ORF_ID e_value Gene_name EC_number CAZy COGs Description
MCOOGMHK_00001 1.1e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MCOOGMHK_00002 1.5e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MCOOGMHK_00003 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCOOGMHK_00004 2.9e-207 K helix_turn _helix lactose operon repressor
MCOOGMHK_00005 7.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCOOGMHK_00006 6.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MCOOGMHK_00007 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCOOGMHK_00008 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MCOOGMHK_00009 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MCOOGMHK_00010 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
MCOOGMHK_00011 3.4e-212 gatC G PTS system sugar-specific permease component
MCOOGMHK_00012 1.4e-173 K Putative sugar-binding domain
MCOOGMHK_00014 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MCOOGMHK_00015 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
MCOOGMHK_00016 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MCOOGMHK_00017 9.7e-34 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MCOOGMHK_00018 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MCOOGMHK_00019 8.2e-28 mgtC S MgtC family
MCOOGMHK_00020 1.6e-83 mgtC S MgtC family
MCOOGMHK_00022 6.9e-201
MCOOGMHK_00024 1.5e-190
MCOOGMHK_00025 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MCOOGMHK_00028 2.4e-176 S Auxin Efflux Carrier
MCOOGMHK_00029 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCOOGMHK_00030 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MCOOGMHK_00031 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCOOGMHK_00033 7.6e-92 ilvN 2.2.1.6 E ACT domain
MCOOGMHK_00034 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MCOOGMHK_00035 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCOOGMHK_00036 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MCOOGMHK_00037 5.1e-113 yceD S Uncharacterized ACR, COG1399
MCOOGMHK_00038 3.6e-107
MCOOGMHK_00039 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCOOGMHK_00040 2e-58 S Protein of unknown function (DUF3039)
MCOOGMHK_00041 0.0 yjjK S ABC transporter
MCOOGMHK_00042 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
MCOOGMHK_00043 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCOOGMHK_00044 1.4e-164 P Cation efflux family
MCOOGMHK_00045 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCOOGMHK_00046 1.5e-219 S Endonuclease/Exonuclease/phosphatase family
MCOOGMHK_00047 5.9e-94 argO S LysE type translocator
MCOOGMHK_00048 2.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
MCOOGMHK_00049 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MCOOGMHK_00050 8.8e-34 CP_0960 S Belongs to the UPF0109 family
MCOOGMHK_00051 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCOOGMHK_00052 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MCOOGMHK_00053 8.9e-83 hsp20 O Hsp20/alpha crystallin family
MCOOGMHK_00054 3.1e-107 XK27_02070 S Nitroreductase family
MCOOGMHK_00055 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MCOOGMHK_00056 1.1e-244 U Sodium:dicarboxylate symporter family
MCOOGMHK_00057 0.0
MCOOGMHK_00060 4.5e-220 steT E amino acid
MCOOGMHK_00061 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MCOOGMHK_00062 1.4e-29 rpmB J Ribosomal L28 family
MCOOGMHK_00063 6.5e-201 yegV G pfkB family carbohydrate kinase
MCOOGMHK_00065 5e-243 yxiO S Vacuole effluxer Atg22 like
MCOOGMHK_00066 2e-132 K helix_turn_helix, mercury resistance
MCOOGMHK_00067 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
MCOOGMHK_00068 3.7e-54 relB L RelB antitoxin
MCOOGMHK_00069 1.1e-236 K Helix-turn-helix XRE-family like proteins
MCOOGMHK_00070 3.5e-129 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MCOOGMHK_00075 2e-28
MCOOGMHK_00076 3.5e-07 S Scramblase
MCOOGMHK_00077 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCOOGMHK_00078 2.1e-42 K Transcriptional regulator
MCOOGMHK_00081 2.6e-68 M Belongs to the glycosyl hydrolase 28 family
MCOOGMHK_00082 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MCOOGMHK_00083 4.2e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
MCOOGMHK_00084 5e-119 K Bacterial regulatory proteins, tetR family
MCOOGMHK_00085 1.6e-132 M Mechanosensitive ion channel
MCOOGMHK_00086 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MCOOGMHK_00087 1.7e-27 2.1.1.72 S Protein conserved in bacteria
MCOOGMHK_00088 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MCOOGMHK_00089 7.5e-95 S Domain of unknown function (DUF4854)
MCOOGMHK_00090 7.4e-214 3.4.22.70 M Sortase family
MCOOGMHK_00091 8.7e-282 M LPXTG cell wall anchor motif
MCOOGMHK_00092 0.0 inlJ M domain protein
MCOOGMHK_00093 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
MCOOGMHK_00094 5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MCOOGMHK_00095 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCOOGMHK_00096 3.9e-129 M Protein of unknown function (DUF3152)
MCOOGMHK_00097 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MCOOGMHK_00099 1e-69 E Domain of unknown function (DUF5011)
MCOOGMHK_00100 6.5e-46 S Parallel beta-helix repeats
MCOOGMHK_00101 1.9e-14 S Parallel beta-helix repeats
MCOOGMHK_00103 6.6e-70 rplI J Binds to the 23S rRNA
MCOOGMHK_00104 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCOOGMHK_00105 1.1e-79 ssb1 L Single-stranded DNA-binding protein
MCOOGMHK_00106 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MCOOGMHK_00107 4.5e-172 T Pfam Adenylate and Guanylate cyclase catalytic domain
MCOOGMHK_00108 4.3e-116
MCOOGMHK_00109 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MCOOGMHK_00110 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCOOGMHK_00111 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
MCOOGMHK_00112 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MCOOGMHK_00113 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MCOOGMHK_00114 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MCOOGMHK_00115 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
MCOOGMHK_00116 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
MCOOGMHK_00117 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCOOGMHK_00119 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MCOOGMHK_00120 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCOOGMHK_00121 1.4e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCOOGMHK_00122 4.8e-215 K Psort location Cytoplasmic, score
MCOOGMHK_00123 3.1e-40 rpmA J Ribosomal L27 protein
MCOOGMHK_00124 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MCOOGMHK_00125 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MCOOGMHK_00126 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
MCOOGMHK_00127 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MCOOGMHK_00128 3.3e-256 V Efflux ABC transporter, permease protein
MCOOGMHK_00129 8.3e-165 V ATPases associated with a variety of cellular activities
MCOOGMHK_00130 6.8e-57
MCOOGMHK_00131 9.9e-67
MCOOGMHK_00132 1.1e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MCOOGMHK_00133 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MCOOGMHK_00134 1.8e-240 hom 1.1.1.3 E Homoserine dehydrogenase
MCOOGMHK_00135 1.9e-289 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MCOOGMHK_00136 2.7e-40 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MCOOGMHK_00137 3e-187 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCOOGMHK_00138 1e-108 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCOOGMHK_00139 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MCOOGMHK_00140 4.7e-182 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MCOOGMHK_00141 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MCOOGMHK_00142 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MCOOGMHK_00144 6.8e-164 IQ KR domain
MCOOGMHK_00145 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
MCOOGMHK_00146 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
MCOOGMHK_00147 6.3e-185 K Bacterial regulatory proteins, lacI family
MCOOGMHK_00150 1.4e-118 cyaA 4.6.1.1 S CYTH
MCOOGMHK_00151 8.5e-163 trxA2 O Tetratricopeptide repeat
MCOOGMHK_00152 7.9e-180
MCOOGMHK_00153 5.8e-189
MCOOGMHK_00154 1.2e-164 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MCOOGMHK_00155 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCOOGMHK_00156 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCOOGMHK_00157 4.9e-128
MCOOGMHK_00158 2.1e-131 K Bacterial regulatory proteins, tetR family
MCOOGMHK_00159 1.7e-50 G Transmembrane secretion effector
MCOOGMHK_00160 2.6e-158 G Transmembrane secretion effector
MCOOGMHK_00161 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCOOGMHK_00162 2.3e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
MCOOGMHK_00163 7.1e-182 S CAAX protease self-immunity
MCOOGMHK_00165 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MCOOGMHK_00166 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCOOGMHK_00167 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCOOGMHK_00168 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MCOOGMHK_00169 2.2e-251 S Calcineurin-like phosphoesterase
MCOOGMHK_00172 3.5e-67 S Domain of unknown function (DUF4143)
MCOOGMHK_00173 5.6e-103 S Domain of unknown function (DUF4143)
MCOOGMHK_00174 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCOOGMHK_00176 1.1e-124 S HAD hydrolase, family IA, variant 3
MCOOGMHK_00177 8.6e-201 P NMT1/THI5 like
MCOOGMHK_00178 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MCOOGMHK_00179 5.8e-145
MCOOGMHK_00180 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MCOOGMHK_00181 4e-262 EGP Major facilitator Superfamily
MCOOGMHK_00182 6.8e-98 S GtrA-like protein
MCOOGMHK_00183 1.3e-62 S Macrophage migration inhibitory factor (MIF)
MCOOGMHK_00184 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MCOOGMHK_00185 0.0 pepD E Peptidase family C69
MCOOGMHK_00186 1.3e-107 S Phosphatidylethanolamine-binding protein
MCOOGMHK_00187 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MCOOGMHK_00188 0.0 lmrA2 V ABC transporter transmembrane region
MCOOGMHK_00189 0.0 lmrA1 V ABC transporter, ATP-binding protein
MCOOGMHK_00190 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MCOOGMHK_00191 3.3e-191 1.1.1.65 C Aldo/keto reductase family
MCOOGMHK_00193 4e-100 M Belongs to the glycosyl hydrolase 30 family
MCOOGMHK_00194 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
MCOOGMHK_00196 1.3e-258 L Phage integrase, N-terminal SAM-like domain
MCOOGMHK_00199 4.7e-105
MCOOGMHK_00200 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
MCOOGMHK_00201 1.4e-59 S Bacterial mobilisation protein (MobC)
MCOOGMHK_00202 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MCOOGMHK_00203 2e-180 V Abi-like protein
MCOOGMHK_00204 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
MCOOGMHK_00206 7.6e-299 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MCOOGMHK_00207 5.6e-272
MCOOGMHK_00208 1.4e-13
MCOOGMHK_00209 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
MCOOGMHK_00210 5e-116 K WHG domain
MCOOGMHK_00211 3.6e-37 L Psort location Cytoplasmic, score 8.87
MCOOGMHK_00212 2.1e-134 L Integrase core domain
MCOOGMHK_00213 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
MCOOGMHK_00214 1.5e-265 EGP Major Facilitator Superfamily
MCOOGMHK_00215 1.2e-132
MCOOGMHK_00216 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCOOGMHK_00217 5.5e-55 L HNH endonuclease
MCOOGMHK_00218 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCOOGMHK_00219 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MCOOGMHK_00220 1.6e-105 L Transposase
MCOOGMHK_00221 4.2e-42 XAC3035 O Glutaredoxin
MCOOGMHK_00222 7.4e-151 S Virulence factor BrkB
MCOOGMHK_00223 7.6e-100 bcp 1.11.1.15 O Redoxin
MCOOGMHK_00224 1.2e-39 E ABC transporter
MCOOGMHK_00225 6.7e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCOOGMHK_00226 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCOOGMHK_00227 0.0 V FtsX-like permease family
MCOOGMHK_00228 2.6e-129 V ABC transporter
MCOOGMHK_00229 2.4e-101 K Transcriptional regulator C-terminal region
MCOOGMHK_00230 1.8e-276 aroP E aromatic amino acid transport protein AroP K03293
MCOOGMHK_00231 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCOOGMHK_00233 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MCOOGMHK_00234 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCOOGMHK_00235 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCOOGMHK_00236 5e-254 yhjE EGP Sugar (and other) transporter
MCOOGMHK_00237 7e-298 scrT G Transporter major facilitator family protein
MCOOGMHK_00238 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MCOOGMHK_00239 8.4e-193 K helix_turn _helix lactose operon repressor
