ORF_ID e_value Gene_name EC_number CAZy COGs Description
HELEIBLM_00001 1.1e-287 mphA S Aminoglycoside phosphotransferase
HELEIBLM_00002 1.2e-32 S Protein of unknown function (DUF3107)
HELEIBLM_00003 2.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HELEIBLM_00004 1.6e-126 S Vitamin K epoxide reductase
HELEIBLM_00005 1.2e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HELEIBLM_00006 7.9e-143 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HELEIBLM_00007 1.3e-156 S Patatin-like phospholipase
HELEIBLM_00008 3.7e-115 XK27_08050 O prohibitin homologues
HELEIBLM_00009 1.6e-109 E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00010 8.1e-143 tcyA ET Bacterial periplasmic substrate-binding proteins
HELEIBLM_00011 1.9e-138 3.6.3.21 E ATPases associated with a variety of cellular activities
HELEIBLM_00012 2.4e-242 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HELEIBLM_00013 2.2e-229 S Peptidase dimerisation domain
HELEIBLM_00014 0.0 E ATPases associated with a variety of cellular activities
HELEIBLM_00015 0.0 E Branched-chain amino acid transport system / permease component
HELEIBLM_00016 4.5e-219 E Receptor family ligand binding region
HELEIBLM_00017 5.4e-200 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
HELEIBLM_00018 3.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HELEIBLM_00019 3.8e-153 E Glyoxalase-like domain
HELEIBLM_00020 9.5e-42 XAC3035 O Glutaredoxin
HELEIBLM_00021 1.4e-223 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HELEIBLM_00022 3.1e-127 cjaA ET Bacterial periplasmic substrate-binding proteins
HELEIBLM_00023 4.1e-115 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HELEIBLM_00024 6.8e-111 glnP E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00025 6.4e-98 papP E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00026 5.9e-120 ypfH S Phospholipase/Carboxylesterase
HELEIBLM_00027 0.0 tetP J Elongation factor G, domain IV
HELEIBLM_00028 8.1e-131 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HELEIBLM_00030 7.8e-103 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HELEIBLM_00031 6.3e-168 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HELEIBLM_00032 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HELEIBLM_00033 1.2e-239 carA 6.3.5.5 F Belongs to the CarA family
HELEIBLM_00034 5.4e-77 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HELEIBLM_00035 4e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HELEIBLM_00036 6.3e-113 ybbL V ATPases associated with a variety of cellular activities
HELEIBLM_00037 8.6e-129 ybbM V Uncharacterised protein family (UPF0014)
HELEIBLM_00038 7.3e-270 T Diguanylate cyclase, GGDEF domain
HELEIBLM_00039 6.7e-99 L Transposase and inactivated derivatives IS30 family
HELEIBLM_00041 3.1e-83 2.7.11.1 S HipA-like C-terminal domain
HELEIBLM_00044 5.8e-99 L Psort location Cytoplasmic, score 8.87
HELEIBLM_00045 1.6e-80 S N-methyltransferase activity
HELEIBLM_00046 1.4e-79 int L Phage integrase, N-terminal SAM-like domain
HELEIBLM_00047 1.4e-36
HELEIBLM_00048 2.6e-129 pgp 3.1.3.18 S HAD-hyrolase-like
HELEIBLM_00049 1.1e-61 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HELEIBLM_00050 0.0 helY L DEAD DEAH box helicase
HELEIBLM_00051 2.3e-48
HELEIBLM_00052 0.0 pafB K WYL domain
HELEIBLM_00053 5e-295 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HELEIBLM_00055 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HELEIBLM_00056 6.5e-142 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HELEIBLM_00057 2.3e-160 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HELEIBLM_00058 2e-30
HELEIBLM_00060 1e-153 cbiO V ATPases associated with a variety of cellular activities
HELEIBLM_00061 1e-187 lanT 3.6.3.27 V ABC transporter
HELEIBLM_00062 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HELEIBLM_00063 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HELEIBLM_00064 1.3e-246 pbuO S Permease family
HELEIBLM_00065 3.6e-138 3.2.1.8 S alpha beta
HELEIBLM_00066 3.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HELEIBLM_00067 1.1e-33 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HELEIBLM_00068 2.4e-187 T Forkhead associated domain
HELEIBLM_00069 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HELEIBLM_00070 1.7e-30
HELEIBLM_00071 1.6e-93 flgA NO SAF
HELEIBLM_00072 2.5e-31 fmdB S Putative regulatory protein
HELEIBLM_00073 4.8e-118 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HELEIBLM_00074 1.1e-126 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HELEIBLM_00075 6.1e-186
HELEIBLM_00076 6.7e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HELEIBLM_00077 2.6e-40 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HELEIBLM_00081 4.1e-25 rpmG J Ribosomal protein L33
HELEIBLM_00082 2.1e-219 murB 1.3.1.98 M Cell wall formation
HELEIBLM_00083 4.4e-267 E aromatic amino acid transport protein AroP K03293
HELEIBLM_00084 1.7e-59 fdxA C 4Fe-4S binding domain
HELEIBLM_00085 2.7e-214 dapC E Aminotransferase class I and II
HELEIBLM_00086 2.1e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HELEIBLM_00089 8.7e-187 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HELEIBLM_00090 5.5e-110 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HELEIBLM_00091 4.9e-107
HELEIBLM_00092 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HELEIBLM_00093 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HELEIBLM_00094 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
HELEIBLM_00095 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HELEIBLM_00096 5.2e-223 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HELEIBLM_00097 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HELEIBLM_00098 1.6e-38 ywiC S YwiC-like protein
HELEIBLM_00099 4.5e-143 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HELEIBLM_00100 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
HELEIBLM_00101 1.1e-115 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HELEIBLM_00102 1.2e-115 rplD J Forms part of the polypeptide exit tunnel
HELEIBLM_00103 3.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HELEIBLM_00104 8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HELEIBLM_00105 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HELEIBLM_00106 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HELEIBLM_00107 2.4e-102 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HELEIBLM_00108 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HELEIBLM_00109 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
HELEIBLM_00110 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HELEIBLM_00111 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HELEIBLM_00112 1.8e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HELEIBLM_00113 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HELEIBLM_00114 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HELEIBLM_00115 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HELEIBLM_00116 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HELEIBLM_00117 2.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HELEIBLM_00118 1.5e-95 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HELEIBLM_00119 9.2e-26 rpmD J Ribosomal protein L30p/L7e
HELEIBLM_00120 1.1e-75 rplO J binds to the 23S rRNA
HELEIBLM_00121 7.6e-247 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HELEIBLM_00122 6.5e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HELEIBLM_00123 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HELEIBLM_00124 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HELEIBLM_00125 4.7e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HELEIBLM_00126 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HELEIBLM_00127 2e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELEIBLM_00128 1.7e-61 rplQ J Ribosomal protein L17
HELEIBLM_00129 2.6e-166 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HELEIBLM_00130 0.0 gcs2 S A circularly permuted ATPgrasp
HELEIBLM_00131 8.8e-150 E Transglutaminase/protease-like homologues
HELEIBLM_00132 6.1e-217 S Psort location Cytoplasmic, score
HELEIBLM_00134 2.6e-12 L Integrase core domain
HELEIBLM_00135 2.4e-159 P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00136 6.3e-174 P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00137 8.1e-244 G Bacterial extracellular solute-binding protein
HELEIBLM_00138 9.9e-124
HELEIBLM_00139 9.5e-184 nusA K Participates in both transcription termination and antitermination
HELEIBLM_00140 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HELEIBLM_00141 8.1e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HELEIBLM_00142 1.1e-209 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HELEIBLM_00143 2.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HELEIBLM_00144 4.7e-277 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HELEIBLM_00145 3.9e-92
HELEIBLM_00147 1.5e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HELEIBLM_00148 8.7e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HELEIBLM_00150 1.4e-274 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HELEIBLM_00151 2.9e-67 K Transcriptional regulator
HELEIBLM_00152 8.4e-185 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HELEIBLM_00153 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HELEIBLM_00154 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
HELEIBLM_00155 6.1e-160 arbG K CAT RNA binding domain
HELEIBLM_00156 1.7e-202 I Diacylglycerol kinase catalytic domain
HELEIBLM_00157 1.7e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HELEIBLM_00159 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HELEIBLM_00160 9.3e-187 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
HELEIBLM_00161 2.3e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HELEIBLM_00162 4.8e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HELEIBLM_00163 2.7e-110 degU K helix_turn_helix, Lux Regulon
HELEIBLM_00164 5.8e-225 tcsS3 KT PspC domain
HELEIBLM_00165 1.1e-165 pspC KT PspC domain
HELEIBLM_00166 3.9e-53
HELEIBLM_00167 2.1e-280 S alpha beta
HELEIBLM_00168 1.2e-112 S Protein of unknown function (DUF4125)
HELEIBLM_00169 8e-280 S Domain of unknown function (DUF4037)
HELEIBLM_00170 0.0 phoC 3.1.3.5 I PAP2 superfamily
HELEIBLM_00171 3.7e-205 araJ EGP Major facilitator Superfamily
HELEIBLM_00173 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HELEIBLM_00174 2.1e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HELEIBLM_00175 1.4e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HELEIBLM_00176 1.7e-114 phoU P Plays a role in the regulation of phosphate uptake
HELEIBLM_00177 1.5e-193 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELEIBLM_00178 4.3e-37
HELEIBLM_00179 8.8e-212 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HELEIBLM_00181 1.5e-167 usp 3.5.1.28 CBM50 S CHAP domain
HELEIBLM_00182 1.1e-78 M NlpC/P60 family
HELEIBLM_00183 4.4e-103 M NlpC/P60 family
HELEIBLM_00184 2.6e-186 T Universal stress protein family
HELEIBLM_00185 2e-73 attW O OsmC-like protein
HELEIBLM_00186 1.1e-172 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HELEIBLM_00187 4e-124 folA 1.5.1.3 H dihydrofolate reductase
HELEIBLM_00188 1.1e-97 ptpA 3.1.3.48 T low molecular weight
HELEIBLM_00189 2.4e-110 vex2 V ABC transporter, ATP-binding protein
HELEIBLM_00190 3e-210 vex1 V Efflux ABC transporter, permease protein
HELEIBLM_00191 3.4e-218 vex3 V ABC transporter permease
HELEIBLM_00192 5.5e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HELEIBLM_00193 5.5e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HELEIBLM_00194 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HELEIBLM_00195 2.4e-181 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HELEIBLM_00196 3.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HELEIBLM_00197 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HELEIBLM_00198 6.8e-125 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HELEIBLM_00199 1.5e-124 apl 3.1.3.1 S SNARE associated Golgi protein
HELEIBLM_00200 3.9e-287 arc O AAA ATPase forming ring-shaped complexes
HELEIBLM_00201 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HELEIBLM_00202 9.5e-169 hisN 3.1.3.25 G Inositol monophosphatase family
HELEIBLM_00204 1.2e-269 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HELEIBLM_00205 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HELEIBLM_00206 5.9e-10 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HELEIBLM_00207 3.5e-121 S AAA ATPase domain
HELEIBLM_00208 1.7e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HELEIBLM_00209 0.0 S Lysylphosphatidylglycerol synthase TM region
HELEIBLM_00210 6.2e-42 hup L Belongs to the bacterial histone-like protein family
HELEIBLM_00211 5.7e-32 L HTH-like domain
HELEIBLM_00213 3.9e-152 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_00214 1.6e-150 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_00215 3.3e-161 P Cation efflux family
HELEIBLM_00216 9.5e-300 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HELEIBLM_00217 1.1e-137 guaA1 6.3.5.2 F Peptidase C26
HELEIBLM_00218 0.0 yjjK S ABC transporter
HELEIBLM_00219 2.1e-62 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
HELEIBLM_00220 8.6e-44 stbC S Plasmid stability protein
HELEIBLM_00221 3.8e-91 ilvN 2.2.1.6 E ACT domain
HELEIBLM_00222 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HELEIBLM_00223 2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HELEIBLM_00224 7.6e-31 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HELEIBLM_00225 6.3e-119 yceD S Uncharacterized ACR, COG1399
HELEIBLM_00226 1.2e-120
HELEIBLM_00227 2.1e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HELEIBLM_00228 2e-51 S Protein of unknown function (DUF3039)
HELEIBLM_00229 9.6e-194 yghZ C Aldo/keto reductase family
HELEIBLM_00230 6.3e-70 soxR K MerR, DNA binding
HELEIBLM_00231 7.2e-115
HELEIBLM_00232 3.7e-246 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HELEIBLM_00233 4.6e-81 V ABC-2 family transporter protein
HELEIBLM_00234 1.1e-108 V ATPases associated with a variety of cellular activities
HELEIBLM_00235 4.1e-21 tnp7109-21 L Integrase core domain
HELEIBLM_00236 5.9e-27 tnp7109-21 L Integrase core domain
HELEIBLM_00237 9.3e-152 M Glycosyltransferase like family 2
HELEIBLM_00239 1.4e-223 glf 5.4.99.9 M UDP-galactopyranose mutase
HELEIBLM_00240 9.5e-114 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HELEIBLM_00241 2.8e-10 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HELEIBLM_00242 4.7e-41 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HELEIBLM_00243 4.8e-19 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HELEIBLM_00244 4.1e-86 K Periplasmic binding protein domain
HELEIBLM_00245 3e-77 F Inosine-uridine preferring nucleoside hydrolase
HELEIBLM_00246 1e-118 G Bacterial extracellular solute-binding protein
HELEIBLM_00247 7.1e-103 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_00248 1.4e-84 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_00249 5.6e-52 rbsK 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HELEIBLM_00250 7.8e-39 F Permease family
HELEIBLM_00251 7.3e-121 F Permease family
HELEIBLM_00252 4.3e-161 L HTH-like domain
HELEIBLM_00253 7.2e-155 yvgN 1.1.1.346 S Aldo/keto reductase family
HELEIBLM_00254 5e-268 2.7.1.17 GH19 G FGGY family of carbohydrate kinases, N-terminal domain
HELEIBLM_00255 2.7e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HELEIBLM_00256 5.2e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HELEIBLM_00257 1.8e-110 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HELEIBLM_00258 5e-97
HELEIBLM_00259 2e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HELEIBLM_00260 6.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HELEIBLM_00261 1.7e-19 S Uncharacterized protein conserved in bacteria (DUF2252)
HELEIBLM_00262 2.6e-263 glnA2 6.3.1.2 E glutamine synthetase
HELEIBLM_00263 6.8e-186 EGP Major facilitator Superfamily
HELEIBLM_00264 2.8e-131 appC EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_00265 4.7e-177 EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_00266 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
HELEIBLM_00267 5.1e-309 P Belongs to the ABC transporter superfamily
HELEIBLM_00268 3.5e-172 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HELEIBLM_00269 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HELEIBLM_00270 5.8e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HELEIBLM_00271 8.2e-274 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HELEIBLM_00272 3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HELEIBLM_00273 6.7e-157 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HELEIBLM_00274 6.6e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HELEIBLM_00275 1.3e-35 M Lysin motif
