ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHMNNKED_00001 8.1e-31 acyP 3.6.1.7 C Acylphosphatase
MHMNNKED_00003 1.9e-169 narK P COG2223 Nitrate nitrite transporter
MHMNNKED_00004 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHMNNKED_00005 1.6e-285 narH 1.7.5.1 C Nitrate reductase, beta
MHMNNKED_00006 1.8e-45 narJ 1.7.5.1 C nitrate reductase
MHMNNKED_00007 9.7e-97 narI 1.7.5.1 C nitrate reductase, gamma subunit
MHMNNKED_00008 2.6e-139 S Tetratricopeptide repeats
MHMNNKED_00009 6.2e-32
MHMNNKED_00010 1.4e-65 ytaF P Probably functions as a manganese efflux pump
MHMNNKED_00011 4.3e-123 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHMNNKED_00012 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHMNNKED_00013 1.4e-114 hflC O HflC and HflK could regulate a protease
MHMNNKED_00014 1.8e-96 hflK O HflC and HflK could encode or regulate a protease
MHMNNKED_00015 3.7e-193 phoR 2.7.13.3 T Signal transduction histidine kinase
MHMNNKED_00016 5.3e-106 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_00017 6.3e-147 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MHMNNKED_00018 9.1e-226 icd 1.1.1.42 C isocitrate
MHMNNKED_00019 5.3e-177 citZ 2.3.3.1 C Belongs to the citrate synthase family
MHMNNKED_00020 6.7e-108 ytvI S sporulation integral membrane protein YtvI
MHMNNKED_00021 1.7e-34 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHMNNKED_00022 2e-279 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MHMNNKED_00023 3.7e-147 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHMNNKED_00024 1.4e-144 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHMNNKED_00025 9.5e-126 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHMNNKED_00026 2.9e-47 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
MHMNNKED_00027 7.4e-172 ytsJ 1.1.1.38 C Malate dehydrogenase
MHMNNKED_00028 0.0 dnaE 2.7.7.7 L DNA polymerase
MHMNNKED_00029 2e-47 ytrH S Sporulation protein YtrH
MHMNNKED_00030 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MHMNNKED_00031 6.2e-126 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHMNNKED_00032 4.1e-199 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHMNNKED_00033 5.8e-218 argH 4.3.2.1 E argininosuccinate lyase
MHMNNKED_00034 5.8e-15 yckD S Protein of unknown function (DUF2680)
MHMNNKED_00035 1.3e-29 yhdT S Sodium pantothenate symporter
MHMNNKED_00036 9.1e-206 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHMNNKED_00037 7e-138 murB 1.3.1.98 M cell wall formation
MHMNNKED_00038 1.4e-123 ydbI S AI-2E family transporter
MHMNNKED_00039 5.1e-162 xylR GK ROK family
MHMNNKED_00041 1.9e-10
MHMNNKED_00042 1.8e-111 sodA 1.15.1.1 P Superoxide dismutase
MHMNNKED_00043 4.2e-13 S Carbon monoxide dehydrogenase subunit G (CoxG)
MHMNNKED_00044 1.1e-32 yrkD S protein conserved in bacteria
MHMNNKED_00045 7e-36 P Rhodanese Homology Domain
MHMNNKED_00046 1.2e-260 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHMNNKED_00047 3.5e-37 P Rhodanese Homology Domain
MHMNNKED_00048 7.7e-12 O Glutaredoxin
MHMNNKED_00049 6.8e-126 pgl 3.1.1.31 G 6-phosphogluconolactonase
MHMNNKED_00051 2.6e-165 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
MHMNNKED_00052 5.2e-131 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MHMNNKED_00053 1.2e-124 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MHMNNKED_00054 1.4e-133 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHMNNKED_00055 4.6e-145 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHMNNKED_00056 7.9e-127 ycsI S Belongs to the D-glutamate cyclase family
MHMNNKED_00057 8.4e-173 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHMNNKED_00058 2.9e-118 ycsF S Belongs to the UPF0271 (lamB) family
MHMNNKED_00059 2.2e-121 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MHMNNKED_00060 9.4e-95 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MHMNNKED_00061 4.5e-242 sbcC L COG0419 ATPase involved in DNA repair
MHMNNKED_00062 2.3e-178 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHMNNKED_00063 1.7e-29 S Domain of unknown function (DUF4652)
MHMNNKED_00064 3.6e-232 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MHMNNKED_00065 8.2e-98 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MHMNNKED_00066 5e-140 capA M Bacterial capsule synthesis protein PGA_cap
MHMNNKED_00067 4.3e-146 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHMNNKED_00068 6.8e-112 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MHMNNKED_00069 3.5e-139 ydaH H AbgT putative transporter family
MHMNNKED_00070 5.4e-63 L Replication initiation and membrane attachment
MHMNNKED_00071 3.3e-56 D peptidase
MHMNNKED_00072 1e-114 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHMNNKED_00073 3.5e-107 ftsE D cell division ATP-binding protein FtsE
MHMNNKED_00074 5.3e-203 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHMNNKED_00075 1.8e-29 sugE P Multidrug resistance protein
MHMNNKED_00076 1.1e-35 ykkC P Multidrug resistance protein
MHMNNKED_00077 7e-120 yumC 1.18.1.2, 1.19.1.1 C reductase
MHMNNKED_00078 1.7e-16 fdxA C 4Fe-4S binding domain
MHMNNKED_00079 5.3e-176 paaK 6.2.1.30 H AMP-binding enzyme
MHMNNKED_00080 1e-152 paaA 1.14.13.149 S With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA
MHMNNKED_00081 2.1e-30 paaB Q Phenylacetate-CoA oxygenase subunit PaaH
MHMNNKED_00082 6.1e-87 paaC 1.14.13.149 Q Phenylacetate-CoA oxygenase
MHMNNKED_00083 9.7e-54 paaD S Phenylacetate-CoA oxygenase
MHMNNKED_00084 2.3e-42 ethD S Ethyl tert-butyl ether degradation
MHMNNKED_00085 9.3e-96 paaF 4.2.1.17 I Enoyl-CoA hydratase/isomerase
MHMNNKED_00086 1.1e-88 paaG 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MHMNNKED_00087 2e-99 paaX K PaaX-like protein
MHMNNKED_00088 3.9e-104 1.3.1.9 S Dihydroorotate dehydrogenase
MHMNNKED_00089 4.6e-49 Q Thioesterase superfamily
MHMNNKED_00090 4.2e-51 K helix_turn_helix ASNC type
MHMNNKED_00091 5.2e-123 ybbF 2.7.1.211 G phosphotransferase system
MHMNNKED_00092 1.9e-123 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MHMNNKED_00093 5.2e-205 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHMNNKED_00094 1.8e-76 yczE S membrane
MHMNNKED_00095 2.5e-58 cymR K Transcriptional regulator
MHMNNKED_00096 4.3e-158 iscS 2.8.1.7 E Cysteine desulfurase
MHMNNKED_00097 9.9e-192 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHMNNKED_00098 4e-34 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHMNNKED_00099 2.3e-49 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHMNNKED_00100 1e-133 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHMNNKED_00101 7.3e-94 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHMNNKED_00102 1.5e-46 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHMNNKED_00103 2.1e-166 G Bacterial extracellular solute-binding protein
MHMNNKED_00104 8.6e-157 sugA G Binding-protein-dependent transport system inner membrane component
MHMNNKED_00105 5.4e-110 G Binding-protein-dependent transport system inner membrane component
MHMNNKED_00106 2.5e-282 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
MHMNNKED_00107 8.4e-80 sfsA S Belongs to the SfsA family
MHMNNKED_00108 1.7e-16 S Family of unknown function (DUF5327)
MHMNNKED_00109 2.1e-37 ywdK S small membrane protein
MHMNNKED_00110 3.4e-56 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHMNNKED_00111 1.3e-67 cwlJ 3.5.1.28 M Cell wall
MHMNNKED_00112 1.1e-100 bshB2 S deacetylase
MHMNNKED_00113 5.8e-33 yesJ 3.1.3.48 K Acetyltransferase (GNAT) family
MHMNNKED_00114 1e-245 aidB I Acyl-CoA dehydrogenase, middle domain
MHMNNKED_00115 6.7e-195 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_00116 1.6e-10 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_00117 1e-45 cueR K transcriptional
MHMNNKED_00118 1e-225 L COG3316 Transposase and inactivated derivatives
MHMNNKED_00119 2.5e-129 yqhO S esterase of the alpha-beta hydrolase superfamily
MHMNNKED_00120 2.2e-07 yqhP
MHMNNKED_00121 7.6e-54 yqhR S Conserved membrane protein YqhR
MHMNNKED_00122 1.2e-143 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHMNNKED_00123 1.2e-89 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHMNNKED_00124 8.4e-128 spoIIIAA S stage III sporulation protein AA
MHMNNKED_00125 2.9e-61 spoIIIAB S Stage III sporulation protein
MHMNNKED_00126 1.3e-25 spoIIIAC S stage III sporulation protein AC
MHMNNKED_00127 7.6e-28 spoIIIAD S Stage III sporulation protein AD
MHMNNKED_00128 1.9e-148 spoIIIAE S stage III sporulation protein AE
MHMNNKED_00129 5.9e-22 fsr P COG0477 Permeases of the major facilitator superfamily
MHMNNKED_00130 5.6e-69
MHMNNKED_00131 3.2e-23 ynzC S Bacterial protein of unknown function (DUF896)
MHMNNKED_00132 2.4e-29
MHMNNKED_00133 2.7e-72 S Carboxylesterase
MHMNNKED_00134 1.7e-44 S CBS domain
MHMNNKED_00135 1.5e-23 yuzC
MHMNNKED_00136 1.8e-41 K Transcriptional regulator PadR-like family
MHMNNKED_00137 5.4e-96 1.3.1.84, 4.2.1.116, 6.2.1.36 C alcohol dehydrogenase
MHMNNKED_00138 4.4e-77 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MHMNNKED_00139 8.4e-154 sat 2.7.7.4 P PUA-like domain
MHMNNKED_00140 2.8e-203 yfiU EGP Fungal trichothecene efflux pump (TRI12)
MHMNNKED_00141 5.9e-204 proP EGP Transporter
MHMNNKED_00142 2e-155 S Domain of unknown function (DUF4317)
MHMNNKED_00143 1.5e-54 bar 2.3.1.183 M Acetyltransferase (GNAT) domain
MHMNNKED_00144 1.2e-15
MHMNNKED_00145 3e-72 yhcI S ABC-2 family transporter protein
MHMNNKED_00146 1.7e-104 yhcH V ABC transporter, ATP-binding protein
MHMNNKED_00147 2.4e-85 yhcG V ABC transporter, ATP-binding protein
MHMNNKED_00148 4.5e-40 yhcF K Transcriptional regulator
MHMNNKED_00149 3.2e-24
MHMNNKED_00150 1.3e-151 sufD O assembly protein SufD
MHMNNKED_00151 3.2e-191 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHMNNKED_00152 1.4e-51 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MHMNNKED_00153 3.6e-239 sufB O FeS cluster assembly
MHMNNKED_00154 3.6e-154 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHMNNKED_00155 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHMNNKED_00156 8.2e-114 yunF S Protein of unknown function DUF72
MHMNNKED_00157 1.4e-182 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MHMNNKED_00158 1.2e-35 yunC S Domain of unknown function (DUF1805)
MHMNNKED_00159 7.9e-42 ssuE 1.5.1.38 S NADPH-dependent FMN reductase
MHMNNKED_00160 3.6e-54 ssuE 1.5.1.38 S NADPH-dependent FMN reductase
MHMNNKED_00161 5e-153 msuD 1.14.14.35 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHMNNKED_00162 4.4e-07
MHMNNKED_00163 3e-245 dppE_1 E ABC transporter substrate-binding protein
MHMNNKED_00164 2e-163 acuC BQ histone deacetylase
MHMNNKED_00165 2e-59 acuB S Acetoin utilization protein AcuB
MHMNNKED_00166 5.2e-97 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHMNNKED_00167 9.9e-21 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
MHMNNKED_00168 3e-96
MHMNNKED_00169 0.0 L SNF2 family N-terminal domain
MHMNNKED_00171 2.4e-57
MHMNNKED_00172 4e-184 hom 1.1.1.3 E homoserine dehydrogenase
MHMNNKED_00173 2.5e-81 tcaA S response to antibiotic
MHMNNKED_00174 2.7e-40 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
MHMNNKED_00175 6.6e-54 tcaA S response to antibiotic
MHMNNKED_00176 3.6e-44
MHMNNKED_00177 1e-92 flhP N flagellar basal body
MHMNNKED_00178 3.1e-07 epuA S DNA-directed RNA polymerase subunit beta
MHMNNKED_00179 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHMNNKED_00180 1.8e-49 2.7.8.20 M COG COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHMNNKED_00181 1.2e-151 gntP S Na+-H+ antiporter family
MHMNNKED_00182 3.1e-56 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHMNNKED_00183 7.2e-101 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHMNNKED_00184 1.6e-177 iolF EGP Sugar (and other) transporter
MHMNNKED_00185 1.8e-42 rhaM 5.1.3.32 G L-rhamnose mutarotase
MHMNNKED_00186 1.2e-106 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MHMNNKED_00187 2e-180 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
MHMNNKED_00188 1.2e-181 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MHMNNKED_00189 7.8e-76 rhaR K helix_turn_helix, arabinose operon control protein
MHMNNKED_00190 5.2e-288 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MHMNNKED_00192 7.4e-125 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MHMNNKED_00193 2.1e-48 yqhL P COG0607 Rhodanese-related sulfurtransferase
MHMNNKED_00194 2.3e-252 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHMNNKED_00195 1.6e-207 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHMNNKED_00196 5.3e-145 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MHMNNKED_00197 6.4e-267 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHMNNKED_00198 4e-102 yqhG S Bacterial protein YqhG of unknown function
MHMNNKED_00199 2.4e-07 yqzE S YqzE-like protein
MHMNNKED_00200 2.4e-14
MHMNNKED_00201 1.1e-33 comGF U Putative Competence protein ComGF
MHMNNKED_00202 1e-17
MHMNNKED_00203 2.4e-35 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
MHMNNKED_00204 1.6e-27 comGC U Required for transformation and DNA binding
MHMNNKED_00205 5.7e-93 comGB NU COG1459 Type II secretory pathway, component PulF
MHMNNKED_00206 1.3e-46 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHMNNKED_00207 8.4e-17 S EpsG family
MHMNNKED_00208 3e-132 S Polysaccharide biosynthesis protein
MHMNNKED_00209 2.6e-36 alg8 2.4.1.33 GT2 M transferase activity, transferring glycosyl groups
MHMNNKED_00210 5.8e-95 sacB GT2,GT4 M Stealth protein CR4, conserved region 4
MHMNNKED_00211 2.7e-54 S Endonuclease/Exonuclease/phosphatase family
MHMNNKED_00212 4.1e-73
MHMNNKED_00213 3.3e-13
MHMNNKED_00214 2.7e-37 S Protein of unknown function (DUF2975)
MHMNNKED_00215 5.4e-302 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHMNNKED_00216 2.4e-124 camS S COG4851 Protein involved in sex pheromone biosynthesis
MHMNNKED_00217 3.9e-168 purD 6.3.4.13 F Belongs to the GARS family
MHMNNKED_00218 1e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHMNNKED_00219 1.2e-65 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHMNNKED_00220 2.2e-137 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHMNNKED_00221 1.8e-206 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHMNNKED_00222 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHMNNKED_00223 9.4e-92 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHMNNKED_00224 2e-23 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHMNNKED_00225 6.5e-151 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHMNNKED_00226 2.6e-64 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHMNNKED_00227 1.2e-185 ytcJ S amidohydrolase
MHMNNKED_00228 3.8e-25 sasP S spore protein
MHMNNKED_00229 4.7e-171 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHMNNKED_00230 4.3e-158 iscS2 2.8.1.7 E Cysteine desulfurase
MHMNNKED_00231 9.7e-130 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHMNNKED_00232 4.5e-64 yttP K Transcriptional regulator
MHMNNKED_00233 5.2e-65 ytsP 1.8.4.14 T GAF domain-containing protein
MHMNNKED_00234 3.9e-161 ytrP 2.7.7.65 T PhoQ Sensor
MHMNNKED_00235 5.9e-69 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHMNNKED_00236 6.3e-40 iscA S Heme biosynthesis protein HemY
MHMNNKED_00237 7.7e-85 rnhA 3.1.26.4 L Caulimovirus viroplasmin
MHMNNKED_00238 1.5e-77 motB N Flagellar motor protein
MHMNNKED_00239 7.1e-99 motA N flagellar motor
MHMNNKED_00241 8.3e-118 xth 3.1.11.2 L exodeoxyribonuclease III
MHMNNKED_00242 1.9e-41
