ORF_ID e_value Gene_name EC_number CAZy COGs Description
KPPHDEDB_00001 1.4e-80 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
KPPHDEDB_00002 1.1e-21 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
KPPHDEDB_00003 5.4e-92 uhpT EGP Major facilitator Superfamily
KPPHDEDB_00004 1.1e-115 P VTC domain
KPPHDEDB_00005 2.3e-111 S Domain of unknown function (DUF4956)
KPPHDEDB_00006 0.0 yliE T Putative diguanylate phosphodiesterase
KPPHDEDB_00007 1.7e-31 L Transposase
KPPHDEDB_00009 1.2e-154 cbiO V ATPases associated with a variety of cellular activities
KPPHDEDB_00010 1.2e-166 lanT 3.6.3.27 V ABC transporter
KPPHDEDB_00011 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPPHDEDB_00012 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KPPHDEDB_00013 1e-246 pbuO S Permease family
KPPHDEDB_00014 6.1e-138 3.2.1.8 S alpha beta
KPPHDEDB_00015 3.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPPHDEDB_00016 1.1e-33 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPPHDEDB_00017 4.1e-187 T Forkhead associated domain
KPPHDEDB_00018 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
KPPHDEDB_00019 6e-31
KPPHDEDB_00020 1e-92 flgA NO SAF
KPPHDEDB_00021 2.5e-31 fmdB S Putative regulatory protein
KPPHDEDB_00022 1.5e-119 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
KPPHDEDB_00023 3.9e-127 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
KPPHDEDB_00024 3.3e-187
KPPHDEDB_00025 6.7e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPPHDEDB_00026 4.7e-42 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KPPHDEDB_00030 4.1e-25 rpmG J Ribosomal protein L33
KPPHDEDB_00031 2.3e-218 murB 1.3.1.98 M Cell wall formation
KPPHDEDB_00032 4.4e-267 E aromatic amino acid transport protein AroP K03293
KPPHDEDB_00033 1.7e-59 fdxA C 4Fe-4S binding domain
KPPHDEDB_00034 1.3e-213 dapC E Aminotransferase class I and II
KPPHDEDB_00035 5.1e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPPHDEDB_00038 8.7e-187 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPPHDEDB_00039 2.1e-109 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
KPPHDEDB_00040 2.7e-108
KPPHDEDB_00041 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KPPHDEDB_00042 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPPHDEDB_00043 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
KPPHDEDB_00044 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KPPHDEDB_00045 2.8e-224 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KPPHDEDB_00046 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPPHDEDB_00047 7.9e-77 ywiC S YwiC-like protein
KPPHDEDB_00048 3.4e-143 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KPPHDEDB_00049 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
KPPHDEDB_00050 1.1e-115 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPPHDEDB_00051 1.2e-115 rplD J Forms part of the polypeptide exit tunnel
KPPHDEDB_00052 3.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPPHDEDB_00053 8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPPHDEDB_00054 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPPHDEDB_00055 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPPHDEDB_00056 2.4e-102 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPPHDEDB_00057 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPPHDEDB_00058 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
KPPHDEDB_00059 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPPHDEDB_00060 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPPHDEDB_00061 1.8e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPPHDEDB_00062 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPPHDEDB_00063 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPPHDEDB_00064 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPPHDEDB_00065 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPPHDEDB_00066 2.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPPHDEDB_00067 1.5e-95 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPPHDEDB_00068 9.2e-26 rpmD J Ribosomal protein L30p/L7e
KPPHDEDB_00069 1.1e-75 rplO J binds to the 23S rRNA
KPPHDEDB_00070 7.6e-247 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPPHDEDB_00071 6.5e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPPHDEDB_00072 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPPHDEDB_00073 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KPPHDEDB_00074 4.7e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPPHDEDB_00075 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPPHDEDB_00076 2e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPPHDEDB_00077 7.7e-62 rplQ J Ribosomal protein L17
KPPHDEDB_00078 4.1e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPPHDEDB_00079 5.1e-62 S N-methyltransferase activity
KPPHDEDB_00080 5.3e-43 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_00082 6e-14
KPPHDEDB_00084 3.8e-27 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KPPHDEDB_00086 4.4e-119 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
KPPHDEDB_00088 1.1e-08 rplV S The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPPHDEDB_00091 1.9e-65 L Transposase IS200 like
KPPHDEDB_00092 1.1e-132 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_00106 6.7e-26 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KPPHDEDB_00107 1.3e-07 S Antitoxin component of a toxin-antitoxin (TA) module
KPPHDEDB_00108 2e-104
KPPHDEDB_00109 1.3e-12 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.5.5 HJ ligase activity
KPPHDEDB_00110 2.4e-87 S AAA domain, putative AbiEii toxin, Type IV TA system
KPPHDEDB_00111 3.2e-26
KPPHDEDB_00113 1.9e-67
KPPHDEDB_00114 3.7e-10 S Domain of unknown function (DUF3841)
KPPHDEDB_00115 0.0 V Type II restriction enzyme, methylase subunits
KPPHDEDB_00126 6.1e-179 2.1.1.113 L Belongs to the N(4) N(6)-methyltransferase family
KPPHDEDB_00127 7.9e-19
KPPHDEDB_00133 6.8e-92 S N-methyltransferase activity
KPPHDEDB_00135 1.7e-75 int L Phage integrase, N-terminal SAM-like domain
KPPHDEDB_00136 5.7e-84 L DNA integration
KPPHDEDB_00137 7.6e-11
KPPHDEDB_00138 4.9e-41 3.4.22.70 M Sortase family
KPPHDEDB_00139 1.1e-47 L helicase
KPPHDEDB_00140 2e-222 L helicase
KPPHDEDB_00141 1.9e-47 S Domain of unknown function (DUF4391)
KPPHDEDB_00144 6.8e-98 K Helix-turn-helix domain protein
KPPHDEDB_00145 2.2e-112 mod 2.1.1.72 L COG2189 Adenine specific DNA methylase Mod
KPPHDEDB_00146 7.4e-45 2.1.1.72 L DNA methylase
KPPHDEDB_00147 0.0 res 3.1.21.5 V Type III restriction enzyme, res subunit
KPPHDEDB_00148 1.6e-07 FG adenosine 5'-monophosphoramidase activity
KPPHDEDB_00149 3.3e-64 S MTH538 TIR-like domain (DUF1863)
KPPHDEDB_00150 2.8e-27 J tRNA 5'-leader removal
KPPHDEDB_00151 3.5e-113 L PFAM Integrase catalytic
KPPHDEDB_00152 1.9e-128 L IstB-like ATP binding protein
KPPHDEDB_00153 1e-16
KPPHDEDB_00157 4.9e-45 ytrE_1 3.6.3.21 V ABC transporter
KPPHDEDB_00158 2.7e-22 V efflux transmembrane transporter activity
KPPHDEDB_00159 2.8e-71 T response regulator
KPPHDEDB_00161 2.4e-59
KPPHDEDB_00162 5.8e-112 K helix_turn_helix, mercury resistance
KPPHDEDB_00163 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
KPPHDEDB_00164 4.2e-139 S Bacterial protein of unknown function (DUF881)
KPPHDEDB_00165 1.2e-28 sbp S Protein of unknown function (DUF1290)
KPPHDEDB_00166 3.5e-124 S Bacterial protein of unknown function (DUF881)
KPPHDEDB_00167 6e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPPHDEDB_00168 2.1e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
KPPHDEDB_00169 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
KPPHDEDB_00170 2.3e-103 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
KPPHDEDB_00171 7.6e-185 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPPHDEDB_00172 6.2e-157 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KPPHDEDB_00173 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KPPHDEDB_00174 6.5e-133 S SOS response associated peptidase (SRAP)
KPPHDEDB_00175 1.5e-152 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KPPHDEDB_00176 1.2e-255 mmuP E amino acid
KPPHDEDB_00177 3e-89 EGP Major facilitator Superfamily
KPPHDEDB_00178 6e-188 V VanZ like family
KPPHDEDB_00179 2.5e-49 cefD 5.1.1.17 E Aminotransferase, class V
KPPHDEDB_00180 1.3e-90 MA20_25245 K FR47-like protein
KPPHDEDB_00181 8.4e-27 S Uncharacterized protein conserved in bacteria (DUF2316)
KPPHDEDB_00182 1.6e-99 S Acetyltransferase (GNAT) domain
KPPHDEDB_00183 7.6e-10 L Transposase DDE domain
KPPHDEDB_00184 3.4e-13 G Bacterial extracellular solute-binding protein
KPPHDEDB_00185 1.6e-150 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00186 3.9e-152 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00191 3.7e-38
KPPHDEDB_00192 9e-126 KL Superfamily II DNA RNA helicases, SNF2 family
KPPHDEDB_00194 1.1e-08
KPPHDEDB_00195 2.3e-133 pgp 3.1.3.18 S HAD-hyrolase-like
KPPHDEDB_00196 1.1e-61 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KPPHDEDB_00197 0.0 helY L DEAD DEAH box helicase
KPPHDEDB_00198 6.6e-48
KPPHDEDB_00199 0.0 pafB K WYL domain
KPPHDEDB_00200 3.8e-295 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
KPPHDEDB_00202 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
KPPHDEDB_00203 7.7e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPPHDEDB_00204 3.9e-160 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KPPHDEDB_00205 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPPHDEDB_00206 1.6e-177 EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00207 5.1e-133 appC EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00208 2e-185 EGP Major facilitator Superfamily
KPPHDEDB_00209 8.9e-264 glnA2 6.3.1.2 E glutamine synthetase
KPPHDEDB_00210 1.5e-20 S Uncharacterized protein conserved in bacteria (DUF2252)
KPPHDEDB_00211 6.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
KPPHDEDB_00212 2e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPPHDEDB_00213 5e-97
KPPHDEDB_00214 6e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
KPPHDEDB_00215 1.2e-219 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPPHDEDB_00216 1.6e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KPPHDEDB_00217 2.7e-269 2.7.1.17 GH19 G FGGY family of carbohydrate kinases, N-terminal domain
KPPHDEDB_00218 5.5e-155 yvgN 1.1.1.346 S Aldo/keto reductase family
KPPHDEDB_00219 2.5e-269 pip S YhgE Pip domain protein
KPPHDEDB_00220 0.0 pip S YhgE Pip domain protein
KPPHDEDB_00221 2.7e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
KPPHDEDB_00222 4.9e-58 S Protein of unknown function (DUF4235)
KPPHDEDB_00223 4.2e-135 G Phosphoglycerate mutase family
KPPHDEDB_00224 5.3e-245 amyE G Bacterial extracellular solute-binding protein
KPPHDEDB_00225 1.1e-181 K Psort location Cytoplasmic, score
KPPHDEDB_00226 2e-147 msmF G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00227 3.4e-152 rafG G ABC transporter permease
KPPHDEDB_00228 1.9e-104 S Protein of unknown function, DUF624
KPPHDEDB_00229 1.3e-18 S COG0433 Predicted ATPase
KPPHDEDB_00230 7.7e-24 dnaN 2.7.7.7 L DNA-directed DNA polymerase activity
KPPHDEDB_00231 7.7e-24 dnaN 2.7.7.7 L DNA-directed DNA polymerase activity
KPPHDEDB_00232 1.3e-18 S COG0433 Predicted ATPase
KPPHDEDB_00233 2.5e-58
KPPHDEDB_00234 2.3e-164 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KPPHDEDB_00235 5.8e-222 nagC GK ROK family
KPPHDEDB_00236 2.9e-243 msmE7 G Bacterial extracellular solute-binding protein
KPPHDEDB_00237 2.5e-140 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00238 2.9e-154 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00239 6.8e-09 L Transposase
KPPHDEDB_00240 3.1e-41 scrT G Transporter major facilitator family protein
KPPHDEDB_00241 1.6e-239 yhjE EGP Sugar (and other) transporter
KPPHDEDB_00243 7.1e-113 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPPHDEDB_00245 3.2e-158 S Fic/DOC family
KPPHDEDB_00246 3.5e-244 S HipA-like C-terminal domain
KPPHDEDB_00248 1.5e-73
KPPHDEDB_00249 1.3e-93 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPPHDEDB_00250 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPPHDEDB_00251 6.1e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KPPHDEDB_00252 5.1e-47 S Domain of unknown function (DUF4193)
KPPHDEDB_00253 3e-177 S Protein of unknown function (DUF3071)
KPPHDEDB_00254 4.6e-238 S Type I phosphodiesterase / nucleotide pyrophosphatase
KPPHDEDB_00255 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KPPHDEDB_00256 3.8e-137 KT RESPONSE REGULATOR receiver
KPPHDEDB_00257 0.0 lhr L DEAD DEAH box helicase
KPPHDEDB_00258 5.2e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPPHDEDB_00259 1.7e-197 G Major Facilitator Superfamily
KPPHDEDB_00260 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KPPHDEDB_00261 5.7e-189 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPPHDEDB_00262 7.6e-123
KPPHDEDB_00263 2.4e-190 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
KPPHDEDB_00264 0.0 pknL 2.7.11.1 KLT PASTA
KPPHDEDB_00265 1.7e-128 plsC2 2.3.1.51 I Phosphate acyltransferases
KPPHDEDB_00266 2.6e-75
KPPHDEDB_00267 7.4e-173 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPPHDEDB_00268 2.6e-64 E GDSL-like Lipase/Acylhydrolase family
KPPHDEDB_00269 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPPHDEDB_00270 3.7e-109 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPPHDEDB_00271 3.1e-99 recX S Modulates RecA activity
KPPHDEDB_00272 2.6e-198 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPPHDEDB_00273 5.3e-39 S Protein of unknown function (DUF3046)
KPPHDEDB_00274 1.2e-80 K Helix-turn-helix XRE-family like proteins
KPPHDEDB_00275 1.8e-90 cinA 3.5.1.42 S Belongs to the CinA family
KPPHDEDB_00276 1.3e-111 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPPHDEDB_00277 0.0 V ABC transporter transmembrane region
KPPHDEDB_00278 2.6e-282 V ABC transporter, ATP-binding protein
KPPHDEDB_00279 5.1e-67 K MarR family
KPPHDEDB_00280 0.0 ftsK D FtsK SpoIIIE family protein
KPPHDEDB_00281 1.7e-136 fic D Fic/DOC family
KPPHDEDB_00282 1.7e-182 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPPHDEDB_00283 4.5e-277 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPPHDEDB_00284 1.4e-146 tnp3512a L Transposase
KPPHDEDB_00285 4.1e-15 tnp7109-2 L Transposase, Mutator family
KPPHDEDB_00286 7.7e-22 tnp7109-2 L Transposase, Mutator family
KPPHDEDB_00287 4.8e-52 tnp7109-2 L PFAM Transposase, Mutator family
KPPHDEDB_00288 3.4e-29 tnp3512a L Transposase
KPPHDEDB_00289 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPPHDEDB_00290 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPPHDEDB_00291 1.5e-110 nusG K Participates in transcription elongation, termination and antitermination
KPPHDEDB_00292 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPPHDEDB_00294 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
KPPHDEDB_00295 4.8e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPPHDEDB_00296 2.9e-304 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPPHDEDB_00297 8.8e-40 rpmA J Ribosomal L27 protein
KPPHDEDB_00298 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KPPHDEDB_00299 0.0 rne 3.1.26.12 J Ribonuclease E/G family
KPPHDEDB_00300 8e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
KPPHDEDB_00301 6.1e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
KPPHDEDB_00302 7.2e-77 fucU 5.1.3.29 G RbsD / FucU transport protein family
KPPHDEDB_00303 7.1e-149 S Amidohydrolase
KPPHDEDB_00304 3.2e-202 fucP G Major Facilitator Superfamily
KPPHDEDB_00305 5.6e-141 IQ KR domain
KPPHDEDB_00306 1.4e-245 4.2.1.68 M Enolase C-terminal domain-like
KPPHDEDB_00307 1.5e-181 K Bacterial regulatory proteins, lacI family
KPPHDEDB_00308 9e-254 V Efflux ABC transporter, permease protein
KPPHDEDB_00309 1.7e-124 V ATPases associated with a variety of cellular activities
KPPHDEDB_00311 9.7e-17 S Protein of unknown function (DUF1778)
KPPHDEDB_00312 3e-08 K Acetyltransferase (GNAT) family
KPPHDEDB_00313 3.6e-31 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KPPHDEDB_00314 5.7e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KPPHDEDB_00315 5.4e-206 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPPHDEDB_00316 3e-232 hom 1.1.1.3 E Homoserine dehydrogenase
KPPHDEDB_00317 1.2e-294 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPPHDEDB_00318 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KPPHDEDB_00319 5.2e-110 K helix_turn _helix lactose operon repressor
KPPHDEDB_00320 2.4e-160 G Bacterial extracellular solute-binding protein
KPPHDEDB_00321 1.3e-134 malC P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00322 3.1e-122 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00323 0.0 3.2.1.25 G beta-mannosidase
KPPHDEDB_00324 3.3e-192 bglA 3.2.1.21 G Glycosyl hydrolase family 1
KPPHDEDB_00325 7.3e-121 K Bacterial regulatory proteins, tetR family
KPPHDEDB_00326 3.5e-142 G Transmembrane secretion effector
KPPHDEDB_00327 4.7e-171 K LysR substrate binding domain protein
KPPHDEDB_00328 3.9e-245 patB 4.4.1.8 E Aminotransferase, class I II
KPPHDEDB_00329 4.1e-253 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPPHDEDB_00330 8.4e-254 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
KPPHDEDB_00331 4.1e-206 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
