN_02863 3.5e-259 ywqJ S Pre-toxin TG
HKKPOGGN_02864 3.5e-82 S Protein of unknown function (DUF2004)
HKKPOGGN_02865 1.8e-72 S SMI1 / KNR4 family
HKKPOGGN_02866 1e-68
HKKPOGGN_02867 1.2e-134 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HKKPOGGN_02868 6.9e-156 K Transcriptional regulator
HKKPOGGN_02869 1.4e-93 ywqN S NAD(P)H-dependent
HKKPOGGN_02871 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
HKKPOGGN_02872 4.6e-103 ywrB P Chromate transporter
HKKPOGGN_02873 1.1e-83 ywrC K Transcriptional regulator
HKKPOGGN_02874 4.7e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKKPOGGN_02875 6.1e-07 S Domain of unknown function (DUF4181)
HKKPOGGN_02876 3.7e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKKPOGGN_02877 1.1e-211 cotH M Spore Coat
HKKPOGGN_02878 1.9e-129 cotB
HKKPOGGN_02879 1.3e-125 ywrJ
HKKPOGGN_02880 5.2e-240 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKKPOGGN_02881 9e-167 alsR K LysR substrate binding domain
HKKPOGGN_02882 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKKPOGGN_02883 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HKKPOGGN_02884 1.4e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HKKPOGGN_02885 3.4e-89 batE T Sh3 type 3 domain protein
HKKPOGGN_02886 4.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HKKPOGGN_02887 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
HKKPOGGN_02888 7.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HKKPOGGN_02889 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKKPOGGN_02890 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKKPOGGN_02891 1.9e-178 rbsR K transcriptional
HKKPOGGN_02892 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
HKKPOGGN_02893 2.2e-191 gerKB E Spore germination protein
HKKPOGGN_02894 7.7e-184 gerKA EG Spore germination protein
HKKPOGGN_02895 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HKKPOGGN_02896 2.3e-70 pgsC S biosynthesis protein
HKKPOGGN_02897 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HKKPOGGN_02898 1.3e-20 ywtC
HKKPOGGN_02899 2.7e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKKPOGGN_02900 2.6e-36 yttA 2.7.13.3 S Pfam Transposase IS66
HKKPOGGN_02901 6.5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HKKPOGGN_02902 1.9e-178 ywtF K Transcriptional regulator
HKKPOGGN_02903 3.7e-249 ywtG EGP Major facilitator Superfamily
HKKPOGGN_02904 6.4e-265 GT2,GT4 J Glycosyl transferase family 2
HKKPOGGN_02905 1.2e-213 gerAC S Spore germination protein
HKKPOGGN_02906 1.7e-199 gerBB E Spore germination protein
HKKPOGGN_02907 1e-265 gerBA EG Spore germination protein
HKKPOGGN_02908 3.7e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HKKPOGGN_02909 5.7e-230 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKKPOGGN_02910 2.2e-218 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKKPOGGN_02911 5.9e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKKPOGGN_02912 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HKKPOGGN_02913 1.7e-279 M Glycosyltransferase like family 2
HKKPOGGN_02914 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKKPOGGN_02915 2.8e-151 tagG GM Transport permease protein
HKKPOGGN_02916 1.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKKPOGGN_02917 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKPOGGN_02918 2.4e-209 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKKPOGGN_02919 6.5e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HKKPOGGN_02920 5.9e-49
HKKPOGGN_02921 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HKKPOGGN_02922 1.3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKPOGGN_02923 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKKPOGGN_02924 2.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_02925 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HKKPOGGN_02926 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKPOGGN_02927 5.5e-256 tuaE M Teichuronic acid biosynthesis protein
HKKPOGGN_02928 3.3e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HKKPOGGN_02929 1.7e-142 tuaG GT2 M Glycosyltransferase like family 2
HKKPOGGN_02930 1e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HKKPOGGN_02931 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HKKPOGGN_02932 4.1e-172 yvhJ K Transcriptional regulator
HKKPOGGN_02933 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HKKPOGGN_02934 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKKPOGGN_02935 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_02936 1.9e-158 degV S protein conserved in bacteria
HKKPOGGN_02937 1.6e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKKPOGGN_02938 1.7e-42 comFB S Late competence development protein ComFB
HKKPOGGN_02939 1.2e-77 comFC S Phosphoribosyl transferase domain
HKKPOGGN_02940 4.1e-74 yvyF S flagellar protein
HKKPOGGN_02941 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HKKPOGGN_02942 1.7e-79 flgN NOU FlgN protein
HKKPOGGN_02943 5.3e-273 flgK N flagellar hook-associated protein
HKKPOGGN_02944 6.1e-163 flgL N Belongs to the bacterial flagellin family
HKKPOGGN_02945 1.4e-80 yviE
HKKPOGGN_02946 3.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HKKPOGGN_02947 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HKKPOGGN_02948 3.9e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKKPOGGN_02949 1.2e-259 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HKKPOGGN_02950 8.8e-66 fliS N flagellar protein FliS
HKKPOGGN_02951 9.1e-11 fliT S bacterial-type flagellum organization
HKKPOGGN_02952 6.8e-68
HKKPOGGN_02953 1.4e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKKPOGGN_02954 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKKPOGGN_02955 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKKPOGGN_02956 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_02957 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
HKKPOGGN_02958 1e-122 ftsE D cell division ATP-binding protein FtsE
HKKPOGGN_02959 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKKPOGGN_02960 5e-225 ywoF P Right handed beta helix region
HKKPOGGN_02961 3.2e-256 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HKKPOGGN_02962 1.5e-55 swrA S Swarming motility protein
HKKPOGGN_02963 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKPOGGN_02965 4.1e-21 E Saccharopine dehydrogenase
HKKPOGGN_02967 5.6e-176 S Psort location CytoplasmicMembrane, score
HKKPOGGN_02969 2.4e-26 bacT Q Thioesterase domain
HKKPOGGN_02970 1.5e-226 yvkA EGP Major facilitator Superfamily
HKKPOGGN_02971 2.4e-110 yvkB K Transcriptional regulator
HKKPOGGN_02972 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HKKPOGGN_02973 7.6e-33 csbA S protein conserved in bacteria
