ORF_ID e_value Gene_name EC_number CAZy COGs Description
HALMMDKM_00001 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
HALMMDKM_00002 1.5e-172 malR K Transcriptional regulator, LacI family
HALMMDKM_00003 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HALMMDKM_00004 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HALMMDKM_00005 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HALMMDKM_00006 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HALMMDKM_00008 0.0 clpL O associated with various cellular activities
HALMMDKM_00009 7.8e-32
HALMMDKM_00010 6.1e-216 patA 2.6.1.1 E Aminotransferase
HALMMDKM_00011 3.1e-176 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMMDKM_00012 5e-75 osmC O OsmC-like protein
HALMMDKM_00013 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_00014 2.5e-212 bacI V MacB-like periplasmic core domain
HALMMDKM_00015 4.4e-129 V ABC transporter
HALMMDKM_00016 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HALMMDKM_00017 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HALMMDKM_00018 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HALMMDKM_00019 3e-147 E Glyoxalase-like domain
HALMMDKM_00020 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HALMMDKM_00021 2.9e-96 S reductase
HALMMDKM_00023 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HALMMDKM_00024 4.7e-177 ABC-SBP S ABC transporter
HALMMDKM_00025 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HALMMDKM_00026 9.6e-215 htrA 3.4.21.107 O serine protease
HALMMDKM_00027 4.5e-154 vicX 3.1.26.11 S domain protein
HALMMDKM_00028 2.7e-149 yycI S YycH protein
HALMMDKM_00029 2.1e-246 yycH S YycH protein
HALMMDKM_00030 0.0 vicK 2.7.13.3 T Histidine kinase
HALMMDKM_00031 6.8e-130 K response regulator
HALMMDKM_00033 1.3e-293 lmrA 3.6.3.44 V ABC transporter
HALMMDKM_00034 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
HALMMDKM_00036 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HALMMDKM_00037 3.7e-54
HALMMDKM_00038 9.9e-206 yttB EGP Major facilitator Superfamily
HALMMDKM_00039 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HALMMDKM_00040 2e-74 rplI J Binds to the 23S rRNA
HALMMDKM_00041 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HALMMDKM_00042 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HALMMDKM_00043 1.4e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HALMMDKM_00044 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HALMMDKM_00045 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HALMMDKM_00046 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HALMMDKM_00047 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HALMMDKM_00048 1.7e-34 yaaA S S4 domain protein YaaA
HALMMDKM_00049 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HALMMDKM_00050 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HALMMDKM_00051 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HALMMDKM_00052 8.5e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HALMMDKM_00053 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HALMMDKM_00054 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HALMMDKM_00055 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HALMMDKM_00056 9.7e-130 jag S R3H domain protein
HALMMDKM_00057 1.9e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HALMMDKM_00058 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HALMMDKM_00059 0.0 asnB 6.3.5.4 E Asparagine synthase
HALMMDKM_00060 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HALMMDKM_00061 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HALMMDKM_00062 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HALMMDKM_00063 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
HALMMDKM_00064 3.5e-160 S reductase
HALMMDKM_00066 3.6e-288 S amidohydrolase
HALMMDKM_00067 2.5e-164 K Aminotransferase class I and II
HALMMDKM_00068 7.3e-60 K Aminotransferase class I and II
HALMMDKM_00069 1.4e-119 azlC E azaleucine resistance protein AzlC
HALMMDKM_00070 7.1e-50 azlD E Branched-chain amino acid transport
HALMMDKM_00071 5.5e-118 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HALMMDKM_00073 1.2e-91 L PFAM Integrase catalytic region
HALMMDKM_00074 6.4e-113 L PFAM Integrase catalytic region
HALMMDKM_00075 2.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HALMMDKM_00076 1.8e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HALMMDKM_00077 2.2e-72
HALMMDKM_00078 6.2e-76 K Transcriptional regulator, TetR family
HALMMDKM_00079 4.3e-13 K Transcriptional regulator, TetR family
HALMMDKM_00081 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HALMMDKM_00082 3e-86
HALMMDKM_00083 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HALMMDKM_00084 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HALMMDKM_00085 9.3e-261 nox C NADH oxidase
HALMMDKM_00086 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
HALMMDKM_00087 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HALMMDKM_00088 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HALMMDKM_00089 3.8e-167 yvgN C Aldo keto reductase
HALMMDKM_00090 6.6e-136 puuD S peptidase C26
HALMMDKM_00091 5.2e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HALMMDKM_00092 2.5e-209 yfeO P Voltage gated chloride channel
HALMMDKM_00093 5.3e-226 sptS 2.7.13.3 T Histidine kinase
HALMMDKM_00094 3.3e-118 K response regulator
HALMMDKM_00095 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HALMMDKM_00096 1e-71
HALMMDKM_00097 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HALMMDKM_00098 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HALMMDKM_00099 1.1e-256 malT G Major Facilitator
HALMMDKM_00100 4.2e-71 S Uncharacterised protein family (UPF0236)
HALMMDKM_00101 2.1e-60 L PFAM transposase IS200-family protein
HALMMDKM_00102 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HALMMDKM_00103 1.1e-63 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HALMMDKM_00104 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HALMMDKM_00105 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HALMMDKM_00106 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HALMMDKM_00107 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
HALMMDKM_00108 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HALMMDKM_00109 3.4e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HALMMDKM_00110 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HALMMDKM_00111 6e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HALMMDKM_00112 1.3e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HALMMDKM_00113 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HALMMDKM_00114 6.8e-103 cbiQ P Cobalt transport protein
HALMMDKM_00115 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HALMMDKM_00116 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HALMMDKM_00117 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HALMMDKM_00118 4.7e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HALMMDKM_00119 3.3e-176 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HALMMDKM_00120 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HALMMDKM_00121 6.6e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HALMMDKM_00122 1.1e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HALMMDKM_00123 1.4e-128 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HALMMDKM_00124 6.9e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HALMMDKM_00125 2.7e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HALMMDKM_00126 1.7e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HALMMDKM_00127 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HALMMDKM_00128 1.9e-146 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HALMMDKM_00129 3e-206 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HALMMDKM_00130 4.7e-170 cobD 4.1.1.81 E Aminotransferase class I and II
HALMMDKM_00131 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HALMMDKM_00132 2.3e-116 XK27_04590 S NADPH-dependent FMN reductase
HALMMDKM_00133 2.2e-73 fld C Flavodoxin
HALMMDKM_00134 1e-67 eutP E Ethanolamine utilisation - propanediol utilisation
HALMMDKM_00135 5.9e-68 P Cadmium resistance transporter
HALMMDKM_00136 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
HALMMDKM_00137 4.4e-117 3.1.3.48 T Pfam:Y_phosphatase3C
HALMMDKM_00138 3e-54 pduU E BMC
HALMMDKM_00139 3.8e-218 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HALMMDKM_00140 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
HALMMDKM_00141 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HALMMDKM_00142 2e-77 pduO S Haem-degrading
HALMMDKM_00143 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HALMMDKM_00144 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HALMMDKM_00145 1.3e-79 S Putative propanediol utilisation
HALMMDKM_00146 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HALMMDKM_00147 7.8e-40 pduA_4 CQ BMC
HALMMDKM_00148 3.6e-57 pduK CQ BMC
HALMMDKM_00149 8.1e-45 pduH S Dehydratase medium subunit
HALMMDKM_00150 3.1e-307 pduG D Diol dehydratase reactivase ATPase-like domain
HALMMDKM_00151 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
HALMMDKM_00152 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HALMMDKM_00153 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HALMMDKM_00154 2.7e-134 pduB E BMC
HALMMDKM_00155 1.6e-37 pduA_4 CQ BMC
HALMMDKM_00156 8.3e-159 K helix_turn_helix, arabinose operon control protein
HALMMDKM_00157 3.6e-138 eutJ E Hsp70 protein
HALMMDKM_00158 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HALMMDKM_00159 3.2e-95
HALMMDKM_00160 6.4e-127 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HALMMDKM_00161 5.9e-152 S AI-2E family transporter
HALMMDKM_00162 2.2e-131 XK27_07210 6.1.1.6 S B3 4 domain
HALMMDKM_00163 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HALMMDKM_00164 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HALMMDKM_00165 4.8e-88 GM epimerase
HALMMDKM_00166 1.3e-154 ypdB V (ABC) transporter
HALMMDKM_00167 5.8e-239 yhdP S Transporter associated domain
HALMMDKM_00168 5.4e-83 nrdI F Belongs to the NrdI family
HALMMDKM_00169 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
HALMMDKM_00170 7.2e-193 yeaN P Transporter, major facilitator family protein
HALMMDKM_00171 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HALMMDKM_00172 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HALMMDKM_00173 8.2e-35
HALMMDKM_00174 0.0 lacS G Transporter
HALMMDKM_00175 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
HALMMDKM_00176 1.5e-80 uspA T universal stress protein
HALMMDKM_00177 1.5e-80 K AsnC family
HALMMDKM_00178 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HALMMDKM_00179 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HALMMDKM_00180 2e-180 galR K Transcriptional regulator
HALMMDKM_00181 2.2e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HALMMDKM_00182 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HALMMDKM_00183 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HALMMDKM_00184 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HALMMDKM_00185 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
HALMMDKM_00186 9.1e-36
HALMMDKM_00187 5.9e-52
HALMMDKM_00188 2.5e-203
HALMMDKM_00189 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HALMMDKM_00190 8.9e-136 pnuC H nicotinamide mononucleotide transporter
HALMMDKM_00191 3e-156 ytbE 1.1.1.346 S Aldo keto reductase
HALMMDKM_00192 1.7e-179 T PhoQ Sensor
HALMMDKM_00193 4.9e-134 macB2 V ABC transporter, ATP-binding protein
HALMMDKM_00194 0.0 ysaB V FtsX-like permease family
HALMMDKM_00195 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HALMMDKM_00196 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HALMMDKM_00197 6.1e-54 K helix_turn_helix, mercury resistance
HALMMDKM_00198 2.7e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HALMMDKM_00199 1.6e-197 EGP Major facilitator Superfamily
HALMMDKM_00200 2.1e-88 ymdB S Macro domain protein
HALMMDKM_00201 8.4e-111 K Helix-turn-helix domain
HALMMDKM_00202 0.0 pepO 3.4.24.71 O Peptidase family M13
HALMMDKM_00203 5.1e-47
HALMMDKM_00204 2.1e-241 S Putative metallopeptidase domain
HALMMDKM_00205 3e-204 3.1.3.1 S associated with various cellular activities
HALMMDKM_00206 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HALMMDKM_00207 1.6e-64 yeaO S Protein of unknown function, DUF488
HALMMDKM_00209 5.4e-116 yrkL S Flavodoxin-like fold
HALMMDKM_00210 9.5e-55
HALMMDKM_00211 2e-15 S Domain of unknown function (DUF4767)
HALMMDKM_00212 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HALMMDKM_00213 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HALMMDKM_00214 6.9e-49
HALMMDKM_00216 1.7e-204 nrnB S DHHA1 domain
HALMMDKM_00217 3.3e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HALMMDKM_00218 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HALMMDKM_00219 2e-106 NU mannosyl-glycoprotein
HALMMDKM_00220 2.3e-142 S Putative ABC-transporter type IV
HALMMDKM_00221 2.3e-271 S ABC transporter, ATP-binding protein
HALMMDKM_00222 8.2e-48
HALMMDKM_00223 5.2e-189 L PFAM Integrase catalytic region
HALMMDKM_00224 6.1e-37 L Transposase
HALMMDKM_00225 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HALMMDKM_00226 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HALMMDKM_00227 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HALMMDKM_00228 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HALMMDKM_00229 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HALMMDKM_00230 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HALMMDKM_00231 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HALMMDKM_00232 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HALMMDKM_00233 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HALMMDKM_00234 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
HALMMDKM_00235 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HALMMDKM_00236 6.8e-121 radC L DNA repair protein
HALMMDKM_00237 1.7e-179 mreB D cell shape determining protein MreB
HALMMDKM_00238 2.2e-151 mreC M Involved in formation and maintenance of cell shape
HALMMDKM_00239 1.2e-91 mreD M rod shape-determining protein MreD
HALMMDKM_00240 3.2e-102 glnP P ABC transporter permease
HALMMDKM_00241 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_00242 2.6e-160 aatB ET ABC transporter substrate-binding protein
HALMMDKM_00243 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HALMMDKM_00244 3.2e-250 ymfH S Peptidase M16
HALMMDKM_00245 7.4e-141 ymfM S Helix-turn-helix domain
