ORF_ID e_value Gene_name EC_number CAZy COGs Description
MMHHMPGL_00001 3.2e-150 cglB NU type II secretion system
MMHHMPGL_00002 7.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MMHHMPGL_00003 1.1e-161 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MMHHMPGL_00004 1e-81 yffB K Transcriptional regulator
MMHHMPGL_00005 1.1e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MMHHMPGL_00006 3.8e-68 S cog cog4699
MMHHMPGL_00007 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMHHMPGL_00008 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMHHMPGL_00009 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MMHHMPGL_00010 2.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MMHHMPGL_00011 2.7e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MMHHMPGL_00012 2.9e-76 ilvN 2.2.1.6 E Acetolactate synthase
MMHHMPGL_00013 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MMHHMPGL_00014 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MMHHMPGL_00015 3.2e-303 yloV S kinase related to dihydroxyacetone kinase
MMHHMPGL_00016 1.8e-57 asp S cog cog1302
MMHHMPGL_00017 2.1e-222 norN V Mate efflux family protein
MMHHMPGL_00018 1.3e-276 thrC 4.2.3.1 E Threonine synthase
MMHHMPGL_00021 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MMHHMPGL_00022 0.0 pepO 3.4.24.71 O Peptidase family M13
MMHHMPGL_00023 4e-52 dexB 2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97 GH101,GH13,GH29,GH31 G hydrolase activity, hydrolyzing O-glycosyl compounds
MMHHMPGL_00024 4.3e-124 treR K trehalose operon
MMHHMPGL_00025 1.5e-95 ywlG S Belongs to the UPF0340 family
MMHHMPGL_00028 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
MMHHMPGL_00030 8.4e-251 6.3.2.2 H gamma-glutamylcysteine synthetase
MMHHMPGL_00031 4.4e-62 rplQ J ribosomal protein l17
MMHHMPGL_00032 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMHHMPGL_00033 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MMHHMPGL_00034 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MMHHMPGL_00035 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MMHHMPGL_00036 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MMHHMPGL_00037 5.6e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MMHHMPGL_00038 8.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MMHHMPGL_00039 9.7e-58 rplO J binds to the 23S rRNA
MMHHMPGL_00040 1.9e-23 rpmD J ribosomal protein l30
MMHHMPGL_00041 7.7e-80 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MMHHMPGL_00042 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MMHHMPGL_00043 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MMHHMPGL_00044 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MMHHMPGL_00045 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMHHMPGL_00046 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MMHHMPGL_00047 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MMHHMPGL_00048 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MMHHMPGL_00049 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MMHHMPGL_00050 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MMHHMPGL_00051 4.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MMHHMPGL_00052 2.8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MMHHMPGL_00053 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MMHHMPGL_00054 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MMHHMPGL_00055 1.2e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MMHHMPGL_00056 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MMHHMPGL_00057 1.3e-103 rplD J Forms part of the polypeptide exit tunnel
MMHHMPGL_00058 1.6e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MMHHMPGL_00059 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MMHHMPGL_00060 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MMHHMPGL_00061 0.0 XK27_09800 I Acyltransferase
MMHHMPGL_00062 3.6e-25 XK27_09805 S regulation of ryanodine-sensitive calcium-release channel activity
MMHHMPGL_00063 1.5e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMHHMPGL_00064 7.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MMHHMPGL_00065 4.1e-92 adk 2.7.4.3 F topology modulation protein
MMHHMPGL_00066 1e-96 S Domain of unknown function (DUF1851)
MMHHMPGL_00067 1.3e-142 2.3.1.81 V aminoglycoside
MMHHMPGL_00068 2.3e-22 K Transcriptional regulator
MMHHMPGL_00069 9.7e-208 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MMHHMPGL_00070 1.4e-237 stp_1 EGP Major facilitator Superfamily
MMHHMPGL_00071 2.1e-88 K TRANSCRIPTIONal
MMHHMPGL_00073 1.6e-158 L Replication initiation factor
MMHHMPGL_00074 1.9e-18 S Domain of unknown function (DUF3173)
MMHHMPGL_00075 1.6e-213 int L Belongs to the 'phage' integrase family
MMHHMPGL_00077 9.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MMHHMPGL_00078 1.9e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MMHHMPGL_00079 6.3e-44 yrzL S Belongs to the UPF0297 family
MMHHMPGL_00080 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MMHHMPGL_00081 3.2e-44 yrzB S Belongs to the UPF0473 family
MMHHMPGL_00082 3.6e-283 ccs S the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_00083 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MMHHMPGL_00084 2.6e-14
MMHHMPGL_00085 8.4e-90 XK27_10930 K acetyltransferase
MMHHMPGL_00086 4.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MMHHMPGL_00087 2.7e-129 yaaA S Belongs to the UPF0246 family
MMHHMPGL_00088 7.6e-169 XK27_01785 S cog cog1284
MMHHMPGL_00089 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MMHHMPGL_00091 1.3e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
MMHHMPGL_00092 3.6e-218 metE 2.1.1.14 E Methionine synthase
MMHHMPGL_00093 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MMHHMPGL_00094 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MMHHMPGL_00095 4.4e-55 K HxlR-like helix-turn-helix
MMHHMPGL_00096 9.7e-11 S Pseudomonas avirulence D protein (AvrD)
MMHHMPGL_00098 3.4e-220 mmr P Major Facilitator Superfamily
MMHHMPGL_00100 1.9e-07
MMHHMPGL_00105 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMHHMPGL_00106 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MMHHMPGL_00107 4.6e-35 XK27_02060 S Transglycosylase associated protein
MMHHMPGL_00108 3e-72 badR K Transcriptional regulator, marr family
MMHHMPGL_00110 2e-283 ahpF O alkyl hydroperoxide reductase
MMHHMPGL_00111 9.3e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
MMHHMPGL_00112 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
MMHHMPGL_00113 3.5e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MMHHMPGL_00114 4.2e-83 S Putative small multi-drug export protein
MMHHMPGL_00115 8.2e-76 ctsR K Belongs to the CtsR family
MMHHMPGL_00116 0.0 clpC O Belongs to the ClpA ClpB family
MMHHMPGL_00117 2.1e-214 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MMHHMPGL_00118 1.7e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MMHHMPGL_00119 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MMHHMPGL_00120 3.8e-142 S SseB protein N-terminal domain
MMHHMPGL_00121 9e-110 cysE 2.3.1.30 E serine acetyltransferase
MMHHMPGL_00123 3.6e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMHHMPGL_00124 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MMHHMPGL_00126 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMHHMPGL_00127 5.4e-92 yacP S RNA-binding protein containing a PIN domain
MMHHMPGL_00128 5.5e-150 degV S DegV family
MMHHMPGL_00130 5.1e-22 K Transcriptional
MMHHMPGL_00131 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MMHHMPGL_00132 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MMHHMPGL_00133 1.5e-55 int2 L Belongs to the 'phage' integrase family
MMHHMPGL_00134 2.1e-141 int2 L Belongs to the 'phage' integrase family
MMHHMPGL_00135 1.1e-40 S Helix-turn-helix domain
MMHHMPGL_00136 1.9e-189 L Replication initiation factor
MMHHMPGL_00137 6.9e-37
MMHHMPGL_00139 8.1e-81 K DNA-binding helix-turn-helix protein
MMHHMPGL_00141 9.9e-242 salB V Lanthionine synthetase C-like protein
MMHHMPGL_00142 4e-257 salB V Lanthionine synthetase C-like protein
MMHHMPGL_00143 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMHHMPGL_00144 4.2e-122 V ABC transporter
MMHHMPGL_00145 6.7e-289 V FtsX-like permease family
MMHHMPGL_00146 6.6e-234 salK 2.7.13.3 T Histidine kinase
MMHHMPGL_00147 4.7e-103 salR K helix_turn_helix, Lux Regulon
MMHHMPGL_00149 4.7e-17 S Toxin-antitoxin system, toxin component, RelE family
MMHHMPGL_00150 4.9e-17
MMHHMPGL_00151 5.3e-30 K Helix-turn-helix domain
MMHHMPGL_00153 9.5e-155 srtB 3.4.22.70 S Sortase family
MMHHMPGL_00154 1.2e-227 capA M Bacterial capsule synthesis protein
MMHHMPGL_00155 3.6e-39 gcvR T UPF0237 protein
MMHHMPGL_00156 1.7e-243 XK27_08635 S UPF0210 protein
MMHHMPGL_00157 6.6e-133 ais G Phosphoglycerate mutase
MMHHMPGL_00158 5.5e-136 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MMHHMPGL_00159 3.2e-13 acmA 3.2.1.17 NU Muramidase (Flagellum-specific)
MMHHMPGL_00160 1.2e-80 acmA 3.2.1.17 NU Muramidase (Flagellum-specific)
MMHHMPGL_00161 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MMHHMPGL_00162 3.3e-65 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MMHHMPGL_00164 3.2e-304 dnaK O Heat shock 70 kDa protein
MMHHMPGL_00165 9.1e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MMHHMPGL_00166 4.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MMHHMPGL_00167 6.9e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MMHHMPGL_00168 3.3e-80 hmpT S cog cog4720
MMHHMPGL_00169 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MMHHMPGL_00170 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MMHHMPGL_00171 3e-237 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MMHHMPGL_00172 7.6e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MMHHMPGL_00174 1.3e-60 divIC D Septum formation initiator
MMHHMPGL_00175 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MMHHMPGL_00176 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MMHHMPGL_00177 1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MMHHMPGL_00178 1.5e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MMHHMPGL_00179 4.9e-30 yyzM S Protein conserved in bacteria
MMHHMPGL_00180 1.6e-200 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MMHHMPGL_00181 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MMHHMPGL_00182 2.1e-132 parB K Belongs to the ParB family
MMHHMPGL_00183 1.2e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MMHHMPGL_00184 3.1e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MMHHMPGL_00185 2.1e-120 yoaK S Protein of unknown function (DUF1275)
MMHHMPGL_00189 0.0 XK27_10405 S Bacterial membrane protein YfhO
MMHHMPGL_00190 3.3e-305 ybiT S abc transporter atp-binding protein
MMHHMPGL_00191 4.9e-154 yvjA S membrane
MMHHMPGL_00192 1.5e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MMHHMPGL_00193 3.6e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MMHHMPGL_00194 3.6e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MMHHMPGL_00195 2.1e-48 yaaA S S4 domain
MMHHMPGL_00196 1.7e-232 ymfF S Peptidase M16
MMHHMPGL_00197 3.8e-240 ymfH S Peptidase M16
MMHHMPGL_00198 5e-143 ymfM S sequence-specific DNA binding
MMHHMPGL_00199 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MMHHMPGL_00200 1.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMHHMPGL_00201 1.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMHHMPGL_00202 4.2e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMHHMPGL_00203 1.6e-68 lytE M LysM domain protein
MMHHMPGL_00204 3.6e-59 isaA GH23 M Immunodominant staphylococcal antigen A
MMHHMPGL_00205 0.0 S Bacterial membrane protein, YfhO
MMHHMPGL_00206 4e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MMHHMPGL_00207 1.3e-97 yvbG U UPF0056 membrane protein
MMHHMPGL_00208 4.2e-80 F NUDIX domain
MMHHMPGL_00209 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MMHHMPGL_00210 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MMHHMPGL_00211 5.3e-75 rplI J binds to the 23S rRNA
MMHHMPGL_00212 4.2e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MMHHMPGL_00213 1.8e-47 veg S Biofilm formation stimulator VEG
MMHHMPGL_00214 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MMHHMPGL_00215 6.5e-11
MMHHMPGL_00216 2e-53 ypaA M Membrane
MMHHMPGL_00217 9.9e-97 XK27_06935 K transcriptional regulator
MMHHMPGL_00218 3.9e-161 XK27_06930 V domain protein
MMHHMPGL_00219 6e-117 S Putative adhesin
MMHHMPGL_00220 6e-63 XK27_06920 S Protein of unknown function (DUF1700)
MMHHMPGL_00221 9.1e-53 K transcriptional regulator, PadR family
MMHHMPGL_00222 1.5e-104 nudL L hydrolase
MMHHMPGL_00223 1.7e-54 bta 1.8.1.8 CO transport accessory protein
MMHHMPGL_00224 2.6e-73 L thioesterase
MMHHMPGL_00225 6e-143 S Macro domain protein
MMHHMPGL_00226 1.7e-51 trxA O Belongs to the thioredoxin family
MMHHMPGL_00227 1.2e-73 yccU S CoA-binding protein
MMHHMPGL_00228 2.2e-145 tatD L Hydrolase, tatd
MMHHMPGL_00229 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MMHHMPGL_00230 3.8e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MMHHMPGL_00232 8.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MMHHMPGL_00233 1.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MMHHMPGL_00234 1.7e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
MMHHMPGL_00235 3.8e-171 rmuC S RmuC domain protein
MMHHMPGL_00236 7.6e-177 cbf S 3'-5' exoribonuclease yhaM
MMHHMPGL_00237 4.5e-141 purR 2.4.2.7 F operon repressor
MMHHMPGL_00238 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MMHHMPGL_00239 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MMHHMPGL_00240 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MMHHMPGL_00241 1.3e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MMHHMPGL_00242 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MMHHMPGL_00243 2.8e-85 S Fusaric acid resistance protein-like
MMHHMPGL_00244 1.6e-61 glnR K Transcriptional regulator
MMHHMPGL_00245 3.2e-261 glnA 6.3.1.2 E glutamine synthetase
MMHHMPGL_00246 2.3e-92 pscB M CHAP domain protein
MMHHMPGL_00247 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMHHMPGL_00248 2.4e-31 ykzG S Belongs to the UPF0356 family
MMHHMPGL_00249 1.3e-109 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MMHHMPGL_00250 1.1e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MMHHMPGL_00251 4.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MMHHMPGL_00252 6.7e-114 azlC E AzlC protein
MMHHMPGL_00253 1.5e-47 azlD S branched-chain amino acid
MMHHMPGL_00254 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MMHHMPGL_00255 1.3e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MMHHMPGL_00256 8.3e-157 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMHHMPGL_00257 1.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MMHHMPGL_00258 3.9e-93 cvpA S toxin biosynthetic process
MMHHMPGL_00259 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MMHHMPGL_00260 1.3e-230 lanM V Domain of unknown function (DUF4135)
MMHHMPGL_00261 3.1e-194 3.6.3.27 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMHHMPGL_00262 5.2e-10
MMHHMPGL_00263 6e-129 V ABC transporter, ATP-binding protein
MMHHMPGL_00264 1.8e-223 V ABC transporter (Permease
MMHHMPGL_00265 3.1e-18 L Integrase core domain protein