KPPHDEDB_00332 3.5e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPPHDEDB_00333 4.3e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPPHDEDB_00334 1.6e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
KPPHDEDB_00335 1.7e-243 S Calcineurin-like phosphoesterase
KPPHDEDB_00336 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KPPHDEDB_00337 3.3e-225 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
KPPHDEDB_00338 5e-114
KPPHDEDB_00339 0.0 4.2.1.53 S MCRA family
KPPHDEDB_00340 1.4e-75 yneG S Domain of unknown function (DUF4186)
KPPHDEDB_00341 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
KPPHDEDB_00342 7.1e-129 S Virulence factor BrkB
KPPHDEDB_00343 6.2e-19 L Integrase core domain
KPPHDEDB_00344 2e-103
KPPHDEDB_00345 4.3e-54 V ATPases associated with a variety of cellular activities
KPPHDEDB_00346 2.9e-179 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KPPHDEDB_00347 4.1e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPPHDEDB_00348 4.1e-38 tccB2 V DivIVA protein
KPPHDEDB_00349 6.1e-43 yggT S YGGT family
KPPHDEDB_00350 4.9e-79 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KPPHDEDB_00351 1.2e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPPHDEDB_00352 1.4e-239 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPPHDEDB_00353 5.7e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KPPHDEDB_00354 1.6e-163 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KPPHDEDB_00355 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KPPHDEDB_00356 7.1e-228 O AAA domain (Cdc48 subfamily)
KPPHDEDB_00357 3e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KPPHDEDB_00358 3.6e-61 S Thiamine-binding protein
KPPHDEDB_00359 3.9e-241 O SERine Proteinase INhibitors
KPPHDEDB_00360 2.7e-191 K helix_turn _helix lactose operon repressor
KPPHDEDB_00361 6.2e-241 lacY P LacY proton/sugar symporter
KPPHDEDB_00362 1.5e-302 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KPPHDEDB_00363 2.2e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00364 1.1e-203 P NMT1/THI5 like
KPPHDEDB_00365 7.6e-214 iunH1 3.2.2.1 F nucleoside hydrolase
KPPHDEDB_00366 5.8e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPPHDEDB_00367 6.5e-112 recO L Involved in DNA repair and RecF pathway recombination
KPPHDEDB_00368 7.6e-284 I acetylesterase activity
KPPHDEDB_00369 8.2e-232 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KPPHDEDB_00370 2.9e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KPPHDEDB_00371 2.1e-233 2.7.11.1 NU Tfp pilus assembly protein FimV
KPPHDEDB_00373 2e-44 S Protein of unknown function (DUF3052)
KPPHDEDB_00374 1.5e-158 lon T Belongs to the peptidase S16 family
KPPHDEDB_00375 0.0 S Zincin-like metallopeptidase
KPPHDEDB_00376 3.7e-285 uvrD2 3.6.4.12 L DNA helicase
KPPHDEDB_00377 3.2e-287 mphA S Aminoglycoside phosphotransferase
KPPHDEDB_00378 1.2e-32 S Protein of unknown function (DUF3107)
KPPHDEDB_00379 5.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
KPPHDEDB_00380 7.6e-124 S Vitamin K epoxide reductase
KPPHDEDB_00381 2e-166 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KPPHDEDB_00382 1.1e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KPPHDEDB_00383 6e-157 S Patatin-like phospholipase
KPPHDEDB_00384 1.7e-15 S Amidohydrolase
KPPHDEDB_00385 1.2e-10 6.3.1.2 E glutamine synthetase
KPPHDEDB_00387 1.2e-64 V ABC transporter
KPPHDEDB_00388 9.7e-77 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_00389 1e-203 S Domain of unknown function (DUF4143)
KPPHDEDB_00390 4.6e-110 XK27_08050 O prohibitin homologues
KPPHDEDB_00391 4.3e-110 E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00392 5.2e-142 tcyA ET Bacterial periplasmic substrate-binding proteins
KPPHDEDB_00393 1.9e-138 3.6.3.21 E ATPases associated with a variety of cellular activities
KPPHDEDB_00394 1.2e-241 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
KPPHDEDB_00395 2.2e-229 S Peptidase dimerisation domain
KPPHDEDB_00396 0.0 E ATPases associated with a variety of cellular activities
KPPHDEDB_00397 0.0 E Branched-chain amino acid transport system / permease component
KPPHDEDB_00398 2.9e-218 E Receptor family ligand binding region
KPPHDEDB_00399 8.4e-201 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KPPHDEDB_00400 5e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPPHDEDB_00401 3.1e-155 E Glyoxalase-like domain
KPPHDEDB_00402 2.5e-42 XAC3035 O Glutaredoxin
KPPHDEDB_00403 1.1e-223 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KPPHDEDB_00404 7.6e-126 cjaA ET Bacterial periplasmic substrate-binding proteins
KPPHDEDB_00405 4.1e-115 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
KPPHDEDB_00406 6.8e-111 glnP E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00407 6.4e-98 papP E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00408 6.5e-119 ypfH S Phospholipase/Carboxylesterase
KPPHDEDB_00409 0.0 tetP J Elongation factor G, domain IV
KPPHDEDB_00410 1.2e-131 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
KPPHDEDB_00412 1e-102 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KPPHDEDB_00413 6.3e-168 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KPPHDEDB_00414 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KPPHDEDB_00415 4.6e-239 carA 6.3.5.5 F Belongs to the CarA family
KPPHDEDB_00416 6e-76 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPPHDEDB_00417 4e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPPHDEDB_00418 4.1e-112 ybbL V ATPases associated with a variety of cellular activities
KPPHDEDB_00419 3e-126 ybbM V Uncharacterised protein family (UPF0014)
KPPHDEDB_00420 0.0 G Glycosyl hydrolase family 20, domain 2
KPPHDEDB_00421 2.1e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KPPHDEDB_00422 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPPHDEDB_00423 0.0 S Tetratricopeptide repeat
KPPHDEDB_00424 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KPPHDEDB_00425 5.5e-139 bioM P ATPases associated with a variety of cellular activities
KPPHDEDB_00426 5.7e-228 E Aminotransferase class I and II
KPPHDEDB_00427 1e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
KPPHDEDB_00428 1.3e-198 S Glycosyltransferase, group 2 family protein
KPPHDEDB_00429 1.9e-102 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPPHDEDB_00430 0.0 ecfA GP ABC transporter, ATP-binding protein
KPPHDEDB_00431 9.1e-47 yhbY J CRS1_YhbY
KPPHDEDB_00432 5.4e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KPPHDEDB_00433 1.9e-57 J TM2 domain
KPPHDEDB_00434 1.8e-184 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KPPHDEDB_00435 2.2e-247 EGP Major facilitator Superfamily
KPPHDEDB_00436 3e-246 rarA L Recombination factor protein RarA
KPPHDEDB_00437 0.0 L DEAD DEAH box helicase
KPPHDEDB_00438 4.3e-176 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
KPPHDEDB_00439 1.6e-42 T Pfam Adenylate and Guanylate cyclase catalytic domain
KPPHDEDB_00440 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KPPHDEDB_00441 8.3e-282 phoN I PAP2 superfamily
KPPHDEDB_00442 3e-185 gluD E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00443 3.9e-106 gluC E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00444 4.4e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
KPPHDEDB_00445 1e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
KPPHDEDB_00446 1.2e-19 2.7.13.3 T Histidine kinase
KPPHDEDB_00447 3.9e-181 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
KPPHDEDB_00449 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KPPHDEDB_00450 1.9e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
KPPHDEDB_00451 1.2e-210 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
KPPHDEDB_00452 1.2e-303 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KPPHDEDB_00453 0.0 clpC O ATPase family associated with various cellular activities (AAA)
KPPHDEDB_00454 4e-173 uspA T Belongs to the universal stress protein A family
KPPHDEDB_00455 1.3e-162 S Protein of unknown function (DUF3027)
KPPHDEDB_00456 6.5e-66 cspB K 'Cold-shock' DNA-binding domain
KPPHDEDB_00457 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPPHDEDB_00458 4.3e-133 KT Response regulator receiver domain protein
KPPHDEDB_00459 8.6e-66
KPPHDEDB_00460 1.7e-34 S Proteins of 100 residues with WXG
KPPHDEDB_00461 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPPHDEDB_00462 3.9e-37 K 'Cold-shock' DNA-binding domain
KPPHDEDB_00463 2.6e-70 S LytR cell envelope-related transcriptional attenuator
KPPHDEDB_00464 2.1e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPPHDEDB_00465 3.3e-192 moxR S ATPase family associated with various cellular activities (AAA)
KPPHDEDB_00466 5.3e-170 S Protein of unknown function DUF58
KPPHDEDB_00467 1.3e-88
KPPHDEDB_00468 2.5e-184 S von Willebrand factor (vWF) type A domain
KPPHDEDB_00469 1.7e-161 S von Willebrand factor (vWF) type A domain
KPPHDEDB_00470 1.8e-41
KPPHDEDB_00471 1e-46
KPPHDEDB_00472 2.1e-288 S PGAP1-like protein
KPPHDEDB_00474 7.1e-110 ykoE S ABC-type cobalt transport system, permease component
KPPHDEDB_00475 2.5e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
KPPHDEDB_00476 0.0 S Lysylphosphatidylglycerol synthase TM region
KPPHDEDB_00477 6.2e-42 hup L Belongs to the bacterial histone-like protein family
KPPHDEDB_00478 1.8e-24 L HTH-like domain
KPPHDEDB_00480 2.1e-39 relB L RelB antitoxin
KPPHDEDB_00481 1.2e-48 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KPPHDEDB_00482 5.3e-27 G Transporter major facilitator family protein
KPPHDEDB_00483 1.1e-284 mmuP E amino acid
KPPHDEDB_00485 1.1e-64 yeaO K Protein of unknown function, DUF488
KPPHDEDB_00486 3.8e-75
KPPHDEDB_00487 5e-156 3.6.4.12
KPPHDEDB_00488 2.3e-16 yijF S Domain of unknown function (DUF1287)
KPPHDEDB_00489 5.4e-07 V ATPases associated with a variety of cellular activities
KPPHDEDB_00490 2.1e-30 S Virulence protein RhuM family
KPPHDEDB_00492 6.1e-13 IQ short chain dehydrogenase
KPPHDEDB_00493 6.5e-57 yeaO K Protein of unknown function, DUF488
KPPHDEDB_00494 1.4e-119 XK27_08510 KL DEAD-like helicases superfamily
KPPHDEDB_00495 1.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
KPPHDEDB_00496 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPPHDEDB_00497 3.3e-120 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPPHDEDB_00498 4.7e-17 V ABC transporter transmembrane region
KPPHDEDB_00499 8e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
KPPHDEDB_00500 2.1e-205 MA20_36090 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_00501 1.3e-27
KPPHDEDB_00502 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPPHDEDB_00503 1.2e-180 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPPHDEDB_00504 5.8e-158 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KPPHDEDB_00505 1.9e-175 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
KPPHDEDB_00506 1.7e-287 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPPHDEDB_00507 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KPPHDEDB_00508 2.4e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPPHDEDB_00509 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KPPHDEDB_00510 8.2e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KPPHDEDB_00511 4.8e-154 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
KPPHDEDB_00512 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPPHDEDB_00513 3e-96 sixA 3.6.1.55 T Phosphoglycerate mutase family
KPPHDEDB_00514 2.7e-194 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KPPHDEDB_00515 1.9e-94 S Phospholipase/Carboxylesterase
KPPHDEDB_00517 4.9e-131 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPPHDEDB_00518 2.6e-107 S phosphoesterase or phosphohydrolase
KPPHDEDB_00519 2.5e-23 ydhF S Aldo/keto reductase family
KPPHDEDB_00520 7.6e-12 ydhF S Aldo/keto reductase family
KPPHDEDB_00521 1.1e-167 I alpha/beta hydrolase fold
KPPHDEDB_00523 2.5e-129
KPPHDEDB_00524 6.6e-124 S Plasmid pRiA4b ORF-3-like protein
KPPHDEDB_00525 1.8e-37 rarD S EamA-like transporter family
KPPHDEDB_00527 2.2e-30 S zinc finger
KPPHDEDB_00528 1.6e-206 L Uncharacterized conserved protein (DUF2075)
KPPHDEDB_00529 3.1e-31 mazG S MazG-like family
KPPHDEDB_00530 1.2e-12 2.5.1.19 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KPPHDEDB_00531 2.5e-62 CP_1020 S zinc finger
KPPHDEDB_00532 2.1e-138
KPPHDEDB_00533 1.1e-90 bcp 1.11.1.15 O Redoxin
KPPHDEDB_00535 2.4e-158 S Sucrose-6F-phosphate phosphohydrolase
KPPHDEDB_00536 6e-157 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
KPPHDEDB_00537 1.2e-241 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
KPPHDEDB_00538 1e-81
KPPHDEDB_00539 0.0 S Glycosyl hydrolases related to GH101 family, GH129
KPPHDEDB_00540 2.2e-66 E ABC transporter, substrate-binding protein, family 5
KPPHDEDB_00541 1.9e-302 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KPPHDEDB_00542 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
KPPHDEDB_00543 2e-178 K helix_turn _helix lactose operon repressor
KPPHDEDB_00546 1.5e-134 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KPPHDEDB_00547 5.4e-180 hemN H Involved in the biosynthesis of porphyrin-containing compound
KPPHDEDB_00548 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPPHDEDB_00549 3e-193 G Bacterial extracellular solute-binding protein
KPPHDEDB_00550 1.6e-123 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
KPPHDEDB_00551 3.5e-137 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
KPPHDEDB_00552 6.9e-247 G Bacterial extracellular solute-binding protein
KPPHDEDB_00553 1.8e-226 G Bacterial extracellular solute-binding protein
KPPHDEDB_00554 1.8e-223 G Bacterial extracellular solute-binding protein
KPPHDEDB_00555 9e-204 G Glycosyl hydrolase family 20, domain 2
KPPHDEDB_00556 1.5e-31 3.1.3.18 S phosphoglycolate phosphatase activity
KPPHDEDB_00557 4.6e-140 G Extracellular solute-binding protein
KPPHDEDB_00558 7.3e-117 YSH1 S Metallo-beta-lactamase superfamily
KPPHDEDB_00559 5e-100 gtsC P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00560 1.2e-102 gtsB G PFAM Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00561 7.7e-128 malK P Belongs to the ABC transporter superfamily
KPPHDEDB_00562 7.6e-94 M1-431 S Protein of unknown function (DUF1706)
KPPHDEDB_00563 1.7e-166 L Helix-turn-helix domain
KPPHDEDB_00564 3.4e-41 L Resolvase, N terminal domain
KPPHDEDB_00565 2.5e-210 phoN I PAP2 superfamily
KPPHDEDB_00566 3.3e-115 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPPHDEDB_00567 9.2e-78 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPPHDEDB_00568 1.7e-92 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KPPHDEDB_00569 1.3e-201 G Bacterial extracellular solute-binding protein
KPPHDEDB_00570 3.6e-128 ugpE G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00571 4.5e-132 ugpA P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00572 1.6e-159 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KPPHDEDB_00573 2.1e-156 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPPHDEDB_00574 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KPPHDEDB_00575 1.3e-73 2.3.1.57 K Acetyltransferase (GNAT) domain
KPPHDEDB_00576 1.3e-156 fahA Q Fumarylacetoacetate (FAA) hydrolase family
KPPHDEDB_00579 1.9e-125 L HTH-like domain
KPPHDEDB_00580 9.2e-228 xerC_1 L Belongs to the 'phage' integrase family
KPPHDEDB_00581 7.8e-193 L Phage integrase family
KPPHDEDB_00582 2.2e-201 L Phage integrase, N-terminal SAM-like domain
KPPHDEDB_00583 7.5e-33 L PFAM Integrase catalytic
KPPHDEDB_00584 7.3e-121 F Permease family
KPPHDEDB_00585 7.8e-39 F Permease family
KPPHDEDB_00586 5.6e-52 rbsK 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPPHDEDB_00587 1.4e-84 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00588 9.3e-103 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00589 1e-118 G Bacterial extracellular solute-binding protein
KPPHDEDB_00590 3.9e-77 F Inosine-uridine preferring nucleoside hydrolase
KPPHDEDB_00591 4.1e-86 K Periplasmic binding protein domain
KPPHDEDB_00592 6.3e-19 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00593 2.7e-41 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00594 1.2e-28 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00595 4.7e-113 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00596 5.1e-223 glf 5.4.99.9 M UDP-galactopyranose mutase
KPPHDEDB_00597 4.1e-81 S AAA domain
KPPHDEDB_00598 9e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPPHDEDB_00599 2.5e-283 S Psort location Cytoplasmic, score
KPPHDEDB_00600 9e-144
KPPHDEDB_00601 5.6e-130 L Transposase
KPPHDEDB_00602 4.7e-102 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00603 2.3e-16 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_00604 2.4e-228 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
KPPHDEDB_00605 4.9e-165 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
KPPHDEDB_00606 4.2e-211 2.4.1.288 GT2 S Glycosyltransferase like family 2
KPPHDEDB_00607 1.6e-180 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
KPPHDEDB_00608 1.6e-130 rgpC U Transport permease protein
KPPHDEDB_00609 1.6e-113 S Polysaccharide pyruvyl transferase
KPPHDEDB_00610 2.8e-46 S EamA-like transporter family
KPPHDEDB_00611 1.4e-102
KPPHDEDB_00612 2.2e-123
KPPHDEDB_00613 2e-120 V ATPases associated with a variety of cellular activities
KPPHDEDB_00614 1.5e-56 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_00615 5.9e-43
