ORF_ID e_value Gene_name EC_number CAZy COGs Description
MLLIABJA_00001 7.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
MLLIABJA_00002 7.4e-43
MLLIABJA_00003 7.5e-51
MLLIABJA_00004 1.7e-265 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLLIABJA_00005 8.7e-156 aatB ET ABC transporter substrate-binding protein
MLLIABJA_00006 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_00007 1.4e-105 artQ P ABC transporter (Permease
MLLIABJA_00008 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
MLLIABJA_00009 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLLIABJA_00010 2.9e-165 cpsY K Transcriptional regulator
MLLIABJA_00011 6e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
MLLIABJA_00012 6e-164 yeiH S Membrane
MLLIABJA_00014 2.6e-09
MLLIABJA_00015 2e-283 adcA P Belongs to the bacterial solute-binding protein 9 family
MLLIABJA_00016 1e-145 XK27_10720 D peptidase activity
MLLIABJA_00017 1.1e-277 pepD E Dipeptidase
MLLIABJA_00018 2.2e-160 whiA K May be required for sporulation
MLLIABJA_00019 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MLLIABJA_00020 6.5e-162 rapZ S Displays ATPase and GTPase activities
MLLIABJA_00021 2.6e-135 yejC S cyclic nucleotide-binding protein
MLLIABJA_00022 2.2e-205 D nuclear chromosome segregation
MLLIABJA_00023 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MLLIABJA_00024 1.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLLIABJA_00025 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MLLIABJA_00026 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLLIABJA_00027 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MLLIABJA_00028 3.7e-19
MLLIABJA_00029 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MLLIABJA_00030 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MLLIABJA_00031 1.2e-80 ypmB S Protein conserved in bacteria
MLLIABJA_00032 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MLLIABJA_00033 2.3e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MLLIABJA_00034 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
MLLIABJA_00035 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
MLLIABJA_00036 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MLLIABJA_00037 3.2e-187 tcsA S membrane
MLLIABJA_00038 1.5e-65 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLLIABJA_00039 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLLIABJA_00040 1.6e-230 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MLLIABJA_00041 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
MLLIABJA_00042 2.8e-171 coaA 2.7.1.33 F Pantothenic acid kinase
MLLIABJA_00043 1e-29 rpsT J Binds directly to 16S ribosomal RNA
MLLIABJA_00044 1.3e-241 T PhoQ Sensor
MLLIABJA_00045 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLLIABJA_00046 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MLLIABJA_00047 1.9e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MLLIABJA_00048 2.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLLIABJA_00049 1.7e-91 panT S ECF transporter, substrate-specific component
MLLIABJA_00050 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MLLIABJA_00051 1.6e-165 metF 1.5.1.20 E reductase
MLLIABJA_00052 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLLIABJA_00054 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MLLIABJA_00055 0.0 3.6.3.8 P cation transport ATPase
MLLIABJA_00056 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLLIABJA_00057 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLLIABJA_00058 5.6e-236 dltB M Membrane protein involved in D-alanine export
MLLIABJA_00059 1.5e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLLIABJA_00060 0.0 XK27_10035 V abc transporter atp-binding protein
MLLIABJA_00061 1.5e-290 yfiB1 V abc transporter atp-binding protein
MLLIABJA_00062 1.4e-99 pvaA M lytic transglycosylase activity
MLLIABJA_00063 2.1e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MLLIABJA_00064 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLLIABJA_00065 4.5e-106 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLLIABJA_00066 8.3e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLLIABJA_00067 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLLIABJA_00068 5.1e-110 tdk 2.7.1.21 F thymidine kinase
MLLIABJA_00069 5.8e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MLLIABJA_00070 8.4e-153 gst O Glutathione S-transferase
MLLIABJA_00071 1.7e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MLLIABJA_00072 1.7e-168 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MLLIABJA_00073 4.4e-45 rpmE2 J 50S ribosomal protein L31
MLLIABJA_00074 9.7e-203 mntH P Mn2 and Fe2 transporters of the NRAMP family
MLLIABJA_00075 2.7e-16 mntH P Mn2 and Fe2 transporters of the NRAMP family
MLLIABJA_00076 8.4e-163 ypuA S secreted protein
MLLIABJA_00077 2e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
MLLIABJA_00078 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MLLIABJA_00079 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLLIABJA_00080 3.8e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MLLIABJA_00081 1.9e-88 L COG1943 Transposase and inactivated derivatives
MLLIABJA_00082 3.9e-254 noxE P NADH oxidase
MLLIABJA_00083 2.5e-294 yfmM S abc transporter atp-binding protein
MLLIABJA_00084 7.5e-81 XK27_01265 S ECF-type riboflavin transporter, S component
MLLIABJA_00085 1.1e-134 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MLLIABJA_00086 9.4e-81 S ECF-type riboflavin transporter, S component
MLLIABJA_00088 1.3e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLLIABJA_00089 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MLLIABJA_00091 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLLIABJA_00092 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLLIABJA_00093 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLLIABJA_00094 3.8e-22 WQ51_00220 K Helix-turn-helix domain
MLLIABJA_00095 9.1e-90 S Protein of unknown function (DUF3278)
MLLIABJA_00096 0.0 smc D Required for chromosome condensation and partitioning
MLLIABJA_00097 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLLIABJA_00098 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLLIABJA_00099 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLLIABJA_00100 5.4e-121 alkD L DNA alkylation repair enzyme
MLLIABJA_00101 5.7e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLLIABJA_00102 5.2e-87 pat 2.3.1.183 M acetyltransferase
MLLIABJA_00103 2.6e-269 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLLIABJA_00104 2.6e-152 L PFAM Integrase catalytic region
MLLIABJA_00105 3.5e-29 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLLIABJA_00106 4.9e-227 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLLIABJA_00107 1.2e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MLLIABJA_00108 1.5e-36 L RePlication protein
MLLIABJA_00109 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLLIABJA_00110 4.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MLLIABJA_00111 5.7e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MLLIABJA_00112 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
MLLIABJA_00113 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
MLLIABJA_00114 6.7e-162 yjlA EG membrane
MLLIABJA_00115 1.3e-80 3.4.21.89 S RDD family
MLLIABJA_00116 7.5e-49
MLLIABJA_00117 1.7e-88
MLLIABJA_00118 2.3e-24
MLLIABJA_00119 2.2e-76 K Acetyltransferase (GNAT) domain
MLLIABJA_00120 5.1e-142 S ABC-2 family transporter protein
MLLIABJA_00121 2.4e-142 S ABC-2 family transporter protein
MLLIABJA_00122 3e-184 S AAA domain, putative AbiEii toxin, Type IV TA system
MLLIABJA_00125 9.5e-85 yfjR K regulation of single-species biofilm formation
MLLIABJA_00126 1e-125 S Protein of unknown function DUF262
MLLIABJA_00127 3.2e-201 S Protein of unknown function DUF262
MLLIABJA_00128 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLLIABJA_00129 3.6e-186 desK 2.7.13.3 T Histidine kinase
MLLIABJA_00130 1.2e-132 yvfS V ABC-2 type transporter
MLLIABJA_00131 6.7e-159 XK27_09825 V 'abc transporter, ATP-binding protein
MLLIABJA_00135 1.8e-195 anK3 G response to abiotic stimulus
MLLIABJA_00136 0.0 hscC O Belongs to the heat shock protein 70 family
MLLIABJA_00137 2.5e-153 yocS S Transporter
MLLIABJA_00138 1.1e-68 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
MLLIABJA_00139 1.2e-116 yvfS V Transporter
MLLIABJA_00140 3.4e-155 XK27_09825 V abc transporter atp-binding protein
MLLIABJA_00141 4.1e-15 liaI KT membrane
MLLIABJA_00142 4.4e-30 liaI KT membrane
MLLIABJA_00143 6.1e-93 XK27_05000 S metal cluster binding
MLLIABJA_00144 0.0 V ABC transporter (permease)
MLLIABJA_00145 7.8e-132 macB2 V ABC transporter, ATP-binding protein
MLLIABJA_00146 4.9e-163 T Histidine kinase
MLLIABJA_00147 2.7e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLLIABJA_00148 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLLIABJA_00149 2.5e-223 pbuX F xanthine permease
MLLIABJA_00150 6.7e-274 V (ABC) transporter
MLLIABJA_00151 4.9e-143 K sequence-specific DNA binding
MLLIABJA_00152 3.4e-231 norM V Multidrug efflux pump
MLLIABJA_00154 3e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLLIABJA_00155 3.4e-231 brnQ E Component of the transport system for branched-chain amino acids
MLLIABJA_00156 2.1e-179 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLLIABJA_00157 3.5e-55 S Protein of unknown function (DUF3290)
MLLIABJA_00158 1.1e-107 S Protein of unknown function (DUF421)
MLLIABJA_00159 4.6e-15 csbD K CsbD-like
MLLIABJA_00160 1.2e-108 S Carbohydrate-binding domain-containing protein Cthe_2159
MLLIABJA_00161 7.4e-37 XK27_01300 S ASCH
MLLIABJA_00162 7.9e-215 yfnA E amino acid
MLLIABJA_00163 0.0 S dextransucrase activity
MLLIABJA_00165 6.2e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_00166 2.1e-112 yxeN P ABC transporter, permease protein
MLLIABJA_00167 2.9e-109 ytmL P ABC transporter (Permease
MLLIABJA_00168 1.2e-163 ET ABC transporter substrate-binding protein
MLLIABJA_00169 4e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
MLLIABJA_00170 3.9e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MLLIABJA_00171 1.5e-42 S Sugar efflux transporter for intercellular exchange
MLLIABJA_00172 1.3e-202 P FtsX-like permease family
MLLIABJA_00173 1.5e-121 V abc transporter atp-binding protein
MLLIABJA_00174 9.6e-98 K WHG domain
MLLIABJA_00175 2.6e-169 ydhF S Aldo keto reductase
MLLIABJA_00176 4.1e-107 XK27_02070 S nitroreductase
MLLIABJA_00177 4.2e-150 1.13.11.2 S glyoxalase
MLLIABJA_00178 7.2e-74 ywnA K Transcriptional regulator
MLLIABJA_00179 2e-155 E Alpha/beta hydrolase of unknown function (DUF915)
MLLIABJA_00180 3.7e-222 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLLIABJA_00181 6.3e-168 bcrA V abc transporter atp-binding protein
MLLIABJA_00182 1.2e-127 S ABC-2 family transporter protein
MLLIABJA_00183 1.3e-130 T PhoQ Sensor
MLLIABJA_00184 8.4e-125 T Xre family transcriptional regulator
MLLIABJA_00185 3.5e-109 drgA C nitroreductase
MLLIABJA_00186 1.4e-103 yoaK S Protein of unknown function (DUF1275)
MLLIABJA_00187 9.9e-39 DJ nuclease activity
MLLIABJA_00188 1.9e-30 XK27_10490
MLLIABJA_00189 1e-156 yvgN C reductase
MLLIABJA_00190 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLLIABJA_00191 1.1e-243 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MLLIABJA_00192 1.8e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLLIABJA_00193 5.1e-150 galR K Transcriptional regulator
MLLIABJA_00194 4.2e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
MLLIABJA_00195 2.9e-227 vncS 2.7.13.3 T Histidine kinase
MLLIABJA_00196 1.5e-115 K Response regulator receiver domain protein
MLLIABJA_00197 7.6e-234 vex3 V Efflux ABC transporter, permease protein
MLLIABJA_00198 4.3e-107 vex2 V abc transporter atp-binding protein
MLLIABJA_00199 4e-181 vex1 V Efflux ABC transporter, permease protein
MLLIABJA_00200 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
MLLIABJA_00202 4.8e-199 gldA 1.1.1.6 C glycerol dehydrogenase
MLLIABJA_00203 4.2e-178 XK27_10475 S oxidoreductase
MLLIABJA_00204 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
MLLIABJA_00205 1.5e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
MLLIABJA_00206 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
MLLIABJA_00207 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
MLLIABJA_00208 0.0 M Putative cell wall binding repeat
MLLIABJA_00209 9.3e-34 S Immunity protein 41
MLLIABJA_00210 0.0 pepO 3.4.24.71 O Peptidase family M13
MLLIABJA_00211 3.4e-07 S Enterocin A Immunity
MLLIABJA_00212 3.9e-14 S integral membrane protein
MLLIABJA_00213 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
MLLIABJA_00214 2.2e-107 yhfC S Putative membrane peptidase family (DUF2324)
MLLIABJA_00215 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00217 7.3e-254 S dextransucrase activity
MLLIABJA_00218 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00219 9.1e-36 M Putative cell wall binding repeat
MLLIABJA_00220 1.2e-22 S dextransucrase activity
MLLIABJA_00221 8.9e-238 M Putative cell wall binding repeat
MLLIABJA_00222 9.9e-229 S dextransucrase activity
MLLIABJA_00223 3.1e-92 S dextransucrase activity
MLLIABJA_00224 0.0 S dextransucrase activity
MLLIABJA_00225 5.5e-63
MLLIABJA_00226 3.1e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLLIABJA_00227 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLLIABJA_00228 8.1e-290 S dextransucrase activity
MLLIABJA_00229 2e-173 S dextransucrase activity
MLLIABJA_00230 0.0 S dextransucrase activity
MLLIABJA_00231 4.6e-100 M Putative cell wall binding repeat
MLLIABJA_00232 1.2e-102 S dextransucrase activity
MLLIABJA_00233 2e-83 M Putative cell wall binding repeat
MLLIABJA_00234 7.4e-227 S dextransucrase activity
MLLIABJA_00236 4.3e-130 XK27_00785 S CAAX protease self-immunity
MLLIABJA_00237 1.3e-236 EGP Major facilitator Superfamily
MLLIABJA_00238 6.9e-66 rmaI K Transcriptional regulator, MarR family
MLLIABJA_00239 5.1e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
MLLIABJA_00240 1.4e-133 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
MLLIABJA_00241 0.0 3.5.1.28 M domain protein
MLLIABJA_00242 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00243 8.3e-25
MLLIABJA_00248 0.0 sraP UW Hep Hag repeat protein
MLLIABJA_00249 5.6e-186 nss M transferase activity, transferring glycosyl groups
MLLIABJA_00250 3.6e-16 S Accessory secretory protein Sec, Asp5
MLLIABJA_00251 2.6e-17 S Accessory secretory protein Sec Asp4