HALMMDKM_00246 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HALMMDKM_00247 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
HALMMDKM_00248 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HALMMDKM_00249 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HALMMDKM_00250 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HALMMDKM_00251 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HALMMDKM_00252 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HALMMDKM_00253 2.2e-202 ykiI
HALMMDKM_00254 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMMDKM_00255 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMMDKM_00256 1e-110 K Bacterial regulatory proteins, tetR family
HALMMDKM_00257 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HALMMDKM_00258 3.4e-77 ctsR K Belongs to the CtsR family
HALMMDKM_00259 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HALMMDKM_00260 3.9e-16 S Hydrolases of the alpha beta superfamily
HALMMDKM_00261 5.3e-130 S Hydrolases of the alpha beta superfamily
HALMMDKM_00267 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HALMMDKM_00268 1.5e-275 lysP E amino acid
HALMMDKM_00269 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HALMMDKM_00270 2.7e-120 lssY 3.6.1.27 I phosphatase
HALMMDKM_00271 6.7e-81 S Threonine/Serine exporter, ThrE
HALMMDKM_00272 3.6e-129 thrE S Putative threonine/serine exporter
HALMMDKM_00273 3.5e-31 cspC K Cold shock protein
HALMMDKM_00274 1.1e-124 sirR K iron dependent repressor
HALMMDKM_00275 1.9e-164 czcD P cation diffusion facilitator family transporter
HALMMDKM_00276 6.5e-117 S membrane
HALMMDKM_00277 7.6e-110 S VIT family
HALMMDKM_00278 5.5e-83 usp1 T Belongs to the universal stress protein A family
HALMMDKM_00279 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_00280 4.8e-151 glnH ET ABC transporter
HALMMDKM_00281 4.2e-110 gluC P ABC transporter permease
HALMMDKM_00282 1.4e-108 glnP P ABC transporter permease
HALMMDKM_00283 1.1e-217 S CAAX protease self-immunity
HALMMDKM_00284 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HALMMDKM_00285 2.5e-53
HALMMDKM_00286 4.9e-73 merR K MerR HTH family regulatory protein
HALMMDKM_00287 2.7e-269 lmrB EGP Major facilitator Superfamily
HALMMDKM_00288 9.5e-119 S Domain of unknown function (DUF4811)
HALMMDKM_00289 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HALMMDKM_00291 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HALMMDKM_00292 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HALMMDKM_00293 3.4e-188 I Alpha beta
HALMMDKM_00294 8.5e-282 emrY EGP Major facilitator Superfamily
HALMMDKM_00295 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HALMMDKM_00296 2e-250 yjjP S Putative threonine/serine exporter
HALMMDKM_00297 1e-159 mleR K LysR family
HALMMDKM_00298 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
HALMMDKM_00299 1.8e-267 frdC 1.3.5.4 C FAD binding domain
HALMMDKM_00300 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HALMMDKM_00301 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HALMMDKM_00302 1.9e-161 mleR K LysR family
HALMMDKM_00303 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HALMMDKM_00304 4.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HALMMDKM_00305 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
HALMMDKM_00306 1.6e-168 L transposase, IS605 OrfB family
HALMMDKM_00307 2.7e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
HALMMDKM_00308 5.6e-25
HALMMDKM_00309 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HALMMDKM_00310 3e-75
HALMMDKM_00311 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HALMMDKM_00312 1.1e-64 L PFAM Integrase catalytic region
HALMMDKM_00313 1.5e-118 L PFAM Integrase catalytic region
HALMMDKM_00314 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HALMMDKM_00315 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HALMMDKM_00316 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HALMMDKM_00317 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HALMMDKM_00318 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
HALMMDKM_00319 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HALMMDKM_00320 5.9e-58 yabA L Involved in initiation control of chromosome replication
HALMMDKM_00321 2.8e-185 holB 2.7.7.7 L DNA polymerase III
HALMMDKM_00322 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HALMMDKM_00323 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HALMMDKM_00324 9.7e-39 S Protein of unknown function (DUF2508)
HALMMDKM_00325 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HALMMDKM_00326 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HALMMDKM_00327 8.1e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HALMMDKM_00328 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HALMMDKM_00329 3.4e-35 nrdH O Glutaredoxin
HALMMDKM_00330 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HALMMDKM_00331 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HALMMDKM_00332 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HALMMDKM_00333 6.4e-126 S Putative adhesin
HALMMDKM_00334 3.5e-82 XK27_06920 S Protein of unknown function (DUF1700)
HALMMDKM_00335 4e-56 K transcriptional regulator PadR family
HALMMDKM_00336 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HALMMDKM_00338 1.5e-48
HALMMDKM_00339 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HALMMDKM_00340 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HALMMDKM_00341 4.3e-192 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HALMMDKM_00342 2.8e-246 M Glycosyl transferase family group 2
HALMMDKM_00344 2.3e-84
HALMMDKM_00345 7.1e-248 yifK E Amino acid permease
HALMMDKM_00346 2.6e-291 clcA P chloride
HALMMDKM_00347 1.8e-34 secG U Preprotein translocase
HALMMDKM_00348 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
HALMMDKM_00349 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HALMMDKM_00350 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HALMMDKM_00351 6.3e-105 yxjI
HALMMDKM_00352 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HALMMDKM_00353 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HALMMDKM_00354 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HALMMDKM_00355 2.8e-85 K Acetyltransferase (GNAT) domain
HALMMDKM_00356 4.4e-76 S PAS domain
HALMMDKM_00357 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HALMMDKM_00358 3.6e-168 murB 1.3.1.98 M Cell wall formation
HALMMDKM_00359 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HALMMDKM_00360 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HALMMDKM_00361 6.1e-244 fucP G Major Facilitator Superfamily
HALMMDKM_00362 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HALMMDKM_00363 2e-126 ybbR S YbbR-like protein
HALMMDKM_00364 2.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HALMMDKM_00365 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HALMMDKM_00366 8.7e-53
HALMMDKM_00367 0.0 oatA I Acyltransferase
HALMMDKM_00368 2.3e-81 K Transcriptional regulator
HALMMDKM_00369 2e-149 XK27_02985 S Cof-like hydrolase
HALMMDKM_00370 2.8e-79 lytE M Lysin motif
HALMMDKM_00372 1.5e-132 K response regulator
HALMMDKM_00373 6.8e-273 yclK 2.7.13.3 T Histidine kinase
HALMMDKM_00374 2.6e-155 glcU U sugar transport
HALMMDKM_00375 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
HALMMDKM_00376 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HALMMDKM_00377 1.3e-28
HALMMDKM_00378 5.4e-31 xylR GK ROK family
HALMMDKM_00379 5.6e-65 S NADPH-dependent FMN reductase
HALMMDKM_00380 8.7e-09 S NADPH-dependent FMN reductase
HALMMDKM_00381 1.5e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HALMMDKM_00382 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HALMMDKM_00383 7.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HALMMDKM_00384 1.2e-81 Q Methyltransferase
HALMMDKM_00385 1.4e-116 ktrA P domain protein
HALMMDKM_00386 1.7e-238 ktrB P Potassium uptake protein
HALMMDKM_00387 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HALMMDKM_00388 4.6e-58 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HALMMDKM_00389 8.6e-72 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HALMMDKM_00390 2e-216 G Glycosyl hydrolases family 8
HALMMDKM_00391 1.9e-242 ydaM M Glycosyl transferase
HALMMDKM_00392 1.1e-142
HALMMDKM_00393 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
HALMMDKM_00394 2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HALMMDKM_00395 5.5e-153 pstA P Phosphate transport system permease protein PstA
HALMMDKM_00396 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HALMMDKM_00397 1.2e-157 pstS P Phosphate
HALMMDKM_00398 1.7e-133 K Transcriptional regulatory protein, C-terminal domain protein
HALMMDKM_00399 5.3e-77 L PFAM Integrase catalytic region
HALMMDKM_00400 4.1e-37 S Uncharacterised protein family (UPF0236)
HALMMDKM_00401 1.6e-52 azlD S branched-chain amino acid
HALMMDKM_00402 3.7e-136 azlC E AzlC protein
HALMMDKM_00403 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
HALMMDKM_00404 1.2e-123 K response regulator
HALMMDKM_00405 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HALMMDKM_00406 9.5e-172 deoR K sugar-binding domain protein
HALMMDKM_00407 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HALMMDKM_00408 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HALMMDKM_00409 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HALMMDKM_00410 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HALMMDKM_00411 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HALMMDKM_00412 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HALMMDKM_00413 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HALMMDKM_00414 1.7e-154 spo0J K Belongs to the ParB family
HALMMDKM_00415 3.9e-139 soj D Sporulation initiation inhibitor
HALMMDKM_00416 4.3e-151 noc K Belongs to the ParB family
HALMMDKM_00417 6.6e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HALMMDKM_00418 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HALMMDKM_00419 5.6e-169 rihC 3.2.2.1 F Nucleoside
HALMMDKM_00420 2.3e-218 nupG F Nucleoside transporter
HALMMDKM_00421 3.2e-221 cycA E Amino acid permease
HALMMDKM_00423 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_00424 1.2e-264 glnP P ABC transporter
HALMMDKM_00425 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HALMMDKM_00426 4.3e-109 L hmm pf00665
HALMMDKM_00427 5.5e-110 dedA S SNARE-like domain protein
HALMMDKM_00428 2.4e-105 S Protein of unknown function (DUF1461)
HALMMDKM_00429 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HALMMDKM_00430 1.3e-93 yutD S Protein of unknown function (DUF1027)
HALMMDKM_00431 2.2e-113 S Calcineurin-like phosphoesterase
HALMMDKM_00432 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HALMMDKM_00433 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HALMMDKM_00435 6.3e-70
HALMMDKM_00436 2.7e-40
HALMMDKM_00437 8.3e-78 NU general secretion pathway protein
HALMMDKM_00438 7.1e-47 comGC U competence protein ComGC
HALMMDKM_00439 9.5e-181 comGB NU type II secretion system
HALMMDKM_00440 2.6e-180 comGA NU Type II IV secretion system protein
HALMMDKM_00441 3.5e-132 yebC K Transcriptional regulatory protein
HALMMDKM_00442 1.9e-134
HALMMDKM_00443 7.1e-181 ccpA K catabolite control protein A
HALMMDKM_00444 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HALMMDKM_00445 3.5e-26
HALMMDKM_00446 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HALMMDKM_00447 3.4e-147 ykuT M mechanosensitive ion channel
HALMMDKM_00448 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HALMMDKM_00449 3.6e-76 ykuL S (CBS) domain
HALMMDKM_00450 4.4e-94 S Phosphoesterase
HALMMDKM_00451 3.8e-102 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HALMMDKM_00452 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HALMMDKM_00453 1.3e-96 yslB S Protein of unknown function (DUF2507)
HALMMDKM_00454 6.1e-54 trxA O Belongs to the thioredoxin family
HALMMDKM_00455 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HALMMDKM_00456 1e-85 cvpA S Colicin V production protein
HALMMDKM_00457 6.1e-48 yrzB S Belongs to the UPF0473 family
HALMMDKM_00458 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HALMMDKM_00459 4.1e-43 yrzL S Belongs to the UPF0297 family
HALMMDKM_00460 1.1e-64 L PFAM Integrase catalytic region
HALMMDKM_00461 2.7e-120 S Uncharacterised protein family (UPF0236)
HALMMDKM_00462 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HALMMDKM_00463 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HALMMDKM_00464 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HALMMDKM_00465 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HALMMDKM_00466 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HALMMDKM_00467 2.9e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HALMMDKM_00468 2.8e-31 yajC U Preprotein translocase
HALMMDKM_00469 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HALMMDKM_00470 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HALMMDKM_00471 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HALMMDKM_00472 1.1e-77 L PFAM Integrase catalytic region
HALMMDKM_00473 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HALMMDKM_00474 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HALMMDKM_00475 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HALMMDKM_00476 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HALMMDKM_00478 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HALMMDKM_00479 2e-239 glpT G Major Facilitator Superfamily
HALMMDKM_00480 8.8e-15
HALMMDKM_00482 4e-170 whiA K May be required for sporulation
HALMMDKM_00483 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HALMMDKM_00484 1.1e-161 rapZ S Displays ATPase and GTPase activities
HALMMDKM_00485 5.4e-245 steT E amino acid
HALMMDKM_00486 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HALMMDKM_00487 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HALMMDKM_00488 1.5e-13
HALMMDKM_00489 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HALMMDKM_00490 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HALMMDKM_00491 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HALMMDKM_00492 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
HALMMDKM_00493 8.4e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HALMMDKM_00494 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HALMMDKM_00495 3.5e-163 lutA C Cysteine-rich domain
HALMMDKM_00496 7.5e-288 lutB C 4Fe-4S dicluster domain
HALMMDKM_00497 3.9e-136 yrjD S LUD domain