KPPHDEDB_00616 4.9e-72 yycO S PFAM Orthopoxvirus protein of
KPPHDEDB_00617 1.4e-29
KPPHDEDB_00618 2e-93 S Domain of unknown function (DUF4192)
KPPHDEDB_00619 2.4e-60 K helix_turn_helix, Lux Regulon
KPPHDEDB_00620 1.7e-56 2.7.13.3 T Histidine kinase
KPPHDEDB_00621 3.9e-165 L Phage integrase family
KPPHDEDB_00622 1.5e-87 6.3.5.5 HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)
KPPHDEDB_00623 5.4e-15 F ATP-grasp domain
KPPHDEDB_00624 8.1e-78 G MFS/sugar transport protein
KPPHDEDB_00625 7.8e-156 F ATP-grasp domain
KPPHDEDB_00628 3.6e-70 L Phage integrase family
KPPHDEDB_00630 3.1e-122 V ABC transporter
KPPHDEDB_00633 3e-17 U Type IV secretory system Conjugative DNA transfer
KPPHDEDB_00634 2e-231 T Histidine kinase
KPPHDEDB_00635 1.1e-122 K helix_turn_helix, Lux Regulon
KPPHDEDB_00636 9.6e-121 V ABC transporter
KPPHDEDB_00637 1.4e-17
KPPHDEDB_00638 2.9e-293 E Asparagine synthase
KPPHDEDB_00639 3.2e-35 E Asparagine synthase
KPPHDEDB_00640 3.6e-260 3.4.21.83 E Prolyl oligopeptidase family
KPPHDEDB_00641 7.7e-138 V ABC transporter
KPPHDEDB_00642 1.8e-222 V Efflux ABC transporter, permease protein
KPPHDEDB_00643 3e-66
KPPHDEDB_00644 5.2e-41
KPPHDEDB_00645 2.5e-196 T Histidine kinase
KPPHDEDB_00646 4.9e-117 K Bacterial regulatory proteins, luxR family
KPPHDEDB_00647 1.2e-116 V VanZ like family
KPPHDEDB_00648 5.3e-96 rpoE4 K Sigma-70 region 2
KPPHDEDB_00649 1.1e-22 S Psort location CytoplasmicMembrane, score
KPPHDEDB_00650 2.1e-106
KPPHDEDB_00651 1.7e-137
KPPHDEDB_00652 1.1e-169 yfiL V ATPases associated with a variety of cellular activities
KPPHDEDB_00653 1.1e-65
KPPHDEDB_00654 5.2e-29 V ABC transporter transmembrane region
KPPHDEDB_00655 3.3e-79 V ABC transporter
KPPHDEDB_00656 2.1e-77 V FtsX-like permease family
KPPHDEDB_00657 2.5e-51 T Histidine kinase
KPPHDEDB_00658 1.9e-74 K Bacterial regulatory proteins, luxR family
KPPHDEDB_00659 4.4e-97 KLT Protein kinase domain
KPPHDEDB_00661 7.3e-35 ptrB 3.4.21.83 E Protease II
KPPHDEDB_00662 9.8e-77 G Glycosyl hydrolase family 20, domain 2
KPPHDEDB_00663 4.1e-242 L Phage integrase family
KPPHDEDB_00665 3.6e-20 S Protein of unknown function (DUF2599)
KPPHDEDB_00666 1e-128
KPPHDEDB_00667 1.6e-80
KPPHDEDB_00668 7.3e-236 L Phage integrase family
KPPHDEDB_00669 3.9e-09
KPPHDEDB_00670 4.6e-189 3.6.4.12 K Divergent AAA domain protein
KPPHDEDB_00672 2.4e-27 K Psort location Cytoplasmic, score
KPPHDEDB_00674 3.9e-278 V FtsX-like permease family
KPPHDEDB_00675 1.2e-110 V ABC transporter
KPPHDEDB_00676 1.3e-116 T PhoQ Sensor
KPPHDEDB_00677 4.9e-109 K COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPPHDEDB_00678 4.9e-22 K trisaccharide binding
KPPHDEDB_00679 5.1e-16 EGP Major Facilitator Superfamily
KPPHDEDB_00681 3.5e-120 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KPPHDEDB_00682 3.5e-129 V ATPases associated with a variety of cellular activities
KPPHDEDB_00683 3.8e-170 V MacB-like periplasmic core domain
KPPHDEDB_00684 1e-87
KPPHDEDB_00685 6.1e-214 L Transposase
KPPHDEDB_00687 2.1e-117 S EamA-like transporter family
KPPHDEDB_00688 2.2e-121 L IstB-like ATP binding protein
KPPHDEDB_00689 2.2e-87 L PFAM Integrase catalytic
KPPHDEDB_00690 3.1e-33 L PFAM Integrase catalytic
KPPHDEDB_00691 2.5e-93 L Integrase core domain
KPPHDEDB_00692 3.5e-40 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_00693 3.5e-52 FG bis(5'-adenosyl)-triphosphatase activity
KPPHDEDB_00694 4e-177 uxaC 5.3.1.12 G Glucuronate isomerase
KPPHDEDB_00695 2e-194 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
KPPHDEDB_00696 2e-233 rspA 4.2.1.8 M mandelate racemase muconate lactonizing
KPPHDEDB_00697 1.1e-230 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPPHDEDB_00698 2.4e-67 K Periplasmic binding proteins and sugar binding domain of LacI family
KPPHDEDB_00699 6.7e-62 K Periplasmic binding proteins and sugar binding domain of LacI family
KPPHDEDB_00700 6.8e-48 G MFS/sugar transport protein
KPPHDEDB_00701 1.6e-15 G MFS/sugar transport protein
KPPHDEDB_00702 2.8e-19 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPPHDEDB_00703 2e-171 uxuT G MFS/sugar transport protein
KPPHDEDB_00704 9.1e-12 L Helix-turn-helix domain
KPPHDEDB_00705 3.8e-33 L PFAM Integrase catalytic
KPPHDEDB_00706 2.6e-46 L Transposase, Mutator family
KPPHDEDB_00707 3.4e-157 I type I phosphodiesterase nucleotide pyrophosphatase
KPPHDEDB_00708 7.9e-197 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPPHDEDB_00709 1.8e-154 U Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00710 7.9e-147 U Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00711 3.9e-196 P Bacterial extracellular solute-binding protein
KPPHDEDB_00712 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPPHDEDB_00713 1.1e-241 malY 4.4.1.8 E Aminotransferase, class I II
KPPHDEDB_00714 6.6e-160 nanL 4.3.3.7 EM Dihydrodipicolinate synthetase family
KPPHDEDB_00715 1.3e-143 oppF E ATPases associated with a variety of cellular activities
KPPHDEDB_00716 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
KPPHDEDB_00717 7.2e-167 oppB6 EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00718 5.7e-270 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPPHDEDB_00719 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
KPPHDEDB_00720 3.5e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KPPHDEDB_00721 4.5e-121 2.7.1.2 GK ROK family
KPPHDEDB_00722 1.4e-143 L Domain of unknown function (DUF4862)
KPPHDEDB_00723 4.5e-108 K FCD
KPPHDEDB_00724 4.9e-174 lacR K Transcriptional regulator, LacI family
KPPHDEDB_00725 1.9e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPPHDEDB_00726 3.2e-68 rbsD 5.4.99.62 G RbsD / FucU transport protein family
KPPHDEDB_00727 1.5e-161 rbsB G Periplasmic binding protein domain
KPPHDEDB_00728 2.2e-166 rbsC U Branched-chain amino acid transport system / permease component
KPPHDEDB_00729 1.6e-277 rbsA 3.6.3.17 G ATPases associated with a variety of cellular activities
KPPHDEDB_00730 5.7e-186 rbsR K helix_turn _helix lactose operon repressor
KPPHDEDB_00731 1.1e-259 V ABC transporter transmembrane region
KPPHDEDB_00732 5.7e-10 S Bifunctional DNA primase/polymerase, N-terminal
KPPHDEDB_00734 8.5e-10 M domain protein
KPPHDEDB_00735 7.2e-242 U Spy0128-like isopeptide containing domain
KPPHDEDB_00736 1.5e-53 D nuclear chromosome segregation
KPPHDEDB_00737 1.7e-175 D ftsk spoiiie
KPPHDEDB_00739 8e-16
KPPHDEDB_00740 1.9e-75 addB 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KPPHDEDB_00743 4.1e-275 S ATPase domain predominantly from Archaea
KPPHDEDB_00744 4.6e-269 aroP E aromatic amino acid transport protein AroP K03293
KPPHDEDB_00745 9.2e-101 K Transcriptional regulator C-terminal region
KPPHDEDB_00746 6.3e-128 V ABC transporter
KPPHDEDB_00747 0.0 V FtsX-like permease family
KPPHDEDB_00748 3.7e-266 cycA E Amino acid permease
KPPHDEDB_00749 1.1e-76 ydgJ K helix_turn_helix multiple antibiotic resistance protein
KPPHDEDB_00750 0.0 lmrA1 V ABC transporter, ATP-binding protein
KPPHDEDB_00751 0.0 lmrA2 V ABC transporter transmembrane region
KPPHDEDB_00752 1e-151 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPPHDEDB_00754 7.8e-183 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPPHDEDB_00755 2.7e-29
KPPHDEDB_00756 4.7e-114
KPPHDEDB_00757 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPPHDEDB_00758 2e-46
KPPHDEDB_00759 6.5e-204 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KPPHDEDB_00760 2.4e-262 pepC 3.4.22.40 E Peptidase C1-like family
KPPHDEDB_00761 2.6e-175 appB EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00762 9.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
KPPHDEDB_00763 0.0 oppD P Belongs to the ABC transporter superfamily
KPPHDEDB_00764 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KPPHDEDB_00766 6e-250 EGP Major Facilitator Superfamily
KPPHDEDB_00767 6.8e-267 S AAA domain
KPPHDEDB_00768 1.5e-58 G domain, Protein
KPPHDEDB_00769 1.2e-249 S Domain of unknown function (DUF4143)
KPPHDEDB_00770 1.8e-270 S ATPase domain predominantly from Archaea
KPPHDEDB_00771 0.0 mdlA2 V ABC transporter
KPPHDEDB_00772 0.0 yknV V ABC transporter
KPPHDEDB_00773 2.9e-196 S Fic/DOC family
KPPHDEDB_00774 1.3e-17 L HTH-like domain
KPPHDEDB_00775 1.6e-107 XK27_00240 K Fic/DOC family
KPPHDEDB_00776 5.5e-28 K helix_turn_helix, arabinose operon control protein
KPPHDEDB_00777 5.2e-90 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KPPHDEDB_00778 2.3e-62 2.7.1.2 GK ROK family
KPPHDEDB_00779 1.4e-113 xylE U Sugar (and other) transporter
KPPHDEDB_00780 1.4e-153 lipA I Hydrolase, alpha beta domain protein
KPPHDEDB_00782 2e-185 tatD L TatD related DNase
KPPHDEDB_00783 0.0 kup P Transport of potassium into the cell
KPPHDEDB_00784 1.3e-159 S Glutamine amidotransferase domain
KPPHDEDB_00785 2e-134 T HD domain
KPPHDEDB_00787 4.5e-184 V ABC transporter
KPPHDEDB_00788 1.4e-217 V ABC transporter permease
KPPHDEDB_00789 0.0 pflA S Protein of unknown function (DUF4012)
KPPHDEDB_00790 1.1e-199 I transferase activity, transferring acyl groups other than amino-acyl groups
KPPHDEDB_00791 6.7e-52 S Predicted membrane protein (DUF2142)
KPPHDEDB_00792 8.1e-55 S Protein of unknown function (DUF3800)
KPPHDEDB_00794 4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KPPHDEDB_00795 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
KPPHDEDB_00796 1.1e-41 csoR S Metal-sensitive transcriptional repressor
KPPHDEDB_00797 4.2e-187 rmuC S RmuC family
KPPHDEDB_00798 4.7e-98 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPPHDEDB_00799 3.5e-157 spoU 2.1.1.185 J RNA methyltransferase TrmH family
KPPHDEDB_00800 3.5e-185 K Psort location Cytoplasmic, score
KPPHDEDB_00801 2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPPHDEDB_00802 2.1e-285 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPPHDEDB_00803 7.9e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPPHDEDB_00804 5.2e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
KPPHDEDB_00805 3.3e-52 S Protein of unknown function (DUF2469)
KPPHDEDB_00806 2.8e-279 S Histidine phosphatase superfamily (branch 2)
KPPHDEDB_00807 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
KPPHDEDB_00808 4.2e-252 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KPPHDEDB_00810 2e-62 tyrA 5.4.99.5 E Chorismate mutase type II
KPPHDEDB_00811 8.7e-295 S domain protein
KPPHDEDB_00812 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPPHDEDB_00813 1.8e-281 E Bacterial extracellular solute-binding proteins, family 5 Middle
KPPHDEDB_00814 5.6e-129 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPPHDEDB_00815 2.4e-131 KT Transcriptional regulatory protein, C terminal
KPPHDEDB_00816 1.2e-78
KPPHDEDB_00817 1.6e-97 mntP P Probably functions as a manganese efflux pump
KPPHDEDB_00818 2.8e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KPPHDEDB_00819 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KPPHDEDB_00820 0.0 K RNA polymerase II activating transcription factor binding
KPPHDEDB_00821 8e-75 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_00823 1e-35 G Hypothetical glycosyl hydrolase 6
KPPHDEDB_00826 8.9e-12
KPPHDEDB_00827 7.9e-21 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
KPPHDEDB_00828 1.4e-203 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPPHDEDB_00829 1.1e-144 atpB C it plays a direct role in the translocation of protons across the membrane
KPPHDEDB_00830 1.5e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPPHDEDB_00831 2.7e-59 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPPHDEDB_00832 5.2e-145 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPPHDEDB_00833 7.4e-305 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPPHDEDB_00834 1.6e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPPHDEDB_00835 1.5e-280 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPPHDEDB_00836 1.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KPPHDEDB_00837 5e-134 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KPPHDEDB_00838 1.2e-156 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
KPPHDEDB_00839 3e-185
KPPHDEDB_00840 4.2e-181
KPPHDEDB_00841 4.8e-166 trxA2 O Tetratricopeptide repeat
KPPHDEDB_00842 2.4e-118 cyaA 4.6.1.1 S CYTH
KPPHDEDB_00844 1e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
KPPHDEDB_00845 2.8e-182 plsC2 2.3.1.51 I Phosphate acyltransferases
KPPHDEDB_00846 3.2e-181 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KPPHDEDB_00847 2.2e-226 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPPHDEDB_00848 5.6e-214 P Bacterial extracellular solute-binding protein
KPPHDEDB_00849 6.9e-162 U Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00850 5.3e-127 U Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00851 3.5e-225 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPPHDEDB_00852 5.4e-176 S CAAX protease self-immunity
KPPHDEDB_00853 1.2e-127 M Mechanosensitive ion channel
KPPHDEDB_00854 8.1e-271 aspA 4.3.1.1 E Fumarase C C-terminus
KPPHDEDB_00855 3.3e-135 K Bacterial regulatory proteins, tetR family
KPPHDEDB_00856 3.3e-237 MA20_36090 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_00857 5.5e-86 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPPHDEDB_00858 5.8e-11 XK27_04590 S NADPH-dependent FMN reductase
KPPHDEDB_00863 8.2e-23 yxiO G Major facilitator Superfamily
KPPHDEDB_00864 2.1e-22
KPPHDEDB_00865 9.8e-189 K Helix-turn-helix XRE-family like proteins
KPPHDEDB_00866 1.1e-21 yxiO G Major facilitator Superfamily
KPPHDEDB_00867 8.1e-54 relB L RelB antitoxin
KPPHDEDB_00868 6e-20 T Toxic component of a toxin-antitoxin (TA) module
KPPHDEDB_00869 2.2e-131 K helix_turn_helix, mercury resistance
KPPHDEDB_00870 1.7e-232 yxiO S Vacuole effluxer Atg22 like
KPPHDEDB_00871 2.7e-196 yegV G pfkB family carbohydrate kinase
KPPHDEDB_00872 5.5e-29 rpmB J Ribosomal L28 family
KPPHDEDB_00873 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
KPPHDEDB_00874 7.3e-38 O Bacterial Ig-like domain (group 3)
KPPHDEDB_00875 1.2e-175 U Sodium:dicarboxylate symporter family
KPPHDEDB_00876 2.5e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
KPPHDEDB_00877 1.2e-154 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KPPHDEDB_00878 5.9e-310 yegQ O Peptidase family U32 C-terminal domain
KPPHDEDB_00879 2.8e-182 yfiH Q Multi-copper polyphenol oxidoreductase laccase
KPPHDEDB_00880 4.3e-158 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KPPHDEDB_00881 3.5e-123 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPPHDEDB_00882 2.9e-56 D nuclear chromosome segregation
KPPHDEDB_00883 2.1e-260 pepC 3.4.22.40 E Peptidase C1-like family
KPPHDEDB_00884 3.6e-213 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPPHDEDB_00885 6.1e-235 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPPHDEDB_00886 7.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPPHDEDB_00887 1.1e-229 EGP Sugar (and other) transporter
KPPHDEDB_00888 1.3e-204 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KPPHDEDB_00889 1.8e-139 KT Transcriptional regulatory protein, C terminal
KPPHDEDB_00890 2.3e-180 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
KPPHDEDB_00891 3.5e-153 pstC P probably responsible for the translocation of the substrate across the membrane
KPPHDEDB_00892 1.1e-168 pstA P Phosphate transport system permease
KPPHDEDB_00893 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPPHDEDB_00894 6.7e-91 lemA S LemA family
KPPHDEDB_00895 0.0 S Predicted membrane protein (DUF2207)
KPPHDEDB_00896 1.7e-12 S Predicted membrane protein (DUF2207)
KPPHDEDB_00897 7.5e-173 S Predicted membrane protein (DUF2207)
KPPHDEDB_00898 2.9e-18
KPPHDEDB_00899 4.8e-170 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
KPPHDEDB_00900 2.5e-197 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KPPHDEDB_00901 2.8e-45 K Helix-turn-helix XRE-family like proteins
KPPHDEDB_00902 4.7e-111 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPPHDEDB_00903 6.1e-35 CP_0960 S Belongs to the UPF0109 family
KPPHDEDB_00904 1.1e-59 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KPPHDEDB_00905 4.8e-140 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
KPPHDEDB_00906 4.8e-268 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
KPPHDEDB_00907 1.2e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPPHDEDB_00908 2e-112 ribE 2.5.1.9 H Lumazine binding domain
KPPHDEDB_00909 3e-234 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPPHDEDB_00910 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KPPHDEDB_00911 2.7e-165 S Endonuclease/Exonuclease/phosphatase family
KPPHDEDB_00912 2.9e-262 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPPHDEDB_00913 6.2e-160 P Cation efflux family
KPPHDEDB_00914 1.1e-300 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPPHDEDB_00915 1.1e-137 guaA1 6.3.5.2 F Peptidase C26
KPPHDEDB_00916 0.0 yjjK S ABC transporter
KPPHDEDB_00917 7.3e-63 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
KPPHDEDB_00918 2.6e-39 stbC S Plasmid stability protein
KPPHDEDB_00919 1.7e-91 ilvN 2.2.1.6 E ACT domain
KPPHDEDB_00920 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
KPPHDEDB_00921 2.9e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPPHDEDB_00922 7.6e-31 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KPPHDEDB_00923 1.4e-118 yceD S Uncharacterized ACR, COG1399
KPPHDEDB_00924 3.1e-119