MLLIABJA_00252 2.3e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MLLIABJA_00253 2e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MLLIABJA_00254 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLLIABJA_00255 1e-78 asp3 S Accessory Sec system protein Asp3
MLLIABJA_00256 3.7e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
MLLIABJA_00257 2.1e-288 asp1 S Accessory Sec system protein Asp1
MLLIABJA_00258 2e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MLLIABJA_00259 0.0 M family 8
MLLIABJA_00260 0.0 sbcC L ATPase involved in DNA repair
MLLIABJA_00261 5.5e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLLIABJA_00262 0.0 GM domain, Protein
MLLIABJA_00263 0.0 zmpB M signal peptide protein, YSIRK family
MLLIABJA_00264 1.2e-219 L transposase IS116 IS110 IS902 family
MLLIABJA_00265 6.4e-191 L Transposase
MLLIABJA_00266 4.8e-27 bipA S protein secretion
MLLIABJA_00267 2.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLLIABJA_00268 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLLIABJA_00269 2.2e-34 nrdH O Glutaredoxin
MLLIABJA_00270 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLLIABJA_00271 7.4e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
MLLIABJA_00272 1.1e-220 icd 1.1.1.42 C Isocitrate dehydrogenase
MLLIABJA_00273 3e-38 ptsH G phosphocarrier protein Hpr
MLLIABJA_00274 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLLIABJA_00275 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MLLIABJA_00276 7.4e-160 XK27_05670 S Putative esterase
MLLIABJA_00277 3e-152 XK27_05675 S Esterase
MLLIABJA_00278 1.6e-224 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
MLLIABJA_00279 6.3e-175 yfmL 3.6.4.13 L DEAD DEAH box helicase
MLLIABJA_00280 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MLLIABJA_00281 0.0 uup S abc transporter atp-binding protein
MLLIABJA_00282 1.6e-39 MA20_06245 S yiaA/B two helix domain
MLLIABJA_00283 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
MLLIABJA_00284 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLLIABJA_00285 4.8e-148 cobQ S glutamine amidotransferase
MLLIABJA_00286 2.6e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MLLIABJA_00287 6.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLLIABJA_00288 4.6e-161 ybbR S Protein conserved in bacteria
MLLIABJA_00289 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLLIABJA_00290 1.3e-64 gtrA S GtrA-like protein
MLLIABJA_00291 4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
MLLIABJA_00292 1.3e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLLIABJA_00293 2e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
MLLIABJA_00294 1.8e-201 yurR 1.4.5.1 E oxidoreductase
MLLIABJA_00295 1e-259 S phospholipase Carboxylesterase
MLLIABJA_00296 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLLIABJA_00297 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MLLIABJA_00298 1.6e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLLIABJA_00300 2.2e-30 KT response to antibiotic
MLLIABJA_00301 5.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
MLLIABJA_00302 1e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
MLLIABJA_00303 6.1e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLLIABJA_00304 3.2e-118 ylfI S tigr01906
MLLIABJA_00305 1e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MLLIABJA_00306 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MLLIABJA_00307 5.1e-58 XK27_08085
MLLIABJA_00308 6.2e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLLIABJA_00309 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLLIABJA_00310 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLLIABJA_00311 1.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLLIABJA_00312 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MLLIABJA_00313 3.7e-108 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLLIABJA_00314 1.2e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLLIABJA_00315 1.4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLLIABJA_00316 1.7e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MLLIABJA_00317 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MLLIABJA_00319 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
MLLIABJA_00320 3.7e-145 P molecular chaperone
MLLIABJA_00321 4.7e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
MLLIABJA_00322 4.5e-175 XK27_08075 M glycosyl transferase family 2
MLLIABJA_00323 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00324 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00325 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MLLIABJA_00326 2.4e-235 rodA D Belongs to the SEDS family
MLLIABJA_00327 1.2e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLLIABJA_00328 2.6e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MLLIABJA_00329 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLLIABJA_00330 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLLIABJA_00331 2.6e-21 Q Methyltransferase domain
MLLIABJA_00332 8.3e-64 GnaT 2.5.1.16 K acetyltransferase
MLLIABJA_00333 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MLLIABJA_00334 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLLIABJA_00335 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLLIABJA_00336 1.3e-125 dnaD
MLLIABJA_00337 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLLIABJA_00339 3.9e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLLIABJA_00340 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLLIABJA_00341 2.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLLIABJA_00342 3.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MLLIABJA_00343 7e-72 argR K Regulates arginine biosynthesis genes
MLLIABJA_00344 8.7e-301 recN L May be involved in recombinational repair of damaged DNA
MLLIABJA_00345 6.8e-145 DegV S DegV family
MLLIABJA_00346 6.9e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
MLLIABJA_00347 5.2e-96 ypmS S Protein conserved in bacteria
MLLIABJA_00348 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLLIABJA_00350 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MLLIABJA_00351 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLLIABJA_00352 5.5e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLLIABJA_00353 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLLIABJA_00354 2.1e-37 ysdA L Membrane
MLLIABJA_00355 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLLIABJA_00356 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLLIABJA_00357 0.0 dnaE 2.7.7.7 L DNA polymerase
MLLIABJA_00358 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLLIABJA_00359 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MLLIABJA_00360 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
MLLIABJA_00361 1.7e-18 S Domain of unknown function (DUF4649)
MLLIABJA_00362 4e-176 XK27_08835 S ABC transporter substrate binding protein
MLLIABJA_00363 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MLLIABJA_00364 3.1e-136 XK27_08845 S abc transporter atp-binding protein
MLLIABJA_00365 4.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLLIABJA_00366 1.9e-149 estA CE1 S Esterase
MLLIABJA_00367 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MLLIABJA_00368 1.1e-17 XK27_08880
MLLIABJA_00369 1e-75 fld C Flavodoxin
MLLIABJA_00370 7.8e-280 clcA P Chloride transporter, ClC family
MLLIABJA_00371 4.2e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MLLIABJA_00372 1.7e-216 XK27_05110 P Chloride transporter ClC family
MLLIABJA_00373 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLLIABJA_00376 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
MLLIABJA_00377 4.8e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLLIABJA_00378 1.8e-84 ytsP 1.8.4.14 T GAF domain-containing protein
MLLIABJA_00379 1e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLLIABJA_00380 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLLIABJA_00381 7.8e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLLIABJA_00382 8.7e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
MLLIABJA_00383 1.1e-143
MLLIABJA_00384 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MLLIABJA_00385 3.8e-273 pelF GT4 M Domain of unknown function (DUF3492)
MLLIABJA_00386 4.4e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
MLLIABJA_00387 1.3e-222 cotH M CotH kinase protein
MLLIABJA_00388 3e-96 P VTC domain
MLLIABJA_00389 2.7e-83 S membrane
MLLIABJA_00390 1.3e-135 G Domain of unknown function (DUF4832)
MLLIABJA_00391 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLLIABJA_00392 4.8e-11 S Protein of unknown function (DUF1146)
MLLIABJA_00393 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLLIABJA_00394 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
MLLIABJA_00395 7.7e-155 endA F DNA RNA non-specific endonuclease
MLLIABJA_00396 2.9e-111 tcyB_2 P ABC transporter (permease)
MLLIABJA_00397 1.9e-116 gltJ P ABC transporter (Permease
MLLIABJA_00398 3.2e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLLIABJA_00399 2.5e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_00400 2.5e-110 tcyB_2 P ABC transporter (permease)
MLLIABJA_00401 1.9e-116 gltJ P ABC transporter (Permease
MLLIABJA_00402 1.1e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLLIABJA_00403 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_00404 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLLIABJA_00405 8.4e-230 vicK 2.7.13.3 T Histidine kinase
MLLIABJA_00406 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MLLIABJA_00407 6.7e-57 S Protein of unknown function (DUF454)
MLLIABJA_00408 1.9e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MLLIABJA_00409 1.8e-145 yidA S hydrolases of the HAD superfamily
MLLIABJA_00410 4.1e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
MLLIABJA_00411 7.7e-67 ywiB S Domain of unknown function (DUF1934)
MLLIABJA_00412 0.0 pacL 3.6.3.8 P cation transport ATPase
MLLIABJA_00413 1.8e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MLLIABJA_00414 5.4e-158 yjjH S Calcineurin-like phosphoesterase
MLLIABJA_00415 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLLIABJA_00416 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLLIABJA_00417 3.2e-124 ftsE D cell division ATP-binding protein FtsE
MLLIABJA_00418 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLLIABJA_00419 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLLIABJA_00420 9.5e-177 yubA S permease
MLLIABJA_00421 8.3e-224 G COG0457 FOG TPR repeat
MLLIABJA_00422 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MLLIABJA_00423 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLLIABJA_00424 1.6e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MLLIABJA_00425 8.6e-87 ebsA S Family of unknown function (DUF5322)
MLLIABJA_00426 5.6e-17 M LysM domain
MLLIABJA_00427 1.4e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MLLIABJA_00428 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLLIABJA_00429 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MLLIABJA_00430 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLLIABJA_00431 2.1e-74 XK27_03610 K Gnat family
MLLIABJA_00432 1.8e-87 yybC
MLLIABJA_00433 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MLLIABJA_00434 2.2e-273 pepV 3.5.1.18 E Dipeptidase
MLLIABJA_00435 1.1e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
MLLIABJA_00436 2.5e-226 V Glucan-binding protein C
MLLIABJA_00437 2.5e-253 V Glucan-binding protein C
MLLIABJA_00438 9.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MLLIABJA_00439 1.7e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLLIABJA_00440 3.2e-95 S Protein of unknown function (DUF1697)
MLLIABJA_00441 1.6e-143 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLLIABJA_00442 8.1e-54 S LemA family
MLLIABJA_00443 1.1e-159 clcA_2 P chloride
MLLIABJA_00444 1.8e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
MLLIABJA_00445 3.7e-131 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MLLIABJA_00446 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MLLIABJA_00447 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MLLIABJA_00448 3.5e-110 cps4C M biosynthesis protein
MLLIABJA_00449 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
MLLIABJA_00450 1.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MLLIABJA_00451 4.8e-221 rgpAc GT4 M group 1 family protein
MLLIABJA_00452 3.4e-211 wcoF M Glycosyltransferase, group 1 family protein
MLLIABJA_00453 7.1e-118 Z012_10770 M Domain of unknown function (DUF1919)
MLLIABJA_00454 6.5e-163 M Glycosyltransferase, group 2 family protein
MLLIABJA_00455 1.2e-153 M Glycosyltransferase like family 2
MLLIABJA_00456 1.5e-174
MLLIABJA_00457 7e-251 epsU S Polysaccharide biosynthesis protein
MLLIABJA_00458 3.4e-159 S Acyltransferase family
MLLIABJA_00459 1.7e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
MLLIABJA_00460 3e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MLLIABJA_00461 4.1e-187 wbbI M transferase activity, transferring glycosyl groups
MLLIABJA_00463 1.5e-152 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLLIABJA_00464 9.1e-107 pgm G Belongs to the phosphoglycerate mutase family
MLLIABJA_00465 2.8e-108 G Belongs to the phosphoglycerate mutase family
MLLIABJA_00466 8.1e-108 G Belongs to the phosphoglycerate mutase family
MLLIABJA_00467 4.7e-197 S hmm pf01594
MLLIABJA_00468 2e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLLIABJA_00469 4.9e-39 S granule-associated protein
MLLIABJA_00470 3.4e-286 S unusual protein kinase
MLLIABJA_00471 4.5e-101 estA E Lysophospholipase L1 and related esterases
MLLIABJA_00472 3e-156 rssA S Phospholipase, patatin family
MLLIABJA_00473 5.9e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MLLIABJA_00474 1.1e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MLLIABJA_00475 4.9e-213 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLLIABJA_00476 1.2e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLLIABJA_00477 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLLIABJA_00478 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MLLIABJA_00479 7.9e-225 2.7.13.3 T protein histidine kinase activity
MLLIABJA_00480 3.1e-202 hpk9 2.7.13.3 T protein histidine kinase activity
MLLIABJA_00481 9.6e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MLLIABJA_00482 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLLIABJA_00483 1.8e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLLIABJA_00484 0.0 lpdA 1.8.1.4 C Dehydrogenase
MLLIABJA_00485 0.0 3.5.1.28 NU amidase activity
MLLIABJA_00486 1.3e-78 3.5.1.28 NU amidase activity