MCOOGMHK_00240 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCOOGMHK_00241 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCOOGMHK_00242 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCOOGMHK_00243 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MCOOGMHK_00244 2.5e-247 3.5.1.104 G Polysaccharide deacetylase
MCOOGMHK_00245 4.9e-57 K Cro/C1-type HTH DNA-binding domain
MCOOGMHK_00246 2e-12 E IrrE N-terminal-like domain
MCOOGMHK_00247 3.9e-50 E IrrE N-terminal-like domain
MCOOGMHK_00248 6.8e-65
MCOOGMHK_00249 1.9e-61
MCOOGMHK_00251 2.3e-127 S Domain of unknown function (DUF4417)
MCOOGMHK_00252 1.9e-42 S Bacterial mobilisation protein (MobC)
MCOOGMHK_00253 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCOOGMHK_00255 3.9e-173 htpX O Belongs to the peptidase M48B family
MCOOGMHK_00256 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MCOOGMHK_00257 0.0 cadA P E1-E2 ATPase
MCOOGMHK_00258 3.9e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MCOOGMHK_00259 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MCOOGMHK_00261 3.9e-15 2.7.7.7 L Transposase, Mutator family
MCOOGMHK_00262 2.6e-57 M Glycosyl hydrolases family 25
MCOOGMHK_00263 1.1e-36 CP_0155 3.5.1.28 M LysM domain
MCOOGMHK_00264 5.2e-33
MCOOGMHK_00265 7e-116 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MCOOGMHK_00266 3.2e-79 L HindVP restriction endonuclease
MCOOGMHK_00268 8.6e-13
MCOOGMHK_00269 6.4e-16 L Phage integrase family
MCOOGMHK_00270 5.6e-42 tnp7109-21 L Integrase core domain
MCOOGMHK_00271 1.5e-53 tnp7109-21 L Integrase core domain
MCOOGMHK_00272 3.4e-32 L transposase activity
MCOOGMHK_00273 7e-86 yjcF Q Acetyltransferase (GNAT) domain
MCOOGMHK_00274 3.8e-156 I Serine aminopeptidase, S33
MCOOGMHK_00275 9.3e-53 ybjQ S Putative heavy-metal-binding
MCOOGMHK_00276 3.3e-41 D DivIVA domain protein
MCOOGMHK_00277 1.3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MCOOGMHK_00278 0.0 KL Domain of unknown function (DUF3427)
MCOOGMHK_00280 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCOOGMHK_00282 2e-103
MCOOGMHK_00283 6.2e-166 yicL EG EamA-like transporter family
MCOOGMHK_00284 1.9e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
MCOOGMHK_00285 1.8e-162 pip S YhgE Pip domain protein
MCOOGMHK_00286 1e-166 pip S YhgE Pip domain protein
MCOOGMHK_00287 0.0 pip S YhgE Pip domain protein
MCOOGMHK_00288 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MCOOGMHK_00289 1e-130 fhaA T Protein of unknown function (DUF2662)
MCOOGMHK_00290 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MCOOGMHK_00291 4.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MCOOGMHK_00292 2.8e-266 rodA D Belongs to the SEDS family
MCOOGMHK_00293 3.7e-263 pbpA M penicillin-binding protein
MCOOGMHK_00294 2e-183 T Protein tyrosine kinase
MCOOGMHK_00295 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MCOOGMHK_00296 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MCOOGMHK_00297 1.8e-231 srtA 3.4.22.70 M Sortase family
MCOOGMHK_00298 7.9e-143 S Bacterial protein of unknown function (DUF881)
MCOOGMHK_00299 2.6e-71 crgA D Involved in cell division
MCOOGMHK_00300 1.4e-256 L ribosomal rna small subunit methyltransferase
MCOOGMHK_00301 1.3e-120 L HTH-like domain
MCOOGMHK_00302 1.9e-144 gluP 3.4.21.105 S Rhomboid family
MCOOGMHK_00303 3.4e-35
MCOOGMHK_00304 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MCOOGMHK_00305 2e-73 I Sterol carrier protein
MCOOGMHK_00306 8.7e-46 L Transposase
MCOOGMHK_00307 2.5e-52 L IstB-like ATP binding protein
MCOOGMHK_00308 1.1e-42 tnp7109-21 L Integrase core domain
MCOOGMHK_00309 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MCOOGMHK_00310 3.5e-12
MCOOGMHK_00311 2e-118 K Bacterial regulatory proteins, tetR family
MCOOGMHK_00312 1.5e-215 G Transmembrane secretion effector
MCOOGMHK_00313 4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCOOGMHK_00314 1.5e-101
MCOOGMHK_00315 2.6e-43 3.6.1.13 L NUDIX domain
MCOOGMHK_00316 2.6e-227 glf 5.4.99.9 M UDP-galactopyranose mutase
MCOOGMHK_00317 3.8e-194 L Transposase, Mutator family
MCOOGMHK_00318 2.7e-156 bglA 3.2.1.21 G Glycosyl hydrolase family 1
MCOOGMHK_00319 9.5e-45 L Transposase DDE domain
MCOOGMHK_00321 3.3e-09
MCOOGMHK_00322 2.6e-43 L Transposase
MCOOGMHK_00323 7.3e-119 tnp7109-21 L Integrase core domain
MCOOGMHK_00324 1.2e-153 K Transposase IS116 IS110 IS902
MCOOGMHK_00325 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MCOOGMHK_00326 3.2e-215 1.1.1.22 M UDP binding domain
MCOOGMHK_00327 0.0 wbbM M Glycosyl transferase family 8
MCOOGMHK_00328 2.5e-139 rgpC U Transport permease protein
MCOOGMHK_00329 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MCOOGMHK_00330 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
MCOOGMHK_00331 5.6e-121 L Protein of unknown function (DUF1524)
MCOOGMHK_00332 2.1e-142 M Putative cell wall binding repeat 2
MCOOGMHK_00333 5.7e-254 L Transposase
MCOOGMHK_00334 9.8e-127 L IstB-like ATP binding protein
MCOOGMHK_00335 0.0 M Belongs to the glycosyl hydrolase 43 family
MCOOGMHK_00336 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
MCOOGMHK_00337 0.0 wbbM M Glycosyl transferase family 8
MCOOGMHK_00338 4.3e-298
MCOOGMHK_00339 1.3e-207 S Acyltransferase family
MCOOGMHK_00340 2.8e-72 L Transposase
MCOOGMHK_00341 6.5e-167 rfbJ M Glycosyl transferase family 2
MCOOGMHK_00342 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MCOOGMHK_00343 1.1e-24 I transferase activity, transferring acyl groups other than amino-acyl groups
MCOOGMHK_00344 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCOOGMHK_00345 2.7e-111 T protein histidine kinase activity
MCOOGMHK_00346 1e-47 S Protein of unknown function (DUF3073)
MCOOGMHK_00347 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCOOGMHK_00348 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_00349 1.4e-177 S Amidohydrolase family
MCOOGMHK_00350 0.0 yjjP S Threonine/Serine exporter, ThrE
MCOOGMHK_00351 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MCOOGMHK_00352 4.3e-239 yhjX EGP Major facilitator Superfamily
MCOOGMHK_00353 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCOOGMHK_00354 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MCOOGMHK_00355 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MCOOGMHK_00356 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MCOOGMHK_00357 1.1e-95 K helix_turn _helix lactose operon repressor
MCOOGMHK_00358 3.6e-241 ytfL P Transporter associated domain
MCOOGMHK_00359 1.3e-188 yddG EG EamA-like transporter family
MCOOGMHK_00360 1.9e-83 dps P Belongs to the Dps family
MCOOGMHK_00361 1.9e-135 S Protein of unknown function DUF45
MCOOGMHK_00362 2.8e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MCOOGMHK_00363 9.6e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MCOOGMHK_00364 4.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MCOOGMHK_00365 3.9e-190 K helix_turn _helix lactose operon repressor
MCOOGMHK_00366 0.0 G Glycosyl hydrolase family 20, domain 2
MCOOGMHK_00369 0.0 3.2.1.55 GH51 G arabinose metabolic process
MCOOGMHK_00370 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCOOGMHK_00371 2.5e-124 gntR K FCD
MCOOGMHK_00372 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MCOOGMHK_00373 2.1e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MCOOGMHK_00375 8.3e-09 K helix_turn _helix lactose operon repressor
MCOOGMHK_00376 2.6e-227 I Serine aminopeptidase, S33
MCOOGMHK_00377 1.6e-187 K Periplasmic binding protein domain
MCOOGMHK_00378 4.6e-187 G Glycosyl hydrolases family 43
MCOOGMHK_00380 2.6e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
MCOOGMHK_00381 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
MCOOGMHK_00382 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCOOGMHK_00383 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCOOGMHK_00384 2e-87 S Protein of unknown function (DUF721)
MCOOGMHK_00385 2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCOOGMHK_00386 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCOOGMHK_00387 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCOOGMHK_00388 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MCOOGMHK_00389 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
MCOOGMHK_00390 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
MCOOGMHK_00391 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MCOOGMHK_00392 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MCOOGMHK_00393 1.2e-242 parB K Belongs to the ParB family
MCOOGMHK_00394 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCOOGMHK_00395 0.0 murJ KLT MviN-like protein
MCOOGMHK_00396 0.0 M Conserved repeat domain
MCOOGMHK_00397 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MCOOGMHK_00398 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MCOOGMHK_00399 6.7e-113 S LytR cell envelope-related transcriptional attenuator
MCOOGMHK_00400 2.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MCOOGMHK_00401 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCOOGMHK_00402 1.2e-211 S G5
MCOOGMHK_00404 7.1e-150 O Thioredoxin
MCOOGMHK_00405 0.0 KLT Protein tyrosine kinase
MCOOGMHK_00406 1.3e-173 K Psort location Cytoplasmic, score
MCOOGMHK_00407 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
MCOOGMHK_00408 2.3e-101 L Helix-turn-helix domain
MCOOGMHK_00409 0.0 S LPXTG-motif cell wall anchor domain protein
MCOOGMHK_00410 0.0 S LPXTG-motif cell wall anchor domain protein
MCOOGMHK_00411 1.4e-250 M LPXTG-motif cell wall anchor domain protein
MCOOGMHK_00412 4.5e-180 3.4.22.70 M Sortase family
MCOOGMHK_00413 5.4e-153
MCOOGMHK_00414 1e-270 KLT Domain of unknown function (DUF4032)
MCOOGMHK_00415 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCOOGMHK_00417 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MCOOGMHK_00418 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MCOOGMHK_00419 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MCOOGMHK_00420 0.0 yjcE P Sodium/hydrogen exchanger family
MCOOGMHK_00421 1.2e-145 ypfH S Phospholipase/Carboxylesterase
MCOOGMHK_00422 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCOOGMHK_00423 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MCOOGMHK_00424 4e-144 cobB2 K Sir2 family
MCOOGMHK_00425 1.1e-45
MCOOGMHK_00426 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MCOOGMHK_00427 3e-69 S Protein of unknown function (DUF4235)
MCOOGMHK_00428 1.8e-138 G Phosphoglycerate mutase family
MCOOGMHK_00431 2.9e-190 K Psort location Cytoplasmic, score
MCOOGMHK_00432 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MCOOGMHK_00433 0.0 dnaK O Heat shock 70 kDa protein
MCOOGMHK_00434 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCOOGMHK_00436 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
MCOOGMHK_00437 2.6e-86 hspR K transcriptional regulator, MerR family
MCOOGMHK_00438 1.1e-186 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MCOOGMHK_00439 1.8e-230 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MCOOGMHK_00440 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
MCOOGMHK_00441 3.5e-134 S HAD hydrolase, family IA, variant 3
MCOOGMHK_00443 2.7e-126 dedA S SNARE associated Golgi protein
MCOOGMHK_00444 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCOOGMHK_00445 8.6e-59
MCOOGMHK_00446 3.6e-130
MCOOGMHK_00447 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCOOGMHK_00448 8.9e-87 K Transcriptional regulator
MCOOGMHK_00450 4.2e-275 xylR 5.3.1.12 G MFS/sugar transport protein
MCOOGMHK_00451 1.3e-184 tatD L TatD related DNase
MCOOGMHK_00452 0.0 kup P Transport of potassium into the cell
MCOOGMHK_00453 3.3e-166 S Glutamine amidotransferase domain
MCOOGMHK_00454 2.1e-137 T HD domain
MCOOGMHK_00455 1.1e-181 V ABC transporter
MCOOGMHK_00456 1.1e-246 V ABC transporter permease
MCOOGMHK_00457 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MCOOGMHK_00458 0.0 S Psort location Cytoplasmic, score 8.87
MCOOGMHK_00459 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MCOOGMHK_00460 8.7e-27 thiS 2.8.1.10 H ThiS family
MCOOGMHK_00462 5.2e-262
MCOOGMHK_00463 2.5e-208 S Glycosyltransferase, group 2 family protein
MCOOGMHK_00464 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MCOOGMHK_00465 2.1e-42 cbiM P PDGLE domain
MCOOGMHK_00466 3.3e-90
MCOOGMHK_00467 5.1e-220 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MCOOGMHK_00468 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MCOOGMHK_00470 7.5e-152 cpaE D bacterial-type flagellum organization
MCOOGMHK_00471 3.4e-191 cpaF U Type II IV secretion system protein
MCOOGMHK_00472 7.4e-121 U Type ii secretion system
MCOOGMHK_00473 1.4e-14 gspF NU Type II secretion system (T2SS), protein F
MCOOGMHK_00474 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
MCOOGMHK_00475 1.9e-41 S Protein of unknown function (DUF4244)