HALMMDKM_00498 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HALMMDKM_00499 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HALMMDKM_00500 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HALMMDKM_00501 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HALMMDKM_00502 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HALMMDKM_00503 3.5e-31 KT PspC domain protein
HALMMDKM_00504 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HALMMDKM_00505 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HALMMDKM_00506 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HALMMDKM_00507 1.3e-114 comFC S Competence protein
HALMMDKM_00508 1.4e-256 comFA L Helicase C-terminal domain protein
HALMMDKM_00509 2.9e-111 yvyE 3.4.13.9 S YigZ family
HALMMDKM_00510 5.4e-235 EGP Major facilitator Superfamily
HALMMDKM_00511 7.4e-68 rmaI K Transcriptional regulator
HALMMDKM_00512 9.2e-40
HALMMDKM_00513 0.0 ydaO E amino acid
HALMMDKM_00514 4.3e-305 ybeC E amino acid
HALMMDKM_00515 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
HALMMDKM_00516 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HALMMDKM_00517 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HALMMDKM_00519 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HALMMDKM_00520 0.0 uup S ABC transporter, ATP-binding protein
HALMMDKM_00521 4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HALMMDKM_00522 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
HALMMDKM_00523 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HALMMDKM_00524 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HALMMDKM_00525 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HALMMDKM_00526 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HALMMDKM_00527 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HALMMDKM_00528 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HALMMDKM_00529 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HALMMDKM_00530 4e-92 L PFAM Integrase catalytic region
HALMMDKM_00531 1.1e-77 L PFAM Integrase catalytic region
HALMMDKM_00532 4.8e-132 ponA V Beta-lactamase enzyme family
HALMMDKM_00533 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HALMMDKM_00534 5.3e-215 uhpT EGP Major facilitator Superfamily
HALMMDKM_00535 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
HALMMDKM_00536 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
HALMMDKM_00537 9.6e-180 yfeX P Peroxidase
HALMMDKM_00538 4.1e-169 lsa S ABC transporter
HALMMDKM_00539 7.2e-135 I alpha/beta hydrolase fold
HALMMDKM_00540 4.7e-180 MA20_14895 S Conserved hypothetical protein 698
HALMMDKM_00541 1.9e-219 G Belongs to the glycosyl hydrolase family 6
HALMMDKM_00542 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_00543 4.1e-160
HALMMDKM_00544 3.1e-95 2.3.1.128 K acetyltransferase
HALMMDKM_00545 1.2e-75 manA 5.3.1.8 G mannose-6-phosphate isomerase
HALMMDKM_00546 1.1e-156 K LysR substrate binding domain
HALMMDKM_00547 3.4e-200 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HALMMDKM_00548 1.4e-59 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HALMMDKM_00550 2e-162
HALMMDKM_00551 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HALMMDKM_00552 5.8e-184 S Phosphotransferase system, EIIC
HALMMDKM_00553 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HALMMDKM_00554 1.7e-84 F NUDIX domain
HALMMDKM_00555 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HALMMDKM_00556 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HALMMDKM_00557 5.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HALMMDKM_00558 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HALMMDKM_00559 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HALMMDKM_00560 2.4e-161 dprA LU DNA protecting protein DprA
HALMMDKM_00561 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HALMMDKM_00562 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HALMMDKM_00563 4.4e-35 yozE S Belongs to the UPF0346 family
HALMMDKM_00564 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HALMMDKM_00565 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HALMMDKM_00566 1.7e-151 DegV S EDD domain protein, DegV family
HALMMDKM_00567 9e-113 hlyIII S protein, hemolysin III
HALMMDKM_00568 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HALMMDKM_00569 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HALMMDKM_00570 0.0 yfmR S ABC transporter, ATP-binding protein
HALMMDKM_00571 2.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HALMMDKM_00572 1.5e-236 S Tetratricopeptide repeat protein
HALMMDKM_00573 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HALMMDKM_00574 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HALMMDKM_00575 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HALMMDKM_00576 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HALMMDKM_00577 8.5e-14 M Lysin motif
HALMMDKM_00578 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HALMMDKM_00579 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HALMMDKM_00580 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HALMMDKM_00581 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HALMMDKM_00582 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HALMMDKM_00583 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HALMMDKM_00584 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HALMMDKM_00585 1.2e-163 xerD D recombinase XerD
HALMMDKM_00586 2.3e-167 cvfB S S1 domain
HALMMDKM_00587 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HALMMDKM_00588 0.0 dnaE 2.7.7.7 L DNA polymerase
HALMMDKM_00589 3.1e-30 S Protein of unknown function (DUF2929)
HALMMDKM_00590 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HALMMDKM_00591 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HALMMDKM_00592 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HALMMDKM_00593 1.2e-219 patA 2.6.1.1 E Aminotransferase
HALMMDKM_00594 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HALMMDKM_00595 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HALMMDKM_00596 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HALMMDKM_00597 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HALMMDKM_00598 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HALMMDKM_00599 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HALMMDKM_00600 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HALMMDKM_00601 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HALMMDKM_00602 5.8e-183 phoH T phosphate starvation-inducible protein PhoH
HALMMDKM_00603 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HALMMDKM_00604 9.6e-90 bioY S BioY family
HALMMDKM_00605 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
HALMMDKM_00606 8.6e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HALMMDKM_00607 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HALMMDKM_00608 1.5e-76 L PFAM Integrase catalytic region
HALMMDKM_00609 2.2e-75 L hmm pf00665
HALMMDKM_00610 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HALMMDKM_00611 3e-34
HALMMDKM_00612 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HALMMDKM_00613 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HALMMDKM_00614 2.6e-86 ygfC K transcriptional regulator (TetR family)
HALMMDKM_00615 2.1e-183 hrtB V ABC transporter permease
HALMMDKM_00616 6.7e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HALMMDKM_00617 0.0 yhcA V ABC transporter, ATP-binding protein
HALMMDKM_00618 4.6e-38
HALMMDKM_00619 2.3e-48 czrA K Transcriptional regulator, ArsR family
HALMMDKM_00620 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HALMMDKM_00621 1e-90 S Uncharacterised protein family (UPF0236)
HALMMDKM_00622 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HALMMDKM_00624 7.2e-101
HALMMDKM_00625 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HALMMDKM_00626 5.5e-126 S Alpha beta hydrolase
HALMMDKM_00627 1.7e-207 gldA 1.1.1.6 C dehydrogenase
HALMMDKM_00628 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HALMMDKM_00629 1.3e-41
HALMMDKM_00630 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HALMMDKM_00631 1.1e-27 S C4-dicarboxylate anaerobic carrier
HALMMDKM_00632 1.2e-239 S C4-dicarboxylate anaerobic carrier
HALMMDKM_00633 1.8e-251 nhaC C Na H antiporter NhaC
HALMMDKM_00634 6.2e-241 pbuX F xanthine permease
HALMMDKM_00635 1.4e-283 pipD E Dipeptidase
HALMMDKM_00636 1.6e-305 L Transposase
HALMMDKM_00637 2.2e-168 corA P CorA-like Mg2+ transporter protein
HALMMDKM_00638 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HALMMDKM_00639 2.3e-131 terC P membrane
HALMMDKM_00640 2.1e-54 trxA O Belongs to the thioredoxin family
HALMMDKM_00641 3.5e-236 mepA V MATE efflux family protein
HALMMDKM_00642 3.2e-55 M Leucine-rich repeat (LRR) protein
HALMMDKM_00643 6.8e-56 K Transcriptional regulator, ArsR family
HALMMDKM_00644 5.9e-92 P Cadmium resistance transporter
HALMMDKM_00645 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HALMMDKM_00646 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HALMMDKM_00647 2.2e-182 ABC-SBP S ABC transporter
HALMMDKM_00648 1.3e-73 M PFAM NLP P60 protein
HALMMDKM_00649 7.4e-89 L Transposase
HALMMDKM_00650 1.6e-219 norA EGP Major facilitator Superfamily
HALMMDKM_00651 5.8e-40 1.3.5.4 S FMN binding
HALMMDKM_00652 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HALMMDKM_00653 1e-265 yfnA E amino acid
HALMMDKM_00654 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HALMMDKM_00656 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HALMMDKM_00657 0.0 helD 3.6.4.12 L DNA helicase
HALMMDKM_00658 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HALMMDKM_00659 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HALMMDKM_00660 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HALMMDKM_00661 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HALMMDKM_00662 4.7e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HALMMDKM_00663 1.6e-177
HALMMDKM_00664 2e-129 cobB K SIR2 family
HALMMDKM_00666 3.6e-162 yunF F Protein of unknown function DUF72
HALMMDKM_00667 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HALMMDKM_00668 1.9e-155 tatD L hydrolase, TatD family
HALMMDKM_00669 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HALMMDKM_00670 6.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HALMMDKM_00671 6.8e-37 veg S Biofilm formation stimulator VEG
HALMMDKM_00672 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HALMMDKM_00673 3.1e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HALMMDKM_00674 1.4e-121 fhuC P ABC transporter
HALMMDKM_00675 1.4e-118 znuB U ABC 3 transport family
HALMMDKM_00676 2.6e-149 purR 2.4.2.7 F pur operon repressor
HALMMDKM_00677 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HALMMDKM_00678 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HALMMDKM_00679 2.1e-49
HALMMDKM_00680 2.5e-147 yxeH S hydrolase
HALMMDKM_00681 1.5e-269 ywfO S HD domain protein
HALMMDKM_00682 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HALMMDKM_00683 3e-66 ywiB S Domain of unknown function (DUF1934)
HALMMDKM_00684 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HALMMDKM_00685 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HALMMDKM_00686 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HALMMDKM_00687 4.6e-41 rpmE2 J Ribosomal protein L31
HALMMDKM_00688 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HALMMDKM_00689 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HALMMDKM_00690 5.1e-125 srtA 3.4.22.70 M sortase family
HALMMDKM_00691 4.3e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HALMMDKM_00692 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HALMMDKM_00693 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HALMMDKM_00694 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HALMMDKM_00695 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HALMMDKM_00696 7e-93 lemA S LemA family
HALMMDKM_00697 2.6e-158 htpX O Belongs to the peptidase M48B family
HALMMDKM_00698 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HALMMDKM_00699 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HALMMDKM_00700 1.5e-105 L PFAM Integrase catalytic region
HALMMDKM_00701 5.9e-16 sprD D Domain of Unknown Function (DUF1542)
HALMMDKM_00702 1.8e-107 L hmm pf00665
HALMMDKM_00703 9.4e-17 UW LPXTG-motif cell wall anchor domain protein
HALMMDKM_00704 6.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HALMMDKM_00705 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HALMMDKM_00706 4.6e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HALMMDKM_00707 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HALMMDKM_00708 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HALMMDKM_00709 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HALMMDKM_00710 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HALMMDKM_00711 5.5e-217 patA 2.6.1.1 E Aminotransferase
HALMMDKM_00712 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HALMMDKM_00713 8.5e-84 KT Putative sugar diacid recognition
HALMMDKM_00714 1.7e-219 EG GntP family permease
HALMMDKM_00715 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HALMMDKM_00716 7.7e-58
HALMMDKM_00718 1.2e-133 mltD CBM50 M NlpC P60 family protein
HALMMDKM_00719 5.7e-29
HALMMDKM_00720 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HALMMDKM_00721 9.8e-32 ykzG S Belongs to the UPF0356 family
HALMMDKM_00722 2.4e-78
HALMMDKM_00723 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HALMMDKM_00724 6.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HALMMDKM_00725 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HALMMDKM_00726 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HALMMDKM_00727 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
HALMMDKM_00728 1.4e-47 yktA S Belongs to the UPF0223 family
HALMMDKM_00729 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HALMMDKM_00730 0.0 typA T GTP-binding protein TypA
HALMMDKM_00731 3.5e-222 ftsW D Belongs to the SEDS family
HALMMDKM_00732 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HALMMDKM_00733 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HALMMDKM_00734 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HALMMDKM_00735 6.7e-198 ylbL T Belongs to the peptidase S16 family
HALMMDKM_00736 2.6e-80 comEA L Competence protein ComEA
HALMMDKM_00737 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
HALMMDKM_00738 0.0 comEC S Competence protein ComEC
HALMMDKM_00739 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HALMMDKM_00740 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HALMMDKM_00741 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HALMMDKM_00742 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HALMMDKM_00743 3.5e-163 S Tetratricopeptide repeat
