ORF_ID e_value Gene_name EC_number CAZy COGs Description
COCLMCBI_00001 1.1e-118 L COG4584 Transposase and inactivated derivatives
COCLMCBI_00002 3e-134 L DNA replication protein
COCLMCBI_00003 5.8e-19 S Protein of unknown function (DUF3054)
COCLMCBI_00005 3e-287 accD4 2.1.3.15, 6.4.1.3 I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COCLMCBI_00006 0.0 pks13 Q Polyketide synthase modules and related proteins
COCLMCBI_00007 0.0 fadD32 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_00008 5.9e-158 elrF S Cutinase
COCLMCBI_00009 1.3e-28
COCLMCBI_00010 0.0 csp1 M Trehalose corynomycolyl transferase
COCLMCBI_00011 3e-187 cmtB 2.3.1.122, 2.3.1.20 S esterase
COCLMCBI_00012 0.0 aftB GT89 M capsule polysaccharide biosynthetic process
COCLMCBI_00013 4.8e-174 ubiA 2.4.2.45 H Phosphoribose diphosphate decaprenyl-phosphate phosphoribosyltransferase
COCLMCBI_00014 1.1e-76 3.6.1.27 I Membrane-associated phospholipid phosphatase
COCLMCBI_00015 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferases
COCLMCBI_00016 8.9e-93 V HNH endonuclease
COCLMCBI_00018 1.1e-180 aftC 2.4.2.47 S Glycosyltransferase family 87
COCLMCBI_00019 3.7e-272 P NhaP-type Na H and K H antiporters
COCLMCBI_00020 1.4e-169 S Domain of unknown function (DUF4143)
COCLMCBI_00021 5.6e-34 Z012_07300 O Glutaredoxin-related protein
COCLMCBI_00022 2.1e-84 K BetI-type transcriptional repressor, C-terminal
COCLMCBI_00023 1.2e-102 O Sap, sulfolipid-1-addressing protein
COCLMCBI_00024 2.1e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
COCLMCBI_00025 0.0 lytC M protein potentially involved in peptidoglycan biosynthesis
COCLMCBI_00026 1.2e-280 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COCLMCBI_00027 1.7e-162 K Psort location Cytoplasmic, score
COCLMCBI_00028 1.8e-153 yidA S hydrolases of the HAD superfamily
COCLMCBI_00029 3.5e-157 plsC1 I Phosphate acyltransferases
COCLMCBI_00030 2.7e-146 plsC1 I Acyltransferase
COCLMCBI_00031 1.5e-214 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COCLMCBI_00032 8.2e-180 S Septum formation
COCLMCBI_00033 1.3e-60 S protein conserved in bacteria
COCLMCBI_00034 7.4e-115 pgmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
COCLMCBI_00035 1.7e-157 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
COCLMCBI_00036 7.3e-117 S metal-dependent membrane protease
COCLMCBI_00037 2.5e-161 lytR2 K function transcriptional attenuator common domain protein
COCLMCBI_00038 1e-241 proY E Gamma-aminobutyrate permease and related permeases
COCLMCBI_00039 6.5e-160 L Phage integrase family
COCLMCBI_00040 1.9e-19
COCLMCBI_00042 2.2e-296
COCLMCBI_00045 3.4e-64
COCLMCBI_00046 5.6e-101 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
COCLMCBI_00047 2.2e-38 ydeP5 K transcriptional regulator
COCLMCBI_00050 2.5e-161 cotF M PFAM Coat F domain
COCLMCBI_00051 6.7e-150 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COCLMCBI_00052 0.0 S membrane
COCLMCBI_00053 8.5e-136 msrA 1.8.4.11 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COCLMCBI_00054 1.4e-112 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COCLMCBI_00055 1.5e-190 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00056 4.8e-216 ynfM EGP Major facilitator Superfamily
COCLMCBI_00057 1.6e-274 S Nuclease, RecB family
COCLMCBI_00058 3.7e-66
COCLMCBI_00059 1.3e-106 hrrA T helix_turn_helix, Lux Regulon
COCLMCBI_00060 2.4e-170 hrrS T Histidine kinase
COCLMCBI_00061 1.1e-169 E GDSL-like Lipase/Acylhydrolase
COCLMCBI_00062 7.4e-161 yidC U inner membrane protein translocase component YidC
COCLMCBI_00063 1.9e-91 mcbR K Transcriptional regulator
COCLMCBI_00064 4.1e-19 ymgE S Transglycosylase associated protein
COCLMCBI_00065 8.1e-152 uspA1 T universal stress protein
COCLMCBI_00066 1.4e-08
COCLMCBI_00067 3.3e-162 rluA 5.4.99.28, 5.4.99.29 J Pseudouridylate synthases, 23S RNA-specific
COCLMCBI_00069 2.6e-149 insK L Transposase and inactivated derivatives
COCLMCBI_00070 1.4e-134 L DNA replication protein
COCLMCBI_00071 2.4e-127 L COG4584 Transposase and inactivated derivatives
COCLMCBI_00072 1.8e-33 L Helix-turn-helix domain
COCLMCBI_00073 4.3e-13
COCLMCBI_00074 6.7e-129
COCLMCBI_00075 8.2e-127 V ABC-type multidrug transport system ATPase component
COCLMCBI_00076 1.8e-60 gntR1 K transcriptional
COCLMCBI_00077 3.4e-190 D NYN domain
COCLMCBI_00078 4.5e-107 rsmP KT Phage shock protein A (IM30), suppresses sigma54-dependent transcription
COCLMCBI_00079 3.3e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
COCLMCBI_00080 6.5e-25 copZ P mercury ion transmembrane transporter activity
COCLMCBI_00081 4.9e-25 copZ P mercury ion transmembrane transporter activity
COCLMCBI_00082 0.0 ctpA 3.6.3.54 P cation transport ATPase
COCLMCBI_00083 9.1e-237 naiP EGP Permeases of the major facilitator superfamily
COCLMCBI_00084 6.4e-263 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COCLMCBI_00085 4.4e-130
COCLMCBI_00086 1.3e-76 rplI J binds to the 23S rRNA
COCLMCBI_00087 3.4e-71 ssb L Single-stranded DNA-binding protein
COCLMCBI_00088 1.2e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
COCLMCBI_00089 5.2e-17
COCLMCBI_00091 9.2e-281 S Integral membrane protein
COCLMCBI_00092 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Membrane carboxypeptidase (Penicillin-binding protein)
COCLMCBI_00093 3.7e-76 uspR K helix_turn_helix multiple antibiotic resistance protein
COCLMCBI_00094 1.2e-169 T Universal stress protein UspA and related nucleotide-binding proteins
COCLMCBI_00095 2.1e-85
COCLMCBI_00096 4.4e-174 yceA S Belongs to the UPF0176 family
COCLMCBI_00097 9.6e-59 K helix_turn_helix, Lux Regulon
COCLMCBI_00098 3.6e-49 T Histidine kinase
COCLMCBI_00101 6.9e-90 mutF V ABC transporter, ATP-binding protein
COCLMCBI_00102 2.1e-277 XK27_07020 S Belongs to the UPF0371 family
COCLMCBI_00103 1.7e-28
COCLMCBI_00104 1.9e-40 XK27_10495 DJ ParE toxin of type II toxin-antitoxin system, parDE
COCLMCBI_00105 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
COCLMCBI_00106 3.5e-249 aceA 4.1.3.1 C Isocitrate lyase
COCLMCBI_00107 5.4e-85 2.3.1.82 J Acetyltransferase (GNAT) domain
COCLMCBI_00108 3.9e-15
COCLMCBI_00109 9.8e-44 S Toxic component of a toxin-antitoxin (TA) module. An RNase
COCLMCBI_00110 3.5e-88 rraA H Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
COCLMCBI_00111 1.1e-139 nei1 3.2.2.23, 4.2.99.18 L Belongs to the FPG family
COCLMCBI_00112 2.5e-35
COCLMCBI_00113 3.2e-77 S Toxic component of a toxin-antitoxin (TA) module. An RNase
COCLMCBI_00114 9.4e-281 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COCLMCBI_00115 4.4e-143 ywaF S Integral membrane protein (intg_mem_TP0381)
COCLMCBI_00116 6.1e-184 EGP Major facilitator Superfamily
COCLMCBI_00117 5.7e-98 yhhW_2 O Belongs to the pirin family
COCLMCBI_00118 5e-129 S Plasmid pRiA4b ORF-3-like protein
COCLMCBI_00119 6.8e-48 S Domain of unknown function (DUF202)
COCLMCBI_00120 3.1e-60 yidH S membrane
COCLMCBI_00121 2.2e-168 adhT C Zinc-binding dehydrogenase
COCLMCBI_00122 2.6e-126
COCLMCBI_00123 1.7e-77 V Glycopeptide antibiotics resistance protein
COCLMCBI_00124 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COCLMCBI_00125 5.7e-291 V HNH endonuclease domain protein
COCLMCBI_00126 4.5e-124
COCLMCBI_00127 4.8e-122 S Psort location
COCLMCBI_00128 3.3e-188 sstT U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COCLMCBI_00129 8e-57 sdpI S Integral membrane protein
COCLMCBI_00130 1.9e-113 hipA_2 2.7.11.1 S TIGRFAM HipA N-terminal domain
COCLMCBI_00131 5.1e-11 K Helix-turn-helix XRE-family like proteins
COCLMCBI_00132 2.8e-274 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COCLMCBI_00133 3.1e-113 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH component II
COCLMCBI_00134 5.5e-189 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COCLMCBI_00135 1.7e-268 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
COCLMCBI_00136 1.2e-230 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COCLMCBI_00137 1.9e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COCLMCBI_00138 1.5e-62 qcrA2 1.8.5.2 P domain protein
COCLMCBI_00139 1.2e-46
COCLMCBI_00140 8.5e-215 V HNH endonuclease domain protein
COCLMCBI_00141 1.9e-62
COCLMCBI_00142 1.1e-46 azlD E branched-chain amino acid
COCLMCBI_00143 1.8e-116 azlC E branched-chain amino acid permease (azaleucine resistance)
COCLMCBI_00144 1.4e-110 K acr, cog1678
COCLMCBI_00145 1.3e-290 cca 2.7.7.19, 2.7.7.72 J tRNA nucleotidyltransferase poly(A) polymerase
COCLMCBI_00146 9.2e-90 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_00147 0.0 NU Tfp pilus assembly protein FimV
COCLMCBI_00148 0.0 murJ S Membrane
COCLMCBI_00149 3.5e-92 sigM K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_00150 2.4e-187 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COCLMCBI_00151 1.6e-41 trxC O Belongs to the thioredoxin family
COCLMCBI_00152 1e-210 cwlM 3.2.1.17, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COCLMCBI_00153 1.7e-126 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COCLMCBI_00154 5.8e-104 S acetyltransferase
COCLMCBI_00155 1.5e-178 parB K Belongs to the ParB family
COCLMCBI_00156 2.6e-164 parA D ATPases involved in chromosome partitioning
COCLMCBI_00157 1.2e-103 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COCLMCBI_00158 6.6e-159 yidC U Preprotein translocase subunit YidC
COCLMCBI_00159 2.2e-52 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COCLMCBI_00160 2.1e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COCLMCBI_00161 2.3e-282 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COCLMCBI_00162 1.3e-218 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COCLMCBI_00163 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COCLMCBI_00164 6.7e-110 S Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives
COCLMCBI_00165 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCLMCBI_00166 2.1e-169 1.1.3.6 S Alpha beta hydrolase
COCLMCBI_00167 0.0 surB D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
COCLMCBI_00168 6.9e-187 P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
COCLMCBI_00169 1.5e-130 U Binding-protein-dependent transport system inner membrane component
COCLMCBI_00170 8.2e-134 tauB P ATPases associated with a variety of cellular activities
COCLMCBI_00171 9.4e-121 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
COCLMCBI_00172 6.5e-122 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
COCLMCBI_00173 1.3e-07
COCLMCBI_00174 4.2e-64
COCLMCBI_00175 3.1e-164
COCLMCBI_00176 1.7e-36
COCLMCBI_00177 1.8e-28
COCLMCBI_00178 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COCLMCBI_00179 2.9e-49 S Transmembrane domain of unknown function (DUF3566)
COCLMCBI_00182 2.8e-193 K Putative ATP-dependent DNA helicase recG C-terminal
COCLMCBI_00183 5.6e-203 CH FAD binding domain
COCLMCBI_00184 4.7e-125 G Polysaccharide deacetylase
COCLMCBI_00185 9.7e-11 S CAAX protease self-immunity
COCLMCBI_00186 6.8e-94 T Histidine kinase
COCLMCBI_00187 2.4e-76 K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COCLMCBI_00188 4.4e-191
COCLMCBI_00190 2e-200 G PFAM glycoside hydrolase family 39
COCLMCBI_00192 3.1e-216 S Secretory lipase
COCLMCBI_00193 5.4e-255 yhgE S YhgE Pip domain protein
COCLMCBI_00194 2.9e-104 P (ABC) transporter
COCLMCBI_00195 1.4e-94 kstR K transcriptional regulator
COCLMCBI_00196 8.6e-14
COCLMCBI_00197 2.6e-164 metF 1.5.1.20 E reductase
COCLMCBI_00198 0.0 metE 2.1.1.14 H Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COCLMCBI_00199 9.3e-108 P ABC transporter permease
COCLMCBI_00200 4.2e-115 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COCLMCBI_00201 1.7e-132 P ABC-type metal ion transport system, periplasmic component surface antigen
COCLMCBI_00203 2.6e-94 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COCLMCBI_00204 5.2e-82 ybhB 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
COCLMCBI_00205 2.9e-249 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C NAD-dependent aldehyde dehydrogenases
COCLMCBI_00206 1.5e-43 crgA D involved in cell division
COCLMCBI_00207 2.2e-308 pknB 2.7.11.1 KLT serine threonine protein kinase
COCLMCBI_00208 4.3e-187 KLT serine threonine protein kinase
COCLMCBI_00209 1.9e-251 pbpA M Cell division protein FtsI penicillin-binding protein 2
COCLMCBI_00210 6.7e-219 rodA D Belongs to the SEDS family
COCLMCBI_00211 4e-214 pstP 3.1.3.16 T serine threonine protein phosphatase
COCLMCBI_00212 2.6e-58 fhaB T FHA domain
COCLMCBI_00213 6.5e-148 fhaA T FHA domain
COCLMCBI_00215 4.4e-35 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00216 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_00217 9e-50 L Transposase and inactivated derivatives
COCLMCBI_00218 2.6e-38 S MbtH-like protein
COCLMCBI_00219 0.0 V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_00220 7.4e-303 V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_00221 8.5e-273 1.14.13.195, 1.14.13.196 Q L-lysine 6-monooxygenase (NADPH-requiring)
COCLMCBI_00222 1.5e-40 Q Non-ribosomal peptide synthetase modules and related proteins
COCLMCBI_00223 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
COCLMCBI_00224 1.7e-190 fes P alpha/beta hydrolase fold
COCLMCBI_00225 2.2e-156 arnA 1.1.1.305, 2.1.2.13, 2.1.2.9 J Formyl transferase, C-terminal domain
COCLMCBI_00226 1.6e-188 P ABC-type Fe3 -hydroxamate transport system, periplasmic component
COCLMCBI_00227 1.5e-112 dedA S Membrane-associated protein
COCLMCBI_00228 1.5e-141 3.6.3.34 HP ATPases associated with a variety of cellular activities
COCLMCBI_00229 3.2e-179 fepG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00230 4.2e-190 fepD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00231 1.3e-61 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COCLMCBI_00232 2.5e-84 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COCLMCBI_00233 3.9e-61 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COCLMCBI_00234 1.9e-78 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COCLMCBI_00235 3.2e-15 rpmD J Ribosomal protein L30
COCLMCBI_00237 9e-50 L Transposase and inactivated derivatives
COCLMCBI_00238 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_00239 6.3e-247 L Transposase and inactivated derivatives
COCLMCBI_00241 2.9e-56 repA KT Replicase family
COCLMCBI_00242 1.1e-214 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00243 2.9e-86
COCLMCBI_00244 1e-125 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COCLMCBI_00245 9.3e-196 tcsS4 2.7.13.3 T Histidine kinase
COCLMCBI_00246 3.7e-31 P Heavy-metal-associated domain
COCLMCBI_00247 0.0 copB 3.6.3.4 P cation transport ATPase
COCLMCBI_00248 4.4e-107 glpF U water channel activity
COCLMCBI_00249 1.6e-76 S Carboxymuconolactone decarboxylase family
COCLMCBI_00250 6.6e-103 1.1.1.100, 1.1.1.401 I Belongs to the short-chain dehydrogenases reductases (SDR) family
COCLMCBI_00251 0.0 glsA 3.5.1.2 E Belongs to the glutaminase family
COCLMCBI_00252 1.4e-38
COCLMCBI_00253 1.7e-34 K Helix-turn-helix XRE-family like proteins
COCLMCBI_00254 5.6e-45 K Transcriptional regulator
COCLMCBI_00255 3.4e-217 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain protein
COCLMCBI_00256 3.8e-96
COCLMCBI_00257 2.4e-278 gabD2 1.2.1.16, 1.2.1.20, 1.2.1.79, 1.2.99.10 C Belongs to the aldehyde dehydrogenase family
COCLMCBI_00258 6.4e-257 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
COCLMCBI_00259 5.1e-108 V Beta-lactamase
COCLMCBI_00260 2.7e-271 amn 3.2.2.4 F Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations
COCLMCBI_00261 6.3e-171 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
COCLMCBI_00262 1.4e-208 GT87 S Glycosyltransferase family 87
COCLMCBI_00263 1.7e-64 gca S Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COCLMCBI_00264 2.8e-183 K Transcriptional regulator sugar kinase
COCLMCBI_00265 1.5e-133 cobB K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COCLMCBI_00266 1.4e-309 S protein conserved in bacteria
COCLMCBI_00267 3.3e-162 abrB S Ammonia monooxygenase
COCLMCBI_00268 1.7e-118 S membrane transporter protein
COCLMCBI_00270 1.7e-268 lysI E L-lysine transport protein
COCLMCBI_00271 0.0 hrpB 3.6.4.13 L ATP-dependent helicase
COCLMCBI_00272 3.3e-125
COCLMCBI_00273 5.3e-104 maa 2.3.1.79 S acetyltransferase, isoleucine patch superfamily
COCLMCBI_00274 2.3e-122 yusR L Belongs to the short-chain dehydrogenases reductases (SDR) family
COCLMCBI_00275 3.7e-88 rhtC E threonine efflux protein
COCLMCBI_00276 2.6e-145 dacB 3.4.16.4 M Multidrug Resistance protein
COCLMCBI_00277 1.3e-48 ybjQ S Belongs to the UPF0145 family
COCLMCBI_00278 1.1e-32 yaaA S S4 domain protein
COCLMCBI_00279 1.8e-140 cfp30B S enzyme related to lactoylglutathione lyase
COCLMCBI_00280 1.3e-125 dacB 3.4.16.4 M Multidrug Resistance protein
COCLMCBI_00281 6.2e-202 L HNH endonuclease domain protein
COCLMCBI_00282 3e-174 I esterase lipase
COCLMCBI_00283 0.0 pepO 3.4.24.71 O Metalloendopeptidase
COCLMCBI_00284 0.0 embC M Mycobacterial cell wall arabinan synthesis protein
COCLMCBI_00285 0.0 aftA 2.4.2.46 GT85 S Arabinofuranosyltransferase N terminal
COCLMCBI_00286 1e-134 dprE2 1.1.1.333 S Short chain dehydrogenase
COCLMCBI_00287 3.7e-276 dprE1 1.1.98.3 C FAD FMN-containing dehydrogenases
COCLMCBI_00288 1.2e-29
COCLMCBI_00289 7.4e-147
COCLMCBI_00290 2.6e-77 S membrane
COCLMCBI_00291 3.1e-167 glfT1 2.4.1.287 GT2 S Glycosyltransferase, group 2 family protein
COCLMCBI_00292 1.3e-143
COCLMCBI_00293 2.3e-145 rfbE 3.6.3.38 GM ABC-type polysaccharide polyol phosphate transport system ATPase component
COCLMCBI_00294 3.7e-171 rfbD GM ABC-type polysaccharide polyol phosphate export systems permease component
COCLMCBI_00295 1.6e-211 csd 2.8.1.7 E Selenocysteine lyase
COCLMCBI_00297 1e-58 yvlD S membrane
COCLMCBI_00298 2.5e-71
COCLMCBI_00299 6.6e-182 pat 2.6.1.9 E May catalyze the transamination reaction in phenylalanine biosynthesis
COCLMCBI_00302 1.2e-199 mgtE P Acts as a magnesium transporter
COCLMCBI_00304 8.7e-174 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
COCLMCBI_00305 7.1e-78 S tRNA adenosine
COCLMCBI_00306 1.1e-75 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COCLMCBI_00307 1.6e-15 S Belongs to the UPF0337 (CsbD) family
COCLMCBI_00309 0.0 mmpL2 S drug exporters of the RND superfamily
COCLMCBI_00310 5.4e-231 tgt 2.4.2.29 J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COCLMCBI_00311 3.5e-17 VY92_11025 D Antitoxin component of a toxin-antitoxin (TA) module