MMHHMPGL_00266 5.5e-15
MMHHMPGL_00268 0.0 V ABC transporter (Permease
MMHHMPGL_00269 3.4e-228 2.7.13.3 T Histidine kinase
MMHHMPGL_00270 1.1e-93 salR K helix_turn_helix, Lux Regulon
MMHHMPGL_00271 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMHHMPGL_00273 8.3e-51 CP_0034 A G5
MMHHMPGL_00281 2.6e-10
MMHHMPGL_00287 2.5e-131 mreC M Involved in formation and maintenance of cell shape
MMHHMPGL_00288 2e-78 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MMHHMPGL_00289 1.4e-89 usp 3.5.1.28 CBM50 S CHAP domain
MMHHMPGL_00290 1.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMHHMPGL_00291 9.4e-217 araT 2.6.1.1 E Aminotransferase
MMHHMPGL_00292 2.2e-142 recO L Involved in DNA repair and RecF pathway recombination
MMHHMPGL_00293 3e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MMHHMPGL_00294 9.9e-36 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMHHMPGL_00295 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MMHHMPGL_00296 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMHHMPGL_00297 2.6e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MMHHMPGL_00298 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MMHHMPGL_00299 1.7e-96 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MMHHMPGL_00300 1.2e-291 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MMHHMPGL_00301 1.5e-160 S CHAP domain
MMHHMPGL_00302 2.3e-237 purD 6.3.4.13 F Belongs to the GARS family
MMHHMPGL_00303 3.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MMHHMPGL_00304 1.9e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MMHHMPGL_00305 1.5e-172 1.1.1.169 H Ketopantoate reductase
MMHHMPGL_00306 8.6e-34
MMHHMPGL_00307 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MMHHMPGL_00308 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MMHHMPGL_00309 4.9e-210 sip L Belongs to the 'phage' integrase family
MMHHMPGL_00310 6.5e-36 xre K Cro/C1-type HTH DNA-binding domain
MMHHMPGL_00311 2.1e-20 K TRANSCRIPTIONal
MMHHMPGL_00315 6.1e-14
MMHHMPGL_00316 5.3e-22
MMHHMPGL_00317 4.5e-136 KL Phage plasmid primase P4 family
MMHHMPGL_00318 1.2e-240 S DNA primase
MMHHMPGL_00320 1.8e-11
MMHHMPGL_00322 7.3e-32 gepA K Phage-associated protein
MMHHMPGL_00324 1.1e-69 argR K Regulates arginine biosynthesis genes
MMHHMPGL_00325 5.1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MMHHMPGL_00326 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MMHHMPGL_00327 3.5e-71 S Protein of unknown function (DUF3021)
MMHHMPGL_00328 4.2e-69 K LytTr DNA-binding domain
MMHHMPGL_00330 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MMHHMPGL_00332 5.9e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MMHHMPGL_00333 8.6e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MMHHMPGL_00334 6.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
MMHHMPGL_00335 1.4e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MMHHMPGL_00336 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MMHHMPGL_00337 4.1e-82 L Transposase
MMHHMPGL_00338 1.5e-63 gpm 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
MMHHMPGL_00342 1.9e-41
MMHHMPGL_00343 1.3e-37 L Transposase IS116 IS110 IS902
MMHHMPGL_00344 6e-78 L transposase IS116 IS110 IS902 family
MMHHMPGL_00347 9.1e-22 XK27_10050 K Peptidase S24-like
MMHHMPGL_00348 3.3e-91
MMHHMPGL_00349 1.1e-84 cbiO V ABC transporter
MMHHMPGL_00354 3.4e-85 I radical SAM domain protein
MMHHMPGL_00355 2.1e-07 S Bacteriocin subtilosin A
MMHHMPGL_00356 1.7e-82 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MMHHMPGL_00357 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
MMHHMPGL_00358 7.2e-15
MMHHMPGL_00360 1.6e-54 S PcfJ-like protein
MMHHMPGL_00361 2.5e-10 S PcfK-like protein
MMHHMPGL_00362 1.1e-38 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MMHHMPGL_00364 1.5e-17
MMHHMPGL_00365 9.1e-75 S Region found in RelA / SpoT proteins
MMHHMPGL_00366 1.3e-28 dnaG L DNA primase activity
MMHHMPGL_00367 3.1e-25 soj D ATPases involved in chromosome partitioning
MMHHMPGL_00369 4.7e-08 L Psort location Cytoplasmic, score 8.96
MMHHMPGL_00370 1.6e-20 xerS L Belongs to the 'phage' integrase family
MMHHMPGL_00371 8.7e-53 spd F DNA RNA non-specific endonuclease
MMHHMPGL_00373 1.5e-91 qorB 1.6.5.2 GM NmrA family
MMHHMPGL_00374 6.1e-25
MMHHMPGL_00375 1.4e-59 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MMHHMPGL_00376 3.5e-09 S SnoaL-like domain
MMHHMPGL_00377 1e-44 S SnoaL-like domain
MMHHMPGL_00378 1.6e-33 S Immunity protein 41
MMHHMPGL_00379 9e-08 S Enterocin A Immunity
MMHHMPGL_00380 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MMHHMPGL_00381 6.5e-266 S dextransucrase activity
MMHHMPGL_00382 0.0 S dextransucrase activity
MMHHMPGL_00383 6.6e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MMHHMPGL_00384 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MMHHMPGL_00385 8.1e-310 S dextransucrase activity
MMHHMPGL_00387 1.6e-124 XK27_00785 S CAAX protease self-immunity
MMHHMPGL_00388 5.3e-243 EGP Major facilitator Superfamily
MMHHMPGL_00389 1.5e-65 rmaI K DNA-binding transcription factor activity
MMHHMPGL_00390 2e-95 maa 2.3.1.79 GK Maltose O-acetyltransferase
MMHHMPGL_00391 2.8e-129 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
MMHHMPGL_00392 3e-229 vraA 6.2.1.3 IQ AMP-binding enzyme
MMHHMPGL_00393 3.1e-206 vraB 2.3.1.9 I Belongs to the thiolase family
MMHHMPGL_00394 5.8e-86
MMHHMPGL_00395 0.0 3.5.1.28 GM domain, Protein
MMHHMPGL_00396 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MMHHMPGL_00397 2.1e-20
MMHHMPGL_00398 1.6e-140 S haloacid dehalogenase-like hydrolase
MMHHMPGL_00399 2.2e-08 3.2.1.51 GH95 U LPXTG cell wall anchor motif
MMHHMPGL_00400 1.2e-122 fhaB M Rib/alpha-like repeat
MMHHMPGL_00401 0.0 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
MMHHMPGL_00402 0.0 GM domain, Protein
MMHHMPGL_00403 1.5e-214 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MMHHMPGL_00404 0.0 sbcC L ATPase involved in DNA repair
MMHHMPGL_00405 0.0 M family 8
MMHHMPGL_00406 1.2e-219 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MMHHMPGL_00407 1.4e-305 asp1 S Accessory Sec system protein Asp1
MMHHMPGL_00408 1.9e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
MMHHMPGL_00409 5.4e-80 asp3 S Accessory Sec system protein Asp3
MMHHMPGL_00410 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MMHHMPGL_00411 2.3e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MMHHMPGL_00412 2.5e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MMHHMPGL_00413 2.6e-17 S Accessory secretory protein Sec Asp4
MMHHMPGL_00414 4.7e-16 S Accessory secretory protein Sec, Asp5
MMHHMPGL_00415 1.7e-190 nss M transferase activity, transferring glycosyl groups
MMHHMPGL_00417 2.2e-10
MMHHMPGL_00419 1.8e-18
MMHHMPGL_00420 3.7e-79 S peptidoglycan catabolic process
MMHHMPGL_00421 1.5e-22 S COG5546 Small integral membrane protein
MMHHMPGL_00422 6.5e-54 S Pfam:Phage_holin_4_1
MMHHMPGL_00423 2.2e-21
MMHHMPGL_00424 1.3e-167 S peptidoglycan catabolic process
MMHHMPGL_00425 6.4e-107
MMHHMPGL_00426 2.9e-205 S transmembrane transport
MMHHMPGL_00427 5.1e-95 S Bacteriophage Gp15 protein
MMHHMPGL_00428 2.5e-27
MMHHMPGL_00429 1.3e-70
MMHHMPGL_00430 1.2e-65 S Minor capsid protein from bacteriophage
MMHHMPGL_00431 5.9e-22 S Minor capsid protein
MMHHMPGL_00432 6.5e-22 S Minor capsid protein
MMHHMPGL_00433 2.3e-55
MMHHMPGL_00435 1.5e-144 S peptidase activity
MMHHMPGL_00436 6.9e-70 S Phage minor structural protein GP20
MMHHMPGL_00437 1.5e-126 M Phage minor capsid protein 2
MMHHMPGL_00438 1.1e-259 S Phage portal protein, SPP1 Gp6-like
MMHHMPGL_00439 6.7e-224 S Pfam:Terminase_3C
MMHHMPGL_00440 3.6e-46 L DNA packaging
MMHHMPGL_00441 2.8e-36 arpU S Transcriptional regulator, ArpU family
MMHHMPGL_00443 3.5e-11 S YopX protein
MMHHMPGL_00445 9.7e-144 S C-5 cytosine-specific DNA methylase
MMHHMPGL_00446 5.2e-71 S sequence-specific DNA binding
MMHHMPGL_00448 2.2e-07 S Protein of unknown function (DUF1642)
MMHHMPGL_00451 2.8e-71 S magnesium ion binding
MMHHMPGL_00452 3.5e-64 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MMHHMPGL_00453 2.5e-45 S Protein of unknown function (DUF1351)
MMHHMPGL_00454 3.2e-31 S ERF superfamily
MMHHMPGL_00456 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_00457 1.1e-17 S Domain of unknown function (DUF4649)
MMHHMPGL_00458 1.4e-176 XK27_08835 S ABC transporter substrate binding protein
MMHHMPGL_00459 9.9e-139 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MMHHMPGL_00460 9.9e-135 XK27_08845 S abc transporter atp-binding protein
MMHHMPGL_00461 9.2e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMHHMPGL_00462 1.6e-151 estA CE1 S Putative esterase
MMHHMPGL_00463 5.7e-124 XK27_08875 O Zinc-dependent metalloprotease
MMHHMPGL_00464 5.7e-19 XK27_08880
MMHHMPGL_00465 1e-75 fld C Flavodoxin
MMHHMPGL_00466 1.7e-279 clcA P Chloride transporter, ClC family
MMHHMPGL_00467 2.2e-36 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MMHHMPGL_00468 6.8e-218 XK27_05110 P Chloride transporter ClC family
MMHHMPGL_00469 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MMHHMPGL_00472 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
MMHHMPGL_00473 1.9e-161 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MMHHMPGL_00474 3.8e-85 ytsP 1.8.4.14 T GAF domain-containing protein
MMHHMPGL_00475 3e-293 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMHHMPGL_00476 9.3e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MMHHMPGL_00477 2.9e-205 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MMHHMPGL_00478 2.3e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MMHHMPGL_00479 1e-134
MMHHMPGL_00481 1.5e-247 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
MMHHMPGL_00482 2.8e-194 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MMHHMPGL_00483 9.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMHHMPGL_00484 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
MMHHMPGL_00485 2.5e-158 endA F DNA RNA non-specific endonuclease
MMHHMPGL_00486 8e-61 T Ser Thr phosphatase family protein
MMHHMPGL_00487 7.9e-222 thrE S membrane
MMHHMPGL_00488 5.9e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
MMHHMPGL_00489 4.8e-97 dhaL 2.7.1.121 S Dihydroxyacetone kinase
MMHHMPGL_00490 5.2e-60 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
MMHHMPGL_00491 7.7e-180 XK27_10475 S oxidoreductase
MMHHMPGL_00493 1.9e-278 XK27_07020 S Belongs to the UPF0371 family
MMHHMPGL_00494 1e-156 msmR K AraC family transcriptional regulator
MMHHMPGL_00495 0.0 rafA 3.2.1.22 G alpha-galactosidase
MMHHMPGL_00496 2e-196 msmE G Bacterial extracellular solute-binding protein
MMHHMPGL_00497 2.7e-144 msmF P Binding-protein-dependent transport system inner membrane component
MMHHMPGL_00498 1.3e-143 msmG P ABC-type sugar transport system, permease component
MMHHMPGL_00499 3.6e-189 msmX P Belongs to the ABC transporter superfamily
MMHHMPGL_00500 2.2e-96 iolC 2.7.1.4 G pfkB family carbohydrate kinase
MMHHMPGL_00501 3.3e-195 gtfA 2.4.1.329, 2.4.1.7 GH13 G Alpha amylase, catalytic domain
MMHHMPGL_00502 2.2e-301 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
MMHHMPGL_00503 2.4e-181 galR K Transcriptional regulator
MMHHMPGL_00504 2.5e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MMHHMPGL_00505 3.4e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MMHHMPGL_00506 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MMHHMPGL_00507 2e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MMHHMPGL_00508 0.0 lacS G transporter
MMHHMPGL_00509 0.0 lacL 3.2.1.23 G -beta-galactosidase
MMHHMPGL_00510 4.6e-208 S Tetratricopeptide repeat
MMHHMPGL_00511 3.5e-157 yvgN C reductase
MMHHMPGL_00512 4.2e-30 XK27_10490
MMHHMPGL_00513 2.9e-38 DJ nuclease activity
MMHHMPGL_00514 6.9e-103 yoaK S Protein of unknown function (DUF1275)
MMHHMPGL_00515 4.6e-109 drgA C Nitroreductase family
MMHHMPGL_00516 6.9e-127 T Transcriptional regulatory protein, C terminal
MMHHMPGL_00517 3.8e-146 T PhoQ Sensor
MMHHMPGL_00518 4.9e-126 S ABC-2 family transporter protein
MMHHMPGL_00519 1e-165 bcrA V abc transporter atp-binding protein
MMHHMPGL_00520 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMHHMPGL_00521 8e-157 E Alpha/beta hydrolase of unknown function (DUF915)
MMHHMPGL_00522 8.9e-75 ywnA K Transcriptional regulator
MMHHMPGL_00523 1.8e-148 1.13.11.2 S glyoxalase
MMHHMPGL_00524 5.3e-107 XK27_02070 S nitroreductase
MMHHMPGL_00525 6.1e-171 ydhF S Aldo keto reductase
MMHHMPGL_00526 2e-42 S Sugar efflux transporter for intercellular exchange
MMHHMPGL_00527 5.4e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MMHHMPGL_00528 0.0 S dextransucrase activity
MMHHMPGL_00529 7.9e-223 yfnA E amino acid
MMHHMPGL_00530 1.2e-50 XK27_01300 S ASCH
MMHHMPGL_00531 9.8e-108 S Carbohydrate-binding domain-containing protein Cthe_2159
MMHHMPGL_00532 2.8e-17 csbD K CsbD-like
MMHHMPGL_00533 2.8e-106 S Protein of unknown function (DUF421)
MMHHMPGL_00534 1.8e-59 S Protein of unknown function (DUF3290)
MMHHMPGL_00535 9.3e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
MMHHMPGL_00536 9.9e-231 brnQ E Component of the transport system for branched-chain amino acids
MMHHMPGL_00537 1.6e-182 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMHHMPGL_00539 2e-231 norM V Multidrug efflux pump
MMHHMPGL_00540 2.2e-219 pbuX F xanthine permease
MMHHMPGL_00541 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MMHHMPGL_00542 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MMHHMPGL_00543 1.2e-161 T Histidine kinase
MMHHMPGL_00544 2.3e-131 macB2 V ABC transporter, ATP-binding protein
MMHHMPGL_00545 0.0 V ABC transporter (permease)
MMHHMPGL_00546 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
MMHHMPGL_00547 4.4e-30 liaI KT membrane
MMHHMPGL_00549 3e-159 XK27_09825 V 'abc transporter, ATP-binding protein
MMHHMPGL_00550 7.6e-132 yvfS V ABC-2 type transporter
MMHHMPGL_00551 4.3e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
MMHHMPGL_00552 1.9e-164 yocS S Transporter
MMHHMPGL_00553 0.0 hscC O Belongs to the heat shock protein 70 family
MMHHMPGL_00554 5.2e-235 anK3 G response to abiotic stimulus
MMHHMPGL_00558 5.6e-158 XK27_09825 V abc transporter atp-binding protein
MMHHMPGL_00559 2.6e-132 yvfS V ABC-2 type transporter
MMHHMPGL_00560 2.9e-180 desK 2.7.13.3 T Histidine kinase
MMHHMPGL_00561 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MMHHMPGL_00562 1.9e-81
MMHHMPGL_00564 1.8e-87
MMHHMPGL_00565 3.2e-47
MMHHMPGL_00566 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
MMHHMPGL_00567 2.2e-122 sdaAB 4.3.1.17 E L-serine dehydratase
MMHHMPGL_00568 1.2e-138 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H phosphomethylpyrimidine kinase
MMHHMPGL_00569 1.2e-104 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MMHHMPGL_00570 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MMHHMPGL_00571 1.6e-83 thiW S Thiamine-precursor transporter protein (ThiW)
MMHHMPGL_00572 4.2e-124 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MMHHMPGL_00573 1.1e-105 P cobalt transport
MMHHMPGL_00574 1.5e-250 P abc transporter atp-binding protein
MMHHMPGL_00575 3.6e-89 S ABC-type cobalt transport system, permease component
MMHHMPGL_00576 5.3e-66 bioY S biotin transmembrane transporter activity
