ORF_ID e_value Gene_name EC_number CAZy COGs Description
KKNCFHKG_00002 2e-266 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
KKNCFHKG_00003 1.9e-178 yjlA EG Putative multidrug resistance efflux transporter
KKNCFHKG_00004 8.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKNCFHKG_00005 1.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKNCFHKG_00006 3.4e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKNCFHKG_00007 1.7e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKNCFHKG_00008 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KKNCFHKG_00009 9.7e-181 kefA M Mechanosensitive ion channel
KKNCFHKG_00010 1.9e-191 S COG0491 Zn-dependent hydrolases, including glyoxylases
KKNCFHKG_00011 2.9e-09 I SCP-2 sterol transfer family
KKNCFHKG_00012 5.7e-103 S Appr-1'-p processing enzyme
KKNCFHKG_00013 7.5e-25 sspH S small acid-soluble spore protein
KKNCFHKG_00014 1.7e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKNCFHKG_00015 6.1e-185 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKNCFHKG_00016 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KKNCFHKG_00017 3.3e-141 S Sucrose-6F-phosphate phosphohydrolase
KKNCFHKG_00018 2.5e-104 yozB S membrane
KKNCFHKG_00019 9e-60
KKNCFHKG_00020 1.9e-75 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKNCFHKG_00021 8.5e-179 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
KKNCFHKG_00022 3.2e-24 kch P Ion channel
KKNCFHKG_00023 1.1e-59 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
KKNCFHKG_00024 1.1e-179 arsB 1.20.4.1 P Sodium Bile acid symporter family
KKNCFHKG_00025 1.1e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KKNCFHKG_00026 1e-75 K helix_turn_helix multiple antibiotic resistance protein
KKNCFHKG_00027 1.9e-142 S Predicted permease
KKNCFHKG_00029 6e-52 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KKNCFHKG_00030 1e-131 IQ Enoyl-(Acyl carrier protein) reductase
KKNCFHKG_00031 3.4e-214 fsr P COG0477 Permeases of the major facilitator superfamily
KKNCFHKG_00032 7.2e-74 sleB 3.5.1.28 M Cell wall
KKNCFHKG_00033 3e-147 xth 3.1.11.2 L exodeoxyribonuclease III
KKNCFHKG_00034 1.6e-26 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KKNCFHKG_00035 1.7e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KKNCFHKG_00036 1.7e-183 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KKNCFHKG_00037 1.3e-207 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KKNCFHKG_00038 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KKNCFHKG_00039 6.1e-193 G Glycosyl hydrolases family 15
KKNCFHKG_00040 7.3e-21 S YpzG-like protein
KKNCFHKG_00041 5e-82 Q protein disulfide oxidoreductase activity
KKNCFHKG_00042 3.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KKNCFHKG_00043 3.7e-119 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KKNCFHKG_00044 3.9e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KKNCFHKG_00045 2.1e-76 dps P Ferritin-like domain
KKNCFHKG_00046 1.7e-81 V VanZ like family
KKNCFHKG_00047 2.5e-167 yhcI S ABC-2 family transporter protein
KKNCFHKG_00048 1.5e-169 ydbJ V ABC transporter, ATP-binding protein
KKNCFHKG_00049 6.3e-57
KKNCFHKG_00050 1.2e-166 murB 1.3.1.98 M cell wall formation
KKNCFHKG_00051 4e-79 S Protein of unknown function (DUF1189)
KKNCFHKG_00052 6.9e-37 S Protein of unknown function (DUF1450)
KKNCFHKG_00053 5.7e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KKNCFHKG_00054 1e-55 I MaoC like domain
KKNCFHKG_00056 1.7e-198 selU S tRNA 2-selenouridine synthase
KKNCFHKG_00057 1.1e-192 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
KKNCFHKG_00058 3.9e-133 T Calcineurin-like phosphoesterase superfamily domain
KKNCFHKG_00060 3.1e-187 yraQ S Predicted permease
KKNCFHKG_00061 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KKNCFHKG_00062 1.4e-195 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKNCFHKG_00063 6.4e-73 yjlC S Protein of unknown function (DUF1641)
KKNCFHKG_00064 7.4e-222 yjlD 1.6.99.3 C NADH dehydrogenase
KKNCFHKG_00065 3.7e-229 nrnB S phosphohydrolase (DHH superfamily)
KKNCFHKG_00066 4.5e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KKNCFHKG_00067 9.7e-129 yvpB NU protein conserved in bacteria
KKNCFHKG_00068 9.2e-50 tnrA K transcriptional
KKNCFHKG_00069 4.2e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KKNCFHKG_00070 1.9e-23 S Virus attachment protein p12 family
KKNCFHKG_00071 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KKNCFHKG_00072 4.9e-37 feoA P COG1918 Fe2 transport system protein A
KKNCFHKG_00073 2e-219 dapL 2.6.1.83 E Aminotransferase
KKNCFHKG_00074 1.2e-263 argH 4.3.2.1 E argininosuccinate lyase
KKNCFHKG_00075 6.2e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KKNCFHKG_00076 3.1e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KKNCFHKG_00077 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KKNCFHKG_00078 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKNCFHKG_00079 4e-223 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KKNCFHKG_00080 1.1e-139 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KKNCFHKG_00081 4.4e-233 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KKNCFHKG_00082 4.6e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KKNCFHKG_00084 5.5e-80
KKNCFHKG_00085 1.1e-36 P catalase activity
KKNCFHKG_00086 1.6e-79
KKNCFHKG_00087 2.3e-30 cspD K Cold shock
KKNCFHKG_00089 2.3e-170 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KKNCFHKG_00090 3.9e-276 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KKNCFHKG_00091 1.7e-105 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KKNCFHKG_00092 1.3e-76 yneK S Protein of unknown function (DUF2621)
KKNCFHKG_00093 3e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KKNCFHKG_00094 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KKNCFHKG_00095 1.9e-127 ccdA O cytochrome c biogenesis protein
KKNCFHKG_00096 6.8e-28 yneF S UPF0154 protein
KKNCFHKG_00097 3.1e-72 yneE S Sporulation inhibitor of replication protein sirA
KKNCFHKG_00098 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KKNCFHKG_00099 3.4e-33 ynzC S UPF0291 protein
KKNCFHKG_00100 5.2e-116 yneB L resolvase
KKNCFHKG_00101 6.1e-52 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KKNCFHKG_00102 1.2e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKNCFHKG_00103 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
KKNCFHKG_00104 5.2e-63 glnR K transcriptional
KKNCFHKG_00105 0.0 S Dynamin family
KKNCFHKG_00106 5.5e-32
KKNCFHKG_00107 3.2e-142 f42a O prohibitin homologues
KKNCFHKG_00108 2.6e-231 pbuX F xanthine
KKNCFHKG_00109 1.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KKNCFHKG_00110 1.4e-297 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KKNCFHKG_00111 6.5e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KKNCFHKG_00112 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KKNCFHKG_00113 1.2e-97 ypsA S Belongs to the UPF0398 family
KKNCFHKG_00114 4.1e-45 cotD S Inner spore coat protein D
KKNCFHKG_00115 8.4e-251 yprB L RNase_H superfamily
KKNCFHKG_00116 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KKNCFHKG_00117 1e-75 hspX O Belongs to the small heat shock protein (HSP20) family
KKNCFHKG_00119 4.1e-65 yppG S YppG-like protein
KKNCFHKG_00120 3.6e-58 yppE S Bacterial domain of unknown function (DUF1798)
KKNCFHKG_00123 1.1e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KKNCFHKG_00124 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKNCFHKG_00125 5.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KKNCFHKG_00126 2.8e-128 dnaD L DNA replication protein DnaD
KKNCFHKG_00127 3.4e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KKNCFHKG_00128 9.5e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KKNCFHKG_00129 3.3e-77 ypmB S protein conserved in bacteria
KKNCFHKG_00130 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KKNCFHKG_00131 1.8e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KKNCFHKG_00132 2.3e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KKNCFHKG_00133 7.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KKNCFHKG_00134 3e-176 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KKNCFHKG_00135 3.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KKNCFHKG_00136 2e-214 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KKNCFHKG_00137 6.2e-131 bshB1 S proteins, LmbE homologs
KKNCFHKG_00138 7.4e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KKNCFHKG_00139 1.7e-57 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KKNCFHKG_00140 2.4e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KKNCFHKG_00141 6.8e-81 queT S QueT transporter
KKNCFHKG_00142 3.4e-102 yugP S Zn-dependent protease
KKNCFHKG_00143 6e-143 ypjB S sporulation protein
KKNCFHKG_00144 2.5e-109 ypjA S membrane
KKNCFHKG_00145 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KKNCFHKG_00146 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
KKNCFHKG_00147 1.9e-97 qcrA C Menaquinol-cytochrome c reductase
KKNCFHKG_00148 1.9e-80 ypiF S Protein of unknown function (DUF2487)
KKNCFHKG_00149 5.9e-97 ypiB S Belongs to the UPF0302 family
KKNCFHKG_00150 1.2e-238 S COG0457 FOG TPR repeat
KKNCFHKG_00151 2.5e-231 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KKNCFHKG_00152 1.2e-202 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KKNCFHKG_00153 7.9e-210 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKNCFHKG_00154 3.8e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KKNCFHKG_00155 4.4e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KKNCFHKG_00156 1.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KKNCFHKG_00157 2.4e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KKNCFHKG_00158 7.2e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KKNCFHKG_00159 4.1e-170 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKNCFHKG_00160 6.4e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KKNCFHKG_00161 3.3e-144 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KKNCFHKG_00162 1.9e-33 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KKNCFHKG_00163 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KKNCFHKG_00164 8.3e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KKNCFHKG_00165 1.7e-136 yphF
KKNCFHKG_00166 3.2e-08 yphE S Protein of unknown function (DUF2768)
KKNCFHKG_00167 4.6e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KKNCFHKG_00168 5.5e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KKNCFHKG_00169 2.4e-19 yphA
KKNCFHKG_00170 7.3e-14 S YpzI-like protein
KKNCFHKG_00171 9.4e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KKNCFHKG_00172 1.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KKNCFHKG_00173 2.3e-116 ypfA M Flagellar protein YcgR
KKNCFHKG_00174 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KKNCFHKG_00175 2.6e-146 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KKNCFHKG_00176 7e-124 prsW S Involved in the degradation of specific anti-sigma factors
KKNCFHKG_00177 5.1e-184 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KKNCFHKG_00178 4.4e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KKNCFHKG_00179 3.8e-96 mecB NOT Negative regulator of genetic competence (MecA)
KKNCFHKG_00180 1.8e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
KKNCFHKG_00181 2.6e-30 cotJA S Spore coat associated protein JA (CotJA)
KKNCFHKG_00182 1.2e-44 cotJB S CotJB protein
KKNCFHKG_00183 1.5e-103 cotJC P Spore Coat
KKNCFHKG_00184 1.2e-79 ypbF S Protein of unknown function (DUF2663)
KKNCFHKG_00186 1.2e-100 ypbD S metal-dependent membrane protease
KKNCFHKG_00187 5.4e-278 recQ 3.6.4.12 L DNA helicase
KKNCFHKG_00188 1.1e-203 ypbB 5.1.3.1 S protein conserved in bacteria
KKNCFHKG_00189 7.8e-41 fer C Ferredoxin
KKNCFHKG_00190 2.4e-96 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KKNCFHKG_00191 3.2e-127 M COG0739 Membrane proteins related to metalloendopeptidases
KKNCFHKG_00192 0.0 resE 2.7.13.3 T Histidine kinase
KKNCFHKG_00193 3.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_00194 2.2e-229 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KKNCFHKG_00195 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KKNCFHKG_00196 2.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KKNCFHKG_00197 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKNCFHKG_00198 1.4e-87 spmB S Spore maturation protein
KKNCFHKG_00199 5.2e-96 spmA S Spore maturation protein
KKNCFHKG_00200 3.6e-202 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KKNCFHKG_00201 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKNCFHKG_00202 1.7e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KKNCFHKG_00204 2.2e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKNCFHKG_00205 1.6e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KKNCFHKG_00206 5e-268 spoVAF EG Stage V sporulation protein AF
KKNCFHKG_00207 8e-105 spoVAEA S Stage V sporulation protein AE
KKNCFHKG_00208 4.6e-65 spoVAB S Stage V sporulation protein AB
KKNCFHKG_00209 6.5e-108 spoVAA S Stage V sporulation protein AA
KKNCFHKG_00210 1.4e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_00211 8.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KKNCFHKG_00212 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KKNCFHKG_00213 7.6e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KKNCFHKG_00215 3.6e-168 xerD L recombinase XerD
KKNCFHKG_00216 3.7e-34 S Protein of unknown function (DUF4227)
KKNCFHKG_00217 3.5e-85 fur P Belongs to the Fur family
KKNCFHKG_00218 1.5e-104 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KKNCFHKG_00219 1.1e-228 yqxK 3.6.4.12 L DNA helicase
KKNCFHKG_00220 1.6e-97 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KKNCFHKG_00222 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KKNCFHKG_00223 1e-08 S Protein of unknown function (DUF3886)
KKNCFHKG_00224 5.6e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KKNCFHKG_00225 1.3e-213 yaaN P Belongs to the TelA family
KKNCFHKG_00226 8.2e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KKNCFHKG_00227 2.4e-235 yaaH_2 M Glycoside Hydrolase Family
KKNCFHKG_00228 6.6e-54 S YolD-like protein
KKNCFHKG_00229 1.3e-240 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKNCFHKG_00230 1.1e-144 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KKNCFHKG_00231 2.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKNCFHKG_00232 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KKNCFHKG_00233 6.4e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KKNCFHKG_00234 8.7e-226 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKNCFHKG_00235 2.9e-76 cheW NT COG0835 Chemotaxis signal transduction protein
KKNCFHKG_00236 2.1e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KKNCFHKG_00237 3.6e-93 yqjB S protein conserved in bacteria
KKNCFHKG_00238 2.1e-76 yqiW S Belongs to the UPF0403 family
KKNCFHKG_00239 3.4e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KKNCFHKG_00240 3e-216 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKNCFHKG_00241 3.9e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKNCFHKG_00242 5e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKNCFHKG_00243 4.4e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKNCFHKG_00244 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KKNCFHKG_00245 4.4e-18 T transcription factor binding
KKNCFHKG_00246 9.2e-66 bkdR 2.7.13.3 KT Transcriptional regulator
KKNCFHKG_00247 9.8e-36 yqzF S Protein of unknown function (DUF2627)
KKNCFHKG_00248 1e-131 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKNCFHKG_00249 4.4e-138 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KKNCFHKG_00250 3.5e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
KKNCFHKG_00251 9.5e-295 recN L May be involved in recombinational repair of damaged DNA
KKNCFHKG_00252 5.4e-80 argR K Regulates arginine biosynthesis genes
KKNCFHKG_00253 8.5e-148 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KKNCFHKG_00254 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKNCFHKG_00255 7.5e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKNCFHKG_00256 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKNCFHKG_00257 3.5e-228 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKNCFHKG_00258 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKNCFHKG_00259 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKNCFHKG_00260 1.1e-68 yqhY S protein conserved in bacteria
KKNCFHKG_00261 6.2e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KKNCFHKG_00262 6.8e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KKNCFHKG_00263 5.5e-79 spoIIIAH S SpoIIIAH-like protein
KKNCFHKG_00264 6.6e-111 spoIIIAG S stage III sporulation protein AG
KKNCFHKG_00265 1.8e-105 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KKNCFHKG_00266 1.2e-174 spoIIIAE S stage III sporulation protein AE
KKNCFHKG_00267 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KKNCFHKG_00268 1.4e-27 spoIIIAC S stage III sporulation protein AC
KKNCFHKG_00269 3.7e-85 spoIIIAB S Stage III sporulation protein
KKNCFHKG_00270 2.1e-171 spoIIIAA S stage III sporulation protein AA
KKNCFHKG_00271 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKNCFHKG_00272 9.2e-155 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KKNCFHKG_00273 2.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KKNCFHKG_00274 8.7e-90 yqhR S Conserved membrane protein YqhR
KKNCFHKG_00275 8e-163 yqhQ S Protein of unknown function (DUF1385)
KKNCFHKG_00276 4.3e-11 yqhP
KKNCFHKG_00277 4.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
KKNCFHKG_00278 2.3e-71 bktB 2.3.1.9 I Belongs to the thiolase family
KKNCFHKG_00279 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
KKNCFHKG_00280 6.8e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KKNCFHKG_00281 2.2e-66 yqhL P COG0607 Rhodanese-related sulfurtransferase
KKNCFHKG_00282 1.8e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKNCFHKG_00283 5.3e-256 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKNCFHKG_00284 1.2e-213 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KKNCFHKG_00285 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KKNCFHKG_00286 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
KKNCFHKG_00287 1.1e-09 yqzE S YqzE-like protein
KKNCFHKG_00288 5.4e-98 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KKNCFHKG_00289 4e-57 S ComG operon protein 7
KKNCFHKG_00290 4.9e-79 comGF U COG4940 Competence protein ComGF
KKNCFHKG_00292 9.7e-74 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
KKNCFHKG_00293 9.9e-49 comGC U Required for transformation and DNA binding
KKNCFHKG_00294 8.3e-171 comGB NU COG1459 Type II secretory pathway, component PulF
KKNCFHKG_00295 1.1e-203 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KKNCFHKG_00296 1e-128 K Helix-turn-helix domain
KKNCFHKG_00297 5.7e-36 yqgY S Protein of unknown function (DUF2626)
KKNCFHKG_00298 5e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KKNCFHKG_00299 2.9e-21 yqgW S Protein of unknown function (DUF2759)
KKNCFHKG_00300 1.6e-169 glcK 2.7.1.2 G Glucokinase
KKNCFHKG_00301 2.8e-29 yqgQ S protein conserved in bacteria
KKNCFHKG_00302 5.4e-201 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KKNCFHKG_00304 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KKNCFHKG_00305 9.8e-56 yqzD
KKNCFHKG_00306 0.0 mrdA 3.4.16.4 M penicillin-binding protein
KKNCFHKG_00307 1.2e-219 yqgE EGP Major facilitator superfamily
KKNCFHKG_00308 3.7e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KKNCFHKG_00309 3.4e-55 fimV NU Tfp pilus assembly protein FimV
KKNCFHKG_00310 6.8e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KKNCFHKG_00311 4.4e-114 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KKNCFHKG_00312 2.2e-75 zur P Belongs to the Fur family
KKNCFHKG_00313 4e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KKNCFHKG_00314 3.2e-141 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KKNCFHKG_00315 1e-19 yqfT S Protein of unknown function (DUF2624)
KKNCFHKG_00316 3.4e-125 cwlO CBM50 M protein conserved in bacteria
KKNCFHKG_00317 1.1e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KKNCFHKG_00318 7.2e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KKNCFHKG_00320 1.5e-133 modA P Molybdenum ABC transporter
KKNCFHKG_00321 1e-120 P COG4149 ABC-type molybdate transport system, permease component
KKNCFHKG_00322 1.5e-129 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
KKNCFHKG_00323 7.8e-188 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KKNCFHKG_00324 1.4e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KKNCFHKG_00325 7.8e-123 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KKNCFHKG_00326 3.7e-235 moeA 2.10.1.1 H molybdopterin
KKNCFHKG_00327 1.9e-86 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KKNCFHKG_00328 1.2e-79 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KKNCFHKG_00329 1.1e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KKNCFHKG_00330 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KKNCFHKG_00331 4e-192 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KKNCFHKG_00332 5.7e-89 yrhD S Protein of unknown function (DUF1641)
KKNCFHKG_00333 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KKNCFHKG_00334 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KKNCFHKG_00335 3.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKNCFHKG_00336 1.7e-254 prdR KT Transcriptional regulator
KKNCFHKG_00337 3.7e-298 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KKNCFHKG_00338 4e-184 putA E Proline dehydrogenase
KKNCFHKG_00339 2e-126
KKNCFHKG_00340 1.3e-145
