ORF_ID e_value Gene_name EC_number CAZy COGs Description
MIHOOLGA_00004 2e-08
MIHOOLGA_00011 2e-08
MIHOOLGA_00016 3.4e-39 S COG NOG14552 non supervised orthologous group
MIHOOLGA_00017 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_00018 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_00019 1.8e-42 M nucleic acid phosphodiester bond hydrolysis
MIHOOLGA_00020 2.9e-29
MIHOOLGA_00021 4.9e-40
MIHOOLGA_00022 2.8e-24
MIHOOLGA_00023 7e-261 glnA 6.3.1.2 E glutamine synthetase
MIHOOLGA_00024 1.1e-68 glnR K transcriptional
MIHOOLGA_00025 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MIHOOLGA_00026 6.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIHOOLGA_00027 1.7e-176 spoVK O stage V sporulation protein K
MIHOOLGA_00028 6.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIHOOLGA_00029 1e-108 ymaB
MIHOOLGA_00030 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIHOOLGA_00031 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIHOOLGA_00032 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MIHOOLGA_00033 4.5e-22 ymzA
MIHOOLGA_00034 4.1e-22
MIHOOLGA_00035 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MIHOOLGA_00036 6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIHOOLGA_00037 2.1e-46 ymaF S YmaF family
MIHOOLGA_00039 2.1e-49 ebrA P Small Multidrug Resistance protein
MIHOOLGA_00040 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MIHOOLGA_00041 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MIHOOLGA_00042 2.1e-126 ymaC S Replication protein
MIHOOLGA_00043 1.9e-07 K Transcriptional regulator
MIHOOLGA_00044 3.3e-250 aprX O Belongs to the peptidase S8 family
MIHOOLGA_00045 1.8e-161 ymaE S Metallo-beta-lactamase superfamily
MIHOOLGA_00046 1.7e-60 ymzB
MIHOOLGA_00047 6e-106 pksA K Transcriptional regulator
MIHOOLGA_00048 1.8e-96 ymcC S Membrane
MIHOOLGA_00050 5.1e-70 S Regulatory protein YrvL
MIHOOLGA_00051 6e-08 S Terminase
MIHOOLGA_00052 5.5e-37 S Phage terminase, small subunit
MIHOOLGA_00054 1.2e-22
MIHOOLGA_00055 6.5e-19 L Phage integrase family
MIHOOLGA_00056 2.3e-31 L Phage integrase family
MIHOOLGA_00057 8.2e-22 wecC 1.1.1.336 M ArpU family transcriptional regulator
MIHOOLGA_00058 9.4e-14 wecC 1.1.1.336 M ArpU family transcriptional regulator
MIHOOLGA_00064 2.7e-07 yqaO S Phage-like element PBSX protein XtrA
MIHOOLGA_00065 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MIHOOLGA_00066 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIHOOLGA_00067 2.2e-88 cotE S Spore coat protein
MIHOOLGA_00068 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MIHOOLGA_00069 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIHOOLGA_00070 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MIHOOLGA_00071 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MIHOOLGA_00072 1.2e-36 spoVS S Stage V sporulation protein S
MIHOOLGA_00073 1.9e-152 ymdB S protein conserved in bacteria
MIHOOLGA_00074 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MIHOOLGA_00075 7.7e-211 pbpX V Beta-lactamase
MIHOOLGA_00076 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIHOOLGA_00077 4e-234 cinA 3.5.1.42 S Belongs to the CinA family
MIHOOLGA_00078 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIHOOLGA_00079 6.3e-120 ymfM S protein conserved in bacteria
MIHOOLGA_00080 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MIHOOLGA_00081 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MIHOOLGA_00082 6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MIHOOLGA_00083 1.1e-239 ymfH S zinc protease
MIHOOLGA_00084 2.7e-233 ymfF S Peptidase M16
MIHOOLGA_00085 1.5e-206 ymfD EGP Major facilitator Superfamily
MIHOOLGA_00086 1.4e-133 ymfC K Transcriptional regulator
MIHOOLGA_00087 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MIHOOLGA_00088 2.9e-31 S YlzJ-like protein
MIHOOLGA_00089 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MIHOOLGA_00090 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIHOOLGA_00091 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIHOOLGA_00092 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MIHOOLGA_00093 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIHOOLGA_00094 1.8e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MIHOOLGA_00095 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MIHOOLGA_00096 2.6e-42 ymxH S YlmC YmxH family
MIHOOLGA_00097 4.4e-233 pepR S Belongs to the peptidase M16 family
MIHOOLGA_00098 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MIHOOLGA_00099 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIHOOLGA_00100 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIHOOLGA_00101 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MIHOOLGA_00102 4.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIHOOLGA_00103 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIHOOLGA_00104 3.9e-44 ylxP S protein conserved in bacteria
MIHOOLGA_00105 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIHOOLGA_00106 3.1e-47 ylxQ J ribosomal protein
MIHOOLGA_00107 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MIHOOLGA_00108 1.1e-203 nusA K Participates in both transcription termination and antitermination
MIHOOLGA_00109 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MIHOOLGA_00110 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIHOOLGA_00111 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIHOOLGA_00112 7.7e-233 rasP M zinc metalloprotease
MIHOOLGA_00113 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIHOOLGA_00114 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MIHOOLGA_00115 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIHOOLGA_00116 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIHOOLGA_00117 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MIHOOLGA_00118 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIHOOLGA_00119 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MIHOOLGA_00120 4.3e-78 ylxL
MIHOOLGA_00121 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_00122 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MIHOOLGA_00123 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MIHOOLGA_00124 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MIHOOLGA_00125 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MIHOOLGA_00126 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MIHOOLGA_00127 7.5e-158 flhG D Belongs to the ParA family
MIHOOLGA_00128 5.7e-200 flhF N Flagellar biosynthesis regulator FlhF
MIHOOLGA_00129 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIHOOLGA_00130 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIHOOLGA_00131 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MIHOOLGA_00132 2.2e-36 fliQ N Role in flagellar biosynthesis
MIHOOLGA_00133 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MIHOOLGA_00134 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
MIHOOLGA_00135 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MIHOOLGA_00136 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MIHOOLGA_00137 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIHOOLGA_00138 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MIHOOLGA_00139 8.2e-140 flgG N Flagellar basal body rod
MIHOOLGA_00140 1.7e-72 flgD N Flagellar basal body rod modification protein
MIHOOLGA_00141 8.6e-220 fliK N Flagellar hook-length control protein
MIHOOLGA_00142 7.7e-37 ylxF S MgtE intracellular N domain
MIHOOLGA_00143 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MIHOOLGA_00144 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MIHOOLGA_00145 4.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MIHOOLGA_00146 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIHOOLGA_00147 5.9e-254 fliF N The M ring may be actively involved in energy transduction
MIHOOLGA_00148 1.9e-31 fliE N Flagellar hook-basal body
MIHOOLGA_00149 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MIHOOLGA_00150 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MIHOOLGA_00151 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MIHOOLGA_00152 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MIHOOLGA_00153 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIHOOLGA_00154 2.5e-169 xerC L tyrosine recombinase XerC
MIHOOLGA_00155 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MIHOOLGA_00156 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIHOOLGA_00157 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MIHOOLGA_00158 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIHOOLGA_00159 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIHOOLGA_00160 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MIHOOLGA_00161 1.8e-280 ylqG
MIHOOLGA_00162 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIHOOLGA_00163 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIHOOLGA_00164 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIHOOLGA_00165 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MIHOOLGA_00166 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIHOOLGA_00167 1.8e-60 ylqD S YlqD protein
MIHOOLGA_00168 4.5e-36 ylqC S Belongs to the UPF0109 family
MIHOOLGA_00169 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MIHOOLGA_00170 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIHOOLGA_00171 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MIHOOLGA_00172 3.2e-125 S Phosphotransferase enzyme family
MIHOOLGA_00173 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIHOOLGA_00174 0.0 smc D Required for chromosome condensation and partitioning
MIHOOLGA_00175 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIHOOLGA_00176 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIHOOLGA_00177 6.1e-129 IQ reductase
MIHOOLGA_00178 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MIHOOLGA_00179 1.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MIHOOLGA_00180 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MIHOOLGA_00181 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIHOOLGA_00182 2.1e-155 sdaAA 4.3.1.17 E L-serine dehydratase
MIHOOLGA_00183 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MIHOOLGA_00184 1.5e-300 yloV S kinase related to dihydroxyacetone kinase
MIHOOLGA_00185 5.5e-59 asp S protein conserved in bacteria
MIHOOLGA_00186 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MIHOOLGA_00187 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MIHOOLGA_00188 6.1e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MIHOOLGA_00189 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MIHOOLGA_00190 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MIHOOLGA_00191 1.6e-140 stp 3.1.3.16 T phosphatase
MIHOOLGA_00192 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIHOOLGA_00193 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIHOOLGA_00194 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIHOOLGA_00195 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIHOOLGA_00196 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIHOOLGA_00197 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIHOOLGA_00198 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIHOOLGA_00199 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MIHOOLGA_00200 1.5e-40 ylzA S Belongs to the UPF0296 family
MIHOOLGA_00201 3.1e-156 yloC S stress-induced protein
MIHOOLGA_00202 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MIHOOLGA_00203 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MIHOOLGA_00204 1.8e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MIHOOLGA_00205 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MIHOOLGA_00206 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIHOOLGA_00207 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MIHOOLGA_00208 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MIHOOLGA_00209 3.2e-179 cysP P phosphate transporter
MIHOOLGA_00210 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MIHOOLGA_00212 2.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIHOOLGA_00213 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MIHOOLGA_00214 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIHOOLGA_00215 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MIHOOLGA_00216 0.0 carB 6.3.5.5 F Belongs to the CarB family
MIHOOLGA_00217 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIHOOLGA_00218 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIHOOLGA_00219 1.2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MIHOOLGA_00220 7.6e-231 pyrP F Xanthine uracil
MIHOOLGA_00221 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MIHOOLGA_00222 5.5e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIHOOLGA_00223 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIHOOLGA_00224 2.2e-63 dksA T COG1734 DnaK suppressor protein
MIHOOLGA_00225 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIHOOLGA_00226 2.6e-67 divIVA D Cell division initiation protein
MIHOOLGA_00227 9.7e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MIHOOLGA_00228 1.3e-39 yggT S membrane
MIHOOLGA_00229 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIHOOLGA_00230 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIHOOLGA_00231 7.8e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MIHOOLGA_00232 2.4e-37 ylmC S sporulation protein
MIHOOLGA_00233 9.9e-252 argE 3.5.1.16 E Acetylornithine deacetylase
MIHOOLGA_00234 2.6e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MIHOOLGA_00235 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_00236 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_00237 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MIHOOLGA_00238 0.0 bpr O COG1404 Subtilisin-like serine proteases
MIHOOLGA_00239 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIHOOLGA_00240 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MIHOOLGA_00241 6.2e-58 sbp S small basic protein
MIHOOLGA_00242 5.1e-102 ylxX S protein conserved in bacteria
MIHOOLGA_00243 7e-103 ylxW S protein conserved in bacteria
MIHOOLGA_00244 1.3e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MIHOOLGA_00245 9e-167 murB 1.3.1.98 M cell wall formation
MIHOOLGA_00246 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIHOOLGA_00247 5.7e-186 spoVE D Belongs to the SEDS family
MIHOOLGA_00248 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIHOOLGA_00249 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIHOOLGA_00250 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIHOOLGA_00251 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MIHOOLGA_00252 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MIHOOLGA_00253 3.7e-44 ftsL D Essential cell division protein
MIHOOLGA_00254 5.2e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIHOOLGA_00255 2.9e-78 mraZ K Belongs to the MraZ family
MIHOOLGA_00256 3.5e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MIHOOLGA_00257 3.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIHOOLGA_00258 1.5e-88 ylbP K n-acetyltransferase
MIHOOLGA_00259 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MIHOOLGA_00260 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MIHOOLGA_00261 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MIHOOLGA_00263 2.8e-235 ylbM S Belongs to the UPF0348 family
MIHOOLGA_00264 3.4e-186 ylbL T Belongs to the peptidase S16 family
MIHOOLGA_00265 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MIHOOLGA_00266 3.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
MIHOOLGA_00267 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIHOOLGA_00268 1.9e-95 rsmD 2.1.1.171 L Methyltransferase
MIHOOLGA_00269 7.5e-39 ylbG S UPF0298 protein
MIHOOLGA_00270 1.8e-75 ylbF S Belongs to the UPF0342 family
MIHOOLGA_00271 6.7e-37 ylbE S YlbE-like protein
MIHOOLGA_00272 2.6e-62 ylbD S Putative coat protein
MIHOOLGA_00273 4.8e-199 ylbC S protein with SCP PR1 domains
MIHOOLGA_00274 2.6e-74 ylbB T COG0517 FOG CBS domain
MIHOOLGA_00275 7e-62 ylbA S YugN-like family
MIHOOLGA_00276 3e-167 ctaG S cytochrome c oxidase
MIHOOLGA_00277 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MIHOOLGA_00278 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MIHOOLGA_00279 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIHOOLGA_00280 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MIHOOLGA_00281 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MIHOOLGA_00282 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MIHOOLGA_00283 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MIHOOLGA_00284 2.7e-211 ftsW D Belongs to the SEDS family
MIHOOLGA_00285 8.7e-44 ylaN S Belongs to the UPF0358 family
MIHOOLGA_00286 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MIHOOLGA_00287 3.9e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIHOOLGA_00288 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MIHOOLGA_00289 4e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIHOOLGA_00290 2.5e-32 ylaI S protein conserved in bacteria
MIHOOLGA_00291 4.2e-47 ylaH S YlaH-like protein
MIHOOLGA_00292 0.0 typA T GTP-binding protein TypA
MIHOOLGA_00293 8.2e-22 S Family of unknown function (DUF5325)
MIHOOLGA_00294 2.6e-37 ylaE
MIHOOLGA_00295 1.2e-11 sigC S Putative zinc-finger
MIHOOLGA_00296 1.5e-57 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_00297 2.7e-42 ylaB
MIHOOLGA_00298 0.0 ylaA
MIHOOLGA_00299 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MIHOOLGA_00300 1.8e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MIHOOLGA_00301 1.7e-76 ykzC S Acetyltransferase (GNAT) family
MIHOOLGA_00302 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
MIHOOLGA_00303 7.1e-26 ykzI
MIHOOLGA_00304 4.6e-117 yktB S Belongs to the UPF0637 family
MIHOOLGA_00305 6.5e-41 yktA S Belongs to the UPF0223 family
MIHOOLGA_00306 1e-276 speA 4.1.1.19 E Arginine
MIHOOLGA_00307 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MIHOOLGA_00308 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIHOOLGA_00309 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIHOOLGA_00310 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIHOOLGA_00311 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIHOOLGA_00312 1.1e-107 recN L Putative cell-wall binding lipoprotein
MIHOOLGA_00314 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIHOOLGA_00315 5.5e-147 ykrA S hydrolases of the HAD superfamily
MIHOOLGA_00316 8.2e-31 ykzG S Belongs to the UPF0356 family
MIHOOLGA_00317 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIHOOLGA_00318 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MIHOOLGA_00319 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MIHOOLGA_00320 1.9e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MIHOOLGA_00321 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MIHOOLGA_00322 1.5e-43 abrB K of stationary sporulation gene expression
MIHOOLGA_00323 7.7e-183 mreB D Rod-share determining protein MreBH
MIHOOLGA_00324 1.1e-12 S Uncharacterized protein YkpC
MIHOOLGA_00325 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MIHOOLGA_00326 1.3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIHOOLGA_00327 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIHOOLGA_00328 8.1e-39 ykoA
MIHOOLGA_00329 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIHOOLGA_00330 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MIHOOLGA_00331 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MIHOOLGA_00332 3.1e-136 fruR K Transcriptional regulator
MIHOOLGA_00333 5.6e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIHOOLGA_00334 2.5e-124 macB V ABC transporter, ATP-binding protein
MIHOOLGA_00335 1.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIHOOLGA_00336 2.9e-117 yknW S Yip1 domain
MIHOOLGA_00337 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIHOOLGA_00338 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIHOOLGA_00339 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MIHOOLGA_00340 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MIHOOLGA_00341 5.5e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MIHOOLGA_00342 3.4e-244 moeA 2.10.1.1 H molybdopterin
MIHOOLGA_00343 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MIHOOLGA_00344 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MIHOOLGA_00345 3.5e-145 yknT
MIHOOLGA_00346 5.8e-95 rok K Repressor of ComK
MIHOOLGA_00347 2.4e-80 ykuV CO thiol-disulfide
MIHOOLGA_00348 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MIHOOLGA_00349 8.8e-142 ykuT M Mechanosensitive ion channel
MIHOOLGA_00350 9e-37 ykuS S Belongs to the UPF0180 family
MIHOOLGA_00351 1.9e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MIHOOLGA_00352 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MIHOOLGA_00353 3.9e-78 fld C Flavodoxin
MIHOOLGA_00354 1.3e-173 ykuO
MIHOOLGA_00355 3.5e-85 fld C Flavodoxin domain
MIHOOLGA_00356 3.5e-168 ccpC K Transcriptional regulator
MIHOOLGA_00357 1.6e-76 ykuL S CBS domain
MIHOOLGA_00358 3.9e-27 ykzF S Antirepressor AbbA
MIHOOLGA_00359 4.4e-94 ykuK S Ribonuclease H-like
MIHOOLGA_00360 3.9e-37 ykuJ S protein conserved in bacteria
MIHOOLGA_00361 6.7e-234 ykuI T Diguanylate phosphodiesterase
MIHOOLGA_00362 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_00363 3.6e-165 ykuE S Metallophosphoesterase
MIHOOLGA_00364 1.8e-87 ykuD S protein conserved in bacteria
MIHOOLGA_00365 9.9e-236 ykuC EGP Major facilitator Superfamily
MIHOOLGA_00366 1.7e-84 ykyB S YkyB-like protein
MIHOOLGA_00367 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MIHOOLGA_00368 2.2e-15
MIHOOLGA_00369 6.3e-221 patA 2.6.1.1 E Aminotransferase
MIHOOLGA_00370 0.0 pilS 2.7.13.3 T Histidine kinase
MIHOOLGA_00371 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MIHOOLGA_00372 5.7e-122 ykwD J protein with SCP PR1 domains
MIHOOLGA_00373 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MIHOOLGA_00374 3.2e-262 mcpC NT chemotaxis protein
MIHOOLGA_00375 7.3e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_00376 6.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
MIHOOLGA_00377 7.2e-39 splA S Transcriptional regulator
MIHOOLGA_00378 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIHOOLGA_00379 2.1e-39 ptsH G phosphocarrier protein HPr
MIHOOLGA_00380 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_00381 7.6e-128 glcT K antiterminator
MIHOOLGA_00383 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MIHOOLGA_00385 8.2e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIHOOLGA_00386 2.3e-09
MIHOOLGA_00387 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIHOOLGA_00388 4.9e-90 stoA CO thiol-disulfide
MIHOOLGA_00389 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_00390 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
MIHOOLGA_00391 2.7e-28
MIHOOLGA_00392 6e-25 ykvS S protein conserved in bacteria
MIHOOLGA_00393 2.1e-45 ykvR S Protein of unknown function (DUF3219)
MIHOOLGA_00394 3.6e-152 G Glycosyl hydrolases family 18
MIHOOLGA_00395 3.5e-35 3.5.1.104 M LysM domain
MIHOOLGA_00396 2.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
MIHOOLGA_00397 1.6e-132 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_00398 2e-61 ykvN K Transcriptional regulator
MIHOOLGA_00399 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIHOOLGA_00400 1.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MIHOOLGA_00401 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MIHOOLGA_00402 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MIHOOLGA_00403 6.2e-180 ykvI S membrane
MIHOOLGA_00404 0.0 clpE O Belongs to the ClpA ClpB family
MIHOOLGA_00405 1e-137 motA N flagellar motor
MIHOOLGA_00406 2.5e-125 motB N Flagellar motor protein
MIHOOLGA_00407 1.3e-75 ykvE K transcriptional
MIHOOLGA_00408 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MIHOOLGA_00409 6.8e-64 eag
MIHOOLGA_00410 6.4e-09 S Spo0E like sporulation regulatory protein
MIHOOLGA_00411 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
MIHOOLGA_00412 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MIHOOLGA_00413 1.4e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MIHOOLGA_00414 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MIHOOLGA_00415 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MIHOOLGA_00416 2e-227 mtnE 2.6.1.83 E Aminotransferase
MIHOOLGA_00417 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIHOOLGA_00418 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MIHOOLGA_00419 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MIHOOLGA_00421 1.7e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIHOOLGA_00422 0.0 kinE 2.7.13.3 T Histidine kinase
MIHOOLGA_00423 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MIHOOLGA_00424 2.2e-19 ykzE
MIHOOLGA_00425 1.2e-10 ydfR S Protein of unknown function (DUF421)
MIHOOLGA_00426 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MIHOOLGA_00427 3.5e-155 htpX O Belongs to the peptidase M48B family
MIHOOLGA_00428 1.5e-124 ykrK S Domain of unknown function (DUF1836)
MIHOOLGA_00429 1.9e-26 sspD S small acid-soluble spore protein
MIHOOLGA_00430 1.5e-105 rsgI S Anti-sigma factor N-terminus
MIHOOLGA_00431 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_00432 1.8e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MIHOOLGA_00433 3.5e-109 ykoX S membrane-associated protein
MIHOOLGA_00434 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MIHOOLGA_00435 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MIHOOLGA_00436 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MIHOOLGA_00437 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_00438 0.0 ykoS
MIHOOLGA_00439 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MIHOOLGA_00440 1.1e-98 ykoP G polysaccharide deacetylase
MIHOOLGA_00441 2.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MIHOOLGA_00442 1.3e-81 mhqR K transcriptional
MIHOOLGA_00443 6.9e-26 ykoL
MIHOOLGA_00444 5.9e-18
MIHOOLGA_00445 1.4e-53 tnrA K transcriptional
MIHOOLGA_00446 2.2e-222 mgtE P Acts as a magnesium transporter
MIHOOLGA_00449 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MIHOOLGA_00450 6.2e-112 ykoI S Peptidase propeptide and YPEB domain
MIHOOLGA_00451 3e-243 ykoH 2.7.13.3 T Histidine kinase
MIHOOLGA_00452 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_00453 5.7e-109 ykoF S YKOF-related Family
MIHOOLGA_00454 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MIHOOLGA_00455 7.2e-308 P ABC transporter, ATP-binding protein
MIHOOLGA_00456 4e-136 ykoC P Cobalt transport protein
MIHOOLGA_00457 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIHOOLGA_00458 6.6e-176 isp O Belongs to the peptidase S8 family
MIHOOLGA_00459 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIHOOLGA_00460 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MIHOOLGA_00461 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MIHOOLGA_00462 4.4e-74 ohrR K COG1846 Transcriptional regulators
MIHOOLGA_00463 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MIHOOLGA_00464 2.6e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIHOOLGA_00465 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIHOOLGA_00466 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MIHOOLGA_00467 7e-50 ykkD P Multidrug resistance protein
MIHOOLGA_00468 3.5e-55 ykkC P Multidrug resistance protein
MIHOOLGA_00469 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIHOOLGA_00470 8.8e-98 ykkA S Protein of unknown function (DUF664)
MIHOOLGA_00471 2.7e-129 ykjA S Protein of unknown function (DUF421)
MIHOOLGA_00472 1.3e-10
MIHOOLGA_00473 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIHOOLGA_00474 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MIHOOLGA_00475 3.8e-151 ykgA E Amidinotransferase
MIHOOLGA_00476 1.8e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MIHOOLGA_00477 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
MIHOOLGA_00478 1.8e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MIHOOLGA_00479 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIHOOLGA_00480 3.5e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MIHOOLGA_00482 0.0 dppE E ABC transporter substrate-binding protein
MIHOOLGA_00483 1.3e-185 dppD P Belongs to the ABC transporter superfamily
MIHOOLGA_00484 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00485 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00486 1.1e-152 dppA E D-aminopeptidase
MIHOOLGA_00487 8.2e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MIHOOLGA_00488 2e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIHOOLGA_00490 3.8e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_00491 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIHOOLGA_00492 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MIHOOLGA_00493 2.3e-240 steT E amino acid
MIHOOLGA_00494 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MIHOOLGA_00495 5.8e-175 pit P phosphate transporter
MIHOOLGA_00496 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MIHOOLGA_00497 6.7e-23 spoIISB S Stage II sporulation protein SB
MIHOOLGA_00498 8.6e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIHOOLGA_00499 9.3e-40 xhlB S SPP1 phage holin
MIHOOLGA_00500 2.8e-39 xhlA S Haemolysin XhlA
MIHOOLGA_00501 2.8e-154 xepA
MIHOOLGA_00502 7.1e-22 xkdX
MIHOOLGA_00503 3.9e-51 xkdW S XkdW protein
MIHOOLGA_00504 0.0
MIHOOLGA_00505 3.3e-40
MIHOOLGA_00506 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MIHOOLGA_00507 3.9e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MIHOOLGA_00508 4.5e-68 xkdS S Protein of unknown function (DUF2634)
MIHOOLGA_00509 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MIHOOLGA_00510 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MIHOOLGA_00511 1.7e-117 xkdP S Lysin motif