HKKPOGGN_02974 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKKPOGGN_02975 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKKPOGGN_02976 2.2e-32 yvkN
HKKPOGGN_02977 6.1e-49 yvlA
HKKPOGGN_02978 3.2e-166 yvlB S Putative adhesin
HKKPOGGN_02979 9.6e-26 pspB KT PspC domain
HKKPOGGN_02980 3.9e-41 yvlD S Membrane
HKKPOGGN_02981 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HKKPOGGN_02982 4.7e-105 yxaF K Transcriptional regulator
HKKPOGGN_02983 6.8e-133 yvoA K transcriptional
HKKPOGGN_02984 1.2e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKKPOGGN_02985 5.7e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKKPOGGN_02986 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKKPOGGN_02987 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKKPOGGN_02988 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HKKPOGGN_02989 5.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HKKPOGGN_02990 3.1e-138 yvpB NU protein conserved in bacteria
HKKPOGGN_02991 1.4e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKKPOGGN_02992 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKKPOGGN_02993 8.5e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKKPOGGN_02994 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKKPOGGN_02995 4.7e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKKPOGGN_02996 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKKPOGGN_02997 5.2e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKKPOGGN_02998 1.2e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HKKPOGGN_02999 0.0 msbA2 3.6.3.44 V ABC transporter
HKKPOGGN_03000 3.3e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_03001 3.2e-192 sasA T Histidine kinase
HKKPOGGN_03002 7.9e-274 S COG0457 FOG TPR repeat
HKKPOGGN_03003 5.6e-123 usp CBM50 M protein conserved in bacteria
HKKPOGGN_03004 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKKPOGGN_03005 1.9e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKKPOGGN_03006 3.3e-166 rapZ S Displays ATPase and GTPase activities
HKKPOGGN_03007 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKKPOGGN_03008 3.1e-170 whiA K May be required for sporulation
HKKPOGGN_03009 4.7e-36 crh G Phosphocarrier protein Chr
HKKPOGGN_03010 3.7e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HKKPOGGN_03011 4.6e-79 M Ribonuclease
HKKPOGGN_03012 4.7e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKPOGGN_03013 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKKPOGGN_03014 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKKPOGGN_03015 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKKPOGGN_03016 7.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HKKPOGGN_03017 1.7e-249 EGP Sugar (and other) transporter
HKKPOGGN_03018 3.5e-213 yraM S PrpF protein
HKKPOGGN_03019 6.7e-164 yraN K Transcriptional regulator
HKKPOGGN_03020 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKKPOGGN_03021 1.7e-184 scrR K transcriptional
HKKPOGGN_03022 4.7e-219 rafB P LacY proton/sugar symporter
HKKPOGGN_03023 6.7e-297 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HKKPOGGN_03025 3.4e-33
HKKPOGGN_03026 1.7e-241 I Pfam Lipase (class 3)
HKKPOGGN_03027 1e-15 S Protein of unknown function (DUF1433)
HKKPOGGN_03029 1.2e-24 S Protein of unknown function (DUF1433)
HKKPOGGN_03030 1.3e-15 S Protein of unknown function (DUF1433)
HKKPOGGN_03031 5.5e-94 padC Q Phenolic acid decarboxylase
HKKPOGGN_03032 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKPOGGN_03033 4.4e-112 yyaS S Membrane
HKKPOGGN_03034 2.6e-97 ywjB H RibD C-terminal domain
HKKPOGGN_03036 4.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HKKPOGGN_03037 1.9e-77 slr K transcriptional
HKKPOGGN_03038 5.4e-119 ywqC M biosynthesis protein
HKKPOGGN_03039 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HKKPOGGN_03040 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HKKPOGGN_03041 9.7e-219 epsD GT4 M Glycosyl transferase 4-like
HKKPOGGN_03042 3.4e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKPOGGN_03043 7.2e-214 epsF GT4 M Glycosyl transferases group 1
HKKPOGGN_03044 3.5e-205 epsG S EpsG family
HKKPOGGN_03045 2.4e-192 epsH GT2 S Glycosyltransferase like family 2
HKKPOGGN_03046 9.8e-205 epsI GM pyruvyl transferase
HKKPOGGN_03047 1e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKPOGGN_03048 2.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_03049 1.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKKPOGGN_03050 1.1e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HKKPOGGN_03051 1.8e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKKPOGGN_03052 1.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HKKPOGGN_03053 2.7e-32 yvfG S YvfG protein
HKKPOGGN_03054 1e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HKKPOGGN_03055 2.2e-304 yvfH C L-lactate permease
HKKPOGGN_03056 3.3e-119 yvfI K COG2186 Transcriptional regulators
HKKPOGGN_03057 1e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKPOGGN_03058 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKKPOGGN_03059 3.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HKKPOGGN_03060 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKKPOGGN_03061 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
HKKPOGGN_03062 6e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HKKPOGGN_03063 7.7e-152 ybbH_1 K RpiR family transcriptional regulator
HKKPOGGN_03065 5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HKKPOGGN_03066 2.9e-157 yvbV EG EamA-like transporter family
HKKPOGGN_03067 2.4e-156 yvbU K Transcriptional regulator
HKKPOGGN_03069 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_03070 1.4e-203 araR K transcriptional
HKKPOGGN_03071 7.4e-253 araE EGP Major facilitator Superfamily
HKKPOGGN_03073 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKKPOGGN_03074 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKKPOGGN_03075 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKKPOGGN_03076 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKKPOGGN_03077 1.1e-297 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HKKPOGGN_03078 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKKPOGGN_03079 8.9e-237 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HKKPOGGN_03080 1.4e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKPOGGN_03081 4e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKKPOGGN_03082 8e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
HKKPOGGN_03083 1.3e-232 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HKKPOGGN_03084 3.5e-147 M Protein involved in cellulose biosynthesis
HKKPOGGN_03085 9.6e-143 C WbqC-like protein family
HKKPOGGN_03086 1.2e-126 S GlcNAc-PI de-N-acetylase