MCOOGMHK_00476 2e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
MCOOGMHK_00477 3.2e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MCOOGMHK_00478 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MCOOGMHK_00479 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCOOGMHK_00480 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MCOOGMHK_00481 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
MCOOGMHK_00483 1.1e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCOOGMHK_00484 1.7e-116
MCOOGMHK_00485 1.2e-288 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCOOGMHK_00486 4.3e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCOOGMHK_00487 3.9e-278 S Calcineurin-like phosphoesterase
MCOOGMHK_00488 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MCOOGMHK_00489 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MCOOGMHK_00490 4.6e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
MCOOGMHK_00491 3e-122 yplQ S Haemolysin-III related
MCOOGMHK_00492 0.0 vpr M PA domain
MCOOGMHK_00493 6.4e-183 3.6.1.27 I PAP2 superfamily
MCOOGMHK_00494 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCOOGMHK_00495 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCOOGMHK_00496 6.3e-213 holB 2.7.7.7 L DNA polymerase III
MCOOGMHK_00497 4.4e-200 K helix_turn _helix lactose operon repressor
MCOOGMHK_00498 5e-38 ptsH G PTS HPr component phosphorylation site
MCOOGMHK_00499 1.2e-289 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCOOGMHK_00500 2e-56 S Fic/DOC family
MCOOGMHK_00501 1.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MCOOGMHK_00502 2e-18 G MFS/sugar transport protein
MCOOGMHK_00503 3.9e-307 efeU_1 P Iron permease FTR1 family
MCOOGMHK_00504 5.4e-108 tpd P Fe2+ transport protein
MCOOGMHK_00505 1.6e-233 S Predicted membrane protein (DUF2318)
MCOOGMHK_00506 9.7e-223 macB_2 V ABC transporter permease
MCOOGMHK_00507 5.9e-204 Z012_06715 V FtsX-like permease family
MCOOGMHK_00508 1.8e-147 macB V ABC transporter, ATP-binding protein
MCOOGMHK_00509 1.3e-70 S FMN_bind
MCOOGMHK_00510 3.6e-131 yydK K UTRA
MCOOGMHK_00511 4.6e-67 S haloacid dehalogenase-like hydrolase
MCOOGMHK_00512 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCOOGMHK_00513 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MCOOGMHK_00514 3.3e-42 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MCOOGMHK_00515 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
MCOOGMHK_00516 5.8e-33 Q phosphatase activity
MCOOGMHK_00517 7e-81
MCOOGMHK_00518 3.5e-241 S Putative ABC-transporter type IV
MCOOGMHK_00519 4.7e-162 S Sucrose-6F-phosphate phosphohydrolase
MCOOGMHK_00521 2e-180 3.4.22.70 M Sortase family
MCOOGMHK_00522 0.0 M chlorophyll binding
MCOOGMHK_00523 5.8e-305 M LPXTG cell wall anchor motif
MCOOGMHK_00524 2.7e-82 K Winged helix DNA-binding domain
MCOOGMHK_00525 1.8e-301 V ABC transporter, ATP-binding protein
MCOOGMHK_00526 0.0 V ABC transporter transmembrane region
MCOOGMHK_00527 2e-82
MCOOGMHK_00528 1.1e-68 XK26_04485 P Cobalt transport protein
MCOOGMHK_00529 2.9e-19 XK26_04485 P Cobalt transport protein
MCOOGMHK_00531 8.4e-306 pepD E Peptidase family C69
MCOOGMHK_00532 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MCOOGMHK_00533 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
MCOOGMHK_00534 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
MCOOGMHK_00536 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCOOGMHK_00537 3.8e-219 amt U Ammonium Transporter Family
MCOOGMHK_00538 1e-54 glnB K Nitrogen regulatory protein P-II
MCOOGMHK_00539 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MCOOGMHK_00540 3.5e-20 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MCOOGMHK_00541 3.5e-250 dinF V MatE
MCOOGMHK_00542 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MCOOGMHK_00543 2.5e-281 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MCOOGMHK_00544 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MCOOGMHK_00545 3.5e-19 S granule-associated protein
MCOOGMHK_00546 0.0 ubiB S ABC1 family
MCOOGMHK_00547 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MCOOGMHK_00548 9.6e-43 csoR S Metal-sensitive transcriptional repressor
MCOOGMHK_00549 2.9e-214 rmuC S RmuC family
MCOOGMHK_00550 1.6e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCOOGMHK_00551 5.9e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MCOOGMHK_00552 1e-60 V ABC transporter
MCOOGMHK_00553 3.7e-82 V ABC transporter
MCOOGMHK_00554 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCOOGMHK_00555 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCOOGMHK_00556 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCOOGMHK_00557 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
MCOOGMHK_00558 2.5e-52 S Protein of unknown function (DUF2469)
MCOOGMHK_00559 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MCOOGMHK_00560 0.0 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MCOOGMHK_00561 7.2e-236 E Aminotransferase class I and II
MCOOGMHK_00562 9.1e-90 lrp_3 K helix_turn_helix ASNC type
MCOOGMHK_00563 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
MCOOGMHK_00564 0.0 S domain protein
MCOOGMHK_00565 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCOOGMHK_00566 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
MCOOGMHK_00567 1.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCOOGMHK_00568 1.8e-133 KT Transcriptional regulatory protein, C terminal
MCOOGMHK_00569 1.4e-125
MCOOGMHK_00570 1.3e-102 mntP P Probably functions as a manganese efflux pump
MCOOGMHK_00573 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MCOOGMHK_00574 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MCOOGMHK_00575 0.0 K RNA polymerase II activating transcription factor binding
MCOOGMHK_00576 1e-44
MCOOGMHK_00578 1.2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MCOOGMHK_00579 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MCOOGMHK_00581 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCOOGMHK_00582 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCOOGMHK_00583 4.1e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCOOGMHK_00584 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCOOGMHK_00585 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCOOGMHK_00586 9.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCOOGMHK_00587 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MCOOGMHK_00588 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MCOOGMHK_00589 5.9e-146 QT PucR C-terminal helix-turn-helix domain
MCOOGMHK_00590 0.0
MCOOGMHK_00591 4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MCOOGMHK_00592 4.2e-93 bioY S BioY family
MCOOGMHK_00593 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MCOOGMHK_00594 7.2e-308 pccB I Carboxyl transferase domain
MCOOGMHK_00595 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MCOOGMHK_00596 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCOOGMHK_00597 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MCOOGMHK_00599 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MCOOGMHK_00600 8.9e-119
MCOOGMHK_00601 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCOOGMHK_00602 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MCOOGMHK_00603 2.6e-151 xylR K purine nucleotide biosynthetic process
MCOOGMHK_00604 1.5e-40 K purine nucleotide biosynthetic process
MCOOGMHK_00605 1.4e-93 lemA S LemA family
MCOOGMHK_00606 0.0 S Predicted membrane protein (DUF2207)
MCOOGMHK_00607 9.2e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCOOGMHK_00608 9.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCOOGMHK_00609 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCOOGMHK_00610 5.6e-98 nrdI F Probably involved in ribonucleotide reductase function
MCOOGMHK_00611 6.3e-41 nrdH O Glutaredoxin
MCOOGMHK_00612 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MCOOGMHK_00613 1.7e-96 L Transposase and inactivated derivatives IS30 family
MCOOGMHK_00614 0.0 yegQ O Peptidase family U32 C-terminal domain
MCOOGMHK_00615 1.6e-185 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MCOOGMHK_00616 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCOOGMHK_00617 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCOOGMHK_00618 7.4e-54 D nuclear chromosome segregation
MCOOGMHK_00619 1.6e-268 pepC 3.4.22.40 E Peptidase C1-like family
MCOOGMHK_00620 2.3e-166 L Excalibur calcium-binding domain
MCOOGMHK_00621 3.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MCOOGMHK_00622 3.4e-242 EGP Major facilitator Superfamily
MCOOGMHK_00623 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
MCOOGMHK_00624 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MCOOGMHK_00625 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCOOGMHK_00626 8.5e-246 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MCOOGMHK_00627 1.4e-127 KT Transcriptional regulatory protein, C terminal
MCOOGMHK_00628 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MCOOGMHK_00629 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
MCOOGMHK_00630 6.2e-180 pstA P Phosphate transport system permease
MCOOGMHK_00631 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCOOGMHK_00632 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_00633 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_00634 8.8e-222 pbuO S Permease family
MCOOGMHK_00636 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
MCOOGMHK_00637 1.7e-182 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
MCOOGMHK_00638 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCOOGMHK_00639 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCOOGMHK_00641 1e-237 T Forkhead associated domain
MCOOGMHK_00642 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MCOOGMHK_00643 9.6e-42
MCOOGMHK_00644 1.6e-109 flgA NO SAF
MCOOGMHK_00645 3.2e-38 fmdB S Putative regulatory protein
MCOOGMHK_00646 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MCOOGMHK_00647 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MCOOGMHK_00648 7.2e-144
MCOOGMHK_00649 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCOOGMHK_00650 3.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
MCOOGMHK_00651 3.4e-56 KLT Associated with various cellular activities
MCOOGMHK_00655 1.9e-25 rpmG J Ribosomal protein L33
MCOOGMHK_00656 9.7e-217 murB 1.3.1.98 M Cell wall formation
MCOOGMHK_00657 9e-61 fdxA C 4Fe-4S binding domain
MCOOGMHK_00658 1.4e-225 dapC E Aminotransferase class I and II
MCOOGMHK_00659 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCOOGMHK_00661 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
MCOOGMHK_00662 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MCOOGMHK_00663 8.9e-112
MCOOGMHK_00664 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MCOOGMHK_00665 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCOOGMHK_00666 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
MCOOGMHK_00667 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MCOOGMHK_00668 6.9e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MCOOGMHK_00669 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MCOOGMHK_00670 6.2e-157 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MCOOGMHK_00671 9.7e-90 ywiC S YwiC-like protein
MCOOGMHK_00672 1.4e-58 ywiC S YwiC-like protein
MCOOGMHK_00673 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MCOOGMHK_00674 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCOOGMHK_00675 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
MCOOGMHK_00676 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCOOGMHK_00677 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCOOGMHK_00678 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCOOGMHK_00679 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCOOGMHK_00680 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCOOGMHK_00681 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCOOGMHK_00682 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MCOOGMHK_00683 2.2e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCOOGMHK_00684 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCOOGMHK_00685 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCOOGMHK_00686 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCOOGMHK_00687 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCOOGMHK_00688 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCOOGMHK_00689 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCOOGMHK_00690 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCOOGMHK_00691 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCOOGMHK_00692 1e-24 rpmD J Ribosomal protein L30p/L7e
MCOOGMHK_00693 2.7e-63 rplO J binds to the 23S rRNA