COCLMCBI_00312 3.3e-34 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
COCLMCBI_00313 1.7e-114 yhhQ S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COCLMCBI_00314 1.8e-162 gluQ 6.1.1.17 J Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
COCLMCBI_00315 1.4e-133 6.2.1.3 H Aldolase/RraA
COCLMCBI_00317 1e-240 aspT EK HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COCLMCBI_00318 7.9e-83 S Suppressor of fused protein (SUFU)
COCLMCBI_00319 8.8e-108 T Response regulator receiver domain protein
COCLMCBI_00320 8e-112 T Histidine kinase
COCLMCBI_00321 1.3e-114 V ABC transporter, ATP-binding protein
COCLMCBI_00322 1.8e-211 V Efflux ABC transporter, permease protein
COCLMCBI_00323 9.1e-283 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COCLMCBI_00324 2.5e-43 ybaB S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COCLMCBI_00325 4.4e-115 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COCLMCBI_00326 8.3e-115 cobQ S glutamine amidotransferase
COCLMCBI_00327 4e-213 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M UDP-N-acetylmuramyl tripeptide synthase
COCLMCBI_00328 7.2e-173 dnaQ 2.7.7.7 L DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
COCLMCBI_00329 3e-63
COCLMCBI_00330 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COCLMCBI_00331 7.9e-120 EG Permeases of the drug metabolite transporter (DMT) superfamily
COCLMCBI_00332 5.1e-146 fmdA 3.5.1.4 C formamidase
COCLMCBI_00333 1.3e-219 ask 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
COCLMCBI_00334 8.3e-185 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COCLMCBI_00335 3.4e-92 sigC K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_00336 0.0 katA 1.11.1.6 C Catalase
COCLMCBI_00337 1.7e-62 mnhG P Multisubunit Na H antiporter MnhG subunit
COCLMCBI_00338 2.2e-36 mnhF
COCLMCBI_00339 3.3e-65 mrpE P multisubunit Na H antiporter MnhE subunit
COCLMCBI_00340 6.2e-277 mnhD CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit
COCLMCBI_00341 1.6e-59 phaC 1.6.5.3 P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
COCLMCBI_00342 0.0 mrpA 1.6.5.3 CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit
COCLMCBI_00343 1.4e-167 yhgE S membrane
COCLMCBI_00345 0.0 phoA 3.1.3.1, 3.1.3.39 P Belongs to the alkaline phosphatase family
COCLMCBI_00347 9.1e-164 ykuE S Ser Thr phosphatase family protein
COCLMCBI_00348 2.3e-67 yqeY S Yqey-like protein
COCLMCBI_00349 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Membrane carboxypeptidase (Penicillin-binding protein)
COCLMCBI_00350 4.1e-62 whiB4 K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COCLMCBI_00351 3.5e-23 S Domain of unknown function (DUF4177)
COCLMCBI_00352 5.1e-70 yabJ J translation initiation inhibitor, yjgF family
COCLMCBI_00353 8.2e-151 MA20_07390 3.1.2.6 S Zn-dependent hydrolases including glyoxylases
COCLMCBI_00354 1.1e-121 glxR K cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
COCLMCBI_00355 1.2e-149 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COCLMCBI_00356 4.7e-79 resA_1 CO Thiol-disulfide isomerase and thioredoxins
COCLMCBI_00357 2.1e-126 nudL L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_00358 1e-162 cvpA O Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
COCLMCBI_00359 2.5e-156 ephE S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COCLMCBI_00360 1.7e-83 S Putative Actinobacterial Holin-X, holin superfamily III
COCLMCBI_00361 2.1e-132 ssgB E phosphoserine phosphatase
COCLMCBI_00362 1.2e-208 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00363 1e-145 cpaE D bacterial-type flagellum organization
COCLMCBI_00364 2.3e-196 cpaF U Flp pilus assembly protein, ATPase CpaF
COCLMCBI_00365 2.4e-91 U Flp pilus assembly protein TadB
COCLMCBI_00366 8.1e-80 gspF NU Type II secretion system
COCLMCBI_00367 1.8e-34 S Protein of unknown function (DUF4244)
COCLMCBI_00368 1.3e-40
COCLMCBI_00369 8.2e-28 S TIGRFAM helicase secretion neighborhood TadE-like protein
COCLMCBI_00370 0.0 yprA L Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
COCLMCBI_00371 2.3e-30 cspA K Cold shock proteins
COCLMCBI_00372 3.2e-110 S SNARE associated Golgi protein
COCLMCBI_00373 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COCLMCBI_00374 2.2e-266 cya 4.6.1.1 T Adenylate cyclase, family 3 (some proteins contain HAMP domain)
COCLMCBI_00375 6.7e-218 holB 2.7.7.7 L DNA polymerase III
COCLMCBI_00377 9e-47 sugE P Multidrug resistance protein
COCLMCBI_00378 1.7e-32 sugE P Multidrug resistance protein
COCLMCBI_00379 6.6e-44 guaD 3.5.4.3, 3.5.4.33 FJ Cytidine and deoxycytidylate deaminase zinc-binding region
COCLMCBI_00380 1.1e-25 Q protein disulfide oxidoreductase activity
COCLMCBI_00381 5.3e-29 K helix_turn_helix multiple antibiotic resistance protein
COCLMCBI_00382 1e-83 Q Domain of unknown function (DUF4442)
COCLMCBI_00383 1.4e-197 fadD9 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_00384 2.7e-157 E GDSL-like Lipase/Acylhydrolase family
COCLMCBI_00385 3.7e-194 adhC 1.1.1.306 C Alcohol dehydrogenase GroES-like domain
COCLMCBI_00386 7.9e-114 3.1.2.6 S Zn-dependent hydrolases including glyoxylases
COCLMCBI_00387 7.1e-135 bdbD O DSBA-like thioredoxin domain
COCLMCBI_00388 2.1e-59 S Uncharacterized conserved protein (DUF2304)
COCLMCBI_00389 3.5e-126 M Glycosyltransferases involved in cell wall biogenesis
COCLMCBI_00390 3.2e-134 amsE 2.4.1.303 GT2 M involved in cell wall biogenesis
COCLMCBI_00391 1.3e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COCLMCBI_00392 3.7e-261 V endonuclease
COCLMCBI_00393 5.7e-250 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COCLMCBI_00394 8.6e-227 EGP Major facilitator Superfamily
COCLMCBI_00395 1.2e-52 K helix_turn_helix, Arsenical Resistance Operon Repressor
COCLMCBI_00396 6.5e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COCLMCBI_00397 5.4e-199 S polysaccharide biosynthetic process
COCLMCBI_00398 3.6e-238 1.11.1.19 P Iron-dependent peroxidase
COCLMCBI_00399 1.7e-76 VY92_09940 S protein conserved in bacteria
COCLMCBI_00400 0.0 f1pep1 3.4.21.26 E Serine proteases of the peptidase family S9A
COCLMCBI_00401 7.5e-195 cmtA S esterase
COCLMCBI_00403 1.9e-211 cmtA S esterase
COCLMCBI_00404 4.1e-262 lpd 1.8.1.4 C Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes
COCLMCBI_00405 2e-82 S Domain of unknown function (DUF4352)
COCLMCBI_00406 1.2e-80 S Polyketide cyclase / dehydrase and lipid transport
COCLMCBI_00407 2.6e-135 sdhC C succinate dehydrogenase
COCLMCBI_00408 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
COCLMCBI_00409 1.3e-142 sdhB 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase fumarate reductase
COCLMCBI_00410 4.7e-61
COCLMCBI_00411 8.4e-43 L Transposase and inactivated derivatives
COCLMCBI_00412 2.5e-144 insK L Transposase and inactivated derivatives
COCLMCBI_00413 1.5e-239 S membrane
COCLMCBI_00414 9.8e-88
COCLMCBI_00415 2.3e-48 S Protein of unknown function (DUF2516)
COCLMCBI_00416 1.3e-68 deoC 4.1.2.4 F deoxyribose-phosphate aldolase
COCLMCBI_00417 5.4e-118 S Protein of unknown function (DUF2993)
COCLMCBI_00418 1e-153 J protein-(glutamine-N5) methyltransferase activity
COCLMCBI_00419 2.6e-83 S Protein of unknown function (DUF2505)
COCLMCBI_00420 7.8e-186 murB 1.3.1.98 M Cell wall formation
COCLMCBI_00421 0.0 fadD7 6.2.1.3 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_00422 3.4e-181 D AAA domain
COCLMCBI_00423 1.8e-221 mshA 2.4.1.250 M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway
COCLMCBI_00424 2e-188
COCLMCBI_00425 1e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COCLMCBI_00426 3.9e-202 senX3 2.7.13.3 T Histidine kinase
COCLMCBI_00427 6.6e-125 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COCLMCBI_00428 1.7e-167
COCLMCBI_00429 1e-165 ppx 3.6.1.11, 3.6.1.40 FP Exopolyphosphatase
COCLMCBI_00430 7.1e-65
COCLMCBI_00431 1.5e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COCLMCBI_00432 1.8e-27 xis K DNA binding domain, excisionase family
COCLMCBI_00434 3.5e-132 namA C NADH flavin oxidoreductase NADH oxidase
COCLMCBI_00435 6.7e-162 serB1 E phosphoserine phosphatase
COCLMCBI_00436 1.7e-36 O Thiol-disulfide isomerase and thioredoxins
COCLMCBI_00437 1.1e-219 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
COCLMCBI_00438 1.6e-147 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
COCLMCBI_00439 8.4e-291 hemD 1.3.1.76, 2.1.1.107, 4.2.1.75, 4.99.1.4 H Uroporphyrinogen-III synthase
COCLMCBI_00440 1e-164 hemB 4.2.1.24 H Belongs to the ALAD family
COCLMCBI_00441 7.8e-55
COCLMCBI_00442 7.8e-77
COCLMCBI_00443 0.0 ccoI 3.6.3.4, 3.6.3.54 P cation transport ATPase
COCLMCBI_00444 3.7e-188 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
COCLMCBI_00445 4.5e-261 hemG 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
COCLMCBI_00446 1.6e-137 S Pfam SNARE associated Golgi protein
COCLMCBI_00447 3.4e-139 S UPF0126 domain
COCLMCBI_00448 3.4e-148 galM 5.1.3.3 G Aldose 1-epimerase
COCLMCBI_00449 2.8e-196 L HNH endonuclease domain protein
COCLMCBI_00450 5.6e-234 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
COCLMCBI_00451 1.5e-112 3.1.3.3, 3.1.3.73 G phosphoglycerate mutase
COCLMCBI_00452 2.6e-98 resA CO Thiol-disulfide isomerase and thioredoxins
COCLMCBI_00453 5.1e-134 ccdA O cytochrome c biogenesis protein
COCLMCBI_00454 3.8e-309 resB O ResB protein required for cytochrome c biosynthesis
COCLMCBI_00455 8.3e-185 ccsA O ABC-type transport system involved in cytochrome c biogenesis permease component
COCLMCBI_00456 1.4e-37 K Helix-turn-helix domain
COCLMCBI_00457 9.9e-26
COCLMCBI_00458 6.1e-43 S Protein of unknown function (DUF4229)
COCLMCBI_00459 1.9e-151 mdcF S permeases
COCLMCBI_00460 1.6e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
COCLMCBI_00461 6.6e-167 M transferase activity, transferring glycosyl groups
COCLMCBI_00462 7.7e-208 menE 6.2.1.26 IQ O-succinylbenzoic acid--CoA ligase
COCLMCBI_00463 1.9e-185 T Histidine kinase
COCLMCBI_00464 2.1e-112 K Response regulator receiver domain protein
COCLMCBI_00465 2e-115 V ABC transporter, ATP-binding protein
COCLMCBI_00466 1.5e-240 mutE S ABC-2 family transporter protein
COCLMCBI_00467 1e-173 menB 4.1.3.36 H Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily
COCLMCBI_00468 1.5e-08 S FeoA domain
COCLMCBI_00469 4.4e-270 feoB P transporter of a GTP-driven Fe(2 ) uptake system
COCLMCBI_00470 6.6e-23 S FeoC like transcriptional regulator
COCLMCBI_00472 7.1e-176 menC 4.2.1.113, 5.1.1.20, 5.1.1.3 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COCLMCBI_00473 1.1e-268 sdcS P Transporter, DASS family
COCLMCBI_00474 2e-48
COCLMCBI_00475 7.1e-287 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
COCLMCBI_00476 2.5e-69
COCLMCBI_00477 6e-208 mgtA GT4 M Glycosyltransferase, group 1 family protein
COCLMCBI_00478 7.1e-124 ubiE 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COCLMCBI_00479 8.9e-221 menJ 1.3.99.38 C Dehydrogenases (flavoproteins)
COCLMCBI_00480 2.3e-171 hepS 2.5.1.30 H Belongs to the FPP GGPP synthase family
COCLMCBI_00482 7.2e-206 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00483 8.1e-224 S Esterase-like activity of phytase
COCLMCBI_00487 1.3e-46 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COCLMCBI_00488 4.5e-122 nusG K Participates in transcription elongation, termination and antitermination
COCLMCBI_00489 6.1e-73 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COCLMCBI_00490 3.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COCLMCBI_00491 3.6e-135 insK L Transposase and inactivated derivatives
COCLMCBI_00492 7e-58 L Helix-turn-helix domain
COCLMCBI_00493 3.9e-24 V Beta-lactamase class C and other penicillin binding proteins
COCLMCBI_00494 3.7e-72 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COCLMCBI_00495 1.3e-40 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COCLMCBI_00496 4.5e-156 S Protein of unknown function (DUF3068)
COCLMCBI_00497 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCLMCBI_00498 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCLMCBI_00499 7e-79 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COCLMCBI_00500 3.5e-110 casE S CRISPR_assoc
COCLMCBI_00501 1.5e-111 casD S CRISPR-associated protein (Cas_Cas5)
COCLMCBI_00502 2.4e-172 casC L CT1975-like protein
COCLMCBI_00503 1.6e-93 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
COCLMCBI_00504 4.8e-222 cas3 L CRISPR-associated protein Cse1 (CRISPR_cse1)
COCLMCBI_00505 0.0 cas3 L CRISPR-associated
COCLMCBI_00506 2.3e-60 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COCLMCBI_00507 5.1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COCLMCBI_00508 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COCLMCBI_00509 2.2e-221 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COCLMCBI_00510 7.7e-102
COCLMCBI_00511 2.2e-86
COCLMCBI_00512 6.5e-92 S Protein conserved in bacteria
COCLMCBI_00513 6.1e-79 S Asp23 family, cell envelope-related function
COCLMCBI_00514 2.1e-15
COCLMCBI_00515 1.1e-08 S Protein conserved in bacteria
COCLMCBI_00516 1.2e-86 S protein conserved in bacteria
COCLMCBI_00517 5.7e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COCLMCBI_00518 2.9e-106 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COCLMCBI_00519 3.6e-117 rplD J Forms part of the polypeptide exit tunnel
COCLMCBI_00520 5.3e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COCLMCBI_00521 7e-158 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COCLMCBI_00522 2.8e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COCLMCBI_00523 3.6e-55 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COCLMCBI_00524 4.1e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COCLMCBI_00525 8.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COCLMCBI_00526 6.7e-34 rpmC J Belongs to the universal ribosomal protein uL29 family
COCLMCBI_00527 1.2e-49 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COCLMCBI_00528 1.6e-62 scrK 2.7.1.20, 2.7.1.4 G pfkB family carbohydrate kinase
COCLMCBI_00529 5.1e-287 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 3.5.99.2 H Phosphomethylpyrimidine kinase
COCLMCBI_00530 9e-271 PPA1638 S 50S ribosome-binding GTPase
COCLMCBI_00531 0.0 S ABC transporter
COCLMCBI_00532 4.8e-140 fnt P Formate nitrite
COCLMCBI_00533 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COCLMCBI_00534 3e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COCLMCBI_00535 2.3e-107 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COCLMCBI_00536 6.9e-147 P Siderophore-interacting protein
COCLMCBI_00537 1.5e-169 fecS P ABC-type Fe3 -hydroxamate transport system, periplasmic component
COCLMCBI_00538 4.9e-129 fecB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00539 1.3e-174 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00540 8.6e-145 3.6.3.34 HP transport systems ATPase components
COCLMCBI_00541 0.0 alcC Q IucA / IucC family
COCLMCBI_00542 7.4e-194 alcA 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
COCLMCBI_00543 1.9e-174 ddc 4.1.1.86 E Pyridoxal-dependent decarboxylase conserved domain
COCLMCBI_00544 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COCLMCBI_00545 3e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COCLMCBI_00546 2.3e-107 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COCLMCBI_00547 2.2e-208 3.1.3.1 S Esterase-like activity of phytase
COCLMCBI_00548 8.2e-104
COCLMCBI_00550 9.2e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COCLMCBI_00551 9.9e-80 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COCLMCBI_00552 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COCLMCBI_00553 5.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COCLMCBI_00554 2.8e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COCLMCBI_00555 4.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COCLMCBI_00556 7e-26 rpmD J Ribosomal protein L30
COCLMCBI_00557 1.5e-95 rplO J binds to the 23S rRNA
COCLMCBI_00558 1.9e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COCLMCBI_00559 6.1e-94 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COCLMCBI_00560 1.4e-139 map 3.4.11.18 E Methionine aminopeptidase
COCLMCBI_00562 8.6e-110 MA20_01915 S protein conserved in bacteria
COCLMCBI_00563 8.3e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COCLMCBI_00564 1.7e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COCLMCBI_00565 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COCLMCBI_00566 2.2e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COCLMCBI_00567 4e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COCLMCBI_00568 2.1e-61 rplQ J Ribosomal protein L17
COCLMCBI_00569 9.1e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COCLMCBI_00570 0.0 S Psort location CytoplasmicMembrane, score
COCLMCBI_00571 2.7e-220 eccB S type VII secretion protein EccB
COCLMCBI_00574 4.7e-187 mycP4 M Belongs to the peptidase S8 family
COCLMCBI_00575 1.3e-179 eccD
COCLMCBI_00576 0.0 eccCa D DNA segregation ATPase FtsK SpoIIIE and related proteins
COCLMCBI_00577 2.7e-130
COCLMCBI_00578 5.4e-39 esxU S Belongs to the WXG100 family
COCLMCBI_00579 7.3e-38 esxT S Belongs to the WXG100 family
COCLMCBI_00580 9.1e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COCLMCBI_00581 9.8e-95 rpsI J Belongs to the universal ribosomal protein uS9 family
COCLMCBI_00582 1.4e-237 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COCLMCBI_00583 2.5e-08
COCLMCBI_00585 1.1e-34
COCLMCBI_00586 7.9e-157 3.1.1.45 Q Dienelactone hydrolase
COCLMCBI_00587 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COCLMCBI_00588 4.8e-109 irp5
COCLMCBI_00589 2.2e-191 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COCLMCBI_00590 5.2e-81 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
COCLMCBI_00591 6.9e-74
COCLMCBI_00592 2.8e-104 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COCLMCBI_00593 1.7e-79 rimI 2.3.1.128, 2.3.1.234 K Acetyltransferase
COCLMCBI_00594 3.4e-181 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COCLMCBI_00595 5.2e-75
COCLMCBI_00596 4.2e-62 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COCLMCBI_00597 1.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COCLMCBI_00598 2.5e-55 whiB3 K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COCLMCBI_00599 1.4e-99 sigD K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_00600 8.2e-52
COCLMCBI_00601 9.6e-64 S Family of unknown function (DUF5319)
COCLMCBI_00602 2e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