HKKPOGGN_03087 9.4e-180
HKKPOGGN_03088 5.6e-212 EGP Major facilitator Superfamily
HKKPOGGN_03089 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
HKKPOGGN_03090 0.0 tcaA S response to antibiotic
HKKPOGGN_03091 8.4e-120 exoY M Membrane
HKKPOGGN_03092 5.2e-105 yvbG U UPF0056 membrane protein
HKKPOGGN_03093 1.6e-97 yvbF K Belongs to the GbsR family
HKKPOGGN_03094 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKKPOGGN_03095 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKPOGGN_03096 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKKPOGGN_03097 3.7e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKPOGGN_03098 2.8e-75 yvbF K Belongs to the GbsR family
HKKPOGGN_03099 2.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKKPOGGN_03100 3.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKPOGGN_03101 1.9e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKKPOGGN_03102 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKPOGGN_03103 6e-126 mutF V ABC transporter, ATP-binding protein
HKKPOGGN_03104 4.6e-121 spaE S ABC-2 family transporter protein
HKKPOGGN_03105 2e-135 mutG S ABC-2 family transporter protein
HKKPOGGN_03106 2e-123 K Transcriptional regulatory protein, C terminal
HKKPOGGN_03107 2.2e-257 T His Kinase A (phosphoacceptor) domain
HKKPOGGN_03108 4.4e-52 yodB K transcriptional
HKKPOGGN_03109 3e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HKKPOGGN_03110 1e-69 K transcriptional
HKKPOGGN_03111 6e-35 yvzC K Transcriptional
HKKPOGGN_03112 4.8e-24 secG U Preprotein translocase subunit SecG
HKKPOGGN_03113 7.4e-143 est 3.1.1.1 S Carboxylesterase
HKKPOGGN_03114 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKKPOGGN_03115 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HKKPOGGN_03117 6.7e-50 yrdF K ribonuclease inhibitor
HKKPOGGN_03118 7.7e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_03119 5.2e-159 ytlI K LysR substrate binding domain
HKKPOGGN_03120 3e-101 ytmI K Acetyltransferase (GNAT) domain
HKKPOGGN_03121 5.1e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
HKKPOGGN_03122 7.1e-147 tcyK M Bacterial periplasmic substrate-binding proteins
HKKPOGGN_03123 4.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HKKPOGGN_03124 4.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HKKPOGGN_03125 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKPOGGN_03126 3.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_03127 1.6e-45 ytnI O COG0695 Glutaredoxin and related proteins
HKKPOGGN_03128 2.7e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_03129 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKKPOGGN_03130 9.9e-194 yvaA 1.1.1.371 S Oxidoreductase
HKKPOGGN_03131 3.7e-48 csoR S transcriptional
HKKPOGGN_03132 9.9e-29 copZ P Heavy-metal-associated domain
HKKPOGGN_03133 0.0 copA 3.6.3.54 P P-type ATPase
HKKPOGGN_03134 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKKPOGGN_03135 7.5e-102 bdbD O Thioredoxin
HKKPOGGN_03136 6e-73 bdbC O Required for disulfide bond formation in some proteins
HKKPOGGN_03137 1.2e-141 S Metallo-peptidase family M12
HKKPOGGN_03138 3.1e-99 yvgT S membrane
HKKPOGGN_03139 0.0 helD 3.6.4.12 L DNA helicase
HKKPOGGN_03140 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKKPOGGN_03141 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HKKPOGGN_03142 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HKKPOGGN_03143 1.1e-86 yvgO
HKKPOGGN_03144 5e-156 yvgN S reductase
HKKPOGGN_03145 6.8e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
HKKPOGGN_03146 1.4e-193 yfiM V ABC-2 type transporter
HKKPOGGN_03147 4.7e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HKKPOGGN_03148 2.1e-178 T Histidine kinase
HKKPOGGN_03149 1.3e-114 yfiK K Regulator
HKKPOGGN_03150 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
HKKPOGGN_03151 4.1e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HKKPOGGN_03152 5.9e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HKKPOGGN_03153 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKPOGGN_03154 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HKKPOGGN_03155 3.6e-14 S Small spore protein J (Spore_SspJ)
HKKPOGGN_03156 1.3e-236 yvsH E Arginine ornithine antiporter
HKKPOGGN_03157 2.2e-176 fhuD P ABC transporter
HKKPOGGN_03158 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_03159 4.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_03160 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
HKKPOGGN_03161 9.3e-66 yvrL S Regulatory protein YrvL
HKKPOGGN_03162 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
HKKPOGGN_03163 1.2e-15 S YvrJ protein family
HKKPOGGN_03164 1.3e-102 yvrI K RNA polymerase
HKKPOGGN_03165 1.1e-36
HKKPOGGN_03166 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_03167 0.0 T PhoQ Sensor
HKKPOGGN_03168 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
HKKPOGGN_03169 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_03170 1.6e-166 yvrC P ABC transporter substrate-binding protein
HKKPOGGN_03171 1.5e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_03172 2e-222 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKKPOGGN_03173 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
HKKPOGGN_03174 1.7e-227 yvqJ EGP Major facilitator Superfamily
HKKPOGGN_03175 3.3e-46 liaI S membrane
HKKPOGGN_03176 4.4e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HKKPOGGN_03177 1.6e-112 liaG S Putative adhesin
HKKPOGGN_03178 2.8e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HKKPOGGN_03179 2.3e-193 vraS 2.7.13.3 T Histidine kinase
HKKPOGGN_03180 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_03181 8.6e-204 gerAC S Spore germination B3/ GerAC like, C-terminal
HKKPOGGN_03182 7.2e-187 gerAB E Spore germination protein
HKKPOGGN_03183 6e-258 gerAA EG Spore germination protein
HKKPOGGN_03184 6.6e-24 S Protein of unknown function (DUF3970)
HKKPOGGN_03185 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKKPOGGN_03186 1e-157 yuxN K Transcriptional regulator
HKKPOGGN_03187 1.3e-23
HKKPOGGN_03188 6.7e-251 cssS 2.7.13.3 T PhoQ Sensor
HKKPOGGN_03189 7.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_03190 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKPOGGN_03191 1.4e-78 dps P Belongs to the Dps family
HKKPOGGN_03192 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_03193 0.0 pepF2 E COG1164 Oligoendopeptidase F
HKKPOGGN_03194 1.2e-44 S YusW-like protein
HKKPOGGN_03195 3.1e-150 yusV 3.6.3.34 HP ABC transporter
HKKPOGGN_03196 3.3e-39 yusU S Protein of unknown function (DUF2573)
HKKPOGGN_03197 2.1e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKKPOGGN_03198 5.5e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HKKPOGGN_03199 3.3e-158 ywbI2 K Transcriptional regulator