KPPHDEDB_00925 2.1e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPPHDEDB_00926 2e-51 S Protein of unknown function (DUF3039)
KPPHDEDB_00927 6.4e-190 yghZ C Aldo/keto reductase family
KPPHDEDB_00928 1.6e-68 soxR K MerR, DNA binding
KPPHDEDB_00929 7.2e-115
KPPHDEDB_00930 2e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPPHDEDB_00931 2.6e-160
KPPHDEDB_00932 4.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KPPHDEDB_00933 1e-131 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPPHDEDB_00935 8e-214 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
KPPHDEDB_00936 2.1e-241 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
KPPHDEDB_00937 9.8e-228 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
KPPHDEDB_00938 6.2e-169 S Auxin Efflux Carrier
KPPHDEDB_00941 0.0 pgi 5.3.1.9 G Belongs to the GPI family
KPPHDEDB_00942 3e-254 abcT3 P ATPases associated with a variety of cellular activities
KPPHDEDB_00943 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00944 1.1e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPPHDEDB_00945 5.1e-140 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KPPHDEDB_00946 1.2e-149 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPPHDEDB_00947 1.4e-209 K helix_turn _helix lactose operon repressor
KPPHDEDB_00948 5e-296 P Belongs to the ABC transporter superfamily
KPPHDEDB_00949 5.4e-173 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KPPHDEDB_00950 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
KPPHDEDB_00951 5.8e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
KPPHDEDB_00952 4.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPPHDEDB_00953 3.5e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
KPPHDEDB_00954 2.1e-163 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPPHDEDB_00955 3.1e-130 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPPHDEDB_00956 1.9e-56 M Lysin motif
KPPHDEDB_00957 2.6e-49 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPPHDEDB_00958 1.9e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KPPHDEDB_00959 0.0 L DNA helicase
KPPHDEDB_00960 1.9e-92 mraZ K Belongs to the MraZ family
KPPHDEDB_00961 4.4e-197 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPPHDEDB_00962 3.7e-73 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KPPHDEDB_00963 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
KPPHDEDB_00964 1.6e-152 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPPHDEDB_00965 6.3e-247 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPPHDEDB_00966 8e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPPHDEDB_00967 8.1e-271 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPPHDEDB_00968 6.3e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
KPPHDEDB_00969 2.6e-219 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPPHDEDB_00970 1.8e-284 murC 6.3.2.8 M Belongs to the MurCDEF family
KPPHDEDB_00971 7.3e-184 ftsQ 6.3.2.4 D Cell division protein FtsQ
KPPHDEDB_00972 4.1e-15
KPPHDEDB_00973 5.8e-88 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPPHDEDB_00974 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KPPHDEDB_00975 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KPPHDEDB_00976 1e-248 srrA1 G Bacterial extracellular solute-binding protein
KPPHDEDB_00977 2.7e-169 G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00978 3e-156 lacG G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00979 1.1e-258 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KPPHDEDB_00980 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
KPPHDEDB_00981 4.6e-177 endOF2 3.2.1.14, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
KPPHDEDB_00982 1.3e-85 G Glycosyl hydrolase family 85
KPPHDEDB_00983 3.1e-134 G Glycosyl hydrolase family 85
KPPHDEDB_00984 1.9e-72 G Glycosyl hydrolase family 85
KPPHDEDB_00985 8.6e-204 K helix_turn _helix lactose operon repressor
KPPHDEDB_00986 9.8e-249 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KPPHDEDB_00987 1.5e-260 S Metal-independent alpha-mannosidase (GH125)
KPPHDEDB_00988 4.4e-166 2.7.1.4 G pfkB family carbohydrate kinase
KPPHDEDB_00989 8.5e-221 GK ROK family
KPPHDEDB_00990 2.1e-155 2.7.1.2 GK ROK family
KPPHDEDB_00991 1.6e-202 GK ROK family
KPPHDEDB_00992 1.7e-148 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPPHDEDB_00993 6.1e-239 nagA 3.5.1.25 G Amidohydrolase family
KPPHDEDB_00994 3.1e-303 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
KPPHDEDB_00995 3.8e-188 dppB EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00996 5e-194 dppC EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_00997 0.0 P Belongs to the ABC transporter superfamily
KPPHDEDB_00998 1.6e-96 3.6.1.55 F NUDIX domain
KPPHDEDB_00999 2.2e-309 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
KPPHDEDB_01000 8.8e-160 K Psort location Cytoplasmic, score
KPPHDEDB_01001 4.5e-286 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KPPHDEDB_01002 0.0 smc D Required for chromosome condensation and partitioning
KPPHDEDB_01003 4.9e-190 V Acetyltransferase (GNAT) domain
KPPHDEDB_01004 3.5e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPPHDEDB_01005 1.4e-133 sigH K Belongs to the sigma-70 factor family. ECF subfamily
KPPHDEDB_01006 1.6e-54
KPPHDEDB_01007 6.9e-186 galM 5.1.3.3 G Aldose 1-epimerase
KPPHDEDB_01008 1.4e-189 galM 5.1.3.3 G Aldose 1-epimerase
KPPHDEDB_01009 7.2e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KPPHDEDB_01010 1.5e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPPHDEDB_01011 1.3e-196 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPPHDEDB_01012 2.1e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
KPPHDEDB_01013 9.5e-32 S Unextendable partial coding region
KPPHDEDB_01014 4.9e-198 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KPPHDEDB_01015 4.8e-304 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KPPHDEDB_01016 1.9e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
KPPHDEDB_01017 8.4e-216 iscS1 2.8.1.7 E Aminotransferase class-V
KPPHDEDB_01018 0.0 typA T Elongation factor G C-terminus
KPPHDEDB_01019 2.2e-12 EGP Major facilitator Superfamily
KPPHDEDB_01020 1.5e-09 3.6.4.12 K Divergent AAA domain protein
KPPHDEDB_01021 2e-26 L PFAM Integrase catalytic
KPPHDEDB_01022 1.7e-73
KPPHDEDB_01023 4.3e-191 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
KPPHDEDB_01024 3.8e-193 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
KPPHDEDB_01025 2e-42
KPPHDEDB_01026 2.7e-178 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KPPHDEDB_01027 2e-310 E ABC transporter, substrate-binding protein, family 5
KPPHDEDB_01028 2.2e-152 dppB EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01029 8.7e-171 dppC EP N-terminal TM domain of oligopeptide transport permease C
KPPHDEDB_01030 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
KPPHDEDB_01031 9.7e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
KPPHDEDB_01032 1.9e-147 S Protein of unknown function (DUF3710)
KPPHDEDB_01033 3.2e-120 S Protein of unknown function (DUF3159)
KPPHDEDB_01034 3.5e-241 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPPHDEDB_01035 3.4e-105
KPPHDEDB_01036 0.0 ctpE P E1-E2 ATPase
KPPHDEDB_01037 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPPHDEDB_01038 8e-58 relB L RelB antitoxin
KPPHDEDB_01039 2.5e-86 S PIN domain
KPPHDEDB_01040 0.0 S Protein of unknown function DUF262
KPPHDEDB_01041 2.5e-118 E Psort location Cytoplasmic, score 8.87
KPPHDEDB_01042 8.4e-125 ybhL S Belongs to the BI1 family
KPPHDEDB_01043 3.4e-178 ydeD EG EamA-like transporter family
KPPHDEDB_01044 1.3e-135 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
KPPHDEDB_01045 9.9e-174 L Transposase, Mutator family
KPPHDEDB_01049 7.3e-13 1.3.99.36, 4.1.1.36, 6.3.2.5 H Flavoprotein
KPPHDEDB_01051 1.4e-11 repC K PFAM O-methyltransferase
KPPHDEDB_01052 3.4e-68 ydiF S ATPases associated with a variety of cellular activities
KPPHDEDB_01053 1.5e-201 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_01055 1.6e-33 2.1.1.72 S Adenine-specific methyltransferase EcoRI
KPPHDEDB_01056 2.1e-85 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_01059 1.1e-57 S Fic/DOC family
KPPHDEDB_01060 2.1e-13
KPPHDEDB_01062 2e-112 D ftsk spoiiie
KPPHDEDB_01065 4e-65
KPPHDEDB_01068 1.8e-15 S VRR_NUC
KPPHDEDB_01069 8.4e-70 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPPHDEDB_01070 4.3e-26 rpmI J Ribosomal protein L35
KPPHDEDB_01071 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPPHDEDB_01072 2.3e-170 xerD D recombinase XerD
KPPHDEDB_01073 8.1e-150 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KPPHDEDB_01074 3e-154 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPPHDEDB_01075 4.8e-115 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPPHDEDB_01076 4.7e-154 nrtR 3.6.1.55 F NUDIX hydrolase
KPPHDEDB_01077 5.8e-82 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPPHDEDB_01078 1.8e-51 bioN P Cobalt transport protein
KPPHDEDB_01079 3e-72 cbiO P ATPases associated with a variety of cellular activities
KPPHDEDB_01080 1.1e-58 bioY S BioY family
KPPHDEDB_01081 4.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPPHDEDB_01082 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
KPPHDEDB_01083 1.3e-239 mloB K Putative DNA-binding domain
KPPHDEDB_01084 1.8e-18 L Transposase
KPPHDEDB_01085 1.2e-155 S AAA ATPase domain
KPPHDEDB_01087 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KPPHDEDB_01088 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KPPHDEDB_01089 1e-268 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KPPHDEDB_01091 2.8e-168 hisN 3.1.3.25 G Inositol monophosphatase family
KPPHDEDB_01092 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
KPPHDEDB_01093 7.4e-286 arc O AAA ATPase forming ring-shaped complexes
KPPHDEDB_01094 1.7e-125 apl 3.1.3.1 S SNARE associated Golgi protein
KPPHDEDB_01095 2.7e-126 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KPPHDEDB_01096 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPPHDEDB_01097 3.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPPHDEDB_01098 3.1e-181 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPPHDEDB_01099 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
KPPHDEDB_01100 1.1e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KPPHDEDB_01101 5.5e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPPHDEDB_01102 3.4e-218 vex3 V ABC transporter permease
KPPHDEDB_01103 4e-210 vex1 V Efflux ABC transporter, permease protein
KPPHDEDB_01104 3.2e-110 vex2 V ABC transporter, ATP-binding protein
KPPHDEDB_01105 2.7e-202 K helix_turn _helix lactose operon repressor
KPPHDEDB_01106 8.7e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPPHDEDB_01107 6.8e-118 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPPHDEDB_01108 2.2e-282 clcA P Voltage gated chloride channel
KPPHDEDB_01109 5.8e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPPHDEDB_01110 7.9e-48 S AAA ATPase domain
KPPHDEDB_01111 8.2e-207 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
KPPHDEDB_01112 7.6e-120 mug 3.2.2.28, 6.3.3.2 L Uracil DNA glycosylase superfamily
KPPHDEDB_01113 1.2e-26 L Transposase DDE domain
KPPHDEDB_01114 2.9e-83 Q Isochorismatase family
KPPHDEDB_01115 1.4e-246 U Permease for cytosine/purines, uracil, thiamine, allantoin
KPPHDEDB_01116 2.4e-98 yegV G pfkB family carbohydrate kinase
KPPHDEDB_01117 2.1e-140 yegU O ADP-ribosylglycohydrolase
KPPHDEDB_01118 4.2e-34 K UTRA
KPPHDEDB_01119 1.7e-19 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_01120 2.1e-128 E IrrE N-terminal-like domain
KPPHDEDB_01121 3.1e-204 EGP Major Facilitator Superfamily
KPPHDEDB_01123 6.9e-116 3.2.1.4 GH5,GH9 S acid phosphatase activity
KPPHDEDB_01124 1.2e-158 htpX O Belongs to the peptidase M48B family
KPPHDEDB_01125 4.6e-266 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
KPPHDEDB_01126 3.4e-15
KPPHDEDB_01127 3.7e-206 M LPXTG cell wall anchor motif
KPPHDEDB_01128 6e-100 3.4.22.70 M Sortase family
KPPHDEDB_01129 1.2e-91 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPPHDEDB_01130 2.4e-99 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KPPHDEDB_01131 6.8e-81 ureF J Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPPHDEDB_01132 2.5e-86 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KPPHDEDB_01133 1e-304 ureC 3.5.1.5 E Urease alpha-subunit, N-terminal domain
KPPHDEDB_01134 1.1e-95 ureB 3.5.1.5 E Urease, gamma subunit
KPPHDEDB_01135 3e-110 hoxN S rRNA processing
KPPHDEDB_01136 6.9e-98 urtE E ABC transporter
KPPHDEDB_01137 2.6e-113 urtD S Branched-chain amino acid ATP-binding cassette transporter
KPPHDEDB_01138 4.5e-160 urtC U Branched-chain amino acid transport system / permease component
KPPHDEDB_01139 2.5e-129 urtB U Branched-chain amino acid transport system / permease component
KPPHDEDB_01140 7.7e-196 urtA E Receptor family ligand binding region
KPPHDEDB_01141 0.0 cadA P E1-E2 ATPase
KPPHDEDB_01142 1.8e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
KPPHDEDB_01143 2.5e-258 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KPPHDEDB_01146 1.1e-72 hsp20 O Hsp20/alpha crystallin family
KPPHDEDB_01148 3.4e-15 S Domain of unknown function (DUF4839)
KPPHDEDB_01149 3.8e-127 yplQ S Haemolysin-III related
KPPHDEDB_01150 6.6e-90 yjcF Q Acetyltransferase (GNAT) domain
KPPHDEDB_01151 3.5e-52 ybjQ S Putative heavy-metal-binding
KPPHDEDB_01152 5.8e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KPPHDEDB_01153 1.1e-32 S Domain of unknown function (DUF4928)
KPPHDEDB_01154 5.5e-61 S Domain of unknown function (DUF4928)
KPPHDEDB_01155 3.4e-179 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KPPHDEDB_01156 7.3e-260 L Z1 domain
KPPHDEDB_01157 3e-70 S Putative PD-(D/E)XK family member, (DUF4420)
KPPHDEDB_01158 1.8e-241 S AIPR protein
KPPHDEDB_01159 8e-176 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KPPHDEDB_01160 4.6e-160 M Glycosyltransferase like family 2
KPPHDEDB_01161 3e-110 S Pyridoxamine 5'-phosphate oxidase
KPPHDEDB_01162 1.9e-191 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPPHDEDB_01163 0.0 lysX S Uncharacterised conserved protein (DUF2156)
KPPHDEDB_01164 8.7e-263 S Putative esterase
KPPHDEDB_01165 4.6e-26
KPPHDEDB_01166 2.7e-169 yddG EG EamA-like transporter family
KPPHDEDB_01167 3.1e-92 hsp20 O Hsp20/alpha crystallin family
KPPHDEDB_01168 8.1e-176 telA P Toxic anion resistance protein (TelA)
KPPHDEDB_01169 3.3e-179 P Sulfate ABC transporter periplasmic sulfate-binding protein
KPPHDEDB_01170 8e-56
KPPHDEDB_01171 8.1e-46
KPPHDEDB_01172 3e-228 2.7.7.7 L Transposase and inactivated derivatives
KPPHDEDB_01173 1.4e-161 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
KPPHDEDB_01174 4.4e-111
KPPHDEDB_01175 3e-228 2.7.7.7 L Transposase and inactivated derivatives
KPPHDEDB_01176 5.7e-155 P von Willebrand factor type A domain
KPPHDEDB_01177 2.1e-210 pldB 3.1.1.5 I Serine aminopeptidase, S33
KPPHDEDB_01178 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
KPPHDEDB_01179 2.6e-129 fhaA T Protein of unknown function (DUF2662)
KPPHDEDB_01180 5.5e-60 fhaB T Inner membrane component of T3SS, cytoplasmic domain
KPPHDEDB_01181 4.2e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
KPPHDEDB_01182 1.6e-251 rodA D Belongs to the SEDS family
KPPHDEDB_01183 4.1e-262 pbpA M penicillin-binding protein
KPPHDEDB_01184 1.3e-171 T Protein tyrosine kinase
KPPHDEDB_01185 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
KPPHDEDB_01186 1.1e-118 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
KPPHDEDB_01187 1.8e-234 srtA 3.4.22.70 M Sortase family
KPPHDEDB_01188 1.2e-106 S Bacterial protein of unknown function (DUF881)
KPPHDEDB_01189 1.9e-80 crgA D Involved in cell division
KPPHDEDB_01190 1.3e-125 gluP 3.4.21.105 S Rhomboid family
KPPHDEDB_01191 1.7e-31
KPPHDEDB_01192 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPPHDEDB_01193 1.7e-75 I Sterol carrier protein
KPPHDEDB_01194 1.3e-233 EGP Major Facilitator Superfamily
KPPHDEDB_01195 3.7e-210 2.7.13.3 T Histidine kinase
KPPHDEDB_01196 2.7e-112 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPPHDEDB_01197 5.7e-38 S Protein of unknown function (DUF3073)
KPPHDEDB_01198 1.8e-201 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPPHDEDB_01199 7.6e-310 S Amidohydrolase family
KPPHDEDB_01200 3e-176 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KPPHDEDB_01201 1.3e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPPHDEDB_01202 0.0 yjjP S Threonine/Serine exporter, ThrE
KPPHDEDB_01203 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPPHDEDB_01205 2.9e-36 ybfG M Domain of unknown function (DUF1906)
KPPHDEDB_01206 9.1e-153 P Belongs to the ABC transporter superfamily
KPPHDEDB_01207 1.5e-89 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPPHDEDB_01208 1.9e-122 appB P PFAM binding-protein-dependent transport systems inner membrane component
KPPHDEDB_01209 5.8e-191 oppA5 E family 5
KPPHDEDB_01210 1.7e-09
KPPHDEDB_01211 7.9e-32 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPPHDEDB_01212 8.6e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPPHDEDB_01213 7.4e-233 S AAA domain
KPPHDEDB_01214 2.3e-176 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01215 8.4e-165 malC P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01216 4.4e-266 G Bacterial extracellular solute-binding protein