KKNCFHKG_00341 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KKNCFHKG_00342 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KKNCFHKG_00343 5.4e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KKNCFHKG_00344 4.6e-117 yttP K Transcriptional regulator
KKNCFHKG_00345 3.4e-308 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KKNCFHKG_00346 2.8e-213 iscS2 2.8.1.7 E Cysteine desulfurase
KKNCFHKG_00347 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKNCFHKG_00348 1.4e-27 sspB S spore protein
KKNCFHKG_00349 2.2e-311 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KKNCFHKG_00350 6.7e-179 sppA OU signal peptide peptidase SppA
KKNCFHKG_00351 4.2e-84 yteJ S RDD family
KKNCFHKG_00352 2e-118 ytfI S Protein of unknown function (DUF2953)
KKNCFHKG_00353 2e-66 ytfJ S Sporulation protein YtfJ
KKNCFHKG_00354 2.2e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KKNCFHKG_00355 2.4e-176 ytxK 2.1.1.72 L DNA methylase
KKNCFHKG_00356 3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKNCFHKG_00357 2.7e-149 S EcsC protein family
KKNCFHKG_00358 3.1e-78 uspA T Belongs to the universal stress protein A family
KKNCFHKG_00359 1.3e-196 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KKNCFHKG_00360 1.6e-178 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KKNCFHKG_00361 1.1e-129 ytkL S Belongs to the UPF0173 family
KKNCFHKG_00362 2.3e-240 ytoI K transcriptional regulator containing CBS domains
KKNCFHKG_00363 2.7e-38 ytpI S YtpI-like protein
KKNCFHKG_00364 3.5e-175 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KKNCFHKG_00365 6.7e-87 ytrI
KKNCFHKG_00366 1.6e-41 ytrH S Sporulation protein YtrH
KKNCFHKG_00367 0.0 dnaE 2.7.7.7 L DNA polymerase
KKNCFHKG_00368 6.8e-226 ytsJ 1.1.1.38 C Malate dehydrogenase
KKNCFHKG_00369 2.4e-164 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KKNCFHKG_00370 1e-176 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KKNCFHKG_00371 2.7e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KKNCFHKG_00372 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KKNCFHKG_00373 1e-156 ytvI S sporulation integral membrane protein YtvI
KKNCFHKG_00374 1e-73 yeaL S Membrane
KKNCFHKG_00375 4.1e-206 citZ 2.3.3.1 C Belongs to the citrate synthase family
KKNCFHKG_00376 4e-245 icd 1.1.1.42 C isocitrate
KKNCFHKG_00377 2.9e-168 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KKNCFHKG_00378 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKNCFHKG_00379 8.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KKNCFHKG_00380 1.3e-106 ytaF P Probably functions as a manganese efflux pump
KKNCFHKG_00381 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKNCFHKG_00382 3.5e-191 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KKNCFHKG_00383 3.2e-86 2.3.1.178 J Benzoate transporter
KKNCFHKG_00384 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKNCFHKG_00385 2.1e-260 dnaB L Membrane attachment protein
KKNCFHKG_00386 8.4e-176 dnaI L Primosomal protein DnaI
KKNCFHKG_00387 2.4e-150 ytxC S YtxC-like family
KKNCFHKG_00388 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKNCFHKG_00389 7.1e-71 G Transmembrane secretion effector
KKNCFHKG_00390 5.1e-108 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKNCFHKG_00391 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KKNCFHKG_00392 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKNCFHKG_00394 3.3e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KKNCFHKG_00395 1.2e-96 ypdE 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKNCFHKG_00396 2.3e-101 yieF S NAD(P)H-dependent FMN reductase
KKNCFHKG_00397 2.2e-176 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KKNCFHKG_00398 1.1e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KKNCFHKG_00399 4e-11 S NADPH-dependent FMN reductase
KKNCFHKG_00400 1.8e-56 K Transcriptional regulator
KKNCFHKG_00401 6.3e-120 M1-1017 S Protein of unknown function (DUF1129)
KKNCFHKG_00402 1.2e-29 sidE D nuclear chromosome segregation
KKNCFHKG_00403 8.9e-136
KKNCFHKG_00404 8.3e-31 sspI S Belongs to the SspI family
KKNCFHKG_00405 1.5e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKNCFHKG_00406 9.6e-181 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKNCFHKG_00407 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKNCFHKG_00408 1.4e-86 V Mate efflux family protein
KKNCFHKG_00409 5.5e-45 KT Transcriptional
KKNCFHKG_00410 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKNCFHKG_00411 1.6e-42 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KKNCFHKG_00412 1.4e-87 cvpA S membrane protein, required for colicin V production
KKNCFHKG_00413 0.0 polX L COG1796 DNA polymerase IV (family X)
KKNCFHKG_00414 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KKNCFHKG_00415 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKNCFHKG_00416 6.6e-102 fadR K Transcriptional regulator
KKNCFHKG_00417 4.4e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KKNCFHKG_00418 4.8e-129 etfB C Electron transfer flavoprotein
KKNCFHKG_00419 6.9e-173 etfA C Electron transfer flavoprotein
KKNCFHKG_00420 5.1e-53 trxA O Belongs to the thioredoxin family
KKNCFHKG_00421 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KKNCFHKG_00422 2e-222 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KKNCFHKG_00423 7.9e-79 yslB S Protein of unknown function (DUF2507)
KKNCFHKG_00424 2.5e-104 sdhC C succinate dehydrogenase
KKNCFHKG_00425 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KKNCFHKG_00426 6.5e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KKNCFHKG_00427 6.7e-89 ysmA S thioesterase
KKNCFHKG_00428 2.3e-31 gerE K Transcriptional regulator
KKNCFHKG_00430 3.2e-187 S Predicted membrane protein (DUF2157)
KKNCFHKG_00431 2.9e-85 S GDYXXLXY protein
KKNCFHKG_00432 3.9e-78 ysmB 2.4.2.28 K transcriptional
KKNCFHKG_00433 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KKNCFHKG_00435 1.5e-189 gerM S COG5401 Spore germination protein
KKNCFHKG_00436 6.6e-105 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KKNCFHKG_00437 7e-92 ysnB S Phosphoesterase
KKNCFHKG_00439 1.5e-46
KKNCFHKG_00440 5.9e-71 S Protein of unknown function (DUF2512)
KKNCFHKG_00441 6.8e-184 trxA2 O COG0457 FOG TPR repeat
KKNCFHKG_00442 1.2e-209 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KKNCFHKG_00443 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KKNCFHKG_00444 5.9e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KKNCFHKG_00445 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KKNCFHKG_00446 1.3e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
KKNCFHKG_00447 2.2e-87 ysxD
KKNCFHKG_00448 2.1e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KKNCFHKG_00449 1.7e-148 hemX O cytochrome C
KKNCFHKG_00450 4.6e-166 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KKNCFHKG_00451 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KKNCFHKG_00452 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
KKNCFHKG_00453 3.5e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KKNCFHKG_00454 7.4e-192 spoVID M stage VI sporulation protein D
KKNCFHKG_00455 7.6e-191 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KKNCFHKG_00456 3.3e-26
KKNCFHKG_00457 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KKNCFHKG_00458 3.6e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KKNCFHKG_00460 6.7e-87
KKNCFHKG_00461 1.1e-223 NU Pilus assembly protein PilX
KKNCFHKG_00462 3.7e-188
KKNCFHKG_00463 3.9e-128 S PRC-barrel domain
KKNCFHKG_00464 2.3e-217 V G5
KKNCFHKG_00465 1.2e-294 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KKNCFHKG_00466 2.6e-194 pilT NU twitching motility protein
KKNCFHKG_00467 2.3e-202 pilC NU type II secretion system
KKNCFHKG_00468 4.6e-52 NU cell adhesion
KKNCFHKG_00469 5.6e-186 NU COG4972 Tfp pilus assembly protein, ATPase PilM
KKNCFHKG_00470 7.3e-86 pilN NU PFAM Fimbrial assembly family protein
KKNCFHKG_00471 4.2e-103
KKNCFHKG_00472 4.2e-133 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KKNCFHKG_00473 1.7e-171 spoIIB
KKNCFHKG_00474 1.1e-121 radC E Belongs to the UPF0758 family
KKNCFHKG_00475 6.9e-184 mreB D Rod shape-determining protein MreB
KKNCFHKG_00476 4.4e-139 mreC M Involved in formation and maintenance of cell shape
KKNCFHKG_00477 2.4e-87 mreD M shape-determining protein
KKNCFHKG_00478 8.8e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KKNCFHKG_00479 1e-145 minD D Belongs to the ParA family
KKNCFHKG_00480 1.5e-135 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KKNCFHKG_00481 9.8e-163 spoIVFB S Stage IV sporulation protein
KKNCFHKG_00482 2.9e-279 rng J ribonuclease, Rne Rng family
KKNCFHKG_00483 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KKNCFHKG_00484 1.6e-52 ysxB J ribosomal protein
KKNCFHKG_00485 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KKNCFHKG_00486 3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KKNCFHKG_00487 9.9e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKNCFHKG_00488 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
KKNCFHKG_00489 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
KKNCFHKG_00490 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
KKNCFHKG_00491 4.3e-143 safA M spore coat assembly protein SafA
KKNCFHKG_00492 3.1e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
KKNCFHKG_00493 1.7e-128 yebC K transcriptional regulatory protein
KKNCFHKG_00494 1.7e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KKNCFHKG_00495 2e-183 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KKNCFHKG_00496 5.4e-27 yrzS S Protein of unknown function (DUF2905)
KKNCFHKG_00497 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KKNCFHKG_00498 6.9e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KKNCFHKG_00499 1.2e-44 yajC U Preprotein translocase subunit YajC
KKNCFHKG_00500 4.9e-61 yrzE S Protein of unknown function (DUF3792)
KKNCFHKG_00501 6e-104 yrbG S membrane
KKNCFHKG_00502 1.9e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKNCFHKG_00503 3.6e-60 yrzD S Post-transcriptional regulator
KKNCFHKG_00504 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKNCFHKG_00505 6e-174 spoVK O stage V sporulation protein K
KKNCFHKG_00506 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KKNCFHKG_00507 6.1e-246 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KKNCFHKG_00508 4.6e-171 polA 2.7.7.7 L 5'3' exonuclease
KKNCFHKG_00509 3.6e-27 ypeQ S Zinc-finger
KKNCFHKG_00511 1.2e-31 cspD K Cold-shock protein
KKNCFHKG_00512 3e-72 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KKNCFHKG_00513 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KKNCFHKG_00514 7.3e-86
KKNCFHKG_00515 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KKNCFHKG_00516 7e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
KKNCFHKG_00517 2.3e-75 yphP S Belongs to the UPF0403 family
KKNCFHKG_00518 8.7e-107 ypjP S YpjP-like protein
KKNCFHKG_00519 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKNCFHKG_00520 1.2e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KKNCFHKG_00521 2.9e-111 hlyIII S protein, Hemolysin III
KKNCFHKG_00522 3.4e-146 ypmR E COG2755 Lysophospholipase L1 and related esterases
KKNCFHKG_00523 9.3e-98 ypmS S protein conserved in bacteria
KKNCFHKG_00524 2.3e-275 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
KKNCFHKG_00525 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKNCFHKG_00526 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KKNCFHKG_00527 1.2e-09 S Protein of unknown function (Tiny_TM_bacill)
KKNCFHKG_00528 8.5e-193 NT CHASE3 domain
KKNCFHKG_00529 5.7e-35 yozE S Belongs to the UPF0346 family
KKNCFHKG_00530 2.1e-114 yodN
KKNCFHKG_00531 7.5e-25 yozD S YozD-like protein
KKNCFHKG_00532 2e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KKNCFHKG_00533 3.7e-271 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KKNCFHKG_00534 6.1e-65 ypoP K transcriptional
KKNCFHKG_00536 2.9e-99 ykwD J protein with SCP PR1 domains
KKNCFHKG_00537 3.5e-239 norM V Multidrug efflux pump
KKNCFHKG_00539 3.3e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KKNCFHKG_00540 8.9e-72 ligD 6.5.1.1 L ATP-dependent DNA ligase
KKNCFHKG_00541 1.3e-132 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KKNCFHKG_00542 2.2e-111 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KKNCFHKG_00543 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KKNCFHKG_00544 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KKNCFHKG_00545 3.6e-222 ymfD EGP Major facilitator Superfamily
KKNCFHKG_00546 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_00547 2.4e-251 arlS 2.7.13.3 T Histidine kinase
KKNCFHKG_00548 7.5e-74 yozR S COG0071 Molecular chaperone (small heat shock protein)
KKNCFHKG_00549 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KKNCFHKG_00550 4.4e-204 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KKNCFHKG_00551 5.4e-228 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KKNCFHKG_00552 1.8e-80 rok S Repressor of ComK
KKNCFHKG_00553 5.2e-115 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKNCFHKG_00555 7.2e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KKNCFHKG_00556 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKNCFHKG_00557 7.8e-193 yceA S Belongs to the UPF0176 family
KKNCFHKG_00558 1.1e-129 yoqW S Belongs to the SOS response-associated peptidase family
KKNCFHKG_00559 1.1e-104 thiT S Proton-coupled thiamine transporter YuaJ
KKNCFHKG_00560 7.6e-168 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KKNCFHKG_00561 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
KKNCFHKG_00562 4.3e-116 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KKNCFHKG_00563 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
KKNCFHKG_00564 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKNCFHKG_00565 4e-243 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KKNCFHKG_00566 3.8e-148 corA P Mg2 transporter protein
KKNCFHKG_00567 7.1e-64 S CHY zinc finger
KKNCFHKG_00568 6.2e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KKNCFHKG_00569 1.8e-110 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KKNCFHKG_00570 5.1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KKNCFHKG_00571 2.9e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KKNCFHKG_00572 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KKNCFHKG_00573 1.4e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KKNCFHKG_00574 1.3e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KKNCFHKG_00575 3.1e-116 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KKNCFHKG_00576 1.1e-39 yedF O Belongs to the sulfur carrier protein TusA family
KKNCFHKG_00577 1.8e-239 yedE S Sulphur transport
KKNCFHKG_00578 6.1e-161 rarD S -transporter
KKNCFHKG_00579 6.5e-219 ktrB P COG0168 Trk-type K transport systems, membrane components
KKNCFHKG_00580 1.9e-121 P COG0569 K transport systems, NAD-binding component
KKNCFHKG_00581 8.3e-134 ykrK S Domain of unknown function (DUF1836)
KKNCFHKG_00582 4.6e-15
KKNCFHKG_00583 1.1e-44 yxcD S Protein of unknown function (DUF2653)
KKNCFHKG_00584 5.2e-215 yeaN P COG2807 Cyanate permease
KKNCFHKG_00585 2.1e-310 ubiB S ABC1 family
KKNCFHKG_00586 4.7e-24 S ATP synthase, subunit b
KKNCFHKG_00587 7.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKNCFHKG_00589 2.7e-31 cspB K Cold shock
KKNCFHKG_00590 3.2e-118 folE 3.5.4.16 H GTP cyclohydrolase
KKNCFHKG_00591 1e-173 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
KKNCFHKG_00592 2.8e-45 S Protein of unknown function (DUF1292)
KKNCFHKG_00593 5.2e-47 yxiS
KKNCFHKG_00594 0.0 bceB V ABC transporter (permease)
KKNCFHKG_00595 1.2e-135 bceA V ABC transporter, ATP-binding protein
KKNCFHKG_00596 2e-183 bceS 2.7.13.3 T Signal transduction histidine kinase
KKNCFHKG_00597 1.6e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_00598 6.7e-230 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KKNCFHKG_00599 3.2e-190 yetN S Protein of unknown function (DUF3900)
KKNCFHKG_00600 3.1e-232 ywoD EGP Major facilitator superfamily
KKNCFHKG_00601 5.9e-49 iscA S Heme biosynthesis protein HemY
KKNCFHKG_00602 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKNCFHKG_00603 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKNCFHKG_00604 9.4e-43 S Small, acid-soluble spore proteins, alpha/beta type
KKNCFHKG_00605 6.4e-61 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KKNCFHKG_00606 2e-110 M effector of murein hydrolase
KKNCFHKG_00607 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKNCFHKG_00608 4.4e-109 M lytic transglycosylase activity
KKNCFHKG_00609 1.1e-08 S membrane
KKNCFHKG_00610 8.6e-19 sspP S Belongs to the SspP family
KKNCFHKG_00611 4.5e-39
KKNCFHKG_00612 7.1e-239 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KKNCFHKG_00613 4.4e-18 sspO S Belongs to the SspO family
KKNCFHKG_00614 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KKNCFHKG_00616 4.1e-31 tlp S Belongs to the Tlp family
KKNCFHKG_00617 2.2e-75 yneP S thioesterase
KKNCFHKG_00618 5.5e-52 yneQ
KKNCFHKG_00619 5.3e-52 yneR S Belongs to the HesB IscA family
KKNCFHKG_00620 5e-97 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KKNCFHKG_00621 7.2e-71 yccU S CoA-binding protein
KKNCFHKG_00622 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKNCFHKG_00623 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKNCFHKG_00624 6.3e-145
KKNCFHKG_00625 7.1e-215 yjjL G Major facilitator superfamily
KKNCFHKG_00626 7.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KKNCFHKG_00627 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KKNCFHKG_00630 3.1e-198 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KKNCFHKG_00633 3.6e-102 5.1.3.34 S oxidoreductase activity
KKNCFHKG_00634 9.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KKNCFHKG_00636 2.6e-197 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
KKNCFHKG_00637 2.7e-162 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KKNCFHKG_00638 2.1e-08
KKNCFHKG_00641 1e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KKNCFHKG_00642 9.1e-81 yvbK 3.1.3.25 K acetyltransferase
KKNCFHKG_00643 2.5e-74 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
KKNCFHKG_00644 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
KKNCFHKG_00645 3e-121 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KKNCFHKG_00646 2.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKNCFHKG_00647 2.6e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KKNCFHKG_00648 3.3e-08 ykyB S YkyB-like protein
KKNCFHKG_00649 5.2e-124 yflK S protein conserved in bacteria
KKNCFHKG_00650 9.9e-10 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KKNCFHKG_00651 4.9e-246 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KKNCFHKG_00652 4.8e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KKNCFHKG_00653 1.8e-80 K Acetyltransferase (GNAT) domain
KKNCFHKG_00654 4.7e-97 O HI0933-like protein
KKNCFHKG_00655 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKNCFHKG_00656 0.0 yjcD 3.6.4.12 L DNA helicase
KKNCFHKG_00657 1.6e-225 ywdJ F Xanthine uracil
KKNCFHKG_00658 3.1e-165 ytnM S membrane transporter protein
KKNCFHKG_00659 1.6e-236 E COG1113 Gamma-aminobutyrate permease and related permeases
KKNCFHKG_00660 3.6e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KKNCFHKG_00661 0.0 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KKNCFHKG_00662 6.3e-190 amiE 3.5.1.4 S Carbon-nitrogen hydrolase
KKNCFHKG_00663 6.9e-309 F COG1457 Purine-cytosine permease and related proteins
KKNCFHKG_00664 1.8e-200 amiF 3.5.1.49 S Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide
KKNCFHKG_00665 3.7e-48 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KKNCFHKG_00666 6.7e-56 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KKNCFHKG_00667 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KKNCFHKG_00668 6e-79 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KKNCFHKG_00669 1.6e-104 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KKNCFHKG_00670 7.3e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KKNCFHKG_00671 2e-157 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KKNCFHKG_00672 6.1e-112 ureH S PFAM Nickel cobalt transporter, high-affinity
KKNCFHKG_00673 1.8e-171 pfoS S Phosphotransferase system, EIIC
KKNCFHKG_00674 2.3e-184 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
KKNCFHKG_00675 3.6e-100 dhaL 2.7.1.121 S Dak2
KKNCFHKG_00676 2.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
KKNCFHKG_00677 3.5e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKNCFHKG_00678 1.6e-123 ywaC 2.7.6.5 S protein conserved in bacteria
KKNCFHKG_00679 1.3e-70 ywnF S Family of unknown function (DUF5392)
KKNCFHKG_00681 2.2e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KKNCFHKG_00682 4.7e-253 iolT EGP Major facilitator Superfamily
KKNCFHKG_00683 7.8e-85 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KKNCFHKG_00684 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
KKNCFHKG_00685 2.5e-152 yidA S hydrolases of the HAD superfamily
KKNCFHKG_00686 8.2e-32
KKNCFHKG_00687 1.1e-22 D Hemerythrin HHE cation binding
KKNCFHKG_00688 1.8e-47 D Hemerythrin HHE cation binding
KKNCFHKG_00689 3.2e-203 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KKNCFHKG_00690 1.3e-131 fruR K Transcriptional regulator
KKNCFHKG_00691 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KKNCFHKG_00692 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KKNCFHKG_00693 6e-35 yoeD G Helix-turn-helix domain
KKNCFHKG_00694 5.7e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KKNCFHKG_00695 1.7e-207 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KKNCFHKG_00697 2e-88 1.8.5.2 S DoxX
KKNCFHKG_00698 8e-108 C Nitroreductase family