COCLMCBI_00603 1.2e-206 guaB 1.1.1.205 F IMP dehydrogenase GMP reductase
COCLMCBI_00604 3.2e-135 sitA P Belongs to the bacterial solute-binding protein 9 family
COCLMCBI_00605 3.5e-111 sitB P transport system, ATP-binding protein
COCLMCBI_00606 1.9e-108 mntB P ABC 3 transport family
COCLMCBI_00607 1.4e-90 sirR K Mn-dependent transcriptional regulator
COCLMCBI_00608 6.7e-285 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COCLMCBI_00609 2.9e-146 pspC KT stress-responsive transcriptional regulator
COCLMCBI_00610 5.1e-189 tcsS3 T Signal transduction histidine kinase
COCLMCBI_00611 3.2e-113 degU K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COCLMCBI_00612 6.9e-259 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
COCLMCBI_00613 9.2e-109 imuA S Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
COCLMCBI_00614 9.7e-278 dinB_2 L DNA polymerase involved in DNA repair
COCLMCBI_00615 2e-169 O protein conserved in bacteria containing thioredoxin-like domain
COCLMCBI_00616 1.2e-115 metI P ABC-type metal ion transport system permease component
COCLMCBI_00617 1.3e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COCLMCBI_00618 2e-150 metQ P ABC-type metal ion transport system, periplasmic component surface antigen
COCLMCBI_00619 0.0 dnaE2 2.7.7.6, 2.7.7.7 L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase
COCLMCBI_00620 1.3e-165 C Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
COCLMCBI_00621 2.1e-94 S Bacterial PH domain
COCLMCBI_00622 1.2e-239 S membrane
COCLMCBI_00623 4.8e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COCLMCBI_00624 1.7e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COCLMCBI_00625 1.5e-34 S Protein of unknown function (DUF3017)
COCLMCBI_00626 3.5e-90 Q Methyltransferase domain
COCLMCBI_00627 1e-24 K SpoVT / AbrB like domain
COCLMCBI_00628 3e-29 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
COCLMCBI_00629 2.4e-225 metXA 2.3.1.31 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COCLMCBI_00630 1.9e-242 metY 2.5.1.49 E O-acetylhomoserine
COCLMCBI_00631 6.3e-256
COCLMCBI_00632 0.0 mtsE S VWA domain containing CoxE-like protein
COCLMCBI_00633 6.3e-199 S ATPase family associated with various cellular activities (AAA)
COCLMCBI_00634 0.0
COCLMCBI_00635 0.0
COCLMCBI_00636 2e-158 C Domain of unknown function (DUF4132)
COCLMCBI_00637 1.7e-07 S Protein of unknown function (DUF2510)
COCLMCBI_00638 0.0 icd 1.1.1.42 C Isocitrate dehydrogenase
COCLMCBI_00639 6.6e-170 exoA 3.1.11.2 L exodeoxyribonuclease III
COCLMCBI_00640 5.4e-75 S protein with SCP PR1 domains
COCLMCBI_00641 9.6e-176 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COCLMCBI_00642 5.5e-24
COCLMCBI_00643 5.5e-95
COCLMCBI_00644 5.6e-130 V (ABC) transporter
COCLMCBI_00645 1.5e-56 K transcriptional
COCLMCBI_00646 1.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
COCLMCBI_00647 2e-152 yhjD S membrane
COCLMCBI_00648 2.5e-202 dac 3.4.16.4 M Belongs to the peptidase S11 family
COCLMCBI_00649 5.4e-101 S membrane
COCLMCBI_00650 2.9e-216
COCLMCBI_00651 8.3e-113 M NlpC P60 family protein
COCLMCBI_00653 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COCLMCBI_00654 9.6e-68 K Helix-turn-helix XRE-family like proteins
COCLMCBI_00655 4.6e-227 amiA S amidohydrolase
COCLMCBI_00656 2.3e-254 lpdA 1.8.1.4 C Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COCLMCBI_00657 4.2e-26 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
COCLMCBI_00658 6.7e-204 S ATPase (AAA superfamily)
COCLMCBI_00659 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
COCLMCBI_00660 1.7e-97 chrA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COCLMCBI_00661 2.4e-172 chrS T Histidine kinase
COCLMCBI_00662 8.6e-139 hrtB V ABC-type antimicrobial peptide transport system, permease component
COCLMCBI_00663 1.6e-109 hrtA V ABC-type antimicrobial peptide transport system, ATPase component
COCLMCBI_00664 9.4e-83 K Acetyltransferase
COCLMCBI_00665 1.8e-293 bccA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Acetyl propionyl-CoA carboxylase alpha subunit
COCLMCBI_00666 1.6e-173 sseA 2.8.1.1, 2.8.1.2 P Sulfurtransferase
COCLMCBI_00667 1.3e-204 HJ ligase activity
COCLMCBI_00668 2.5e-29 K Domain of unknown function (DUF4282)
COCLMCBI_00669 3.2e-68 S Protein of unknown function (DUF3151)
COCLMCBI_00670 9.9e-36 S Protein of unknown function (DUF3253)
COCLMCBI_00671 1.9e-30 S membrane
COCLMCBI_00672 3.6e-94 maf 1.1.1.25, 2.1.1.190 D Maf-like protein
COCLMCBI_00673 2e-11 S Acyl-CoA carboxylase epsilon subunit
COCLMCBI_00674 6.1e-269 accD2 2.1.3.15, 6.4.1.3 I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COCLMCBI_00675 7.5e-60
COCLMCBI_00676 3.1e-90 K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_00678 2.9e-292 hscA O Belongs to the heat shock protein 70 family
COCLMCBI_00679 1.9e-203
COCLMCBI_00680 8.3e-305 S Dynamin family
COCLMCBI_00681 1.3e-268 S Dynamin family
COCLMCBI_00682 0.0 2.7.7.7 L DNA polymerase III, epsilon subunit
COCLMCBI_00684 1.4e-161 S Type I phosphodiesterase / nucleotide pyrophosphatase
COCLMCBI_00685 2.6e-203 3.6.3.30 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
COCLMCBI_00686 2.7e-136 P Binding-protein-dependent transport system inner membrane component
COCLMCBI_00687 2.5e-167 P Binding-protein-dependent transport systems inner membrane component
COCLMCBI_00688 3.1e-193 P Bacterial extracellular solute-binding protein
COCLMCBI_00689 4.2e-97 pgmB 3.1.3.18, 5.4.2.6 S HAD hydrolase, family IA, variant 3
COCLMCBI_00690 1.9e-107 2.7.7.7 L DNA polymerase III, epsilon subunit
COCLMCBI_00691 3.9e-245 yfjM K Protein of unknown function DUF262
COCLMCBI_00692 0.0 3.6.4.13 L Restriction endonuclease
COCLMCBI_00695 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_00696 9e-50 L Transposase and inactivated derivatives
COCLMCBI_00697 3.2e-115 L Transposase and inactivated derivatives
COCLMCBI_00700 2.5e-247
COCLMCBI_00701 4e-43 arsR K transcriptional
COCLMCBI_00702 2.5e-190 arsB P Arsenite efflux pump ACR3 and related permeases
COCLMCBI_00703 4.3e-71 arsC 1.20.4.1, 2.8.4.2 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCLMCBI_00704 8.6e-76 S Protein of unknown function, DUF488
COCLMCBI_00705 2.7e-138 birA 2.7.1.33, 6.3.4.15 H Biotin-(Acetyl-CoA carboxylase) ligase
COCLMCBI_00706 3.9e-67 S Bacterial PH domain
COCLMCBI_00707 2e-138 budA 4.1.1.5 Q Belongs to the alpha-acetolactate decarboxylase family
COCLMCBI_00708 3.5e-208 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COCLMCBI_00709 1.4e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COCLMCBI_00710 6.7e-76 sanA S DUF218 domain
COCLMCBI_00711 1.1e-124 IQ COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
COCLMCBI_00712 1.3e-256 lytR2 K transcriptional
COCLMCBI_00713 3.4e-155 wbbL 2.4.1.289 S Glycosyltransferases
COCLMCBI_00714 4.7e-170 manC 2.7.7.13, 5.4.2.8 JM Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits
COCLMCBI_00715 5.4e-51 whiB2 K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COCLMCBI_00716 8.2e-61 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
COCLMCBI_00717 5e-69 S Protein of unknown function (DUF3499)
COCLMCBI_00718 1.3e-35 VY92_11025 D Antitoxin component of a toxin-antitoxin (TA) module
COCLMCBI_00719 1.7e-67 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
COCLMCBI_00720 2.1e-247 manB 5.4.2.2, 5.4.2.8 G the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells
COCLMCBI_00721 4.9e-158 5.3.1.8, 5.3.1.9 K Transcriptional regulator
COCLMCBI_00722 3.2e-199 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G isomerase
COCLMCBI_00724 2.7e-53
COCLMCBI_00725 1.6e-274 ahcY 3.3.1.1 H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
COCLMCBI_00726 9.7e-64 tmk 2.1.1.45, 2.7.4.9, 4.1.1.19 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COCLMCBI_00727 9.8e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COCLMCBI_00728 1.5e-270 mtrB 2.7.13.3 T Histidine kinase
COCLMCBI_00729 2.7e-308 lpqB S Lipoprotein LpqB
COCLMCBI_00730 9.1e-102 ctsW S phosphoribosyltransferase
COCLMCBI_00731 4.9e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COCLMCBI_00732 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCLMCBI_00733 7e-57
COCLMCBI_00734 1.6e-70 3.1.3.10, 3.1.3.102, 3.1.3.104 S hydrolase
COCLMCBI_00735 1.1e-81
COCLMCBI_00736 6.3e-247 L Transposase and inactivated derivatives
COCLMCBI_00737 9.6e-184 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COCLMCBI_00738 2.8e-230 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COCLMCBI_00739 1.3e-93 yedK S Belongs to the SOS response-associated peptidase family
COCLMCBI_00740 1e-73 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COCLMCBI_00741 6.1e-100 sigH K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_00742 6.6e-15
COCLMCBI_00743 6.7e-43 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
COCLMCBI_00744 2.4e-73
COCLMCBI_00745 2.3e-210 S ErfK ybiS ycfS ynhG family protein
COCLMCBI_00746 9.9e-215 deaD 3.6.4.13 L Belongs to the DEAD box helicase family
COCLMCBI_00747 3.8e-18 S Protein of unknown function (DUF3107)
COCLMCBI_00748 2.7e-160 M Protein of unknown function (DUF3152)
COCLMCBI_00749 2.1e-126 S Aminoglycoside phosphotransferase
COCLMCBI_00750 0.0 uvrD 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
COCLMCBI_00751 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
COCLMCBI_00752 3.5e-197 kch 3.6.1.22 P Kef-type K transport systems
COCLMCBI_00753 0.0 uvrD2 3.6.4.12 L DNA helicase
COCLMCBI_00754 9e-50 L Transposase and inactivated derivatives
COCLMCBI_00755 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_00756 4.7e-106
COCLMCBI_00757 1.2e-83 S Metal-dependent hydrolase
COCLMCBI_00758 8.7e-228 S hydrolase
COCLMCBI_00759 5.5e-179 lon T Belongs to the peptidase S16 family
COCLMCBI_00760 6.4e-72
COCLMCBI_00761 4.9e-85
COCLMCBI_00762 0.0 S UPF0182 protein
COCLMCBI_00764 3.9e-187 S Domain of unknown function (DUF4192)
COCLMCBI_00765 4.9e-19
COCLMCBI_00766 1.9e-66 L single-stranded DNA binding
COCLMCBI_00767 6e-123 sirR K Mn-dependent transcriptional regulator
COCLMCBI_00768 3.7e-75 nrdI F Probably involved in ribonucleotide reductase function
COCLMCBI_00769 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCLMCBI_00770 1.7e-190 nrdF 1.17.4.1 F reductase beta subunit
COCLMCBI_00771 5.1e-107 yieF S NADPH-dependent FMN reductase
COCLMCBI_00772 7.9e-124
COCLMCBI_00773 3.6e-138 insK L Transposase and inactivated derivatives
COCLMCBI_00774 4.9e-43 L Transposase and inactivated derivatives
COCLMCBI_00775 3.4e-21
COCLMCBI_00776 0.0 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COCLMCBI_00777 1.6e-08 S Helix-turn-helix domain
COCLMCBI_00779 3.7e-139 L Phage integrase family
COCLMCBI_00780 2.7e-11
COCLMCBI_00782 4.6e-16
COCLMCBI_00783 5e-100 S Psort location Cytoplasmic, score 7.50
COCLMCBI_00785 5.3e-104 S Pfam PF00149
COCLMCBI_00787 7.8e-169 chr P COG2059 Chromate transport protein ChrA
COCLMCBI_00788 1.6e-188 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related
COCLMCBI_00789 3.6e-197 agxT 2.6.1.44, 2.6.1.45, 2.6.1.51 E Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
COCLMCBI_00790 2.4e-20
COCLMCBI_00791 2.1e-199 thiF 2.7.7.80, 2.8.1.11 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
COCLMCBI_00792 6.4e-241 ectP M Belongs to the BCCT transporter (TC 2.A.15) family
COCLMCBI_00793 1.2e-158 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COCLMCBI_00794 2e-138 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
COCLMCBI_00795 4.8e-12 thiS H ThiS family
COCLMCBI_00796 5.5e-203 thiO 1.4.3.19 E Glycine D-amino acid oxidases (deaminating)
COCLMCBI_00797 2.5e-101 tcsR2 K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COCLMCBI_00798 1.3e-166 2.7.13.3 T Histidine kinase
COCLMCBI_00799 5.7e-130 V ABC-type multidrug transport system, permease component
COCLMCBI_00800 5.5e-139 V ATP-binding protein
COCLMCBI_00801 1.5e-67 ectC 4.2.1.108 G Ectoine synthase
COCLMCBI_00802 5.1e-97 P Cation efflux family
COCLMCBI_00803 1e-232 V HNH endonuclease
COCLMCBI_00804 3.3e-204 mntH P Mn2 and Fe2 transporters of the NRAMP family
COCLMCBI_00805 4.5e-200 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
COCLMCBI_00806 8.4e-148 atoE I Short chain fatty acid transporter
COCLMCBI_00807 1e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COCLMCBI_00808 1.1e-149 S Protein of unknown function (DUF418)
COCLMCBI_00809 3.4e-138 hisN 3.1.3.15 G Archaeal fructose-16-bisphosphatase and related enzymes of inositol monophosphatase family
COCLMCBI_00810 1.2e-125 3.1.3.25 G Archaeal fructose-16-bisphosphatase and related enzymes of inositol monophosphatase family
COCLMCBI_00811 2.6e-192 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COCLMCBI_00812 9.7e-50 QT PucR C-terminal helix-turn-helix domain
COCLMCBI_00813 4.5e-181 Q Flavin containing amine oxidoreductase
COCLMCBI_00814 2.4e-174 S Transmembrane protein of unknown function (DUF3556)
COCLMCBI_00815 1.1e-281 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
COCLMCBI_00816 4.1e-121 ftsE D cell division ATP-binding protein
COCLMCBI_00817 2.4e-151 ftsX D Part of the ABC transporter FtsEX involved in cellular division
COCLMCBI_00818 1.2e-85 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COCLMCBI_00819 7.5e-115 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COCLMCBI_00821 1.3e-149 fatB P Periplasmic binding protein
COCLMCBI_00822 2.4e-163 fatB P ABC-type enterochelin transport system periplasmic component
COCLMCBI_00823 1.3e-166 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00824 3.7e-177 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_00825 3.5e-132 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
COCLMCBI_00826 1.9e-13
COCLMCBI_00827 1.4e-110 S membrane transporter protein
COCLMCBI_00828 0.0 ppe1 S Pfam PF00149
COCLMCBI_00829 2.2e-162 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
COCLMCBI_00830 7.9e-196 ugpB G Bacterial extracellular solute-binding protein
COCLMCBI_00831 3.7e-150 ugpE P ABC transporter permease
COCLMCBI_00832 2.6e-156 ugpA P ABC transporter permease
COCLMCBI_00833 1.4e-82 ugpQ_1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COCLMCBI_00834 2.4e-113 S Protein of unknown function (DUF3239)
COCLMCBI_00835 3.7e-304 ercc3 3.6.4.12 L DNA or RNA helicases of superfamily II
COCLMCBI_00836 1.7e-26 parD1 K Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
COCLMCBI_00837 1.1e-124 CP ABC-type Na efflux pump, permease component
COCLMCBI_00838 8.5e-138 S ABC transporter, ATP-binding protein
COCLMCBI_00839 5.4e-76
COCLMCBI_00840 4.5e-35 K Helix-turn-helix XRE-family like proteins
COCLMCBI_00841 7.6e-238 M1-1077 K Helicase conserved C-terminal domain
COCLMCBI_00842 3e-25
COCLMCBI_00843 1.8e-87 rpfA GH23 M Protein of unknown function (DUF3235)
COCLMCBI_00844 1.3e-60 cspB K Cold shock proteins
COCLMCBI_00845 6e-69 S Protein of unknown function (DUF2771)
COCLMCBI_00846 3.5e-122 2.3.2.5 M Glutamine cyclotransferase
COCLMCBI_00847 2.4e-122 S Protein of unknown function (DUF3027)
COCLMCBI_00848 9.2e-257 yjcD S permeases
COCLMCBI_00849 1.2e-146 spoU2 2.1.1.185 J rRNA methylases
COCLMCBI_00850 3.6e-125
COCLMCBI_00851 2e-153 S Protein of unknown function (DUF3071)
COCLMCBI_00852 1.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COCLMCBI_00853 7.8e-249 gltA 2.3.3.1 C Belongs to the citrate synthase family
COCLMCBI_00854 6.3e-63 fkb 5.2.1.8 O Peptidyl-prolyl cis-trans
COCLMCBI_00855 1.7e-151 dkgA 1.1.1.346 S Aldo keto reductases, related to diketogulonate reductase
COCLMCBI_00856 1.7e-54 yjcH S membrane
COCLMCBI_00857 1.9e-284 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COCLMCBI_00858 1.2e-151 M Tat pathway signal sequence domain protein
COCLMCBI_00859 1.7e-08
COCLMCBI_00860 1.9e-25 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COCLMCBI_00861 1.5e-75 K Bacterial regulatory proteins, tetR family
COCLMCBI_00862 3.7e-175 J Acetyltransferase (GNAT) domain
COCLMCBI_00864 7.4e-10 K Winged helix DNA-binding domain
COCLMCBI_00865 3.4e-35 grxA 1.20.4.3 O Glutaredoxin
COCLMCBI_00866 6.1e-67 folA 1.5.1.3 H dihydrofolate reductase
COCLMCBI_00867 8.5e-148 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COCLMCBI_00868 4.1e-144 cysQ 3.1.3.7 P Inositol monophosphatase
COCLMCBI_00869 2.5e-264 3.6.4.12 K transcriptional regulator containing an HTH domain and an
COCLMCBI_00870 0.0 lhr L Lhr-like helicases
COCLMCBI_00871 2.1e-24
COCLMCBI_00872 2e-149 nei 4.2.99.18 L formamidopyrimidine-DNA glycosylase
COCLMCBI_00873 1e-113 apl 3.1.3.1 S membrane-associated protein
COCLMCBI_00874 4.6e-285 ybdK_1 S glutamate--cysteine ligase
COCLMCBI_00875 9.4e-308 pgi 5.3.1.9 G Belongs to the GPI family
COCLMCBI_00876 9.2e-53 1.14.99.57 S Antibiotic biosynthesis monooxygenase
COCLMCBI_00877 8.7e-110
COCLMCBI_00878 1.5e-46 tyrA 1.3.1.12, 5.4.99.5 E chorismate mutase
COCLMCBI_00879 0.0 pcrA 3.6.4.12 L Superfamily I DNA and RNA helicases
COCLMCBI_00880 4.5e-123 M Peptidase, M23
COCLMCBI_00881 1.2e-208 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_00882 3.3e-116 mepA M Membrane proteins related to metalloendopeptidases
COCLMCBI_00883 2.2e-164
COCLMCBI_00884 1e-83 purN 2.1.2.2, 2.1.2.3, 3.5.4.10 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COCLMCBI_00885 9e-260 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COCLMCBI_00886 2.2e-66 KLT serine threonine protein kinase
COCLMCBI_00887 1.4e-113 V Beta-lactamase
COCLMCBI_00888 2.2e-114 amtR K Transcriptional regulator
COCLMCBI_00889 1.9e-156 V Beta-lactamase
COCLMCBI_00890 1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COCLMCBI_00891 1.8e-47 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COCLMCBI_00892 3.8e-23 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COCLMCBI_00893 1.2e-35 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COCLMCBI_00894 5.8e-19 arsB P COG1055 Na H antiporter NhaD and related arsenite permeases
COCLMCBI_00895 1.1e-136 S Protein of unknown function (DUF418)
COCLMCBI_00896 6.2e-47 rpmE2 J Ribosomal protein L31
COCLMCBI_00897 1.1e-23 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COCLMCBI_00898 2.2e-120 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COCLMCBI_00899 1.7e-231 T PhoQ Sensor
COCLMCBI_00900 2.8e-179 pepD O Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
COCLMCBI_00901 4.1e-93 moaB 4.2.1.96 H Molybdenum cofactor biosynthesis protein
COCLMCBI_00903 6.9e-61 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COCLMCBI_00904 3.6e-42 cpaB U SAF