HELEIBLM_00276 5.3e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HELEIBLM_00277 4.9e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HELEIBLM_00278 0.0 L DNA helicase
HELEIBLM_00279 5.5e-92 mraZ K Belongs to the MraZ family
HELEIBLM_00280 2.7e-194 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HELEIBLM_00281 3.2e-72 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HELEIBLM_00282 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HELEIBLM_00283 7.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HELEIBLM_00284 1.2e-245 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HELEIBLM_00285 1.7e-204 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HELEIBLM_00286 7.1e-275 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HELEIBLM_00287 1.3e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HELEIBLM_00288 5.9e-219 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HELEIBLM_00289 9.5e-286 murC 6.3.2.8 M Belongs to the MurCDEF family
HELEIBLM_00290 2.8e-183 ftsQ 6.3.2.4 D Cell division protein FtsQ
HELEIBLM_00291 4.1e-15
HELEIBLM_00292 3.9e-248 3.2.1.14 GH18 S Carbohydrate binding domain
HELEIBLM_00293 0.0 M probably involved in cell wall
HELEIBLM_00294 5e-121 S Membrane transport protein
HELEIBLM_00295 1.3e-32 ybbL V ATPases associated with a variety of cellular activities
HELEIBLM_00296 2.3e-82 ybbM V Uncharacterised protein family (UPF0014)
HELEIBLM_00297 0.0 G Glycosyl hydrolase family 20, domain 2
HELEIBLM_00298 6.2e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HELEIBLM_00299 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HELEIBLM_00300 0.0 S Tetratricopeptide repeat
HELEIBLM_00301 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HELEIBLM_00302 9.4e-139 bioM P ATPases associated with a variety of cellular activities
HELEIBLM_00303 2.5e-231 E Aminotransferase class I and II
HELEIBLM_00304 4.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HELEIBLM_00305 1.8e-200 S Glycosyltransferase, group 2 family protein
HELEIBLM_00306 1.9e-102 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HELEIBLM_00307 0.0 ecfA GP ABC transporter, ATP-binding protein
HELEIBLM_00308 9.1e-47 yhbY J CRS1_YhbY
HELEIBLM_00309 5.4e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HELEIBLM_00310 6.5e-53 J TM2 domain
HELEIBLM_00311 1.2e-185 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HELEIBLM_00312 3.4e-248 EGP Major facilitator Superfamily
HELEIBLM_00313 3e-246 rarA L Recombination factor protein RarA
HELEIBLM_00314 0.0 L DEAD DEAH box helicase
HELEIBLM_00315 5.1e-177 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HELEIBLM_00316 4e-284 phoN I PAP2 superfamily
HELEIBLM_00317 1.2e-184 gluD E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00318 3.9e-106 gluC E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00319 4.4e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
HELEIBLM_00320 1e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HELEIBLM_00321 7.9e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
HELEIBLM_00323 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HELEIBLM_00324 5.7e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HELEIBLM_00325 2.1e-210 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HELEIBLM_00326 5.6e-306 3.1.3.5 F 5'-nucleotidase, C-terminal domain
HELEIBLM_00327 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HELEIBLM_00328 1.6e-177 uspA T Belongs to the universal stress protein A family
HELEIBLM_00329 6e-163 S Protein of unknown function (DUF3027)
HELEIBLM_00330 6.5e-66 cspB K 'Cold-shock' DNA-binding domain
HELEIBLM_00331 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELEIBLM_00332 5.6e-133 KT Response regulator receiver domain protein
HELEIBLM_00333 8.6e-66
HELEIBLM_00334 1.7e-34 S Proteins of 100 residues with WXG
HELEIBLM_00335 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HELEIBLM_00336 1.4e-37 K 'Cold-shock' DNA-binding domain
HELEIBLM_00337 3.1e-71 S LytR cell envelope-related transcriptional attenuator
HELEIBLM_00338 6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HELEIBLM_00339 3.3e-192 moxR S ATPase family associated with various cellular activities (AAA)
HELEIBLM_00340 3.1e-170 S Protein of unknown function DUF58
HELEIBLM_00341 1.1e-90
HELEIBLM_00342 6.1e-183 S von Willebrand factor (vWF) type A domain
HELEIBLM_00343 1.8e-163 S von Willebrand factor (vWF) type A domain
HELEIBLM_00344 3.5e-45
HELEIBLM_00345 5.5e-48
HELEIBLM_00346 5.6e-305 S PGAP1-like protein
HELEIBLM_00347 6.2e-13
HELEIBLM_00348 1e-108 ykoE S ABC-type cobalt transport system, permease component
HELEIBLM_00349 3.4e-208 K helix_turn _helix lactose operon repressor
HELEIBLM_00350 1.5e-147 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HELEIBLM_00351 1.5e-139 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HELEIBLM_00352 1.1e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HELEIBLM_00353 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00354 4.3e-256 abcT3 P ATPases associated with a variety of cellular activities
HELEIBLM_00355 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HELEIBLM_00358 5.8e-167 S Auxin Efflux Carrier
HELEIBLM_00359 2e-113 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HELEIBLM_00360 9.1e-95 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HELEIBLM_00361 2.2e-235 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HELEIBLM_00363 1.9e-130 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HELEIBLM_00364 4.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HELEIBLM_00365 3.4e-160
HELEIBLM_00366 7.1e-50 thiF 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HELEIBLM_00367 3.9e-240 EGP Major facilitator Superfamily
HELEIBLM_00368 2.9e-34 D Filamentation induced by cAMP protein fic
HELEIBLM_00369 1.3e-202 L Transposase, Mutator family
HELEIBLM_00370 8.6e-11 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HELEIBLM_00372 3.3e-26
HELEIBLM_00373 2.1e-140 fic D Fic/DOC family
HELEIBLM_00374 1.5e-52 L Phage integrase family
HELEIBLM_00375 3e-150 L Phage integrase family
HELEIBLM_00376 1.7e-184 V Abi-like protein
HELEIBLM_00377 1.3e-14 V Abi-like protein
HELEIBLM_00380 3.9e-43 yxaM EGP Major Facilitator Superfamily
HELEIBLM_00381 2.6e-12 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HELEIBLM_00382 4.7e-09 L Transposase
HELEIBLM_00383 2.1e-206 K Transposase IS116 IS110 IS902
HELEIBLM_00384 4.4e-113 L IstB-like ATP binding protein
HELEIBLM_00385 2.2e-123 L PFAM Integrase catalytic
HELEIBLM_00386 2.2e-11 S EamA-like transporter family
HELEIBLM_00387 6.8e-43
HELEIBLM_00388 0.0 E Sodium:solute symporter family
HELEIBLM_00389 2.5e-47 lacS G Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_00390 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HELEIBLM_00391 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
HELEIBLM_00392 1.3e-255 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
HELEIBLM_00393 4.2e-69 fucU 5.1.3.29 G RbsD / FucU transport protein family
HELEIBLM_00394 4.7e-152 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HELEIBLM_00395 1.5e-141 IQ KR domain
HELEIBLM_00396 1.8e-242 4.2.1.68 M Enolase C-terminal domain-like
HELEIBLM_00397 1.3e-95 S Protein of unknown function, DUF624
HELEIBLM_00398 1.7e-81 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HELEIBLM_00399 6.5e-22 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HELEIBLM_00400 7.3e-74 uhpT EGP Major facilitator Superfamily
HELEIBLM_00401 5e-94 L HTH-like domain
HELEIBLM_00402 2.3e-31 L HTH-like domain
HELEIBLM_00403 1.5e-59 K Virulence activator alpha C-term
HELEIBLM_00404 5.9e-263 V FtsX-like permease family
HELEIBLM_00405 1.5e-94 V ATPases associated with a variety of cellular activities
HELEIBLM_00406 1.2e-29
HELEIBLM_00407 2.6e-17 L Transposase, Mutator family
HELEIBLM_00408 2.3e-85
HELEIBLM_00409 6.6e-21
HELEIBLM_00410 6.8e-60 L Transposase and inactivated derivatives IS30 family
HELEIBLM_00411 3.5e-114 S Psort location CytoplasmicMembrane, score 9.99
HELEIBLM_00412 1.3e-108 3.1.3.48 T Low molecular weight phosphatase family
HELEIBLM_00413 2.5e-234 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HELEIBLM_00416 4.9e-45 ytrE_1 3.6.3.21 V ABC transporter
HELEIBLM_00417 6.1e-22 V efflux transmembrane transporter activity
HELEIBLM_00418 2.1e-55
HELEIBLM_00419 5.8e-112 K helix_turn_helix, mercury resistance
HELEIBLM_00420 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
HELEIBLM_00421 2.1e-138 S Bacterial protein of unknown function (DUF881)
HELEIBLM_00422 1.2e-28 sbp S Protein of unknown function (DUF1290)
HELEIBLM_00423 1.6e-124 S Bacterial protein of unknown function (DUF881)
HELEIBLM_00424 6e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HELEIBLM_00425 2.1e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HELEIBLM_00426 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HELEIBLM_00427 2.3e-103 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HELEIBLM_00428 1.2e-185 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HELEIBLM_00429 3.9e-159 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HELEIBLM_00430 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HELEIBLM_00431 5.5e-132 S SOS response associated peptidase (SRAP)
HELEIBLM_00432 4.3e-155 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HELEIBLM_00433 9.7e-253 mmuP E amino acid
HELEIBLM_00434 4.2e-80 EGP Major facilitator Superfamily
HELEIBLM_00435 1.1e-189 V VanZ like family
HELEIBLM_00436 4e-14 cefD 5.1.1.17 E Aminotransferase, class V
HELEIBLM_00437 6.5e-19 cefD 5.1.1.17 E Aminotransferase, class V
HELEIBLM_00438 4.2e-56 S EamA-like transporter family
HELEIBLM_00439 1.6e-206 L Transposase
HELEIBLM_00440 4.6e-88
HELEIBLM_00441 3.8e-170 V MacB-like periplasmic core domain
HELEIBLM_00442 5e-128 V ATPases associated with a variety of cellular activities
HELEIBLM_00443 1.3e-119 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELEIBLM_00444 2e-30 EGP Major Facilitator Superfamily
HELEIBLM_00445 4.9e-22 K trisaccharide binding
HELEIBLM_00446 4.9e-109 K COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELEIBLM_00447 3.5e-117 T PhoQ Sensor
HELEIBLM_00448 1.2e-110 V ABC transporter
HELEIBLM_00449 2.8e-276 V FtsX-like permease family
HELEIBLM_00450 9.3e-27 K Psort location Cytoplasmic, score
HELEIBLM_00453 7.2e-190 3.6.4.12 K Divergent AAA domain protein
HELEIBLM_00454 2e-120 V ATPases associated with a variety of cellular activities
HELEIBLM_00455 2.2e-99
HELEIBLM_00456 4.4e-80
HELEIBLM_00458 5.9e-17 spaB S Lantibiotic biosynthesis dehydratase C-term
HELEIBLM_00459 3.2e-18 V Lanthionine synthetase C-like protein
HELEIBLM_00460 9.6e-41 V ATPase activity
HELEIBLM_00461 1.6e-43 V ABC-2 type transporter
HELEIBLM_00462 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
HELEIBLM_00463 1.3e-271 S Psort location Cytoplasmic, score
HELEIBLM_00464 5.5e-125
HELEIBLM_00466 4.8e-25
HELEIBLM_00467 3e-69
HELEIBLM_00468 1.7e-35
HELEIBLM_00469 2.3e-102 parA D AAA domain
HELEIBLM_00470 8e-83 S Transcription factor WhiB
HELEIBLM_00471 4.3e-233 S Helix-turn-helix domain
HELEIBLM_00472 2.2e-21
HELEIBLM_00473 2.6e-11
HELEIBLM_00475 1.1e-158 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HELEIBLM_00476 2.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HELEIBLM_00478 7.9e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HELEIBLM_00479 4.9e-202 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HELEIBLM_00480 1.5e-177 3.4.14.13 M Glycosyltransferase like family 2
HELEIBLM_00481 4.8e-267 S AI-2E family transporter
HELEIBLM_00482 8.2e-232 epsG M Glycosyl transferase family 21
HELEIBLM_00483 6.1e-147 natA V ATPases associated with a variety of cellular activities
HELEIBLM_00484 1.1e-300
HELEIBLM_00485 4.5e-256 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HELEIBLM_00486 1.1e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HELEIBLM_00487 1.4e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HELEIBLM_00488 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HELEIBLM_00490 5.8e-106 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HELEIBLM_00491 2.5e-158 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HELEIBLM_00492 2.1e-263 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HELEIBLM_00493 7.2e-92 S Protein of unknown function (DUF3180)
HELEIBLM_00494 4.3e-169 tesB I Thioesterase-like superfamily
HELEIBLM_00495 0.0 yjjK S ATP-binding cassette protein, ChvD family
HELEIBLM_00496 1.1e-09 L Transposase, Mutator family
HELEIBLM_00497 4.4e-206 EGP Major facilitator Superfamily
HELEIBLM_00498 6.9e-72 C Domain of unknown function (DUF4365)
HELEIBLM_00499 5.8e-165 res 3.1.21.5 V Type III restriction enzyme, res subunit
HELEIBLM_00501 5.8e-97 K Helix-turn-helix domain protein
HELEIBLM_00503 1.6e-99 S Acetyltransferase (GNAT) domain
HELEIBLM_00504 5.4e-36 S Uncharacterized protein conserved in bacteria (DUF2316)
HELEIBLM_00505 1.3e-90 MA20_25245 K FR47-like protein
HELEIBLM_00506 6.2e-46 L Transposase
HELEIBLM_00507 3.6e-194
HELEIBLM_00508 1e-133 ytrE V ABC transporter
HELEIBLM_00509 2.2e-188 V Putative peptidoglycan binding domain
HELEIBLM_00510 1.1e-119
HELEIBLM_00511 2.9e-48
HELEIBLM_00512 4.6e-120 K Transcriptional regulatory protein, C terminal
HELEIBLM_00513 3.9e-232 qseC 2.7.13.3 T GHKL domain
HELEIBLM_00514 3.5e-97 K transcriptional regulator
HELEIBLM_00515 6.4e-37
HELEIBLM_00516 4.4e-29
HELEIBLM_00517 7.6e-144
HELEIBLM_00518 1.1e-65 S PrgI family protein
HELEIBLM_00519 2.1e-131 trsE U type IV secretory pathway VirB4
HELEIBLM_00520 4.3e-24
HELEIBLM_00522 7.5e-124 V ABC transporter
HELEIBLM_00525 2e-26 U Type IV secretory system Conjugative DNA transfer
HELEIBLM_00526 1.7e-230 T Histidine kinase
HELEIBLM_00527 1.1e-122 K helix_turn_helix, Lux Regulon
HELEIBLM_00528 7.3e-121 V ABC transporter
HELEIBLM_00529 1.4e-17
HELEIBLM_00530 8.9e-93 E Asparagine synthase
HELEIBLM_00531 1.6e-138 V ABC transporter
HELEIBLM_00532 1.8e-222 V Efflux ABC transporter, permease protein
HELEIBLM_00533 2.3e-66
HELEIBLM_00534 5.2e-41
HELEIBLM_00535 1.4e-194 T Histidine kinase
HELEIBLM_00536 1.9e-116 K Bacterial regulatory proteins, luxR family
HELEIBLM_00537 1.2e-116 V VanZ like family
HELEIBLM_00538 5.3e-96 rpoE4 K Sigma-70 region 2
HELEIBLM_00539 1.1e-22 S Psort location CytoplasmicMembrane, score
HELEIBLM_00540 2.1e-106
HELEIBLM_00541 1.4e-136
HELEIBLM_00542 2.4e-169 yfiL V ATPases associated with a variety of cellular activities
HELEIBLM_00543 1.1e-65
HELEIBLM_00544 1.1e-140 G Glycosyl hydrolase family 20, domain 2
HELEIBLM_00545 5.3e-68 G Glycosyl hydrolase family 20, domain 2
HELEIBLM_00546 1e-33 G Glycosyl hydrolase family 20, domain 2
HELEIBLM_00547 4.4e-244 L Phage integrase family
HELEIBLM_00549 3.6e-20 S Protein of unknown function (DUF2599)
HELEIBLM_00550 2.5e-127
HELEIBLM_00551 5.6e-78
HELEIBLM_00552 1.7e-211 L Phage integrase family
HELEIBLM_00553 2.6e-139 M Psort location Cytoplasmic, score 8.87
HELEIBLM_00554 3e-52 GT4 M Psort location Cytoplasmic, score 8.87
HELEIBLM_00555 2e-07
HELEIBLM_00556 8.9e-63 C Polysaccharide pyruvyl transferase
HELEIBLM_00557 2.9e-119 S Psort location CytoplasmicMembrane, score 9.99
HELEIBLM_00558 1.3e-46 M Glycosyltransferase like family 2
HELEIBLM_00559 1.3e-177 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HELEIBLM_00560 6e-20 L Phage integrase family
HELEIBLM_00561 1e-167 L Phage integrase, N-terminal SAM-like domain
HELEIBLM_00562 4.9e-47 insK L Integrase core domain
HELEIBLM_00563 2e-62 tyrA 5.4.99.5 E Chorismate mutase type II
HELEIBLM_00564 1.2e-296 S domain protein
HELEIBLM_00565 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HELEIBLM_00566 1.2e-283 E Bacterial extracellular solute-binding proteins, family 5 Middle
HELEIBLM_00567 1.5e-129 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HELEIBLM_00568 3.7e-132 KT Transcriptional regulatory protein, C terminal
HELEIBLM_00569 1.2e-78
HELEIBLM_00570 4.8e-97 mntP P Probably functions as a manganese efflux pump
HELEIBLM_00571 2.8e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HELEIBLM_00572 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HELEIBLM_00573 0.0 K RNA polymerase II activating transcription factor binding
HELEIBLM_00574 8e-75 S Psort location Cytoplasmic, score 8.87
HELEIBLM_00575 2.8e-08 phyR K Psort location Cytoplasmic, score
HELEIBLM_00576 3e-95 G Hypothetical glycosyl hydrolase 6
