ORF_ID e_value Gene_name EC_number CAZy COGs Description
CMMIKGOF_00001 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CMMIKGOF_00002 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00003 2.5e-43 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CMMIKGOF_00004 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CMMIKGOF_00005 7.8e-171 murB 1.3.1.98 M cell wall formation
CMMIKGOF_00006 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMMIKGOF_00007 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
CMMIKGOF_00008 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
CMMIKGOF_00009 2.3e-206 potD P spermidine putrescine ABC transporter
CMMIKGOF_00010 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
CMMIKGOF_00011 9.6e-26 XK27_08050 O HflC and HflK could regulate a protease
CMMIKGOF_00012 7.2e-61 XK27_08050 O stress-induced mitochondrial fusion
CMMIKGOF_00013 4e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
CMMIKGOF_00014 2.7e-97 GK ROK family
CMMIKGOF_00015 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CMMIKGOF_00016 1.9e-103 wecD M Acetyltransferase GNAT family
CMMIKGOF_00017 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMMIKGOF_00018 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
CMMIKGOF_00019 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
CMMIKGOF_00021 1.1e-54 lrgA S Effector of murein hydrolase LrgA
CMMIKGOF_00022 2.2e-117 lrgB M effector of murein hydrolase
CMMIKGOF_00023 2.6e-109 3.1.3.18 S IA, variant 1
CMMIKGOF_00024 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMMIKGOF_00025 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMMIKGOF_00026 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
CMMIKGOF_00027 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CMMIKGOF_00028 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00029 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00030 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
CMMIKGOF_00032 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
CMMIKGOF_00034 4e-50 ycaO O OsmC-like protein
CMMIKGOF_00035 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
CMMIKGOF_00038 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMMIKGOF_00040 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMMIKGOF_00041 2.4e-16 XK27_00735
CMMIKGOF_00042 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_00043 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CMMIKGOF_00044 4e-33 S CAAX amino terminal protease family protein
CMMIKGOF_00045 4.3e-82 S CAAX amino terminal protease family protein
CMMIKGOF_00047 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMMIKGOF_00048 2.2e-84 mutT 3.6.1.55 F Nudix family
CMMIKGOF_00049 5.3e-142 ET Belongs to the bacterial solute-binding protein 3 family
CMMIKGOF_00050 9.4e-136 ET ABC transporter
CMMIKGOF_00051 5.8e-200 arcT 2.6.1.1 E Aminotransferase
CMMIKGOF_00052 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
CMMIKGOF_00053 7.8e-26 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CMMIKGOF_00054 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMMIKGOF_00055 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMMIKGOF_00056 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CMMIKGOF_00057 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CMMIKGOF_00058 1.6e-244
CMMIKGOF_00059 5.8e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMMIKGOF_00060 2.3e-159 L Helix-turn-helix domain of transposase family ISL3
CMMIKGOF_00061 4.8e-09 L Transposase
CMMIKGOF_00062 4.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
CMMIKGOF_00063 2.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
CMMIKGOF_00064 1.4e-142 rgpC GM Transport permease protein
CMMIKGOF_00065 1.3e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CMMIKGOF_00066 1.8e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMMIKGOF_00067 0.0 rgpF M Rhamnan synthesis protein F
CMMIKGOF_00068 1.1e-98
CMMIKGOF_00069 1.1e-181
CMMIKGOF_00070 2.6e-118 radC E Belongs to the UPF0758 family
CMMIKGOF_00071 1.6e-131 puuD T peptidase C26
CMMIKGOF_00072 3.6e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMMIKGOF_00073 1.2e-249 L Transposase
CMMIKGOF_00074 2e-58 XK27_04120 S Putative amino acid metabolism
CMMIKGOF_00075 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
CMMIKGOF_00076 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMMIKGOF_00077 1.5e-103 yjbK S Adenylate cyclase
CMMIKGOF_00078 4.6e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CMMIKGOF_00079 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMMIKGOF_00080 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CMMIKGOF_00081 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CMMIKGOF_00082 8.9e-18 L transposase activity
CMMIKGOF_00083 1.1e-23 L transposase activity
CMMIKGOF_00084 2.1e-85 L Integrase core domain protein
CMMIKGOF_00085 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
CMMIKGOF_00086 8.9e-40 tatD L Hydrolase, tatd
CMMIKGOF_00087 3.5e-24 oppF P Belongs to the ABC transporter superfamily
CMMIKGOF_00088 1.2e-24 oppF P Belongs to the ABC transporter superfamily
CMMIKGOF_00089 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CMMIKGOF_00090 3e-229 L Transposase
CMMIKGOF_00091 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CMMIKGOF_00092 4.2e-278 amiC P ABC transporter (Permease
CMMIKGOF_00093 6.3e-168 amiD P ABC transporter (Permease
CMMIKGOF_00094 2.2e-204 oppD P Belongs to the ABC transporter superfamily
CMMIKGOF_00095 4.3e-172 oppF P Belongs to the ABC transporter superfamily
CMMIKGOF_00096 5.6e-133 V ATPase activity
CMMIKGOF_00097 6.3e-120 skfE V abc transporter atp-binding protein
CMMIKGOF_00098 8.6e-63 yvoA_1 K Transcriptional
CMMIKGOF_00099 7.6e-146 supH S overlaps another CDS with the same product name
CMMIKGOF_00100 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
CMMIKGOF_00101 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMMIKGOF_00102 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CMMIKGOF_00103 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CMMIKGOF_00104 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMMIKGOF_00105 5.6e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMMIKGOF_00106 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMMIKGOF_00107 2e-132 stp 3.1.3.16 T phosphatase
CMMIKGOF_00108 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CMMIKGOF_00109 3.7e-120 yvqF KT membrane
CMMIKGOF_00110 5.8e-175 vraS 2.7.13.3 T Histidine kinase
CMMIKGOF_00111 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMMIKGOF_00114 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMMIKGOF_00115 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CMMIKGOF_00116 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CMMIKGOF_00117 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CMMIKGOF_00118 2.3e-87 L Transposase
CMMIKGOF_00119 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CMMIKGOF_00120 4.3e-40 V abc transporter atp-binding protein
CMMIKGOF_00121 2.5e-101 V abc transporter atp-binding protein
CMMIKGOF_00122 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CMMIKGOF_00123 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CMMIKGOF_00124 1.2e-25 L transposition
CMMIKGOF_00125 2.7e-08 L Integrase core domain protein
CMMIKGOF_00126 3e-184 galR K Transcriptional regulator
CMMIKGOF_00127 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMMIKGOF_00128 7.8e-285 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CMMIKGOF_00129 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMMIKGOF_00130 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CMMIKGOF_00131 0.0 lacS G transporter
CMMIKGOF_00132 0.0 lacL 3.2.1.23 G -beta-galactosidase
CMMIKGOF_00133 2.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CMMIKGOF_00134 0.0 sbcC L ATPase involved in DNA repair
CMMIKGOF_00135 2.8e-85
CMMIKGOF_00137 1.8e-87 L transposase activity
CMMIKGOF_00138 1.4e-150 L Integrase core domain protein
CMMIKGOF_00139 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_00140 2.1e-257 I radical SAM domain protein
CMMIKGOF_00141 1.2e-176 EGP Major Facilitator Superfamily
CMMIKGOF_00142 1.5e-109 C Fe-S oxidoreductases
CMMIKGOF_00144 1.1e-151 V MatE
CMMIKGOF_00145 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
CMMIKGOF_00146 2e-162 hrtB V MacB-like periplasmic core domain
CMMIKGOF_00148 0.0 M family 8
CMMIKGOF_00149 2.7e-09
CMMIKGOF_00150 5.6e-08
CMMIKGOF_00151 5.8e-109 MA20_06410 E LysE type translocator
CMMIKGOF_00152 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
CMMIKGOF_00153 1.5e-24 IQ PFAM AMP-dependent synthetase and ligase
CMMIKGOF_00154 4e-20
CMMIKGOF_00155 1.9e-35
CMMIKGOF_00156 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMMIKGOF_00157 1.6e-58
CMMIKGOF_00159 4.3e-31 S Signal peptide protein, YSIRK family
CMMIKGOF_00160 1.4e-54 K response regulator
CMMIKGOF_00161 1.1e-37 BP1961 P nitric oxide dioxygenase activity
CMMIKGOF_00163 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
CMMIKGOF_00164 2.7e-182 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMMIKGOF_00165 6.8e-161 yvgN C reductase
CMMIKGOF_00167 5e-66 yoaK S Protein of unknown function (DUF1275)
CMMIKGOF_00168 1.4e-110 drgA C Nitroreductase
CMMIKGOF_00169 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMMIKGOF_00170 2.8e-157 E Alpha/beta hydrolase of unknown function (DUF915)
CMMIKGOF_00171 5.6e-77 ywnA K Transcriptional regulator
CMMIKGOF_00172 9.5e-150 1.13.11.2 S glyoxalase
CMMIKGOF_00173 1.5e-109 XK27_02070 S nitroreductase
CMMIKGOF_00174 6.2e-228 yfnA E amino acid
CMMIKGOF_00175 9.6e-26 csbD K CsbD-like
CMMIKGOF_00176 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMMIKGOF_00177 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMMIKGOF_00178 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
CMMIKGOF_00179 6e-168 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMMIKGOF_00180 1.5e-247 norM V Multidrug efflux pump
CMMIKGOF_00181 9.2e-119 pbuX F xanthine permease
CMMIKGOF_00182 3.3e-69 pbuX F xanthine permease
CMMIKGOF_00183 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMMIKGOF_00184 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMMIKGOF_00185 6.2e-166 T Histidine kinase
CMMIKGOF_00186 1.9e-133 macB2 V ABC transporter, ATP-binding protein
CMMIKGOF_00187 0.0 V ABC transporter (permease)
CMMIKGOF_00188 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
CMMIKGOF_00189 1.5e-30 liaI KT membrane
CMMIKGOF_00190 1.4e-15 liaI KT membrane
CMMIKGOF_00191 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
CMMIKGOF_00192 3.7e-122 S An automated process has identified a potential problem with this gene model
CMMIKGOF_00194 4.6e-42 3.6.1.55 F NUDIX domain
CMMIKGOF_00195 2.3e-151 mutR K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_00196 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
CMMIKGOF_00197 3.3e-212 EGP Major facilitator Superfamily
CMMIKGOF_00201 9.7e-158 XK27_09825 V abc transporter atp-binding protein
CMMIKGOF_00202 1.5e-132 yvfS V ABC-2 type transporter
CMMIKGOF_00203 5.3e-37 desK 2.7.13.3 T Histidine kinase
CMMIKGOF_00204 7.8e-141 desK 2.7.13.3 T Histidine kinase
CMMIKGOF_00205 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMMIKGOF_00206 3.6e-97 S transport system, permease component
CMMIKGOF_00207 1.1e-144 S ABC-2 family transporter protein
CMMIKGOF_00208 7.4e-26
CMMIKGOF_00209 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
CMMIKGOF_00210 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
CMMIKGOF_00211 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CMMIKGOF_00212 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMMIKGOF_00213 6.9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMMIKGOF_00214 3e-13
CMMIKGOF_00215 2.8e-93 pat 2.3.1.183 M acetyltransferase
CMMIKGOF_00216 7.3e-82 alkD L Dna alkylation repair
CMMIKGOF_00217 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMMIKGOF_00218 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMMIKGOF_00219 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMMIKGOF_00220 0.0 smc D Required for chromosome condensation and partitioning
CMMIKGOF_00221 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMMIKGOF_00222 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMMIKGOF_00223 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMMIKGOF_00225 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CMMIKGOF_00226 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMMIKGOF_00228 2e-86 S ECF-type riboflavin transporter, S component
CMMIKGOF_00229 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CMMIKGOF_00230 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CMMIKGOF_00231 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
CMMIKGOF_00232 1.9e-294 yfmM S abc transporter atp-binding protein
CMMIKGOF_00233 2.8e-257 noxE P NADH oxidase
CMMIKGOF_00234 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMMIKGOF_00235 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMMIKGOF_00236 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CMMIKGOF_00237 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
CMMIKGOF_00238 1.8e-165 ypuA S secreted protein
CMMIKGOF_00239 3.3e-26 L Transposase (IS116 IS110 IS902 family)
CMMIKGOF_00240 4.2e-71 L Transposase (IS116 IS110 IS902 family)
CMMIKGOF_00242 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMMIKGOF_00243 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMMIKGOF_00244 2.2e-34 nrdH O Glutaredoxin
CMMIKGOF_00245 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CMMIKGOF_00246 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