HALMMDKM_00744 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HALMMDKM_00745 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HALMMDKM_00746 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HALMMDKM_00747 4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HALMMDKM_00748 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HALMMDKM_00749 1.3e-08
HALMMDKM_00750 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HALMMDKM_00751 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HALMMDKM_00752 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HALMMDKM_00753 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HALMMDKM_00754 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HALMMDKM_00755 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HALMMDKM_00756 2.1e-87
HALMMDKM_00758 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HALMMDKM_00759 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HALMMDKM_00760 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HALMMDKM_00761 1.3e-35 ynzC S UPF0291 protein
HALMMDKM_00762 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HALMMDKM_00763 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HALMMDKM_00764 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
HALMMDKM_00765 5.4e-49 yazA L GIY-YIG catalytic domain protein
HALMMDKM_00766 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMMDKM_00767 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HALMMDKM_00768 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HALMMDKM_00769 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HALMMDKM_00770 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HALMMDKM_00771 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HALMMDKM_00772 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HALMMDKM_00773 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HALMMDKM_00774 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HALMMDKM_00775 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HALMMDKM_00776 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HALMMDKM_00777 1e-215 nusA K Participates in both transcription termination and antitermination
HALMMDKM_00778 1e-44 ylxR K Protein of unknown function (DUF448)
HALMMDKM_00779 4.5e-49 ylxQ J ribosomal protein
HALMMDKM_00780 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HALMMDKM_00781 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HALMMDKM_00782 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HALMMDKM_00783 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HALMMDKM_00784 3.9e-50 L Bacterial dnaA protein
HALMMDKM_00785 2.4e-74 L transposase, IS605 OrfB family
HALMMDKM_00786 4.8e-07 cnrT EG EamA-like transporter family
HALMMDKM_00787 9.8e-51 S Domain of unknown function (DUF4430)
HALMMDKM_00788 5.9e-73 S ECF transporter, substrate-specific component
HALMMDKM_00789 2.9e-19 S PFAM Archaeal ATPase
HALMMDKM_00790 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMMDKM_00791 1.7e-17 K Winged helix DNA-binding domain
HALMMDKM_00792 1.7e-286 lmrA V ABC transporter, ATP-binding protein
HALMMDKM_00793 0.0 yfiC V ABC transporter
HALMMDKM_00794 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HALMMDKM_00795 2.6e-269 pipD E Dipeptidase
HALMMDKM_00796 1.3e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HALMMDKM_00797 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
HALMMDKM_00798 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HALMMDKM_00799 2.7e-244 yagE E amino acid
HALMMDKM_00800 4.5e-140 aroD S Serine hydrolase (FSH1)
HALMMDKM_00801 6.9e-240 brnQ U Component of the transport system for branched-chain amino acids
HALMMDKM_00802 5.2e-167 GK ROK family
HALMMDKM_00803 0.0 tetP J elongation factor G
HALMMDKM_00804 5.1e-81 uspA T universal stress protein
HALMMDKM_00805 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HALMMDKM_00806 7.1e-63
HALMMDKM_00807 5.2e-14
HALMMDKM_00808 1.4e-212 EGP Major facilitator Superfamily
HALMMDKM_00809 1.3e-257 G PTS system Galactitol-specific IIC component
HALMMDKM_00810 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
HALMMDKM_00811 1.1e-161
HALMMDKM_00812 1e-72 K Transcriptional regulator
HALMMDKM_00813 1.8e-189 D Alpha beta
HALMMDKM_00814 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HALMMDKM_00815 0.0 yjcE P Sodium proton antiporter
HALMMDKM_00816 1.6e-52 yvlA
HALMMDKM_00817 1.8e-113 P Cobalt transport protein
HALMMDKM_00818 1e-246 cbiO1 S ABC transporter, ATP-binding protein
HALMMDKM_00819 3e-96 S ABC-type cobalt transport system, permease component
HALMMDKM_00820 3.3e-133 S membrane transporter protein
HALMMDKM_00821 2.5e-138 IQ KR domain
HALMMDKM_00822 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HALMMDKM_00823 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HALMMDKM_00824 6.7e-150 L hmm pf00665
HALMMDKM_00825 2.5e-127 L Helix-turn-helix domain
HALMMDKM_00826 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HALMMDKM_00827 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HALMMDKM_00828 5.3e-77 L PFAM Integrase catalytic region
HALMMDKM_00829 1.1e-114 M domain protein
HALMMDKM_00830 3.1e-44 M domain protein
HALMMDKM_00831 1.9e-32
HALMMDKM_00832 3.9e-187 ampC V Beta-lactamase
HALMMDKM_00833 4.1e-239 arcA 3.5.3.6 E Arginine
HALMMDKM_00834 4.7e-79 argR K Regulates arginine biosynthesis genes
HALMMDKM_00835 2e-261 E Arginine ornithine antiporter
HALMMDKM_00836 2.7e-223 arcD U Amino acid permease
HALMMDKM_00837 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HALMMDKM_00838 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HALMMDKM_00839 6e-108 tdk 2.7.1.21 F thymidine kinase
HALMMDKM_00840 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HALMMDKM_00841 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HALMMDKM_00842 3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HALMMDKM_00843 8.5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HALMMDKM_00844 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HALMMDKM_00845 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HALMMDKM_00846 2.6e-56 ftsL D Cell division protein FtsL
HALMMDKM_00847 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HALMMDKM_00848 3.1e-77 mraZ K Belongs to the MraZ family
HALMMDKM_00849 7.3e-56
HALMMDKM_00850 1.2e-10 S Protein of unknown function (DUF4044)
HALMMDKM_00851 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HALMMDKM_00852 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HALMMDKM_00853 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
HALMMDKM_00854 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HALMMDKM_00856 1.1e-71 L Transposase IS66 family
HALMMDKM_00857 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HALMMDKM_00858 9.7e-173
HALMMDKM_00859 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HALMMDKM_00860 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HALMMDKM_00861 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HALMMDKM_00862 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HALMMDKM_00863 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HALMMDKM_00864 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HALMMDKM_00865 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMMDKM_00866 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMMDKM_00867 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HALMMDKM_00868 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HALMMDKM_00869 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HALMMDKM_00870 4e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HALMMDKM_00871 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HALMMDKM_00872 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HALMMDKM_00873 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HALMMDKM_00874 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HALMMDKM_00875 4.9e-177 K AI-2E family transporter
HALMMDKM_00876 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HALMMDKM_00877 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HALMMDKM_00878 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HALMMDKM_00879 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HALMMDKM_00880 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HALMMDKM_00881 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HALMMDKM_00882 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HALMMDKM_00883 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HALMMDKM_00884 2e-85 L transposase, IS605 OrfB family
HALMMDKM_00885 1.2e-06 D nuclear chromosome segregation
HALMMDKM_00886 0.0 snf 2.7.11.1 KL domain protein
HALMMDKM_00887 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HALMMDKM_00888 2.2e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HALMMDKM_00889 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HALMMDKM_00890 5.4e-92 L nuclease
HALMMDKM_00891 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HALMMDKM_00892 3.3e-71
HALMMDKM_00893 7e-101 fic D Fic/DOC family
HALMMDKM_00894 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HALMMDKM_00895 7e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HALMMDKM_00896 1e-31
HALMMDKM_00897 1.7e-42
HALMMDKM_00898 1.8e-99
HALMMDKM_00899 7.1e-25
HALMMDKM_00900 6.6e-75 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_00901 5.3e-125 xylR GK ROK family
HALMMDKM_00902 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HALMMDKM_00903 8.1e-154 KT YcbB domain
HALMMDKM_00904 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HALMMDKM_00905 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HALMMDKM_00906 3.3e-161 EG EamA-like transporter family
HALMMDKM_00907 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HALMMDKM_00908 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HALMMDKM_00909 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HALMMDKM_00910 0.0 copA 3.6.3.54 P P-type ATPase
HALMMDKM_00911 1.7e-84
HALMMDKM_00913 5.2e-56
HALMMDKM_00915 1e-73 yjcE P Sodium proton antiporter
HALMMDKM_00916 2.7e-158 yjcE P Sodium proton antiporter
HALMMDKM_00918 3.5e-91 S Uncharacterised protein family (UPF0236)
HALMMDKM_00919 1.2e-252 clcA P chloride
HALMMDKM_00920 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HALMMDKM_00921 4.5e-104 proW P ABC transporter, permease protein
HALMMDKM_00922 1e-139 proV E ABC transporter, ATP-binding protein
HALMMDKM_00923 6.3e-109 proWZ P ABC transporter permease
HALMMDKM_00924 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HALMMDKM_00925 9e-75 K Transcriptional regulator
HALMMDKM_00926 4.8e-154 1.6.5.2 GM NAD(P)H-binding
HALMMDKM_00928 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
HALMMDKM_00929 0.0 cadA P P-type ATPase
HALMMDKM_00930 2.1e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HALMMDKM_00931 2.1e-126
HALMMDKM_00932 3.3e-55 S Sugar efflux transporter for intercellular exchange
HALMMDKM_00933 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HALMMDKM_00935 0.0 L Helicase C-terminal domain protein
HALMMDKM_00936 1.7e-74 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HALMMDKM_00937 2.6e-177 S Aldo keto reductase
HALMMDKM_00939 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HALMMDKM_00940 4.5e-62 psiE S Phosphate-starvation-inducible E
HALMMDKM_00941 2.1e-102 ydeN S Serine hydrolase
HALMMDKM_00943 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HALMMDKM_00944 4e-254 nhaC C Na H antiporter NhaC
HALMMDKM_00945 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HALMMDKM_00946 4.8e-114 ywnB S NAD(P)H-binding
HALMMDKM_00947 2.9e-37
HALMMDKM_00948 1.6e-129 IQ Dehydrogenase reductase
HALMMDKM_00949 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_00950 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HALMMDKM_00951 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HALMMDKM_00952 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HALMMDKM_00953 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HALMMDKM_00954 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HALMMDKM_00955 5.5e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HALMMDKM_00956 9.8e-67 yabR J RNA binding
HALMMDKM_00957 3.3e-56 divIC D Septum formation initiator
HALMMDKM_00958 8.1e-39 yabO J S4 domain protein
HALMMDKM_00959 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HALMMDKM_00960 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HALMMDKM_00961 4e-113 S (CBS) domain
HALMMDKM_00962 3.1e-147 tesE Q hydratase
HALMMDKM_00963 4.7e-243 codA 3.5.4.1 F cytosine deaminase
HALMMDKM_00964 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HALMMDKM_00965 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HALMMDKM_00966 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HALMMDKM_00967 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HALMMDKM_00969 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HALMMDKM_00970 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HALMMDKM_00971 8.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HALMMDKM_00972 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HALMMDKM_00973 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HALMMDKM_00974 8.4e-142 sprD D Domain of Unknown Function (DUF1542)
HALMMDKM_00975 4.5e-58
HALMMDKM_00976 3.9e-27 mleP3 S Membrane transport protein
HALMMDKM_00977 7.3e-121 T Transcriptional regulatory protein, C terminal
HALMMDKM_00978 9.9e-239 T GHKL domain
HALMMDKM_00979 4.7e-109 S Peptidase propeptide and YPEB domain
HALMMDKM_00980 1.7e-76 P FAD-binding domain
HALMMDKM_00981 4.3e-55 yphJ 4.1.1.44 S decarboxylase
HALMMDKM_00982 5.3e-83 K Bacterial regulatory proteins, tetR family
HALMMDKM_00983 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HALMMDKM_00984 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HALMMDKM_00985 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
HALMMDKM_00986 2.7e-85 C Flavodoxin
HALMMDKM_00987 5.6e-158 K Transcriptional regulator
HALMMDKM_00988 6.3e-88 lacA S transferase hexapeptide repeat
HALMMDKM_00989 9.4e-32 S thiolester hydrolase activity
HALMMDKM_00990 2e-152 S Alpha beta hydrolase
HALMMDKM_00991 2.3e-93 padC Q Phenolic acid decarboxylase
HALMMDKM_00992 3.3e-92 padR K Virulence activator alpha C-term
HALMMDKM_00993 4.7e-66 GM NAD(P)H-binding
HALMMDKM_00994 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HALMMDKM_00995 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HALMMDKM_00996 4.3e-59 K Transcriptional regulator