KKNCFHKG_00699 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KKNCFHKG_00700 1.6e-126 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
KKNCFHKG_00701 0.0 csh
KKNCFHKG_00702 1.2e-177 L CRISPR-associated protein Cas7
KKNCFHKG_00703 3e-144 cas5h S CRISPR-associated protein Cas5
KKNCFHKG_00704 0.0 cas3 L CRISPR-associated helicase, Cas3
KKNCFHKG_00705 1.1e-70 cas4 3.1.12.1 L Domain of unknown function DUF83
KKNCFHKG_00706 7e-189 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KKNCFHKG_00707 1.1e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KKNCFHKG_00708 5.1e-219 L Transposase DDE domain group 1
KKNCFHKG_00709 2.3e-72 K sequence-specific DNA binding
KKNCFHKG_00710 2e-117 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
KKNCFHKG_00711 2.1e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKNCFHKG_00712 9.4e-222 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KKNCFHKG_00713 1.4e-150 K RpiR family transcriptional regulator
KKNCFHKG_00714 7.4e-161 ypuA S Secreted protein
KKNCFHKG_00715 9.7e-113
KKNCFHKG_00716 3.1e-69 S response to pH
KKNCFHKG_00717 3.8e-105 che
KKNCFHKG_00718 2.8e-293 K helix_turn_helix, Lux Regulon
KKNCFHKG_00721 2e-89 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKNCFHKG_00722 1.1e-21 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKNCFHKG_00723 2.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
KKNCFHKG_00724 1.8e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KKNCFHKG_00725 6.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KKNCFHKG_00726 9.7e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KKNCFHKG_00727 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKNCFHKG_00728 6.7e-88 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KKNCFHKG_00729 5.5e-169 yuaG S protein conserved in bacteria
KKNCFHKG_00730 1.7e-182 mreB D Rod-share determining protein MreBH
KKNCFHKG_00731 1.3e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KKNCFHKG_00732 2.5e-146 dksA T COG1734 DnaK suppressor protein
KKNCFHKG_00733 8.2e-227 EGP Major facilitator Superfamily
KKNCFHKG_00734 3.7e-60 yeaO S Protein of unknown function, DUF488
KKNCFHKG_00736 1.3e-57 yhdN S Domain of unknown function (DUF1992)
KKNCFHKG_00737 6.6e-137 motA N flagellar motor
KKNCFHKG_00738 1.9e-139 motB N Flagellar motor protein
KKNCFHKG_00739 3.5e-91 yfkM 3.5.1.124 S protease
KKNCFHKG_00740 3.4e-143 map 3.4.11.18 E Methionine aminopeptidase
KKNCFHKG_00741 7.3e-33 yfkK S Belongs to the UPF0435 family
KKNCFHKG_00742 1.1e-147 yihY S Belongs to the UPF0761 family
KKNCFHKG_00743 1e-218 yfkF EGP Major facilitator Superfamily
KKNCFHKG_00744 2.9e-172 cax P COG0387 Ca2 H antiporter
KKNCFHKG_00745 9e-147 yfkD S YfkD-like protein
KKNCFHKG_00746 1.5e-26 yfjT
KKNCFHKG_00747 1.3e-148 pdaA G deacetylase
KKNCFHKG_00748 8.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KKNCFHKG_00749 1.1e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKNCFHKG_00750 2.8e-100 K DNA-binding transcription factor activity
KKNCFHKG_00751 5.6e-298 lmrA 3.6.3.44 V ABC transporter
KKNCFHKG_00753 4.5e-120 L Transposase IS4 family protein
KKNCFHKG_00754 1.1e-291 mqo 1.1.5.4 S malate quinone oxidoreductase
KKNCFHKG_00755 3.4e-115 papP E amino acid ABC transporter
KKNCFHKG_00756 1.4e-103 E amino acid ABC transporter
KKNCFHKG_00757 1.6e-129 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
KKNCFHKG_00758 6.2e-138 cjaA ET Belongs to the bacterial solute-binding protein 3 family
KKNCFHKG_00759 8.7e-215 5.1.1.12 E Alanine racemase, N-terminal domain
KKNCFHKG_00760 8.1e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
KKNCFHKG_00761 4.9e-223 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
KKNCFHKG_00762 8.9e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
KKNCFHKG_00763 8.6e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KKNCFHKG_00764 2.5e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_00765 1.9e-59 asp S protein conserved in bacteria
KKNCFHKG_00766 6.7e-301 yloV S kinase related to dihydroxyacetone kinase
KKNCFHKG_00767 1.3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
KKNCFHKG_00768 3.5e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KKNCFHKG_00769 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KKNCFHKG_00770 8.8e-99 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KKNCFHKG_00771 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KKNCFHKG_00772 4.2e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKNCFHKG_00773 2.1e-129 IQ reductase
KKNCFHKG_00774 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKNCFHKG_00775 1.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KKNCFHKG_00776 0.0 smc D Required for chromosome condensation and partitioning
KKNCFHKG_00777 1.3e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KKNCFHKG_00778 2.9e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KKNCFHKG_00779 8.7e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KKNCFHKG_00780 1.7e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KKNCFHKG_00781 5.5e-36 ylqC S Belongs to the UPF0109 family
KKNCFHKG_00782 7.1e-60 ylqD S YlqD protein
KKNCFHKG_00783 4.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KKNCFHKG_00784 2e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KKNCFHKG_00785 2.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KKNCFHKG_00786 1.2e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KKNCFHKG_00787 4.7e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KKNCFHKG_00788 1.7e-129 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKNCFHKG_00789 2.8e-227 CP_1081 D nuclear chromosome segregation
KKNCFHKG_00790 3.1e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KKNCFHKG_00791 1.6e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KKNCFHKG_00792 1.7e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KKNCFHKG_00793 4.6e-160 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KKNCFHKG_00794 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKNCFHKG_00795 4.3e-169 xerC L tyrosine recombinase XerC
KKNCFHKG_00796 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KKNCFHKG_00797 2.1e-226 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KKNCFHKG_00798 7.3e-133 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KKNCFHKG_00799 7e-60 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KKNCFHKG_00800 4e-75 flgC N Belongs to the flagella basal body rod proteins family
KKNCFHKG_00801 6.4e-40 fliE N Flagellar hook-basal body complex protein FliE
KKNCFHKG_00802 1.3e-242 fliF N The M ring may be actively involved in energy transduction
KKNCFHKG_00803 2e-162 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KKNCFHKG_00804 2.1e-124 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KKNCFHKG_00805 1.2e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KKNCFHKG_00806 3.5e-68 fliJ N Flagellar biosynthesis chaperone
KKNCFHKG_00807 5.4e-38 ylxF S MgtE intracellular N domain
KKNCFHKG_00808 1.3e-293 fliK N Flagellar hook-length control
KKNCFHKG_00809 2.3e-108 flgD N Flagellar basal body rod modification protein
KKNCFHKG_00810 3.2e-72 flg N Putative flagellar
KKNCFHKG_00811 3.1e-115 flgG N Flagellar basal body rod
KKNCFHKG_00812 1.3e-64 fliL N Controls the rotational direction of flagella during chemotaxis
KKNCFHKG_00813 4.9e-182 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KKNCFHKG_00814 1.2e-173 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KKNCFHKG_00815 2.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KKNCFHKG_00816 3.2e-116 fliZ N Flagellar biosynthesis protein, FliO
KKNCFHKG_00817 2.6e-107 fliP N Plays a role in the flagellum-specific transport system
KKNCFHKG_00818 1.5e-37 fliQ N Role in flagellar biosynthesis
KKNCFHKG_00819 8.6e-134 fliR N Flagellar biosynthetic protein FliR
KKNCFHKG_00820 3.5e-186 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKNCFHKG_00821 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKNCFHKG_00822 2.1e-197 flhF N Flagellar biosynthesis regulator FlhF
KKNCFHKG_00823 1.2e-144 flhG D Belongs to the ParA family
KKNCFHKG_00824 1.4e-113 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KKNCFHKG_00825 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KKNCFHKG_00826 8.2e-70 cheW NT COG0835 Chemotaxis signal transduction protein
KKNCFHKG_00827 1.2e-112 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KKNCFHKG_00828 8.9e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KKNCFHKG_00829 1.1e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_00830 1.4e-69 ylxL
KKNCFHKG_00831 1.5e-135 rpsB J Belongs to the universal ribosomal protein uS2 family
KKNCFHKG_00832 1.8e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KKNCFHKG_00833 1.1e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KKNCFHKG_00834 6.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KKNCFHKG_00835 1.1e-147 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKNCFHKG_00836 3.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
KKNCFHKG_00837 1.7e-194 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KKNCFHKG_00838 3.3e-236 rasP M zinc metalloprotease
KKNCFHKG_00839 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KKNCFHKG_00840 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKNCFHKG_00841 7.1e-83 rimP S Required for maturation of 30S ribosomal subunits
KKNCFHKG_00842 8.1e-224 nusA K Participates in both transcription termination and antitermination
KKNCFHKG_00843 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
KKNCFHKG_00844 2.9e-48 ylxQ J ribosomal protein
KKNCFHKG_00845 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKNCFHKG_00846 8.6e-44 ylxP S protein conserved in bacteria
KKNCFHKG_00847 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKNCFHKG_00848 2.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKNCFHKG_00849 3.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KKNCFHKG_00850 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KKNCFHKG_00851 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KKNCFHKG_00852 1.2e-208 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KKNCFHKG_00853 2.4e-231 pepR S Belongs to the peptidase M16 family
KKNCFHKG_00854 1.4e-37 ymxH S YlmC YmxH family
KKNCFHKG_00855 2.5e-186 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KKNCFHKG_00856 2.6e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KKNCFHKG_00857 9.9e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KKNCFHKG_00858 1.1e-228 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KKNCFHKG_00859 3.9e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKNCFHKG_00860 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKNCFHKG_00861 2.2e-131 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KKNCFHKG_00862 4.3e-35 S YlzJ-like protein
KKNCFHKG_00863 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KKNCFHKG_00864 9.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KKNCFHKG_00865 8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KKNCFHKG_00866 5.8e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
KKNCFHKG_00867 1.8e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
KKNCFHKG_00868 2.1e-238 ymfF S Peptidase M16
KKNCFHKG_00869 2e-244 ymfH S zinc protease
KKNCFHKG_00870 5e-128 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KKNCFHKG_00871 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
KKNCFHKG_00872 1e-142 ymfK S Protein of unknown function (DUF3388)
KKNCFHKG_00873 9.9e-137 ymfM S protein conserved in bacteria
KKNCFHKG_00874 1.3e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKNCFHKG_00875 2.4e-223 cinA 3.5.1.42 S Belongs to the CinA family
KKNCFHKG_00876 4.9e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKNCFHKG_00878 2.3e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
KKNCFHKG_00880 7.2e-138 I alpha/beta hydrolase fold
KKNCFHKG_00881 2.6e-95 1.5.1.38 S FMN reductase
KKNCFHKG_00882 2.5e-27 K sequence-specific DNA binding
KKNCFHKG_00883 2.2e-240 yhaO L Calcineurin-like phosphoesterase superfamily domain
KKNCFHKG_00884 0.0 L AAA domain
KKNCFHKG_00885 8.5e-57 mmgB 1.1.1.157 I Dehydrogenase
KKNCFHKG_00886 4.8e-53 mmgB 1.1.1.157 I Dehydrogenase
KKNCFHKG_00887 5.7e-245 yeeO V Mate efflux family protein
KKNCFHKG_00889 5.7e-112 yhbD K Protein of unknown function (DUF4004)
KKNCFHKG_00890 1.4e-225 yhdR 2.6.1.1 E Aminotransferase
KKNCFHKG_00891 1.5e-109 proA_2 H Methyltransferase
KKNCFHKG_00892 0.0 rafA 3.2.1.22 G Alpha-galactosidase
KKNCFHKG_00893 1.1e-50 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKNCFHKG_00894 4.7e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKNCFHKG_00895 1.7e-16 G Peptidase_C39 like family
KKNCFHKG_00896 2.7e-81 thiW S Thiamine-precursor transporter protein (ThiW)
KKNCFHKG_00897 4.1e-26 yjhE S Phage tail protein
KKNCFHKG_00898 1.5e-146 hel M 5'-nucleotidase, lipoprotein e(P4)
KKNCFHKG_00901 1.8e-209 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KKNCFHKG_00902 2.5e-35 K ArsR family transcriptional regulator
KKNCFHKG_00903 2.5e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKNCFHKG_00904 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKNCFHKG_00905 8.3e-279 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KKNCFHKG_00906 4.1e-200 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
KKNCFHKG_00907 1.1e-181 K Transcriptional regulator
KKNCFHKG_00909 1.5e-31 S Cold-inducible protein YdjO
KKNCFHKG_00910 5.7e-14
KKNCFHKG_00912 1.2e-165 cvfB S protein conserved in bacteria
KKNCFHKG_00913 4.4e-70 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKNCFHKG_00914 5.1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KKNCFHKG_00915 6.2e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KKNCFHKG_00916 6.2e-274 yusP P Major facilitator superfamily
KKNCFHKG_00917 1.8e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKNCFHKG_00918 8.3e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KKNCFHKG_00919 2.8e-123 gntR1 K transcriptional
KKNCFHKG_00920 4.1e-170 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KKNCFHKG_00921 5.9e-240 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KKNCFHKG_00922 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KKNCFHKG_00923 3.5e-167 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KKNCFHKG_00924 4e-113 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KKNCFHKG_00925 5.1e-207 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KKNCFHKG_00926 1.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKNCFHKG_00927 6.4e-260 yfnA E amino acid
KKNCFHKG_00928 1.4e-153 degV S protein conserved in bacteria
KKNCFHKG_00929 1.9e-253 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KKNCFHKG_00930 1.5e-132 comFC S Phosphoribosyl transferase domain
KKNCFHKG_00931 4.2e-68 yvyF S flagellar protein
KKNCFHKG_00932 8.8e-38 flgM KNU Negative regulator of flagellin synthesis
KKNCFHKG_00933 6.5e-68 flgN NOU FlgN protein
KKNCFHKG_00934 1.5e-286 flgK N flagellar hook-associated protein
KKNCFHKG_00935 4.3e-153 flgL N Belongs to the bacterial flagellin family
KKNCFHKG_00936 9.5e-77 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KKNCFHKG_00937 1.8e-34 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KKNCFHKG_00938 5e-129 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KKNCFHKG_00939 3.8e-07 fliC N Bacterial flagellin C-terminal helical region
KKNCFHKG_00940 3e-96 K Glycerol-3-phosphate responsive antiterminator
KKNCFHKG_00941 1.5e-113 sapB S MgtC SapB transporter
KKNCFHKG_00942 2.2e-151 araL 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KKNCFHKG_00943 6.3e-145 G myo-inosose-2 dehydratase activity
KKNCFHKG_00944 5.5e-245 EGP Sugar (and other) transporter
KKNCFHKG_00946 3.5e-178 E COG1113 Gamma-aminobutyrate permease and related permeases
KKNCFHKG_00947 0.0 ycbZ 3.4.21.53 O AAA domain
KKNCFHKG_00949 3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KKNCFHKG_00950 7.8e-61 flaG N flagellar protein FlaG
KKNCFHKG_00951 2.3e-234 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KKNCFHKG_00952 1.6e-67 fliS N flagellar protein FliS
KKNCFHKG_00953 5.7e-53 fliT S bacterial-type flagellum organization
KKNCFHKG_00954 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KKNCFHKG_00955 2.6e-306 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KKNCFHKG_00956 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KKNCFHKG_00957 1.8e-168 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKNCFHKG_00958 2.6e-155 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KKNCFHKG_00959 5.5e-50 cccB C COG2010 Cytochrome c, mono- and diheme variants
KKNCFHKG_00960 7.1e-124 ftsE D cell division ATP-binding protein FtsE
KKNCFHKG_00961 4.5e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KKNCFHKG_00962 2.2e-89 D peptidase
KKNCFHKG_00963 6.2e-271 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKNCFHKG_00964 4.3e-247 metY 2.5.1.49 E O-acetylhomoserine
KKNCFHKG_00965 3.3e-183 1.1.1.3 E homoserine dehydrogenase
KKNCFHKG_00966 9.2e-267 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KKNCFHKG_00967 1.8e-199 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKNCFHKG_00968 2.6e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKNCFHKG_00969 7.4e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKNCFHKG_00970 6.2e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KKNCFHKG_00971 5.9e-169 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KKNCFHKG_00972 1.6e-82
KKNCFHKG_00973 3.6e-20
KKNCFHKG_00974 8.4e-32 S Family of unknown function (DUF5316)
KKNCFHKG_00975 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KKNCFHKG_00976 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_00977 4.1e-28 S Family of unknown function (DUF5316)
KKNCFHKG_00978 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KKNCFHKG_00979 4.4e-218 essB S WXG100 protein secretion system (Wss), protein YukC
KKNCFHKG_00980 1.8e-38 yukD S WXG100 protein secretion system (Wss), protein YukD
KKNCFHKG_00981 3.3e-234 esaA S domain protein
KKNCFHKG_00982 2.5e-211 yxjG 2.1.1.14 E Methionine synthase
KKNCFHKG_00983 7e-223 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKNCFHKG_00984 1.4e-148 pocR K Sensory domain found in PocR
KKNCFHKG_00986 1.4e-37 L Belongs to the 'phage' integrase family
KKNCFHKG_00987 3.6e-82 ywrC K Transcriptional regulator
KKNCFHKG_00988 6.3e-100 chrA P COG2059 Chromate transport protein ChrA
KKNCFHKG_00989 1.3e-91 ywrA P COG2059 Chromate transport protein ChrA
KKNCFHKG_00990 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
KKNCFHKG_00991 7e-34 ykuS S Belongs to the UPF0180 family
KKNCFHKG_00992 0.0 pepF2 E COG1164 Oligoendopeptidase F
KKNCFHKG_00993 7.3e-258 pepC 3.4.22.40 E Papain family cysteine protease
KKNCFHKG_00994 1e-213 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KKNCFHKG_00995 3.6e-168 yhaQ S ABC transporter, ATP-binding protein
KKNCFHKG_00996 4.8e-79 IQ Enoyl-(Acyl carrier protein) reductase
KKNCFHKG_00997 1.7e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KKNCFHKG_01003 8.1e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
KKNCFHKG_01004 4.8e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KKNCFHKG_01005 7.9e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKNCFHKG_01007 4.5e-39 spoVIF S Stage VI sporulation protein F
KKNCFHKG_01009 3.3e-56 spoVAE S stage V sporulation protein
KKNCFHKG_01010 1.8e-187 spoVAD I Stage V sporulation protein AD
KKNCFHKG_01011 3.6e-82 spoVAC S stage V sporulation protein AC
KKNCFHKG_01012 3.6e-79 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KKNCFHKG_01014 8.4e-60 S Protein of unknown function (DUF1360)
KKNCFHKG_01015 9.6e-82 cotY S Spore coat protein
KKNCFHKG_01018 7.3e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KKNCFHKG_01019 4.5e-137 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KKNCFHKG_01020 1.5e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKNCFHKG_01021 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKNCFHKG_01022 1.2e-120 yjbM 2.7.6.5 S GTP pyrophosphokinase
KKNCFHKG_01023 4.9e-66 yjbL S Belongs to the UPF0738 family
KKNCFHKG_01024 5.5e-101 yjbK S protein conserved in bacteria
KKNCFHKG_01025 2.6e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KKNCFHKG_01026 1.5e-73 yjbI S COG2346 Truncated hemoglobins
KKNCFHKG_01027 5e-159 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KKNCFHKG_01029 0.0 pepF E oligoendopeptidase F
KKNCFHKG_01030 5.1e-226 yjbF S Competence protein
KKNCFHKG_01031 1.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KKNCFHKG_01032 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KKNCFHKG_01033 1.1e-172 oppF E Belongs to the ABC transporter superfamily
KKNCFHKG_01034 1.1e-195 oppD P Belongs to the ABC transporter superfamily
KKNCFHKG_01035 6.1e-180 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKNCFHKG_01036 6.4e-152 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKNCFHKG_01037 1.3e-299 dppE_1 E ABC transporter substrate-binding protein
KKNCFHKG_01038 3.1e-48 S Domain of unknown function (DUF3899)
KKNCFHKG_01039 1.7e-182 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KKNCFHKG_01040 5e-147 yjbA S Belongs to the UPF0736 family
KKNCFHKG_01041 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
KKNCFHKG_01042 4.5e-134 oppC EP binding-protein-dependent transport systems inner membrane component
KKNCFHKG_01043 1.1e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKNCFHKG_01044 1.3e-176 oppF P Belongs to the ABC transporter superfamily
KKNCFHKG_01045 1.2e-191 oppD P Belongs to the ABC transporter superfamily
KKNCFHKG_01046 2.8e-148 yjaZ O Zn-dependent protease