CMMIKGOF_00247 2.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
CMMIKGOF_00248 7.9e-39 ptsH G phosphocarrier protein Hpr
CMMIKGOF_00249 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMMIKGOF_00250 5.6e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CMMIKGOF_00251 6.2e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMMIKGOF_00252 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
CMMIKGOF_00253 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CMMIKGOF_00254 0.0 uup S abc transporter atp-binding protein
CMMIKGOF_00255 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
CMMIKGOF_00256 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMMIKGOF_00257 8.7e-150 cobQ S glutamine amidotransferase
CMMIKGOF_00258 1.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CMMIKGOF_00259 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMMIKGOF_00260 6e-169 ybbR S Protein conserved in bacteria
CMMIKGOF_00261 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMMIKGOF_00262 1.7e-70 gtrA S GtrA-like protein
CMMIKGOF_00263 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CMMIKGOF_00264 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMMIKGOF_00265 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
CMMIKGOF_00266 1.1e-206 yurR 1.4.5.1 E oxidoreductase
CMMIKGOF_00267 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMMIKGOF_00268 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CMMIKGOF_00269 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMMIKGOF_00272 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
CMMIKGOF_00273 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
CMMIKGOF_00274 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMMIKGOF_00275 1.1e-121 ylfI S tigr01906
CMMIKGOF_00276 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CMMIKGOF_00277 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CMMIKGOF_00278 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CMMIKGOF_00279 1.3e-22 XK27_08085
CMMIKGOF_00280 5.2e-36 L transposase activity
CMMIKGOF_00281 1.8e-21 L Transposase
CMMIKGOF_00282 5.3e-56 L transposition
CMMIKGOF_00283 1.9e-86 L Integrase core domain protein
CMMIKGOF_00284 8.2e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMMIKGOF_00285 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMMIKGOF_00286 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CMMIKGOF_00287 3.5e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMMIKGOF_00288 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CMMIKGOF_00289 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMMIKGOF_00290 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMMIKGOF_00291 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CMMIKGOF_00292 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMMIKGOF_00293 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
CMMIKGOF_00294 5.6e-240 rodA D Belongs to the SEDS family
CMMIKGOF_00295 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMMIKGOF_00296 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CMMIKGOF_00297 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMMIKGOF_00298 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CMMIKGOF_00299 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CMMIKGOF_00300 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMMIKGOF_00301 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMMIKGOF_00302 2.9e-125 dnaD
CMMIKGOF_00303 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMMIKGOF_00306 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMMIKGOF_00307 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
CMMIKGOF_00308 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMMIKGOF_00309 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CMMIKGOF_00310 3.7e-73 argR K Regulates arginine biosynthesis genes
CMMIKGOF_00311 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
CMMIKGOF_00312 1e-148 DegV S DegV family
CMMIKGOF_00313 6e-144 ypmR E lipolytic protein G-D-S-L family
CMMIKGOF_00314 2.1e-84 ypmS S Protein conserved in bacteria
CMMIKGOF_00315 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMMIKGOF_00317 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CMMIKGOF_00318 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMMIKGOF_00319 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMMIKGOF_00320 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CMMIKGOF_00321 2.5e-43 ysdA L Membrane
CMMIKGOF_00322 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMMIKGOF_00323 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMMIKGOF_00324 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
CMMIKGOF_00325 0.0 dnaE 2.7.7.7 L DNA polymerase
CMMIKGOF_00326 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMMIKGOF_00327 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CMMIKGOF_00328 1.6e-249 L Transposase
CMMIKGOF_00330 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
CMMIKGOF_00331 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
CMMIKGOF_00332 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
CMMIKGOF_00334 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
CMMIKGOF_00335 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CMMIKGOF_00336 1.2e-135 XK27_08845 S abc transporter atp-binding protein
CMMIKGOF_00337 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMMIKGOF_00338 3.5e-151 estA CE1 S Putative esterase
CMMIKGOF_00339 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
CMMIKGOF_00341 2.3e-75 fld C Flavodoxin
CMMIKGOF_00342 1.3e-282 clcA P Chloride transporter, ClC family
CMMIKGOF_00343 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CMMIKGOF_00344 2.1e-219 XK27_05110 P chloride
CMMIKGOF_00345 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMMIKGOF_00347 5.8e-80
CMMIKGOF_00348 1.9e-20 WQ51_02665 S Protein of unknown function (DUF3042)
CMMIKGOF_00349 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMMIKGOF_00350 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CMMIKGOF_00351 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMMIKGOF_00352 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMMIKGOF_00353 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMMIKGOF_00354 8.3e-28 G Domain of unknown function (DUF4832)
CMMIKGOF_00355 5.6e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMMIKGOF_00357 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMMIKGOF_00358 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
CMMIKGOF_00359 2.4e-124 endA F DNA RNA non-specific endonuclease
CMMIKGOF_00360 4.2e-110 tcyB_2 P ABC transporter (permease)
CMMIKGOF_00361 8e-115 gltJ P ABC transporter (Permease
CMMIKGOF_00362 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CMMIKGOF_00363 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_00364 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMMIKGOF_00365 1.5e-247 vicK 2.7.13.3 T Histidine kinase
CMMIKGOF_00366 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CMMIKGOF_00367 5e-35 F Protein of unknown function (DUF454)
CMMIKGOF_00368 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CMMIKGOF_00369 9.2e-147 yidA S hydrolases of the HAD superfamily
CMMIKGOF_00370 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
CMMIKGOF_00371 2.6e-67 ywiB S Domain of unknown function (DUF1934)
CMMIKGOF_00372 0.0 pacL 3.6.3.8 P cation transport ATPase
CMMIKGOF_00373 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CMMIKGOF_00374 1.1e-180 yjjH S Calcineurin-like phosphoesterase
CMMIKGOF_00375 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CMMIKGOF_00376 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMMIKGOF_00377 2.5e-124 ftsE D cell division ATP-binding protein FtsE
CMMIKGOF_00378 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CMMIKGOF_00379 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CMMIKGOF_00380 6.2e-176 yubA S permease
CMMIKGOF_00381 3.7e-224 G COG0457 FOG TPR repeat
CMMIKGOF_00382 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMMIKGOF_00383 4.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMMIKGOF_00384 2.9e-90 ebsA S Family of unknown function (DUF5322)
CMMIKGOF_00385 2.8e-18 M LysM domain
CMMIKGOF_00386 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CMMIKGOF_00387 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMMIKGOF_00388 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CMMIKGOF_00389 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMMIKGOF_00390 4.7e-24 L Transposase
CMMIKGOF_00391 2.6e-85 XK27_03610 K Gnat family
CMMIKGOF_00392 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CMMIKGOF_00393 1.1e-275 pepV 3.5.1.18 E Dipeptidase
CMMIKGOF_00394 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMMIKGOF_00395 4e-21 V Glucan-binding protein C
CMMIKGOF_00397 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMMIKGOF_00398 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CMMIKGOF_00399 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CMMIKGOF_00400 9.4e-66 clcA_2 P chloride
CMMIKGOF_00401 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
CMMIKGOF_00402 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
CMMIKGOF_00403 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CMMIKGOF_00404 2.2e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CMMIKGOF_00405 2.3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CMMIKGOF_00406 1.9e-108 cps4C M biosynthesis protein
CMMIKGOF_00407 2.2e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
CMMIKGOF_00408 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CMMIKGOF_00409 1.3e-218 rgpAc GT4 M group 1 family protein
CMMIKGOF_00410 1.2e-208 wcoF M Glycosyltransferase, group 1 family protein
CMMIKGOF_00411 3.7e-221 L Transposase
CMMIKGOF_00412 5.1e-105 Z012_10770 M Domain of unknown function (DUF1919)
CMMIKGOF_00414 1.1e-122 M Glycosyltransferase, group 2 family protein
CMMIKGOF_00415 6e-148 M Glycosyltransferase like family 2
CMMIKGOF_00416 6.3e-173
CMMIKGOF_00417 8.3e-244 epsU S Polysaccharide biosynthesis protein
CMMIKGOF_00418 6.9e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
CMMIKGOF_00419 1.4e-192 wbbI M transferase activity, transferring glycosyl groups
CMMIKGOF_00420 5.4e-161 L Transposase
CMMIKGOF_00421 2.7e-51 L Transposase
CMMIKGOF_00422 2.2e-94 V VanZ like family
CMMIKGOF_00423 6.8e-88 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CMMIKGOF_00424 3.1e-87 G Belongs to the phosphoglycerate mutase family
CMMIKGOF_00425 1.3e-199 S hmm pf01594
CMMIKGOF_00426 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMMIKGOF_00427 2.1e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMMIKGOF_00428 1.1e-38 S granule-associated protein
CMMIKGOF_00429 3.5e-291 S unusual protein kinase
CMMIKGOF_00430 3.4e-29 estA E Lysophospholipase L1 and related esterases
CMMIKGOF_00431 1.4e-69 estA E GDSL-like protein
CMMIKGOF_00432 1.2e-157 rssA S Phospholipase, patatin family
CMMIKGOF_00433 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_00434 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_00435 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_00436 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_00437 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMMIKGOF_00438 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMMIKGOF_00439 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMMIKGOF_00440 0.0 S the current gene model (or a revised gene model) may contain a frame shift
CMMIKGOF_00441 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
CMMIKGOF_00442 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
CMMIKGOF_00443 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CMMIKGOF_00444 2.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CMMIKGOF_00445 5.4e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMMIKGOF_00446 0.0 lpdA 1.8.1.4 C Dehydrogenase
CMMIKGOF_00447 9.9e-12 3.5.1.28 NU amidase activity
CMMIKGOF_00448 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CMMIKGOF_00449 8.5e-266 3.5.1.28 NU amidase activity
CMMIKGOF_00450 1.9e-37 3.5.1.28 NU amidase activity
CMMIKGOF_00451 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00452 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00453 5e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00454 3.1e-63 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00455 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMMIKGOF_00456 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
CMMIKGOF_00457 3.3e-233 ycdB P peroxidase
CMMIKGOF_00458 1.8e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CMMIKGOF_00459 7.6e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMMIKGOF_00460 4.6e-25 tatA U protein secretion
CMMIKGOF_00461 2.3e-23 L Transposase
CMMIKGOF_00462 1.3e-48 malR K Transcriptional regulator
CMMIKGOF_00463 9.9e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CMMIKGOF_00464 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMMIKGOF_00465 3.7e-09
CMMIKGOF_00466 1.1e-17
CMMIKGOF_00467 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
CMMIKGOF_00468 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CMMIKGOF_00469 0.0 pepN 3.4.11.2 E aminopeptidase
CMMIKGOF_00470 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
CMMIKGOF_00471 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMMIKGOF_00472 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMMIKGOF_00473 1.2e-155 pstA P phosphate transport system permease
CMMIKGOF_00474 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CMMIKGOF_00475 3.3e-158 pstS P phosphate
CMMIKGOF_00476 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CMMIKGOF_00477 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CMMIKGOF_00478 1.9e-43 yktA S Belongs to the UPF0223 family