MHMNNKED_00243 5.5e-258 ilvD 4.2.1.9 E Dehydratase family
MHMNNKED_00244 6.5e-107 yocS S -transporter
MHMNNKED_00245 2.3e-251 ilvB 2.2.1.6 E Acetolactate synthase
MHMNNKED_00246 3.6e-72 ilvN 2.2.1.6 E Acetolactate synthase
MHMNNKED_00247 5.6e-157 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHMNNKED_00248 1.7e-113 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHMNNKED_00249 1.1e-216 XK27_08635 S UPF0210 protein
MHMNNKED_00250 2.3e-25 gcvR 1.1.1.3, 1.1.1.399, 1.1.1.95 T Belongs to the UPF0237 family
MHMNNKED_00252 1.2e-141 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
MHMNNKED_00253 2.2e-167 msmK P Belongs to the ABC transporter superfamily
MHMNNKED_00254 8.5e-85 QT PucR C-terminal helix-turn-helix domain
MHMNNKED_00255 2e-66 K Transcriptional regulator
MHMNNKED_00256 3.7e-71 S Protein of unknown function (DUF3298)
MHMNNKED_00258 5.8e-41 bp26 S Protein of unknown function (DUF541)
MHMNNKED_00259 6.3e-19 gerPE S Spore germination protein GerPE
MHMNNKED_00260 6.2e-11 gerPD S Spore germination protein
MHMNNKED_00261 3.4e-32 gerPC S Spore germination protein
MHMNNKED_00262 5.2e-10 gerPB S cell differentiation
MHMNNKED_00263 7.9e-24 gerPA S Spore germination protein
MHMNNKED_00264 2.6e-89 P Protein of unknown function (DUF418)
MHMNNKED_00265 9.4e-108 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHMNNKED_00266 7.4e-16 yisL S UPF0344 protein
MHMNNKED_00267 1.6e-57 yisN S Protein of unknown function (DUF2777)
MHMNNKED_00268 1.8e-99 amyA 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MHMNNKED_00269 1.7e-42 yajQ S Belongs to the UPF0234 family
MHMNNKED_00271 2.6e-118 yitS S protein conserved in bacteria
MHMNNKED_00272 1.2e-60 K Transcriptional regulator
MHMNNKED_00273 8.5e-91 ykoC P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
MHMNNKED_00274 1.8e-218 ykoD 3.6.3.24 P ABC transporter
MHMNNKED_00275 5.7e-76 ykoE S ABC-type cobalt transport system, permease component
MHMNNKED_00276 5.8e-08 S Protein of unknown function (DUF3936)
MHMNNKED_00277 2.8e-123 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MHMNNKED_00279 7.7e-11
MHMNNKED_00280 3.7e-128 yqkD S X-Pro dipeptidyl-peptidase (S15 family)
MHMNNKED_00282 4.4e-26 S YolD-like protein
MHMNNKED_00283 2.7e-201 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHMNNKED_00284 4.6e-138 hisC 2.6.1.9 E Aminotransferase class I and II
MHMNNKED_00285 1.7e-85 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MHMNNKED_00286 1.6e-116 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHMNNKED_00287 3.2e-82 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHMNNKED_00288 4.9e-84 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHMNNKED_00289 1.2e-87 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MHMNNKED_00290 1.7e-166 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHMNNKED_00291 1.5e-78 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHMNNKED_00292 1.7e-118 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHMNNKED_00293 1.6e-56 MA20_02285 2.3.1.57 K PFAM Acetyltransferase (GNAT) family
MHMNNKED_00294 3.2e-272 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Polyprenyl synthetase
MHMNNKED_00295 3.7e-179 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHMNNKED_00296 1.3e-54 yjbF S SNARE associated Golgi protein
MHMNNKED_00297 1.7e-126 dgs 2.4.1.208 GT4 M Glycosyltransferase Family 4
MHMNNKED_00298 1.1e-42 mcpB_1 NT chemotaxis protein
MHMNNKED_00299 1.2e-102 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHMNNKED_00300 1.7e-08 S granule-associated protein
MHMNNKED_00301 3e-46 fld C Flavodoxin
MHMNNKED_00302 1.5e-16 S Bacterial-like globin
MHMNNKED_00303 7.1e-30
MHMNNKED_00304 2.8e-163 uhpT EGP Mycoplasma MFS transporter
MHMNNKED_00305 2.9e-08 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHMNNKED_00306 6.8e-67 K Acetyltransferase (GNAT) domain
MHMNNKED_00307 2.8e-100 IQ Short-chain dehydrogenase
MHMNNKED_00308 2.3e-08
MHMNNKED_00309 4.5e-69 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHMNNKED_00310 6e-46 S Protein of unknown function, DUF624
MHMNNKED_00311 7e-123 malR 5.1.1.1 K Transcriptional regulator
MHMNNKED_00312 2.4e-110 amyC P ABC-type sugar transport system, permease component
MHMNNKED_00313 3.9e-119 G Binding-protein-dependent transport system inner membrane component
MHMNNKED_00314 5.9e-172 G Bacterial extracellular solute-binding protein
MHMNNKED_00315 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MHMNNKED_00316 1.8e-98 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHMNNKED_00317 3.1e-40 yerC S protein conserved in bacteria
MHMNNKED_00318 1.1e-117 yerB S Protein of unknown function (DUF3048) C-terminal domain
MHMNNKED_00319 2.4e-76 yerA 3.5.4.2 F adenine deaminase
MHMNNKED_00320 8.6e-104 KLT serine threonine protein kinase
MHMNNKED_00321 8.3e-94 yabS S protein containing a von Willebrand factor type A (vWA) domain
MHMNNKED_00322 1.8e-281 spoIIE 3.1.3.16 KT stage II sporulation protein E
MHMNNKED_00323 9.1e-50 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MHMNNKED_00324 5.5e-15 divIC D Septum formation initiator
MHMNNKED_00325 2.7e-42 yabQ S spore cortex biosynthesis protein
MHMNNKED_00326 6.1e-43 yabP S Sporulation protein YabP
MHMNNKED_00327 2.2e-28 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHMNNKED_00328 1.6e-197 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHMNNKED_00329 4.8e-131 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHMNNKED_00330 2e-81 spoVT K stage V sporulation protein
MHMNNKED_00331 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHMNNKED_00332 2.5e-25 yabK S Peptide ABC transporter permease
MHMNNKED_00333 3.2e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHMNNKED_00334 2.4e-57 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHMNNKED_00335 1.1e-151 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHMNNKED_00336 1.7e-188 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHMNNKED_00337 6.9e-44 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHMNNKED_00338 2e-125 purR 2.4.2.7 F pur operon repressor
MHMNNKED_00339 1.1e-129 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHMNNKED_00340 8.7e-49 spoVAE S SpoVAC/SpoVAEB sporulation membrane protein
MHMNNKED_00341 1e-150 spoVAD I Stage V sporulation protein AD
MHMNNKED_00342 1.7e-71 spoVAC S stage V sporulation protein AC
MHMNNKED_00343 2.5e-32 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHMNNKED_00344 1.9e-77 ggaB M Glycosyltransferase like family 2
MHMNNKED_00345 1.8e-145 M Glycosyl transferases group 1
MHMNNKED_00346 4.1e-99 3.2.1.23 G Sulfotransferase family
MHMNNKED_00347 1.3e-133 M Glycosyltransferase Family 4
MHMNNKED_00348 3.1e-61 K Belongs to the GbsR family
MHMNNKED_00349 9.3e-172 opuAA 3.6.3.32 E Domain in cystathionine beta-synthase and other proteins.
MHMNNKED_00350 5.7e-115 opuAB E Binding-protein-dependent transport system inner membrane component
MHMNNKED_00351 3.6e-120 gbuC_2 E Substrate binding domain of ABC-type glycine betaine transport system
MHMNNKED_00352 1.6e-211 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_00354 5.2e-127 hcaT 1.5.1.2 EGP Major facilitator Superfamily
MHMNNKED_00355 1.7e-199 E Sodium:solute symporter family
MHMNNKED_00356 1.9e-58 ymdB S Appr-1'-p processing enzyme
MHMNNKED_00357 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHMNNKED_00358 2.6e-142 EGP Major facilitator Superfamily
MHMNNKED_00359 1e-16 S Iron-sulphur cluster biosynthesis
MHMNNKED_00360 1.7e-120 pldB 3.1.1.5 I Alpha beta hydrolase
MHMNNKED_00361 1.8e-144 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHMNNKED_00363 3.2e-202 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHMNNKED_00364 1.4e-170 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHMNNKED_00365 1e-136 spoVK O stage V sporulation protein K
MHMNNKED_00366 2.4e-28 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHMNNKED_00367 2.9e-128 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHMNNKED_00368 4.2e-197 tlyC S Transporter associated domain
MHMNNKED_00369 3.1e-35 T Universal stress protein family
MHMNNKED_00370 2.5e-234 ykoS
MHMNNKED_00371 1.9e-125 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHMNNKED_00372 3.8e-47 3.2.1.21 GH3 N Listeria-Bacteroides repeat domain (List_Bact_rpt)
MHMNNKED_00373 2.3e-19
MHMNNKED_00374 5.5e-104 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHMNNKED_00375 3.8e-57 spoVID M stage VI sporulation protein D
MHMNNKED_00376 2.8e-206 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHMNNKED_00377 5.9e-156 hemB 4.2.1.24 H Belongs to the ALAD family
MHMNNKED_00378 2.1e-71 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MHMNNKED_00379 2.7e-126 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHMNNKED_00380 1.6e-77 hemX O cytochrome C
MHMNNKED_00381 4.4e-178 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHMNNKED_00382 3.8e-47 ysxD
MHMNNKED_00383 2.1e-101 rfbD 1.1.1.133 M RmlD substrate binding domain
MHMNNKED_00384 5.9e-89 gca 1.1.1.281, 4.2.1.47, 5.1.3.2 GM GDP-mannose 4,6 dehydratase
MHMNNKED_00385 1.3e-74 M Glycosyltransferase like family 2
MHMNNKED_00386 1.5e-37 ypmS S protein conserved in bacteria
MHMNNKED_00387 3.2e-57 ypmR E COG2755 Lysophospholipase L1 and related esterases
MHMNNKED_00388 1.1e-67 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHMNNKED_00389 3.3e-91 degV S protein conserved in bacteria
MHMNNKED_00390 3.9e-82 yoqW S Belongs to the SOS response-associated peptidase family
MHMNNKED_00391 4.1e-65 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHMNNKED_00392 1.1e-139 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHMNNKED_00393 1.5e-65 3.4.24.89
MHMNNKED_00394 1.2e-53 ypjP S YpjP-like protein
MHMNNKED_00395 2.5e-58 yphP S Belongs to the UPF0403 family
MHMNNKED_00396 2.4e-113 ypgR C COG0694 Thioredoxin-like proteins and domains
MHMNNKED_00397 7.7e-253 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHMNNKED_00398 1.4e-60 ypgQ S phosphohydrolase
MHMNNKED_00399 1.9e-36
MHMNNKED_00400 3.9e-142 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHMNNKED_00401 1e-159 hemN H Involved in the biosynthesis of porphyrin-containing compound
MHMNNKED_00402 2.5e-309 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHMNNKED_00403 4.4e-09 NT chemotaxis protein
MHMNNKED_00404 4.7e-36 3.5.4.5 S ASCH
MHMNNKED_00405 2.9e-70 sleB 3.5.1.28 M Cell wall
MHMNNKED_00406 1.7e-25
MHMNNKED_00407 6.7e-94 phaB 5.3.3.14, 5.3.3.18 I Enoyl-CoA hydratase/isomerase
MHMNNKED_00408 4.3e-110 yngG 4.1.3.4 E Hydroxymethylglutaryl-CoA lyase
MHMNNKED_00409 1.6e-176 C acyl-CoA transferases carnitine dehydratase
MHMNNKED_00410 1.7e-173 I Acyl-CoA dehydrogenase, C-terminal domain
MHMNNKED_00411 8.7e-187 yfkN 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MHMNNKED_00412 7.3e-75 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHMNNKED_00413 2.1e-96 T Transcriptional regulatory protein, C terminal
MHMNNKED_00414 4.8e-113 T PhoQ Sensor
MHMNNKED_00415 6.9e-239 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHMNNKED_00416 1.3e-65 ymaD O redox protein, regulator of disulfide bond formation
MHMNNKED_00417 2.4e-100 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_00418 1.1e-133 T PhoQ Sensor
MHMNNKED_00419 5.1e-123 V ABC transporter, ATP-binding protein
MHMNNKED_00420 4.9e-220 V ABC transporter (permease)
MHMNNKED_00421 2e-78 5.1.1.12 E Alanine racemase, N-terminal domain
MHMNNKED_00422 2.6e-92 livM E Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_00423 9.8e-117 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MHMNNKED_00424 1.9e-95 livF E Amino acid ABC transporter ATPase
MHMNNKED_00425 2.2e-50 lytE2 M Putative peptidoglycan binding domain
MHMNNKED_00426 8.8e-66 K acetyltransferase
MHMNNKED_00427 2.5e-203 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MHMNNKED_00428 3.3e-42 M Lysin motif
MHMNNKED_00429 3.8e-70 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MHMNNKED_00430 2.9e-49 mcpA NT Chemotaxis
MHMNNKED_00431 2.6e-42 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Low molecular weight phosphatase family
MHMNNKED_00432 7.2e-50 mntP P Probably functions as a manganese efflux pump
MHMNNKED_00433 1.3e-145 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHMNNKED_00434 2.1e-71 spoIIR S stage II sporulation protein R
MHMNNKED_00435 3.2e-108 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHMNNKED_00436 9.3e-171 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHMNNKED_00437 4.4e-88 tdk 2.7.1.21 F thymidine kinase
MHMNNKED_00438 2.5e-104 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHMNNKED_00439 4.2e-52 S Diphthamide synthase
MHMNNKED_00440 4e-119 yrdQ K Bacterial regulatory helix-turn-helix protein, lysR family
MHMNNKED_00441 3.3e-127 yrdR EG EamA-like transporter family
MHMNNKED_00442 3.7e-196 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHMNNKED_00443 1.4e-98 sdaAB 4.3.1.17 E L-serine dehydratase
MHMNNKED_00444 3.4e-94 S protein conserved in bacteria
MHMNNKED_00445 1.1e-132 glsA 3.5.1.2 E Belongs to the glutaminase family
MHMNNKED_00447 1.2e-39 S Domain of unknown function (DUF3870)
MHMNNKED_00448 4.2e-177 S Protein of unknown function (DUF819)
MHMNNKED_00449 5.1e-145 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHMNNKED_00450 1.3e-158 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHMNNKED_00451 2.4e-108 purC 6.3.2.6 F Phosphoribosylaminoimidazole-succinocarboxamide synthase
MHMNNKED_00452 6.8e-152 ddh 1.4.1.16 E Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MHMNNKED_00453 8e-154 1.2.1.3 C Aldehyde dehydrogenase family
MHMNNKED_00454 7.4e-45 K Acetyltransferase (GNAT) domain
MHMNNKED_00455 2.1e-213 XK27_10205
MHMNNKED_00456 9.2e-33
MHMNNKED_00457 2.9e-85 V AAA domain, putative AbiEii toxin, Type IV TA system
MHMNNKED_00458 6.8e-50 6.3.5.6, 6.3.5.7 J amidotransferase, A subunit
MHMNNKED_00459 5.7e-81 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHMNNKED_00460 5.1e-42 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHMNNKED_00462 6.7e-112 pstS P Phosphate
MHMNNKED_00463 5.4e-133 pstC P probably responsible for the translocation of the substrate across the membrane
MHMNNKED_00464 4.1e-116 pstA P Phosphate transport system permease
MHMNNKED_00465 1e-129 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHMNNKED_00466 1.7e-61 phoU P Plays a role in the regulation of phosphate uptake
MHMNNKED_00467 2.6e-11 yfhD S YfhD-like protein
MHMNNKED_00469 2e-42 recX 2.4.1.337 GT4 S Modulates RecA activity
MHMNNKED_00470 5.1e-35 yfhH S Protein of unknown function (DUF1811)
MHMNNKED_00471 1.1e-14 sspK S reproduction
MHMNNKED_00472 1.4e-141 yfhP S membrane-bound metal-dependent
MHMNNKED_00473 2.3e-148 mutY L A G-specific
MHMNNKED_00474 7.7e-27 yfhS
MHMNNKED_00475 6.2e-113 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHMNNKED_00477 1.4e-90 ygaC J Belongs to the UPF0374 family
MHMNNKED_00478 3.3e-258 ygaD V ABC transporter
MHMNNKED_00479 1.1e-126 ygaE S Membrane
MHMNNKED_00480 4.9e-19 P Ion transport
MHMNNKED_00481 2.6e-69 bcp 1.11.1.15 O Peroxiredoxin
MHMNNKED_00482 1.4e-117 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHMNNKED_00483 8.6e-72 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
MHMNNKED_00484 3.6e-68 perR P Belongs to the Fur family
MHMNNKED_00485 3.6e-39 ygzB S UPF0295 protein
MHMNNKED_00486 1.8e-103 ygxA S Nucleotidyltransferase-like