MMHHMPGL_00577 2.4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MMHHMPGL_00578 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MMHHMPGL_00579 2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMHHMPGL_00580 3.2e-92 pat 2.3.1.183 M acetyltransferase
MMHHMPGL_00581 1.5e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMHHMPGL_00583 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MMHHMPGL_00584 3.5e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MMHHMPGL_00585 4.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MMHHMPGL_00586 0.0 smc D Required for chromosome condensation and partitioning
MMHHMPGL_00587 2.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MMHHMPGL_00588 3.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MMHHMPGL_00589 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMHHMPGL_00591 9.1e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MMHHMPGL_00592 1.6e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MMHHMPGL_00594 8.2e-85 S ECF-type riboflavin transporter, S component
MMHHMPGL_00595 5.5e-158 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MMHHMPGL_00596 1.5e-84 XK27_01265 S ECF-type riboflavin transporter, S component
MMHHMPGL_00597 1.2e-293 yfmM S abc transporter atp-binding protein
MMHHMPGL_00598 9.2e-256 noxE P NADH oxidase
MMHHMPGL_00599 2.4e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MMHHMPGL_00600 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMHHMPGL_00601 4.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MMHHMPGL_00602 2.3e-66 yaeR E COG0346 Lactoylglutathione lyase and related lyases
MMHHMPGL_00603 8.4e-163 ypuA S secreted protein
MMHHMPGL_00604 4.9e-71 mntH P Mn2 and Fe2 transporters of the NRAMP family
MMHHMPGL_00605 9.4e-136 mntH P Mn2 and Fe2 transporters of the NRAMP family
MMHHMPGL_00606 4.8e-44 rpmE2 J 50S ribosomal protein L31
MMHHMPGL_00607 2.7e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MMHHMPGL_00608 1.3e-168 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MMHHMPGL_00609 2.6e-154 gst O Glutathione S-transferase
MMHHMPGL_00610 2.8e-185 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MMHHMPGL_00611 4.2e-112 tdk 2.7.1.21 F thymidine kinase
MMHHMPGL_00612 7.1e-187 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MMHHMPGL_00613 2.1e-130 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MMHHMPGL_00614 4.1e-107 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MMHHMPGL_00615 4.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MMHHMPGL_00616 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MMHHMPGL_00617 2.1e-100 pvaA M lytic transglycosylase activity
MMHHMPGL_00618 0.0 yfiB1 V abc transporter atp-binding protein
MMHHMPGL_00619 7.3e-311 XK27_10035 V abc transporter atp-binding protein
MMHHMPGL_00620 4.2e-09 S D-Ala-teichoic acid biosynthesis protein
MMHHMPGL_00621 2.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMHHMPGL_00622 1.9e-236 dltB M Membrane protein involved in D-alanine export
MMHHMPGL_00623 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMHHMPGL_00624 3.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MMHHMPGL_00625 0.0 3.6.3.8 P cation transport ATPase
MMHHMPGL_00626 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MMHHMPGL_00628 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MMHHMPGL_00629 1.5e-163 metF 1.5.1.20 E reductase
MMHHMPGL_00630 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MMHHMPGL_00631 8.5e-91 panT S Pfam:DUF3816
MMHHMPGL_00632 2.4e-93 panT S ECF transporter, substrate-specific component
MMHHMPGL_00633 1.8e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MMHHMPGL_00634 1.3e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MMHHMPGL_00635 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MMHHMPGL_00636 6.8e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MMHHMPGL_00637 1.5e-229 T PhoQ Sensor
MMHHMPGL_00638 4.6e-30 rpsT J Binds directly to 16S ribosomal RNA
MMHHMPGL_00639 3.3e-172 coaA 2.7.1.33 F Pantothenic acid kinase
MMHHMPGL_00640 4.6e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
MMHHMPGL_00641 1.2e-230 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MMHHMPGL_00642 3.2e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MMHHMPGL_00643 1.9e-68 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MMHHMPGL_00644 1.1e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MMHHMPGL_00645 4.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MMHHMPGL_00646 3.5e-178 yufP S Belongs to the binding-protein-dependent transport system permease family
MMHHMPGL_00647 1.5e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
MMHHMPGL_00648 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MMHHMPGL_00649 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MMHHMPGL_00650 3.2e-78 ypmB S Protein conserved in bacteria
MMHHMPGL_00651 2.1e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MMHHMPGL_00652 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MMHHMPGL_00653 1.7e-19
MMHHMPGL_00654 8.6e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MMHHMPGL_00655 5.7e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MMHHMPGL_00656 1.5e-82 queD 4.1.2.50, 4.2.3.12 H synthase
MMHHMPGL_00657 3.2e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MMHHMPGL_00658 1.9e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MMHHMPGL_00659 5.9e-135 yejC S cyclic nucleotide-binding protein
MMHHMPGL_00660 5.9e-163 rapZ S Displays ATPase and GTPase activities
MMHHMPGL_00661 4.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MMHHMPGL_00662 9.7e-161 whiA K May be required for sporulation
MMHHMPGL_00663 3.6e-276 pepD E Dipeptidase
MMHHMPGL_00664 3.1e-150 XK27_10720 D peptidase activity
MMHHMPGL_00665 1.7e-295 adcA P Belongs to the bacterial solute-binding protein 9 family
MMHHMPGL_00666 9.8e-09
MMHHMPGL_00668 2e-167 yeiH S Membrane
MMHHMPGL_00669 1e-128 mur1 NU muramidase
MMHHMPGL_00670 7.6e-166 cpsY K Transcriptional regulator
MMHHMPGL_00671 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MMHHMPGL_00672 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
MMHHMPGL_00673 3.1e-105 artQ P ABC transporter (Permease
MMHHMPGL_00674 1.2e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_00675 9.3e-158 aatB ET ABC transporter substrate-binding protein
MMHHMPGL_00676 7e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMHHMPGL_00677 3.4e-52
MMHHMPGL_00678 2.7e-45
MMHHMPGL_00679 4.5e-191 adhP 1.1.1.1 C alcohol dehydrogenase
MMHHMPGL_00680 2.6e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MMHHMPGL_00681 8e-123 gntR1 K transcriptional
MMHHMPGL_00682 1.5e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MMHHMPGL_00683 7.2e-257 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MMHHMPGL_00684 6.1e-83 niaX
MMHHMPGL_00685 2.3e-87 niaR S small molecule binding protein (contains 3H domain)
MMHHMPGL_00686 7.6e-126 K DNA-binding helix-turn-helix protein
MMHHMPGL_00687 4.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MMHHMPGL_00688 6.5e-126 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMHHMPGL_00689 4.7e-139 GK ROK family
MMHHMPGL_00690 1.1e-150 dprA LU DNA protecting protein DprA
MMHHMPGL_00691 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MMHHMPGL_00692 2.7e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MMHHMPGL_00693 2.9e-51 V ABC-2 family transporter protein
MMHHMPGL_00695 6.3e-143 S TraX protein
MMHHMPGL_00696 9.2e-121 KT Transcriptional regulatory protein, C terminal
MMHHMPGL_00697 1.8e-227 T PhoQ Sensor
MMHHMPGL_00698 5.3e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MMHHMPGL_00699 1.8e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MMHHMPGL_00700 5e-50 pspE P Rhodanese-like protein
MMHHMPGL_00701 1.3e-137 IQ Acetoin reductase
MMHHMPGL_00703 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MMHHMPGL_00706 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MMHHMPGL_00707 1.1e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MMHHMPGL_00708 4.9e-72 mgrA K Transcriptional regulator, MarR family
MMHHMPGL_00709 2.7e-141 1.6.5.2 GM epimerase
MMHHMPGL_00710 2.1e-121 proV E abc transporter atp-binding protein
MMHHMPGL_00711 4.4e-251 proWX P ABC transporter
MMHHMPGL_00712 1.8e-139 S Phenazine biosynthesis protein
MMHHMPGL_00713 6.9e-18 pnuC H nicotinamide mononucleotide transporter
MMHHMPGL_00714 1.3e-89 2.7.7.65 T phosphorelay sensor kinase activity
MMHHMPGL_00715 7.6e-130 cbiQ P cobalt transport
MMHHMPGL_00716 2.8e-154 P ABC transporter
MMHHMPGL_00717 1.1e-147 cbiO2 P ABC transporter, ATP-binding protein
MMHHMPGL_00718 1.6e-57 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
MMHHMPGL_00719 3.6e-193 yegU O ADP-ribosylglycohydrolase
MMHHMPGL_00720 9.4e-253 F Belongs to the purine-cytosine permease (2.A.39) family
MMHHMPGL_00721 1.5e-166 G Belongs to the carbohydrate kinase PfkB family
MMHHMPGL_00722 2e-61 pnuC H nicotinamide mononucleotide transporter
MMHHMPGL_00724 4.1e-54 S Protein of unknown function with HXXEE motif
MMHHMPGL_00725 7.8e-100 K Transcriptional regulator, TetR family
MMHHMPGL_00726 4.1e-156 czcD P cation diffusion facilitator family transporter
MMHHMPGL_00727 8.2e-191 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MMHHMPGL_00728 7.6e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MMHHMPGL_00729 7.8e-27 L PFAM Integrase catalytic region
MMHHMPGL_00730 1.6e-64 copY K Copper transport repressor, CopY TcrY family
MMHHMPGL_00731 6.9e-65 silP 1.9.3.1, 3.6.3.54 S cog cog4633
MMHHMPGL_00732 0.0 copA 3.6.3.54 P P-type ATPase
MMHHMPGL_00733 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MMHHMPGL_00734 2.9e-120 ybhF_2 V abc transporter atp-binding protein
MMHHMPGL_00735 6.9e-174 ybhR V ABC-2 family transporter protein
MMHHMPGL_00736 9.1e-110 K Bacterial regulatory proteins, tetR family
MMHHMPGL_00737 4e-136 2.4.2.3 F Phosphorylase superfamily
MMHHMPGL_00738 2.3e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MMHHMPGL_00739 0.0 V Type III restriction enzyme, res subunit
MMHHMPGL_00740 2.9e-179 P abc-type fe3 -hydroxamate transport system, periplasmic component
MMHHMPGL_00741 8.1e-233 dinF V Mate efflux family protein
MMHHMPGL_00742 3e-263
MMHHMPGL_00743 4.2e-172 mutR K Helix-turn-helix XRE-family like proteins
MMHHMPGL_00747 1.6e-284 yhaI L Membrane
MMHHMPGL_00748 0.0 ypuA S secreted protein
MMHHMPGL_00749 1.1e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MMHHMPGL_00750 4.7e-143 S TraX protein
MMHHMPGL_00751 2.1e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MMHHMPGL_00752 7e-147 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MMHHMPGL_00753 8.5e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MMHHMPGL_00754 5.9e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MMHHMPGL_00755 2.6e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MMHHMPGL_00756 5.3e-262 nylA 3.5.1.4 J Belongs to the amidase family
MMHHMPGL_00757 4e-153 yckB ET Belongs to the bacterial solute-binding protein 3 family
MMHHMPGL_00758 6.2e-85 yecS P ABC transporter (Permease
MMHHMPGL_00759 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MMHHMPGL_00760 2.5e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MMHHMPGL_00761 2.1e-241 agcS E (Alanine) symporter
MMHHMPGL_00762 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MMHHMPGL_00763 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
MMHHMPGL_00764 5.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MMHHMPGL_00765 2.6e-109 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MMHHMPGL_00766 6.8e-34 M1-755 P Hemerythrin HHE cation binding domain protein
MMHHMPGL_00767 5.1e-243 XK27_04775 S hemerythrin HHE cation binding domain
MMHHMPGL_00768 6.5e-157 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MMHHMPGL_00769 2e-166 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MMHHMPGL_00770 3.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MMHHMPGL_00771 1e-44 yktA S Belongs to the UPF0223 family
MMHHMPGL_00772 4.6e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MMHHMPGL_00773 1.3e-254 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MMHHMPGL_00774 4.5e-155 pstS P phosphate
MMHHMPGL_00775 4.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
MMHHMPGL_00776 1.2e-155 pstA P phosphate transport system permease
MMHHMPGL_00777 1.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMHHMPGL_00778 1.6e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMHHMPGL_00779 1.1e-113 phoU P Plays a role in the regulation of phosphate uptake
MMHHMPGL_00780 0.0 pepN 3.4.11.2 E aminopeptidase
MMHHMPGL_00781 1.9e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MMHHMPGL_00782 1.2e-185 lplA 6.3.1.20 H Lipoate-protein ligase
MMHHMPGL_00783 4.3e-38
MMHHMPGL_00784 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MMHHMPGL_00785 6.6e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MMHHMPGL_00786 5.1e-179 malR K Transcriptional regulator
MMHHMPGL_00787 5.6e-228 malX G ABC transporter
MMHHMPGL_00788 2.7e-252 malF P ABC transporter (Permease
MMHHMPGL_00789 1.3e-151 malG P ABC transporter (Permease
MMHHMPGL_00790 1e-212 msmX P Belongs to the ABC transporter superfamily
MMHHMPGL_00791 6.7e-24 tatA U protein secretion
MMHHMPGL_00792 1.7e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MMHHMPGL_00793 2.3e-293 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MMHHMPGL_00794 8.4e-229 ycdB P peroxidase
MMHHMPGL_00795 1.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
MMHHMPGL_00796 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MMHHMPGL_00797 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
MMHHMPGL_00798 0.0 3.5.1.28 NU amidase activity
MMHHMPGL_00799 0.0 lpdA 1.8.1.4 C Dehydrogenase
MMHHMPGL_00800 2e-202 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MMHHMPGL_00801 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MMHHMPGL_00802 3.5e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MMHHMPGL_00803 2.3e-204 hpk9 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_00804 1.7e-235 T protein histidine kinase activity
MMHHMPGL_00805 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_00806 1.2e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MMHHMPGL_00807 1.7e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MMHHMPGL_00808 4.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MMHHMPGL_00809 1.8e-251 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MMHHMPGL_00810 1e-156 rssA S Phospholipase, patatin family
MMHHMPGL_00811 2.2e-92 estA E Lysophospholipase L1 and related esterases
MMHHMPGL_00812 3.7e-202 S hmm pf01594
MMHHMPGL_00813 6.2e-100 G Belongs to the phosphoglycerate mutase family
MMHHMPGL_00814 1.2e-114 G Belongs to the phosphoglycerate mutase family
MMHHMPGL_00816 2.4e-195 wbbI M transferase activity, transferring glycosyl groups
MMHHMPGL_00817 2.8e-198 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MMHHMPGL_00818 2e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
MMHHMPGL_00819 1.1e-251 epsU S Polysaccharide biosynthesis protein
MMHHMPGL_00820 3.2e-132 cps3F
MMHHMPGL_00821 1.8e-198 M Glycosyltransferase like family 2