CMMIKGOF_00479 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMMIKGOF_00480 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CMMIKGOF_00481 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMMIKGOF_00482 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
CMMIKGOF_00483 1.4e-95 XK27_04775 S hemerythrin HHE cation binding domain
CMMIKGOF_00484 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
CMMIKGOF_00485 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CMMIKGOF_00486 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMMIKGOF_00487 7.8e-61 S haloacid dehalogenase-like hydrolase
CMMIKGOF_00488 1.8e-31 S haloacid dehalogenase-like hydrolase
CMMIKGOF_00489 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
CMMIKGOF_00490 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CMMIKGOF_00491 3.1e-240 agcS E (Alanine) symporter
CMMIKGOF_00492 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMMIKGOF_00493 8.4e-72 yfiF3 K sequence-specific DNA binding
CMMIKGOF_00494 2.6e-23 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CMMIKGOF_00496 5.5e-53 yecS P ABC transporter (Permease
CMMIKGOF_00497 2.9e-58 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
CMMIKGOF_00498 2.4e-61 yckB ET Belongs to the bacterial solute-binding protein 3 family
CMMIKGOF_00499 1.2e-103 nylA 3.5.1.4 J Belongs to the amidase family
CMMIKGOF_00500 6.7e-265 dtpT U POT family
CMMIKGOF_00501 2.2e-16 nylA 3.5.1.4 J amidase activity
CMMIKGOF_00502 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMMIKGOF_00503 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMMIKGOF_00504 4.4e-61 csm6 S Psort location Cytoplasmic, score
CMMIKGOF_00506 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
CMMIKGOF_00507 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
CMMIKGOF_00508 1.6e-117 csm3 L RAMP superfamily
CMMIKGOF_00509 2.5e-62 csm2 L Csm2 Type III-A
CMMIKGOF_00510 0.0 csm1 S CRISPR-associated protein Csm1 family
CMMIKGOF_00511 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
CMMIKGOF_00512 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00513 1.5e-42 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00514 7.8e-107 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00515 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMMIKGOF_00516 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CMMIKGOF_00517 1.5e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CMMIKGOF_00518 4.3e-118 S TraX protein
CMMIKGOF_00520 3.5e-28 3.4.13.21 I Protein conserved in bacteria
CMMIKGOF_00521 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
CMMIKGOF_00522 3.7e-190
CMMIKGOF_00523 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CMMIKGOF_00525 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
CMMIKGOF_00526 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
CMMIKGOF_00527 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
CMMIKGOF_00528 2.6e-143 2.4.2.3 F Phosphorylase superfamily
CMMIKGOF_00531 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
CMMIKGOF_00532 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
CMMIKGOF_00533 6e-08 S Hydrolases of the alpha beta superfamily
CMMIKGOF_00534 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
CMMIKGOF_00535 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CMMIKGOF_00536 1.8e-159 czcD P cation diffusion facilitator family transporter
CMMIKGOF_00537 9e-98 K Transcriptional regulator, TetR family
CMMIKGOF_00538 1.6e-10
CMMIKGOF_00539 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMMIKGOF_00540 6.4e-104 V ABC transporter (Permease
CMMIKGOF_00541 4.8e-28 L Helix-turn-helix domain of transposase family ISL3
CMMIKGOF_00542 6.3e-111 L Transposase
CMMIKGOF_00543 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CMMIKGOF_00544 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CMMIKGOF_00545 6.6e-61 EGP Major facilitator Superfamily
CMMIKGOF_00546 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
CMMIKGOF_00547 1.3e-212 pqqE C radical SAM domain protein
CMMIKGOF_00550 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_00551 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMMIKGOF_00552 3.9e-19 IQ Acetoin reductase
CMMIKGOF_00553 1.8e-51 IQ Acetoin reductase
CMMIKGOF_00554 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMMIKGOF_00555 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CMMIKGOF_00556 7.1e-152 XK27_05470 E Methionine synthase
CMMIKGOF_00557 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMMIKGOF_00558 1.3e-249 T PhoQ Sensor
CMMIKGOF_00559 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMMIKGOF_00560 3.6e-154 S TraX protein
CMMIKGOF_00561 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMMIKGOF_00562 8.3e-159 dprA LU DNA protecting protein DprA
CMMIKGOF_00563 4.1e-167 GK ROK family
CMMIKGOF_00564 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMMIKGOF_00565 2.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMMIKGOF_00566 4.8e-128 K DNA-binding helix-turn-helix protein
CMMIKGOF_00567 7.8e-91 niaR S small molecule binding protein (contains 3H domain)
CMMIKGOF_00568 2.4e-87 niaX
CMMIKGOF_00569 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMMIKGOF_00570 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMMIKGOF_00571 1.3e-125 gntR1 K transcriptional
CMMIKGOF_00572 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CMMIKGOF_00573 4.8e-226 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
CMMIKGOF_00574 0.0 res_1 3.1.21.5 S Type III restriction
CMMIKGOF_00575 3e-21
CMMIKGOF_00577 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
CMMIKGOF_00578 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
CMMIKGOF_00579 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMMIKGOF_00580 1.2e-157 aatB ET ABC transporter substrate-binding protein
CMMIKGOF_00581 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_00582 4e-105 artQ P ABC transporter (Permease
CMMIKGOF_00583 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
CMMIKGOF_00584 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMMIKGOF_00585 4.5e-166 cpsY K Transcriptional regulator
CMMIKGOF_00586 6.2e-82 L transposition
CMMIKGOF_00587 1.6e-118 mur1 NU muramidase
CMMIKGOF_00588 2.1e-172 yeiH S Membrane
CMMIKGOF_00590 1.7e-08
CMMIKGOF_00591 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
CMMIKGOF_00592 1.3e-88 XK27_10720 D peptidase activity
CMMIKGOF_00593 1.2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
CMMIKGOF_00594 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
CMMIKGOF_00595 3.7e-157 glcU U Glucose uptake
CMMIKGOF_00596 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
CMMIKGOF_00597 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
CMMIKGOF_00598 4.2e-225 L Transposase
CMMIKGOF_00599 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
CMMIKGOF_00600 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMMIKGOF_00601 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMMIKGOF_00602 2.2e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CMMIKGOF_00603 1.2e-92 L Transposase
CMMIKGOF_00604 9.2e-89 L Transposase
CMMIKGOF_00605 0.0 copB 3.6.3.4 P P-type ATPase
CMMIKGOF_00606 1.1e-220 L Transposase, Mutator family
CMMIKGOF_00607 9.4e-43 K Cold-Shock Protein
CMMIKGOF_00608 5.4e-32 cspD K Cold shock protein domain
CMMIKGOF_00609 5.8e-41 pepD E dipeptidase activity
CMMIKGOF_00610 8.2e-120 pepD E Dipeptidase
CMMIKGOF_00611 8.7e-162 whiA K May be required for sporulation
CMMIKGOF_00612 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CMMIKGOF_00613 1.2e-163 rapZ S Displays ATPase and GTPase activities
CMMIKGOF_00614 2.8e-137 yejC S cyclic nucleotide-binding protein
CMMIKGOF_00615 2.2e-19 D nuclear chromosome segregation
CMMIKGOF_00616 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
CMMIKGOF_00617 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CMMIKGOF_00618 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CMMIKGOF_00619 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CMMIKGOF_00620 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CMMIKGOF_00621 3e-13
CMMIKGOF_00622 2.4e-30
CMMIKGOF_00623 1.5e-07
CMMIKGOF_00624 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CMMIKGOF_00625 4.7e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CMMIKGOF_00626 3.1e-81 ypmB S Protein conserved in bacteria
CMMIKGOF_00627 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CMMIKGOF_00628 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CMMIKGOF_00629 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
CMMIKGOF_00630 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
CMMIKGOF_00631 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CMMIKGOF_00632 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CMMIKGOF_00633 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CMMIKGOF_00634 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMMIKGOF_00635 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMMIKGOF_00636 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CMMIKGOF_00637 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CMMIKGOF_00638 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
CMMIKGOF_00639 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
CMMIKGOF_00640 2.1e-30 rpsT J rRNA binding
CMMIKGOF_00641 6.2e-249 L Transposase
CMMIKGOF_00642 9.8e-163 L Integrase core domain protein
CMMIKGOF_00643 2.3e-106 L Helix-turn-helix domain
CMMIKGOF_00644 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
CMMIKGOF_00645 3.1e-268 clcA P Chloride transporter, ClC family
CMMIKGOF_00646 8.9e-206 potD P spermidine putrescine ABC transporter
CMMIKGOF_00647 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
CMMIKGOF_00648 1.1e-220 L Transposase
CMMIKGOF_00649 1.2e-165 L integrase core domain
CMMIKGOF_00650 6.7e-122 L Helix-turn-helix domain
CMMIKGOF_00651 3.6e-88 T PhoQ Sensor
CMMIKGOF_00652 2.2e-43 T PhoQ Sensor
CMMIKGOF_00653 2.8e-40 T PhoQ Sensor
CMMIKGOF_00654 2.6e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMMIKGOF_00655 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMMIKGOF_00656 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CMMIKGOF_00657 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMMIKGOF_00658 1.7e-94 panT S ECF transporter, substrate-specific component
CMMIKGOF_00659 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CMMIKGOF_00660 9.6e-166 metF 1.5.1.20 E reductase
CMMIKGOF_00661 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMMIKGOF_00663 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CMMIKGOF_00664 0.0 3.6.3.8 P cation transport ATPase
CMMIKGOF_00665 2.5e-40 L Transposase
CMMIKGOF_00666 7.7e-19 L transposase activity
CMMIKGOF_00667 6.5e-54 L transposition
CMMIKGOF_00668 9.6e-32 L transposition
CMMIKGOF_00669 2.4e-33 L Integrase core domain protein
CMMIKGOF_00670 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMMIKGOF_00671 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMMIKGOF_00672 3.9e-237 dltB M Membrane protein involved in D-alanine export
CMMIKGOF_00673 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMMIKGOF_00674 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
CMMIKGOF_00675 0.0 XK27_10035 V abc transporter atp-binding protein
CMMIKGOF_00676 0.0 yfiB1 V abc transporter atp-binding protein
CMMIKGOF_00677 1.9e-101 pvaA M lytic transglycosylase activity
CMMIKGOF_00678 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
CMMIKGOF_00679 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMMIKGOF_00680 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMMIKGOF_00681 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMMIKGOF_00682 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMMIKGOF_00683 2.4e-112 tdk 2.7.1.21 F thymidine kinase
CMMIKGOF_00684 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMMIKGOF_00685 1.2e-154 gst O Glutathione S-transferase
CMMIKGOF_00686 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CMMIKGOF_00687 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMMIKGOF_00688 2e-45 rpmE2 J 50S ribosomal protein L31
CMMIKGOF_00689 9.4e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
CMMIKGOF_00690 5.5e-30
CMMIKGOF_00691 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMMIKGOF_00692 1.8e-135 divIVA D Cell division protein DivIVA
CMMIKGOF_00693 1.2e-143 ylmH T S4 RNA-binding domain
CMMIKGOF_00694 2.6e-34 yggT D integral membrane protein
CMMIKGOF_00695 6.8e-96 sepF D cell septum assembly
CMMIKGOF_00696 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CMMIKGOF_00697 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMMIKGOF_00698 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMMIKGOF_00699 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMMIKGOF_00700 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMMIKGOF_00701 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMMIKGOF_00703 0.0 typA T GTP-binding protein TypA
CMMIKGOF_00704 2.2e-179 glk 2.7.1.2 G Glucokinase
CMMIKGOF_00705 8.4e-28 yqgQ S protein conserved in bacteria
CMMIKGOF_00706 1.1e-80 perR P Belongs to the Fur family
CMMIKGOF_00707 3.5e-91 dps P Belongs to the Dps family
CMMIKGOF_00708 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CMMIKGOF_00709 2.3e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CMMIKGOF_00710 3e-50 L Transposase
CMMIKGOF_00711 2.7e-160 L Transposase
CMMIKGOF_00712 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CMMIKGOF_00713 4.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