KKNCFHKG_01047 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KKNCFHKG_01048 3.3e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKNCFHKG_01050 5.1e-147 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KKNCFHKG_01051 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KKNCFHKG_01052 6.2e-27 yjzC S YjzC-like protein
KKNCFHKG_01053 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
KKNCFHKG_01054 2.7e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KKNCFHKG_01055 6.3e-25 S Protein of unknown function (DUF3813)
KKNCFHKG_01056 3.6e-157 yitS S protein conserved in bacteria
KKNCFHKG_01057 1.5e-103 yisN S Protein of unknown function (DUF2777)
KKNCFHKG_01058 3.3e-59 yisL S UPF0344 protein
KKNCFHKG_01059 1.3e-162 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KKNCFHKG_01060 1.9e-222 P Protein of unknown function (DUF418)
KKNCFHKG_01061 1.6e-32 gerPA S Spore germination protein
KKNCFHKG_01062 1.4e-97 gerPC S Spore germination protein
KKNCFHKG_01063 2e-25 gerPD S Spore germination protein
KKNCFHKG_01064 2.9e-70 gerPE S Spore germination protein GerPE
KKNCFHKG_01065 4.7e-29 gerPF S Spore germination protein gerPA/gerPF
KKNCFHKG_01066 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KKNCFHKG_01067 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KKNCFHKG_01069 1.8e-142 S Mitochondrial biogenesis AIM24
KKNCFHKG_01070 8.2e-96 comK K Competence transcription factor
KKNCFHKG_01071 3.7e-08 S IDEAL
KKNCFHKG_01072 8.4e-208 yhfN 3.4.24.84 O Peptidase M48
KKNCFHKG_01073 5.7e-41 azlD S branched-chain amino acid
KKNCFHKG_01074 7.9e-118 azlC E AzlC protein
KKNCFHKG_01075 1.1e-294 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
KKNCFHKG_01076 8.5e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
KKNCFHKG_01077 3.1e-64 ytkA S YtkA-like
KKNCFHKG_01078 9.7e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KKNCFHKG_01079 1.5e-17 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKNCFHKG_01080 4.1e-162 EG EamA-like transporter family
KKNCFHKG_01081 2.9e-58 EGP Major facilitator Superfamily
KKNCFHKG_01082 2.3e-146 yhgE S YhgE Pip N-terminal domain protein
KKNCFHKG_01083 2.4e-101 yhgD K Transcriptional regulator
KKNCFHKG_01084 6.8e-104 2.7.1.202 K transcriptional regulator, MtlR
KKNCFHKG_01085 1.7e-35 2.7.1.202 K transcriptional regulator, MtlR
KKNCFHKG_01086 1.5e-31 2.7.1.196, 2.7.1.205 G phosphotransferase system
KKNCFHKG_01087 3.5e-161 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKNCFHKG_01088 1.2e-64 S Protein of unknown function (DUF2512)
KKNCFHKG_01089 2.5e-18 L PFAM Transposase, IS116 IS110 IS902
KKNCFHKG_01090 2.5e-155 kdsA 2.5.1.55 M Belongs to the KdsA family
KKNCFHKG_01091 1.1e-175 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
KKNCFHKG_01092 2.9e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKNCFHKG_01093 3.9e-215 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKNCFHKG_01094 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
KKNCFHKG_01095 3.2e-147 G Binding-protein-dependent transport system inner membrane component
KKNCFHKG_01096 2e-217 sugA G Binding-protein-dependent transport system inner membrane component
KKNCFHKG_01097 1.7e-224 G Bacterial extracellular solute-binding protein
KKNCFHKG_01098 9.4e-130 K helix_turn_helix, arabinose operon control protein
KKNCFHKG_01099 1.6e-137 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KKNCFHKG_01100 1.5e-52 S Iron-sulphur cluster biosynthesis
KKNCFHKG_01101 1.1e-175 yhfP 1.1.1.1 C Quinone oxidoreductase
KKNCFHKG_01102 1.3e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KKNCFHKG_01103 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KKNCFHKG_01104 1.9e-72 3.4.21.121 O Belongs to the peptidase S8 family
KKNCFHKG_01105 2e-83
KKNCFHKG_01106 6e-146 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KKNCFHKG_01107 9.5e-29 IQ Short-chain dehydrogenase reductase sdr
KKNCFHKG_01108 2.3e-28 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KKNCFHKG_01109 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KKNCFHKG_01110 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKNCFHKG_01111 6.6e-157 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KKNCFHKG_01112 1.2e-123 yhcW 5.4.2.6 S hydrolase
KKNCFHKG_01113 2.5e-164 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KKNCFHKG_01114 1.3e-125 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KKNCFHKG_01115 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KKNCFHKG_01116 6.3e-260 G Major facilitator Superfamily
KKNCFHKG_01117 3.2e-186 malR K Transcriptional regulator
KKNCFHKG_01118 9.7e-21 T PhoQ Sensor
KKNCFHKG_01119 2.2e-19
KKNCFHKG_01120 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KKNCFHKG_01122 9.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KKNCFHKG_01123 9.1e-74 yabE S 3D domain
KKNCFHKG_01124 2e-32 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
KKNCFHKG_01125 0.0 pip S YhgE Pip N-terminal domain protein
KKNCFHKG_01126 2.9e-48 yqgV S Thiamine-binding protein
KKNCFHKG_01127 4.2e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
KKNCFHKG_01128 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KKNCFHKG_01129 0.0 levR K PTS system fructose IIA component
KKNCFHKG_01130 4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
KKNCFHKG_01131 1.6e-177 manL 2.7.1.191 G PTS system mannose fructose sorbose family
KKNCFHKG_01132 1.2e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KKNCFHKG_01133 9e-167 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KKNCFHKG_01135 1.6e-64 manO S Domain of unknown function (DUF956)
KKNCFHKG_01136 5.6e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KKNCFHKG_01137 6.9e-278 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KKNCFHKG_01138 1.9e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KKNCFHKG_01139 2.7e-85 S Heat induced stress protein YflT
KKNCFHKG_01140 1.5e-253 nylA 3.5.1.4 J Belongs to the amidase family
KKNCFHKG_01141 1.4e-50 M1-594 S Thiamine-binding protein
KKNCFHKG_01142 8.4e-137 ssuC_1 P binding-protein-dependent transport systems inner membrane component
KKNCFHKG_01143 2.9e-182 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KKNCFHKG_01144 6.3e-134 P ABC transporter, ATP-binding protein
KKNCFHKG_01145 3.1e-159 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KKNCFHKG_01146 5.2e-190 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KKNCFHKG_01147 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
KKNCFHKG_01148 1.6e-148 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KKNCFHKG_01149 8.6e-16 S Protein of unknown function (DUF4064)
KKNCFHKG_01150 5e-284 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KKNCFHKG_01151 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KKNCFHKG_01152 9.6e-48 yhdT S Sodium pantothenate symporter
KKNCFHKG_01153 8.8e-233 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKNCFHKG_01156 4.5e-169 corA P Mg2 transporter protein CorA family protein
KKNCFHKG_01157 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KKNCFHKG_01158 8.5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KKNCFHKG_01159 3.2e-76
KKNCFHKG_01160 3.6e-76 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KKNCFHKG_01161 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KKNCFHKG_01162 7.9e-100 bioY S Biotin biosynthesis protein
KKNCFHKG_01163 1.7e-187 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKNCFHKG_01164 8.5e-148 aacC 2.3.1.81 V aminoglycoside
KKNCFHKG_01165 8.1e-217 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKNCFHKG_01166 2.8e-70 yxiE T Belongs to the universal stress protein A family
KKNCFHKG_01167 2.4e-27
KKNCFHKG_01168 1.1e-73
KKNCFHKG_01169 6.3e-226 yfkA S YfkB-like domain
KKNCFHKG_01170 6.2e-68 gutA G MFS/sugar transport protein
KKNCFHKG_01171 8.8e-136 IQ Short-chain dehydrogenase reductase sdr
KKNCFHKG_01172 2.3e-72 cymR K Transcriptional regulator
KKNCFHKG_01173 2.6e-208 iscS 2.8.1.7 E Cysteine desulfurase
KKNCFHKG_01174 9.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KKNCFHKG_01175 1.3e-125 S COG0457 FOG TPR repeat
KKNCFHKG_01176 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KKNCFHKG_01177 2.8e-73 yndM S Protein of unknown function (DUF2512)
KKNCFHKG_01178 4e-29 yrzR
KKNCFHKG_01180 4.2e-171 yrrI S AI-2E family transporter
KKNCFHKG_01181 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KKNCFHKG_01182 1.1e-43 yrzL S Belongs to the UPF0297 family
KKNCFHKG_01183 6.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KKNCFHKG_01184 1.5e-41 yrzB S Belongs to the UPF0473 family
KKNCFHKG_01185 8e-202 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKNCFHKG_01186 3.7e-114 yrrM 2.1.1.104 S O-methyltransferase
KKNCFHKG_01187 1.7e-111 udk 2.7.1.48 F Cytidine monophosphokinase
KKNCFHKG_01188 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KKNCFHKG_01189 7.9e-58 yrrS S Protein of unknown function (DUF1510)
KKNCFHKG_01190 6.4e-28 yrzA S Protein of unknown function (DUF2536)
KKNCFHKG_01191 4.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KKNCFHKG_01192 2.9e-10 S YrhC-like protein
KKNCFHKG_01194 3.8e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KKNCFHKG_01195 6.2e-293 ahpF O Alkyl hydroperoxide reductase
KKNCFHKG_01196 1.8e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_01197 6.7e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKNCFHKG_01198 7.2e-15 sda S Sporulation inhibitor A
KKNCFHKG_01199 1.7e-149 czcD P COG1230 Co Zn Cd efflux system component
KKNCFHKG_01200 9.1e-119 S VIT family
KKNCFHKG_01201 3.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKNCFHKG_01202 1.2e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKNCFHKG_01203 6.5e-78 lemA S LemA family
KKNCFHKG_01204 1.3e-116 S TPM domain
KKNCFHKG_01205 1.2e-98 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KKNCFHKG_01206 2.7e-22 S Short C-terminal domain
KKNCFHKG_01207 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
KKNCFHKG_01208 5.1e-225 mco 1.16.3.3 Q multicopper oxidases
KKNCFHKG_01209 1.6e-205 ysfB KT regulator
KKNCFHKG_01210 7.7e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
KKNCFHKG_01211 8.1e-257 glcF C Glycolate oxidase
KKNCFHKG_01212 3.8e-93 yqeG S hydrolase of the HAD superfamily
KKNCFHKG_01213 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KKNCFHKG_01214 8.1e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKNCFHKG_01215 2.4e-44 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KKNCFHKG_01216 5e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKNCFHKG_01217 3.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KKNCFHKG_01218 1.4e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KKNCFHKG_01219 2.5e-146 cmoA S Methyltransferase domain
KKNCFHKG_01220 1.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKNCFHKG_01221 8.8e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KKNCFHKG_01222 2.1e-111 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
KKNCFHKG_01223 0.0 comEC S Competence protein ComEC
KKNCFHKG_01225 1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
KKNCFHKG_01226 3.7e-33 rpsT J Binds directly to 16S ribosomal RNA
KKNCFHKG_01227 4.7e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KKNCFHKG_01228 3.8e-221 spoIIP M stage II sporulation protein P
KKNCFHKG_01229 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KKNCFHKG_01230 9.7e-219 hemN H Involved in the biosynthesis of porphyrin-containing compound
KKNCFHKG_01231 6.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KKNCFHKG_01232 2.1e-88 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKNCFHKG_01233 1.4e-307 dnaK O Heat shock 70 kDa protein
KKNCFHKG_01234 4.2e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KKNCFHKG_01235 1.5e-172 prmA J Methylates ribosomal protein L11
KKNCFHKG_01236 7.8e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KKNCFHKG_01237 4.2e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KKNCFHKG_01238 1.6e-155 yqeW P COG1283 Na phosphate symporter
KKNCFHKG_01239 2.6e-48 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KKNCFHKG_01240 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KKNCFHKG_01241 6.6e-70 yqeY S Yqey-like protein
KKNCFHKG_01242 3.2e-46 yqfC S sporulation protein YqfC
KKNCFHKG_01243 1.2e-224 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KKNCFHKG_01244 6.1e-174 phoH T Phosphate starvation-inducible protein PhoH
KKNCFHKG_01245 5.4e-55 yqfF S membrane-associated HD superfamily hydrolase
KKNCFHKG_01246 2.9e-162 yqfF S membrane-associated HD superfamily hydrolase
KKNCFHKG_01247 4.2e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKNCFHKG_01248 7.9e-67 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KKNCFHKG_01249 5.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKNCFHKG_01250 3e-08 S YqzL-like protein
KKNCFHKG_01251 1.6e-145 recO L Involved in DNA repair and RecF pathway recombination
KKNCFHKG_01252 2.2e-111 ccpN K CBS domain
KKNCFHKG_01253 5.5e-144 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KKNCFHKG_01254 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KKNCFHKG_01255 2.8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KKNCFHKG_01256 5.8e-89
KKNCFHKG_01257 1.5e-64 cccA C Cytochrome C oxidase, cbb3-type, subunit III
KKNCFHKG_01258 6.6e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
KKNCFHKG_01259 8.4e-207 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KKNCFHKG_01260 9.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KKNCFHKG_01261 2.2e-63 erpA S Belongs to the HesB IscA family
KKNCFHKG_01262 1.1e-59 yuzD S protein conserved in bacteria
KKNCFHKG_01263 8.6e-37 nifU O COG0694 Thioredoxin-like proteins and domains
KKNCFHKG_01264 3.1e-200 yutH S Spore coat protein
KKNCFHKG_01265 1.1e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KKNCFHKG_01266 7.4e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KKNCFHKG_01267 4.3e-74 yutE S Protein of unknown function DUF86
KKNCFHKG_01268 2.6e-48 yutD S protein conserved in bacteria
KKNCFHKG_01269 1e-173 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KKNCFHKG_01270 6.7e-200 lytH M Peptidase, M23
KKNCFHKG_01271 1e-125 yunB S Sporulation protein YunB (Spo_YunB)
KKNCFHKG_01272 5.3e-47 yunC S Domain of unknown function (DUF1805)
KKNCFHKG_01273 3.4e-277 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KKNCFHKG_01274 2.2e-273 sufB O FeS cluster assembly
KKNCFHKG_01275 1.4e-75 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KKNCFHKG_01276 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KKNCFHKG_01277 2.3e-240 sufD O assembly protein SufD
KKNCFHKG_01278 1.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KKNCFHKG_01280 1.5e-49 traF CO Thioredoxin
KKNCFHKG_01281 5.1e-63 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KKNCFHKG_01282 3.1e-62 arsC 1.20.4.1 P Belongs to the ArsC family
KKNCFHKG_01283 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KKNCFHKG_01284 1.5e-214 fadA 2.3.1.16 I Belongs to the thiolase family
KKNCFHKG_01285 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KKNCFHKG_01286 2.6e-14 S YuzL-like protein
KKNCFHKG_01287 2.4e-40
KKNCFHKG_01288 7.1e-56 yusN M Coat F domain
KKNCFHKG_01289 1.3e-213 rodA D Belongs to the SEDS family
KKNCFHKG_01290 5.7e-70 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKNCFHKG_01291 4.3e-280 cls2 I PLD-like domain
KKNCFHKG_01293 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKNCFHKG_01294 5.6e-189 M1-600 T Putative diguanylate phosphodiesterase
KKNCFHKG_01295 1.1e-297 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KKNCFHKG_01296 3.5e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KKNCFHKG_01297 2.9e-139 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
KKNCFHKG_01298 4.5e-241 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
KKNCFHKG_01299 1.7e-122
KKNCFHKG_01300 3.4e-83 S Putative zinc-finger
KKNCFHKG_01301 3.7e-88 K Belongs to the sigma-70 factor family. ECF subfamily
KKNCFHKG_01302 6.9e-220 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KKNCFHKG_01303 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
KKNCFHKG_01304 2.7e-235 NU cell adhesion
KKNCFHKG_01306 3.3e-21 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KKNCFHKG_01307 1.9e-75 K helix_turn_helix isocitrate lyase regulation
KKNCFHKG_01308 1.7e-19 L Winged helix-turn helix
KKNCFHKG_01309 2.9e-36 uraH 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KKNCFHKG_01310 2.1e-210 P Monooxygenase
KKNCFHKG_01311 2.2e-42 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
KKNCFHKG_01312 3e-155 pbuX F Permease family
KKNCFHKG_01313 6e-166 pucR QT COG2508 Regulator of polyketide synthase expression
KKNCFHKG_01314 1e-144 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KKNCFHKG_01315 7.7e-201 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KKNCFHKG_01316 5.2e-182 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KKNCFHKG_01317 2.9e-19 G M42 glutamyl aminopeptidase
KKNCFHKG_01318 1.6e-280 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KKNCFHKG_01320 2.8e-18
KKNCFHKG_01321 5.7e-10 S transposase or invertase
KKNCFHKG_01322 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KKNCFHKG_01323 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KKNCFHKG_01324 3.4e-143 est 3.1.1.1 S Carboxylesterase
KKNCFHKG_01325 2.5e-28 secG U Preprotein translocase subunit SecG
KKNCFHKG_01326 1.3e-240 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKNCFHKG_01328 2.3e-300 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KKNCFHKG_01329 2.5e-122 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KKNCFHKG_01330 2.9e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KKNCFHKG_01331 7.6e-183 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KKNCFHKG_01332 1.4e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KKNCFHKG_01333 2.3e-39 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KKNCFHKG_01334 1.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KKNCFHKG_01336 1.3e-07 S Heavy-metal-associated domain
KKNCFHKG_01337 1.7e-82 S Protein of unknown function (DUF1641)
KKNCFHKG_01339 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KKNCFHKG_01340 1.7e-31
KKNCFHKG_01341 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KKNCFHKG_01342 2.5e-123 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KKNCFHKG_01343 3.8e-119 acuB S Acetoin utilization protein AcuB
KKNCFHKG_01344 1.6e-232 acuC BQ histone deacetylase
KKNCFHKG_01345 2.2e-182 ccpA K catabolite control protein A
KKNCFHKG_01346 1.4e-190 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KKNCFHKG_01347 1.7e-34 XK27_07760 S COG4980 Gas vesicle protein
KKNCFHKG_01348 2.5e-44 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KKNCFHKG_01349 2.2e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KKNCFHKG_01350 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KKNCFHKG_01351 1.2e-66 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KKNCFHKG_01352 1.1e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKNCFHKG_01353 4.8e-148 ytpQ S Belongs to the UPF0354 family
KKNCFHKG_01354 1.9e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKNCFHKG_01355 8.8e-196 rsbU 3.1.3.3 T response regulator
KKNCFHKG_01356 8.9e-153 cheR 2.1.1.80 NT chemotaxis
KKNCFHKG_01357 0.0 T PhoQ Sensor
KKNCFHKG_01358 6.6e-53 ytzB S small secreted protein
KKNCFHKG_01359 1.5e-171 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KKNCFHKG_01361 5.1e-130 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KKNCFHKG_01362 2.7e-55 ytzH S YtzH-like protein
KKNCFHKG_01363 4.8e-156 ytmP 2.7.1.89 M Phosphotransferase
KKNCFHKG_01365 5.4e-146 ytlQ
KKNCFHKG_01366 7.7e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KKNCFHKG_01368 1.2e-160 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KKNCFHKG_01369 1e-273 pepV 3.5.1.18 E Dipeptidase
KKNCFHKG_01370 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KKNCFHKG_01371 2.6e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKNCFHKG_01372 6.4e-27 yteV S Sporulation protein Cse60
KKNCFHKG_01374 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKNCFHKG_01375 1.6e-187 yttB EGP Major facilitator Superfamily
KKNCFHKG_01376 9.4e-43 ytzC S Protein of unknown function (DUF2524)
KKNCFHKG_01377 8.3e-102 ytqB J Putative rRNA methylase
KKNCFHKG_01378 1.7e-207 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KKNCFHKG_01379 1.7e-153 ytpA 3.1.1.5 I Alpha beta hydrolase
KKNCFHKG_01380 5.6e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KKNCFHKG_01381 0.0 asnB 6.3.5.4 E Asparagine synthase
KKNCFHKG_01382 9.3e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KKNCFHKG_01383 1.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KKNCFHKG_01384 2.8e-55 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
KKNCFHKG_01385 1.9e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KKNCFHKG_01386 1.9e-100 ywqN S NAD(P)H-dependent
KKNCFHKG_01387 3.1e-56 gntK 2.7.1.12, 2.7.1.17 G FGGY family of carbohydrate kinases, N-terminal domain
KKNCFHKG_01388 1.9e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KKNCFHKG_01389 3e-139 ytlC P ABC transporter
KKNCFHKG_01390 1.6e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KKNCFHKG_01391 9.8e-85 ytkD 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KKNCFHKG_01392 7.4e-39
KKNCFHKG_01393 2.8e-76 dps P Belongs to the Dps family
KKNCFHKG_01394 6.4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KKNCFHKG_01396 1.2e-158 adcA P Belongs to the bacterial solute-binding protein 9 family