MLLIABJA_00487 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
MLLIABJA_00488 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MLLIABJA_00489 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
MLLIABJA_00490 1.4e-231 ycdB P peroxidase
MLLIABJA_00491 2e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MLLIABJA_00492 2.3e-117 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLLIABJA_00493 3.9e-24 tatA U protein secretion
MLLIABJA_00494 8.8e-212 msmX P Belongs to the ABC transporter superfamily
MLLIABJA_00495 4.1e-150 malG P ABC transporter (Permease
MLLIABJA_00496 1.4e-248 malF P ABC transporter (Permease
MLLIABJA_00497 4.3e-228 malX G ABC transporter
MLLIABJA_00498 1.6e-172 malR K Transcriptional regulator
MLLIABJA_00499 1.6e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MLLIABJA_00500 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLLIABJA_00501 1.5e-38
MLLIABJA_00502 5.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
MLLIABJA_00503 3.9e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MLLIABJA_00504 0.0 pepN 3.4.11.2 E aminopeptidase
MLLIABJA_00505 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
MLLIABJA_00506 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLLIABJA_00507 4.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLLIABJA_00508 9.1e-156 pstA P phosphate transport system permease
MLLIABJA_00509 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
MLLIABJA_00510 2.6e-155 pstS P phosphate
MLLIABJA_00511 1.8e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MLLIABJA_00512 5.5e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MLLIABJA_00513 1e-44 yktA S Belongs to the UPF0223 family
MLLIABJA_00514 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLLIABJA_00515 3.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MLLIABJA_00516 7.3e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLLIABJA_00517 7.2e-237 XK27_04775 S hemerythrin HHE cation binding domain
MLLIABJA_00518 2.7e-35 M1-755 P Hemerythrin HHE cation binding domain protein
MLLIABJA_00519 2.1e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MLLIABJA_00520 1.2e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLLIABJA_00521 1.4e-136 S haloacid dehalogenase-like hydrolase
MLLIABJA_00522 9.5e-239 metY 2.5.1.49 E o-acetylhomoserine
MLLIABJA_00523 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MLLIABJA_00524 1.4e-237 agcS E (Alanine) symporter
MLLIABJA_00525 2e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLLIABJA_00526 1e-168 bglC K Transcriptional regulator
MLLIABJA_00527 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MLLIABJA_00528 4.2e-81 yecS P ABC transporter (Permease
MLLIABJA_00529 1.8e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
MLLIABJA_00530 5.5e-235 nylA 3.5.1.4 J Belongs to the amidase family
MLLIABJA_00531 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLLIABJA_00532 1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLLIABJA_00533 6.5e-103
MLLIABJA_00534 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLLIABJA_00535 2.9e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLLIABJA_00536 4.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MLLIABJA_00537 2.2e-132 S TraX protein
MLLIABJA_00538 2.5e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MLLIABJA_00539 2.3e-271 S Psort location CytoplasmicMembrane, score
MLLIABJA_00540 1.5e-231 dinF V Mate efflux family protein
MLLIABJA_00541 3.2e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
MLLIABJA_00542 0.0 V Type III restriction enzyme, res subunit
MLLIABJA_00543 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MLLIABJA_00544 2.1e-132 2.4.2.3 F Phosphorylase superfamily
MLLIABJA_00546 2.6e-186 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
MLLIABJA_00547 1.4e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MLLIABJA_00548 5.8e-158 czcD P cation diffusion facilitator family transporter
MLLIABJA_00549 1.2e-94 K Transcriptional regulator, TetR family
MLLIABJA_00550 4.1e-70 S Protein of unknown function with HXXEE motif
MLLIABJA_00551 9.2e-11
MLLIABJA_00552 1.3e-137 pnuC H nicotinamide mononucleotide transporter
MLLIABJA_00553 8.2e-140 S Phenazine biosynthesis protein
MLLIABJA_00554 5.7e-92 tetR K transcriptional regulator
MLLIABJA_00555 4.3e-124 V abc transporter atp-binding protein
MLLIABJA_00556 0.0 V ABC transporter (Permease
MLLIABJA_00557 3.3e-10 L Integrase core domain protein
MLLIABJA_00558 1.6e-217 ftsW D Belongs to the SEDS family
MLLIABJA_00559 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLLIABJA_00560 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLLIABJA_00561 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLLIABJA_00563 6.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLLIABJA_00564 1.7e-159 holB 2.7.7.7 L dna polymerase iii
MLLIABJA_00565 5.2e-134 yaaT S stage 0 sporulation protein
MLLIABJA_00566 1.2e-54 yabA L Involved in initiation control of chromosome replication
MLLIABJA_00567 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLLIABJA_00568 2.3e-226 amt P Ammonium Transporter
MLLIABJA_00569 1.9e-53 glnB K Belongs to the P(II) protein family
MLLIABJA_00570 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
MLLIABJA_00571 9.7e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MLLIABJA_00572 3.4e-81 S Bacterial inner membrane protein
MLLIABJA_00573 1.2e-112 3.4.17.14, 3.5.1.28 NU amidase activity
MLLIABJA_00574 4.2e-292 nptA P COG1283 Na phosphate symporter
MLLIABJA_00575 1.9e-209 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLLIABJA_00576 4.8e-219 S membrane
MLLIABJA_00577 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MLLIABJA_00578 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MLLIABJA_00579 1.7e-38 ynzC S UPF0291 protein
MLLIABJA_00580 6e-255 cycA E permease
MLLIABJA_00581 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLLIABJA_00582 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_00583 1.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLLIABJA_00587 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
MLLIABJA_00588 1.4e-56 S ABC-2 type transporter
MLLIABJA_00589 1.8e-96
MLLIABJA_00591 4.7e-168 fhuR K transcriptional regulator (lysR family)
MLLIABJA_00592 1.4e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLLIABJA_00593 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLLIABJA_00594 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLLIABJA_00595 8.9e-221 pyrP F uracil Permease
MLLIABJA_00596 3.8e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MLLIABJA_00597 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MLLIABJA_00598 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MLLIABJA_00599 1.6e-124 2.1.1.223 S Putative SAM-dependent methyltransferase
MLLIABJA_00600 9.8e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLLIABJA_00601 3.4e-121 macB V ABC transporter, ATP-binding protein
MLLIABJA_00602 6.5e-213 V permease protein
MLLIABJA_00603 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLLIABJA_00604 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLLIABJA_00607 1.7e-230 2.7.13.3 T GHKL domain
MLLIABJA_00608 5.3e-133 agrA KT Response regulator of the LytR AlgR family
MLLIABJA_00610 2.1e-21 S Antitoxin component of a toxin-antitoxin (TA) module
MLLIABJA_00611 9.5e-31 XK27_00530 M CHAP domain protein
MLLIABJA_00612 6.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
MLLIABJA_00613 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLLIABJA_00614 1.8e-28 K DNA-binding transcription factor activity
MLLIABJA_00615 0.0 mdlB V abc transporter atp-binding protein
MLLIABJA_00616 0.0 lmrA V abc transporter atp-binding protein
MLLIABJA_00617 2.1e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLLIABJA_00618 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLLIABJA_00619 9e-197 yceA S Belongs to the UPF0176 family
MLLIABJA_00620 1e-27 XK27_00085 K Transcriptional
MLLIABJA_00621 6e-24
MLLIABJA_00622 2.9e-134 deoD_1 2.4.2.3 F Phosphorylase superfamily
MLLIABJA_00623 8.7e-114 S VIT family
MLLIABJA_00624 2.6e-138 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLLIABJA_00625 5.9e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLLIABJA_00626 6.2e-194 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MLLIABJA_00628 5e-137 E Alpha beta hydrolase
MLLIABJA_00629 2.8e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLLIABJA_00630 3.8e-138 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MLLIABJA_00631 2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MLLIABJA_00632 4.6e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MLLIABJA_00633 1.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLLIABJA_00634 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MLLIABJA_00635 1.3e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLLIABJA_00636 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MLLIABJA_00637 2.9e-25
MLLIABJA_00638 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLLIABJA_00639 0.0 U protein secretion
MLLIABJA_00640 3.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MLLIABJA_00641 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MLLIABJA_00642 8.8e-10
MLLIABJA_00643 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLLIABJA_00644 2e-145 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLLIABJA_00645 1.5e-202 S Protein of unknown function (DUF3114)
MLLIABJA_00646 4.1e-29 pspC KT PspC domain protein
MLLIABJA_00647 7.5e-118 yqfA K protein, Hemolysin III
MLLIABJA_00648 1.1e-77 K hmm pf08876
MLLIABJA_00649 1.7e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MLLIABJA_00650 1.1e-209 mvaS 2.3.3.10 I synthase
MLLIABJA_00651 1.1e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLLIABJA_00652 4.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLLIABJA_00653 9.7e-22
MLLIABJA_00654 1.3e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLLIABJA_00655 3.3e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
MLLIABJA_00656 7.5e-250 mmuP E amino acid
MLLIABJA_00657 3e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MLLIABJA_00658 2.2e-30 S Domain of unknown function (DUF1912)
MLLIABJA_00659 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
MLLIABJA_00660 7.4e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLLIABJA_00661 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLLIABJA_00662 4.2e-147 aadK G adenylyltransferase
MLLIABJA_00663 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLLIABJA_00664 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
MLLIABJA_00665 3.7e-16 S Protein of unknown function (DUF2969)
MLLIABJA_00668 7.1e-204 rpsA 1.17.7.4 J ribosomal protein S1
MLLIABJA_00671 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
MLLIABJA_00672 2.1e-115 M Pfam SNARE associated Golgi protein
MLLIABJA_00673 7.3e-228 murN 2.3.2.16 V FemAB family
MLLIABJA_00674 6.4e-171 S oxidoreductase
MLLIABJA_00675 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
MLLIABJA_00676 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MLLIABJA_00677 0.0 clpE O Belongs to the ClpA ClpB family
MLLIABJA_00678 1.8e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLLIABJA_00679 1e-34 ykuJ S protein conserved in bacteria
MLLIABJA_00680 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MLLIABJA_00681 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_00682 3.1e-78 feoA P FeoA domain protein
MLLIABJA_00683 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MLLIABJA_00684 6.6e-08
MLLIABJA_00685 1.3e-150 I Alpha/beta hydrolase family
MLLIABJA_00686 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLLIABJA_00687 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLLIABJA_00688 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MLLIABJA_00689 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLLIABJA_00690 7.1e-150 licT K antiterminator
MLLIABJA_00691 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLLIABJA_00692 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MLLIABJA_00693 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLLIABJA_00694 1.2e-149 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLLIABJA_00695 1.5e-101 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLLIABJA_00696 2.7e-222 mdtG EGP Major facilitator Superfamily
MLLIABJA_00697 2e-33 secG U Preprotein translocase subunit SecG
MLLIABJA_00698 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLLIABJA_00699 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MLLIABJA_00700 4.8e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLLIABJA_00701 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MLLIABJA_00702 4.9e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MLLIABJA_00703 3.2e-181 ccpA K Catabolite control protein A
MLLIABJA_00704 2.9e-201 yyaQ S YjbR
MLLIABJA_00705 1.1e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MLLIABJA_00706 3.9e-78 yueI S Protein of unknown function (DUF1694)
MLLIABJA_00707 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLLIABJA_00708 1.2e-25 WQ51_00785
MLLIABJA_00709 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLLIABJA_00710 1.3e-218 ywbD 2.1.1.191 J Methyltransferase
MLLIABJA_00711 9.2e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLLIABJA_00712 2.8e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLLIABJA_00713 6.5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLLIABJA_00714 2.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLLIABJA_00715 2.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MLLIABJA_00716 3.6e-52 yheA S Belongs to the UPF0342 family
MLLIABJA_00717 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MLLIABJA_00718 7.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLLIABJA_00719 2.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLLIABJA_00720 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
MLLIABJA_00721 1.3e-249 msrR K Transcriptional regulator
MLLIABJA_00722 7.4e-156 ydiA P C4-dicarboxylate transporter malic acid transport
MLLIABJA_00723 2.7e-202 I acyl-CoA dehydrogenase
MLLIABJA_00724 2e-97 mip S hydroperoxide reductase activity
MLLIABJA_00725 6.7e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLLIABJA_00726 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
MLLIABJA_00727 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
MLLIABJA_00728 1.6e-61 smtB K Transcriptional regulator