HELEIBLM_00579 8.9e-12
HELEIBLM_00580 3.2e-22 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
HELEIBLM_00581 1.2e-204 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HELEIBLM_00582 5.1e-145 atpB C it plays a direct role in the translocation of protons across the membrane
HELEIBLM_00583 1.5e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HELEIBLM_00584 2.9e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HELEIBLM_00585 2.3e-146 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HELEIBLM_00586 7.4e-305 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HELEIBLM_00587 4.1e-159 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HELEIBLM_00588 4.4e-280 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HELEIBLM_00589 1.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HELEIBLM_00590 5e-134 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HELEIBLM_00591 9.2e-157 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HELEIBLM_00592 3.9e-185
HELEIBLM_00593 1.9e-181
HELEIBLM_00594 3.7e-166 trxA2 O Tetratricopeptide repeat
HELEIBLM_00595 2.4e-118 cyaA 4.6.1.1 S CYTH
HELEIBLM_00597 4e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
HELEIBLM_00598 9.3e-183 plsC2 2.3.1.51 I Phosphate acyltransferases
HELEIBLM_00599 4.1e-181 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HELEIBLM_00600 3.8e-226 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HELEIBLM_00601 2.8e-205 P Bacterial extracellular solute-binding protein
HELEIBLM_00602 2.6e-156 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_00603 1.4e-129 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_00604 9.9e-228 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HELEIBLM_00605 1.1e-176 S CAAX protease self-immunity
HELEIBLM_00606 5.5e-128 M Mechanosensitive ion channel
HELEIBLM_00607 2.2e-268 aspA 4.3.1.1 E Fumarase C C-terminus
HELEIBLM_00608 7.3e-135 K Bacterial regulatory proteins, tetR family
HELEIBLM_00609 3.3e-237 MA20_36090 S Psort location Cytoplasmic, score 8.87
HELEIBLM_00610 6.5e-87 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HELEIBLM_00615 2.8e-23 yxiO G Major facilitator Superfamily
HELEIBLM_00616 1.6e-11 S Alpha/beta hydrolase family
HELEIBLM_00617 5.2e-21
HELEIBLM_00618 9.8e-189 K Helix-turn-helix XRE-family like proteins
HELEIBLM_00619 5e-19 yxiO G Major facilitator Superfamily
HELEIBLM_00620 9e-53 relB L RelB antitoxin
HELEIBLM_00621 2.7e-20 T Toxic component of a toxin-antitoxin (TA) module
HELEIBLM_00622 1.1e-130 K helix_turn_helix, mercury resistance
HELEIBLM_00623 2.1e-230 yxiO S Vacuole effluxer Atg22 like
HELEIBLM_00624 4.6e-196 yegV G pfkB family carbohydrate kinase
HELEIBLM_00625 5.5e-29 rpmB J Ribosomal L28 family
HELEIBLM_00626 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HELEIBLM_00627 3.1e-09 steT E amino acid
HELEIBLM_00628 2.3e-152 L Helix-turn-helix domain
HELEIBLM_00629 5.5e-96 L Resolvase, N terminal domain
HELEIBLM_00630 7.3e-38 O Bacterial Ig-like domain (group 3)
HELEIBLM_00631 4.1e-176 U Sodium:dicarboxylate symporter family
HELEIBLM_00632 2.5e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HELEIBLM_00633 1.3e-153 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HELEIBLM_00634 0.0 yegQ O Peptidase family U32 C-terminal domain
HELEIBLM_00635 3.1e-181 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HELEIBLM_00636 1.3e-157 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HELEIBLM_00637 3.5e-123 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HELEIBLM_00638 1.3e-59 D nuclear chromosome segregation
HELEIBLM_00639 2.6e-263 pepC 3.4.22.40 E Peptidase C1-like family
HELEIBLM_00640 6.7e-212 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HELEIBLM_00641 1.4e-234 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HELEIBLM_00642 3.1e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HELEIBLM_00643 1.7e-230 EGP Sugar (and other) transporter
HELEIBLM_00644 1.3e-204 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HELEIBLM_00645 1.8e-139 KT Transcriptional regulatory protein, C terminal
HELEIBLM_00646 8.8e-180 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HELEIBLM_00647 3.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HELEIBLM_00648 1.1e-168 pstA P Phosphate transport system permease
HELEIBLM_00649 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HELEIBLM_00650 4.3e-90 lemA S LemA family
HELEIBLM_00651 0.0 S Predicted membrane protein (DUF2207)
HELEIBLM_00652 4.5e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HELEIBLM_00653 2.6e-194 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HELEIBLM_00654 5.6e-122 K helix_turn _helix lactose operon repressor
HELEIBLM_00655 1.5e-140 G Bacterial extracellular solute-binding protein
HELEIBLM_00656 1.6e-118 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_00657 7.6e-112 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_00658 2.4e-226
HELEIBLM_00659 0.0 tetP J elongation factor G
HELEIBLM_00660 2.4e-28 Q Psort location Cytoplasmic, score
HELEIBLM_00661 5e-28 2.7.11.1 S Pfam:HipA_N
HELEIBLM_00662 7.5e-117 2.7.11.1 S Pfam:HipA_N
HELEIBLM_00663 1.5e-109 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HELEIBLM_00664 6.1e-35 CP_0960 S Belongs to the UPF0109 family
HELEIBLM_00665 8.3e-60 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HELEIBLM_00666 3.7e-140 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
HELEIBLM_00667 4e-267 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
HELEIBLM_00668 5e-212 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HELEIBLM_00669 2.8e-111 ribE 2.5.1.9 H Lumazine binding domain
HELEIBLM_00670 7.1e-236 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HELEIBLM_00671 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HELEIBLM_00672 4e-161 S Endonuclease/Exonuclease/phosphatase family
HELEIBLM_00673 1.2e-260 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HELEIBLM_00674 8.4e-30 L Phage integrase family
HELEIBLM_00675 2.7e-227 xerC_1 L Belongs to the 'phage' integrase family
HELEIBLM_00676 1.4e-80 L Phage integrase, N-terminal SAM-like domain
HELEIBLM_00677 2.8e-31 L Phage integrase, N-terminal SAM-like domain
HELEIBLM_00678 8e-288 uvrD2 3.6.4.12 L DNA helicase
HELEIBLM_00679 0.0 S Zincin-like metallopeptidase
HELEIBLM_00680 7.4e-158 lon T Belongs to the peptidase S16 family
HELEIBLM_00681 2e-44 S Protein of unknown function (DUF3052)
HELEIBLM_00683 8e-233 2.7.11.1 NU Tfp pilus assembly protein FimV
HELEIBLM_00684 4e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HELEIBLM_00685 8.2e-232 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HELEIBLM_00686 7.6e-284 I acetylesterase activity
HELEIBLM_00687 2.2e-112 recO L Involved in DNA repair and RecF pathway recombination
HELEIBLM_00688 5.8e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HELEIBLM_00689 4.8e-208 iunH1 3.2.2.1 F nucleoside hydrolase
HELEIBLM_00690 7e-203 P NMT1/THI5 like
HELEIBLM_00691 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00692 9.6e-302 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HELEIBLM_00693 3.1e-240 lacY P LacY proton/sugar symporter
HELEIBLM_00694 7.1e-192 K helix_turn _helix lactose operon repressor
HELEIBLM_00695 1.6e-242 O SERine Proteinase INhibitors
HELEIBLM_00696 9.2e-39
HELEIBLM_00697 1.2e-61 S Thiamine-binding protein
HELEIBLM_00698 1.1e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HELEIBLM_00699 4.9e-229 O AAA domain (Cdc48 subfamily)
HELEIBLM_00700 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HELEIBLM_00701 5.7e-164 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HELEIBLM_00702 8.2e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HELEIBLM_00703 1e-237 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HELEIBLM_00704 6.3e-192 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HELEIBLM_00705 7.5e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HELEIBLM_00706 3.9e-42 yggT S YGGT family
HELEIBLM_00707 7.8e-37 tccB2 V DivIVA protein
HELEIBLM_00708 1.2e-89 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HELEIBLM_00709 2.9e-179 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HELEIBLM_00710 7.1e-129 S Virulence factor BrkB
HELEIBLM_00711 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HELEIBLM_00712 3.1e-75 yneG S Domain of unknown function (DUF4186)
HELEIBLM_00713 0.0 4.2.1.53 S MCRA family
HELEIBLM_00714 1.5e-48 L Transposase and inactivated derivatives IS30 family
HELEIBLM_00716 1.7e-09 K Helix-turn-helix domain
HELEIBLM_00718 9.5e-275 L PFAM Integrase catalytic
HELEIBLM_00719 7.3e-133 L IstB-like ATP binding protein
HELEIBLM_00720 1.4e-47 G Bacterial extracellular solute-binding protein
HELEIBLM_00721 2.5e-113
HELEIBLM_00722 1.2e-49
HELEIBLM_00723 7.3e-112 S AIPR protein
HELEIBLM_00724 9e-106 M domain protein
HELEIBLM_00725 0.0 Q von Willebrand factor (vWF) type A domain
HELEIBLM_00726 1e-109
HELEIBLM_00728 8.9e-26 dexB 2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97 GH101,GH13,GH29,GH31 G hydrolase activity, hydrolyzing O-glycosyl compounds
HELEIBLM_00729 2.7e-97 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HELEIBLM_00731 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HELEIBLM_00732 5.5e-292 pccB I Carboxyl transferase domain
HELEIBLM_00733 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HELEIBLM_00734 1e-13 bioY S BioY family
HELEIBLM_00735 1.5e-142 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HELEIBLM_00736 0.0
HELEIBLM_00737 5.4e-137 QT PucR C-terminal helix-turn-helix domain
HELEIBLM_00738 2.5e-24 K helix_turn _helix lactose operon repressor
HELEIBLM_00739 7e-117 2.2.1.1 G Transketolase, pyrimidine binding domain
HELEIBLM_00740 3.2e-108 tktN 2.2.1.1 G Dehydrogenase E1 component
HELEIBLM_00741 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HELEIBLM_00742 6.2e-130 EGP Major facilitator Superfamily
HELEIBLM_00743 2.1e-08 ycnE S Antibiotic biosynthesis monooxygenase
HELEIBLM_00744 2.5e-115 iolT EGP Major facilitator Superfamily
HELEIBLM_00745 1.2e-128 iolE 4.2.1.44 G dehydratase
HELEIBLM_00746 4e-139 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HELEIBLM_00747 1.8e-104 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HELEIBLM_00748 2.5e-48 K helix_turn_helix, arabinose operon control protein
HELEIBLM_00749 1.5e-157 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HELEIBLM_00750 1.3e-83 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HELEIBLM_00751 5.2e-75 K Sugar-specific transcriptional regulator TrmB
HELEIBLM_00752 9.5e-69 K Bacterial transcriptional regulator
HELEIBLM_00753 7.1e-206 1.2.1.16, 1.2.1.20, 1.2.1.79 C Aldehyde dehydrogenase family
HELEIBLM_00754 2.4e-161 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
HELEIBLM_00755 1.9e-129 iolB 5.3.1.30 G PFAM Myo-inositol catabolism IolB domain protein
HELEIBLM_00756 1.4e-275 iolD 3.7.1.22 E Thiamine pyrophosphate enzyme, central domain
HELEIBLM_00757 7.7e-29 insK L Integrase core domain
HELEIBLM_00758 3.5e-52 FG bis(5'-adenosyl)-triphosphatase activity
HELEIBLM_00759 6.8e-177 uxaC 5.3.1.12 G Glucuronate isomerase
HELEIBLM_00760 2e-194 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HELEIBLM_00761 2e-233 rspA 4.2.1.8 M mandelate racemase muconate lactonizing
HELEIBLM_00762 3.6e-232 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HELEIBLM_00763 2.4e-67 K Periplasmic binding proteins and sugar binding domain of LacI family
HELEIBLM_00764 3.3e-61 K Periplasmic binding proteins and sugar binding domain of LacI family
HELEIBLM_00765 8.9e-48 G MFS/sugar transport protein
HELEIBLM_00766 1.3e-43 G MFS/sugar transport protein
HELEIBLM_00767 3e-19 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HELEIBLM_00768 9e-169 uxuT G MFS/sugar transport protein
HELEIBLM_00769 7.6e-91 L Transposase
HELEIBLM_00770 1.4e-31 L Transposase
HELEIBLM_00771 1.4e-50 L Phage integrase family
HELEIBLM_00773 1.9e-49
HELEIBLM_00774 1.1e-100 L PFAM Integrase catalytic
HELEIBLM_00775 1.2e-25 L PFAM Integrase catalytic
HELEIBLM_00776 8.2e-09 D nuclear chromosome segregation
HELEIBLM_00779 0.0 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HELEIBLM_00780 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HELEIBLM_00781 4.7e-120 K Bacterial regulatory proteins, tetR family
HELEIBLM_00782 2.2e-117 S Protein of unknown function, DUF624
HELEIBLM_00783 3.3e-250 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HELEIBLM_00784 0.0 G transport
HELEIBLM_00785 1.4e-167 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_00786 1.7e-179 P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00787 3.2e-77 L Transposase and inactivated derivatives IS30 family
HELEIBLM_00788 4.4e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HELEIBLM_00789 1.1e-50 ybjQ S Putative heavy-metal-binding
HELEIBLM_00790 3.8e-127 yplQ S Haemolysin-III related
HELEIBLM_00791 3.9e-64 hsp20 O Hsp20/alpha crystallin family
HELEIBLM_00792 1.7e-60 yoaZ S PfpI family
HELEIBLM_00794 4.4e-32 T Toxic component of a toxin-antitoxin (TA) module
HELEIBLM_00797 1e-25 L Transposase DDE domain
HELEIBLM_00799 3.7e-254 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HELEIBLM_00800 8.3e-245 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HELEIBLM_00801 0.0 cadA P E1-E2 ATPase
HELEIBLM_00802 6.5e-195 urtA E Receptor family ligand binding region
HELEIBLM_00803 2.5e-129 urtB U Branched-chain amino acid transport system / permease component
HELEIBLM_00804 2.6e-160 urtC U Branched-chain amino acid transport system / permease component
HELEIBLM_00805 3.4e-113 urtD S Branched-chain amino acid ATP-binding cassette transporter
HELEIBLM_00806 1.1e-98 urtE E ABC transporter
HELEIBLM_00807 1.7e-110 hoxN S rRNA processing
HELEIBLM_00808 3.2e-95 ureB 3.5.1.5 E Urease, gamma subunit
HELEIBLM_00809 1.6e-305 ureC 3.5.1.5 E Urease alpha-subunit, N-terminal domain
HELEIBLM_00810 2.5e-86 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HELEIBLM_00811 2.8e-82 ureF J Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HELEIBLM_00812 3.2e-99 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HELEIBLM_00813 1.4e-92 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HELEIBLM_00815 2.3e-265 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HELEIBLM_00816 8.4e-160 htpX O Belongs to the peptidase M48B family
HELEIBLM_00817 6.9e-116 3.2.1.4 GH5,GH9 S acid phosphatase activity
HELEIBLM_00819 1.8e-204 EGP Major Facilitator Superfamily
HELEIBLM_00820 2.9e-119 mug 3.2.2.28, 6.3.3.2 L Uracil DNA glycosylase superfamily
HELEIBLM_00821 1.4e-206 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HELEIBLM_00822 2.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HELEIBLM_00823 2.4e-281 clcA P Voltage gated chloride channel
HELEIBLM_00824 1.7e-121 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HELEIBLM_00825 8.7e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HELEIBLM_00826 7.1e-203 K helix_turn _helix lactose operon repressor
HELEIBLM_00827 8.2e-298 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HELEIBLM_00828 6e-270 scrT G Transporter major facilitator family protein
HELEIBLM_00829 1e-251 yhjE EGP Sugar (and other) transporter
HELEIBLM_00830 1.2e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HELEIBLM_00831 1.8e-51 bioN P Cobalt transport protein
HELEIBLM_00832 1.8e-72 cbiO P ATPases associated with a variety of cellular activities
HELEIBLM_00833 1.5e-58 bioY S BioY family
HELEIBLM_00834 1.5e-78 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HELEIBLM_00835 1.9e-112 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HELEIBLM_00836 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HELEIBLM_00837 1.5e-186 K Psort location Cytoplasmic, score
HELEIBLM_00838 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HELEIBLM_00839 5.8e-311 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HELEIBLM_00840 0.0 dnaK O Heat shock 70 kDa protein
HELEIBLM_00841 7e-55 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HELEIBLM_00842 5.7e-170 dnaJ1 O DnaJ molecular chaperone homology domain
HELEIBLM_00843 1.5e-98 hspR K transcriptional regulator, MerR family
HELEIBLM_00844 6.5e-214 F Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_00845 3.2e-206 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HELEIBLM_00846 9.4e-230 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HELEIBLM_00847 5.6e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HELEIBLM_00848 9.1e-124 S HAD hydrolase, family IA, variant 3