HKKPOGGN_03200 8.1e-288 yusP P Major facilitator superfamily
HKKPOGGN_03201 2.8e-68 yusO K Iron dependent repressor, N-terminal DNA binding domain
HKKPOGGN_03202 7.1e-53 yusN M Coat F domain
HKKPOGGN_03203 3.9e-43
HKKPOGGN_03204 1.9e-164 fadM E Proline dehydrogenase
HKKPOGGN_03206 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HKKPOGGN_03207 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HKKPOGGN_03208 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HKKPOGGN_03209 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HKKPOGGN_03210 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HKKPOGGN_03211 3.7e-40 yusG S Protein of unknown function (DUF2553)
HKKPOGGN_03212 8.3e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HKKPOGGN_03213 1.6e-54 yusE CO Thioredoxin
HKKPOGGN_03214 5e-57 yusD S SCP-2 sterol transfer family
HKKPOGGN_03215 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKKPOGGN_03216 2e-94 metI P COG2011 ABC-type metal ion transport system, permease component
HKKPOGGN_03217 3.9e-145 metQ P Belongs to the NlpA lipoprotein family
HKKPOGGN_03218 2.2e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKKPOGGN_03219 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKKPOGGN_03220 7e-245 sufD O assembly protein SufD
HKKPOGGN_03221 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKKPOGGN_03222 1.1e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HKKPOGGN_03223 3e-270 sufB O FeS cluster assembly
HKKPOGGN_03224 3.9e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HKKPOGGN_03225 2.5e-80 yncE S Protein of unknown function (DUF2691)
HKKPOGGN_03226 7.5e-129 Q ubiE/COQ5 methyltransferase family
HKKPOGGN_03227 6.8e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HKKPOGGN_03228 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HKKPOGGN_03230 2.3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HKKPOGGN_03231 1.2e-244 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HKKPOGGN_03232 3.4e-158 yurN G Binding-protein-dependent transport system inner membrane component
HKKPOGGN_03233 5.9e-163 yurM P COG0395 ABC-type sugar transport system, permease component
HKKPOGGN_03234 6.3e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HKKPOGGN_03235 3.6e-134 yurK K UTRA
HKKPOGGN_03236 9.2e-206 msmX P Belongs to the ABC transporter superfamily
HKKPOGGN_03237 6e-168 bsn L Ribonuclease
HKKPOGGN_03238 3.1e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HKKPOGGN_03239 3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HKKPOGGN_03240 3.8e-213 blt EGP Major facilitator Superfamily
HKKPOGGN_03241 1.7e-25
HKKPOGGN_03242 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HKKPOGGN_03243 5.5e-261 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HKKPOGGN_03244 9.8e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HKKPOGGN_03245 8.1e-170 yunF S Protein of unknown function DUF72
HKKPOGGN_03246 1.8e-145 yunE S membrane transporter protein
HKKPOGGN_03247 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKKPOGGN_03248 5.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
HKKPOGGN_03249 8.4e-195 lytH M Peptidase, M23
HKKPOGGN_03250 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKKPOGGN_03251 1.7e-47 yutD S protein conserved in bacteria
HKKPOGGN_03252 1.6e-73 yutE S Protein of unknown function DUF86
HKKPOGGN_03253 1.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKKPOGGN_03254 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKKPOGGN_03255 3.2e-197 yutH S Spore coat protein
HKKPOGGN_03256 3.5e-241 hom 1.1.1.3 E homoserine dehydrogenase
HKKPOGGN_03257 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HKKPOGGN_03258 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKKPOGGN_03259 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HKKPOGGN_03260 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HKKPOGGN_03261 1.7e-54 yuzD S protein conserved in bacteria
HKKPOGGN_03262 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HKKPOGGN_03263 2.4e-39 yuzB S Belongs to the UPF0349 family
HKKPOGGN_03264 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKPOGGN_03265 3.7e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKKPOGGN_03266 1.1e-62 erpA S Belongs to the HesB IscA family
HKKPOGGN_03267 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_03268 1e-15 K helix_turn_helix, mercury resistance
HKKPOGGN_03270 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HKKPOGGN_03272 1.8e-122 V ABC transporter
HKKPOGGN_03273 1.8e-71 CP Membrane
HKKPOGGN_03274 4.8e-29
HKKPOGGN_03275 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKKPOGGN_03277 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
HKKPOGGN_03278 2.5e-233 yumB 1.6.99.3 C NADH dehydrogenase
HKKPOGGN_03279 3.8e-27 yuiB S Putative membrane protein
HKKPOGGN_03280 1.2e-117 yuiC S protein conserved in bacteria
HKKPOGGN_03281 1.3e-76 yuiD S protein conserved in bacteria
HKKPOGGN_03282 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKKPOGGN_03283 1.1e-208 yuiF S antiporter
HKKPOGGN_03284 1.5e-101 bioY S Biotin biosynthesis protein
HKKPOGGN_03285 7.8e-119 yuiH S Oxidoreductase molybdopterin binding domain
HKKPOGGN_03286 6.8e-164 besA S Putative esterase
HKKPOGGN_03287 2.3e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKPOGGN_03288 1.3e-221 entC 5.4.4.2 HQ Isochorismate synthase
HKKPOGGN_03289 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HKKPOGGN_03290 7.2e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HKKPOGGN_03291 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_03292 1.3e-34 mbtH S MbtH-like protein
HKKPOGGN_03293 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
HKKPOGGN_03294 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HKKPOGGN_03295 1.8e-226 yukF QT Transcriptional regulator
HKKPOGGN_03296 3.3e-46 esxA S Belongs to the WXG100 family
HKKPOGGN_03297 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HKKPOGGN_03298 6.2e-206 essB S WXG100 protein secretion system (Wss), protein YukC
HKKPOGGN_03299 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HKKPOGGN_03300 0.0 esaA S type VII secretion protein EsaA
HKKPOGGN_03301 1.7e-76 yueC S Family of unknown function (DUF5383)
HKKPOGGN_03302 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_03303 3.7e-96 yueE S phosphohydrolase
HKKPOGGN_03304 2.1e-22 S Protein of unknown function (DUF2642)
HKKPOGGN_03305 5.6e-187 yueF S transporter activity
HKKPOGGN_03306 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HKKPOGGN_03307 2.8e-38 yueH S YueH-like protein
HKKPOGGN_03308 4.6e-67 yueI S Protein of unknown function (DUF1694)