CMMIKGOF_00714 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CMMIKGOF_00715 6.2e-56 S Domain of unknown function (DUF4430)
CMMIKGOF_00716 4.2e-75 S Psort location CytoplasmicMembrane, score
CMMIKGOF_00717 2.3e-130 htpX O Belongs to the peptidase M48B family
CMMIKGOF_00718 7.7e-92 lemA S LemA family
CMMIKGOF_00719 2e-76 spd F DNA RNA non-specific endonuclease
CMMIKGOF_00720 4.8e-61 spd F DNA RNA non-specific endonuclease
CMMIKGOF_00722 4.1e-50 S PD-(D/E)XK nuclease family transposase
CMMIKGOF_00723 3.6e-304 hsdM 2.1.1.72 V type I restriction-modification system
CMMIKGOF_00724 5.6e-130 S Protein conserved in bacteria
CMMIKGOF_00725 0.0 S KAP family P-loop domain
CMMIKGOF_00726 7.1e-127 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
CMMIKGOF_00727 0.0
CMMIKGOF_00728 1e-15
CMMIKGOF_00729 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CMMIKGOF_00730 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
CMMIKGOF_00731 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
CMMIKGOF_00732 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMMIKGOF_00733 2.7e-27 P Hemerythrin HHE cation binding domain protein
CMMIKGOF_00734 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
CMMIKGOF_00735 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMMIKGOF_00736 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CMMIKGOF_00737 7.5e-174 S hydrolase
CMMIKGOF_00738 7.6e-16
CMMIKGOF_00739 6.5e-163 M LysM domain
CMMIKGOF_00740 6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CMMIKGOF_00741 4.4e-24 S Protein of unknown function (DUF1643)
CMMIKGOF_00742 3.7e-161 haeIIIM 2.1.1.37 L C-5 cytosine-specific DNA methylase
CMMIKGOF_00743 6.2e-64
CMMIKGOF_00744 7.8e-19 pvuIIC K Helix-turn-helix domain
CMMIKGOF_00748 6.3e-38
CMMIKGOF_00749 2.1e-39
CMMIKGOF_00750 6.2e-99 L helicase
CMMIKGOF_00751 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
CMMIKGOF_00752 1.3e-11
CMMIKGOF_00753 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
CMMIKGOF_00754 1.1e-33 XK27_12190 S protein conserved in bacteria
CMMIKGOF_00756 8.4e-88 bioY S biotin synthase
CMMIKGOF_00757 3.4e-252 yegQ O Peptidase U32
CMMIKGOF_00758 2e-177 yegQ O Peptidase U32
CMMIKGOF_00760 5.5e-69 ytxH S General stress protein
CMMIKGOF_00762 9e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMMIKGOF_00763 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMMIKGOF_00764 6.4e-41 pspC KT PspC domain
CMMIKGOF_00765 0.0 yhgF K Transcriptional accessory protein
CMMIKGOF_00767 1.3e-154 XK27_03015 S permease
CMMIKGOF_00768 2.4e-147 ycgQ S TIGR03943 family
CMMIKGOF_00769 6.7e-198 S CRISPR-associated protein Csn2 subfamily St
CMMIKGOF_00770 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00771 9.3e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMMIKGOF_00772 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CMMIKGOF_00773 1.1e-94
CMMIKGOF_00774 6.3e-33 estA E GDSL-like Lipase/Acylhydrolase
CMMIKGOF_00775 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
CMMIKGOF_00776 1e-31 K Cro/C1-type HTH DNA-binding domain
CMMIKGOF_00777 4.7e-106
CMMIKGOF_00778 4.7e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMMIKGOF_00779 4.5e-97 mip S hydroperoxide reductase activity
CMMIKGOF_00780 2.4e-203 I acyl-CoA dehydrogenase
CMMIKGOF_00781 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
CMMIKGOF_00782 2e-237 msrR K Transcriptional regulator
CMMIKGOF_00783 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
CMMIKGOF_00784 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CMMIKGOF_00785 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CMMIKGOF_00786 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CMMIKGOF_00787 3.2e-53 yheA S Belongs to the UPF0342 family
CMMIKGOF_00788 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CMMIKGOF_00789 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CMMIKGOF_00790 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CMMIKGOF_00791 8.2e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMMIKGOF_00792 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CMMIKGOF_00793 2e-219 ywbD 2.1.1.191 J Methyltransferase
CMMIKGOF_00794 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CMMIKGOF_00796 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMMIKGOF_00797 1e-78 yueI S Protein of unknown function (DUF1694)
CMMIKGOF_00798 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CMMIKGOF_00799 6.6e-101 yyaQ V Protein conserved in bacteria
CMMIKGOF_00800 2.8e-28 yyaQ S YjbR
CMMIKGOF_00801 4.4e-183 ccpA K Catabolite control protein A
CMMIKGOF_00802 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CMMIKGOF_00803 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CMMIKGOF_00804 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMMIKGOF_00805 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMMIKGOF_00806 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMMIKGOF_00807 2e-33 secG U Preprotein translocase subunit SecG
CMMIKGOF_00808 9.5e-74 mdtG EGP Major facilitator Superfamily
CMMIKGOF_00809 6e-133 mdtG EGP Major facilitator Superfamily
CMMIKGOF_00810 2.4e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMMIKGOF_00811 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMMIKGOF_00812 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMMIKGOF_00813 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CMMIKGOF_00814 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMMIKGOF_00815 6.8e-53 licT K transcriptional antiterminator
CMMIKGOF_00816 5.8e-64 licT K transcriptional antiterminator
CMMIKGOF_00817 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMMIKGOF_00818 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CMMIKGOF_00819 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMMIKGOF_00820 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMMIKGOF_00821 7.5e-23 I Alpha/beta hydrolase family
CMMIKGOF_00822 1.5e-35 yugF I carboxylic ester hydrolase activity
CMMIKGOF_00823 1.5e-07
CMMIKGOF_00824 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CMMIKGOF_00825 1.1e-78 feoA P FeoA domain protein
CMMIKGOF_00826 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_00827 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CMMIKGOF_00828 1.3e-34 ykuJ S protein conserved in bacteria
CMMIKGOF_00829 4.5e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMMIKGOF_00830 0.0 clpE O Belongs to the ClpA ClpB family
CMMIKGOF_00831 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CMMIKGOF_00832 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
CMMIKGOF_00833 1.2e-53 S oxidoreductase
CMMIKGOF_00834 3e-51 S oxidoreductase
CMMIKGOF_00835 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
CMMIKGOF_00836 6.1e-70 M Pfam SNARE associated Golgi protein
CMMIKGOF_00837 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
CMMIKGOF_00840 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
CMMIKGOF_00843 4.8e-16 S Protein of unknown function (DUF2969)
CMMIKGOF_00844 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
CMMIKGOF_00845 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMMIKGOF_00846 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMMIKGOF_00847 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMMIKGOF_00848 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
CMMIKGOF_00849 1.4e-29 S Domain of unknown function (DUF1912)
CMMIKGOF_00850 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CMMIKGOF_00851 1.5e-250 mmuP E amino acid
CMMIKGOF_00852 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CMMIKGOF_00853 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMMIKGOF_00854 9.7e-22
CMMIKGOF_00855 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMMIKGOF_00856 2.9e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMMIKGOF_00857 1.7e-218 mvaS 2.3.3.10 I synthase
CMMIKGOF_00858 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CMMIKGOF_00859 1e-25 K hmm pf08876
CMMIKGOF_00860 1.5e-118 yqfA K protein, Hemolysin III
CMMIKGOF_00861 1.2e-22 S Protein of unknown function (DUF3114)
CMMIKGOF_00862 4.7e-165 S Protein of unknown function (DUF3114)
CMMIKGOF_00863 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CMMIKGOF_00864 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMMIKGOF_00865 4.9e-21 XK27_13030
CMMIKGOF_00866 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CMMIKGOF_00867 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CMMIKGOF_00868 1.1e-11 U protein secretion
CMMIKGOF_00869 2.1e-50 U protein secretion
CMMIKGOF_00870 3.5e-07 U protein secretion
CMMIKGOF_00872 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMMIKGOF_00873 2.5e-21
CMMIKGOF_00874 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CMMIKGOF_00875 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMMIKGOF_00876 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMMIKGOF_00877 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
CMMIKGOF_00878 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CMMIKGOF_00879 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CMMIKGOF_00880 4.6e-105 GBS0088 J protein conserved in bacteria
CMMIKGOF_00881 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMMIKGOF_00882 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CMMIKGOF_00883 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
CMMIKGOF_00884 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CMMIKGOF_00885 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMMIKGOF_00886 2.5e-113 S VIT family
CMMIKGOF_00887 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
CMMIKGOF_00888 2.7e-24
CMMIKGOF_00889 1e-27 XK27_00085 K Transcriptional
CMMIKGOF_00890 1e-195 yceA S Belongs to the UPF0176 family
CMMIKGOF_00891 5.4e-122 sagI S ABC-2 type transporter
CMMIKGOF_00892 2.8e-168 V ABC transporter
CMMIKGOF_00893 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CMMIKGOF_00894 2.5e-132 rr02 KT response regulator
CMMIKGOF_00895 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CMMIKGOF_00896 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMMIKGOF_00897 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMMIKGOF_00898 0.0 lmrA V abc transporter atp-binding protein
CMMIKGOF_00899 0.0 mdlB V abc transporter atp-binding protein
CMMIKGOF_00901 0.0 M the current gene model (or a revised gene model) may contain a
CMMIKGOF_00902 8.6e-51 M YSIRK type signal peptide
CMMIKGOF_00903 1.1e-40 S MucBP domain
CMMIKGOF_00904 3.2e-19 L COG COG2801 Transposase and inactivated derivatives
CMMIKGOF_00905 1.1e-32 L Integrase core domain
CMMIKGOF_00906 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMMIKGOF_00907 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMMIKGOF_00908 2.4e-27 ytrF V efflux transmembrane transporter activity
CMMIKGOF_00909 1.3e-10 V permease protein
CMMIKGOF_00910 9.9e-36 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMMIKGOF_00911 3.8e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMMIKGOF_00912 6.9e-18 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMMIKGOF_00913 3.4e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
CMMIKGOF_00914 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CMMIKGOF_00915 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CMMIKGOF_00916 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CMMIKGOF_00917 4.9e-227 pyrP F uracil Permease
CMMIKGOF_00918 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMMIKGOF_00919 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMMIKGOF_00920 9.8e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMMIKGOF_00921 1.4e-167 fhuR K transcriptional regulator (lysR family)
CMMIKGOF_00926 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMMIKGOF_00927 7e-144 pts33BCA G pts system
CMMIKGOF_00928 5.8e-71 pts33BCA G pts system
CMMIKGOF_00929 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
CMMIKGOF_00930 1.8e-254 cycA E permease
CMMIKGOF_00931 4.5e-39 ynzC S UPF0291 protein
CMMIKGOF_00932 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CMMIKGOF_00933 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CMMIKGOF_00934 6.1e-63 S membrane
CMMIKGOF_00935 1.5e-59
CMMIKGOF_00936 7.5e-26
CMMIKGOF_00937 1.8e-53
CMMIKGOF_00938 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMMIKGOF_00939 4.5e-69 nptA P sodium-dependent phosphate transmembrane transporter activity
CMMIKGOF_00940 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CMMIKGOF_00941 4.9e-106 mur1 NU mannosyl-glycoprotein
CMMIKGOF_00942 1.1e-53 glnB K Belongs to the P(II) protein family
CMMIKGOF_00943 2.6e-233 amt P Ammonium Transporter
CMMIKGOF_00944 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMMIKGOF_00945 9.5e-55 yabA L Involved in initiation control of chromosome replication
CMMIKGOF_00946 1.8e-134 yaaT S stage 0 sporulation protein
CMMIKGOF_00947 1.6e-160 holB 2.7.7.7 L dna polymerase iii
CMMIKGOF_00948 1.1e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMMIKGOF_00949 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMMIKGOF_00950 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMMIKGOF_00951 2.8e-230 ftsW D Belongs to the SEDS family
CMMIKGOF_00952 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CMMIKGOF_00953 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMMIKGOF_00954 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMMIKGOF_00955 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMMIKGOF_00956 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMMIKGOF_00957 3.3e-78 atpF C ATP synthase F(0) sector subunit b
CMMIKGOF_00958 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