HELEIBLM_00849 6.1e-134 dedA S SNARE associated Golgi protein
HELEIBLM_00850 2.9e-93 cpaE D bacterial-type flagellum organization
HELEIBLM_00851 1.5e-192 cpaF U Type II IV secretion system protein
HELEIBLM_00852 2.1e-104 U Type ii secretion system
HELEIBLM_00853 3.1e-99 gspF NU Type II secretion system (T2SS), protein F
HELEIBLM_00854 4.6e-40 S Protein of unknown function (DUF4244)
HELEIBLM_00855 1.5e-53 S TIGRFAM helicase secretion neighborhood TadE-like protein
HELEIBLM_00856 4.2e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HELEIBLM_00857 3.7e-100 K Bacterial regulatory proteins, tetR family
HELEIBLM_00858 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HELEIBLM_00859 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HELEIBLM_00860 3.6e-205 3.4.22.70 M Sortase family
HELEIBLM_00861 1.3e-38 S Psort location Cytoplasmic, score
HELEIBLM_00862 2.3e-131 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HELEIBLM_00863 8e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
HELEIBLM_00864 3e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HELEIBLM_00865 1.3e-113
HELEIBLM_00866 1.1e-308 S Calcineurin-like phosphoesterase
HELEIBLM_00867 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HELEIBLM_00868 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HELEIBLM_00869 1.2e-166 3.6.1.27 I PAP2 superfamily
HELEIBLM_00870 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HELEIBLM_00871 6.8e-122 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HELEIBLM_00872 4e-204 holB 2.7.7.7 L DNA polymerase III
HELEIBLM_00873 8.6e-100 K helix_turn _helix lactose operon repressor
HELEIBLM_00874 3.3e-37 ptsH G PTS HPr component phosphorylation site
HELEIBLM_00876 9.5e-292 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HELEIBLM_00877 5.6e-106 S Phosphatidylethanolamine-binding protein
HELEIBLM_00878 0.0 pepD E Peptidase family C69
HELEIBLM_00879 2.4e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HELEIBLM_00880 5.1e-62 S Macrophage migration inhibitory factor (MIF)
HELEIBLM_00881 2.4e-95 S GtrA-like protein
HELEIBLM_00882 5.5e-259 EGP Major facilitator Superfamily
HELEIBLM_00883 1.7e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HELEIBLM_00884 4.9e-157
HELEIBLM_00885 8.4e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HELEIBLM_00886 1.1e-139 S Protein of unknown function (DUF805)
HELEIBLM_00887 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HELEIBLM_00888 4.5e-169 V Abi-like protein
HELEIBLM_00889 1.4e-29 3.1.21.3 V type I restriction modification DNA specificity domain
HELEIBLM_00890 4.1e-110 3.1.21.3 V Type I restriction modification DNA specificity domain
HELEIBLM_00892 3.7e-293 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HELEIBLM_00893 2.7e-293 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HELEIBLM_00896 1.3e-66
HELEIBLM_00897 9.4e-134 yoaK S Protein of unknown function (DUF1275)
HELEIBLM_00898 5e-96 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_00900 5.6e-177 2.7.7.7 L Transposase, Mutator family
HELEIBLM_00902 4.6e-311
HELEIBLM_00903 0.0 efeU_1 P Iron permease FTR1 family
HELEIBLM_00904 5.5e-108 tpd P Fe2+ transport protein
HELEIBLM_00905 1.7e-232 S Predicted membrane protein (DUF2318)
HELEIBLM_00906 9.1e-213 macB_2 V ABC transporter permease
HELEIBLM_00907 1.6e-214 Z012_06715 V FtsX-like permease family
HELEIBLM_00908 5.9e-146 macB V ABC transporter, ATP-binding protein
HELEIBLM_00909 2.8e-65 S FMN_bind
HELEIBLM_00910 8.3e-105 K Psort location Cytoplasmic, score 8.87
HELEIBLM_00911 2e-305 pip S YhgE Pip domain protein
HELEIBLM_00912 0.0 pip S YhgE Pip domain protein
HELEIBLM_00913 8.6e-232 S Putative ABC-transporter type IV
HELEIBLM_00914 2.3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HELEIBLM_00915 8.7e-140 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HELEIBLM_00916 2e-183 opcA G Glucose-6-phosphate dehydrogenase subunit
HELEIBLM_00917 1.8e-300 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HELEIBLM_00919 1.5e-39
HELEIBLM_00920 7.1e-09
HELEIBLM_00921 1.1e-257 pepD E Peptidase family C69
HELEIBLM_00922 3.4e-186 XK27_01805 M Glycosyltransferase like family 2
HELEIBLM_00923 1.6e-123 icaR K Bacterial regulatory proteins, tetR family
HELEIBLM_00924 1.1e-44 S Protein of unknown function (DUF2089)
HELEIBLM_00925 4.6e-17
HELEIBLM_00926 2.7e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HELEIBLM_00927 4.5e-228 amt U Ammonium Transporter Family
HELEIBLM_00928 1e-54 glnB K Nitrogen regulatory protein P-II
HELEIBLM_00929 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HELEIBLM_00930 1.3e-249 dinF V MatE
HELEIBLM_00931 4.4e-275 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HELEIBLM_00932 3.1e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HELEIBLM_00933 1.2e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HELEIBLM_00934 1e-31 S granule-associated protein
HELEIBLM_00935 0.0 ubiB S ABC1 family
HELEIBLM_00936 3.5e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HELEIBLM_00937 2.6e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HELEIBLM_00938 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HELEIBLM_00939 6.2e-66 ssb1 L Single-stranded DNA-binding protein
HELEIBLM_00940 2.6e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HELEIBLM_00941 1.9e-69 rplI J Binds to the 23S rRNA
HELEIBLM_00943 1.7e-37 L Transposase
HELEIBLM_00944 3.8e-117
HELEIBLM_00945 4e-130 V ABC transporter
HELEIBLM_00946 6.2e-107 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HELEIBLM_00947 3.2e-201 2.7.13.3 T Histidine kinase
HELEIBLM_00948 9.7e-201 EGP Major Facilitator Superfamily
HELEIBLM_00949 1.8e-16 ybiR P Citrate transporter
HELEIBLM_00950 9.1e-273 EK Alanine-glyoxylate amino-transferase
HELEIBLM_00951 1.2e-114 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HELEIBLM_00952 2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HELEIBLM_00953 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HELEIBLM_00954 7.9e-249 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HELEIBLM_00955 2.6e-250 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HELEIBLM_00956 2.2e-271 yhdG E aromatic amino acid transport protein AroP K03293
HELEIBLM_00957 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HELEIBLM_00958 4.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HELEIBLM_00959 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HELEIBLM_00960 4.2e-295 enhA_2 S L,D-transpeptidase catalytic domain
HELEIBLM_00961 3.4e-222 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HELEIBLM_00962 4.1e-91 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HELEIBLM_00964 7.1e-171 EGP Major Facilitator Superfamily
HELEIBLM_00965 1.2e-148 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HELEIBLM_00966 9.3e-09 sapF E ATPases associated with a variety of cellular activities
HELEIBLM_00967 9e-121 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HELEIBLM_00968 8.8e-125 EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_00969 1.7e-160 P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00970 2.4e-282 E ABC transporter, substrate-binding protein, family 5
HELEIBLM_00971 8.5e-243 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HELEIBLM_00972 9.3e-141 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HELEIBLM_00973 3.2e-264 G Bacterial extracellular solute-binding protein
HELEIBLM_00974 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HELEIBLM_00975 1.5e-111 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HELEIBLM_00976 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HELEIBLM_00977 1.3e-148 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HELEIBLM_00978 4.8e-150 yecS E Binding-protein-dependent transport system inner membrane component
HELEIBLM_00979 2.8e-163 pknD ET ABC transporter, substrate-binding protein, family 3
HELEIBLM_00980 8.6e-144 pknD ET ABC transporter, substrate-binding protein, family 3
HELEIBLM_00981 1.8e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HELEIBLM_00982 2.6e-157 usp 3.5.1.28 CBM50 D CHAP domain protein
HELEIBLM_00983 5.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HELEIBLM_00984 4.7e-176 ftsE D Cell division ATP-binding protein FtsE
HELEIBLM_00985 2.4e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HELEIBLM_00986 1.1e-253 S Domain of unknown function (DUF4143)
HELEIBLM_00987 1e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HELEIBLM_00988 5.2e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HELEIBLM_00989 4.9e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HELEIBLM_00990 6.8e-98 ugpA P Binding-protein-dependent transport system inner membrane component
HELEIBLM_00991 3.6e-153 ugpB G Bacterial extracellular solute-binding protein
HELEIBLM_00992 1.2e-99 ugpQ 3.1.4.46 C Domain of unknown function
HELEIBLM_00993 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HELEIBLM_00994 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HELEIBLM_00995 1e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HELEIBLM_00996 1e-131 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HELEIBLM_00997 2.3e-224 G Major Facilitator Superfamily
HELEIBLM_00998 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HELEIBLM_00999 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HELEIBLM_01000 2.2e-260 KLT Protein tyrosine kinase
HELEIBLM_01001 0.0 S Fibronectin type 3 domain
HELEIBLM_01002 2e-175 S ATPase family associated with various cellular activities (AAA)
HELEIBLM_01003 1.8e-223 S Protein of unknown function DUF58
HELEIBLM_01004 0.0 E Transglutaminase-like superfamily
HELEIBLM_01005 9.3e-26 3.1.3.16 T Sigma factor PP2C-like phosphatases
HELEIBLM_01006 4e-68 B Belongs to the OprB family
HELEIBLM_01007 1.9e-83 T Forkhead associated domain
HELEIBLM_01008 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELEIBLM_01009 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELEIBLM_01010 7.5e-108
HELEIBLM_01011 2.5e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HELEIBLM_01012 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HELEIBLM_01013 3e-251 S UPF0210 protein
HELEIBLM_01014 1.9e-43 gcvR T Belongs to the UPF0237 family
HELEIBLM_01016 1.7e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HELEIBLM_01017 1.4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HELEIBLM_01018 6.9e-122 glpR K DeoR C terminal sensor domain
HELEIBLM_01019 1.3e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HELEIBLM_01020 1e-222 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HELEIBLM_01021 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HELEIBLM_01022 2.8e-132 glxR K helix_turn_helix, cAMP Regulatory protein
HELEIBLM_01023 1.5e-197 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HELEIBLM_01024 1.6e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HELEIBLM_01025 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HELEIBLM_01026 3.3e-250 S Uncharacterized conserved protein (DUF2183)
HELEIBLM_01027 3.6e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HELEIBLM_01028 3.4e-228 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HELEIBLM_01029 7.7e-160 mhpC I Alpha/beta hydrolase family
HELEIBLM_01030 4e-124 F Domain of unknown function (DUF4916)
HELEIBLM_01031 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HELEIBLM_01032 1.7e-171 S G5
HELEIBLM_01033 1.1e-18 hipB K Helix-turn-helix XRE-family like proteins
HELEIBLM_01034 4.4e-133 2.7.11.1 S HipA-like C-terminal domain
HELEIBLM_01035 4.4e-112
HELEIBLM_01036 1.6e-231 wcoI DM Psort location CytoplasmicMembrane, score
HELEIBLM_01037 3e-262 S Psort location CytoplasmicMembrane, score 9.99
HELEIBLM_01038 1.5e-20 S enterobacterial common antigen metabolic process
HELEIBLM_01039 1.6e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
HELEIBLM_01040 3.9e-79 S RloB-like protein
HELEIBLM_01042 3e-19 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HELEIBLM_01044 1.6e-24
HELEIBLM_01045 4.9e-59 L Helix-turn-helix domain
HELEIBLM_01046 2.9e-125 S AAA-like domain
HELEIBLM_01047 3.5e-211 S AAA-like domain
HELEIBLM_01048 8.3e-50 S SIR2-like domain
HELEIBLM_01049 6.9e-146 tnp7109-21 L Integrase core domain
HELEIBLM_01050 3.7e-27 L Transposase
HELEIBLM_01052 4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HELEIBLM_01053 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
HELEIBLM_01054 1.1e-41 csoR S Metal-sensitive transcriptional repressor
HELEIBLM_01055 5e-188 rmuC S RmuC family
HELEIBLM_01056 4.7e-98 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HELEIBLM_01057 1.4e-158 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HELEIBLM_01058 4.6e-185 K Psort location Cytoplasmic, score
HELEIBLM_01059 2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HELEIBLM_01060 5.1e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HELEIBLM_01061 7.9e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HELEIBLM_01062 5.2e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
HELEIBLM_01063 3.3e-52 S Protein of unknown function (DUF2469)
HELEIBLM_01064 4.6e-282 S Histidine phosphatase superfamily (branch 2)
HELEIBLM_01065 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HELEIBLM_01066 7.7e-243 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HELEIBLM_01067 1.8e-201 K helix_turn _helix lactose operon repressor
HELEIBLM_01068 3e-291 EGP Major Facilitator Superfamily
HELEIBLM_01070 1.4e-173 glkA 2.7.1.2 G ROK family
HELEIBLM_01071 6.4e-62 EGP Major facilitator superfamily
HELEIBLM_01072 1.1e-163 dkgB S Oxidoreductase, aldo keto reductase family protein
HELEIBLM_01073 1.1e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HELEIBLM_01074 1.3e-145
HELEIBLM_01075 1.2e-22 EGP Major facilitator Superfamily
HELEIBLM_01076 1.7e-69 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HELEIBLM_01077 7.2e-228 xylR GK ROK family
HELEIBLM_01079 1.3e-36 rpmE J Binds the 23S rRNA
HELEIBLM_01080 5.3e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HELEIBLM_01081 1.1e-153 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HELEIBLM_01082 9.5e-201 livK E Receptor family ligand binding region
HELEIBLM_01083 1.2e-105 U Belongs to the binding-protein-dependent transport system permease family
HELEIBLM_01084 1.1e-171 livM U Belongs to the binding-protein-dependent transport system permease family
HELEIBLM_01085 3.1e-153 E Branched-chain amino acid ATP-binding cassette transporter
HELEIBLM_01086 1.5e-121 livF E ATPases associated with a variety of cellular activities
HELEIBLM_01087 1.2e-35 yncA 2.3.1.18, 2.3.1.79 S O-acyltransferase activity
HELEIBLM_01088 2.3e-119 ywlC 2.7.7.87 J Belongs to the SUA5 family
HELEIBLM_01089 1.3e-203 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HELEIBLM_01090 7.6e-291 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HELEIBLM_01091 1e-116 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HELEIBLM_01092 2.6e-269 recD2 3.6.4.12 L PIF1-like helicase
HELEIBLM_01093 7.2e-63 S AMMECR1
HELEIBLM_01094 4e-183 L PFAM Integrase catalytic
HELEIBLM_01095 6.6e-27 gutA G Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_01097 1.8e-37 gutA G Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_01098 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
HELEIBLM_01099 2.1e-61 L Transposase
HELEIBLM_01100 2.4e-11 L PFAM Relaxase mobilization nuclease family protein
HELEIBLM_01101 5.1e-18 bglK 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HELEIBLM_01102 4.8e-219 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HELEIBLM_01103 7.7e-70 S Nucleotidyltransferase substrate binding protein like
HELEIBLM_01104 1.2e-45 S Nucleotidyltransferase domain
HELEIBLM_01106 2.1e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HELEIBLM_01107 5.1e-54 L Helix-turn-helix domain
HELEIBLM_01108 4.3e-15 G Glycosyl hydrolase family 85
HELEIBLM_01109 1e-176 endOF2 3.2.1.14, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
HELEIBLM_01110 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
HELEIBLM_01111 1.6e-257 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HELEIBLM_01112 3e-156 lacG G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01113 2.6e-164 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01114 1.1e-245 srrA1 G Bacterial extracellular solute-binding protein
HELEIBLM_01115 6.3e-13 L Helix-turn-helix domain
HELEIBLM_01116 3.4e-46 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HELEIBLM_01118 1.1e-09 nagH 2.7.13.3, 3.2.1.52 GH20 M Domain of unknown function (DUF5011)
HELEIBLM_01119 7.4e-186 S Domain of unknown function (DUF4143)