MLLIABJA_00729 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLLIABJA_00731 5.5e-141 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLLIABJA_00732 1.5e-74 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
MLLIABJA_00733 4.4e-127 S CAAX amino terminal protease family protein
MLLIABJA_00734 2e-97 J Acetyltransferase (GNAT) domain
MLLIABJA_00735 4e-96
MLLIABJA_00736 8.8e-113 K Bacterial regulatory proteins, tetR family
MLLIABJA_00737 1e-115 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLLIABJA_00738 7.9e-129 bcrA V abc transporter atp-binding protein
MLLIABJA_00739 6.5e-296 V ABC transporter transmembrane region
MLLIABJA_00740 1.7e-12
MLLIABJA_00741 1.8e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLLIABJA_00742 5.8e-132 S Domain of unknown function (DUF4336)
MLLIABJA_00743 2e-203 yeaN P transporter
MLLIABJA_00744 5.1e-148 yitS S EDD domain protein, DegV family
MLLIABJA_00745 9.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
MLLIABJA_00746 4.3e-98 ypgQ F HD superfamily hydrolase
MLLIABJA_00747 1.3e-127 S CAAX amino terminal protease family
MLLIABJA_00748 3.2e-110 cutC P Participates in the control of copper homeostasis
MLLIABJA_00750 7.8e-20 S Domain of unknown function (DUF4767)
MLLIABJA_00751 5.6e-282 norB P Major facilitator superfamily
MLLIABJA_00752 6.3e-91 tetR K transcriptional regulator
MLLIABJA_00753 9.2e-150 S Domain of unknown function (DUF4300)
MLLIABJA_00754 7.1e-117 V CAAX protease self-immunity
MLLIABJA_00755 1.4e-160 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLLIABJA_00756 2.2e-134 fecE 3.6.3.34 HP ABC transporter
MLLIABJA_00757 2.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MLLIABJA_00758 6.5e-125 ybbA S Putative esterase
MLLIABJA_00759 2.5e-158 yegS 2.7.1.107 I Diacylglycerol kinase
MLLIABJA_00760 8e-172 S Domain of unknown function (DUF389)
MLLIABJA_00762 2.3e-29 S Membrane
MLLIABJA_00763 4.7e-97
MLLIABJA_00764 1.5e-22 S Small integral membrane protein
MLLIABJA_00765 7.7e-68 S Asp23 family, cell envelope-related function
MLLIABJA_00766 3.3e-08 K CsbD-like
MLLIABJA_00767 3.3e-08 K CsbD-like
MLLIABJA_00768 6.6e-174 pdhD 1.8.1.4 C Dehydrogenase
MLLIABJA_00769 1.5e-165 acoA C Acetoin dehydrogenase E1 component subunit alpha
MLLIABJA_00770 7.8e-175 acoB C dehydrogenase E1 component
MLLIABJA_00771 1e-141 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLLIABJA_00772 4.2e-80 Q Methyltransferase domain
MLLIABJA_00773 3.4e-74 K TetR family transcriptional regulator
MLLIABJA_00774 7.1e-47
MLLIABJA_00775 2.8e-126 V CAAX protease self-immunity
MLLIABJA_00776 1.2e-10
MLLIABJA_00777 1.3e-19 M Bacterial lipoprotein
MLLIABJA_00778 4.1e-60 S Protein of unknown function (DUF1722)
MLLIABJA_00779 2.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
MLLIABJA_00781 3e-49
MLLIABJA_00782 8.4e-119 estA E GDSL-like Lipase/Acylhydrolase
MLLIABJA_00783 1.2e-101
MLLIABJA_00784 2.1e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
MLLIABJA_00785 9.9e-149 ycgQ S TIGR03943 family
MLLIABJA_00786 2.4e-156 XK27_03015 S permease
MLLIABJA_00788 0.0 yhgF K Transcriptional accessory protein
MLLIABJA_00789 2.9e-41 pspC KT PspC domain
MLLIABJA_00790 2.2e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLLIABJA_00791 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLLIABJA_00792 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLLIABJA_00793 3e-67 ytxH S General stress protein
MLLIABJA_00795 1.5e-177 yegQ O Peptidase U32
MLLIABJA_00796 3.7e-251 yegQ O Peptidase U32
MLLIABJA_00797 2.5e-87 bioY S biotin synthase
MLLIABJA_00799 1.1e-33 XK27_12190 S protein conserved in bacteria
MLLIABJA_00800 7.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
MLLIABJA_00801 9.5e-11
MLLIABJA_00802 7.8e-09
MLLIABJA_00803 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MLLIABJA_00804 1e-134 M LysM domain
MLLIABJA_00805 8.4e-23
MLLIABJA_00806 5.2e-175 S hydrolase
MLLIABJA_00807 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLLIABJA_00808 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MLLIABJA_00809 4.8e-235 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLLIABJA_00810 1.1e-234 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MLLIABJA_00812 3e-60 divIC D Septum formation initiator
MLLIABJA_00813 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLLIABJA_00814 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLLIABJA_00815 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLLIABJA_00816 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLLIABJA_00817 1.1e-29 yyzM S Protein conserved in bacteria
MLLIABJA_00818 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLLIABJA_00819 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLLIABJA_00820 2.9e-134 parB K Belongs to the ParB family
MLLIABJA_00821 1.5e-204 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MLLIABJA_00822 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLLIABJA_00823 3.4e-118 yoaK S Protein of unknown function (DUF1275)
MLLIABJA_00827 0.0 XK27_10405 S Bacterial membrane protein YfhO
MLLIABJA_00828 4.3e-305 ybiT S abc transporter atp-binding protein
MLLIABJA_00829 7.1e-153 yvjA S membrane
MLLIABJA_00830 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLLIABJA_00831 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLLIABJA_00832 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLLIABJA_00833 6.4e-58 yaaA S S4 domain protein YaaA
MLLIABJA_00834 1.1e-228 ymfF S Peptidase M16
MLLIABJA_00835 7.5e-236 ymfH S Peptidase M16
MLLIABJA_00836 5.7e-131 S sequence-specific DNA binding
MLLIABJA_00837 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLLIABJA_00838 5.3e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLLIABJA_00839 8.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLLIABJA_00840 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLLIABJA_00841 2e-71 lytE M LysM domain protein
MLLIABJA_00842 6.6e-61 isaA GH23 M Immunodominant staphylococcal antigen A
MLLIABJA_00843 2.8e-310 S Bacterial membrane protein, YfhO
MLLIABJA_00844 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLLIABJA_00845 2.1e-98 yvbG U UPF0056 membrane protein
MLLIABJA_00846 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLLIABJA_00847 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MLLIABJA_00848 2.2e-73 rplI J binds to the 23S rRNA
MLLIABJA_00849 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLLIABJA_00850 1.8e-47 veg S Biofilm formation stimulator VEG
MLLIABJA_00851 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLLIABJA_00852 1.1e-10
MLLIABJA_00853 3.5e-53 ypaA M Membrane
MLLIABJA_00854 4.6e-94 XK27_06935 K transcriptional regulator
MLLIABJA_00855 2.1e-159 XK27_06930 V domain protein
MLLIABJA_00856 7.4e-107 S Putative adhesin
MLLIABJA_00857 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
MLLIABJA_00858 1.8e-53 K transcriptional regulator, PadR family
MLLIABJA_00859 7e-115 nudL L hydrolase
MLLIABJA_00864 0.0
MLLIABJA_00865 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
MLLIABJA_00866 2.1e-151 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MLLIABJA_00868 5.8e-162 T Diguanylate cyclase
MLLIABJA_00869 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MLLIABJA_00870 9.5e-47 fruR K transcriptional
MLLIABJA_00871 1.3e-92 L Transposase
MLLIABJA_00872 7.3e-61 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
MLLIABJA_00873 6.8e-221 sip L Belongs to the 'phage' integrase family
MLLIABJA_00874 2.8e-28 S MerR HTH family regulatory protein
MLLIABJA_00875 2.1e-206 S Replication initiation factor
MLLIABJA_00876 2.7e-121 D ftsk spoiiie
MLLIABJA_00880 2.9e-46 K DNA-binding protein
MLLIABJA_00881 1.6e-79
MLLIABJA_00884 3.3e-28
MLLIABJA_00885 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLLIABJA_00886 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MLLIABJA_00887 5.6e-219 metE 2.1.1.14 E Methionine synthase
MLLIABJA_00888 3.8e-129 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_00889 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_00890 5e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
MLLIABJA_00892 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MLLIABJA_00893 2.7e-166 XK27_01785 S cog cog1284
MLLIABJA_00894 4e-122 yaaA S Belongs to the UPF0246 family
MLLIABJA_00895 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLLIABJA_00896 2.4e-89 XK27_10930 K acetyltransferase
MLLIABJA_00897 7.5e-14
MLLIABJA_00898 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MLLIABJA_00899 1.1e-287 ccs S the current gene model (or a revised gene model) may contain a frame shift
MLLIABJA_00900 2.1e-43 yrzB S Belongs to the UPF0473 family
MLLIABJA_00901 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLLIABJA_00902 6.3e-44 yrzL S Belongs to the UPF0297 family
MLLIABJA_00903 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MLLIABJA_00904 3.5e-233 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MLLIABJA_00906 8.5e-215 int L Belongs to the 'phage' integrase family
MLLIABJA_00907 1.9e-18 S Domain of unknown function (DUF3173)
MLLIABJA_00908 1.2e-156 L Replication initiation factor
MLLIABJA_00909 5.5e-89 K TRANSCRIPTIONal
MLLIABJA_00910 1.8e-79 S Short repeat of unknown function (DUF308)
MLLIABJA_00911 1.6e-172 yeiH S membrane
MLLIABJA_00912 4.7e-197 ltrA S Low temperature requirement protein
MLLIABJA_00914 2.9e-90 adk 2.7.4.3 F topology modulation protein
MLLIABJA_00915 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLLIABJA_00916 1.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLLIABJA_00917 2.8e-35 XK27_09805 S MORN repeat protein
MLLIABJA_00918 0.0 XK27_09800 I Acyltransferase
MLLIABJA_00919 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLLIABJA_00920 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MLLIABJA_00921 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLLIABJA_00922 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MLLIABJA_00923 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLLIABJA_00924 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLLIABJA_00925 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLLIABJA_00926 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLLIABJA_00927 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLLIABJA_00928 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLLIABJA_00929 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MLLIABJA_00930 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLLIABJA_00931 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLLIABJA_00932 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLLIABJA_00933 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLLIABJA_00934 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLLIABJA_00935 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLLIABJA_00936 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLLIABJA_00937 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLLIABJA_00938 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLLIABJA_00939 1.9e-23 rpmD J ribosomal protein l30
MLLIABJA_00940 5.7e-58 rplO J binds to the 23S rRNA
MLLIABJA_00941 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLLIABJA_00942 1.1e-116 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLLIABJA_00943 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLLIABJA_00944 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MLLIABJA_00945 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLLIABJA_00946 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLLIABJA_00947 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLLIABJA_00948 4.4e-62 rplQ J ribosomal protein l17
MLLIABJA_00949 4.8e-246 6.3.2.2 H gamma-glutamylcysteine synthetase
MLLIABJA_00951 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
MLLIABJA_00952 1.2e-186 L Phage integrase family
MLLIABJA_00953 5.7e-15
MLLIABJA_00954 9.8e-225 K Replication initiation factor
MLLIABJA_00955 2.4e-36 ydcQ D Ftsk spoiiie family protein
MLLIABJA_00956 5e-73
MLLIABJA_00957 1.7e-42
MLLIABJA_00958 5.5e-50 K Transcriptional
MLLIABJA_00959 1.8e-77 S Haloacid dehalogenase-like hydrolase
MLLIABJA_00960 5.2e-123 lacR K DeoR C terminal sensor domain
MLLIABJA_00961 6.7e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
MLLIABJA_00962 1.3e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
MLLIABJA_00963 5e-179 lacD 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MLLIABJA_00964 2.4e-50 lacF 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MLLIABJA_00965 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
MLLIABJA_00966 3.9e-286 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MLLIABJA_00967 6.4e-173 lacX G Aldose 1-epimerase
MLLIABJA_00970 5.7e-95 ywlG S Belongs to the UPF0340 family
MLLIABJA_00971 1.9e-124 treR K trehalose operon
MLLIABJA_00972 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_00973 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MLLIABJA_00974 0.0 pepO 3.4.24.71 O Peptidase family M13
MLLIABJA_00975 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MLLIABJA_00978 2.7e-277 thrC 4.2.3.1 E Threonine synthase
MLLIABJA_00979 1.2e-225 norN V Mate efflux family protein
MLLIABJA_00980 1.4e-57 asp S cog cog1302
MLLIABJA_00981 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
MLLIABJA_00982 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLLIABJA_00983 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MLLIABJA_00984 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
MLLIABJA_00985 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLLIABJA_00986 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLLIABJA_00987 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLLIABJA_00988 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLLIABJA_00989 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLLIABJA_00990 1e-68 S cog cog4699
MLLIABJA_00991 3.5e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLLIABJA_00992 9.7e-144 cglB U protein transport across the cell outer membrane
MLLIABJA_00993 4.7e-41 comGC U Required for transformation and DNA binding
MLLIABJA_00994 2.4e-69 cglD NU Competence protein
MLLIABJA_00995 3.1e-15 NU Type II secretory pathway pseudopilin
MLLIABJA_00996 2e-71 comGF U Competence protein ComGF
MLLIABJA_00997 2e-12 comGF U Putative Competence protein ComGF
MLLIABJA_00998 4.7e-174 ytxK 2.1.1.72 L DNA methylase
MLLIABJA_00999 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLLIABJA_01000 8.8e-27 lanR K sequence-specific DNA binding
MLLIABJA_01001 5.2e-108 V CAAX protease self-immunity