COCLMCBI_00905 1.2e-82 fthC 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COCLMCBI_00906 1.2e-169 galU 2.7.7.9 M UDP-glucose pyrophosphorylase
COCLMCBI_00907 2e-220 moeA 2.10.1.1 H Molybdenum cofactor synthesis
COCLMCBI_00908 2.6e-126 rimJ 2.3.1.128 J Acetyltransferases including N-acetylases of ribosomal proteins
COCLMCBI_00909 4.3e-94
COCLMCBI_00910 2.6e-97 Q Domain of unknown function (DUF4442)
COCLMCBI_00911 6.5e-309 ilvG 2.2.1.6 EH Belongs to the TPP enzyme family
COCLMCBI_00912 1.1e-133 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
COCLMCBI_00913 1.3e-61 catD S membrane
COCLMCBI_00914 8.3e-106 sigC S integral membrane protein
COCLMCBI_00915 2.3e-295 pmt 2.4.1.109 GT39 O Dolichyl-phosphate-mannose--protein
COCLMCBI_00916 8.4e-127 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COCLMCBI_00917 6e-258 betP M Belongs to the BCCT transporter (TC 2.A.15) family
COCLMCBI_00918 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COCLMCBI_00919 2.3e-66 S Domain of unknown function (DUF3806)
COCLMCBI_00920 1.7e-146 tatD L Mg-dependent DNase
COCLMCBI_00921 3.3e-190 yabE S protein conserved in bacteria
COCLMCBI_00922 1.5e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COCLMCBI_00923 1.4e-157 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COCLMCBI_00924 0.0 yjjK S ATPase components of ABC transporters with duplicated ATPase domains
COCLMCBI_00925 8.6e-234 3.5.1.23 S Neutral/alkaline non-lysosomal ceramidase, N-terminal
COCLMCBI_00926 1.4e-53 S Antibiotic biosynthesis monooxygenase
COCLMCBI_00927 1.6e-160 ppk2 2.7.4.1 S polyphosphate kinase
COCLMCBI_00928 7.1e-98 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COCLMCBI_00929 2.8e-135 supH S hydrolases of the HAD superfamily
COCLMCBI_00930 1.8e-176 echA3 4.2.1.17 I Enoyl-CoA hydratase carnithine racemase
COCLMCBI_00931 1.9e-275 gapA 1.2.1.12, 4.1.1.32 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COCLMCBI_00932 1.7e-219 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G isomerase
COCLMCBI_00934 8e-205 sqdX M Glycosyltransferase
COCLMCBI_00935 9.8e-230 sqdB 3.13.1.1 GM Sulfolipid biosynthesis protein
COCLMCBI_00936 0.0 MA20_22130 S FAD-binding dehydrogenase
COCLMCBI_00938 6.5e-216 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
COCLMCBI_00939 9.2e-218 EGP Permeases of the major facilitator superfamily
COCLMCBI_00940 5.9e-130 V antibiotic catabolic process
COCLMCBI_00941 4.8e-64
COCLMCBI_00943 5.6e-201 rbn S membrane
COCLMCBI_00944 1e-159 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
COCLMCBI_00945 6.6e-159 S esterase of the alpha-beta hydrolase superfamily
COCLMCBI_00946 6e-160 S esterase of the alpha-beta hydrolase superfamily
COCLMCBI_00947 3.9e-253 V endonuclease
COCLMCBI_00948 9.2e-250 ybhI P Sodium:sulfate symporter transmembrane region
COCLMCBI_00949 7.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COCLMCBI_00951 7e-98 S reductase
COCLMCBI_00952 2.8e-109 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COCLMCBI_00955 9.8e-164 ycf23 1.1.1.205, 1.13.12.16 S 2-nitropropane dioxygenase
COCLMCBI_00956 8e-49
COCLMCBI_00957 8e-97 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COCLMCBI_00958 4.6e-99 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COCLMCBI_00959 1.1e-166 EGP Permeases of the major facilitator superfamily
COCLMCBI_00960 9.5e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COCLMCBI_00961 3.1e-125 aroP E Gamma-aminobutyrate permease and related permeases
COCLMCBI_00962 1.5e-80 aroP E Gamma-aminobutyrate permease and related permeases
COCLMCBI_00963 1.8e-184 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COCLMCBI_00964 8.4e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COCLMCBI_00966 8.8e-189 EGP Major facilitator Superfamily
COCLMCBI_00967 2.4e-268 Q Tat pathway signal sequence domain protein
COCLMCBI_00968 7.3e-10 3.6.4.13 M Cell wall-binding repeat protein
COCLMCBI_00971 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COCLMCBI_00972 8.9e-162 proX M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COCLMCBI_00973 2.7e-115 proZ P ABC transporter permease
COCLMCBI_00974 7.1e-94 proW P ABC-type proline glycine betaine transport systems, permease component
COCLMCBI_00975 1.1e-139 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
COCLMCBI_00976 1.2e-101 S Abortive infection protein
COCLMCBI_00977 1.7e-232 ybjT GM NmrA-like family
COCLMCBI_00979 9.9e-178 btrU S Suppressor of fused protein (SUFU)
COCLMCBI_00980 6.9e-135 S membrane
COCLMCBI_00981 6.3e-247 L Transposase and inactivated derivatives
COCLMCBI_00982 5.2e-69
COCLMCBI_00983 3.4e-86 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COCLMCBI_00984 4.4e-61 S Domain of unknown function (DUF4307)
COCLMCBI_00985 5e-170 mca 3.5.1.115 S A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
COCLMCBI_00986 2.8e-45
COCLMCBI_00987 1.2e-135 uppS1 2.5.1.31, 2.5.1.68 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COCLMCBI_00988 8.6e-173 coaA 2.7.1.33 F Pantothenic acid kinase
COCLMCBI_00989 3.6e-246 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COCLMCBI_00990 5.9e-35
COCLMCBI_00991 2.7e-91 K Transcriptional regulator
COCLMCBI_00992 1.9e-64 M protein potentially involved in peptidoglycan biosynthesis
COCLMCBI_00993 2.1e-252 phoH T ATPase related to phosphate starvation-inducible protein PhoH
COCLMCBI_00994 7.8e-105 ywnH 2.3.1.183 M Sortase and related acyltransferases
COCLMCBI_00995 3.2e-265 bmr3 EGP Major facilitator Superfamily
COCLMCBI_00996 1.1e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COCLMCBI_00997 1.8e-179 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
COCLMCBI_00998 2.9e-85 S Protein of unknown function (DUF4245)
COCLMCBI_00999 1e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCLMCBI_01000 1.1e-223 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COCLMCBI_01001 3.2e-146 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COCLMCBI_01002 9.9e-52 E amino acid transport
COCLMCBI_01003 3.5e-165 rmuC S DNA recombination protein
COCLMCBI_01004 1.2e-238 S permease
COCLMCBI_01005 2.6e-254 S Pfam PF00149
COCLMCBI_01006 1.5e-192 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COCLMCBI_01007 1.5e-25
COCLMCBI_01008 8.9e-262 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COCLMCBI_01009 2.4e-68 K Transcriptional regulator
COCLMCBI_01010 9.5e-14 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COCLMCBI_01011 3.5e-89 1.3.1.45 GM epimerase dehydratase
COCLMCBI_01012 6.7e-44 S Bacteriocin (Lactococcin_972)
COCLMCBI_01013 0.0
COCLMCBI_01014 4.2e-130 V ABC transporter, ATP-binding protein
COCLMCBI_01015 1.6e-42 higB S Plasmid maintenance system killer protein
COCLMCBI_01016 1.6e-46 higA K Plasmid maintenance system antidote protein
COCLMCBI_01017 1.7e-70 S Putative glycolipid-binding
COCLMCBI_01019 1.2e-129 irp6C 3.6.3.34 HP ATP-binding protein
COCLMCBI_01020 1e-172 irp6B U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COCLMCBI_01021 1e-208 irp6A P Periplasmic binding protein
COCLMCBI_01022 3.7e-49 prfA J Peptide chain release factor I
COCLMCBI_01023 1.5e-56 phnB2 S protein conserved in bacteria
COCLMCBI_01024 8.5e-46 chr P COG2059 Chromate transport protein ChrA
COCLMCBI_01025 3.6e-135 insK L Transposase and inactivated derivatives
COCLMCBI_01026 7e-58 L Helix-turn-helix domain
COCLMCBI_01027 3.9e-62 cskE S Anti-sigma-K factor rskA
COCLMCBI_01028 1.1e-85 sigK K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_01030 2.8e-243 dipZ CO Cytochrome C biogenesis protein transmembrane region
COCLMCBI_01031 3.3e-37 higA K Plasmid maintenance system antidote protein
COCLMCBI_01032 1.7e-53 prfA J Peptide chain release factor I
COCLMCBI_01033 9.5e-101 S Putative glycolipid-binding
COCLMCBI_01034 4.7e-29 XK27_10495 DJ ParE toxin of type II toxin-antitoxin system, parDE
COCLMCBI_01035 2.3e-20
COCLMCBI_01036 1.3e-11 S Domain of unknown function (DUF1707)
COCLMCBI_01037 1.1e-133 tipA K transcriptional regulators
COCLMCBI_01038 2.1e-33
COCLMCBI_01039 2.1e-253 S protein with a von Willebrand factor type A (vWA) domain
COCLMCBI_01040 6.7e-238 chlI 6.6.1.1 H COG1239 Mg-chelatase subunit ChlI
COCLMCBI_01041 3.9e-88 3.1.3.3, 3.1.3.73, 5.4.2.12 G COG0406 Fructose-2,6-bisphosphatase
COCLMCBI_01042 1e-120 BDLTU Phosphatidylinositol
COCLMCBI_01043 9.1e-90 C Protein of unknown function, DUF488
COCLMCBI_01044 1.6e-115 arsO P flavoprotein involved in K transport
COCLMCBI_01045 0.0 cadA P E1-E2 ATPase
COCLMCBI_01046 9.3e-59 cmtR K transcriptional
COCLMCBI_01047 5.7e-10 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related
COCLMCBI_01048 2.1e-77 S Protein of unknown function DUF2625
COCLMCBI_01049 1.3e-46 prfA J Peptide chain release factor I
COCLMCBI_01050 3.7e-99 C Protein of unknown function, DUF488
COCLMCBI_01051 7.8e-67 E glyoxalase
COCLMCBI_01052 3.3e-31 S Ribbon-helix-helix protein, copG family
COCLMCBI_01053 3.4e-82
COCLMCBI_01054 7.6e-10
COCLMCBI_01055 3.1e-86 S Putative glycolipid-binding
COCLMCBI_01057 1.1e-79 S Domain of unknown function (DUF1707)
COCLMCBI_01058 1.6e-79 S membrane
COCLMCBI_01059 6e-142 S CAAX amino terminal protease family protein
COCLMCBI_01060 5.3e-170 tcsS5 T Histidine kinase
COCLMCBI_01061 2.2e-101 T cheY-homologous receiver domain
COCLMCBI_01062 1e-196 yhaZ L DNA alkylation repair
COCLMCBI_01065 7.6e-104 ku L Ku70/Ku80 beta-barrel domain
COCLMCBI_01066 1.8e-283 ligD 6.5.1.1, 6.5.1.6, 6.5.1.7 L DNA polymerase LigD polymerase domain
COCLMCBI_01067 3.4e-273 yhgE S YhgE Pip domain protein
COCLMCBI_01068 1.7e-125 yplQ S protein, hemolysin III
COCLMCBI_01069 2.9e-71 speE 2.5.1.16 E spermidine synthase
COCLMCBI_01070 5e-159 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COCLMCBI_01071 1.3e-233 EGP the major facilitator superfamily
COCLMCBI_01072 8.7e-303 F Belongs to the 5'-nucleotidase family
COCLMCBI_01073 0.0 S protein with a von Willebrand factor type A (vWA) domain
COCLMCBI_01074 2.4e-259 chlI 6.6.1.1 H COG1239 Mg-chelatase subunit ChlI
COCLMCBI_01075 1.6e-100 3.1.3.3, 3.1.3.73, 5.4.2.12 G COG0406 Fructose-2,6-bisphosphatase
COCLMCBI_01076 8.5e-139 BDLTU Phosphatidylinositol
COCLMCBI_01077 6.8e-77 tcmJ G Cupin domain
COCLMCBI_01078 1.4e-47 S Domain of unknown function (DUF4298)
COCLMCBI_01079 2e-12 S Domain of unknown function (DUF4298)
COCLMCBI_01080 2.4e-128 M translation initiation factor activity
COCLMCBI_01081 9.8e-137 yedI S protein conserved in bacteria
COCLMCBI_01082 1.4e-56 S Uncharacterized protein conserved in bacteria (DUF2218)
COCLMCBI_01083 3.4e-98 S Protein of unknown function (DUF402)
COCLMCBI_01084 3.7e-92
COCLMCBI_01085 0.0 typA T GTP-binding protein
COCLMCBI_01086 4e-256 lpqW E ABC transporter, substrate-binding protein, family 5
COCLMCBI_01087 1.8e-162 mshB 3.5.1.103 S Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway
COCLMCBI_01088 1.8e-12
COCLMCBI_01089 1.7e-59 fdxA C ferredoxin
COCLMCBI_01090 6.5e-196 dapC E Aspartate tyrosine aromatic aminotransferase
COCLMCBI_01091 4.5e-103 MA20_09515 2.4.1.83 GT2 S GtrA-like protein
COCLMCBI_01092 4.7e-194 L HNH endonuclease domain protein
COCLMCBI_01093 1.8e-173 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
COCLMCBI_01094 1.6e-239 aroP E amino acid
COCLMCBI_01095 1.5e-240 aroP E amino acid
COCLMCBI_01096 7.4e-172 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
COCLMCBI_01097 1.5e-200 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COCLMCBI_01098 2e-154 fmt2 3.2.2.10 S Belongs to the LOG family
COCLMCBI_01099 3.8e-151 folP2 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COCLMCBI_01100 1.1e-122 gpgS 2.4.1.266, 2.4.1.268 GT81 M Glycosyltransferases involved in cell wall biogenesis
COCLMCBI_01101 2.3e-49
COCLMCBI_01102 1.7e-18 S Protein of unknown function (DUF3117)
COCLMCBI_01103 6e-152 rrmA 2.1.1.187 Q SAM-dependent
COCLMCBI_01104 5.4e-264 scrB 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
COCLMCBI_01105 5.8e-219 glgA 2.4.1.342 GT4 G Glycogen synthase, Corynebacterium family
COCLMCBI_01106 1.8e-202 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COCLMCBI_01107 1.5e-97 safC S O-methyltransferase
COCLMCBI_01108 2.1e-106 sigE K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_01109 6.2e-48 cseE 2.1.1.63 K AntiSigma factor
COCLMCBI_01110 1.9e-54 tatB U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation
COCLMCBI_01111 4.4e-203 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
COCLMCBI_01112 5.1e-64
COCLMCBI_01113 3e-44
COCLMCBI_01114 0.0 sucA 1.2.4.2, 4.1.1.71 C 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes
COCLMCBI_01115 0.0 V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_01116 4.5e-164 S 5-oxoprolinase (ATP-hydrolyzing) activity
COCLMCBI_01117 4.9e-306 lipT CE10 I Belongs to the type-B carboxylesterase lipase family
COCLMCBI_01118 1.1e-126
COCLMCBI_01119 8.3e-79
COCLMCBI_01120 1.5e-199 blt EGP Major facilitator Superfamily
COCLMCBI_01121 9.1e-189 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COCLMCBI_01123 5.1e-56 V HNH endonuclease
COCLMCBI_01124 1.8e-174 dcm 2.1.1.37 L DNA restriction-modification system
COCLMCBI_01125 1.7e-53 nudG 3.6.1.55, 3.6.1.65 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_01126 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_01127 9e-50 L Transposase and inactivated derivatives
COCLMCBI_01128 2e-141 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_01129 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_01130 9e-50 L Transposase and inactivated derivatives
COCLMCBI_01131 4.1e-88 repB EP Plasmid replication protein
COCLMCBI_01137 3.4e-115 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
COCLMCBI_01138 1.2e-143 cmrA S Belongs to the short-chain dehydrogenases reductases (SDR) family
COCLMCBI_01139 1.1e-28 yozG K Cro/C1-type HTH DNA-binding domain
COCLMCBI_01140 8.4e-102
COCLMCBI_01144 0.0 P CytoChrome c oxidase Caa3 assembly factor
COCLMCBI_01145 6.5e-89 L Single-stranded DNA-binding protein
COCLMCBI_01146 0.0 yjjK S ATPase components of ABC transporters with duplicated ATPase domains
COCLMCBI_01147 5.4e-66 S Thioesterase
COCLMCBI_01148 1.4e-83
COCLMCBI_01149 2.2e-217 gulO 1.1.3.8 C FAD FMN-containing dehydrogenases
COCLMCBI_01150 7.1e-196 E Alanine racemase, N-terminal domain
COCLMCBI_01151 3.9e-74 glbO S Hemoglobin-like protein
COCLMCBI_01152 5.7e-222 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cystathionine beta-lyases cystathionine
COCLMCBI_01153 0.0 pepN 3.4.11.2 E aminopeptidase
COCLMCBI_01154 9.2e-115 yjbH Q DSBA oxidoreductase
COCLMCBI_01155 1e-84 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
COCLMCBI_01156 8.7e-65 K Psort location Cytoplasmic, score
COCLMCBI_01157 8.9e-57 S Domain of unknown function (DUF4440)
COCLMCBI_01158 5.7e-33
COCLMCBI_01159 1.2e-12
COCLMCBI_01160 9.6e-164 S N-terminal domain of galactosyltransferase
COCLMCBI_01161 1.2e-155 S Glycosyl transferase, family 2
COCLMCBI_01162 5e-159
COCLMCBI_01163 6.6e-168 S Glycosyl transferase, family 2
COCLMCBI_01164 1.9e-211 M Glycosyltransferase Family 4
COCLMCBI_01165 4.9e-171 S Glycosyl transferase, family 2
COCLMCBI_01166 7.7e-135 S Glycosyl transferase, family 2
COCLMCBI_01167 6.7e-176 ycdO P periplasmic lipoprotein involved in iron transport
COCLMCBI_01168 1.4e-131 4.2.1.17, 5.3.3.18 I Enoyl-CoA hydratase/isomerase
COCLMCBI_01169 3.1e-181 MA20_15180 1.13.12.16 S Nitronate monooxygenase
COCLMCBI_01170 1.6e-97
COCLMCBI_01173 6.4e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COCLMCBI_01174 1.2e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COCLMCBI_01175 7.1e-107 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COCLMCBI_01176 1.4e-47
COCLMCBI_01177 6.3e-53
COCLMCBI_01178 2.7e-140 pcaD 3.1.1.24, 3.4.11.5, 4.1.1.44 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COCLMCBI_01179 2.3e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COCLMCBI_01180 3.4e-141 ytfA K Transcriptional regulator
COCLMCBI_01181 9.7e-183 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
COCLMCBI_01182 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COCLMCBI_01183 8.5e-260 folC 6.3.2.12, 6.3.2.17 H Folylpolyglutamate synthase
COCLMCBI_01184 1.5e-77 S Protein of unknown function (DUF4233)
COCLMCBI_01185 4e-212 thlA 2.3.1.9 I Belongs to the thiolase family
COCLMCBI_01186 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
COCLMCBI_01187 4.7e-46 J Acetyltransferases including N-acetylases of ribosomal proteins
COCLMCBI_01188 1.6e-147 S Uncharacterized protein conserved in bacteria (DUF2262)
COCLMCBI_01189 5.1e-226 1.3.8.6 I Acyl-CoA dehydrogenases
COCLMCBI_01190 4.7e-224 1.3.8.6 I Acyl-CoA dehydrogenases
COCLMCBI_01191 2.1e-280 fadD7 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_01192 2.2e-40
COCLMCBI_01193 8.4e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
COCLMCBI_01194 4.3e-294 phoD 3.1.3.1 P Alkaline phosphatase D
COCLMCBI_01195 5.6e-301 rne 3.1.26.12 J Ribonucleases G and E
COCLMCBI_01196 8.3e-49
COCLMCBI_01197 0.0 S Dynamin family
COCLMCBI_01198 1.1e-259 S Dynamin family
COCLMCBI_01199 3.3e-134 hscA O Belongs to the heat shock protein 70 family
COCLMCBI_01200 2.1e-198 hscA O Belongs to the heat shock protein 70 family
COCLMCBI_01201 2.5e-43 hscA O Belongs to the heat shock protein 70 family
COCLMCBI_01202 8.1e-91 K Belongs to the sigma-70 factor family. ECF subfamily
COCLMCBI_01204 1.2e-46 rplU J This protein binds to 23S rRNA in the presence of protein L20
COCLMCBI_01205 5.2e-54 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COCLMCBI_01206 1.1e-278 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COCLMCBI_01207 1.4e-193 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COCLMCBI_01208 2e-137 pdxB 1.1.1.399, 1.1.1.95 EH Phosphoglycerate dehydrogenase and related dehydrogenases
COCLMCBI_01210 5.5e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COCLMCBI_01211 5.3e-98
COCLMCBI_01213 3.9e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COCLMCBI_01214 1.7e-76 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COCLMCBI_01215 3.7e-109 gpmB 3.1.3.73, 3.1.3.85 G Belongs to the phosphoglycerate mutase family
COCLMCBI_01216 1.9e-128 S protein conserved in bacteria
COCLMCBI_01217 5.7e-89 comEA L DNA uptake protein and related DNA-binding proteins
COCLMCBI_01218 2.5e-228 comE L membrane metal-binding protein
COCLMCBI_01219 4.5e-169 holA 2.7.7.7 L DNA polymerase III, delta' subunit