MIHOOLGA_00512 1.5e-253 xkdO L Transglycosylase SLT domain
MIHOOLGA_00513 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
MIHOOLGA_00514 1e-75 xkdM S Phage tail tube protein
MIHOOLGA_00515 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MIHOOLGA_00516 1.9e-77 xkdJ
MIHOOLGA_00517 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
MIHOOLGA_00518 1.5e-64 yqbH S Domain of unknown function (DUF3599)
MIHOOLGA_00519 8.7e-63 yqbG S Protein of unknown function (DUF3199)
MIHOOLGA_00520 5.8e-169 xkdG S Phage capsid family
MIHOOLGA_00521 2.2e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MIHOOLGA_00522 4.6e-285 yqbA S portal protein
MIHOOLGA_00523 1.4e-253 xtmB S phage terminase, large subunit
MIHOOLGA_00524 4.1e-139 xtmA L phage terminase small subunit
MIHOOLGA_00525 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MIHOOLGA_00526 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MIHOOLGA_00529 4.1e-118 xkdC L Bacterial dnaA protein
MIHOOLGA_00530 5e-156 xkdB K sequence-specific DNA binding
MIHOOLGA_00532 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MIHOOLGA_00533 1e-110 xkdA E IrrE N-terminal-like domain
MIHOOLGA_00534 4.4e-160 ydbD P Catalase
MIHOOLGA_00535 2.1e-111 yjqB S Pfam:DUF867
MIHOOLGA_00536 6.8e-60 yjqA S Bacterial PH domain
MIHOOLGA_00537 9.1e-162 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MIHOOLGA_00538 6.3e-41 S YCII-related domain
MIHOOLGA_00540 1e-212 S response regulator aspartate phosphatase
MIHOOLGA_00541 4.7e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MIHOOLGA_00542 5.2e-78 yjoA S DinB family
MIHOOLGA_00543 7.4e-130 MA20_18170 S membrane transporter protein
MIHOOLGA_00544 4.9e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MIHOOLGA_00545 3.2e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MIHOOLGA_00546 5.2e-184 exuR K transcriptional
MIHOOLGA_00547 3.1e-226 exuT G Sugar (and other) transporter
MIHOOLGA_00548 4.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_00549 3.1e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MIHOOLGA_00550 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MIHOOLGA_00551 3.9e-187 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MIHOOLGA_00552 1.1e-248 yjmB G symporter YjmB
MIHOOLGA_00553 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
MIHOOLGA_00554 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MIHOOLGA_00555 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MIHOOLGA_00556 1.4e-89 yjlB S Cupin domain
MIHOOLGA_00557 1.9e-175 yjlA EG Putative multidrug resistance efflux transporter
MIHOOLGA_00558 5.4e-133 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MIHOOLGA_00559 2.1e-121 ybbM S transport system, permease component
MIHOOLGA_00560 5.6e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIHOOLGA_00561 8.2e-30
MIHOOLGA_00562 1.1e-212 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MIHOOLGA_00563 2.2e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MIHOOLGA_00565 1.3e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MIHOOLGA_00567 3.7e-94 yjgD S Protein of unknown function (DUF1641)
MIHOOLGA_00568 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MIHOOLGA_00569 2e-103 yjgB S Domain of unknown function (DUF4309)
MIHOOLGA_00570 1.2e-45 T PhoQ Sensor
MIHOOLGA_00571 3.6e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
MIHOOLGA_00572 8.9e-20 yjfB S Putative motility protein
MIHOOLGA_00573 1.4e-81 S Protein of unknown function (DUF2690)
MIHOOLGA_00574 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
MIHOOLGA_00576 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MIHOOLGA_00577 1e-51 yjdJ S Domain of unknown function (DUF4306)
MIHOOLGA_00578 4.2e-29 S Domain of unknown function (DUF4177)
MIHOOLGA_00579 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIHOOLGA_00581 9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MIHOOLGA_00582 4.8e-51 yjdF S Protein of unknown function (DUF2992)
MIHOOLGA_00583 4.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MIHOOLGA_00584 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MIHOOLGA_00585 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MIHOOLGA_00587 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_00588 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MIHOOLGA_00590 9e-19
MIHOOLGA_00591 3.8e-37
MIHOOLGA_00595 3e-13 K Transcriptional regulator
MIHOOLGA_00597 6.6e-07 S Family of unknown function (DUF5316)
MIHOOLGA_00599 2.4e-41
MIHOOLGA_00600 7.5e-245 I Pfam Lipase (class 3)
MIHOOLGA_00601 9.5e-51 S Protein of unknown function (DUF1433)
MIHOOLGA_00602 4.5e-122 ynaC
MIHOOLGA_00603 6.6e-47 S Restriction endonuclease
MIHOOLGA_00604 2e-29
MIHOOLGA_00606 2.7e-98 K Helix-turn-helix domain
MIHOOLGA_00607 1.7e-07 K Cro/C1-type HTH DNA-binding domain
MIHOOLGA_00608 1.2e-75 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MIHOOLGA_00609 8.7e-62 L Integrase core domain
MIHOOLGA_00610 2.5e-50 L COG2963 Transposase and inactivated derivatives
MIHOOLGA_00611 3.1e-87
MIHOOLGA_00612 1.4e-07 S Helix-turn-helix domain
MIHOOLGA_00613 6.6e-15 K Helix-turn-helix XRE-family like proteins
MIHOOLGA_00614 4.7e-45 xre K Helix-turn-helix XRE-family like proteins
MIHOOLGA_00615 1.5e-49
MIHOOLGA_00616 2.6e-29 S Protein of unknown function (DUF4064)
MIHOOLGA_00618 5.2e-33 xkdA E IrrE N-terminal-like domain
MIHOOLGA_00619 3.3e-18 L Belongs to the 'phage' integrase family
MIHOOLGA_00620 1.9e-10 L Belongs to the 'phage' integrase family
MIHOOLGA_00622 9.5e-209 yjcL S Protein of unknown function (DUF819)
MIHOOLGA_00623 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
MIHOOLGA_00624 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIHOOLGA_00625 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIHOOLGA_00626 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
MIHOOLGA_00627 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MIHOOLGA_00628 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_00629 8.4e-38
MIHOOLGA_00630 0.0 yjcD 3.6.4.12 L DNA helicase
MIHOOLGA_00631 2.9e-38 spoVIF S Stage VI sporulation protein F
MIHOOLGA_00634 4.3e-56 yjcA S Protein of unknown function (DUF1360)
MIHOOLGA_00635 5.2e-55 cotV S Spore Coat Protein X and V domain
MIHOOLGA_00636 3.4e-23 cotW
MIHOOLGA_00637 2e-78 cotX S Spore Coat Protein X and V domain
MIHOOLGA_00638 7.6e-96 cotY S Spore coat protein Z
MIHOOLGA_00639 4.4e-82 cotZ S Spore coat protein
MIHOOLGA_00640 5.9e-54 yjbX S Spore coat protein
MIHOOLGA_00641 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MIHOOLGA_00642 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIHOOLGA_00643 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MIHOOLGA_00644 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIHOOLGA_00645 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MIHOOLGA_00646 9.8e-216 thiO 1.4.3.19 E Glycine oxidase
MIHOOLGA_00647 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MIHOOLGA_00648 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIHOOLGA_00649 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MIHOOLGA_00650 7.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MIHOOLGA_00651 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIHOOLGA_00652 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIHOOLGA_00653 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MIHOOLGA_00654 7.1e-62 yjbL S Belongs to the UPF0738 family
MIHOOLGA_00655 1.2e-100 yjbK S protein conserved in bacteria
MIHOOLGA_00656 1.2e-81 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MIHOOLGA_00657 3.7e-72 yjbI S Bacterial-like globin
MIHOOLGA_00658 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MIHOOLGA_00660 1.8e-20
MIHOOLGA_00661 0.0 pepF E oligoendopeptidase F
MIHOOLGA_00662 3.4e-219 yjbF S Competence protein
MIHOOLGA_00663 8.9e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIHOOLGA_00664 6e-112 yjbE P Integral membrane protein TerC family
MIHOOLGA_00665 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MIHOOLGA_00666 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_00667 5.4e-204 yjbB EGP Major Facilitator Superfamily
MIHOOLGA_00668 1.2e-171 oppF E Belongs to the ABC transporter superfamily
MIHOOLGA_00669 1.5e-197 oppD P Belongs to the ABC transporter superfamily
MIHOOLGA_00670 5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00671 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00672 0.0 oppA E ABC transporter substrate-binding protein
MIHOOLGA_00673 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MIHOOLGA_00674 5e-147 yjbA S Belongs to the UPF0736 family
MIHOOLGA_00675 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00676 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIHOOLGA_00677 1.6e-275 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MIHOOLGA_00678 2.7e-185 appF E Belongs to the ABC transporter superfamily
MIHOOLGA_00679 1.8e-184 appD P Belongs to the ABC transporter superfamily
MIHOOLGA_00680 9.5e-149 yjaZ O Zn-dependent protease
MIHOOLGA_00681 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MIHOOLGA_00682 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIHOOLGA_00683 2.7e-22 yjzB
MIHOOLGA_00684 7.3e-26 comZ S ComZ
MIHOOLGA_00685 2.5e-183 med S Transcriptional activator protein med
MIHOOLGA_00686 5.8e-100 yjaV
MIHOOLGA_00687 5.2e-141 yjaU I carboxylic ester hydrolase activity
MIHOOLGA_00688 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MIHOOLGA_00689 9.5e-28 yjzC S YjzC-like protein
MIHOOLGA_00690 1.1e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIHOOLGA_00691 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MIHOOLGA_00692 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIHOOLGA_00693 1.1e-214 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MIHOOLGA_00694 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MIHOOLGA_00695 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIHOOLGA_00696 2.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIHOOLGA_00697 1.7e-88 norB G Major Facilitator Superfamily
MIHOOLGA_00698 3.7e-268 yitY C D-arabinono-1,4-lactone oxidase
MIHOOLGA_00699 1.5e-22 pilT S Proteolipid membrane potential modulator
MIHOOLGA_00700 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MIHOOLGA_00701 1.4e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MIHOOLGA_00702 2.7e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MIHOOLGA_00704 1.2e-17 S Protein of unknown function (DUF3813)
MIHOOLGA_00705 5e-73 ipi S Intracellular proteinase inhibitor
MIHOOLGA_00706 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MIHOOLGA_00707 1.6e-157 yitS S protein conserved in bacteria
MIHOOLGA_00708 5.5e-308 nprB 3.4.24.28 E Peptidase M4
MIHOOLGA_00709 1.4e-44 yitR S Domain of unknown function (DUF3784)
MIHOOLGA_00710 2.9e-94
MIHOOLGA_00711 1.5e-58 K Transcriptional regulator PadR-like family
MIHOOLGA_00712 1.5e-97 S Sporulation delaying protein SdpA
MIHOOLGA_00713 2.8e-171
MIHOOLGA_00714 8.5e-94
MIHOOLGA_00715 6.9e-161 cvfB S protein conserved in bacteria
MIHOOLGA_00716 3.3e-54 yajQ S Belongs to the UPF0234 family
MIHOOLGA_00717 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MIHOOLGA_00718 1e-70 yjcF S Acetyltransferase (GNAT) domain
MIHOOLGA_00719 8.1e-154 yitH K Acetyltransferase (GNAT) domain
MIHOOLGA_00720 1.5e-228 yitG EGP Major facilitator Superfamily
MIHOOLGA_00721 6.6e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIHOOLGA_00722 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MIHOOLGA_00723 1.9e-141 yitD 4.4.1.19 S synthase
MIHOOLGA_00724 1.4e-124 comB 3.1.3.71 H Belongs to the ComB family
MIHOOLGA_00725 2.5e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MIHOOLGA_00726 9.3e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MIHOOLGA_00727 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MIHOOLGA_00728 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MIHOOLGA_00729 2e-35 mcbG S Pentapeptide repeats (9 copies)
MIHOOLGA_00730 2.2e-276 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_00731 2.3e-105 argO S Lysine exporter protein LysE YggA
MIHOOLGA_00732 8.2e-93 yisT S DinB family
MIHOOLGA_00733 5.4e-192 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MIHOOLGA_00735 2.4e-184 purR K helix_turn _helix lactose operon repressor
MIHOOLGA_00736 2.7e-160 yisR K Transcriptional regulator
MIHOOLGA_00737 4e-243 yisQ V Mate efflux family protein
MIHOOLGA_00738 1.3e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MIHOOLGA_00739 1.4e-87 yizA S Damage-inducible protein DinB
MIHOOLGA_00740 0.0 asnO 6.3.5.4 E Asparagine synthase
MIHOOLGA_00741 6.2e-102 yisN S Protein of unknown function (DUF2777)
MIHOOLGA_00742 0.0 wprA O Belongs to the peptidase S8 family
MIHOOLGA_00743 3.9e-57 yisL S UPF0344 protein
MIHOOLGA_00744 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MIHOOLGA_00745 1.5e-172 cotH M Spore Coat
MIHOOLGA_00746 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MIHOOLGA_00747 1.9e-33 gerPA S Spore germination protein
MIHOOLGA_00748 4e-34 gerPB S cell differentiation
MIHOOLGA_00749 5.3e-54 gerPC S Spore germination protein
MIHOOLGA_00750 6.3e-24 gerPD S Spore germination protein
MIHOOLGA_00751 8.8e-66 gerPE S Spore germination protein GerPE
MIHOOLGA_00752 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MIHOOLGA_00753 1.5e-49 yisB V COG1403 Restriction endonuclease
MIHOOLGA_00754 0.0 sbcC L COG0419 ATPase involved in DNA repair
MIHOOLGA_00755 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MIHOOLGA_00756 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MIHOOLGA_00757 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MIHOOLGA_00758 2.2e-78 yhjR S Rubrerythrin
MIHOOLGA_00759 0.0 S Sugar transport-related sRNA regulator N-term
MIHOOLGA_00760 3.9e-210 EGP Transmembrane secretion effector
MIHOOLGA_00761 4.2e-201 abrB S membrane
MIHOOLGA_00762 6.5e-187 yhjM 5.1.1.1 K Transcriptional regulator
MIHOOLGA_00763 1.6e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MIHOOLGA_00764 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MIHOOLGA_00765 7.9e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MIHOOLGA_00766 9.9e-214 glcP G Major Facilitator Superfamily
MIHOOLGA_00767 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_00768 6.6e-284 yhjG CH FAD binding domain
MIHOOLGA_00769 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MIHOOLGA_00770 9.1e-110 yhjE S SNARE associated Golgi protein
MIHOOLGA_00771 5e-60 yhjD
MIHOOLGA_00772 4.5e-26 yhjC S Protein of unknown function (DUF3311)
MIHOOLGA_00773 1.8e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIHOOLGA_00774 1.1e-40 yhjA S Excalibur calcium-binding domain
MIHOOLGA_00775 2.9e-165 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_00776 9.3e-109 comK K Competence transcription factor
MIHOOLGA_00777 1.3e-32 yhzC S IDEAL
MIHOOLGA_00778 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_00779 6.1e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MIHOOLGA_00780 1.7e-182 hemAT NT chemotaxis protein
MIHOOLGA_00781 4.2e-90 bioY S BioY family
MIHOOLGA_00782 6.2e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIHOOLGA_00783 2.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
MIHOOLGA_00784 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MIHOOLGA_00785 2.2e-155 yfmC M Periplasmic binding protein
MIHOOLGA_00786 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MIHOOLGA_00787 7.3e-77 VY92_01935 K acetyltransferase
MIHOOLGA_00788 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MIHOOLGA_00789 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MIHOOLGA_00790 2.1e-64 yhfM
MIHOOLGA_00791 2e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIHOOLGA_00792 1.9e-110 yhfK GM NmrA-like family
MIHOOLGA_00793 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MIHOOLGA_00794 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MIHOOLGA_00795 9.3e-20 yhfH S YhfH-like protein
MIHOOLGA_00796 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIHOOLGA_00797 3.7e-72 3.4.13.21 S ASCH
MIHOOLGA_00798 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MIHOOLGA_00799 2e-135 yhfC S Putative membrane peptidase family (DUF2324)
MIHOOLGA_00800 2.5e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIHOOLGA_00801 5e-238 yhgE S YhgE Pip N-terminal domain protein
MIHOOLGA_00802 5.4e-101 yhgD K Transcriptional regulator
MIHOOLGA_00803 9.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIHOOLGA_00804 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MIHOOLGA_00805 1.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MIHOOLGA_00806 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIHOOLGA_00807 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MIHOOLGA_00808 1.6e-33 1.15.1.2 C Rubrerythrin
MIHOOLGA_00809 2.1e-244 yhfA C membrane
MIHOOLGA_00810 1.2e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MIHOOLGA_00811 6.9e-114 ecsC S EcsC protein family
MIHOOLGA_00812 1.6e-214 ecsB U ABC transporter
MIHOOLGA_00813 4.6e-137 ecsA V transporter (ATP-binding protein)
MIHOOLGA_00814 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MIHOOLGA_00815 2.7e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIHOOLGA_00816 3.6e-80 trpP S Tryptophan transporter TrpP
MIHOOLGA_00817 7e-39 yhaH S YtxH-like protein
MIHOOLGA_00818 1e-113 hpr K Negative regulator of protease production and sporulation
MIHOOLGA_00819 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MIHOOLGA_00820 8.7e-90 yhaK S Putative zincin peptidase
MIHOOLGA_00821 3.2e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MIHOOLGA_00822 1.6e-21 yhaL S Sporulation protein YhaL
MIHOOLGA_00823 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MIHOOLGA_00824 0.0 yhaN L AAA domain
MIHOOLGA_00825 5.7e-225 yhaO L DNA repair exonuclease
MIHOOLGA_00826 8e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MIHOOLGA_00827 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MIHOOLGA_00828 1.1e-26 S YhzD-like protein
MIHOOLGA_00829 5.5e-78 yhaR 5.3.3.18 I enoyl-CoA hydratase
MIHOOLGA_00830 2.1e-42 yhaR 5.3.3.18 I enoyl-CoA hydratase
MIHOOLGA_00832 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MIHOOLGA_00833 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MIHOOLGA_00834 5.1e-292 hemZ H coproporphyrinogen III oxidase
MIHOOLGA_00835 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MIHOOLGA_00836 1.5e-205 yhaZ L DNA alkylation repair enzyme
MIHOOLGA_00837 9.5e-48 yheA S Belongs to the UPF0342 family
MIHOOLGA_00838 2.2e-202 yheB S Belongs to the UPF0754 family
MIHOOLGA_00839 2.6e-213 yheC HJ YheC/D like ATP-grasp
MIHOOLGA_00840 1.4e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MIHOOLGA_00841 1.3e-36 yheE S Family of unknown function (DUF5342)
MIHOOLGA_00842 6.3e-28 sspB S spore protein
MIHOOLGA_00843 7.1e-107 yheG GM NAD(P)H-binding
MIHOOLGA_00844 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIHOOLGA_00845 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIHOOLGA_00846 1.4e-82 nhaX T Belongs to the universal stress protein A family
MIHOOLGA_00847 1.2e-231 nhaC C Na H antiporter
MIHOOLGA_00848 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MIHOOLGA_00849 1.7e-151 yheN G deacetylase
MIHOOLGA_00850 1.3e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MIHOOLGA_00851 3.1e-201 yhdY M Mechanosensitive ion channel
MIHOOLGA_00853 2e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIHOOLGA_00854 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIHOOLGA_00855 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIHOOLGA_00856 2.3e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MIHOOLGA_00857 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
MIHOOLGA_00858 4.1e-74 cueR K transcriptional
MIHOOLGA_00859 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIHOOLGA_00860 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MIHOOLGA_00861 1.5e-191 yhdN C Aldo keto reductase
MIHOOLGA_00862 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_00863 6.6e-201 yhdL S Sigma factor regulator N-terminal
MIHOOLGA_00864 8.1e-45 yhdK S Sigma-M inhibitor protein
MIHOOLGA_00865 2.2e-75 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_00866 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_00867 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIHOOLGA_00868 3.4e-250 yhdG E amino acid
MIHOOLGA_00869 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_00870 2.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
MIHOOLGA_00871 3.8e-162 citR K Transcriptional regulator
MIHOOLGA_00872 5.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIHOOLGA_00873 1.6e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MIHOOLGA_00874 2.1e-276 ycgB S Stage V sporulation protein R
MIHOOLGA_00875 8.1e-237 ygxB M Conserved TM helix
MIHOOLGA_00876 1e-75 nsrR K Transcriptional regulator
MIHOOLGA_00877 2.9e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIHOOLGA_00878 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MIHOOLGA_00879 1.2e-38 yhdB S YhdB-like protein
MIHOOLGA_00880 1.9e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MIHOOLGA_00881 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_00882 2.7e-213 yhcY 2.7.13.3 T Histidine kinase
MIHOOLGA_00883 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MIHOOLGA_00884 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MIHOOLGA_00885 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIHOOLGA_00886 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MIHOOLGA_00887 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MIHOOLGA_00888 1.2e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIHOOLGA_00889 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIHOOLGA_00890 1.3e-119 yhcW 5.4.2.6 S hydrolase
MIHOOLGA_00891 9.9e-68 yhcV S COG0517 FOG CBS domain
MIHOOLGA_00892 9.3e-68 yhcU S Family of unknown function (DUF5365)
MIHOOLGA_00893 3.9e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIHOOLGA_00894 4.6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MIHOOLGA_00895 6e-192 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MIHOOLGA_00896 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MIHOOLGA_00897 2e-99 yhcQ M Spore coat protein
MIHOOLGA_00898 7.3e-167 yhcP
MIHOOLGA_00899 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIHOOLGA_00900 1.9e-40 yhcM
MIHOOLGA_00901 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIHOOLGA_00902 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MIHOOLGA_00903 2.4e-150 metQ M Belongs to the nlpA lipoprotein family
MIHOOLGA_00904 1e-30 cspB K Cold-shock protein
MIHOOLGA_00905 6.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIHOOLGA_00906 8.5e-165 yhcH V ABC transporter, ATP-binding protein
MIHOOLGA_00907 4e-122 yhcG V ABC transporter, ATP-binding protein
MIHOOLGA_00908 6.6e-60 yhcF K Transcriptional regulator
MIHOOLGA_00909 2e-55
MIHOOLGA_00910 2.8e-37 yhcC
MIHOOLGA_00911 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MIHOOLGA_00912 2.9e-269 yhcA EGP Major facilitator Superfamily
MIHOOLGA_00913 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MIHOOLGA_00914 2.2e-76 yhbI K DNA-binding transcription factor activity
MIHOOLGA_00915 2.5e-225 yhbH S Belongs to the UPF0229 family
MIHOOLGA_00916 0.0 prkA T Ser protein kinase
MIHOOLGA_00917 4.7e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MIHOOLGA_00918 3e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MIHOOLGA_00919 2.1e-109 yhbD K Protein of unknown function (DUF4004)
MIHOOLGA_00920 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIHOOLGA_00921 4.8e-176 yhbB S Putative amidase domain
MIHOOLGA_00922 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIHOOLGA_00923 3.9e-113 yhzB S B3/4 domain
MIHOOLGA_00925 4.4e-29 K Transcriptional regulator
MIHOOLGA_00926 4.1e-78 ygaO
MIHOOLGA_00927 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIHOOLGA_00929 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MIHOOLGA_00930 9.4e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIHOOLGA_00931 8.1e-169 ssuA M Sulfonate ABC transporter
MIHOOLGA_00932 4.8e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MIHOOLGA_00933 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIHOOLGA_00935 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIHOOLGA_00936 5.5e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MIHOOLGA_00937 1.2e-26
MIHOOLGA_00938 1.3e-142 spo0M S COG4326 Sporulation control protein
MIHOOLGA_00942 2e-08
MIHOOLGA_00950 7.8e-08
MIHOOLGA_00955 3e-69 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_00956 5.7e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MIHOOLGA_00957 2.3e-192 yoxA 5.1.3.3 G Aldose 1-epimerase
MIHOOLGA_00958 5.1e-246 yoeA V MATE efflux family protein
MIHOOLGA_00959 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
MIHOOLGA_00961 2.9e-96 L Integrase
MIHOOLGA_00962 6.7e-34 yoeD G Helix-turn-helix domain
MIHOOLGA_00963 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MIHOOLGA_00964 1.7e-154 gltR1 K Transcriptional regulator
MIHOOLGA_00965 1.2e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MIHOOLGA_00966 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MIHOOLGA_00967 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MIHOOLGA_00968 7.8e-155 gltC K Transcriptional regulator
MIHOOLGA_00969 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIHOOLGA_00970 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIHOOLGA_00971 3.3e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MIHOOLGA_00972 2e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_00973 9.2e-39 yoxC S Bacterial protein of unknown function (DUF948)
MIHOOLGA_00974 1.7e-52 yoxB
MIHOOLGA_00975 9.2e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIHOOLGA_00976 6.4e-126 V ABC-2 family transporter protein
MIHOOLGA_00977 9.8e-95 V ABC-2 family transporter protein
MIHOOLGA_00978 5.3e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
MIHOOLGA_00979 3.3e-79 hpr K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_00980 1.3e-232 yoaB EGP Major facilitator Superfamily
MIHOOLGA_00981 1.6e-274 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MIHOOLGA_00982 8.7e-179 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIHOOLGA_00983 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIHOOLGA_00984 3.6e-32 yoaF
MIHOOLGA_00985 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
MIHOOLGA_00986 7e-14
MIHOOLGA_00987 1.5e-38 S Protein of unknown function (DUF4025)
MIHOOLGA_00988 3.8e-179 mcpU NT methyl-accepting chemotaxis protein
MIHOOLGA_00989 1.1e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MIHOOLGA_00990 2.1e-131 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MIHOOLGA_00991 2.3e-111 yoaK S Membrane
MIHOOLGA_00992 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MIHOOLGA_00993 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
MIHOOLGA_00996 6.2e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MIHOOLGA_00998 1e-144 yoaP 3.1.3.18 K YoaP-like
MIHOOLGA_00999 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MIHOOLGA_01001 1.3e-87
MIHOOLGA_01002 2.1e-171 yoaR V vancomycin resistance protein
MIHOOLGA_01003 6.2e-74 yoaS S Protein of unknown function (DUF2975)
MIHOOLGA_01004 4.4e-30 yozG K Transcriptional regulator
MIHOOLGA_01005 1.6e-148 yoaT S Protein of unknown function (DUF817)
MIHOOLGA_01006 7.3e-158 yoaU K LysR substrate binding domain
MIHOOLGA_01007 1.6e-157 yijE EG EamA-like transporter family
MIHOOLGA_01008 1.6e-76 yoaW
MIHOOLGA_01009 3.6e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MIHOOLGA_01010 1.2e-166 bla 3.5.2.6 V beta-lactamase
MIHOOLGA_01013 6.8e-240 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MIHOOLGA_01014 8e-200 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MIHOOLGA_01015 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MIHOOLGA_01016 8.8e-37 S TM2 domain
MIHOOLGA_01018 1.8e-21
MIHOOLGA_01023 4.2e-58 J tRNA cytidylyltransferase activity
MIHOOLGA_01024 9.5e-45 yoaW
MIHOOLGA_01025 1.5e-09 ywlA S Uncharacterised protein family (UPF0715)
MIHOOLGA_01027 4.5e-76
MIHOOLGA_01028 1.3e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
MIHOOLGA_01029 1.4e-24 yoqW S Belongs to the SOS response-associated peptidase family
MIHOOLGA_01031 1.8e-87 S response regulator aspartate phosphatase
MIHOOLGA_01033 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIHOOLGA_01034 3.3e-22 Q Methyltransferase
MIHOOLGA_01035 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
MIHOOLGA_01036 2e-32 Q Methyltransferase domain
MIHOOLGA_01037 5.5e-26 G Major Facilitator Superfamily
MIHOOLGA_01038 3e-229 S impB/mucB/samB family C-terminal domain
MIHOOLGA_01039 8.2e-20 S YolD-like protein
MIHOOLGA_01041 1.3e-84 J Acetyltransferase (GNAT) domain
MIHOOLGA_01042 1.8e-99 yokK S SMI1 / KNR4 family
MIHOOLGA_01043 8.8e-78 S SMI1-KNR4 cell-wall
MIHOOLGA_01044 6.7e-86 S SMI1-KNR4 cell-wall
MIHOOLGA_01045 5.1e-307 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MIHOOLGA_01046 8.5e-91 yokH G SMI1 / KNR4 family
MIHOOLGA_01047 1.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MIHOOLGA_01048 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MIHOOLGA_01049 5.5e-135 yobQ K helix_turn_helix, arabinose operon control protein
MIHOOLGA_01050 2e-140 yobR 2.3.1.1 J FR47-like protein
MIHOOLGA_01051 3.3e-98 yobS K Transcriptional regulator
MIHOOLGA_01052 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MIHOOLGA_01053 2.4e-86 yobU K Bacterial transcription activator, effector binding domain