HALMMDKM_00997 4.3e-40 K Transcriptional regulator
HALMMDKM_00998 7.6e-163 akr5f 1.1.1.346 S reductase
HALMMDKM_00999 1.8e-104 K Transcriptional regulator C-terminal region
HALMMDKM_01000 1e-73 S membrane
HALMMDKM_01001 6.1e-88 S membrane
HALMMDKM_01002 1.2e-112 GM NAD(P)H-binding
HALMMDKM_01003 1.1e-64 yneR
HALMMDKM_01004 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
HALMMDKM_01005 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01006 5.6e-119 L Belongs to the 'phage' integrase family
HALMMDKM_01007 1.9e-10
HALMMDKM_01012 1.9e-101 M Glycosyl hydrolases family 25
HALMMDKM_01013 1.6e-27 cotH M CotH kinase protein
HALMMDKM_01014 7.6e-71
HALMMDKM_01015 1.4e-190 ganB 3.2.1.89 G arabinogalactan
HALMMDKM_01016 2.5e-152 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_01017 2.9e-90 L Transposase IS66 family
HALMMDKM_01018 6.6e-47 S dextransucrase activity
HALMMDKM_01019 1.1e-163 yueF S AI-2E family transporter
HALMMDKM_01020 1.8e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HALMMDKM_01021 7.5e-92 M Glycosyl transferase family 2
HALMMDKM_01022 1.3e-58
HALMMDKM_01023 1.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HALMMDKM_01024 2.1e-79 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01025 2.8e-255 yagE E amino acid
HALMMDKM_01026 3.4e-85 dps P Belongs to the Dps family
HALMMDKM_01027 0.0 pacL 3.6.3.8 P P-type ATPase
HALMMDKM_01028 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HALMMDKM_01029 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HALMMDKM_01030 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HALMMDKM_01031 4.5e-146 potB P ABC transporter permease
HALMMDKM_01032 4.9e-140 potC P ABC transporter permease
HALMMDKM_01033 4.3e-208 potD P ABC transporter
HALMMDKM_01034 8.1e-230
HALMMDKM_01035 7.2e-234 EGP Sugar (and other) transporter
HALMMDKM_01036 3e-254 yfnA E Amino Acid
HALMMDKM_01037 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HALMMDKM_01038 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
HALMMDKM_01039 1.5e-82 zur P Belongs to the Fur family
HALMMDKM_01040 4e-17 3.2.1.14 GH18
HALMMDKM_01041 7.1e-150
HALMMDKM_01042 5.8e-39 pspC KT PspC domain protein
HALMMDKM_01043 1.6e-94 K Transcriptional regulator (TetR family)
HALMMDKM_01044 4.8e-222 V domain protein
HALMMDKM_01045 2.9e-182 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HALMMDKM_01047 6.6e-35 S Transglycosylase associated protein
HALMMDKM_01048 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HALMMDKM_01049 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HALMMDKM_01050 1.2e-115 dedA S SNARE associated Golgi protein
HALMMDKM_01051 0.0 helD 3.6.4.12 L DNA helicase
HALMMDKM_01052 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HALMMDKM_01053 4.7e-157 EG EamA-like transporter family
HALMMDKM_01054 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HALMMDKM_01055 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HALMMDKM_01056 1.5e-225 S cog cog1373
HALMMDKM_01058 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HALMMDKM_01059 1.9e-24
HALMMDKM_01060 0.0 L helicase
HALMMDKM_01061 6e-109 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01062 4.5e-64 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01063 1.3e-226 aadAT EK Aminotransferase, class I
HALMMDKM_01064 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HALMMDKM_01065 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HALMMDKM_01066 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HALMMDKM_01067 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HALMMDKM_01068 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HALMMDKM_01069 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HALMMDKM_01070 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HALMMDKM_01071 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HALMMDKM_01072 1.7e-207 yacL S domain protein
HALMMDKM_01073 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HALMMDKM_01074 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HALMMDKM_01075 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HALMMDKM_01076 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HALMMDKM_01077 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HALMMDKM_01078 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HALMMDKM_01079 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_01080 2.4e-119 tcyB E ABC transporter
HALMMDKM_01081 3.6e-213 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HALMMDKM_01082 3.1e-169 I alpha/beta hydrolase fold
HALMMDKM_01083 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HALMMDKM_01084 0.0 S Bacterial membrane protein, YfhO
HALMMDKM_01085 4.5e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HALMMDKM_01086 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HALMMDKM_01088 1.9e-85 ydcK S Belongs to the SprT family
HALMMDKM_01089 0.0 yhgF K Tex-like protein N-terminal domain protein
HALMMDKM_01090 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HALMMDKM_01091 1.3e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HALMMDKM_01092 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HALMMDKM_01093 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HALMMDKM_01094 9.5e-300 aspT P Predicted Permease Membrane Region
HALMMDKM_01095 2.8e-252 EGP Major facilitator Superfamily
HALMMDKM_01096 5.5e-110
HALMMDKM_01099 1.4e-158 yjjH S Calcineurin-like phosphoesterase
HALMMDKM_01100 5e-263 dtpT U amino acid peptide transporter
HALMMDKM_01101 3.7e-19
HALMMDKM_01103 1.1e-90 yqiG C Oxidoreductase
HALMMDKM_01104 3.4e-85 yqiG C Oxidoreductase
HALMMDKM_01105 4.5e-55 S macrophage migration inhibitory factor
HALMMDKM_01106 2.4e-65 K HxlR-like helix-turn-helix
HALMMDKM_01107 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HALMMDKM_01109 7.1e-195 L Transposase IS66 family
HALMMDKM_01110 4.9e-33 L PFAM Integrase catalytic region
HALMMDKM_01111 2.1e-88 L Transposase
HALMMDKM_01112 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HALMMDKM_01113 1.6e-105 ypsA S Belongs to the UPF0398 family
HALMMDKM_01114 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HALMMDKM_01115 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HALMMDKM_01116 2e-161 EG EamA-like transporter family
HALMMDKM_01117 3e-125 dnaD L DnaD domain protein
HALMMDKM_01118 2.9e-85 ypmB S Protein conserved in bacteria
HALMMDKM_01119 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HALMMDKM_01120 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HALMMDKM_01121 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HALMMDKM_01122 1.2e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HALMMDKM_01123 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HALMMDKM_01124 3.8e-87 S Protein of unknown function (DUF1440)
HALMMDKM_01125 0.0 rafA 3.2.1.22 G alpha-galactosidase
HALMMDKM_01126 4.2e-189 galR K Periplasmic binding protein-like domain
HALMMDKM_01127 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HALMMDKM_01128 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HALMMDKM_01129 2.6e-124 lrgB M LrgB-like family
HALMMDKM_01130 1.9e-66 lrgA S LrgA family
HALMMDKM_01131 5.1e-66 lytT K response regulator receiver
HALMMDKM_01132 2.2e-75 L hmm pf00665
HALMMDKM_01133 1.7e-202 2.7.7.65 T GGDEF domain
HALMMDKM_01134 1.3e-111 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HALMMDKM_01135 1.7e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HALMMDKM_01136 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HALMMDKM_01137 2e-92 folT S ECF transporter, substrate-specific component
HALMMDKM_01138 0.0 pepN 3.4.11.2 E aminopeptidase
HALMMDKM_01139 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HALMMDKM_01140 9.8e-255 pepC 3.4.22.40 E aminopeptidase
HALMMDKM_01141 6.5e-210 EGP Major facilitator Superfamily
HALMMDKM_01142 1.8e-229
HALMMDKM_01143 3.5e-79 K Transcriptional regulator, HxlR family
HALMMDKM_01144 3.7e-108 XK27_02070 S Nitroreductase family
HALMMDKM_01145 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HALMMDKM_01146 3e-119 GM NmrA-like family
HALMMDKM_01147 1.7e-70 elaA S Gnat family
HALMMDKM_01148 1.8e-39 S Cytochrome B5
HALMMDKM_01149 5.4e-09 S Cytochrome B5
HALMMDKM_01150 7.8e-41 S Cytochrome B5
HALMMDKM_01151 2.6e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
HALMMDKM_01153 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HALMMDKM_01154 6.4e-241 E amino acid
HALMMDKM_01155 1.8e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
HALMMDKM_01156 3.1e-226 yxiO S Vacuole effluxer Atg22 like
HALMMDKM_01158 4.5e-102 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HALMMDKM_01159 1.8e-39
HALMMDKM_01160 1.3e-129 1.1.1.100 I Enoyl-(Acyl carrier protein) reductase
HALMMDKM_01161 4.4e-171 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HALMMDKM_01162 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HALMMDKM_01163 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
HALMMDKM_01164 2.8e-207 araR K Transcriptional regulator
HALMMDKM_01165 4.3e-83 usp6 T universal stress protein
HALMMDKM_01166 4.4e-46
HALMMDKM_01167 1.7e-235 rarA L recombination factor protein RarA
HALMMDKM_01168 7.1e-86 yueI S Protein of unknown function (DUF1694)
HALMMDKM_01169 1.5e-21
HALMMDKM_01170 1.4e-74 4.4.1.5 E Glyoxalase
HALMMDKM_01171 2.5e-138 S Membrane
HALMMDKM_01172 2.5e-135 S Belongs to the UPF0246 family
HALMMDKM_01173 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HALMMDKM_01174 2e-260 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HALMMDKM_01175 1.1e-235 pbuG S permease
HALMMDKM_01176 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HALMMDKM_01177 3.3e-46 gcvH E glycine cleavage
HALMMDKM_01178 4.1e-220 rodA D Belongs to the SEDS family
HALMMDKM_01179 1e-31 S Protein of unknown function (DUF2969)
HALMMDKM_01180 2.9e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HALMMDKM_01181 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HALMMDKM_01182 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HALMMDKM_01183 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HALMMDKM_01184 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HALMMDKM_01185 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HALMMDKM_01186 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HALMMDKM_01187 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HALMMDKM_01188 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HALMMDKM_01189 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HALMMDKM_01190 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HALMMDKM_01191 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HALMMDKM_01192 5e-232 pyrP F Permease
HALMMDKM_01193 6.3e-129 yibF S overlaps another CDS with the same product name
HALMMDKM_01194 9.9e-192 yibE S overlaps another CDS with the same product name
HALMMDKM_01195 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HALMMDKM_01196 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HALMMDKM_01197 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HALMMDKM_01198 1e-57
HALMMDKM_01199 6.4e-39 S GyrI-like small molecule binding domain
HALMMDKM_01200 5e-122 yhiD S MgtC family
HALMMDKM_01201 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HALMMDKM_01202 3.8e-190 V Beta-lactamase
HALMMDKM_01203 7e-41 ybaN S Protein of unknown function (DUF454)
HALMMDKM_01204 9.1e-72 S Protein of unknown function (DUF3290)
HALMMDKM_01205 6.2e-114 yviA S Protein of unknown function (DUF421)
HALMMDKM_01206 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HALMMDKM_01207 1.3e-20
HALMMDKM_01208 8.1e-90 ntd 2.4.2.6 F Nucleoside
HALMMDKM_01209 9.5e-155 3.1.3.102, 3.1.3.104 S hydrolase
HALMMDKM_01210 1.6e-45 yrvD S Pfam:DUF1049
HALMMDKM_01212 1.1e-35 S Phage derived protein Gp49-like (DUF891)
HALMMDKM_01213 8.5e-20 K Helix-turn-helix XRE-family like proteins
HALMMDKM_01214 1.7e-78 I alpha/beta hydrolase fold
HALMMDKM_01215 1.1e-113 frnE Q DSBA-like thioredoxin domain
HALMMDKM_01216 1.4e-51
HALMMDKM_01217 3.4e-149 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_01218 2.1e-60 L PFAM transposase IS200-family protein
HALMMDKM_01220 0.0 L PLD-like domain
HALMMDKM_01221 1.1e-34 higA K addiction module antidote protein HigA
HALMMDKM_01222 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HALMMDKM_01223 4.7e-51 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HALMMDKM_01224 4e-300 2.1.1.72 V type I restriction-modification system
HALMMDKM_01225 5.8e-178 yfjM S Protein of unknown function DUF262
HALMMDKM_01226 3.1e-57 yhaI S Protein of unknown function (DUF805)
HALMMDKM_01227 2.2e-44
HALMMDKM_01228 2.4e-22
HALMMDKM_01229 5.4e-47
HALMMDKM_01230 2.9e-96 K Acetyltransferase (GNAT) domain
HALMMDKM_01231 3.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HALMMDKM_01232 5.9e-147 gntT EG Gluconate
HALMMDKM_01233 6e-65 gntT EG Gluconate
HALMMDKM_01234 3.8e-182 K Transcriptional regulator, LacI family
HALMMDKM_01235 1.8e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HALMMDKM_01236 3.2e-95
HALMMDKM_01237 2.1e-25
HALMMDKM_01238 1.3e-61 asp S Asp23 family, cell envelope-related function
HALMMDKM_01239 1.2e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HALMMDKM_01241 2.7e-49
HALMMDKM_01242 1.6e-67 yqkB S Belongs to the HesB IscA family
HALMMDKM_01243 7.6e-91 L PFAM Integrase catalytic region
HALMMDKM_01244 7.4e-49 M KxYKxGKxW signal domain protein
HALMMDKM_01245 2.3e-34
HALMMDKM_01246 6.6e-84 M biosynthesis protein
HALMMDKM_01247 2.5e-185 cps3F
HALMMDKM_01248 6.9e-102 S enterobacterial common antigen metabolic process
HALMMDKM_01250 2.3e-100 acmD M repeat protein
HALMMDKM_01251 2.8e-132 M transferase activity, transferring glycosyl groups
HALMMDKM_01252 8.8e-150 waaB GT4 M Glycosyl transferases group 1
HALMMDKM_01253 8.1e-239 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HALMMDKM_01254 5.8e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
HALMMDKM_01255 4.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
HALMMDKM_01256 1.7e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HALMMDKM_01257 3.3e-146 cps1D M Domain of unknown function (DUF4422)
HALMMDKM_01258 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
HALMMDKM_01259 4.9e-31
HALMMDKM_01260 6.6e-34 S Protein of unknown function (DUF2922)
HALMMDKM_01261 3.2e-153 yihY S Belongs to the UPF0761 family
HALMMDKM_01262 4.1e-281 yjeM E Amino Acid
HALMMDKM_01263 6.1e-255 E Arginine ornithine antiporter