HKKPOGGN_03309 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HKKPOGGN_03310 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKKPOGGN_03311 2e-230 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HKKPOGGN_03312 1.8e-51 yuzC
HKKPOGGN_03314 1.5e-97 comQ H Belongs to the FPP GGPP synthase family
HKKPOGGN_03316 8.1e-273 comP 2.7.13.3 T Histidine kinase
HKKPOGGN_03317 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_03318 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HKKPOGGN_03319 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HKKPOGGN_03320 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKPOGGN_03321 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKPOGGN_03322 3.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKPOGGN_03323 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKPOGGN_03324 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKPOGGN_03325 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKKPOGGN_03326 1.4e-12
HKKPOGGN_03327 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HKKPOGGN_03328 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HKKPOGGN_03329 7.5e-283 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HKKPOGGN_03330 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HKKPOGGN_03331 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HKKPOGGN_03332 4.4e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKPOGGN_03333 3.6e-73 yufK S Family of unknown function (DUF5366)
HKKPOGGN_03334 3.8e-72 yuxK S protein conserved in bacteria
HKKPOGGN_03335 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HKKPOGGN_03336 5.9e-185 yuxJ EGP Major facilitator Superfamily
HKKPOGGN_03337 4e-118 kapD L the KinA pathway to sporulation
HKKPOGGN_03338 4.9e-12 kapB G Kinase associated protein B
HKKPOGGN_03339 4.9e-227 T PhoQ Sensor
HKKPOGGN_03340 7.1e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKKPOGGN_03341 1.4e-40 yugE S Domain of unknown function (DUF1871)
HKKPOGGN_03342 1.2e-154 yugF I Hydrolase
HKKPOGGN_03343 2e-83 alaR K Transcriptional regulator
HKKPOGGN_03344 7.2e-209 yugH 2.6.1.1 E Aminotransferase
HKKPOGGN_03345 4.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HKKPOGGN_03346 1.8e-34 yuzA S Domain of unknown function (DUF378)
HKKPOGGN_03347 4.9e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HKKPOGGN_03348 7.4e-230 yugK C Dehydrogenase
HKKPOGGN_03349 4.2e-118 ycaC Q Isochorismatase family
HKKPOGGN_03350 1e-96 S NADPH-dependent FMN reductase
HKKPOGGN_03351 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
HKKPOGGN_03353 1.3e-72 yugN S YugN-like family
HKKPOGGN_03354 1.8e-181 yugO P COG1226 Kef-type K transport systems
HKKPOGGN_03355 1.1e-26 mstX S Membrane-integrating protein Mistic
HKKPOGGN_03356 3.8e-17
HKKPOGGN_03357 4.1e-116 yugP S Zn-dependent protease
HKKPOGGN_03358 1.1e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HKKPOGGN_03359 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HKKPOGGN_03360 8.1e-78 yugU S Uncharacterised protein family UPF0047
HKKPOGGN_03361 2.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HKKPOGGN_03362 4.8e-41
HKKPOGGN_03363 1.9e-138 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HKKPOGGN_03364 4e-220 mcpA NT chemotaxis protein
HKKPOGGN_03365 2.8e-237 mcpA NT chemotaxis protein
HKKPOGGN_03366 7.8e-224 mcpA NT chemotaxis protein
HKKPOGGN_03367 6.9e-236 mcpA NT chemotaxis protein
HKKPOGGN_03368 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HKKPOGGN_03369 6.7e-184 ygjR S Oxidoreductase
HKKPOGGN_03370 7.6e-195 yubA S transporter activity
HKKPOGGN_03371 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKKPOGGN_03373 3.2e-50 yjcN
HKKPOGGN_03374 5.3e-121 G Cupin
HKKPOGGN_03375 1.7e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKKPOGGN_03376 1.1e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKKPOGGN_03377 2.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
HKKPOGGN_03378 2.1e-94 yuaB
HKKPOGGN_03379 6e-97 yuaC K Belongs to the GbsR family
HKKPOGGN_03380 6.1e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HKKPOGGN_03381 3.5e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HKKPOGGN_03382 4.2e-109 yuaD S MOSC domain
HKKPOGGN_03383 7.6e-80 yuaE S DinB superfamily
HKKPOGGN_03384 2.5e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HKKPOGGN_03385 2e-179 yuaG 3.4.21.72 S protein conserved in bacteria
HKKPOGGN_03386 3.7e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
HKKPOGGN_03387 0.0 pksJ Q Polyketide synthase of type I
HKKPOGGN_03388 0.0 1.1.1.320 Q Polyketide synthase of type I
HKKPOGGN_03389 0.0 Q Polyketide synthase of type I
HKKPOGGN_03390 1.3e-87 pksJ Q Polyketide synthase of type I
HKKPOGGN_03393 2.7e-250 iolT EGP Major facilitator Superfamily
HKKPOGGN_03394 4e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
HKKPOGGN_03395 1e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HKKPOGGN_03396 3.2e-166 ydhU P Catalase
HKKPOGGN_03397 7.9e-296 yveA E amino acid
HKKPOGGN_03398 2e-103 yvdT K Transcriptional regulator
HKKPOGGN_03399 6.6e-51 ykkC P Small Multidrug Resistance protein
HKKPOGGN_03400 2.6e-49 sugE P Small Multidrug Resistance protein
HKKPOGGN_03401 7.4e-217 yeaN P COG2807 Cyanate permease
HKKPOGGN_03402 2.6e-118 K FCD
HKKPOGGN_03403 1.3e-133 ydhQ K UTRA
HKKPOGGN_03404 4.5e-195 pbuE EGP Major facilitator Superfamily
HKKPOGGN_03405 7.2e-98 ydhK M Protein of unknown function (DUF1541)
HKKPOGGN_03407 2.2e-262 pbpE V Beta-lactamase
HKKPOGGN_03410 1.1e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKKPOGGN_03411 8.1e-120 ydhC K FCD
HKKPOGGN_03412 2.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HKKPOGGN_03413 5.2e-106 S Alpha/beta hydrolase family
HKKPOGGN_03414 3.3e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HKKPOGGN_03415 8.1e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKKPOGGN_03416 1.7e-148 bltR K helix_turn_helix, mercury resistance
HKKPOGGN_03417 2.6e-82 bltD 2.3.1.57 K FR47-like protein
HKKPOGGN_03418 2.9e-123 ydhB S membrane transporter protein
HKKPOGGN_03419 3e-156 K Helix-turn-helix XRE-family like proteins
HKKPOGGN_03420 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKKPOGGN_03421 3.9e-210 tcaB EGP Major facilitator Superfamily
HKKPOGGN_03422 1e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HKKPOGGN_03423 3.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HKKPOGGN_03424 7.9e-99 ynaD J Acetyltransferase (GNAT) domain
HKKPOGGN_03425 2.1e-299 expZ S ABC transporter
HKKPOGGN_03426 1e-133 puuD S Peptidase C26
HKKPOGGN_03427 0.0 ydfJ S drug exporters of the RND superfamily