MIHOOLGA_01054 2.4e-170 yobV K WYL domain
MIHOOLGA_01055 5.3e-90 yobW
MIHOOLGA_01056 8.4e-51 czrA K transcriptional
MIHOOLGA_01057 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MIHOOLGA_01058 1.5e-92 yozB S membrane
MIHOOLGA_01059 3.6e-140
MIHOOLGA_01060 2.5e-94 yocC
MIHOOLGA_01061 5.1e-184 yocD 3.4.17.13 V peptidase S66
MIHOOLGA_01062 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MIHOOLGA_01063 7.1e-198 desK 2.7.13.3 T Histidine kinase
MIHOOLGA_01064 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_01065 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MIHOOLGA_01066 0.0 recQ 3.6.4.12 L DNA helicase
MIHOOLGA_01067 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIHOOLGA_01068 5.7e-83 dksA T general stress protein
MIHOOLGA_01069 2.1e-52 yocL
MIHOOLGA_01070 2e-30
MIHOOLGA_01071 1.8e-86 yocM O Belongs to the small heat shock protein (HSP20) family
MIHOOLGA_01072 1.1e-40 yozN
MIHOOLGA_01073 1.9e-36 yocN
MIHOOLGA_01074 4.2e-56 yozO S Bacterial PH domain
MIHOOLGA_01075 2.7e-31 yozC
MIHOOLGA_01076 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MIHOOLGA_01077 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MIHOOLGA_01078 6e-165 sodA 1.15.1.1 P Superoxide dismutase
MIHOOLGA_01079 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIHOOLGA_01080 5.1e-168 yocS S -transporter
MIHOOLGA_01081 7.7e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MIHOOLGA_01082 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MIHOOLGA_01083 0.0 yojO P Von Willebrand factor
MIHOOLGA_01084 3.2e-161 yojN S ATPase family associated with various cellular activities (AAA)
MIHOOLGA_01085 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIHOOLGA_01086 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MIHOOLGA_01087 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MIHOOLGA_01088 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MIHOOLGA_01090 5.2e-243 norM V Multidrug efflux pump
MIHOOLGA_01091 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIHOOLGA_01092 2.1e-125 yojG S deacetylase
MIHOOLGA_01093 2.2e-60 yojF S Protein of unknown function (DUF1806)
MIHOOLGA_01094 1.5e-43
MIHOOLGA_01095 3.6e-160 rarD S -transporter
MIHOOLGA_01096 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
MIHOOLGA_01097 3.4e-09
MIHOOLGA_01098 3e-174 gntP EG COG2610 H gluconate symporter and related permeases
MIHOOLGA_01099 5.3e-28 gntT EG COG2610 H gluconate symporter and related permeases
MIHOOLGA_01100 8e-64 yodA S tautomerase
MIHOOLGA_01101 4.4e-55 yodB K transcriptional
MIHOOLGA_01102 4.8e-108 yodC C nitroreductase
MIHOOLGA_01103 1.3e-110 mhqD S Carboxylesterase
MIHOOLGA_01104 1.7e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
MIHOOLGA_01105 6.2e-28 S Protein of unknown function (DUF3311)
MIHOOLGA_01106 6.6e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIHOOLGA_01107 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MIHOOLGA_01108 2.8e-128 yodH Q Methyltransferase
MIHOOLGA_01109 5.2e-24 yodI
MIHOOLGA_01110 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MIHOOLGA_01111 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MIHOOLGA_01112 5.3e-09
MIHOOLGA_01113 3.6e-54 yodL S YodL-like
MIHOOLGA_01114 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
MIHOOLGA_01115 2.8e-24 yozD S YozD-like protein
MIHOOLGA_01117 6e-123 yodN
MIHOOLGA_01118 1.4e-36 yozE S Belongs to the UPF0346 family
MIHOOLGA_01119 2.9e-47 yokU S YokU-like protein, putative antitoxin
MIHOOLGA_01120 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
MIHOOLGA_01121 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MIHOOLGA_01122 4.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
MIHOOLGA_01123 2.3e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MIHOOLGA_01124 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIHOOLGA_01125 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIHOOLGA_01127 1.2e-143 yiiD K acetyltransferase
MIHOOLGA_01128 7.2e-255 cgeD M maturation of the outermost layer of the spore
MIHOOLGA_01129 5.9e-38 cgeC
MIHOOLGA_01130 1.2e-65 cgeA
MIHOOLGA_01131 5.3e-186 cgeB S Spore maturation protein
MIHOOLGA_01132 1.3e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MIHOOLGA_01133 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
MIHOOLGA_01134 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MIHOOLGA_01135 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIHOOLGA_01136 1.6e-70 ypoP K transcriptional
MIHOOLGA_01137 2.2e-222 mepA V MATE efflux family protein
MIHOOLGA_01138 1.6e-28 ypmT S Uncharacterized ympT
MIHOOLGA_01139 1.1e-98 ypmS S protein conserved in bacteria
MIHOOLGA_01140 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MIHOOLGA_01141 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MIHOOLGA_01142 8.9e-40 ypmP S Protein of unknown function (DUF2535)
MIHOOLGA_01143 1.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIHOOLGA_01144 5.2e-184 pspF K Transcriptional regulator
MIHOOLGA_01145 4.2e-110 hlyIII S protein, Hemolysin III
MIHOOLGA_01146 2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MIHOOLGA_01147 2.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MIHOOLGA_01148 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIHOOLGA_01149 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MIHOOLGA_01150 7.8e-114 ypjP S YpjP-like protein
MIHOOLGA_01151 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MIHOOLGA_01152 1.7e-75 yphP S Belongs to the UPF0403 family
MIHOOLGA_01153 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MIHOOLGA_01154 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MIHOOLGA_01155 8.7e-105 ypgQ S phosphohydrolase
MIHOOLGA_01156 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MIHOOLGA_01157 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIHOOLGA_01158 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MIHOOLGA_01159 7.9e-31 cspD K Cold-shock protein
MIHOOLGA_01160 3.8e-16 degR
MIHOOLGA_01161 8.1e-31 S Protein of unknown function (DUF2564)
MIHOOLGA_01162 2.6e-27 ypeQ S Zinc-finger
MIHOOLGA_01163 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MIHOOLGA_01164 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIHOOLGA_01165 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
MIHOOLGA_01167 1.7e-165 polA 2.7.7.7 L 5'3' exonuclease
MIHOOLGA_01168 2e-07
MIHOOLGA_01169 5.5e-37 ypbS S Protein of unknown function (DUF2533)
MIHOOLGA_01170 0.0 ypbR S Dynamin family
MIHOOLGA_01172 1.5e-86 ypbQ S protein conserved in bacteria
MIHOOLGA_01173 2.8e-207 bcsA Q Naringenin-chalcone synthase
MIHOOLGA_01174 3.8e-227 pbuX F xanthine
MIHOOLGA_01175 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIHOOLGA_01176 1.9e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MIHOOLGA_01177 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MIHOOLGA_01178 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MIHOOLGA_01179 3.5e-185 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MIHOOLGA_01180 1.5e-186 ptxS K transcriptional
MIHOOLGA_01181 1.4e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MIHOOLGA_01182 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_01183 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MIHOOLGA_01185 2.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MIHOOLGA_01186 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MIHOOLGA_01187 1.4e-87 ypsA S Belongs to the UPF0398 family
MIHOOLGA_01188 5.6e-236 yprB L RNase_H superfamily
MIHOOLGA_01189 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MIHOOLGA_01190 7.9e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MIHOOLGA_01191 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MIHOOLGA_01192 1e-47 yppG S YppG-like protein
MIHOOLGA_01194 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
MIHOOLGA_01197 2e-185 yppC S Protein of unknown function (DUF2515)
MIHOOLGA_01198 1e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MIHOOLGA_01199 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MIHOOLGA_01200 2e-91 ypoC
MIHOOLGA_01201 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIHOOLGA_01202 1.3e-128 dnaD L DNA replication protein DnaD
MIHOOLGA_01203 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MIHOOLGA_01204 7.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MIHOOLGA_01205 2.2e-79 ypmB S protein conserved in bacteria
MIHOOLGA_01206 1.9e-22 ypmA S Protein of unknown function (DUF4264)
MIHOOLGA_01207 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MIHOOLGA_01208 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MIHOOLGA_01209 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MIHOOLGA_01210 3.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MIHOOLGA_01211 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MIHOOLGA_01212 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MIHOOLGA_01213 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MIHOOLGA_01214 1.7e-128 bshB1 S proteins, LmbE homologs
MIHOOLGA_01215 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MIHOOLGA_01216 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIHOOLGA_01217 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MIHOOLGA_01218 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MIHOOLGA_01219 3.9e-142 ypjB S sporulation protein
MIHOOLGA_01220 8.9e-99 ypjA S membrane
MIHOOLGA_01221 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MIHOOLGA_01222 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MIHOOLGA_01223 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MIHOOLGA_01224 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MIHOOLGA_01225 2.8e-99 ypiB S Belongs to the UPF0302 family
MIHOOLGA_01226 7.7e-233 S COG0457 FOG TPR repeat
MIHOOLGA_01227 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIHOOLGA_01228 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MIHOOLGA_01229 3.9e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIHOOLGA_01230 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIHOOLGA_01231 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIHOOLGA_01232 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MIHOOLGA_01233 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MIHOOLGA_01234 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIHOOLGA_01235 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIHOOLGA_01236 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MIHOOLGA_01237 6.9e-206 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIHOOLGA_01238 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIHOOLGA_01239 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MIHOOLGA_01240 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MIHOOLGA_01241 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIHOOLGA_01242 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MIHOOLGA_01243 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MIHOOLGA_01244 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MIHOOLGA_01245 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MIHOOLGA_01246 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MIHOOLGA_01247 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MIHOOLGA_01248 6e-137 yphF
MIHOOLGA_01249 2e-18 yphE S Protein of unknown function (DUF2768)
MIHOOLGA_01250 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MIHOOLGA_01251 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MIHOOLGA_01252 2.3e-27 ypzH
MIHOOLGA_01253 3.3e-161 seaA S YIEGIA protein
MIHOOLGA_01254 6.7e-102 yphA
MIHOOLGA_01255 1e-07 S YpzI-like protein
MIHOOLGA_01256 3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MIHOOLGA_01257 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MIHOOLGA_01258 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MIHOOLGA_01259 1.8e-23 S Family of unknown function (DUF5359)
MIHOOLGA_01260 1e-111 ypfA M Flagellar protein YcgR
MIHOOLGA_01261 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MIHOOLGA_01262 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MIHOOLGA_01263 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MIHOOLGA_01264 4.8e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MIHOOLGA_01265 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIHOOLGA_01266 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIHOOLGA_01267 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MIHOOLGA_01268 3.7e-81 ypbF S Protein of unknown function (DUF2663)
MIHOOLGA_01269 2.6e-76 ypbE M Lysin motif
MIHOOLGA_01270 2.2e-100 ypbD S metal-dependent membrane protease
MIHOOLGA_01271 9.2e-286 recQ 3.6.4.12 L DNA helicase
MIHOOLGA_01272 1.2e-199 ypbB 5.1.3.1 S protein conserved in bacteria
MIHOOLGA_01273 4.7e-41 fer C Ferredoxin
MIHOOLGA_01274 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MIHOOLGA_01275 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIHOOLGA_01276 1.8e-131 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MIHOOLGA_01277 1.4e-185 rsiX
MIHOOLGA_01278 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_01279 0.0 resE 2.7.13.3 T Histidine kinase
MIHOOLGA_01280 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_01281 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MIHOOLGA_01282 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MIHOOLGA_01283 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MIHOOLGA_01284 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIHOOLGA_01285 5.4e-87 spmB S Spore maturation protein
MIHOOLGA_01286 3.5e-103 spmA S Spore maturation protein
MIHOOLGA_01287 2e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MIHOOLGA_01288 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MIHOOLGA_01289 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIHOOLGA_01290 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIHOOLGA_01291 1.6e-91 ypuF S Domain of unknown function (DUF309)
MIHOOLGA_01292 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_01293 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MIHOOLGA_01294 4.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MIHOOLGA_01295 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
MIHOOLGA_01296 6.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIHOOLGA_01297 7.8e-55 ypuD
MIHOOLGA_01298 3.9e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIHOOLGA_01299 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MIHOOLGA_01300 5.9e-15 S SNARE associated Golgi protein
MIHOOLGA_01301 5.2e-08 eaeH M Domain of Unknown Function (DUF1259)
MIHOOLGA_01303 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIHOOLGA_01304 3.6e-149 ypuA S Secreted protein
MIHOOLGA_01305 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIHOOLGA_01306 1.4e-273 spoVAF EG Stage V sporulation protein AF
MIHOOLGA_01307 1.4e-110 spoVAEA S stage V sporulation protein
MIHOOLGA_01308 2.2e-57 spoVAEB S stage V sporulation protein
MIHOOLGA_01309 9e-192 spoVAD I Stage V sporulation protein AD
MIHOOLGA_01310 1.5e-77 spoVAC S stage V sporulation protein AC
MIHOOLGA_01311 1e-67 spoVAB S Stage V sporulation protein AB
MIHOOLGA_01312 9.6e-112 spoVAA S Stage V sporulation protein AA
MIHOOLGA_01313 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_01314 8.7e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MIHOOLGA_01315 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MIHOOLGA_01316 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MIHOOLGA_01317 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MIHOOLGA_01318 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MIHOOLGA_01319 2.6e-166 xerD L recombinase XerD
MIHOOLGA_01320 3.2e-36 S Protein of unknown function (DUF4227)
MIHOOLGA_01321 2.4e-80 fur P Belongs to the Fur family
MIHOOLGA_01322 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MIHOOLGA_01323 3.2e-30 yqkK
MIHOOLGA_01324 5.5e-242 mleA 1.1.1.38 C malic enzyme
MIHOOLGA_01325 3.1e-235 mleN C Na H antiporter
MIHOOLGA_01326 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MIHOOLGA_01327 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MIHOOLGA_01328 4.5e-58 ansR K Transcriptional regulator
MIHOOLGA_01329 1.4e-220 yqxK 3.6.4.12 L DNA helicase
MIHOOLGA_01330 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MIHOOLGA_01332 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MIHOOLGA_01333 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MIHOOLGA_01334 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MIHOOLGA_01335 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MIHOOLGA_01336 2.8e-54 yqkB S Belongs to the HesB IscA family
MIHOOLGA_01337 5.4e-192 yqkA K GrpB protein
MIHOOLGA_01338 8.9e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MIHOOLGA_01339 1.1e-86 yqjY K acetyltransferase
MIHOOLGA_01340 1.7e-49 S YolD-like protein
MIHOOLGA_01341 6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIHOOLGA_01343 2.2e-224 yqjV G Major Facilitator Superfamily
MIHOOLGA_01345 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_01346 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MIHOOLGA_01347 3.8e-262 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MIHOOLGA_01348 1.7e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_01349 1.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MIHOOLGA_01350 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIHOOLGA_01351 0.0 rocB E arginine degradation protein
MIHOOLGA_01352 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MIHOOLGA_01353 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MIHOOLGA_01354 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MIHOOLGA_01355 1.1e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MIHOOLGA_01356 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIHOOLGA_01357 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIHOOLGA_01358 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIHOOLGA_01359 4.5e-24 yqzJ
MIHOOLGA_01360 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIHOOLGA_01361 2.9e-139 yqjF S Uncharacterized conserved protein (COG2071)
MIHOOLGA_01362 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MIHOOLGA_01363 4.1e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIHOOLGA_01364 1.9e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MIHOOLGA_01366 1.4e-98 yqjB S protein conserved in bacteria
MIHOOLGA_01367 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MIHOOLGA_01368 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIHOOLGA_01369 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MIHOOLGA_01370 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MIHOOLGA_01371 9.3e-77 yqiW S Belongs to the UPF0403 family
MIHOOLGA_01372 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIHOOLGA_01373 3e-207 norA EGP Major facilitator Superfamily
MIHOOLGA_01374 7.5e-152 bmrR K helix_turn_helix, mercury resistance
MIHOOLGA_01375 4.1e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIHOOLGA_01376 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIHOOLGA_01377 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIHOOLGA_01378 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIHOOLGA_01379 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MIHOOLGA_01380 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIHOOLGA_01381 1.1e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MIHOOLGA_01382 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MIHOOLGA_01383 4e-34 yqzF S Protein of unknown function (DUF2627)
MIHOOLGA_01384 2.1e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MIHOOLGA_01385 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MIHOOLGA_01386 1.7e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MIHOOLGA_01387 1.8e-212 mmgC I acyl-CoA dehydrogenase
MIHOOLGA_01388 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
MIHOOLGA_01389 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
MIHOOLGA_01390 8.9e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIHOOLGA_01391 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MIHOOLGA_01392 6e-27
MIHOOLGA_01393 9.5e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MIHOOLGA_01395 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MIHOOLGA_01396 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MIHOOLGA_01397 6.5e-307 recN L May be involved in recombinational repair of damaged DNA
MIHOOLGA_01398 1.7e-78 argR K Regulates arginine biosynthesis genes
MIHOOLGA_01399 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MIHOOLGA_01400 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIHOOLGA_01401 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIHOOLGA_01402 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIHOOLGA_01403 4.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIHOOLGA_01404 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIHOOLGA_01405 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIHOOLGA_01406 2.1e-67 yqhY S protein conserved in bacteria
MIHOOLGA_01407 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MIHOOLGA_01408 2.6e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MIHOOLGA_01409 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MIHOOLGA_01410 3.4e-102 spoIIIAG S stage III sporulation protein AG
MIHOOLGA_01411 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MIHOOLGA_01412 3.8e-197 spoIIIAE S stage III sporulation protein AE
MIHOOLGA_01413 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MIHOOLGA_01414 7.6e-29 spoIIIAC S stage III sporulation protein AC
MIHOOLGA_01415 1.1e-84 spoIIIAB S Stage III sporulation protein
MIHOOLGA_01416 6.8e-170 spoIIIAA S stage III sporulation protein AA
MIHOOLGA_01417 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MIHOOLGA_01418 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIHOOLGA_01419 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIHOOLGA_01420 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MIHOOLGA_01421 2.3e-93 yqhR S Conserved membrane protein YqhR
MIHOOLGA_01422 8e-174 yqhQ S Protein of unknown function (DUF1385)
MIHOOLGA_01423 2.2e-61 yqhP
MIHOOLGA_01424 4.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
MIHOOLGA_01425 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MIHOOLGA_01426 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MIHOOLGA_01427 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MIHOOLGA_01428 1e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIHOOLGA_01429 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIHOOLGA_01430 1.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MIHOOLGA_01431 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIHOOLGA_01432 2.1e-151 yqhG S Bacterial protein YqhG of unknown function
MIHOOLGA_01433 1.2e-24 sinI S Anti-repressor SinI
MIHOOLGA_01434 1e-54 sinR K transcriptional
MIHOOLGA_01435 2.5e-141 tasA S Cell division protein FtsN
MIHOOLGA_01436 1.9e-58 sipW 3.4.21.89 U Signal peptidase
MIHOOLGA_01437 1.7e-110 yqxM
MIHOOLGA_01438 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MIHOOLGA_01439 1.4e-26 yqzE S YqzE-like protein
MIHOOLGA_01440 2.6e-43 S ComG operon protein 7
MIHOOLGA_01441 2.2e-34 comGF U Putative Competence protein ComGF
MIHOOLGA_01442 2.2e-57 comGE
MIHOOLGA_01443 1.2e-68 gspH NU protein transport across the cell outer membrane
MIHOOLGA_01444 1.4e-47 comGC U Required for transformation and DNA binding
MIHOOLGA_01445 4.4e-170 comGB NU COG1459 Type II secretory pathway, component PulF
MIHOOLGA_01446 8.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIHOOLGA_01448 7.2e-175 corA P Mg2 transporter protein
MIHOOLGA_01449 6.7e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIHOOLGA_01450 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIHOOLGA_01452 2.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
MIHOOLGA_01453 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MIHOOLGA_01454 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MIHOOLGA_01455 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MIHOOLGA_01456 2.6e-49 yqgV S Thiamine-binding protein
MIHOOLGA_01457 4.6e-199 yqgU
MIHOOLGA_01458 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MIHOOLGA_01459 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIHOOLGA_01460 5.2e-181 glcK 2.7.1.2 G Glucokinase
MIHOOLGA_01461 4.3e-33 yqgQ S Protein conserved in bacteria
MIHOOLGA_01462 1.2e-261 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MIHOOLGA_01463 2.5e-09 yqgO
MIHOOLGA_01464 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIHOOLGA_01465 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MIHOOLGA_01466 1.7e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MIHOOLGA_01468 9.2e-51 yqzD
MIHOOLGA_01469 7e-75 yqzC S YceG-like family
MIHOOLGA_01470 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIHOOLGA_01471 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIHOOLGA_01472 4.4e-158 pstA P Phosphate transport system permease
MIHOOLGA_01473 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MIHOOLGA_01474 3.4e-150 pstS P Phosphate
MIHOOLGA_01475 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MIHOOLGA_01476 2.5e-231 yqgE EGP Major facilitator superfamily
MIHOOLGA_01477 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MIHOOLGA_01478 4e-73 yqgC S protein conserved in bacteria
MIHOOLGA_01479 3.9e-131 yqgB S Protein of unknown function (DUF1189)
MIHOOLGA_01480 5.2e-47 yqfZ M LysM domain
MIHOOLGA_01481 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIHOOLGA_01482 4.3e-62 yqfX S membrane
MIHOOLGA_01483 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MIHOOLGA_01484 1.9e-77 zur P Belongs to the Fur family
MIHOOLGA_01485 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIHOOLGA_01486 7.9e-36 yqfT S Protein of unknown function (DUF2624)
MIHOOLGA_01487 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MIHOOLGA_01488 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MIHOOLGA_01489 3.5e-12 yqfQ S YqfQ-like protein
MIHOOLGA_01490 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIHOOLGA_01491 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIHOOLGA_01492 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MIHOOLGA_01493 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MIHOOLGA_01494 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIHOOLGA_01495 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIHOOLGA_01496 4.5e-88 yaiI S Belongs to the UPF0178 family
MIHOOLGA_01497 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MIHOOLGA_01498 4.5e-112 ccpN K CBS domain
MIHOOLGA_01499 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MIHOOLGA_01500 7.4e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MIHOOLGA_01501 8.2e-145 recO L Involved in DNA repair and RecF pathway recombination
MIHOOLGA_01502 8.4e-19 S YqzL-like protein
MIHOOLGA_01503 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIHOOLGA_01504 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MIHOOLGA_01505 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MIHOOLGA_01506 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIHOOLGA_01507 0.0 yqfF S membrane-associated HD superfamily hydrolase
MIHOOLGA_01509 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MIHOOLGA_01510 1.1e-183 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MIHOOLGA_01511 2.7e-45 yqfC S sporulation protein YqfC
MIHOOLGA_01512 6e-25 yqfB
MIHOOLGA_01513 3.7e-121 yqfA S UPF0365 protein
MIHOOLGA_01514 1.9e-226 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MIHOOLGA_01515 2.5e-61 yqeY S Yqey-like protein
MIHOOLGA_01516 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MIHOOLGA_01517 3.4e-156 yqeW P COG1283 Na phosphate symporter
MIHOOLGA_01518 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MIHOOLGA_01519 6.7e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIHOOLGA_01520 5.4e-175 prmA J Methylates ribosomal protein L11
MIHOOLGA_01521 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIHOOLGA_01522 0.0 dnaK O Heat shock 70 kDa protein
MIHOOLGA_01523 1.6e-65 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIHOOLGA_01524 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIHOOLGA_01525 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MIHOOLGA_01526 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIHOOLGA_01527 8e-52 yqxA S Protein of unknown function (DUF3679)
MIHOOLGA_01528 1.5e-222 spoIIP M stage II sporulation protein P
MIHOOLGA_01529 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MIHOOLGA_01530 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MIHOOLGA_01531 2.1e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
MIHOOLGA_01532 4.1e-15 S YqzM-like protein
MIHOOLGA_01533 0.0 comEC S Competence protein ComEC
MIHOOLGA_01534 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MIHOOLGA_01535 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MIHOOLGA_01536 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIHOOLGA_01537 5.5e-138 yqeM Q Methyltransferase
MIHOOLGA_01538 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIHOOLGA_01539 6.2e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MIHOOLGA_01540 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIHOOLGA_01541 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MIHOOLGA_01542 1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MIHOOLGA_01543 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MIHOOLGA_01544 5.3e-95 yqeG S hydrolase of the HAD superfamily
MIHOOLGA_01546 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MIHOOLGA_01547 8.3e-134 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIHOOLGA_01548 3.3e-104 yqeD S SNARE associated Golgi protein