HELEIBLM_01120 1.7e-12 L Psort location Cytoplasmic, score 8.87
HELEIBLM_01121 7.2e-27 L Psort location Cytoplasmic, score 8.87
HELEIBLM_01122 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
HELEIBLM_01123 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
HELEIBLM_01124 1.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HELEIBLM_01125 9.8e-46
HELEIBLM_01126 6.4e-24 S Phage derived protein Gp49-like (DUF891)
HELEIBLM_01127 3.9e-44 K Addiction module
HELEIBLM_01128 9.5e-54 S enterobacterial common antigen metabolic process
HELEIBLM_01129 9.7e-24 pslL G Acyltransferase family
HELEIBLM_01130 3.6e-36 lacS G Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_01131 1.3e-132 L Transposase, Mutator family
HELEIBLM_01134 2.5e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HELEIBLM_01135 4.4e-197 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HELEIBLM_01136 4.2e-135 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HELEIBLM_01137 2e-80 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HELEIBLM_01138 4.3e-26 rpmI J Ribosomal protein L35
HELEIBLM_01139 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HELEIBLM_01140 1.2e-169 xerD D recombinase XerD
HELEIBLM_01141 8.1e-150 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HELEIBLM_01142 1.6e-155 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HELEIBLM_01143 5.3e-114 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HELEIBLM_01144 1.8e-153 nrtR 3.6.1.55 F NUDIX hydrolase
HELEIBLM_01145 8.3e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HELEIBLM_01146 2.4e-303 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HELEIBLM_01147 7.2e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HELEIBLM_01148 1.1e-215 iscS1 2.8.1.7 E Aminotransferase class-V
HELEIBLM_01149 0.0 typA T Elongation factor G C-terminus
HELEIBLM_01150 1.3e-12 EGP Major facilitator Superfamily
HELEIBLM_01151 1.4e-37 L PFAM Integrase catalytic
HELEIBLM_01152 2.4e-72
HELEIBLM_01153 4.3e-191 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HELEIBLM_01154 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HELEIBLM_01155 2e-42
HELEIBLM_01156 9.2e-179 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HELEIBLM_01157 2.3e-311 E ABC transporter, substrate-binding protein, family 5
HELEIBLM_01158 1.1e-151 dppB EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_01159 8.7e-171 dppC EP N-terminal TM domain of oligopeptide transport permease C
HELEIBLM_01160 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HELEIBLM_01161 6.3e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HELEIBLM_01162 1.1e-147 S Protein of unknown function (DUF3710)
HELEIBLM_01163 9.6e-130 S Protein of unknown function (DUF3159)
HELEIBLM_01164 2e-241 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HELEIBLM_01165 3.7e-104
HELEIBLM_01166 0.0 ctpE P E1-E2 ATPase
HELEIBLM_01167 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HELEIBLM_01168 3.6e-58 relB L RelB antitoxin
HELEIBLM_01169 2.1e-85 S PIN domain
HELEIBLM_01170 0.0 S Protein of unknown function DUF262
HELEIBLM_01171 5.5e-118 E Psort location Cytoplasmic, score 8.87
HELEIBLM_01172 1.5e-126 ybhL S Belongs to the BI1 family
HELEIBLM_01173 4.1e-176 ydeD EG EamA-like transporter family
HELEIBLM_01174 1.7e-135 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HELEIBLM_01175 3.7e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HELEIBLM_01176 5.7e-183 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HELEIBLM_01177 2.3e-136 fic D Fic/DOC family
HELEIBLM_01178 0.0 ftsK D FtsK SpoIIIE family protein
HELEIBLM_01179 1.6e-49 K MarR family
HELEIBLM_01180 8.7e-91 V ABC transporter, ATP-binding protein
HELEIBLM_01181 4.4e-165 V ABC transporter, ATP-binding protein
HELEIBLM_01182 0.0 V ABC transporter transmembrane region
HELEIBLM_01183 1.3e-111 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HELEIBLM_01184 1.1e-90 cinA 3.5.1.42 S Belongs to the CinA family
HELEIBLM_01185 4.7e-80 K Helix-turn-helix XRE-family like proteins
HELEIBLM_01186 5.3e-39 S Protein of unknown function (DUF3046)
HELEIBLM_01187 2.6e-198 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HELEIBLM_01188 5.2e-99 recX S Modulates RecA activity
HELEIBLM_01189 3.7e-109 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HELEIBLM_01190 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HELEIBLM_01191 3.1e-65 E GDSL-like Lipase/Acylhydrolase family
HELEIBLM_01192 7.4e-173 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HELEIBLM_01193 2.6e-75
HELEIBLM_01194 1.7e-128 plsC2 2.3.1.51 I Phosphate acyltransferases
HELEIBLM_01195 0.0 pknL 2.7.11.1 KLT PASTA
HELEIBLM_01196 2.4e-190 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HELEIBLM_01197 7.6e-123
HELEIBLM_01198 5.8e-189 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HELEIBLM_01199 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HELEIBLM_01200 7e-199 G Major Facilitator Superfamily
HELEIBLM_01201 1e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HELEIBLM_01202 0.0 lhr L DEAD DEAH box helicase
HELEIBLM_01203 2.4e-123 KT RESPONSE REGULATOR receiver
HELEIBLM_01204 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HELEIBLM_01205 2.4e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
HELEIBLM_01206 6.1e-178 S Protein of unknown function (DUF3071)
HELEIBLM_01207 3.9e-47 S Domain of unknown function (DUF4193)
HELEIBLM_01208 6.1e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HELEIBLM_01209 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HELEIBLM_01210 2.3e-74
HELEIBLM_01212 1.5e-242 S HipA-like C-terminal domain
HELEIBLM_01213 6e-157 S Fic/DOC family
HELEIBLM_01214 1e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
HELEIBLM_01215 5e-116 K WHG domain
HELEIBLM_01216 2.9e-22 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
HELEIBLM_01217 5.5e-265 EGP Major Facilitator Superfamily
HELEIBLM_01218 2.3e-24 S AAA ATPase domain
HELEIBLM_01221 2.3e-241 mloB K Putative DNA-binding domain
HELEIBLM_01222 8.4e-29 L Transposase and inactivated derivatives IS30 family
HELEIBLM_01223 4.3e-17 S ATP diphosphatase activity
HELEIBLM_01224 5.6e-196
HELEIBLM_01225 6.9e-110 3.4.13.21 E Peptidase family S51
HELEIBLM_01226 2.2e-108 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HELEIBLM_01227 1.2e-65 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HELEIBLM_01228 5.1e-165 M pfam nlp p60
HELEIBLM_01229 4.8e-159 I Serine aminopeptidase, S33
HELEIBLM_01230 2.4e-40 S Protein of unknown function (DUF2975)
HELEIBLM_01231 2.8e-31 yozG K Cro/C1-type HTH DNA-binding domain
HELEIBLM_01232 5.4e-240 pbuX F Permease family
HELEIBLM_01233 8.2e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HELEIBLM_01234 0.0 pcrA 3.6.4.12 L DNA helicase
HELEIBLM_01235 4.5e-62 S Domain of unknown function (DUF4418)
HELEIBLM_01236 4.4e-217 V FtsX-like permease family
HELEIBLM_01237 2.6e-135 lolD V ABC transporter
HELEIBLM_01238 4.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HELEIBLM_01239 2.3e-150 S Peptidase C26
HELEIBLM_01240 3e-65 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HELEIBLM_01241 1.2e-48 relB L RelB antitoxin
HELEIBLM_01242 1.2e-128 pgm3 G Phosphoglycerate mutase family
HELEIBLM_01243 2e-62 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HELEIBLM_01244 1.4e-34
HELEIBLM_01245 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HELEIBLM_01246 5.1e-78 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HELEIBLM_01247 2.5e-201 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HELEIBLM_01248 2.6e-77 3.4.23.43 S Type IV leader peptidase family
HELEIBLM_01249 1.1e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HELEIBLM_01250 7.6e-310 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HELEIBLM_01251 2e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HELEIBLM_01252 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HELEIBLM_01253 1.1e-291 sufB O FeS assembly protein SufB
HELEIBLM_01254 2.5e-236 sufD O FeS assembly protein SufD
HELEIBLM_01255 1.6e-143 sufC O FeS assembly ATPase SufC
HELEIBLM_01256 9.4e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HELEIBLM_01257 3.1e-101 iscU C SUF system FeS assembly protein, NifU family
HELEIBLM_01258 1.6e-111 yitW S Iron-sulfur cluster assembly protein
HELEIBLM_01259 2.9e-240 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HELEIBLM_01260 7.6e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
HELEIBLM_01262 1.6e-143 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HELEIBLM_01263 7.5e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HELEIBLM_01264 1.2e-211 phoH T PhoH-like protein
HELEIBLM_01265 1.4e-101 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HELEIBLM_01266 4.6e-250 corC S CBS domain
HELEIBLM_01267 2.3e-182 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HELEIBLM_01268 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HELEIBLM_01269 1.4e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HELEIBLM_01270 2.7e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HELEIBLM_01271 8.4e-236 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HELEIBLM_01272 2.2e-193 S alpha beta
HELEIBLM_01273 1.2e-82 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HELEIBLM_01274 3.1e-225 ilvE 2.6.1.42 E Amino-transferase class IV
HELEIBLM_01275 5.7e-74 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
HELEIBLM_01276 1.9e-125 S UPF0126 domain
HELEIBLM_01277 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HELEIBLM_01278 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HELEIBLM_01279 5.4e-180 hemN H Involved in the biosynthesis of porphyrin-containing compound
HELEIBLM_01280 3.3e-134 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HELEIBLM_01283 1e-177 K helix_turn _helix lactose operon repressor
HELEIBLM_01284 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HELEIBLM_01285 1.7e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HELEIBLM_01286 3.8e-309 E ABC transporter, substrate-binding protein, family 5
HELEIBLM_01287 0.0 S Glycosyl hydrolases related to GH101 family, GH129
HELEIBLM_01288 1e-81
HELEIBLM_01289 1.4e-239 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HELEIBLM_01290 7.1e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HELEIBLM_01291 1.2e-157 S Sucrose-6F-phosphate phosphohydrolase
HELEIBLM_01292 9.2e-113 ybeM S Carbon-nitrogen hydrolase
HELEIBLM_01293 4.9e-73 bcp 1.11.1.15 O Redoxin
HELEIBLM_01294 8e-130
HELEIBLM_01296 5.9e-120 2.5.1.19 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HELEIBLM_01297 5.2e-228 K SIR2-like domain
HELEIBLM_01299 4.1e-108 S Putative inner membrane protein (DUF1819)
HELEIBLM_01300 3e-125 S Domain of unknown function (DUF1788)
HELEIBLM_01301 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HELEIBLM_01302 0.0 LV DNA restriction-modification system
HELEIBLM_01303 0.0 K SIR2-like domain
HELEIBLM_01304 5.9e-256 lexA 3.6.4.12 K Putative DNA-binding domain
HELEIBLM_01305 0.0 thiN 2.7.6.2 H PglZ domain
HELEIBLM_01306 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
HELEIBLM_01307 4.8e-178 CP_1020 S zinc ion binding
HELEIBLM_01308 2.6e-169 I alpha/beta hydrolase fold
HELEIBLM_01309 7.6e-12 ydhF S Aldo/keto reductase family
HELEIBLM_01310 2.5e-23 ydhF S Aldo/keto reductase family
HELEIBLM_01311 2e-44 S phosphoesterase or phosphohydrolase
HELEIBLM_01312 7.1e-130 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HELEIBLM_01314 7.9e-93 S Phospholipase/Carboxylesterase
HELEIBLM_01315 2.3e-193 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HELEIBLM_01316 3e-96 sixA 3.6.1.55 T Phosphoglycerate mutase family
HELEIBLM_01317 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HELEIBLM_01318 3.3e-155 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HELEIBLM_01319 1.1e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HELEIBLM_01320 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HELEIBLM_01321 2.7e-177 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HELEIBLM_01322 1e-72 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HELEIBLM_01323 5.1e-284 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HELEIBLM_01324 2.1e-174 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HELEIBLM_01325 4.5e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HELEIBLM_01326 1.2e-180 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HELEIBLM_01327 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HELEIBLM_01328 9e-29
HELEIBLM_01329 6.4e-207 MA20_36090 S Psort location Cytoplasmic, score 8.87
HELEIBLM_01330 8e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HELEIBLM_01331 3.3e-120 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HELEIBLM_01332 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HELEIBLM_01333 1.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HELEIBLM_01334 9.7e-119 XK27_08510 KL DEAD-like helicases superfamily
HELEIBLM_01335 5e-61 yeaO K Protein of unknown function, DUF488
HELEIBLM_01336 3e-21 S Virulence protein RhuM family
HELEIBLM_01337 2e-07 V ATPases associated with a variety of cellular activities
HELEIBLM_01338 1.2e-15 yijF S Domain of unknown function (DUF1287)
HELEIBLM_01339 6.5e-156 3.6.4.12
HELEIBLM_01340 3.8e-75
HELEIBLM_01341 1.1e-64 yeaO K Protein of unknown function, DUF488
HELEIBLM_01343 1.2e-288 mmuP E amino acid
HELEIBLM_01344 6e-74 2.6.1.76 EGP Major Facilitator Superfamily
HELEIBLM_01346 3.7e-93 yidC U Membrane protein insertase, YidC Oxa1 family
HELEIBLM_01347 8.4e-116 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
HELEIBLM_01348 1.3e-31 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HELEIBLM_01349 1.2e-53 hipA 2.7.11.1 S kinase activity
HELEIBLM_01350 6.3e-45 K sequence-specific DNA binding
HELEIBLM_01351 1.8e-26 S Polyketide cyclase / dehydrase and lipid transport
HELEIBLM_01352 1.9e-107
HELEIBLM_01355 5.2e-121
HELEIBLM_01356 3.3e-50
HELEIBLM_01358 2.4e-36
HELEIBLM_01360 9e-29 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HELEIBLM_01361 1.7e-78 GT2,GT4 M Glycosyl transferase family 2
HELEIBLM_01362 2.3e-112 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
HELEIBLM_01363 4.3e-92 M Polysaccharide pyruvyl transferase
HELEIBLM_01364 2.4e-106 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HELEIBLM_01365 3e-73 rgpC GM Transport permease protein
HELEIBLM_01366 1.1e-32 L Helix-turn-helix domain
HELEIBLM_01367 8.2e-152 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HELEIBLM_01368 2.5e-264 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HELEIBLM_01369 6.6e-24
HELEIBLM_01370 6.5e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HELEIBLM_01371 1.6e-72 L Transposase and inactivated derivatives IS30 family
HELEIBLM_01372 2.3e-20 L Transposase and inactivated derivatives IS30 family
HELEIBLM_01373 4.5e-09 L Transposase and inactivated derivatives IS30 family
HELEIBLM_01374 1.8e-153 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HELEIBLM_01375 1.3e-171 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_01376 3.3e-157 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
HELEIBLM_01377 3.3e-58 rfbJ M Glycosyl transferase family 2
HELEIBLM_01378 2e-42 rfbJ M Glycosyl transferase family 2
HELEIBLM_01379 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HELEIBLM_01380 2.2e-160
HELEIBLM_01381 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HELEIBLM_01382 4.7e-279 pelF GT4 M Domain of unknown function (DUF3492)
HELEIBLM_01383 2.6e-267 pelG S Putative exopolysaccharide Exporter (EPS-E)
HELEIBLM_01384 1.5e-309 cotH M CotH kinase protein
HELEIBLM_01385 3.2e-155 P VTC domain
HELEIBLM_01386 6.1e-109 S Domain of unknown function (DUF4956)
HELEIBLM_01387 0.0 yliE T Putative diguanylate phosphodiesterase
HELEIBLM_01388 6.7e-92 V ABC transporter, ATP-binding protein
HELEIBLM_01389 5.4e-248 V ABC transporter transmembrane region
HELEIBLM_01390 3e-134 rbsR K helix_turn _helix lactose operon repressor
HELEIBLM_01391 3.3e-164 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HELEIBLM_01392 6.7e-185 EGP Major facilitator Superfamily
HELEIBLM_01393 5.2e-21 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HELEIBLM_01394 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HELEIBLM_01395 2.9e-174 lacR K Transcriptional regulator, LacI family
HELEIBLM_01396 1.7e-107 K FCD
HELEIBLM_01397 1.8e-143 L Domain of unknown function (DUF4862)
HELEIBLM_01398 1e-120 2.7.1.2 GK ROK family
HELEIBLM_01399 1.6e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HELEIBLM_01400 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