MHMNNKED_00488 1e-14 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
MHMNNKED_00489 2.4e-155 yfiF5 K AraC-like ligand binding domain
MHMNNKED_00490 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MHMNNKED_00491 1.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHMNNKED_00492 2e-241 dapL 2.6.1.83 E Aminotransferase class I and II
MHMNNKED_00493 1.2e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHMNNKED_00494 2.5e-258 glnA 6.3.1.2 E glutamine synthetase
MHMNNKED_00495 0.0 asnO 6.3.5.4 E Asparagine synthase
MHMNNKED_00496 1.4e-229 amtB P Ammonium transporter
MHMNNKED_00497 1.4e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHMNNKED_00498 1.6e-185 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
MHMNNKED_00499 3.2e-122 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
MHMNNKED_00500 4.3e-251 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHMNNKED_00501 2e-107 M1-161 T HD domain
MHMNNKED_00502 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHMNNKED_00503 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHMNNKED_00504 5.4e-161 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHMNNKED_00505 2.1e-21 yaaA S S4 domain
MHMNNKED_00506 1.8e-164 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHMNNKED_00507 4e-219 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHMNNKED_00508 2.2e-13 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MHMNNKED_00509 9.4e-40 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHMNNKED_00510 1.2e-82 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHMNNKED_00511 3.1e-70 jag S single-stranded nucleic acid binding R3H
MHMNNKED_00512 3.2e-208 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHMNNKED_00513 1.5e-309 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHMNNKED_00514 1.2e-86 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHMNNKED_00515 9e-116 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHMNNKED_00516 3e-123 soj D COG1192 ATPases involved in chromosome partitioning
MHMNNKED_00517 1.7e-119 spo0J K Belongs to the ParB family
MHMNNKED_00518 1.3e-80 ydfK S Protein of unknown function (DUF554)
MHMNNKED_00519 1.6e-82 yyaC S Sporulation protein YyaC
MHMNNKED_00520 2e-26 yyzM S protein conserved in bacteria
MHMNNKED_00521 1.4e-177 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHMNNKED_00522 3.3e-38 rpsF J Binds together with S18 to 16S ribosomal RNA
MHMNNKED_00523 1.3e-60 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHMNNKED_00524 4e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHMNNKED_00525 2.4e-29
MHMNNKED_00526 1.6e-33 C 4Fe-4S binding domain
MHMNNKED_00527 1.9e-181 mepA V MATE efflux family protein
MHMNNKED_00528 1.9e-84 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHMNNKED_00529 1.8e-43 gerD S Spore gernimation protein
MHMNNKED_00530 3.7e-53 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MHMNNKED_00531 1.6e-16 gerPF S Spore germination protein gerPA/gerPF
MHMNNKED_00532 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MHMNNKED_00533 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MHMNNKED_00534 1.3e-66 EGP Major facilitator Superfamily
MHMNNKED_00535 9.3e-70 yhjE S SNARE associated Golgi protein
MHMNNKED_00536 2.1e-45
MHMNNKED_00537 5.7e-56 comK K Competence transcription factor
MHMNNKED_00538 4.9e-08 S IDEAL
MHMNNKED_00539 3.6e-150 yhfN 3.4.24.84 O Peptidase M48
MHMNNKED_00540 9.5e-28 azlD S branched-chain amino acid
MHMNNKED_00541 2.2e-19 azlC E branched-chain amino acid
MHMNNKED_00542 1.8e-21 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHMNNKED_00543 1.2e-39 fliJ N Flagellar biosynthesis chaperone
MHMNNKED_00544 1.2e-07 ylxF S MgtE intracellular N domain
MHMNNKED_00545 2.3e-27 fliK N Flagellar hook-length control
MHMNNKED_00546 5.4e-49 flgD N Flagellar basal body rod modification protein
MHMNNKED_00547 2.1e-32 flg N Putative flagellar
MHMNNKED_00548 2.8e-72 flgE N flagellar
MHMNNKED_00549 3.6e-19 flbD N protein, possibly involved in motility
MHMNNKED_00550 1.7e-35 fliL N Controls the rotational direction of flagella during chemotaxis
MHMNNKED_00551 9.7e-138 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHMNNKED_00552 1.4e-130 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHMNNKED_00553 1.3e-52 cheY T Chemotaxis protein CheY
MHMNNKED_00554 3.1e-31 fliZ N Flagellar biosynthesis protein, FliO
MHMNNKED_00555 5.1e-95 fliP N Plays a role in the flagellum-specific transport system
MHMNNKED_00556 1.2e-26 fliQ N Role in flagellar biosynthesis
MHMNNKED_00557 1.5e-88 fliR N Flagellar biosynthetic protein FliR
MHMNNKED_00558 1.3e-119 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHMNNKED_00559 9.6e-302 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHMNNKED_00560 2.9e-114 flhF N Flagellar biosynthesis regulator FlhF
MHMNNKED_00561 8.9e-79 flhG D Belongs to the ParA family
MHMNNKED_00562 6.3e-119 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHMNNKED_00563 3.6e-264 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MHMNNKED_00564 2.3e-46 cheW NT COG0835 Chemotaxis signal transduction protein
MHMNNKED_00565 1e-71 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHMNNKED_00566 1.2e-59 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHMNNKED_00567 1.9e-96 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHMNNKED_00568 3.9e-13
MHMNNKED_00569 3.5e-21 ylxL
MHMNNKED_00570 1.8e-117 rpsB J Belongs to the universal ribosomal protein uS2 family
MHMNNKED_00571 4.3e-113 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHMNNKED_00572 1.2e-118 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHMNNKED_00573 2.2e-75 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHMNNKED_00574 4.4e-106 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHMNNKED_00575 3.5e-90 cdsA 2.7.7.41 S Belongs to the CDS family
MHMNNKED_00576 1.5e-155 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHMNNKED_00577 3.2e-186 rasP M zinc metalloprotease
MHMNNKED_00578 1.6e-262 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHMNNKED_00579 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHMNNKED_00580 7.2e-67 rimP S Required for maturation of 30S ribosomal subunits
MHMNNKED_00581 9.7e-182 nusA K Participates in both transcription termination and antitermination
MHMNNKED_00582 2.3e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
MHMNNKED_00583 1.3e-32 ylxQ J ribosomal protein
MHMNNKED_00584 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHMNNKED_00585 1.6e-29 ylxP S Protein of unknown function (DUF503)
MHMNNKED_00586 2.8e-47 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHMNNKED_00587 9.7e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHMNNKED_00588 2.8e-118 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHMNNKED_00589 1.2e-39 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHMNNKED_00590 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHMNNKED_00591 1.6e-126 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MHMNNKED_00592 2.6e-20 pgp-8 3.6.3.44 Q ATPase activity, coupled to transmembrane movement of substances
MHMNNKED_00593 7.1e-154 ymfD EGP Major facilitator Superfamily
MHMNNKED_00594 4.4e-55 yheN G deacetylase
MHMNNKED_00595 2.5e-29 K Cold shock
MHMNNKED_00596 3.9e-162 EG Bacillus/Clostridium GerA spore germination protein
MHMNNKED_00597 1.8e-76 E Spore germination protein
MHMNNKED_00598 5.9e-86 S Spore germination B3/ GerAC like, C-terminal
MHMNNKED_00600 2.7e-117 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHMNNKED_00601 3.7e-228 ligD 6.5.1.1 L ATP-dependent DNA ligase
MHMNNKED_00602 2.6e-53 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHMNNKED_00604 5.3e-211 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHMNNKED_00605 3.7e-256 araB 2.7.1.16 G Sugar (pentulose and hexulose) kinases
MHMNNKED_00606 1.8e-161 araR K helix_turn_helix gluconate operon transcriptional repressor
MHMNNKED_00607 6e-108 tcyC 3.6.3.21 E AAA domain, putative AbiEii toxin, Type IV TA system
MHMNNKED_00608 9e-74 tcyB P COG0765 ABC-type amino acid transport system, permease component
MHMNNKED_00609 2e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHMNNKED_00610 3.8e-143 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHMNNKED_00612 4.1e-22 P Copper resistance protein CopZ
MHMNNKED_00613 0.0 copA 3.6.3.54 P P-type ATPase
MHMNNKED_00614 5.4e-39 csoR S Metal-sensitive transcriptional repressor
MHMNNKED_00615 1e-196 1.7.2.1 Q Multicopper oxidase
MHMNNKED_00616 2.6e-99 yycG_2 T Histidine kinase
MHMNNKED_00617 3.6e-290 G Right handed beta helix region
MHMNNKED_00618 0.0 licR 2.7.1.202 K transcriptional regulator, MtlR
MHMNNKED_00619 2.2e-144 E Peptidase dimerisation domain
MHMNNKED_00620 1.8e-128 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M28
MHMNNKED_00621 3.4e-114 KT transcriptional regulatory protein
MHMNNKED_00622 2.8e-199 abgB S amidohydrolase
MHMNNKED_00623 2.6e-227 abgT H AbgT putative transporter family
MHMNNKED_00624 6.5e-171 abgA S Peptidase dimerisation domain
MHMNNKED_00626 7.3e-101 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
MHMNNKED_00627 9.7e-92 K Transcriptional regulator
MHMNNKED_00628 5.6e-48 S Uncharacterized protein conserved in bacteria (DUF2200)
MHMNNKED_00630 3.6e-227 MA20_18835 IQ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHMNNKED_00631 3.2e-24 bofA S Sigma-K factor-processing regulatory protein BofA
MHMNNKED_00632 7.8e-11 yaaL S Protein of unknown function (DUF2508)
MHMNNKED_00633 2.1e-100 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHMNNKED_00634 2.3e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHMNNKED_00635 5.1e-232 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHMNNKED_00636 2.7e-64 tadA 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHMNNKED_00637 6.3e-182 yaaH M Glycoside Hydrolase Family
MHMNNKED_00638 7.9e-69 dgk 2.7.1.113 F deoxyguanosine kinase
MHMNNKED_00639 1.3e-101 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MHMNNKED_00640 1.5e-08
MHMNNKED_00641 1.1e-191 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHMNNKED_00642 6.5e-166 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHMNNKED_00643 2.2e-247 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHMNNKED_00644 1.6e-100 yaaC S YaaC-like Protein
MHMNNKED_00645 8.1e-132 mviM S Oxidoreductase family, C-terminal alpha/beta domain
MHMNNKED_00646 2.2e-47 yoaS S Protein of unknown function (DUF2975)
MHMNNKED_00647 6.7e-28 yozG K Cro/C1-type HTH DNA-binding domain
MHMNNKED_00648 9.2e-79 S Protein of unknown function (DUF1657)
MHMNNKED_00649 8.6e-22 S Domain of unknown function (DUF4363)
MHMNNKED_00650 5.8e-09 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MHMNNKED_00651 3.2e-73 spoIIIAG S stage III sporulation protein AG
MHMNNKED_00652 2.7e-49 spoIIIAH S SpoIIIAH-like protein
MHMNNKED_00653 9.3e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHMNNKED_00654 1.8e-227 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHMNNKED_00655 9.2e-52 yqhY S protein conserved in bacteria
MHMNNKED_00656 8.5e-37 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHMNNKED_00657 4.7e-117 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHMNNKED_00658 2.4e-163 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHMNNKED_00659 5.6e-12 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHMNNKED_00660 1e-114 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHMNNKED_00661 1.6e-303 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHMNNKED_00662 7.2e-118 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MHMNNKED_00663 2.5e-61 argR K Regulates arginine biosynthesis genes
MHMNNKED_00664 5.2e-200 recN L May be involved in recombinational repair of damaged DNA
MHMNNKED_00665 1.5e-175 rseP 3.4.21.116 M Stage IV sporulation protein B
MHMNNKED_00666 4.7e-111 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHMNNKED_00667 7.2e-90 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHMNNKED_00668 2.2e-16 yqzF S Protein of unknown function (DUF2627)
MHMNNKED_00669 3.1e-205 bkdR KT Transcriptional regulator
MHMNNKED_00670 1.1e-166 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHMNNKED_00671 1.3e-183 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHMNNKED_00672 7.6e-143 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHMNNKED_00673 1.3e-171 bfmBAB 1.2.4.4 C Transketolase, pyrimidine binding domain
MHMNNKED_00674 4.9e-158 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHMNNKED_00675 6.4e-138 mutA 2.7.7.7, 5.4.99.2, 5.4.99.63 I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit
MHMNNKED_00676 0.0 mutB 5.4.99.2 I COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit
MHMNNKED_00677 4.4e-146 argK E periplasmic protein kinase ArgK and related GTPases of G3E family
MHMNNKED_00678 3.3e-65 yqjB S protein conserved in bacteria
MHMNNKED_00680 2.8e-65 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHMNNKED_00681 0.0 S Dynamin family
MHMNNKED_00682 1.9e-79 polA 2.7.7.7 L 5'3' exonuclease
MHMNNKED_00683 3.1e-97 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHMNNKED_00684 8.6e-10 sspL
MHMNNKED_00685 2.4e-52 rnhA 3.1.26.4 L Ribonuclease
MHMNNKED_00686 8e-159 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHMNNKED_00687 5.3e-82 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHMNNKED_00688 8.3e-298 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHMNNKED_00689 7.2e-117 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHMNNKED_00690 1.2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHMNNKED_00691 7.5e-145 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHMNNKED_00692 2.2e-47 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHMNNKED_00693 2.5e-49 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHMNNKED_00694 4.9e-158 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHMNNKED_00695 1.4e-254 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHMNNKED_00696 5.2e-94 tpiA 2.7.2.3, 5.1.3.39, 5.3.1.1, 5.3.1.33 G Triosephosphate isomerase
MHMNNKED_00697 1e-79 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
MHMNNKED_00698 5.1e-134 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
MHMNNKED_00699 2.2e-244 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHMNNKED_00700 4.3e-116 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHMNNKED_00702 1.1e-276 hsdR 3.1.21.3 L DEAD DEAH box helicase
MHMNNKED_00703 1.3e-20 tctC S Tripartite tricarboxylate transporter family receptor
MHMNNKED_00704 7.9e-131 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHMNNKED_00705 5.2e-236 S Tripartite tricarboxylate transporter TctA family
MHMNNKED_00706 1.6e-52 S Tripartite tricarboxylate transporter TctB family
MHMNNKED_00707 5.9e-83 citT T response regulator
MHMNNKED_00708 7.3e-156 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MHMNNKED_00709 2.8e-50 abrB S Transition state regulatory protein AbrB
MHMNNKED_00710 1.9e-76 yfkM 3.5.1.124 S protease
MHMNNKED_00711 3.7e-70 ywaF S Integral membrane protein
MHMNNKED_00712 3.1e-61 plsB 2.3.1.15 I Acyl-transferase
MHMNNKED_00713 5.3e-64 2.4.1.83 GT2 M glycosyl transferase family 2
MHMNNKED_00714 3.1e-83 mhqD S Phospholipase/Carboxylesterase
MHMNNKED_00715 7.3e-285 pepF2 E COG1164 Oligoendopeptidase F
MHMNNKED_00716 3.5e-175 2.6.1.113 H Aminotransferase class-III
MHMNNKED_00717 5.1e-201 E Amino acid permease
MHMNNKED_00718 7.7e-53 ysmB 2.4.2.28 K transcriptional