MLLIABJA_01003 1.1e-100 S CAAX amino terminal protease family protein
MLLIABJA_01004 2.2e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLLIABJA_01005 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MLLIABJA_01006 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
MLLIABJA_01007 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLLIABJA_01008 7.6e-09 S NTF2 fold immunity protein
MLLIABJA_01009 9.7e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLLIABJA_01010 3.7e-117 S CAAX protease self-immunity
MLLIABJA_01011 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLLIABJA_01012 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLLIABJA_01016 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
MLLIABJA_01017 1.2e-137 S HAD hydrolase, family IA, variant
MLLIABJA_01018 4.5e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLLIABJA_01019 1.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLLIABJA_01020 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLLIABJA_01021 1.7e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MLLIABJA_01022 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLLIABJA_01023 1.3e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MLLIABJA_01024 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
MLLIABJA_01025 6.2e-140 fnt P Formate nitrite transporter
MLLIABJA_01026 7.9e-230 XK27_09615 C reductase
MLLIABJA_01027 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
MLLIABJA_01028 1e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MLLIABJA_01029 6.4e-77 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
MLLIABJA_01030 3.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLLIABJA_01031 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
MLLIABJA_01032 5.9e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MLLIABJA_01033 4.6e-50 S Protein of unknown function (DUF3397)
MLLIABJA_01034 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLLIABJA_01035 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLLIABJA_01036 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MLLIABJA_01037 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLLIABJA_01038 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MLLIABJA_01039 3e-151 hpk9 2.7.13.3 T protein histidine kinase activity
MLLIABJA_01040 3.6e-206 hpk9 2.7.13.3 T protein histidine kinase activity
MLLIABJA_01041 2.6e-223 fasC 2.7.13.3 T protein histidine kinase activity
MLLIABJA_01042 8.2e-126 fasA KT Response regulator of the LytR AlgR family
MLLIABJA_01043 3.8e-216 L the current gene model (or a revised gene model) may contain a frame shift
MLLIABJA_01045 0.0 M domain protein
MLLIABJA_01046 3.5e-80 M Pilin isopeptide linkage domain protein
MLLIABJA_01048 4.1e-09
MLLIABJA_01050 3.6e-192 XK27_10075 S abc transporter atp-binding protein
MLLIABJA_01051 0.0 V abc transporter atp-binding protein
MLLIABJA_01052 3.4e-295 V abc transporter atp-binding protein
MLLIABJA_01053 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MLLIABJA_01055 4.4e-283 S Protein of unknown function (DUF3114)
MLLIABJA_01056 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
MLLIABJA_01057 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MLLIABJA_01058 1.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MLLIABJA_01059 3.4e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
MLLIABJA_01060 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLLIABJA_01061 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLLIABJA_01062 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MLLIABJA_01063 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MLLIABJA_01064 1.2e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MLLIABJA_01065 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MLLIABJA_01066 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLLIABJA_01069 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLLIABJA_01070 6.7e-171 vraS 2.7.13.3 T Histidine kinase
MLLIABJA_01071 1.5e-116 yvqF S Membrane
MLLIABJA_01072 2.9e-102 kcsA P Ion transport protein
MLLIABJA_01073 1.5e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
MLLIABJA_01074 1.5e-135 stp 3.1.3.16 T phosphatase
MLLIABJA_01075 1.8e-240 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLLIABJA_01076 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLLIABJA_01077 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLLIABJA_01078 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MLLIABJA_01079 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MLLIABJA_01080 9.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLLIABJA_01081 4.6e-146 XK27_02985 S overlaps another CDS with the same product name
MLLIABJA_01082 1.4e-147 supH S overlaps another CDS with the same product name
MLLIABJA_01083 2.8e-61 yvoA_1 K Transcriptional
MLLIABJA_01084 2.4e-119 skfE V abc transporter atp-binding protein
MLLIABJA_01085 5.3e-131 V Psort location CytoplasmicMembrane, score
MLLIABJA_01086 2.1e-171 oppF P Belongs to the ABC transporter superfamily
MLLIABJA_01087 4.6e-202 oppD P Belongs to the ABC transporter superfamily
MLLIABJA_01088 3.8e-165 amiD P ABC transporter (Permease
MLLIABJA_01089 8.1e-274 amiC P ABC transporter (Permease
MLLIABJA_01090 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
MLLIABJA_01091 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MLLIABJA_01092 6.3e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MLLIABJA_01093 3.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MLLIABJA_01094 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLLIABJA_01095 6.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MLLIABJA_01096 2.4e-101 yjbK S Adenylate cyclase
MLLIABJA_01097 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLLIABJA_01098 1e-204 iscS 2.8.1.7 E Cysteine desulfurase
MLLIABJA_01099 8.2e-60 XK27_04120 S Putative amino acid metabolism
MLLIABJA_01100 7.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLLIABJA_01101 4.4e-129 puuD T peptidase C26
MLLIABJA_01102 1.7e-117 radC E Belongs to the UPF0758 family
MLLIABJA_01103 2.3e-277 rgpF M Rhamnan synthesis protein F
MLLIABJA_01104 2.8e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLLIABJA_01105 8.9e-142 rgpC GM Transport permease protein
MLLIABJA_01106 1.9e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
MLLIABJA_01107 5.9e-224 rgpA GT4 M Domain of unknown function (DUF1972)
MLLIABJA_01108 1.3e-224 GT4 M transferase activity, transferring glycosyl groups
MLLIABJA_01109 7.3e-220 M Psort location CytoplasmicMembrane, score
MLLIABJA_01110 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
MLLIABJA_01111 4.1e-109
MLLIABJA_01112 2.6e-154 2.4.1.60 S Glycosyltransferase group 2 family protein
MLLIABJA_01113 1.6e-42 S Uncharacterized conserved protein (DUF2304)
MLLIABJA_01114 1.9e-127 arnC M group 2 family protein
MLLIABJA_01115 4.4e-180 cpsIaJ S Glycosyltransferase like family 2
MLLIABJA_01116 3.2e-175 M Glycosyltransferase, group 2 family protein
MLLIABJA_01117 1.8e-221 amrA S membrane protein involved in the export of O-antigen and teichoic acid
MLLIABJA_01118 5.3e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLLIABJA_01119 1.8e-265 S Glucosyl transferase GtrII
MLLIABJA_01120 8.9e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MLLIABJA_01121 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MLLIABJA_01122 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLLIABJA_01123 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLLIABJA_01124 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLLIABJA_01125 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MLLIABJA_01126 4.7e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
MLLIABJA_01127 2e-208 arcT 2.6.1.1 E Aminotransferase
MLLIABJA_01128 9.4e-136 ET Belongs to the bacterial solute-binding protein 3 family
MLLIABJA_01129 7.1e-139 ET ABC transporter
MLLIABJA_01130 9.5e-80 mutT 3.6.1.55 F Nudix family
MLLIABJA_01132 1.3e-20 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLLIABJA_01133 3.9e-113 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MLLIABJA_01134 2.7e-88 MA20_25245 K Gnat family
MLLIABJA_01135 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLLIABJA_01137 1.1e-164 S CAAX amino terminal protease family protein
MLLIABJA_01138 8.5e-207 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MLLIABJA_01139 1.1e-168 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MLLIABJA_01140 1.6e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_01141 2.2e-17 XK27_00735
MLLIABJA_01142 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLLIABJA_01144 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLLIABJA_01145 9.8e-10 O ADP-ribosylglycohydrolase
MLLIABJA_01146 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
MLLIABJA_01147 3.5e-61 ycaO O OsmC-like protein
MLLIABJA_01149 7e-148 EG Permeases of the drug metabolite transporter (DMT) superfamily
MLLIABJA_01151 2.6e-112 serB 3.1.3.3 E phosphoserine phosphatase
MLLIABJA_01152 8.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLLIABJA_01153 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLLIABJA_01154 1.8e-93 3.1.3.18 S IA, variant 1
MLLIABJA_01155 1.1e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLLIABJA_01156 5.9e-56 lrgA S Effector of murein hydrolase LrgA
MLLIABJA_01158 3.9e-57 arsC 1.20.4.1 P Belongs to the ArsC family
MLLIABJA_01159 1.3e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MLLIABJA_01160 2.9e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLLIABJA_01161 1.1e-103 wecD M Acetyltransferase (GNAT) domain
MLLIABJA_01162 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLLIABJA_01163 9.8e-158 GK ROK family
MLLIABJA_01164 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
MLLIABJA_01165 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
MLLIABJA_01166 1.8e-203 potD P spermidine putrescine ABC transporter
MLLIABJA_01167 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
MLLIABJA_01168 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
MLLIABJA_01169 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MLLIABJA_01170 6.2e-168 murB 1.3.1.98 M cell wall formation
MLLIABJA_01171 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLLIABJA_01172 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLLIABJA_01173 2.7e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MLLIABJA_01174 1.3e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLLIABJA_01175 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
MLLIABJA_01176 0.0 ydaO E amino acid
MLLIABJA_01177 5.1e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLLIABJA_01178 1.5e-36 ylqC L Belongs to the UPF0109 family
MLLIABJA_01179 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MLLIABJA_01181 1.3e-211 2.7.13.3 T protein histidine kinase activity
MLLIABJA_01182 2.2e-123 agrA KT phosphorelay signal transduction system
MLLIABJA_01183 1e-161 O protein import
MLLIABJA_01184 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MLLIABJA_01185 9.8e-18 yjdB S Domain of unknown function (DUF4767)
MLLIABJA_01186 2.8e-196 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLLIABJA_01188 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
MLLIABJA_01189 1.3e-71 S QueT transporter
MLLIABJA_01191 4.1e-173 yfjR K regulation of single-species biofilm formation
MLLIABJA_01193 3.7e-48 yhaI J Protein of unknown function (DUF805)
MLLIABJA_01195 1.4e-94
MLLIABJA_01196 6.7e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLLIABJA_01197 8.1e-46 ftsL D cell division protein FtsL
MLLIABJA_01198 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MLLIABJA_01199 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLLIABJA_01200 1.2e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLLIABJA_01202 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLLIABJA_01203 2.6e-60 yutD J protein conserved in bacteria
MLLIABJA_01204 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLLIABJA_01205 5.5e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
MLLIABJA_01208 0.0 mdlA V abc transporter atp-binding protein
MLLIABJA_01209 0.0 mdlB V abc transporter atp-binding protein
MLLIABJA_01210 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
MLLIABJA_01216 7.5e-46 spiA K sequence-specific DNA binding
MLLIABJA_01218 6.7e-07
MLLIABJA_01219 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MLLIABJA_01220 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MLLIABJA_01221 1.2e-94 V CAAX protease self-immunity
MLLIABJA_01222 4.7e-137 cppA E CppA N-terminal
MLLIABJA_01223 5.7e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MLLIABJA_01225 1.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLLIABJA_01226 4.3e-141 cah 4.2.1.1 P carbonic anhydrase
MLLIABJA_01227 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MLLIABJA_01228 1.1e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLLIABJA_01229 3.6e-35
MLLIABJA_01230 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MLLIABJA_01231 3e-162 yxeN P ABC transporter (Permease
MLLIABJA_01232 7.9e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_01233 5e-10 S Protein of unknown function (DUF4059)
MLLIABJA_01234 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLLIABJA_01235 2.5e-92 rsmD 2.1.1.171 L Methyltransferase
MLLIABJA_01236 2.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLLIABJA_01237 7.1e-187 ylbL T Belongs to the peptidase S16 family
MLLIABJA_01238 4.6e-182 yhcC S radical SAM protein
MLLIABJA_01239 3.2e-95 ytqB 2.1.1.176 J (SAM)-dependent
MLLIABJA_01241 0.0 yjcE P NhaP-type Na H and K H antiporters
MLLIABJA_01242 6.6e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MLLIABJA_01243 4.9e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MLLIABJA_01244 4.3e-10 MU outer membrane autotransporter barrel domain protein
MLLIABJA_01245 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLLIABJA_01247 9e-75 XK27_03180 T universal stress protein
MLLIABJA_01248 5.8e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MLLIABJA_01249 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLLIABJA_01250 4.4e-100 pncA Q isochorismatase
MLLIABJA_01251 6.4e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLLIABJA_01252 3.3e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MLLIABJA_01253 8.2e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