KPPHDEDB_01218 9.8e-304 Z012_09690 P Domain of unknown function (DUF4976)
KPPHDEDB_01219 5.5e-192 K helix_turn _helix lactose operon repressor
KPPHDEDB_01220 2.1e-262 aslB C Iron-sulfur cluster-binding domain
KPPHDEDB_01221 1.5e-133 S Sulfite exporter TauE/SafE
KPPHDEDB_01222 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KPPHDEDB_01223 2.8e-236
KPPHDEDB_01224 3.1e-159 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KPPHDEDB_01225 1.1e-212 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KPPHDEDB_01226 1.4e-88 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPPHDEDB_01227 4.3e-37 yajC U Preprotein translocase subunit
KPPHDEDB_01228 3.4e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPPHDEDB_01229 5.2e-89 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPPHDEDB_01230 1.1e-96 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KPPHDEDB_01231 2e-111 yebC K transcriptional regulatory protein
KPPHDEDB_01232 7.7e-111 hit 2.7.7.53 FG HIT domain
KPPHDEDB_01233 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPPHDEDB_01239 2.2e-162 S PAC2 family
KPPHDEDB_01240 1.4e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPPHDEDB_01241 1.9e-157 G Fructosamine kinase
KPPHDEDB_01242 1e-114 L Phage integrase family
KPPHDEDB_01243 2.1e-22 N HicA toxin of bacterial toxin-antitoxin,
KPPHDEDB_01244 1.5e-18 S PFAM Uncharacterised protein family UPF0150
KPPHDEDB_01245 2.3e-44
KPPHDEDB_01246 2.7e-11 S Protein of unknown function (DUF2511)
KPPHDEDB_01248 7.1e-10
KPPHDEDB_01250 2e-222 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KPPHDEDB_01251 2.8e-148 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KPPHDEDB_01252 3.5e-28
KPPHDEDB_01254 3.1e-39
KPPHDEDB_01257 5.2e-17
KPPHDEDB_01264 4.4e-48 ssb1 L Single-stranded DNA-binding protein
KPPHDEDB_01265 5.1e-13
KPPHDEDB_01267 1.3e-84 K ParB-like nuclease domain
KPPHDEDB_01270 9.5e-63 V HNH endonuclease
KPPHDEDB_01272 9.4e-37 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KPPHDEDB_01275 6.9e-10
KPPHDEDB_01278 2.2e-09
KPPHDEDB_01279 6.8e-83 J tRNA 5'-leader removal
KPPHDEDB_01280 4.2e-52
KPPHDEDB_01281 4.3e-28
KPPHDEDB_01282 1.6e-165 S Terminase
KPPHDEDB_01283 5.8e-99 S Terminase
KPPHDEDB_01284 2.7e-168 S Phage portal protein, SPP1 Gp6-like
KPPHDEDB_01285 4.2e-100
KPPHDEDB_01286 2.2e-23
KPPHDEDB_01287 2.1e-80 S P22 coat protein-protein 5 domain protein
KPPHDEDB_01288 1.6e-60
KPPHDEDB_01289 1.3e-51
KPPHDEDB_01290 1.2e-33
KPPHDEDB_01291 6.6e-40
KPPHDEDB_01292 7.3e-84
KPPHDEDB_01293 1.7e-14
KPPHDEDB_01294 6.4e-50
KPPHDEDB_01295 4.8e-36
KPPHDEDB_01296 2.8e-191 S Phage-related minor tail protein
KPPHDEDB_01298 4.2e-68
KPPHDEDB_01299 1.9e-52
KPPHDEDB_01300 1.6e-126
KPPHDEDB_01301 7.3e-36 CP_0766 2.7.13.3 D nuclear chromosome segregation
KPPHDEDB_01302 7.7e-19
KPPHDEDB_01303 2.1e-48
KPPHDEDB_01304 1.4e-71 M Glycosyl hydrolases family 25
KPPHDEDB_01305 9.2e-24 S Putative phage holin Dp-1
KPPHDEDB_01306 4.9e-210 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPPHDEDB_01307 6.7e-180 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPPHDEDB_01308 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
KPPHDEDB_01309 4e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KPPHDEDB_01310 4.1e-216 brnQ U Component of the transport system for branched-chain amino acids
KPPHDEDB_01311 1.4e-216 mepA_6 V MatE
KPPHDEDB_01312 8.2e-253 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
KPPHDEDB_01313 5.3e-161 S Sucrose-6F-phosphate phosphohydrolase
KPPHDEDB_01314 4.2e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KPPHDEDB_01315 2.5e-34 secG U Preprotein translocase SecG subunit
KPPHDEDB_01316 4.2e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPPHDEDB_01317 7.1e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
KPPHDEDB_01318 1.2e-169 whiA K May be required for sporulation
KPPHDEDB_01319 2.3e-184 rapZ S Displays ATPase and GTPase activities
KPPHDEDB_01320 5.4e-186 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
KPPHDEDB_01321 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPPHDEDB_01322 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KPPHDEDB_01323 3.6e-25 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_01324 0.0 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_01325 6.7e-111 S Domain of unknown function (DUF4194)
KPPHDEDB_01326 7.4e-297 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_01327 2.7e-166 V MacB-like periplasmic core domain
KPPHDEDB_01328 1.4e-136 macB V ATPases associated with a variety of cellular activities
KPPHDEDB_01329 1.8e-148 M Putative peptidoglycan binding domain
KPPHDEDB_01330 1.8e-145
KPPHDEDB_01331 4.5e-115 K Transcriptional regulatory protein, C terminal
KPPHDEDB_01332 7e-124 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KPPHDEDB_01333 4.7e-12 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
KPPHDEDB_01334 5.9e-51 G ATPases associated with a variety of cellular activities
KPPHDEDB_01335 1.1e-32 S Zincin-like metallopeptidase
KPPHDEDB_01336 8.2e-162 2.1.1.72 S Protein conserved in bacteria
KPPHDEDB_01337 3.2e-127 yueD S Enoyl-(Acyl carrier protein) reductase
KPPHDEDB_01338 1.9e-300 ybiT S ABC transporter
KPPHDEDB_01339 1.6e-118 S Protein of unknown function (DUF969)
KPPHDEDB_01340 1.2e-164 S Protein of unknown function (DUF979)
KPPHDEDB_01341 8.2e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPPHDEDB_01342 3.3e-294 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPPHDEDB_01343 2.2e-69 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KPPHDEDB_01344 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KPPHDEDB_01345 8.6e-56 3.5.1.124 S DJ-1/PfpI family
KPPHDEDB_01346 1.5e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KPPHDEDB_01347 2.1e-169 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
KPPHDEDB_01348 5.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPPHDEDB_01349 1.9e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KPPHDEDB_01350 7.4e-139 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPPHDEDB_01351 6e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
KPPHDEDB_01352 1.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPPHDEDB_01353 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
KPPHDEDB_01354 1.5e-70
KPPHDEDB_01356 1e-159 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPPHDEDB_01357 4.5e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPPHDEDB_01360 2.9e-259 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
KPPHDEDB_01361 1.9e-201 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KPPHDEDB_01362 6.8e-178 3.4.14.13 M Glycosyltransferase like family 2
KPPHDEDB_01363 1.5e-265 S AI-2E family transporter
KPPHDEDB_01364 2.4e-231 epsG M Glycosyl transferase family 21
KPPHDEDB_01365 2.3e-146 natA V ATPases associated with a variety of cellular activities
KPPHDEDB_01366 3.3e-300
KPPHDEDB_01367 1.3e-255 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
KPPHDEDB_01368 4.8e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPPHDEDB_01369 1.4e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KPPHDEDB_01370 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPPHDEDB_01372 8.4e-105 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
KPPHDEDB_01373 2.6e-155 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPPHDEDB_01374 2.5e-264 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPPHDEDB_01375 2.7e-91 S Protein of unknown function (DUF3180)
KPPHDEDB_01376 8.7e-170 tesB I Thioesterase-like superfamily
KPPHDEDB_01377 0.0 yjjK S ATP-binding cassette protein, ChvD family
KPPHDEDB_01378 2.7e-20 S Protein of unknown function (DUF2975)
KPPHDEDB_01379 2.8e-26 K Cro/C1-type HTH DNA-binding domain
KPPHDEDB_01380 4.6e-07
KPPHDEDB_01381 1.8e-11 S Protein of unknown function (DUF3990)
KPPHDEDB_01382 2.1e-243 L PFAM Integrase catalytic
KPPHDEDB_01383 4.1e-144 L IstB-like ATP binding protein
KPPHDEDB_01384 9.7e-20 L HTH-like domain
KPPHDEDB_01385 5.5e-48 L PFAM Integrase catalytic
KPPHDEDB_01386 3.6e-37 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_01387 6.7e-74 L Integrase core domain
KPPHDEDB_01388 8.6e-42 L Integrase core domain
KPPHDEDB_01389 1.7e-102 XK27_02070 S Nitroreductase family
KPPHDEDB_01390 2.1e-264 EGP Major Facilitator Superfamily
KPPHDEDB_01391 1.9e-21 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
KPPHDEDB_01392 1.9e-115 K WHG domain
KPPHDEDB_01393 4.5e-112 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
KPPHDEDB_01394 3.1e-59 L PFAM Integrase catalytic
KPPHDEDB_01395 2.2e-51
KPPHDEDB_01396 2.2e-95 V ATPases associated with a variety of cellular activities
KPPHDEDB_01397 1.9e-261 V FtsX-like permease family
KPPHDEDB_01398 1.5e-59 K Virulence activator alpha C-term
KPPHDEDB_01400 7.8e-292 EGP Major Facilitator Superfamily
KPPHDEDB_01402 1.1e-175 glkA 2.7.1.2 G ROK family
KPPHDEDB_01403 2.6e-63 EGP Major facilitator superfamily
KPPHDEDB_01404 1.1e-163 dkgB S Oxidoreductase, aldo keto reductase family protein
KPPHDEDB_01405 1.1e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPPHDEDB_01406 2.5e-144
KPPHDEDB_01407 4.5e-22 EGP Major facilitator Superfamily
KPPHDEDB_01408 4.1e-23 EGP Major Facilitator Superfamily
KPPHDEDB_01409 1.8e-68 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
KPPHDEDB_01410 1.8e-226 xylR GK ROK family
KPPHDEDB_01412 1.3e-36 rpmE J Binds the 23S rRNA
KPPHDEDB_01413 9e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPPHDEDB_01414 3.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPPHDEDB_01415 2.8e-200 livK E Receptor family ligand binding region
KPPHDEDB_01416 2.8e-17 rex2 A Ribonuclease H-like protein
KPPHDEDB_01421 6.2e-09
KPPHDEDB_01424 1.8e-30 K RNA polymerase II activating transcription factor binding
KPPHDEDB_01429 1.9e-248 V N-6 DNA Methylase
KPPHDEDB_01430 3.9e-57 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KPPHDEDB_01432 2.6e-51
KPPHDEDB_01433 2e-29 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KPPHDEDB_01434 4.5e-39 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
KPPHDEDB_01436 2.6e-63 L Helix-turn-helix domain
KPPHDEDB_01440 1.6e-28 flgJ S pathogenesis
KPPHDEDB_01442 3.7e-29 ydhQ 2.7.11.1 MU cell adhesion
KPPHDEDB_01443 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KPPHDEDB_01444 8.4e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
KPPHDEDB_01445 2.7e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
KPPHDEDB_01446 1.9e-235 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KPPHDEDB_01447 1.1e-192 S alpha beta
KPPHDEDB_01448 1.2e-82 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KPPHDEDB_01449 3.1e-225 ilvE 2.6.1.42 E Amino-transferase class IV
KPPHDEDB_01450 1.3e-109 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
KPPHDEDB_01451 4.6e-97 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPPHDEDB_01452 1.6e-20 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPPHDEDB_01453 1.1e-184 nusA K Participates in both transcription termination and antitermination
KPPHDEDB_01454 1.2e-124
KPPHDEDB_01455 1.4e-243 G Bacterial extracellular solute-binding protein
KPPHDEDB_01456 6.3e-174 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01457 1.4e-159 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01458 3.3e-15 L Integrase core domain
KPPHDEDB_01460 2.5e-218 S Psort location Cytoplasmic, score
KPPHDEDB_01461 1.1e-149 E Transglutaminase/protease-like homologues
KPPHDEDB_01462 0.0 gcs2 S A circularly permuted ATPgrasp
KPPHDEDB_01463 6e-12 L Helix-turn-helix domain
KPPHDEDB_01464 6.8e-87 V Abi-like protein
KPPHDEDB_01465 7.7e-75 L IstB-like ATP binding protein
KPPHDEDB_01466 9.4e-18 L PFAM Integrase catalytic
KPPHDEDB_01468 4.9e-180 yocS S SBF-like CPA transporter family (DUF4137)
KPPHDEDB_01470 1.1e-189 ltaE 4.1.2.48 E Beta-eliminating lyase
KPPHDEDB_01471 3.2e-209 M Glycosyl transferase 4-like domain
KPPHDEDB_01472 1.3e-189 mtnE 2.6.1.83 E Aminotransferase class I and II
KPPHDEDB_01473 6e-226 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KPPHDEDB_01474 3.2e-62 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPPHDEDB_01475 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KPPHDEDB_01476 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
KPPHDEDB_01477 1.1e-158 I alpha/beta hydrolase fold
KPPHDEDB_01478 7.2e-253 Q D-alanine [D-alanyl carrier protein] ligase activity
KPPHDEDB_01479 9e-108 Q D-alanine [D-alanyl carrier protein] ligase activity
KPPHDEDB_01480 2.6e-100 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
KPPHDEDB_01481 1.7e-170 hipA 2.7.11.1 S HipA N-terminal domain
KPPHDEDB_01482 5.4e-10 C Aldo/keto reductase family
KPPHDEDB_01483 6.2e-49 C Aldo/keto reductase family
KPPHDEDB_01484 1.6e-32
KPPHDEDB_01485 2.8e-267 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
KPPHDEDB_01486 2e-35 3.5.2.6 V Beta-lactamase
KPPHDEDB_01487 1.2e-39 S Phosphotransferase enzyme family
KPPHDEDB_01488 4.8e-48
KPPHDEDB_01489 1.8e-61 V ATPases associated with a variety of cellular activities
KPPHDEDB_01490 1.1e-46 CP ABC-2 family transporter protein
KPPHDEDB_01491 1.9e-94 1.6.5.5 C alcohol dehydrogenase
KPPHDEDB_01492 7.3e-123 L Transposase
KPPHDEDB_01493 6.1e-35 L Transposase
KPPHDEDB_01494 1.3e-186 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_01495 4.5e-192 3.3.1.1 H S-adenosyl-L-homocysteine hydrolase, NAD binding domain
KPPHDEDB_01496 5.4e-240 ssnA 3.5.4.40 F Amidohydrolase family
KPPHDEDB_01497 1.8e-65 MA20_39615 S Cupin superfamily (DUF985)
KPPHDEDB_01498 1.3e-127 ET Bacterial periplasmic substrate-binding proteins
KPPHDEDB_01499 1.9e-122 E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01500 4.2e-120 glnQ 3.6.3.21 E AAA domain, putative AbiEii toxin, Type IV TA system
KPPHDEDB_01501 1.9e-286 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPPHDEDB_01502 3.9e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KPPHDEDB_01503 2e-233 purD 6.3.4.13 F Belongs to the GARS family
KPPHDEDB_01504 7.6e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
KPPHDEDB_01505 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KPPHDEDB_01506 4.7e-147 P Zinc-uptake complex component A periplasmic
KPPHDEDB_01507 4.7e-100 S cobalamin synthesis protein
KPPHDEDB_01508 3.9e-29 rpmB J Ribosomal L28 family
KPPHDEDB_01509 1.4e-20 rpmG J Ribosomal protein L33
KPPHDEDB_01510 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPPHDEDB_01511 9.7e-34 rpmE2 J Ribosomal protein L31
KPPHDEDB_01512 1.1e-14 rpmJ J Ribosomal protein L36
KPPHDEDB_01513 2.6e-19 J Ribosomal L32p protein family
KPPHDEDB_01514 1e-25 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KPPHDEDB_01516 1.5e-171 ycgR S Predicted permease
KPPHDEDB_01517 1.9e-138 S TIGRFAM TIGR03943 family protein
KPPHDEDB_01518 1.1e-84 zur P Ferric uptake regulator family
KPPHDEDB_01519 7.9e-63
KPPHDEDB_01520 2e-46 tetR K Transcriptional regulator C-terminal region
KPPHDEDB_01521 2.9e-18 XK27_06785 V ABC transporter
KPPHDEDB_01522 2.2e-83 ylbB V FtsX-like permease family
KPPHDEDB_01523 1.2e-68 zur P Belongs to the Fur family
KPPHDEDB_01524 1.2e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPPHDEDB_01525 2.1e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPPHDEDB_01526 3e-176 adh3 C Zinc-binding dehydrogenase
KPPHDEDB_01527 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPPHDEDB_01528 2.4e-252 macB_8 V MacB-like periplasmic core domain
KPPHDEDB_01529 1.6e-131 M Conserved repeat domain
KPPHDEDB_01530 3.4e-122 V ATPases associated with a variety of cellular activities
KPPHDEDB_01532 2.1e-203 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPPHDEDB_01533 7.5e-155 K Helix-turn-helix domain, rpiR family
KPPHDEDB_01534 0.0 G Alpha-L-arabinofuranosidase C-terminal domain
KPPHDEDB_01535 5.1e-22
KPPHDEDB_01538 0.0 EK Alanine-glyoxylate amino-transferase
KPPHDEDB_01539 9.6e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KPPHDEDB_01540 2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KPPHDEDB_01541 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPPHDEDB_01542 8.6e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
KPPHDEDB_01543 7e-248 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPPHDEDB_01544 1.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
KPPHDEDB_01545 7.9e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPPHDEDB_01546 1.8e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPPHDEDB_01547 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KPPHDEDB_01548 6.5e-296 enhA_2 S L,D-transpeptidase catalytic domain
KPPHDEDB_01549 1.7e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KPPHDEDB_01550 9.1e-91 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
KPPHDEDB_01552 1.2e-170 EGP Major Facilitator Superfamily
KPPHDEDB_01553 1.8e-149 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KPPHDEDB_01554 9.3e-09 sapF E ATPases associated with a variety of cellular activities
KPPHDEDB_01555 1.3e-122 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
KPPHDEDB_01556 1.5e-124 EP Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01557 7.8e-161 P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01558 2.4e-282 E ABC transporter, substrate-binding protein, family 5