CMMIKGOF_00959 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMMIKGOF_00960 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMMIKGOF_00961 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMMIKGOF_00962 1.1e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CMMIKGOF_00963 8.9e-14 coiA 3.6.4.12 S Competence protein
CMMIKGOF_00964 2.2e-15 T peptidase
CMMIKGOF_00965 5.5e-153 rarD S Transporter
CMMIKGOF_00966 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMMIKGOF_00967 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CMMIKGOF_00968 2e-131 yxkH G deacetylase
CMMIKGOF_00969 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CMMIKGOF_00970 2.7e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CMMIKGOF_00971 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMMIKGOF_00972 3.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CMMIKGOF_00973 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CMMIKGOF_00974 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CMMIKGOF_00975 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
CMMIKGOF_00976 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
CMMIKGOF_00977 1.5e-152 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CMMIKGOF_00978 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CMMIKGOF_00979 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMMIKGOF_00980 9.9e-163 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CMMIKGOF_00981 3.9e-125 yrrM 2.1.1.104 S O-Methyltransferase
CMMIKGOF_00982 0.0 pepF E oligoendopeptidase F
CMMIKGOF_00983 1.4e-186 coiA 3.6.4.12 S Competence protein
CMMIKGOF_00984 9.2e-164 K transcriptional regulator (lysR family)
CMMIKGOF_00985 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMMIKGOF_00989 1e-190 phoH T phosphate starvation-inducible protein PhoH
CMMIKGOF_00990 2.3e-61 rlpA M LysM domain protein
CMMIKGOF_00991 6.7e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
CMMIKGOF_00992 7.4e-35 yozE S Belongs to the UPF0346 family
CMMIKGOF_00993 5.3e-161 cvfB S Protein conserved in bacteria
CMMIKGOF_00994 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMMIKGOF_00995 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CMMIKGOF_00996 3.2e-78 sptS 2.7.13.3 T Histidine kinase
CMMIKGOF_00997 2.2e-18 K Acetyltransferase (GNAT) family
CMMIKGOF_00998 0.0 lmrA2 V abc transporter atp-binding protein
CMMIKGOF_00999 0.0 lmrA1 V abc transporter atp-binding protein
CMMIKGOF_01000 1.9e-77 K DNA-binding transcription factor activity
CMMIKGOF_01001 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMMIKGOF_01002 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CMMIKGOF_01003 1.3e-58 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CMMIKGOF_01004 1.6e-137 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CMMIKGOF_01005 2.1e-137 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CMMIKGOF_01006 1.6e-24 U response to pH
CMMIKGOF_01007 0.0 yfmR S abc transporter atp-binding protein
CMMIKGOF_01008 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMMIKGOF_01009 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMMIKGOF_01010 5.8e-144 XK27_08360 S EDD domain protein, DegV family
CMMIKGOF_01011 2.6e-64 WQ51_03320 S cog cog4835
CMMIKGOF_01012 2e-126 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMMIKGOF_01013 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CMMIKGOF_01014 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
CMMIKGOF_01015 6.4e-29 2.3.1.128 K acetyltransferase
CMMIKGOF_01016 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CMMIKGOF_01017 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CMMIKGOF_01018 1.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMMIKGOF_01019 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CMMIKGOF_01021 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMMIKGOF_01022 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMMIKGOF_01023 0.0 fruA 2.7.1.202 G phosphotransferase system
CMMIKGOF_01024 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMMIKGOF_01025 5.5e-122 fruR K transcriptional
CMMIKGOF_01026 1.8e-84 L Transposase
CMMIKGOF_01027 7.3e-204 rny D Endoribonuclease that initiates mRNA decay
CMMIKGOF_01028 1.2e-116 3.1.21.3 V PFAM restriction modification system DNA specificity domain
CMMIKGOF_01029 2.1e-296 hsdM 2.1.1.72 V HsdM N-terminal domain
CMMIKGOF_01030 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
CMMIKGOF_01031 4.1e-26
CMMIKGOF_01032 1.7e-38 L transposase activity
CMMIKGOF_01033 5.5e-98 L transposition
CMMIKGOF_01034 1.5e-27 S Antidote-toxin recognition MazE, bacterial antitoxin
CMMIKGOF_01038 1.4e-60 S Bacterial PH domain
CMMIKGOF_01039 1.1e-65 tnp L Transposase
CMMIKGOF_01040 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMMIKGOF_01041 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CMMIKGOF_01042 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMMIKGOF_01043 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CMMIKGOF_01044 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMMIKGOF_01045 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMMIKGOF_01046 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMMIKGOF_01047 1.6e-126 IQ reductase
CMMIKGOF_01048 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CMMIKGOF_01049 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CMMIKGOF_01050 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMMIKGOF_01051 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMMIKGOF_01052 4e-72 marR K Transcriptional regulator, MarR family
CMMIKGOF_01053 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CMMIKGOF_01054 5.6e-115 S Haloacid dehalogenase-like hydrolase
CMMIKGOF_01055 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMMIKGOF_01056 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
CMMIKGOF_01057 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMMIKGOF_01058 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
CMMIKGOF_01059 1.3e-101 ygaC J Belongs to the UPF0374 family
CMMIKGOF_01060 6.4e-108 S Domain of unknown function (DUF1803)
CMMIKGOF_01061 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
CMMIKGOF_01069 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMMIKGOF_01070 4.4e-123 comFC S Competence protein
CMMIKGOF_01071 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CMMIKGOF_01072 1.1e-110 yvyE 3.4.13.9 S YigZ family
CMMIKGOF_01073 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMMIKGOF_01074 3.3e-43 acuB S IMP dehydrogenase activity
CMMIKGOF_01075 2.8e-70 acuB S IMP dehydrogenase activity
CMMIKGOF_01076 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CMMIKGOF_01077 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CMMIKGOF_01078 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
CMMIKGOF_01079 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
CMMIKGOF_01080 4.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CMMIKGOF_01081 7.1e-46 ylbG S UPF0298 protein
CMMIKGOF_01082 3.4e-74 ylbF S Belongs to the UPF0342 family
CMMIKGOF_01083 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMMIKGOF_01084 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMMIKGOF_01086 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CMMIKGOF_01087 1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
CMMIKGOF_01088 6e-89 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CMMIKGOF_01089 2.2e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CMMIKGOF_01090 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMMIKGOF_01091 3e-212 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CMMIKGOF_01092 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
CMMIKGOF_01093 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
CMMIKGOF_01094 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMMIKGOF_01095 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMMIKGOF_01096 1.4e-41 ylxQ J ribosomal protein
CMMIKGOF_01097 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CMMIKGOF_01098 3.1e-212 nusA K Participates in both transcription termination and antitermination
CMMIKGOF_01099 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
CMMIKGOF_01100 2.5e-220 brpA K Transcriptional
CMMIKGOF_01101 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
CMMIKGOF_01102 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CMMIKGOF_01103 2.1e-247 pbuO S permease
CMMIKGOF_01104 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CMMIKGOF_01105 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CMMIKGOF_01106 1.1e-181 manL 2.7.1.191 G pts system
CMMIKGOF_01107 1.7e-116 manM G pts system
CMMIKGOF_01108 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
CMMIKGOF_01109 6.5e-63 manO S protein conserved in bacteria
CMMIKGOF_01110 1.1e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMMIKGOF_01111 7.8e-28 L transposase activity
CMMIKGOF_01112 5.7e-23 L Transposase
CMMIKGOF_01113 3.4e-50 L transposition
CMMIKGOF_01114 3e-27 L Integrase core domain protein
CMMIKGOF_01115 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
CMMIKGOF_01116 1.2e-34
CMMIKGOF_01117 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CMMIKGOF_01118 8.9e-167 dnaI L Primosomal protein DnaI
CMMIKGOF_01119 1.9e-217 dnaB L Replication initiation and membrane attachment
CMMIKGOF_01120 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMMIKGOF_01121 3e-276 T PhoQ Sensor
CMMIKGOF_01122 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMMIKGOF_01123 2e-89 yceD K metal-binding, possibly nucleic acid-binding protein
CMMIKGOF_01124 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CMMIKGOF_01125 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
CMMIKGOF_01126 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
CMMIKGOF_01127 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
CMMIKGOF_01128 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMMIKGOF_01129 1.2e-149 cbiQ P cobalt transport
CMMIKGOF_01130 0.0 ykoD P abc transporter atp-binding protein
CMMIKGOF_01131 9.4e-95 S UPF0397 protein
CMMIKGOF_01132 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CMMIKGOF_01133 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CMMIKGOF_01134 3e-98 metI P ABC transporter (Permease
CMMIKGOF_01135 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMMIKGOF_01136 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
CMMIKGOF_01137 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
CMMIKGOF_01138 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CMMIKGOF_01139 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
CMMIKGOF_01140 4e-153 ET amino acid transport
CMMIKGOF_01141 3.8e-205 EGP Transmembrane secretion effector
CMMIKGOF_01142 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
CMMIKGOF_01143 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMMIKGOF_01144 1e-116 ET amino acid transport
CMMIKGOF_01145 7.4e-23 ET amino acid transport
CMMIKGOF_01146 1.6e-131 cbiO P ABC transporter
CMMIKGOF_01147 1.7e-137 P cobalt transport protein
CMMIKGOF_01148 3.3e-175 cbiM P PDGLE domain
CMMIKGOF_01149 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CMMIKGOF_01150 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CMMIKGOF_01151 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CMMIKGOF_01152 6.6e-78 ureE O enzyme active site formation
CMMIKGOF_01153 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CMMIKGOF_01154 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CMMIKGOF_01155 3.8e-45 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CMMIKGOF_01156 6.8e-95 ureI S AmiS/UreI family transporter
CMMIKGOF_01157 1.4e-54 S Domain of unknown function (DUF4173)
CMMIKGOF_01158 6.7e-36 S Domain of unknown function (DUF4173)
CMMIKGOF_01159 3.7e-51 yhaI L Membrane
CMMIKGOF_01160 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMMIKGOF_01161 1.6e-25 V protein secretion by the type I secretion system
CMMIKGOF_01162 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMMIKGOF_01163 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMMIKGOF_01164 1.2e-32 V protein secretion by the type I secretion system
CMMIKGOF_01165 9.5e-161 K sequence-specific DNA binding
CMMIKGOF_01166 3.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CMMIKGOF_01167 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMMIKGOF_01168 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMMIKGOF_01169 6.5e-246 trkA P Potassium transporter peripheral membrane component
CMMIKGOF_01170 2.1e-258 trkH P Cation transport protein
CMMIKGOF_01171 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CMMIKGOF_01172 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMMIKGOF_01173 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMMIKGOF_01174 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMMIKGOF_01175 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CMMIKGOF_01176 5.4e-86 ykuL S CBS domain
CMMIKGOF_01177 3.5e-99 XK27_09740 S Phosphoesterase
CMMIKGOF_01178 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMMIKGOF_01179 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMMIKGOF_01180 7.6e-36 yneF S UPF0154 protein
CMMIKGOF_01181 3.7e-91 K transcriptional regulator
CMMIKGOF_01182 2.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMMIKGOF_01185 1.5e-97 ybhL S Belongs to the BI1 family
CMMIKGOF_01186 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CMMIKGOF_01187 1.9e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMMIKGOF_01188 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CMMIKGOF_01189 1.1e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMMIKGOF_01190 1.1e-86 L Integrase core domain protein
CMMIKGOF_01191 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMMIKGOF_01192 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMMIKGOF_01193 3.3e-80 XK27_09675 K -acetyltransferase