KKNCFHKG_01397 7.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KKNCFHKG_01398 4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KKNCFHKG_01399 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KKNCFHKG_01400 1.5e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KKNCFHKG_01401 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KKNCFHKG_01402 3.9e-251 menF 5.4.4.2 HQ Isochorismate synthase
KKNCFHKG_01403 9.4e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KKNCFHKG_01413 3e-09
KKNCFHKG_01419 5.1e-08
KKNCFHKG_01420 1.6e-08
KKNCFHKG_01424 1.6e-42
KKNCFHKG_01427 4.3e-42 S COG NOG14552 non supervised orthologous group
KKNCFHKG_01428 0.0 cydD V ATP-binding protein
KKNCFHKG_01429 0.0 cydD V ATP-binding
KKNCFHKG_01430 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KKNCFHKG_01431 4.3e-261 cydA 1.10.3.14 C oxidase, subunit
KKNCFHKG_01432 2.6e-30
KKNCFHKG_01433 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
KKNCFHKG_01434 4.9e-76
KKNCFHKG_01435 1.2e-58 yrkC G Cupin domain
KKNCFHKG_01436 1.3e-173 K Transcriptional regulator
KKNCFHKG_01437 1.4e-211 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
KKNCFHKG_01438 1.6e-101 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KKNCFHKG_01439 1.4e-61 gerD S Spore gernimation protein
KKNCFHKG_01440 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KKNCFHKG_01441 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKNCFHKG_01442 2.8e-81 ybaK S Protein of unknown function (DUF2521)
KKNCFHKG_01443 1.1e-273 lysP E amino acid
KKNCFHKG_01444 2.8e-111 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KKNCFHKG_01445 3.7e-226 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KKNCFHKG_01447 6.7e-10 S Protein conserved in bacteria
KKNCFHKG_01448 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KKNCFHKG_01449 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KKNCFHKG_01450 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KKNCFHKG_01451 4.6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKNCFHKG_01452 2.2e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKNCFHKG_01453 2.4e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKNCFHKG_01454 5.8e-65 rplQ J Ribosomal protein L17
KKNCFHKG_01455 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKNCFHKG_01456 2e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KKNCFHKG_01457 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KKNCFHKG_01458 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KKNCFHKG_01459 9.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KKNCFHKG_01460 6.9e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KKNCFHKG_01461 4.5e-71 rplO J binds to the 23S rRNA
KKNCFHKG_01462 4.1e-23 rpmD J Ribosomal protein L30
KKNCFHKG_01463 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KKNCFHKG_01464 8.8e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KKNCFHKG_01465 1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KKNCFHKG_01466 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KKNCFHKG_01467 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKNCFHKG_01468 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KKNCFHKG_01469 9.6e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KKNCFHKG_01470 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KKNCFHKG_01471 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KKNCFHKG_01472 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KKNCFHKG_01473 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KKNCFHKG_01474 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KKNCFHKG_01475 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KKNCFHKG_01476 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KKNCFHKG_01477 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KKNCFHKG_01478 6.3e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KKNCFHKG_01479 1.1e-107 rplD J Forms part of the polypeptide exit tunnel
KKNCFHKG_01480 2.6e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KKNCFHKG_01481 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KKNCFHKG_01482 1.4e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKNCFHKG_01483 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KKNCFHKG_01484 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KKNCFHKG_01485 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KKNCFHKG_01486 1.3e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
KKNCFHKG_01487 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKNCFHKG_01488 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKNCFHKG_01489 2.5e-112 rsmC 2.1.1.172 J Methyltransferase
KKNCFHKG_01490 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KKNCFHKG_01491 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KKNCFHKG_01492 1e-08 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KKNCFHKG_01493 4.3e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KKNCFHKG_01494 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KKNCFHKG_01495 9.2e-95 nusG K Participates in transcription elongation, termination and antitermination
KKNCFHKG_01496 8.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KKNCFHKG_01497 7.2e-110 sigH K Belongs to the sigma-70 factor family
KKNCFHKG_01498 9.6e-89 yacP S RNA-binding protein containing a PIN domain
KKNCFHKG_01499 1.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKNCFHKG_01500 3e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KKNCFHKG_01501 2.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKNCFHKG_01502 1.4e-113 cysE 2.3.1.30 E Serine acetyltransferase
KKNCFHKG_01503 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKNCFHKG_01504 2.1e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KKNCFHKG_01505 7.5e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KKNCFHKG_01506 6.9e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KKNCFHKG_01507 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KKNCFHKG_01508 0.0 clpC O Belongs to the ClpA ClpB family
KKNCFHKG_01509 2.8e-191 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KKNCFHKG_01510 8.2e-99 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KKNCFHKG_01511 5.4e-75 ctsR K Belongs to the CtsR family
KKNCFHKG_01512 1.9e-90 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KKNCFHKG_01513 2.3e-38 gcvR T Belongs to the UPF0237 family
KKNCFHKG_01514 1.4e-248 XK27_08635 S UPF0210 protein
KKNCFHKG_01517 2.4e-36 ptxS K transcriptional
KKNCFHKG_01518 2.9e-91 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
KKNCFHKG_01519 4e-84 cotF M Spore coat protein
KKNCFHKG_01520 1.1e-175 iolS C Aldo keto reductase
KKNCFHKG_01521 1.2e-97 ydjA C Nitroreductase family
KKNCFHKG_01522 2.6e-250 E COG1113 Gamma-aminobutyrate permease and related permeases
KKNCFHKG_01523 2.4e-273 dtpT E amino acid peptide transporter
KKNCFHKG_01524 1e-276 lysP E amino acid
KKNCFHKG_01526 4.3e-98 puuR K Cupin domain
KKNCFHKG_01527 2.3e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KKNCFHKG_01528 9e-139 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
KKNCFHKG_01529 5.4e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
KKNCFHKG_01530 9.8e-205 potD E COG0687 Spermidine putrescine-binding periplasmic protein
KKNCFHKG_01531 1.4e-248 H HemY protein
KKNCFHKG_01532 3.7e-252 E amino acid
KKNCFHKG_01533 2.7e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KKNCFHKG_01534 2.5e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KKNCFHKG_01535 5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KKNCFHKG_01536 6.9e-251 E Amino acid permease
KKNCFHKG_01537 3.9e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KKNCFHKG_01538 1.2e-233 amt P Ammonium transporter
KKNCFHKG_01539 1.1e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_01540 4.9e-79 citH C Citrate transporter
KKNCFHKG_01541 4.2e-181 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKNCFHKG_01542 0.0 helD 3.6.4.12 L DNA helicase
KKNCFHKG_01546 5.5e-128 L Archaeal putative transposase ISC1217
KKNCFHKG_01547 2.2e-19
KKNCFHKG_01550 2.5e-98 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KKNCFHKG_01551 3.6e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KKNCFHKG_01552 1.1e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KKNCFHKG_01553 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KKNCFHKG_01554 8.3e-211 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKNCFHKG_01555 2.5e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_01556 1.6e-120 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KKNCFHKG_01557 5.2e-122 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
KKNCFHKG_01558 4e-90 S Belongs to the UPF0312 family
KKNCFHKG_01559 2.2e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KKNCFHKG_01561 2.5e-189 T HD domain
KKNCFHKG_01562 2.3e-278 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KKNCFHKG_01563 0.0 ydaO E amino acid
KKNCFHKG_01564 1.4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KKNCFHKG_01565 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KKNCFHKG_01566 1.1e-173 ydbI S AI-2E family transporter
KKNCFHKG_01567 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKNCFHKG_01568 4.7e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
KKNCFHKG_01569 6.1e-109 gluC P ABC transporter
KKNCFHKG_01570 2.1e-115 glnP P ABC transporter
KKNCFHKG_01571 1.3e-218 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KKNCFHKG_01572 5.2e-165 EGP MFS_1 like family
KKNCFHKG_01573 3.8e-55 ywrC K Transcriptional regulator
KKNCFHKG_01574 8.4e-230 S PFAM Uncharacterised protein family UPF0236
KKNCFHKG_01575 3.4e-13 S PFAM Uncharacterised protein family UPF0236
KKNCFHKG_01577 2.7e-253 ybhI P Sodium:sulfate symporter transmembrane region
KKNCFHKG_01578 2e-89 endA 3.1.21.1 L Endonuclease I
KKNCFHKG_01579 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
KKNCFHKG_01581 4e-129
KKNCFHKG_01582 9.2e-127 yhcG V ABC transporter, ATP-binding protein
KKNCFHKG_01583 1.6e-58 yhcF K Transcriptional regulator
KKNCFHKG_01584 4.3e-95 padR K transcriptional
KKNCFHKG_01585 5.6e-94 padC Q Phenolic acid decarboxylase
KKNCFHKG_01586 6.9e-113 ywnB S NAD(P)H-binding
KKNCFHKG_01587 4.4e-86 folT 2.7.13.3 T ECF transporter, substrate-specific component
KKNCFHKG_01588 1.5e-35 yeeD O Belongs to the sulfur carrier protein TusA family
KKNCFHKG_01589 9.4e-192 yeeE S Sulphur transport
KKNCFHKG_01590 1.8e-220 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KKNCFHKG_01591 2.5e-169 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKNCFHKG_01592 1.3e-94 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KKNCFHKG_01593 8.3e-42 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KKNCFHKG_01594 1.7e-61 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KKNCFHKG_01595 5.6e-274 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KKNCFHKG_01596 9.1e-55 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KKNCFHKG_01598 2.5e-155 E Amino acid permease
KKNCFHKG_01600 1.3e-279 tynA 1.4.3.21 Q amine oxidase
KKNCFHKG_01601 4.6e-40 K helix_turn_helix, arabinose operon control protein
KKNCFHKG_01602 2.8e-152 yeaN P COG2807 Cyanate permease
KKNCFHKG_01603 5.8e-187 ubiB S ABC1 family
KKNCFHKG_01604 1.9e-62 ubiB S ABC1 family
KKNCFHKG_01605 4e-15 S ATP synthase, subunit b
KKNCFHKG_01606 1.1e-16 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KKNCFHKG_01607 5.8e-280 scrA 2.7.1.211, 5.3.1.1 G pts system
KKNCFHKG_01608 4.8e-202 scrB 3.2.1.26 GH32 G invertase
KKNCFHKG_01609 1.4e-136 scrR K helix_turn _helix lactose operon repressor
KKNCFHKG_01610 3.1e-93
KKNCFHKG_01612 1.4e-27 K Helix-turn-helix domain
KKNCFHKG_01613 6.1e-31
KKNCFHKG_01614 2.7e-31 S Domain of unknown function (DUF4177)
KKNCFHKG_01615 1.2e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KKNCFHKG_01616 5.2e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KKNCFHKG_01617 9.4e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KKNCFHKG_01618 2.4e-106 pncA Q COG1335 Amidases related to nicotinamidase
KKNCFHKG_01619 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KKNCFHKG_01620 0.0 ykoS
KKNCFHKG_01621 1.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKNCFHKG_01622 4.1e-68 yngA S GtrA-like protein
KKNCFHKG_01623 3.2e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KKNCFHKG_01624 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KKNCFHKG_01625 1.9e-122 ydiL S CAAX protease self-immunity
KKNCFHKG_01626 4.7e-28 S Domain of unknown function (DUF4305)
KKNCFHKG_01627 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKNCFHKG_01628 7.8e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KKNCFHKG_01629 1.1e-09 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KKNCFHKG_01630 0.0 ydiF S ABC transporter
KKNCFHKG_01631 2.3e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KKNCFHKG_01632 2.2e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KKNCFHKG_01633 1.4e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KKNCFHKG_01634 5.3e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KKNCFHKG_01636 1.1e-64 argO S Lysine exporter protein LysE YggA
KKNCFHKG_01637 1.3e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKNCFHKG_01638 6.2e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KKNCFHKG_01639 9.9e-83 S AAA domain
KKNCFHKG_01640 2.1e-85 S Bacterial PH domain
KKNCFHKG_01641 1.4e-273 ydbT S Bacterial PH domain
KKNCFHKG_01642 8.6e-76 yqgC S protein conserved in bacteria
KKNCFHKG_01643 9.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKNCFHKG_01644 4.2e-43
KKNCFHKG_01645 1.6e-69 yoaS S Protein of unknown function (DUF2975)
KKNCFHKG_01646 5.1e-28 yozG K Transcriptional regulator
KKNCFHKG_01647 1.6e-13 yoaT S Protein of unknown function (DUF817)
KKNCFHKG_01648 3e-260 S Protein of unknown function (DUF2397)
KKNCFHKG_01650 8.9e-228 S Protein of unknown function (DUF2398)
KKNCFHKG_01651 0.0 D Putative exonuclease SbcCD, C subunit
KKNCFHKG_01652 5.1e-248 S Protein of unknown function N-terminus (DUF3323)
KKNCFHKG_01653 2.7e-55 yhgE S YhgE Pip N-terminal domain protein
KKNCFHKG_01654 3.1e-20 yhgD K Transcriptional regulator
KKNCFHKG_01655 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KKNCFHKG_01656 7.2e-194 ansA 3.5.1.1 EJ L-asparaginase
KKNCFHKG_01657 2.2e-307 ypdA 2.7.13.3 T Signal transduction histidine kinase
KKNCFHKG_01658 2.1e-137 ypdB KT LytTr DNA-binding domain
KKNCFHKG_01659 5.8e-92 yhjX P Major facilitator superfamily
KKNCFHKG_01660 1.6e-115 yhjX P Major facilitator superfamily
KKNCFHKG_01661 1.7e-215 yxjG 2.1.1.14 E Methionine synthase
KKNCFHKG_01662 2.6e-104 yetJ S Belongs to the BI1 family
KKNCFHKG_01663 1.1e-38 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KKNCFHKG_01664 1e-245
KKNCFHKG_01665 3.8e-151 T STAS domain
KKNCFHKG_01666 3.5e-244 braB E Component of the transport system for branched-chain amino acids
KKNCFHKG_01667 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KKNCFHKG_01668 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KKNCFHKG_01669 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
KKNCFHKG_01670 1.8e-195 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KKNCFHKG_01671 5.8e-283 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KKNCFHKG_01672 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KKNCFHKG_01673 2.6e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKNCFHKG_01674 7.8e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKNCFHKG_01675 7.4e-189 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KKNCFHKG_01676 3.3e-219 2.6.1.9 S HAD-hyrolase-like
KKNCFHKG_01677 1.5e-178 S Phosphotransferase system, EIIC
KKNCFHKG_01678 1.7e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKNCFHKG_01679 1.5e-219 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KKNCFHKG_01680 4.3e-183 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKNCFHKG_01681 3e-239 mcpA NT chemotaxis protein
KKNCFHKG_01684 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KKNCFHKG_01685 1.3e-48 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
KKNCFHKG_01686 1.3e-41
KKNCFHKG_01688 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKNCFHKG_01689 5.6e-88 fld C Flavodoxin
KKNCFHKG_01690 2.2e-193 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKNCFHKG_01691 3.6e-103 plsY 2.3.1.15 I Belongs to the PlsY family
KKNCFHKG_01692 3.3e-208 crtQ M Glycosyl transferase family 21
KKNCFHKG_01693 7.6e-23 S transposase or invertase
KKNCFHKG_01694 1e-92 Q Thioesterase superfamily
KKNCFHKG_01695 2.2e-48 sugE P Multidrug resistance protein
KKNCFHKG_01696 4.9e-49 ykkC P Multidrug resistance protein
KKNCFHKG_01697 1e-134 yfcA S membrane transporter protein
KKNCFHKG_01698 9.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKNCFHKG_01699 2.4e-179 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKNCFHKG_01700 1.6e-169 fhuD P Periplasmic binding protein
KKNCFHKG_01701 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
KKNCFHKG_01702 7.2e-197 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KKNCFHKG_01703 7e-93
KKNCFHKG_01704 1.2e-97
KKNCFHKG_01705 3.2e-127 yeeN K transcriptional regulatory protein
KKNCFHKG_01706 1.5e-186 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
KKNCFHKG_01707 5.4e-251 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKNCFHKG_01708 8.4e-100 glnH ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KKNCFHKG_01709 9.9e-83 yecS_2 E COG0765 ABC-type amino acid transport system, permease component
KKNCFHKG_01710 9.5e-111 artM_2 3.6.3.21 E ABC transporter
KKNCFHKG_01711 4.7e-239 yobO M Pectate lyase superfamily protein
KKNCFHKG_01712 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KKNCFHKG_01713 3.7e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KKNCFHKG_01714 6.3e-126 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KKNCFHKG_01715 3.8e-100 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KKNCFHKG_01716 5.4e-95 ywhH S Aminoacyl-tRNA editing domain
KKNCFHKG_01717 1.1e-203 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KKNCFHKG_01718 3.7e-309 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKNCFHKG_01719 8.7e-182 2.7.7.65 T Diguanylate cyclase, GGDEF domain
KKNCFHKG_01721 7.8e-166 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KKNCFHKG_01722 6.6e-178 S Nuclease-related domain
KKNCFHKG_01723 1.1e-18
KKNCFHKG_01724 2.2e-50
KKNCFHKG_01725 2.6e-169 czcD P COG1230 Co Zn Cd efflux system component
KKNCFHKG_01726 9e-209 T Osmosensitive K+ channel His kinase sensor domain
KKNCFHKG_01727 1.3e-99 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KKNCFHKG_01728 0.0 kdpB 3.6.3.12 P of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the
KKNCFHKG_01729 1.9e-303 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KKNCFHKG_01730 2.3e-83 L PFAM transposase IS4 family protein
KKNCFHKG_01731 2.5e-19 L PFAM transposase IS4 family protein
KKNCFHKG_01732 8.5e-14 ma_1747 S ABC transporter
KKNCFHKG_01733 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KKNCFHKG_01734 1e-292 M Glycosyltransferase like family 2
KKNCFHKG_01735 1.1e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
KKNCFHKG_01736 6.9e-181 mvaD 4.1.1.33 I GHMP kinases N terminal domain
KKNCFHKG_01737 1.4e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
KKNCFHKG_01738 9.7e-115 yhfK GM NmrA-like family
KKNCFHKG_01739 2.2e-31 csfB S Inhibitor of sigma-G Gin
KKNCFHKG_01740 3.6e-282 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KKNCFHKG_01741 2.3e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KKNCFHKG_01742 9.8e-55 yaaQ S protein conserved in bacteria
KKNCFHKG_01743 1.5e-71 yaaR S protein conserved in bacteria
KKNCFHKG_01744 8.9e-184 holB 2.7.7.7 L DNA polymerase III
KKNCFHKG_01745 1.7e-148 yaaT S stage 0 sporulation protein
KKNCFHKG_01746 3.3e-61 yabA L Involved in initiation control of chromosome replication
KKNCFHKG_01747 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
KKNCFHKG_01748 1.2e-48 yazA L endonuclease containing a URI domain
KKNCFHKG_01749 2.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KKNCFHKG_01750 4.7e-48 abrB K COG2002 Regulators of stationary sporulation gene expression
KKNCFHKG_01751 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKNCFHKG_01752 8e-148 tatD L hydrolase, TatD
KKNCFHKG_01753 1.1e-104 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KKNCFHKG_01754 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KKNCFHKG_01755 1.4e-161 yabG S peptidase
KKNCFHKG_01756 2.4e-37 veg S protein conserved in bacteria
KKNCFHKG_01757 1.9e-26 sspF S DNA topological change
KKNCFHKG_01758 7.3e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KKNCFHKG_01759 1.3e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KKNCFHKG_01760 1.2e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KKNCFHKG_01761 1.4e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KKNCFHKG_01763 2.5e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_01764 3.1e-19 L Transposase, IS605 OrfB family
KKNCFHKG_01765 1.6e-239 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKNCFHKG_01766 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKNCFHKG_01767 1.7e-108 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KKNCFHKG_01768 2.7e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KKNCFHKG_01769 5.7e-38 yabK S Peptide ABC transporter permease
KKNCFHKG_01770 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KKNCFHKG_01771 4.7e-91 spoVT K stage V sporulation protein
KKNCFHKG_01772 2.3e-274 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKNCFHKG_01773 1.4e-190 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KKNCFHKG_01774 3.1e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KKNCFHKG_01775 3e-50 yabP S Sporulation protein YabP