HALMMDKM_01264 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HALMMDKM_01265 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HALMMDKM_01266 6.1e-79 fld C Flavodoxin
HALMMDKM_01267 2.3e-67 gtcA S Teichoic acid glycosylation protein
HALMMDKM_01268 4.2e-71 S Uncharacterised protein family (UPF0236)
HALMMDKM_01269 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HALMMDKM_01270 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HALMMDKM_01271 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HALMMDKM_01272 3e-203 coiA 3.6.4.12 S Competence protein
HALMMDKM_01273 9.2e-264 pipD E Dipeptidase
HALMMDKM_01274 4.7e-114 yjbH Q Thioredoxin
HALMMDKM_01275 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HALMMDKM_01276 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HALMMDKM_01277 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HALMMDKM_01278 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HALMMDKM_01279 1.6e-54 ysxB J Cysteine protease Prp
HALMMDKM_01280 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HALMMDKM_01281 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HALMMDKM_01282 7.8e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HALMMDKM_01283 8.6e-114 J 2'-5' RNA ligase superfamily
HALMMDKM_01284 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HALMMDKM_01285 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HALMMDKM_01286 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HALMMDKM_01287 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HALMMDKM_01288 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HALMMDKM_01289 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HALMMDKM_01290 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HALMMDKM_01291 3.3e-77 argR K Regulates arginine biosynthesis genes
HALMMDKM_01292 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
HALMMDKM_01293 1.7e-54
HALMMDKM_01294 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HALMMDKM_01295 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HALMMDKM_01296 6.2e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HALMMDKM_01297 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HALMMDKM_01298 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HALMMDKM_01299 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HALMMDKM_01300 4.2e-130 stp 3.1.3.16 T phosphatase
HALMMDKM_01301 0.0 KLT serine threonine protein kinase
HALMMDKM_01302 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HALMMDKM_01303 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HALMMDKM_01304 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HALMMDKM_01305 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HALMMDKM_01306 4.7e-58 asp S Asp23 family, cell envelope-related function
HALMMDKM_01307 7.1e-311 yloV S DAK2 domain fusion protein YloV
HALMMDKM_01308 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HALMMDKM_01309 1.6e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HALMMDKM_01310 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HALMMDKM_01311 1.6e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HALMMDKM_01312 0.0 smc D Required for chromosome condensation and partitioning
HALMMDKM_01313 9.4e-185 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HALMMDKM_01314 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HALMMDKM_01315 1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HALMMDKM_01316 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HALMMDKM_01317 2e-39 ylqC S Belongs to the UPF0109 family
HALMMDKM_01318 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HALMMDKM_01319 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HALMMDKM_01320 6.8e-262 yfnA E amino acid
HALMMDKM_01321 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HALMMDKM_01322 2.9e-34
HALMMDKM_01323 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
HALMMDKM_01324 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HALMMDKM_01325 3.3e-83
HALMMDKM_01326 3.8e-153 L PFAM Integrase catalytic region
HALMMDKM_01329 1.1e-19 M LPXTG-motif cell wall anchor domain protein
HALMMDKM_01330 0.0 M LPXTG-motif cell wall anchor domain protein
HALMMDKM_01331 4e-182 M LPXTG-motif cell wall anchor domain protein
HALMMDKM_01332 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HALMMDKM_01333 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
HALMMDKM_01334 2.8e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HALMMDKM_01335 3.9e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HALMMDKM_01338 2.5e-185 L transposase, IS605 OrfB family
HALMMDKM_01339 2.1e-50 L Transposase IS200 like
HALMMDKM_01340 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HALMMDKM_01341 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HALMMDKM_01342 3.1e-223 mdtG EGP Major facilitator Superfamily
HALMMDKM_01343 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HALMMDKM_01344 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HALMMDKM_01345 1.8e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HALMMDKM_01346 1.4e-95 L PFAM Integrase catalytic region
HALMMDKM_01347 3.7e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HALMMDKM_01348 3.1e-103 metI P ABC transporter permease
HALMMDKM_01349 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HALMMDKM_01350 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HALMMDKM_01351 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HALMMDKM_01352 1.5e-115 L PFAM Integrase catalytic region
HALMMDKM_01353 3.9e-66
HALMMDKM_01354 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HALMMDKM_01355 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HALMMDKM_01356 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HALMMDKM_01357 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMMDKM_01358 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMMDKM_01359 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HALMMDKM_01360 1.1e-62 rplQ J Ribosomal protein L17
HALMMDKM_01361 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HALMMDKM_01362 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HALMMDKM_01363 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HALMMDKM_01364 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HALMMDKM_01365 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HALMMDKM_01366 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HALMMDKM_01367 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HALMMDKM_01368 8.9e-64 rplO J Binds to the 23S rRNA
HALMMDKM_01369 2.9e-24 rpmD J Ribosomal protein L30
HALMMDKM_01370 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HALMMDKM_01371 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HALMMDKM_01372 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HALMMDKM_01373 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HALMMDKM_01374 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HALMMDKM_01375 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HALMMDKM_01376 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HALMMDKM_01377 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HALMMDKM_01378 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HALMMDKM_01379 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HALMMDKM_01380 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HALMMDKM_01381 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HALMMDKM_01382 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HALMMDKM_01383 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HALMMDKM_01384 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HALMMDKM_01385 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HALMMDKM_01386 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HALMMDKM_01387 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HALMMDKM_01388 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HALMMDKM_01389 2.2e-82
HALMMDKM_01390 9.5e-29 L PFAM Integrase catalytic region
HALMMDKM_01391 9.8e-53 L PFAM Integrase catalytic region
HALMMDKM_01392 2.7e-26 K TRANSCRIPTIONal
HALMMDKM_01393 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
HALMMDKM_01394 5.6e-79 pncA Q Isochorismatase family
HALMMDKM_01395 1.2e-229 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HALMMDKM_01396 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
HALMMDKM_01397 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01398 3.9e-105 K Transcriptional regulator
HALMMDKM_01402 2.5e-89 dut S Protein conserved in bacteria
HALMMDKM_01403 6.6e-174
HALMMDKM_01404 1e-151
HALMMDKM_01405 3.7e-51 S Iron-sulfur cluster assembly protein
HALMMDKM_01406 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HALMMDKM_01407 3.1e-153 P Belongs to the nlpA lipoprotein family
HALMMDKM_01408 3.9e-12
HALMMDKM_01409 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HALMMDKM_01410 8.4e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HALMMDKM_01411 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
HALMMDKM_01412 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HALMMDKM_01413 1.3e-21 S Protein of unknown function (DUF3042)
HALMMDKM_01414 7.2e-71 yqhL P Rhodanese-like protein
HALMMDKM_01415 5.6e-183 glk 2.7.1.2 G Glucokinase
HALMMDKM_01416 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HALMMDKM_01417 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
HALMMDKM_01418 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
HALMMDKM_01419 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HALMMDKM_01420 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HALMMDKM_01421 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HALMMDKM_01422 0.0 S membrane
HALMMDKM_01423 8.8e-71 yneR S Belongs to the HesB IscA family
HALMMDKM_01424 3.3e-85 L PFAM transposase IS200-family protein
HALMMDKM_01425 9e-124 L PFAM Integrase catalytic region
HALMMDKM_01426 5.9e-30 2.7.13.3 T GHKL domain
HALMMDKM_01429 1.3e-260 S Putative peptidoglycan binding domain
HALMMDKM_01430 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HALMMDKM_01431 1.1e-217 ecsB U ABC transporter
HALMMDKM_01432 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HALMMDKM_01433 1.2e-76 hit FG histidine triad
HALMMDKM_01435 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HALMMDKM_01436 0.0 L AAA domain
HALMMDKM_01437 1.8e-220 yhaO L Ser Thr phosphatase family protein
HALMMDKM_01438 3.5e-40 yheA S Belongs to the UPF0342 family
HALMMDKM_01439 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HALMMDKM_01440 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HALMMDKM_01441 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HALMMDKM_01442 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HALMMDKM_01444 3.3e-40
HALMMDKM_01445 1.8e-43
HALMMDKM_01446 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
HALMMDKM_01447 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HALMMDKM_01448 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HALMMDKM_01449 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HALMMDKM_01450 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HALMMDKM_01451 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HALMMDKM_01453 1.9e-43
HALMMDKM_01454 4.5e-112 S CAAX protease self-immunity
HALMMDKM_01455 2.1e-32
HALMMDKM_01456 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HALMMDKM_01457 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HALMMDKM_01458 3.8e-113
HALMMDKM_01459 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HALMMDKM_01460 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HALMMDKM_01461 1.2e-85 uspA T Belongs to the universal stress protein A family
HALMMDKM_01462 4.3e-277 pepV 3.5.1.18 E dipeptidase PepV
HALMMDKM_01463 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HALMMDKM_01464 4.1e-303 ytgP S Polysaccharide biosynthesis protein
HALMMDKM_01465 4.9e-41
HALMMDKM_01466 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HALMMDKM_01467 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HALMMDKM_01468 9.6e-92 tag 3.2.2.20 L glycosylase
HALMMDKM_01469 1.5e-253 EGP Major facilitator Superfamily
HALMMDKM_01470 4.3e-85 perR P Belongs to the Fur family
HALMMDKM_01471 4.8e-233 cycA E Amino acid permease
HALMMDKM_01472 2.8e-102 V VanZ like family
HALMMDKM_01473 1e-23
HALMMDKM_01474 5e-85 S Short repeat of unknown function (DUF308)
HALMMDKM_01475 2.9e-78 S Psort location Cytoplasmic, score
HALMMDKM_01476 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HALMMDKM_01477 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HALMMDKM_01478 8.1e-154 yeaE S Aldo keto
HALMMDKM_01479 2.3e-93 lytE M LysM domain protein
HALMMDKM_01480 0.0 oppD EP Psort location Cytoplasmic, score
HALMMDKM_01481 2.6e-80 lytE M LysM domain protein
HALMMDKM_01482 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
HALMMDKM_01483 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HALMMDKM_01484 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HALMMDKM_01485 1.5e-237 lmrB EGP Major facilitator Superfamily
HALMMDKM_01486 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HALMMDKM_01487 9.8e-42 L Transposase IS66 family
HALMMDKM_01488 2.5e-97 O Arylsulfotransferase (ASST)
HALMMDKM_01489 2.8e-131 O Arylsulfotransferase (ASST)
HALMMDKM_01490 1.3e-168 L Belongs to the 'phage' integrase family
HALMMDKM_01491 6.9e-19 S Excisionase from transposon Tn916
HALMMDKM_01494 5.7e-154
HALMMDKM_01496 1.6e-76 L Resolvase, N terminal domain
HALMMDKM_01497 3.7e-10 L Resolvase, N terminal domain
HALMMDKM_01498 7e-12 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HALMMDKM_01499 3.1e-127 L Transposase and inactivated derivatives IS30 family
HALMMDKM_01500 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HALMMDKM_01501 2.7e-39 ptsH G phosphocarrier protein HPR
HALMMDKM_01502 2.9e-27
HALMMDKM_01503 0.0 clpE O Belongs to the ClpA ClpB family
HALMMDKM_01504 2.4e-99 S Pfam:DUF3816
HALMMDKM_01505 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HALMMDKM_01506 6.7e-114
HALMMDKM_01507 3.3e-158 V ABC transporter, ATP-binding protein
HALMMDKM_01508 7.9e-64 gntR1 K Transcriptional regulator, GntR family
HALMMDKM_01509 1.9e-106 L PFAM Integrase catalytic region
HALMMDKM_01510 1.5e-50 UW LPXTG-motif cell wall anchor domain protein
HALMMDKM_01511 4.6e-61 L Transposase
HALMMDKM_01512 5.4e-53 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01513 2.8e-93 L PFAM Integrase catalytic region
HALMMDKM_01514 2.3e-15
HALMMDKM_01515 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HALMMDKM_01517 0.0 L helicase activity
HALMMDKM_01518 2.1e-217 K DNA binding