MHMNNKED_00719 2.4e-110 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHMNNKED_00720 2.1e-119 gerM S COG5401 Spore germination protein
MHMNNKED_00721 2.8e-81 K Acetyltransferase (GNAT) domain
MHMNNKED_00722 8e-73 FG adenosine 5'-monophosphoramidase activity
MHMNNKED_00724 1.6e-149 cstA_2 T Carbon starvation protein
MHMNNKED_00725 2.1e-89 2.3.1.57 J Acetyltransferase (GNAT) domain
MHMNNKED_00726 3.9e-49 E bleomycin resistance protein
MHMNNKED_00728 1.8e-127 yeaN P COG2807 Cyanate permease
MHMNNKED_00729 5.9e-73 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHMNNKED_00730 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHMNNKED_00731 4.2e-83 yegQ O Peptidase U32
MHMNNKED_00732 2e-196 yegQ O COG0826 Collagenase and related proteases
MHMNNKED_00733 2.6e-96 udk 2.7.1.48 F Cytidine monophosphokinase
MHMNNKED_00734 2.7e-69 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHMNNKED_00735 2.2e-233 pbpI 3.4.16.4 M Penicillin-binding Protein
MHMNNKED_00736 8.4e-43 yrrS S Protein of unknown function (DUF1510)
MHMNNKED_00737 1.3e-88 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHMNNKED_00739 3.9e-112 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHMNNKED_00740 3e-69 yqeG S hydrolase of the HAD superfamily
MHMNNKED_00741 1.5e-187 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHMNNKED_00742 3.5e-72 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHMNNKED_00743 5.1e-39 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MHMNNKED_00744 3.1e-80 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHMNNKED_00745 2.4e-69 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MHMNNKED_00746 2.9e-52 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHMNNKED_00747 9.8e-87 yqeM Q Methyltransferase
MHMNNKED_00748 2.6e-91 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHMNNKED_00749 2.9e-147 agcS E Sodium alanine symporter
MHMNNKED_00750 2.5e-90 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHMNNKED_00751 1.7e-49 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHMNNKED_00752 1.2e-110 opuAC E Glycine betaine ABC transporter
MHMNNKED_00753 3.8e-105 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHMNNKED_00754 5.8e-32 tetR7 K Bacterial regulatory proteins, tetR family
MHMNNKED_00755 2.1e-12 tetR7 K Bacterial regulatory proteins, tetR family
MHMNNKED_00756 7.2e-124 EG EamA-like transporter family
MHMNNKED_00757 3.7e-193 lytS 2.7.13.3 T Histidine kinase
MHMNNKED_00758 2e-76 lytT T COG3279 Response regulator of the LytR AlgR family
MHMNNKED_00759 3.5e-279 cstA_2 T Carbon starvation protein
MHMNNKED_00760 1.3e-108 XK27_05795 ET Ligated ion channel L-glutamate- and glycine-binding site
MHMNNKED_00761 3.6e-89 XK27_05795 E Binding-protein-dependent transport system inner membrane component
MHMNNKED_00762 1e-94 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHMNNKED_00763 5.4e-24 crh G Phosphocarrier protein Chr
MHMNNKED_00764 4.2e-135 whiA K May be required for sporulation
MHMNNKED_00765 3.1e-141 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MHMNNKED_00766 7.5e-134 rapZ S Displays ATPase and GTPase activities
MHMNNKED_00767 2.7e-55 yvcI 3.6.1.55 F Nudix hydrolase
MHMNNKED_00768 5.4e-162 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHMNNKED_00769 1.2e-95 S COG0457 FOG TPR repeat
MHMNNKED_00770 1.2e-94 K Bacterial regulatory helix-turn-helix protein, lysR family
MHMNNKED_00771 4.6e-229 hpaB 1.14.14.9 Q 4-hydroxyphenylacetate 3-hydroxylase C terminal
MHMNNKED_00772 1.3e-55 S Flavin reductase like domain
MHMNNKED_00773 5.2e-144 hpaD 1.13.11.2 E Glyoxalase bleomycin resistance protein dioxygenase
MHMNNKED_00774 3.8e-121 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHMNNKED_00775 2.4e-36 Q Tripartite ATP-independent periplasmic transporters, DctQ component
MHMNNKED_00776 2.1e-164 G Tripartite ATP-independent periplasmic transporter, DctM component
MHMNNKED_00777 1.1e-73 K FCD domain
MHMNNKED_00779 2.4e-225 hpaE 1.2.1.60 C Catalyzes the formation of betaine from betaine aldehyde
MHMNNKED_00780 2.8e-139 dapA 4.3.3.7 E Dihydrodipicolinate synthetase family
MHMNNKED_00781 1e-81 hpaG1 4.1.1.68 Q Fumarylacetoacetate (FAA) hydrolase family
MHMNNKED_00782 4.6e-108 hpaG 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase
MHMNNKED_00783 4.8e-45 hpcD 4.1.1.68, 5.3.3.10 E 5-carboxymethyl-2-hydroxymuconate isomerase
MHMNNKED_00784 4.3e-282 EU Dienelactone hydrolase family
MHMNNKED_00785 1.6e-155 norA EGP Major facilitator Superfamily
MHMNNKED_00786 3.6e-27 S YusW-like protein
MHMNNKED_00787 1e-113 spoIID D Stage II sporulation protein D
MHMNNKED_00788 1.7e-38 S VanZ like family
MHMNNKED_00789 1.6e-85 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MHMNNKED_00790 1.9e-73 yodN
MHMNNKED_00791 5.3e-20 yozE S Belongs to the UPF0346 family
MHMNNKED_00793 1.7e-70 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MHMNNKED_00794 6.1e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHMNNKED_00795 9.5e-253 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MHMNNKED_00796 1.5e-157 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MHMNNKED_00797 3.8e-127 desK 2.7.13.3 T Histidine kinase
MHMNNKED_00798 5.5e-31 bofC S BofC C-terminal domain
MHMNNKED_00799 7.4e-08 safA M spore coat assembly protein SafA
MHMNNKED_00800 9.9e-186 yisQ V Mate efflux family protein
MHMNNKED_00801 6.8e-84 S Domain of unknown function (DUF1906)
MHMNNKED_00802 7.7e-224 cstA T Carbon starvation protein
MHMNNKED_00804 4.4e-134 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
MHMNNKED_00806 9.1e-07
MHMNNKED_00807 3e-120 yjbB G Major Facilitator Superfamily
MHMNNKED_00808 1.7e-39 flgN NOU FlgN protein
MHMNNKED_00809 1.9e-24 flgM N factor) FlgM
MHMNNKED_00810 6.6e-48 yvyF S flagellar protein
MHMNNKED_00811 2.7e-76 comFC S Phosphoribosyl transferase domain
MHMNNKED_00812 1.6e-65 S Nuclease-related domain
MHMNNKED_00813 6.8e-212 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHMNNKED_00814 6.5e-119 degV S protein conserved in bacteria
MHMNNKED_00815 4.9e-104 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHMNNKED_00816 2.6e-139 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHMNNKED_00817 3.2e-94 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MHMNNKED_00818 1e-115 K Transcriptional regulator
MHMNNKED_00819 2.9e-114 galU 2.7.7.9 M Nucleotidyl transferase
MHMNNKED_00821 2.2e-123 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHMNNKED_00822 1.8e-146 CP COG1668 ABC-type Na efflux pump, permease component
MHMNNKED_00823 2.9e-131 ecsA_1 S ABC transporter, ATP-binding protein
MHMNNKED_00825 1.8e-100 V abc transporter atp-binding protein
MHMNNKED_00826 1.9e-41 yvoA_1 K GntR family transcriptional regulator
MHMNNKED_00827 3.6e-158 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHMNNKED_00828 0.0 odhA 1.2.4.2 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHMNNKED_00829 8e-234 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHMNNKED_00830 2.1e-172 EG COG2610 H gluconate symporter and related permeases
MHMNNKED_00831 1.5e-97 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MHMNNKED_00832 6.6e-24 S Spore germination B3/ GerAC like, C-terminal
MHMNNKED_00833 7e-109 M Peptidase family S41
MHMNNKED_00834 6.3e-40 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHMNNKED_00835 1.5e-216 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHMNNKED_00836 3.5e-70 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHMNNKED_00837 3.1e-82 rodA D Belongs to the SEDS family
MHMNNKED_00838 2.4e-12
MHMNNKED_00839 1.6e-179 nrnB S phosphohydrolase (DHH superfamily)
MHMNNKED_00840 1.5e-88 3.5.3.11 E Belongs to the arginase family
MHMNNKED_00841 5.6e-28
MHMNNKED_00842 2e-238 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHMNNKED_00843 1.5e-64 S Divergent PAP2 family
MHMNNKED_00844 1.7e-49 S Threonine/Serine exporter, ThrE
MHMNNKED_00845 9.1e-88 thrE S Putative threonine/serine exporter
MHMNNKED_00846 1.1e-46 queT S QueT transporter
MHMNNKED_00847 1.3e-47 S Bacterial PH domain
MHMNNKED_00848 3.1e-166 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHMNNKED_00849 5.7e-58 M1-874 K Domain of unknown function (DUF1836)
MHMNNKED_00850 5.4e-81 yplQ S protein, Hemolysin III
MHMNNKED_00851 0.0 L ABC transporter
MHMNNKED_00852 3.7e-183 hssS 2.7.13.3 T PhoQ Sensor
MHMNNKED_00853 8.6e-109 T Transcriptional regulatory protein, C terminal
MHMNNKED_00854 6e-188 spaC2 V Lanthionine synthetase C-like protein
MHMNNKED_00855 9.9e-236 spaT V AAA domain, putative AbiEii toxin, Type IV TA system
MHMNNKED_00858 2.6e-50 aprE 3.4.21.62 M Belongs to the peptidase S8 family
MHMNNKED_00859 4.7e-14 M COG3209 Rhs family protein
MHMNNKED_00860 1.1e-23 S Protein of unknown function (DUF2283)
MHMNNKED_00861 5.8e-77 4.4.1.3 S Cupin
MHMNNKED_00862 5.7e-99 S Uncharacterized protein conserved in bacteria (DUF2179)
MHMNNKED_00863 2.8e-28 cspD K 'Cold-shock' DNA-binding domain
MHMNNKED_00864 5e-150 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHMNNKED_00865 2.7e-61 ydaC Q Methyltransferase domain
MHMNNKED_00866 2e-121 S DNA/RNA non-specific endonuclease
MHMNNKED_00867 8.8e-73 proA_2 H Methyltransferase
MHMNNKED_00868 1.1e-52 S UPF0316 protein
MHMNNKED_00869 1.1e-18 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
MHMNNKED_00870 3.1e-66 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHMNNKED_00871 1.1e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHMNNKED_00872 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHMNNKED_00873 3e-210 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHMNNKED_00874 4.9e-219 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHMNNKED_00875 1.4e-42 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MHMNNKED_00876 2e-43 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MHMNNKED_00877 3.4e-39 ysxB J ribosomal protein
MHMNNKED_00878 5.1e-37 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHMNNKED_00879 3.3e-147 rng J ribonuclease, Rne Rng family
MHMNNKED_00880 8.8e-79 spoIVFB S Peptidase family M50
MHMNNKED_00881 3.2e-80 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MHMNNKED_00883 1.1e-116 ykgA E Amidinotransferase
MHMNNKED_00884 4.1e-123 minD D Belongs to the ParA family
MHMNNKED_00885 6.3e-72 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHMNNKED_00886 3.8e-40 mreD M shape-determining protein
MHMNNKED_00887 9.8e-105 mreC M Involved in formation and maintenance of cell shape
MHMNNKED_00888 1.3e-161 mreB D Rod shape-determining protein MreB
MHMNNKED_00889 9.8e-102 radC E Belongs to the UPF0758 family
MHMNNKED_00890 3e-59 maf D septum formation protein Maf
MHMNNKED_00891 4.8e-17 spoIIB
MHMNNKED_00892 2.2e-26 M RHS repeat-associated core domain protein
MHMNNKED_00894 1.7e-119 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHMNNKED_00895 3.1e-146 ykuI T Diguanylate phosphodiesterase
MHMNNKED_00896 2e-50 NT chemotaxis protein
MHMNNKED_00897 7.9e-130 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHMNNKED_00898 7.6e-09
MHMNNKED_00899 7.9e-117 S Polysaccharide biosynthesis protein
MHMNNKED_00900 9.1e-50 G WxcM-like, C-terminal
MHMNNKED_00901 1.2e-41 S Aminoglycoside phosphotransferase
MHMNNKED_00902 1.3e-64 comB 3.1.3.71 H 2-phosphosulpholactate phosphatase
MHMNNKED_00903 1.1e-110 livH E Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_00904 1.1e-128 livM E Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_00905 4.7e-108 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MHMNNKED_00906 6e-94 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MHMNNKED_00907 4e-151 livK E Receptor family ligand binding region
MHMNNKED_00908 1.2e-216 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MHMNNKED_00909 8.2e-243 ftsA D Cell division protein FtsA
MHMNNKED_00910 1.5e-159 ccpA K catabolite control protein A
MHMNNKED_00911 9.9e-101 motA N flagellar motor
MHMNNKED_00912 5.6e-85 motS N Flagellar motor protein
MHMNNKED_00913 2.4e-151 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHMNNKED_00914 1.8e-71 yvlB S Putative adhesin
MHMNNKED_00915 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHMNNKED_00916 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHMNNKED_00917 4.3e-15 csbA S Uncharacterized protein conserved in bacteria (DUF2198)
MHMNNKED_00918 1.2e-84 yjcH P COG2382 Enterochelin esterase and related enzymes
MHMNNKED_00919 1.1e-67 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MHMNNKED_00921 1.2e-31 spoVIF S Stage VI sporulation protein F
MHMNNKED_00922 1.7e-287 mcpC NT Cache domain
MHMNNKED_00923 2.5e-288 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
MHMNNKED_00924 7.1e-229 glnA 6.3.1.2 E glutamine synthetase
MHMNNKED_00925 8.6e-71 ribE 2.5.1.9 H Riboflavin synthase
MHMNNKED_00926 1.6e-74 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHMNNKED_00927 1.8e-65 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHMNNKED_00928 1.3e-115 ywqB S Zinc finger, swim domain protein
MHMNNKED_00929 4.8e-60
MHMNNKED_00930 4.3e-36 K Helix-turn-helix XRE-family like proteins
MHMNNKED_00931 1.7e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MHMNNKED_00932 4.7e-31 cspL K Cold shock
MHMNNKED_00933 1.5e-188 qor 1.6.5.5 C Zinc-binding dehydrogenase
MHMNNKED_00934 9.5e-43 yyaS S Membrane
MHMNNKED_00935 4.1e-59 ypbD S metal-dependent membrane protease
MHMNNKED_00936 4.3e-174 recQ 3.6.4.12 L DNA helicase
MHMNNKED_00937 2.6e-93 ypbB 5.1.3.1 S protein conserved in bacteria
MHMNNKED_00938 3.8e-35 fer C Ferredoxin
MHMNNKED_00939 4.5e-60 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHMNNKED_00940 5.1e-72 M COG0739 Membrane proteins related to metalloendopeptidases
MHMNNKED_00941 3.4e-41 rsiX
MHMNNKED_00942 3.1e-63 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MHMNNKED_00943 2.1e-212 resE 2.7.13.3 T Histidine kinase
MHMNNKED_00944 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_00945 2.8e-114 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHMNNKED_00946 3.2e-200 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
MHMNNKED_00947 7.5e-73 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHMNNKED_00950 1.3e-28 recJ L Single-stranded-DNA-specific exonuclease RecJ
MHMNNKED_00951 8e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHMNNKED_00952 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHMNNKED_00953 9.6e-58 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHMNNKED_00954 1.5e-09
MHMNNKED_00955 1e-200 hisS 6.1.1.21 J histidyl-tRNA synthetase
MHMNNKED_00956 6.4e-286 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHMNNKED_00958 1.6e-45 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
MHMNNKED_00959 8.5e-179 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHMNNKED_00960 1.4e-55 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
MHMNNKED_00961 2.6e-128 ybbH_2 K Transcriptional regulator
MHMNNKED_00963 1.4e-22 yozC
MHMNNKED_00964 1.9e-179 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHMNNKED_00966 1.9e-48 S Cupredoxin-like domain
MHMNNKED_00967 1.2e-30 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHMNNKED_00968 8.2e-10 6.1.1.7 S Threonyl and Alanyl tRNA synthetase second additional domain
MHMNNKED_00969 3e-14 alaS_2 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHMNNKED_00970 7.2e-70 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHMNNKED_00971 4.7e-79 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHMNNKED_00972 1.6e-129 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MHMNNKED_00973 7e-169 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHMNNKED_00975 9.4e-76 S Preprotein translocase subunit SecA (ATPase, RNA helicase)