HKKPOGGN_03428 1.1e-107 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKPOGGN_03429 5.2e-205 ydfH 2.7.13.3 T Histidine kinase
HKKPOGGN_03430 5.8e-36 yraG
HKKPOGGN_03431 2.2e-63 yraF M Spore coat protein
HKKPOGGN_03432 5.5e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKKPOGGN_03433 2.4e-24 yraE
HKKPOGGN_03434 1.1e-47 yraD M Spore coat protein
HKKPOGGN_03435 1.4e-264 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKPOGGN_03436 4.1e-156 ydeK EG -transporter
HKKPOGGN_03437 6.4e-102 ydeS K Transcriptional regulator
HKKPOGGN_03438 4.9e-181 ydeR EGP Major facilitator Superfamily
HKKPOGGN_03440 7.1e-115 paiB K Transcriptional regulator
HKKPOGGN_03441 1.9e-264 K helix_turn_helix gluconate operon transcriptional repressor
HKKPOGGN_03442 2.2e-227 mleN_2 C antiporter
HKKPOGGN_03443 3.6e-67 yraB K helix_turn_helix, mercury resistance
HKKPOGGN_03444 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
HKKPOGGN_03445 9.5e-167 S Sodium Bile acid symporter family
HKKPOGGN_03446 4.1e-52 ydeH
HKKPOGGN_03447 7.6e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HKKPOGGN_03449 2.8e-148 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HKKPOGGN_03450 4.5e-86 ykkA S Protein of unknown function (DUF664)
HKKPOGGN_03451 1e-101 yrkC G Cupin domain
HKKPOGGN_03453 1.3e-201 trkA P Oxidoreductase
HKKPOGGN_03454 1.4e-167 czcD P COG1230 Co Zn Cd efflux system component
HKKPOGGN_03455 6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
HKKPOGGN_03458 5.4e-62 G Cupin domain
HKKPOGGN_03459 4.1e-78 S DinB superfamily
HKKPOGGN_03460 6.2e-182 S Patatin-like phospholipase
HKKPOGGN_03461 1.9e-234 ybfB G COG0477 Permeases of the major facilitator superfamily
HKKPOGGN_03462 4.3e-169 ybfA 3.4.15.5 K FR47-like protein
HKKPOGGN_03463 4.9e-51 K Transcriptional regulator PadR-like family
HKKPOGGN_03464 2e-103 S Protein of unknown function (DUF2812)
HKKPOGGN_03465 6e-123 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKKPOGGN_03466 1.2e-79 carD K Transcription factor
HKKPOGGN_03467 1.4e-30 cspL K Cold shock
HKKPOGGN_03468 2.2e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKKPOGGN_03469 4.6e-175 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKKPOGGN_03470 1.2e-111 C Enoyl-(Acyl carrier protein) reductase
HKKPOGGN_03471 9.6e-90 K Bacterial regulatory proteins, tetR family
HKKPOGGN_03473 4.9e-111 ywnB S NAD(P)H-binding
HKKPOGGN_03474 4.4e-74 ywnA K Transcriptional regulator
HKKPOGGN_03475 3.8e-65 yyaQ S YjbR
HKKPOGGN_03476 1.4e-74 maoC I N-terminal half of MaoC dehydratase
HKKPOGGN_03477 5.5e-71 S Domain of unknown function with cystatin-like fold (DUF4467)
HKKPOGGN_03478 2.6e-49 ohrR K Transcriptional regulator
HKKPOGGN_03479 1.3e-228 proP EGP Transporter
HKKPOGGN_03480 4.8e-96 ywrO S Flavodoxin-like fold
HKKPOGGN_03481 5.5e-08
HKKPOGGN_03489 1.1e-56 ydcK S Belongs to the SprT family
HKKPOGGN_03490 1.7e-14
HKKPOGGN_03491 0.0 yhgF K COG2183 Transcriptional accessory protein
HKKPOGGN_03492 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HKKPOGGN_03493 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKPOGGN_03494 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HKKPOGGN_03495 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HKKPOGGN_03496 1.7e-187 rsbU 3.1.3.3 KT phosphatase
HKKPOGGN_03497 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HKKPOGGN_03498 6.8e-57 rsbS T antagonist
HKKPOGGN_03499 6.1e-146 rsbR T Positive regulator of sigma-B
HKKPOGGN_03500 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKKPOGGN_03501 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HKKPOGGN_03502 3.4e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKKPOGGN_03503 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HKKPOGGN_03504 2.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKKPOGGN_03505 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HKKPOGGN_03506 9.1e-262 ydbT S Membrane
HKKPOGGN_03507 2.1e-82 ydbS S Bacterial PH domain
HKKPOGGN_03508 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKKPOGGN_03509 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKKPOGGN_03510 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKKPOGGN_03511 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKKPOGGN_03512 4.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKPOGGN_03513 5.8e-09 S Fur-regulated basic protein A
HKKPOGGN_03514 1.5e-10 S Fur-regulated basic protein B
HKKPOGGN_03515 3.5e-205 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HKKPOGGN_03516 1.1e-50 ydbL
HKKPOGGN_03517 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKKPOGGN_03518 5e-173 ydbJ V ABC transporter, ATP-binding protein
HKKPOGGN_03519 3.2e-160 ydbI S AI-2E family transporter
HKKPOGGN_03520 1.9e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKPOGGN_03521 1.1e-118 dctR T COG4565 Response regulator of citrate malate metabolism
HKKPOGGN_03522 7.9e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKPOGGN_03523 9.3e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HKKPOGGN_03524 1.6e-154 ydbD P Catalase
HKKPOGGN_03525 3.8e-28 ydbC S Domain of unknown function (DUF4937
HKKPOGGN_03526 7.5e-58 ydbB G Cupin domain
HKKPOGGN_03528 1.5e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HKKPOGGN_03529 7e-54 yvaE P Small Multidrug Resistance protein
HKKPOGGN_03530 5.4e-71 yvaD S Family of unknown function (DUF5360)
HKKPOGGN_03531 6.5e-34 ydaT
HKKPOGGN_03533 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HKKPOGGN_03534 2.1e-39
HKKPOGGN_03535 3.7e-97
HKKPOGGN_03536 6.3e-78
HKKPOGGN_03538 3.6e-11
HKKPOGGN_03540 3.8e-207 S Histidine kinase
HKKPOGGN_03541 1.3e-69
HKKPOGGN_03542 1.8e-86 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKKPOGGN_03543 8.8e-23 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKPOGGN_03544 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKKPOGGN_03545 3.7e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HKKPOGGN_03546 0.0 ydaO E amino acid
HKKPOGGN_03547 0.0 ydaN S Bacterial cellulose synthase subunit
HKKPOGGN_03548 1.4e-229 ydaM M Glycosyl transferase family group 2
HKKPOGGN_03549 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HKKPOGGN_03550 2.5e-147 ydaK T Diguanylate cyclase, GGDEF domain
HKKPOGGN_03551 4.6e-202 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKKPOGGN_03552 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKKPOGGN_03553 4.3e-74 lrpC K Transcriptional regulator
HKKPOGGN_03554 1.3e-47 ydzA EGP Major facilitator Superfamily
HKKPOGGN_03555 2.3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKKPOGGN_03556 5.2e-77 ydaG 1.4.3.5 S general stress protein
HKKPOGGN_03557 1.1e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKKPOGGN_03558 2.5e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HKKPOGGN_03559 9.7e-163 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_03560 8.5e-287 ydaB IQ acyl-CoA ligase