MCOOGMHK_00694 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCOOGMHK_00695 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCOOGMHK_00696 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCOOGMHK_00697 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MCOOGMHK_00698 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCOOGMHK_00699 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCOOGMHK_00700 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCOOGMHK_00701 8.1e-64 rplQ J Ribosomal protein L17
MCOOGMHK_00702 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
MCOOGMHK_00703 3.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCOOGMHK_00704 0.0 gcs2 S A circularly permuted ATPgrasp
MCOOGMHK_00705 1.3e-153 E Transglutaminase/protease-like homologues
MCOOGMHK_00707 1.1e-145 L Transposase and inactivated derivatives
MCOOGMHK_00708 1.6e-161
MCOOGMHK_00709 2.8e-188 nusA K Participates in both transcription termination and antitermination
MCOOGMHK_00710 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCOOGMHK_00711 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCOOGMHK_00712 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCOOGMHK_00713 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MCOOGMHK_00714 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCOOGMHK_00715 1.2e-106
MCOOGMHK_00717 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MCOOGMHK_00718 3.8e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCOOGMHK_00719 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MCOOGMHK_00720 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MCOOGMHK_00721 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MCOOGMHK_00723 2.7e-43 M Spy0128-like isopeptide containing domain
MCOOGMHK_00724 4.4e-42 M Spy0128-like isopeptide containing domain
MCOOGMHK_00725 0.0 crr G pts system, glucose-specific IIABC component
MCOOGMHK_00726 1.3e-151 arbG K CAT RNA binding domain
MCOOGMHK_00727 5.1e-212 I Diacylglycerol kinase catalytic domain
MCOOGMHK_00728 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MCOOGMHK_00729 4.7e-238 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCOOGMHK_00731 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MCOOGMHK_00733 1.2e-94
MCOOGMHK_00734 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCOOGMHK_00735 7.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
MCOOGMHK_00736 6e-143 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MCOOGMHK_00738 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCOOGMHK_00739 9.2e-126 degU K helix_turn_helix, Lux Regulon
MCOOGMHK_00740 8.9e-273 tcsS3 KT PspC domain
MCOOGMHK_00741 1.9e-290 pspC KT PspC domain
MCOOGMHK_00742 2.1e-129
MCOOGMHK_00743 4.3e-112 S Protein of unknown function (DUF4125)
MCOOGMHK_00744 0.0 S Domain of unknown function (DUF4037)
MCOOGMHK_00745 1.2e-216 araJ EGP Major facilitator Superfamily
MCOOGMHK_00747 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MCOOGMHK_00748 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MCOOGMHK_00749 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCOOGMHK_00750 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
MCOOGMHK_00751 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCOOGMHK_00752 2.6e-39
MCOOGMHK_00753 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MCOOGMHK_00754 9.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
MCOOGMHK_00755 1.7e-105 M NlpC/P60 family
MCOOGMHK_00756 7.8e-191 T Universal stress protein family
MCOOGMHK_00757 8.5e-72 attW O OsmC-like protein
MCOOGMHK_00758 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCOOGMHK_00759 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
MCOOGMHK_00760 6.2e-96 ptpA 3.1.3.48 T low molecular weight
MCOOGMHK_00761 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MCOOGMHK_00762 9.4e-23 azlD E Branched-chain amino acid transport protein (AzlD)
MCOOGMHK_00763 1.3e-111 vex2 V ABC transporter, ATP-binding protein
MCOOGMHK_00764 3.2e-212 vex1 V Efflux ABC transporter, permease protein
MCOOGMHK_00765 4.7e-220 vex3 V ABC transporter permease
MCOOGMHK_00767 6.6e-172
MCOOGMHK_00768 1.6e-108 ytrE V ABC transporter
MCOOGMHK_00769 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
MCOOGMHK_00770 2.2e-95
MCOOGMHK_00771 3.9e-119 K Transcriptional regulatory protein, C terminal
MCOOGMHK_00772 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCOOGMHK_00773 3e-183 lacR K Transcriptional regulator, LacI family
MCOOGMHK_00774 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
MCOOGMHK_00775 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCOOGMHK_00776 8.6e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
MCOOGMHK_00778 1.6e-154 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCOOGMHK_00779 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MCOOGMHK_00780 2.6e-68 S Domain of unknown function (DUF4190)
MCOOGMHK_00783 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MCOOGMHK_00784 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
MCOOGMHK_00785 4.3e-273 S AI-2E family transporter
MCOOGMHK_00786 1.3e-232 epsG M Glycosyl transferase family 21
MCOOGMHK_00787 1.7e-168 natA V ATPases associated with a variety of cellular activities
MCOOGMHK_00788 5e-309
MCOOGMHK_00789 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MCOOGMHK_00790 1.1e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCOOGMHK_00791 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MCOOGMHK_00792 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCOOGMHK_00793 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MCOOGMHK_00794 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MCOOGMHK_00795 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MCOOGMHK_00796 1.3e-77 S Protein of unknown function (DUF3180)
MCOOGMHK_00797 7.1e-172 tesB I Thioesterase-like superfamily
MCOOGMHK_00798 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
MCOOGMHK_00799 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
MCOOGMHK_00800 2.1e-45 T response regulator
MCOOGMHK_00801 2.5e-43 K response regulator
MCOOGMHK_00802 1.2e-97 S Domain of unknown function (DUF4825)
MCOOGMHK_00804 3.2e-25 fic D Fic/DOC family
MCOOGMHK_00805 5.6e-67 fic D Fic/DOC family
MCOOGMHK_00806 2e-07
MCOOGMHK_00807 1.4e-89 S Protein of unknown function (DUF3990)
MCOOGMHK_00808 2.8e-37 S Protein of unknown function (DUF3791)
MCOOGMHK_00809 9.6e-15 M domain, Protein
MCOOGMHK_00810 4.7e-48 M domain, Protein
MCOOGMHK_00811 4.6e-35
MCOOGMHK_00812 1.8e-59
MCOOGMHK_00814 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCOOGMHK_00815 6.3e-17 S Protein of unknown function (DUF979)
MCOOGMHK_00816 1.3e-55 S DUF218 domain
MCOOGMHK_00818 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
MCOOGMHK_00819 1.1e-158 I alpha/beta hydrolase fold
MCOOGMHK_00820 1.2e-55 EGP Major facilitator Superfamily
MCOOGMHK_00821 7.8e-299 S ATPases associated with a variety of cellular activities
MCOOGMHK_00822 3.7e-179 glkA 2.7.1.2 G ROK family
MCOOGMHK_00823 4e-10 K Winged helix DNA-binding domain
MCOOGMHK_00824 6.8e-73 EGP Major facilitator superfamily
MCOOGMHK_00825 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
MCOOGMHK_00826 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MCOOGMHK_00827 1.7e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
MCOOGMHK_00828 1.9e-26 L Transposase
MCOOGMHK_00830 3.4e-147 S Sulfite exporter TauE/SafE
MCOOGMHK_00831 1.1e-140 V FtsX-like permease family
MCOOGMHK_00833 4.2e-164 EG EamA-like transporter family
MCOOGMHK_00834 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MCOOGMHK_00835 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
MCOOGMHK_00836 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MCOOGMHK_00837 1.5e-108
MCOOGMHK_00838 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MCOOGMHK_00839 1.3e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MCOOGMHK_00840 2.6e-163 glcU G Sugar transport protein
MCOOGMHK_00841 2.1e-196 K helix_turn_helix, arabinose operon control protein
MCOOGMHK_00843 3.9e-36 rpmE J Binds the 23S rRNA
MCOOGMHK_00844 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCOOGMHK_00845 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCOOGMHK_00846 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MCOOGMHK_00847 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
MCOOGMHK_00848 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MCOOGMHK_00849 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MCOOGMHK_00850 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MCOOGMHK_00851 1.2e-24 KT Transcriptional regulatory protein, C terminal
MCOOGMHK_00852 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MCOOGMHK_00853 9e-161 supH S Sucrose-6F-phosphate phosphohydrolase
MCOOGMHK_00854 3e-270 recD2 3.6.4.12 L PIF1-like helicase
MCOOGMHK_00857 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCOOGMHK_00858 2.4e-170
MCOOGMHK_00859 2.1e-97 L Single-strand binding protein family
MCOOGMHK_00860 0.0 pepO 3.4.24.71 O Peptidase family M13
MCOOGMHK_00861 1.5e-121 S Short repeat of unknown function (DUF308)
MCOOGMHK_00862 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
MCOOGMHK_00863 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MCOOGMHK_00864 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MCOOGMHK_00865 7.1e-197 yghZ C Aldo/keto reductase family
MCOOGMHK_00866 1.7e-79 EGP Major Facilitator Superfamily
MCOOGMHK_00867 3.6e-93 K acetyltransferase
MCOOGMHK_00868 0.0 ctpE P E1-E2 ATPase
MCOOGMHK_00869 0.0 macB_2 V ATPases associated with a variety of cellular activities
MCOOGMHK_00870 8.1e-227 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MCOOGMHK_00871 4.7e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MCOOGMHK_00872 4.1e-231 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCOOGMHK_00873 2.2e-243 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MCOOGMHK_00874 1.8e-127 XK27_08050 O prohibitin homologues
MCOOGMHK_00875 3e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MCOOGMHK_00876 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MCOOGMHK_00877 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCOOGMHK_00878 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MCOOGMHK_00879 5.2e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
MCOOGMHK_00880 1.5e-47 3.1.21.3 V Type I restriction modification DNA specificity domain
MCOOGMHK_00881 2e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
MCOOGMHK_00882 2.9e-107 L Belongs to the 'phage' integrase family
MCOOGMHK_00883 2.6e-16 K Helix-turn-helix domain
MCOOGMHK_00884 3.4e-18 S Protein of unknown function (DUF2442)
MCOOGMHK_00885 3.3e-22 L Helix-turn-helix domain
MCOOGMHK_00886 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
MCOOGMHK_00887 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MCOOGMHK_00888 2.9e-190 K Periplasmic binding protein domain
MCOOGMHK_00889 2.5e-124 G ABC transporter permease
MCOOGMHK_00890 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCOOGMHK_00891 3.8e-66 G carbohydrate transport
MCOOGMHK_00892 1.7e-276 G Bacterial extracellular solute-binding protein
MCOOGMHK_00893 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MCOOGMHK_00894 1.3e-309 E ABC transporter, substrate-binding protein, family 5
MCOOGMHK_00895 4.6e-169 P Binding-protein-dependent transport system inner membrane component
MCOOGMHK_00896 1.6e-161 EP Binding-protein-dependent transport system inner membrane component
MCOOGMHK_00897 2.6e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MCOOGMHK_00898 1.3e-154 sapF E ATPases associated with a variety of cellular activities
MCOOGMHK_00899 5.4e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCOOGMHK_00900 4.4e-109
MCOOGMHK_00901 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MCOOGMHK_00902 4.1e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCOOGMHK_00903 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MCOOGMHK_00904 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCOOGMHK_00905 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MCOOGMHK_00906 2.6e-269 yhdG E aromatic amino acid transport protein AroP K03293
MCOOGMHK_00907 1.7e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCOOGMHK_00908 1.5e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MCOOGMHK_00909 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCOOGMHK_00910 3.5e-160 K Helix-turn-helix domain, rpiR family
MCOOGMHK_00911 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCOOGMHK_00912 1.4e-44 S Memo-like protein
MCOOGMHK_00914 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCOOGMHK_00915 2.9e-179 adh3 C Zinc-binding dehydrogenase
MCOOGMHK_00916 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MCOOGMHK_00917 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MCOOGMHK_00918 4.3e-73 zur P Belongs to the Fur family