HELEIBLM_01401 1.2e-270 E Bacterial extracellular solute-binding proteins, family 5 Middle
HELEIBLM_01402 7.2e-167 oppB6 EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_01403 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
HELEIBLM_01404 8.5e-143 oppF E ATPases associated with a variety of cellular activities
HELEIBLM_01405 8.7e-160 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
HELEIBLM_01406 2.3e-242 malY 4.4.1.8 E Aminotransferase, class I II
HELEIBLM_01407 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HELEIBLM_01408 3.4e-251 L DEAD-like helicases superfamily
HELEIBLM_01409 6.6e-149 cas7c L CRISPR-associated protein Cas7
HELEIBLM_01410 4.1e-111 cas4 3.1.12.1 L Domain of unknown function DUF83
HELEIBLM_01411 5.8e-178 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HELEIBLM_01412 1.3e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HELEIBLM_01413 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HELEIBLM_01414 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HELEIBLM_01415 4.5e-110 nusG K Participates in transcription elongation, termination and antitermination
HELEIBLM_01416 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HELEIBLM_01418 9.9e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HELEIBLM_01419 8.3e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HELEIBLM_01420 2.9e-304 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HELEIBLM_01421 8.8e-40 rpmA J Ribosomal L27 protein
HELEIBLM_01422 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HELEIBLM_01423 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HELEIBLM_01424 8e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
HELEIBLM_01425 6.1e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HELEIBLM_01426 9.4e-77 fucU 5.1.3.29 G RbsD / FucU transport protein family
HELEIBLM_01427 5.1e-147 S Amidohydrolase
HELEIBLM_01428 1.4e-202 fucP G Major Facilitator Superfamily
HELEIBLM_01429 4.3e-141 IQ KR domain
HELEIBLM_01430 1.4e-245 4.2.1.68 M Enolase C-terminal domain-like
HELEIBLM_01431 1.5e-181 K Bacterial regulatory proteins, lacI family
HELEIBLM_01432 1.2e-253 V Efflux ABC transporter, permease protein
HELEIBLM_01433 1.5e-132 V ATPases associated with a variety of cellular activities
HELEIBLM_01435 3e-08 K Acetyltransferase (GNAT) family
HELEIBLM_01436 2e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HELEIBLM_01437 2.9e-182 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HELEIBLM_01438 1.4e-232 hom 1.1.1.3 E Homoserine dehydrogenase
HELEIBLM_01439 1.6e-291 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HELEIBLM_01440 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HELEIBLM_01441 4.3e-172 K LysR substrate binding domain protein
HELEIBLM_01442 2.3e-245 patB 4.4.1.8 E Aminotransferase, class I II
HELEIBLM_01443 4.1e-253 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HELEIBLM_01444 8.4e-254 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HELEIBLM_01445 1.9e-206 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HELEIBLM_01446 3.5e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HELEIBLM_01447 5.7e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HELEIBLM_01448 1.6e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HELEIBLM_01449 1.4e-259 S Calcineurin-like phosphoesterase
HELEIBLM_01450 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HELEIBLM_01451 1.4e-212 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HELEIBLM_01452 6.7e-129
HELEIBLM_01453 2e-47 lacS G Psort location CytoplasmicMembrane, score 10.00
HELEIBLM_01454 1e-282 G Glycosyl hydrolase family 85
HELEIBLM_01455 2e-54 G Glycosyl hydrolase family 85
HELEIBLM_01456 9.2e-74 G Glycosyl hydrolase family 85
HELEIBLM_01457 8.6e-204 K helix_turn _helix lactose operon repressor
HELEIBLM_01458 3e-234 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HELEIBLM_01459 3.8e-259 S Metal-independent alpha-mannosidase (GH125)
HELEIBLM_01460 1.2e-168 2.7.1.4 G pfkB family carbohydrate kinase
HELEIBLM_01461 3e-218 GK ROK family
HELEIBLM_01462 3.3e-161 2.7.1.2 GK ROK family
HELEIBLM_01463 1.6e-202 GK ROK family
HELEIBLM_01464 1.7e-148 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HELEIBLM_01465 1.1e-234 nagA 3.5.1.25 G Amidohydrolase family
HELEIBLM_01466 2.4e-192 G Bacterial extracellular solute-binding protein
HELEIBLM_01467 9.8e-105 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_01468 7.9e-126 G Binding-protein-dependent transport systems inner membrane component
HELEIBLM_01471 3.2e-189 3.2.1.51 GH29 G Alpha-L-fucosidase
HELEIBLM_01472 1e-74 3.6.1.55 F NUDIX domain
HELEIBLM_01473 1.7e-301 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HELEIBLM_01474 8.8e-160 K Psort location Cytoplasmic, score
HELEIBLM_01475 3.5e-286 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HELEIBLM_01476 0.0 smc D Required for chromosome condensation and partitioning
HELEIBLM_01477 1.3e-190 V Acetyltransferase (GNAT) domain
HELEIBLM_01478 4.6e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HELEIBLM_01479 2.6e-138 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HELEIBLM_01480 1.6e-54
HELEIBLM_01481 8.1e-187 galM 5.1.3.3 G Aldose 1-epimerase
HELEIBLM_01482 2e-188 galM 5.1.3.3 G Aldose 1-epimerase
HELEIBLM_01483 2.3e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HELEIBLM_01484 3.6e-174 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HELEIBLM_01485 4.5e-10 tnp3503b 2.7.7.7 L transposition, DNA-mediated
HELEIBLM_01486 2.7e-198 L Transposase and inactivated derivatives IS30 family
HELEIBLM_01487 1.4e-60 L Transposase, Mutator family
HELEIBLM_01488 3.1e-34 L IstB-like ATP binding protein
HELEIBLM_01489 3e-63 E GDSL-like Lipase/Acylhydrolase family
HELEIBLM_01490 1e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_01491 1.4e-251 V ABC-2 family transporter protein
HELEIBLM_01492 1.5e-225 V ABC-2 family transporter protein
HELEIBLM_01493 2.9e-187 V ATPases associated with a variety of cellular activities
HELEIBLM_01494 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HELEIBLM_01495 4e-227 T Histidine kinase
HELEIBLM_01496 2.3e-103 K helix_turn_helix, Lux Regulon
HELEIBLM_01497 2.1e-114 MA20_27875 P Protein of unknown function DUF47
HELEIBLM_01498 3.1e-187 pit P Phosphate transporter family
HELEIBLM_01499 7.8e-249 nplT G Alpha amylase, catalytic domain
HELEIBLM_01500 1.2e-31 EGP Major Facilitator Superfamily
HELEIBLM_01502 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HELEIBLM_01503 8.7e-232 rutG F Permease family
HELEIBLM_01504 3e-161 3.1.3.73 G Phosphoglycerate mutase family
HELEIBLM_01505 1.3e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
HELEIBLM_01506 3.7e-233 EGP Major facilitator Superfamily
HELEIBLM_01509 1.5e-131 S Sulfite exporter TauE/SafE
HELEIBLM_01510 6.6e-11
HELEIBLM_01512 1e-35 feoA P FeoA
HELEIBLM_01513 4.3e-79 S Helix-turn-helix
HELEIBLM_01514 4.6e-200 S Short C-terminal domain
HELEIBLM_01515 9.2e-39
HELEIBLM_01516 2.7e-216
HELEIBLM_01517 4.2e-77 K Psort location Cytoplasmic, score
HELEIBLM_01518 3.2e-282 KLT Protein tyrosine kinase
HELEIBLM_01519 1e-260 EGP Transmembrane secretion effector
HELEIBLM_01520 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
HELEIBLM_01521 2.2e-11
HELEIBLM_01522 2.7e-118 K Bacterial regulatory proteins, tetR family
HELEIBLM_01523 1.7e-216 G Transmembrane secretion effector
HELEIBLM_01524 2.4e-17 K addiction module antidote protein HigA
HELEIBLM_01525 3.7e-243 S HipA-like C-terminal domain
HELEIBLM_01526 1.1e-37 L RelB antitoxin
HELEIBLM_01527 2.9e-51 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HELEIBLM_01528 8.7e-65 S Cupin 2, conserved barrel domain protein
HELEIBLM_01529 2.1e-33 ksgA 2.1.1.182 J Methyltransferase domain
HELEIBLM_01530 7e-60 yccF S Inner membrane component domain
HELEIBLM_01531 3.2e-231 XK27_00240 K Fic/DOC family
HELEIBLM_01532 1.4e-26 2.7.7.7 L Transposase, Mutator family
HELEIBLM_01533 0.0 drrC L ABC transporter
HELEIBLM_01534 2.5e-245 V MatE
HELEIBLM_01535 3.4e-26 S rRNA binding
HELEIBLM_01536 4e-164 K Arac family
HELEIBLM_01537 1.2e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HELEIBLM_01538 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HELEIBLM_01539 7.2e-283 pip 3.4.11.5 S alpha/beta hydrolase fold
HELEIBLM_01540 0.0 tcsS2 T Histidine kinase
HELEIBLM_01541 9e-132 K helix_turn_helix, Lux Regulon
HELEIBLM_01542 0.0 MV MacB-like periplasmic core domain
HELEIBLM_01543 3.7e-144 V ABC transporter, ATP-binding protein
HELEIBLM_01544 1.8e-248 metY 2.5.1.49 E Aminotransferase class-V
HELEIBLM_01545 1.4e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HELEIBLM_01546 4.8e-93 yraN L Belongs to the UPF0102 family
HELEIBLM_01547 1.2e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
HELEIBLM_01548 5.4e-306 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HELEIBLM_01549 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HELEIBLM_01550 6.8e-173 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HELEIBLM_01551 4.3e-110 safC S O-methyltransferase
HELEIBLM_01552 2.8e-147 fmt2 3.2.2.10 S Belongs to the LOG family
HELEIBLM_01553 1.2e-229 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HELEIBLM_01556 1.8e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HELEIBLM_01557 2.1e-123 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HELEIBLM_01558 3.8e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HELEIBLM_01559 2.1e-53
HELEIBLM_01560 8.9e-233 clcA_2 P Voltage gated chloride channel
HELEIBLM_01561 5.8e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HELEIBLM_01562 1.3e-248 rnd 3.1.13.5 J 3'-5' exonuclease
HELEIBLM_01563 1.3e-119 S Protein of unknown function (DUF3000)
HELEIBLM_01564 1.9e-174 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HELEIBLM_01565 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HELEIBLM_01566 8.5e-34
HELEIBLM_01567 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HELEIBLM_01568 1.6e-224 S Peptidase dimerisation domain
HELEIBLM_01569 2.8e-112 metI P Binding-protein-dependent transport system inner membrane component
HELEIBLM_01570 3.9e-218 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HELEIBLM_01571 2.1e-169 metQ P NLPA lipoprotein
HELEIBLM_01572 2.2e-311 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HELEIBLM_01573 3.4e-171 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HELEIBLM_01574 7.4e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HELEIBLM_01575 1.5e-243
HELEIBLM_01576 1.9e-64
HELEIBLM_01577 2.4e-37 uvrA3 L excinuclease ABC
HELEIBLM_01578 1.6e-57 uvrA3 L Psort location Cytoplasmic, score
HELEIBLM_01579 5.8e-125 uvrA3 L Psort location Cytoplasmic, score
HELEIBLM_01580 7.1e-267 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
HELEIBLM_01581 1.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HELEIBLM_01583 9.9e-258 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HELEIBLM_01584 3.7e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HELEIBLM_01585 1.5e-132 3.1.3.85 G Phosphoglycerate mutase family
HELEIBLM_01587 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HELEIBLM_01588 4.2e-228 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HELEIBLM_01589 1.3e-246 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HELEIBLM_01590 1.2e-195 ykiI
HELEIBLM_01591 3.4e-135 V MatE
HELEIBLM_01592 2.7e-18 K Transcriptional regulator
HELEIBLM_01593 4.2e-32 K Transcriptional regulator
HELEIBLM_01594 8.8e-52
HELEIBLM_01596 5.6e-193
HELEIBLM_01597 9.8e-269 S MvaI/BcnI restriction endonuclease family
HELEIBLM_01598 7.7e-239 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HELEIBLM_01599 8.5e-37 KL Type III restriction enzyme res subunit
HELEIBLM_01601 1.4e-39
HELEIBLM_01603 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HELEIBLM_01604 7.5e-126 3.6.1.13 L NUDIX domain
HELEIBLM_01605 2.3e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HELEIBLM_01606 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HELEIBLM_01607 2.9e-121 pdtaR T Response regulator receiver domain protein
HELEIBLM_01609 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
HELEIBLM_01610 3.1e-165 terC P Integral membrane protein, TerC family
HELEIBLM_01611 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HELEIBLM_01612 3.3e-55 2.1.1.80, 3.1.1.61 T Histidine kinase
HELEIBLM_01613 4e-63 K helix_turn_helix, Lux Regulon
HELEIBLM_01615 1e-143 XK27_10205
HELEIBLM_01616 1.4e-73 V ABC transporter
HELEIBLM_01617 2.3e-73 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HELEIBLM_01618 2.3e-252 rpsA J Ribosomal protein S1
HELEIBLM_01619 4.8e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HELEIBLM_01620 8.4e-173 P Zinc-uptake complex component A periplasmic
HELEIBLM_01621 1.6e-163 znuC P ATPases associated with a variety of cellular activities
HELEIBLM_01622 3.1e-137 znuB U ABC 3 transport family
HELEIBLM_01623 1e-90 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HELEIBLM_01624 1.6e-100 carD K CarD-like/TRCF domain
HELEIBLM_01625 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HELEIBLM_01626 5e-128 T Response regulator receiver domain protein
HELEIBLM_01627 6.2e-191 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELEIBLM_01628 1.8e-60 KT Peptidase S24-like
HELEIBLM_01629 3.5e-57 ctsW S Phosphoribosyl transferase domain
HELEIBLM_01630 7.5e-149 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HELEIBLM_01631 3.3e-64 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HELEIBLM_01632 2.9e-266
HELEIBLM_01633 0.0 S Glycosyl transferase, family 2
HELEIBLM_01634 4.7e-56 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HELEIBLM_01635 1e-164 K Cell envelope-related transcriptional attenuator domain
HELEIBLM_01636 0.0 D FtsK/SpoIIIE family
HELEIBLM_01637 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HELEIBLM_01638 6.7e-279 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELEIBLM_01639 1.1e-148 yplQ S Haemolysin-III related
HELEIBLM_01640 5.7e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HELEIBLM_01641 8.9e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HELEIBLM_01642 3.2e-275 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HELEIBLM_01643 1.2e-92
HELEIBLM_01644 1.3e-165 int8 L Phage integrase family
HELEIBLM_01645 8.1e-11
HELEIBLM_01646 7.2e-65
HELEIBLM_01647 1.7e-61 L Belongs to the 'phage' integrase family
HELEIBLM_01650 9.5e-19 S Putative phage holin Dp-1
HELEIBLM_01651 9.3e-194 M Glycosyl hydrolases family 25
HELEIBLM_01657 1.3e-35
HELEIBLM_01659 1.1e-22 ebh 2.1.1.80, 3.1.1.61 S cellulase activity
HELEIBLM_01660 0.0 ebh 2.1.1.80, 3.1.1.61 S cellulase activity
HELEIBLM_01662 3.5e-217 NT phage tail tape measure protein
HELEIBLM_01664 8.9e-61
HELEIBLM_01665 7.5e-107
HELEIBLM_01666 7.1e-66
HELEIBLM_01667 5.3e-41
HELEIBLM_01668 1.8e-50
HELEIBLM_01669 5.5e-20
HELEIBLM_01671 2.3e-77 xkdG S Phage capsid family
HELEIBLM_01672 4.2e-32 S peptidase activity
HELEIBLM_01673 2.4e-80 S Phage portal protein
HELEIBLM_01674 3.3e-305 S Terminase
HELEIBLM_01675 4e-41
HELEIBLM_01677 3.3e-122
HELEIBLM_01678 1.6e-14
HELEIBLM_01682 2.2e-108
HELEIBLM_01685 2.3e-08 E Transcription factor WhiB
HELEIBLM_01688 4e-63
HELEIBLM_01690 1.3e-48 ssb1 L Single-strand binding protein family
HELEIBLM_01692 4.1e-73 recT L RecT family
HELEIBLM_01693 3.3e-82 yqaJ L YqaJ-like viral recombinase domain
HELEIBLM_01698 1.6e-116 K BRO family, N-terminal domain
HELEIBLM_01700 3.4e-47 Q methyltransferase
HELEIBLM_01701 3.2e-19
HELEIBLM_01704 6.6e-11
HELEIBLM_01705 2.5e-08
HELEIBLM_01706 5.1e-46
HELEIBLM_01708 1e-41 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HELEIBLM_01709 4.3e-83
HELEIBLM_01711 1.7e-179 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HELEIBLM_01712 2.4e-101 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HELEIBLM_01713 1.4e-75 divIC D Septum formation initiator
HELEIBLM_01714 1.3e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HELEIBLM_01715 4.9e-173 1.1.1.65 C Aldo/keto reductase family
HELEIBLM_01716 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HELEIBLM_01717 2e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HELEIBLM_01718 1.5e-71 S PIN domain
HELEIBLM_01719 2.5e-47 S RelB antitoxin
HELEIBLM_01720 4.6e-88 2.3.1.183 M Acetyltransferase (GNAT) domain
HELEIBLM_01721 0.0 S Uncharacterised protein family (UPF0182)
HELEIBLM_01722 1.4e-207 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HELEIBLM_01723 3.8e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HELEIBLM_01724 7.9e-100