MIHOOLGA_01549 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MIHOOLGA_01550 2.3e-133 yqeB
MIHOOLGA_01551 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
MIHOOLGA_01552 2.8e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_01553 1.8e-62 napB K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_01554 1.4e-219 yfjF U Belongs to the major facilitator superfamily
MIHOOLGA_01555 2.1e-277 cisA2 L Recombinase
MIHOOLGA_01556 1.5e-105 K Transcriptional regulator
MIHOOLGA_01557 1.3e-123 yecA E amino acid
MIHOOLGA_01559 3.4e-131 S Aspartate phosphatase response regulator
MIHOOLGA_01561 2.7e-62
MIHOOLGA_01562 1e-181 yaaC S YaaC-like Protein
MIHOOLGA_01563 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIHOOLGA_01564 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MIHOOLGA_01565 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIHOOLGA_01566 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIHOOLGA_01567 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIHOOLGA_01568 1.3e-09
MIHOOLGA_01569 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MIHOOLGA_01570 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MIHOOLGA_01571 1.1e-213 yaaH M Glycoside Hydrolase Family
MIHOOLGA_01572 9.9e-29 yaaI Q COG1335 Amidases related to nicotinamidase
MIHOOLGA_01573 9.5e-45 yaaI Q COG1335 Amidases related to nicotinamidase
MIHOOLGA_01574 2.5e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIHOOLGA_01575 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIHOOLGA_01576 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MIHOOLGA_01577 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIHOOLGA_01578 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MIHOOLGA_01579 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
MIHOOLGA_01580 8.2e-165 ygxA S Nucleotidyltransferase-like
MIHOOLGA_01581 2.1e-55 ygzB S UPF0295 protein
MIHOOLGA_01582 4e-80 perR P Belongs to the Fur family
MIHOOLGA_01583 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MIHOOLGA_01584 3.1e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIHOOLGA_01585 8.7e-180 ygaE S Membrane
MIHOOLGA_01586 1.8e-301 ygaD V ABC transporter
MIHOOLGA_01587 1.3e-104 ygaC J Belongs to the UPF0374 family
MIHOOLGA_01588 1.5e-37 ygaB S YgaB-like protein
MIHOOLGA_01589 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MIHOOLGA_01590 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_01591 6.9e-36 yfhS
MIHOOLGA_01592 2.5e-210 mutY L A G-specific
MIHOOLGA_01593 1.2e-185 yfhP S membrane-bound metal-dependent
MIHOOLGA_01594 0.0 yfhO S Bacterial membrane protein YfhO
MIHOOLGA_01595 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_01596 2e-171 yfhM S Alpha beta hydrolase
MIHOOLGA_01597 3.5e-51 yfhL S SdpI/YhfL protein family
MIHOOLGA_01598 1.5e-86 batE T Bacterial SH3 domain homologues
MIHOOLGA_01599 2.9e-44 yfhJ S WVELL protein
MIHOOLGA_01600 6.2e-20 sspK S reproduction
MIHOOLGA_01601 1.1e-209 yfhI EGP Major facilitator Superfamily
MIHOOLGA_01603 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MIHOOLGA_01604 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MIHOOLGA_01605 1.4e-172 yfhF S nucleoside-diphosphate sugar epimerase
MIHOOLGA_01607 2.1e-25 yfhD S YfhD-like protein
MIHOOLGA_01608 3.9e-107 yfhC C nitroreductase
MIHOOLGA_01609 1.3e-165 yfhB 5.3.3.17 S PhzF family
MIHOOLGA_01610 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01611 4.4e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01612 2.4e-181 yfiY P ABC transporter substrate-binding protein
MIHOOLGA_01613 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MIHOOLGA_01614 4.9e-79 yfiV K transcriptional
MIHOOLGA_01615 1.7e-282 yfiU EGP Major facilitator Superfamily
MIHOOLGA_01616 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
MIHOOLGA_01617 9e-218 yfiS EGP Major facilitator Superfamily
MIHOOLGA_01618 7.6e-109 yfiR K Transcriptional regulator
MIHOOLGA_01619 1.2e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MIHOOLGA_01620 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIHOOLGA_01621 8.3e-99 padR K transcriptional
MIHOOLGA_01622 4.9e-202 V COG0842 ABC-type multidrug transport system, permease component
MIHOOLGA_01623 1.8e-207 V ABC-2 family transporter protein
MIHOOLGA_01624 1.4e-167 V ABC transporter, ATP-binding protein
MIHOOLGA_01625 4.6e-112 KT LuxR family transcriptional regulator
MIHOOLGA_01626 1.8e-212 yxjM T Histidine kinase
MIHOOLGA_01628 1.8e-161 yfiE 1.13.11.2 S glyoxalase
MIHOOLGA_01629 9.8e-65 mhqP S DoxX
MIHOOLGA_01630 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIHOOLGA_01631 8.1e-310 yfiB3 V ABC transporter
MIHOOLGA_01632 0.0 yobO M COG5434 Endopolygalacturonase
MIHOOLGA_01633 8.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_01634 1e-139 glvR K Helix-turn-helix domain, rpiR family
MIHOOLGA_01635 1.1e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIHOOLGA_01636 1.9e-14 S Domain of unknown function (DUF5082)
MIHOOLGA_01637 7.8e-13 yxiC S Family of unknown function (DUF5344)
MIHOOLGA_01638 1.8e-74 S LXG domain of WXG superfamily
MIHOOLGA_01640 1.3e-17 S Protein conserved in bacteria
MIHOOLGA_01643 1.1e-44 yfjA S Belongs to the WXG100 family
MIHOOLGA_01644 2.3e-189 yfjB
MIHOOLGA_01645 1.5e-143 yfjC
MIHOOLGA_01646 1.8e-101 yfjD S Family of unknown function (DUF5381)
MIHOOLGA_01647 7.2e-79 S Family of unknown function (DUF5381)
MIHOOLGA_01648 4e-56 yfjF S UPF0060 membrane protein
MIHOOLGA_01649 1.2e-25 sspH S Belongs to the SspH family
MIHOOLGA_01650 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MIHOOLGA_01651 3.1e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIHOOLGA_01652 1.1e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIHOOLGA_01653 1.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIHOOLGA_01654 1.7e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIHOOLGA_01655 6e-30 yfjL
MIHOOLGA_01656 9.6e-85 yfjM S Psort location Cytoplasmic, score
MIHOOLGA_01657 2e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIHOOLGA_01658 3.9e-44 S YfzA-like protein
MIHOOLGA_01659 6.9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIHOOLGA_01660 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIHOOLGA_01661 1.7e-184 corA P Mediates influx of magnesium ions
MIHOOLGA_01662 6.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MIHOOLGA_01663 1.7e-153 pdaA G deacetylase
MIHOOLGA_01664 1.1e-26 yfjT
MIHOOLGA_01665 5.4e-222 yfkA S YfkB-like domain
MIHOOLGA_01666 6e-149 yfkC M Mechanosensitive ion channel
MIHOOLGA_01667 4.5e-146 yfkD S YfkD-like protein
MIHOOLGA_01668 6.1e-183 cax P COG0387 Ca2 H antiporter
MIHOOLGA_01669 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MIHOOLGA_01670 9.7e-144 yihY S Belongs to the UPF0761 family
MIHOOLGA_01671 2.4e-50 yfkI S gas vesicle protein
MIHOOLGA_01672 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIHOOLGA_01673 2.1e-29 yfkK S Belongs to the UPF0435 family
MIHOOLGA_01674 2.2e-205 ydiM EGP Major facilitator Superfamily
MIHOOLGA_01675 1.4e-87 yfkM 1.11.1.6, 3.5.1.124 S protease
MIHOOLGA_01676 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MIHOOLGA_01677 1.1e-124 yfkO C nitroreductase
MIHOOLGA_01678 8.7e-133 treR K transcriptional
MIHOOLGA_01679 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MIHOOLGA_01680 3.2e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_01681 4e-27 yfkQ EG Spore germination protein
MIHOOLGA_01682 2.2e-252 agcS_1 E Sodium alanine symporter
MIHOOLGA_01683 6e-67 yhdN S Domain of unknown function (DUF1992)
MIHOOLGA_01684 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIHOOLGA_01685 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MIHOOLGA_01686 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MIHOOLGA_01687 2.4e-50 yflH S Protein of unknown function (DUF3243)
MIHOOLGA_01688 4.1e-19 yflI
MIHOOLGA_01689 4e-18 yflJ S Protein of unknown function (DUF2639)
MIHOOLGA_01690 9.9e-123 yflK S protein conserved in bacteria
MIHOOLGA_01691 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MIHOOLGA_01692 1.9e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MIHOOLGA_01693 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MIHOOLGA_01694 8.5e-227 citM C Citrate transporter
MIHOOLGA_01695 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
MIHOOLGA_01696 1.4e-116 citT T response regulator
MIHOOLGA_01697 4.8e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIHOOLGA_01698 2.7e-234 yflS P Sodium:sulfate symporter transmembrane region
MIHOOLGA_01699 9.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MIHOOLGA_01700 7.6e-58 yflT S Heat induced stress protein YflT
MIHOOLGA_01701 5.5e-23 S Protein of unknown function (DUF3212)
MIHOOLGA_01702 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MIHOOLGA_01703 5.3e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01704 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01705 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MIHOOLGA_01706 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
MIHOOLGA_01707 3e-75 yfmK 2.3.1.128 K acetyltransferase
MIHOOLGA_01708 7.7e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MIHOOLGA_01709 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIHOOLGA_01710 2.5e-36
MIHOOLGA_01711 1.2e-208 yfmO EGP Major facilitator Superfamily
MIHOOLGA_01712 2.4e-69 yfmP K transcriptional
MIHOOLGA_01713 1.2e-68 yfmQ S Uncharacterised protein from bacillus cereus group
MIHOOLGA_01714 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIHOOLGA_01715 1.1e-113 yfmS NT chemotaxis protein
MIHOOLGA_01716 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIHOOLGA_01717 5.4e-240 yfnA E amino acid
MIHOOLGA_01718 3.6e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MIHOOLGA_01719 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
MIHOOLGA_01720 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
MIHOOLGA_01721 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MIHOOLGA_01722 2.3e-178 yfnF M Nucleotide-diphospho-sugar transferase
MIHOOLGA_01723 3.2e-172 yfnG 4.2.1.45 M dehydratase
MIHOOLGA_01724 3.9e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MIHOOLGA_01725 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIHOOLGA_01726 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MIHOOLGA_01727 3.6e-199 yetN S Protein of unknown function (DUF3900)
MIHOOLGA_01728 1.9e-30 yetM CH FAD binding domain
MIHOOLGA_01729 5.3e-105 yetJ S Belongs to the BI1 family
MIHOOLGA_01730 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MIHOOLGA_01731 3.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIHOOLGA_01732 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_01733 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MIHOOLGA_01734 8.8e-122 yetF S membrane
MIHOOLGA_01735 1.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIHOOLGA_01736 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MIHOOLGA_01737 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MIHOOLGA_01738 1.8e-289 lplA G Bacterial extracellular solute-binding protein
MIHOOLGA_01739 0.0 yetA
MIHOOLGA_01740 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MIHOOLGA_01741 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MIHOOLGA_01742 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MIHOOLGA_01743 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MIHOOLGA_01744 8.8e-113 yesV S Protein of unknown function, DUF624
MIHOOLGA_01745 3e-127 yesU S Domain of unknown function (DUF1961)
MIHOOLGA_01746 2.6e-129 E GDSL-like Lipase/Acylhydrolase
MIHOOLGA_01747 0.0 yesS K Transcriptional regulator
MIHOOLGA_01748 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MIHOOLGA_01749 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
MIHOOLGA_01750 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MIHOOLGA_01751 3.3e-247 yesO G Bacterial extracellular solute-binding protein
MIHOOLGA_01752 5.6e-203 yesN K helix_turn_helix, arabinose operon control protein
MIHOOLGA_01753 0.0 yesM 2.7.13.3 T Histidine kinase
MIHOOLGA_01754 1.2e-101 yesL S Protein of unknown function, DUF624
MIHOOLGA_01756 8.7e-101 yesJ K Acetyltransferase (GNAT) family
MIHOOLGA_01757 5.2e-104 cotJC P Spore Coat
MIHOOLGA_01758 1.5e-45 cotJB S CotJB protein
MIHOOLGA_01759 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
MIHOOLGA_01760 5.3e-145 yesF GM NAD(P)H-binding
MIHOOLGA_01761 9.1e-80 yesE S SnoaL-like domain
MIHOOLGA_01762 1.2e-103 dhaR3 K Transcriptional regulator
MIHOOLGA_01764 9.4e-127 yeeN K transcriptional regulatory protein
MIHOOLGA_01766 1.8e-212 S Tetratricopeptide repeat
MIHOOLGA_01767 1.4e-120 3.4.24.40 CO amine dehydrogenase activity
MIHOOLGA_01768 3.6e-186 yobL S Bacterial EndoU nuclease
MIHOOLGA_01769 1.3e-42 S Immunity protein 22
MIHOOLGA_01770 1.1e-100 S response regulator aspartate phosphatase
MIHOOLGA_01772 1e-302 L DEAD-like helicases superfamily
MIHOOLGA_01773 1.6e-87
MIHOOLGA_01774 5.5e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIHOOLGA_01775 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIHOOLGA_01776 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIHOOLGA_01777 1.3e-146 yerO K Transcriptional regulator
MIHOOLGA_01778 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIHOOLGA_01779 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIHOOLGA_01780 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIHOOLGA_01781 9.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIHOOLGA_01782 2.7e-123 sapB S MgtC SapB transporter
MIHOOLGA_01783 2.8e-193 yerI S homoserine kinase type II (protein kinase fold)
MIHOOLGA_01784 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MIHOOLGA_01785 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIHOOLGA_01786 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MIHOOLGA_01787 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MIHOOLGA_01789 1.5e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MIHOOLGA_01790 4.8e-51 yerC S protein conserved in bacteria
MIHOOLGA_01791 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MIHOOLGA_01792 0.0 yerA 3.5.4.2 F adenine deaminase
MIHOOLGA_01793 1.1e-28 S Protein of unknown function (DUF2892)
MIHOOLGA_01794 7.3e-231 yjeH E Amino acid permease
MIHOOLGA_01795 1e-72 K helix_turn_helix ASNC type
MIHOOLGA_01796 1.7e-232 purD 6.3.4.13 F Belongs to the GARS family
MIHOOLGA_01797 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MIHOOLGA_01798 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIHOOLGA_01799 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MIHOOLGA_01800 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIHOOLGA_01801 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIHOOLGA_01802 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIHOOLGA_01803 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIHOOLGA_01804 4.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MIHOOLGA_01805 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIHOOLGA_01806 1.6e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIHOOLGA_01807 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIHOOLGA_01808 8e-28 yebG S NETI protein
MIHOOLGA_01809 8.9e-93 yebE S UPF0316 protein
MIHOOLGA_01811 2.3e-118 yebC M Membrane
MIHOOLGA_01812 7.8e-212 pbuG S permease
MIHOOLGA_01813 2.1e-250 S Domain of unknown function (DUF4179)
MIHOOLGA_01814 1e-85 K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_01815 7.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MIHOOLGA_01816 0.0 yebA E COG1305 Transglutaminase-like enzymes
MIHOOLGA_01817 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MIHOOLGA_01818 1.7e-176 yeaC S COG0714 MoxR-like ATPases
MIHOOLGA_01819 1.9e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIHOOLGA_01820 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_01821 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MIHOOLGA_01822 3e-176 yeaA S Protein of unknown function (DUF4003)
MIHOOLGA_01823 3.1e-158 ydjP I Alpha/beta hydrolase family
MIHOOLGA_01824 1.4e-34 ydjO S Cold-inducible protein YdjO
MIHOOLGA_01826 5.5e-152 ydjN U Involved in the tonB-independent uptake of proteins
MIHOOLGA_01827 4.5e-64 ydjM M Lytic transglycolase
MIHOOLGA_01828 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MIHOOLGA_01829 3.9e-257 iolT EGP Major facilitator Superfamily
MIHOOLGA_01830 4.7e-196 S Ion transport 2 domain protein
MIHOOLGA_01831 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
MIHOOLGA_01832 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MIHOOLGA_01833 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIHOOLGA_01834 5.6e-113 pspA KT Phage shock protein A
MIHOOLGA_01835 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MIHOOLGA_01836 9.6e-253 gutA G MFS/sugar transport protein
MIHOOLGA_01837 2.1e-199 gutB 1.1.1.14 E Dehydrogenase
MIHOOLGA_01838 0.0 K NB-ARC domain
MIHOOLGA_01839 6.4e-16 S Terminase
MIHOOLGA_01840 4.2e-13 S Terminase
MIHOOLGA_01842 9e-270 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MIHOOLGA_01843 2.1e-209 L AlwI restriction endonuclease
MIHOOLGA_01844 4.1e-33
MIHOOLGA_01845 2.1e-45
MIHOOLGA_01846 2.3e-138 L Phage integrase SAM-like domain
MIHOOLGA_01847 1.1e-279 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIHOOLGA_01848 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIHOOLGA_01849 7.9e-129 ydiL S CAAX protease self-immunity
MIHOOLGA_01850 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MIHOOLGA_01851 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIHOOLGA_01852 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MIHOOLGA_01853 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MIHOOLGA_01854 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MIHOOLGA_01855 0.0 ydiF S ABC transporter
MIHOOLGA_01856 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIHOOLGA_01857 4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MIHOOLGA_01858 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MIHOOLGA_01859 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MIHOOLGA_01860 5.3e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIHOOLGA_01862 7.8e-08
MIHOOLGA_01864 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MIHOOLGA_01866 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
MIHOOLGA_01867 5.6e-138 ybbA S Putative esterase
MIHOOLGA_01868 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01869 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_01870 1.4e-165 feuA P Iron-uptake system-binding protein
MIHOOLGA_01871 5.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MIHOOLGA_01872 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
MIHOOLGA_01873 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MIHOOLGA_01874 2.3e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MIHOOLGA_01875 2.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_01876 1.4e-150 ybbH K transcriptional
MIHOOLGA_01877 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MIHOOLGA_01878 1.9e-86 ybbJ J acetyltransferase
MIHOOLGA_01879 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MIHOOLGA_01885 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_01886 4.1e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MIHOOLGA_01887 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MIHOOLGA_01888 4.4e-224 ybbR S protein conserved in bacteria
MIHOOLGA_01889 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIHOOLGA_01890 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIHOOLGA_01891 5.5e-99 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
MIHOOLGA_01892 4.4e-275 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIHOOLGA_01893 0.0 ybcC S Belongs to the UPF0753 family
MIHOOLGA_01894 4.7e-91 can 4.2.1.1 P carbonic anhydrase
MIHOOLGA_01896 5.6e-46
MIHOOLGA_01897 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MIHOOLGA_01898 5.1e-50 ybzH K Helix-turn-helix domain
MIHOOLGA_01899 7.2e-201 ybcL EGP Major facilitator Superfamily
MIHOOLGA_01901 9.1e-239 J 4Fe-4S single cluster domain
MIHOOLGA_01902 4.6e-277 V CAAX protease self-immunity
MIHOOLGA_01903 8e-134 skfE V ABC transporter
MIHOOLGA_01904 1.7e-246 skfF S ABC transporter
MIHOOLGA_01905 2.3e-90 C HEAT repeats
MIHOOLGA_01906 9.6e-79 txn CO Thioredoxin-like
MIHOOLGA_01907 1e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MIHOOLGA_01908 1.7e-122 T Transcriptional regulatory protein, C terminal
MIHOOLGA_01909 4e-134 T His Kinase A (phospho-acceptor) domain
MIHOOLGA_01911 6.7e-139 KLT Protein tyrosine kinase
MIHOOLGA_01912 2.6e-152 ybdN
MIHOOLGA_01913 3.6e-216 ybdO S Domain of unknown function (DUF4885)
MIHOOLGA_01914 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_01915 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
MIHOOLGA_01916 4.9e-30 ybxH S Family of unknown function (DUF5370)
MIHOOLGA_01917 2.6e-67 ybxI 3.5.2.6 V beta-lactamase
MIHOOLGA_01918 2.4e-41 ybxI 3.5.2.6 V beta-lactamase
MIHOOLGA_01919 5.1e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MIHOOLGA_01920 4.9e-41 ybyB
MIHOOLGA_01921 3e-290 ybeC E amino acid
MIHOOLGA_01922 1.5e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIHOOLGA_01923 7.3e-258 glpT G -transporter
MIHOOLGA_01924 1.5e-34 S Protein of unknown function (DUF2651)
MIHOOLGA_01925 4.8e-168 ybfA 3.4.15.5 K FR47-like protein
MIHOOLGA_01926 3.5e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
MIHOOLGA_01928 1.4e-159 ybfH EG EamA-like transporter family
MIHOOLGA_01929 5.2e-145 msmR K AraC-like ligand binding domain
MIHOOLGA_01930 2.1e-33 K sigma factor activity
MIHOOLGA_01931 9e-21 xhlB S SPP1 phage holin
MIHOOLGA_01932 2e-163 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
MIHOOLGA_01933 2.6e-56
MIHOOLGA_01934 8.9e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIHOOLGA_01935 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MIHOOLGA_01937 2.6e-166 S Alpha/beta hydrolase family
MIHOOLGA_01938 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIHOOLGA_01939 2.7e-85 ybfM S SNARE associated Golgi protein
MIHOOLGA_01940 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MIHOOLGA_01941 4.6e-45 ybfN
MIHOOLGA_01942 9.3e-253 S Erythromycin esterase
MIHOOLGA_01943 3.9e-192 yceA S Belongs to the UPF0176 family
MIHOOLGA_01944 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIHOOLGA_01945 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_01946 3e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIHOOLGA_01947 4.9e-128 K UTRA
MIHOOLGA_01949 2.7e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MIHOOLGA_01950 6.3e-260 mmuP E amino acid
MIHOOLGA_01951 3.3e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MIHOOLGA_01952 7.3e-256 agcS E Sodium alanine symporter
MIHOOLGA_01953 3.4e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
MIHOOLGA_01954 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
MIHOOLGA_01955 9e-170 glnL T Regulator
MIHOOLGA_01956 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MIHOOLGA_01957 5.8e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIHOOLGA_01958 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MIHOOLGA_01959 6.1e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIHOOLGA_01960 5.6e-124 ycbG K FCD
MIHOOLGA_01961 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
MIHOOLGA_01962 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
MIHOOLGA_01963 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MIHOOLGA_01964 7.5e-169 eamA1 EG spore germination
MIHOOLGA_01965 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_01966 9.9e-169 T PhoQ Sensor
MIHOOLGA_01967 4.1e-167 ycbN V ABC transporter, ATP-binding protein
MIHOOLGA_01968 1.5e-113 S ABC-2 family transporter protein
MIHOOLGA_01969 4.1e-52 ycbP S Protein of unknown function (DUF2512)
MIHOOLGA_01970 1.3e-78 sleB 3.5.1.28 M Cell wall
MIHOOLGA_01971 1.2e-134 ycbR T vWA found in TerF C terminus
MIHOOLGA_01972 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MIHOOLGA_01973 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MIHOOLGA_01974 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIHOOLGA_01975 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIHOOLGA_01976 6.6e-204 ycbU E Selenocysteine lyase
MIHOOLGA_01977 7.9e-226 lmrB EGP the major facilitator superfamily
MIHOOLGA_01978 4.8e-102 yxaF K Transcriptional regulator
MIHOOLGA_01979 2.4e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MIHOOLGA_01980 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIHOOLGA_01981 4.6e-56 S RDD family
MIHOOLGA_01982 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
MIHOOLGA_01983 2.9e-160 2.7.13.3 T GHKL domain
MIHOOLGA_01984 1.2e-126 lytR_2 T LytTr DNA-binding domain
MIHOOLGA_01985 5.9e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MIHOOLGA_01986 7.9e-200 natB CP ABC-2 family transporter protein
MIHOOLGA_01987 1.6e-174 yccK C Aldo keto reductase
MIHOOLGA_01988 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MIHOOLGA_01989 3.7e-276 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_01990 1.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_01991 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
MIHOOLGA_01992 2.7e-173 S response regulator aspartate phosphatase
MIHOOLGA_01993 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_01994 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MIHOOLGA_01995 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
MIHOOLGA_01996 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIHOOLGA_01997 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIHOOLGA_01998 6.1e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_01999 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MIHOOLGA_02000 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MIHOOLGA_02001 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MIHOOLGA_02002 1.4e-136 terC P Protein of unknown function (DUF475)
MIHOOLGA_02003 0.0 yceG S Putative component of 'biosynthetic module'
MIHOOLGA_02004 2e-192 yceH P Belongs to the TelA family
MIHOOLGA_02005 1.4e-215 naiP P Uncharacterised MFS-type transporter YbfB
MIHOOLGA_02006 7.9e-208 yceJ EGP Uncharacterised MFS-type transporter YbfB
MIHOOLGA_02007 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MIHOOLGA_02008 5.1e-229 proV 3.6.3.32 E glycine betaine
MIHOOLGA_02009 1.3e-127 opuAB P glycine betaine
MIHOOLGA_02010 5.3e-164 opuAC E glycine betaine
MIHOOLGA_02011 7e-217 amhX S amidohydrolase
MIHOOLGA_02012 5.6e-256 ycgA S Membrane
MIHOOLGA_02013 4.1e-81 ycgB
MIHOOLGA_02014 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MIHOOLGA_02015 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MIHOOLGA_02016 6.7e-290 lctP C L-lactate permease
MIHOOLGA_02017 3.6e-261 mdr EGP Major facilitator Superfamily
MIHOOLGA_02018 7.5e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_02019 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MIHOOLGA_02020 2.6e-151 yqcI S YqcI/YcgG family
MIHOOLGA_02021 4.8e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_02022 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MIHOOLGA_02023 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MIHOOLGA_02024 1.2e-108 tmrB S AAA domain
MIHOOLGA_02026 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIHOOLGA_02027 2e-100 yafE Q ubiE/COQ5 methyltransferase family
MIHOOLGA_02028 3.3e-20 yafE Q ubiE/COQ5 methyltransferase family
MIHOOLGA_02029 2.7e-177 oxyR3 K LysR substrate binding domain
MIHOOLGA_02030 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MIHOOLGA_02031 2.9e-145 ycgL S Predicted nucleotidyltransferase
MIHOOLGA_02032 5.1e-170 ycgM E Proline dehydrogenase
MIHOOLGA_02033 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MIHOOLGA_02034 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIHOOLGA_02035 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MIHOOLGA_02036 6.3e-146 ycgQ S membrane
MIHOOLGA_02037 1.2e-139 ycgR S permeases
MIHOOLGA_02038 6.1e-157 I alpha/beta hydrolase fold
MIHOOLGA_02039 1.5e-191 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MIHOOLGA_02040 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIHOOLGA_02041 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MIHOOLGA_02042 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIHOOLGA_02043 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIHOOLGA_02044 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MIHOOLGA_02045 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
MIHOOLGA_02046 1e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MIHOOLGA_02047 7.9e-108 yciB M ErfK YbiS YcfS YnhG
MIHOOLGA_02048 5e-226 yciC S GTPases (G3E family)
MIHOOLGA_02049 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MIHOOLGA_02050 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MIHOOLGA_02052 2e-74 yckC S membrane
MIHOOLGA_02053 9.6e-50 yckD S Protein of unknown function (DUF2680)
MIHOOLGA_02054 4.1e-45 K MarR family
MIHOOLGA_02055 9.3e-24
MIHOOLGA_02056 2.7e-121 S AAA domain
MIHOOLGA_02057 9.5e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIHOOLGA_02058 1.6e-67 nin S Competence protein J (ComJ)
MIHOOLGA_02059 3.5e-71 nucA M Deoxyribonuclease NucA/NucB
MIHOOLGA_02060 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
MIHOOLGA_02061 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MIHOOLGA_02062 5.2e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MIHOOLGA_02063 1.3e-63 hxlR K transcriptional