MLLIABJA_01254 3.7e-190 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MLLIABJA_01255 4.9e-231 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MLLIABJA_01256 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLLIABJA_01257 6.5e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLLIABJA_01258 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLLIABJA_01260 1.7e-281 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLLIABJA_01261 1.6e-30 S PQ loop repeat
MLLIABJA_01262 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
MLLIABJA_01263 7e-273 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
MLLIABJA_01264 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
MLLIABJA_01265 9.1e-60
MLLIABJA_01266 3.8e-214 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLLIABJA_01267 4.8e-61
MLLIABJA_01268 1.9e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MLLIABJA_01269 1.5e-34 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLLIABJA_01270 2.3e-98 yqeG S hydrolase of the HAD superfamily
MLLIABJA_01271 8.6e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLLIABJA_01272 7.7e-49 yhbY J RNA-binding protein
MLLIABJA_01273 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLLIABJA_01274 9.2e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MLLIABJA_01275 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLLIABJA_01276 2.5e-138 yqeM Q Methyltransferase domain protein
MLLIABJA_01277 4.2e-195 ylbM S Belongs to the UPF0348 family
MLLIABJA_01279 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MLLIABJA_01280 4.1e-43
MLLIABJA_01282 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLLIABJA_01283 3.7e-131 ecsA V abc transporter atp-binding protein
MLLIABJA_01284 1.9e-173 ecsB U Bacterial ABC transporter protein EcsB
MLLIABJA_01285 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
MLLIABJA_01286 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLLIABJA_01288 4e-223 ytfP S Flavoprotein
MLLIABJA_01289 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLLIABJA_01290 8.2e-63 XK27_02560 S cog cog2151
MLLIABJA_01291 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
MLLIABJA_01292 3.2e-104 dnaQ 2.7.7.7 L DNA polymerase III
MLLIABJA_01293 8.9e-125 K transcriptional regulator, MerR family
MLLIABJA_01294 0.0 V ABC transporter (Permease
MLLIABJA_01295 1.9e-124 V abc transporter atp-binding protein
MLLIABJA_01297 7.8e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLLIABJA_01298 6.5e-50
MLLIABJA_01299 1.8e-47
MLLIABJA_01300 0.0 ctpE P E1-E2 ATPase
MLLIABJA_01301 1.2e-59
MLLIABJA_01302 4.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
MLLIABJA_01303 1.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLLIABJA_01304 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MLLIABJA_01305 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLLIABJA_01306 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MLLIABJA_01307 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MLLIABJA_01308 7.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLLIABJA_01309 9.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLLIABJA_01311 2.1e-73 copY K negative regulation of transcription, DNA-templated
MLLIABJA_01312 0.0 copA 3.6.3.54 P P-type ATPase
MLLIABJA_01313 8e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MLLIABJA_01314 4.6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MLLIABJA_01315 1.1e-113 papP P ABC transporter (Permease
MLLIABJA_01316 3e-106 P ABC transporter (Permease
MLLIABJA_01317 9.9e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
MLLIABJA_01318 9.7e-155 cjaA ET ABC transporter substrate-binding protein
MLLIABJA_01322 2.1e-252 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLLIABJA_01323 1.4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
MLLIABJA_01324 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MLLIABJA_01325 1.7e-99 thiT S Thiamine transporter
MLLIABJA_01326 3.3e-62 yjqA S Bacterial PH domain
MLLIABJA_01327 6.2e-152 corA P CorA-like protein
MLLIABJA_01328 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLLIABJA_01329 3e-41 yazA L endonuclease containing a URI domain
MLLIABJA_01330 1.3e-139 yabB 2.1.1.223 L Methyltransferase
MLLIABJA_01331 1.9e-148 nodB3 G deacetylase
MLLIABJA_01332 4.9e-142 plsC 2.3.1.51 I Acyltransferase
MLLIABJA_01333 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MLLIABJA_01334 0.0 comEC S Competence protein ComEC
MLLIABJA_01335 7.9e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLLIABJA_01336 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MLLIABJA_01337 3e-232 ytoI K transcriptional regulator containing CBS domains
MLLIABJA_01338 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MLLIABJA_01339 3.3e-156 rbn E Belongs to the UPF0761 family
MLLIABJA_01340 1.7e-85 ccl S cog cog4708
MLLIABJA_01341 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLLIABJA_01342 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLLIABJA_01343 0.0 WQ51_06230 S ABC transporter
MLLIABJA_01344 1.4e-142 cmpC S abc transporter atp-binding protein
MLLIABJA_01345 2.7e-40 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLLIABJA_01346 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLLIABJA_01348 4.2e-44
MLLIABJA_01349 5.8e-55 S TM2 domain
MLLIABJA_01350 3.6e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLLIABJA_01351 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLLIABJA_01352 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLLIABJA_01353 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
MLLIABJA_01354 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MLLIABJA_01355 1.3e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MLLIABJA_01356 5.6e-144 cof S Sucrose-6F-phosphate phosphohydrolase
MLLIABJA_01357 5e-134 glcR K transcriptional regulator (DeoR family)
MLLIABJA_01358 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLLIABJA_01359 1e-73 K helix_turn_helix multiple antibiotic resistance protein
MLLIABJA_01360 2.5e-228 S COG1073 Hydrolases of the alpha beta superfamily
MLLIABJA_01361 2.3e-151 cylA V abc transporter atp-binding protein
MLLIABJA_01362 1.8e-129 cylB V ABC-2 type transporter
MLLIABJA_01363 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
MLLIABJA_01364 2e-31 S Protein of unknown function (DUF3021)
MLLIABJA_01365 1.2e-121 mta K Transcriptional
MLLIABJA_01366 2.5e-121 yhcA V abc transporter atp-binding protein
MLLIABJA_01367 6.3e-214 macB_2 V FtsX-like permease family
MLLIABJA_01368 9.3e-275 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLLIABJA_01369 2.9e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLLIABJA_01370 1.7e-73 yhaI S Protein of unknown function (DUF805)
MLLIABJA_01371 2.6e-255 pepC 3.4.22.40 E aminopeptidase
MLLIABJA_01372 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLLIABJA_01373 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLLIABJA_01374 5.8e-94 ypsA S Belongs to the UPF0398 family
MLLIABJA_01375 1.6e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLLIABJA_01376 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MLLIABJA_01377 4.3e-278 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MLLIABJA_01378 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MLLIABJA_01379 4.8e-22
MLLIABJA_01380 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MLLIABJA_01381 1e-84 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
MLLIABJA_01382 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLLIABJA_01383 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLLIABJA_01384 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLLIABJA_01385 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MLLIABJA_01386 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLLIABJA_01387 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MLLIABJA_01388 4.8e-96 ybhL S Belongs to the BI1 family
MLLIABJA_01389 4.2e-12 ycdA S Domain of unknown function (DUF4352)
MLLIABJA_01390 1.2e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLLIABJA_01391 1.8e-90 K transcriptional regulator
MLLIABJA_01392 1.6e-36 yneF S UPF0154 protein
MLLIABJA_01393 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLLIABJA_01394 1.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLLIABJA_01395 6.6e-98 XK27_09740 S Phosphoesterase
MLLIABJA_01396 8.3e-87 ykuL S CBS domain
MLLIABJA_01397 1.6e-132 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MLLIABJA_01398 9e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLLIABJA_01399 1.1e-93 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLLIABJA_01400 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLLIABJA_01401 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
MLLIABJA_01402 4.2e-259 trkH P Cation transport protein
MLLIABJA_01403 2.2e-246 trkA P Potassium transporter peripheral membrane component
MLLIABJA_01404 2.4e-92 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLLIABJA_01405 2.1e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLLIABJA_01406 4.7e-101 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MLLIABJA_01407 5.1e-154 K sequence-specific DNA binding
MLLIABJA_01408 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MLLIABJA_01409 4.9e-54 yhaI L Membrane
MLLIABJA_01410 2.5e-253 S Domain of unknown function (DUF4173)
MLLIABJA_01411 3.1e-137 ET ABC transporter substrate-binding protein
MLLIABJA_01412 1.2e-163 metQ M Belongs to the NlpA lipoprotein family
MLLIABJA_01413 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MLLIABJA_01414 1.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLLIABJA_01415 8e-99 metI P ABC transporter (Permease
MLLIABJA_01416 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MLLIABJA_01417 4.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MLLIABJA_01418 8e-94 S UPF0397 protein
MLLIABJA_01419 3.9e-309 ykoD P abc transporter atp-binding protein
MLLIABJA_01420 4.5e-149 cbiQ P cobalt transport
MLLIABJA_01421 2.3e-119 ktrA P COG0569 K transport systems, NAD-binding component
MLLIABJA_01422 5.6e-237 P COG0168 Trk-type K transport systems, membrane components
MLLIABJA_01423 2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MLLIABJA_01424 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
MLLIABJA_01425 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLLIABJA_01426 4.6e-280 T PhoQ Sensor
MLLIABJA_01427 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLLIABJA_01428 8.8e-215 dnaB L Replication initiation and membrane attachment
MLLIABJA_01429 4.4e-166 dnaI L Primosomal protein DnaI
MLLIABJA_01430 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MLLIABJA_01431 3.4e-112
MLLIABJA_01432 6.4e-227 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLLIABJA_01433 2.5e-62 manO S protein conserved in bacteria
MLLIABJA_01434 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
MLLIABJA_01435 2e-117 manM G pts system
MLLIABJA_01436 4.9e-174 manL 2.7.1.191 G pts system
MLLIABJA_01437 2e-67 manO S Protein conserved in bacteria
MLLIABJA_01438 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
MLLIABJA_01439 4.7e-135 manY G pts system
MLLIABJA_01440 6.2e-169 manL 2.7.1.191 G pts system
MLLIABJA_01441 3e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MLLIABJA_01442 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MLLIABJA_01443 1.6e-247 pbuO S permease
MLLIABJA_01444 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MLLIABJA_01445 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
MLLIABJA_01446 5.7e-188 brpA K Transcriptional
MLLIABJA_01447 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
MLLIABJA_01448 4e-199 nusA K Participates in both transcription termination and antitermination
MLLIABJA_01449 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MLLIABJA_01450 8.8e-41 ylxQ J ribosomal protein
MLLIABJA_01451 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLLIABJA_01452 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLLIABJA_01453 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
MLLIABJA_01454 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLLIABJA_01455 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MLLIABJA_01456 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MLLIABJA_01457 4.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
MLLIABJA_01458 2.6e-219 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLLIABJA_01459 1.9e-298 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
MLLIABJA_01460 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MLLIABJA_01461 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLLIABJA_01462 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLLIABJA_01463 1.9e-72 ylbF S Belongs to the UPF0342 family
MLLIABJA_01464 9.3e-46 ylbG S UPF0298 protein
MLLIABJA_01465 1.9e-209 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MLLIABJA_01466 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
MLLIABJA_01467 3.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MLLIABJA_01468 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MLLIABJA_01469 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MLLIABJA_01470 1.7e-111 acuB S CBS domain
MLLIABJA_01471 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLLIABJA_01472 8.5e-108 yvyE 3.4.13.9 S YigZ family
MLLIABJA_01473 2.7e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLLIABJA_01474 3.8e-82 comFC K competence protein
MLLIABJA_01475 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLLIABJA_01476 1.1e-121 M domain protein
MLLIABJA_01477 6.7e-89 H Methyltransferase
MLLIABJA_01478 1.4e-22 XK27_10050 K Peptidase S24-like
MLLIABJA_01481 1.1e-41
MLLIABJA_01485 6.3e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MLLIABJA_01487 3.1e-54
MLLIABJA_01488 2.3e-262 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLLIABJA_01489 4.8e-96
MLLIABJA_01491 1.4e-19
MLLIABJA_01492 2.1e-32
MLLIABJA_01493 4e-132 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLLIABJA_01494 8.4e-15 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
MLLIABJA_01495 2.7e-18 V endonuclease activity
MLLIABJA_01496 1.2e-47 L DNA synthesis involved in DNA repair
MLLIABJA_01499 4.4e-82 S Protein conserved in bacteria
MLLIABJA_01502 1.2e-07
MLLIABJA_01503 4.2e-32
MLLIABJA_01504 1.6e-140 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MLLIABJA_01505 0.0 D nuclear chromosome segregation
MLLIABJA_01506 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
MLLIABJA_01507 2.9e-226 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
MLLIABJA_01508 3.7e-17
MLLIABJA_01510 1.6e-41 xisC L viral genome integration into host DNA
MLLIABJA_01512 2.1e-14
MLLIABJA_01514 3.2e-113 U AAA-like domain