HKKPOGGN_03561 0.0 mtlR K transcriptional regulator, MtlR
HKKPOGGN_03562 2.2e-173 ydhF S Oxidoreductase
HKKPOGGN_03563 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HKKPOGGN_03564 5.1e-56 yczJ S biosynthesis
HKKPOGGN_03566 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
HKKPOGGN_03567 4.4e-130 kipR K Transcriptional regulator
HKKPOGGN_03568 1.6e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HKKPOGGN_03569 1e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HKKPOGGN_03570 1.8e-147 ycsI S Belongs to the D-glutamate cyclase family
HKKPOGGN_03571 2.3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HKKPOGGN_03572 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
HKKPOGGN_03573 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKKPOGGN_03575 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKKPOGGN_03576 4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HKKPOGGN_03577 8.8e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HKKPOGGN_03578 6e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HKKPOGGN_03579 6e-55
HKKPOGGN_03580 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HKKPOGGN_03581 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
HKKPOGGN_03582 1.9e-96 ycnI S protein conserved in bacteria
HKKPOGGN_03583 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKPOGGN_03584 3.6e-149 glcU U Glucose uptake
HKKPOGGN_03585 1.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKPOGGN_03586 4.5e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKPOGGN_03587 1.4e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKPOGGN_03588 1.3e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HKKPOGGN_03589 3.6e-45 ycnE S Monooxygenase
HKKPOGGN_03590 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HKKPOGGN_03591 2.7e-152 ycnC K Transcriptional regulator
HKKPOGGN_03592 4.3e-248 ycnB EGP Major facilitator Superfamily
HKKPOGGN_03593 1.6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HKKPOGGN_03594 3.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HKKPOGGN_03595 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_03596 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKPOGGN_03597 3.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKKPOGGN_03600 1.5e-81 S aspartate phosphatase
HKKPOGGN_03601 2.4e-259 T PhoQ Sensor
HKKPOGGN_03602 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKPOGGN_03603 9e-230 yclI V ABC transporter (permease) YclI
HKKPOGGN_03604 6e-123 yclH P ABC transporter
HKKPOGGN_03605 1.6e-252 yxeQ S MmgE/PrpD family
HKKPOGGN_03606 2.3e-215 yxeP 3.5.1.47 E hydrolase activity
HKKPOGGN_03607 2.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HKKPOGGN_03608 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HKKPOGGN_03609 6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
HKKPOGGN_03610 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKPOGGN_03611 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKPOGGN_03612 5.6e-195 gerKB F Spore germination protein
HKKPOGGN_03613 3e-234 gerKC S spore germination
HKKPOGGN_03614 1.6e-283 gerKA EG Spore germination protein
HKKPOGGN_03616 2.4e-277 yclG M Pectate lyase superfamily protein
HKKPOGGN_03617 5.4e-270 dtpT E amino acid peptide transporter
HKKPOGGN_03618 5.4e-75 yclD
HKKPOGGN_03619 2e-38 bsdD 4.1.1.61 S response to toxic substance
HKKPOGGN_03620 1.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HKKPOGGN_03621 6e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKKPOGGN_03622 9.6e-158 bsdA K LysR substrate binding domain
HKKPOGGN_03623 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKKPOGGN_03624 1.4e-119 tcyB P COG0765 ABC-type amino acid transport system, permease component
HKKPOGGN_03625 3.4e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKPOGGN_03626 1.3e-111 yczE S membrane
HKKPOGGN_03627 5.5e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HKKPOGGN_03628 2.6e-247 ycxD K GntR family transcriptional regulator
HKKPOGGN_03629 1.7e-168 ycxC EG EamA-like transporter family
HKKPOGGN_03630 1.4e-63 S YcxB-like protein
HKKPOGGN_03631 2.1e-249 bamJ E Aminotransferase class I and II
HKKPOGGN_03632 1.3e-139 srfAD Q thioesterase
HKKPOGGN_03633 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HKKPOGGN_03634 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKPOGGN_03635 3.2e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
HKKPOGGN_03636 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HKKPOGGN_03637 1.7e-75 gerD
HKKPOGGN_03638 2.5e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKKPOGGN_03639 1.8e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKPOGGN_03640 1e-78 ybaK S Protein of unknown function (DUF2521)
HKKPOGGN_03641 1.4e-81 yizA S Damage-inducible protein DinB
HKKPOGGN_03642 8.2e-145 ybaJ Q Methyltransferase domain
HKKPOGGN_03643 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HKKPOGGN_03644 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKKPOGGN_03645 5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKKPOGGN_03646 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKPOGGN_03647 1.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKPOGGN_03648 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKPOGGN_03649 4.7e-58 rplQ J Ribosomal protein L17
HKKPOGGN_03650 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKPOGGN_03651 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKKPOGGN_03652 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKKPOGGN_03653 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKKPOGGN_03654 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKKPOGGN_03655 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
HKKPOGGN_03656 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKKPOGGN_03657 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKKPOGGN_03658 4.1e-72 rplO J binds to the 23S rRNA
HKKPOGGN_03659 1.9e-23 rpmD J Ribosomal protein L30