COCLMCBI_01220 8.8e-53 S ankyrin repeat
COCLMCBI_01221 1.6e-93 rhtC E threonine efflux protein
COCLMCBI_01222 6.3e-123 CE1 Q Poly(3-hydroxybutyrate) depolymerase
COCLMCBI_01223 2.8e-36 rpsT J Binds directly to 16S ribosomal RNA
COCLMCBI_01224 5.2e-93 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COCLMCBI_01225 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COCLMCBI_01226 4.7e-91 ligT 3.1.4.58 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
COCLMCBI_01227 1.7e-119 S CAAX protease self-immunity
COCLMCBI_01228 0.0 betP2 M Belongs to the BCCT transporter (TC 2.A.15) family
COCLMCBI_01229 6.6e-248 pip 3.4.11.5 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COCLMCBI_01231 1.9e-137 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COCLMCBI_01232 1.3e-238 phoC I Membrane-associated phospholipid phosphatase
COCLMCBI_01233 1.1e-245 oppDF2 P Belongs to the ABC transporter superfamily
COCLMCBI_01234 7e-139 oppC4 P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COCLMCBI_01235 4.9e-152 oppB4 P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COCLMCBI_01236 1.3e-255 E ABC-type dipeptide transport system periplasmic component
COCLMCBI_01237 2.3e-126 K transcriptional
COCLMCBI_01238 2.4e-176 yvbT C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related
COCLMCBI_01239 1.1e-80 K transcriptional
COCLMCBI_01240 1.3e-135 E Glycine D-amino acid oxidases (deaminating)
COCLMCBI_01241 7.6e-108 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
COCLMCBI_01242 1.2e-98 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COCLMCBI_01243 1.6e-180 phnE_2 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
COCLMCBI_01244 5.2e-79 S HAD-hyrolase-like
COCLMCBI_01245 5.8e-98 1.1.1.1 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COCLMCBI_01246 7.6e-253 brnQ E Component of the transport system for branched-chain amino acids
COCLMCBI_01247 1.8e-177 treS 2.4.1.18, 2.7.1.175, 3.2.1.1, 5.4.99.16 CBM48,GH13 G protein, probably involved in trehalose biosynthesis
COCLMCBI_01248 0.0 treS 3.2.1.1, 5.4.99.16 GH13 G Trehalose synthase
COCLMCBI_01249 6.1e-211 aecD 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
COCLMCBI_01251 0.0 exsA V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_01252 4.9e-88
COCLMCBI_01253 9.5e-90 idi 5.3.3.2 I Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
COCLMCBI_01254 4.8e-235 estC CE10 I Belongs to the type-B carboxylesterase lipase family
COCLMCBI_01256 3.8e-16
COCLMCBI_01257 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
COCLMCBI_01258 0.0 acsbg2 6.2.1.3 I Long-chain acyl-CoA synthetases (AMP-forming)
COCLMCBI_01259 0.0 acsbg2 6.2.1.3 I Long-chain acyl-CoA synthetases (AMP-forming)
COCLMCBI_01260 1.2e-94
COCLMCBI_01261 1.5e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
COCLMCBI_01262 4.6e-172 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COCLMCBI_01263 2e-192 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COCLMCBI_01264 2.8e-118 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COCLMCBI_01265 1.5e-168 phoH T Phosphate starvation-inducible protein PhoH
COCLMCBI_01266 8e-108 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COCLMCBI_01267 4.3e-251 corC S Hemolysins and related proteins containing CBS domains
COCLMCBI_01268 4e-156 pdxY 2.7.1.35 H Belongs to the pyridoxine kinase family
COCLMCBI_01269 3.6e-191 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COCLMCBI_01270 9.9e-132 recO L Involved in DNA repair and RecF pathway recombination
COCLMCBI_01271 2.9e-134 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COCLMCBI_01272 5.1e-72 zur P Belongs to the Fur family
COCLMCBI_01273 5.7e-72 znr K transcriptional
COCLMCBI_01274 2.3e-275 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
COCLMCBI_01275 1.4e-88
COCLMCBI_01276 3.8e-09
COCLMCBI_01277 5e-266 U TPM domain
COCLMCBI_01278 5.2e-237 dgt 3.1.5.1 F Belongs to the dGTPase family. Type 2 subfamily
COCLMCBI_01279 7.7e-15 K Psort location Cytoplasmic, score
COCLMCBI_01280 2.5e-23 rnaSA 3.1.27.3 F Guanyl-specific ribonuclease Sa
COCLMCBI_01281 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COCLMCBI_01282 1.9e-102 3.6.1.66 S MazG nucleotide pyrophosphohydrolase domain protein
COCLMCBI_01283 1e-27 S Alpha helical Porin B
COCLMCBI_01284 5.8e-131 lpqU M Membrane-bound lytic murein transglycosylase B
COCLMCBI_01285 2.3e-08
COCLMCBI_01287 3.7e-235 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COCLMCBI_01288 3.7e-45 divIC D septum formation initiator
COCLMCBI_01289 7.6e-97 ppx2 3.6.1.11, 3.6.1.40 S Septum formation initiator family protein
COCLMCBI_01290 4.7e-158 ppx 3.6.1.11, 3.6.1.40 FP Exopolyphosphatase
COCLMCBI_01291 5.5e-40
COCLMCBI_01294 2.7e-91
COCLMCBI_01295 1.2e-219 MA20_32325 3.4.17.11 E Peptidase dimerisation domain
COCLMCBI_01296 6.1e-151 bla V Beta-lactamase class C and other penicillin binding proteins
COCLMCBI_01297 1.5e-142 S membrane
COCLMCBI_01299 2.1e-14 IQ acyl carrier protein
COCLMCBI_01300 3.5e-172 S hydrolases or acyltransferases alpha beta hydrolase superfamily
COCLMCBI_01301 1e-292 ethA 1.14.13.22 P flavoprotein involved in K transport
COCLMCBI_01303 6e-18 L Excalibur calcium-binding domain
COCLMCBI_01308 0.0 aceE 1.2.4.1 C component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
COCLMCBI_01309 1.1e-68 S Protein of unknown function (DUF3052)
COCLMCBI_01312 3e-144 surf1 S SURF1-like protein
COCLMCBI_01313 9.5e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCLMCBI_01314 8.8e-116 pgp 3.1.3.18 S HAD hydrolase, family IA, variant 1
COCLMCBI_01315 8.5e-215 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COCLMCBI_01316 7.1e-113 CP_0228 3.5.4.16 S Zn-ribbon protein
COCLMCBI_01317 1.6e-197 rnhA 3.1.26.4, 3.1.3.3, 3.1.3.73, 3.1.3.85, 5.4.2.12 GL Ribonuclease HI
COCLMCBI_01318 6e-256 rnr K Exoribonuclease R
COCLMCBI_01319 3.3e-193 galK 2.7.1.157, 2.7.1.6 G Belongs to the GHMP kinase family
COCLMCBI_01320 7.3e-32
COCLMCBI_01321 5.2e-93 K Psort location Cytoplasmic, score
COCLMCBI_01322 2.4e-277 S CHAD domain protein
COCLMCBI_01323 3.7e-254 glnA2 6.3.1.2 E glutamine synthetase
COCLMCBI_01324 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
COCLMCBI_01325 8.3e-48
COCLMCBI_01326 2.6e-272 thrC 4.2.3.1 E Threonine synthase
COCLMCBI_01327 5.2e-24
COCLMCBI_01328 5.1e-171 O Trypsin
COCLMCBI_01329 1.4e-107
COCLMCBI_01330 1.2e-91 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_01331 3.6e-103 M Glycosyl hydrolases family 25
COCLMCBI_01332 3.4e-50
COCLMCBI_01333 7.6e-161 mae1 P Tellurite resistance protein and related permeases
COCLMCBI_01335 2e-45 S CAAX protease self-immunity
COCLMCBI_01336 9.2e-283 glnA 6.3.1.2 E glutamine synthetase
COCLMCBI_01337 4.3e-80 S RDD family
COCLMCBI_01339 1.1e-134 S Domain of unknown function (DUF4191)
COCLMCBI_01340 3.4e-175 I MaoC like domain
COCLMCBI_01341 5.4e-245 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COCLMCBI_01342 3.1e-237 fadI 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
COCLMCBI_01343 0.0 acx 1.3.3.6 I Acyl-CoA dehydrogenases
COCLMCBI_01344 7.7e-205 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
COCLMCBI_01345 3.4e-132 lipB 2.3.1.181 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
COCLMCBI_01346 4.3e-65 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
COCLMCBI_01347 1.3e-201 gcvT 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
COCLMCBI_01348 0.0 gcvP 1.4.4.2 E Belongs to the GcvP family
COCLMCBI_01349 1.2e-310 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COCLMCBI_01350 1.1e-258 sucB 2.3.1.61 C Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes
COCLMCBI_01351 1e-64
COCLMCBI_01352 1.5e-278 pepA 3.4.11.1 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
COCLMCBI_01353 4.3e-203 ilvE 2.6.1.42 EH Branched-chain amino acid aminotransferase
COCLMCBI_01354 2.3e-166 cobT 2.4.2.21 H the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
COCLMCBI_01355 2.4e-101 S Protein of unknown function (DUF3043)
COCLMCBI_01356 2.6e-58 erpA S Belongs to the HesB IscA family
COCLMCBI_01357 0.0 asnB 6.3.5.4 E Asparagine synthase
COCLMCBI_01358 7.3e-155 ctaC 1.9.3.1 C Heme copper-type cytochrome quinol oxidases subunit 2
COCLMCBI_01359 3.8e-75 ctaF C Belongs to the cytochrome c oxidase bacterial subunit CtaF family
COCLMCBI_01360 1.9e-100 ctaE 1.9.3.1 C Heme copper-type cytochrome quinol oxidase subunit 3
COCLMCBI_01361 3e-156 qcrC C cytochrome C
COCLMCBI_01362 1.1e-239 qcrA C C reductase
COCLMCBI_01363 2.3e-311 petD C cytochrome b subunit
COCLMCBI_01364 3.8e-86 M NlpC/P60 family
COCLMCBI_01365 1.1e-136 M Cell wall-associated hydrolases
COCLMCBI_01366 2.2e-175 pimB 2.4.1.346, 3.2.1.8 GT4 M Glycosyltransferase, group 1 family protein
COCLMCBI_01367 2.4e-170 glk 2.7.1.2 G Transcriptional regulator sugar kinase
COCLMCBI_01368 2.5e-146 plsC 2.3.1.51 I Acyltransferase
COCLMCBI_01369 2e-94 L Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA
COCLMCBI_01370 3.4e-266 aroG 2.5.1.54 E Belongs to the class-II DAHP synthase family
COCLMCBI_01371 6.1e-177 KLT serine threonine protein kinase
COCLMCBI_01372 4.1e-57 S transcriptional regulator
COCLMCBI_01373 1.1e-245 mptA S Carotene biosynthesis associated membrane protein
COCLMCBI_01374 2.9e-191 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
COCLMCBI_01375 5.4e-96 K GNAT family
COCLMCBI_01376 5.6e-58
COCLMCBI_01377 6.8e-55 S Protein of unknown function (DUF3040)
COCLMCBI_01378 1.5e-74 mraZ K Belongs to the MraZ family
COCLMCBI_01379 6.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COCLMCBI_01380 8.6e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
COCLMCBI_01381 0.0 ftsI 3.4.16.4 M Cell division protein FtsI penicillin-binding protein
COCLMCBI_01382 1.7e-250 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COCLMCBI_01383 4.7e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COCLMCBI_01384 4.1e-198 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COCLMCBI_01385 1.3e-239 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COCLMCBI_01386 6.7e-238 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
COCLMCBI_01387 5.3e-177 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COCLMCBI_01388 1.8e-246 murC 6.3.2.8 M Belongs to the MurCDEF family
COCLMCBI_01389 4.6e-96 ftsQ 6.3.2.4 D Cell division protein FtsQ
COCLMCBI_01390 3.5e-207 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COCLMCBI_01391 1e-114 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
COCLMCBI_01392 6.4e-120 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COCLMCBI_01393 2.5e-55 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COCLMCBI_01394 2.3e-39 yggT S Integral membrane protein
COCLMCBI_01395 7.1e-31 ag84 D Cell division initiation protein
COCLMCBI_01396 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COCLMCBI_01397 1.9e-131
COCLMCBI_01398 1.8e-230 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COCLMCBI_01399 6.3e-117 ansA 3.5.1.1 EJ L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
COCLMCBI_01400 1.9e-79
COCLMCBI_01401 1.2e-302 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
COCLMCBI_01402 5.8e-125
COCLMCBI_01403 1.1e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COCLMCBI_01404 1.2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COCLMCBI_01405 1.4e-63
COCLMCBI_01406 9.1e-156 macA M Barrel-sandwich domain of CusB or HlyD membrane-fusion
COCLMCBI_01407 1.6e-137 macB V ABC transporter, ATP-binding protein
COCLMCBI_01408 9.1e-189 yknZ V Efflux ABC transporter, permease protein
COCLMCBI_01409 0.0 dnaE 2.7.7.7 L DNA polymerase
COCLMCBI_01410 2.4e-28
COCLMCBI_01411 1.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COCLMCBI_01412 0.0 treZ 3.2.1.141 CBM48,GH13 G 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase
COCLMCBI_01413 1.6e-101 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
COCLMCBI_01414 9.8e-33
COCLMCBI_01415 2.3e-60 hslR 5.4.99.23, 5.4.99.24 J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
COCLMCBI_01416 2.2e-151 S Protein of unknown function (DUF1266)
COCLMCBI_01417 7.7e-14
COCLMCBI_01419 0.0 treY 2.4.1.25, 5.4.99.15 GH13,GH77 G Maltooligosyl trehalose synthase
COCLMCBI_01420 1.4e-97 S Protein of unknown function (DUF1266)
COCLMCBI_01421 1.9e-12
COCLMCBI_01423 5.2e-85
COCLMCBI_01424 4.1e-188 ligA 2.7.7.7, 6.5.1.2 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
COCLMCBI_01425 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
COCLMCBI_01426 6.7e-80 tetR K Transcriptional regulator
COCLMCBI_01427 1.3e-96
COCLMCBI_01428 1.7e-29
COCLMCBI_01429 1.4e-213 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COCLMCBI_01430 3e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COCLMCBI_01431 1.1e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
COCLMCBI_01432 2.4e-07
COCLMCBI_01433 8.4e-197 EGP Major facilitator Superfamily
COCLMCBI_01434 1.2e-117 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COCLMCBI_01435 3.6e-129 hisA 5.3.1.16, 5.3.1.24 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
COCLMCBI_01436 2.5e-141 impA 3.1.3.25 G Archaeal fructose-16-bisphosphatase and related enzymes of inositol monophosphatase family
COCLMCBI_01437 3.4e-138 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COCLMCBI_01438 6.1e-61 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
COCLMCBI_01439 9.9e-107 S Trp region conserved
COCLMCBI_01440 2.7e-146 trpC 4.1.1.48 E Indole-3-glycerol phosphate synthase
COCLMCBI_01441 6.3e-168 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COCLMCBI_01442 1.5e-264 pyk 2.7.1.40 G Belongs to the pyruvate kinase family
COCLMCBI_01443 0.0 uvrA2 L Excinuclease ATPase subunit
COCLMCBI_01444 1.8e-125 styA 2.6.1.42, 3.2.1.21 GH3 EH Amino-transferase class IV
COCLMCBI_01445 0.0 pabB 2.6.1.85, 4.1.3.38, 5.4.4.2 HQ Anthranilate synthase component I, N terminal region
COCLMCBI_01446 2.4e-11 ydaH H Transporter
COCLMCBI_01447 1.5e-118 S Suppressor of fused protein (SUFU)
COCLMCBI_01448 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COCLMCBI_01449 5.1e-256 C uridylyltransferase
COCLMCBI_01450 1.5e-62
COCLMCBI_01451 2.9e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COCLMCBI_01452 3.8e-262 gdhA 1.4.1.3, 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
COCLMCBI_01453 2.6e-21 D Cell division initiation protein
COCLMCBI_01454 1.9e-95 yceD S metal-binding, possibly nucleic acid-binding protein
COCLMCBI_01455 1.9e-133 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COCLMCBI_01456 9.2e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COCLMCBI_01457 3.4e-278 agcS E alanine symporter
COCLMCBI_01458 2.2e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COCLMCBI_01459 0.0 smc D Required for chromosome condensation and partitioning
COCLMCBI_01461 3.7e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COCLMCBI_01462 3.3e-184 amt P ammonium transporter
COCLMCBI_01463 5.4e-40 glnK K nitrogen regulatory protein P-II
COCLMCBI_01464 3.2e-237 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COCLMCBI_01465 0.0 wbpC I acyltransferases
COCLMCBI_01466 6.5e-64 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COCLMCBI_01467 2.3e-219 K Transcriptional regulator
COCLMCBI_01468 6.6e-163
COCLMCBI_01469 4e-269
COCLMCBI_01470 1.1e-86 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COCLMCBI_01471 4.3e-225 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COCLMCBI_01472 2e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COCLMCBI_01473 7.4e-146 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COCLMCBI_01474 1.7e-106 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COCLMCBI_01475 1.8e-50 S Protein of unknown function (DUF2469)
COCLMCBI_01476 1.4e-65 yraN L Belongs to the UPF0102 family
COCLMCBI_01477 4.1e-281 comM O ATPase with chaperone activity
COCLMCBI_01478 5.6e-217 dprA 5.99.1.2 LU Rossmann fold nucleotide-binding protein involved in DNA uptake
COCLMCBI_01481 2.6e-155 xerC D Belongs to the 'phage' integrase family. XerC subfamily
COCLMCBI_01482 1.3e-88 M Membrane proteins related to metalloendopeptidases
COCLMCBI_01483 5.7e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
COCLMCBI_01484 1.3e-137 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COCLMCBI_01485 4.3e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COCLMCBI_01486 3.6e-139 ydcZ S protein conserved in bacteria
COCLMCBI_01487 1.6e-178 3.5.1.4 J Belongs to the amidase family
COCLMCBI_01488 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COCLMCBI_01489 1.2e-158 cdsA 2.7.7.41, 2.7.7.67 I Belongs to the CDS family
COCLMCBI_01490 6.6e-212 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COCLMCBI_01491 8.6e-55 S NADH-flavin reductase
COCLMCBI_01492 5.5e-73 pecM EG Permeases of the drug metabolite transporter DMT superfamily
COCLMCBI_01493 1.4e-92 K Transcriptional regulator
COCLMCBI_01494 2e-89 S Protein of unknown function (DUF2631)
COCLMCBI_01495 1.6e-197 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COCLMCBI_01496 1.5e-214 rseP M membrane-associated Zn-dependent proteases 1
COCLMCBI_01497 8.7e-215 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COCLMCBI_01498 0.0 pbp2B 3.4.16.4 M Cell division protein FtsI penicillin-binding protein 2
COCLMCBI_01499 1e-162 map 3.4.11.18 E Methionine aminopeptidase
COCLMCBI_01500 8.8e-21
COCLMCBI_01501 7.8e-13
COCLMCBI_01502 1.7e-10 mtr 1.8.1.15, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COCLMCBI_01503 1.7e-265 mtr 1.8.1.15, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COCLMCBI_01504 7.1e-197 I Lysophospholipase
COCLMCBI_01505 4.6e-299 mqo 1.1.5.4 C malate quinone oxidoreductase
COCLMCBI_01506 2e-214 ydiU S Uncharacterized ACR, YdiU/UPF0061 family
COCLMCBI_01507 1.9e-127 cysG 1.13.11.79, 1.3.1.76, 2.1.1.107, 4.99.1.4 H Uroporphyrinogen-III
COCLMCBI_01508 7.5e-159 rlmG 2.1.1.172, 2.1.1.174 J Methyltransferase small domain
COCLMCBI_01509 4.3e-81 3.1.31.1 L Staphylococcal nuclease homologues
COCLMCBI_01510 3.3e-124
COCLMCBI_01511 3.5e-158 K Psort location Cytoplasmic, score
COCLMCBI_01512 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COCLMCBI_01513 4e-112 yaaA S Belongs to the UPF0246 family
COCLMCBI_01514 5.1e-113
COCLMCBI_01515 5e-94 rimP S Required for maturation of 30S ribosomal subunits
COCLMCBI_01516 8.8e-179 nusA K Participates in both transcription termination and antitermination