CMMIKGOF_01194 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CMMIKGOF_01195 2.5e-23
CMMIKGOF_01196 2.9e-41 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CMMIKGOF_01197 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CMMIKGOF_01198 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CMMIKGOF_01199 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CMMIKGOF_01200 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMMIKGOF_01201 9.8e-94 ypsA S Belongs to the UPF0398 family
CMMIKGOF_01202 1.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMMIKGOF_01203 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMMIKGOF_01204 3.7e-09 L Transposase
CMMIKGOF_01205 1.5e-203 L Transposase
CMMIKGOF_01206 5.1e-259 pepC 3.4.22.40 E aminopeptidase
CMMIKGOF_01207 3.2e-77 yhaI L Membrane
CMMIKGOF_01208 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMMIKGOF_01209 2.8e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMMIKGOF_01210 2.1e-140 S COG1073 Hydrolases of the alpha beta superfamily
CMMIKGOF_01211 2.6e-76 S thiolester hydrolase activity
CMMIKGOF_01213 3.8e-40 K transcriptional
CMMIKGOF_01214 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIKGOF_01215 3.1e-136 glcR K transcriptional regulator (DeoR family)
CMMIKGOF_01216 1.1e-34 cof Q phosphatase activity
CMMIKGOF_01217 3.9e-54 cof Q phosphatase activity
CMMIKGOF_01218 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CMMIKGOF_01219 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CMMIKGOF_01220 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
CMMIKGOF_01221 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMMIKGOF_01222 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMMIKGOF_01223 4.4e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMMIKGOF_01224 2.9e-54 S TM2 domain
CMMIKGOF_01225 9.4e-44
CMMIKGOF_01227 7.4e-48 L transposition
CMMIKGOF_01228 6e-45 L Transposase
CMMIKGOF_01229 1.6e-22 L transposase activity
CMMIKGOF_01230 3.8e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMMIKGOF_01231 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMMIKGOF_01232 5.2e-142 cmpC S abc transporter atp-binding protein
CMMIKGOF_01233 0.0 WQ51_06230 S ABC transporter substrate binding protein
CMMIKGOF_01234 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMMIKGOF_01235 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CMMIKGOF_01236 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
CMMIKGOF_01237 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMMIKGOF_01238 9.8e-50 yajC U protein transport
CMMIKGOF_01239 1.9e-127 yeeN K transcriptional regulatory protein
CMMIKGOF_01240 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
CMMIKGOF_01241 2.1e-168 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CMMIKGOF_01242 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMMIKGOF_01243 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
CMMIKGOF_01244 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
CMMIKGOF_01245 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CMMIKGOF_01246 2.5e-128 adcB P ABC transporter (Permease
CMMIKGOF_01247 6.4e-136 adcC P ABC transporter, ATP-binding protein
CMMIKGOF_01248 3.1e-72 adcR K transcriptional
CMMIKGOF_01249 1.9e-223 EGP Major facilitator Superfamily
CMMIKGOF_01250 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMMIKGOF_01251 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMMIKGOF_01252 8.3e-23
CMMIKGOF_01253 3.4e-62 oppF P Belongs to the ABC transporter superfamily
CMMIKGOF_01254 7.5e-62 oppF P Belongs to the ABC transporter superfamily
CMMIKGOF_01255 3.1e-43 oppD P Belongs to the ABC transporter superfamily
CMMIKGOF_01256 1.2e-62 oppD P Belongs to the ABC transporter superfamily
CMMIKGOF_01257 2.5e-32 oppD P Belongs to the ABC transporter superfamily
CMMIKGOF_01258 3e-27 oppD P Belongs to the ABC transporter superfamily
CMMIKGOF_01259 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMMIKGOF_01260 1.6e-73 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMMIKGOF_01261 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMMIKGOF_01262 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMMIKGOF_01263 2e-138 oppA E ABC transporter substrate-binding protein
CMMIKGOF_01264 7e-10 oppA E ABC transporter substrate-binding protein
CMMIKGOF_01265 2.2e-273 sufB O assembly protein SufB
CMMIKGOF_01266 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
CMMIKGOF_01267 1.7e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMMIKGOF_01268 4.1e-234 sufD O assembly protein SufD
CMMIKGOF_01269 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CMMIKGOF_01270 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
CMMIKGOF_01271 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMMIKGOF_01272 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CMMIKGOF_01273 1.8e-276 glnP P ABC transporter
CMMIKGOF_01274 1e-123 glnQ E abc transporter atp-binding protein
CMMIKGOF_01275 5e-94 V VanZ like family
CMMIKGOF_01276 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMMIKGOF_01277 6.5e-202 yhjX P Major Facilitator
CMMIKGOF_01278 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CMMIKGOF_01279 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMMIKGOF_01280 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMMIKGOF_01281 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CMMIKGOF_01282 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CMMIKGOF_01283 4.4e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CMMIKGOF_01284 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CMMIKGOF_01285 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMMIKGOF_01286 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMMIKGOF_01287 2.4e-83 nrdI F Belongs to the NrdI family
CMMIKGOF_01288 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CMMIKGOF_01289 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CMMIKGOF_01290 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMMIKGOF_01291 3.8e-176 prmA J Ribosomal protein L11 methyltransferase
CMMIKGOF_01292 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CMMIKGOF_01293 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
CMMIKGOF_01294 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMMIKGOF_01295 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMMIKGOF_01296 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMMIKGOF_01297 9.3e-150 ykuT M mechanosensitive ion channel
CMMIKGOF_01298 1.6e-77 sigH K DNA-templated transcription, initiation
CMMIKGOF_01299 1e-84
CMMIKGOF_01300 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CMMIKGOF_01301 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CMMIKGOF_01314 3.8e-31 hmpT S membrane
CMMIKGOF_01315 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CMMIKGOF_01316 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMMIKGOF_01317 1.1e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMMIKGOF_01318 8.4e-281 dnaK O Heat shock 70 kDa protein
CMMIKGOF_01319 1.8e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMMIKGOF_01320 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMMIKGOF_01321 1.3e-102 acmA 3.2.1.17 NU amidase activity
CMMIKGOF_01322 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CMMIKGOF_01323 1.1e-37 ais G alpha-ribazole phosphatase activity
CMMIKGOF_01324 8.7e-243 XK27_08635 S UPF0210 protein
CMMIKGOF_01325 6.1e-39 gcvR T UPF0237 protein
CMMIKGOF_01326 2.5e-58 capA M Bacterial capsule synthesis protein
CMMIKGOF_01327 1.6e-108 capA M Bacterial capsule synthesis protein
CMMIKGOF_01328 1.3e-41 capA M Bacterial capsule synthesis protein PGA_cap
CMMIKGOF_01329 5.7e-91 tnp L Transposase
CMMIKGOF_01330 3.4e-75 isp2 S pathogenesis
CMMIKGOF_01332 4.9e-173
CMMIKGOF_01333 1.8e-38 S Helix-turn-helix domain
CMMIKGOF_01334 7.4e-225 int L Belongs to the 'phage' integrase family
CMMIKGOF_01335 5.9e-91 3.6.4.12 K Divergent AAA domain protein
CMMIKGOF_01336 5.9e-24 3.6.4.12
CMMIKGOF_01337 4.3e-183 EGP Major facilitator Superfamily
CMMIKGOF_01338 2.4e-231 spaC2 V Lanthionine synthetase C family protein
CMMIKGOF_01339 0.0 S Lantibiotic dehydratase, C terminus
CMMIKGOF_01341 1.5e-35 K sequence-specific DNA binding
CMMIKGOF_01342 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CMMIKGOF_01343 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMMIKGOF_01344 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMMIKGOF_01345 1.8e-31 K helix-turn-helix
CMMIKGOF_01347 3.4e-155 degV S DegV family
CMMIKGOF_01348 1e-84 yacP S RNA-binding protein containing a PIN domain
CMMIKGOF_01349 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMMIKGOF_01352 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMMIKGOF_01353 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMMIKGOF_01354 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
CMMIKGOF_01355 6.9e-144 S SseB protein N-terminal domain
CMMIKGOF_01356 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CMMIKGOF_01357 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_01358 1.2e-165 L integrase core domain
CMMIKGOF_01359 2.5e-121 L Transposase
CMMIKGOF_01360 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_01361 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMMIKGOF_01362 0.0 clpC O Belongs to the ClpA ClpB family
CMMIKGOF_01363 6.2e-76 ctsR K Belongs to the CtsR family
CMMIKGOF_01364 1.1e-83 S Putative small multi-drug export protein
CMMIKGOF_01365 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMMIKGOF_01366 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
CMMIKGOF_01368 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CMMIKGOF_01369 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
CMMIKGOF_01371 6.4e-41 L transposition
CMMIKGOF_01372 3.4e-88 L Integrase core domain protein
CMMIKGOF_01373 3.5e-97 S reductase
CMMIKGOF_01374 2.6e-55 badR K DNA-binding transcription factor activity
CMMIKGOF_01375 5.5e-36 XK27_02060 S Transglycosylase associated protein
CMMIKGOF_01376 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CMMIKGOF_01377 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMMIKGOF_01382 1.9e-07
CMMIKGOF_01385 2.6e-10
CMMIKGOF_01391 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CMMIKGOF_01392 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMMIKGOF_01393 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
CMMIKGOF_01394 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CMMIKGOF_01395 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMMIKGOF_01397 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMMIKGOF_01399 6.5e-63 KT phosphorelay signal transduction system
CMMIKGOF_01400 1.9e-80 S Protein of unknown function (DUF3021)
CMMIKGOF_01401 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMMIKGOF_01402 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CMMIKGOF_01403 8.2e-70 argR K Regulates arginine biosynthesis genes
CMMIKGOF_01404 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CMMIKGOF_01405 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMMIKGOF_01406 1.2e-137 1.1.1.169 H Ketopantoate reductase
CMMIKGOF_01407 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMMIKGOF_01408 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMMIKGOF_01409 2e-241 purD 6.3.4.13 F Belongs to the GARS family
CMMIKGOF_01410 2.3e-161 S CHAP domain
CMMIKGOF_01411 2e-32 L Integrase core domain protein
CMMIKGOF_01412 3.5e-50 L transposition
CMMIKGOF_01413 1e-90 L transposase activity
CMMIKGOF_01414 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CMMIKGOF_01415 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMMIKGOF_01416 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CMMIKGOF_01417 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMMIKGOF_01418 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMMIKGOF_01419 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CMMIKGOF_01420 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMMIKGOF_01421 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMMIKGOF_01422 7e-144 recO L Involved in DNA repair and RecF pathway recombination
CMMIKGOF_01423 2.9e-218 araT 2.6.1.1 E Aminotransferase
CMMIKGOF_01424 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMMIKGOF_01425 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
CMMIKGOF_01426 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CMMIKGOF_01427 1.3e-140 mreC M Involved in formation and maintenance of cell shape
CMMIKGOF_01433 5.3e-11
CMMIKGOF_01446 4.2e-29 L transposition
CMMIKGOF_01447 2.5e-23 L Transposase
CMMIKGOF_01448 5.5e-46 L transposase activity
CMMIKGOF_01449 4e-50 L Transposase
CMMIKGOF_01450 8.7e-84 L Transposase
CMMIKGOF_01451 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMMIKGOF_01452 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMMIKGOF_01453 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMMIKGOF_01454 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CMMIKGOF_01456 2.7e-61 divIC D Septum formation initiator
CMMIKGOF_01457 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CMMIKGOF_01458 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMMIKGOF_01459 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMMIKGOF_01460 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMMIKGOF_01461 1.1e-29 yyzM S Protein conserved in bacteria
CMMIKGOF_01462 1.2e-51 L Transposase
CMMIKGOF_01463 4.8e-28 L Helix-turn-helix domain of transposase family ISL3
CMMIKGOF_01464 6.3e-111 L Transposase
CMMIKGOF_01465 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMMIKGOF_01466 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMMIKGOF_01467 1.3e-134 parB K Belongs to the ParB family