MCOOGMHK_00919 9.8e-45
MCOOGMHK_00920 7.7e-154 S TIGRFAM TIGR03943 family protein
MCOOGMHK_00921 1.4e-201 ycgR S Predicted permease
MCOOGMHK_00922 1.9e-22 J Ribosomal L32p protein family
MCOOGMHK_00923 8.2e-15 rpmJ J Ribosomal protein L36
MCOOGMHK_00924 7.4e-42 rpmE2 J Ribosomal protein L31
MCOOGMHK_00925 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCOOGMHK_00926 2.3e-47 rpmB J Ribosomal L28 family
MCOOGMHK_00927 8.7e-139 S cobalamin synthesis protein
MCOOGMHK_00928 3.3e-161 P Zinc-uptake complex component A periplasmic
MCOOGMHK_00929 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MCOOGMHK_00930 1.7e-246 S Putative esterase
MCOOGMHK_00931 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MCOOGMHK_00932 9.4e-239 purD 6.3.4.13 F Belongs to the GARS family
MCOOGMHK_00933 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MCOOGMHK_00934 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MCOOGMHK_00935 5.5e-305 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MCOOGMHK_00936 2e-32
MCOOGMHK_00937 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCOOGMHK_00938 8.9e-33 K DNA-binding transcription factor activity
MCOOGMHK_00939 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MCOOGMHK_00940 2.1e-93 S Protein of unknown function (DUF4230)
MCOOGMHK_00941 3.3e-110
MCOOGMHK_00942 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MCOOGMHK_00943 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MCOOGMHK_00944 3.7e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MCOOGMHK_00945 0.0 M Parallel beta-helix repeats
MCOOGMHK_00946 1.6e-227 M Glycosyl transferase 4-like domain
MCOOGMHK_00947 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
MCOOGMHK_00949 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCOOGMHK_00950 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCOOGMHK_00951 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCOOGMHK_00952 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCOOGMHK_00953 0.0 S Esterase-like activity of phytase
MCOOGMHK_00954 1e-191 EGP Transmembrane secretion effector
MCOOGMHK_00956 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCOOGMHK_00957 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCOOGMHK_00958 1.2e-238 carA 6.3.5.5 F Belongs to the CarA family
MCOOGMHK_00959 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MCOOGMHK_00960 4.4e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MCOOGMHK_00961 0.0 S Protein of unknown function DUF262
MCOOGMHK_00962 9.1e-116 K helix_turn_helix, Lux Regulon
MCOOGMHK_00963 1.7e-265 T Histidine kinase
MCOOGMHK_00964 1e-97 S Domain of unknown function (DUF5067)
MCOOGMHK_00965 6.6e-132 ybhL S Belongs to the BI1 family
MCOOGMHK_00966 7.5e-172 ydeD EG EamA-like transporter family
MCOOGMHK_00967 2.3e-72 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MCOOGMHK_00968 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MCOOGMHK_00969 6.1e-129 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCOOGMHK_00970 1.2e-137 fic D Fic/DOC family
MCOOGMHK_00971 0.0 ftsK D FtsK SpoIIIE family protein
MCOOGMHK_00972 5.4e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCOOGMHK_00973 6.5e-96 cinA 3.5.1.42 S Belongs to the CinA family
MCOOGMHK_00974 7.3e-81 K Helix-turn-helix XRE-family like proteins
MCOOGMHK_00975 3.7e-40 S Protein of unknown function (DUF3046)
MCOOGMHK_00976 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCOOGMHK_00977 2.9e-87 recX S Modulates RecA activity
MCOOGMHK_00978 1e-07
MCOOGMHK_00979 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCOOGMHK_00980 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCOOGMHK_00981 3.6e-25 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCOOGMHK_00982 6.4e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MCOOGMHK_00983 1.5e-109
MCOOGMHK_00984 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
MCOOGMHK_00985 0.0 pknL 2.7.11.1 KLT PASTA
MCOOGMHK_00986 1e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MCOOGMHK_00987 1e-122
MCOOGMHK_00988 4.5e-179 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCOOGMHK_00989 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MCOOGMHK_00990 8.9e-278 aspA 4.3.1.1 E Fumarase C C-terminus
MCOOGMHK_00991 3.2e-45 S Protein of unknown function (DUF2975)
MCOOGMHK_00992 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
MCOOGMHK_00993 0.0 lhr L DEAD DEAH box helicase
MCOOGMHK_00994 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MCOOGMHK_00995 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
MCOOGMHK_00996 1.4e-187 S Protein of unknown function (DUF3071)
MCOOGMHK_00997 1.4e-47 S Domain of unknown function (DUF4193)
MCOOGMHK_00998 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MCOOGMHK_00999 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCOOGMHK_01000 2.7e-28
MCOOGMHK_01001 1.4e-12
MCOOGMHK_01002 2.5e-208 E Belongs to the peptidase S1B family
MCOOGMHK_01003 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
MCOOGMHK_01004 1.1e-49 relB L RelB antitoxin
MCOOGMHK_01005 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCOOGMHK_01006 4.6e-165 S Sucrose-6F-phosphate phosphohydrolase
MCOOGMHK_01007 3.3e-87 P ABC-type metal ion transport system permease component
MCOOGMHK_01008 2.7e-224 S Peptidase dimerisation domain
MCOOGMHK_01009 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MCOOGMHK_01010 6.4e-40
MCOOGMHK_01011 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MCOOGMHK_01012 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCOOGMHK_01013 4.4e-114 S Protein of unknown function (DUF3000)
MCOOGMHK_01014 2.7e-249 rnd 3.1.13.5 J 3'-5' exonuclease
MCOOGMHK_01015 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCOOGMHK_01016 2e-253 clcA_2 P Voltage gated chloride channel
MCOOGMHK_01017 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCOOGMHK_01018 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCOOGMHK_01019 1.3e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCOOGMHK_01022 1.3e-234 patB 4.4.1.8 E Aminotransferase, class I II
MCOOGMHK_01023 1.3e-224 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MCOOGMHK_01024 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
MCOOGMHK_01025 4.4e-118 safC S O-methyltransferase
MCOOGMHK_01026 1.1e-181 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MCOOGMHK_01027 1.1e-70 yraN L Belongs to the UPF0102 family
MCOOGMHK_01028 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
MCOOGMHK_01029 4.1e-281 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MCOOGMHK_01030 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MCOOGMHK_01031 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MCOOGMHK_01032 1.6e-157 S Putative ABC-transporter type IV
MCOOGMHK_01033 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
MCOOGMHK_01035 4e-162 V ABC transporter, ATP-binding protein
MCOOGMHK_01036 0.0 MV MacB-like periplasmic core domain
MCOOGMHK_01037 0.0 phoN I PAP2 superfamily
MCOOGMHK_01038 2.8e-129 K helix_turn_helix, Lux Regulon
MCOOGMHK_01039 0.0 tcsS2 T Histidine kinase
MCOOGMHK_01040 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
MCOOGMHK_01041 2.7e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCOOGMHK_01042 1.6e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MCOOGMHK_01043 2.7e-146 P NLPA lipoprotein
MCOOGMHK_01044 3.8e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
MCOOGMHK_01045 7.8e-183 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MCOOGMHK_01046 7.5e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCOOGMHK_01047 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01048 8.4e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
MCOOGMHK_01049 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCOOGMHK_01050 6.3e-246 XK27_00240 K Fic/DOC family
MCOOGMHK_01051 2.3e-120 E Psort location Cytoplasmic, score 8.87
MCOOGMHK_01052 5.6e-59 yccF S Inner membrane component domain
MCOOGMHK_01053 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
MCOOGMHK_01054 2.5e-66 S Cupin 2, conserved barrel domain protein
MCOOGMHK_01055 1.1e-255 KLT Protein tyrosine kinase
MCOOGMHK_01056 4.5e-79 K Psort location Cytoplasmic, score
MCOOGMHK_01057 5.9e-148
MCOOGMHK_01058 2.7e-22
MCOOGMHK_01059 5.5e-199 S Short C-terminal domain
MCOOGMHK_01060 2.7e-87 S Helix-turn-helix
MCOOGMHK_01061 1.1e-65 S Zincin-like metallopeptidase
MCOOGMHK_01062 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MCOOGMHK_01063 2e-39
MCOOGMHK_01064 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MCOOGMHK_01065 2.1e-125 ypfH S Phospholipase/Carboxylesterase
MCOOGMHK_01066 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCOOGMHK_01068 1.2e-288 2.4.1.166 GT2 M Glycosyltransferase like family 2
MCOOGMHK_01069 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
MCOOGMHK_01070 3.5e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MCOOGMHK_01071 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
MCOOGMHK_01072 1.6e-54 estB S Phospholipase/Carboxylesterase
MCOOGMHK_01073 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
MCOOGMHK_01074 1.4e-237 rutG F Permease family
MCOOGMHK_01075 6.9e-83 K AraC-like ligand binding domain
MCOOGMHK_01077 3e-53 IQ oxidoreductase activity
MCOOGMHK_01078 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
MCOOGMHK_01079 3.4e-135 ybbL V ATPases associated with a variety of cellular activities
MCOOGMHK_01080 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCOOGMHK_01081 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCOOGMHK_01082 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MCOOGMHK_01083 5.1e-87
MCOOGMHK_01084 1.1e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MCOOGMHK_01085 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MCOOGMHK_01086 3.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MCOOGMHK_01087 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MCOOGMHK_01088 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCOOGMHK_01089 3.2e-84 argR K Regulates arginine biosynthesis genes
MCOOGMHK_01090 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MCOOGMHK_01091 1.5e-40 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MCOOGMHK_01092 1.9e-178 L Phage integrase family
MCOOGMHK_01093 2.4e-30
MCOOGMHK_01094 1.2e-154 S Domain of unknown function (DUF4357)
MCOOGMHK_01095 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MCOOGMHK_01096 1.1e-106 3.1.21.3 V type I restriction modification DNA specificity domain
MCOOGMHK_01097 4.3e-270 K Putative DNA-binding domain
MCOOGMHK_01098 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MCOOGMHK_01099 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
MCOOGMHK_01100 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MCOOGMHK_01101 3.5e-143 S Putative ABC-transporter type IV
MCOOGMHK_01102 1.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCOOGMHK_01103 3.6e-159 L Tetratricopeptide repeat
MCOOGMHK_01104 7.3e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MCOOGMHK_01106 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MCOOGMHK_01107 1.6e-99
MCOOGMHK_01108 6.8e-116 trkA P TrkA-N domain
MCOOGMHK_01109 9.5e-235 trkB P Cation transport protein
MCOOGMHK_01110 4.8e-182 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCOOGMHK_01111 3.5e-292 recN L May be involved in recombinational repair of damaged DNA
MCOOGMHK_01112 2e-123 S Haloacid dehalogenase-like hydrolase
MCOOGMHK_01113 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MCOOGMHK_01114 2.7e-177 V ATPases associated with a variety of cellular activities
MCOOGMHK_01115 2.8e-126 S ABC-2 family transporter protein
MCOOGMHK_01116 4e-122 S ABC-2 family transporter protein
MCOOGMHK_01117 1.9e-283 thrC 4.2.3.1 E Threonine synthase N terminus
MCOOGMHK_01118 1.4e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MCOOGMHK_01119 6.8e-93
MCOOGMHK_01120 4.7e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCOOGMHK_01121 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCOOGMHK_01123 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCOOGMHK_01124 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCOOGMHK_01125 2.7e-137 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MCOOGMHK_01126 1.3e-78 S Bacterial PH domain
MCOOGMHK_01127 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MCOOGMHK_01129 3e-93
MCOOGMHK_01130 5e-133 C Putative TM nitroreductase
MCOOGMHK_01131 5.9e-142 yijF S Domain of unknown function (DUF1287)
MCOOGMHK_01132 7.8e-70 pdxH S Pfam:Pyridox_oxidase
MCOOGMHK_01133 1.3e-54 KT RESPONSE REGULATOR receiver
MCOOGMHK_01134 1.4e-192 V VanZ like family