KKNCFHKG_01776 8e-106 yabQ S spore cortex biosynthesis protein
KKNCFHKG_01777 1.9e-60 divIC D Septum formation initiator
KKNCFHKG_01778 3.7e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KKNCFHKG_01780 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KKNCFHKG_01782 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
KKNCFHKG_01783 2.8e-166 KLT serine threonine protein kinase
KKNCFHKG_01784 8.9e-278 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KKNCFHKG_01785 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KKNCFHKG_01786 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKNCFHKG_01787 1.7e-159 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KKNCFHKG_01788 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KKNCFHKG_01789 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KKNCFHKG_01790 1.7e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KKNCFHKG_01791 3.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KKNCFHKG_01792 1.1e-97 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KKNCFHKG_01794 2.7e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KKNCFHKG_01795 4.5e-43 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KKNCFHKG_01796 1e-289 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KKNCFHKG_01797 6.4e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KKNCFHKG_01798 2.3e-111 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KKNCFHKG_01799 7.4e-43 atsK 1.14.11.17 Q Taurine catabolism dioxygenase TauD, TfdA family
KKNCFHKG_01801 6.5e-107 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KKNCFHKG_01802 9.3e-203 mmuP E Permease
KKNCFHKG_01803 8.9e-160 L Transposase IS4 family protein
KKNCFHKG_01804 1.8e-50 L Transposase IS4 family protein
KKNCFHKG_01805 1.3e-117 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKNCFHKG_01806 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KKNCFHKG_01807 7.8e-225 uraA F Xanthine uracil
KKNCFHKG_01808 1.2e-14 S Leucine-rich repeat (LRR) protein
KKNCFHKG_01809 5e-50 S Leucine-rich repeat (LRR) protein
KKNCFHKG_01810 1e-271 EGP Major facilitator Superfamily
KKNCFHKG_01813 4.9e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKNCFHKG_01814 4.9e-153 M Glycosyl transferase family 8
KKNCFHKG_01815 3.1e-240 yisQ V Mate efflux family protein
KKNCFHKG_01816 1.8e-220 pilM NU Pilus assembly protein
KKNCFHKG_01817 8.9e-96
KKNCFHKG_01818 4.7e-140 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KKNCFHKG_01819 3.3e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKNCFHKG_01820 2.9e-98 metI P COG2011 ABC-type metal ion transport system, permease component
KKNCFHKG_01821 2.1e-154 metQ M Belongs to the nlpA lipoprotein family
KKNCFHKG_01822 0.0 cstA T Carbon starvation protein
KKNCFHKG_01823 1.6e-207 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KKNCFHKG_01824 3e-128 thrE S Putative threonine/serine exporter
KKNCFHKG_01825 1e-70 S Threonine/Serine exporter, ThrE
KKNCFHKG_01826 3.5e-127 S Protein of unknown function (DUF1646)
KKNCFHKG_01827 0.0 asnO 6.3.5.4 E Asparagine synthase
KKNCFHKG_01828 2.9e-176 ywbI K Transcriptional regulator
KKNCFHKG_01829 2.3e-55 ywbH S LrgA family
KKNCFHKG_01830 3.8e-117 ywbG M effector of murein hydrolase
KKNCFHKG_01832 7.3e-115 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KKNCFHKG_01833 1.4e-77
KKNCFHKG_01834 4.4e-126 T Two component transcriptional regulator, winged helix family
KKNCFHKG_01835 4.2e-231 T His Kinase A (phosphoacceptor) domain
KKNCFHKG_01836 7.7e-14
KKNCFHKG_01837 3.2e-161 S Alpha/beta hydrolase of unknown function (DUF915)
KKNCFHKG_01838 3.4e-152 ybbH_2 K Transcriptional regulator
KKNCFHKG_01839 2.1e-230 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
KKNCFHKG_01840 0.0 recQ 3.6.4.12 L DNA helicase
KKNCFHKG_01841 9.8e-163 ycsE S hydrolases of the HAD superfamily
KKNCFHKG_01842 6.2e-128 bshB2 S deacetylase
KKNCFHKG_01843 5.7e-61 yojF S Protein of unknown function (DUF1806)
KKNCFHKG_01844 2.4e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKNCFHKG_01845 3e-165 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KKNCFHKG_01846 2.8e-111 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KKNCFHKG_01847 7e-78 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KKNCFHKG_01848 2e-225 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKNCFHKG_01849 9e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KKNCFHKG_01850 4.3e-141 yycI S protein conserved in bacteria
KKNCFHKG_01851 8.3e-243 yycH S protein conserved in bacteria
KKNCFHKG_01852 0.0 vicK 2.7.13.3 T Histidine kinase
KKNCFHKG_01853 1.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_01857 1.9e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KKNCFHKG_01858 1.4e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KKNCFHKG_01859 1.2e-71 rplI J binds to the 23S rRNA
KKNCFHKG_01860 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KKNCFHKG_01861 4.6e-158 yybS S membrane
KKNCFHKG_01862 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KKNCFHKG_01863 2.2e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KKNCFHKG_01864 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KKNCFHKG_01865 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KKNCFHKG_01866 8.9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KKNCFHKG_01867 2.3e-116 ribE 2.5.1.9 H Riboflavin synthase
KKNCFHKG_01868 8.9e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKNCFHKG_01869 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KKNCFHKG_01870 1.1e-32 yyzM S protein conserved in bacteria
KKNCFHKG_01871 1.5e-136 ykuT M Mechanosensitive ion channel
KKNCFHKG_01872 1.5e-112 yyaC S Sporulation protein YyaC
KKNCFHKG_01873 2.3e-117 ydfK S Protein of unknown function (DUF554)
KKNCFHKG_01874 1.5e-150 spo0J K Belongs to the ParB family
KKNCFHKG_01875 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
KKNCFHKG_01876 3.5e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KKNCFHKG_01877 2.5e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KKNCFHKG_01878 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KKNCFHKG_01879 3.4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KKNCFHKG_01880 5.9e-109 jag S single-stranded nucleic acid binding R3H
KKNCFHKG_01881 3.2e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKNCFHKG_01882 4.2e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KKNCFHKG_01883 9e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKNCFHKG_01884 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KKNCFHKG_01885 4.5e-32 yaaA S S4 domain
KKNCFHKG_01886 7.8e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KKNCFHKG_01887 6.2e-10 yaaB S Domain of unknown function (DUF370)
KKNCFHKG_01888 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKNCFHKG_01889 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKNCFHKG_01890 2.2e-196 M1-161 T HD domain
KKNCFHKG_01891 9.1e-89 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KKNCFHKG_01892 2e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KKNCFHKG_01893 3e-51 ylaH S YlaH-like protein
KKNCFHKG_01894 0.0 typA T GTP-binding protein TypA
KKNCFHKG_01895 6e-25 S Family of unknown function (DUF5325)
KKNCFHKG_01896 1.3e-145 suhB 3.1.3.25 G Inositol monophosphatase
KKNCFHKG_01897 1.4e-24
KKNCFHKG_01898 2.9e-116 yktB S Belongs to the UPF0637 family
KKNCFHKG_01899 6.1e-45 yktA S Belongs to the UPF0223 family
KKNCFHKG_01901 6.1e-274 speA 4.1.1.19 E Arginine
KKNCFHKG_01903 1.6e-33
KKNCFHKG_01904 6.3e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKNCFHKG_01905 1e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKNCFHKG_01906 4.5e-180 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKNCFHKG_01907 1.2e-202 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKNCFHKG_01909 1.2e-29 ykzG S Belongs to the UPF0356 family
KKNCFHKG_01910 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKNCFHKG_01911 1.8e-18 S YhfH-like protein
KKNCFHKG_01912 3.6e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KKNCFHKG_01913 1.2e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KKNCFHKG_01914 2.3e-156 ccpC K Transcriptional regulator
KKNCFHKG_01915 6.5e-78 ykuL S CBS domain
KKNCFHKG_01916 5.8e-39 ykuJ S protein conserved in bacteria
KKNCFHKG_01917 4.3e-161 3.5.1.4 C Acetamidase
KKNCFHKG_01918 2.1e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKNCFHKG_01919 1e-31
KKNCFHKG_01920 1e-32 T Diguanylate cyclase
KKNCFHKG_01921 3e-16 T Diguanylate cyclase
KKNCFHKG_01922 0.0 ydgH S drug exporters of the RND superfamily
KKNCFHKG_01923 2.6e-85 ykyB S YkyB-like protein
KKNCFHKG_01924 6.4e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
KKNCFHKG_01925 4.4e-219 patA 2.6.1.1 E Aminotransferase
KKNCFHKG_01926 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KKNCFHKG_01927 6.2e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKNCFHKG_01928 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KKNCFHKG_01929 3.2e-40 ptsH G phosphocarrier protein HPr
KKNCFHKG_01930 5e-26
KKNCFHKG_01931 4.2e-26 ykvS S protein conserved in bacteria
KKNCFHKG_01932 7.3e-104 S Abortive infection protein
KKNCFHKG_01933 1.1e-179 ykvI S membrane
KKNCFHKG_01934 0.0 clpE O Belongs to the ClpA ClpB family
KKNCFHKG_01936 4.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
KKNCFHKG_01937 4e-78 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KKNCFHKG_01938 5.1e-284 kinE 2.7.13.3 T Histidine kinase
KKNCFHKG_01940 4.3e-19 S Stage 0 Sporulation Regulatory protein
KKNCFHKG_01941 2.8e-28 sspD S small acid-soluble spore protein
KKNCFHKG_01942 8.6e-129 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KKNCFHKG_01943 3.1e-78
KKNCFHKG_01944 1.5e-43 ylaN S Belongs to the UPF0358 family
KKNCFHKG_01945 8.8e-218 ftsW D Belongs to the SEDS family
KKNCFHKG_01946 3.6e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KKNCFHKG_01947 1.6e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KKNCFHKG_01948 4.9e-196 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KKNCFHKG_01949 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKNCFHKG_01950 2.1e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KKNCFHKG_01951 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KKNCFHKG_01952 1.7e-168 ctaG S cytochrome c oxidase
KKNCFHKG_01953 9.6e-64 ylbA S YugN-like family
KKNCFHKG_01954 2.3e-167 ylbC S protein with SCP PR1 domains
KKNCFHKG_01955 1.7e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
KKNCFHKG_01956 2e-70 ylbD S Putative coat protein
KKNCFHKG_01957 7.9e-38 ylbE S YlbE-like protein
KKNCFHKG_01958 3.3e-62
KKNCFHKG_01959 2.8e-73 ylbF S Belongs to the UPF0342 family
KKNCFHKG_01960 4.1e-45 ylbG S UPF0298 protein
KKNCFHKG_01961 7.7e-67 S Methylthioribose kinase
KKNCFHKG_01962 2.3e-105 rsmD 2.1.1.171 L Methyltransferase
KKNCFHKG_01963 6.6e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KKNCFHKG_01964 5.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
KKNCFHKG_01965 7.6e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KKNCFHKG_01966 6.5e-193 ylbL T Belongs to the peptidase S16 family
KKNCFHKG_01967 8.2e-224 ylbM S Belongs to the UPF0348 family
KKNCFHKG_01968 1.2e-93 yceD S metal-binding, possibly nucleic acid-binding protein
KKNCFHKG_01969 1.1e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KKNCFHKG_01970 1.6e-80 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KKNCFHKG_01971 2.3e-92 ylbP K n-acetyltransferase
KKNCFHKG_01972 1.1e-158 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KKNCFHKG_01973 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KKNCFHKG_01974 1.4e-77 mraZ K Belongs to the MraZ family
KKNCFHKG_01975 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KKNCFHKG_01976 1.7e-39 ftsL D Essential cell division protein
KKNCFHKG_01977 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KKNCFHKG_01978 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KKNCFHKG_01979 4.8e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KKNCFHKG_01980 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KKNCFHKG_01981 2.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKNCFHKG_01982 1.3e-257 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKNCFHKG_01983 7.7e-189 spoVE D Belongs to the SEDS family
KKNCFHKG_01984 7.7e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKNCFHKG_01985 1.1e-117 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KKNCFHKG_01987 6.4e-219 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KKNCFHKG_01988 3.6e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KKNCFHKG_01989 7.3e-164 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KKNCFHKG_01990 3.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_01991 3.7e-137 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_01992 2.4e-99 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KKNCFHKG_01994 1.6e-101 P Integral membrane protein TerC family
KKNCFHKG_01995 7.8e-304 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KKNCFHKG_01996 7e-23 S Uncharacterized small protein (DUF2292)
KKNCFHKG_01997 3.3e-08 ssuE 1.5.1.38 S FMN reductase
KKNCFHKG_01998 4.2e-77 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KKNCFHKG_01999 8.5e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KKNCFHKG_02000 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KKNCFHKG_02001 4e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KKNCFHKG_02002 1.4e-110 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKNCFHKG_02003 1.4e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KKNCFHKG_02004 1.1e-233 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KKNCFHKG_02005 5.7e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KKNCFHKG_02006 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KKNCFHKG_02007 1.1e-207 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KKNCFHKG_02008 1.4e-224 pbuO_1 S permease
KKNCFHKG_02009 3e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KKNCFHKG_02010 1.5e-164 S Protein of unknown function (DUF979)
KKNCFHKG_02011 6.5e-117 S Protein of unknown function (DUF969)
KKNCFHKG_02012 2.2e-137 ycsF S Belongs to the UPF0271 (lamB) family
KKNCFHKG_02013 1.6e-185 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KKNCFHKG_02014 1.2e-131 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
KKNCFHKG_02015 1.7e-213 EGP Major facilitator Superfamily
KKNCFHKG_02016 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
KKNCFHKG_02017 5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKNCFHKG_02018 5.8e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
KKNCFHKG_02019 6.7e-131 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KKNCFHKG_02020 5e-210 hipO3 3.5.1.47 S amidohydrolase
KKNCFHKG_02021 0.0 htpG O Molecular chaperone. Has ATPase activity
KKNCFHKG_02022 8.2e-183 M FFAT motif binding
KKNCFHKG_02023 9.1e-56 I Domain of unknown function (DUF4430)
KKNCFHKG_02024 4.2e-90 S Psort location CytoplasmicMembrane, score
KKNCFHKG_02025 1.8e-115 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
KKNCFHKG_02026 4.3e-211 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KKNCFHKG_02027 1.6e-29 S Nucleotidyltransferase domain
KKNCFHKG_02028 3.8e-190 adhP 1.1.1.1 C alcohol dehydrogenase
KKNCFHKG_02030 1.1e-149 S LXG domain of WXG superfamily
KKNCFHKG_02031 4.4e-41 S LXG domain of WXG superfamily
KKNCFHKG_02034 3.8e-140 S Protein of unknown function
KKNCFHKG_02035 1.1e-189 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KKNCFHKG_02036 1.7e-197 glvC 2.7.1.199, 2.7.1.208 G pts system
KKNCFHKG_02037 3.8e-33 glvR K Helix-turn-helix domain, rpiR family
KKNCFHKG_02039 1.8e-41 nagE 2.7.1.193, 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KKNCFHKG_02040 1.1e-118 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KKNCFHKG_02041 2.4e-90 yebE S UPF0316 protein
KKNCFHKG_02042 2.9e-31 yebG S NETI protein
KKNCFHKG_02043 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KKNCFHKG_02044 4.6e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KKNCFHKG_02045 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KKNCFHKG_02046 2.5e-124 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KKNCFHKG_02047 7.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKNCFHKG_02048 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKNCFHKG_02049 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKNCFHKG_02050 4.2e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KKNCFHKG_02051 2.1e-191 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KKNCFHKG_02052 4.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KKNCFHKG_02053 2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KKNCFHKG_02054 1.6e-230 purD 6.3.4.13 F Belongs to the GARS family
KKNCFHKG_02055 3.2e-36 S Protein of unknown function (DUF2892)
KKNCFHKG_02056 0.0 yerA 3.5.4.2 F adenine deaminase
KKNCFHKG_02057 4.2e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
KKNCFHKG_02058 2.2e-54 yerC S protein conserved in bacteria
KKNCFHKG_02059 4.8e-128 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KKNCFHKG_02060 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KKNCFHKG_02061 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KKNCFHKG_02062 1.3e-215 camS S COG4851 Protein involved in sex pheromone biosynthesis
KKNCFHKG_02063 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
KKNCFHKG_02064 1.5e-244 aceA 4.1.3.1 C Isocitrate lyase
KKNCFHKG_02066 7.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKNCFHKG_02067 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KKNCFHKG_02068 3.3e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKNCFHKG_02071 5.2e-150 Q N-acetyltransferase
KKNCFHKG_02072 3.5e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KKNCFHKG_02073 9.5e-267 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKNCFHKG_02074 4.4e-242 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKNCFHKG_02075 1.8e-81
KKNCFHKG_02076 6.3e-132 ypmR1 E G-D-S-L family
KKNCFHKG_02077 5.6e-169 bcrA V ABC transporter, ATP-binding protein
KKNCFHKG_02078 5.7e-175 bcrB S ABC transporter (permease)
KKNCFHKG_02079 6.4e-88
KKNCFHKG_02080 7.4e-95 1.5.1.38 S FMN reductase
KKNCFHKG_02081 2.1e-145 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KKNCFHKG_02082 0.0 pflB 2.3.1.54 C formate acetyltransferase
KKNCFHKG_02085 3.5e-149 focA P Formate/nitrite transporter
KKNCFHKG_02086 1.8e-22 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKNCFHKG_02087 6.2e-66 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKNCFHKG_02088 4.2e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
KKNCFHKG_02089 5e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KKNCFHKG_02090 2.4e-83 S Rubrerythrin
KKNCFHKG_02091 4.6e-166 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KKNCFHKG_02092 8.2e-103 yvbG U UPF0056 membrane protein
KKNCFHKG_02093 6e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KKNCFHKG_02094 1.1e-161 yhbB S Putative amidase domain
KKNCFHKG_02095 2e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KKNCFHKG_02096 0.0 prkA T Ser protein kinase
KKNCFHKG_02097 8.1e-221 yhbH S Belongs to the UPF0229 family
KKNCFHKG_02099 1.9e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
KKNCFHKG_02100 3.4e-175 pit P phosphate transporter
KKNCFHKG_02101 5.6e-112 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KKNCFHKG_02102 1.2e-10 yhcU S Family of unknown function (DUF5365)
KKNCFHKG_02103 3.9e-66 yhcU S Family of unknown function (DUF5365)
KKNCFHKG_02104 5.8e-88 bdbA CO Thioredoxin
KKNCFHKG_02105 2.1e-73 bdbC O Required for disulfide bond formation in some proteins
KKNCFHKG_02106 1.6e-134 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
KKNCFHKG_02107 4.1e-181 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KKNCFHKG_02108 6.9e-275 ycgB S Stage V sporulation protein R
KKNCFHKG_02110 1.8e-46 yhdB S YhdB-like protein
KKNCFHKG_02111 2.5e-183 corA P Mediates influx of magnesium ions
KKNCFHKG_02112 6e-126 S Peptidase C26
KKNCFHKG_02113 4.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKNCFHKG_02114 6.5e-168 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKNCFHKG_02115 4.6e-188 dppD P Belongs to the ABC transporter superfamily
KKNCFHKG_02116 0.0 dppE E ABC transporter substrate-binding protein
KKNCFHKG_02117 1.5e-177 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KKNCFHKG_02118 6.9e-192 ykfD E Belongs to the ABC transporter superfamily
KKNCFHKG_02120 9.6e-86 uspF T Universal stress protein
KKNCFHKG_02121 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKNCFHKG_02123 3.4e-163 ygxA S Nucleotidyltransferase-like
KKNCFHKG_02124 2.8e-55 ygzB S UPF0295 protein
KKNCFHKG_02125 2.9e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KKNCFHKG_02126 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KKNCFHKG_02127 1.5e-163 alsR K Transcriptional regulator
KKNCFHKG_02128 5.4e-87 iprA K Transcriptional regulator
KKNCFHKG_02130 2.9e-81 perR P Belongs to the Fur family
KKNCFHKG_02131 2.3e-101 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
KKNCFHKG_02132 3.4e-65 P Ion transport
KKNCFHKG_02133 5.6e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KKNCFHKG_02134 1.2e-37 yqhV S Protein of unknown function (DUF2619)
KKNCFHKG_02135 3.2e-187 ygaE S Membrane
KKNCFHKG_02136 1.2e-147 K transcriptional
KKNCFHKG_02137 1.6e-250 sacX 2.7.1.201, 2.7.1.211 G phosphotransferase system
KKNCFHKG_02138 6.8e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KKNCFHKG_02139 2.6e-205 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KKNCFHKG_02140 0.0 ygaD V ABC transporter
KKNCFHKG_02141 5.3e-103 ygaC J Belongs to the UPF0374 family
KKNCFHKG_02142 1.3e-35 ygaB S YgaB-like protein