CMMIKGOF_01468 2.1e-135 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CMMIKGOF_01469 4.9e-32 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CMMIKGOF_01470 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMMIKGOF_01471 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
CMMIKGOF_01475 0.0 XK27_10405 S Bacterial membrane protein YfhO
CMMIKGOF_01476 6.7e-306 ybiT S abc transporter atp-binding protein
CMMIKGOF_01477 1.1e-153 yvjA S membrane
CMMIKGOF_01478 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CMMIKGOF_01479 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CMMIKGOF_01480 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMMIKGOF_01481 3.1e-44 yaaA S S4 domain protein YaaA
CMMIKGOF_01482 1.4e-234 ymfF S Peptidase M16
CMMIKGOF_01483 1.4e-242 ymfH S Peptidase M16
CMMIKGOF_01484 3.7e-138 ymfM S sequence-specific DNA binding
CMMIKGOF_01485 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMMIKGOF_01486 2.2e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMMIKGOF_01487 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMMIKGOF_01488 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMMIKGOF_01489 5.3e-85 lytE M LysM domain protein
CMMIKGOF_01490 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
CMMIKGOF_01491 0.0 S Bacterial membrane protein, YfhO
CMMIKGOF_01492 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMMIKGOF_01493 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMMIKGOF_01494 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CMMIKGOF_01495 3.9e-70 rplI J binds to the 23S rRNA
CMMIKGOF_01496 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMMIKGOF_01497 1.5e-46 veg S Biofilm formation stimulator VEG
CMMIKGOF_01498 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMMIKGOF_01499 2.7e-08
CMMIKGOF_01500 4.8e-55 ypaA M Membrane
CMMIKGOF_01501 6.4e-96 XK27_06935 K transcriptional regulator
CMMIKGOF_01502 3.9e-161 XK27_06930 V domain protein
CMMIKGOF_01503 2.2e-106 S Putative adhesin
CMMIKGOF_01504 4.3e-61 L COG2801 Transposase and inactivated derivatives
CMMIKGOF_01505 1e-45 M Glycosyltransferase family 92
CMMIKGOF_01506 6.1e-36 L COG2801 Transposase and inactivated derivatives
CMMIKGOF_01507 2.7e-77 L transposition
CMMIKGOF_01508 3.9e-94 L Transposase
CMMIKGOF_01509 3.2e-89 L Transposase
CMMIKGOF_01510 1.6e-49 E IrrE N-terminal-like domain
CMMIKGOF_01511 3e-55 E IrrE N-terminal-like domain
CMMIKGOF_01512 7.1e-09 K Peptidase S24-like protein
CMMIKGOF_01513 7.3e-48 K Peptidase S24-like protein
CMMIKGOF_01514 3.6e-34 L Transposase
CMMIKGOF_01515 1.1e-11 K CsbD-like
CMMIKGOF_01516 1.1e-71 M Protein conserved in bacteria
CMMIKGOF_01517 1.8e-23 S Small integral membrane protein
CMMIKGOF_01518 3.1e-101
CMMIKGOF_01519 3.7e-27 S Membrane
CMMIKGOF_01521 2.5e-96 S Hydrophobic domain protein
CMMIKGOF_01522 2.6e-49 yegS 2.7.1.107 I lipid kinase activity
CMMIKGOF_01524 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMMIKGOF_01525 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CMMIKGOF_01526 9.2e-36 metE 2.1.1.14 E Methionine synthase
CMMIKGOF_01527 7.6e-64 metE 2.1.1.14 E Methionine synthase
CMMIKGOF_01528 5.7e-52 metE 2.1.1.14 E Methionine synthase
CMMIKGOF_01529 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
CMMIKGOF_01531 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMMIKGOF_01532 9.9e-169 XK27_01785 S cog cog1284
CMMIKGOF_01533 1.8e-147 yaaA S Belongs to the UPF0246 family
CMMIKGOF_01534 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMMIKGOF_01535 2.6e-91 XK27_10930 K acetyltransferase
CMMIKGOF_01536 7.5e-14
CMMIKGOF_01537 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CMMIKGOF_01538 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
CMMIKGOF_01539 4.2e-44 yrzB S Belongs to the UPF0473 family
CMMIKGOF_01540 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMMIKGOF_01541 2.8e-44 yrzL S Belongs to the UPF0297 family
CMMIKGOF_01542 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CMMIKGOF_01543 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CMMIKGOF_01545 3.5e-216 int L Belongs to the 'phage' integrase family
CMMIKGOF_01546 4.6e-17 S Domain of unknown function (DUF3173)
CMMIKGOF_01547 1.4e-107 L Replication initiation factor
CMMIKGOF_01548 1.3e-36 L Replication initiation factor
CMMIKGOF_01549 1.7e-90 K sequence-specific DNA binding
CMMIKGOF_01550 5.1e-287 V ABC transporter transmembrane region
CMMIKGOF_01551 3.4e-191 C Radical SAM
CMMIKGOF_01552 6.3e-16 C Radical SAM
CMMIKGOF_01554 1.4e-127 Z012_04635 K sequence-specific DNA binding
CMMIKGOF_01555 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_01556 2.1e-280 V ABC transporter
CMMIKGOF_01557 0.0 KLT serine threonine protein kinase
CMMIKGOF_01558 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_01560 4.1e-147 L Transposase
CMMIKGOF_01561 1.4e-53 L Transposase
CMMIKGOF_01562 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMMIKGOF_01563 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMMIKGOF_01564 1.7e-35 XK27_09805 S MORN repeat protein
CMMIKGOF_01565 0.0 XK27_09800 I Acyltransferase
CMMIKGOF_01566 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMMIKGOF_01567 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CMMIKGOF_01568 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMMIKGOF_01569 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CMMIKGOF_01570 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMMIKGOF_01571 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMMIKGOF_01572 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMMIKGOF_01573 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMMIKGOF_01574 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMMIKGOF_01575 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMMIKGOF_01576 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CMMIKGOF_01577 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMMIKGOF_01578 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMMIKGOF_01579 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMMIKGOF_01580 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMMIKGOF_01581 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMMIKGOF_01582 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMMIKGOF_01583 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMMIKGOF_01584 4.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMMIKGOF_01585 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMMIKGOF_01586 2.5e-23 rpmD J ribosomal protein l30
CMMIKGOF_01587 4.4e-58 rplO J binds to the 23S rRNA
CMMIKGOF_01588 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMMIKGOF_01589 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMMIKGOF_01590 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMMIKGOF_01591 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CMMIKGOF_01592 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMMIKGOF_01593 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMMIKGOF_01594 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIKGOF_01595 3.3e-62 rplQ J ribosomal protein l17
CMMIKGOF_01596 1e-61 L PFAM Integrase, catalytic core
CMMIKGOF_01597 5.9e-33 L PFAM Integrase, catalytic core
CMMIKGOF_01598 3.3e-09 L PFAM Integrase, catalytic core
CMMIKGOF_01599 6.3e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
CMMIKGOF_01600 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
CMMIKGOF_01601 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
CMMIKGOF_01603 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
CMMIKGOF_01604 4.2e-72 L PFAM Integrase, catalytic core
CMMIKGOF_01606 9.8e-71 L Phage integrase family
CMMIKGOF_01607 2.4e-23 S phage tail tape measure protein
CMMIKGOF_01608 7.1e-130 S EcsC protein family
CMMIKGOF_01609 2e-20 S phage tail
CMMIKGOF_01610 1.8e-127 tnp L Transposase
CMMIKGOF_01613 3.3e-95 ywlG S Belongs to the UPF0340 family
CMMIKGOF_01614 8.6e-87 treR K trehalose operon
CMMIKGOF_01615 5.8e-21 treR K DNA-binding transcription factor activity
CMMIKGOF_01616 1.4e-54 treB 2.7.1.201 G PTS System
CMMIKGOF_01617 3.1e-36 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CMMIKGOF_01618 1.6e-114 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CMMIKGOF_01619 0.0 pepO 3.4.24.71 O Peptidase family M13
CMMIKGOF_01620 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
CMMIKGOF_01621 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMMIKGOF_01622 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMMIKGOF_01623 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
CMMIKGOF_01624 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMMIKGOF_01625 1.9e-278 thrC 4.2.3.1 E Threonine synthase
CMMIKGOF_01626 3.2e-226 norN V Mate efflux family protein
CMMIKGOF_01627 1.8e-57 asp S cog cog1302
CMMIKGOF_01628 3.2e-303 yloV S kinase related to dihydroxyacetone kinase
CMMIKGOF_01629 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CMMIKGOF_01630 4.4e-280 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CMMIKGOF_01631 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CMMIKGOF_01632 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
CMMIKGOF_01633 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CMMIKGOF_01634 4.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMMIKGOF_01635 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMMIKGOF_01636 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIKGOF_01637 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMMIKGOF_01638 2.9e-68 S cog cog4699
CMMIKGOF_01639 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CMMIKGOF_01640 3e-145 cglB NU type II secretion system
CMMIKGOF_01641 8.5e-43 comGC U Required for transformation and DNA binding
CMMIKGOF_01642 1.8e-57 cglD NU Competence protein
CMMIKGOF_01643 1.4e-15 NU Type II secretory pathway pseudopilin
CMMIKGOF_01644 1.5e-71 comGF U Competence protein ComGF
CMMIKGOF_01645 2e-12 comGF U Putative Competence protein ComGF
CMMIKGOF_01646 5.9e-177 ytxK 2.1.1.72 L DNA methylase
CMMIKGOF_01647 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMMIKGOF_01649 1.4e-33 V CAAX protease self-immunity
CMMIKGOF_01650 5e-67 V CAAX protease self-immunity
CMMIKGOF_01652 1.8e-111 S CAAX amino terminal protease family protein
CMMIKGOF_01653 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMMIKGOF_01654 4.7e-169 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CMMIKGOF_01655 4.1e-09 S Domain of unknown function (DUF4651)
CMMIKGOF_01656 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMMIKGOF_01657 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMMIKGOF_01658 1.3e-190 yeeE S Sulphur transport
CMMIKGOF_01659 6.4e-37 yeeD O sulfur carrier activity
CMMIKGOF_01660 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMMIKGOF_01661 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMMIKGOF_01664 2e-157 rrmA 2.1.1.187 Q methyltransferase
CMMIKGOF_01665 3.4e-64 S phosphatase activity
CMMIKGOF_01666 2.7e-48 S glycolate biosynthetic process
CMMIKGOF_01667 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMMIKGOF_01668 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMMIKGOF_01669 2e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMMIKGOF_01670 2.2e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CMMIKGOF_01671 1.1e-121 L Transposase
CMMIKGOF_01672 1.2e-165 L integrase core domain
CMMIKGOF_01673 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMMIKGOF_01674 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CMMIKGOF_01675 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
CMMIKGOF_01676 4.9e-54 fnt P Formate nitrite transporter
CMMIKGOF_01677 2.3e-141 XK27_09615 C reductase
CMMIKGOF_01678 9e-62 XK27_09615 C reductase
CMMIKGOF_01679 4.3e-77 XK27_09620 S reductase
CMMIKGOF_01680 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
CMMIKGOF_01681 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CMMIKGOF_01682 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMMIKGOF_01683 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
CMMIKGOF_01684 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
CMMIKGOF_01685 1.3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CMMIKGOF_01686 3.5e-50 S Protein of unknown function (DUF3397)
CMMIKGOF_01687 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMMIKGOF_01688 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMMIKGOF_01689 7.3e-69 amiA E transmembrane transport
CMMIKGOF_01690 6.7e-81 amiA E transmembrane transport
CMMIKGOF_01691 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMMIKGOF_01692 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMMIKGOF_01693 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
CMMIKGOF_01694 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMMIKGOF_01695 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMMIKGOF_01696 2e-186 jag S RNA-binding protein
CMMIKGOF_01697 1e-13 rpmH J Ribosomal protein L34
CMMIKGOF_01698 1.6e-249 L Transposase
CMMIKGOF_01699 5e-84 L Transposase
CMMIKGOF_01700 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMMIKGOF_01703 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
CMMIKGOF_01704 3.1e-10 L thioesterase
CMMIKGOF_01705 7.8e-143 S Macro domain protein
CMMIKGOF_01706 4.8e-51 trxA O Belongs to the thioredoxin family
CMMIKGOF_01707 2.5e-26 yccU S CoA-binding protein
CMMIKGOF_01708 1.4e-144 tatD L Hydrolase, tatd
CMMIKGOF_01709 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMMIKGOF_01710 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMMIKGOF_01712 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMMIKGOF_01713 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CMMIKGOF_01714 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