MCOOGMHK_01135 1.1e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MCOOGMHK_01136 1.5e-95 ypjC S Putative ABC-transporter type IV
MCOOGMHK_01137 3.5e-10 CE Amino acid permease
MCOOGMHK_01138 1.2e-147 3.6.4.12
MCOOGMHK_01140 5.2e-101 EGP Major facilitator Superfamily
MCOOGMHK_01141 3e-28 EGP Major facilitator Superfamily
MCOOGMHK_01142 1.3e-163 rpoC M heme binding
MCOOGMHK_01143 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCOOGMHK_01144 4.8e-128
MCOOGMHK_01145 2.9e-133 S SOS response associated peptidase (SRAP)
MCOOGMHK_01146 1.6e-76 qseC 2.7.13.3 T Histidine kinase
MCOOGMHK_01147 1.2e-185 S Acetyltransferase (GNAT) domain
MCOOGMHK_01149 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MCOOGMHK_01150 7e-56 K Transcriptional regulator
MCOOGMHK_01151 4.5e-88 MA20_25245 K FR47-like protein
MCOOGMHK_01152 1.2e-114 ydaF_1 J Acetyltransferase (GNAT) domain
MCOOGMHK_01153 1.1e-62 yeaO K Protein of unknown function, DUF488
MCOOGMHK_01154 9e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MCOOGMHK_01155 8.8e-284 S Psort location Cytoplasmic, score 8.87
MCOOGMHK_01156 1.7e-108 S Domain of unknown function (DUF4194)
MCOOGMHK_01157 0.0 S Psort location Cytoplasmic, score 8.87
MCOOGMHK_01158 3.4e-299 E Serine carboxypeptidase
MCOOGMHK_01159 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MCOOGMHK_01160 3.7e-171 corA P CorA-like Mg2+ transporter protein
MCOOGMHK_01161 2.6e-169 ET Bacterial periplasmic substrate-binding proteins
MCOOGMHK_01162 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCOOGMHK_01163 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MCOOGMHK_01164 0.0 comE S Competence protein
MCOOGMHK_01165 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
MCOOGMHK_01166 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MCOOGMHK_01167 1.5e-158 yeaZ 2.3.1.234 O Glycoprotease family
MCOOGMHK_01168 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MCOOGMHK_01169 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCOOGMHK_01171 7e-170 M Peptidase family M23
MCOOGMHK_01172 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MCOOGMHK_01173 3.2e-276 G ABC transporter substrate-binding protein
MCOOGMHK_01174 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MCOOGMHK_01175 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
MCOOGMHK_01176 5.7e-91
MCOOGMHK_01177 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MCOOGMHK_01178 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCOOGMHK_01179 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MCOOGMHK_01180 2.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCOOGMHK_01181 1e-127 3.2.1.8 S alpha beta
MCOOGMHK_01182 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MCOOGMHK_01183 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCOOGMHK_01184 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MCOOGMHK_01185 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MCOOGMHK_01186 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MCOOGMHK_01187 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MCOOGMHK_01188 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCOOGMHK_01189 3.7e-208 G Bacterial extracellular solute-binding protein
MCOOGMHK_01190 1.2e-19 G Bacterial extracellular solute-binding protein
MCOOGMHK_01191 1.4e-173 G Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01192 1e-168 G ABC transporter permease
MCOOGMHK_01193 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MCOOGMHK_01194 1.5e-177 2.7.1.2 GK ROK family
MCOOGMHK_01195 6.4e-218 GK ROK family
MCOOGMHK_01196 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MCOOGMHK_01197 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MCOOGMHK_01198 1.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MCOOGMHK_01199 8.9e-303 ybiT S ABC transporter
MCOOGMHK_01200 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MCOOGMHK_01201 1.1e-230 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCOOGMHK_01202 3.9e-37 K Transcriptional regulatory protein, C terminal
MCOOGMHK_01203 1.9e-41 K Transcriptional regulatory protein, C terminal
MCOOGMHK_01204 7.1e-28 V MacB-like periplasmic core domain
MCOOGMHK_01205 6.1e-77
MCOOGMHK_01206 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCOOGMHK_01207 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCOOGMHK_01208 4.3e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MCOOGMHK_01209 1.5e-177 rapZ S Displays ATPase and GTPase activities
MCOOGMHK_01210 3.1e-173 whiA K May be required for sporulation
MCOOGMHK_01211 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MCOOGMHK_01212 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCOOGMHK_01213 8e-33 secG U Preprotein translocase SecG subunit
MCOOGMHK_01214 5.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MCOOGMHK_01215 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
MCOOGMHK_01216 3.1e-243 mepA_6 V MatE
MCOOGMHK_01218 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
MCOOGMHK_01219 1.2e-143 yoaK S Protein of unknown function (DUF1275)
MCOOGMHK_01220 2.3e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MCOOGMHK_01221 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MCOOGMHK_01222 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCOOGMHK_01223 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCOOGMHK_01224 7.1e-160 G Fructosamine kinase
MCOOGMHK_01225 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MCOOGMHK_01226 2.8e-156 S PAC2 family
MCOOGMHK_01230 2.6e-262
MCOOGMHK_01233 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCOOGMHK_01234 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCOOGMHK_01235 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
MCOOGMHK_01236 1e-131 yebC K transcriptional regulatory protein
MCOOGMHK_01237 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MCOOGMHK_01238 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCOOGMHK_01239 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCOOGMHK_01240 2.6e-44 yajC U Preprotein translocase subunit
MCOOGMHK_01241 2.1e-100 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCOOGMHK_01242 2.5e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MCOOGMHK_01243 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MCOOGMHK_01244 2.7e-244
MCOOGMHK_01245 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MCOOGMHK_01246 5.7e-30
MCOOGMHK_01247 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MCOOGMHK_01248 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MCOOGMHK_01249 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MCOOGMHK_01250 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MCOOGMHK_01251 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MCOOGMHK_01252 5.2e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCOOGMHK_01253 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MCOOGMHK_01254 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MCOOGMHK_01255 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MCOOGMHK_01256 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCOOGMHK_01257 1.2e-172 S Bacterial protein of unknown function (DUF881)
MCOOGMHK_01258 2.6e-31 sbp S Protein of unknown function (DUF1290)
MCOOGMHK_01259 2.6e-141 S Bacterial protein of unknown function (DUF881)
MCOOGMHK_01260 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MCOOGMHK_01261 2.7e-120 K helix_turn_helix, mercury resistance
MCOOGMHK_01262 7.3e-62
MCOOGMHK_01264 1.3e-96 L DNA integration
MCOOGMHK_01265 4.7e-125 S GyrI-like small molecule binding domain
MCOOGMHK_01266 4.2e-35 pgp 3.1.3.18 S HAD-hyrolase-like
MCOOGMHK_01267 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MCOOGMHK_01268 0.0 helY L DEAD DEAH box helicase
MCOOGMHK_01269 7.7e-52
MCOOGMHK_01270 0.0 pafB K WYL domain
MCOOGMHK_01271 6.3e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MCOOGMHK_01273 1.2e-88 dkgB S Oxidoreductase, aldo keto reductase family protein
MCOOGMHK_01274 7.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
MCOOGMHK_01275 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCOOGMHK_01276 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCOOGMHK_01277 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MCOOGMHK_01278 2e-91 T Domain of unknown function (DUF4234)
MCOOGMHK_01279 9.3e-101 K Bacterial regulatory proteins, tetR family
MCOOGMHK_01280 1.6e-18
MCOOGMHK_01281 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
MCOOGMHK_01282 1.4e-40 K Helix-turn-helix
MCOOGMHK_01283 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
MCOOGMHK_01284 1.1e-65 4.1.1.44 S Cupin domain
MCOOGMHK_01285 4e-176 S Membrane transport protein
MCOOGMHK_01286 3.8e-93 laaE K Transcriptional regulator PadR-like family
MCOOGMHK_01287 7.9e-134 magIII L endonuclease III
MCOOGMHK_01288 8.1e-131 S Enoyl-(Acyl carrier protein) reductase
MCOOGMHK_01289 5.2e-243 vbsD V MatE
MCOOGMHK_01290 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MCOOGMHK_01291 1.9e-15 KLT Protein tyrosine kinase
MCOOGMHK_01293 9.4e-145
MCOOGMHK_01294 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MCOOGMHK_01295 1e-16 K MerR family regulatory protein
MCOOGMHK_01296 1.1e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCOOGMHK_01297 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCOOGMHK_01298 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MCOOGMHK_01299 2.6e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MCOOGMHK_01300 4.7e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCOOGMHK_01301 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MCOOGMHK_01302 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MCOOGMHK_01303 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MCOOGMHK_01305 9e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MCOOGMHK_01306 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MCOOGMHK_01310 2.2e-127 3.5.1.28 M NLP P60 protein
MCOOGMHK_01311 6.5e-67 S SPP1 phage holin
MCOOGMHK_01312 1.3e-69
MCOOGMHK_01313 6.2e-50 MU outer membrane autotransporter barrel domain protein
MCOOGMHK_01314 4e-214
MCOOGMHK_01315 2.8e-64
MCOOGMHK_01316 0.0 S Prophage endopeptidase tail
MCOOGMHK_01317 1.8e-147 S phage tail
MCOOGMHK_01318 0.0 S Phage-related minor tail protein
MCOOGMHK_01319 6.3e-53
MCOOGMHK_01320 7.7e-83
MCOOGMHK_01321 3.6e-94
MCOOGMHK_01322 4.9e-72
MCOOGMHK_01323 6.1e-73
MCOOGMHK_01324 1.3e-78
MCOOGMHK_01325 2.2e-90
MCOOGMHK_01326 8.1e-65
MCOOGMHK_01327 3.8e-176 S Phage capsid family
MCOOGMHK_01328 3.7e-78
MCOOGMHK_01330 1.1e-43
MCOOGMHK_01331 7.4e-241
MCOOGMHK_01332 5.5e-280 S Phage portal protein, SPP1 Gp6-like
MCOOGMHK_01333 0.0 S Terminase
MCOOGMHK_01334 4.8e-69
MCOOGMHK_01335 6.7e-115 S Bifunctional DNA primase/polymerase, N-terminal
MCOOGMHK_01336 8.1e-66
MCOOGMHK_01339 3.2e-32 K Transcriptional regulator
MCOOGMHK_01341 1.5e-73 S HicB_like antitoxin of bacterial toxin-antitoxin system
MCOOGMHK_01342 1.3e-34 N HicA toxin of bacterial toxin-antitoxin,
MCOOGMHK_01343 9.7e-143
MCOOGMHK_01345 3e-50
MCOOGMHK_01347 1.9e-109 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MCOOGMHK_01348 2.6e-81 V HNH endonuclease
MCOOGMHK_01349 1.5e-26
MCOOGMHK_01350 1.9e-145 K Transcriptional regulator
MCOOGMHK_01351 1.4e-275 K ParB-like nuclease domain
MCOOGMHK_01352 8.6e-93 ssb1 L Single-strand binding protein family
MCOOGMHK_01354 5.6e-36
MCOOGMHK_01356 2.2e-37
MCOOGMHK_01359 2e-122 K BRO family, N-terminal domain
MCOOGMHK_01360 3.3e-22
MCOOGMHK_01361 8.2e-53
MCOOGMHK_01362 1.9e-34
MCOOGMHK_01363 1.2e-54
MCOOGMHK_01364 2.5e-104 S Virulence protein RhuM family
MCOOGMHK_01365 3.8e-50
MCOOGMHK_01366 6e-16
MCOOGMHK_01367 5.1e-45 E IrrE N-terminal-like domain
MCOOGMHK_01368 3.9e-242 int L Phage integrase, N-terminal SAM-like domain
MCOOGMHK_01369 2e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
MCOOGMHK_01370 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MCOOGMHK_01371 3e-178 I alpha/beta hydrolase fold
MCOOGMHK_01372 1.4e-23 rarD S EamA-like transporter family
MCOOGMHK_01373 4e-71 rarD 3.4.17.13 E Rard protein
MCOOGMHK_01374 1.1e-29
MCOOGMHK_01375 0.0 S Protein of unknown function DUF262
MCOOGMHK_01376 1e-109 S AAA-like domain
MCOOGMHK_01377 1.2e-88 S AAA-like domain
MCOOGMHK_01378 2.5e-56 S SIR2-like domain
MCOOGMHK_01379 2.8e-182 3.1.21.4 V Type III restriction enzyme res subunit
MCOOGMHK_01380 6.9e-56 L Eco57I restriction-modification methylase
MCOOGMHK_01381 1.9e-38 L Eco57I restriction-modification methylase
MCOOGMHK_01382 0.0 KL Type III restriction enzyme res subunit
MCOOGMHK_01383 5.1e-22 XK26_04895
MCOOGMHK_01384 2.3e-31 XK26_04895
MCOOGMHK_01385 1.6e-28
MCOOGMHK_01386 9.3e-181 L Transposase
MCOOGMHK_01387 1.7e-61 S Short C-terminal domain
MCOOGMHK_01388 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MCOOGMHK_01389 1.3e-113 S Sel1-like repeats.