MMHHMPGL_00822 2.7e-185
MMHHMPGL_00823 1.7e-124 Z012_10770 M Domain of unknown function (DUF1919)
MMHHMPGL_00824 2.3e-215 wcoF M Glycosyltransferase, group 1 family protein
MMHHMPGL_00825 8.4e-226 rgpAc GT4 M group 1 family protein
MMHHMPGL_00826 3e-259 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MMHHMPGL_00827 2.2e-110 cpsD D COG0489 ATPases involved in chromosome partitioning
MMHHMPGL_00828 1.1e-116 cps4C M biosynthesis protein
MMHHMPGL_00829 2.7e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MMHHMPGL_00830 1.8e-238 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MMHHMPGL_00831 1.7e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MMHHMPGL_00832 2.2e-136 yfeJ 6.3.5.2 F glutamine amidotransferase
MMHHMPGL_00833 3.4e-209 clcA_2 P chloride
MMHHMPGL_00834 7.8e-146 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MMHHMPGL_00835 1.2e-89 S Protein of unknown function (DUF1697)
MMHHMPGL_00836 1e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MMHHMPGL_00837 8.9e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MMHHMPGL_00838 2.1e-260 V Glucan-binding protein C
MMHHMPGL_00839 1.1e-273 V Glucan-binding protein C
MMHHMPGL_00840 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
MMHHMPGL_00841 1.2e-274 pepV 3.5.1.18 E Dipeptidase
MMHHMPGL_00842 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MMHHMPGL_00843 1.5e-80 XK27_03610 K Gnat family
MMHHMPGL_00844 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MMHHMPGL_00845 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MMHHMPGL_00846 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MMHHMPGL_00847 9.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MMHHMPGL_00848 7.2e-17 M LysM domain
MMHHMPGL_00849 1e-90 ebsA S Family of unknown function (DUF5322)
MMHHMPGL_00850 6.3e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MMHHMPGL_00851 0.0 amiC 3.5.1.28 NU Muramidase (Flagellum-specific)
MMHHMPGL_00852 2.4e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MMHHMPGL_00853 2.9e-221 G COG0457 FOG TPR repeat
MMHHMPGL_00854 2.1e-176 yubA S permease
MMHHMPGL_00855 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MMHHMPGL_00856 3.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MMHHMPGL_00857 1.1e-124 ftsE D cell division ATP-binding protein FtsE
MMHHMPGL_00858 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MMHHMPGL_00859 4e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MMHHMPGL_00860 4.9e-159 yjjH S Calcineurin-like phosphoesterase
MMHHMPGL_00861 1.2e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MMHHMPGL_00862 0.0 pacL 3.6.3.8 P cation transport ATPase
MMHHMPGL_00863 8.5e-66 ywiB S Domain of unknown function (DUF1934)
MMHHMPGL_00864 2.9e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
MMHHMPGL_00865 6e-146 yidA S hydrolases of the HAD superfamily
MMHHMPGL_00866 1.5e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MMHHMPGL_00867 7.9e-58 S Protein of unknown function (DUF454)
MMHHMPGL_00868 2.7e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MMHHMPGL_00869 3.4e-231 vicK 2.7.13.3 T Histidine kinase
MMHHMPGL_00870 4.5e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MMHHMPGL_00871 3.7e-36 comGC U Required for transformation and DNA binding
MMHHMPGL_00872 1e-67 cglD NU Competence protein
MMHHMPGL_00873 1.3e-21 NU Type II secretory pathway pseudopilin
MMHHMPGL_00874 5.8e-71 comGF U Competence protein ComGF
MMHHMPGL_00875 1.1e-12 comGF U Putative Competence protein ComGF
MMHHMPGL_00876 1.9e-175 ytxK 2.1.1.72 L DNA methylase
MMHHMPGL_00877 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMHHMPGL_00878 8.8e-27 lanR K DNA-binding helix-turn-helix protein
MMHHMPGL_00879 2.7e-104 V CAAX protease self-immunity
MMHHMPGL_00881 1.6e-93 S CAAX amino terminal protease family protein
MMHHMPGL_00882 1.8e-128 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMHHMPGL_00883 8.6e-201 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MMHHMPGL_00885 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MMHHMPGL_00886 3.3e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMHHMPGL_00887 6.6e-190 yeeE S Sulphur transport
MMHHMPGL_00888 2.4e-36 yeeD O sulfur carrier activity
MMHHMPGL_00889 1.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MMHHMPGL_00890 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MMHHMPGL_00894 9.1e-158 rrmA 2.1.1.187 Q methyltransferase
MMHHMPGL_00895 6.8e-120 S HAD hydrolase, family IA, variant
MMHHMPGL_00896 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MMHHMPGL_00897 2.1e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MMHHMPGL_00898 1.7e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MMHHMPGL_00899 8.8e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MMHHMPGL_00900 3.5e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MMHHMPGL_00901 8.8e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MMHHMPGL_00902 1.9e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
MMHHMPGL_00903 8.6e-66 fnt P Formate nitrite transporter
MMHHMPGL_00904 3.3e-44 fnt P Formate nitrite transporter
MMHHMPGL_00905 2.7e-230 XK27_09615 C reductase
MMHHMPGL_00906 1.6e-108 XK27_09620 S FMN reductase (NADPH) activity
MMHHMPGL_00907 2.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MMHHMPGL_00908 4.2e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
MMHHMPGL_00909 2e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MMHHMPGL_00910 5.9e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
MMHHMPGL_00911 4.6e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MMHHMPGL_00912 9.1e-153 K Transcriptional activator, Rgg GadR MutR family
MMHHMPGL_00913 3.5e-08 S Lantibiotic alpha
MMHHMPGL_00915 2.5e-141 lanM V type 2 lantibiotic biosynthesis protein LanM
MMHHMPGL_00916 9e-125 3.6.3.27 V ABC transporter
MMHHMPGL_00917 2.4e-146 lanM V Lanthionine synthetase C family protein
MMHHMPGL_00918 1.8e-68 1.6.5.5 C alcohol dehydrogenase
MMHHMPGL_00919 2.3e-148 V abc transporter atp-binding protein
MMHHMPGL_00920 2.8e-38
MMHHMPGL_00921 1.3e-42
MMHHMPGL_00924 3.8e-130 clpB O C-terminal, D2-small domain, of ClpB protein
MMHHMPGL_00926 8.8e-45
MMHHMPGL_00927 2e-53 I mechanosensitive ion channel activity
MMHHMPGL_00928 2.5e-96 fic D nucleotidyltransferase activity
MMHHMPGL_00929 4.6e-25
MMHHMPGL_00930 9.1e-14 L Transposase and inactivated derivatives
MMHHMPGL_00931 1.8e-09 L Integrase core domain protein
MMHHMPGL_00932 3.4e-25 L transposase activity
MMHHMPGL_00934 9.2e-100 KT Transcriptional regulatory protein, C terminal
MMHHMPGL_00935 1.6e-166 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MMHHMPGL_00937 4.9e-102 ubiE Q Methyltransferase
MMHHMPGL_00938 4.9e-20 S Ribosomal protein S1-like RNA-binding domain
MMHHMPGL_00940 2.1e-127 U TraM recognition site of TraD and TraG
MMHHMPGL_00951 5.4e-16 L Transposase, IS605 OrfB family
MMHHMPGL_00954 3.6e-33 S Single-strand binding protein family
MMHHMPGL_00955 3.4e-67 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MMHHMPGL_00956 2.7e-07 S ERF superfamily
MMHHMPGL_00961 1.6e-29 radC E Belongs to the UPF0758 family
MMHHMPGL_00963 2.9e-09 panZ K Acetyltransferase (GNAT) domain
MMHHMPGL_00971 2.9e-29 G Part of a membrane complex involved in electron transport
MMHHMPGL_00972 1.1e-51 L Transposase
MMHHMPGL_00973 1.1e-09
MMHHMPGL_00974 0.0 L helicase
MMHHMPGL_00975 6.9e-13
MMHHMPGL_00976 1.2e-34
MMHHMPGL_00979 5.4e-44 traI 5.99.1.2 L Bacterial DNA topoisomeraes I ATP-binding domain
MMHHMPGL_00980 1.5e-50 traI 5.99.1.2 L DNA topoisomerase
MMHHMPGL_00983 1.9e-14 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
MMHHMPGL_00984 7.6e-131 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MMHHMPGL_00985 1.4e-31
MMHHMPGL_00986 6.1e-20
MMHHMPGL_00987 9.3e-107
MMHHMPGL_00988 2.9e-257 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMHHMPGL_00989 5.8e-53
MMHHMPGL_00991 2.8e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MMHHMPGL_00992 1.8e-89 L Transposase
MMHHMPGL_00993 5.9e-11 acpT 2.7.8.7 H 4'-phosphopantetheinyl transferase superfamily
MMHHMPGL_00994 7.2e-44 fabD 2.3.1.39 I Acyl transferase domain
MMHHMPGL_00995 3e-21 bacT Q thioesterase involved in non-ribosomal peptide biosynthesis
MMHHMPGL_00996 2.4e-169 pksJ IQ PKS_DH
MMHHMPGL_00997 4.1e-38 Q Ketoacyl-synthetase C-terminal extension
MMHHMPGL_00998 3.3e-171 pksM3 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMHHMPGL_00999 3.1e-103 Q Belongs to the ATP-dependent AMP-binding enzyme family
MMHHMPGL_01000 6.3e-58 K Psort location Cytoplasmic, score
MMHHMPGL_01001 3.2e-81 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MMHHMPGL_01002 4.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MMHHMPGL_01003 3.4e-14 rpmH J Ribosomal protein L34
MMHHMPGL_01004 1.7e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
MMHHMPGL_01005 8.4e-97 K Transcriptional regulator
MMHHMPGL_01006 1.3e-153 jag S RNA-binding protein
MMHHMPGL_01007 9.8e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMHHMPGL_01008 2.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MMHHMPGL_01009 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
MMHHMPGL_01010 2.9e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MMHHMPGL_01011 1.7e-134 fasA KT Response regulator of the LytR AlgR family
MMHHMPGL_01012 1.9e-242 fasC T protein histidine kinase activity
MMHHMPGL_01013 2.5e-239 hpk9 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_01014 3.1e-156 hpk9 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_01015 1.8e-229 2.7.13.3 T Histidine kinase
MMHHMPGL_01016 1.6e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MMHHMPGL_01017 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MMHHMPGL_01018 1.2e-118 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MMHHMPGL_01019 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MMHHMPGL_01020 7.8e-50 S Protein of unknown function (DUF3397)
MMHHMPGL_01021 2e-79 perR P Belongs to the Fur family
MMHHMPGL_01023 3.5e-41 xisC L viral genome integration into host DNA
MMHHMPGL_01025 8e-14
MMHHMPGL_01027 1.9e-113 U AAA-like domain
MMHHMPGL_01028 1.3e-28
MMHHMPGL_01030 1.8e-69 spaG S ABC-2 family transporter protein
MMHHMPGL_01031 3.1e-96 spaE S ABC-2 family transporter protein
MMHHMPGL_01032 3.2e-116 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MMHHMPGL_01033 0.0 V (ABC) transporter
MMHHMPGL_01034 7.2e-175 spaC2 V Lanthionine synthetase C-like protein
MMHHMPGL_01035 9.8e-266 spaT V ABC transporter
MMHHMPGL_01037 7.9e-32 yqgQ S protein conserved in bacteria
MMHHMPGL_01038 1.2e-177 glk 2.7.1.2 G Glucokinase
MMHHMPGL_01039 0.0 typA T GTP-binding protein TypA
MMHHMPGL_01040 9.6e-08 S Protein of unknown function (DUF3165)
MMHHMPGL_01041 1.3e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MMHHMPGL_01042 4.1e-195 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MMHHMPGL_01043 2.3e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MMHHMPGL_01044 2.9e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MMHHMPGL_01045 1.2e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MMHHMPGL_01046 3.5e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MMHHMPGL_01047 7e-81 sepF D cell septum assembly
MMHHMPGL_01048 3e-35 yggT D integral membrane protein
MMHHMPGL_01049 5.5e-144 ylmH S conserved protein, contains S4-like domain
MMHHMPGL_01050 1.1e-23 divIVA D regulation of cell shape
MMHHMPGL_01051 1.3e-135 divIVA D Cell division initiation protein
MMHHMPGL_01052 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MMHHMPGL_01053 6.5e-73 M Pilin isopeptide linkage domain protein
MMHHMPGL_01055 1.5e-09
MMHHMPGL_01057 1.2e-32
MMHHMPGL_01059 4e-21 S DNA binding
MMHHMPGL_01060 2.8e-07 K sequence-specific DNA binding
MMHHMPGL_01061 1.8e-45 XK27_10050 K Peptidase S24-like
MMHHMPGL_01062 9.9e-17 S Short C-terminal domain
MMHHMPGL_01063 1.2e-165 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
MMHHMPGL_01064 6.9e-121 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
MMHHMPGL_01068 6.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MMHHMPGL_01069 9.9e-123 comFC S Competence protein
MMHHMPGL_01070 6.5e-251 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MMHHMPGL_01071 2e-109 yvyE 3.4.13.9 S YigZ family
MMHHMPGL_01072 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MMHHMPGL_01073 2.1e-112 acuB S CBS domain
MMHHMPGL_01074 7.4e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MMHHMPGL_01075 1.6e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MMHHMPGL_01076 1.8e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MMHHMPGL_01077 6.5e-146 livH E Belongs to the binding-protein-dependent transport system permease family
MMHHMPGL_01078 8.2e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MMHHMPGL_01079 1.6e-45 ylbG S UPF0298 protein
MMHHMPGL_01080 1.6e-71 ylbF S Belongs to the UPF0342 family
MMHHMPGL_01081 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MMHHMPGL_01082 2.8e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MMHHMPGL_01083 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MMHHMPGL_01084 1.4e-220 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MMHHMPGL_01085 1.3e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
MMHHMPGL_01086 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MMHHMPGL_01087 7.7e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MMHHMPGL_01088 6e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MMHHMPGL_01089 1.2e-227 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MMHHMPGL_01090 2.4e-101 yvdD 3.2.2.10 L Belongs to the LOG family
MMHHMPGL_01091 5.6e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MMHHMPGL_01092 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MMHHMPGL_01093 7.6e-46 ylxQ J ribosomal protein
MMHHMPGL_01094 1.4e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MMHHMPGL_01095 7.1e-196 nusA K Participates in both transcription termination and antitermination
MMHHMPGL_01096 1.3e-79 rimP S Required for maturation of 30S ribosomal subunits
MMHHMPGL_01097 9.8e-188 brpA K Transcriptional
MMHHMPGL_01098 5.3e-87 XK27_05885 2.3.1.82 M Acetyltransferase (GNAT) domain
MMHHMPGL_01099 2.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MMHHMPGL_01100 4e-246 pbuO S permease
MMHHMPGL_01101 2.3e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MMHHMPGL_01102 1.4e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MMHHMPGL_01103 1.2e-167 manL 2.7.1.191 G pts system
MMHHMPGL_01104 3.6e-135 manY G pts system
MMHHMPGL_01105 1.4e-164 manN G PTS system mannose fructose sorbose family IID component
MMHHMPGL_01106 1.5e-67 manO S Protein conserved in bacteria
MMHHMPGL_01107 2.5e-178 manL 2.7.1.191 G pts system
MMHHMPGL_01108 3.4e-117 manM G pts system
MMHHMPGL_01109 2.8e-168 manN G PTS system mannose fructose sorbose family IID component
MMHHMPGL_01110 3.8e-63 manO S protein conserved in bacteria
MMHHMPGL_01111 1.7e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MMHHMPGL_01112 1.1e-113
MMHHMPGL_01113 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MMHHMPGL_01114 1.7e-165 dnaI L Primosomal protein DnaI
MMHHMPGL_01115 3e-215 dnaB L Replication initiation and membrane attachment