KKNCFHKG_02143 1.7e-08 sspE S Small, acid-soluble spore protein, gamma-type
KKNCFHKG_02144 7.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKNCFHKG_02145 4.9e-165 gltC K Transcriptional regulator
KKNCFHKG_02146 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KKNCFHKG_02148 1.4e-278 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KKNCFHKG_02149 8.8e-31
KKNCFHKG_02150 3.1e-198 mutY L A G-specific
KKNCFHKG_02151 4.1e-181 yfhP S membrane-bound metal-dependent
KKNCFHKG_02152 4.2e-19 sspK S reproduction
KKNCFHKG_02153 4.5e-49 yfhH S Protein of unknown function (DUF1811)
KKNCFHKG_02154 2.4e-131 recX 2.4.1.337 GT4 S Modulates RecA activity
KKNCFHKG_02156 3.8e-24 yfhD S YfhD-like protein
KKNCFHKG_02157 6.9e-139 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KKNCFHKG_02159 1.6e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KKNCFHKG_02160 2.8e-247 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
KKNCFHKG_02161 2.2e-182 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KKNCFHKG_02162 1.5e-106 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KKNCFHKG_02163 4.7e-260 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KKNCFHKG_02164 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KKNCFHKG_02166 5.5e-29 yodI
KKNCFHKG_02167 5.9e-120 yjaZ O Zn-dependent protease
KKNCFHKG_02168 2.5e-101 yodH Q Methyltransferase
KKNCFHKG_02169 8.5e-21 S PD-(D/E)XK nuclease family transposase
KKNCFHKG_02170 2.1e-111 S PD-(D/E)XK nuclease family transposase
KKNCFHKG_02171 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KKNCFHKG_02172 1.9e-21 ygiM N Bacterial SH3 domain
KKNCFHKG_02173 1.7e-197 L High confidence in function and specificity
KKNCFHKG_02174 3.5e-68 G PTS system fructose IIA component
KKNCFHKG_02175 1.3e-143 G PTS system mannose/fructose/sorbose family IID component
KKNCFHKG_02176 5.9e-138 agaC G PTS system sorbose-specific iic component
KKNCFHKG_02177 9.6e-80 agaB 2.7.1.191 G PTS system sorbose subfamily IIB component
KKNCFHKG_02178 1.5e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KKNCFHKG_02179 4.6e-129 K UTRA
KKNCFHKG_02180 3.8e-96 puuR_2 K Cupin domain
KKNCFHKG_02181 0.0 oplaH 3.5.2.14, 3.5.2.9 EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
KKNCFHKG_02182 0.0 3.5.2.14 EQ COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
KKNCFHKG_02183 3.7e-249 F Permease for cytosine/purines, uracil, thiamine, allantoin
KKNCFHKG_02184 0.0 K PTS system fructose IIA component
KKNCFHKG_02185 2.6e-95 K PRD domain
KKNCFHKG_02186 1.5e-71 2.7.1.191 G PTS system fructose IIA component
KKNCFHKG_02187 2.1e-42 2.7.1.191 G PTS system mannose fructose sorbose family
KKNCFHKG_02188 5.7e-133 G PTS system sorbose-specific iic component
KKNCFHKG_02189 6.1e-143 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KKNCFHKG_02190 1.2e-169 M SIS domain
KKNCFHKG_02191 7.6e-12 M SIS domain
KKNCFHKG_02192 1.3e-170 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
KKNCFHKG_02193 1.2e-35 2.7.1.197, 2.7.1.200, 2.7.1.202 G PTS galactitol transporter subunit IIA
KKNCFHKG_02194 4.1e-30 sgcB 2.7.1.200 G to PTS system galactitol-specific enzyme IIB component
KKNCFHKG_02195 9.8e-197 G PTS system sugar-specific permease component
KKNCFHKG_02197 4e-72 2.7.1.11, 2.7.1.56 F pfkB family carbohydrate kinase
KKNCFHKG_02198 7.9e-85 4.1.2.17, 4.1.2.19 G Class II Aldolase and Adducin N-terminal domain
KKNCFHKG_02199 5.7e-284 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KKNCFHKG_02200 1.8e-19 S transposase or invertase
KKNCFHKG_02202 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KKNCFHKG_02203 4.3e-40 crh G Phosphocarrier protein Chr
KKNCFHKG_02204 5.2e-173 whiA K May be required for sporulation
KKNCFHKG_02205 8.5e-179 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KKNCFHKG_02206 3.4e-163 rapZ S Displays ATPase and GTPase activities
KKNCFHKG_02207 5.1e-86 yvcI 3.6.1.55 F Nudix hydrolase
KKNCFHKG_02208 3.1e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KKNCFHKG_02209 1.3e-250 S COG0457 FOG TPR repeat
KKNCFHKG_02210 5.2e-71 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KKNCFHKG_02211 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KKNCFHKG_02212 3.5e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKNCFHKG_02213 1.7e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KKNCFHKG_02214 3.5e-31 yvlD S Membrane
KKNCFHKG_02215 1.7e-170 yvlB S Putative adhesin
KKNCFHKG_02216 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KKNCFHKG_02217 4.5e-146 tagG GM Transport permease protein
KKNCFHKG_02218 2e-230 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKNCFHKG_02219 4.9e-229 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKNCFHKG_02220 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KKNCFHKG_02221 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KKNCFHKG_02222 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KKNCFHKG_02223 3.6e-09 S Uncharacterized conserved protein (DUF2164)
KKNCFHKG_02224 1.2e-33 csbA S protein conserved in bacteria
KKNCFHKG_02225 1.6e-117 yfbR S HD containing hydrolase-like enzyme
KKNCFHKG_02226 2.1e-49 S EamA-like transporter family
KKNCFHKG_02227 2.1e-55 P EamA-like transporter family
KKNCFHKG_02228 0.0
KKNCFHKG_02229 3.9e-173 M Glycosyltransferase like family 2
KKNCFHKG_02230 5.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKNCFHKG_02231 1.4e-153 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKNCFHKG_02232 6.9e-156 pstA P Phosphate transport system permease
KKNCFHKG_02233 1.6e-158 pstC P probably responsible for the translocation of the substrate across the membrane
KKNCFHKG_02234 1.2e-160 pstS P Phosphate
KKNCFHKG_02235 3.3e-261 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KKNCFHKG_02236 1.4e-40 fdxA C 4Fe-4S binding domain
KKNCFHKG_02237 2.5e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_02238 1.5e-269 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KKNCFHKG_02239 2.7e-182 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KKNCFHKG_02240 1.1e-197 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KKNCFHKG_02241 7.5e-94 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
KKNCFHKG_02243 1.8e-238 yhfA C membrane
KKNCFHKG_02244 3.7e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KKNCFHKG_02245 7.2e-220 ecsB U ABC transporter
KKNCFHKG_02246 1.6e-137 ecsA V transporter (ATP-binding protein)
KKNCFHKG_02247 4.1e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KKNCFHKG_02248 1.9e-84 trpP S Tryptophan transporter TrpP
KKNCFHKG_02249 2.1e-18 yhaH S YtxH-like protein
KKNCFHKG_02250 1.2e-103 hpr K Negative regulator of protease production and sporulation
KKNCFHKG_02251 1.1e-53 yhaI S Protein of unknown function (DUF1878)
KKNCFHKG_02254 3.1e-148 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KKNCFHKG_02255 3e-27 yhaL S Sporulation protein YhaL
KKNCFHKG_02256 1.1e-178 yhaM L Shows a 3'-5' exoribonuclease activity
KKNCFHKG_02257 0.0 L AAA domain
KKNCFHKG_02258 2.8e-240 yhaO L DNA repair exonuclease
KKNCFHKG_02259 6.9e-153 ycgQ S membrane
KKNCFHKG_02260 3.3e-145 ycgR S permeases
KKNCFHKG_02261 8.1e-121 P Integral membrane protein TerC family
KKNCFHKG_02262 4.9e-27 S YhzD-like protein
KKNCFHKG_02263 2.9e-137 yhaR 5.3.3.18 I enoyl-CoA hydratase
KKNCFHKG_02264 3e-159 yhaX S hydrolases of the HAD superfamily
KKNCFHKG_02265 6.1e-55 yheA S Belongs to the UPF0342 family
KKNCFHKG_02266 9.1e-209 yheB S Belongs to the UPF0754 family
KKNCFHKG_02267 1e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KKNCFHKG_02268 9.3e-211 yheC HJ YheC/D like ATP-grasp
KKNCFHKG_02269 5.5e-269 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KKNCFHKG_02270 4.1e-228 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
KKNCFHKG_02271 6.8e-167 lrp QT PucR C-terminal helix-turn-helix domain
KKNCFHKG_02272 5e-204 msmK P Belongs to the ABC transporter superfamily
KKNCFHKG_02273 3.4e-29 sspB S spore protein
KKNCFHKG_02274 2.7e-263 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KKNCFHKG_02275 1.3e-232 pgaC GT2 M N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity
KKNCFHKG_02276 1.9e-47 icaD
KKNCFHKG_02277 5.4e-147 icaB G Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide
KKNCFHKG_02278 7.3e-173 icaC G transferase activity, transferring acyl groups other than amino-acyl groups
KKNCFHKG_02279 6.1e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
KKNCFHKG_02280 1.4e-228 yumB 1.6.99.3 C NADH dehydrogenase
KKNCFHKG_02281 1.2e-46 yuiB S Putative membrane protein
KKNCFHKG_02282 6.4e-108 yuiC S protein conserved in bacteria
KKNCFHKG_02283 6.3e-299 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KKNCFHKG_02285 3.5e-294 gerKA EG Spore germination protein
KKNCFHKG_02286 6e-227 gerKC S spore germination
KKNCFHKG_02287 1.7e-191 E Spore germination protein
KKNCFHKG_02289 2.8e-55 yuzC
KKNCFHKG_02290 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
KKNCFHKG_02291 8.8e-194 yuxJ EGP Major facilitator Superfamily
KKNCFHKG_02292 1.5e-67 kapB G Kinase associated protein B
KKNCFHKG_02293 2.7e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KKNCFHKG_02295 6e-238 S protein conserved in bacteria
KKNCFHKG_02296 9.9e-160 dkgB S Aldo/keto reductase family
KKNCFHKG_02297 3.6e-165 S reductase
KKNCFHKG_02298 8e-196 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KKNCFHKG_02299 5.9e-29 K Helix-turn-helix XRE-family like proteins
KKNCFHKG_02300 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KKNCFHKG_02301 4e-86 K Bacterial transcription activator, effector binding domain
KKNCFHKG_02302 5.1e-34 yuzA S Domain of unknown function (DUF378)
KKNCFHKG_02303 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
KKNCFHKG_02304 1.9e-181 yugO P COG1226 Kef-type K transport systems
KKNCFHKG_02307 3.7e-168 4.3.1.12 E ornithine cyclodeaminase
KKNCFHKG_02308 5.9e-277 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKNCFHKG_02309 9.9e-227 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
KKNCFHKG_02310 6.1e-221 solA 1.5.3.1 E FAD dependent oxidoreductase
KKNCFHKG_02311 9.6e-72 yuiD S protein conserved in bacteria
KKNCFHKG_02312 3e-133 L PFAM transposase IS4 family protein
KKNCFHKG_02313 5.4e-113 L PFAM transposase IS4 family protein
KKNCFHKG_02315 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KKNCFHKG_02316 2.7e-74 cueR K transcriptional
KKNCFHKG_02317 6.1e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KKNCFHKG_02318 2.1e-148
KKNCFHKG_02319 5.7e-197 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KKNCFHKG_02320 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KKNCFHKG_02321 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KKNCFHKG_02322 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KKNCFHKG_02323 2.8e-146 malA S Protein of unknown function (DUF1189)
KKNCFHKG_02324 6.7e-156 malD P transport
KKNCFHKG_02325 3.3e-239 malC P COG1175 ABC-type sugar transport systems, permease components
KKNCFHKG_02326 4.4e-236 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KKNCFHKG_02327 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KKNCFHKG_02328 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KKNCFHKG_02329 6.1e-174 yvdE K Transcriptional regulator
KKNCFHKG_02330 3.3e-121 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KKNCFHKG_02331 5.5e-107 E Lysine exporter protein LysE YggA
KKNCFHKG_02332 9.1e-114 L COG2826 Transposase and inactivated derivatives, IS30 family
KKNCFHKG_02333 8.4e-254 pgi 5.3.1.9 G Belongs to the GPI family
KKNCFHKG_02334 6e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KKNCFHKG_02335 1.4e-259 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KKNCFHKG_02336 3.7e-50 hxlR K transcriptional
KKNCFHKG_02337 6.4e-87 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KKNCFHKG_02338 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
KKNCFHKG_02339 7.8e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KKNCFHKG_02340 2.1e-192 S AI-2E family transporter
KKNCFHKG_02341 1.7e-109 lmrB EGP the major facilitator superfamily
KKNCFHKG_02342 1.3e-222 EGP Major facilitator Superfamily
KKNCFHKG_02343 1.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKNCFHKG_02344 1.1e-23 S double-stranded DNA endodeoxyribonuclease activity
KKNCFHKG_02346 3.8e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KKNCFHKG_02347 2.2e-14 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KKNCFHKG_02348 9.8e-208 L Transposase IS4 family protein
KKNCFHKG_02349 1.4e-156 S Nuclease-related domain
KKNCFHKG_02351 3.2e-110 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKNCFHKG_02352 1.1e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KKNCFHKG_02353 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KKNCFHKG_02354 2.8e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KKNCFHKG_02355 0.0 carB 6.3.5.5 F Belongs to the CarB family
KKNCFHKG_02356 6.5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKNCFHKG_02357 1.1e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KKNCFHKG_02358 3.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KKNCFHKG_02359 9.7e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKNCFHKG_02360 7.9e-179 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKNCFHKG_02361 1.3e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKNCFHKG_02363 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKNCFHKG_02364 2.5e-65 divIVA D Cell division initiation protein
KKNCFHKG_02365 3.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KKNCFHKG_02366 1.4e-38 yggT S membrane
KKNCFHKG_02367 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KKNCFHKG_02368 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KKNCFHKG_02369 8.2e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KKNCFHKG_02370 2.6e-73 yocH CBM50 M 3D domain
KKNCFHKG_02371 1.5e-43 ylmC S sporulation protein
KKNCFHKG_02372 9.4e-68 L COG2801 Transposase and inactivated derivatives
KKNCFHKG_02373 2.8e-34 S Protein of unknown function (DUF2971)
KKNCFHKG_02374 2.9e-17 L Transposase, IS4 family protein
KKNCFHKG_02375 5.6e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KKNCFHKG_02376 3.8e-135 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KKNCFHKG_02377 1.1e-87 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KKNCFHKG_02378 2.2e-146 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KKNCFHKG_02380 1.2e-160 S polysaccharide biosynthetic process
KKNCFHKG_02381 1.3e-38 L Transposase, IS4 family protein
KKNCFHKG_02382 1.7e-180 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
KKNCFHKG_02383 8.7e-12 3.2.1.15 M Right handed beta helix region
KKNCFHKG_02384 1e-69 J Glycosyl transferase family 2
KKNCFHKG_02386 1.4e-89 cps4F 2.4.1.306 GT4 M Glycosyl transferase 4-like
KKNCFHKG_02387 1.2e-23 M Glycosyl transferases group 1
KKNCFHKG_02388 3.9e-90 cpsE M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KKNCFHKG_02389 4.7e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KKNCFHKG_02390 1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KKNCFHKG_02391 1.3e-110 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KKNCFHKG_02392 1.1e-122 ywqC M biosynthesis protein
KKNCFHKG_02393 4.7e-151 E lipolytic protein G-D-S-L family
KKNCFHKG_02394 8.4e-97 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
KKNCFHKG_02395 4.3e-88 K ComK protein
KKNCFHKG_02397 1.2e-09 csbD S Belongs to the UPF0337 (CsbD) family
KKNCFHKG_02398 0.0 metH 2.1.1.13 E Methionine synthase
KKNCFHKG_02399 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KKNCFHKG_02400 1.3e-43 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KKNCFHKG_02402 7.7e-14 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KKNCFHKG_02403 2e-92 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KKNCFHKG_02404 1.1e-40 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KKNCFHKG_02405 1.3e-111 kstR2_2 K Transcriptional regulator
KKNCFHKG_02406 3.2e-214 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KKNCFHKG_02407 1e-207 mmgC I acyl-CoA dehydrogenase
KKNCFHKG_02408 2.9e-218 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
KKNCFHKG_02409 0.0 fadF C COG0247 Fe-S oxidoreductase
KKNCFHKG_02410 9.3e-212 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KKNCFHKG_02411 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KKNCFHKG_02412 6.7e-75 ywiB S Domain of unknown function (DUF1934)
KKNCFHKG_02413 4.1e-169 speB 3.5.3.11 E Belongs to the arginase family
KKNCFHKG_02414 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKNCFHKG_02415 1.7e-93 ywhD S YwhD family
KKNCFHKG_02416 7.8e-120 ywhC S Peptidase M50
KKNCFHKG_02417 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KKNCFHKG_02418 6e-91 ywgA 2.1.1.72, 3.1.21.3
KKNCFHKG_02419 6.1e-257 ywfO S COG1078 HD superfamily phosphohydrolases
KKNCFHKG_02420 8.2e-99 rsfA S Transcriptional regulator
KKNCFHKG_02421 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KKNCFHKG_02422 3.9e-176 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KKNCFHKG_02423 9.5e-146 ywfI C May function as heme-dependent peroxidase
KKNCFHKG_02424 3.7e-73 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KKNCFHKG_02425 2.2e-55 ywdK S small membrane protein
KKNCFHKG_02426 7.2e-37 S Family of unknown function (DUF5327)
KKNCFHKG_02427 6.4e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKNCFHKG_02428 1.1e-53 S Heat induced stress protein YflT
KKNCFHKG_02429 1.9e-31
KKNCFHKG_02430 1.8e-46
KKNCFHKG_02431 4.3e-161 L PFAM transposase, IS4 family protein
KKNCFHKG_02432 3.9e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKNCFHKG_02433 4.1e-165 mcpA NT Chemotaxis
KKNCFHKG_02434 3.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KKNCFHKG_02435 3.7e-94 ywlG S Belongs to the UPF0340 family
KKNCFHKG_02436 5.4e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKNCFHKG_02437 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KKNCFHKG_02438 8e-53 atpI S ATP synthase I chain
KKNCFHKG_02439 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
KKNCFHKG_02440 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKNCFHKG_02441 1.3e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKNCFHKG_02442 4.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKNCFHKG_02443 5.9e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKNCFHKG_02444 4.7e-149 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KKNCFHKG_02445 4.5e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KKNCFHKG_02446 1.8e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KKNCFHKG_02447 6.8e-34 ywzB S membrane
KKNCFHKG_02448 3.3e-135 ywmB S TATA-box binding
KKNCFHKG_02449 4.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKNCFHKG_02450 3.1e-184 spoIID D Stage II sporulation protein D
KKNCFHKG_02451 4.1e-128 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KKNCFHKG_02452 6.5e-41 spoIIID K Stage III sporulation protein D
KKNCFHKG_02453 1.9e-178 mbl D Rod shape-determining protein
KKNCFHKG_02454 1.1e-144 flhO N flagellar basal body
KKNCFHKG_02455 1.9e-139 flhP N flagellar basal body
KKNCFHKG_02456 8.7e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KKNCFHKG_02458 3.3e-64 ssbB L Single-stranded DNA-binding protein
KKNCFHKG_02459 1.9e-71 ywpF S YwpF-like protein
KKNCFHKG_02460 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KKNCFHKG_02461 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
KKNCFHKG_02462 3.6e-271 L RNA-directed DNA polymerase (reverse transcriptase)
KKNCFHKG_02463 1.1e-10 S double-stranded DNA endodeoxyribonuclease activity
KKNCFHKG_02464 4.5e-132 VVA0018 T Histidine kinase
KKNCFHKG_02465 4.7e-123 T helix_turn_helix, arabinose operon control protein
KKNCFHKG_02466 6.3e-07 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKNCFHKG_02467 3.5e-163 3.5.1.4 C Acetamidase
KKNCFHKG_02468 1.2e-223 puuP_1 E Amino acid permease
KKNCFHKG_02469 1.1e-12 S Zinc-ribbon containing domain
KKNCFHKG_02470 2.4e-298 yvfH C L-lactate permease
KKNCFHKG_02471 4.2e-119 yvfI K COG2186 Transcriptional regulators
KKNCFHKG_02472 4.4e-230 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKNCFHKG_02473 2.3e-60
KKNCFHKG_02475 3.3e-175 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KKNCFHKG_02476 3.6e-209 EGP Major facilitator Superfamily
KKNCFHKG_02478 2.2e-16 S YvrJ protein family
KKNCFHKG_02479 9.8e-11 S Protein of unknown function (DUF2922)
KKNCFHKG_02480 2.6e-11 S Protein of unknown function (DUF1659)
KKNCFHKG_02481 0.0 O Belongs to the peptidase S8 family
KKNCFHKG_02482 7.5e-223 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KKNCFHKG_02483 1.7e-27 licA 2.7.1.196, 2.7.1.205 G PTS cellobiose transporter subunit IIA
KKNCFHKG_02484 3.2e-73 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KKNCFHKG_02485 1.5e-146 yokF 3.1.31.1 L RNA catabolic process
KKNCFHKG_02486 1.2e-36 yhjE S protein conserved in bacteria
KKNCFHKG_02487 1.5e-49 P Rhodanese domain protein
KKNCFHKG_02488 1.5e-239 P Voltage gated chloride channel
KKNCFHKG_02491 6e-174 nodB1 G deacetylase
KKNCFHKG_02492 4.1e-12 recN L Putative cell-wall binding lipoprotein
KKNCFHKG_02493 4.7e-94 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
KKNCFHKG_02494 1.4e-90 ydhK M Protein of unknown function (DUF1541)
KKNCFHKG_02495 1.5e-126 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_02496 3.8e-249 T PhoQ Sensor
KKNCFHKG_02498 9.1e-33 S Protein of unknown function (DUF2933)
KKNCFHKG_02501 9.5e-267 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKNCFHKG_02502 1.3e-27 yhjC S Protein of unknown function (DUF3311)