MHMNNKED_00976 9e-146 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHMNNKED_00977 6.1e-125 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHMNNKED_00978 6.3e-84 tesE Q hydratase
MHMNNKED_00979 1.9e-79 EG EamA-like transporter family
MHMNNKED_00980 3.6e-152 nhaC C Na H antiporter
MHMNNKED_00981 2.4e-225 2.1.1.72, 3.1.21.4 V restriction endonuclease
MHMNNKED_00982 0.0 L T5orf172
MHMNNKED_00983 3e-160 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHMNNKED_00984 3.4e-198 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHMNNKED_00985 4.9e-118 rbsR K transcriptional
MHMNNKED_00986 1e-111 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHMNNKED_00987 9e-47 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHMNNKED_00988 8.2e-218 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHMNNKED_00989 6.1e-126 rbsC G Branched-chain amino acid transport system / permease component
MHMNNKED_00990 2.9e-117 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MHMNNKED_00991 2.7e-103 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHMNNKED_00992 6.7e-10
MHMNNKED_00993 3.1e-188 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHMNNKED_00994 4.4e-84 yuiC S protein conserved in bacteria
MHMNNKED_00995 2.1e-12 yuiB S Putative membrane protein
MHMNNKED_00996 9.9e-159 yumC 1.18.1.2, 1.19.1.1 C reductase
MHMNNKED_00997 8.3e-47 erpA S Belongs to the HesB IscA family
MHMNNKED_00998 1.6e-151 yutJ 1.6.99.3 C NADH dehydrogenase
MHMNNKED_00999 1.1e-254 L Integrase core domain
MHMNNKED_01000 1.3e-94 L PhoH-like protein
MHMNNKED_01001 1.1e-41 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MHMNNKED_01002 4.1e-23
MHMNNKED_01003 1.5e-198 yhbH S Belongs to the UPF0229 family
MHMNNKED_01004 0.0 prkA T Ser protein kinase
MHMNNKED_01005 8.1e-97 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MHMNNKED_01006 5.5e-78 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHMNNKED_01007 1.4e-111 yhbB S Putative amidase domain
MHMNNKED_01008 1.8e-177 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHMNNKED_01010 1.5e-45 yvoA K transcriptional
MHMNNKED_01011 6.7e-98 O peptidase U32
MHMNNKED_01012 1.7e-212 nagE 2.7.1.193, 2.7.1.199 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHMNNKED_01013 1.8e-41 crr 2.7.1.193, 2.7.1.199 G PTS glucose transporter subunit IIA
MHMNNKED_01014 1.6e-78 spmB S Spore maturation protein
MHMNNKED_01015 8.4e-89 spmA S Spore maturation protein
MHMNNKED_01016 1.1e-153 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MHMNNKED_01017 3.8e-68 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHMNNKED_01018 2.5e-90 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHMNNKED_01019 2e-42 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHMNNKED_01020 2.9e-198 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHMNNKED_01021 1.5e-208 spoVAF EG Stage V sporulation protein AF
MHMNNKED_01022 1.8e-24 spoVAB S Stage V sporulation protein AB
MHMNNKED_01023 1.7e-76 spoVAA S Stage V sporulation protein AA
MHMNNKED_01024 9.3e-117 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHMNNKED_01025 2e-63 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHMNNKED_01026 5.1e-41 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MHMNNKED_01027 2.3e-159 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MHMNNKED_01028 2.9e-12 EGP Major facilitator Superfamily
MHMNNKED_01030 8.1e-290 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHMNNKED_01031 2.3e-85 yuiD S Divergent PAP2 family
MHMNNKED_01032 2.1e-79 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MHMNNKED_01033 9.6e-158 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MHMNNKED_01034 6.6e-96 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MHMNNKED_01035 6.2e-51 3.1.3.73 G alpha-ribazole phosphatase activity
MHMNNKED_01036 1e-91 yitD 4.4.1.19 S synthase
MHMNNKED_01037 1.3e-176 yitG EGP Major facilitator Superfamily
MHMNNKED_01038 5.8e-33
MHMNNKED_01039 2.5e-103 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHMNNKED_01040 7e-42 pgpB 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHMNNKED_01041 5.6e-280 htpG O Molecular chaperone. Has ATPase activity
MHMNNKED_01042 5.1e-79 magIII L endonuclease III
MHMNNKED_01043 6.5e-116 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHMNNKED_01044 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHMNNKED_01045 2.1e-221 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHMNNKED_01046 1.6e-78 pncA Q COG1335 Amidases related to nicotinamidase
MHMNNKED_01047 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHMNNKED_01048 6.8e-60 ycnC K Bacterial regulatory proteins, tetR family
MHMNNKED_01049 7.1e-79 ykuK S Ribonuclease H-like
MHMNNKED_01050 8.7e-145 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHMNNKED_01051 5.5e-183 rocB E Peptidase family M20/M25/M40
MHMNNKED_01052 8.7e-255 siaT_1 S Tripartite ATP-independent periplasmic transporter, DctM component
MHMNNKED_01053 1.5e-32 S Domain of unknown function (DUF1850)
MHMNNKED_01054 1.1e-127 S NMT1-like family
MHMNNKED_01055 2.9e-156 1.1.1.1 C alcohol dehydrogenase
MHMNNKED_01056 1.7e-203 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHMNNKED_01057 6.4e-125 T PhoQ Sensor
MHMNNKED_01058 5e-75 L Integrase
MHMNNKED_01059 3e-50 yjcF S Acetyltransferase (GNAT) domain
MHMNNKED_01060 1.9e-83 ycgF3 E LysE type translocator
MHMNNKED_01061 3.1e-82 MTH_1382 S Membrane transport protein
MHMNNKED_01062 6e-106 cpoA GT4 M Glycosyltransferase Family 4
MHMNNKED_01064 2.8e-58 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHMNNKED_01065 2.5e-168 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHMNNKED_01066 2.1e-52 fld C Flavodoxin
MHMNNKED_01067 4e-73 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
MHMNNKED_01068 2.6e-143 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MHMNNKED_01069 5e-71 4.2.1.44 G Xylose isomerase-like TIM barrel
MHMNNKED_01070 2.3e-60 rpiB 5.3.1.34, 5.3.1.6 G Ribose 5-phosphate isomerase
MHMNNKED_01071 3.4e-74 K DeoR C terminal sensor domain
MHMNNKED_01072 1.6e-176 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
MHMNNKED_01073 6.7e-112 4.3.1.12 E Ornithine cyclodeaminase
MHMNNKED_01074 2.9e-157 dapL 2.6.1.83 E Aminotransferase
MHMNNKED_01075 6e-178 L Resolvase, N terminal domain
MHMNNKED_01076 1.3e-26 adaA 3.2.2.21 F Metal binding domain of Ada
MHMNNKED_01078 5.1e-82 1.16.3.2 P Ferritin-like domain
MHMNNKED_01080 3.7e-56 yugU S Uncharacterised protein family UPF0047
MHMNNKED_01082 8.4e-67 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHMNNKED_01083 4.9e-199 xylE EGP Sugar (and other) transporter
MHMNNKED_01084 4e-220 xylB 2.7.1.17 G xylulose kinase
MHMNNKED_01085 8.8e-70 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHMNNKED_01086 6.6e-105 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHMNNKED_01087 1.8e-124 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHMNNKED_01088 4.8e-122 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHMNNKED_01089 6.9e-54 rplQ J Ribosomal protein L17
MHMNNKED_01090 5.1e-157 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHMNNKED_01091 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHMNNKED_01092 3.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHMNNKED_01093 5.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHMNNKED_01094 1.1e-97 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHMNNKED_01095 1.4e-189 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHMNNKED_01096 8.2e-65 rplO J binds to the 23S rRNA
MHMNNKED_01097 1.2e-22 rpmD J Ribosomal protein L30
MHMNNKED_01098 2.1e-77 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHMNNKED_01099 5e-52 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHMNNKED_01100 1.6e-83 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHMNNKED_01101 1.1e-63 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHMNNKED_01102 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHMNNKED_01103 2.6e-89 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHMNNKED_01104 1.8e-42 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHMNNKED_01105 7.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHMNNKED_01106 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHMNNKED_01107 7.6e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MHMNNKED_01108 6.4e-70 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHMNNKED_01109 6e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHMNNKED_01110 2.2e-49 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHMNNKED_01111 1.6e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHMNNKED_01112 2.3e-145 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHMNNKED_01113 5e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHMNNKED_01114 6.7e-89 rplD J Forms part of the polypeptide exit tunnel
MHMNNKED_01115 9.5e-99 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHMNNKED_01116 2.2e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MHMNNKED_01117 2.1e-16
MHMNNKED_01118 1.7e-202 EGP Major facilitator Superfamily
MHMNNKED_01119 1.1e-63 K Transcriptional regulator
MHMNNKED_01120 1.8e-17 ywcB S Protein of unknown function, DUF485
MHMNNKED_01121 1.3e-139 yjjL G MFS/sugar transport protein
MHMNNKED_01122 3.8e-75 ydaF_1 J Acetyltransferase (GNAT) domain
MHMNNKED_01123 9.2e-128 tdcB_2 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MHMNNKED_01124 6.9e-61 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHMNNKED_01125 7.3e-156 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHMNNKED_01126 6.5e-181 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
MHMNNKED_01127 9.5e-102 ybbH_1 K RpiR family transcriptional regulator
MHMNNKED_01128 4.9e-174 EG COG2610 H gluconate symporter and related permeases
MHMNNKED_01129 1.3e-233 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHMNNKED_01131 1e-266 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHMNNKED_01132 4.1e-133 pbuG S permease
MHMNNKED_01133 1.3e-15 yebG S NETI protein
MHMNNKED_01134 3.1e-221 sftA D Belongs to the FtsK SpoIIIE SftA family
MHMNNKED_01135 7.8e-212 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MHMNNKED_01136 4.5e-08 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHMNNKED_01137 4.3e-12 XK27_07760 D gas vesicle protein
MHMNNKED_01138 3.1e-31 ytxJ O Protein of unknown function (DUF2847)
MHMNNKED_01139 2.8e-179 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHMNNKED_01140 9.3e-236 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MHMNNKED_01143 1e-212 E Sodium:solute symporter family
MHMNNKED_01144 1.3e-247 mtlF 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHMNNKED_01145 2.7e-166 mtlR K transcriptional regulator, MtlR
MHMNNKED_01146 1.1e-137 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHMNNKED_01147 6.2e-257 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHMNNKED_01149 1.8e-83 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHMNNKED_01150 1.5e-100 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
MHMNNKED_01151 1.7e-161 gntU EG GntP family permease
MHMNNKED_01152 1e-93 G Xylose isomerase-like TIM barrel
MHMNNKED_01153 2.5e-112 hprA 1.1.1.28, 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHMNNKED_01155 2.5e-154 G Major Facilitator Superfamily
MHMNNKED_01156 2.4e-114 yagE 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MHMNNKED_01157 2.6e-93 hag N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHMNNKED_01158 3.3e-165 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHMNNKED_01159 1.7e-25 3.4.21.107 O serine-type endopeptidase activity
MHMNNKED_01160 2e-240 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHMNNKED_01161 8.9e-20 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHMNNKED_01162 2.7e-102 polC 2.7.7.7 L 3' exoribonuclease, RNase T-like
MHMNNKED_01163 2.1e-210 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHMNNKED_01164 1.3e-78 S COG1647 Esterase lipase
MHMNNKED_01165 1.5e-176 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHMNNKED_01166 5e-156 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHMNNKED_01167 2.8e-92
MHMNNKED_01168 2.4e-147 mgtE P Acts as a magnesium transporter
MHMNNKED_01169 1.1e-192 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHMNNKED_01170 3.9e-154 rodA D Belongs to the SEDS family
MHMNNKED_01171 5.9e-45 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MHMNNKED_01173 4.4e-17
MHMNNKED_01174 9.3e-96 ysaA S HAD-hyrolase-like
MHMNNKED_01175 2.7e-169 yjcD 3.6.4.12 L Cold-inducible protein YdjO
MHMNNKED_01176 3e-12
MHMNNKED_01177 7e-20
MHMNNKED_01178 3.9e-128 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHMNNKED_01179 5.8e-36
MHMNNKED_01180 1.7e-20
MHMNNKED_01182 1.9e-64 yvgN S reductase
MHMNNKED_01183 9.4e-108 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHMNNKED_01184 4.8e-40 yhcU S Family of unknown function (DUF5365)
MHMNNKED_01185 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHMNNKED_01186 9.1e-95 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MHMNNKED_01187 4.3e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHMNNKED_01188 1.2e-192 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHMNNKED_01189 8.3e-21 ylqH S FlhB HrpN YscU SpaS Family
MHMNNKED_01190 4.1e-69 ylqG
MHMNNKED_01191 5.4e-91 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHMNNKED_01192 9e-124 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHMNNKED_01193 8.9e-69 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHMNNKED_01194 5.1e-54 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHMNNKED_01195 1.6e-113 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHMNNKED_01196 1.3e-69 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHMNNKED_01197 4.4e-38 ylqD S YlqD protein
MHMNNKED_01198 3.3e-20 ylqC S Belongs to the UPF0109 family
MHMNNKED_01199 1.5e-40 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHMNNKED_01200 2.8e-209 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHMNNKED_01201 1.4e-35 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHMNNKED_01202 1.2e-138 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHMNNKED_01203 2.7e-275 smc D Required for chromosome condensation and partitioning
MHMNNKED_01204 7.7e-95 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHMNNKED_01205 1.8e-29 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHMNNKED_01206 2e-100 IQ reductase
MHMNNKED_01207 3.7e-123 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHMNNKED_01208 5e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHMNNKED_01209 2.5e-77 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHMNNKED_01210 8.5e-298 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHMNNKED_01211 7.5e-236 yloV S kinase related to dihydroxyacetone kinase
MHMNNKED_01212 1.3e-52 asp S protein conserved in bacteria
MHMNNKED_01213 2.3e-24 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MHMNNKED_01214 3.2e-73 thiN 2.7.6.2 H thiamine pyrophosphokinase
MHMNNKED_01215 6.7e-103 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MHMNNKED_01216 9.4e-121 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHMNNKED_01217 1.3e-226 prkC 2.7.11.1 KLT serine threonine protein kinase