MMHHMPGL_01116 3.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MMHHMPGL_01117 2.2e-282 T PhoQ Sensor
MMHHMPGL_01118 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MMHHMPGL_01119 1.1e-90 yceD K metal-binding, possibly nucleic acid-binding protein
MMHHMPGL_01120 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MMHHMPGL_01121 6.8e-243 P COG0168 Trk-type K transport systems, membrane components
MMHHMPGL_01122 2.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
MMHHMPGL_01123 1.1e-147 cbiQ P cobalt transport
MMHHMPGL_01124 0.0 ykoD P abc transporter atp-binding protein
MMHHMPGL_01125 2.7e-94 S UPF0397 protein
MMHHMPGL_01126 1.1e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MMHHMPGL_01127 1.3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MMHHMPGL_01128 2e-73 metI P ABC transporter (Permease
MMHHMPGL_01129 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MMHHMPGL_01130 2.9e-262 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MMHHMPGL_01131 3.9e-162 metQ M Belongs to the NlpA lipoprotein family
MMHHMPGL_01132 2.3e-143 ET ABC transporter substrate-binding protein
MMHHMPGL_01133 1.6e-131 cbiO P ABC transporter
MMHHMPGL_01134 4.4e-138 P Cobalt transport protein
MMHHMPGL_01135 1.3e-174 cbiM P PDGLE domain
MMHHMPGL_01136 5.4e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MMHHMPGL_01137 1.1e-110 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MMHHMPGL_01138 1.2e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MMHHMPGL_01139 3.9e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MMHHMPGL_01140 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MMHHMPGL_01141 1.7e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MMHHMPGL_01142 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MMHHMPGL_01143 1.8e-95 ureI S AmiS/UreI family transporter
MMHHMPGL_01144 2e-250 S Domain of unknown function (DUF4173)
MMHHMPGL_01145 9.9e-55 yhaI L Membrane
MMHHMPGL_01146 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMHHMPGL_01147 1.7e-104 K sequence-specific DNA binding
MMHHMPGL_01148 3.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MMHHMPGL_01149 5.5e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MMHHMPGL_01150 2.2e-93 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MMHHMPGL_01151 7.6e-247 trkA P Potassium transporter peripheral membrane component
MMHHMPGL_01152 2.1e-255 trkH P Cation transport protein
MMHHMPGL_01153 3.3e-42 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MMHHMPGL_01154 2.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMHHMPGL_01155 4.4e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MMHHMPGL_01156 4.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MMHHMPGL_01157 6.1e-132 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MMHHMPGL_01158 4.1e-86 ykuL S CBS domain
MMHHMPGL_01159 9.3e-100 XK27_09740 S Phosphoesterase
MMHHMPGL_01160 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MMHHMPGL_01161 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MMHHMPGL_01162 4.6e-36 yneF S UPF0154 protein
MMHHMPGL_01163 1.1e-90 K transcriptional regulator
MMHHMPGL_01164 4e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MMHHMPGL_01165 3.5e-11 ycdA S Domain of unknown function (DUF5105)
MMHHMPGL_01166 2.5e-108 ybhL S Belongs to the BI1 family
MMHHMPGL_01167 9.6e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MMHHMPGL_01168 3.2e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMHHMPGL_01169 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MMHHMPGL_01170 1.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMHHMPGL_01171 2.1e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MMHHMPGL_01172 1.1e-281 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MMHHMPGL_01173 7.7e-80 XK27_09675 K -acetyltransferase
MMHHMPGL_01174 4e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MMHHMPGL_01175 4.1e-21 XK27_11680
MMHHMPGL_01176 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MMHHMPGL_01177 3.9e-292 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MMHHMPGL_01178 9.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MMHHMPGL_01179 2.1e-49 gpsB D regulation of cell shape
MMHHMPGL_01180 2.9e-93 ypsA S Belongs to the UPF0398 family
MMHHMPGL_01181 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MMHHMPGL_01182 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MMHHMPGL_01183 1.7e-254 pepC 3.4.22.40 E aminopeptidase
MMHHMPGL_01184 1.7e-73 yhaI S Protein of unknown function (DUF805)
MMHHMPGL_01185 3.8e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MMHHMPGL_01186 3.8e-276 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MMHHMPGL_01187 9.4e-210 macB_2 V FtsX-like permease family
MMHHMPGL_01188 1.5e-121 yhcA V abc transporter atp-binding protein
MMHHMPGL_01189 2.6e-121 mta K Transcriptional
MMHHMPGL_01190 1.8e-29 S Protein of unknown function (DUF3021)
MMHHMPGL_01191 3.8e-73 K COG3279 Response regulator of the LytR AlgR family
MMHHMPGL_01192 2.6e-136 cylB V ABC-2 type transporter
MMHHMPGL_01193 8.9e-156 cylA V abc transporter atp-binding protein
MMHHMPGL_01194 8.8e-53 K regulation of RNA biosynthetic process
MMHHMPGL_01195 2e-46 3.2.2.21 S YCII-related domain
MMHHMPGL_01196 5e-40 yjdF S Protein of unknown function (DUF2992)
MMHHMPGL_01197 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMHHMPGL_01198 3.4e-135 glcR K transcriptional regulator (DeoR family)
MMHHMPGL_01199 8.6e-145 cof S Sucrose-6F-phosphate phosphohydrolase
MMHHMPGL_01200 2.6e-80 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Psort location CytoplasmicMembrane, score
MMHHMPGL_01201 6.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MMHHMPGL_01202 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
MMHHMPGL_01203 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MMHHMPGL_01204 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MMHHMPGL_01205 2.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMHHMPGL_01206 7.6e-55 S TM2 domain
MMHHMPGL_01207 1.9e-47
MMHHMPGL_01209 3.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MMHHMPGL_01210 1.1e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MMHHMPGL_01211 6.8e-142 cmpC S abc transporter atp-binding protein
MMHHMPGL_01212 0.0 WQ51_06230 S ABC transporter substrate binding protein
MMHHMPGL_01213 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MMHHMPGL_01214 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MMHHMPGL_01215 1.9e-144 cdsA 2.7.7.41 S Belongs to the CDS family
MMHHMPGL_01216 5e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MMHHMPGL_01217 2.8e-41 yajC U protein transport
MMHHMPGL_01218 3e-125 yeeN K transcriptional regulatory protein
MMHHMPGL_01219 4e-279 V ABC transporter
MMHHMPGL_01220 6.9e-148 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MMHHMPGL_01221 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
MMHHMPGL_01222 8.3e-156 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MMHHMPGL_01223 0.0 ptsG 2.7.1.199, 2.7.1.208 G pts system
MMHHMPGL_01224 3.4e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MMHHMPGL_01225 1.3e-129 adcB P ABC transporter (Permease
MMHHMPGL_01226 9.9e-137 adcC P ABC transporter, ATP-binding protein
MMHHMPGL_01227 3.5e-71 adcR K transcriptional
MMHHMPGL_01228 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MMHHMPGL_01229 1.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MMHHMPGL_01230 4e-25
MMHHMPGL_01231 3.8e-168 oppF P Belongs to the ABC transporter superfamily
MMHHMPGL_01232 7.3e-197 oppD P Belongs to the ABC transporter superfamily
MMHHMPGL_01233 7.3e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMHHMPGL_01234 5.1e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMHHMPGL_01235 4.6e-310 oppA E ABC transporter substrate-binding protein
MMHHMPGL_01236 5.9e-274 sufB O assembly protein SufB
MMHHMPGL_01237 3.3e-74 nifU C SUF system FeS assembly protein, NifU family
MMHHMPGL_01238 3.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MMHHMPGL_01239 9.1e-234 sufD O assembly protein SufD
MMHHMPGL_01240 2.8e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MMHHMPGL_01241 6.7e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
MMHHMPGL_01242 9.5e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MMHHMPGL_01243 1.8e-17 S Protein of unknown function (DUF3021)
MMHHMPGL_01244 4.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MMHHMPGL_01245 1.8e-271 glnP P ABC transporter
MMHHMPGL_01246 5e-123 glnQ E abc transporter atp-binding protein
MMHHMPGL_01247 2.1e-189 D nuclear chromosome segregation
MMHHMPGL_01248 1.7e-73 V VanZ like family
MMHHMPGL_01249 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MMHHMPGL_01250 6.9e-196 yhjX P Major Facilitator
MMHHMPGL_01251 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MMHHMPGL_01252 2.8e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MMHHMPGL_01253 1e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MMHHMPGL_01254 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MMHHMPGL_01255 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MMHHMPGL_01256 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MMHHMPGL_01257 9.8e-85 nrdI F Belongs to the NrdI family
MMHHMPGL_01258 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MMHHMPGL_01259 4.5e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MMHHMPGL_01260 5e-176 prmA J Ribosomal protein L11 methyltransferase
MMHHMPGL_01261 3.5e-82 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MMHHMPGL_01262 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
MMHHMPGL_01263 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MMHHMPGL_01264 2e-71 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MMHHMPGL_01265 1.8e-221 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MMHHMPGL_01266 1e-148 ykuT M mechanosensitive ion channel
MMHHMPGL_01267 5e-79 sigH K DNA-templated transcription, initiation
MMHHMPGL_01272 6e-07 sraP UW domain, Protein
MMHHMPGL_01273 1.6e-252 T PhoQ Sensor
MMHHMPGL_01274 3.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MMHHMPGL_01275 2.9e-11 V Lantibiotic transport processing ATP-binding protein
MMHHMPGL_01276 2.5e-164 bcrA V abc transporter atp-binding protein
MMHHMPGL_01277 3.1e-120 S ABC-2 family transporter protein
MMHHMPGL_01278 1.6e-121 S ABC-2 family transporter protein
MMHHMPGL_01280 1e-20 L Transposase IS116 IS110 IS902
MMHHMPGL_01283 4.3e-49 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01284 1.7e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MMHHMPGL_01285 4.3e-49 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01286 7e-142 peb1A ET Belongs to the bacterial solute-binding protein 3 family
MMHHMPGL_01287 1.5e-62 gltJ P ABC transporter (Permease
MMHHMPGL_01288 2.2e-111 tcyB_2 P ABC transporter (permease)
MMHHMPGL_01289 9.3e-77 L transposase IS116 IS110 IS902 family
MMHHMPGL_01290 2.4e-105 csn2 S CRISPR-associated protein (Cas_Csn2)
MMHHMPGL_01291 2.7e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MMHHMPGL_01292 2.3e-159 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MMHHMPGL_01293 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MMHHMPGL_01294 9.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
MMHHMPGL_01295 5.1e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MMHHMPGL_01296 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMHHMPGL_01297 6.9e-101 3.1.3.18 S IA, variant 1
MMHHMPGL_01298 1.1e-116 lrgB M LrgB-like family
MMHHMPGL_01299 1.7e-58 lrgA S Effector of murein hydrolase LrgA
MMHHMPGL_01301 8.3e-60 arsC 1.20.4.1 P Belongs to the ArsC family
MMHHMPGL_01302 3.6e-75 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MMHHMPGL_01303 1.4e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMHHMPGL_01304 5.1e-104 wecD M Acetyltransferase (GNAT) domain
MMHHMPGL_01305 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MMHHMPGL_01306 6.4e-141 GK ROK family
MMHHMPGL_01307 3e-66 gloA 4.4.1.5 E Lactoylglutathione lyase
MMHHMPGL_01308 4.7e-144 XK27_08050 O HflC and HflK could regulate a protease
MMHHMPGL_01309 4.4e-205 potD P spermidine putrescine ABC transporter
MMHHMPGL_01310 9.5e-133 potC P ABC-type spermidine putrescine transport system, permease component II
MMHHMPGL_01311 1.6e-140 potB P ABC-type spermidine putrescine transport system, permease component I
MMHHMPGL_01312 1.8e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MMHHMPGL_01313 9.5e-169 murB 1.3.1.98 M cell wall formation
MMHHMPGL_01314 2.2e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MMHHMPGL_01315 9.3e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MMHHMPGL_01316 1.4e-278 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MMHHMPGL_01317 1.2e-138 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MMHHMPGL_01318 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
MMHHMPGL_01319 0.0 ydaO E amino acid
MMHHMPGL_01320 3.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MMHHMPGL_01321 9.1e-37 ylqC L Belongs to the UPF0109 family
MMHHMPGL_01322 4.2e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MMHHMPGL_01324 5.4e-237 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_01325 1e-128 agrA KT phosphorelay signal transduction system
MMHHMPGL_01326 1.1e-127 O protein import
MMHHMPGL_01327 2.2e-170 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MMHHMPGL_01328 1.9e-17 yhaI L Membrane
MMHHMPGL_01330 2.2e-156 xth 3.1.11.2 L exodeoxyribonuclease III
MMHHMPGL_01331 5.2e-73 S QueT transporter
MMHHMPGL_01333 5.4e-173 yfjR K regulation of single-species biofilm formation
MMHHMPGL_01335 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MMHHMPGL_01336 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MMHHMPGL_01337 2.8e-85 ccl S cog cog4708
MMHHMPGL_01338 4.9e-160 rbn E Belongs to the UPF0761 family
MMHHMPGL_01339 9.4e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MMHHMPGL_01340 5.6e-231 ytoI K transcriptional regulator containing CBS domains
MMHHMPGL_01341 7.7e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MMHHMPGL_01342 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMHHMPGL_01343 0.0 comEC S Competence protein ComEC
MMHHMPGL_01344 9.8e-113 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MMHHMPGL_01345 6.4e-142 plsC 2.3.1.51 I Acyltransferase
MMHHMPGL_01346 1.2e-172 nodB3 G deacetylase
MMHHMPGL_01347 4.5e-127 yabB 2.1.1.223 L Methyltransferase
MMHHMPGL_01348 1.2e-39 yazA L endonuclease containing a URI domain
MMHHMPGL_01349 1.6e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MMHHMPGL_01350 5.3e-143 corA P CorA-like protein
MMHHMPGL_01351 8.9e-60 yjqA S Bacterial PH domain
MMHHMPGL_01352 6.6e-99 thiT S Thiamine transporter
MMHHMPGL_01355 8.4e-90 Z012_04635 K sequence-specific DNA binding
MMHHMPGL_01356 7.2e-105 V ATPases associated with a variety of cellular activities
MMHHMPGL_01357 1.1e-60
MMHHMPGL_01358 1.7e-143 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MMHHMPGL_01360 1.1e-221 C 4Fe-4S single cluster domain
MMHHMPGL_01361 4.1e-196 yjbB G Permeases of the major facilitator superfamily
MMHHMPGL_01362 4.4e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MMHHMPGL_01363 2.4e-108 ywaF S integral membrane protein