HALMMDKM_01519 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
HALMMDKM_01520 1.9e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
HALMMDKM_01522 4.4e-17
HALMMDKM_01523 1.5e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HALMMDKM_01524 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HALMMDKM_01525 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HALMMDKM_01526 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HALMMDKM_01527 7e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HALMMDKM_01528 2.1e-202 camS S sex pheromone
HALMMDKM_01529 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HALMMDKM_01530 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HALMMDKM_01531 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HALMMDKM_01532 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HALMMDKM_01533 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HALMMDKM_01534 3.6e-140 IQ reductase
HALMMDKM_01535 2.1e-08 L Transposase
HALMMDKM_01536 6.6e-262 S Putative peptidoglycan binding domain
HALMMDKM_01537 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HALMMDKM_01538 2.2e-87
HALMMDKM_01539 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HALMMDKM_01540 2.6e-214 yttB EGP Major facilitator Superfamily
HALMMDKM_01541 8.2e-103
HALMMDKM_01542 5.1e-116 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01543 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HALMMDKM_01544 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HALMMDKM_01545 5.6e-115 rlpA M PFAM NLP P60 protein
HALMMDKM_01546 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HALMMDKM_01547 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HALMMDKM_01548 2e-58 yodB K Transcriptional regulator, HxlR family
HALMMDKM_01549 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HALMMDKM_01550 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HALMMDKM_01551 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HALMMDKM_01552 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HALMMDKM_01553 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HALMMDKM_01554 1.4e-229 V MatE
HALMMDKM_01555 7.4e-267 yjeM E Amino Acid
HALMMDKM_01556 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HALMMDKM_01557 1.5e-121 K response regulator
HALMMDKM_01558 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HALMMDKM_01559 2.9e-99 yceD S Uncharacterized ACR, COG1399
HALMMDKM_01560 2.1e-213 ylbM S Belongs to the UPF0348 family
HALMMDKM_01561 1.7e-139 yqeM Q Methyltransferase
HALMMDKM_01562 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HALMMDKM_01563 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HALMMDKM_01564 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HALMMDKM_01565 1.9e-47 yhbY J RNA-binding protein
HALMMDKM_01566 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
HALMMDKM_01567 1.8e-95 yqeG S HAD phosphatase, family IIIA
HALMMDKM_01568 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HALMMDKM_01569 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HALMMDKM_01570 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HALMMDKM_01571 2.4e-170 dnaI L Primosomal protein DnaI
HALMMDKM_01572 2.4e-200 dnaB L replication initiation and membrane attachment
HALMMDKM_01573 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HALMMDKM_01574 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HALMMDKM_01575 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HALMMDKM_01576 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HALMMDKM_01577 4.1e-116 yoaK S Protein of unknown function (DUF1275)
HALMMDKM_01578 5.5e-119 ybhL S Belongs to the BI1 family
HALMMDKM_01579 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HALMMDKM_01580 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HALMMDKM_01581 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HALMMDKM_01582 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HALMMDKM_01583 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HALMMDKM_01584 7.5e-58 ytzB S Small secreted protein
HALMMDKM_01585 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
HALMMDKM_01586 4.3e-183 iolS C Aldo keto reductase
HALMMDKM_01587 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HALMMDKM_01588 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HALMMDKM_01589 4.7e-255 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HALMMDKM_01590 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HALMMDKM_01591 7.7e-27 S YSIRK type signal peptide
HALMMDKM_01592 1.4e-38 L PFAM Integrase catalytic region
HALMMDKM_01593 6.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HALMMDKM_01594 3.9e-93 dps P Belongs to the Dps family
HALMMDKM_01595 7.9e-35 copZ C Heavy-metal-associated domain
HALMMDKM_01596 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HALMMDKM_01597 3.1e-59 L PFAM Integrase catalytic region
HALMMDKM_01598 1.5e-89 L hmm pf00665
HALMMDKM_01600 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HALMMDKM_01601 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HALMMDKM_01602 8.5e-117 O Zinc-dependent metalloprotease
HALMMDKM_01603 4.1e-115 S Membrane
HALMMDKM_01604 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HALMMDKM_01605 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HALMMDKM_01606 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HALMMDKM_01607 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HALMMDKM_01608 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HALMMDKM_01609 3.2e-40 yggT S YGGT family
HALMMDKM_01610 5.1e-142 ylmH S S4 domain protein
HALMMDKM_01611 1.9e-42 divIVA D DivIVA domain protein
HALMMDKM_01612 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HALMMDKM_01613 4.2e-32 cspA K Cold shock protein
HALMMDKM_01614 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HALMMDKM_01616 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HALMMDKM_01617 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
HALMMDKM_01618 1.3e-57 XK27_04120 S Putative amino acid metabolism
HALMMDKM_01619 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HALMMDKM_01620 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HALMMDKM_01621 9e-119 S Repeat protein
HALMMDKM_01622 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HALMMDKM_01623 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HALMMDKM_01624 2.3e-08 L Helix-turn-helix domain
HALMMDKM_01625 1.4e-52 L transposase, IS605 OrfB family
HALMMDKM_01626 1.5e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HALMMDKM_01627 1.8e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HALMMDKM_01628 2.3e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HALMMDKM_01629 2.9e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HALMMDKM_01630 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HALMMDKM_01631 4.7e-102 T Ion transport 2 domain protein
HALMMDKM_01632 0.0 S Bacterial membrane protein YfhO
HALMMDKM_01633 5e-202 G Transporter, major facilitator family protein
HALMMDKM_01634 2.4e-109 yvrI K sigma factor activity
HALMMDKM_01635 3.5e-64 ydiI Q Thioesterase superfamily
HALMMDKM_01636 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HALMMDKM_01637 2.5e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HALMMDKM_01638 5.5e-19
HALMMDKM_01639 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HALMMDKM_01640 4.2e-32 feoA P FeoA domain
HALMMDKM_01641 6.5e-145 sufC O FeS assembly ATPase SufC
HALMMDKM_01642 7.3e-239 sufD O FeS assembly protein SufD
HALMMDKM_01643 7.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HALMMDKM_01644 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HALMMDKM_01645 1.6e-271 sufB O assembly protein SufB
HALMMDKM_01646 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HALMMDKM_01647 6.1e-160 hipB K Helix-turn-helix
HALMMDKM_01648 9.8e-115 nreC K PFAM regulatory protein LuxR
HALMMDKM_01649 9.2e-39 S Cytochrome B5
HALMMDKM_01650 2.2e-156 yitU 3.1.3.104 S hydrolase
HALMMDKM_01651 1.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HALMMDKM_01652 8.9e-148 f42a O Band 7 protein
HALMMDKM_01653 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HALMMDKM_01654 5.2e-47 lytT K response regulator receiver
HALMMDKM_01656 4.5e-58
HALMMDKM_01657 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HALMMDKM_01658 5.5e-158 endA V DNA/RNA non-specific endonuclease
HALMMDKM_01659 1e-254 yifK E Amino acid permease
HALMMDKM_01661 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HALMMDKM_01662 3e-229 N Uncharacterized conserved protein (DUF2075)
HALMMDKM_01663 4.6e-123 S SNARE associated Golgi protein
HALMMDKM_01664 0.0 uvrA3 L excinuclease ABC, A subunit
HALMMDKM_01665 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HALMMDKM_01666 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HALMMDKM_01667 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HALMMDKM_01668 9.6e-144 S DUF218 domain
HALMMDKM_01669 0.0 ubiB S ABC1 family
HALMMDKM_01670 2.5e-245 yhdP S Transporter associated domain
HALMMDKM_01671 5.5e-74 copY K Copper transport repressor CopY TcrY
HALMMDKM_01672 2.1e-244 EGP Major facilitator Superfamily
HALMMDKM_01673 1e-73 yeaL S UPF0756 membrane protein
HALMMDKM_01674 5.6e-79 yphH S Cupin domain
HALMMDKM_01675 3.2e-83 C Flavodoxin
HALMMDKM_01676 1.1e-158 K LysR substrate binding domain protein
HALMMDKM_01677 1.7e-170 1.1.1.346 C Aldo keto reductase
HALMMDKM_01678 2.1e-39 gcvR T Belongs to the UPF0237 family
HALMMDKM_01679 1e-238 XK27_08635 S UPF0210 protein
HALMMDKM_01680 1.5e-94 K Acetyltransferase (GNAT) domain
HALMMDKM_01681 1.2e-160 S Alpha beta hydrolase
HALMMDKM_01682 1.1e-158 gspA M family 8
HALMMDKM_01683 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HALMMDKM_01684 3.8e-93
HALMMDKM_01685 1.9e-161 degV S EDD domain protein, DegV family
HALMMDKM_01686 0.0 FbpA K Fibronectin-binding protein
HALMMDKM_01687 1.3e-151 L Transposase
HALMMDKM_01688 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HALMMDKM_01689 6.1e-198 XK27_09615 S reductase
HALMMDKM_01690 1.2e-100 nqr 1.5.1.36 S reductase
HALMMDKM_01692 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HALMMDKM_01693 2.4e-181 K Transcriptional regulator, LacI family
HALMMDKM_01694 1e-259 G Major Facilitator
HALMMDKM_01695 3.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HALMMDKM_01696 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HALMMDKM_01697 9.2e-264 G Major Facilitator
HALMMDKM_01698 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HALMMDKM_01699 9.2e-277 M domain protein
HALMMDKM_01700 7e-95 L PFAM Integrase catalytic region
HALMMDKM_01701 3.2e-96 S PFAM Archaeal ATPase
HALMMDKM_01702 1.3e-46
HALMMDKM_01704 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HALMMDKM_01705 9.4e-159 amtB P ammonium transporter
HALMMDKM_01706 4e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HALMMDKM_01707 1.4e-90 S B3 4 domain
HALMMDKM_01708 2.1e-91
HALMMDKM_01709 1.1e-69 pnb C nitroreductase
HALMMDKM_01710 2.2e-57
HALMMDKM_01711 5.8e-64
HALMMDKM_01712 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HALMMDKM_01713 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HALMMDKM_01714 0.0 dnaK O Heat shock 70 kDa protein
HALMMDKM_01715 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HALMMDKM_01716 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HALMMDKM_01717 4.1e-275 pipD E Dipeptidase
HALMMDKM_01718 4.7e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HALMMDKM_01720 5.7e-62
HALMMDKM_01721 1.3e-79 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01722 9.3e-56
HALMMDKM_01723 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HALMMDKM_01725 2.2e-227 yfmL L DEAD DEAH box helicase
HALMMDKM_01726 4.5e-191 mocA S Oxidoreductase
HALMMDKM_01727 9.1e-62 S Domain of unknown function (DUF4828)
HALMMDKM_01728 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HALMMDKM_01729 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HALMMDKM_01730 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HALMMDKM_01731 9.3e-197 S Protein of unknown function (DUF3114)
HALMMDKM_01732 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HALMMDKM_01733 1.1e-119 ybhL S Belongs to the BI1 family
HALMMDKM_01734 3.1e-21
HALMMDKM_01735 2e-91 K Acetyltransferase (GNAT) family
HALMMDKM_01736 6.4e-78 K LytTr DNA-binding domain
HALMMDKM_01737 7.3e-69 S Protein of unknown function (DUF3021)
HALMMDKM_01738 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HALMMDKM_01739 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
HALMMDKM_01740 2e-74 ogt 2.1.1.63 L Methyltransferase
HALMMDKM_01741 1.9e-43 pnb C nitroreductase
HALMMDKM_01742 3.9e-116 L Transposase and inactivated derivatives IS30 family
HALMMDKM_01747 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HALMMDKM_01748 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HALMMDKM_01749 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HALMMDKM_01750 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HALMMDKM_01751 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HALMMDKM_01752 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HALMMDKM_01753 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HALMMDKM_01754 4.2e-130 IQ reductase
HALMMDKM_01755 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HALMMDKM_01756 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HALMMDKM_01757 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HALMMDKM_01758 2.6e-68 marR K Transcriptional regulator, MarR family
HALMMDKM_01759 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HALMMDKM_01761 9.6e-200 xerS L Belongs to the 'phage' integrase family
HALMMDKM_01763 2.6e-191 nss M transferase activity, transferring glycosyl groups
HALMMDKM_01764 2.8e-144 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HALMMDKM_01765 2.6e-195 M transferase activity, transferring glycosyl groups
HALMMDKM_01766 3.1e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HALMMDKM_01767 1.3e-154 asp3 S Accessory Sec secretory system ASP3
HALMMDKM_01768 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HALMMDKM_01769 1.1e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HALMMDKM_01770 7.9e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HALMMDKM_01772 4e-92 L PFAM Integrase catalytic region
HALMMDKM_01773 9.9e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HALMMDKM_01774 4.2e-158 rssA S Phospholipase, patatin family
HALMMDKM_01775 2.5e-118 L Integrase
HALMMDKM_01776 1.2e-152 EG EamA-like transporter family