MHMNNKED_01218 1.8e-91 stp 3.1.3.16 T phosphatase
MHMNNKED_01219 5.5e-181 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHMNNKED_01220 4.5e-137 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHMNNKED_01221 8.4e-47 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHMNNKED_01222 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHMNNKED_01223 1.2e-161 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHMNNKED_01224 3.4e-13 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHMNNKED_01225 3.9e-97 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MHMNNKED_01226 5.5e-29 ylzA S Belongs to the UPF0296 family
MHMNNKED_01227 5.4e-76 yloC S stress-induced protein
MHMNNKED_01228 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MHMNNKED_01229 2.4e-237 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MHMNNKED_01230 4.1e-78 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHMNNKED_01231 6.5e-80 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHMNNKED_01232 2.5e-140 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHMNNKED_01233 1e-89 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHMNNKED_01234 0.0 carB 6.3.5.5 F Belongs to the CarB family
MHMNNKED_01235 3.1e-181 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHMNNKED_01236 5.3e-122 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHMNNKED_01237 2.3e-77 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHMNNKED_01238 3.7e-128 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHMNNKED_01239 4.3e-54 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHMNNKED_01240 3.7e-110 yppC S Protein of unknown function (DUF2515)
MHMNNKED_01243 7.4e-22 yppE S Bacterial domain of unknown function (DUF1798)
MHMNNKED_01244 1.6e-08 yppG S YppG-like protein
MHMNNKED_01245 1.1e-35 hspX O Belongs to the small heat shock protein (HSP20) family
MHMNNKED_01246 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHMNNKED_01247 7.4e-151 yprB L RNase_H superfamily
MHMNNKED_01248 3.7e-158 6.3.1.20 H Lipoate-protein ligase
MHMNNKED_01249 3.4e-100 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHMNNKED_01250 3.7e-11 yhfH S YhfH-like protein
MHMNNKED_01251 4.6e-142 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MHMNNKED_01252 2.6e-165 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHMNNKED_01253 7.3e-101 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHMNNKED_01254 6e-88 P COG2011 ABC-type metal ion transport system, permease component
MHMNNKED_01255 4.7e-106 metQ M Belongs to the nlpA lipoprotein family
MHMNNKED_01256 7.7e-166 abgB S amidohydrolase
MHMNNKED_01257 1.7e-108 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHMNNKED_01259 1.5e-11 K Helix-turn-helix XRE-family like proteins
MHMNNKED_01260 1.4e-13 3.2.1.8 S protein homooligomerization
MHMNNKED_01261 4.7e-206 helD_2 3.6.4.12 L DNA helicase
MHMNNKED_01262 3.8e-26 2.7.1.11 G alpha-ribazole phosphatase activity
MHMNNKED_01263 3.1e-252 gpmI 5.4.2.12 F Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHMNNKED_01264 9.4e-64 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHMNNKED_01265 3.2e-84 5.1.3.2 GT2 GM 3-beta hydroxysteroid dehydrogenase/isomerase family
MHMNNKED_01266 9.3e-131 rfbG 4.2.1.45 M Male sterility protein
MHMNNKED_01267 6e-111 rfbF 2.7.7.33 JM Glucose-1-phosphate cytidylyltransferase
MHMNNKED_01268 1.9e-11 O Tetratricopeptide repeat protein
MHMNNKED_01269 5.5e-66 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHMNNKED_01270 7.7e-71 IQ Enoyl-(Acyl carrier protein) reductase
MHMNNKED_01271 5.6e-79 3.5.1.124 S DJ-1/PfpI family
MHMNNKED_01272 3.3e-94 yniA G Fructosamine kinase
MHMNNKED_01273 5.5e-75 S reductase
MHMNNKED_01274 3.2e-171 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHMNNKED_01276 3.4e-95 M1-592 P ABC transporter, ATP-binding protein
MHMNNKED_01277 2.9e-89 ytlD1 P Binding-protein-dependent transport system inner membrane component
MHMNNKED_01278 5.3e-36 M1-594 S Thiamine-binding protein
MHMNNKED_01279 6.7e-139 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHMNNKED_01280 7.3e-83 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHMNNKED_01281 5.7e-40
MHMNNKED_01282 4.5e-171 traB S TraB family
MHMNNKED_01283 1.7e-136 ynfM EGP Major facilitator Superfamily
MHMNNKED_01287 4.5e-112 G protein with SCP PR1 domains
MHMNNKED_01288 1.5e-112 degV1 S Uncharacterised protein, DegV family COG1307
MHMNNKED_01291 4.1e-59 comEC L domain protein
MHMNNKED_01294 2.8e-32
MHMNNKED_01296 3.4e-73 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHMNNKED_01297 1.2e-90 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHMNNKED_01298 1.3e-104 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHMNNKED_01299 1.4e-199 E COG0747 ABC-type dipeptide transport system, periplasmic component
MHMNNKED_01300 7.4e-49 K helix_turn_helix gluconate operon transcriptional repressor
MHMNNKED_01301 1.4e-108 S Protein of unknown function (DUF1648)
MHMNNKED_01302 3.5e-159 S protein conserved in bacteria
MHMNNKED_01303 3.2e-31 M Belongs to the BCCT transporter (TC 2.A.15) family
MHMNNKED_01304 4.6e-159 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHMNNKED_01305 1.9e-99 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHMNNKED_01306 6.7e-186 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHMNNKED_01307 1.8e-62 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MHMNNKED_01308 1.8e-83 trpC 4.1.1.48, 5.3.1.24 E Indole-3-glycerol phosphate synthase
MHMNNKED_01309 1.8e-131 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHMNNKED_01310 3.6e-68 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MHMNNKED_01311 2.3e-166 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHMNNKED_01312 4.1e-81 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHMNNKED_01313 3.1e-13 S Putative adhesin
MHMNNKED_01315 1.6e-29
MHMNNKED_01316 4.2e-72 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHMNNKED_01317 1.4e-41 cotX S Spore Coat Protein X and V domain
MHMNNKED_01319 1.4e-61 yccU S CoA-binding protein
MHMNNKED_01321 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHMNNKED_01322 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHMNNKED_01323 2.5e-48 carD K Transcription factor
MHMNNKED_01324 9.4e-19 S Staygreen protein
MHMNNKED_01326 4.1e-09
MHMNNKED_01328 6.8e-79 rrmA 2.1.1.187 Q Methyltransferase
MHMNNKED_01329 6.8e-157 EGP Transmembrane secretion effector
MHMNNKED_01330 2.3e-128 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHMNNKED_01331 4.7e-231 yfbS P Sodium:sulfate symporter transmembrane region
MHMNNKED_01333 7.4e-68 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHMNNKED_01334 4.5e-75 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHMNNKED_01335 2.7e-114 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHMNNKED_01336 2.7e-145 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHMNNKED_01337 4.2e-258 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHMNNKED_01338 1.1e-72 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHMNNKED_01339 2e-101 ytpQ S Belongs to the UPF0354 family
MHMNNKED_01340 6.1e-41 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHMNNKED_01341 1.5e-60 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MHMNNKED_01342 4.6e-178 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MHMNNKED_01343 1e-21 ytzB S small secreted protein
MHMNNKED_01344 1.8e-132 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHMNNKED_01345 5.7e-102 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MHMNNKED_01346 1.4e-97 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHMNNKED_01347 3.5e-29 ytzH S YtzH-like protein
MHMNNKED_01348 2.6e-106 ytmP 2.7.1.89 M Phosphotransferase
MHMNNKED_01349 1.4e-90 ytlR 2.7.1.91 I Diacylglycerol kinase accessory domain
MHMNNKED_01350 4.3e-90 ytlQ
MHMNNKED_01351 5.6e-58 ligT 3.1.4.58, 3.5.1.42 J LigT like Phosphoesterase
MHMNNKED_01352 1.3e-26 ytzE K helix_turn_helix, Deoxyribose operon repressor
MHMNNKED_01353 1.2e-100 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHMNNKED_01355 1.2e-193 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHMNNKED_01356 1.7e-187 ytfP S HI0933-like protein
MHMNNKED_01357 3.8e-21 yteV S Sporulation protein Cse60
MHMNNKED_01358 3.5e-193 dppE_1 E Bacterial extracellular solute-binding proteins, family 5 Middle
MHMNNKED_01359 4.2e-36 ytwF P Sulfurtransferase
MHMNNKED_01360 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHMNNKED_01361 3.2e-131 fepC 3.6.3.34 HP ABC transporter
MHMNNKED_01362 1.6e-148 P FecCD transport family
MHMNNKED_01363 2e-154 fepD P FecCD transport family
MHMNNKED_01364 5.6e-144 P Periplasmic binding protein
MHMNNKED_01365 1.5e-154 ycgT 1.18.1.2, 1.19.1.1 C reductase
MHMNNKED_01366 3e-258 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHMNNKED_01367 3.5e-40 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHMNNKED_01368 1.8e-47 ydiL S CAAX protease self-immunity
MHMNNKED_01370 8.7e-83 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHMNNKED_01371 6.1e-91 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHMNNKED_01372 2e-256 yheS_3 S ABC transporter
MHMNNKED_01373 4.7e-299 clpE O Belongs to the ClpA ClpB family
MHMNNKED_01374 1.6e-116 ykvI S membrane
MHMNNKED_01375 1.1e-72 S CAAX protease self-immunity
MHMNNKED_01376 9.5e-20 ykvS S protein conserved in bacteria
MHMNNKED_01377 1e-14
MHMNNKED_01378 2.4e-67 3.5.1.28 M Cell Wall Hydrolase
MHMNNKED_01379 1.1e-24 ptsH G phosphocarrier protein HPr
MHMNNKED_01380 2.1e-128 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHMNNKED_01381 2.9e-57 ykyB S YkyB-like protein
MHMNNKED_01382 1.5e-107 ykuE S Metallophosphoesterase
MHMNNKED_01383 3.5e-07
MHMNNKED_01384 6.4e-27 O COG0695 Glutaredoxin and related proteins
MHMNNKED_01385 1.2e-28 ykuJ S protein conserved in bacteria
MHMNNKED_01386 3.6e-52 ykuL S COG0517 FOG CBS domain
MHMNNKED_01387 3.7e-141 ccpC K Transcriptional regulator
MHMNNKED_01388 1.2e-28 ykuS S Belongs to the UPF0180 family
MHMNNKED_01389 2.3e-08 csfB S Inhibitor of sigma-G Gin
MHMNNKED_01390 3.4e-80 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHMNNKED_01391 3.1e-48 yaaQ S protein conserved in bacteria
MHMNNKED_01392 1.3e-38 yaaR S protein conserved in bacteria
MHMNNKED_01393 5.8e-135 holB 2.7.7.7 L DNA polymerase III
MHMNNKED_01394 1.1e-126 yaaT S stage 0 sporulation protein
MHMNNKED_01395 1.6e-21 yabA L Involved in initiation control of chromosome replication
MHMNNKED_01396 3e-112 yabB 2.1.1.223 S Conserved hypothetical protein 95
MHMNNKED_01397 6.2e-29 yazA L endonuclease containing a URI domain
MHMNNKED_01398 5.1e-111 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHMNNKED_01399 1.5e-30 abrB K COG2002 Regulators of stationary sporulation gene expression
MHMNNKED_01400 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHMNNKED_01401 7.2e-117 tatD L hydrolase, TatD
MHMNNKED_01402 5.3e-21 fimV NU Tfp pilus assembly protein FimV
MHMNNKED_01403 5.8e-184 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHMNNKED_01404 1.3e-13 S Inner spore coat protein D
MHMNNKED_01405 8.5e-37 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHMNNKED_01406 2.2e-178 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MHMNNKED_01408 1.9e-26 S COG1734 DnaK suppressor protein
MHMNNKED_01409 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHMNNKED_01410 1.6e-38 divIVA D Cell division initiation protein
MHMNNKED_01411 4.6e-87 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MHMNNKED_01412 3.9e-22 yggT S membrane
MHMNNKED_01413 6.3e-44 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHMNNKED_01414 6e-91 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHMNNKED_01415 1.8e-89 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MHMNNKED_01416 1.4e-131 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHMNNKED_01417 1.3e-120 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHMNNKED_01418 1.7e-96 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHMNNKED_01419 8.7e-162 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHMNNKED_01420 2e-175 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHMNNKED_01421 1.1e-43 sbp S small basic protein
MHMNNKED_01422 2.4e-58 ylxX S protein conserved in bacteria
MHMNNKED_01423 1.7e-51 ylxW S protein conserved in bacteria
MHMNNKED_01424 1.1e-59 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHMNNKED_01425 5.1e-153 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHMNNKED_01426 9e-152 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHMNNKED_01428 1.4e-10
MHMNNKED_01429 5.7e-187 E Sodium:solute symporter family
MHMNNKED_01430 1.6e-124 yjbA S Belongs to the UPF0736 family
MHMNNKED_01431 1.6e-47 yjaZ O Zn-dependent protease
MHMNNKED_01432 4.4e-97 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
MHMNNKED_01433 2.8e-81 S lantibiotic protection ABC transporter permease subunit, MutE EpiE family
MHMNNKED_01434 3.5e-90 S ABC-2 family transporter protein
MHMNNKED_01435 6.9e-40
MHMNNKED_01436 1.3e-18 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
MHMNNKED_01437 2.7e-204 L Transposase domain (DUF772)
MHMNNKED_01440 5.3e-156 mmgC I acyl-CoA dehydrogenase
MHMNNKED_01441 2.6e-123 hbdA 1.1.1.157 I Dehydrogenase
MHMNNKED_01442 8.6e-186 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MHMNNKED_01443 0.0 fadF C COG0247 Fe-S oxidoreductase
MHMNNKED_01444 2.4e-119 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHMNNKED_01445 5.6e-263 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHMNNKED_01446 5.1e-38 ywiB S Domain of unknown function (DUF1934)
MHMNNKED_01447 1.6e-272 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHMNNKED_01448 8e-72 ywhD S YwhD family
MHMNNKED_01449 3.3e-78 ywhC S Peptidase M50
MHMNNKED_01450 1.3e-19 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MHMNNKED_01451 1.2e-67 ywgA 2.1.1.72, 3.1.21.3
MHMNNKED_01452 1.7e-214 ywfO S COG1078 HD superfamily phosphohydrolases
MHMNNKED_01453 1.3e-26 ywzC S Belongs to the UPF0741 family
MHMNNKED_01454 1.8e-74 rsfA S Transcriptional regulator
MHMNNKED_01455 5.3e-129 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHMNNKED_01456 2.1e-145 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MHMNNKED_01457 1.2e-108 ywfI C May function as heme-dependent peroxidase
MHMNNKED_01458 6.1e-113 ecsA V transporter (ATP-binding protein)
MHMNNKED_01459 6.3e-131 ecsB U ABC transporter
MHMNNKED_01460 1.7e-99 ecsC P EcsC protein family
MHMNNKED_01461 3.1e-175 yhaA E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHMNNKED_01462 3.5e-57 ymcC S Membrane
MHMNNKED_01463 2.6e-61 K BetI-type transcriptional repressor, C-terminal
MHMNNKED_01464 2.2e-84 engB D Necessary for normal cell division and for the maintenance of normal septation
MHMNNKED_01465 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHMNNKED_01466 8.4e-267 lonB 3.4.21.53 LO Belongs to the peptidase S16 family
MHMNNKED_01467 2.2e-208 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHMNNKED_01468 4.6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHMNNKED_01469 6.1e-76 trxA2 O COG0457 FOG TPR repeat
MHMNNKED_01471 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHMNNKED_01472 3.7e-99
MHMNNKED_01473 1.6e-34 KLT Protein tyrosine kinase
MHMNNKED_01474 1.5e-72 thyX 2.1.1.148 H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
MHMNNKED_01476 5.4e-64
MHMNNKED_01478 3e-43 gmk_1 2.7.4.8 F Guanylate kinase homologues.