MMHHMPGL_01364 7.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MMHHMPGL_01367 1.1e-153 cjaA ET ABC transporter substrate-binding protein
MMHHMPGL_01368 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01369 1.3e-109 P ABC transporter (Permease
MMHHMPGL_01370 1.1e-113 papP P ABC transporter (Permease
MMHHMPGL_01371 5.7e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MMHHMPGL_01372 1e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
MMHHMPGL_01373 0.0 copA 3.6.3.54 P P-type ATPase
MMHHMPGL_01374 3e-72 copY K negative regulation of transcription, DNA-templated
MMHHMPGL_01375 1.3e-232 L DNA binding domain of tn916 integrase
MMHHMPGL_01376 1.8e-30 xis S Excisionase from transposon Tn916
MMHHMPGL_01377 9.3e-36 S Helix-turn-helix domain
MMHHMPGL_01378 1.1e-71 phyR K Sigma-70, region 4
MMHHMPGL_01379 6e-58 K Helix-turn-helix domain
MMHHMPGL_01380 0.0 tetP J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MMHHMPGL_01381 7.4e-169 S Conjugative transposon protein TcpC
MMHHMPGL_01382 2.2e-190 yddH M NlpC p60 family protein
MMHHMPGL_01383 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_01384 0.0 S AAA-like domain
MMHHMPGL_01385 3.8e-90 S TcpE family
MMHHMPGL_01386 7.5e-91 S Antirestriction protein (ArdA)
MMHHMPGL_01387 1.9e-30 S Psort location CytoplasmicMembrane, score
MMHHMPGL_01388 5.6e-217 L COG3547 Transposase and inactivated derivatives
MMHHMPGL_01389 3.9e-237 L Transposase
MMHHMPGL_01390 3.6e-16
MMHHMPGL_01391 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
MMHHMPGL_01392 4.3e-22 K Replication initiation factor
MMHHMPGL_01393 3e-234 K Replication initiation factor
MMHHMPGL_01394 3.7e-265 D Domain of unknown function DUF87
MMHHMPGL_01395 1e-63 S Bacterial protein of unknown function (DUF961)
MMHHMPGL_01396 2.3e-53 S Bacterial protein of unknown function (DUF961)
MMHHMPGL_01397 1.1e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MMHHMPGL_01398 2e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MMHHMPGL_01399 2e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MMHHMPGL_01400 1.1e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MMHHMPGL_01401 7.3e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MMHHMPGL_01402 1e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MMHHMPGL_01403 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MMHHMPGL_01404 7.1e-38 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
MMHHMPGL_01405 0.0 ctpE P E1-E2 ATPase
MMHHMPGL_01406 9.8e-46
MMHHMPGL_01407 1.1e-11 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MMHHMPGL_01408 6.3e-164 T Diguanylate cyclase
MMHHMPGL_01409 4.9e-20 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MMHHMPGL_01410 5.2e-150 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MMHHMPGL_01411 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
MMHHMPGL_01412 0.0
MMHHMPGL_01413 2e-50 L Belongs to the 'phage' integrase family
MMHHMPGL_01414 7.3e-167 T GHKL domain
MMHHMPGL_01415 3.3e-111 KT COG3279 Response regulator of the LytR AlgR family
MMHHMPGL_01416 8.1e-105
MMHHMPGL_01417 6.6e-135 V ATPase activity
MMHHMPGL_01418 7.6e-143 V 'abc transporter, ATP-binding protein
MMHHMPGL_01419 7.5e-108 I radical SAM domain protein
MMHHMPGL_01421 3.7e-09 S PFAM Abortive infection protein
MMHHMPGL_01426 1.4e-42
MMHHMPGL_01427 8.1e-183 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MMHHMPGL_01428 1.9e-51
MMHHMPGL_01429 9.3e-85 S Plasmid replication protein
MMHHMPGL_01430 5.6e-20 S Domain of unknown function (DUF3173)
MMHHMPGL_01431 9.6e-190 L Pfam:Integrase_AP2
MMHHMPGL_01432 2.1e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MMHHMPGL_01434 5e-125 V abc transporter atp-binding protein
MMHHMPGL_01435 0.0 V ABC transporter (Permease
MMHHMPGL_01436 1e-128 K transcriptional regulator, MerR family
MMHHMPGL_01437 1.6e-103 dnaQ 2.7.7.7 L DNA polymerase III
MMHHMPGL_01438 7e-42 WQ51_02910 S Protein of unknown function, DUF536
MMHHMPGL_01440 1.3e-63 XK27_02560 S cog cog2151
MMHHMPGL_01441 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MMHHMPGL_01442 1.7e-218 ytfP S Flavoprotein
MMHHMPGL_01444 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MMHHMPGL_01445 5.4e-152 ytmP 2.7.1.89 M Phosphotransferase
MMHHMPGL_01446 4.7e-180 ecsB U ABC transporter
MMHHMPGL_01447 4.1e-130 ecsA V abc transporter atp-binding protein
MMHHMPGL_01448 2.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MMHHMPGL_01449 3.1e-12
MMHHMPGL_01451 1.4e-51
MMHHMPGL_01452 4.7e-16
MMHHMPGL_01453 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MMHHMPGL_01454 8.5e-196 ylbM S Belongs to the UPF0348 family
MMHHMPGL_01455 1.3e-139 yqeM Q Methyltransferase domain protein
MMHHMPGL_01456 8.5e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MMHHMPGL_01457 2.5e-86 entB 3.5.1.19 Q Isochorismatase family
MMHHMPGL_01458 9.9e-106 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MMHHMPGL_01459 7e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MMHHMPGL_01460 7.7e-49 yhbY J RNA-binding protein
MMHHMPGL_01461 1.6e-210 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MMHHMPGL_01462 1.4e-98 yqeG S hydrolase of the HAD superfamily
MMHHMPGL_01463 1.2e-147 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MMHHMPGL_01464 1.6e-64
MMHHMPGL_01465 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMHHMPGL_01466 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MMHHMPGL_01467 3.1e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMHHMPGL_01468 2.1e-282 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MMHHMPGL_01469 7.5e-236 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MMHHMPGL_01470 2.3e-167 H COG0463 Glycosyltransferases involved in cell wall biogenesis
MMHHMPGL_01471 2.3e-234 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MMHHMPGL_01472 2.9e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMHHMPGL_01473 6.1e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMHHMPGL_01474 3.1e-153 hlpA M Belongs to the NlpA lipoprotein family
MMHHMPGL_01475 4.4e-100 pncA Q isochorismatase
MMHHMPGL_01476 6.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MMHHMPGL_01477 1.4e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MMHHMPGL_01478 1.5e-74 XK27_03180 T universal stress protein
MMHHMPGL_01480 2.2e-156 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MMHHMPGL_01481 2.6e-07 MU outer membrane autotransporter barrel domain protein
MMHHMPGL_01482 8.9e-240 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MMHHMPGL_01483 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MMHHMPGL_01484 8.7e-24
MMHHMPGL_01485 3.6e-244 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MMHHMPGL_01486 7e-98 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MMHHMPGL_01487 6.6e-22
MMHHMPGL_01488 3.4e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MMHHMPGL_01489 0.0 M Pilin isopeptide linkage domain protein
MMHHMPGL_01490 1.2e-100 K Transcriptional regulator C-terminal region
MMHHMPGL_01492 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MMHHMPGL_01493 1.6e-244 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MMHHMPGL_01495 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MMHHMPGL_01496 6.4e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MMHHMPGL_01497 1.6e-165 S Protein of unknown function (DUF3114)
MMHHMPGL_01498 9.8e-25 S Protein of unknown function (DUF3114)
MMHHMPGL_01499 7e-29 pspC KT PspC domain protein
MMHHMPGL_01500 3.4e-118 yqfA K protein, Hemolysin III
MMHHMPGL_01501 9.5e-77 K hmm pf08876
MMHHMPGL_01502 3.7e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MMHHMPGL_01503 3.9e-207 mvaS 2.3.3.10 I synthase
MMHHMPGL_01504 9.4e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MMHHMPGL_01505 8.1e-93 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MMHHMPGL_01506 4.8e-21
MMHHMPGL_01507 7.5e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MMHHMPGL_01508 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MMHHMPGL_01509 1.1e-248 mmuP E amino acid
MMHHMPGL_01510 1.8e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MMHHMPGL_01511 1.4e-29 S Domain of unknown function (DUF1912)
MMHHMPGL_01512 7.2e-14 L Helix-hairpin-helix DNA-binding motif class 1
MMHHMPGL_01513 4.3e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MMHHMPGL_01514 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMHHMPGL_01515 4e-10
MMHHMPGL_01516 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMHHMPGL_01517 4.8e-201 ilvE 2.6.1.42 E Aminotransferase
MMHHMPGL_01518 6.3e-16 S Protein of unknown function (DUF2969)
MMHHMPGL_01521 1.4e-204 rpsA 1.17.7.4 J ribosomal protein S1
MMHHMPGL_01525 5.5e-107 S Domain of Unknown Function with PDB structure (DUF3862)
MMHHMPGL_01526 4.8e-112 M Pfam SNARE associated Golgi protein
MMHHMPGL_01527 4.4e-233 murN 2.3.2.16 V FemAB family
MMHHMPGL_01528 8.9e-173 S oxidoreductase
MMHHMPGL_01529 1.1e-47 XK27_09445 S Domain of unknown function (DUF1827)
MMHHMPGL_01530 1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MMHHMPGL_01531 0.0 clpE O Belongs to the ClpA ClpB family
MMHHMPGL_01532 9e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MMHHMPGL_01533 1e-34 ykuJ S protein conserved in bacteria
MMHHMPGL_01534 4.9e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MMHHMPGL_01535 3.8e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01536 1.1e-78 feoA P FeoA domain protein
MMHHMPGL_01537 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MMHHMPGL_01538 8.6e-08
MMHHMPGL_01539 1e-150 I Alpha/beta hydrolase family
MMHHMPGL_01540 3.2e-158 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MMHHMPGL_01541 1e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MMHHMPGL_01542 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MMHHMPGL_01543 2.4e-104 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MMHHMPGL_01544 7.1e-150 licT K antiterminator
MMHHMPGL_01545 1.7e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MMHHMPGL_01546 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MMHHMPGL_01547 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MMHHMPGL_01548 2.3e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MMHHMPGL_01549 3.9e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MMHHMPGL_01550 2.9e-221 mdtG EGP Major facilitator Superfamily
MMHHMPGL_01551 2.6e-33 secG U Preprotein translocase subunit SecG
MMHHMPGL_01552 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MMHHMPGL_01553 3.1e-78 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MMHHMPGL_01554 5.9e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MMHHMPGL_01555 2.3e-60 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MMHHMPGL_01556 5.1e-209 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MMHHMPGL_01557 8.6e-179 ccpA K Catabolite control protein A
MMHHMPGL_01558 1.3e-201 yyaQ S YjbR
MMHHMPGL_01559 3.6e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MMHHMPGL_01560 3.3e-77 yueI S Protein of unknown function (DUF1694)
MMHHMPGL_01561 4.8e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MMHHMPGL_01562 6e-25 WQ51_00785
MMHHMPGL_01563 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MMHHMPGL_01564 4.2e-217 ywbD 2.1.1.191 J Methyltransferase
MMHHMPGL_01565 3.6e-120 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MMHHMPGL_01566 2.2e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MMHHMPGL_01567 1.2e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MMHHMPGL_01568 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MMHHMPGL_01569 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MMHHMPGL_01570 4.2e-53 yheA S Belongs to the UPF0342 family
MMHHMPGL_01571 9.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MMHHMPGL_01572 6.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MMHHMPGL_01573 5.5e-78 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MMHHMPGL_01574 4.5e-149 pheA 4.2.1.51 E Prephenate dehydratase
MMHHMPGL_01575 8.4e-244 msrR K Transcriptional regulator
MMHHMPGL_01576 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport
MMHHMPGL_01577 2e-202 I acyl-CoA dehydrogenase
MMHHMPGL_01578 1.3e-96 mip S hydroperoxide reductase activity
MMHHMPGL_01579 2.3e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMHHMPGL_01580 3.3e-54 2.7.6.5 S guanosine tetraphosphate metabolic process
MMHHMPGL_01582 2.3e-105 K Transcriptional regulator
MMHHMPGL_01583 8.1e-131 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
MMHHMPGL_01584 1.8e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
MMHHMPGL_01585 3.5e-32 S Protein of unknown function (DUF1648)
MMHHMPGL_01586 9.8e-50 K Transcriptional regulator
MMHHMPGL_01587 7.5e-14
MMHHMPGL_01588 1.8e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MMHHMPGL_01589 7.1e-130 S Domain of unknown function (DUF4336)
MMHHMPGL_01590 8.8e-199 yeaN P transporter
MMHHMPGL_01591 2e-144 yitS S protein conserved in bacteria
MMHHMPGL_01592 1.7e-94 XK27_08140 K Bacterial regulatory proteins, tetR family
MMHHMPGL_01595 8.2e-22 S Domain of unknown function (DUF4767)
MMHHMPGL_01596 5.8e-152 S Domain of unknown function (DUF4300)
MMHHMPGL_01597 1.2e-127 V CAAX protease self-immunity
MMHHMPGL_01598 4.6e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MMHHMPGL_01599 2.9e-134 fecE 3.6.3.34 HP ABC transporter
MMHHMPGL_01600 5.9e-175 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MMHHMPGL_01601 3.4e-126 ybbA S Putative esterase
MMHHMPGL_01602 2.1e-46
MMHHMPGL_01603 5.5e-130 V CAAX protease self-immunity
MMHHMPGL_01604 9.8e-10
MMHHMPGL_01605 8.2e-22 M Bacterial lipoprotein
MMHHMPGL_01606 8.6e-66 S Protein of unknown function (DUF1722)
MMHHMPGL_01607 1.3e-63 yqeB S Pyrimidine dimer DNA glycosylase
MMHHMPGL_01609 3.4e-48
MMHHMPGL_01610 3.2e-94 S CAAX protease self-immunity
MMHHMPGL_01611 9.9e-93
MMHHMPGL_01612 1.8e-122 K sequence-specific DNA binding
MMHHMPGL_01613 1.5e-07
MMHHMPGL_01614 2.2e-140 ycgQ S TIGR03943 family
MMHHMPGL_01615 1.4e-156 XK27_03015 S permease
MMHHMPGL_01617 0.0 yhgF K Transcriptional accessory protein
MMHHMPGL_01618 9.3e-40 pspC KT PspC domain
MMHHMPGL_01619 2.8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MMHHMPGL_01620 2.1e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MMHHMPGL_01621 4.7e-11 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MMHHMPGL_01622 2.2e-65 ytxH S General stress protein
MMHHMPGL_01624 2.3e-178 yegQ O Peptidase U32
MMHHMPGL_01625 9.8e-252 yegQ O Peptidase U32
MMHHMPGL_01626 1.4e-90 bioY S biotin synthase
MMHHMPGL_01628 2.3e-33 XK27_12190 S protein conserved in bacteria
MMHHMPGL_01629 1.3e-225 mntH P H( )-stimulated, divalent metal cation uptake system
MMHHMPGL_01630 6.6e-208 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MMHHMPGL_01631 2.5e-153 mutH L DNA mismatch repair enzyme MutH
MMHHMPGL_01633 2e-08
MMHHMPGL_01634 4.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MMHHMPGL_01635 2.4e-144 M LysM domain
MMHHMPGL_01636 2.2e-23
MMHHMPGL_01637 2e-174 S hydrolase
MMHHMPGL_01640 1.1e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MMHHMPGL_01641 4.6e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MMHHMPGL_01642 9.1e-146 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MMHHMPGL_01643 2.5e-25 P Hemerythrin HHE cation binding domain protein