MLLIABJA_01515 2.1e-29
MLLIABJA_01517 2.1e-25
MLLIABJA_01518 5.8e-53 I mechanosensitive ion channel activity
MLLIABJA_01519 5.2e-45
MLLIABJA_01521 2.2e-130 clpB O C-terminal, D2-small domain, of ClpB protein
MLLIABJA_01524 8.9e-44
MLLIABJA_01525 5.5e-09 tetD K transcription activator, effector binding
MLLIABJA_01526 3.4e-247 S Protein of unknown function DUF262
MLLIABJA_01528 2.2e-78 XK27_01300 P Protein conserved in bacteria
MLLIABJA_01529 2.3e-79 FNV0100 F Belongs to the Nudix hydrolase family
MLLIABJA_01530 2.1e-117 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MLLIABJA_01531 1.7e-105 abiGI K Transcriptional regulator, AbiEi antitoxin
MLLIABJA_01539 4.3e-30 radC E Belongs to the UPF0758 family
MLLIABJA_01544 1.1e-08 S ERF superfamily
MLLIABJA_01545 7.1e-65 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MLLIABJA_01546 2.8e-33 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLLIABJA_01547 4.7e-252 T Pfam Adenylate and Guanylate cyclase catalytic domain
MLLIABJA_01548 6.8e-84 immA E Zn peptidase
MLLIABJA_01550 3.7e-32 3.4.24.40 M G5
MLLIABJA_01551 5.8e-73 L IS861 transposase
MLLIABJA_01552 4.6e-275 V ABC transporter transmembrane region
MLLIABJA_01554 9.2e-10 2.7.7.73, 2.7.7.80 H ThiF family
MLLIABJA_01557 2.3e-143 K Helix-turn-helix XRE-family like proteins
MLLIABJA_01558 2e-59 3.5.1.28 NU GBS Bsp-like repeat
MLLIABJA_01559 1.7e-11 3.5.1.28 NU GBS Bsp-like repeat
MLLIABJA_01566 1e-129 U TraM recognition site of TraD and TraG
MLLIABJA_01568 9.8e-21 S Ribosomal protein S1-like RNA-binding domain
MLLIABJA_01570 2.5e-202 3.2.1.97, 4.2.2.1 GH101,PL8 N Leucine rich repeats (6 copies)
MLLIABJA_01571 2.8e-51 spd F DNA RNA non-specific endonuclease
MLLIABJA_01572 2.5e-21 xerS L Belongs to the 'phage' integrase family
MLLIABJA_01573 4.7e-08 L Psort location Cytoplasmic, score 8.96
MLLIABJA_01575 4.1e-25 soj D ATPases involved in chromosome partitioning
MLLIABJA_01576 2.6e-29 dnaG L DNA primase activity
MLLIABJA_01577 1.1e-72 S Region found in RelA / SpoT proteins
MLLIABJA_01578 7.3e-17 L Protein of unknown function (DUF3991)
MLLIABJA_01579 1.4e-38 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLLIABJA_01580 4.1e-12 S PcfK-like protein
MLLIABJA_01581 9e-58 S PcfJ-like protein
MLLIABJA_01583 5e-16
MLLIABJA_01584 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
MLLIABJA_01586 6e-20 M Pilin isopeptide linkage domain protein
MLLIABJA_01589 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
MLLIABJA_01590 1.1e-102 S Domain of unknown function (DUF1803)
MLLIABJA_01591 7.8e-102 ygaC J Belongs to the UPF0374 family
MLLIABJA_01592 3.1e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
MLLIABJA_01593 1.7e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLLIABJA_01594 2e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
MLLIABJA_01595 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
MLLIABJA_01596 2.4e-110 S HAD hydrolase, family IA, variant 3
MLLIABJA_01597 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MLLIABJA_01598 5.2e-72 marR K Transcriptional regulator, MarR family
MLLIABJA_01599 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLLIABJA_01600 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLLIABJA_01601 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MLLIABJA_01602 3.3e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MLLIABJA_01603 1.1e-125 IQ reductase
MLLIABJA_01604 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLLIABJA_01605 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLLIABJA_01606 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLLIABJA_01607 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLLIABJA_01608 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLLIABJA_01609 2e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLLIABJA_01610 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLLIABJA_01611 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
MLLIABJA_01612 4.1e-125 fruR K transcriptional
MLLIABJA_01613 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MLLIABJA_01614 0.0 fruA 2.7.1.202 G phosphotransferase system
MLLIABJA_01615 1.1e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLLIABJA_01616 7.6e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLLIABJA_01618 8.8e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MLLIABJA_01619 7.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLLIABJA_01620 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MLLIABJA_01621 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MLLIABJA_01622 1.6e-94 2.3.1.128 K acetyltransferase
MLLIABJA_01623 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MLLIABJA_01624 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MLLIABJA_01625 4.4e-129 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLLIABJA_01627 2.6e-13
MLLIABJA_01628 5e-63 WQ51_03320 S cog cog4835
MLLIABJA_01629 1.5e-147 XK27_08360 S EDD domain protein, DegV family
MLLIABJA_01630 3.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLLIABJA_01631 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLLIABJA_01632 0.0 yfmR S abc transporter atp-binding protein
MLLIABJA_01633 1.3e-26 U response to pH
MLLIABJA_01634 4.5e-127 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MLLIABJA_01635 1.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MLLIABJA_01636 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLLIABJA_01637 8.6e-277 S Psort location CytoplasmicMembrane, score
MLLIABJA_01638 6.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MLLIABJA_01639 3.3e-74 K DNA-binding transcription factor activity
MLLIABJA_01640 0.0 lmrA1 V abc transporter atp-binding protein
MLLIABJA_01641 0.0 lmrA2 V abc transporter atp-binding protein
MLLIABJA_01642 7.4e-112 K Acetyltransferase (GNAT) family
MLLIABJA_01643 9.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
MLLIABJA_01644 3.7e-117 T response regulator
MLLIABJA_01645 1.4e-215 sptS 2.7.13.3 T Histidine kinase
MLLIABJA_01646 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MLLIABJA_01647 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLLIABJA_01648 1.7e-159 cvfB S Protein conserved in bacteria
MLLIABJA_01649 3.7e-34 yozE S Belongs to the UPF0346 family
MLLIABJA_01650 2e-119 sip M LysM domain protein
MLLIABJA_01651 3.7e-188 phoH T phosphate starvation-inducible protein PhoH
MLLIABJA_01655 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLLIABJA_01656 2.9e-159 S reductase
MLLIABJA_01657 4.7e-168 K transcriptional regulator (lysR family)
MLLIABJA_01658 7.7e-108 S CAAX amino terminal protease family protein
MLLIABJA_01659 2e-272 S Glucan-binding protein C
MLLIABJA_01660 1.5e-175 coiA 3.6.4.12 S Competence protein
MLLIABJA_01661 0.0 pepF E oligoendopeptidase F
MLLIABJA_01662 2.2e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
MLLIABJA_01663 5.2e-119 yrrM 2.1.1.104 S O-Methyltransferase
MLLIABJA_01664 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MLLIABJA_01665 3e-84 yxjI S LURP-one-related
MLLIABJA_01666 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLLIABJA_01669 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MLLIABJA_01670 1.7e-93 agrA KT response regulator
MLLIABJA_01671 5.3e-07
MLLIABJA_01672 1.8e-133 agrA KT phosphorelay signal transduction system
MLLIABJA_01673 7e-229 2.7.13.3 T GHKL domain
MLLIABJA_01675 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
MLLIABJA_01676 3.1e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLLIABJA_01677 2.6e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MLLIABJA_01678 1.7e-185 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLLIABJA_01679 3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLLIABJA_01680 1.4e-122 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MLLIABJA_01681 4.8e-202 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MLLIABJA_01682 1e-127 yxkH G deacetylase
MLLIABJA_01683 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MLLIABJA_01684 1.2e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLLIABJA_01685 4.9e-85 rarD S Transporter
MLLIABJA_01686 2.9e-15 T peptidase
MLLIABJA_01687 3e-14 coiA 3.6.4.12 S Competence protein
MLLIABJA_01688 6.6e-47 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLLIABJA_01689 5.8e-42 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLLIABJA_01690 2.6e-100 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
MLLIABJA_01691 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MLLIABJA_01692 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLLIABJA_01693 3.2e-174 L DNA restriction-modification system
MLLIABJA_01694 0.0 T Histidine kinase
MLLIABJA_01695 2.2e-95
MLLIABJA_01696 3.3e-107 L HNH endonuclease
MLLIABJA_01697 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLLIABJA_01698 6e-118 atpB C it plays a direct role in the translocation of protons across the membrane
MLLIABJA_01699 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLLIABJA_01700 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLLIABJA_01701 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLLIABJA_01702 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLLIABJA_01703 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLLIABJA_01704 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MLLIABJA_01705 5.3e-119 liaI S membrane
MLLIABJA_01706 1.5e-74 XK27_02470 K LytTr DNA-binding domain
MLLIABJA_01707 1.1e-309 KT response to antibiotic
MLLIABJA_01708 3.6e-78 yebC M Membrane
MLLIABJA_01709 1.1e-259 XK27_03190 S hydrolases of the HAD superfamily
MLLIABJA_01710 7.1e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLLIABJA_01712 2.4e-30 yozG K Transcriptional regulator
MLLIABJA_01716 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLLIABJA_01717 5.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLLIABJA_01718 1.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLLIABJA_01719 1.6e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MLLIABJA_01720 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MLLIABJA_01721 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLLIABJA_01723 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLLIABJA_01724 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MLLIABJA_01725 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_01726 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
MLLIABJA_01727 9.2e-178 scrR K Transcriptional regulator
MLLIABJA_01728 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLLIABJA_01729 1.7e-61 yqhY S protein conserved in bacteria
MLLIABJA_01730 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLLIABJA_01731 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
MLLIABJA_01732 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MLLIABJA_01734 3e-145 V 'abc transporter, ATP-binding protein
MLLIABJA_01735 2.1e-32 blpT
MLLIABJA_01738 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MLLIABJA_01739 6.5e-168 corA P COG0598 Mg2 and Co2 transporters
MLLIABJA_01740 3.8e-122 XK27_01040 S Protein of unknown function (DUF1129)
MLLIABJA_01742 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLLIABJA_01743 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLLIABJA_01744 1.1e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MLLIABJA_01745 5.5e-42 XK27_05745
MLLIABJA_01746 1.9e-223 L Transposase
MLLIABJA_01747 1.1e-222 mutY L A G-specific adenine glycosylase
MLLIABJA_01749 2.9e-09
MLLIABJA_01750 1.6e-38
MLLIABJA_01752 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLLIABJA_01753 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLLIABJA_01754 9.1e-90 cvpA S toxin biosynthetic process
MLLIABJA_01755 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLLIABJA_01756 2.7e-152 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLLIABJA_01757 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MLLIABJA_01758 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLLIABJA_01759 1.3e-46 azlD S branched-chain amino acid
MLLIABJA_01760 1.5e-113 azlC E AzlC protein
MLLIABJA_01761 9.6e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLLIABJA_01762 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLLIABJA_01763 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MLLIABJA_01764 4.3e-33 ykzG S Belongs to the UPF0356 family
MLLIABJA_01765 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLLIABJA_01766 8e-114 pscB M CHAP domain protein
MLLIABJA_01767 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
MLLIABJA_01768 2.5e-62 glnR K Transcriptional regulator
MLLIABJA_01769 3e-87 S Fusaric acid resistance protein-like
MLLIABJA_01770 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MLLIABJA_01771 6.6e-117
MLLIABJA_01772 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
MLLIABJA_01773 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLLIABJA_01774 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLLIABJA_01775 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLLIABJA_01776 4e-142 purR 2.4.2.7 F operon repressor
MLLIABJA_01777 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
MLLIABJA_01778 4.2e-170 rmuC S RmuC domain protein
MLLIABJA_01779 7.3e-115 thiN 2.7.6.2 H thiamine pyrophosphokinase
MLLIABJA_01780 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MLLIABJA_01781 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLLIABJA_01783 2.9e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLLIABJA_01784 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLLIABJA_01785 4e-142 tatD L Hydrolase, tatd
MLLIABJA_01786 9.8e-71 yccU S CoA-binding protein
MLLIABJA_01787 9.1e-50 trxA O Belongs to the thioredoxin family
MLLIABJA_01788 1.7e-142 S Macro domain protein
MLLIABJA_01789 7.3e-58 L thioesterase
MLLIABJA_01790 5.5e-53 bta 1.8.1.8 CO cell redox homeostasis
MLLIABJA_01792 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLLIABJA_01793 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MLLIABJA_01794 1.2e-143 cdsA 2.7.7.41 S Belongs to the CDS family
MLLIABJA_01795 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLLIABJA_01796 7.7e-47 yajC U protein transport
MLLIABJA_01797 6.1e-126 yeeN K transcriptional regulatory protein
MLLIABJA_01798 1.6e-280 V ABC transporter
MLLIABJA_01799 1.3e-146 Z012_04635 K sequence-specific DNA binding
MLLIABJA_01800 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
MLLIABJA_01801 5.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MLLIABJA_01802 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MLLIABJA_01803 8.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MLLIABJA_01804 6.6e-129 adcB P ABC transporter (Permease