HALMMDKM_01777 1.5e-16 L Integrase core domain
HALMMDKM_01778 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HALMMDKM_01780 2.8e-57
HALMMDKM_01781 7e-178 prmA J Ribosomal protein L11 methyltransferase
HALMMDKM_01782 4.6e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HALMMDKM_01783 1.2e-52
HALMMDKM_01784 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HALMMDKM_01785 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HALMMDKM_01786 2.1e-165 yniA G Phosphotransferase enzyme family
HALMMDKM_01787 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HALMMDKM_01788 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_01789 9.1e-265 glnPH2 P ABC transporter permease
HALMMDKM_01790 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HALMMDKM_01791 3.8e-70 yqeY S YqeY-like protein
HALMMDKM_01792 9.6e-61 L PFAM transposase IS200-family protein
HALMMDKM_01793 4e-28
HALMMDKM_01794 5.4e-101 K DNA-templated transcription, initiation
HALMMDKM_01795 2.8e-35
HALMMDKM_01796 4.8e-85
HALMMDKM_01797 3.1e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HALMMDKM_01798 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HALMMDKM_01799 0.0 yjbQ P TrkA C-terminal domain protein
HALMMDKM_01800 6.7e-278 pipD E Dipeptidase
HALMMDKM_01801 4.4e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01808 2.9e-90 L Transposase IS66 family
HALMMDKM_01809 9.6e-73 L PFAM Integrase catalytic region
HALMMDKM_01810 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HALMMDKM_01811 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HALMMDKM_01812 3.9e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HALMMDKM_01813 6.3e-227 clcA_2 P Chloride transporter, ClC family
HALMMDKM_01814 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HALMMDKM_01815 1.4e-110 lssY 3.6.1.27 I Acid phosphatase homologues
HALMMDKM_01816 5.9e-123 L Transposase IS66 family
HALMMDKM_01817 5.3e-119 L Transposase
HALMMDKM_01818 2.1e-08 L Transposase
HALMMDKM_01819 1.1e-83 F Belongs to the NrdI family
HALMMDKM_01820 1.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HALMMDKM_01821 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
HALMMDKM_01822 1.5e-65 esbA S Family of unknown function (DUF5322)
HALMMDKM_01823 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HALMMDKM_01824 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HALMMDKM_01825 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
HALMMDKM_01826 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HALMMDKM_01827 1.9e-106 L PFAM Integrase catalytic region
HALMMDKM_01828 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HALMMDKM_01829 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HALMMDKM_01830 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HALMMDKM_01831 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HALMMDKM_01832 4.5e-65 L PFAM transposase IS200-family protein
HALMMDKM_01833 3.1e-69 O Preprotein translocase subunit SecB
HALMMDKM_01835 8.7e-61
HALMMDKM_01836 2e-85 L transposase, IS605 OrfB family
HALMMDKM_01837 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
HALMMDKM_01839 3.6e-17 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
HALMMDKM_01840 6.8e-08 UW Hep Hag repeat protein
HALMMDKM_01841 7.9e-79 O Bacterial dnaA protein
HALMMDKM_01842 5.2e-50
HALMMDKM_01843 0.0 S SEC-C Motif Domain Protein
HALMMDKM_01844 4.5e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01845 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01846 2.5e-129 narI 1.7.5.1 C Nitrate reductase
HALMMDKM_01847 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HALMMDKM_01848 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HALMMDKM_01849 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HALMMDKM_01850 2.6e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HALMMDKM_01851 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HALMMDKM_01852 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HALMMDKM_01853 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HALMMDKM_01854 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HALMMDKM_01855 3e-44
HALMMDKM_01856 1e-190 comP 2.7.13.3 F Sensor histidine kinase
HALMMDKM_01857 2.3e-116 nreC K PFAM regulatory protein LuxR
HALMMDKM_01858 1.6e-18
HALMMDKM_01859 3.6e-182
HALMMDKM_01860 1.4e-164 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HALMMDKM_01861 3.9e-218 narK P Transporter, major facilitator family protein
HALMMDKM_01862 4.9e-35 moaD 2.8.1.12 H ThiS family
HALMMDKM_01863 3.7e-64 moaE 2.8.1.12 H MoaE protein
HALMMDKM_01864 3.3e-77 S Flavodoxin
HALMMDKM_01865 1.2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HALMMDKM_01866 2.3e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HALMMDKM_01867 5e-135 cjaA ET ABC transporter substrate-binding protein
HALMMDKM_01868 3.7e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HALMMDKM_01869 2.1e-96 P ABC transporter permease
HALMMDKM_01870 7.1e-97 papP P ABC transporter, permease protein
HALMMDKM_01871 2.1e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01873 1.1e-54 L Transposase IS66 family
HALMMDKM_01874 4.2e-87 V Type II restriction enzyme, methylase subunits
HALMMDKM_01875 1.4e-139 V Pfam:Methyltransf_26
HALMMDKM_01876 0.0 tetP J Elongation factor G, domain IV
HALMMDKM_01877 3.3e-260 L Transposase
HALMMDKM_01879 3e-24
HALMMDKM_01880 5.1e-173 scrR K Transcriptional regulator, LacI family
HALMMDKM_01881 3.2e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01882 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HALMMDKM_01884 6.5e-90 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_01885 4.6e-111 M repeat protein
HALMMDKM_01886 3.3e-26
HALMMDKM_01887 2.6e-91 S Acyltransferase family
HALMMDKM_01888 4.1e-109 M Glycosyltransferase like family 2
HALMMDKM_01889 5.9e-131 2.4.1.52 GT4 M Glycosyl transferases group 1
HALMMDKM_01890 2.1e-200 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HALMMDKM_01891 2.5e-20 L PFAM transposase IS116 IS110 IS902
HALMMDKM_01892 1.8e-78 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01893 6.1e-125 L PFAM Integrase catalytic region
HALMMDKM_01895 4e-22
HALMMDKM_01896 3.9e-116 L PFAM Integrase catalytic region
HALMMDKM_01898 2.8e-24
HALMMDKM_01899 2.1e-157 spoU 2.1.1.185 J Methyltransferase
HALMMDKM_01900 4.9e-224 oxlT P Major Facilitator Superfamily
HALMMDKM_01901 4e-92 L PFAM Integrase catalytic region
HALMMDKM_01902 7.6e-91 L PFAM Integrase catalytic region
HALMMDKM_01903 5.3e-176 fecB P Periplasmic binding protein
HALMMDKM_01904 8.9e-173
HALMMDKM_01905 1.4e-72
HALMMDKM_01906 1.1e-77 L PFAM Integrase catalytic region
HALMMDKM_01907 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HALMMDKM_01908 1.8e-94 L hmm pf00665
HALMMDKM_01909 5.9e-48 L PFAM transposase IS200-family protein
HALMMDKM_01910 4.6e-131 K LysR substrate binding domain
HALMMDKM_01911 1.4e-104 L Transposase and inactivated derivatives IS30 family
HALMMDKM_01912 6.5e-90 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_01913 1.1e-91
HALMMDKM_01914 9.7e-101 M domain protein
HALMMDKM_01915 1.4e-104 L Transposase and inactivated derivatives IS30 family
HALMMDKM_01916 3.7e-216 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HALMMDKM_01917 1.5e-16 L Integrase core domain
HALMMDKM_01920 1.2e-136 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_01921 3.5e-35
HALMMDKM_01922 1.1e-77 L PFAM Integrase catalytic region
HALMMDKM_01933 1e-90 S Uncharacterised protein family (UPF0236)
HALMMDKM_01934 2.2e-16 K Transcriptional regulator, HxlR family
HALMMDKM_01935 7.9e-79 O Bacterial dnaA protein
HALMMDKM_01936 9.8e-09 K DNA-binding helix-turn-helix protein
HALMMDKM_01937 4.5e-64 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01938 5.5e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01939 2e-35 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_01940 2.7e-70 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01961 4.5e-64 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_01963 5.5e-80 L transposase and inactivated derivatives, IS30 family
HALMMDKM_01966 5.8e-52 S Sugar efflux transporter for intercellular exchange
HALMMDKM_01967 2.7e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HALMMDKM_01968 6.7e-87 L Transposase IS66 family
HALMMDKM_01969 9.8e-42 L Transposase IS66 family
HALMMDKM_01970 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_01971 9.8e-188 L PFAM Integrase catalytic region
HALMMDKM_01972 2.1e-175 L Transposase
HALMMDKM_01973 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_01974 8.3e-221 L Transposase
HALMMDKM_01975 1.4e-259 S Uncharacterised protein family (UPF0236)
HALMMDKM_01982 6.6e-218 L Transposase
HALMMDKM_01983 5.3e-189 L PFAM Integrase catalytic region
HALMMDKM_01984 7.8e-296 L Transposase IS66 family
HALMMDKM_01985 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HALMMDKM_01987 1.2e-120 L Transposase
HALMMDKM_01988 2e-169 L Transposase and inactivated derivatives IS30 family
HALMMDKM_01990 3.6e-260 S Uncharacterised protein family (UPF0236)
HALMMDKM_01991 1.2e-188 L PFAM Integrase catalytic region
HALMMDKM_01992 5.9e-114 L PFAM Integrase catalytic region
HALMMDKM_01993 1.9e-117 L PFAM Integrase catalytic region
HALMMDKM_01994 4.5e-160 L hmm pf00665
HALMMDKM_01995 3.6e-74 L Helix-turn-helix domain
HALMMDKM_01996 2.3e-08 L Helix-turn-helix domain
HALMMDKM_01998 2.4e-52 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HALMMDKM_02000 2.1e-22 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02002 6e-55 L recombinase activity
HALMMDKM_02004 4e-141 L PFAM Integrase catalytic region
HALMMDKM_02005 9.3e-84 L Transposase
HALMMDKM_02006 5.2e-133 L Transposase
HALMMDKM_02007 1.1e-87 L Transposase
HALMMDKM_02008 1.8e-133 L Transposase
HALMMDKM_02009 4.8e-07 cnrT EG EamA-like transporter family
HALMMDKM_02010 2.4e-228 L transposase, IS605 OrfB family
HALMMDKM_02011 2.1e-60 L PFAM transposase IS200-family protein
HALMMDKM_02013 2.6e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_02014 5.8e-52 S Sugar efflux transporter for intercellular exchange
HALMMDKM_02015 3.6e-260 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_02016 2e-169 L Transposase and inactivated derivatives IS30 family
HALMMDKM_02017 1.8e-38 pnb C nitroreductase
HALMMDKM_02018 9.8e-169 L Transposase and inactivated derivatives IS30 family
HALMMDKM_02019 3.3e-139 L hmm pf00665
HALMMDKM_02020 4e-47 L Helix-turn-helix domain
HALMMDKM_02021 1.8e-215 L Integrase core domain
HALMMDKM_02022 1.6e-126 O Bacterial dnaA protein
HALMMDKM_02023 5.9e-48 L PFAM transposase IS200-family protein
HALMMDKM_02024 4e-259 S Uncharacterised protein family (UPF0236)
HALMMDKM_02025 3.3e-85 L PFAM transposase IS200-family protein
HALMMDKM_02026 1.2e-79 L transposase and inactivated derivatives, IS30 family
HALMMDKM_02027 2.4e-66 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_02028 5.1e-139 L Bacterial dnaA protein
HALMMDKM_02029 1.2e-230 L Integrase core domain
HALMMDKM_02031 9.9e-145 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_02032 2.1e-43 lytT K response regulator receiver
HALMMDKM_02034 2.3e-08 L Helix-turn-helix domain
HALMMDKM_02035 6.7e-42 L Helix-turn-helix domain
HALMMDKM_02036 2.4e-77 L Bacterial dnaA protein
HALMMDKM_02037 5e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02038 1.1e-46 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02043 4.4e-27 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_02044 2e-191 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HALMMDKM_02045 2.4e-167 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02046 2e-35 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_02047 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HALMMDKM_02049 1.6e-229 L transposase, IS605 OrfB family
HALMMDKM_02050 2.1e-60 L PFAM transposase IS200-family protein
HALMMDKM_02051 1.1e-64 L PFAM Integrase catalytic region
HALMMDKM_02052 1.1e-115 L PFAM Integrase catalytic region
HALMMDKM_02053 2.8e-93 L PFAM Integrase catalytic region
HALMMDKM_02054 4.4e-64 L PFAM Integrase catalytic region
HALMMDKM_02055 4.7e-216 L Transposase
HALMMDKM_02056 1.5e-140 L PFAM Integrase catalytic region
HALMMDKM_02057 5.2e-113 L Transposase
HALMMDKM_02058 1.4e-87 L Transposase
HALMMDKM_02059 2.2e-168 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02063 3.9e-122 L hmm pf00665
HALMMDKM_02064 2.4e-76 L Helix-turn-helix domain
HALMMDKM_02065 1.7e-103 O Bacterial dnaA protein
HALMMDKM_02066 4.4e-192 L Integrase core domain
HALMMDKM_02067 1e-198 S Uncharacterised protein family (UPF0236)
HALMMDKM_02069 7.8e-16 G Belongs to the glycosyl hydrolase family 6
HALMMDKM_02070 1.1e-91 tra L Transposase and inactivated derivatives, IS30 family
HALMMDKM_02071 1.6e-32 ppaC 3.6.1.1 C inorganic pyrophosphatase
HALMMDKM_02072 8.8e-262 L PFAM Integrase catalytic region
HALMMDKM_02075 1.1e-64 L PFAM Integrase catalytic region
HALMMDKM_02076 2.2e-116 L PFAM Integrase catalytic region
HALMMDKM_02077 5.5e-55 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HALMMDKM_02078 6.7e-78 L transposase and inactivated derivatives, IS30 family
HALMMDKM_02079 6.4e-14 L PFAM transposase IS116 IS110 IS902
HALMMDKM_02080 3.4e-177 L PFAM Integrase catalytic region
HALMMDKM_02081 1.2e-190 L PFAM Integrase catalytic region
HALMMDKM_02082 1.2e-180 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HALMMDKM_02083 6.2e-190 L PFAM Integrase catalytic region
HALMMDKM_02084 2e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02085 4.5e-65 L PFAM transposase IS200-family protein
HALMMDKM_02086 7.5e-153 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HALMMDKM_02087 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HALMMDKM_02088 3.3e-55 S Sugar efflux transporter for intercellular exchange
HALMMDKM_02089 6e-205 L Transposase
HALMMDKM_02090 7.5e-188 L PFAM Integrase catalytic region
HALMMDKM_02091 6.8e-170 L Transposase and inactivated derivatives IS30 family
HALMMDKM_02092 1.1e-64 L PFAM Integrase catalytic region
HALMMDKM_02093 1.1e-115 L PFAM Integrase catalytic region
HALMMDKM_02094 5.4e-11 L Transposase IS66 family
HALMMDKM_02095 2e-188 L PFAM Integrase catalytic region
HALMMDKM_02096 1.4e-38 L PFAM Integrase catalytic region
HALMMDKM_02097 9.8e-53 L PFAM Integrase catalytic region
HALMMDKM_02098 2.1e-08 L Transposase
HALMMDKM_02099 9.5e-183 L PFAM Integrase catalytic region
HALMMDKM_02100 9.6e-61 L PFAM transposase IS200-family protein
HALMMDKM_02101 1.5e-23

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)