HKKPOGGN_03660 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKKPOGGN_03661 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKKPOGGN_03662 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKKPOGGN_03663 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKKPOGGN_03664 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKKPOGGN_03665 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKKPOGGN_03666 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKKPOGGN_03667 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKKPOGGN_03668 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKKPOGGN_03669 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HKKPOGGN_03670 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKKPOGGN_03671 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKKPOGGN_03672 2.1e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKKPOGGN_03673 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKKPOGGN_03674 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKKPOGGN_03675 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKKPOGGN_03676 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HKKPOGGN_03677 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKKPOGGN_03678 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKKPOGGN_03679 2.4e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HKKPOGGN_03680 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKKPOGGN_03681 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKKPOGGN_03682 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKKPOGGN_03683 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKKPOGGN_03684 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HKKPOGGN_03685 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKPOGGN_03686 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKPOGGN_03687 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
HKKPOGGN_03688 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKKPOGGN_03689 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKKPOGGN_03690 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKKPOGGN_03691 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKKPOGGN_03692 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HKKPOGGN_03693 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKKPOGGN_03694 8.9e-116 sigH K Belongs to the sigma-70 factor family
HKKPOGGN_03695 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HKKPOGGN_03696 2.2e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKKPOGGN_03697 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKKPOGGN_03698 2.4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKKPOGGN_03699 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HKKPOGGN_03700 1.4e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKKPOGGN_03701 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKKPOGGN_03702 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKKPOGGN_03703 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HKKPOGGN_03704 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HKKPOGGN_03705 3.5e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKKPOGGN_03706 0.0 clpC O Belongs to the ClpA ClpB family
HKKPOGGN_03707 1.2e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HKKPOGGN_03708 2.1e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HKKPOGGN_03709 7.5e-77 ctsR K Belongs to the CtsR family
HKKPOGGN_03710 2.2e-30 csfB S Inhibitor of sigma-G Gin
HKKPOGGN_03711 5.6e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKKPOGGN_03712 6.4e-191 yaaN P Belongs to the TelA family
HKKPOGGN_03713 9.9e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HKKPOGGN_03714 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKKPOGGN_03715 7.5e-55 yaaQ S protein conserved in bacteria
HKKPOGGN_03716 1.2e-71 yaaR S protein conserved in bacteria
HKKPOGGN_03717 4.5e-180 holB 2.7.7.7 L DNA polymerase III
HKKPOGGN_03718 8.8e-145 yaaT S stage 0 sporulation protein
HKKPOGGN_03719 7.7e-37 yabA L Involved in initiation control of chromosome replication
HKKPOGGN_03720 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HKKPOGGN_03721 5.2e-47 yazA L endonuclease containing a URI domain
HKKPOGGN_03722 1.9e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKKPOGGN_03723 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HKKPOGGN_03724 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKKPOGGN_03725 6.9e-144 tatD L hydrolase, TatD
HKKPOGGN_03726 9.1e-232 rpfB GH23 T protein conserved in bacteria
HKKPOGGN_03727 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKKPOGGN_03728 4.3e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKKPOGGN_03729 1.9e-145 yabG S peptidase
HKKPOGGN_03730 2.3e-38 veg S protein conserved in bacteria
HKKPOGGN_03731 2.9e-27 sspF S DNA topological change
HKKPOGGN_03732 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKKPOGGN_03733 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKKPOGGN_03734 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HKKPOGGN_03735 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HKKPOGGN_03736 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKKPOGGN_03737 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKKPOGGN_03738 1e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKKPOGGN_03739 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKKPOGGN_03740 3.7e-40 yabK S Peptide ABC transporter permease
HKKPOGGN_03741 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKKPOGGN_03742 6.2e-91 spoVT K stage V sporulation protein
HKKPOGGN_03743 3.3e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKPOGGN_03744 1e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HKKPOGGN_03745 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKKPOGGN_03746 1.9e-49 yabP S Sporulation protein YabP
HKKPOGGN_03747 9.9e-104 yabQ S spore cortex biosynthesis protein
HKKPOGGN_03748 2.3e-52 divIC D Septum formation initiator
HKKPOGGN_03749 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HKKPOGGN_03752 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HKKPOGGN_03753 3.5e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
HKKPOGGN_03754 4.7e-185 KLT serine threonine protein kinase
HKKPOGGN_03755 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKKPOGGN_03756 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKKPOGGN_03757 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKKPOGGN_03758 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKKPOGGN_03759 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKKPOGGN_03760 2.5e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HKKPOGGN_03761 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKKPOGGN_03762 5.7e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKKPOGGN_03763 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HKKPOGGN_03764 8.5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HKKPOGGN_03765 4.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKKPOGGN_03766 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKKPOGGN_03767 3.2e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKKPOGGN_03768 4.5e-29 yazB K transcriptional
HKKPOGGN_03769 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKKPOGGN_03770 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)