KPPHDEDB_01559 7.7e-244 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPPHDEDB_01560 9.3e-141 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KPPHDEDB_01561 1.1e-264 G Bacterial extracellular solute-binding protein
KPPHDEDB_01563 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KPPHDEDB_01564 7.6e-116 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
KPPHDEDB_01565 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPPHDEDB_01566 1.3e-148 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
KPPHDEDB_01567 5.4e-149 yecS E Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01568 7.7e-169 pknD ET ABC transporter, substrate-binding protein, family 3
KPPHDEDB_01569 1.3e-144 pknD ET ABC transporter, substrate-binding protein, family 3
KPPHDEDB_01570 1.8e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPPHDEDB_01571 4.8e-156 usp 3.5.1.28 CBM50 D CHAP domain protein
KPPHDEDB_01572 5.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
KPPHDEDB_01573 1.7e-176 ftsE D Cell division ATP-binding protein FtsE
KPPHDEDB_01574 7.1e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPPHDEDB_01575 1.1e-253 S Domain of unknown function (DUF4143)
KPPHDEDB_01576 3.1e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
KPPHDEDB_01577 1.2e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPPHDEDB_01578 8.4e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPPHDEDB_01579 1.2e-97 ugpA P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01580 1.7e-97 ugpE G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01581 2.3e-158 ugpB G Bacterial extracellular solute-binding protein
KPPHDEDB_01582 6.8e-100 ugpQ 3.1.4.46 C Domain of unknown function
KPPHDEDB_01583 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
KPPHDEDB_01584 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPPHDEDB_01585 1e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPPHDEDB_01586 1.7e-131 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPPHDEDB_01587 5.6e-226 G Major Facilitator Superfamily
KPPHDEDB_01588 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KPPHDEDB_01589 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
KPPHDEDB_01590 6.6e-257 KLT Protein tyrosine kinase
KPPHDEDB_01591 0.0 S Fibronectin type 3 domain
KPPHDEDB_01592 1.4e-176 S ATPase family associated with various cellular activities (AAA)
KPPHDEDB_01593 8.2e-224 S Protein of unknown function DUF58
KPPHDEDB_01594 0.0 E Transglutaminase-like superfamily
KPPHDEDB_01595 9.3e-26 3.1.3.16 T Sigma factor PP2C-like phosphatases
KPPHDEDB_01596 6.1e-69 B Belongs to the OprB family
KPPHDEDB_01597 7.6e-88 T Forkhead associated domain
KPPHDEDB_01598 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPPHDEDB_01599 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPPHDEDB_01600 3.7e-107
KPPHDEDB_01601 3.6e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
KPPHDEDB_01602 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPPHDEDB_01603 6.8e-251 S UPF0210 protein
KPPHDEDB_01604 1.9e-43 gcvR T Belongs to the UPF0237 family
KPPHDEDB_01606 3.8e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
KPPHDEDB_01607 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
KPPHDEDB_01608 6.9e-122 glpR K DeoR C terminal sensor domain
KPPHDEDB_01609 1.3e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KPPHDEDB_01610 2.2e-233 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
KPPHDEDB_01611 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KPPHDEDB_01612 2.6e-132 glxR K helix_turn_helix, cAMP Regulatory protein
KPPHDEDB_01613 2e-197 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
KPPHDEDB_01614 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KPPHDEDB_01615 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
KPPHDEDB_01616 2.1e-249 S Uncharacterized conserved protein (DUF2183)
KPPHDEDB_01617 1.2e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KPPHDEDB_01618 1.7e-227 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KPPHDEDB_01619 3.5e-160 mhpC I Alpha/beta hydrolase family
KPPHDEDB_01620 7.3e-126 F Domain of unknown function (DUF4916)
KPPHDEDB_01621 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
KPPHDEDB_01622 5e-171 S G5
KPPHDEDB_01623 1.1e-18 hipB K Helix-turn-helix XRE-family like proteins
KPPHDEDB_01624 2.6e-133 2.7.11.1 S HipA-like C-terminal domain
KPPHDEDB_01625 2.9e-140
KPPHDEDB_01626 7.5e-237 wcoI DM Psort location CytoplasmicMembrane, score
KPPHDEDB_01628 2.6e-138
KPPHDEDB_01629 1.7e-11 S Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01630 6.2e-165 dprA LU DNA recombination-mediator protein A
KPPHDEDB_01631 7.5e-160 S competence protein
KPPHDEDB_01632 7.3e-29 L Transposase
KPPHDEDB_01633 4.1e-159 L Transposase
KPPHDEDB_01634 1.1e-81 S Polysaccharide biosynthesis protein
KPPHDEDB_01635 8.9e-28
KPPHDEDB_01636 1.8e-76 L Transposase, Mutator family
KPPHDEDB_01637 1.1e-11 M Glycosyltransferase like family 2
KPPHDEDB_01638 3e-53 cps3B S Glycosyltransferase like family 2
KPPHDEDB_01639 3.4e-88 M Glycosyl transferases group 1
KPPHDEDB_01640 6.4e-183 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_01641 1.8e-223 glf 5.4.99.9 M UDP-galactopyranose mutase
KPPHDEDB_01642 6.6e-80 tnp7109-21 L Integrase core domain
KPPHDEDB_01643 4.9e-47 tnp7109-21 L Integrase core domain
KPPHDEDB_01644 5.1e-40 L Transposase
KPPHDEDB_01645 2.5e-96 cps1D M Domain of unknown function (DUF4422)
KPPHDEDB_01646 6.5e-17 S Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01647 2e-10 S Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01648 1.1e-38 S Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01649 6.4e-61 3.1.3.48 T Low molecular weight phosphatase family
KPPHDEDB_01651 4.6e-114 S Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01652 6.3e-108 3.1.3.48 T Low molecular weight phosphatase family
KPPHDEDB_01653 3.9e-126 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KPPHDEDB_01654 3e-106 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KPPHDEDB_01655 1.8e-113 E Branched-chain amino acid ATP-binding cassette transporter
KPPHDEDB_01656 1.1e-171 livM U Belongs to the binding-protein-dependent transport system permease family
KPPHDEDB_01657 1.7e-52 U Belongs to the binding-protein-dependent transport system permease family
KPPHDEDB_01660 1.4e-93 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KPPHDEDB_01661 5.5e-41 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KPPHDEDB_01664 1.6e-95
KPPHDEDB_01665 4.6e-250 corC S CBS domain
KPPHDEDB_01666 8.8e-101 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPPHDEDB_01667 6.3e-213 phoH T PhoH-like protein
KPPHDEDB_01668 2.6e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
KPPHDEDB_01669 3.6e-143 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KPPHDEDB_01671 1.4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
KPPHDEDB_01672 2.9e-240 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPPHDEDB_01673 2.7e-111 yitW S Iron-sulfur cluster assembly protein
KPPHDEDB_01674 5.8e-100 iscU C SUF system FeS assembly protein, NifU family
KPPHDEDB_01675 2.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPPHDEDB_01676 9.2e-144 sufC O FeS assembly ATPase SufC
KPPHDEDB_01677 7.3e-236 sufD O FeS assembly protein SufD
KPPHDEDB_01678 4.3e-291 sufB O FeS assembly protein SufB
KPPHDEDB_01679 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPPHDEDB_01680 2.7e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KPPHDEDB_01681 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPPHDEDB_01682 5.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPPHDEDB_01683 2.6e-77 3.4.23.43 S Type IV leader peptidase family
KPPHDEDB_01684 3.3e-201 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPPHDEDB_01685 5.1e-78 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPPHDEDB_01686 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPPHDEDB_01687 1.6e-35
KPPHDEDB_01688 2.6e-62 WQ51_05790 S Bacterial protein of unknown function (DUF948)
KPPHDEDB_01689 1.9e-129 pgm3 G Phosphoglycerate mutase family
KPPHDEDB_01690 1.2e-48 relB L RelB antitoxin
KPPHDEDB_01691 3e-65 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPPHDEDB_01692 1.2e-111 E Transglutaminase-like superfamily
KPPHDEDB_01693 9.3e-43 sdpI S SdpI/YhfL protein family
KPPHDEDB_01694 1.8e-89 3.5.4.5 F cytidine deaminase activity
KPPHDEDB_01695 1.6e-151 S Peptidase C26
KPPHDEDB_01696 4.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPPHDEDB_01697 7.6e-135 lolD V ABC transporter
KPPHDEDB_01698 1.6e-214 V FtsX-like permease family
KPPHDEDB_01699 1.8e-63 S Domain of unknown function (DUF4418)
KPPHDEDB_01700 0.0 pcrA 3.6.4.12 L DNA helicase
KPPHDEDB_01701 1.4e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPPHDEDB_01702 1.6e-239 pbuX F Permease family
KPPHDEDB_01703 2.8e-31 yozG K Cro/C1-type HTH DNA-binding domain
KPPHDEDB_01704 3e-38 S Protein of unknown function (DUF2975)
KPPHDEDB_01705 5.3e-162 M pfam nlp p60
KPPHDEDB_01706 1e-66 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPPHDEDB_01707 2.9e-108 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
KPPHDEDB_01708 2.4e-110 3.4.13.21 E Peptidase family S51
KPPHDEDB_01709 2.5e-196
KPPHDEDB_01710 3e-50 E lipolytic protein G-D-S-L family
KPPHDEDB_01711 7.6e-42 E GDSL-like Lipase/Acylhydrolase family
KPPHDEDB_01712 1.8e-90 K Helix-turn-helix domain
KPPHDEDB_01713 1.2e-103 S PIN domain
KPPHDEDB_01714 5e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPPHDEDB_01715 1.9e-248 V ABC-2 family transporter protein
KPPHDEDB_01716 1.1e-223 V ABC-2 family transporter protein
KPPHDEDB_01717 2.9e-187 V ATPases associated with a variety of cellular activities
KPPHDEDB_01718 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
KPPHDEDB_01719 2.8e-225 T Histidine kinase
KPPHDEDB_01720 2e-107 K helix_turn_helix, Lux Regulon
KPPHDEDB_01721 2.1e-114 MA20_27875 P Protein of unknown function DUF47
KPPHDEDB_01722 9.7e-57 pit P Phosphate transporter family
KPPHDEDB_01723 2.7e-257 nplT G Alpha amylase, catalytic domain
KPPHDEDB_01724 2.1e-33 EGP Major Facilitator Superfamily
KPPHDEDB_01725 2.1e-12 EGP Major Facilitator Superfamily
KPPHDEDB_01726 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
KPPHDEDB_01728 9.3e-234 rutG F Permease family
KPPHDEDB_01729 3e-161 3.1.3.73 G Phosphoglycerate mutase family
KPPHDEDB_01730 1.3e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
KPPHDEDB_01731 1.2e-234 EGP Major facilitator Superfamily
KPPHDEDB_01734 3.3e-131 S Sulfite exporter TauE/SafE
KPPHDEDB_01736 1.7e-35 feoA P FeoA
KPPHDEDB_01737 3.3e-87 S Helix-turn-helix
KPPHDEDB_01738 4.8e-13 M Excalibur calcium-binding domain
KPPHDEDB_01739 2.8e-197 S Short C-terminal domain
KPPHDEDB_01740 9.2e-39
KPPHDEDB_01741 4.2e-225
KPPHDEDB_01742 4.6e-76 K Psort location Cytoplasmic, score
KPPHDEDB_01743 3.2e-282 KLT Protein tyrosine kinase
KPPHDEDB_01744 5.1e-260 EGP Transmembrane secretion effector
KPPHDEDB_01745 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
KPPHDEDB_01746 2.2e-11
KPPHDEDB_01747 1.3e-120 K Bacterial regulatory proteins, tetR family
KPPHDEDB_01748 1.2e-217 G Transmembrane secretion effector
KPPHDEDB_01749 1.2e-17 higA K Helix-turn-helix
KPPHDEDB_01750 7.4e-244 S HipA-like C-terminal domain
KPPHDEDB_01751 1.1e-37 L RelB antitoxin
KPPHDEDB_01752 6.5e-51 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KPPHDEDB_01753 4.3e-64 S Cupin 2, conserved barrel domain protein
KPPHDEDB_01754 6.6e-159 ksgA 2.1.1.182 J Methyltransferase domain
KPPHDEDB_01755 5.3e-60 yccF S Inner membrane component domain
KPPHDEDB_01756 3.2e-231 XK27_00240 K Fic/DOC family
KPPHDEDB_01757 1.4e-26 2.7.7.7 L Transposase, Mutator family
KPPHDEDB_01758 0.0 drrC L ABC transporter
KPPHDEDB_01759 1.3e-241 V MatE
KPPHDEDB_01760 3.4e-26 S rRNA binding
KPPHDEDB_01761 3.3e-163 K Arac family
KPPHDEDB_01762 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPPHDEDB_01763 4.5e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPPHDEDB_01764 3.5e-261 pip 3.4.11.5 S alpha/beta hydrolase fold
KPPHDEDB_01765 0.0 tcsS2 T Histidine kinase
KPPHDEDB_01766 1.8e-127 K helix_turn_helix, Lux Regulon
KPPHDEDB_01767 0.0 MV MacB-like periplasmic core domain
KPPHDEDB_01768 2e-145 V ABC transporter, ATP-binding protein
KPPHDEDB_01769 2.1e-249 metY 2.5.1.49 E Aminotransferase class-V
KPPHDEDB_01770 3.1e-164 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KPPHDEDB_01771 4e-92 yraN L Belongs to the UPF0102 family
KPPHDEDB_01772 8.3e-290 comM O Magnesium chelatase, subunit ChlI C-terminal
KPPHDEDB_01773 2.9e-304 dprA 5.99.1.2 LU DNA recombination-mediator protein A
KPPHDEDB_01774 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
KPPHDEDB_01775 5.4e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
KPPHDEDB_01776 4.3e-110 safC S O-methyltransferase
KPPHDEDB_01777 8.8e-149 fmt2 3.2.2.10 S Belongs to the LOG family
KPPHDEDB_01778 8.2e-215 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KPPHDEDB_01781 1.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPPHDEDB_01782 8e-123 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPPHDEDB_01783 3.8e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPPHDEDB_01784 2.1e-53
KPPHDEDB_01785 3.7e-231 clcA_2 P Voltage gated chloride channel
KPPHDEDB_01786 3.8e-233 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPPHDEDB_01787 6e-249 rnd 3.1.13.5 J 3'-5' exonuclease
KPPHDEDB_01788 4.7e-122 S Protein of unknown function (DUF3000)
KPPHDEDB_01789 7.4e-174 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPPHDEDB_01790 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KPPHDEDB_01791 8.5e-34
KPPHDEDB_01792 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KPPHDEDB_01793 1.4e-225 S Peptidase dimerisation domain
KPPHDEDB_01794 2.1e-112 metI P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01795 1e-218 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPPHDEDB_01796 1.4e-168 metQ P NLPA lipoprotein
KPPHDEDB_01797 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KPPHDEDB_01798 7.4e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KPPHDEDB_01799 1e-265 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_01800 1.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPPHDEDB_01802 5.4e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPPHDEDB_01803 2.2e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPPHDEDB_01804 9.8e-129 3.1.3.85 G Phosphoglycerate mutase family
KPPHDEDB_01807 3.3e-114 L Phage integrase family
KPPHDEDB_01812 1.3e-50 traA D ftsk spoiiie
KPPHDEDB_01813 1.6e-13
KPPHDEDB_01814 2.5e-38
KPPHDEDB_01815 4.8e-92
KPPHDEDB_01816 5.8e-24 K Helix-turn-helix XRE-family like proteins
KPPHDEDB_01817 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KPPHDEDB_01818 1.4e-226 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPPHDEDB_01819 8.9e-248 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPPHDEDB_01820 2.6e-198 ykiI
KPPHDEDB_01821 2e-14
KPPHDEDB_01823 4.4e-13 K Putative zinc ribbon domain
KPPHDEDB_01824 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KPPHDEDB_01825 6.3e-125 3.6.1.13 L NUDIX domain
KPPHDEDB_01826 1.3e-176 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
KPPHDEDB_01827 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPPHDEDB_01828 2.4e-120 pdtaR T Response regulator receiver domain protein
KPPHDEDB_01830 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
KPPHDEDB_01831 1.2e-172 terC P Integral membrane protein, TerC family
KPPHDEDB_01832 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPPHDEDB_01833 7.4e-55 2.1.1.80, 3.1.1.61 T Histidine kinase
KPPHDEDB_01834 8e-64 K helix_turn_helix, Lux Regulon
KPPHDEDB_01835 6.1e-144 XK27_10205
KPPHDEDB_01836 4.5e-72 V ABC transporter
KPPHDEDB_01837 3e-73 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPPHDEDB_01838 2.3e-252 rpsA J Ribosomal protein S1
KPPHDEDB_01839 4.8e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPPHDEDB_01840 4.1e-172 P Zinc-uptake complex component A periplasmic
KPPHDEDB_01841 1.2e-163 znuC P ATPases associated with a variety of cellular activities
KPPHDEDB_01842 1.5e-136 znuB U ABC 3 transport family
KPPHDEDB_01843 1e-90 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KPPHDEDB_01844 1.6e-100 carD K CarD-like/TRCF domain
KPPHDEDB_01845 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KPPHDEDB_01846 5e-128 T Response regulator receiver domain protein
KPPHDEDB_01847 5.8e-189 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPPHDEDB_01848 7.4e-62 KT Peptidase S24-like
KPPHDEDB_01849 3.4e-57 ctsW S Phosphoribosyl transferase domain
KPPHDEDB_01850 7.5e-149 cof 5.2.1.8 T Eukaryotic phosphomannomutase
KPPHDEDB_01851 3.3e-64 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
KPPHDEDB_01852 3.2e-265
KPPHDEDB_01853 0.0 S Glycosyl transferase, family 2
KPPHDEDB_01854 4.7e-56 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KPPHDEDB_01855 1e-164 K Cell envelope-related transcriptional attenuator domain
KPPHDEDB_01856 0.0 D FtsK/SpoIIIE family
KPPHDEDB_01857 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KPPHDEDB_01858 1.9e-278 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPPHDEDB_01859 5.1e-149 yplQ S Haemolysin-III related
KPPHDEDB_01860 5.7e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPPHDEDB_01861 8.9e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