COCLMCBI_01517 1.7e-28 ylxR K nucleic-acid-binding protein implicated in transcription termination
COCLMCBI_01518 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COCLMCBI_01519 3e-67 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COCLMCBI_01520 3.4e-135 nrnA 2.7.7.72, 3.1.13.3, 3.1.3.7 S Exopolyphosphatase-related proteins
COCLMCBI_01521 1.8e-197 dinF V Na -driven multidrug efflux pump
COCLMCBI_01522 1e-142 S serine threonine protein phosphatase
COCLMCBI_01523 6e-115 pptA Q Belongs to the P-Pant transferase superfamily
COCLMCBI_01524 4.5e-13
COCLMCBI_01525 0.0
COCLMCBI_01526 1.5e-142 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COCLMCBI_01527 3.4e-156 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COCLMCBI_01528 2.5e-167 iunH2 3.2.2.1 F nucleoside
COCLMCBI_01529 5e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COCLMCBI_01530 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
COCLMCBI_01531 3.3e-97 S PFAM Sporulation and spore germination
COCLMCBI_01532 2.9e-115 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COCLMCBI_01533 2.5e-130 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
COCLMCBI_01534 1.9e-153 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COCLMCBI_01535 0.0 rnj S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COCLMCBI_01536 2.9e-17
COCLMCBI_01537 9.8e-112 1.17.1.9, 1.7.7.2 C molybdopterin cofactor binding
COCLMCBI_01538 0.0 ftsK D DNA segregation ATPase FtsK SpoIIIE and related proteins
COCLMCBI_01539 2.6e-211 terC P Membrane protein TerC, possibly involved in tellurium resistance
COCLMCBI_01540 1.6e-39 S protein conserved in bacteria
COCLMCBI_01541 1.7e-94 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COCLMCBI_01542 1.3e-100 cinA 3.5.1.42 S Belongs to the CinA family
COCLMCBI_01543 2.9e-52 clgR K transcriptional regulators
COCLMCBI_01544 4.8e-141 pspA KT Phage shock protein A (IM30), suppresses sigma54-dependent transcription
COCLMCBI_01545 2.5e-104 bioN P Cobalt transport protein
COCLMCBI_01546 2.6e-118 bioM P ABC transporter, ATP-binding protein
COCLMCBI_01547 1e-44 bioY S BioY family
COCLMCBI_01548 9.4e-155 L HNH endonuclease domain protein
COCLMCBI_01549 7e-34 S Protein of unknown function (DUF3046)
COCLMCBI_01550 3.4e-214 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COCLMCBI_01551 2.4e-99 recX S Modulates RecA activity
COCLMCBI_01552 1.9e-150 gluB ET ABC-type amino acid transport signal transduction systems periplasmic component domain
COCLMCBI_01553 3.6e-280 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COCLMCBI_01554 3.8e-95
COCLMCBI_01556 3.1e-300 glt E Belongs to the glutamate synthase family
COCLMCBI_01557 8.3e-172 2.3.1.178, 2.3.1.57, 2.3.1.82 J Histone acetyltransferase HPA2 and related acetyltransferases
COCLMCBI_01558 1.5e-160 D Domain of Unknown Function (DUF349)
COCLMCBI_01559 1.7e-94 2.8.4.3 S ferrous iron binding
COCLMCBI_01560 5.2e-154 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COCLMCBI_01561 5.4e-151 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COCLMCBI_01562 5.9e-186 afuA P ABC transporter, solute-binding protein
COCLMCBI_01563 2.2e-191 3.6.3.29, 3.6.3.30 E ATPases associated with a variety of cellular activities
COCLMCBI_01564 9.6e-281 afuB2 P ABC transporter permease
COCLMCBI_01565 1.3e-85
COCLMCBI_01566 5.1e-123
COCLMCBI_01567 6.8e-268 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COCLMCBI_01568 1.2e-62 sugR K Transcriptional regulators of sugar metabolism
COCLMCBI_01569 3.6e-120 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COCLMCBI_01571 3.9e-73 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COCLMCBI_01572 0.0 hrpA 3.6.4.13 L ATP-dependent helicase
COCLMCBI_01573 1.3e-144 oxyR K Transcriptional regulator
COCLMCBI_01574 0.0 L DEAD DEAH box helicase
COCLMCBI_01575 1.7e-185 pac S PAC2 family
COCLMCBI_01576 2.4e-188 S Domain of unknown function (DUF4192)
COCLMCBI_01577 7.4e-175 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COCLMCBI_01578 7.9e-115 ideR K repressor
COCLMCBI_01579 2.5e-178 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COCLMCBI_01580 6.6e-67 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COCLMCBI_01581 1.2e-275 prmC_2 J Methylase of polypeptide chain release factors
COCLMCBI_01582 2.5e-69 S Protein of unknown function (DUF3099)
COCLMCBI_01583 3.1e-43 S Protein of unknown function (DUF3039)
COCLMCBI_01584 2.2e-310 sdrA L DNA or RNA helicases of superfamily II
COCLMCBI_01586 3.1e-178 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COCLMCBI_01587 3.7e-137 ppgK 2.7.1.2, 2.7.1.63 GK polyphosphate glucokinase
COCLMCBI_01588 1.5e-134 suhB 3.1.3.25 G Archaeal fructose-16-bisphosphatase and related enzymes of inositol monophosphatase family
COCLMCBI_01589 6.1e-48 S Domain of unknown function (DUF4193)
COCLMCBI_01590 4.1e-93 S Protein of unknown function (DUF3093)
COCLMCBI_01591 8.2e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
COCLMCBI_01592 1.4e-108 S Protein of unknown function (DUF3710)
COCLMCBI_01593 1.2e-214 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COCLMCBI_01594 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COCLMCBI_01595 2.9e-205 rnd 3.1.13.5 J Ribonuclease D
COCLMCBI_01596 1.3e-108 S Protein of unknown function (DUF3000)
COCLMCBI_01597 1e-133 hemH 4.99.1.1, 4.99.1.9 S Chlorite
COCLMCBI_01598 1.6e-230 aftC 2.4.2.47 S Glycosyltransferase family 87
COCLMCBI_01599 4.1e-102 ribD 1.1.1.193, 3.5.4.26 H Riboflavin biosynthesis
COCLMCBI_01607 1e-249 EGP Permeases of the major facilitator superfamily
COCLMCBI_01608 1.7e-110 copC S protein homolog of Cu resistance protein CopC
COCLMCBI_01609 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COCLMCBI_01610 7.3e-98 hit 2.7.7.53 FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
COCLMCBI_01611 5.3e-100 pgsA1 2.7.8.11, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COCLMCBI_01612 2.6e-169 htrB 2.3.1.241, 2.3.1.265 M Lauroyl myristoyl acyltransferase
COCLMCBI_01613 3.5e-189 pimA 2.4.1.345 GT4 M Glycosyltransferase
COCLMCBI_01614 5.7e-64 S LemA family
COCLMCBI_01615 9.6e-163 tesB I Acyl-CoA thioesterase
COCLMCBI_01616 1.9e-130 yebC K Transcriptional regulatory protein
COCLMCBI_01617 1.1e-95 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
COCLMCBI_01618 1e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COCLMCBI_01619 4.4e-197 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COCLMCBI_01620 1.8e-36 yajC U Preprotein translocase subunit YajC
COCLMCBI_01621 0.0 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COCLMCBI_01622 6.4e-184 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COCLMCBI_01623 2.5e-303 dciAE E ABC-type dipeptide transport system periplasmic component
COCLMCBI_01624 1.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COCLMCBI_01625 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COCLMCBI_01626 5.7e-18
COCLMCBI_01627 1.9e-119 ppiB 5.2.1.8 O Peptidyl-prolyl cis-trans isomerase
COCLMCBI_01628 1e-79 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COCLMCBI_01629 3.8e-114 ycbL 3.1.2.6 S Metallo-beta-lactamase domain protein
COCLMCBI_01630 4.9e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
COCLMCBI_01631 6.7e-61 S 5-oxoprolinase (ATP-hydrolyzing) activity
COCLMCBI_01632 5.4e-206 ugpC P Belongs to the ABC transporter superfamily
COCLMCBI_01633 8.6e-240 inaA T Domain of unknown function (DUF4032)
COCLMCBI_01634 9.3e-253 amyE G ABC transporter
COCLMCBI_01635 1.3e-146 msmF G permease
COCLMCBI_01636 6.9e-162 rafG G ABC transporter permease
COCLMCBI_01637 3.4e-96 S Psort location CytoplasmicMembrane, score
COCLMCBI_01638 3.7e-131 XK27_07850 S CBS domain
COCLMCBI_01639 9.6e-140 ypfJ S Metalloprotease
COCLMCBI_01640 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COCLMCBI_01641 1.7e-221 2.7.1.39 S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
COCLMCBI_01642 5.5e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
COCLMCBI_01643 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COCLMCBI_01644 5.8e-83 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COCLMCBI_01645 2.8e-197 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COCLMCBI_01646 4.7e-152 aroE 1.1.1.25 E Shikimate
COCLMCBI_01647 1.2e-47 pppA 3.4.23.43 NOU aspartic-type endopeptidase activity
COCLMCBI_01648 2e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COCLMCBI_01649 6.1e-109 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COCLMCBI_01650 3.6e-191 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COCLMCBI_01651 1.7e-70 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
COCLMCBI_01652 5e-196 pepQ 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
COCLMCBI_01653 2.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COCLMCBI_01654 4.9e-95 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COCLMCBI_01655 6e-157 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
COCLMCBI_01657 3.2e-62 S Putative bacterial sensory transduction regulator
COCLMCBI_01658 4.9e-74 S Putative bacterial sensory transduction regulator
COCLMCBI_01659 2.4e-240 S nucleoside-diphosphate sugar epimerase
COCLMCBI_01660 5.4e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COCLMCBI_01661 3.9e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COCLMCBI_01662 5e-232 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COCLMCBI_01663 1.4e-215 carA 6.3.5.5 F Belongs to the CarA family
COCLMCBI_01664 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthetase ammonia chain
COCLMCBI_01665 1.9e-136 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
COCLMCBI_01666 8.1e-46 mihF 2.7.4.8 J integration host factor
COCLMCBI_01667 8.9e-99 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
COCLMCBI_01668 5.1e-47 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COCLMCBI_01669 2.4e-177 L HNH endonuclease domain protein
COCLMCBI_01670 1e-65 S Protein of unknown function (DUF3558)
COCLMCBI_01671 3.9e-17 esxH S Belongs to the WXG100 family
COCLMCBI_01672 3e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COCLMCBI_01673 1.9e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COCLMCBI_01675 4.5e-117 3.5.1.104 G Polysaccharide deacetylase
COCLMCBI_01676 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COCLMCBI_01677 3.7e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COCLMCBI_01678 7.4e-172 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COCLMCBI_01679 7e-238 sun 2.1.1.176 JK Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family
COCLMCBI_01680 3.7e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COCLMCBI_01681 5.9e-125 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COCLMCBI_01682 4e-83 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
COCLMCBI_01683 1.4e-215 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COCLMCBI_01684 1.4e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COCLMCBI_01685 3.6e-97 S Bacterial PH domain
COCLMCBI_01686 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COCLMCBI_01687 1.9e-158 rapZ S Displays ATPase and GTPase activities
COCLMCBI_01688 1.1e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COCLMCBI_01689 1.7e-147 whiA K May be required for sporulation
COCLMCBI_01690 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COCLMCBI_01691 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COCLMCBI_01692 2.5e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COCLMCBI_01693 6e-30 secG U Preprotein translocase subunit SecG
COCLMCBI_01694 4.6e-129 pgl 3.1.1.31 G 6-phosphogluconolactonase
COCLMCBI_01695 6.2e-171 opcA G Glucose-6-P dehydrogenase subunit
COCLMCBI_01696 1.9e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COCLMCBI_01697 3e-193 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COCLMCBI_01698 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COCLMCBI_01699 1.8e-180 capA M Bacterial capsule synthesis protein PGA_cap
COCLMCBI_01700 9.8e-161 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
COCLMCBI_01701 2.9e-171 qor 1.6.5.5 C NADPH quinone reductase
COCLMCBI_01702 5e-177 ctaA O cytochrome oxidase assembly
COCLMCBI_01703 3.2e-125 V ABC-type multidrug transport system, permease component
COCLMCBI_01704 1.2e-142 drrA_2 V ABC transporter, ATP-binding protein
COCLMCBI_01705 3.7e-262 mptB S Carotene biosynthesis associated membrane protein
COCLMCBI_01706 3.3e-116 sufR K Transcriptional regulator
COCLMCBI_01707 1.1e-272 sufB O ABC-type transport system involved in Fe-S cluster assembly, permease component
COCLMCBI_01708 1.4e-220 sufD O ABC-type transport system involved in Fe-S cluster assembly, permease component
COCLMCBI_01709 3e-139 sufC O ABC-type transport system involved in Fe-S cluster assembly ATPase component
COCLMCBI_01710 4.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COCLMCBI_01711 6e-79 iscU C NifU homolog involved in Fe-S cluster formation
COCLMCBI_01712 4.1e-81 yitW S metal-sulfur cluster biosynthetic enzyme
COCLMCBI_01713 4.9e-272 yheS_1 S ATPase components of ABC transporters with duplicated ATPase domains
COCLMCBI_01715 1.3e-08 yheS_1 S ATPase components of ABC transporters with duplicated ATPase domains
COCLMCBI_01716 2.5e-47 S InterPro IPR014922
COCLMCBI_01718 1.3e-118 insK L Integrase core domain
COCLMCBI_01719 2.1e-41 L Transposase and inactivated derivatives
COCLMCBI_01720 3.8e-99 6.3.5.2 F glutamine amidotransferase
COCLMCBI_01721 1.5e-36
COCLMCBI_01722 8.6e-246 XK27_08635 S UPF0210 protein
COCLMCBI_01723 8.6e-41 1.1.1.3 T Belongs to the UPF0237 family
COCLMCBI_01724 3e-114 GM Nucleoside-diphosphate-sugar epimerases
COCLMCBI_01725 2.7e-133 6.3.5.2 F glutamine amidotransferase
COCLMCBI_01726 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COCLMCBI_01727 1.6e-56
COCLMCBI_01728 1.4e-179 rpfI 3.1.3.48 DM NlpC/P60 family
COCLMCBI_01729 2.3e-198 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COCLMCBI_01730 4.4e-130
COCLMCBI_01731 6e-157 trpH 3.1.3.97 S Protein of unknown function (DUF3097)
COCLMCBI_01732 2.4e-69 nfeD OU Membrane protein implicated in regulation of membrane protease activity
COCLMCBI_01733 1.6e-172 qmcA O Membrane protease subunits, stomatin prohibitin homologs
COCLMCBI_01734 2.6e-79 O sequence-specific DNA binding
COCLMCBI_01735 8.7e-103 ydjZ S SNARE-like domain protein
COCLMCBI_01737 4.5e-102 ybhB S Phospholipid-binding protein
COCLMCBI_01738 1.3e-41
COCLMCBI_01739 5.2e-190 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
COCLMCBI_01740 1.7e-193 lppL S amine dehydrogenase activity
COCLMCBI_01741 2.6e-149 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COCLMCBI_01742 1.5e-228 cysS 6.1.1.16, 6.3.1.13 J Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins
COCLMCBI_01743 1e-63
COCLMCBI_01744 9.6e-115 yniC 3.1.3.23 E phosphatase phosphohexomutase
COCLMCBI_01745 5.7e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
COCLMCBI_01746 3e-148 hisG 2.4.2.17 F ATP phosphoribosyltransferase
COCLMCBI_01747 4.5e-266 aspA 4.3.1.1 E Aspartate ammonia-lyase
COCLMCBI_01748 2.4e-213 dcuB S C4-dicarboxylate
COCLMCBI_01749 6.7e-309 fhs 6.3.4.3 H Belongs to the formate--tetrahydrofolate ligase family
COCLMCBI_01750 3.4e-157 recB L RecB family exonuclease
COCLMCBI_01751 9e-220 apeB 3.4.11.21 E M18 family aminopeptidase
COCLMCBI_01752 4.2e-163 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
COCLMCBI_01753 9.9e-272 arc O AAA ATPase forming ring-shaped complexes
COCLMCBI_01754 2.1e-20 mazF3 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COCLMCBI_01756 7.4e-229 pdxR K HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COCLMCBI_01757 4.6e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
COCLMCBI_01758 4.9e-279 dop 3.5.1.119, 6.3.1.19 S accessory factor
COCLMCBI_01759 1.7e-24 pup O Pup-like protein
COCLMCBI_01760 4e-262 pafA 6.3.1.19 H Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
COCLMCBI_01761 5.3e-170 K Transcriptional regulator
COCLMCBI_01762 1.3e-165 pafC K Transcriptional regulator
COCLMCBI_01763 2.7e-32 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
COCLMCBI_01764 2.7e-153 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides
COCLMCBI_01765 0.0 helY L DEAD DEAH box helicase
COCLMCBI_01766 5.7e-71 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COCLMCBI_01767 1.8e-204 pepE 3.4.13.9 E Peptidase M24
COCLMCBI_01768 2.2e-123 MA20_24385 S Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
COCLMCBI_01769 4.5e-252 3.1.1.3 S Secretory lipase
COCLMCBI_01770 3.9e-82 fxsA 2.3.3.13 S Protein affecting phage T7 exclusion by the F plasmid
COCLMCBI_01771 2.3e-295 lnt GT2 M Transfers the fatty acyl group on membrane lipoproteins
COCLMCBI_01772 3.3e-170 ppm1 2.4.1.83 GT2 M Glycosyltransferases involved in cell wall biogenesis
COCLMCBI_01773 1.4e-47 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
COCLMCBI_01774 8.3e-46
COCLMCBI_01775 2.2e-117 S Belongs to the UPF0312 family
COCLMCBI_01776 3.7e-197 cfa 2.1.1.317, 2.1.1.79 M Cyclopropane fatty acid synthase and related methyltransferases
COCLMCBI_01777 1.1e-261 ndh 1.6.99.3 C NADH dehydrogenase
COCLMCBI_01778 2.6e-189 corA P Magnesium transport protein CorA
COCLMCBI_01779 3.1e-72 ydiI Q protein possibly involved in aromatic compounds catabolism
COCLMCBI_01780 5.2e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COCLMCBI_01781 1e-218 deaD 3.6.4.13 L Superfamily II DNA and RNA helicases
COCLMCBI_01782 9.6e-229 tlyC S Hemolysins and related proteins containing CBS domains
COCLMCBI_01783 5.1e-182 ytfL S Hemolysins and related proteins containing CBS domains
COCLMCBI_01784 6.8e-148 S 3-methyladenine DNA glycosylase
COCLMCBI_01785 4.4e-189 S von Willebrand factor (vWF) type A domain
COCLMCBI_01786 7.3e-98 merR2 K transcriptional
COCLMCBI_01787 3.3e-101 S Bifunctional nuclease
COCLMCBI_01788 2.3e-103 merR1 K transcriptional
COCLMCBI_01789 2.8e-70 odhI T Oxoglutarate dehydrogenase inhibitor
COCLMCBI_01790 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COCLMCBI_01792 2e-195 ybdR 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COCLMCBI_01793 5.7e-56 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COCLMCBI_01794 9e-154 CE1 Q Poly(3-hydroxybutyrate) depolymerase
COCLMCBI_01795 2.8e-132 Q SAM-dependent
COCLMCBI_01796 2e-278 V HNH endonuclease domain protein
COCLMCBI_01797 2e-93 CE1 Q xylan catabolic process
COCLMCBI_01798 9.8e-132 CE1 Q Phospholipase/Carboxylesterase