MLLIABJA_01805 2.4e-135 adcC P ABC transporter, ATP-binding protein
MLLIABJA_01806 2e-71 adcR K transcriptional
MLLIABJA_01807 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLLIABJA_01808 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLLIABJA_01809 2.7e-26
MLLIABJA_01810 2.9e-273 sufB O assembly protein SufB
MLLIABJA_01811 2.7e-73 nifU C SUF system FeS assembly protein, NifU family
MLLIABJA_01812 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLLIABJA_01813 9.1e-234 sufD O assembly protein SufD
MLLIABJA_01814 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLLIABJA_01815 5.7e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
MLLIABJA_01816 2.9e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MLLIABJA_01817 5.4e-17 S Protein of unknown function (DUF3021)
MLLIABJA_01818 3.4e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLLIABJA_01819 3.9e-271 glnP P ABC transporter
MLLIABJA_01820 2.2e-123 glnQ E abc transporter atp-binding protein
MLLIABJA_01821 2.4e-177 D nuclear chromosome segregation
MLLIABJA_01822 1.7e-81 V VanZ like family
MLLIABJA_01823 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLLIABJA_01824 2.9e-194 yhjX P Major Facilitator
MLLIABJA_01825 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MLLIABJA_01826 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLLIABJA_01827 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLLIABJA_01828 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MLLIABJA_01829 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLLIABJA_01830 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLLIABJA_01831 3.1e-83 nrdI F Belongs to the NrdI family
MLLIABJA_01832 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MLLIABJA_01833 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLLIABJA_01834 1.1e-175 prmA J Ribosomal protein L11 methyltransferase
MLLIABJA_01835 3.5e-74 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MLLIABJA_01836 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
MLLIABJA_01837 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLLIABJA_01838 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLLIABJA_01839 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLLIABJA_01840 3.1e-139 ykuT M mechanosensitive ion channel
MLLIABJA_01841 3.9e-87 sigH K DNA-templated transcription, initiation
MLLIABJA_01843 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLLIABJA_01844 8.4e-138 divIVA D Cell division initiation protein
MLLIABJA_01845 1.8e-142 ylmH S conserved protein, contains S4-like domain
MLLIABJA_01846 2.9e-30 yggT D integral membrane protein
MLLIABJA_01847 1.8e-99 sepF D cell septum assembly
MLLIABJA_01848 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLLIABJA_01849 7.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLLIABJA_01850 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLLIABJA_01851 1.5e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLLIABJA_01852 1.2e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLLIABJA_01853 3.9e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLLIABJA_01855 0.0 typA T GTP-binding protein TypA
MLLIABJA_01856 1e-176 glk 2.7.1.2 G Glucokinase
MLLIABJA_01857 7.1e-27 yqgQ S protein conserved in bacteria
MLLIABJA_01858 3.4e-79 perR P Belongs to the Fur family
MLLIABJA_01859 1.1e-89 dps P Belongs to the Dps family
MLLIABJA_01860 6.6e-103 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MLLIABJA_01861 1.1e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MLLIABJA_01862 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MLLIABJA_01863 3.5e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
MLLIABJA_01864 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MLLIABJA_01865 5.6e-65 S Domain of unknown function (DUF4430)
MLLIABJA_01866 1.6e-74 S Psort location CytoplasmicMembrane, score
MLLIABJA_01867 2.8e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
MLLIABJA_01868 4.6e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
MLLIABJA_01869 1.2e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
MLLIABJA_01870 5e-119 sirR K iron dependent repressor
MLLIABJA_01871 4e-135 htpX O Belongs to the peptidase M48B family
MLLIABJA_01872 7.7e-92 lemA S LemA family
MLLIABJA_01873 5.6e-170 spd F DNA RNA non-specific endonuclease
MLLIABJA_01874 0.0 2.4.1.21 GT5 M Right handed beta helix region
MLLIABJA_01876 4.5e-137 S double-stranded DNA endodeoxyribonuclease activity
MLLIABJA_01877 6.2e-304 hsdM 2.1.1.72 V type I restriction-modification system
MLLIABJA_01878 1.9e-135 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
MLLIABJA_01881 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MLLIABJA_01883 9.4e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLLIABJA_01884 1.9e-209 MA20_36090 S Protein of unknown function (DUF2974)
MLLIABJA_01885 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLLIABJA_01886 8.9e-153 5.2.1.8 G hydrolase
MLLIABJA_01887 1.3e-26 P Hemerythrin HHE cation binding domain protein
MLLIABJA_01888 9.3e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MLLIABJA_01889 7.4e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLLIABJA_01890 3.6e-114 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MLLIABJA_01901 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MLLIABJA_01902 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLLIABJA_01903 1.7e-227 cinA 3.5.1.42 S Belongs to the CinA family
MLLIABJA_01904 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MLLIABJA_01905 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLLIABJA_01907 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLLIABJA_01909 4.2e-69 K LytTr DNA-binding domain
MLLIABJA_01910 6e-79 S Protein of unknown function (DUF3021)
MLLIABJA_01911 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLLIABJA_01912 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MLLIABJA_01913 3.4e-68 argR K Regulates arginine biosynthesis genes
MLLIABJA_01914 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MLLIABJA_01916 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLLIABJA_01917 7.4e-135 J Domain of unknown function (DUF4041)
MLLIABJA_01918 6.2e-32
MLLIABJA_01919 3.2e-175 1.1.1.169 H Ketopantoate reductase
MLLIABJA_01920 6.1e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLLIABJA_01921 1e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLLIABJA_01922 4.2e-239 purD 6.3.4.13 F Belongs to the GARS family
MLLIABJA_01923 1.3e-156 S CHAP domain
MLLIABJA_01924 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MLLIABJA_01925 9.9e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLLIABJA_01926 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MLLIABJA_01927 1.1e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLLIABJA_01928 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLLIABJA_01929 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MLLIABJA_01930 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLLIABJA_01931 2.7e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLLIABJA_01932 1e-139 recO L Involved in DNA repair and RecF pathway recombination
MLLIABJA_01933 1.9e-217 araT 2.6.1.1 E Aminotransferase
MLLIABJA_01934 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLLIABJA_01935 1.9e-84 usp 3.5.1.28 CBM50 S CHAP domain
MLLIABJA_01936 6.1e-83 mreD M rod shape-determining protein MreD
MLLIABJA_01937 6.6e-92 mreC M Involved in formation and maintenance of cell shape
MLLIABJA_01943 2.6e-10
MLLIABJA_01948 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLLIABJA_01949 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MLLIABJA_01950 2.2e-125 gntR1 K transcriptional
MLLIABJA_01951 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLLIABJA_01952 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLLIABJA_01953 2.7e-86
MLLIABJA_01954 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
MLLIABJA_01955 5.3e-127 K DNA-binding helix-turn-helix protein
MLLIABJA_01956 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLLIABJA_01957 4.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLLIABJA_01958 2.2e-165 GK ROK family
MLLIABJA_01959 3.5e-157 dprA LU DNA protecting protein DprA
MLLIABJA_01960 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLLIABJA_01961 1.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MLLIABJA_01962 4.8e-54 V ABC-2 family transporter protein
MLLIABJA_01964 1e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLLIABJA_01965 1.7e-225 T PhoQ Sensor
MLLIABJA_01966 3.6e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLLIABJA_01967 1.1e-222 XK27_05470 E Methionine synthase
MLLIABJA_01968 1.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLLIABJA_01969 9.1e-44 pspE P Rhodanese-like protein
MLLIABJA_01970 8.2e-137 IQ Acetoin reductase
MLLIABJA_01972 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLLIABJA_01975 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MLLIABJA_01976 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MLLIABJA_01977 2.3e-40 C Pyridoxamine 5'-phosphate oxidase
MLLIABJA_01978 7.6e-96 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MLLIABJA_01979 9.4e-12 S Macro domain
MLLIABJA_01980 4e-36 S Macro domain
MLLIABJA_01981 2.2e-73 mgrA K Transcriptional regulator, MarR family
MLLIABJA_01982 4.4e-147 1.6.5.2 GM epimerase
MLLIABJA_01983 1.6e-129 proV E abc transporter atp-binding protein
MLLIABJA_01984 7.8e-264 proWX P ABC transporter
MLLIABJA_01985 4.1e-110 magIII L Base excision DNA repair protein, HhH-GPD family
MLLIABJA_01990 2.6e-10
MLLIABJA_01993 1.9e-07
MLLIABJA_01998 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLLIABJA_01999 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLLIABJA_02000 5.5e-36 XK27_02060 S Transglycosylase associated protein
MLLIABJA_02001 3.9e-72 badR K Transcriptional regulator, marr family
MLLIABJA_02002 3.2e-95 S reductase
MLLIABJA_02004 9.2e-289 ahpF O alkyl hydroperoxide reductase
MLLIABJA_02005 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
MLLIABJA_02006 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
MLLIABJA_02007 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLLIABJA_02008 1.6e-82 S Putative small multi-drug export protein
MLLIABJA_02009 2e-74 ctsR K Belongs to the CtsR family
MLLIABJA_02010 0.0 clpC O Belongs to the ClpA ClpB family
MLLIABJA_02011 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLLIABJA_02012 2.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLLIABJA_02013 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLLIABJA_02014 1.1e-138 S SseB protein N-terminal domain
MLLIABJA_02015 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
MLLIABJA_02017 2.4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLLIABJA_02018 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLLIABJA_02020 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLLIABJA_02021 2.7e-91 yacP S RNA-binding protein containing a PIN domain
MLLIABJA_02022 1.1e-150 degV S DegV family
MLLIABJA_02024 5.1e-22 K Transcriptional
MLLIABJA_02025 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLLIABJA_02026 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MLLIABJA_02027 7.4e-80 hmpT S cog cog4720
MLLIABJA_02028 1.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MLLIABJA_02029 1.1e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLLIABJA_02030 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLLIABJA_02031 7.5e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
MLLIABJA_02032 6e-303 dnaK O Heat shock 70 kDa protein
MLLIABJA_02033 5.7e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLLIABJA_02034 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLLIABJA_02035 7.9e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
MLLIABJA_02036 1.3e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MLLIABJA_02037 2.8e-131 ais G Phosphoglycerate mutase
MLLIABJA_02038 9.6e-242 XK27_08635 S UPF0210 protein
MLLIABJA_02039 2.3e-38 gcvR T UPF0237 protein
MLLIABJA_02040 1.6e-232 capA M Bacterial capsule synthesis protein
MLLIABJA_02041 8.6e-148 srtB 3.4.22.70 S Sortase family
MLLIABJA_02043 1.5e-29 K Helix-turn-helix domain
MLLIABJA_02044 2.9e-17
MLLIABJA_02047 2.3e-167 D nuclear chromosome segregation
MLLIABJA_02048 2.5e-10
MLLIABJA_02049 8.7e-180 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLLIABJA_02050 8.1e-09
MLLIABJA_02052 3.3e-148 repB EP Plasmid replication protein
MLLIABJA_02055 2.5e-23
MLLIABJA_02056 2.9e-182 L Phage integrase family
MLLIABJA_02057 3.5e-154 mccF V LD-carboxypeptidase
MLLIABJA_02058 6.6e-298 O MreB/Mbl protein
MLLIABJA_02060 5.8e-146 V Psort location CytoplasmicMembrane, score
MLLIABJA_02063 6.8e-14
MLLIABJA_02064 4.7e-233 dcuS 2.7.13.3 T protein histidine kinase activity
MLLIABJA_02065 4e-243 2.7.13.3 T protein histidine kinase activity
MLLIABJA_02066 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MLLIABJA_02067 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MLLIABJA_02068 4e-125 S Protein of unknown function (DUF554)
MLLIABJA_02069 5.8e-132 ecsA_2 V abc transporter atp-binding protein
MLLIABJA_02070 2.5e-273 XK27_00765
MLLIABJA_02071 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLLIABJA_02072 2.7e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLLIABJA_02073 6.8e-55 yhaI J Membrane
MLLIABJA_02074 2.5e-80 L COG1943 Transposase and inactivated derivatives
MLLIABJA_02075 3.8e-61 yhaI J Protein of unknown function (DUF805)
MLLIABJA_02076 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLLIABJA_02077 3.4e-14 rpmH J Ribosomal protein L34
MLLIABJA_02078 4.5e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
MLLIABJA_02079 8.7e-102 K Transcriptional regulator
MLLIABJA_02080 1e-150 jag S RNA-binding protein
MLLIABJA_02081 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLLIABJA_02082 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLLIABJA_02083 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
MLLIABJA_02084 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLLIABJA_02085 6.9e-215 L Transposase IS116 IS110 IS902
MLLIABJA_02086 1.2e-141 L Integrase core domain protein
MLLIABJA_02087 8.4e-86 L transposase activity
MLLIABJA_02088 8.7e-10 S Domain of unknown function
MLLIABJA_02089 5.3e-43 S Sugar efflux transporter for intercellular exchange

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)