KPPHDEDB_01862 2.9e-276 sdaA 4.3.1.17 E Serine dehydratase alpha chain
KPPHDEDB_01863 6e-92
KPPHDEDB_01865 1.5e-178 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KPPHDEDB_01866 1.8e-101 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
KPPHDEDB_01867 4.8e-76 divIC D Septum formation initiator
KPPHDEDB_01868 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPPHDEDB_01869 4.3e-180 1.1.1.65 C Aldo/keto reductase family
KPPHDEDB_01870 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPPHDEDB_01871 2e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPPHDEDB_01872 1.5e-71 S PIN domain
KPPHDEDB_01873 7.3e-47 S RelB antitoxin
KPPHDEDB_01874 2e-88 2.3.1.183 M Acetyltransferase (GNAT) domain
KPPHDEDB_01875 0.0 S Uncharacterised protein family (UPF0182)
KPPHDEDB_01876 1.6e-208 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
KPPHDEDB_01877 3.8e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPPHDEDB_01878 7.9e-100
KPPHDEDB_01879 1.1e-231 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPPHDEDB_01880 1.9e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPPHDEDB_01881 4.3e-283 thrC 4.2.3.1 E Threonine synthase N terminus
KPPHDEDB_01882 3.1e-196 S Protein of unknown function (DUF1648)
KPPHDEDB_01883 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
KPPHDEDB_01884 3.3e-24 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KPPHDEDB_01885 8.5e-73 S ABC-2 family transporter protein
KPPHDEDB_01886 2e-121 S ABC-2 family transporter protein
KPPHDEDB_01887 2.1e-74 V ATPases associated with a variety of cellular activities
KPPHDEDB_01888 1.8e-47 V ATPases associated with a variety of cellular activities
KPPHDEDB_01889 1.6e-56 K helix_turn_helix gluconate operon transcriptional repressor
KPPHDEDB_01890 1.9e-36 K helix_turn_helix, Lux Regulon
KPPHDEDB_01891 1.2e-31 2.7.13.3 T Histidine kinase
KPPHDEDB_01892 2e-52 EGP Major facilitator Superfamily
KPPHDEDB_01893 1.1e-66 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KPPHDEDB_01894 1.3e-111 S Haloacid dehalogenase-like hydrolase
KPPHDEDB_01895 2.5e-311 recN L May be involved in recombinational repair of damaged DNA
KPPHDEDB_01896 9e-184 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPPHDEDB_01897 4e-95
KPPHDEDB_01898 2e-138 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KPPHDEDB_01900 2e-194 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KPPHDEDB_01901 3.9e-134 L Tetratricopeptide repeat
KPPHDEDB_01902 2.8e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPPHDEDB_01903 3.3e-138 S Putative ABC-transporter type IV
KPPHDEDB_01904 8.9e-98 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KPPHDEDB_01905 1.3e-55 M1-798 P Rhodanese Homology Domain
KPPHDEDB_01906 2e-146 moeB 2.7.7.80 H ThiF family
KPPHDEDB_01907 1.1e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KPPHDEDB_01908 2.1e-28 thiS 2.8.1.10 H ThiS family
KPPHDEDB_01909 7.5e-280 argH 4.3.2.1 E argininosuccinate lyase
KPPHDEDB_01910 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KPPHDEDB_01911 4.5e-83 argR K Regulates arginine biosynthesis genes
KPPHDEDB_01912 8.6e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPPHDEDB_01913 1.3e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
KPPHDEDB_01914 2.8e-168 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KPPHDEDB_01915 8.2e-213 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KPPHDEDB_01916 7.2e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KPPHDEDB_01917 1.5e-94
KPPHDEDB_01918 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
KPPHDEDB_01919 2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPPHDEDB_01920 2e-163 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPPHDEDB_01921 6.5e-148 cbiQ P Cobalt transport protein
KPPHDEDB_01922 1.4e-273 ykoD P ATPases associated with a variety of cellular activities
KPPHDEDB_01923 3.1e-107 ykoE S ABC-type cobalt transport system, permease component
KPPHDEDB_01924 1.7e-257 argE E Peptidase dimerisation domain
KPPHDEDB_01925 3.8e-108 S Protein of unknown function (DUF3043)
KPPHDEDB_01926 1.4e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPPHDEDB_01927 4.7e-140 S Domain of unknown function (DUF4191)
KPPHDEDB_01928 5e-281 glnA 6.3.1.2 E glutamine synthetase
KPPHDEDB_01929 1.4e-23 uidA 3.2.1.31 G Glycosyl hydrolases family 2, TIM barrel domain
KPPHDEDB_01930 1.2e-173 S Membrane transport protein
KPPHDEDB_01931 1e-74 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KPPHDEDB_01932 3.3e-84 laaE K Transcriptional regulator PadR-like family
KPPHDEDB_01933 3.3e-110 magIII L endonuclease III
KPPHDEDB_01934 2e-242 vbsD V MatE
KPPHDEDB_01935 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPPHDEDB_01936 1e-75 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPPHDEDB_01937 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
KPPHDEDB_01938 9.3e-94 S AAA domain
KPPHDEDB_01939 3.4e-132 C FMN binding
KPPHDEDB_01940 5.4e-97 effR K helix_turn_helix multiple antibiotic resistance protein
KPPHDEDB_01941 3.4e-11 S AAA domain
KPPHDEDB_01942 8.5e-190 K helix_turn _helix lactose operon repressor
KPPHDEDB_01943 1.8e-162 P Phosphate transporter family
KPPHDEDB_01944 3e-163 ugpA P Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01945 8.9e-142 ugpE G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_01946 2.2e-238 ugpB G Bacterial extracellular solute-binding protein
KPPHDEDB_01947 6.4e-170 ugpQ 3.1.4.46 C Domain of unknown function
KPPHDEDB_01948 7.6e-109 P Protein of unknown function DUF47
KPPHDEDB_01949 7.4e-258 S Domain of unknown function (DUF4143)
KPPHDEDB_01950 1.3e-190 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KPPHDEDB_01951 3e-16 K MerR family regulatory protein
KPPHDEDB_01952 1.4e-09 K MerR family regulatory protein
KPPHDEDB_01953 3.8e-88 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPPHDEDB_01954 2.8e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPPHDEDB_01955 1.2e-32 S Psort location CytoplasmicMembrane, score
KPPHDEDB_01956 8.6e-185 MA20_14895 S Conserved hypothetical protein 698
KPPHDEDB_01957 7.8e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
KPPHDEDB_01958 6e-100 tmp1 S Domain of unknown function (DUF4391)
KPPHDEDB_01959 6.8e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPPHDEDB_01960 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPPHDEDB_01961 1.6e-79 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPPHDEDB_01962 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPPHDEDB_01963 3.5e-125 S COG0433 Predicted ATPase
KPPHDEDB_01964 1.5e-49
KPPHDEDB_01966 1.1e-40 D protein tyrosine kinase activity
KPPHDEDB_01969 1.2e-23 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
KPPHDEDB_01971 2e-76 L endonuclease I
KPPHDEDB_01972 2.7e-41 M NlpC/P60 family
KPPHDEDB_01973 2.9e-43 usp 3.5.1.28 CBM50 S CHAP domain
KPPHDEDB_01974 2.3e-46
KPPHDEDB_01977 1.6e-59 NU Tfp pilus assembly protein FimV
KPPHDEDB_01978 0.0 E Sodium:solute symporter family
KPPHDEDB_01979 6.8e-43
KPPHDEDB_01980 3.6e-89 G transmembrane transporter activity
KPPHDEDB_01981 2.5e-86 S L,D-transpeptidase catalytic domain
KPPHDEDB_01983 2.7e-308 cotH M CotH kinase protein
KPPHDEDB_01984 1.2e-267 pelG S Putative exopolysaccharide Exporter (EPS-E)
KPPHDEDB_01985 4.7e-279 pelF GT4 M Domain of unknown function (DUF3492)
KPPHDEDB_01986 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KPPHDEDB_01987 1e-162
KPPHDEDB_01988 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KPPHDEDB_01989 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
KPPHDEDB_01990 8.6e-86 K Bacterial regulatory proteins, tetR family
KPPHDEDB_01991 2.6e-40
KPPHDEDB_01992 5.3e-231 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KPPHDEDB_01993 2.6e-70 S Nucleotidyltransferase substrate binding protein like
KPPHDEDB_01994 3.6e-45 S Nucleotidyltransferase domain
KPPHDEDB_01995 7.3e-64 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
KPPHDEDB_01996 6.5e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
KPPHDEDB_01997 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
KPPHDEDB_01998 1.1e-143 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPPHDEDB_01999 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
KPPHDEDB_02000 1.7e-254 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPPHDEDB_02001 3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPPHDEDB_02002 6.4e-234 S peptidyl-serine autophosphorylation
KPPHDEDB_02003 1.4e-92 ywrO 1.6.5.2 S Flavodoxin-like fold
KPPHDEDB_02004 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KPPHDEDB_02005 3.8e-75 F Nucleoside 2-deoxyribosyltransferase
KPPHDEDB_02006 1.1e-10 K Acetyltransferase (GNAT) domain
KPPHDEDB_02008 2e-192 S Endonuclease/Exonuclease/phosphatase family
KPPHDEDB_02009 3.1e-11 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KPPHDEDB_02010 6.4e-08 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KPPHDEDB_02011 7.4e-233 aspB E Aminotransferase class-V
KPPHDEDB_02012 9.4e-200 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
KPPHDEDB_02013 1.4e-84 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KPPHDEDB_02014 5e-34 XK27_03610 K Acetyltransferase (GNAT) domain
KPPHDEDB_02015 1.1e-33
KPPHDEDB_02016 7.4e-80 S PFAM Uncharacterised protein family UPF0150
KPPHDEDB_02017 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
KPPHDEDB_02018 2.2e-212 K WYL domain
KPPHDEDB_02019 2.2e-145 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KPPHDEDB_02020 1.9e-247 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
KPPHDEDB_02021 9.2e-152 map 3.4.11.18 E Methionine aminopeptidase
KPPHDEDB_02022 3.3e-98 S Short repeat of unknown function (DUF308)
KPPHDEDB_02023 0.0 pepO 3.4.24.71 O Peptidase family M13
KPPHDEDB_02024 2.3e-51 L Single-strand binding protein family
KPPHDEDB_02025 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPPHDEDB_02026 2e-28 GT87 NU Tfp pilus assembly protein FimV
KPPHDEDB_02027 7.5e-269 recD2 3.6.4.12 L PIF1-like helicase
KPPHDEDB_02028 4.7e-117 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KPPHDEDB_02029 7.6e-291 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KPPHDEDB_02030 1.3e-203 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
KPPHDEDB_02031 1.8e-119 ywlC 2.7.7.87 J Belongs to the SUA5 family
KPPHDEDB_02032 1.5e-121 livF E ATPases associated with a variety of cellular activities
KPPHDEDB_02033 3.3e-107 L PFAM Integrase catalytic
KPPHDEDB_02034 3.9e-240 EGP Major facilitator Superfamily
KPPHDEDB_02035 2.9e-34 D Filamentation induced by cAMP protein fic
KPPHDEDB_02036 1.5e-168 L Transposase, Mutator family
KPPHDEDB_02037 3.5e-113 L Phage integrase family
KPPHDEDB_02038 8.1e-17
KPPHDEDB_02039 5.8e-47
KPPHDEDB_02040 1.6e-45 K Helix-turn-helix XRE-family like proteins
KPPHDEDB_02041 2.7e-84
KPPHDEDB_02042 4.3e-10 sprF 4.6.1.1 M Cell surface antigen C-terminus
KPPHDEDB_02043 2e-81
KPPHDEDB_02044 2.6e-25 L Transposase, Mutator family
KPPHDEDB_02045 8.6e-11 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KPPHDEDB_02047 3.3e-26
KPPHDEDB_02048 1.3e-142 fic D Fic/DOC family
KPPHDEDB_02049 2.6e-263 L Phage integrase family
KPPHDEDB_02050 5.9e-185 V Abi-like protein
KPPHDEDB_02051 1.9e-15 V Abi-like protein
KPPHDEDB_02052 1.2e-55 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02053 1.2e-16 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02054 1.1e-07 L Transposase, Mutator family
KPPHDEDB_02057 2.8e-38 yxaM EGP Major Facilitator Superfamily
KPPHDEDB_02058 6e-34 S Bacterial protein of unknown function (DUF961)
KPPHDEDB_02059 3e-26 D COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KPPHDEDB_02061 9.3e-154 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02062 1.5e-102 V ATPases associated with a variety of cellular activities
KPPHDEDB_02063 9.9e-171
KPPHDEDB_02064 4e-25 V ABC-2 family transporter protein
KPPHDEDB_02065 1.7e-90 mutF V ABC transporter ATP-binding
KPPHDEDB_02066 4.9e-62 S ABC-2 family transporter protein
KPPHDEDB_02067 1.3e-57 spaG S Lantibiotic protection ABC transporter permease subunit, MutG family
KPPHDEDB_02068 1.3e-89
KPPHDEDB_02069 1.7e-98 T Transcriptional regulatory protein, C terminal
KPPHDEDB_02070 1.1e-117 T PhoQ Sensor
KPPHDEDB_02071 4.3e-88
KPPHDEDB_02072 9.3e-159 EG EamA-like transporter family
KPPHDEDB_02073 2.7e-70 pdxH S Pfam:Pyridox_oxidase
KPPHDEDB_02074 4.8e-238 L ribosomal rna small subunit methyltransferase
KPPHDEDB_02075 1.2e-160 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KPPHDEDB_02076 6.3e-171 corA P CorA-like Mg2+ transporter protein
KPPHDEDB_02077 1.6e-149 ET Bacterial periplasmic substrate-binding proteins
KPPHDEDB_02078 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPPHDEDB_02079 7e-58 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
KPPHDEDB_02080 4.8e-249 comE S Competence protein
KPPHDEDB_02081 1.7e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
KPPHDEDB_02082 1.1e-101 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
KPPHDEDB_02083 6.9e-150 yeaZ 2.3.1.234 O Glycoprotease family
KPPHDEDB_02084 1.7e-96 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
KPPHDEDB_02085 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPPHDEDB_02087 3.7e-11 2.7.11.1 S HipA-like C-terminal domain
KPPHDEDB_02090 5.5e-56 S Fic/DOC family
KPPHDEDB_02091 1.4e-20
KPPHDEDB_02092 1e-172 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02093 1.2e-48 L PFAM Relaxase mobilization nuclease family protein
KPPHDEDB_02094 6.3e-199 V AAA domain, putative AbiEii toxin, Type IV TA system
KPPHDEDB_02095 1.9e-142 S ABC-2 family transporter protein
KPPHDEDB_02096 2e-139
KPPHDEDB_02097 1.7e-58
KPPHDEDB_02099 5.6e-239 T Histidine kinase
KPPHDEDB_02100 1.2e-120 K helix_turn_helix, Lux Regulon
KPPHDEDB_02102 4.1e-103 M Peptidase family M23
KPPHDEDB_02103 1.1e-255 G ABC transporter substrate-binding protein
KPPHDEDB_02104 3.9e-242 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
KPPHDEDB_02105 2.5e-147 guaB 1.1.1.205 F IMP dehydrogenase family protein
KPPHDEDB_02106 5.2e-121
KPPHDEDB_02107 1.2e-46
KPPHDEDB_02108 7.6e-10 L Transposase DDE domain
KPPHDEDB_02111 1.2e-09 S Protein of unknown function (DUF2815)
KPPHDEDB_02112 2.7e-225 lacS G Psort location CytoplasmicMembrane, score 10.00
KPPHDEDB_02113 5.6e-270 lacS G Psort location CytoplasmicMembrane, score 10.00
KPPHDEDB_02114 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KPPHDEDB_02115 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
KPPHDEDB_02116 5.6e-256 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
KPPHDEDB_02117 4.2e-69 fucU 5.1.3.29 G RbsD / FucU transport protein family
KPPHDEDB_02118 1.4e-151 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KPPHDEDB_02119 3.9e-142 IQ KR domain
KPPHDEDB_02120 1.8e-242 4.2.1.68 M Enolase C-terminal domain-like
KPPHDEDB_02121 1.3e-95 S Protein of unknown function, DUF624
KPPHDEDB_02122 2e-112 L PFAM Integrase catalytic
KPPHDEDB_02123 1.8e-89 S Domain of unknown function (DUF4143)
KPPHDEDB_02124 9.5e-239 yhjX EGP Major facilitator Superfamily
KPPHDEDB_02125 0.0 trxB1 1.8.1.9 C Thioredoxin domain
KPPHDEDB_02126 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
KPPHDEDB_02127 1.1e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KPPHDEDB_02128 2e-85 V Forkhead associated domain
KPPHDEDB_02129 2.8e-202 S AAA ATPase domain
KPPHDEDB_02130 1e-235 ytfL P Transporter associated domain
KPPHDEDB_02131 3.3e-83 dps P Belongs to the Dps family
KPPHDEDB_02132 8.3e-63 gntK 1.1.1.343, 1.1.1.44, 2.7.1.12, 2.7.1.71 F Shikimate kinase
KPPHDEDB_02133 1.2e-33 K FCD
KPPHDEDB_02134 1.7e-145 S Protein of unknown function DUF45
KPPHDEDB_02137 6.2e-29 L DNA integration
KPPHDEDB_02139 1.3e-34
KPPHDEDB_02140 3.8e-30 tnpA L Transposase
KPPHDEDB_02141 1.9e-48 L PFAM Integrase catalytic
KPPHDEDB_02142 1.3e-28 relB L RelB antitoxin
KPPHDEDB_02143 6.9e-28 S addiction module toxin, RelE StbE family
KPPHDEDB_02144 1.8e-251 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KPPHDEDB_02145 6.8e-15 K helix_turn _helix lactose operon repressor
KPPHDEDB_02146 2.5e-272 S ATPase domain predominantly from Archaea
KPPHDEDB_02147 6.8e-81
KPPHDEDB_02148 6.7e-87
KPPHDEDB_02149 2.8e-287 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
KPPHDEDB_02150 1.5e-149 scrT G Transporter major facilitator family protein
KPPHDEDB_02151 1.6e-215 S Glycosyl transferase family 2
KPPHDEDB_02152 1.1e-70 cps3I G Psort location CytoplasmicMembrane, score 9.99
KPPHDEDB_02153 1.9e-112 L PFAM Integrase catalytic
KPPHDEDB_02154 2.1e-88 L PFAM Integrase catalytic
KPPHDEDB_02156 1.8e-144 gtrB GT2 M Glycosyl transferase family 2
KPPHDEDB_02157 2.7e-113 M 4-amino-4-deoxy-L-arabinose transferase activity
KPPHDEDB_02158 1.9e-21 L IstB-like ATP binding protein
KPPHDEDB_02159 2.4e-128 L IstB-like ATP binding protein
KPPHDEDB_02160 8.9e-145 L PFAM Integrase catalytic
KPPHDEDB_02161 9.4e-87 L PFAM Integrase catalytic
KPPHDEDB_02162 1.3e-14 L IstB-like ATP binding N-terminal
KPPHDEDB_02163 9.8e-25 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_02164 1e-59 L Integrase core domain
KPPHDEDB_02165 6.6e-49 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02166 7.2e-129 2.7.7.7 L Transposase, Mutator family
KPPHDEDB_02171 5.9e-104 S UPF0126 domain
KPPHDEDB_02172 1.4e-47 G Bacterial extracellular solute-binding protein