COCLMCBI_01799 1.6e-258 der 1.1.1.399, 1.1.1.95 F GTPase that plays an essential role in the late steps of ribosome biogenesis
COCLMCBI_01800 1.2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COCLMCBI_01801 3.3e-159 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COCLMCBI_01802 1.6e-86 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COCLMCBI_01803 5.1e-145 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COCLMCBI_01804 4.3e-158 soj D ATPases involved in chromosome partitioning
COCLMCBI_01805 8.1e-152 xerD D recombinase XerD
COCLMCBI_01806 2.2e-106 nudF 3.6.1.13 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_01807 3.1e-133 mctB S Copper transport outer membrane protein, MctB
COCLMCBI_01808 6.3e-208 S membrane-anchored protein conserved in bacteria
COCLMCBI_01809 4.8e-233 recN L May be involved in recombinational repair of damaged DNA
COCLMCBI_01810 1.5e-175 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COCLMCBI_01811 5e-148 tlyA 2.1.1.226, 2.1.1.227 J ribosomal RNA large subunit methyltransferase J
COCLMCBI_01813 3e-171 yutF 3.1.3.41 G sugar phosphatases of the HAD superfamily
COCLMCBI_01814 3.3e-136 J pseudouridine synthase activity
COCLMCBI_01815 3.7e-235 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COCLMCBI_01816 6.6e-30 S Trm112p-like protein
COCLMCBI_01817 3.1e-100
COCLMCBI_01818 9.2e-268 P protein containing a von Willebrand factor type A (vWA) domain
COCLMCBI_01819 4.9e-210 P Sulfate ABC transporter periplasmic sulfate-binding protein
COCLMCBI_01820 1.6e-255 argH 4.3.2.1 E argininosuccinate lyase
COCLMCBI_01821 1.4e-226 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COCLMCBI_01822 5.9e-83 argR K Regulates arginine biosynthesis genes
COCLMCBI_01823 2.4e-162 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COCLMCBI_01824 1.6e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
COCLMCBI_01825 1e-173 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
COCLMCBI_01826 1.8e-199 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COCLMCBI_01827 3.9e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COCLMCBI_01828 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COCLMCBI_01829 1.2e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COCLMCBI_01830 2.2e-132 tsnR 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCLMCBI_01831 2.4e-193
COCLMCBI_01832 1e-168 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_01833 6.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COCLMCBI_01834 8.2e-25 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COCLMCBI_01835 1.7e-54 infC J binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COCLMCBI_01836 1.2e-178 S Predicted membrane protein (DUF2339)
COCLMCBI_01837 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COCLMCBI_01838 1.3e-110 S Zn-dependent hydrolases including glyoxylases
COCLMCBI_01839 1.8e-84 doxX S DoxX family
COCLMCBI_01840 0.0 helD L Superfamily I DNA and RNA helicases
COCLMCBI_01841 4.5e-71 uspA3 T universal stress protein
COCLMCBI_01842 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COCLMCBI_01843 4.8e-93 S SBF-like CPA transporter family (DUF4137)
COCLMCBI_01844 2.8e-101 K BetI-type transcriptional repressor, C-terminal
COCLMCBI_01845 5e-258 E Bacterial extracellular solute-binding proteins, family 5 Middle
COCLMCBI_01846 4.1e-154 P ABC transporter permease
COCLMCBI_01847 9e-126 P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COCLMCBI_01848 1.8e-264 P Belongs to the ABC transporter superfamily
COCLMCBI_01849 1.1e-237 2.3.1.21, 2.3.1.7 S Choline/Carnitine o-acyltransferase
COCLMCBI_01850 1.8e-51 S Domain of unknown function (DUF4259)
COCLMCBI_01851 1.5e-69 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COCLMCBI_01852 1.7e-223 rpsA J Ribosomal protein S1
COCLMCBI_01853 7.7e-95 Q SAM-dependent methyltransferases
COCLMCBI_01854 2.8e-166 S Membrane
COCLMCBI_01855 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COCLMCBI_01858 1.4e-53
COCLMCBI_01859 2.2e-130 S EamA-like transporter family
COCLMCBI_01860 1.2e-77 M Protein of unknown function (DUF1541)
COCLMCBI_01861 5.3e-184 G transmembrane transporter activity
COCLMCBI_01862 5.4e-228 S Metal-dependent amidase aminoacylase carboxypeptidase
COCLMCBI_01863 3.4e-283 alsT E Amino acid carrier protein
COCLMCBI_01864 1.6e-96 E GDSL-like Lipase/Acylhydrolase family
COCLMCBI_01865 7.7e-69
COCLMCBI_01866 1.9e-119 phr 4.1.99.3 L Belongs to the DNA photolyase family
COCLMCBI_01867 1.6e-146 3.1.1.74 S Cutinase
COCLMCBI_01868 6.9e-30
COCLMCBI_01869 3e-162 pknD ET ABC-type amino acid transport signal transduction systems periplasmic component domain
COCLMCBI_01870 4.8e-152 yecS P ABC-type amino acid transport system permease component
COCLMCBI_01871 1.1e-133 atrC 3.6.3.21 E ABC transporter, ATP-binding protein
COCLMCBI_01872 9e-50 L Transposase and inactivated derivatives
COCLMCBI_01873 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_01875 5.9e-69 L Integrase core domain
COCLMCBI_01876 9.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COCLMCBI_01877 3.2e-101 rsmD 2.1.1.171 L DNA methylase
COCLMCBI_01878 0.0 recG 3.6.4.12 L ATP-dependent DNA helicase
COCLMCBI_01879 5.7e-238 dak3 2.7.1.28, 2.7.1.29, 4.6.1.15 S kinase related to dihydroxyacetone kinase
COCLMCBI_01880 9.3e-118 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COCLMCBI_01881 2.3e-160 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
COCLMCBI_01882 2.3e-130 S Protein of unknown function (DUF3515)
COCLMCBI_01883 1.3e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COCLMCBI_01884 6.4e-174 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COCLMCBI_01885 4.2e-189 mutT 3.6.1.55, 5.4.2.12 FG Belongs to the Nudix hydrolase family
COCLMCBI_01886 9.5e-109 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COCLMCBI_01887 3.3e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COCLMCBI_01888 2.4e-111 ltbR K Transcriptional regulator
COCLMCBI_01889 0.0 4.1.1.20 E Diaminopimelate decarboxylase
COCLMCBI_01890 2.9e-168 cysM 2.5.1.140 E Cysteine synthase
COCLMCBI_01891 3.4e-65 pcaC 4.1.1.44 S homolog of gamma-carboxymuconolactone decarboxylase subunit
COCLMCBI_01892 6e-94 S response to pH
COCLMCBI_01893 3.4e-80 S response to pH
COCLMCBI_01894 5.4e-93
COCLMCBI_01895 7e-58 L Helix-turn-helix domain
COCLMCBI_01896 1.4e-134 insK L Transposase and inactivated derivatives
COCLMCBI_01898 1e-168 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_01902 1.2e-208 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_01903 3.6e-178 2.7.7.7 L Transposase and inactivated derivatives
COCLMCBI_01904 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_01905 9e-50 L Transposase and inactivated derivatives
COCLMCBI_01906 4.3e-118 L COG4584 Transposase and inactivated derivatives
COCLMCBI_01907 1.4e-134 L DNA replication protein
COCLMCBI_01910 1.8e-262 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COCLMCBI_01911 3e-105 lpqC CE1 Q Poly(3-hydroxybutyrate) depolymerase
COCLMCBI_01912 1.7e-218 menF 5.4.4.2 HQ Isochorismate synthase
COCLMCBI_01913 7.7e-138 odx Q 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-17-dioic acid hydratase (catechol pathway)
COCLMCBI_01914 9.7e-98 dnaQ3 2.7.7.7 L DNA polymerase III
COCLMCBI_01915 0.0 VP1725 T signal-transduction protein containing cAMP-binding and CBS domains
COCLMCBI_01916 4.5e-232 2.8.1.7, 4.4.1.16 S domain, Protein
COCLMCBI_01917 2.3e-171 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
COCLMCBI_01918 3.8e-94 nrp GM NAD(P)H-binding
COCLMCBI_01919 8.1e-272 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COCLMCBI_01920 1.1e-135
COCLMCBI_01921 0.0 S Protein of unknown function DUF262
COCLMCBI_01922 3.1e-132 czcD P Co Zn Cd efflux system component
COCLMCBI_01924 4.3e-200 L Transposase and inactivated derivatives IS30 family
COCLMCBI_01926 2.2e-190 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COCLMCBI_01927 1.9e-84 ilvN 2.2.1.6 E Acetolactate synthase small
COCLMCBI_01928 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase
COCLMCBI_01929 8.5e-215 mscS M Transporter, small conductance mechanosensitive ion channel MscS family protein
COCLMCBI_01930 1.1e-81 cfp6 S Bacterial PH domain
COCLMCBI_01931 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
COCLMCBI_01932 3.5e-217 GT87 S Pfam:DUF2029
COCLMCBI_01933 9e-57 mhqP S membrane
COCLMCBI_01934 2.4e-187 yghZ C oxidoreductases (related to
COCLMCBI_01935 8e-239 S Membrane
COCLMCBI_01936 3.7e-274 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCLMCBI_01937 8.8e-128 yocS S Na -dependent transporter
COCLMCBI_01938 2e-115 nadC 2.4.2.19 H Belongs to the NadC ModD family
COCLMCBI_01939 3.9e-83 J Acetyltransferases, including N-acetylases of ribosomal proteins
COCLMCBI_01940 3.4e-121 galE1 4.2.1.46, 5.1.3.2 M 4-epimerase
COCLMCBI_01941 8.3e-185 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COCLMCBI_01942 4.5e-212 emrB EGP the major facilitator superfamily
COCLMCBI_01943 1.7e-263 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COCLMCBI_01944 3.5e-43 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COCLMCBI_01945 3.1e-116 2.7.6.5, 3.1.7.2 KT ACT domain protein
COCLMCBI_01947 2.3e-147 V Beta-lactamase class C and other penicillin binding proteins
COCLMCBI_01948 2.3e-53 K Helix-turn-helix domain
COCLMCBI_01950 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COCLMCBI_01951 2.7e-132 tipA K transcriptional regulators
COCLMCBI_01952 5e-122 dnaQ2 2.7.7.7 L DNA polymerase III
COCLMCBI_01954 1.4e-153 2.1.1.14 E Methionine synthase
COCLMCBI_01956 6e-202 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COCLMCBI_01957 3e-180 T Histidine kinase
COCLMCBI_01958 8.7e-114 K Response regulator receiver domain protein
COCLMCBI_01959 4.4e-107 clvF V ABC transporter, ATP-binding protein
COCLMCBI_01960 9e-50 L Transposase and inactivated derivatives
COCLMCBI_01961 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_01962 5.2e-42 clvF V ABC transporter, ATP-binding protein
COCLMCBI_01963 5.4e-109 S ABC-2 family transporter protein
COCLMCBI_01964 1.5e-119 S ABC-2 family transporter protein
COCLMCBI_01965 9.6e-149 speE 2.5.1.16 E Spermidine synthase
COCLMCBI_01966 2.5e-200 acm_1 M Lyzozyme M1 (1,4-beta-N-acetylmuramidase)
COCLMCBI_01967 4.1e-171 iscS 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
COCLMCBI_01968 4.1e-162 etfA C Electron transfer flavoprotein
COCLMCBI_01969 4.4e-130 etfB 1.3.1.108 C Electron transfer flavoprotein
COCLMCBI_01970 1.3e-197 J SAM-dependent methyltransferases
COCLMCBI_01971 3.4e-157 MA20_36340 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_01972 9.7e-155 modF 3.6.3.21, 3.6.3.34 P ABC-type molybdenum transport system ATPase component photorepair protein PhrA
COCLMCBI_01973 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
COCLMCBI_01974 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COCLMCBI_01975 3e-46 S Thiamine-binding protein
COCLMCBI_01976 6.3e-128 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
COCLMCBI_01977 7.2e-72 S Protein of unknown function (DUF2550)
COCLMCBI_01978 4.8e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COCLMCBI_01979 3.5e-280 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COCLMCBI_01980 2e-156 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COCLMCBI_01981 2.3e-301 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COCLMCBI_01982 4.3e-139 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCLMCBI_01983 1e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COCLMCBI_01984 2.6e-33 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COCLMCBI_01985 8.2e-132 atpB C it plays a direct role in the translocation of protons across the membrane
COCLMCBI_01986 3.1e-67 atpI
COCLMCBI_01987 7.8e-88
COCLMCBI_01988 2.3e-201 S Membrane
COCLMCBI_01989 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
COCLMCBI_01990 4.6e-192 tagO 2.7.8.33, 2.7.8.35 M UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
COCLMCBI_01991 7.1e-121 ywlC 2.7.7.87 J Belongs to the SUA5 family
COCLMCBI_01992 6e-158 prmC 2.1.1.297, 2.6.1.85 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COCLMCBI_01993 2.1e-162 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COCLMCBI_01994 2.6e-216 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COCLMCBI_01995 0.0 fadD4 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_01996 2.2e-210 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
COCLMCBI_01997 3.5e-166 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COCLMCBI_01998 1.7e-238 hom 1.1.1.3 E homoserine dehydrogenase
COCLMCBI_01999 6.9e-259 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COCLMCBI_02000 1.9e-308 argS 6.1.1.19 J Arginyl-tRNA synthetase
COCLMCBI_02001 3.9e-299 lldT C permease
COCLMCBI_02002 1.5e-146 lutA C Fe-S oxidoreductase
COCLMCBI_02003 3.6e-296 lutB C conserved protein containing a ferredoxin-like domain
COCLMCBI_02004 1.4e-100 lutC S conserved protein containing a ferredoxin-like domain
COCLMCBI_02005 2e-278 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COCLMCBI_02006 1.3e-122 S DJ-1/PfpI family
COCLMCBI_02007 3.3e-106
COCLMCBI_02008 7.1e-95 S CAAX amino terminal protease
COCLMCBI_02009 1.7e-12
COCLMCBI_02010 2.6e-89 yceI S Belongs to the UPF0312 family
COCLMCBI_02012 8.5e-60 cmtR K transcriptional
COCLMCBI_02013 9.7e-85 cadD P Pfam PF03596
COCLMCBI_02014 6.7e-66
COCLMCBI_02016 5.8e-61
COCLMCBI_02017 1.3e-163 S Endonuclease/Exonuclease/phosphatase family
COCLMCBI_02018 3.6e-29 pspC KT PspC domain protein
COCLMCBI_02019 9.4e-73 rosR K Transcriptional regulator, MarR family
COCLMCBI_02020 0.0 sbcC L DNA repair
COCLMCBI_02021 1.4e-207 sbcD L DNA repair exonuclease
COCLMCBI_02022 1.6e-149 S zinc finger
COCLMCBI_02023 0.0 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02024 3.4e-278 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COCLMCBI_02025 1.4e-121 L HNH endonuclease
COCLMCBI_02026 2.1e-77
COCLMCBI_02027 2.9e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation
COCLMCBI_02028 2.9e-84 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COCLMCBI_02029 8.4e-106 rhtC E threonine efflux protein
COCLMCBI_02031 3.3e-55
COCLMCBI_02033 3.2e-08
COCLMCBI_02034 9e-50 L Transposase and inactivated derivatives
COCLMCBI_02035 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_02036 6.3e-247 L Transposase and inactivated derivatives
COCLMCBI_02038 1.8e-86 L Phage integrase family
COCLMCBI_02039 7.6e-13 6.3.5.2 F glutamine amidotransferase
COCLMCBI_02040 3.9e-89 mae1 P Tellurite resistance protein and related permeases
COCLMCBI_02041 2.6e-86 K LysR substrate binding domain
COCLMCBI_02042 1.8e-199 lppS S protein conserved in bacteria
COCLMCBI_02044 1.1e-90 pncA 2.7.11.1, 3.5.1.19 Q Amidases related to nicotinamidase
COCLMCBI_02045 2.4e-25 S Protein of unknown function (DUF3618)
COCLMCBI_02046 8.8e-81 bcp 1.11.1.15 O bacterioferritin comigratory protein
COCLMCBI_02048 6e-60 lprD V PFAM secretion protein HlyD family protein
COCLMCBI_02049 4e-55 S Domain of unknown function (DUF3817)
COCLMCBI_02050 3.6e-61
COCLMCBI_02051 1.6e-95 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COCLMCBI_02052 3.7e-131 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
COCLMCBI_02053 9.1e-144 yhfI S Metal-dependent hydrolases of the beta-lactamase superfamily III
COCLMCBI_02054 3.9e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COCLMCBI_02055 9.2e-87 K transcriptional
COCLMCBI_02056 2.5e-109 SEN0012 S membrane protein (homolog of Drosophila rhomboid)
COCLMCBI_02057 1.3e-155 dmpA 3.4.11.19 EQ L-aminopeptidase D-esterase
COCLMCBI_02058 2.5e-92 S Domain of unknown function (DUF2017)
COCLMCBI_02059 1.8e-56 clpS S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
COCLMCBI_02060 1.6e-241 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COCLMCBI_02061 0.0 dinG 2.7.7.7, 3.6.4.12 L Rad3-related DNA helicases
COCLMCBI_02062 1.7e-121 pth_2 3.1.1.29 S peptidyl-tRNA hydrolase, PTH2
COCLMCBI_02063 6.5e-208 serB 3.1.3.3 ET phosphoserine phosphatase
COCLMCBI_02064 0.0 ctaD 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COCLMCBI_02065 4.7e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCLMCBI_02066 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COCLMCBI_02067 8.3e-88 nrdI F Probably involved in ribonucleotide reductase function
COCLMCBI_02068 1.6e-35 nrdH O Glutaredoxin
COCLMCBI_02069 9.1e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COCLMCBI_02070 3.1e-227 EGP Major facilitator Superfamily
COCLMCBI_02071 5.9e-152 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COCLMCBI_02072 1.2e-25
COCLMCBI_02073 2.2e-55 S Antitoxin component of a toxin-antitoxin (TA) module
COCLMCBI_02074 8.2e-137 G Fructosamine kinase
COCLMCBI_02075 4.2e-67 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COCLMCBI_02076 1e-185 3.6.3.29, 3.6.3.30 E ATPases associated with a variety of cellular activities
COCLMCBI_02077 2e-278 afuB2 P ABC transporter permease
COCLMCBI_02078 4.3e-181 afuA P ABC transporter, solute-binding protein
COCLMCBI_02081 3e-78 pknE 2.7.11.1 O Protein-disulfide isomerase
COCLMCBI_02082 9.1e-52 S DoxX family
COCLMCBI_02083 1.4e-146 S AAA ATPase domain
COCLMCBI_02084 0.0 pgm 5.4.2.2 G Phosphoglucomutase
COCLMCBI_02085 2.4e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCLMCBI_02086 5.7e-71 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COCLMCBI_02087 0.0 Q ABC-type antimicrobial peptide transport system, permease component
COCLMCBI_02088 1.4e-139 V ABC-type antimicrobial peptide transport system, ATPase component
COCLMCBI_02090 9.6e-13
COCLMCBI_02091 1.5e-198 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COCLMCBI_02092 6.2e-146 ramA K transcriptional regulator (LuxR family)
COCLMCBI_02093 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COCLMCBI_02094 2.4e-75 cysE 2.3.1.30 E serine acetyltransferase
COCLMCBI_02095 2.9e-42 S acetyltransferase
COCLMCBI_02100 2.9e-60 S Protein of unknown function (DUF1345)
COCLMCBI_02101 5.4e-66 yccF S membrane
COCLMCBI_02102 2.5e-125 zupT P Mediates zinc uptake. May also transport other divalent cations
COCLMCBI_02103 4.8e-105 G Trehalose synthase
COCLMCBI_02104 0.0 fadD7 6.2.1.3 IQ Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COCLMCBI_02105 1.3e-101 ubiA 2.5.1.133, 2.5.1.62 H COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
COCLMCBI_02106 1.1e-40 crtYf H lycopene cyclase domain
COCLMCBI_02107 1.6e-48 crtYe S lycopene cyclase