CMMIKGOF_01715 6.9e-173 rmuC S RmuC domain protein
CMMIKGOF_01716 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
CMMIKGOF_01717 1.1e-142 purR 2.4.2.7 F operon repressor
CMMIKGOF_01718 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMMIKGOF_01719 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMMIKGOF_01720 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMMIKGOF_01721 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMMIKGOF_01722 1.7e-111 L Transposase
CMMIKGOF_01723 1e-102 L Transposase
CMMIKGOF_01724 9.1e-83 L Integrase core domain protein
CMMIKGOF_01725 1.8e-56 L transposition
CMMIKGOF_01726 7.4e-23 L Transposase
CMMIKGOF_01727 1.9e-46 L transposase activity
CMMIKGOF_01728 3.2e-42 L Transposase
CMMIKGOF_01729 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CMMIKGOF_01730 8.9e-30
CMMIKGOF_01731 1.1e-12
CMMIKGOF_01732 1.3e-87 S Fusaric acid resistance protein-like
CMMIKGOF_01733 8.5e-63 glnR K Transcriptional regulator
CMMIKGOF_01734 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
CMMIKGOF_01735 2.7e-40 pscB M CHAP domain protein
CMMIKGOF_01736 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMMIKGOF_01737 2.5e-33 ykzG S Belongs to the UPF0356 family
CMMIKGOF_01738 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CMMIKGOF_01739 8.2e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CMMIKGOF_01740 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMMIKGOF_01741 1.3e-117 azlC E AzlC protein
CMMIKGOF_01742 2e-47 azlD E branched-chain amino acid
CMMIKGOF_01743 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMMIKGOF_01744 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMMIKGOF_01745 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMMIKGOF_01746 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CMMIKGOF_01747 1e-93 cvpA S toxin biosynthetic process
CMMIKGOF_01748 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMMIKGOF_01749 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMMIKGOF_01754 4.2e-230 mutY L A G-specific adenine glycosylase
CMMIKGOF_01755 1.9e-29 XK27_05745
CMMIKGOF_01757 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
CMMIKGOF_01758 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMMIKGOF_01759 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMMIKGOF_01761 3.1e-124 XK27_01040 S Pfam PF06570
CMMIKGOF_01762 2e-169 corA P COG0598 Mg2 and Co2 transporters
CMMIKGOF_01763 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CMMIKGOF_01765 1e-58 V 'abc transporter, ATP-binding protein
CMMIKGOF_01766 8e-44 V 'abc transporter, ATP-binding protein
CMMIKGOF_01768 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CMMIKGOF_01769 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
CMMIKGOF_01770 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMMIKGOF_01771 3.4e-62 yqhY S protein conserved in bacteria
CMMIKGOF_01772 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMMIKGOF_01773 7.5e-180 scrR K Transcriptional
CMMIKGOF_01774 1.2e-290 scrB 3.2.1.26 GH32 G invertase
CMMIKGOF_01775 0.0 scrA 2.7.1.211 G pts system
CMMIKGOF_01776 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CMMIKGOF_01777 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMMIKGOF_01779 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMMIKGOF_01780 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CMMIKGOF_01781 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CMMIKGOF_01782 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMMIKGOF_01783 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMMIKGOF_01784 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMMIKGOF_01785 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CMMIKGOF_01786 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
CMMIKGOF_01787 2.9e-18 yebC M Membrane
CMMIKGOF_01788 2.6e-80 yebC M Membrane
CMMIKGOF_01789 3.6e-66 KT response to antibiotic
CMMIKGOF_01790 5.2e-75 XK27_02470 K LytTr DNA-binding domain
CMMIKGOF_01791 2.6e-121 liaI S membrane
CMMIKGOF_01792 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CMMIKGOF_01793 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CMMIKGOF_01794 5.2e-125 S Protein of unknown function (DUF554)
CMMIKGOF_01795 8.1e-134 ecsA_2 V abc transporter atp-binding protein
CMMIKGOF_01796 2.6e-286 XK27_00765
CMMIKGOF_01797 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMMIKGOF_01798 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMMIKGOF_01799 4.5e-18 D nuclear chromosome segregation
CMMIKGOF_01800 8.7e-33 yhaI J Protein of unknown function (DUF805)
CMMIKGOF_01802 2.6e-30
CMMIKGOF_01803 7.4e-27
CMMIKGOF_01804 1.6e-65
CMMIKGOF_01805 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMMIKGOF_01806 4.3e-47 ftsL D cell division protein FtsL
CMMIKGOF_01807 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CMMIKGOF_01808 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMMIKGOF_01809 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMMIKGOF_01811 3.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CMMIKGOF_01812 1.2e-65 yutD J protein conserved in bacteria
CMMIKGOF_01813 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CMMIKGOF_01814 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
CMMIKGOF_01816 0.0 mdlA V abc transporter atp-binding protein
CMMIKGOF_01817 0.0 mdlB V abc transporter atp-binding protein
CMMIKGOF_01818 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMMIKGOF_01819 7.3e-237 mesE M Transport protein ComB
CMMIKGOF_01821 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
CMMIKGOF_01822 7.4e-135 agrA KT phosphorelay signal transduction system
CMMIKGOF_01826 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
CMMIKGOF_01833 6.7e-98 blpT
CMMIKGOF_01834 2.9e-28 blpT
CMMIKGOF_01835 3e-47 spiA K sequence-specific DNA binding
CMMIKGOF_01838 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMMIKGOF_01839 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CMMIKGOF_01840 5e-44 V CAAX protease self-immunity
CMMIKGOF_01841 4.6e-140 cppA E CppA N-terminal
CMMIKGOF_01842 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CMMIKGOF_01843 1.2e-117 ybbL S abc transporter atp-binding protein
CMMIKGOF_01844 1.5e-127 ybbM S transport system, permease component
CMMIKGOF_01845 2.9e-87 D nuclear chromosome segregation
CMMIKGOF_01846 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
CMMIKGOF_01847 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMMIKGOF_01848 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
CMMIKGOF_01849 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CMMIKGOF_01850 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMMIKGOF_01852 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CMMIKGOF_01853 1e-162 yxeN P ABC transporter (Permease
CMMIKGOF_01854 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_01855 1.9e-09 S Protein of unknown function (DUF4059)
CMMIKGOF_01856 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMMIKGOF_01857 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
CMMIKGOF_01858 5.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMMIKGOF_01859 2.2e-196 ylbL T Belongs to the peptidase S16 family
CMMIKGOF_01860 1.3e-184 yhcC S radical SAM protein
CMMIKGOF_01861 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
CMMIKGOF_01863 0.0 yjcE P NhaP-type Na H and K H antiporters
CMMIKGOF_01864 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CMMIKGOF_01865 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CMMIKGOF_01866 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMMIKGOF_01869 2.4e-75 XK27_03180 T universal stress protein
CMMIKGOF_01870 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CMMIKGOF_01871 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CMMIKGOF_01872 6.8e-101 pncA Q isochorismatase
CMMIKGOF_01873 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
CMMIKGOF_01874 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMMIKGOF_01875 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMMIKGOF_01876 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMMIKGOF_01877 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CMMIKGOF_01878 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMMIKGOF_01879 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMMIKGOF_01880 3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMMIKGOF_01881 1.2e-58
CMMIKGOF_01882 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CMMIKGOF_01883 1.8e-98 yqeG S hydrolase of the HAD superfamily
CMMIKGOF_01884 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CMMIKGOF_01885 3.5e-49 yhbY J RNA-binding protein
CMMIKGOF_01886 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMMIKGOF_01887 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CMMIKGOF_01888 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMMIKGOF_01889 2e-140 yqeM Q Methyltransferase domain protein
CMMIKGOF_01890 6.9e-206 ylbM S Belongs to the UPF0348 family
CMMIKGOF_01891 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CMMIKGOF_01892 3.2e-110
CMMIKGOF_01893 1.3e-56 S CD20-like family
CMMIKGOF_01894 2.3e-10
CMMIKGOF_01895 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CMMIKGOF_01896 2.3e-133 ecsA V abc transporter atp-binding protein
CMMIKGOF_01897 5.1e-182 ecsB U ABC transporter
CMMIKGOF_01898 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
CMMIKGOF_01899 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMMIKGOF_01901 7.7e-227 ytfP S Flavoprotein
CMMIKGOF_01902 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CMMIKGOF_01903 7.4e-64 XK27_02560 S cog cog2151
CMMIKGOF_01904 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
CMMIKGOF_01905 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
CMMIKGOF_01906 2.7e-129 K transcriptional regulator, MerR family
CMMIKGOF_01907 9.7e-28 L transposase activity
CMMIKGOF_01908 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMMIKGOF_01909 1.7e-24
CMMIKGOF_01910 0.0 ctpE P E1-E2 ATPase
CMMIKGOF_01911 4.6e-52
CMMIKGOF_01912 8.1e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
CMMIKGOF_01913 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMMIKGOF_01914 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CMMIKGOF_01915 1.9e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMMIKGOF_01916 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CMMIKGOF_01917 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CMMIKGOF_01918 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CMMIKGOF_01919 4.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CMMIKGOF_01920 2.7e-73 copY K Copper transport repressor, CopY TcrY family
CMMIKGOF_01921 0.0 copA 3.6.3.54 P P-type ATPase
CMMIKGOF_01922 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
CMMIKGOF_01923 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMMIKGOF_01924 1.7e-114 papP P ABC transporter (Permease
CMMIKGOF_01925 3.9e-106 P ABC transporter (Permease
CMMIKGOF_01926 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
CMMIKGOF_01927 1.1e-155 cjaA ET ABC transporter substrate-binding protein
CMMIKGOF_01931 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMMIKGOF_01932 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
CMMIKGOF_01933 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMMIKGOF_01934 1.4e-84 yjbB G Permeases of the major facilitator superfamily
CMMIKGOF_01935 2.4e-64 yjbB G Permeases of the major facilitator superfamily
CMMIKGOF_01936 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CMMIKGOF_01937 7.8e-100 thiT S Thiamine transporter
CMMIKGOF_01938 1.9e-62 yjqA S Bacterial PH domain
CMMIKGOF_01939 7.4e-145 corA P CorA-like protein
CMMIKGOF_01940 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMMIKGOF_01941 1e-41 yazA L endonuclease containing a URI domain
CMMIKGOF_01942 2.3e-139 yabB 2.1.1.223 L Methyltransferase
CMMIKGOF_01943 4.1e-22 nodB3 G polysaccharide deacetylase
CMMIKGOF_01944 1.7e-77 nodB3 G polysaccharide deacetylase
CMMIKGOF_01945 6.1e-71 plsC 2.3.1.51 I Acyltransferase
CMMIKGOF_01946 2.9e-57 plsC 2.3.1.51 I Acyltransferase
CMMIKGOF_01947 1.1e-23
CMMIKGOF_01948 2.8e-97
CMMIKGOF_01949 5.2e-56 V ABC-2 type transporter
CMMIKGOF_01950 4.1e-156 V AAA domain, putative AbiEii toxin, Type IV TA system
CMMIKGOF_01952 2.5e-139 C Iron-sulfur cluster-binding domain
CMMIKGOF_01953 2.7e-112 C 4Fe-4S single cluster domain
CMMIKGOF_01955 1.1e-140 Z012_04635 K Helix-turn-helix XRE-family like proteins
CMMIKGOF_01956 7.5e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CMMIKGOF_01957 0.0 comEC S Competence protein ComEC
CMMIKGOF_01958 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMMIKGOF_01959 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CMMIKGOF_01960 3.3e-231 ytoI K transcriptional regulator containing CBS domains
CMMIKGOF_01961 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CMMIKGOF_01962 7.4e-164 rbn E Belongs to the UPF0761 family
CMMIKGOF_01963 3.7e-85 ccl S cog cog4708
CMMIKGOF_01964 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMMIKGOF_01965 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CMMIKGOF_01966 1.9e-55 L Transposase
CMMIKGOF_01967 2.1e-74 S QueT transporter
CMMIKGOF_01968 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
CMMIKGOF_01969 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CMMIKGOF_01970 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CMMIKGOF_01971 4.1e-37 ylqC L Belongs to the UPF0109 family
CMMIKGOF_01972 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMMIKGOF_01973 0.0 ydaO E amino acid
CMMIKGOF_01974 1e-99 folE 3.5.4.16 F gtp cyclohydrolase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)