HELEIBLM_01725 6.7e-232 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HELEIBLM_01726 1.9e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HELEIBLM_01727 2.4e-281 thrC 4.2.3.1 E Threonine synthase N terminus
HELEIBLM_01728 1.6e-205 S Protein of unknown function (DUF1648)
HELEIBLM_01729 1.8e-75 K helix_turn_helix gluconate operon transcriptional repressor
HELEIBLM_01730 1.9e-237 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_01731 2.5e-40 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HELEIBLM_01732 1e-73 S ABC-2 family transporter protein
HELEIBLM_01733 1.9e-119 S ABC-2 family transporter protein
HELEIBLM_01734 7.2e-172 V ATPases associated with a variety of cellular activities
HELEIBLM_01735 1.4e-57 K helix_turn_helix gluconate operon transcriptional repressor
HELEIBLM_01736 1.4e-36 K helix_turn_helix, Lux Regulon
HELEIBLM_01737 1.2e-31 2.7.13.3 T Histidine kinase
HELEIBLM_01738 2e-52 EGP Major facilitator Superfamily
HELEIBLM_01739 3.1e-07 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HELEIBLM_01740 9.1e-113 S Haloacid dehalogenase-like hydrolase
HELEIBLM_01741 3e-307 recN L May be involved in recombinational repair of damaged DNA
HELEIBLM_01742 5.3e-184 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HELEIBLM_01743 1.1e-97
HELEIBLM_01744 2e-138 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HELEIBLM_01746 3.1e-195 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HELEIBLM_01747 7.4e-133 L Tetratricopeptide repeat
HELEIBLM_01748 7.5e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HELEIBLM_01749 2.9e-134 S Putative ABC-transporter type IV
HELEIBLM_01750 8.9e-98 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HELEIBLM_01751 1.3e-55 M1-798 P Rhodanese Homology Domain
HELEIBLM_01752 7.8e-146 moeB 2.7.7.80 H ThiF family
HELEIBLM_01753 1.1e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HELEIBLM_01754 2.1e-28 thiS 2.8.1.10 H ThiS family
HELEIBLM_01755 4e-281 argH 4.3.2.1 E argininosuccinate lyase
HELEIBLM_01756 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HELEIBLM_01757 1.7e-82 argR K Regulates arginine biosynthesis genes
HELEIBLM_01758 8.6e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HELEIBLM_01759 6.6e-248 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HELEIBLM_01760 4.2e-161 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HELEIBLM_01761 7.8e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HELEIBLM_01762 7.9e-202 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HELEIBLM_01763 2.6e-94
HELEIBLM_01764 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HELEIBLM_01765 3.8e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HELEIBLM_01766 3e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HELEIBLM_01767 4.2e-147 cbiQ P Cobalt transport protein
HELEIBLM_01768 4.7e-274 ykoD P ATPases associated with a variety of cellular activities
HELEIBLM_01769 9e-107 ykoE S ABC-type cobalt transport system, permease component
HELEIBLM_01770 2.4e-256 argE E Peptidase dimerisation domain
HELEIBLM_01771 4.2e-107 S Protein of unknown function (DUF3043)
HELEIBLM_01772 1.2e-277 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HELEIBLM_01773 4.7e-140 S Domain of unknown function (DUF4191)
HELEIBLM_01774 5e-281 glnA 6.3.1.2 E glutamine synthetase
HELEIBLM_01775 4.3e-97 uidA 3.2.1.31 G Glycosyl hydrolases family 2, TIM barrel domain
HELEIBLM_01776 1.3e-67 S Membrane transport protein
HELEIBLM_01777 1.3e-88 S Membrane transport protein
HELEIBLM_01778 7e-79 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HELEIBLM_01779 2.5e-84 laaE K Transcriptional regulator PadR-like family
HELEIBLM_01780 4.3e-116 magIII L endonuclease III
HELEIBLM_01781 7.5e-242 vbsD V MatE
HELEIBLM_01782 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HELEIBLM_01783 1.6e-305 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HELEIBLM_01784 1.1e-94 S AAA domain
HELEIBLM_01785 3.4e-132 C FMN binding
HELEIBLM_01786 5.4e-97 effR K helix_turn_helix multiple antibiotic resistance protein
HELEIBLM_01787 3.4e-11 S AAA domain
HELEIBLM_01788 1.5e-189 K helix_turn _helix lactose operon repressor
HELEIBLM_01789 4.5e-161 P Phosphate transporter family
HELEIBLM_01790 7.8e-164 ugpA P Binding-protein-dependent transport system inner membrane component
HELEIBLM_01791 1.2e-141 ugpE G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01792 1.5e-239 ugpB G Bacterial extracellular solute-binding protein
HELEIBLM_01793 7.1e-169 ugpQ 3.1.4.46 C Domain of unknown function
HELEIBLM_01794 7.6e-109 P Protein of unknown function DUF47
HELEIBLM_01795 1.4e-256 S Domain of unknown function (DUF4143)
HELEIBLM_01796 0.0 V FtsX-like permease family
HELEIBLM_01797 3.3e-124 V ABC transporter
HELEIBLM_01798 7.7e-109 K Bacterial regulatory proteins, tetR family
HELEIBLM_01799 9.3e-192 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HELEIBLM_01800 3e-16 K MerR family regulatory protein
HELEIBLM_01801 3.8e-10 K MerR family regulatory protein
HELEIBLM_01802 3.8e-88 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HELEIBLM_01803 2.8e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HELEIBLM_01804 1e-31 S Psort location CytoplasmicMembrane, score
HELEIBLM_01805 8.6e-185 MA20_14895 S Conserved hypothetical protein 698
HELEIBLM_01806 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HELEIBLM_01807 3e-94 tmp1 S Domain of unknown function (DUF4391)
HELEIBLM_01808 1.8e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HELEIBLM_01809 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HELEIBLM_01810 1.6e-79 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HELEIBLM_01811 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HELEIBLM_01812 4.1e-187 yocS S SBF-like CPA transporter family (DUF4137)
HELEIBLM_01814 1.1e-189 ltaE 4.1.2.48 E Beta-eliminating lyase
HELEIBLM_01815 3.2e-209 M Glycosyl transferase 4-like domain
HELEIBLM_01816 1.3e-189 mtnE 2.6.1.83 E Aminotransferase class I and II
HELEIBLM_01817 8.7e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HELEIBLM_01818 2.7e-61 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HELEIBLM_01819 2.1e-137 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HELEIBLM_01820 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HELEIBLM_01821 7.5e-215 I alpha/beta hydrolase fold
HELEIBLM_01822 1.7e-254 Q D-alanine [D-alanyl carrier protein] ligase activity
HELEIBLM_01823 5.3e-108 Q D-alanine [D-alanyl carrier protein] ligase activity
HELEIBLM_01824 5e-99 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HELEIBLM_01825 5e-170 hipA 2.7.11.1 S HipA N-terminal domain
HELEIBLM_01826 1e-120 C Aldo/keto reductase family
HELEIBLM_01827 1.6e-32
HELEIBLM_01828 5.6e-276 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HELEIBLM_01829 3.9e-191 3.3.1.1 H S-adenosyl-L-homocysteine hydrolase, NAD binding domain
HELEIBLM_01830 2.1e-239 ssnA 3.5.4.40 F Amidohydrolase family
HELEIBLM_01831 1.8e-65 MA20_39615 S Cupin superfamily (DUF985)
HELEIBLM_01832 1.1e-126 ET Bacterial periplasmic substrate-binding proteins
HELEIBLM_01833 1.9e-122 E Binding-protein-dependent transport system inner membrane component
HELEIBLM_01834 1.9e-120 glnQ 3.6.3.21 E AAA domain, putative AbiEii toxin, Type IV TA system
HELEIBLM_01835 7.2e-286 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HELEIBLM_01836 5.4e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HELEIBLM_01837 2.7e-233 purD 6.3.4.13 F Belongs to the GARS family
HELEIBLM_01838 2.8e-275 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
HELEIBLM_01839 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HELEIBLM_01840 1.5e-148 P Zinc-uptake complex component A periplasmic
HELEIBLM_01841 4.7e-100 S cobalamin synthesis protein
HELEIBLM_01842 1.9e-28 rpmB J Ribosomal L28 family
HELEIBLM_01843 1.4e-20 rpmG J Ribosomal protein L33
HELEIBLM_01844 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HELEIBLM_01845 4.4e-34 rpmE2 J Ribosomal protein L31
HELEIBLM_01846 1.1e-14 rpmJ J Ribosomal protein L36
HELEIBLM_01847 2.6e-19 J Ribosomal L32p protein family
HELEIBLM_01848 3.2e-27 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HELEIBLM_01849 2.7e-165 ycgR S Predicted permease
HELEIBLM_01850 3.3e-138 S TIGRFAM TIGR03943 family protein
HELEIBLM_01851 3.7e-21 zur P Ferric uptake regulator family
HELEIBLM_01852 1.7e-54 zur P Ferric uptake regulator family
HELEIBLM_01853 1.1e-58
HELEIBLM_01854 2e-46 tetR K Transcriptional regulator C-terminal region
HELEIBLM_01855 1.4e-17 XK27_06785 V ABC transporter
HELEIBLM_01856 3.9e-85 ylbB V FtsX-like permease family
HELEIBLM_01857 1.2e-68 zur P Belongs to the Fur family
HELEIBLM_01858 1.8e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HELEIBLM_01859 7.3e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HELEIBLM_01860 1e-176 adh3 C Zinc-binding dehydrogenase
HELEIBLM_01861 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HELEIBLM_01862 1.4e-252 macB_8 V MacB-like periplasmic core domain
HELEIBLM_01863 1.2e-131 M Conserved repeat domain
HELEIBLM_01864 6.4e-121 V ATPases associated with a variety of cellular activities
HELEIBLM_01866 1.6e-216 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_01867 6.8e-156 K Helix-turn-helix domain, rpiR family
HELEIBLM_01868 0.0 G Alpha-L-arabinofuranosidase C-terminal domain
HELEIBLM_01869 4.7e-28
HELEIBLM_01870 5e-270 pip S YhgE Pip domain protein
HELEIBLM_01871 0.0 pip S YhgE Pip domain protein
HELEIBLM_01872 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HELEIBLM_01873 7.5e-59 S Protein of unknown function (DUF4235)
HELEIBLM_01874 3.5e-134 G Phosphoglycerate mutase family
HELEIBLM_01875 3.6e-246 amyE G Bacterial extracellular solute-binding protein
HELEIBLM_01876 5e-182 K Psort location Cytoplasmic, score
HELEIBLM_01877 7.4e-147 msmF G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01878 1.5e-152 rafG G ABC transporter permease
HELEIBLM_01879 1.6e-101 S Protein of unknown function, DUF624
HELEIBLM_01880 2.3e-255 aroP E aromatic amino acid transport protein AroP K03293
HELEIBLM_01881 6.1e-123 V ABC transporter
HELEIBLM_01882 0.0 V FtsX-like permease family
HELEIBLM_01883 1.3e-266 cycA E Amino acid permease
HELEIBLM_01884 7.8e-78 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HELEIBLM_01885 0.0 lmrA1 V ABC transporter, ATP-binding protein
HELEIBLM_01886 0.0 lmrA2 V ABC transporter transmembrane region
HELEIBLM_01887 2.6e-152 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HELEIBLM_01889 1.5e-181 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HELEIBLM_01890 8.3e-26
HELEIBLM_01891 4.7e-114
HELEIBLM_01892 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HELEIBLM_01893 4.4e-46
HELEIBLM_01894 1.5e-169 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HELEIBLM_01895 7e-262 pepC 3.4.22.40 E Peptidase C1-like family
HELEIBLM_01896 2e-175 appB EP Binding-protein-dependent transport system inner membrane component
HELEIBLM_01897 9.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
HELEIBLM_01898 0.0 oppD P Belongs to the ABC transporter superfamily
HELEIBLM_01899 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HELEIBLM_01901 2.4e-251 EGP Major Facilitator Superfamily
HELEIBLM_01902 4.4e-266 S AAA domain
HELEIBLM_01903 1.5e-58 G domain, Protein
HELEIBLM_01904 2.5e-250 S Domain of unknown function (DUF4143)
HELEIBLM_01905 3.9e-270 S ATPase domain predominantly from Archaea
HELEIBLM_01906 0.0 mdlA2 V ABC transporter
HELEIBLM_01907 2.5e-311 yknV V ABC transporter
HELEIBLM_01908 7.5e-197 S Fic/DOC family
HELEIBLM_01909 5.9e-185 tatD L TatD related DNase
HELEIBLM_01910 0.0 kup P Transport of potassium into the cell
HELEIBLM_01911 1.3e-159 S Glutamine amidotransferase domain
HELEIBLM_01912 1.3e-133 T HD domain
HELEIBLM_01914 2.6e-171 V ABC transporter
HELEIBLM_01915 2.6e-216 V ABC transporter permease
HELEIBLM_01916 0.0 pflA S Protein of unknown function (DUF4012)
HELEIBLM_01917 2.3e-194 I transferase activity, transferring acyl groups other than amino-acyl groups
HELEIBLM_01918 2.5e-52 S Predicted membrane protein (DUF2142)
HELEIBLM_01919 6.2e-145 cobB2 K Sir2 family
HELEIBLM_01920 1e-232 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HELEIBLM_01921 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HELEIBLM_01922 6.6e-09 L Transposase
HELEIBLM_01923 2.9e-154 G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01924 1.1e-143 malC G Binding-protein-dependent transport system inner membrane component
HELEIBLM_01925 4.9e-243 msmE7 G Bacterial extracellular solute-binding protein
HELEIBLM_01926 2.1e-227 nagC GK ROK family
HELEIBLM_01927 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HELEIBLM_01928 3.2e-78 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HELEIBLM_01929 0.0 yjcE P Sodium/hydrogen exchanger family
HELEIBLM_01930 3e-147 ypfH S Phospholipase/Carboxylesterase
HELEIBLM_01931 2.6e-131
HELEIBLM_01932 3.4e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HELEIBLM_01933 4.9e-80
HELEIBLM_01934 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HELEIBLM_01935 2e-16 K helix_turn _helix lactose operon repressor
HELEIBLM_01936 1.8e-84 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HELEIBLM_01937 5e-287 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HELEIBLM_01938 1.1e-204 EGP Major facilitator Superfamily
HELEIBLM_01939 7.5e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HELEIBLM_01940 6.3e-268 KLT Domain of unknown function (DUF4032)
HELEIBLM_01941 1.8e-209 ugpC E Belongs to the ABC transporter superfamily
HELEIBLM_01942 5.9e-219 2.4.1.166 GT2 M Glycosyltransferase like family 2
HELEIBLM_01943 3.7e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HELEIBLM_01945 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HELEIBLM_01946 4.2e-80 nrdI F Probably involved in ribonucleotide reductase function
HELEIBLM_01947 4.1e-43 nrdH O Glutaredoxin
HELEIBLM_01948 2.7e-109 K Helix-turn-helix XRE-family like proteins
HELEIBLM_01949 1.2e-120 S Protein of unknown function (DUF3990)
HELEIBLM_01950 9.2e-107 kcsA U Ion channel
HELEIBLM_01951 1.9e-203 S AAA ATPase domain
HELEIBLM_01952 2.4e-46 3.2.1.21 GH3 G Fibronectin type III-like domain
HELEIBLM_01953 0.0 KLT Protein tyrosine kinase
HELEIBLM_01954 1.2e-129 O Thioredoxin
HELEIBLM_01956 7.7e-211 S G5
HELEIBLM_01957 4.5e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HELEIBLM_01958 1.2e-174 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HELEIBLM_01959 2.1e-106 S LytR cell envelope-related transcriptional attenuator
HELEIBLM_01960 1.4e-275 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HELEIBLM_01961 4.6e-116 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HELEIBLM_01962 0.0
HELEIBLM_01963 0.0 murJ KLT MviN-like protein
HELEIBLM_01964 6.3e-185 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HELEIBLM_01965 1.9e-216 parB K Belongs to the ParB family
HELEIBLM_01966 7.8e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HELEIBLM_01967 5.5e-121 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HELEIBLM_01968 1.1e-92 jag S Putative single-stranded nucleic acids-binding domain
HELEIBLM_01969 5.8e-175 yidC U Membrane protein insertase, YidC Oxa1 family
HELEIBLM_01970 4e-33 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HELEIBLM_01971 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HELEIBLM_01972 4.6e-285 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HELEIBLM_01974 7.6e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HELEIBLM_01975 6.4e-224 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HELEIBLM_01976 8.7e-81 S Protein of unknown function (DUF721)
HELEIBLM_01977 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HELEIBLM_01978 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HELEIBLM_01979 2.1e-81 S Transmembrane domain of unknown function (DUF3566)
HELEIBLM_01980 2.2e-273 S ATPase domain predominantly from Archaea
HELEIBLM_01981 1e-14 K helix_turn _helix lactose operon repressor
HELEIBLM_01982 5.1e-251 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HELEIBLM_01983 3.4e-27 S addiction module toxin, RelE StbE family
HELEIBLM_01984 1.3e-28 relB L RelB antitoxin
HELEIBLM_01985 2.9e-34
HELEIBLM_01987 1.1e-30 L Phage integrase family
HELEIBLM_01990 4.9e-70 cpdB 3.1.3.6, 3.1.4.16 F Calcineurin-like phosphoesterase
HELEIBLM_01991 3.8e-81 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_01992 3.4e-77 phnE 3.6.1.63 U Binding-protein-dependent transport system inner membrane component
HELEIBLM_01993 2e-82 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HELEIBLM_01994 1.8e-114 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HELEIBLM_01995 2.7e-35 K Helix-turn-helix domain, rpiR family