MIHOOLGA_02064 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_02065 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_02066 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MIHOOLGA_02067 1.7e-139 srfAD Q thioesterase
MIHOOLGA_02068 4.4e-225 EGP Major Facilitator Superfamily
MIHOOLGA_02069 1.2e-89 S YcxB-like protein
MIHOOLGA_02070 5.8e-161 ycxC EG EamA-like transporter family
MIHOOLGA_02071 2.3e-251 ycxD K GntR family transcriptional regulator
MIHOOLGA_02072 1.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MIHOOLGA_02073 3.7e-114 yczE S membrane
MIHOOLGA_02074 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIHOOLGA_02075 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MIHOOLGA_02076 3.5e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MIHOOLGA_02077 1.2e-160 bsdA K LysR substrate binding domain
MIHOOLGA_02078 4.9e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MIHOOLGA_02079 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MIHOOLGA_02080 4e-39 bsdD 4.1.1.61 S response to toxic substance
MIHOOLGA_02081 1.6e-82 yclD
MIHOOLGA_02082 6.6e-156 yclE 3.4.11.5 S Alpha beta hydrolase
MIHOOLGA_02083 9.2e-262 dtpT E amino acid peptide transporter
MIHOOLGA_02084 1.1e-298 yclG M Pectate lyase superfamily protein
MIHOOLGA_02086 1.7e-277 gerKA EG Spore germination protein
MIHOOLGA_02087 1.6e-230 gerKC S spore germination
MIHOOLGA_02088 3e-196 gerKB F Spore germination protein
MIHOOLGA_02089 7.3e-121 yclH P ABC transporter
MIHOOLGA_02090 2.1e-202 yclI V ABC transporter (permease) YclI
MIHOOLGA_02091 5.2e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_02092 8.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIHOOLGA_02093 3.1e-71 S aspartate phosphatase
MIHOOLGA_02097 2e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
MIHOOLGA_02099 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_02100 1.1e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_02101 5.2e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MIHOOLGA_02102 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MIHOOLGA_02103 1.4e-251 ycnB EGP Major facilitator Superfamily
MIHOOLGA_02104 5.5e-153 ycnC K Transcriptional regulator
MIHOOLGA_02105 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MIHOOLGA_02106 1.6e-45 ycnE S Monooxygenase
MIHOOLGA_02107 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MIHOOLGA_02108 1.6e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_02109 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIHOOLGA_02110 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIHOOLGA_02111 6.1e-149 glcU U Glucose uptake
MIHOOLGA_02112 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_02113 9.3e-99 ycnI S protein conserved in bacteria
MIHOOLGA_02114 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MIHOOLGA_02115 2.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MIHOOLGA_02116 3.4e-53
MIHOOLGA_02117 2.1e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MIHOOLGA_02118 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MIHOOLGA_02119 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MIHOOLGA_02120 8.5e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MIHOOLGA_02122 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MIHOOLGA_02123 6.3e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MIHOOLGA_02124 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MIHOOLGA_02126 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MIHOOLGA_02127 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
MIHOOLGA_02128 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MIHOOLGA_02129 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
MIHOOLGA_02130 4.4e-132 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MIHOOLGA_02131 2.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MIHOOLGA_02132 1.2e-132 kipR K Transcriptional regulator
MIHOOLGA_02133 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
MIHOOLGA_02135 1.4e-49 yczJ S biosynthesis
MIHOOLGA_02136 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MIHOOLGA_02137 2.4e-172 ydhF S Oxidoreductase
MIHOOLGA_02138 0.0 mtlR K transcriptional regulator, MtlR
MIHOOLGA_02139 7.9e-293 ydaB IQ acyl-CoA ligase
MIHOOLGA_02140 1.3e-97 ydaC Q Methyltransferase domain
MIHOOLGA_02141 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_02142 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MIHOOLGA_02143 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIHOOLGA_02144 6.8e-77 ydaG 1.4.3.5 S general stress protein
MIHOOLGA_02146 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MIHOOLGA_02147 3.3e-46 ydzA EGP Major facilitator Superfamily
MIHOOLGA_02148 2.5e-74 lrpC K Transcriptional regulator
MIHOOLGA_02149 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIHOOLGA_02150 1.5e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MIHOOLGA_02151 2.7e-149 ydaK T Diguanylate cyclase, GGDEF domain
MIHOOLGA_02152 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MIHOOLGA_02153 1.3e-232 ydaM M Glycosyl transferase family group 2
MIHOOLGA_02154 0.0 ydaN S Bacterial cellulose synthase subunit
MIHOOLGA_02155 0.0 ydaO E amino acid
MIHOOLGA_02156 2.1e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MIHOOLGA_02157 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MIHOOLGA_02158 2.1e-39
MIHOOLGA_02159 6.6e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MIHOOLGA_02161 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MIHOOLGA_02162 1.1e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MIHOOLGA_02164 8.9e-59 ydbB G Cupin domain
MIHOOLGA_02165 1.3e-60 ydbC S Domain of unknown function (DUF4937
MIHOOLGA_02166 3.5e-154 ydbD P Catalase
MIHOOLGA_02167 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MIHOOLGA_02168 3.6e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIHOOLGA_02169 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
MIHOOLGA_02170 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIHOOLGA_02171 9.7e-181 ydbI S AI-2E family transporter
MIHOOLGA_02173 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MIHOOLGA_02174 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIHOOLGA_02175 2.7e-52 ydbL
MIHOOLGA_02176 3.7e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MIHOOLGA_02177 1.1e-18 S Fur-regulated basic protein B
MIHOOLGA_02178 2.2e-07 S Fur-regulated basic protein A
MIHOOLGA_02179 1.6e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIHOOLGA_02180 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MIHOOLGA_02181 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MIHOOLGA_02182 7.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIHOOLGA_02183 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MIHOOLGA_02184 2.1e-82 ydbS S Bacterial PH domain
MIHOOLGA_02185 2.4e-257 ydbT S Membrane
MIHOOLGA_02186 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MIHOOLGA_02187 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIHOOLGA_02188 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MIHOOLGA_02189 5.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIHOOLGA_02190 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MIHOOLGA_02191 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MIHOOLGA_02192 1.3e-143 rsbR T Positive regulator of sigma-B
MIHOOLGA_02193 5.2e-57 rsbS T antagonist
MIHOOLGA_02194 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MIHOOLGA_02195 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MIHOOLGA_02196 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MIHOOLGA_02197 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MIHOOLGA_02198 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_02199 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MIHOOLGA_02200 0.0 yhgF K COG2183 Transcriptional accessory protein
MIHOOLGA_02201 3.1e-83 ydcK S Belongs to the SprT family
MIHOOLGA_02209 5.5e-86 S DinB superfamily
MIHOOLGA_02210 5.2e-74 S response regulator aspartate phosphatase
MIHOOLGA_02212 1.7e-35 G Toxic component of a toxin-antitoxin (TA) module. An RNase
MIHOOLGA_02213 3.5e-80 T NACHT domain
MIHOOLGA_02214 8.6e-49 S SMI1-KNR4 cell-wall
MIHOOLGA_02215 1.1e-58 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MIHOOLGA_02216 2.1e-140 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MIHOOLGA_02217 1.7e-32 K Helix-turn-helix XRE-family like proteins
MIHOOLGA_02218 4.6e-42
MIHOOLGA_02219 7.5e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MIHOOLGA_02220 8.7e-30 cspL K Cold shock
MIHOOLGA_02221 2.3e-78 carD K Transcription factor
MIHOOLGA_02222 3.4e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MIHOOLGA_02223 3.1e-164 rhaS5 K AraC-like ligand binding domain
MIHOOLGA_02224 2.7e-169 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MIHOOLGA_02225 1.8e-164 ydeE K AraC family transcriptional regulator
MIHOOLGA_02226 4.3e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_02227 2.3e-216 ydeG EGP Major facilitator superfamily
MIHOOLGA_02228 1.4e-44 ydeH
MIHOOLGA_02229 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MIHOOLGA_02230 7.8e-112
MIHOOLGA_02231 1.1e-31 S SNARE associated Golgi protein
MIHOOLGA_02232 8.3e-15 ptsH G PTS HPr component phosphorylation site
MIHOOLGA_02233 8.8e-85 K Transcriptional regulator C-terminal region
MIHOOLGA_02234 4.5e-152 ydeK EG -transporter
MIHOOLGA_02235 3.8e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_02236 1e-72 maoC I N-terminal half of MaoC dehydratase
MIHOOLGA_02237 1.6e-105 ydeN S Serine hydrolase
MIHOOLGA_02238 2.3e-56 K HxlR-like helix-turn-helix
MIHOOLGA_02239 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIHOOLGA_02240 1.9e-177 ydeR EGP Major facilitator Superfamily
MIHOOLGA_02241 2.1e-103 ydeS K Transcriptional regulator
MIHOOLGA_02242 2.8e-57 arsR K transcriptional
MIHOOLGA_02243 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIHOOLGA_02244 2.1e-148 ydfB J GNAT acetyltransferase
MIHOOLGA_02245 3.7e-160 ydfC EG EamA-like transporter family
MIHOOLGA_02246 4.3e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIHOOLGA_02247 1.1e-115 ydfE S Flavin reductase like domain
MIHOOLGA_02248 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MIHOOLGA_02249 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIHOOLGA_02251 3e-175 ydfH 2.7.13.3 T Histidine kinase
MIHOOLGA_02252 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_02253 0.0 ydfJ S drug exporters of the RND superfamily
MIHOOLGA_02254 2.7e-115 S Protein of unknown function (DUF554)
MIHOOLGA_02255 9.2e-147 K Bacterial transcription activator, effector binding domain
MIHOOLGA_02256 1.7e-16 S response regulator aspartate phosphatase
MIHOOLGA_02257 5.6e-11 S response regulator aspartate phosphatase
MIHOOLGA_02258 5.4e-13
MIHOOLGA_02261 5.6e-32 L COG3666 Transposase and inactivated derivatives
MIHOOLGA_02262 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIHOOLGA_02263 1.2e-109 ydfN C nitroreductase
MIHOOLGA_02264 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MIHOOLGA_02265 8.8e-63 mhqP S DoxX
MIHOOLGA_02266 6.3e-57 traF CO Thioredoxin
MIHOOLGA_02267 1.9e-15 ydgA S Spore germination protein gerPA/gerPF
MIHOOLGA_02268 6.3e-29
MIHOOLGA_02270 4.4e-118 ydfR S Protein of unknown function (DUF421)
MIHOOLGA_02271 5.2e-122 ydfS S Protein of unknown function (DUF421)
MIHOOLGA_02272 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MIHOOLGA_02273 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MIHOOLGA_02274 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MIHOOLGA_02275 3.2e-96 K Bacterial regulatory proteins, tetR family
MIHOOLGA_02276 1.4e-51 S DoxX-like family
MIHOOLGA_02277 5e-84 yycN 2.3.1.128 K Acetyltransferase
MIHOOLGA_02278 9.2e-303 expZ S ABC transporter
MIHOOLGA_02279 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_02280 4.3e-89 dinB S DinB family
MIHOOLGA_02281 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_02282 0.0 ydgH S drug exporters of the RND superfamily
MIHOOLGA_02283 8.8e-113 drgA C nitroreductase
MIHOOLGA_02284 7.1e-69 ydgJ K Winged helix DNA-binding domain
MIHOOLGA_02285 2.8e-208 tcaB EGP Major facilitator Superfamily
MIHOOLGA_02286 1.2e-121 ydhB S membrane transporter protein
MIHOOLGA_02287 2.5e-121 ydhC K FCD
MIHOOLGA_02288 1.6e-243 ydhD M Glycosyl hydrolase
MIHOOLGA_02289 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MIHOOLGA_02290 1.6e-123
MIHOOLGA_02291 1.2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MIHOOLGA_02292 8.7e-68 frataxin S Domain of unknown function (DU1801)
MIHOOLGA_02294 1.2e-82 K Acetyltransferase (GNAT) domain
MIHOOLGA_02295 7.6e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MIHOOLGA_02296 1.9e-93 ydhK M Protein of unknown function (DUF1541)
MIHOOLGA_02297 2.3e-199 pbuE EGP Major facilitator Superfamily
MIHOOLGA_02298 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIHOOLGA_02299 8.7e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIHOOLGA_02300 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIHOOLGA_02301 3.6e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIHOOLGA_02302 1.1e-132 ydhQ K UTRA
MIHOOLGA_02303 6.8e-107 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MIHOOLGA_02304 2e-29 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MIHOOLGA_02305 9.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MIHOOLGA_02306 2.6e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MIHOOLGA_02307 6.1e-157 ydhU P Catalase
MIHOOLGA_02310 2.7e-41 S DNase/tRNase domain of colicin-like bacteriocin
MIHOOLGA_02311 4.5e-31 S SMI1 / KNR4 family
MIHOOLGA_02312 8.4e-31
MIHOOLGA_02313 1.7e-25 S SMI1-KNR4 cell-wall
MIHOOLGA_02314 1e-22 S SMI1-KNR4 cell-wall
MIHOOLGA_02315 1.4e-46
MIHOOLGA_02320 1.2e-95 S Suppressor of fused protein (SUFU)
MIHOOLGA_02321 2.5e-30
MIHOOLGA_02323 7.3e-16 xkdM S Phage tail tube protein
MIHOOLGA_02324 1.6e-13 yqaS L DNA packaging
MIHOOLGA_02325 1.4e-19
MIHOOLGA_02327 3.7e-26 cotD S Inner spore coat protein D
MIHOOLGA_02328 5.5e-40 L Transposase
MIHOOLGA_02332 8.6e-153 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MIHOOLGA_02333 2e-89 K Transcriptional regulator PadR-like family
MIHOOLGA_02334 5.8e-97 adk 2.7.4.3 F adenylate kinase activity
MIHOOLGA_02336 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIHOOLGA_02338 3.6e-112 tetR3 K Transcriptional regulator
MIHOOLGA_02339 2e-215 mepA V Multidrug transporter MatE
MIHOOLGA_02340 3.5e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MIHOOLGA_02341 2.5e-104 yrkJ S membrane transporter protein
MIHOOLGA_02342 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
MIHOOLGA_02343 3e-204 yrkH P Rhodanese Homology Domain
MIHOOLGA_02344 1e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
MIHOOLGA_02345 4.3e-83 yrkE O DsrE/DsrF/DrsH-like family
MIHOOLGA_02346 7.8e-39 yrkD S protein conserved in bacteria
MIHOOLGA_02347 1.1e-106 yrkC G Cupin domain
MIHOOLGA_02348 3.1e-150 bltR K helix_turn_helix, mercury resistance
MIHOOLGA_02349 1.8e-210 blt EGP Major facilitator Superfamily
MIHOOLGA_02350 2e-82 bltD 2.3.1.57 K FR47-like protein
MIHOOLGA_02351 3.7e-230 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MIHOOLGA_02352 3.9e-16 S YrzO-like protein
MIHOOLGA_02353 1.4e-170 yrdR EG EamA-like transporter family
MIHOOLGA_02354 3e-159 yrdQ K Transcriptional regulator
MIHOOLGA_02355 1.3e-198 trkA P Oxidoreductase
MIHOOLGA_02356 1.3e-157 czcD P COG1230 Co Zn Cd efflux system component
MIHOOLGA_02357 1.9e-65 yodA S tautomerase
MIHOOLGA_02358 6e-45 gltR K LysR substrate binding domain
MIHOOLGA_02359 3.2e-92 gltR K LysR substrate binding domain
MIHOOLGA_02360 7.4e-54 C COG2041 Sulfite oxidase and related enzymes
MIHOOLGA_02361 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
MIHOOLGA_02362 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MIHOOLGA_02363 1.1e-136 azlC E AzlC protein
MIHOOLGA_02364 6.3e-79 bkdR K helix_turn_helix ASNC type
MIHOOLGA_02365 4.5e-45 yrdF K ribonuclease inhibitor
MIHOOLGA_02366 7.5e-225 cypA C Cytochrome P450
MIHOOLGA_02368 1.7e-99 yrdC 3.5.1.19 Q Isochorismatase family
MIHOOLGA_02369 6.8e-55 S Protein of unknown function (DUF2568)
MIHOOLGA_02370 5.4e-89 yrdA S DinB family
MIHOOLGA_02371 4.2e-166 aadK G Streptomycin adenylyltransferase
MIHOOLGA_02372 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MIHOOLGA_02373 2.8e-134 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIHOOLGA_02374 3.7e-123 yrpD S Domain of unknown function, YrpD
MIHOOLGA_02376 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MIHOOLGA_02377 9.1e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_02378 5.5e-186 yrpG C Aldo/keto reductase family
MIHOOLGA_02379 1.4e-224 yraO C Citrate transporter
MIHOOLGA_02380 3.4e-163 yraN K Transcriptional regulator
MIHOOLGA_02381 5.9e-205 yraM S PrpF protein
MIHOOLGA_02382 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MIHOOLGA_02383 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_02384 6.6e-153 S Alpha beta hydrolase
MIHOOLGA_02385 4.9e-60 T sh3 domain protein
MIHOOLGA_02386 5.4e-61 T sh3 domain protein
MIHOOLGA_02387 3.8e-66 E Glyoxalase-like domain
MIHOOLGA_02388 1.5e-36 yraG
MIHOOLGA_02389 6.4e-63 yraF M Spore coat protein
MIHOOLGA_02390 1.2e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIHOOLGA_02391 7.5e-26 yraE
MIHOOLGA_02392 1.1e-47 yraD M Spore coat protein
MIHOOLGA_02393 4.3e-47 yraB K helix_turn_helix, mercury resistance
MIHOOLGA_02394 8.7e-27 yphJ 4.1.1.44 S peroxiredoxin activity
MIHOOLGA_02395 5.6e-39 adhA 1.1.1.1 C alcohol dehydrogenase
MIHOOLGA_02396 5.4e-104 adhA 1.1.1.1 C alcohol dehydrogenase
MIHOOLGA_02397 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MIHOOLGA_02398 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MIHOOLGA_02399 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MIHOOLGA_02400 1.1e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MIHOOLGA_02401 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MIHOOLGA_02402 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
MIHOOLGA_02403 0.0 levR K PTS system fructose IIA component
MIHOOLGA_02404 8.7e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_02405 3.6e-106 yrhP E LysE type translocator
MIHOOLGA_02406 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
MIHOOLGA_02407 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_02408 2.9e-151 rsiV S Protein of unknown function (DUF3298)
MIHOOLGA_02409 0.0 yrhL I Acyltransferase family
MIHOOLGA_02410 1.3e-45 yrhK S YrhK-like protein
MIHOOLGA_02411 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MIHOOLGA_02412 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MIHOOLGA_02413 2.6e-89 yrhH Q methyltransferase
MIHOOLGA_02416 1.8e-142 focA P Formate nitrite
MIHOOLGA_02418 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MIHOOLGA_02419 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MIHOOLGA_02420 1.4e-78 yrhD S Protein of unknown function (DUF1641)
MIHOOLGA_02421 5.1e-34 yrhC S YrhC-like protein
MIHOOLGA_02422 2.8e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MIHOOLGA_02423 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MIHOOLGA_02424 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIHOOLGA_02425 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MIHOOLGA_02426 1e-25 yrzA S Protein of unknown function (DUF2536)
MIHOOLGA_02427 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MIHOOLGA_02428 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MIHOOLGA_02429 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIHOOLGA_02430 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MIHOOLGA_02431 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MIHOOLGA_02432 4.7e-171 yegQ O Peptidase U32
MIHOOLGA_02433 8.6e-119 yrrM 2.1.1.104 S O-methyltransferase
MIHOOLGA_02434 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIHOOLGA_02435 1.2e-45 yrzB S Belongs to the UPF0473 family
MIHOOLGA_02436 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIHOOLGA_02437 1.7e-41 yrzL S Belongs to the UPF0297 family
MIHOOLGA_02438 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIHOOLGA_02439 2.7e-170 yrrI S AI-2E family transporter
MIHOOLGA_02440 2.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIHOOLGA_02441 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
MIHOOLGA_02442 8e-109 gluC P ABC transporter
MIHOOLGA_02443 7.6e-107 glnP P ABC transporter
MIHOOLGA_02444 8e-08 S Protein of unknown function (DUF3918)
MIHOOLGA_02445 9.8e-31 yrzR
MIHOOLGA_02446 8.6e-81 yrrD S protein conserved in bacteria
MIHOOLGA_02447 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MIHOOLGA_02448 1.4e-15 S COG0457 FOG TPR repeat
MIHOOLGA_02449 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MIHOOLGA_02450 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
MIHOOLGA_02451 1.2e-70 cymR K Transcriptional regulator
MIHOOLGA_02452 4.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MIHOOLGA_02453 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MIHOOLGA_02454 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIHOOLGA_02455 2.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MIHOOLGA_02457 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MIHOOLGA_02458 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIHOOLGA_02459 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIHOOLGA_02460 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIHOOLGA_02461 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MIHOOLGA_02462 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MIHOOLGA_02463 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MIHOOLGA_02464 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIHOOLGA_02465 4.7e-48 yrzD S Post-transcriptional regulator
MIHOOLGA_02466 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_02467 1.1e-113 yrbG S membrane
MIHOOLGA_02468 1.2e-74 yrzE S Protein of unknown function (DUF3792)
MIHOOLGA_02469 1.1e-38 yajC U Preprotein translocase subunit YajC
MIHOOLGA_02470 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIHOOLGA_02471 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIHOOLGA_02472 1e-17 yrzS S Protein of unknown function (DUF2905)
MIHOOLGA_02473 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIHOOLGA_02474 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIHOOLGA_02475 4.8e-93 bofC S BofC C-terminal domain
MIHOOLGA_02476 5.3e-253 csbX EGP Major facilitator Superfamily
MIHOOLGA_02477 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MIHOOLGA_02478 6.5e-119 yrzF T serine threonine protein kinase
MIHOOLGA_02480 1.3e-50 S Family of unknown function (DUF5412)
MIHOOLGA_02481 1.8e-262 alsT E Sodium alanine symporter
MIHOOLGA_02482 3.6e-126 yebC K transcriptional regulatory protein
MIHOOLGA_02483 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIHOOLGA_02484 1.8e-156 safA M spore coat assembly protein SafA
MIHOOLGA_02485 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIHOOLGA_02486 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MIHOOLGA_02487 2.6e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MIHOOLGA_02488 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
MIHOOLGA_02489 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MIHOOLGA_02490 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MIHOOLGA_02491 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MIHOOLGA_02492 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIHOOLGA_02493 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MIHOOLGA_02494 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MIHOOLGA_02495 4.1e-56 ysxB J ribosomal protein
MIHOOLGA_02496 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MIHOOLGA_02497 5.9e-160 spoIVFB S Stage IV sporulation protein
MIHOOLGA_02498 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MIHOOLGA_02499 4.7e-143 minD D Belongs to the ParA family
MIHOOLGA_02500 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MIHOOLGA_02501 1.4e-84 mreD M shape-determining protein
MIHOOLGA_02502 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MIHOOLGA_02503 1.8e-184 mreB D Rod shape-determining protein MreB
MIHOOLGA_02504 5.9e-126 radC E Belongs to the UPF0758 family
MIHOOLGA_02505 2.8e-102 maf D septum formation protein Maf
MIHOOLGA_02506 3.3e-162 spoIIB S Sporulation related domain
MIHOOLGA_02507 5.6e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MIHOOLGA_02508 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MIHOOLGA_02509 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIHOOLGA_02510 1.6e-25
MIHOOLGA_02511 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIHOOLGA_02512 1.4e-216 spoVID M stage VI sporulation protein D
MIHOOLGA_02513 7.3e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIHOOLGA_02514 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
MIHOOLGA_02515 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIHOOLGA_02516 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MIHOOLGA_02517 3.6e-146 hemX O cytochrome C
MIHOOLGA_02518 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIHOOLGA_02519 1.4e-89 ysxD
MIHOOLGA_02520 9.8e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MIHOOLGA_02521 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIHOOLGA_02522 2.8e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MIHOOLGA_02523 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIHOOLGA_02524 1.2e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIHOOLGA_02525 1.9e-186 ysoA H Tetratricopeptide repeat
MIHOOLGA_02526 2e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIHOOLGA_02527 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIHOOLGA_02528 1.8e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIHOOLGA_02529 1.3e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIHOOLGA_02530 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIHOOLGA_02531 1.6e-83 ilvN 2.2.1.6 E Acetolactate synthase
MIHOOLGA_02532 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MIHOOLGA_02534 7.6e-82 ysnE K acetyltransferase
MIHOOLGA_02535 9.1e-134 ysnF S protein conserved in bacteria
MIHOOLGA_02537 1.8e-92 ysnB S Phosphoesterase
MIHOOLGA_02538 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIHOOLGA_02539 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIHOOLGA_02540 6.5e-196 gerM S COG5401 Spore germination protein
MIHOOLGA_02541 5.1e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIHOOLGA_02542 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_02543 3.3e-30 gerE K Transcriptional regulator
MIHOOLGA_02544 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MIHOOLGA_02545 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIHOOLGA_02546 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIHOOLGA_02547 2.4e-107 sdhC C succinate dehydrogenase
MIHOOLGA_02548 1.2e-79 yslB S Protein of unknown function (DUF2507)
MIHOOLGA_02549 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MIHOOLGA_02550 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIHOOLGA_02551 2e-52 trxA O Belongs to the thioredoxin family
MIHOOLGA_02552 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MIHOOLGA_02554 2.1e-177 etfA C Electron transfer flavoprotein
MIHOOLGA_02555 4.5e-135 etfB C Electron transfer flavoprotein
MIHOOLGA_02556 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIHOOLGA_02557 2.7e-100 fadR K Transcriptional regulator
MIHOOLGA_02558 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIHOOLGA_02559 7.3e-68 yshE S membrane
MIHOOLGA_02560 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MIHOOLGA_02561 0.0 polX L COG1796 DNA polymerase IV (family X)
MIHOOLGA_02562 1.3e-85 cvpA S membrane protein, required for colicin V production
MIHOOLGA_02563 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MIHOOLGA_02564 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIHOOLGA_02565 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIHOOLGA_02566 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIHOOLGA_02567 1e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIHOOLGA_02568 5.8e-32 sspI S Belongs to the SspI family
MIHOOLGA_02569 1.3e-207 ysfB KT regulator
MIHOOLGA_02570 2.7e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
MIHOOLGA_02571 1.7e-254 glcF C Glycolate oxidase
MIHOOLGA_02572 3.4e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MIHOOLGA_02573 1.4e-278 cstA T Carbon starvation protein
MIHOOLGA_02574 3.8e-44 cstA T Carbon starvation protein
MIHOOLGA_02575 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MIHOOLGA_02576 4.9e-143 araQ G transport system permease
MIHOOLGA_02577 2.7e-166 araP G carbohydrate transport
MIHOOLGA_02578 6.2e-254 araN G carbohydrate transport
MIHOOLGA_02579 2e-219 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MIHOOLGA_02580 3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MIHOOLGA_02581 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MIHOOLGA_02582 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MIHOOLGA_02583 3e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MIHOOLGA_02584 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MIHOOLGA_02585 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MIHOOLGA_02586 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MIHOOLGA_02587 1.6e-12 ysdA S Membrane
MIHOOLGA_02588 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIHOOLGA_02589 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MIHOOLGA_02590 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIHOOLGA_02592 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MIHOOLGA_02593 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MIHOOLGA_02594 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