COCLMCBI_02108 7.8e-288 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31, 1.3.99.37 Q Phytoene dehydrogenase and related proteins
COCLMCBI_02109 1.6e-149 crtB 2.5.1.21, 2.5.1.32, 2.5.1.96, 2.5.1.99 I phytoene squalene synthetase
COCLMCBI_02110 4.8e-110 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COCLMCBI_02112 2.8e-282 scpC 2.8.3.18, 3.1.2.1 C succinate CoA transferase
COCLMCBI_02113 5.5e-217 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COCLMCBI_02114 4e-128 phoU P Plays a role in the regulation of phosphate uptake
COCLMCBI_02115 2.6e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COCLMCBI_02116 1.7e-153 pstA P phosphate transport system permease
COCLMCBI_02117 1e-177 pstC P probably responsible for the translocation of the substrate across the membrane
COCLMCBI_02118 1.1e-174 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
COCLMCBI_02119 4.5e-153 mshD 2.3.1.189, 2.7.4.1 K Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol
COCLMCBI_02120 2.8e-124 S Protein of unknown function (DUF2993)
COCLMCBI_02121 1.1e-124 S May play a role in the intracellular transport of hydrophobic ligands
COCLMCBI_02122 5.7e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
COCLMCBI_02123 2.7e-200 ygfZ 2.1.2.10 S Belongs to the GcvT family
COCLMCBI_02124 1e-31 S Protein of unknown function (DUF3073)
COCLMCBI_02125 2.1e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COCLMCBI_02126 2.3e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COCLMCBI_02127 4e-60 I Sterol carrier protein
COCLMCBI_02128 5.4e-189 3.1.2.20, 3.1.2.23 I Acyl-CoA hydrolase
COCLMCBI_02130 1.2e-80 S Region found in RelA / SpoT proteins
COCLMCBI_02131 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCLMCBI_02132 2.9e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCLMCBI_02133 1.1e-31 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COCLMCBI_02134 1.7e-111 P ABC-type metal ion transport system periplasmic component surface adhesin
COCLMCBI_02135 6e-107 fhuC P ATP-binding protein
COCLMCBI_02136 6e-117 znuB P ABC-type Mn2 Zn2 transport systems permease components
COCLMCBI_02137 9.3e-124 S deacetylase
COCLMCBI_02138 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
COCLMCBI_02139 9.9e-163 purC 6.3.2.6, 6.3.4.13 F Belongs to the SAICAR synthetase family
COCLMCBI_02140 2.5e-16
COCLMCBI_02141 3.7e-263 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COCLMCBI_02142 3e-210 purD 6.3.4.13 F Belongs to the GARS family
COCLMCBI_02143 1.5e-69 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
COCLMCBI_02144 3.7e-247 phoR 2.7.13.3 T Histidine kinase
COCLMCBI_02145 1.2e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COCLMCBI_02146 3.4e-200 L HNH endonuclease domain protein
COCLMCBI_02148 3.2e-255 thrE S Amino acid export carrier protein
COCLMCBI_02149 1.3e-28
COCLMCBI_02150 5.2e-248 otsA 2.4.1.15, 2.4.1.347, 3.1.3.12 GT20 G synthase
COCLMCBI_02151 4.5e-66 O response to heat
COCLMCBI_02152 6.9e-126 otsB 2.4.1.15, 2.4.1.347, 3.1.3.12 GT20 G Removes the phosphate from trehalose 6-phosphate to produce free trehalose
COCLMCBI_02153 6.2e-186 lacI K Transcriptional regulator, LacI family
COCLMCBI_02154 2e-158 CE1 Q depolymerase
COCLMCBI_02155 2.3e-173 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COCLMCBI_02156 1.4e-270 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
COCLMCBI_02157 1.4e-81 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
COCLMCBI_02158 1.2e-124 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
COCLMCBI_02159 5.4e-96 carD K to M. xanthus CarD
COCLMCBI_02160 4.1e-80 lpqE S Copper chaperone PCu(A)C
COCLMCBI_02161 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COCLMCBI_02162 9.3e-184 disA 2.7.7.85 L DNA integrity scanning protein DisA
COCLMCBI_02163 6.1e-86
COCLMCBI_02164 9.3e-99 cah 4.2.1.1 P Reversible hydration of carbon dioxide
COCLMCBI_02165 2.6e-155 mutY L A G-specific
COCLMCBI_02166 0.0
COCLMCBI_02167 1.8e-23 S Protein of unknown function (DUF4236)
COCLMCBI_02168 0.0 clpC O ATPases with chaperone activity, ATP-binding subunit
COCLMCBI_02169 1.9e-36
COCLMCBI_02171 7.8e-41 T ATPase activity
COCLMCBI_02172 1.7e-95 KLT serine threonine protein kinase
COCLMCBI_02173 1.1e-65 S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COCLMCBI_02174 3e-40
COCLMCBI_02175 3.9e-52 S TM2 domain protein
COCLMCBI_02176 8.2e-19 J TM2 domain
COCLMCBI_02177 3.5e-79
COCLMCBI_02178 8.5e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COCLMCBI_02179 1e-127 S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
COCLMCBI_02180 3.1e-131 panC 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
COCLMCBI_02181 2.2e-120 S nadp oxidoreductase, coenzyme f420-dependent
COCLMCBI_02182 1.3e-70
COCLMCBI_02183 2.4e-75 S Protein of unknown function (DUF3180)
COCLMCBI_02184 1.4e-75 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
COCLMCBI_02185 2.1e-68 folB 1.13.11.81, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COCLMCBI_02186 6.8e-159 folP 2.5.1.15 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COCLMCBI_02187 2.1e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
COCLMCBI_02188 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COCLMCBI_02189 8.2e-114 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COCLMCBI_02193 1e-128 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COCLMCBI_02194 2.7e-217 dacB 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
COCLMCBI_02195 5e-115 M isomerase activity
COCLMCBI_02196 8.2e-87 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
COCLMCBI_02197 1.3e-85
COCLMCBI_02198 3.7e-112 ylcC 3.4.22.70 M Sortase (surface protein transpeptidase)
COCLMCBI_02199 1.3e-42 glpE P Sulfurtransferase
COCLMCBI_02200 4.1e-73 marR1 K transcriptional
COCLMCBI_02201 6e-111 echA6 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
COCLMCBI_02202 1.6e-182 ppk2 2.7.4.1 S polyphosphate kinase
COCLMCBI_02205 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COCLMCBI_02206 1.1e-266 V endonuclease
COCLMCBI_02207 4e-252 tpdA E desuccinylase and related deacylases
COCLMCBI_02208 1e-90 E Belongs to the alpha-IPM synthase homocitrate synthase family
COCLMCBI_02209 0.0 mrpA 1.6.5.3 CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit
COCLMCBI_02210 1.7e-79 phaC 1.6.5.3 P H antiporter
COCLMCBI_02211 0.0 mrpD CP Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit
COCLMCBI_02212 7.1e-84 mrpE P H antiporter
COCLMCBI_02213 4.7e-42 mrpF P monovalent cation H antiporter subunit F
COCLMCBI_02214 1.2e-58 mrpG P Subunit G of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COCLMCBI_02215 5.8e-153 D Protein of unknown function (DUF3375)
COCLMCBI_02216 1.2e-80 S Domain of unknown function (DUF4194)
COCLMCBI_02217 0.0 S Putative exonuclease SbcCD, C subunit
COCLMCBI_02218 9.6e-110 S Uncharacterized protein conserved in bacteria N-term (DUF3322)
COCLMCBI_02219 1.1e-222 ybdK H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
COCLMCBI_02220 3.2e-55 S LytR cell envelope-related transcriptional attenuator
COCLMCBI_02221 1e-28 S Protein of unknown function (DUF3263)
COCLMCBI_02222 2.3e-110 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COCLMCBI_02223 4.2e-173 yobR 2.3.1.1 K Acetyltransferase
COCLMCBI_02224 1.2e-146 xthA 3.1.11.2, 6.5.1.1 L exodeoxyribonuclease III
COCLMCBI_02225 0.0 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COCLMCBI_02226 5.6e-39 K Psort location Cytoplasmic, score
COCLMCBI_02227 2.8e-121 sagI S ABC-2 family transporter protein
COCLMCBI_02228 8.6e-155 drrA_3 V ABC transporter, ATP-binding protein
COCLMCBI_02229 5.9e-82 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
COCLMCBI_02230 1.5e-227 4.6.1.1 T phosphoserine phosphatase activity
COCLMCBI_02231 2.7e-156 glnH ET ABC-type amino acid transport signal transduction systems periplasmic component domain
COCLMCBI_02232 0.0 KLT serine threonine protein kinase
COCLMCBI_02233 8.6e-81
COCLMCBI_02234 2.3e-100 spoIVA S Conserved hypothetical ATP binding protein
COCLMCBI_02235 7.5e-59 T response regulator
COCLMCBI_02236 4.2e-212 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COCLMCBI_02237 4e-235 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COCLMCBI_02238 1.2e-263 fprA 1.18.1.2, 1.19.1.1 E NADPH-dependent glutamate synthase beta chain and related oxidoreductases
COCLMCBI_02239 3.8e-51
COCLMCBI_02240 1.6e-49 fprA 1.18.1.2, 1.19.1.1 E NADPH-dependent glutamate synthase beta chain and related oxidoreductases
COCLMCBI_02241 3.5e-28 fprA 1.18.1.2, 1.19.1.1 E NADPH-dependent glutamate synthase beta chain and related oxidoreductases
COCLMCBI_02242 2.6e-26 K Helix-turn-helix domain
COCLMCBI_02243 5.8e-34
COCLMCBI_02244 3.6e-152
COCLMCBI_02245 5.4e-14 K cell wall organization
COCLMCBI_02247 4.7e-119 ylcC 3.4.22.70 M Sortase family
COCLMCBI_02248 1.6e-82 D CobQ CobB MinD ParA nucleotide binding domain
COCLMCBI_02250 6.3e-18 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COCLMCBI_02252 5.6e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COCLMCBI_02253 1.2e-136 I lipid kinase activity
COCLMCBI_02254 2.3e-111 puhA S protein conserved in bacteria
COCLMCBI_02255 7.8e-220 S membrane
COCLMCBI_02256 1.2e-191 fbaA 4.1.2.13 G aldolase
COCLMCBI_02257 3.4e-219 G hydrolase
COCLMCBI_02258 3.5e-113 spoU 2.1.1.185 J RNA methyltransferase
COCLMCBI_02259 3.6e-106 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COCLMCBI_02260 2.1e-109
COCLMCBI_02261 4.3e-155 sseB 2.8.1.1, 2.8.1.2 P Rhodanese-related sulfurtransferase
COCLMCBI_02262 4e-66 S Domain of unknown function (DUF4265)
COCLMCBI_02263 1.6e-38 K Psort location Cytoplasmic, score
COCLMCBI_02264 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COCLMCBI_02265 3e-68 yobV3 K regulation of single-species biofilm formation
COCLMCBI_02266 1.9e-248 gltT E glutamate symporter
COCLMCBI_02267 2.8e-128 1.16.1.3, 1.5.1.41 C 2 iron, 2 sulfur cluster binding
COCLMCBI_02268 7.4e-141 S amidohydrolase
COCLMCBI_02270 2.4e-180 S Alpha/beta hydrolase
COCLMCBI_02271 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COCLMCBI_02272 2.5e-46 D nuclear chromosome segregation
COCLMCBI_02273 1.1e-63 hspR K transcriptional
COCLMCBI_02274 8.8e-170 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COCLMCBI_02275 5.1e-96 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COCLMCBI_02276 0.0 dnaK O Heat shock 70 kDa protein
COCLMCBI_02278 1.8e-87 pfpI 3.5.1.124 S Intracellular protease
COCLMCBI_02279 2.3e-190 lplA 6.3.1.20 H lipoate-protein ligase A
COCLMCBI_02280 1.5e-113 S Golgi phosphoprotein 3 (GPP34)
COCLMCBI_02281 1.1e-78 slyA K Winged helix DNA-binding domain
COCLMCBI_02282 1e-48
COCLMCBI_02283 2e-119 ribB 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COCLMCBI_02284 2.6e-173 2.3.1.51 I Phosphate acyltransferases
COCLMCBI_02285 0.0 S MMPL family
COCLMCBI_02286 8.8e-98 S Golgi phosphoprotein 3 (GPP34)
COCLMCBI_02287 1.3e-155 ytnM S membrane transporter protein
COCLMCBI_02288 2.1e-110 cbiX S sirohydrochlorin cobaltochelatase
COCLMCBI_02289 1.4e-221 cysN 2.7.1.25, 2.7.7.4 H Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
COCLMCBI_02290 1e-170 cysD 1.8.4.10, 1.8.4.8, 2.7.7.4 H 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
COCLMCBI_02291 2.9e-134 cysH 1.8.4.10, 1.8.4.8 EH Reduction of activated sulfate into sulfite
COCLMCBI_02292 1.4e-45
COCLMCBI_02293 2e-308 sir 1.7.7.1, 1.8.7.1 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
COCLMCBI_02294 7.8e-80 1.18.1.2, 1.19.1.1 E 'glutamate synthase
COCLMCBI_02295 5.9e-70 vapC S ribonuclease activity
COCLMCBI_02297 3.5e-289 ycfI V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_02298 0.0 V ABC-type multidrug transport system, ATPase and permease components
COCLMCBI_02299 4e-179 nptA P phosphate symporter
COCLMCBI_02300 2.6e-218 nptA P phosphate symporter
COCLMCBI_02301 4.7e-37
COCLMCBI_02302 1.8e-160 P PBP superfamily domain
COCLMCBI_02304 2.1e-09
COCLMCBI_02305 7.7e-96 S Domain of unknown function (DUF1707)
COCLMCBI_02306 1.2e-241 alaA 2.6.1.2, 2.6.1.66 E Aspartate tyrosine aromatic aminotransferase
COCLMCBI_02307 0.0 crpB M Large extracellular alpha-helical protein
COCLMCBI_02308 2.8e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COCLMCBI_02310 1.4e-98 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
COCLMCBI_02312 8e-55 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COCLMCBI_02313 6.5e-128 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COCLMCBI_02314 6.5e-285 vanW V vancomycin resistance protein
COCLMCBI_02315 3.5e-179 lpqI 3.2.1.52 G Beta-glucosidase-related glycosidases
COCLMCBI_02316 9.7e-27 S Protein of unknown function (DUF2613)
COCLMCBI_02317 0.0 aftD I Domain of unknown function (DUF3367)
COCLMCBI_02318 1.7e-173 I Acyltransferase
COCLMCBI_02319 6.1e-86 S Protein of unknown function (DUF3068)
COCLMCBI_02320 6.5e-242
COCLMCBI_02321 2.6e-181 M Glycosyltransferase, group 1 family protein
COCLMCBI_02322 1.4e-136 bioC 2.1.1.197 Q (SAM)-dependent
COCLMCBI_02323 0.0 pckG 4.1.1.32, 4.1.1.49 H Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
COCLMCBI_02324 2.9e-134 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COCLMCBI_02325 2e-126 S NYN domain
COCLMCBI_02326 0.0 mmpL3 S drug exporters of the RND superfamily
COCLMCBI_02327 1.6e-164 S integral membrane protein
COCLMCBI_02328 2.5e-101 M LPXTG-motif cell wall anchor domain protein
COCLMCBI_02329 2.3e-11 M LPXTG-motif cell wall anchor domain protein
COCLMCBI_02330 4.5e-17 S integral membrane protein
COCLMCBI_02331 2.5e-271 1.3.1.72 C FAD FMN-containing dehydrogenases
COCLMCBI_02332 5.7e-263 cma 2.1.1.79 M Cyclopropane fatty acid synthase and related methyltransferases
COCLMCBI_02333 1.2e-59 S Protein of unknown function (DUF3054)
COCLMCBI_02335 3.7e-72 M LPXTG-motif cell wall anchor domain protein
COCLMCBI_02336 1.5e-33 S Type I phosphodiesterase / nucleotide pyrophosphatase
COCLMCBI_02337 2.4e-108 S Type I phosphodiesterase / nucleotide pyrophosphatase
COCLMCBI_02338 1.9e-107 3.6.3.30 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
COCLMCBI_02339 1.1e-102 P Binding-protein-dependent transport system inner membrane component
COCLMCBI_02340 6e-20 P Binding-protein-dependent transport systems inner membrane component
COCLMCBI_02341 3e-31 P Binding-protein-dependent transport systems inner membrane component
COCLMCBI_02342 1.4e-32 P Bacterial extracellular solute-binding protein
COCLMCBI_02343 6.7e-52 P Bacterial extracellular solute-binding protein
COCLMCBI_02344 4.2e-97 pgmB 3.1.3.18, 5.4.2.6 S HAD hydrolase, family IA, variant 3
COCLMCBI_02345 1.9e-107 2.7.7.7 L DNA polymerase III, epsilon subunit
COCLMCBI_02346 3.9e-245 yfjM K Protein of unknown function DUF262
COCLMCBI_02347 1.9e-88 3.6.4.13 L Restriction endonuclease
COCLMCBI_02348 2.7e-28 3.6.4.13 L Restriction endonuclease
COCLMCBI_02349 2.9e-25 3.6.4.13 L Restriction endonuclease
COCLMCBI_02350 0.0 3.6.4.13 L Restriction endonuclease
COCLMCBI_02352 2.3e-08 D Domain of Unknown Function (DUF349)
COCLMCBI_02353 1.1e-12 tnp3521a1 L Transposase and inactivated derivatives
COCLMCBI_02354 6.9e-109 L Transposase and inactivated derivatives
COCLMCBI_02355 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_02356 9e-50 L Transposase and inactivated derivatives
COCLMCBI_02357 3.2e-115 L Transposase and inactivated derivatives
COCLMCBI_02360 3.1e-205
COCLMCBI_02361 4e-43 arsR K transcriptional
COCLMCBI_02362 3.8e-47 sbcC L DNA repair
COCLMCBI_02363 4.8e-43 sbcC L DNA repair
COCLMCBI_02364 1e-19 sbcC L DNA repair
COCLMCBI_02365 2.2e-31 sbcD L DNA repair exonuclease
COCLMCBI_02366 1.9e-20 sbcD L DNA repair exonuclease
COCLMCBI_02367 1.7e-31 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02368 1.6e-77 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02369 6.5e-49 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02370 4.3e-91 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02371 4.1e-61 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02372 5.9e-35 helZ 2.7.11.1 L SNF2 family
COCLMCBI_02373 3.4e-278 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COCLMCBI_02374 1.4e-121 L HNH endonuclease
COCLMCBI_02375 2.1e-77
COCLMCBI_02376 2.9e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation
COCLMCBI_02377 2.9e-84 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COCLMCBI_02378 8.4e-106 rhtC E threonine efflux protein
COCLMCBI_02380 3.3e-55
COCLMCBI_02382 3.2e-08
COCLMCBI_02383 1.9e-53 nudG 3.6.1.55, 3.6.1.65 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_02384 1.8e-174 dcm 2.1.1.37 L DNA restriction-modification system
COCLMCBI_02385 4.2e-17 V endonuclease activity
COCLMCBI_02386 2.4e-10 V endonuclease activity
COCLMCBI_02388 2.2e-111 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COCLMCBI_02389 5.7e-67 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COCLMCBI_02390 2.1e-153 blt EGP Major facilitator Superfamily
COCLMCBI_02391 7.8e-29
COCLMCBI_02393 3.8e-69
COCLMCBI_02394 9.7e-171 lipT CE10 I Belongs to the type-B carboxylesterase lipase family
COCLMCBI_02395 1.1e-126
COCLMCBI_02396 5.4e-78
COCLMCBI_02397 3.6e-30 blt EGP Major facilitator Superfamily
COCLMCBI_02398 6e-41 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COCLMCBI_02399 6.4e-125 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
COCLMCBI_02401 5.1e-56 V HNH endonuclease
COCLMCBI_02402 1.8e-174 dcm 2.1.1.37 L DNA restriction-modification system
COCLMCBI_02403 1.7e-53 nudG 3.6.1.55, 3.6.1.65 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
COCLMCBI_02404 9.4e-153 tnp7109-46 L Transposase and inactivated derivatives
COCLMCBI_02405 9e-50 L Transposase and inactivated derivatives
COCLMCBI_02406 3.1e-59 L Transposase and inactivated derivatives
COCLMCBI_02409 2.5e-247
COCLMCBI_02410 4e-43 arsR K transcriptional
COCLMCBI_02411 2.5e-190 arsB P Arsenite efflux pump ACR3 and related permeases
COCLMCBI_02412 4.3e-71 arsC 1.20.4.1, 2.8.4.2 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COCLMCBI_02413 8.6e-76 S Protein of unknown function, DUF488
COCLMCBI_02414 1.2e-43 birA 2.7.1.33, 6.3.4.15 H Biotin-(Acetyl-CoA carboxylase) ligase
COCLMCBI_02415 4.2e-56 birA 2.7.1.33, 6.3.4.15 H Biotin-(Acetyl-CoA carboxylase) ligase
COCLMCBI_02416 3.9e-67 S Bacterial PH domain
COCLMCBI_02417 2e-138 budA 4.1.1.5 Q Belongs to the alpha-acetolactate decarboxylase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)