HELEIBLM_01996 3.7e-30 S phosphoglycolate phosphatase activity
HELEIBLM_01997 2.9e-203 S Domain of unknown function (DUF4143)
HELEIBLM_01998 3e-146 S Protein of unknown function DUF45
HELEIBLM_01999 5e-92 K FCD
HELEIBLM_02000 3.7e-215 EG GntP family permease
HELEIBLM_02001 4.3e-87 gntK 1.1.1.343, 1.1.1.44, 2.7.1.12, 2.7.1.71 F Shikimate kinase
HELEIBLM_02002 4e-151 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
HELEIBLM_02003 7.3e-83 dps P Belongs to the Dps family
HELEIBLM_02004 1e-235 ytfL P Transporter associated domain
HELEIBLM_02005 2.8e-202 S AAA ATPase domain
HELEIBLM_02006 7.9e-72 V Forkhead associated domain
HELEIBLM_02007 1.6e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HELEIBLM_02008 1.1e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HELEIBLM_02009 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HELEIBLM_02010 8.1e-238 yhjX EGP Major facilitator Superfamily
HELEIBLM_02011 4.5e-148 S Domain of unknown function (DUF4143)
HELEIBLM_02012 9e-128 S Metallo-beta-lactamase domain protein
HELEIBLM_02013 4.7e-26 L Transposase
HELEIBLM_02014 2.2e-60 L Transposase
HELEIBLM_02015 4.8e-84 V ABC-2 type transporter
HELEIBLM_02016 7.2e-85 V ABC transporter, ATP-binding protein
HELEIBLM_02017 6.8e-41 L PFAM Integrase catalytic
HELEIBLM_02018 4.9e-59 L Transposase
HELEIBLM_02019 1.7e-232 S AAA domain
HELEIBLM_02020 2.9e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HELEIBLM_02021 2e-25 trxB1 1.8.1.9 C Thioredoxin domain
HELEIBLM_02022 4.4e-191 oppA5 E family 5
HELEIBLM_02023 1.9e-122 appB P PFAM binding-protein-dependent transport systems inner membrane component
HELEIBLM_02024 2.5e-89 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HELEIBLM_02025 5.4e-153 P Belongs to the ABC transporter superfamily
HELEIBLM_02026 9.9e-37 ybfG M Domain of unknown function (DUF1906)
HELEIBLM_02028 7.2e-33 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HELEIBLM_02029 4.2e-171 L ATPase involved in DNA repair
HELEIBLM_02031 1.2e-113
HELEIBLM_02032 1.3e-36 S Sigma-70, region 4
HELEIBLM_02034 0.0 M Domain of unknown function (DUF1906)
HELEIBLM_02035 2.7e-12
HELEIBLM_02036 2.5e-155 ybfG M Domain of unknown function (DUF1906)
HELEIBLM_02038 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HELEIBLM_02039 0.0 yjjP S Threonine/Serine exporter, ThrE
HELEIBLM_02040 1.8e-298 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HELEIBLM_02041 5.7e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HELEIBLM_02042 1e-123 S Amidohydrolase family
HELEIBLM_02043 2.1e-166 S Amidohydrolase family
HELEIBLM_02044 6.3e-199 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HELEIBLM_02045 3.9e-21 S Protein of unknown function (DUF3073)
HELEIBLM_02046 2.3e-105 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HELEIBLM_02047 5.6e-206 2.7.13.3 T Histidine kinase
HELEIBLM_02048 4.5e-234 EGP Major Facilitator Superfamily
HELEIBLM_02049 7.5e-76 I Sterol carrier protein
HELEIBLM_02050 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HELEIBLM_02051 1.7e-31
HELEIBLM_02052 2.9e-125 gluP 3.4.21.105 S Rhomboid family
HELEIBLM_02053 1.3e-79 crgA D Involved in cell division
HELEIBLM_02054 1.7e-108 S Bacterial protein of unknown function (DUF881)
HELEIBLM_02055 5.2e-234 srtA 3.4.22.70 M Sortase family
HELEIBLM_02056 1.1e-118 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HELEIBLM_02057 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HELEIBLM_02058 1.3e-171 T Protein tyrosine kinase
HELEIBLM_02059 1e-260 pbpA M penicillin-binding protein
HELEIBLM_02060 1.2e-251 rodA D Belongs to the SEDS family
HELEIBLM_02061 1.9e-239 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HELEIBLM_02062 8e-59 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HELEIBLM_02063 2.6e-129 fhaA T Protein of unknown function (DUF2662)
HELEIBLM_02064 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HELEIBLM_02065 3.1e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
HELEIBLM_02066 9.8e-148 yddG EG EamA-like transporter family
HELEIBLM_02067 3.5e-231 S Putative esterase
HELEIBLM_02068 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HELEIBLM_02069 2.8e-190 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HELEIBLM_02070 2e-129 S Pyridoxamine 5'-phosphate oxidase
HELEIBLM_02071 4.8e-79 S Fic/DOC family
HELEIBLM_02072 5.7e-172 L Psort location Cytoplasmic, score
HELEIBLM_02073 1.2e-106 S KR domain
HELEIBLM_02074 8.2e-16 tnp7109-2 L Transposase, Mutator family
HELEIBLM_02075 1.5e-36
HELEIBLM_02076 8.1e-21
HELEIBLM_02077 2.2e-20 L Phage integrase family
HELEIBLM_02078 9.2e-47 L Transposase and inactivated derivatives IS30 family
HELEIBLM_02079 2.9e-12
HELEIBLM_02080 2.6e-44 V efflux transmembrane transporter activity
HELEIBLM_02081 1.6e-199 S Psort location Cytoplasmic, score 7.50
HELEIBLM_02082 2.4e-117 S AAA ATPase domain
HELEIBLM_02083 1.3e-259 EGP Major facilitator Superfamily
HELEIBLM_02084 5.4e-216 mntH P H( )-stimulated, divalent metal cation uptake system
HELEIBLM_02085 5.7e-135 L Protein of unknown function (DUF1524)
HELEIBLM_02086 1.8e-125 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HELEIBLM_02087 6e-81 ganB 3.2.1.89 G Glycosyl hydrolase family 53
HELEIBLM_02088 3.7e-170 K helix_turn _helix lactose operon repressor
HELEIBLM_02090 1.4e-26 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HELEIBLM_02091 2e-25
HELEIBLM_02092 4.7e-101 V ABC transporter
HELEIBLM_02093 1.1e-241 XK27_10205
HELEIBLM_02094 2.2e-19 S Bacteriocin (Lactococcin_972)
HELEIBLM_02095 4.3e-41 K helix_turn_helix, Lux Regulon
HELEIBLM_02096 9.1e-101 2.7.13.3 T Histidine kinase
HELEIBLM_02097 1.5e-247 araE EGP Major facilitator Superfamily
HELEIBLM_02098 1.3e-124 cydD V ABC transporter transmembrane region
HELEIBLM_02099 1.2e-58 cydD V ABC transporter transmembrane region
HELEIBLM_02100 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HELEIBLM_02101 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HELEIBLM_02102 1.1e-143 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HELEIBLM_02103 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HELEIBLM_02104 7.7e-255 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HELEIBLM_02105 1.2e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HELEIBLM_02106 5.5e-233 S peptidyl-serine autophosphorylation
HELEIBLM_02107 9.4e-92 ywrO 1.6.5.2 S Flavodoxin-like fold
HELEIBLM_02108 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HELEIBLM_02109 4.5e-76 F Nucleoside 2-deoxyribosyltransferase
HELEIBLM_02110 4.1e-10 K Acetyltransferase (GNAT) domain
HELEIBLM_02112 2.1e-186 S Endonuclease/Exonuclease/phosphatase family
HELEIBLM_02113 3.1e-11 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HELEIBLM_02114 6.4e-08 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HELEIBLM_02115 2.3e-223 aspB E Aminotransferase class-V
HELEIBLM_02116 7.2e-200 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HELEIBLM_02117 6.4e-85 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HELEIBLM_02118 2e-35 XK27_03610 K Acetyltransferase (GNAT) domain
HELEIBLM_02119 1.1e-33
HELEIBLM_02120 2.4e-78 S PFAM Uncharacterised protein family UPF0150
HELEIBLM_02121 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HELEIBLM_02122 1.1e-211 K WYL domain
HELEIBLM_02123 1.1e-144 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HELEIBLM_02124 1.7e-248 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HELEIBLM_02125 9.2e-152 map 3.4.11.18 E Methionine aminopeptidase
HELEIBLM_02126 1.5e-98 S Short repeat of unknown function (DUF308)
HELEIBLM_02127 0.0 pepO 3.4.24.71 O Peptidase family M13
HELEIBLM_02128 3.9e-51 L Single-strand binding protein family
HELEIBLM_02129 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HELEIBLM_02130 1.6e-302 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HELEIBLM_02131 3.6e-236
HELEIBLM_02132 5.3e-159 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HELEIBLM_02133 3.8e-213 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HELEIBLM_02134 6.3e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HELEIBLM_02135 3.3e-37 yajC U Preprotein translocase subunit
HELEIBLM_02136 6.8e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HELEIBLM_02137 5.2e-89 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HELEIBLM_02138 1.1e-96 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HELEIBLM_02139 3.4e-127 yebC K transcriptional regulatory protein
HELEIBLM_02140 7.7e-111 hit 2.7.7.53 FG HIT domain
HELEIBLM_02141 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HELEIBLM_02145 2.2e-162 S PAC2 family
HELEIBLM_02146 6.5e-154 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HELEIBLM_02147 7.3e-157 G Fructosamine kinase
HELEIBLM_02148 2.8e-210 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HELEIBLM_02149 6.7e-180 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HELEIBLM_02150 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HELEIBLM_02151 5.7e-200 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HELEIBLM_02152 6.4e-217 brnQ U Component of the transport system for branched-chain amino acids
HELEIBLM_02153 1.4e-216 mepA_6 V MatE
HELEIBLM_02154 8.5e-250 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HELEIBLM_02155 8.2e-162 S Sucrose-6F-phosphate phosphohydrolase
HELEIBLM_02156 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HELEIBLM_02157 2.5e-34 secG U Preprotein translocase SecG subunit
HELEIBLM_02158 9.5e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HELEIBLM_02159 1.1e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HELEIBLM_02160 1.2e-169 whiA K May be required for sporulation
HELEIBLM_02161 3e-184 rapZ S Displays ATPase and GTPase activities
HELEIBLM_02162 1.9e-186 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HELEIBLM_02163 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HELEIBLM_02164 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HELEIBLM_02165 7.3e-30 S Psort location Cytoplasmic, score 8.87
HELEIBLM_02166 0.0 S Psort location Cytoplasmic, score 8.87
HELEIBLM_02167 5.6e-105 S Domain of unknown function (DUF4194)
HELEIBLM_02168 2.5e-292 S Psort location Cytoplasmic, score 8.87
HELEIBLM_02169 3.9e-87 macB V ATPases associated with a variety of cellular activities
HELEIBLM_02170 4.3e-17 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
HELEIBLM_02171 2.1e-38 G ATPases associated with a variety of cellular activities
HELEIBLM_02172 4e-32 S Zincin-like metallopeptidase
HELEIBLM_02173 8.2e-162 2.1.1.72 S Protein conserved in bacteria
HELEIBLM_02174 4.9e-128 yueD S Enoyl-(Acyl carrier protein) reductase
HELEIBLM_02175 1.9e-300 ybiT S ABC transporter
HELEIBLM_02176 2.1e-118 S Protein of unknown function (DUF969)
HELEIBLM_02177 7.5e-164 S Protein of unknown function (DUF979)
HELEIBLM_02178 6.3e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HELEIBLM_02179 1.6e-293 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HELEIBLM_02180 2.2e-69 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HELEIBLM_02181 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HELEIBLM_02182 3.9e-75 3.5.1.124 S DJ-1/PfpI family
HELEIBLM_02183 1.6e-221 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HELEIBLM_02184 2.1e-169 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HELEIBLM_02185 5.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HELEIBLM_02186 1.9e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HELEIBLM_02187 7.4e-139 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HELEIBLM_02188 6e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
HELEIBLM_02189 1.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HELEIBLM_02190 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HELEIBLM_02191 1.5e-70
HELEIBLM_02192 2.6e-208 guaB 1.1.1.205 F IMP dehydrogenase family protein
HELEIBLM_02193 1.9e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HELEIBLM_02194 9.2e-255 G ABC transporter substrate-binding protein
HELEIBLM_02195 1.3e-104 M Peptidase family M23
HELEIBLM_02197 1.2e-120 K helix_turn_helix, Lux Regulon
HELEIBLM_02198 3.6e-238 T Histidine kinase
HELEIBLM_02200 4.4e-59
HELEIBLM_02201 2e-139
HELEIBLM_02202 1.9e-142 S ABC-2 family transporter protein
HELEIBLM_02203 6.3e-199 V AAA domain, putative AbiEii toxin, Type IV TA system
HELEIBLM_02204 1.9e-46 L PFAM Relaxase mobilization nuclease family protein
HELEIBLM_02205 6.9e-24 L transposase and inactivated derivatives, IS30 family
HELEIBLM_02206 6.5e-110 L Transposase and inactivated derivatives IS30 family
HELEIBLM_02207 1.4e-20
HELEIBLM_02209 5.5e-56 S Fic/DOC family
HELEIBLM_02212 6.2e-11 2.7.11.1 S HipA-like C-terminal domain
HELEIBLM_02213 1.9e-51 xerH L Phage integrase family
HELEIBLM_02215 1.2e-194 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HELEIBLM_02216 7.8e-97 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HELEIBLM_02217 1.4e-150 yeaZ 2.3.1.234 O Glycoprotease family
HELEIBLM_02218 4.8e-102 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HELEIBLM_02219 6e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
HELEIBLM_02220 2.4e-248 comE S Competence protein
HELEIBLM_02221 7e-58 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HELEIBLM_02222 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HELEIBLM_02223 4.6e-150 ET Bacterial periplasmic substrate-binding proteins
HELEIBLM_02224 6.3e-171 corA P CorA-like Mg2+ transporter protein
HELEIBLM_02225 5.2e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HELEIBLM_02226 4.9e-235 L ribosomal rna small subunit methyltransferase
HELEIBLM_02227 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HELEIBLM_02228 5.4e-159 EG EamA-like transporter family
HELEIBLM_02229 5.2e-88
HELEIBLM_02230 2.7e-122 T PhoQ Sensor
HELEIBLM_02231 1e-98 T Transcriptional regulatory protein, C terminal
HELEIBLM_02232 1.8e-89
HELEIBLM_02233 6.9e-56 spaG S Lantibiotic protection ABC transporter permease subunit, MutG family
HELEIBLM_02234 4.4e-63 S ABC-2 family transporter protein
HELEIBLM_02235 1.5e-91 mutF V ABC transporter ATP-binding
HELEIBLM_02236 3.6e-38 V ABC-2 family transporter protein
HELEIBLM_02237 2.1e-19 L Helix-turn-helix domain
HELEIBLM_02238 3.5e-54
HELEIBLM_02239 1.2e-55
HELEIBLM_02240 1.3e-15 L Phage integrase family
HELEIBLM_02241 3.6e-101 V ATPases associated with a variety of cellular activities
HELEIBLM_02242 9.9e-171
HELEIBLM_02243 5e-32
HELEIBLM_02244 2.1e-19 L Helix-turn-helix domain
HELEIBLM_02245 2.7e-123 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
HELEIBLM_02246 3.5e-137 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
HELEIBLM_02247 1.8e-57 G Bacterial extracellular solute-binding protein
HELEIBLM_02248 4.4e-39 G Bacterial extracellular solute-binding protein
HELEIBLM_02249 2.5e-124 G Bacterial extracellular solute-binding protein
HELEIBLM_02250 2.2e-20 G Bacterial extracellular solute-binding protein
HELEIBLM_02251 4.3e-40 G Bacterial extracellular solute-binding protein
HELEIBLM_02252 7.9e-37 G Bacterial extracellular solute-binding protein
HELEIBLM_02253 2.3e-226 G Bacterial extracellular solute-binding protein
HELEIBLM_02254 3.6e-205 G Glycosyl hydrolase family 20, domain 2
HELEIBLM_02255 2e-94 M1-431 S Protein of unknown function (DUF1706)
HELEIBLM_02256 6.1e-128 L Helix-turn-helix domain
HELEIBLM_02257 9.9e-41 L Resolvase, N terminal domain
HELEIBLM_02258 1.1e-210 phoN I PAP2 superfamily
HELEIBLM_02259 3.3e-115 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HELEIBLM_02260 1.1e-75 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HELEIBLM_02261 6.1e-102 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HELEIBLM_02262 1.8e-09 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HELEIBLM_02263 2e-202 G Bacterial extracellular solute-binding protein
HELEIBLM_02264 3.6e-128 ugpE G Binding-protein-dependent transport system inner membrane component
HELEIBLM_02265 9.9e-132 ugpA P Binding-protein-dependent transport system inner membrane component
HELEIBLM_02266 8e-159 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HELEIBLM_02267 4.3e-157 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HELEIBLM_02268 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HELEIBLM_02269 2.6e-74 2.3.1.57 K Acetyltransferase (GNAT) domain
HELEIBLM_02270 2.6e-157 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HELEIBLM_02271 3.4e-23 S Domain of unknown function (DUF4190)
HELEIBLM_02272 1.3e-72 tnp3512a L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)