MIHOOLGA_02595 0.0 lytS 2.7.13.3 T Histidine kinase
MIHOOLGA_02596 2.8e-148 ysaA S HAD-hyrolase-like
MIHOOLGA_02597 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIHOOLGA_02599 1.4e-158 ytxC S YtxC-like family
MIHOOLGA_02600 1.4e-110 ytxB S SNARE associated Golgi protein
MIHOOLGA_02601 6.6e-173 dnaI L Primosomal protein DnaI
MIHOOLGA_02602 1.5e-264 dnaB L Membrane attachment protein
MIHOOLGA_02603 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIHOOLGA_02604 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIHOOLGA_02605 1.4e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIHOOLGA_02606 9.9e-67 ytcD K Transcriptional regulator
MIHOOLGA_02607 7.3e-201 ytbD EGP Major facilitator Superfamily
MIHOOLGA_02608 8.9e-161 ytbE S reductase
MIHOOLGA_02609 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIHOOLGA_02610 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MIHOOLGA_02611 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MIHOOLGA_02612 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIHOOLGA_02613 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MIHOOLGA_02614 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_02615 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MIHOOLGA_02616 4.1e-242 icd 1.1.1.42 C isocitrate
MIHOOLGA_02617 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MIHOOLGA_02618 1.1e-70 yeaL S membrane
MIHOOLGA_02619 9.9e-192 ytvI S sporulation integral membrane protein YtvI
MIHOOLGA_02620 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MIHOOLGA_02621 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MIHOOLGA_02622 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MIHOOLGA_02623 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MIHOOLGA_02624 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIHOOLGA_02625 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MIHOOLGA_02626 0.0 dnaE 2.7.7.7 L DNA polymerase
MIHOOLGA_02627 3.2e-56 ytrH S Sporulation protein YtrH
MIHOOLGA_02628 8.2e-69 ytrI
MIHOOLGA_02629 9.2e-29
MIHOOLGA_02630 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MIHOOLGA_02631 2.4e-47 ytpI S YtpI-like protein
MIHOOLGA_02632 8e-241 ytoI K transcriptional regulator containing CBS domains
MIHOOLGA_02633 4.4e-158 ytnM S membrane transporter protein
MIHOOLGA_02634 4.8e-235 ytnL 3.5.1.47 E hydrolase activity
MIHOOLGA_02635 9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MIHOOLGA_02636 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_02637 8.4e-47 ytnI O COG0695 Glutaredoxin and related proteins
MIHOOLGA_02638 3.1e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_02639 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIHOOLGA_02640 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MIHOOLGA_02641 3.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
MIHOOLGA_02642 3.7e-148 tcyK M Bacterial periplasmic substrate-binding proteins
MIHOOLGA_02643 4.4e-149 tcyK ET Bacterial periplasmic substrate-binding proteins
MIHOOLGA_02644 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
MIHOOLGA_02645 1.2e-171 ytlI K LysR substrate binding domain
MIHOOLGA_02646 1.7e-130 ytkL S Belongs to the UPF0173 family
MIHOOLGA_02647 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_02649 2e-266 argH 4.3.2.1 E argininosuccinate lyase
MIHOOLGA_02650 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIHOOLGA_02651 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MIHOOLGA_02652 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIHOOLGA_02653 7e-165 ytxK 2.1.1.72 L DNA methylase
MIHOOLGA_02654 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MIHOOLGA_02655 8.7e-70 ytfJ S Sporulation protein YtfJ
MIHOOLGA_02656 4.7e-115 ytfI S Protein of unknown function (DUF2953)
MIHOOLGA_02657 5e-87 yteJ S RDD family
MIHOOLGA_02658 3.5e-180 sppA OU signal peptide peptidase SppA
MIHOOLGA_02659 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIHOOLGA_02660 0.0 ytcJ S amidohydrolase
MIHOOLGA_02661 1.7e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIHOOLGA_02662 2e-29 sspB S spore protein
MIHOOLGA_02663 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIHOOLGA_02664 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
MIHOOLGA_02665 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MIHOOLGA_02666 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MIHOOLGA_02667 8.6e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MIHOOLGA_02668 1e-108 yttP K Transcriptional regulator
MIHOOLGA_02669 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MIHOOLGA_02670 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MIHOOLGA_02671 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIHOOLGA_02673 2.3e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIHOOLGA_02674 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIHOOLGA_02675 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MIHOOLGA_02676 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MIHOOLGA_02677 5.1e-223 acuC BQ histone deacetylase
MIHOOLGA_02678 4e-117 motS N Flagellar motor protein
MIHOOLGA_02679 1.5e-144 motA N flagellar motor
MIHOOLGA_02680 8.4e-182 ccpA K catabolite control protein A
MIHOOLGA_02681 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MIHOOLGA_02682 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
MIHOOLGA_02683 6.6e-17 ytxH S COG4980 Gas vesicle protein
MIHOOLGA_02684 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MIHOOLGA_02685 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MIHOOLGA_02686 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MIHOOLGA_02687 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIHOOLGA_02688 9.8e-149 ytpQ S Belongs to the UPF0354 family
MIHOOLGA_02689 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MIHOOLGA_02690 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MIHOOLGA_02691 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MIHOOLGA_02692 1.1e-50 ytzB S small secreted protein
MIHOOLGA_02693 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MIHOOLGA_02694 8.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MIHOOLGA_02695 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIHOOLGA_02696 2e-45 ytzH S YtzH-like protein
MIHOOLGA_02697 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MIHOOLGA_02698 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MIHOOLGA_02699 8.6e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MIHOOLGA_02700 2.2e-165 ytlQ
MIHOOLGA_02701 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MIHOOLGA_02702 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIHOOLGA_02703 5.1e-270 pepV 3.5.1.18 E Dipeptidase
MIHOOLGA_02704 2.1e-225 pbuO S permease
MIHOOLGA_02705 1.6e-200 ythQ U Bacterial ABC transporter protein EcsB
MIHOOLGA_02706 4.8e-131 ythP V ABC transporter
MIHOOLGA_02707 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MIHOOLGA_02708 3.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIHOOLGA_02709 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_02710 8.2e-232 ytfP S HI0933-like protein
MIHOOLGA_02711 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MIHOOLGA_02712 3.1e-26 yteV S Sporulation protein Cse60
MIHOOLGA_02713 6.5e-114 yteU S Integral membrane protein
MIHOOLGA_02714 1.5e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MIHOOLGA_02715 1.3e-72 yteS G transport
MIHOOLGA_02716 4.3e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MIHOOLGA_02717 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MIHOOLGA_02718 0.0 ytdP K Transcriptional regulator
MIHOOLGA_02719 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MIHOOLGA_02720 7.4e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
MIHOOLGA_02721 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MIHOOLGA_02722 2.7e-224 bioI 1.14.14.46 C Cytochrome P450
MIHOOLGA_02723 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIHOOLGA_02724 2.9e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MIHOOLGA_02725 2.3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MIHOOLGA_02726 6e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MIHOOLGA_02727 8.9e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MIHOOLGA_02728 3.7e-173 ytaP S Acetyl xylan esterase (AXE1)
MIHOOLGA_02729 1.5e-189 msmR K Transcriptional regulator
MIHOOLGA_02730 4.4e-244 msmE G Bacterial extracellular solute-binding protein
MIHOOLGA_02731 1.8e-167 amyD P ABC transporter
MIHOOLGA_02732 4.4e-144 amyC P ABC transporter (permease)
MIHOOLGA_02733 7.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIHOOLGA_02734 2.1e-51 ytwF P Sulfurtransferase
MIHOOLGA_02735 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIHOOLGA_02736 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MIHOOLGA_02737 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MIHOOLGA_02738 4.6e-211 yttB EGP Major facilitator Superfamily
MIHOOLGA_02739 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MIHOOLGA_02740 0.0 bceB V ABC transporter (permease)
MIHOOLGA_02741 1.1e-138 bceA V ABC transporter, ATP-binding protein
MIHOOLGA_02742 1.1e-184 T PhoQ Sensor
MIHOOLGA_02743 4.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_02744 7.2e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIHOOLGA_02745 9.1e-127 ytrE V ABC transporter, ATP-binding protein
MIHOOLGA_02746 9.8e-127
MIHOOLGA_02747 5.9e-148 P ABC-2 family transporter protein
MIHOOLGA_02748 4.2e-161 ytrB P abc transporter atp-binding protein
MIHOOLGA_02749 5.1e-66 ytrA K GntR family transcriptional regulator
MIHOOLGA_02751 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MIHOOLGA_02752 8.9e-189 yhcC S Fe-S oxidoreductase
MIHOOLGA_02753 1.1e-104 ytqB J Putative rRNA methylase
MIHOOLGA_02754 1.3e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MIHOOLGA_02755 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MIHOOLGA_02756 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MIHOOLGA_02757 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_02758 0.0 asnB 6.3.5.4 E Asparagine synthase
MIHOOLGA_02759 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIHOOLGA_02760 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MIHOOLGA_02761 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MIHOOLGA_02762 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MIHOOLGA_02763 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MIHOOLGA_02764 1.4e-144 ytlC P ABC transporter
MIHOOLGA_02765 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIHOOLGA_02766 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MIHOOLGA_02767 6e-62 ytkC S Bacteriophage holin family
MIHOOLGA_02768 2.1e-76 dps P Belongs to the Dps family
MIHOOLGA_02770 6.9e-72 ytkA S YtkA-like
MIHOOLGA_02771 1.1e-86 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIHOOLGA_02772 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MIHOOLGA_02773 3.6e-41 rpmE2 J Ribosomal protein L31
MIHOOLGA_02774 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MIHOOLGA_02775 2.4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MIHOOLGA_02776 1.1e-24 S Domain of Unknown Function (DUF1540)
MIHOOLGA_02777 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MIHOOLGA_02778 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIHOOLGA_02779 3e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIHOOLGA_02780 5.7e-169 troA P Belongs to the bacterial solute-binding protein 9 family
MIHOOLGA_02781 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MIHOOLGA_02782 2.4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MIHOOLGA_02783 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MIHOOLGA_02784 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MIHOOLGA_02785 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MIHOOLGA_02786 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
MIHOOLGA_02787 2.6e-132 dksA T COG1734 DnaK suppressor protein
MIHOOLGA_02788 1.3e-153 galU 2.7.7.9 M Nucleotidyl transferase
MIHOOLGA_02789 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIHOOLGA_02790 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MIHOOLGA_02791 3.7e-232 ytcC M Glycosyltransferase Family 4
MIHOOLGA_02793 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MIHOOLGA_02794 1.2e-216 cotSA M Glycosyl transferases group 1
MIHOOLGA_02795 4.8e-204 cotI S Spore coat protein
MIHOOLGA_02796 1.3e-76 tspO T membrane
MIHOOLGA_02797 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIHOOLGA_02798 1.5e-60 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MIHOOLGA_02799 1.3e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MIHOOLGA_02800 3.2e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MIHOOLGA_02801 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MIHOOLGA_02802 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MIHOOLGA_02811 7.8e-08
MIHOOLGA_02812 1.3e-09
MIHOOLGA_02819 2e-08
MIHOOLGA_02824 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_02825 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MIHOOLGA_02826 4e-63 yngL S Protein of unknown function (DUF1360)
MIHOOLGA_02827 1.1e-302 yngK T Glycosyl hydrolase-like 10
MIHOOLGA_02828 4.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MIHOOLGA_02829 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIHOOLGA_02830 1.4e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MIHOOLGA_02831 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MIHOOLGA_02832 4e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MIHOOLGA_02833 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIHOOLGA_02834 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIHOOLGA_02835 6.8e-231 nrnB S phosphohydrolase (DHH superfamily)
MIHOOLGA_02836 5.5e-104 yngC S membrane-associated protein
MIHOOLGA_02837 2.9e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIHOOLGA_02838 2e-79 yngA S membrane
MIHOOLGA_02839 5.4e-297 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MIHOOLGA_02840 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MIHOOLGA_02842 2.6e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MIHOOLGA_02843 9e-251 agcS E Sodium alanine symporter
MIHOOLGA_02844 4.3e-56 ynfC
MIHOOLGA_02845 2.3e-12
MIHOOLGA_02846 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIHOOLGA_02847 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIHOOLGA_02848 8.6e-69 yccU S CoA-binding protein
MIHOOLGA_02849 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MIHOOLGA_02850 4.1e-49 yneR S Belongs to the HesB IscA family
MIHOOLGA_02851 1.7e-53 yneQ
MIHOOLGA_02852 2e-73 yneP S Thioesterase-like superfamily
MIHOOLGA_02853 3.9e-35 tlp S Belongs to the Tlp family
MIHOOLGA_02854 3.1e-08 sspN S Small acid-soluble spore protein N family
MIHOOLGA_02856 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIHOOLGA_02857 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIHOOLGA_02858 2.5e-14 sspO S Belongs to the SspO family
MIHOOLGA_02859 3.9e-19 sspP S Belongs to the SspP family
MIHOOLGA_02860 2.2e-63 hspX O Spore coat protein
MIHOOLGA_02861 4.2e-74 yneK S Protein of unknown function (DUF2621)
MIHOOLGA_02862 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MIHOOLGA_02863 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MIHOOLGA_02864 1.6e-126 ccdA O cytochrome c biogenesis protein
MIHOOLGA_02865 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MIHOOLGA_02866 1.8e-28 yneF S UPF0154 protein
MIHOOLGA_02867 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MIHOOLGA_02868 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIHOOLGA_02869 1.3e-32 ynzC S UPF0291 protein
MIHOOLGA_02870 1.7e-111 yneB L resolvase
MIHOOLGA_02871 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MIHOOLGA_02872 5.8e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIHOOLGA_02873 2.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MIHOOLGA_02874 1.7e-73 yndM S Protein of unknown function (DUF2512)
MIHOOLGA_02875 1.5e-135 yndL S Replication protein
MIHOOLGA_02877 3.4e-305 yndJ S YndJ-like protein
MIHOOLGA_02878 2.3e-89 yndH S Domain of unknown function (DUF4166)
MIHOOLGA_02879 1.1e-152 yndG S DoxX-like family
MIHOOLGA_02880 1.4e-86 gerLC S Spore germination protein
MIHOOLGA_02881 4.8e-277 gerAA EG Spore germination protein
MIHOOLGA_02884 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MIHOOLGA_02885 1.8e-71
MIHOOLGA_02886 3e-24 tatA U protein secretion
MIHOOLGA_02889 7.2e-130 S Domain of unknown function, YrpD
MIHOOLGA_02891 6.6e-164 S Thymidylate synthase
MIHOOLGA_02894 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MIHOOLGA_02895 2e-82 yncE S Protein of unknown function (DUF2691)
MIHOOLGA_02896 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIHOOLGA_02897 8.8e-254 iolT EGP Major facilitator Superfamily
MIHOOLGA_02898 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
MIHOOLGA_02899 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MIHOOLGA_02900 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MIHOOLGA_02901 2.8e-213 xylR GK ROK family
MIHOOLGA_02902 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MIHOOLGA_02903 3.9e-254 xynT G MFS/sugar transport protein
MIHOOLGA_02904 3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MIHOOLGA_02907 1.8e-113 ynaE S Domain of unknown function (DUF3885)
MIHOOLGA_02908 2.9e-98 ynaD J Acetyltransferase (GNAT) domain
MIHOOLGA_02910 6.4e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
MIHOOLGA_02911 8e-194 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_02912 1.5e-107 H Methionine biosynthesis protein MetW
MIHOOLGA_02913 3.4e-94 M Glycosyltransferase like family
MIHOOLGA_02914 5.4e-69 Q Collagen triple helix repeat (20 copies)
MIHOOLGA_02915 1.9e-30
MIHOOLGA_02916 2.1e-127 S Protein of unknown function (DUF1524)
MIHOOLGA_02917 4.1e-31 A Pre-toxin TG
MIHOOLGA_02918 6.6e-134 A Pre-toxin TG
MIHOOLGA_02919 2.2e-39
MIHOOLGA_02922 1.6e-13 S Domain of unknown function (DUF4917)
MIHOOLGA_02923 3e-14 S Domain of unknown function (DUF4917)
MIHOOLGA_02924 2.9e-76 ctsR K Belongs to the CtsR family
MIHOOLGA_02925 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MIHOOLGA_02926 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MIHOOLGA_02927 0.0 clpC O Belongs to the ClpA ClpB family
MIHOOLGA_02928 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIHOOLGA_02929 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MIHOOLGA_02930 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MIHOOLGA_02931 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIHOOLGA_02932 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIHOOLGA_02933 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIHOOLGA_02934 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MIHOOLGA_02935 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIHOOLGA_02936 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MIHOOLGA_02937 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIHOOLGA_02938 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MIHOOLGA_02939 4.4e-115 sigH K Belongs to the sigma-70 factor family
MIHOOLGA_02940 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIHOOLGA_02941 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MIHOOLGA_02942 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIHOOLGA_02943 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIHOOLGA_02944 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIHOOLGA_02945 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIHOOLGA_02946 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MIHOOLGA_02947 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIHOOLGA_02948 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIHOOLGA_02949 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MIHOOLGA_02950 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIHOOLGA_02951 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIHOOLGA_02952 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIHOOLGA_02953 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIHOOLGA_02954 2.6e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MIHOOLGA_02955 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MIHOOLGA_02956 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIHOOLGA_02957 3e-105 rplD J Forms part of the polypeptide exit tunnel
MIHOOLGA_02958 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIHOOLGA_02959 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIHOOLGA_02960 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIHOOLGA_02961 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIHOOLGA_02962 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIHOOLGA_02963 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIHOOLGA_02964 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MIHOOLGA_02965 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIHOOLGA_02966 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIHOOLGA_02967 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIHOOLGA_02968 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIHOOLGA_02969 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIHOOLGA_02970 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIHOOLGA_02971 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIHOOLGA_02972 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIHOOLGA_02973 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIHOOLGA_02974 1.9e-23 rpmD J Ribosomal protein L30
MIHOOLGA_02975 1.8e-72 rplO J binds to the 23S rRNA
MIHOOLGA_02976 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIHOOLGA_02977 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIHOOLGA_02978 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MIHOOLGA_02979 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIHOOLGA_02980 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MIHOOLGA_02981 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIHOOLGA_02982 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIHOOLGA_02983 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIHOOLGA_02984 3.6e-58 rplQ J Ribosomal protein L17
MIHOOLGA_02985 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIHOOLGA_02986 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIHOOLGA_02987 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIHOOLGA_02988 4.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIHOOLGA_02989 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIHOOLGA_02990 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MIHOOLGA_02991 2.4e-144 ybaJ Q Methyltransferase domain
MIHOOLGA_02992 3.8e-70 ybaK S Protein of unknown function (DUF2521)
MIHOOLGA_02993 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIHOOLGA_02994 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIHOOLGA_02995 1.2e-84 gerD
MIHOOLGA_02996 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MIHOOLGA_02997 4.3e-138 pdaB 3.5.1.104 G Polysaccharide deacetylase
MIHOOLGA_02998 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_02999 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIHOOLGA_03000 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIHOOLGA_03001 1.8e-37 yaaB S Domain of unknown function (DUF370)
MIHOOLGA_03002 4.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIHOOLGA_03003 2.4e-33 yaaA S S4 domain
MIHOOLGA_03004 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIHOOLGA_03005 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIHOOLGA_03006 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MIHOOLGA_03007 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIHOOLGA_03008 6.5e-108 jag S single-stranded nucleic acid binding R3H
MIHOOLGA_03009 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIHOOLGA_03010 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MIHOOLGA_03011 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MIHOOLGA_03012 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MIHOOLGA_03013 7.4e-74 S Bacterial PH domain
MIHOOLGA_03014 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MIHOOLGA_03015 2.1e-149 spo0J K Belongs to the ParB family
MIHOOLGA_03016 1.6e-111 yyaC S Sporulation protein YyaC
MIHOOLGA_03017 1.8e-176 yyaD S Membrane
MIHOOLGA_03018 2.3e-33 yyzM S protein conserved in bacteria
MIHOOLGA_03019 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIHOOLGA_03020 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIHOOLGA_03021 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MIHOOLGA_03022 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MIHOOLGA_03023 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIHOOLGA_03024 6.4e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MIHOOLGA_03025 2.3e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MIHOOLGA_03026 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_03027 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MIHOOLGA_03028 3e-243 EGP Major facilitator superfamily
MIHOOLGA_03029 8e-168 yyaK S CAAX protease self-immunity
MIHOOLGA_03030 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MIHOOLGA_03031 2e-82 yosT L Bacterial transcription activator, effector binding domain
MIHOOLGA_03032 5e-22 yyaR K acetyltransferase
MIHOOLGA_03033 5e-265 flp V Beta-lactamase
MIHOOLGA_03034 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MIHOOLGA_03039 1.9e-43 yddA
MIHOOLGA_03042 1.4e-15 yddB S Conjugative transposon protein TcpC
MIHOOLGA_03043 1.2e-15 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MIHOOLGA_03044 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
MIHOOLGA_03045 2.3e-65 yyaQ S YjbR
MIHOOLGA_03046 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
MIHOOLGA_03047 2.5e-96 yyaS S Membrane
MIHOOLGA_03048 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
MIHOOLGA_03049 5.6e-77 yybA 2.3.1.57 K transcriptional
MIHOOLGA_03050 1.1e-126 S Metallo-beta-lactamase superfamily
MIHOOLGA_03051 2.8e-74 yybC
MIHOOLGA_03052 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
MIHOOLGA_03053 1.1e-164 yybE K Transcriptional regulator
MIHOOLGA_03054 1.9e-212 ynfM EGP Major facilitator Superfamily
MIHOOLGA_03055 8.7e-99 yybG S Pentapeptide repeat-containing protein
MIHOOLGA_03056 2.9e-66 yybH S SnoaL-like domain
MIHOOLGA_03057 1.6e-124
MIHOOLGA_03058 4.8e-110 K TipAS antibiotic-recognition domain
MIHOOLGA_03059 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MIHOOLGA_03061 1.5e-58
MIHOOLGA_03062 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MIHOOLGA_03063 1.7e-66 ydeP3 K Transcriptional regulator
MIHOOLGA_03064 3.3e-83 cotF M Spore coat protein
MIHOOLGA_03066 8.3e-160 yybS S membrane
MIHOOLGA_03067 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MIHOOLGA_03068 2.2e-73 rplI J binds to the 23S rRNA
MIHOOLGA_03069 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MIHOOLGA_03070 8.4e-221 yeaN P COG2807 Cyanate permease
MIHOOLGA_03071 1.9e-15 yycC K YycC-like protein
MIHOOLGA_03073 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MIHOOLGA_03074 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MIHOOLGA_03075 2e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_03076 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIHOOLGA_03081 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_03082 0.0 vicK 2.7.13.3 T Histidine kinase
MIHOOLGA_03083 2.9e-257 yycH S protein conserved in bacteria
MIHOOLGA_03084 1.8e-153 yycI S protein conserved in bacteria
MIHOOLGA_03085 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MIHOOLGA_03086 3.3e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIHOOLGA_03087 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MIHOOLGA_03088 1.5e-40 sdpR K transcriptional
MIHOOLGA_03089 6.3e-58 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MIHOOLGA_03090 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MIHOOLGA_03091 7.2e-256 rocE E amino acid
MIHOOLGA_03092 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MIHOOLGA_03094 2.4e-174 S aspartate phosphatase
MIHOOLGA_03095 3.8e-84 yycN 2.3.1.128 K Acetyltransferase
MIHOOLGA_03096 6.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MIHOOLGA_03097 1.1e-206 yycP
MIHOOLGA_03098 2.6e-31 yycQ S Protein of unknown function (DUF2651)
MIHOOLGA_03100 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIHOOLGA_03101 1.4e-66
MIHOOLGA_03102 1.1e-09 S YyzF-like protein
MIHOOLGA_03103 2.9e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIHOOLGA_03104 1.3e-265 L helicase superfamily c-terminal domain
MIHOOLGA_03105 3.8e-85 S Domain of unknown function (DUF1837)
MIHOOLGA_03106 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MIHOOLGA_03107 2.3e-11
MIHOOLGA_03108 1.7e-184 S Radical SAM superfamily
MIHOOLGA_03109 1.9e-133 yydH O Peptidase M50
MIHOOLGA_03110 5.4e-110 prrC P ABC transporter
MIHOOLGA_03111 3.3e-119 S ABC-2 family transporter protein
MIHOOLGA_03112 7.1e-11
MIHOOLGA_03113 2.3e-125 yydK K Transcriptional regulator
MIHOOLGA_03114 2.2e-19 bglF G phosphotransferase system
MIHOOLGA_03115 9.2e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIHOOLGA_03116 3.8e-287 ahpF O Alkyl hydroperoxide reductase
MIHOOLGA_03117 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MIHOOLGA_03118 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIHOOLGA_03119 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
MIHOOLGA_03120 1e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MIHOOLGA_03121 2.8e-126 gntR K transcriptional
MIHOOLGA_03122 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MIHOOLGA_03123 1.7e-190 yxaB GM Polysaccharide pyruvyl transferase