MHMNNKED_01479 1.1e-57 E Psort location Cytoplasmic, score
MHMNNKED_01480 8.3e-253 aceB 2.3.3.9 C Belongs to the malate synthase family
MHMNNKED_01481 4.9e-211 aceA 4.1.3.1 C Isocitrate lyase
MHMNNKED_01482 3.6e-100 NT chemotaxis protein
MHMNNKED_01483 0.0 phaA 1.6.5.3 CP Domain of unknown function (DUF4040)
MHMNNKED_01484 1.1e-58 mnhB2 P Domain related to MnhB subunit of Na+/H+ antiporter
MHMNNKED_01485 5.6e-37 phaC 1.6.5.3 P NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
MHMNNKED_01486 1.9e-214 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01487 8.9e-57 mrpE P Na+/H+ ion antiporter subunit
MHMNNKED_01488 1.9e-27 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01489 1.9e-36 phaG P Mnh complex is a Na( ) H( ) antiporter involved in Na( ) excretion
MHMNNKED_01490 6.9e-91 4.2.1.17 I Enoyl-CoA hydratase/isomerase
MHMNNKED_01492 3.8e-50 ydiI Q protein, possibly involved in aromatic compounds catabolism
MHMNNKED_01493 3.8e-133 yuxJ EGP Major facilitator Superfamily
MHMNNKED_01494 7e-47 kapB G Kinase associated protein B
MHMNNKED_01495 5.1e-94 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHMNNKED_01496 5.8e-11
MHMNNKED_01497 2.3e-59 2.3.1.128 J Acetyltransferase (GNAT) domain
MHMNNKED_01498 8.5e-162 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHMNNKED_01499 6.8e-58 yugF I Hydrolase
MHMNNKED_01500 1e-89 I Enoyl-CoA hydratase/isomerase
MHMNNKED_01501 1.1e-65 alaR K Transcriptional regulator
MHMNNKED_01502 4.5e-182 yugH 2.6.1.1 E Aminotransferase
MHMNNKED_01503 1.9e-116 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHMNNKED_01504 1.9e-28 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHMNNKED_01506 2.2e-277 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHMNNKED_01507 3.4e-50 phnA P Alkylphosphonate utilization operon protein PhnA
MHMNNKED_01508 2.9e-133 pip S YhgE Pip N-terminal domain protein
MHMNNKED_01509 1.4e-81 fucA 4.1.2.17 G Aldolase
MHMNNKED_01510 2e-149 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHMNNKED_01511 9.9e-145 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHMNNKED_01512 2.5e-163 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHMNNKED_01513 4.2e-95 K Helix-turn-helix domain
MHMNNKED_01514 3.1e-29 2.3.1.57 J Acetyltransferase (GNAT) domain
MHMNNKED_01515 1.8e-83 K Bacterial regulatory proteins, tetR family
MHMNNKED_01516 7.5e-147 I Ndr family
MHMNNKED_01517 2e-73 yhbS S family acetyltransferase
MHMNNKED_01518 4.8e-38 K Transcriptional regulator PadR-like family
MHMNNKED_01519 1e-244 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHMNNKED_01520 3.2e-86 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MHMNNKED_01521 9.8e-100 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHMNNKED_01522 7e-84 artQ E Binding-protein-dependent transport system inner membrane component
MHMNNKED_01523 7.1e-80 artP ET Belongs to the bacterial solute-binding protein 3 family
MHMNNKED_01524 1.5e-202 sdaC E Tryptophan/tyrosine permease family
MHMNNKED_01525 1e-58 sdaAA 4.3.1.17 E L-serine dehydratase
MHMNNKED_01528 7e-86 S Spore germination B3/ GerAC like, C-terminal
MHMNNKED_01529 4.5e-88 E Spore germination protein
MHMNNKED_01532 3.9e-76 K Bacterial regulatory proteins, tetR family
MHMNNKED_01533 3.1e-203 EGP Major facilitator Superfamily
MHMNNKED_01534 5.4e-109 ribA 3.5.4.25, 4.1.99.12 H GTP cyclohydrolase II
MHMNNKED_01535 6.6e-148 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHMNNKED_01536 4.3e-61 3.1.3.3 E 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MHMNNKED_01537 8.9e-109 yeeN K transcriptional regulatory protein
MHMNNKED_01538 1.9e-166 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MHMNNKED_01539 6.7e-146 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHMNNKED_01540 3.3e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHMNNKED_01541 1.4e-92 csaB M Glycosyl Transferase
MHMNNKED_01542 3.3e-101 M Glycosyltransferase like family 2
MHMNNKED_01543 9.2e-10 yhaL S Sporulation protein YhaL
MHMNNKED_01544 5.8e-193 cbf S 3'-5' exoribonuclease yhaM
MHMNNKED_01545 1.6e-196 L AAA domain
MHMNNKED_01546 4.2e-127 yhaO L DNA repair exonuclease
MHMNNKED_01547 7e-128 3.4.24.84 O Peptidase family M48
MHMNNKED_01548 2.7e-17 S YhzD-like protein
MHMNNKED_01549 6e-171 yjlD 1.6.99.3 C NADH dehydrogenase
MHMNNKED_01550 1.6e-36 yjlC S Protein of unknown function (DUF1641)
MHMNNKED_01551 6.8e-258 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_01552 5.1e-103 yhaX S hydrolases of the HAD superfamily
MHMNNKED_01553 1e-30 yheA S Belongs to the UPF0342 family
MHMNNKED_01554 1e-98 yheB S Belongs to the UPF0754 family
MHMNNKED_01555 8.5e-52 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHMNNKED_01556 2.8e-69 yheC HJ YheC/D like ATP-grasp
MHMNNKED_01557 4.4e-141 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHMNNKED_01558 1.4e-66 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
MHMNNKED_01559 1.9e-23
MHMNNKED_01560 2.1e-23 sasP S Small, acid-soluble spore proteins, alpha/beta type
MHMNNKED_01561 3.3e-17 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHMNNKED_01562 1.7e-111 yqgE EGP Major facilitator superfamily
MHMNNKED_01563 1.4e-118 pdaA G deacetylase
MHMNNKED_01565 1.5e-113 yfkD S YfkD-like protein
MHMNNKED_01566 2e-142 yfkF EGP Major facilitator Superfamily
MHMNNKED_01567 9.6e-235 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MHMNNKED_01568 1.6e-101 yihY S Belongs to the UPF0761 family
MHMNNKED_01569 4.5e-10 yfkI S gas vesicle protein
MHMNNKED_01570 3.8e-60 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHMNNKED_01571 2.9e-18 yfkK S Belongs to the UPF0435 family
MHMNNKED_01572 1.6e-124 map 3.4.11.18 E Methionine aminopeptidase
MHMNNKED_01573 2.5e-38 yhdN S Domain of unknown function (DUF1992)
MHMNNKED_01574 1.4e-34 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MHMNNKED_01575 4.1e-162 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHMNNKED_01576 2.7e-38 ybjQ S Putative heavy-metal-binding
MHMNNKED_01577 5e-67 yvdA 4.2.1.1 P Reversible hydration of carbon dioxide
MHMNNKED_01578 1.7e-136 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHMNNKED_01579 2.7e-34 yrzB S Belongs to the UPF0473 family
MHMNNKED_01580 6.2e-54 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHMNNKED_01581 4.1e-35 yrzL S Belongs to the UPF0297 family
MHMNNKED_01582 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHMNNKED_01583 4.6e-125 yrrI S AI-2E family transporter
MHMNNKED_01584 4.2e-29 yrzR
MHMNNKED_01585 6.3e-35 fdxA C 4Fe-4S binding domain
MHMNNKED_01586 9.1e-157 mhqA 3.4.21.26 E COG0346 Lactoylglutathione lyase and related lyases
MHMNNKED_01587 1.4e-99 aatB ET Bacterial periplasmic substrate-binding proteins
MHMNNKED_01588 9.3e-89 artQ E COG0765 ABC-type amino acid transport system, permease component
MHMNNKED_01589 6e-100 glnQ3 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHMNNKED_01590 0.0 3.6.3.8 P COG0474 Cation transport ATPase
MHMNNKED_01591 1.4e-51 ywnF S Family of unknown function (DUF5392)
MHMNNKED_01592 4.6e-07 S Protein of unknown function (DUF1450)
MHMNNKED_01593 3.6e-99 cheV 2.7.13.3 T Chemotaxis protein CheV
MHMNNKED_01594 1.2e-107 yueF S transporter activity
MHMNNKED_01595 4.1e-43 yusN M Coat F domain
MHMNNKED_01596 1.2e-23
MHMNNKED_01597 1.6e-126 fadM E Proline dehydrogenase
MHMNNKED_01598 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MHMNNKED_01599 2e-182 fadA 2.3.1.16 I Belongs to the thiolase family
MHMNNKED_01600 1.4e-288 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MHMNNKED_01601 1.3e-52 arsC 1.20.4.1 P Belongs to the ArsC family
MHMNNKED_01602 3.4e-51 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHMNNKED_01603 4.1e-46 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MHMNNKED_01604 2.8e-35 yusE CO Thioredoxin
MHMNNKED_01605 1.3e-09 S SCP-2 sterol transfer family
MHMNNKED_01607 3.9e-142 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHMNNKED_01608 1.9e-89 metI P COG2011 ABC-type metal ion transport system, permease component
MHMNNKED_01609 4.2e-16 yafE Q ubiE/COQ5 methyltransferase family
MHMNNKED_01611 1.1e-08 ppsA2 2.7.9.2 GT Pyruvate phosphate dikinase, PEP/pyruvate binding domain
MHMNNKED_01612 2.8e-217 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHMNNKED_01613 3.2e-232 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHMNNKED_01614 5.4e-92 ktrA P COG0569 K transport systems, NAD-binding component
MHMNNKED_01615 1.4e-290 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHMNNKED_01616 8e-18 ykzG S Belongs to the UPF0356 family
MHMNNKED_01617 4.2e-33 recN L Putative cell-wall binding lipoprotein
MHMNNKED_01618 2.6e-158 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHMNNKED_01619 9e-165 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHMNNKED_01620 6.3e-58 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHMNNKED_01621 3.6e-29 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHMNNKED_01622 2.2e-34 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHMNNKED_01623 7.5e-139 speB 3.5.3.11 E Belongs to the arginase family
MHMNNKED_01624 1.3e-143 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHMNNKED_01625 1.3e-64 speH 2.5.1.128, 2.5.1.16, 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHMNNKED_01626 7.5e-211 speA 4.1.1.19 E decarboxylase
MHMNNKED_01627 2.5e-177 metK 2.5.1.6 H S-adenosylmethionine synthetase, C-terminal domain
MHMNNKED_01628 6.3e-227 G Major Facilitator Superfamily
MHMNNKED_01629 1.8e-26 yrzD S Post-transcriptional regulator
MHMNNKED_01630 5.4e-204 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHMNNKED_01631 3.5e-64 yrbG S membrane
MHMNNKED_01632 3.7e-45 yrzE S Protein of unknown function (DUF3792)
MHMNNKED_01633 1.8e-22 yajC U Preprotein translocase subunit YajC
MHMNNKED_01634 4.4e-203 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHMNNKED_01635 9.2e-160 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHMNNKED_01636 2.4e-19 yrzS S Protein of unknown function (DUF2905)
MHMNNKED_01637 2.8e-161 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHMNNKED_01638 5.3e-75 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHMNNKED_01639 3.8e-87 hprK T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHMNNKED_01640 8.8e-129 cydA 1.10.3.14 C oxidase, subunit
MHMNNKED_01641 1.4e-160 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHMNNKED_01642 5.3e-62 mta K MerR family transcriptional regulator
MHMNNKED_01643 3.8e-194 yaaH M Glyco_18
MHMNNKED_01644 0.0 S S-layer homology domain
MHMNNKED_01645 9.8e-190 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHMNNKED_01646 1.5e-120 S Aldo/keto reductase family
MHMNNKED_01647 9.1e-69 CO Thioredoxin
MHMNNKED_01648 5.2e-71 S Bax inhibitor 1 like
MHMNNKED_01649 2.3e-241 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHMNNKED_01650 1.1e-148 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHMNNKED_01651 1.5e-09 K Belongs to the sigma-70 factor family. ECF subfamily
MHMNNKED_01652 7.6e-58
MHMNNKED_01653 9.5e-09
MHMNNKED_01654 1.6e-34 I SCP-2 sterol transfer family
MHMNNKED_01655 8.1e-72 S Psort location CytoplasmicMembrane, score
MHMNNKED_01656 9.4e-73
MHMNNKED_01657 5.7e-182 2.3.1.9 I Thiolase, N-terminal domain
MHMNNKED_01658 7.3e-109 IQ Enoyl-(Acyl carrier protein) reductase
MHMNNKED_01659 7e-199 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
MHMNNKED_01660 4.9e-48 I MaoC like domain
MHMNNKED_01661 4.8e-60 MA20_04520 4.2.1.153, 4.2.1.56 S N-terminal half of MaoC dehydratase
MHMNNKED_01662 3.3e-114 IQ Enoyl-(Acyl carrier protein) reductase
MHMNNKED_01663 2.5e-172 mmgC_3 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
MHMNNKED_01664 1.6e-131 yjjC V COG1131 ABC-type multidrug transport system, ATPase component
MHMNNKED_01665 5.3e-67 K Bacterial regulatory proteins, tetR family
MHMNNKED_01666 3.1e-102
MHMNNKED_01667 4.5e-276 H ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHMNNKED_01668 6.5e-139 2.1.1.113 L Belongs to the N(4) N(6)-methyltransferase family
MHMNNKED_01669 4e-125 G Transmembrane secretion effector
MHMNNKED_01672 2.7e-112 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MHMNNKED_01673 2.1e-47 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MHMNNKED_01674 1.3e-105 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHMNNKED_01675 9.5e-60 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MHMNNKED_01676 7.9e-152 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHMNNKED_01677 4.2e-140 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHMNNKED_01678 1.3e-131 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHMNNKED_01679 1.5e-112 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHMNNKED_01680 1.2e-107 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHMNNKED_01681 2e-51 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHMNNKED_01682 2.6e-74 plsC 2.3.1.51 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
MHMNNKED_01683 4.9e-201 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHMNNKED_01684 3.4e-167 yfiB3 V ABC transporter transmembrane region
MHMNNKED_01685 1.2e-92 1.1.1.3 E homoserine dehydrogenase
MHMNNKED_01686 3.6e-201 metY 2.5.1.49 E O-acetylhomoserine
MHMNNKED_01687 1.6e-100 dksA T COG1734 DnaK suppressor protein
MHMNNKED_01689 4.6e-44 S Protein of unknown function (DUF2512)
MHMNNKED_01690 2.5e-84 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHMNNKED_01691 3e-106 EGP Major facilitator Superfamily