MMHHMPGL_01644 3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MMHHMPGL_01645 7.1e-209 MA20_36090 S Protein of unknown function (DUF2974)
MMHHMPGL_01646 2.5e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MMHHMPGL_01647 5.2e-46 S Phage derived protein Gp49-like (DUF891)
MMHHMPGL_01648 1.7e-45 K Helix-turn-helix domain
MMHHMPGL_01649 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
MMHHMPGL_01650 1.5e-270 hsdM 2.1.1.72 V N-6 DNA Methylase
MMHHMPGL_01651 4.7e-145 3.1.21.3 V Type I restriction modification DNA specificity domain
MMHHMPGL_01652 3.6e-112
MMHHMPGL_01654 3.3e-27 higA K Helix-turn-helix XRE-family like proteins
MMHHMPGL_01655 2e-155 S double-stranded DNA endodeoxyribonuclease activity
MMHHMPGL_01656 1.5e-07 S PD-(D/E)XK nuclease family transposase
MMHHMPGL_01657 0.0 M Right handed beta helix region
MMHHMPGL_01659 1e-91 lemA S LemA family
MMHHMPGL_01660 3.6e-136 htpX O Belongs to the peptidase M48B family
MMHHMPGL_01661 5.9e-120 sirR K iron dependent repressor
MMHHMPGL_01662 3.4e-169 sitA P Belongs to the bacterial solute-binding protein 9 family
MMHHMPGL_01663 2.2e-135 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
MMHHMPGL_01664 1.4e-130 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
MMHHMPGL_01665 3.7e-71 S Psort location CytoplasmicMembrane, score
MMHHMPGL_01666 4.4e-62 S Domain of unknown function (DUF4430)
MMHHMPGL_01667 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MMHHMPGL_01668 1.9e-185 holA 2.7.7.7 L DNA polymerase III delta subunit
MMHHMPGL_01669 1.2e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MMHHMPGL_01670 1.1e-166 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MMHHMPGL_01671 6.5e-111 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MMHHMPGL_01672 1.6e-54 bipA S protein secretion
MMHHMPGL_01674 0.0 M domain protein
MMHHMPGL_01675 7.2e-193 XK27_10075 S abc transporter atp-binding protein
MMHHMPGL_01678 0.0 V abc transporter atp-binding protein
MMHHMPGL_01679 1.6e-305 V abc transporter atp-binding protein
MMHHMPGL_01680 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MMHHMPGL_01682 2.7e-296 S Protein of unknown function (DUF3114)
MMHHMPGL_01683 6.2e-102 2.3.1.128 K Acetyltransferase GNAT Family
MMHHMPGL_01684 5.2e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
MMHHMPGL_01685 2.9e-151 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MMHHMPGL_01686 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MMHHMPGL_01687 5.2e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MMHHMPGL_01688 1.7e-194 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
MMHHMPGL_01689 3.4e-195 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MMHHMPGL_01690 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MMHHMPGL_01691 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MMHHMPGL_01692 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MMHHMPGL_01693 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MMHHMPGL_01694 1e-133 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MMHHMPGL_01695 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MMHHMPGL_01698 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MMHHMPGL_01699 2.2e-174 vraS 2.7.13.3 T Histidine kinase
MMHHMPGL_01700 1.8e-119 yvqF S Membrane
MMHHMPGL_01701 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MMHHMPGL_01702 6.2e-137 stp 3.1.3.16 T phosphatase
MMHHMPGL_01703 5.2e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MMHHMPGL_01704 5.6e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MMHHMPGL_01705 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MMHHMPGL_01706 4.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MMHHMPGL_01707 5.2e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MMHHMPGL_01708 1.8e-204 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MMHHMPGL_01709 1.3e-148 XK27_02985 S overlaps another CDS with the same product name
MMHHMPGL_01710 1.8e-142 supH S overlaps another CDS with the same product name
MMHHMPGL_01711 1.1e-62 yvoA_1 K Transcriptional
MMHHMPGL_01712 2.8e-120 skfE V abc transporter atp-binding protein
MMHHMPGL_01713 1.6e-111 V Psort location CytoplasmicMembrane, score
MMHHMPGL_01714 3.3e-172 oppF P Belongs to the ABC transporter superfamily
MMHHMPGL_01715 9.3e-203 oppD P Belongs to the ABC transporter superfamily
MMHHMPGL_01716 1.4e-167 amiD P ABC transporter (Permease
MMHHMPGL_01717 2.2e-279 amiC P ABC transporter (Permease
MMHHMPGL_01718 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MMHHMPGL_01719 6.5e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MMHHMPGL_01720 4.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MMHHMPGL_01721 6.1e-154 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MMHHMPGL_01722 1e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MMHHMPGL_01723 7.6e-103 yjbK S Adenylate cyclase
MMHHMPGL_01724 2.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMHHMPGL_01725 3.9e-204 iscS 2.8.1.7 E Cysteine desulfurase
MMHHMPGL_01726 3.1e-59 XK27_04120 S Putative amino acid metabolism
MMHHMPGL_01727 1.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MMHHMPGL_01728 9.7e-129 puuD T peptidase C26
MMHHMPGL_01729 1.1e-119 radC E Belongs to the UPF0758 family
MMHHMPGL_01730 1.6e-251 rgpF M Rhamnan synthesis protein F
MMHHMPGL_01731 9.3e-220 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MMHHMPGL_01732 6e-138 rgpC GM Transport permease protein
MMHHMPGL_01733 1.1e-167 rgpB GT2 M Glycosyltransferase, group 2 family protein
MMHHMPGL_01734 2.7e-216 rgpA GT4 M Domain of unknown function (DUF1972)
MMHHMPGL_01735 1.1e-207 GT4 M transferase activity, transferring glycosyl groups
MMHHMPGL_01736 1.4e-210 M Psort location CytoplasmicMembrane, score
MMHHMPGL_01737 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
MMHHMPGL_01738 1.8e-144 2.4.1.60 S Glycosyltransferase group 2 family protein
MMHHMPGL_01739 4.2e-43 S Uncharacterized conserved protein (DUF2304)
MMHHMPGL_01740 8.6e-125 arnC M group 2 family protein
MMHHMPGL_01741 2.1e-180 cpsIaJ S Glycosyltransferase like family 2
MMHHMPGL_01742 2.4e-157 S Glycosyltransferase like family 2
MMHHMPGL_01743 5.9e-209 amrA S membrane protein involved in the export of O-antigen and teichoic acid
MMHHMPGL_01744 2.2e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MMHHMPGL_01745 7.1e-246 S Glucosyl transferase GtrII
MMHHMPGL_01746 4.7e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MMHHMPGL_01747 5.9e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MMHHMPGL_01748 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MMHHMPGL_01749 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MMHHMPGL_01750 2.5e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MMHHMPGL_01751 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MMHHMPGL_01752 5.9e-138 gltS ET Belongs to the bacterial solute-binding protein 3 family
MMHHMPGL_01753 5.9e-213 arcT 2.6.1.1 E Aminotransferase
MMHHMPGL_01754 2.1e-135 ET Belongs to the bacterial solute-binding protein 3 family
MMHHMPGL_01755 9.3e-139 ET ABC transporter
MMHHMPGL_01756 9.2e-83 mutT 3.6.1.55 F Nudix family
MMHHMPGL_01757 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MMHHMPGL_01759 1.4e-162 S CAAX amino terminal protease family protein
MMHHMPGL_01760 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MMHHMPGL_01761 5.1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01762 1.7e-17 XK27_00735
MMHHMPGL_01763 3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MMHHMPGL_01765 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMHHMPGL_01766 1.8e-08 O ADP-ribosylglycohydrolase
MMHHMPGL_01767 4.2e-65 paaI Q protein possibly involved in aromatic compounds catabolism
MMHHMPGL_01768 7e-54 ycaO O OsmC-like protein
MMHHMPGL_01771 2e-35
MMHHMPGL_01773 2.4e-217 mutY L A G-specific adenine glycosylase
MMHHMPGL_01776 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MMHHMPGL_01777 1.1e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MMHHMPGL_01778 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MMHHMPGL_01780 5.9e-123 XK27_01040 S Protein of unknown function (DUF1129)
MMHHMPGL_01781 5e-168 corA P COG0598 Mg2 and Co2 transporters
MMHHMPGL_01782 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MMHHMPGL_01785 6.8e-31 blpT
MMHHMPGL_01786 1.6e-122 V 'abc transporter, ATP-binding protein
MMHHMPGL_01788 1.3e-188 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MMHHMPGL_01789 5.6e-85 comEB 3.5.4.12 F ComE operon protein 2
MMHHMPGL_01790 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMHHMPGL_01791 1.3e-61 yqhY S protein conserved in bacteria
MMHHMPGL_01792 8.3e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MMHHMPGL_01793 1.1e-170 scrR K Transcriptional regulator
MMHHMPGL_01794 3.8e-284 scrB 3.2.1.26 GH32 G invertase
MMHHMPGL_01795 0.0 scrA 2.7.1.211 G pts system
MMHHMPGL_01796 5.9e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MMHHMPGL_01798 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MMHHMPGL_01799 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MMHHMPGL_01800 8.2e-193 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MMHHMPGL_01801 1.1e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MMHHMPGL_01802 7e-198 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MMHHMPGL_01803 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MMHHMPGL_01807 1.9e-30 yozG K Transcriptional regulator
MMHHMPGL_01809 1.2e-171 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MMHHMPGL_01810 2.1e-260 XK27_03190 S hydrolases of the HAD superfamily
MMHHMPGL_01811 1.4e-108 yebC M Membrane
MMHHMPGL_01812 3.4e-308 KT response to antibiotic
MMHHMPGL_01813 1.6e-71 XK27_02470 K LytTr DNA-binding domain protein
MMHHMPGL_01814 4.4e-121 liaI S membrane
MMHHMPGL_01815 1.1e-297 O MreB/Mbl protein
MMHHMPGL_01817 1.9e-144 V Psort location CytoplasmicMembrane, score
MMHHMPGL_01820 2.6e-13
MMHHMPGL_01821 9.1e-237 hpk9 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_01822 6.6e-246 2.7.13.3 T protein histidine kinase activity
MMHHMPGL_01823 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MMHHMPGL_01824 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MMHHMPGL_01825 2.1e-126 S Protein of unknown function (DUF554)
MMHHMPGL_01826 2.8e-134 ecsA_2 V abc transporter atp-binding protein
MMHHMPGL_01827 1.2e-286 XK27_00765
MMHHMPGL_01828 3e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MMHHMPGL_01829 2.4e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MMHHMPGL_01830 9.2e-68 yhaI J Membrane
MMHHMPGL_01831 3.6e-67 yhaI J Protein of unknown function (DUF805)
MMHHMPGL_01833 2.4e-100
MMHHMPGL_01834 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MMHHMPGL_01835 4e-45 ftsL D cell division protein FtsL
MMHHMPGL_01836 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MMHHMPGL_01837 5.3e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MMHHMPGL_01838 2.1e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MMHHMPGL_01839 4.6e-55 S the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_01840 4.5e-55 cadC K Bacterial regulatory protein, arsR family
MMHHMPGL_01841 1.2e-98 cadD P Cadmium resistance transporter
MMHHMPGL_01843 4.8e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MMHHMPGL_01844 3e-80 yutD J protein conserved in bacteria
MMHHMPGL_01845 9.6e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MMHHMPGL_01846 1.4e-90 XK27_09885 V Glycopeptide antibiotics resistance protein
MMHHMPGL_01848 0.0 mdlA V abc transporter atp-binding protein
MMHHMPGL_01849 0.0 mdlB V abc transporter atp-binding protein
MMHHMPGL_01860 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MMHHMPGL_01861 9.2e-161 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MMHHMPGL_01862 1.4e-94 V CAAX protease self-immunity
MMHHMPGL_01863 1.7e-139 cppA E CppA N-terminal
MMHHMPGL_01864 1e-173 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MMHHMPGL_01866 4e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MMHHMPGL_01867 3.7e-145 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MMHHMPGL_01868 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MMHHMPGL_01869 1e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMHHMPGL_01870 2.1e-35
MMHHMPGL_01871 0.0 essC D DNA segregation ATPase FtsK SpoIIIE and related proteins
MMHHMPGL_01872 6.2e-35
MMHHMPGL_01873 6.1e-50
MMHHMPGL_01876 5.1e-26
MMHHMPGL_01877 2.8e-45
MMHHMPGL_01878 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MMHHMPGL_01879 1.4e-162 yxeN P ABC transporter (Permease
MMHHMPGL_01880 1.9e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
MMHHMPGL_01881 8.6e-10 S Protein of unknown function (DUF4059)
MMHHMPGL_01882 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MMHHMPGL_01883 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
MMHHMPGL_01884 5.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MMHHMPGL_01885 6e-194 ylbL T Belongs to the peptidase S16 family
MMHHMPGL_01886 3.7e-182 yhcC S radical SAM protein
MMHHMPGL_01887 1.7e-96 ytqB J (SAM)-dependent
MMHHMPGL_01889 0.0 yjcE P NhaP-type Na H and K H antiporters
MMHHMPGL_01890 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MMHHMPGL_01891 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MMHHMPGL_01892 1.4e-176 XK27_08075 M glycosyl transferase family 2
MMHHMPGL_01893 8e-81 S Carbohydrate-binding domain-containing protein Cthe_2159
MMHHMPGL_01894 1.8e-144 P molecular chaperone
MMHHMPGL_01895 2.9e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
MMHHMPGL_01896 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MMHHMPGL_01897 2.3e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MMHHMPGL_01898 3.6e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MMHHMPGL_01899 1e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MMHHMPGL_01900 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MMHHMPGL_01901 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MMHHMPGL_01902 3.6e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MMHHMPGL_01903 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MMHHMPGL_01904 4.2e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MMHHMPGL_01905 1.4e-187 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MMHHMPGL_01906 1.1e-57 XK27_08085
MMHHMPGL_01907 8.9e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MMHHMPGL_01908 4.8e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MMHHMPGL_01909 1.5e-112 ylfI S tigr01906
MMHHMPGL_01910 1.5e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MMHHMPGL_01911 3.8e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
MMHHMPGL_01912 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MMHHMPGL_01913 1.1e-29 KT response to antibiotic
MMHHMPGL_01915 4.3e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MMHHMPGL_01916 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MMHHMPGL_01917 1.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MMHHMPGL_01918 1.2e-247 S phospholipase Carboxylesterase
MMHHMPGL_01919 1.7e-196 yurR 1.4.5.1 E oxidoreductase