MCOOGMHK_01390 1.5e-158 ybeM S Carbon-nitrogen hydrolase
MCOOGMHK_01391 1.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MCOOGMHK_01392 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MCOOGMHK_01393 3.6e-82
MCOOGMHK_01394 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MCOOGMHK_01395 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MCOOGMHK_01396 0.0 tetP J Elongation factor G, domain IV
MCOOGMHK_01397 1.4e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MCOOGMHK_01398 3.4e-12 S Membrane
MCOOGMHK_01399 1.5e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
MCOOGMHK_01400 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCOOGMHK_01401 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
MCOOGMHK_01402 1.2e-135 S UPF0126 domain
MCOOGMHK_01403 2.7e-99 3.1.4.37 T RNA ligase
MCOOGMHK_01404 1.8e-46 S phosphoesterase or phosphohydrolase
MCOOGMHK_01405 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MCOOGMHK_01406 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MCOOGMHK_01407 1.8e-189 S alpha beta
MCOOGMHK_01408 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MCOOGMHK_01409 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MCOOGMHK_01410 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MCOOGMHK_01411 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCOOGMHK_01412 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCOOGMHK_01413 2.4e-251 corC S CBS domain
MCOOGMHK_01414 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCOOGMHK_01415 3.4e-197 phoH T PhoH-like protein
MCOOGMHK_01416 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MCOOGMHK_01417 4.9e-35 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCOOGMHK_01418 4.7e-83 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCOOGMHK_01420 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MCOOGMHK_01421 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MCOOGMHK_01422 1.2e-108 yitW S Iron-sulfur cluster assembly protein
MCOOGMHK_01423 2.6e-100 iscU C SUF system FeS assembly protein, NifU family
MCOOGMHK_01424 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MCOOGMHK_01425 2.4e-144 sufC O FeS assembly ATPase SufC
MCOOGMHK_01426 1.4e-234 sufD O FeS assembly protein SufD
MCOOGMHK_01427 3.6e-290 sufB O FeS assembly protein SufB
MCOOGMHK_01428 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCOOGMHK_01429 2.6e-07 3.4.22.70 M Sortase family
MCOOGMHK_01430 1.7e-120 K helix_turn_helix, Lux Regulon
MCOOGMHK_01431 1.9e-75
MCOOGMHK_01432 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MCOOGMHK_01433 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MCOOGMHK_01434 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MCOOGMHK_01435 6.3e-47 3.4.23.43 S Type IV leader peptidase family
MCOOGMHK_01436 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCOOGMHK_01437 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCOOGMHK_01438 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCOOGMHK_01439 1.1e-36
MCOOGMHK_01440 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MCOOGMHK_01441 9.8e-136 pgm3 G Phosphoglycerate mutase family
MCOOGMHK_01442 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
MCOOGMHK_01443 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCOOGMHK_01444 1.9e-128 lolD V ABC transporter
MCOOGMHK_01445 9.4e-212 V FtsX-like permease family
MCOOGMHK_01446 8.2e-64 S Domain of unknown function (DUF4418)
MCOOGMHK_01447 0.0 pcrA 3.6.4.12 L DNA helicase
MCOOGMHK_01448 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MCOOGMHK_01449 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCOOGMHK_01450 2e-239 pbuX F Permease family
MCOOGMHK_01452 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCOOGMHK_01454 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MCOOGMHK_01455 9e-40
MCOOGMHK_01456 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
MCOOGMHK_01457 5.9e-182 tnp7109-21 L Integrase core domain
MCOOGMHK_01458 8.6e-48 L Transposase
MCOOGMHK_01459 1.2e-64 D MobA/MobL family
MCOOGMHK_01460 1.2e-85
MCOOGMHK_01462 4.3e-205 L Transposase and inactivated derivatives IS30 family
MCOOGMHK_01463 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCOOGMHK_01464 3.4e-253 V ABC-2 family transporter protein
MCOOGMHK_01465 1.8e-226 V ABC-2 family transporter protein
MCOOGMHK_01466 2.9e-179 V ATPases associated with a variety of cellular activities
MCOOGMHK_01467 9.9e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MCOOGMHK_01468 7.8e-233 T Histidine kinase
MCOOGMHK_01469 3.1e-119 K helix_turn_helix, Lux Regulon
MCOOGMHK_01470 1.1e-115 MA20_27875 P Protein of unknown function DUF47
MCOOGMHK_01471 3.4e-189 pit P Phosphate transporter family
MCOOGMHK_01472 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MCOOGMHK_01473 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MCOOGMHK_01474 4.2e-09 S Domain of unknown function (DUF4339)
MCOOGMHK_01475 2.2e-80
MCOOGMHK_01476 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
MCOOGMHK_01477 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MCOOGMHK_01478 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCOOGMHK_01479 1.4e-275 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MCOOGMHK_01480 2.9e-108 3.4.13.21 E Peptidase family S51
MCOOGMHK_01482 9.7e-129
MCOOGMHK_01483 1.2e-100 3.5.1.124 S DJ-1/PfpI family
MCOOGMHK_01484 2.6e-163 1.1.1.346 S Aldo/keto reductase family
MCOOGMHK_01485 2.2e-72 K helix_turn_helix, mercury resistance
MCOOGMHK_01486 1.6e-73 K helix_turn_helix multiple antibiotic resistance protein
MCOOGMHK_01487 2e-16 U Major Facilitator Superfamily
MCOOGMHK_01488 4.8e-24 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
MCOOGMHK_01489 5.6e-43 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
MCOOGMHK_01490 2.5e-14
MCOOGMHK_01492 7.4e-217 ykiI
MCOOGMHK_01493 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MCOOGMHK_01494 1.2e-118 3.6.1.13 L NUDIX domain
MCOOGMHK_01495 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MCOOGMHK_01496 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCOOGMHK_01497 9.2e-120 pdtaR T Response regulator receiver domain protein
MCOOGMHK_01499 3.3e-109 aspA 3.6.1.13 L NUDIX domain
MCOOGMHK_01500 1.9e-272 pyk 2.7.1.40 G Pyruvate kinase
MCOOGMHK_01501 2.3e-102 terC P Integral membrane protein, TerC family
MCOOGMHK_01502 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCOOGMHK_01503 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCOOGMHK_01504 6.8e-241 rpsA J Ribosomal protein S1
MCOOGMHK_01505 2e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCOOGMHK_01506 9.6e-173 P Zinc-uptake complex component A periplasmic
MCOOGMHK_01507 1.8e-164 znuC P ATPases associated with a variety of cellular activities
MCOOGMHK_01508 4.3e-139 znuB U ABC 3 transport family
MCOOGMHK_01509 4.2e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MCOOGMHK_01510 5.1e-102 carD K CarD-like/TRCF domain
MCOOGMHK_01511 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MCOOGMHK_01512 1.9e-127 T Response regulator receiver domain protein
MCOOGMHK_01513 1.1e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCOOGMHK_01514 8.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
MCOOGMHK_01515 9.2e-130 ctsW S Phosphoribosyl transferase domain
MCOOGMHK_01516 5e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MCOOGMHK_01517 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MCOOGMHK_01518 2.2e-266
MCOOGMHK_01519 0.0 S Glycosyl transferase, family 2
MCOOGMHK_01520 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MCOOGMHK_01521 2.4e-270 K Cell envelope-related transcriptional attenuator domain
MCOOGMHK_01522 0.0 D FtsK/SpoIIIE family
MCOOGMHK_01523 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MCOOGMHK_01524 4.7e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCOOGMHK_01525 1.1e-140 yplQ S Haemolysin-III related
MCOOGMHK_01526 1e-107
MCOOGMHK_01528 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCOOGMHK_01529 2.2e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MCOOGMHK_01530 6.1e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MCOOGMHK_01531 1e-96
MCOOGMHK_01533 2.1e-54 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MCOOGMHK_01534 1e-119 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MCOOGMHK_01535 5.7e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MCOOGMHK_01536 2.5e-101 divIC D Septum formation initiator
MCOOGMHK_01537 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCOOGMHK_01538 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MCOOGMHK_01539 1.8e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MCOOGMHK_01540 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCOOGMHK_01541 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCOOGMHK_01542 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
MCOOGMHK_01543 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
MCOOGMHK_01544 1e-150 GM ABC-2 type transporter
MCOOGMHK_01545 1.9e-197 GM GDP-mannose 4,6 dehydratase
MCOOGMHK_01546 5e-128 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCOOGMHK_01549 1e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
MCOOGMHK_01550 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MCOOGMHK_01551 4e-206 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MCOOGMHK_01552 0.0 S Uncharacterised protein family (UPF0182)
MCOOGMHK_01553 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MCOOGMHK_01554 3.8e-196
MCOOGMHK_01555 3.2e-147 ytrE V ATPases associated with a variety of cellular activities
MCOOGMHK_01556 2.2e-191 V N-Acetylmuramoyl-L-alanine amidase
MCOOGMHK_01557 3e-259 argE E Peptidase dimerisation domain
MCOOGMHK_01558 5.5e-104 S Protein of unknown function (DUF3043)
MCOOGMHK_01559 5.2e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MCOOGMHK_01560 9.4e-144 S Domain of unknown function (DUF4191)
MCOOGMHK_01561 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
MCOOGMHK_01562 1.3e-18
MCOOGMHK_01564 5.1e-19
MCOOGMHK_01567 7.5e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_01568 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MCOOGMHK_01569 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCOOGMHK_01570 0.0 S Tetratricopeptide repeat
MCOOGMHK_01571 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MCOOGMHK_01572 8.2e-72 2.8.2.22 S Arylsulfotransferase Ig-like domain
MCOOGMHK_01573 3.4e-138 bioM P ATPases associated with a variety of cellular activities
MCOOGMHK_01574 2e-213 E Aminotransferase class I and II
MCOOGMHK_01575 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MCOOGMHK_01577 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCOOGMHK_01578 0.0 ecfA GP ABC transporter, ATP-binding protein
MCOOGMHK_01579 5.2e-257 EGP Major facilitator Superfamily
MCOOGMHK_01581 5.5e-256 rarA L Recombination factor protein RarA
MCOOGMHK_01582 0.0 L DEAD DEAH box helicase
MCOOGMHK_01583 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MCOOGMHK_01584 1.5e-197 gluD E Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01585 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01586 1.2e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
MCOOGMHK_01587 3.9e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MCOOGMHK_01588 8.2e-93 S Aminoacyl-tRNA editing domain
MCOOGMHK_01589 1.4e-63 K helix_turn_helix, Lux Regulon
MCOOGMHK_01590 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MCOOGMHK_01591 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MCOOGMHK_01592 1.7e-153 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MCOOGMHK_01593 7.7e-33 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MCOOGMHK_01597 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MCOOGMHK_01598 4.7e-185 uspA T Belongs to the universal stress protein A family
MCOOGMHK_01599 9.5e-192 S Protein of unknown function (DUF3027)
MCOOGMHK_01600 3.8e-66 cspB K 'Cold-shock' DNA-binding domain
MCOOGMHK_01601 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCOOGMHK_01602 1.6e-134 KT Response regulator receiver domain protein
MCOOGMHK_01603 1.2e-173
MCOOGMHK_01604 1.7e-10 S Proteins of 100 residues with WXG
MCOOGMHK_01605 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCOOGMHK_01606 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
MCOOGMHK_01607 9.9e-71 S LytR cell envelope-related transcriptional attenuator
MCOOGMHK_01608 4.4e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCOOGMHK_01609 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
MCOOGMHK_01610 1.5e-175 S Protein of unknown function DUF58
MCOOGMHK_01611 6.4e-94
MCOOGMHK_01612 6.8e-190 S von Willebrand factor (vWF) type A domain
MCOOGMHK_01613 1.6e-148 S von Willebrand factor (vWF) type A domain
MCOOGMHK_01614 2.7e-74
MCOOGMHK_01616 4.4e-291 S PGAP1-like protein
MCOOGMHK_01617 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MCOOGMHK_01618 0.0 S Lysylphosphatidylglycerol synthase TM region
MCOOGMHK_01619 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MCOOGMHK_01620 8.5e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MCOOGMHK_01621 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MCOOGMHK_01622 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
MCOOGMHK_01623 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MCOOGMHK_01624 0.0 arc O AAA ATPase forming ring-shaped complexes
MCOOGMHK_01625 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MCOOGMHK_01626 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCOOGMHK_01627 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCOOGMHK_01628 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCOOGMHK_01629 9.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCOOGMHK_01630 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCOOGMHK_01631 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MCOOGMHK_01632 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_01634 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MCOOGMHK_01635 3.9e-232 ctpE P E1-E2 ATPase
MCOOGMHK_01636 1.9e-220 ctpE P E1-E2 ATPase
MCOOGMHK_01637 2e-109
MCOOGMHK_01638 4.5e-249 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCOOGMHK_01639 6.1e-124 S Protein of unknown function (DUF3159)
MCOOGMHK_01640 2.1e-138 S Protein of unknown function (DUF3710)