KKNCFHKG_02503 7.2e-225 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KKNCFHKG_02504 9.5e-71 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KKNCFHKG_02505 4.3e-68 lrpC K Transcriptional regulator
KKNCFHKG_02506 8.4e-57 S protein conserved in bacteria
KKNCFHKG_02507 2.4e-30 P Copper resistance protein CopZ
KKNCFHKG_02508 0.0 copA 3.6.3.54 P P-type ATPase
KKNCFHKG_02509 1.7e-58 EGP Major facilitator Superfamily
KKNCFHKG_02510 1.5e-165 S Protein of unknown function (DUF1646)
KKNCFHKG_02511 9.3e-116 sapB S MgtC SapB transporter
KKNCFHKG_02512 2.9e-149 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KKNCFHKG_02513 1e-21
KKNCFHKG_02518 1.7e-07
KKNCFHKG_02520 1.7e-07
KKNCFHKG_02521 1.5e-07
KKNCFHKG_02525 4.3e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KKNCFHKG_02527 2.1e-97 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KKNCFHKG_02528 1.9e-115 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KKNCFHKG_02529 4.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KKNCFHKG_02530 3.4e-217 ybbR S protein conserved in bacteria
KKNCFHKG_02531 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKNCFHKG_02532 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KKNCFHKG_02533 6.4e-70 K helix_turn_helix, Arsenical Resistance Operon Repressor
KKNCFHKG_02534 3.6e-48 ykvR S Protein of unknown function (DUF3219)
KKNCFHKG_02535 2.4e-173 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKNCFHKG_02537 3.1e-237 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
KKNCFHKG_02538 9e-220 mvaS 2.3.3.10 I synthase
KKNCFHKG_02539 2.6e-211 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KKNCFHKG_02540 5e-54 S DsrE/DsrF-like family
KKNCFHKG_02541 5.6e-74
KKNCFHKG_02542 5.3e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKNCFHKG_02543 4.2e-110 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KKNCFHKG_02544 1.5e-151 L Transposase domain (DUF772)
KKNCFHKG_02545 1.2e-85 qorB 1.6.5.2 GM NmrA-like family
KKNCFHKG_02546 1.6e-126 L Transposase
KKNCFHKG_02547 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KKNCFHKG_02548 2e-169 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKNCFHKG_02551 1e-12 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
KKNCFHKG_02552 5.5e-40 yhjA S Excalibur calcium-binding domain
KKNCFHKG_02553 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KKNCFHKG_02554 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KKNCFHKG_02555 6.2e-99 cotE S Outer spore coat protein E (CotE)
KKNCFHKG_02556 2.1e-49 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KKNCFHKG_02557 5.2e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KKNCFHKG_02558 3.6e-260 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKNCFHKG_02559 1.5e-288 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KKNCFHKG_02561 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KKNCFHKG_02562 9.4e-245 E Amino acid permease
KKNCFHKG_02563 2.9e-248 yegQ O COG0826 Collagenase and related proteases
KKNCFHKG_02564 1.1e-167 yegQ O Peptidase U32
KKNCFHKG_02565 3.3e-37 spoVS S Stage V sporulation protein S
KKNCFHKG_02566 7.2e-152 ymdB S protein conserved in bacteria
KKNCFHKG_02567 5.6e-217 rny S Endoribonuclease that initiates mRNA decay
KKNCFHKG_02568 1.9e-106 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KKNCFHKG_02569 9.6e-167 yocS S -transporter
KKNCFHKG_02570 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KKNCFHKG_02571 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KKNCFHKG_02572 1.3e-151 yicC S stress-induced protein
KKNCFHKG_02573 3.8e-45 ylzA S Belongs to the UPF0296 family
KKNCFHKG_02574 3.7e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KKNCFHKG_02575 7.6e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KKNCFHKG_02576 3.2e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KKNCFHKG_02577 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKNCFHKG_02578 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KKNCFHKG_02579 1.7e-179 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KKNCFHKG_02580 1.7e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KKNCFHKG_02581 1.2e-135 stp 3.1.3.16 T phosphatase
KKNCFHKG_02582 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KKNCFHKG_02583 1.8e-167 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KKNCFHKG_02584 6.8e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KKNCFHKG_02585 1.5e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
KKNCFHKG_02586 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KKNCFHKG_02588 9.9e-101 ycnI S Domain of unkown function (DUF1775)
KKNCFHKG_02589 4.7e-291 ycnJ P protein, homolog of Cu resistance protein CopC
KKNCFHKG_02590 3.5e-26
KKNCFHKG_02592 4.7e-263 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KKNCFHKG_02593 6.6e-226 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
KKNCFHKG_02594 4.6e-31 cspL K Cold shock
KKNCFHKG_02595 1.9e-178 ydcZ S Putative inner membrane exporter, YdcZ
KKNCFHKG_02596 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KKNCFHKG_02597 6.6e-309 ampC V Belongs to the UPF0214 family
KKNCFHKG_02598 4.1e-234 ybbC 3.2.1.52 S protein conserved in bacteria
KKNCFHKG_02599 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKNCFHKG_02600 0.0 yfiB V ABC transporter
KKNCFHKG_02601 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
KKNCFHKG_02602 5.7e-51 L Transposase
KKNCFHKG_02603 3.4e-173 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KKNCFHKG_02604 4.9e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KKNCFHKG_02605 2.8e-207 U protein localization to endoplasmic reticulum
KKNCFHKG_02606 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KKNCFHKG_02607 9.4e-91 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
KKNCFHKG_02608 7.8e-99 mleR K LysR substrate binding domain
KKNCFHKG_02609 1.5e-157 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
KKNCFHKG_02610 7.9e-25 mleP S Membrane transport protein
KKNCFHKG_02612 7.7e-132 K Helix-turn-helix domain, rpiR family
KKNCFHKG_02613 1.9e-292 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKNCFHKG_02614 2.7e-260 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KKNCFHKG_02615 4.5e-80 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KKNCFHKG_02616 1.9e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KKNCFHKG_02617 9.7e-115 E LysE type translocator
KKNCFHKG_02618 5.7e-26
KKNCFHKG_02619 1.8e-237 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KKNCFHKG_02620 4.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KKNCFHKG_02621 3.2e-162 ybaS 1.1.1.58 S Na -dependent transporter
KKNCFHKG_02623 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KKNCFHKG_02624 3e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
KKNCFHKG_02627 7.2e-275 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
KKNCFHKG_02628 5.2e-307 yhcA5 EGP Major facilitator Superfamily
KKNCFHKG_02629 2.2e-106 emrA V COG1566 Multidrug resistance efflux pump
KKNCFHKG_02630 1.3e-67 K helix_turn_helix multiple antibiotic resistance protein
KKNCFHKG_02631 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KKNCFHKG_02632 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKNCFHKG_02633 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KKNCFHKG_02634 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KKNCFHKG_02635 1.1e-175 phnD P Phosphonate ABC transporter
KKNCFHKG_02636 6.1e-143 phnE 3.6.1.63 P ABC transporter
KKNCFHKG_02637 2.3e-134 phnE 3.6.1.63 P ABC transporter
KKNCFHKG_02638 1.2e-135 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KKNCFHKG_02639 3.8e-195 S Metallo-beta-lactamase superfamily
KKNCFHKG_02640 9.5e-26 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KKNCFHKG_02641 6.2e-265 Otg1 S Predicted membrane protein (DUF2339)
KKNCFHKG_02642 6.9e-59 xylS 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KKNCFHKG_02643 4.3e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KKNCFHKG_02644 6.8e-93 S UPF0397 protein
KKNCFHKG_02645 0.0 ykoD P ABC transporter, ATP-binding protein
KKNCFHKG_02646 4.3e-150 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
KKNCFHKG_02647 1e-142 focA P Formate nitrite
KKNCFHKG_02648 1e-88 S NYN domain
KKNCFHKG_02649 3.4e-76 L PFAM Integrase, catalytic core
KKNCFHKG_02650 1.6e-86 mntP P Probably functions as a manganese efflux pump
KKNCFHKG_02651 1.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KKNCFHKG_02652 5.4e-133 spoIIR S Stage II sporulation protein R (spore_II_R)
KKNCFHKG_02653 4.1e-161 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KKNCFHKG_02654 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KKNCFHKG_02656 1.3e-110 tdk 2.7.1.21 F thymidine kinase
KKNCFHKG_02657 2.2e-33 rpmE J Ribosomal protein L31
KKNCFHKG_02658 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KKNCFHKG_02660 2.7e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KKNCFHKG_02661 8.1e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKNCFHKG_02662 4.4e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KKNCFHKG_02663 2.1e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KKNCFHKG_02664 6e-61 spo0F T response regulator
KKNCFHKG_02665 2.5e-198
KKNCFHKG_02666 2.5e-48
KKNCFHKG_02667 1.8e-102 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KKNCFHKG_02668 2.1e-55 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KKNCFHKG_02669 1.1e-189 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KKNCFHKG_02670 7.8e-216 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKNCFHKG_02671 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KKNCFHKG_02672 6.1e-55 ndoA L Toxic component of a toxin-antitoxin (TA) module
KKNCFHKG_02673 2.2e-151 rsbR T Positive regulator of sigma-B
KKNCFHKG_02674 8.1e-55 rsbS T antagonist
KKNCFHKG_02675 4.5e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KKNCFHKG_02676 8.1e-185 rsbU 3.1.3.3 KT phosphatase
KKNCFHKG_02677 4e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
KKNCFHKG_02678 6.7e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KKNCFHKG_02679 8.6e-134 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKNCFHKG_02680 5.2e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KKNCFHKG_02681 0.0 yhgF K COG2183 Transcriptional accessory protein
KKNCFHKG_02682 3e-92 ydcK S Belongs to the SprT family
KKNCFHKG_02690 1.6e-08
KKNCFHKG_02695 1.5e-155 galM 5.1.3.3 G Aldose 1-epimerase
KKNCFHKG_02697 4.1e-51
KKNCFHKG_02699 9.5e-16 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KKNCFHKG_02700 3.3e-161 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
KKNCFHKG_02701 5e-128 V COG1131 ABC-type multidrug transport system, ATPase component
KKNCFHKG_02703 5e-197 ybhR V COG0842 ABC-type multidrug transport system, permease component
KKNCFHKG_02704 3.5e-112 K Transcriptional regulator
KKNCFHKG_02705 3.7e-271 lysP E amino acid
KKNCFHKG_02706 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
KKNCFHKG_02707 2.1e-266 hsdM 2.1.1.72 V Type I restriction-modification system
KKNCFHKG_02708 4.4e-38 3.1.21.3 V Type I restriction modification DNA specificity domain
KKNCFHKG_02709 4.3e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KKNCFHKG_02710 6.2e-207 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KKNCFHKG_02711 1.7e-179 mocA S Oxidoreductase
KKNCFHKG_02712 3.4e-74 dps P Ferritin-like domain
KKNCFHKG_02713 2.7e-124 S membrane transporter protein
KKNCFHKG_02714 1.3e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KKNCFHKG_02715 3.9e-75 nsrR K Transcriptional regulator
KKNCFHKG_02716 3.8e-142 tesE Q COG3971 2-keto-4-pentenoate hydratase
KKNCFHKG_02717 1.5e-245 proP EGP Transporter
KKNCFHKG_02718 1.7e-179 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KKNCFHKG_02720 4.9e-145 L Transposase DDE domain
KKNCFHKG_02721 3.6e-205 nifS 2.8.1.7 E Cysteine desulfurase
KKNCFHKG_02722 2.8e-304 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KKNCFHKG_02723 3.2e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KKNCFHKG_02724 6.1e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KKNCFHKG_02725 8.7e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KKNCFHKG_02726 4.6e-21
KKNCFHKG_02727 7.6e-148 S transposase or invertase
KKNCFHKG_02728 2.8e-301 comM O Mg chelatase subunit ChlI
KKNCFHKG_02729 1.6e-51 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KKNCFHKG_02730 5.9e-137 yflN_1 S Metallo-beta-lactamase superfamily
KKNCFHKG_02731 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KKNCFHKG_02732 4.6e-227 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KKNCFHKG_02733 7.4e-132 treR K transcriptional
KKNCFHKG_02734 4.2e-65 EG COG2610 H gluconate symporter and related permeases
KKNCFHKG_02735 3.1e-308 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KKNCFHKG_02736 8.5e-125 gntR K transcriptional
KKNCFHKG_02737 3.6e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KKNCFHKG_02738 5e-81 fld C Flavodoxin
KKNCFHKG_02739 6.9e-198 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KKNCFHKG_02740 2.4e-152 T PhoQ Sensor
KKNCFHKG_02741 2.2e-99 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKNCFHKG_02742 2.9e-77 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KKNCFHKG_02743 1.5e-108 natA V COG1131 ABC-type multidrug transport system, ATPase component
KKNCFHKG_02744 0.0 M Peptidase M30
KKNCFHKG_02745 3.2e-59 croE S Helix-turn-helix
KKNCFHKG_02746 3.5e-135 E IrrE N-terminal-like domain
KKNCFHKG_02747 1.9e-38
KKNCFHKG_02748 4.2e-245 yicJ G MFS/sugar transport protein
KKNCFHKG_02749 1.5e-302 2.7.1.12, 2.7.1.17 G xylulose kinase
KKNCFHKG_02751 5e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KKNCFHKG_02752 6.7e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KKNCFHKG_02753 2.1e-88 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KKNCFHKG_02754 2.5e-120 yaaH M Glycoside Hydrolase Family
KKNCFHKG_02755 3.8e-37 yaaH M Glycoside Hydrolase Family
KKNCFHKG_02756 1.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KKNCFHKG_02757 3.3e-126 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KKNCFHKG_02758 6.5e-09
KKNCFHKG_02759 3.4e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KKNCFHKG_02760 1.3e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KKNCFHKG_02761 6.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KKNCFHKG_02762 1e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KKNCFHKG_02763 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KKNCFHKG_02764 3.6e-179 yaaC S YaaC-like Protein
KKNCFHKG_02765 2.8e-26 S Protein of unknown function (DUF3006)
KKNCFHKG_02766 1.1e-242 L Metallo-beta-lactamase superfamily
KKNCFHKG_02767 4.2e-65 S Protein of unknown function (DUF1648)
KKNCFHKG_02768 6.4e-68 yjbR S YjbR
KKNCFHKG_02769 4.2e-178 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KKNCFHKG_02770 2.4e-284 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
KKNCFHKG_02771 5e-204 S Protein of unknown function (DUF917)
KKNCFHKG_02772 1.9e-205 codB F cytosine purines uracil thiamine allantoin
KKNCFHKG_02773 8.7e-279 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
KKNCFHKG_02774 5.8e-200 S Protein of unknown function (DUF917)
KKNCFHKG_02775 8e-211 ynfM EGP Major facilitator Superfamily
KKNCFHKG_02776 0.0 ywjA V ABC transporter
KKNCFHKG_02778 4.3e-234 pbuG S permease
KKNCFHKG_02779 3.3e-155 glcT K antiterminator
KKNCFHKG_02780 0.0 2.7.1.201, 2.7.1.211 G phosphotransferase system
KKNCFHKG_02781 9.3e-223 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKNCFHKG_02783 1.5e-11 ymbI L Transposase
KKNCFHKG_02784 2.2e-84 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KKNCFHKG_02785 5.9e-170 K Transcriptional regulator
KKNCFHKG_02786 8.7e-210 EGP Major facilitator Superfamily
KKNCFHKG_02787 4.2e-74 K transcriptional
KKNCFHKG_02788 1e-193 ydjE EGP Major facilitator superfamily
KKNCFHKG_02789 3.1e-74 G Glycosyl hydrolases family 39
KKNCFHKG_02790 2.3e-115 K helix_turn_helix, arabinose operon control protein
KKNCFHKG_02791 6.1e-255 gph G MFS/sugar transport protein
KKNCFHKG_02792 1e-17 K Acetyltransferase (GNAT) family
KKNCFHKG_02793 7.7e-52 L IstB-like ATP binding protein
KKNCFHKG_02795 2e-22 EGP Transmembrane secretion effector
KKNCFHKG_02798 3.5e-168 L Transposase DDE domain
KKNCFHKG_02799 1.1e-62 cadC K transcriptional
KKNCFHKG_02800 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KKNCFHKG_02801 5.9e-77
KKNCFHKG_02802 6.5e-125 yhcG V ABC transporter, ATP-binding protein
KKNCFHKG_02803 2e-65 K helix_turn_helix gluconate operon transcriptional repressor
KKNCFHKG_02804 1.1e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KKNCFHKG_02805 2.1e-36 L Archaeal putative transposase ISC1217
KKNCFHKG_02806 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KKNCFHKG_02807 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KKNCFHKG_02808 4.8e-108
KKNCFHKG_02809 3e-120 mta K transcriptional
KKNCFHKG_02810 5.6e-118 L Transposase
KKNCFHKG_02811 4.1e-96 L Bacterial dnaA protein
KKNCFHKG_02813 0.0 2.1.1.80, 3.1.1.61, 3.4.21.105 L DNA recombination
KKNCFHKG_02821 1.7e-07
KKNCFHKG_02822 8.7e-08
KKNCFHKG_02826 1.6e-08
KKNCFHKG_02830 2.2e-199 adhC 1.1.1.1 C Zinc-binding dehydrogenase
KKNCFHKG_02831 3.8e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKNCFHKG_02833 1.9e-71 L COG2801 Transposase and inactivated derivatives
KKNCFHKG_02834 6.7e-120 msmE7 G Bacterial extracellular solute-binding protein
KKNCFHKG_02835 6.2e-122 msmF3 U Binding-protein-dependent transport system inner membrane component
KKNCFHKG_02836 2.9e-119 U Binding-protein-dependent transport system inner membrane component
KKNCFHKG_02837 5.4e-255 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KKNCFHKG_02838 6.6e-306 ywqB S Zinc finger, swim domain protein
KKNCFHKG_02839 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KKNCFHKG_02840 1.1e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_02841 2.4e-53 yodB K transcriptional
KKNCFHKG_02842 6.7e-193 S Protein of unknown function (DUF1648)
KKNCFHKG_02843 1.5e-68 K helix_turn_helix gluconate operon transcriptional repressor
KKNCFHKG_02844 7.7e-81 ywrA P COG2059 Chromate transport protein ChrA
KKNCFHKG_02845 8.7e-86 chrA P Chromate transporter
KKNCFHKG_02846 2.8e-50
KKNCFHKG_02848 2.8e-174 K cell envelope-related transcriptional attenuator
KKNCFHKG_02849 2e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKNCFHKG_02850 9.2e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KKNCFHKG_02851 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KKNCFHKG_02852 3.4e-08 yaaL S Protein of unknown function (DUF2508)
KKNCFHKG_02853 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KKNCFHKG_02854 7.3e-151 msrR K COG1316 Transcriptional regulator
KKNCFHKG_02855 1.2e-98 yngC S membrane-associated protein
KKNCFHKG_02856 1.7e-227 S SNARE associated Golgi protein
KKNCFHKG_02857 1.4e-35 3.2.1.78 GH26 O cellulase activity
KKNCFHKG_02858 0.0 ybeC E amino acid
KKNCFHKG_02859 1e-57 ulaG S L-ascorbate 6-phosphate lactonase
KKNCFHKG_02861 3.1e-69 dgoT G COG0477 Permeases of the major facilitator superfamily
KKNCFHKG_02862 6.1e-137 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KKNCFHKG_02864 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KKNCFHKG_02865 1.3e-29 P Heavy-metal-associated domain
KKNCFHKG_02866 1.2e-51 L Transposase, IS4 family protein
KKNCFHKG_02867 7.9e-295 S Immune inhibitor A peptidase M6
KKNCFHKG_02869 1.1e-19 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKNCFHKG_02870 9.9e-125 mmr U Major Facilitator Superfamily
KKNCFHKG_02871 1.1e-37 K HxlR-like helix-turn-helix
KKNCFHKG_02872 1e-151 yetF1 S membrane
KKNCFHKG_02873 3.8e-28 S Protein of unknown function (DUF1657)
KKNCFHKG_02874 7.4e-194 spoVAD I Stage V sporulation protein AD
KKNCFHKG_02875 5.1e-25 S Protein of unknown function (DUF1657)
KKNCFHKG_02876 4.2e-16 L Transposase, IS4 family protein
KKNCFHKG_02877 3.8e-145 pdaC 3.5.1.104 G Polysaccharide deacetylase
KKNCFHKG_02880 5.6e-42
KKNCFHKG_02881 2.6e-129 V ABC transporter
KKNCFHKG_02882 2.5e-33 C acyl-CoA transferases carnitine dehydratase
KKNCFHKG_02883 6.5e-182 yfmJ S N-terminal domain of oxidoreductase
KKNCFHKG_02884 2.5e-15 S Ribbon-helix-helix protein, copG family
KKNCFHKG_02885 1.2e-210 L COG4584 Transposase and inactivated derivatives
KKNCFHKG_02886 1.9e-111 L Bacterial dnaA protein
KKNCFHKG_02887 1.5e-230 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KKNCFHKG_02888 2.4e-131 U AAA domain
KKNCFHKG_02889 3.2e-155 L Mu transposase, C-terminal
KKNCFHKG_02890 3.4e-214 EGP Major facilitator Superfamily
KKNCFHKG_02891 5.1e-44 2.7.1.202 K transcriptional regulator, MtlR
KKNCFHKG_02892 1.8e-41 S transposase or invertase
KKNCFHKG_02893 1.9e-172 ydhF S Oxidoreductase
KKNCFHKG_02895 1.7e-69 L COG2801 Transposase and inactivated derivatives
KKNCFHKG_02896 2.6e-69 L COG2801 Transposase and inactivated derivatives
KKNCFHKG_02897 3.3e-46 L COG2963 Transposase and inactivated derivatives
KKNCFHKG_02900 2.2e-75 5.4.2.11 G Phosphoglycerate mutase family
KKNCFHKG_02901 4.3e-18 L Helix-turn-helix domain of resolvase
KKNCFHKG_02902 2.8e-132 IQ Enoyl-(Acyl carrier protein) reductase
KKNCFHKG_02903 4.4e-16 L Transposase, IS4 family protein
KKNCFHKG_02904 8.4e-45 L Mu transposase, C-terminal
KKNCFHKG_02905 5.3e-71 L Transposase, IS4 family protein
KKNCFHKG_02906 3.3e-120 L Transposase
KKNCFHKG_02907 6.3e-73 L resolvase
KKNCFHKG_02908 8.2e-64 L Transposase IS200 like
KKNCFHKG_02909 8e-42 L Transposase
KKNCFHKG_02910 6.9e-64 L COG2801 Transposase and inactivated derivatives
KKNCFHKG_02914 4e-08
KKNCFHKG_02915 1.6e-08
KKNCFHKG_02916 1.6e-37
KKNCFHKG_02919 1.9e-15 S Ribbon-helix-helix protein, copG family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)