MIHOOLGA_03124 1.3e-117 yxaC M effector of murein hydrolase
MIHOOLGA_03125 4.4e-43 S LrgA family
MIHOOLGA_03126 1.3e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_03127 5.6e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03128 2.1e-100 yxaF K Transcriptional regulator
MIHOOLGA_03129 7.1e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
MIHOOLGA_03130 8.7e-226 P Protein of unknown function (DUF418)
MIHOOLGA_03131 1.4e-75 yxaI S membrane protein domain
MIHOOLGA_03132 4.3e-63 S Family of unknown function (DUF5391)
MIHOOLGA_03133 3.7e-91 S PQQ-like domain
MIHOOLGA_03134 1.1e-20 yxaI S membrane protein domain
MIHOOLGA_03135 3.4e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MIHOOLGA_03136 1.8e-209 yxbF K Bacterial regulatory proteins, tetR family
MIHOOLGA_03137 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_03139 0.0 htpG O Molecular chaperone. Has ATPase activity
MIHOOLGA_03140 1.5e-245 csbC EGP Major facilitator Superfamily
MIHOOLGA_03141 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MIHOOLGA_03143 4.1e-175 iolS C Aldo keto reductase
MIHOOLGA_03144 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MIHOOLGA_03145 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIHOOLGA_03146 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MIHOOLGA_03147 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MIHOOLGA_03148 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MIHOOLGA_03149 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MIHOOLGA_03150 9.7e-110 iolF EGP Major facilitator Superfamily
MIHOOLGA_03151 2.1e-106 iolF EGP Major facilitator Superfamily
MIHOOLGA_03152 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MIHOOLGA_03153 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MIHOOLGA_03154 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MIHOOLGA_03155 2.7e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MIHOOLGA_03156 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_03157 4e-181 T PhoQ Sensor
MIHOOLGA_03158 9.4e-141 yxdL V ABC transporter, ATP-binding protein
MIHOOLGA_03159 0.0 yxdM V ABC transporter (permease)
MIHOOLGA_03160 3.4e-58 yxeA S Protein of unknown function (DUF1093)
MIHOOLGA_03161 6e-177 fhuD P ABC transporter
MIHOOLGA_03162 8.5e-69
MIHOOLGA_03163 5.6e-16 yxeD
MIHOOLGA_03164 1.2e-16 yxeE
MIHOOLGA_03167 1.8e-150 yidA S hydrolases of the HAD superfamily
MIHOOLGA_03168 6.9e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MIHOOLGA_03170 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_03171 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_03172 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MIHOOLGA_03173 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MIHOOLGA_03174 3.8e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MIHOOLGA_03175 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
MIHOOLGA_03176 2.3e-251 yxeQ S MmgE/PrpD family
MIHOOLGA_03177 1.2e-194 eutH E Ethanolamine utilisation protein, EutH
MIHOOLGA_03178 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MIHOOLGA_03179 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIHOOLGA_03180 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MIHOOLGA_03181 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIHOOLGA_03182 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MIHOOLGA_03183 2.2e-249 lysP E amino acid
MIHOOLGA_03184 9.8e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MIHOOLGA_03185 5.3e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MIHOOLGA_03186 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIHOOLGA_03187 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
MIHOOLGA_03188 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MIHOOLGA_03189 1e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MIHOOLGA_03190 4.6e-21 S Domain of unknown function (DUF5082)
MIHOOLGA_03191 1.4e-38 yxiC S Family of unknown function (DUF5344)
MIHOOLGA_03192 1.3e-131 S nuclease activity
MIHOOLGA_03193 3.3e-32
MIHOOLGA_03194 7e-304 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_03195 1.1e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIHOOLGA_03196 1.2e-71 yxiE T Belongs to the universal stress protein A family
MIHOOLGA_03197 1.4e-122 1.14.11.45 E 2OG-Fe dioxygenase
MIHOOLGA_03198 7.4e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_03199 4.8e-163 yxxF EG EamA-like transporter family
MIHOOLGA_03200 0.0 wapA M COG3209 Rhs family protein
MIHOOLGA_03201 7e-55
MIHOOLGA_03203 3.4e-127
MIHOOLGA_03204 5.2e-93 S Protein of unknown function (DUF4240)
MIHOOLGA_03205 8.4e-76
MIHOOLGA_03206 7.5e-51
MIHOOLGA_03207 4.8e-67 yxiG
MIHOOLGA_03208 1.3e-51 yxxG
MIHOOLGA_03209 1.9e-38 S Protein of unknown function (DUF2750)
MIHOOLGA_03210 4.3e-14 yxiG
MIHOOLGA_03211 8.3e-13 yxiG
MIHOOLGA_03212 3.8e-135
MIHOOLGA_03213 7.9e-85 yxiI S Protein of unknown function (DUF2716)
MIHOOLGA_03214 7.7e-43 yxiJ S YxiJ-like protein
MIHOOLGA_03217 2.5e-60 S Protein of unknown function (DUF2812)
MIHOOLGA_03218 4.2e-53 padR K Transcriptional regulator PadR-like family
MIHOOLGA_03219 5.2e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MIHOOLGA_03220 3.9e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MIHOOLGA_03221 1.1e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
MIHOOLGA_03222 6.8e-111
MIHOOLGA_03223 8.3e-151 licT K transcriptional antiterminator
MIHOOLGA_03224 3.3e-143 exoK GH16 M licheninase activity
MIHOOLGA_03225 6.6e-224 citH C Citrate transporter
MIHOOLGA_03226 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MIHOOLGA_03227 5.1e-47 yxiS
MIHOOLGA_03228 2e-102 T Domain of unknown function (DUF4163)
MIHOOLGA_03229 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIHOOLGA_03230 3.3e-155 rlmA 2.1.1.187 Q Methyltransferase domain
MIHOOLGA_03231 4.4e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MIHOOLGA_03232 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIHOOLGA_03233 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MIHOOLGA_03234 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MIHOOLGA_03235 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
MIHOOLGA_03236 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
MIHOOLGA_03237 1e-84 yxjI S LURP-one-related
MIHOOLGA_03240 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MIHOOLGA_03241 2.1e-112 K helix_turn_helix, Lux Regulon
MIHOOLGA_03242 8.3e-192 yxjM T Signal transduction histidine kinase
MIHOOLGA_03243 5.9e-77 S Protein of unknown function (DUF1453)
MIHOOLGA_03244 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MIHOOLGA_03245 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MIHOOLGA_03246 9.1e-270 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIHOOLGA_03247 4.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
MIHOOLGA_03248 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MIHOOLGA_03249 5.6e-155 yxkH G Polysaccharide deacetylase
MIHOOLGA_03250 0.0 3.4.24.84 O Peptidase family M48
MIHOOLGA_03251 5.5e-229 cimH C COG3493 Na citrate symporter
MIHOOLGA_03252 2.2e-268 cydA 1.10.3.14 C oxidase, subunit
MIHOOLGA_03253 3.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MIHOOLGA_03254 1.7e-310 cydD V ATP-binding
MIHOOLGA_03255 0.0 cydD V ATP-binding protein
MIHOOLGA_03256 1.4e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIHOOLGA_03257 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MIHOOLGA_03258 1.1e-84 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MIHOOLGA_03259 3.9e-48 yxlC S Family of unknown function (DUF5345)
MIHOOLGA_03260 1.4e-30
MIHOOLGA_03261 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MIHOOLGA_03262 2.6e-166 yxlF V ABC transporter, ATP-binding protein
MIHOOLGA_03263 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIHOOLGA_03264 3.5e-211 yxlH EGP Major facilitator Superfamily
MIHOOLGA_03265 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIHOOLGA_03266 3.8e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MIHOOLGA_03267 1.1e-19 yxzF
MIHOOLGA_03268 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MIHOOLGA_03269 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MIHOOLGA_03270 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIHOOLGA_03271 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIHOOLGA_03272 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIHOOLGA_03273 5.9e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MIHOOLGA_03274 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03275 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MIHOOLGA_03276 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_03277 3.6e-232 dltB M membrane protein involved in D-alanine export
MIHOOLGA_03278 2.8e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_03279 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MIHOOLGA_03280 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MIHOOLGA_03281 5.2e-130 ynfM EGP Major facilitator Superfamily
MIHOOLGA_03282 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MIHOOLGA_03283 1.4e-92 K Helix-turn-helix XRE-family like proteins
MIHOOLGA_03284 2.8e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MIHOOLGA_03285 3.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIHOOLGA_03286 2.3e-87 ywaE K Transcriptional regulator
MIHOOLGA_03287 8.2e-123 ywaF S Integral membrane protein
MIHOOLGA_03288 2.9e-167 gspA M General stress
MIHOOLGA_03289 4e-153 sacY K transcriptional antiterminator
MIHOOLGA_03290 3.4e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_03291 6.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
MIHOOLGA_03292 9.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIHOOLGA_03293 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MIHOOLGA_03294 1.2e-219 ywbD 2.1.1.191 J Methyltransferase
MIHOOLGA_03295 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MIHOOLGA_03296 1.9e-170 ywbF EGP Major facilitator Superfamily
MIHOOLGA_03297 4.5e-25 ywbF EGP Major facilitator Superfamily
MIHOOLGA_03298 2.3e-111 ywbG M effector of murein hydrolase
MIHOOLGA_03299 2.2e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MIHOOLGA_03300 1.6e-152 ywbI K Transcriptional regulator
MIHOOLGA_03301 2.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIHOOLGA_03302 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MIHOOLGA_03303 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
MIHOOLGA_03304 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
MIHOOLGA_03305 1.2e-222 ywbN P Dyp-type peroxidase family protein
MIHOOLGA_03306 7.9e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MIHOOLGA_03307 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIHOOLGA_03308 9.8e-49 ywcB S Protein of unknown function, DUF485
MIHOOLGA_03310 2.2e-122 ywcC K transcriptional regulator
MIHOOLGA_03311 9.5e-60 gtcA S GtrA-like protein
MIHOOLGA_03312 6.9e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIHOOLGA_03313 8e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MIHOOLGA_03314 1e-35 ywzA S membrane
MIHOOLGA_03315 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MIHOOLGA_03316 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIHOOLGA_03317 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIHOOLGA_03318 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIHOOLGA_03319 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MIHOOLGA_03320 4e-204 S Acetyltransferase
MIHOOLGA_03321 1.9e-188 rodA D Belongs to the SEDS family
MIHOOLGA_03322 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MIHOOLGA_03323 4.7e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_03324 0.0 vpr O Belongs to the peptidase S8 family
MIHOOLGA_03326 7e-150 sacT K transcriptional antiterminator
MIHOOLGA_03327 5.7e-138 focA P Formate/nitrite transporter
MIHOOLGA_03328 7.6e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIHOOLGA_03329 4.4e-285 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MIHOOLGA_03330 2e-28 ywdA
MIHOOLGA_03331 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIHOOLGA_03332 1.3e-57 pex K Transcriptional regulator PadR-like family
MIHOOLGA_03333 8.9e-113 ywdD
MIHOOLGA_03335 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MIHOOLGA_03336 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIHOOLGA_03337 1e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MIHOOLGA_03338 7.7e-49 ywdI S Family of unknown function (DUF5327)
MIHOOLGA_03339 3.7e-238 ywdJ F Xanthine uracil
MIHOOLGA_03340 4.3e-59 ywdK S small membrane protein
MIHOOLGA_03341 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MIHOOLGA_03342 2e-143 spsA M Spore Coat
MIHOOLGA_03343 8.9e-267 spsB M Capsule polysaccharide biosynthesis protein
MIHOOLGA_03344 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
MIHOOLGA_03345 5.8e-163 spsD 2.3.1.210 K Spore Coat
MIHOOLGA_03346 3.5e-213 spsE 2.5.1.56 M acid synthase
MIHOOLGA_03347 3.1e-130 spsF M Spore Coat
MIHOOLGA_03348 1.2e-188 spsG M Spore Coat
MIHOOLGA_03349 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIHOOLGA_03350 5.1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIHOOLGA_03351 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIHOOLGA_03352 1.3e-86 spsL 5.1.3.13 M Spore Coat
MIHOOLGA_03353 1.2e-77
MIHOOLGA_03354 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIHOOLGA_03355 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MIHOOLGA_03356 0.0 rocB E arginine degradation protein
MIHOOLGA_03357 1.4e-248 lysP E amino acid
MIHOOLGA_03358 1.7e-205 ywfA EGP Major facilitator Superfamily
MIHOOLGA_03359 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MIHOOLGA_03360 3.7e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MIHOOLGA_03361 2.8e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_03362 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MIHOOLGA_03363 5.6e-209 bacE EGP Major facilitator Superfamily
MIHOOLGA_03364 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
MIHOOLGA_03365 3.2e-136 IQ Enoyl-(Acyl carrier protein) reductase
MIHOOLGA_03366 3.3e-146 ywfI C May function as heme-dependent peroxidase
MIHOOLGA_03367 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MIHOOLGA_03368 1.1e-156 cysL K Transcriptional regulator
MIHOOLGA_03369 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MIHOOLGA_03370 1.4e-156 ywfM EG EamA-like transporter family
MIHOOLGA_03371 5.1e-110 rsfA_1
MIHOOLGA_03372 3.1e-36 ywzC S Belongs to the UPF0741 family
MIHOOLGA_03373 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MIHOOLGA_03374 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
MIHOOLGA_03375 1.4e-78 yffB K Transcriptional regulator
MIHOOLGA_03376 6.8e-238 mmr U Major Facilitator Superfamily
MIHOOLGA_03377 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIHOOLGA_03378 9.5e-71 ywhA K Transcriptional regulator
MIHOOLGA_03379 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MIHOOLGA_03380 5.1e-119 ywhC S Peptidase family M50
MIHOOLGA_03381 5.2e-95 ywhD S YwhD family
MIHOOLGA_03382 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIHOOLGA_03383 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIHOOLGA_03384 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MIHOOLGA_03385 2.2e-62 ywhH S Aminoacyl-tRNA editing domain
MIHOOLGA_03387 2.6e-78 S aspartate phosphatase
MIHOOLGA_03388 2.3e-190 ywhK CO amine dehydrogenase activity
MIHOOLGA_03389 4e-243 ywhL CO amine dehydrogenase activity
MIHOOLGA_03391 1e-245 L Peptidase, M16
MIHOOLGA_03392 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
MIHOOLGA_03393 1.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MIHOOLGA_03394 2.8e-131 cbiO V ABC transporter
MIHOOLGA_03396 1.4e-269 C Fe-S oxidoreductases
MIHOOLGA_03397 1e-07 S Bacteriocin subtilosin A
MIHOOLGA_03398 4.7e-73 ywiB S protein conserved in bacteria
MIHOOLGA_03399 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MIHOOLGA_03400 2.5e-212 narK P COG2223 Nitrate nitrite transporter
MIHOOLGA_03401 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MIHOOLGA_03402 1.7e-139 ywiC S YwiC-like protein
MIHOOLGA_03403 7e-86 arfM T cyclic nucleotide binding
MIHOOLGA_03404 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIHOOLGA_03405 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
MIHOOLGA_03406 3.6e-94 narJ 1.7.5.1 C nitrate reductase
MIHOOLGA_03407 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MIHOOLGA_03408 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIHOOLGA_03409 3.8e-309 ywjA V ABC transporter
MIHOOLGA_03410 5.3e-95 ywjB H RibD C-terminal domain
MIHOOLGA_03411 2.7e-42 ywjC
MIHOOLGA_03412 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MIHOOLGA_03413 2.2e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MIHOOLGA_03414 0.0 fadF C COG0247 Fe-S oxidoreductase
MIHOOLGA_03415 9.7e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MIHOOLGA_03416 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MIHOOLGA_03417 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIHOOLGA_03418 2.3e-90 ywjG S Domain of unknown function (DUF2529)
MIHOOLGA_03419 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MIHOOLGA_03420 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MIHOOLGA_03421 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIHOOLGA_03422 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIHOOLGA_03423 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MIHOOLGA_03424 6.2e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIHOOLGA_03425 1.1e-32 rpmE J Binds the 23S rRNA
MIHOOLGA_03426 5.4e-104 tdk 2.7.1.21 F thymidine kinase
MIHOOLGA_03427 0.0 sfcA 1.1.1.38 C malic enzyme
MIHOOLGA_03428 8.6e-160 ywkB S Membrane transport protein
MIHOOLGA_03429 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MIHOOLGA_03430 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_03431 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIHOOLGA_03432 2.6e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIHOOLGA_03434 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MIHOOLGA_03435 6.1e-112 spoIIR S stage II sporulation protein R
MIHOOLGA_03436 1.4e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MIHOOLGA_03437 3.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MIHOOLGA_03438 3.8e-91 mntP P Probably functions as a manganese efflux pump
MIHOOLGA_03439 1.8e-75 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIHOOLGA_03440 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MIHOOLGA_03441 3.6e-94 ywlG S Belongs to the UPF0340 family
MIHOOLGA_03442 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIHOOLGA_03443 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIHOOLGA_03444 2.5e-62 atpI S ATP synthase
MIHOOLGA_03445 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MIHOOLGA_03446 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIHOOLGA_03447 1.6e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIHOOLGA_03448 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIHOOLGA_03449 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIHOOLGA_03450 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIHOOLGA_03451 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIHOOLGA_03452 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MIHOOLGA_03453 4.8e-87 ywmA
MIHOOLGA_03454 1.3e-32 ywzB S membrane
MIHOOLGA_03455 3.7e-134 ywmB S TATA-box binding
MIHOOLGA_03456 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIHOOLGA_03457 6e-175 spoIID D Stage II sporulation protein D
MIHOOLGA_03458 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MIHOOLGA_03459 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MIHOOLGA_03461 7.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIHOOLGA_03462 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIHOOLGA_03463 4.6e-104 S response regulator aspartate phosphatase
MIHOOLGA_03465 3.8e-84 ywmF S Peptidase M50
MIHOOLGA_03466 3.8e-11 csbD K CsbD-like
MIHOOLGA_03467 5e-22 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MIHOOLGA_03468 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MIHOOLGA_03469 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MIHOOLGA_03470 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MIHOOLGA_03471 1.7e-64 ywnA K Transcriptional regulator
MIHOOLGA_03472 3.1e-113 ywnB S NAD(P)H-binding
MIHOOLGA_03473 2.6e-59 ywnC S Family of unknown function (DUF5362)
MIHOOLGA_03474 5e-142 mta K transcriptional
MIHOOLGA_03475 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIHOOLGA_03476 2.2e-70 ywnF S Family of unknown function (DUF5392)
MIHOOLGA_03477 8.9e-10 ywnC S Family of unknown function (DUF5362)
MIHOOLGA_03478 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MIHOOLGA_03479 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MIHOOLGA_03480 3.5e-73 ywnJ S VanZ like family
MIHOOLGA_03481 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MIHOOLGA_03482 1.6e-58 nrgB K Belongs to the P(II) protein family
MIHOOLGA_03483 4.3e-225 amt P Ammonium transporter
MIHOOLGA_03484 4.8e-76
MIHOOLGA_03485 7.5e-103 phzA Q Isochorismatase family
MIHOOLGA_03486 7e-240 ywoD EGP Major facilitator superfamily
MIHOOLGA_03487 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MIHOOLGA_03488 2.8e-231 ywoF P Right handed beta helix region
MIHOOLGA_03489 3.9e-210 ywoG EGP Major facilitator Superfamily
MIHOOLGA_03490 2.1e-70 ywoH K COG1846 Transcriptional regulators
MIHOOLGA_03491 3e-44 spoIIID K Stage III sporulation protein D
MIHOOLGA_03492 3.5e-180 mbl D Rod shape-determining protein
MIHOOLGA_03493 5.8e-125 flhO N flagellar basal body
MIHOOLGA_03494 2.6e-141 flhP N flagellar basal body
MIHOOLGA_03495 6.3e-196 S aspartate phosphatase
MIHOOLGA_03496 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MIHOOLGA_03497 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MIHOOLGA_03498 7e-153 ywpD T Histidine kinase
MIHOOLGA_03499 1.2e-49 srtA 3.4.22.70 M Sortase family
MIHOOLGA_03500 1.1e-66 ywpF S YwpF-like protein
MIHOOLGA_03501 1.3e-66 ywpG
MIHOOLGA_03502 3.7e-57 ssbB L Single-stranded DNA-binding protein
MIHOOLGA_03503 1.5e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
MIHOOLGA_03504 1.5e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MIHOOLGA_03505 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIHOOLGA_03506 2.1e-307 ywqB S SWIM zinc finger
MIHOOLGA_03507 1.2e-17
MIHOOLGA_03508 2e-116 ywqC M biosynthesis protein
MIHOOLGA_03509 4.5e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MIHOOLGA_03510 6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MIHOOLGA_03511 2.6e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIHOOLGA_03512 3.2e-152 ywqG S Domain of unknown function (DUF1963)
MIHOOLGA_03513 1.7e-19 S Domain of unknown function (DUF5082)
MIHOOLGA_03514 3.1e-38 ywqI S Family of unknown function (DUF5344)
MIHOOLGA_03515 7.4e-251 ywqJ S Pre-toxin TG
MIHOOLGA_03516 3.2e-68 S Immunity protein Imm6
MIHOOLGA_03517 1.4e-49
MIHOOLGA_03519 1.5e-82
MIHOOLGA_03520 5.9e-72
MIHOOLGA_03521 5.1e-125 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MIHOOLGA_03522 1.4e-161 K Transcriptional regulator
MIHOOLGA_03523 3.3e-100 ywqN S NAD(P)H-dependent
MIHOOLGA_03524 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
MIHOOLGA_03525 4.6e-103 ywrB P Chromate transporter
MIHOOLGA_03526 8e-82 ywrC K Transcriptional regulator
MIHOOLGA_03527 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MIHOOLGA_03528 5e-54 S Domain of unknown function (DUF4181)
MIHOOLGA_03529 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIHOOLGA_03530 3.7e-12
MIHOOLGA_03531 3.5e-210 cotH M Spore Coat
MIHOOLGA_03532 7.6e-131 cotB
MIHOOLGA_03533 1.1e-124 ywrJ
MIHOOLGA_03534 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIHOOLGA_03535 1.1e-169 alsR K LysR substrate binding domain
MIHOOLGA_03536 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MIHOOLGA_03537 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MIHOOLGA_03538 6.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MIHOOLGA_03539 8e-48 ywsA S Protein of unknown function (DUF3892)
MIHOOLGA_03540 1.2e-91 batE T Sh3 type 3 domain protein
MIHOOLGA_03541 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MIHOOLGA_03542 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MIHOOLGA_03543 6.2e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MIHOOLGA_03544 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MIHOOLGA_03545 2.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIHOOLGA_03546 9.3e-178 rbsR K transcriptional
MIHOOLGA_03547 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MIHOOLGA_03548 8.6e-70 pgsC S biosynthesis protein
MIHOOLGA_03549 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MIHOOLGA_03550 1.4e-20 ywtC
MIHOOLGA_03551 2e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MIHOOLGA_03552 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MIHOOLGA_03553 1.9e-138 ywtF K Transcriptional regulator
MIHOOLGA_03554 2.8e-101 ywtG EGP Major facilitator Superfamily
MIHOOLGA_03555 8.7e-131 ywtG EGP Major facilitator Superfamily
MIHOOLGA_03556 1.2e-197 gerAC S Spore germination protein
MIHOOLGA_03557 5.6e-187 gerBB E Spore germination protein
MIHOOLGA_03558 1e-244 gerBA EG Spore germination protein
MIHOOLGA_03559 2.4e-186 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MIHOOLGA_03560 5.2e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MIHOOLGA_03561 2.3e-191 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MIHOOLGA_03562 1.5e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MIHOOLGA_03563 4.9e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MIHOOLGA_03564 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MIHOOLGA_03565 1.3e-282 tagF2 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIHOOLGA_03566 1.4e-13
MIHOOLGA_03567 1.8e-134 tagG GM Transport permease protein
MIHOOLGA_03568 1.1e-159 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MIHOOLGA_03569 6.1e-10 L COG2963 Transposase and inactivated derivatives
MIHOOLGA_03570 2.1e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIHOOLGA_03571 1.9e-206 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MIHOOLGA_03572 5e-17 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MIHOOLGA_03573 2.9e-11
MIHOOLGA_03574 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MIHOOLGA_03575 2.3e-260 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIHOOLGA_03576 4.7e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MIHOOLGA_03577 1.3e-231 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_03578 8.5e-202 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MIHOOLGA_03579 8.4e-238 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIHOOLGA_03581 1.2e-242 tuaE M Teichuronic acid biosynthesis protein
MIHOOLGA_03582 5e-106 tuaF M protein involved in exopolysaccharide biosynthesis
MIHOOLGA_03583 4.4e-135 tuaG GT2 M Glycosyltransferase like family 2
MIHOOLGA_03584 2.1e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MIHOOLGA_03585 3.4e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MIHOOLGA_03586 1e-13
MIHOOLGA_03587 8.7e-79 V ABC transporter, ATP-binding protein
MIHOOLGA_03588 6.6e-28 S CytoplasmicMembrane, score 9.99
MIHOOLGA_03590 7.7e-42 S Psort location CytoplasmicMembrane, score
MIHOOLGA_03594 1.3e-113 yvhJ K Transcriptional regulator
MIHOOLGA_03595 4.9e-106 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MIHOOLGA_03596 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MIHOOLGA_03597 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_03598 6.2e-154 degV S protein conserved in bacteria
MIHOOLGA_03599 1.1e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MIHOOLGA_03600 1.8e-44 comFB S Late competence development protein ComFB
MIHOOLGA_03601 1.2e-126 comFC S Phosphoribosyl transferase domain
MIHOOLGA_03602 7e-74 yvyF S flagellar protein
MIHOOLGA_03603 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
MIHOOLGA_03604 4.1e-78 flgN NOU FlgN protein
MIHOOLGA_03605 1.2e-264 flgK N flagellar hook-associated protein
MIHOOLGA_03606 7.8e-155 flgL N Belongs to the bacterial flagellin family
MIHOOLGA_03607 1.3e-49 yviE
MIHOOLGA_03608 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MIHOOLGA_03609 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MIHOOLGA_03610 1.5e-124 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIHOOLGA_03611 1.2e-55 flaG N flagellar protein FlaG
MIHOOLGA_03612 4.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MIHOOLGA_03613 6.5e-69 fliS N flagellar protein FliS
MIHOOLGA_03614 1.4e-08 fliT S bacterial-type flagellum organization
MIHOOLGA_03615 3e-50
MIHOOLGA_03616 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIHOOLGA_03617 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIHOOLGA_03618 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIHOOLGA_03619 2.1e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MIHOOLGA_03620 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
MIHOOLGA_03621 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MIHOOLGA_03622 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MIHOOLGA_03623 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MIHOOLGA_03624 5.3e-56 swrA S Swarming motility protein
MIHOOLGA_03625 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIHOOLGA_03626 9.6e-226 yvkA EGP Major facilitator Superfamily
MIHOOLGA_03627 7e-101 yvkB K Transcriptional regulator
MIHOOLGA_03628 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MIHOOLGA_03629 1.2e-30 csbA S protein conserved in bacteria