MCOOGMHK_01641 1.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MCOOGMHK_01642 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
MCOOGMHK_01643 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MCOOGMHK_01644 0.0 oppD P Belongs to the ABC transporter superfamily
MCOOGMHK_01645 4.6e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
MCOOGMHK_01646 1.8e-176 appB EP Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01647 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MCOOGMHK_01648 7.3e-42
MCOOGMHK_01649 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MCOOGMHK_01650 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MCOOGMHK_01651 5.5e-92
MCOOGMHK_01652 0.0 typA T Elongation factor G C-terminus
MCOOGMHK_01653 8e-238 iscS1 2.8.1.7 E Aminotransferase class-V
MCOOGMHK_01654 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MCOOGMHK_01655 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MCOOGMHK_01656 3.7e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MCOOGMHK_01657 5.6e-149 nrtR 3.6.1.55 F NUDIX hydrolase
MCOOGMHK_01658 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCOOGMHK_01659 2.3e-148 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCOOGMHK_01660 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MCOOGMHK_01661 5.8e-180 xerD D recombinase XerD
MCOOGMHK_01662 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCOOGMHK_01663 2.1e-25 rpmI J Ribosomal protein L35
MCOOGMHK_01664 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCOOGMHK_01665 7.1e-68 S Spermine/spermidine synthase domain
MCOOGMHK_01666 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MCOOGMHK_01667 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCOOGMHK_01668 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCOOGMHK_01670 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MCOOGMHK_01671 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
MCOOGMHK_01672 2e-64
MCOOGMHK_01673 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MCOOGMHK_01674 4.2e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCOOGMHK_01675 6.8e-192 V Acetyltransferase (GNAT) domain
MCOOGMHK_01676 1.1e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
MCOOGMHK_01677 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
MCOOGMHK_01678 2.8e-128 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MCOOGMHK_01679 0.0 smc D Required for chromosome condensation and partitioning
MCOOGMHK_01680 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MCOOGMHK_01682 9.6e-97 3.6.1.55 F NUDIX domain
MCOOGMHK_01683 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MCOOGMHK_01684 0.0 P Belongs to the ABC transporter superfamily
MCOOGMHK_01685 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01686 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
MCOOGMHK_01687 2e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MCOOGMHK_01688 1.1e-213 nagA 3.5.1.25 G Amidohydrolase family
MCOOGMHK_01689 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCOOGMHK_01690 7e-217 GK ROK family
MCOOGMHK_01691 9.9e-132 cutC P Participates in the control of copper homeostasis
MCOOGMHK_01692 4.5e-222 GK ROK family
MCOOGMHK_01693 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
MCOOGMHK_01694 4.4e-236 G Major Facilitator Superfamily
MCOOGMHK_01695 2.3e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCOOGMHK_01697 1.3e-37
MCOOGMHK_01698 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
MCOOGMHK_01699 1.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
MCOOGMHK_01700 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCOOGMHK_01701 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MCOOGMHK_01702 2.7e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCOOGMHK_01703 1.8e-201 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCOOGMHK_01704 4e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCOOGMHK_01705 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCOOGMHK_01706 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MCOOGMHK_01707 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MCOOGMHK_01708 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCOOGMHK_01709 1.4e-89 mraZ K Belongs to the MraZ family
MCOOGMHK_01710 0.0 L DNA helicase
MCOOGMHK_01711 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MCOOGMHK_01712 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCOOGMHK_01713 1.5e-43 M Lysin motif
MCOOGMHK_01714 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCOOGMHK_01715 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCOOGMHK_01716 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MCOOGMHK_01717 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCOOGMHK_01718 3.9e-173
MCOOGMHK_01719 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MCOOGMHK_01720 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MCOOGMHK_01721 1.4e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MCOOGMHK_01722 1.1e-57 EGP Major facilitator Superfamily
MCOOGMHK_01723 1.4e-248 S Domain of unknown function (DUF5067)
MCOOGMHK_01724 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MCOOGMHK_01725 5.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
MCOOGMHK_01726 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MCOOGMHK_01727 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MCOOGMHK_01728 5.9e-113
MCOOGMHK_01729 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MCOOGMHK_01730 1.2e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MCOOGMHK_01731 2.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MCOOGMHK_01732 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCOOGMHK_01733 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCOOGMHK_01735 1.2e-76 yneG S Domain of unknown function (DUF4186)
MCOOGMHK_01736 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
MCOOGMHK_01737 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
MCOOGMHK_01738 3.4e-202 K WYL domain
MCOOGMHK_01740 0.0 4.2.1.53 S MCRA family
MCOOGMHK_01741 1.6e-46 yhbY J CRS1_YhbY
MCOOGMHK_01742 7.6e-106 S zinc-ribbon domain
MCOOGMHK_01743 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MCOOGMHK_01744 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MCOOGMHK_01745 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MCOOGMHK_01746 9.6e-191 ywqG S Domain of unknown function (DUF1963)
MCOOGMHK_01747 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCOOGMHK_01748 4.3e-141 recO L Involved in DNA repair and RecF pathway recombination
MCOOGMHK_01749 4.7e-291 I acetylesterase activity
MCOOGMHK_01750 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MCOOGMHK_01751 1.2e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MCOOGMHK_01752 3.4e-198 2.7.11.1 NU Tfp pilus assembly protein FimV
MCOOGMHK_01754 4.6e-82
MCOOGMHK_01755 1.2e-145 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MCOOGMHK_01756 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MCOOGMHK_01757 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
MCOOGMHK_01758 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MCOOGMHK_01759 1e-188 ftsE D Cell division ATP-binding protein FtsE
MCOOGMHK_01760 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCOOGMHK_01761 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MCOOGMHK_01762 6e-63
MCOOGMHK_01764 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MCOOGMHK_01765 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCOOGMHK_01766 9.7e-90 3.1.21.3 V DivIVA protein
MCOOGMHK_01767 2.1e-42 yggT S YGGT family
MCOOGMHK_01768 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCOOGMHK_01769 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCOOGMHK_01770 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCOOGMHK_01771 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MCOOGMHK_01772 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
MCOOGMHK_01773 7.5e-158 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MCOOGMHK_01774 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MCOOGMHK_01775 1.3e-84
MCOOGMHK_01776 6.9e-231 O AAA domain (Cdc48 subfamily)
MCOOGMHK_01777 3e-162 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MCOOGMHK_01778 1.2e-61 S Thiamine-binding protein
MCOOGMHK_01779 5.2e-195 K helix_turn _helix lactose operon repressor
MCOOGMHK_01780 5.7e-47 S Protein of unknown function (DUF3052)
MCOOGMHK_01781 1.5e-152 lon T Belongs to the peptidase S16 family
MCOOGMHK_01782 1.1e-286 S Zincin-like metallopeptidase
MCOOGMHK_01783 4.5e-280 uvrD2 3.6.4.12 L DNA helicase
MCOOGMHK_01784 4.6e-245 mphA S Aminoglycoside phosphotransferase
MCOOGMHK_01785 6.1e-32 S Protein of unknown function (DUF3107)
MCOOGMHK_01786 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MCOOGMHK_01787 7.6e-115 S Vitamin K epoxide reductase
MCOOGMHK_01788 2.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MCOOGMHK_01789 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MCOOGMHK_01790 2.3e-168 S Patatin-like phospholipase
MCOOGMHK_01791 4.6e-82 V ABC transporter transmembrane region
MCOOGMHK_01792 2.5e-278 V ABC transporter transmembrane region
MCOOGMHK_01793 0.0 V ABC transporter, ATP-binding protein
MCOOGMHK_01794 1.7e-88 K MarR family
MCOOGMHK_01795 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
MCOOGMHK_01796 1.9e-259 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MCOOGMHK_01797 1.2e-166
MCOOGMHK_01798 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MCOOGMHK_01800 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCOOGMHK_01801 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MCOOGMHK_01802 3.6e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCOOGMHK_01803 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCOOGMHK_01804 9.6e-203 S Endonuclease/Exonuclease/phosphatase family
MCOOGMHK_01807 3.1e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MCOOGMHK_01808 1.3e-254 cdr OP Sulfurtransferase TusA
MCOOGMHK_01809 4.4e-149 moeB 2.7.7.80 H ThiF family
MCOOGMHK_01810 3.5e-132 tmp1 S Domain of unknown function (DUF4391)
MCOOGMHK_01811 9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MCOOGMHK_01812 2.9e-229 aspB E Aminotransferase class-V
MCOOGMHK_01813 4.1e-105 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MCOOGMHK_01814 1.4e-270 S zinc finger
MCOOGMHK_01815 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCOOGMHK_01816 2.1e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCOOGMHK_01817 4.8e-291 O Subtilase family
MCOOGMHK_01818 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MCOOGMHK_01819 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCOOGMHK_01820 2.2e-102 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCOOGMHK_01821 2.8e-45 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCOOGMHK_01822 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCOOGMHK_01823 5.5e-35 L Transposase
MCOOGMHK_01824 6.4e-24 relB L RelB antitoxin
MCOOGMHK_01825 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MCOOGMHK_01826 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MCOOGMHK_01827 3.8e-249 G Major Facilitator Superfamily
MCOOGMHK_01828 3.4e-147 K -acetyltransferase
MCOOGMHK_01829 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MCOOGMHK_01830 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MCOOGMHK_01831 3.4e-269 KLT Protein tyrosine kinase
MCOOGMHK_01832 0.0 S Fibronectin type 3 domain
MCOOGMHK_01833 1.8e-232 S ATPase family associated with various cellular activities (AAA)
MCOOGMHK_01834 5.7e-231 S Protein of unknown function DUF58
MCOOGMHK_01835 0.0 E Transglutaminase-like superfamily
MCOOGMHK_01836 3.7e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
MCOOGMHK_01837 2.8e-68 B Belongs to the OprB family
MCOOGMHK_01838 7.2e-95 T Forkhead associated domain
MCOOGMHK_01839 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCOOGMHK_01840 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCOOGMHK_01841 7.6e-107
MCOOGMHK_01842 2.5e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MCOOGMHK_01843 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MCOOGMHK_01844 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCOOGMHK_01846 2.5e-72
MCOOGMHK_01847 4.7e-252 S UPF0210 protein
MCOOGMHK_01848 4.2e-43 gcvR T Belongs to the UPF0237 family
MCOOGMHK_01849 8.6e-243 EGP Sugar (and other) transporter
MCOOGMHK_01850 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MCOOGMHK_01851 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MCOOGMHK_01852 3.1e-139 glpR K DeoR C terminal sensor domain
MCOOGMHK_01853 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MCOOGMHK_01854 1.1e-217 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MCOOGMHK_01855 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MCOOGMHK_01856 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MCOOGMHK_01857 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MCOOGMHK_01858 4.5e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MCOOGMHK_01859 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MCOOGMHK_01860 5.1e-27 S Uncharacterized conserved protein (DUF2183)
MCOOGMHK_01861 9.2e-201 S Uncharacterized conserved protein (DUF2183)
MCOOGMHK_01862 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MCOOGMHK_01863 0.0 enhA_2 S L,D-transpeptidase catalytic domain
MCOOGMHK_01864 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MCOOGMHK_01865 2.6e-160 mhpC I Alpha/beta hydrolase family
MCOOGMHK_01866 4.8e-119 F Domain of unknown function (DUF4916)
MCOOGMHK_01867 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MCOOGMHK_01868 1.3e-179 S G5
MCOOGMHK_01869 3.2e-212
MCOOGMHK_01870 4.4e-103 K cell envelope-related transcriptional attenuator
MCOOGMHK_01871 9.9e-172 L Transposase and inactivated derivatives IS30 family
MCOOGMHK_01872 3.9e-250 EGP Major facilitator Superfamily
MCOOGMHK_01873 1.4e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MCOOGMHK_01874 2.1e-134 L Protein of unknown function (DUF1524)
MCOOGMHK_01875 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MCOOGMHK_01876 5.9e-203 K helix_turn _helix lactose operon repressor
MCOOGMHK_01877 9.2e-106 G Glycosyl hydrolases family 43
MCOOGMHK_01878 6.1e-172 G Glycosyl hydrolases family 43

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)