KPPHDEDB_02180 1.1e-29 3.1.1.53 L Calcineurin-like phosphoesterase
KPPHDEDB_02183 1.4e-23
KPPHDEDB_02190 1.7e-63 M Sortase family
KPPHDEDB_02199 2.8e-87 L Psort location Cytoplasmic, score 8.87
KPPHDEDB_02208 3.7e-19 secG U Preprotein translocase SecG subunit
KPPHDEDB_02210 7.8e-13 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPPHDEDB_02229 7.4e-39 S Bifunctional DNA primase/polymerase, N-terminal
KPPHDEDB_02230 4e-187 K Psort location Cytoplasmic, score
KPPHDEDB_02231 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KPPHDEDB_02232 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
KPPHDEDB_02233 6.1e-134 L Transposase
KPPHDEDB_02234 2.5e-113
KPPHDEDB_02235 7.5e-48
KPPHDEDB_02236 5.6e-112 S AIPR protein
KPPHDEDB_02237 2.6e-105 M domain protein
KPPHDEDB_02238 0.0 1.3.98.1, 3.2.1.21 GH3 M Conserved repeat domain
KPPHDEDB_02239 1e-80
KPPHDEDB_02242 8.9e-26 dexB 2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97 GH101,GH13,GH29,GH31 G hydrolase activity, hydrolyzing O-glycosyl compounds
KPPHDEDB_02243 5e-96 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPPHDEDB_02245 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
KPPHDEDB_02246 1.2e-291 pccB I Carboxyl transferase domain
KPPHDEDB_02247 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KPPHDEDB_02248 1.5e-13 bioY S BioY family
KPPHDEDB_02249 4.5e-142 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KPPHDEDB_02250 0.0
KPPHDEDB_02251 5.4e-137 QT PucR C-terminal helix-turn-helix domain
KPPHDEDB_02252 2.5e-24 K helix_turn _helix lactose operon repressor
KPPHDEDB_02253 7e-117 2.2.1.1 G Transketolase, pyrimidine binding domain
KPPHDEDB_02254 3.2e-108 tktN 2.2.1.1 G Dehydrogenase E1 component
KPPHDEDB_02255 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KPPHDEDB_02256 6.2e-130 EGP Major facilitator Superfamily
KPPHDEDB_02257 2.1e-08 ycnE S Antibiotic biosynthesis monooxygenase
KPPHDEDB_02258 1.9e-115 iolT EGP Major facilitator Superfamily
KPPHDEDB_02259 1.2e-128 iolE 4.2.1.44 G dehydratase
KPPHDEDB_02260 4e-139 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KPPHDEDB_02261 4.9e-105 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KPPHDEDB_02262 2.5e-48 K helix_turn_helix, arabinose operon control protein
KPPHDEDB_02263 1.5e-157 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KPPHDEDB_02264 1.3e-83 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KPPHDEDB_02265 5.2e-75 K Sugar-specific transcriptional regulator TrmB
KPPHDEDB_02266 8e-68 K Bacterial transcriptional regulator
KPPHDEDB_02267 7.1e-206 1.2.1.16, 1.2.1.20, 1.2.1.79 C Aldehyde dehydrogenase family
KPPHDEDB_02268 2.4e-161 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
KPPHDEDB_02269 1.9e-129 iolB 5.3.1.30 G PFAM Myo-inositol catabolism IolB domain protein
KPPHDEDB_02270 1.4e-275 iolD 3.7.1.22 E Thiamine pyrophosphate enzyme, central domain
KPPHDEDB_02271 5.2e-29 insK L Integrase core domain
KPPHDEDB_02272 4.3e-146 cobB2 K Sir2 family
KPPHDEDB_02273 4.5e-233 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KPPHDEDB_02274 1.1e-209 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KPPHDEDB_02275 2.4e-65 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KPPHDEDB_02276 4e-111 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KPPHDEDB_02277 2.4e-81 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPPHDEDB_02278 0.0 yjcE P Sodium/hydrogen exchanger family
KPPHDEDB_02279 1.5e-146 ypfH S Phospholipase/Carboxylesterase
KPPHDEDB_02280 9.3e-129
KPPHDEDB_02281 3.4e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
KPPHDEDB_02282 3e-85
KPPHDEDB_02283 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KPPHDEDB_02284 2e-16 K helix_turn _helix lactose operon repressor
KPPHDEDB_02285 7.8e-83 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPPHDEDB_02286 2.5e-286 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
KPPHDEDB_02287 4.7e-203 EGP Major facilitator Superfamily
KPPHDEDB_02288 7.5e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPPHDEDB_02289 1.1e-267 KLT Domain of unknown function (DUF4032)
KPPHDEDB_02290 1.8e-209 ugpC E Belongs to the ABC transporter superfamily
KPPHDEDB_02291 5.9e-219 2.4.1.166 GT2 M Glycosyltransferase like family 2
KPPHDEDB_02292 8.2e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPPHDEDB_02294 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPPHDEDB_02295 6.5e-81 nrdI F Probably involved in ribonucleotide reductase function
KPPHDEDB_02296 4.1e-43 nrdH O Glutaredoxin
KPPHDEDB_02297 4.6e-273 KLT Protein tyrosine kinase
KPPHDEDB_02298 1.6e-121 O Thioredoxin
KPPHDEDB_02300 1.2e-211 S G5
KPPHDEDB_02301 8.5e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPPHDEDB_02302 4.2e-175 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KPPHDEDB_02303 1.2e-106 S LytR cell envelope-related transcriptional attenuator
KPPHDEDB_02304 8.2e-276 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
KPPHDEDB_02305 1.6e-116 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
KPPHDEDB_02306 0.0
KPPHDEDB_02307 0.0 murJ KLT MviN-like protein
KPPHDEDB_02308 1.7e-185 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPPHDEDB_02309 6.4e-217 parB K Belongs to the ParB family
KPPHDEDB_02310 7.8e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
KPPHDEDB_02311 1.4e-121 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KPPHDEDB_02312 2.5e-92 jag S Putative single-stranded nucleic acids-binding domain
KPPHDEDB_02313 1.7e-174 yidC U Membrane protein insertase, YidC Oxa1 family
KPPHDEDB_02314 4e-33 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPPHDEDB_02315 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KPPHDEDB_02316 4.6e-285 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPPHDEDB_02317 8.4e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPPHDEDB_02318 8.3e-224 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPPHDEDB_02319 8.7e-81 S Protein of unknown function (DUF721)
KPPHDEDB_02320 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPPHDEDB_02321 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPPHDEDB_02322 2.1e-81 S Transmembrane domain of unknown function (DUF3566)
KPPHDEDB_02323 1.6e-23 2.7.7.7 L Transposase, Mutator family
KPPHDEDB_02325 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KPPHDEDB_02326 3.2e-22 araE EGP Major facilitator Superfamily
KPPHDEDB_02327 1.5e-61 cydD V ABC transporter transmembrane region
KPPHDEDB_02328 1.2e-12 cydD V ABC transporter transmembrane region
KPPHDEDB_02329 5.9e-117 cydD V ABC transporter transmembrane region
KPPHDEDB_02330 6.7e-248 araE EGP Major facilitator Superfamily
KPPHDEDB_02331 9.1e-101 2.7.13.3 T Histidine kinase
KPPHDEDB_02332 4.3e-41 K helix_turn_helix, Lux Regulon
KPPHDEDB_02333 2.2e-19 S Bacteriocin (Lactococcin_972)
KPPHDEDB_02334 5.7e-243 XK27_10205
KPPHDEDB_02335 4.7e-101 V ABC transporter
KPPHDEDB_02336 1.1e-26
KPPHDEDB_02337 1.4e-26 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KPPHDEDB_02339 9.6e-171 K helix_turn _helix lactose operon repressor
KPPHDEDB_02340 4.1e-15 tnp3512a L Transposase
KPPHDEDB_02342 7.7e-51 tnp7109-2 L Transposase, Mutator family
KPPHDEDB_02343 9.5e-92 tnp7109-2 L Transposase, Mutator family
KPPHDEDB_02344 1.2e-91 K helix_turn_helix, Lux Regulon
KPPHDEDB_02345 7.8e-163 T Histidine kinase
KPPHDEDB_02346 7.9e-119 V ABC transporter, ATP-binding protein
KPPHDEDB_02347 0.0 V ABC transporter, ATP-binding protein
KPPHDEDB_02348 2.2e-120 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
KPPHDEDB_02349 2.6e-135 L Protein of unknown function (DUF1524)
KPPHDEDB_02350 9.5e-205 mntH P H( )-stimulated, divalent metal cation uptake system
KPPHDEDB_02351 1.9e-260 EGP Major facilitator Superfamily
KPPHDEDB_02352 2.6e-24 S AAA ATPase domain
KPPHDEDB_02353 6.1e-78 S AAA ATPase domain
KPPHDEDB_02354 1.5e-153 S Psort location Cytoplasmic, score 7.50
KPPHDEDB_02355 4.4e-44 V efflux transmembrane transporter activity
KPPHDEDB_02356 2.9e-156 L Transposase and inactivated derivatives IS30 family
KPPHDEDB_02357 8.5e-85 L Phage integrase family
KPPHDEDB_02358 7.3e-22
KPPHDEDB_02359 2.2e-12 L Phage integrase family
KPPHDEDB_02361 1.2e-20
KPPHDEDB_02364 9.7e-201 EGP Major Facilitator Superfamily
KPPHDEDB_02365 3.9e-199 2.7.13.3 T Histidine kinase
KPPHDEDB_02366 8.4e-107 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPPHDEDB_02367 4e-130 V ABC transporter
KPPHDEDB_02368 3.8e-117
KPPHDEDB_02369 4.1e-39 L Transposase
KPPHDEDB_02371 8.6e-70 rplI J Binds to the 23S rRNA
KPPHDEDB_02372 2.6e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPPHDEDB_02373 3.9e-71 ssb1 L Single-stranded DNA-binding protein
KPPHDEDB_02374 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KPPHDEDB_02375 2.6e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPPHDEDB_02376 3e-132 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPPHDEDB_02377 0.0 ubiB S ABC1 family
KPPHDEDB_02378 1e-31 S granule-associated protein
KPPHDEDB_02379 3.7e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KPPHDEDB_02380 9.6e-259 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
KPPHDEDB_02381 8.5e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KPPHDEDB_02382 3e-249 dinF V MatE
KPPHDEDB_02383 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KPPHDEDB_02384 1e-54 glnB K Nitrogen regulatory protein P-II
KPPHDEDB_02385 6.9e-229 amt U Ammonium Transporter Family
KPPHDEDB_02386 9.2e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPPHDEDB_02387 4.6e-17
KPPHDEDB_02388 2.4e-44 S Protein of unknown function (DUF2089)
KPPHDEDB_02389 1.3e-123 icaR K Bacterial regulatory proteins, tetR family
KPPHDEDB_02390 3.1e-187 XK27_01805 M Glycosyltransferase like family 2
KPPHDEDB_02391 9.5e-265 pepD E Peptidase family C69
KPPHDEDB_02392 1.8e-07
KPPHDEDB_02393 9e-40
KPPHDEDB_02395 1.8e-300 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPPHDEDB_02396 1.6e-183 opcA G Glucose-6-phosphate dehydrogenase subunit
KPPHDEDB_02397 9.6e-131 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KPPHDEDB_02398 5.5e-267 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPPHDEDB_02399 1.5e-231 S Putative ABC-transporter type IV
KPPHDEDB_02400 0.0 pip S YhgE Pip domain protein
KPPHDEDB_02401 1.6e-307 pip S YhgE Pip domain protein
KPPHDEDB_02402 5.4e-104 K Psort location Cytoplasmic, score 8.87
KPPHDEDB_02403 2.8e-65 S FMN_bind
KPPHDEDB_02404 2.6e-146 macB V ABC transporter, ATP-binding protein
KPPHDEDB_02405 9.1e-215 Z012_06715 V FtsX-like permease family
KPPHDEDB_02406 2.2e-214 macB_2 V ABC transporter permease
KPPHDEDB_02407 5e-232 S Predicted membrane protein (DUF2318)
KPPHDEDB_02408 3.6e-107 tpd P Fe2+ transport protein
KPPHDEDB_02409 0.0 efeU_1 P Iron permease FTR1 family
KPPHDEDB_02410 6.1e-299
KPPHDEDB_02412 8.5e-96 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KPPHDEDB_02413 2.2e-135 yoaK S Protein of unknown function (DUF1275)
KPPHDEDB_02414 1.3e-66
KPPHDEDB_02417 4.7e-293 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPPHDEDB_02418 8.2e-143 S Protein of unknown function (DUF805)
KPPHDEDB_02419 2e-163 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KPPHDEDB_02420 9e-159
KPPHDEDB_02421 1.7e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
KPPHDEDB_02422 5e-260 EGP Major facilitator Superfamily
KPPHDEDB_02423 1.5e-110 rnr 3.6.4.12 K Putative DNA-binding domain
KPPHDEDB_02424 2.4e-95 S GtrA-like protein
KPPHDEDB_02425 8.7e-62 S Macrophage migration inhibitory factor (MIF)
KPPHDEDB_02426 2.6e-291 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
KPPHDEDB_02427 2.2e-311 pepD E Peptidase family C69
KPPHDEDB_02428 2.1e-105 S Phosphatidylethanolamine-binding protein
KPPHDEDB_02429 1.1e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPPHDEDB_02431 3.3e-37 ptsH G PTS HPr component phosphorylation site
KPPHDEDB_02432 5e-100 K helix_turn _helix lactose operon repressor
KPPHDEDB_02433 9.9e-203 holB 2.7.7.7 L DNA polymerase III
KPPHDEDB_02434 4e-122 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPPHDEDB_02435 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPPHDEDB_02436 2e-156 3.6.1.27 I PAP2 superfamily
KPPHDEDB_02437 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KPPHDEDB_02438 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPPHDEDB_02439 7.4e-310 S Calcineurin-like phosphoesterase
KPPHDEDB_02440 1.1e-115
KPPHDEDB_02441 6.7e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPPHDEDB_02442 8e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
KPPHDEDB_02443 2.3e-131 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KPPHDEDB_02444 2.8e-53 S Psort location Cytoplasmic, score
KPPHDEDB_02445 2.4e-201 3.4.22.70 M Sortase family
KPPHDEDB_02446 2.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPPHDEDB_02447 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
KPPHDEDB_02448 4.1e-99 K Bacterial regulatory proteins, tetR family
KPPHDEDB_02449 7.6e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
KPPHDEDB_02450 1.5e-53 S TIGRFAM helicase secretion neighborhood TadE-like protein
KPPHDEDB_02451 4.6e-40 S Protein of unknown function (DUF4244)
KPPHDEDB_02452 4.8e-100 gspF NU Type II secretion system (T2SS), protein F
KPPHDEDB_02453 8.3e-106 U Type ii secretion system
KPPHDEDB_02454 8e-191 cpaF U Type II IV secretion system protein
KPPHDEDB_02455 1e-93 cpaE D bacterial-type flagellum organization
KPPHDEDB_02456 6.1e-134 dedA S SNARE associated Golgi protein
KPPHDEDB_02457 5.3e-124 S HAD hydrolase, family IA, variant 3
KPPHDEDB_02458 3.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KPPHDEDB_02459 3.2e-230 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
KPPHDEDB_02460 4.2e-206 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
KPPHDEDB_02461 1e-214 F Psort location CytoplasmicMembrane, score 10.00
KPPHDEDB_02462 4e-99 hspR K transcriptional regulator, MerR family
KPPHDEDB_02463 9.7e-170 dnaJ1 O DnaJ molecular chaperone homology domain
KPPHDEDB_02464 7e-55 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPPHDEDB_02465 0.0 dnaK O Heat shock 70 kDa protein
KPPHDEDB_02466 1.8e-237 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPPHDEDB_02467 8.1e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPPHDEDB_02468 4.5e-211 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPPHDEDB_02469 4e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
KPPHDEDB_02470 2.8e-277 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPPHDEDB_02471 3.9e-92
KPPHDEDB_02473 1.5e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPPHDEDB_02474 2.7e-140 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPPHDEDB_02476 3e-277 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPPHDEDB_02477 1.7e-67 K Transcriptional regulator
KPPHDEDB_02478 2.1e-194 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KPPHDEDB_02479 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KPPHDEDB_02480 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
KPPHDEDB_02481 6.1e-160 arbG K CAT RNA binding domain
KPPHDEDB_02482 1.7e-202 I Diacylglycerol kinase catalytic domain
KPPHDEDB_02483 9.5e-239 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPPHDEDB_02485 7.5e-247 G Bacterial extracellular solute-binding protein
KPPHDEDB_02486 1.9e-170 malC G Binding-protein-dependent transport system inner membrane component
KPPHDEDB_02487 1.6e-150 G ABC transporter permease
KPPHDEDB_02488 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KPPHDEDB_02489 2.1e-191 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
KPPHDEDB_02490 5.6e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KPPHDEDB_02491 1.7e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPPHDEDB_02492 2.7e-110 degU K helix_turn_helix, Lux Regulon
KPPHDEDB_02493 8.4e-224 tcsS3 KT PspC domain
KPPHDEDB_02494 2.7e-167 pspC KT PspC domain
KPPHDEDB_02495 1.3e-53
KPPHDEDB_02496 7.1e-284 S alpha beta
KPPHDEDB_02497 1.2e-112 S Protein of unknown function (DUF4125)
KPPHDEDB_02498 4.7e-280 S Domain of unknown function (DUF4037)
KPPHDEDB_02499 0.0 phoC 3.1.3.5 I PAP2 superfamily
KPPHDEDB_02500 9.8e-206 araJ EGP Major facilitator Superfamily
KPPHDEDB_02502 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KPPHDEDB_02503 2.3e-128 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KPPHDEDB_02504 2.7e-54 yxaM EGP Major facilitator Superfamily
KPPHDEDB_02505 1e-54 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
KPPHDEDB_02506 8.6e-19 pin L Resolvase, N terminal domain
KPPHDEDB_02507 1.4e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPPHDEDB_02508 1.7e-114 phoU P Plays a role in the regulation of phosphate uptake
KPPHDEDB_02509 2.3e-194 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KPPHDEDB_02510 4.3e-37
KPPHDEDB_02511 3.4e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPPHDEDB_02513 6.1e-166 usp 3.5.1.28 CBM50 S CHAP domain
KPPHDEDB_02514 3.4e-95 M NlpC/P60 family
KPPHDEDB_02515 5.7e-103 M NlpC/P60 family
KPPHDEDB_02516 8.9e-187 T Universal stress protein family
KPPHDEDB_02517 1.2e-73 attW O OsmC-like protein
KPPHDEDB_02518 3.6e-173 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPPHDEDB_02520 2e-123 folA 1.5.1.3 H dihydrofolate reductase
KPPHDEDB_02521 1.1e-97 ptpA 3.1.3.48 T low molecular weight

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)