MIHOOLGA_03630 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIHOOLGA_03631 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIHOOLGA_03632 8e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIHOOLGA_03633 6.7e-34 yvkN
MIHOOLGA_03634 8e-49 yvlA
MIHOOLGA_03635 2.4e-166 yvlB S Putative adhesin
MIHOOLGA_03636 2.6e-26 pspB KT PspC domain
MIHOOLGA_03637 1.2e-50 yvlD S Membrane
MIHOOLGA_03638 2.7e-203 yvmA EGP Major facilitator Superfamily
MIHOOLGA_03639 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_03640 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MIHOOLGA_03641 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
MIHOOLGA_03642 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MIHOOLGA_03643 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MIHOOLGA_03644 1.8e-133 yvoA K transcriptional
MIHOOLGA_03645 4.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIHOOLGA_03646 2e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIHOOLGA_03647 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MIHOOLGA_03648 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIHOOLGA_03649 4.9e-160 yvoD P COG0370 Fe2 transport system protein B
MIHOOLGA_03650 9.4e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MIHOOLGA_03651 2.5e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MIHOOLGA_03652 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MIHOOLGA_03653 6.6e-139 yvpB NU protein conserved in bacteria
MIHOOLGA_03654 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MIHOOLGA_03655 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MIHOOLGA_03656 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIHOOLGA_03657 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MIHOOLGA_03658 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIHOOLGA_03659 6.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MIHOOLGA_03660 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIHOOLGA_03661 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MIHOOLGA_03662 2.2e-78
MIHOOLGA_03663 1.6e-253
MIHOOLGA_03665 0.0 msbA2 3.6.3.44 V ABC transporter
MIHOOLGA_03666 1.2e-277 S COG0457 FOG TPR repeat
MIHOOLGA_03667 1.1e-97 usp CBM50 M protein conserved in bacteria
MIHOOLGA_03668 3.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIHOOLGA_03669 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MIHOOLGA_03670 5.7e-166 rapZ S Displays ATPase and GTPase activities
MIHOOLGA_03671 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MIHOOLGA_03672 1.4e-170 whiA K May be required for sporulation
MIHOOLGA_03673 1.6e-36 crh G Phosphocarrier protein Chr
MIHOOLGA_03674 5.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MIHOOLGA_03675 3.3e-32
MIHOOLGA_03676 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_03677 4.4e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MIHOOLGA_03678 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MIHOOLGA_03679 0.0 yxdM V ABC transporter (permease)
MIHOOLGA_03680 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIHOOLGA_03681 1.3e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MIHOOLGA_03682 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MIHOOLGA_03683 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MIHOOLGA_03684 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MIHOOLGA_03685 8.8e-173 yvdE K Transcriptional regulator
MIHOOLGA_03686 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MIHOOLGA_03687 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MIHOOLGA_03688 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MIHOOLGA_03689 6.6e-148 malD P transport
MIHOOLGA_03690 6.5e-154 malA S Protein of unknown function (DUF1189)
MIHOOLGA_03691 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MIHOOLGA_03692 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MIHOOLGA_03693 2.3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MIHOOLGA_03694 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIHOOLGA_03696 1.2e-182 S Patatin-like phospholipase
MIHOOLGA_03697 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
MIHOOLGA_03698 1.1e-92 yvdQ S Protein of unknown function (DUF3231)
MIHOOLGA_03699 2.7e-49 sugE P Small Multidrug Resistance protein
MIHOOLGA_03700 6.7e-51 ykkC P Small Multidrug Resistance protein
MIHOOLGA_03701 7.4e-106 yvdT K Transcriptional regulator
MIHOOLGA_03702 1.8e-295 yveA E amino acid
MIHOOLGA_03703 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MIHOOLGA_03704 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MIHOOLGA_03705 1.1e-261 pbpE V Beta-lactamase
MIHOOLGA_03706 7.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MIHOOLGA_03707 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
MIHOOLGA_03708 4.6e-93 padC Q Phenolic acid decarboxylase
MIHOOLGA_03710 1.3e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MIHOOLGA_03711 2.8e-76 slr K transcriptional
MIHOOLGA_03712 2.6e-121 ywqC M biosynthesis protein
MIHOOLGA_03713 6.6e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MIHOOLGA_03714 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MIHOOLGA_03715 1.5e-219 epsD GT4 M Glycosyl transferase 4-like
MIHOOLGA_03716 7.8e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_03717 9.3e-217 epsF GT4 M Glycosyl transferases group 1
MIHOOLGA_03718 1.1e-206 epsG S EpsG family
MIHOOLGA_03719 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
MIHOOLGA_03720 2.4e-203 epsI GM pyruvyl transferase
MIHOOLGA_03721 3.5e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MIHOOLGA_03722 2e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_03723 5.7e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MIHOOLGA_03724 3.5e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MIHOOLGA_03725 4.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MIHOOLGA_03726 1e-184 yvfF GM Exopolysaccharide biosynthesis protein
MIHOOLGA_03727 1e-31 yvfG S YvfG protein
MIHOOLGA_03728 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MIHOOLGA_03729 2.8e-307 yvfH C L-lactate permease
MIHOOLGA_03730 1.7e-112 yvfI K COG2186 Transcriptional regulators
MIHOOLGA_03731 4e-184 lacR K Transcriptional regulator
MIHOOLGA_03732 1.3e-224 cycB G COG2182 Maltose-binding periplasmic proteins domains
MIHOOLGA_03733 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
MIHOOLGA_03734 7.2e-150 ganQ P transport
MIHOOLGA_03735 0.0 lacA 3.2.1.23 G beta-galactosidase
MIHOOLGA_03736 9.8e-252 galA 3.2.1.89 G arabinogalactan
MIHOOLGA_03737 1.4e-199 rsbU 3.1.3.3 T response regulator
MIHOOLGA_03738 9.8e-157 rsbQ S Alpha/beta hydrolase family
MIHOOLGA_03739 3.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MIHOOLGA_03740 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MIHOOLGA_03741 1.5e-195 desK 2.7.13.3 T Histidine kinase
MIHOOLGA_03742 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_03743 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIHOOLGA_03744 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MIHOOLGA_03745 4.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIHOOLGA_03746 1.1e-180 yvbX S Glycosyl hydrolase
MIHOOLGA_03747 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MIHOOLGA_03748 7.5e-150 yvbV EG EamA-like transporter family
MIHOOLGA_03749 1.1e-158 yvbU K Transcriptional regulator
MIHOOLGA_03750 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIHOOLGA_03751 5.5e-203 araR K transcriptional
MIHOOLGA_03752 1.6e-252 araE EGP Major facilitator Superfamily
MIHOOLGA_03753 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIHOOLGA_03754 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIHOOLGA_03755 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MIHOOLGA_03756 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIHOOLGA_03757 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MIHOOLGA_03758 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIHOOLGA_03759 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
MIHOOLGA_03760 0.0 tcaA S response to antibiotic
MIHOOLGA_03761 2.3e-122 exoY M Membrane
MIHOOLGA_03762 1.9e-112 yvbH S YvbH-like oligomerisation region
MIHOOLGA_03763 2.4e-102 yvbG U UPF0056 membrane protein
MIHOOLGA_03764 1.8e-96 yvbF K Belongs to the GbsR family
MIHOOLGA_03765 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIHOOLGA_03766 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIHOOLGA_03767 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MIHOOLGA_03768 4.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIHOOLGA_03769 7.4e-60 yvbF K Belongs to the GbsR family
MIHOOLGA_03770 1.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIHOOLGA_03771 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIHOOLGA_03772 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MIHOOLGA_03773 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIHOOLGA_03774 1.1e-218 NT chemotaxis protein
MIHOOLGA_03775 2.2e-54 yodB K transcriptional
MIHOOLGA_03776 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MIHOOLGA_03777 4e-69 K transcriptional
MIHOOLGA_03778 7.5e-36 yvzC K Transcriptional
MIHOOLGA_03779 1.8e-152 yvaM S Serine aminopeptidase, S33
MIHOOLGA_03780 2.4e-23 secG U Preprotein translocase subunit SecG
MIHOOLGA_03781 5.6e-143 est 3.1.1.1 S Carboxylesterase
MIHOOLGA_03782 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MIHOOLGA_03783 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MIHOOLGA_03785 7.7e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03786 3.9e-99 K Bacterial regulatory proteins, tetR family
MIHOOLGA_03787 6.9e-54 yvaE P Small Multidrug Resistance protein
MIHOOLGA_03788 9.1e-71 yvaD S Family of unknown function (DUF5360)
MIHOOLGA_03789 0.0 yvaC S Fusaric acid resistance protein-like
MIHOOLGA_03790 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIHOOLGA_03791 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
MIHOOLGA_03792 2.2e-48 csoR S transcriptional
MIHOOLGA_03793 1.5e-29 copZ P Copper resistance protein CopZ
MIHOOLGA_03794 0.0 copA 3.6.3.54 P P-type ATPase
MIHOOLGA_03795 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIHOOLGA_03796 2.7e-104 bdbD O Thioredoxin
MIHOOLGA_03797 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MIHOOLGA_03798 4.1e-107 yvgT S membrane
MIHOOLGA_03799 0.0 helD 3.6.4.12 L DNA helicase
MIHOOLGA_03800 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIHOOLGA_03801 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MIHOOLGA_03802 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MIHOOLGA_03803 5.4e-86 yvgO
MIHOOLGA_03804 5.9e-157 yvgN S reductase
MIHOOLGA_03805 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
MIHOOLGA_03806 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MIHOOLGA_03807 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MIHOOLGA_03808 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIHOOLGA_03809 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MIHOOLGA_03810 6.5e-16 S Small spore protein J (Spore_SspJ)
MIHOOLGA_03811 4.9e-236 yvsH E Arginine ornithine antiporter
MIHOOLGA_03812 9e-178 fhuD P ABC transporter
MIHOOLGA_03813 2.3e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_03814 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_03815 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
MIHOOLGA_03816 1.8e-175 M Efflux transporter rnd family, mfp subunit
MIHOOLGA_03817 1.6e-123 macB V ABC transporter, ATP-binding protein
MIHOOLGA_03818 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIHOOLGA_03819 1.3e-64 yvrL S Regulatory protein YrvL
MIHOOLGA_03820 2.3e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
MIHOOLGA_03821 2.4e-19 S YvrJ protein family
MIHOOLGA_03822 2.1e-97 yvrI K RNA polymerase
MIHOOLGA_03823 3.6e-22
MIHOOLGA_03824 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_03825 0.0 T PhoQ Sensor
MIHOOLGA_03826 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MIHOOLGA_03827 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03828 1.5e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MIHOOLGA_03829 4.7e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIHOOLGA_03830 2.7e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MIHOOLGA_03831 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
MIHOOLGA_03832 7e-226 yvqJ EGP Major facilitator Superfamily
MIHOOLGA_03833 5.6e-62 liaI S membrane
MIHOOLGA_03834 1.2e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MIHOOLGA_03835 4.6e-120 liaG S Putative adhesin
MIHOOLGA_03836 3e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MIHOOLGA_03837 7.9e-186 vraS 2.7.13.3 T Histidine kinase
MIHOOLGA_03838 3.9e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_03839 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
MIHOOLGA_03840 2.2e-196 gerAB E Spore germination protein
MIHOOLGA_03841 1.4e-246 gerAA EG Spore germination protein
MIHOOLGA_03842 3.9e-24 S Protein of unknown function (DUF3970)
MIHOOLGA_03843 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MIHOOLGA_03844 4.3e-158 yuxN K Transcriptional regulator
MIHOOLGA_03845 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MIHOOLGA_03846 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIHOOLGA_03847 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIHOOLGA_03848 1.2e-79 dps P Ferritin-like domain
MIHOOLGA_03849 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03850 1e-299 pepF2 E COG1164 Oligoendopeptidase F
MIHOOLGA_03851 2.5e-66 S YusW-like protein
MIHOOLGA_03852 3.9e-153 yusV 3.6.3.34 HP ABC transporter
MIHOOLGA_03853 1.1e-46 yusU S Protein of unknown function (DUF2573)
MIHOOLGA_03854 2.2e-157 yusT K LysR substrate binding domain
MIHOOLGA_03855 1.9e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03856 2.7e-64 yusQ S Tautomerase enzyme
MIHOOLGA_03857 3.6e-291 yusP P Major facilitator superfamily
MIHOOLGA_03858 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MIHOOLGA_03859 5.4e-53 yusN M Coat F domain
MIHOOLGA_03860 5.1e-40
MIHOOLGA_03861 1.9e-164 fadM E Proline dehydrogenase
MIHOOLGA_03862 8.1e-09 S YuzL-like protein
MIHOOLGA_03863 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MIHOOLGA_03864 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MIHOOLGA_03865 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MIHOOLGA_03866 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MIHOOLGA_03867 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MIHOOLGA_03868 5.4e-39 yusG S Protein of unknown function (DUF2553)
MIHOOLGA_03869 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MIHOOLGA_03870 1.2e-54 traF CO Thioredoxin
MIHOOLGA_03871 2.4e-56 yusD S SCP-2 sterol transfer family
MIHOOLGA_03872 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIHOOLGA_03873 3e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MIHOOLGA_03874 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
MIHOOLGA_03875 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIHOOLGA_03876 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MIHOOLGA_03877 1.4e-245 sufD O assembly protein SufD
MIHOOLGA_03878 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIHOOLGA_03879 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MIHOOLGA_03880 3.5e-271 sufB O FeS cluster assembly
MIHOOLGA_03881 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIHOOLGA_03882 1e-41
MIHOOLGA_03884 3.3e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MIHOOLGA_03885 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MIHOOLGA_03886 4.4e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MIHOOLGA_03887 1.6e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MIHOOLGA_03888 4.5e-155 yurN G Binding-protein-dependent transport system inner membrane component
MIHOOLGA_03889 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
MIHOOLGA_03890 5.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MIHOOLGA_03891 9.5e-135 yurK K UTRA
MIHOOLGA_03892 1e-204 msmX P Belongs to the ABC transporter superfamily
MIHOOLGA_03893 2.4e-169 bsn L Ribonuclease
MIHOOLGA_03894 6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIHOOLGA_03895 1.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MIHOOLGA_03897 4.4e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MIHOOLGA_03898 3.8e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MIHOOLGA_03899 8.6e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MIHOOLGA_03900 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MIHOOLGA_03901 2.9e-93 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MIHOOLGA_03903 1.1e-190 S Aspartate phosphatase response regulator
MIHOOLGA_03906 6.7e-14 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MIHOOLGA_03907 6.3e-104 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MIHOOLGA_03908 2.5e-48 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MIHOOLGA_03909 8.9e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MIHOOLGA_03910 1.8e-221 pbuX F xanthine
MIHOOLGA_03911 1.1e-234 pbuX F Permease family
MIHOOLGA_03912 2.2e-301 pucR QT COG2508 Regulator of polyketide synthase expression
MIHOOLGA_03913 2.1e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MIHOOLGA_03914 3e-62 yunG
MIHOOLGA_03915 1.8e-169 yunF S Protein of unknown function DUF72
MIHOOLGA_03916 5.9e-141 yunE S membrane transporter protein
MIHOOLGA_03917 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MIHOOLGA_03918 1.1e-47 yunC S Domain of unknown function (DUF1805)
MIHOOLGA_03919 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
MIHOOLGA_03920 1.3e-195 lytH M Peptidase, M23
MIHOOLGA_03921 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIHOOLGA_03922 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIHOOLGA_03923 9.7e-48 yutD S protein conserved in bacteria
MIHOOLGA_03924 1e-75 yutE S Protein of unknown function DUF86
MIHOOLGA_03925 7.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MIHOOLGA_03926 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MIHOOLGA_03927 5.9e-199 yutH S Spore coat protein
MIHOOLGA_03928 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
MIHOOLGA_03929 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIHOOLGA_03930 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIHOOLGA_03931 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MIHOOLGA_03932 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MIHOOLGA_03933 3e-56 yuzD S protein conserved in bacteria
MIHOOLGA_03934 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MIHOOLGA_03935 3.2e-39 yuzB S Belongs to the UPF0349 family
MIHOOLGA_03936 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIHOOLGA_03937 8.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIHOOLGA_03938 3.7e-63 erpA S Belongs to the HesB IscA family
MIHOOLGA_03939 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIHOOLGA_03940 2.5e-115 paiB K Putative FMN-binding domain
MIHOOLGA_03941 2.5e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MIHOOLGA_03943 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
MIHOOLGA_03944 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
MIHOOLGA_03945 8.4e-27 yuiB S Putative membrane protein
MIHOOLGA_03946 1.8e-116 yuiC S protein conserved in bacteria
MIHOOLGA_03947 1.2e-77 yuiD S protein conserved in bacteria
MIHOOLGA_03948 7.6e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIHOOLGA_03949 3.9e-211 yuiF S antiporter
MIHOOLGA_03950 4.4e-93 bioY S Biotin biosynthesis protein
MIHOOLGA_03951 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
MIHOOLGA_03952 1.5e-166 besA S Putative esterase
MIHOOLGA_03953 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIHOOLGA_03954 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
MIHOOLGA_03955 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MIHOOLGA_03956 2e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MIHOOLGA_03957 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MIHOOLGA_03958 3.8e-36 mbtH S MbtH-like protein
MIHOOLGA_03959 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MIHOOLGA_03960 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MIHOOLGA_03961 1.5e-228 yukF QT Transcriptional regulator
MIHOOLGA_03962 2.8e-45 esxA S Belongs to the WXG100 family
MIHOOLGA_03963 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MIHOOLGA_03964 2.6e-210 essB S WXG100 protein secretion system (Wss), protein YukC
MIHOOLGA_03965 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MIHOOLGA_03966 0.0 esaA S type VII secretion protein EsaA
MIHOOLGA_03967 5.6e-64 yueC S Family of unknown function (DUF5383)
MIHOOLGA_03968 6.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIHOOLGA_03969 1.4e-95 yueE S phosphohydrolase
MIHOOLGA_03970 2.9e-24 S Protein of unknown function (DUF2642)
MIHOOLGA_03971 6.5e-66 S Protein of unknown function (DUF2283)
MIHOOLGA_03972 3.2e-190 yueF S transporter activity
MIHOOLGA_03973 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MIHOOLGA_03974 2.8e-38 yueH S YueH-like protein
MIHOOLGA_03975 5.1e-66 yueI S Protein of unknown function (DUF1694)
MIHOOLGA_03976 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
MIHOOLGA_03977 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIHOOLGA_03978 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MIHOOLGA_03979 1.1e-22 yuzC
MIHOOLGA_03981 1.7e-128 comQ H Belongs to the FPP GGPP synthase family
MIHOOLGA_03983 0.0 comP 2.7.13.3 T Histidine kinase
MIHOOLGA_03984 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIHOOLGA_03985 6.7e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MIHOOLGA_03986 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MIHOOLGA_03987 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIHOOLGA_03988 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIHOOLGA_03989 4.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIHOOLGA_03990 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIHOOLGA_03991 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIHOOLGA_03992 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIHOOLGA_03993 2.1e-13
MIHOOLGA_03994 1.3e-233 maeN C COG3493 Na citrate symporter
MIHOOLGA_03995 1.9e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
MIHOOLGA_03996 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MIHOOLGA_03997 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MIHOOLGA_03998 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MIHOOLGA_03999 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MIHOOLGA_04000 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIHOOLGA_04001 6.3e-78 yufK S Family of unknown function (DUF5366)
MIHOOLGA_04002 6.3e-75 yuxK S protein conserved in bacteria
MIHOOLGA_04003 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MIHOOLGA_04004 1.2e-183 yuxJ EGP Major facilitator Superfamily
MIHOOLGA_04006 1.9e-115 kapD L the KinA pathway to sporulation
MIHOOLGA_04007 4.1e-68 kapB G Kinase associated protein B
MIHOOLGA_04008 4.6e-233 T PhoQ Sensor
MIHOOLGA_04009 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MIHOOLGA_04010 4.6e-39 yugE S Domain of unknown function (DUF1871)
MIHOOLGA_04011 6.5e-156 yugF I Hydrolase
MIHOOLGA_04012 1.6e-85 alaR K Transcriptional regulator
MIHOOLGA_04013 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MIHOOLGA_04014 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MIHOOLGA_04015 1.1e-34 yuzA S Domain of unknown function (DUF378)
MIHOOLGA_04016 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MIHOOLGA_04017 1.1e-228 yugK C Dehydrogenase
MIHOOLGA_04018 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MIHOOLGA_04020 1.3e-72 yugN S YugN-like family
MIHOOLGA_04021 5.3e-181 yugO P COG1226 Kef-type K transport systems
MIHOOLGA_04022 5.4e-53 mstX S Membrane-integrating protein Mistic
MIHOOLGA_04023 2.3e-38
MIHOOLGA_04024 1.4e-116 yugP S Zn-dependent protease
MIHOOLGA_04025 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MIHOOLGA_04026 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MIHOOLGA_04027 2.1e-72 yugU S Uncharacterised protein family UPF0047
MIHOOLGA_04028 1e-35
MIHOOLGA_04029 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MIHOOLGA_04030 9.9e-75 mcpA NT chemotaxis protein
MIHOOLGA_04031 8.2e-122 mcpA NT chemotaxis protein
MIHOOLGA_04032 2.1e-221 mcpA NT chemotaxis protein
MIHOOLGA_04033 8.5e-295 mcpA NT chemotaxis protein
MIHOOLGA_04034 2.5e-238 mcpA NT chemotaxis protein
MIHOOLGA_04035 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MIHOOLGA_04036 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MIHOOLGA_04037 1.1e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MIHOOLGA_04038 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MIHOOLGA_04039 4.8e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MIHOOLGA_04040 3.3e-183 ygjR S Oxidoreductase
MIHOOLGA_04041 4.8e-189 yubA S transporter activity
MIHOOLGA_04042 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIHOOLGA_04044 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MIHOOLGA_04045 2.4e-273 yubD P Major Facilitator Superfamily
MIHOOLGA_04046 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MIHOOLGA_04047 1e-38 yiaA S yiaA/B two helix domain
MIHOOLGA_04048 1.9e-234 ktrB P Potassium
MIHOOLGA_04049 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MIHOOLGA_04050 2.2e-91 yuaB
MIHOOLGA_04051 3.6e-94 yuaC K Belongs to the GbsR family
MIHOOLGA_04052 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MIHOOLGA_04053 1.4e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
MIHOOLGA_04054 5.6e-106 yuaD
MIHOOLGA_04055 8.7e-84 yuaE S DinB superfamily
MIHOOLGA_04056 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MIHOOLGA_04057 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
MIHOOLGA_04058 4.9e-93 M1-753 M FR47-like protein
MIHOOLGA_04059 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MIHOOLGA_04060 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MIHOOLGA_04061 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIHOOLGA_04062 2.6e-29 yazB K transcriptional
MIHOOLGA_04063 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIHOOLGA_04064 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIHOOLGA_04065 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIHOOLGA_04066 1.8e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MIHOOLGA_04067 5.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MIHOOLGA_04068 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIHOOLGA_04069 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIHOOLGA_04070 4e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MIHOOLGA_04071 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIHOOLGA_04072 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIHOOLGA_04073 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIHOOLGA_04074 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MIHOOLGA_04075 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIHOOLGA_04076 6.3e-185 KLT serine threonine protein kinase
MIHOOLGA_04077 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MIHOOLGA_04078 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MIHOOLGA_04081 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MIHOOLGA_04082 1.1e-44 divIC D Septum formation initiator
MIHOOLGA_04083 2.1e-106 yabQ S spore cortex biosynthesis protein
MIHOOLGA_04084 1.5e-49 yabP S Sporulation protein YabP
MIHOOLGA_04085 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MIHOOLGA_04086 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MIHOOLGA_04087 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIHOOLGA_04088 1.5e-92 spoVT K stage V sporulation protein
MIHOOLGA_04089 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIHOOLGA_04090 2.4e-39 yabK S Peptide ABC transporter permease
MIHOOLGA_04091 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIHOOLGA_04092 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIHOOLGA_04093 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIHOOLGA_04094 9.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIHOOLGA_04095 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MIHOOLGA_04096 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MIHOOLGA_04097 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MIHOOLGA_04098 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIHOOLGA_04099 8.3e-27 sspF S DNA topological change
MIHOOLGA_04100 7.8e-39 veg S protein conserved in bacteria
MIHOOLGA_04101 1.8e-135 yabG S peptidase
MIHOOLGA_04102 3.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIHOOLGA_04103 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MIHOOLGA_04104 2e-167 rpfB GH23 T protein conserved in bacteria
MIHOOLGA_04105 3.4e-143 tatD L hydrolase, TatD
MIHOOLGA_04106 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIHOOLGA_04107 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MIHOOLGA_04108 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIHOOLGA_04109 2.5e-49 yazA L endonuclease containing a URI domain
MIHOOLGA_04110 7.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MIHOOLGA_04111 4.8e-31 yabA L Involved in initiation control of chromosome replication
MIHOOLGA_04112 6.1e-146 yaaT S stage 0 sporulation protein
MIHOOLGA_04113 1e-176 holB 2.7.7.7 L DNA polymerase III
MIHOOLGA_04114 1.5e-71 yaaR S protein conserved in bacteria
MIHOOLGA_04115 2.2e-54 yaaQ S protein conserved in bacteria
MIHOOLGA_04116 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIHOOLGA_04117 1.1e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MIHOOLGA_04118 8.4e-202 yaaN P Belongs to the TelA family
MIHOOLGA_04119 7.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MIHOOLGA_04120 3.4e-31 csfB S Inhibitor of sigma-G Gin

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)