MMHHMPGL_01920 1e-140 zupT P Mediates zinc uptake. May also transport other divalent cations
MMHHMPGL_01921 6.4e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MMHHMPGL_01922 6.9e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
MMHHMPGL_01923 2.2e-62 gtrA S GtrA-like protein
MMHHMPGL_01924 9.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MMHHMPGL_01925 2.4e-165 ybbR S Protein conserved in bacteria
MMHHMPGL_01926 9.4e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MMHHMPGL_01927 2.3e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MMHHMPGL_01928 1.1e-149 cobQ S glutamine amidotransferase
MMHHMPGL_01929 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MMHHMPGL_01930 8.2e-131 pip 1.11.1.10 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MMHHMPGL_01931 2e-39 MA20_06245 S yiaA/B two helix domain
MMHHMPGL_01932 0.0 uup S abc transporter atp-binding protein
MMHHMPGL_01933 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MMHHMPGL_01934 4.3e-176 yfmL L DEAD DEAH box helicase
MMHHMPGL_01935 2.9e-226 XK27_05680 6.3.2.4 M carbamoylphosphate synthase large subunit
MMHHMPGL_01936 3.5e-153 XK27_05675 S Esterase
MMHHMPGL_01937 1.5e-160 XK27_05670 S Putative esterase
MMHHMPGL_01938 9.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MMHHMPGL_01939 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MMHHMPGL_01940 3e-38 ptsH G phosphocarrier protein Hpr
MMHHMPGL_01941 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
MMHHMPGL_01942 3.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
MMHHMPGL_01943 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MMHHMPGL_01944 1.3e-34 nrdH O Glutaredoxin
MMHHMPGL_01945 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMHHMPGL_01946 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMHHMPGL_01947 1.1e-234 L Transposase
MMHHMPGL_01948 1e-85
MMHHMPGL_01949 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MMHHMPGL_01950 3.8e-244 rodA D Belongs to the SEDS family
MMHHMPGL_01951 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MMHHMPGL_01952 7.4e-115 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MMHHMPGL_01953 1.3e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MMHHMPGL_01954 7.9e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MMHHMPGL_01955 1.7e-69 GnaT 2.5.1.16 K acetyltransferase
MMHHMPGL_01956 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MMHHMPGL_01958 2.6e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMHHMPGL_01959 5.4e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MMHHMPGL_01960 1.8e-122 dnaD
MMHHMPGL_01961 2.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MMHHMPGL_01963 4.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMHHMPGL_01964 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMHHMPGL_01965 5.8e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MMHHMPGL_01966 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MMHHMPGL_01967 8.3e-73 argR K Regulates arginine biosynthesis genes
MMHHMPGL_01968 1.1e-303 recN L May be involved in recombinational repair of damaged DNA
MMHHMPGL_01969 2.5e-147 DegV S DegV family
MMHHMPGL_01970 3.8e-146 ypmR E GDSL-like Lipase/Acylhydrolase
MMHHMPGL_01971 5.8e-95 ypmS S Protein conserved in bacteria
MMHHMPGL_01972 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMHHMPGL_01974 5.2e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MMHHMPGL_01975 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMHHMPGL_01976 8.2e-285 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MMHHMPGL_01977 4.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MMHHMPGL_01978 3e-44 ysdA L Membrane
MMHHMPGL_01979 7.3e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MMHHMPGL_01980 4.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MMHHMPGL_01981 0.0 dnaE 2.7.7.7 L DNA polymerase
MMHHMPGL_01982 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MMHHMPGL_01983 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MMHHMPGL_01984 9.4e-16 Q the current gene model (or a revised gene model) may contain a frame shift
MMHHMPGL_01985 9.4e-104 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MMHHMPGL_01986 6.1e-137 agrA KT phosphorelay signal transduction system
MMHHMPGL_01988 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
MMHHMPGL_01989 6e-143 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MMHHMPGL_01990 3.2e-225 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MMHHMPGL_01991 5.7e-186 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MMHHMPGL_01992 6.4e-221 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MMHHMPGL_01993 4.6e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MMHHMPGL_01994 8.8e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MMHHMPGL_01995 1.8e-151 yxkH G deacetylase
MMHHMPGL_01996 4.4e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MMHHMPGL_01997 7.7e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MMHHMPGL_01998 1.7e-149 rarD S Transporter
MMHHMPGL_01999 2.2e-15 T peptidase
MMHHMPGL_02000 1.2e-13
MMHHMPGL_02001 6.4e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MMHHMPGL_02002 5.1e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
MMHHMPGL_02003 7.4e-40
MMHHMPGL_02004 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MMHHMPGL_02005 2.7e-178 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MMHHMPGL_02006 5.6e-224 L AAA ATPase domain
MMHHMPGL_02007 2.5e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMHHMPGL_02008 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
MMHHMPGL_02009 4.3e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MMHHMPGL_02010 2.1e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMHHMPGL_02011 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MMHHMPGL_02012 1.6e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MMHHMPGL_02013 1e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MMHHMPGL_02014 2e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MMHHMPGL_02015 2.2e-227 ftsW D Belongs to the SEDS family
MMHHMPGL_02016 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MMHHMPGL_02017 1.2e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MMHHMPGL_02018 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MMHHMPGL_02020 8.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MMHHMPGL_02021 4e-156 holB 2.7.7.7 L dna polymerase iii
MMHHMPGL_02022 6.3e-138 yaaT S stage 0 sporulation protein
MMHHMPGL_02023 1.2e-54 yabA L Involved in initiation control of chromosome replication
MMHHMPGL_02024 2.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MMHHMPGL_02025 8.6e-229 amt P Ammonium Transporter
MMHHMPGL_02026 1.9e-53 glnB K Belongs to the P(II) protein family
MMHHMPGL_02027 6.6e-103 mur1 NU mannosyl-glycoprotein
MMHHMPGL_02028 1.4e-147 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MMHHMPGL_02029 8.2e-77 S Bacterial inner membrane protein
MMHHMPGL_02030 3.2e-292 nptA P COG1283 Na phosphate symporter
MMHHMPGL_02031 7.8e-216 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MMHHMPGL_02032 1.5e-220 S membrane
MMHHMPGL_02033 1.4e-65 S Glutathione-dependent formaldehyde-activating
MMHHMPGL_02034 3.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MMHHMPGL_02036 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MMHHMPGL_02037 2.6e-39 ynzC S UPF0291 protein
MMHHMPGL_02038 4.2e-256 cycA E permease
MMHHMPGL_02039 2e-08 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMHHMPGL_02040 6.8e-136 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MMHHMPGL_02043 1.1e-56
MMHHMPGL_02045 1.4e-67 K Helix-turn-helix
MMHHMPGL_02046 4.3e-42
MMHHMPGL_02048 9.9e-166 fhuR K transcriptional regulator (lysR family)
MMHHMPGL_02049 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MMHHMPGL_02050 8.6e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMHHMPGL_02051 8.1e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MMHHMPGL_02052 2.2e-227 pyrP F uracil Permease
MMHHMPGL_02053 1.7e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MMHHMPGL_02054 6.4e-212 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MMHHMPGL_02055 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MMHHMPGL_02056 3.6e-129 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
MMHHMPGL_02057 8.2e-195 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MMHHMPGL_02058 2.8e-123 macB V ABC transporter, ATP-binding protein
MMHHMPGL_02059 2.3e-202 V permease protein
MMHHMPGL_02060 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MMHHMPGL_02061 4.6e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MMHHMPGL_02064 1.5e-23 M Psort location Cytoplasmic, score
MMHHMPGL_02065 5.2e-67 K Psort location Cytoplasmic, score
MMHHMPGL_02066 1.3e-167 2.7.7.73, 2.7.7.80 H PFAM UBA THIF-type NAD FAD binding
MMHHMPGL_02067 8.3e-32
MMHHMPGL_02068 1.3e-109 V ABC transporter
MMHHMPGL_02069 3e-91 sagI S ABC-2 type transporter
MMHHMPGL_02070 4.2e-50 V ABC-type multidrug transport system ATPase component
MMHHMPGL_02071 5.8e-20
MMHHMPGL_02073 2.2e-310 mdlB V abc transporter atp-binding protein
MMHHMPGL_02074 4.2e-309 lmrA V abc transporter atp-binding protein
MMHHMPGL_02075 1.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MMHHMPGL_02076 2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MMHHMPGL_02077 1.8e-197 yceA S Belongs to the UPF0176 family
MMHHMPGL_02078 6.2e-112 S VIT family
MMHHMPGL_02079 5.9e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMHHMPGL_02080 5.7e-219 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MMHHMPGL_02083 1e-129 E alpha/beta hydrolase fold
MMHHMPGL_02084 3.3e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMHHMPGL_02085 4.2e-98 GBS0088 J protein conserved in bacteria
MMHHMPGL_02086 1.5e-155 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MMHHMPGL_02087 1.3e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MMHHMPGL_02088 2.6e-167 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MMHHMPGL_02089 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MMHHMPGL_02090 3.9e-148 V ABC transporter, ATP-binding protein
MMHHMPGL_02091 4e-53 S ABC-2 family transporter protein
MMHHMPGL_02092 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MMHHMPGL_02099 3e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
MMHHMPGL_02100 6.7e-103 S Domain of unknown function (DUF1803)
MMHHMPGL_02101 1e-101 ygaC J Belongs to the UPF0374 family
MMHHMPGL_02102 8.6e-134 recX 2.4.1.337 GT4 S Regulatory protein RecX
MMHHMPGL_02103 5e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMHHMPGL_02104 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
MMHHMPGL_02105 2.9e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
MMHHMPGL_02106 1.9e-115 S HAD hydrolase, family IA, variant 3
MMHHMPGL_02107 1.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MMHHMPGL_02108 1.5e-71 marR K Transcriptional regulator, MarR family
MMHHMPGL_02109 5.8e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMHHMPGL_02110 2.6e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMHHMPGL_02111 5.2e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MMHHMPGL_02112 5.2e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MMHHMPGL_02113 5.3e-125 IQ reductase
MMHHMPGL_02114 2.8e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MMHHMPGL_02115 9.9e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MMHHMPGL_02116 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MMHHMPGL_02117 2.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MMHHMPGL_02118 1.2e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MMHHMPGL_02119 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MMHHMPGL_02120 6.2e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MMHHMPGL_02121 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
MMHHMPGL_02122 1.8e-125 fruR K transcriptional
MMHHMPGL_02123 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MMHHMPGL_02124 0.0 fruA 2.7.1.202 G phosphotransferase system
MMHHMPGL_02125 5.1e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MMHHMPGL_02126 5.7e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MMHHMPGL_02128 2.8e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MMHHMPGL_02129 9.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMHHMPGL_02130 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MMHHMPGL_02131 2.5e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MMHHMPGL_02132 5.1e-93 2.3.1.128 K acetyltransferase
MMHHMPGL_02133 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MMHHMPGL_02134 9.6e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MMHHMPGL_02135 3.6e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMHHMPGL_02136 1.5e-62 WQ51_03320 S cog cog4835
MMHHMPGL_02137 2.1e-141 XK27_08360 S EDD domain protein, DegV family
MMHHMPGL_02138 4.6e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MMHHMPGL_02139 9.9e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MMHHMPGL_02140 0.0 yfmR S abc transporter atp-binding protein
MMHHMPGL_02141 5e-26 U response to pH
MMHHMPGL_02142 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
MMHHMPGL_02143 2.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MMHHMPGL_02144 4.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MMHHMPGL_02145 2.4e-295 S Psort location CytoplasmicMembrane, score
MMHHMPGL_02146 5.1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MMHHMPGL_02147 4.2e-77 K DNA-binding transcription factor activity
MMHHMPGL_02148 2.5e-311 lmrA1 V abc transporter atp-binding protein
MMHHMPGL_02149 0.0 lmrA2 V abc transporter atp-binding protein
MMHHMPGL_02150 8.7e-113 K Acetyltransferase (GNAT) family
MMHHMPGL_02151 3.6e-114 2.7.6.5 S Region found in RelA / SpoT proteins
MMHHMPGL_02152 3.3e-121 T response regulator
MMHHMPGL_02153 4.9e-208 sptS 2.7.13.3 T Histidine kinase
MMHHMPGL_02154 1.3e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MMHHMPGL_02155 2.2e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MMHHMPGL_02156 1.2e-160 cvfB S Protein conserved in bacteria
MMHHMPGL_02157 4.3e-35 yozE S Belongs to the UPF0346 family
MMHHMPGL_02158 3e-112 sip M LysM domain protein
MMHHMPGL_02159 3.2e-184 phoH T phosphate starvation-inducible protein PhoH
MMHHMPGL_02164 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMHHMPGL_02165 3.2e-146 mcrB V COG1401 GTPase subunit of restriction endonuclease
MMHHMPGL_02166 4.1e-181 mcrC V McrBC 5-methylcytosine restriction system component
MMHHMPGL_02167 6.4e-159 S reductase
MMHHMPGL_02168 3e-167 K transcriptional regulator (lysR family)
MMHHMPGL_02169 8.8e-128 S CAAX amino terminal protease family protein
MMHHMPGL_02170 4.5e-293 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MMHHMPGL_02171 1.5e-183 coiA 3.6.4.12 S Competence protein
MMHHMPGL_02172 0.0 pepF E oligoendopeptidase F
MMHHMPGL_02173 2.1e-126 yrrM 2.1.1.104 S O-Methyltransferase
MMHHMPGL_02174 5.4e-169 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MMHHMPGL_02175 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MMHHMPGL_02176 3.3e-156 K sequence-specific DNA binding
MMHHMPGL_02177 0.0 cbpD 3.5.1.28 NU GBS Bsp-like repeat
MMHHMPGL_02178 5.9e-09

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)