MHMNNKED_01692 9.6e-120 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHMNNKED_01693 3.2e-115 pstA P Phosphate transport system permease
MHMNNKED_01694 5.4e-124 pstC U probably responsible for the translocation of the substrate across the membrane
MHMNNKED_01695 3.3e-107 pstS P Phosphate ABC transporter substrate-binding protein
MHMNNKED_01697 4.5e-95 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHMNNKED_01698 3.5e-184 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
MHMNNKED_01699 2.4e-180 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
MHMNNKED_01700 1.5e-152 amacr C acyl-CoA transferases carnitine dehydratase
MHMNNKED_01701 2.1e-137 1.13.12.16 S Nitronate monooxygenase
MHMNNKED_01703 6e-33
MHMNNKED_01704 1e-23
MHMNNKED_01705 7.3e-109 M Glycosyl transferase family 2
MHMNNKED_01706 4.1e-142 S slime layer polysaccharide biosynthetic process
MHMNNKED_01707 1.7e-156 M COG0463, glycosyltransferases involved in cell wall biogenesis
MHMNNKED_01708 2.9e-10
MHMNNKED_01709 2.3e-35
MHMNNKED_01710 4.5e-71 V efflux transmembrane transporter activity
MHMNNKED_01711 3e-44 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHMNNKED_01712 8.7e-302 dnaK O Heat shock 70 kDa protein
MHMNNKED_01713 3.1e-148 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHMNNKED_01714 6e-142 prmA J Methylates ribosomal protein L11
MHMNNKED_01715 6.2e-81 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHMNNKED_01716 3.1e-232 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MHMNNKED_01717 2.5e-86 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHMNNKED_01718 1.6e-91 yqeW P COG1283 Na phosphate symporter
MHMNNKED_01719 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MHMNNKED_01720 4.4e-34 yqeY S Yqey-like protein
MHMNNKED_01721 3e-131 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MHMNNKED_01722 2.8e-84 yqfA S UPF0365 protein
MHMNNKED_01724 2.7e-37 yqfC S sporulation protein YqfC
MHMNNKED_01725 2.5e-148 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MHMNNKED_01726 3.9e-144 phoH T Phosphate starvation-inducible protein PhoH
MHMNNKED_01727 9.7e-268 yqfF S membrane-associated HD superfamily hydrolase
MHMNNKED_01728 2.9e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHMNNKED_01729 3.2e-25 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MHMNNKED_01730 8.9e-50 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHMNNKED_01731 4.2e-148 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHMNNKED_01732 1.7e-08 S YqzL-like protein
MHMNNKED_01733 7.5e-103 recO L Involved in DNA repair and RecF pathway recombination
MHMNNKED_01734 1.6e-93 ccpN K CBS domain
MHMNNKED_01735 1.4e-118 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHMNNKED_01736 3.5e-231 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHMNNKED_01737 3.6e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHMNNKED_01738 6.4e-178 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MHMNNKED_01739 8.8e-33 cccA C Cytochrome C oxidase, cbb3-type, subunit III
MHMNNKED_01740 5.1e-75 trmK 2.1.1.217 S SAM-dependent methyltransferase
MHMNNKED_01741 5.9e-168 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHMNNKED_01742 2.9e-152 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHMNNKED_01743 5.7e-30 yqfQ S YqfQ-like protein
MHMNNKED_01744 8.6e-179 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHMNNKED_01745 7.1e-148 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHMNNKED_01746 1.8e-24 yqfT S Protein of unknown function (DUF2624)
MHMNNKED_01747 3.6e-28 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHMNNKED_01748 3.4e-40 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHMNNKED_01749 2.7e-26 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHMNNKED_01750 2.5e-10 rpmC J Belongs to the universal ribosomal protein uL29 family
MHMNNKED_01751 5.2e-56 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHMNNKED_01752 1.6e-70 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHMNNKED_01753 2.8e-34 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHMNNKED_01754 1.3e-31 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHMNNKED_01755 6.7e-45 mce 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MHMNNKED_01756 2.2e-266 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHMNNKED_01757 3.2e-166 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MHMNNKED_01758 2.2e-184 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHMNNKED_01759 1.5e-224 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHMNNKED_01760 2.3e-236 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHMNNKED_01761 2.6e-129 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHMNNKED_01762 1.8e-88 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHMNNKED_01763 1.4e-94 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHMNNKED_01764 1.4e-09 S zinc-ribbon domain
MHMNNKED_01765 1.3e-43 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHMNNKED_01766 1.3e-89 S Abortive infection C-terminus
MHMNNKED_01767 1.5e-15 S Uncharacterized protein conserved in bacteria (DUF2188)
MHMNNKED_01768 2.9e-44 ygzB S UPF0295 protein
MHMNNKED_01769 3.4e-163 ygxA S Nucleotidyltransferase-like
MHMNNKED_01770 2.6e-115 glcT K antiterminator
MHMNNKED_01771 2.1e-183 S Alpha/beta hydrolase family
MHMNNKED_01772 3.2e-95 S Metallo-beta-lactamase superfamily
MHMNNKED_01773 2.4e-98 MA20_36880 CH FAD binding domain
MHMNNKED_01774 9.9e-37 emrR K Sugar-specific transcriptional regulator TrmB
MHMNNKED_01776 8.5e-159 garK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHMNNKED_01777 3.5e-98 murR K Helix-turn-helix domain, rpiR family
MHMNNKED_01778 1.7e-227 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MHMNNKED_01779 2e-32 M Sulfatase
MHMNNKED_01780 4.3e-21 S Pfam:DUF2029
MHMNNKED_01781 1.1e-38 S Acyltransferase family
MHMNNKED_01782 7.4e-36 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHMNNKED_01783 2.2e-61 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MHMNNKED_01784 2e-21 yazB K Helix-turn-helix XRE-family like proteins
MHMNNKED_01785 3.8e-25 rpsT J Binds directly to 16S ribosomal RNA
MHMNNKED_01786 5.5e-158 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHMNNKED_01787 1.6e-25 yqxA S Protein of unknown function (DUF3679)
MHMNNKED_01788 2.6e-135 4.2.1.115 M GDP-mannose 4,6 dehydratase
MHMNNKED_01789 5.2e-169 wecB 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHMNNKED_01790 5.4e-127 S Glycosyl transferases group 1
MHMNNKED_01792 3.1e-38 S Protein of unknown function (DUF1360)
MHMNNKED_01793 6e-54 S Spore coat protein Z
MHMNNKED_01794 1.9e-09
MHMNNKED_01795 7e-120 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MHMNNKED_01796 2.3e-189 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHMNNKED_01797 3.7e-14 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHMNNKED_01798 9e-43 xylA 5.3.1.5 G xylose isomerase activity
MHMNNKED_01799 1.1e-130 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHMNNKED_01800 1.1e-251 treP 2.7.1.201 G phosphotransferase system
MHMNNKED_01801 4.3e-276 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MHMNNKED_01802 1.3e-99 treR K transcriptional
MHMNNKED_01803 3.5e-273 3.2.1.10 GH13 G COG0366 Glycosidases
MHMNNKED_01805 5.8e-167 G ABC transporter substrate-binding protein
MHMNNKED_01806 7.2e-108 gltC K Transcriptional regulator
MHMNNKED_01807 3.8e-115 3.4.19.11 E Zn_pept
MHMNNKED_01808 5.9e-28 yhdB S YhdB-like protein
MHMNNKED_01809 1.2e-44 bdbC O Required for disulfide bond formation in some proteins
MHMNNKED_01810 1.6e-30 bdbA CO Thioredoxin
MHMNNKED_01811 1.5e-14 S nuclease activity
MHMNNKED_01812 1.7e-67 3.5.1.124 S DJ-1/PfpI family
MHMNNKED_01813 2e-160 ysfB KT regulator
MHMNNKED_01814 1.1e-42 V ABC transporter, ATP-binding protein
MHMNNKED_01815 7.4e-230 V FtsX-like permease family
MHMNNKED_01816 6.7e-46 adhC 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
MHMNNKED_01817 2.4e-150 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHMNNKED_01818 7.1e-108 ytkL S Belongs to the UPF0173 family
MHMNNKED_01819 1.4e-26 azlD S Branched-chain amino acid transport protein (AzlD)
MHMNNKED_01820 1.5e-66 ygaZ E AzlC protein
MHMNNKED_01822 2.7e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_01823 1.8e-176 T PhoQ Sensor
MHMNNKED_01824 5.3e-59 S Protein of unknown function (DUF3221)
MHMNNKED_01825 2.6e-103 mpr 3.4.21.19 E Belongs to the peptidase S1B family
MHMNNKED_01826 6.9e-25 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHMNNKED_01830 3.9e-70 yocA M Lysozyme-like
MHMNNKED_01831 2.2e-112 T Transcriptional regulatory protein, C terminal
MHMNNKED_01832 3.9e-173 yjcL S integral membrane protein
MHMNNKED_01833 4.8e-159 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHMNNKED_01834 1.9e-103 K Transcriptional regulator
MHMNNKED_01836 2.9e-91 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
MHMNNKED_01837 3.8e-102 ybbM S transport system, permease component
MHMNNKED_01838 1.3e-308 6.2.1.1 I AMP-dependent synthetase
MHMNNKED_01839 2.2e-46 M Protein of unknown function (DUF1541)
MHMNNKED_01840 2.2e-56 1.5.1.38 S FMN reductase
MHMNNKED_01841 3.7e-22
MHMNNKED_01842 4.2e-74 yieF S NAD(P)H-dependent FMN reductase
MHMNNKED_01843 8.4e-88 2.3.1.57 J Acetyltransferase (GNAT) domain
MHMNNKED_01844 1.5e-175 pbuO_1 S permease
MHMNNKED_01845 1.3e-86 S Protein of unknown function (DUF4256)
MHMNNKED_01846 3.1e-157 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MHMNNKED_01847 3.4e-62 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHMNNKED_01848 2.7e-83 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHMNNKED_01849 3.2e-95 yjbF S Competence protein
MHMNNKED_01850 3.7e-305 pepF E oligoendopeptidase F
MHMNNKED_01852 1.5e-140 lanM V Domain of unknown function (DUF4135)
MHMNNKED_01853 0.0 3.6.3.27 V ABC transporter transmembrane region
MHMNNKED_01854 5.1e-223 S Erythromycin esterase
MHMNNKED_01856 4.2e-97
MHMNNKED_01857 1.6e-44 cotB
MHMNNKED_01858 1.4e-43
MHMNNKED_01859 3.1e-71
MHMNNKED_01860 1.6e-188 P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHMNNKED_01861 3.9e-91 KT LytTr DNA-binding domain
MHMNNKED_01862 5.7e-218 lytS 2.7.13.3 T Histidine kinase
MHMNNKED_01863 1.2e-42 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHMNNKED_01864 1.3e-121 holA 2.7.7.7 L DNA polymerase III delta subunit
MHMNNKED_01866 5.4e-216 comEC S Competence protein ComEC
MHMNNKED_01867 2e-74 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
MHMNNKED_01868 6.9e-26 mod_1 2.1.1.72 L DNA methylase
MHMNNKED_01869 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
MHMNNKED_01870 1.2e-84 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHMNNKED_01871 3.4e-155 pdh 1.4.1.20, 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHMNNKED_01872 3.3e-152 bkdA1 1.2.4.1, 1.2.4.4 C 1-deoxy-D-xylulose-5-phosphate synthase
MHMNNKED_01873 1.9e-149 pdhB 1.2.4.1 C Transketolase, C-terminal domain
MHMNNKED_01874 5.1e-120 bkdB 1.8.1.4, 2.3.1.12, 2.3.1.168 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHMNNKED_01875 7.8e-157 lpdA 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MHMNNKED_01880 1.1e-96 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHMNNKED_01881 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHMNNKED_01882 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHMNNKED_01883 1.1e-57 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHMNNKED_01884 1.2e-109 MA20_23325 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHMNNKED_01885 1e-123 MA20_23330 P NMT1-like family
MHMNNKED_01887 1.8e-72 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHMNNKED_01889 2.8e-23 ddpX 3.4.13.22
MHMNNKED_01890 5.1e-37 ddpX 3.4.13.22 T protein conserved in bacteria
MHMNNKED_01894 3.1e-08 S growth of symbiont in host cell
MHMNNKED_01895 2e-227 ahpF O Alkyl hydroperoxide reductase
MHMNNKED_01896 1.8e-93 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MHMNNKED_01897 4.1e-12 S YuzL-like protein
MHMNNKED_01898 2.7e-33 tesC S Thioesterase-like superfamily
MHMNNKED_01900 3.2e-197 rnj S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHMNNKED_01905 1e-154 ydbT S Membrane
MHMNNKED_01906 3.7e-56 S Bacterial PH domain
MHMNNKED_01908 5.5e-22
MHMNNKED_01909 1.3e-34 S Protein of unknown function (DUF2089)
MHMNNKED_01910 1e-77 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHMNNKED_01911 8.8e-106 natA V COG1131 ABC-type multidrug transport system, ATPase component
MHMNNKED_01915 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHMNNKED_01916 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHMNNKED_01917 4.7e-74 rsmC 2.1.1.172 J Methyltransferase
MHMNNKED_01918 7.1e-46 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHMNNKED_01919 1.3e-71 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHMNNKED_01920 3.7e-96 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHMNNKED_01921 5e-67 rplK J Ribosomal protein L11/L12
MHMNNKED_01922 1.2e-81 nusG K Participates in transcription elongation, termination and antitermination
MHMNNKED_01923 1.9e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHMNNKED_01924 1.4e-95 sigH K Belongs to the sigma-70 factor family
MHMNNKED_01925 9.5e-59 yacP S RNA-binding protein containing a PIN domain
MHMNNKED_01926 1.8e-117 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHMNNKED_01927 1.5e-50 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHMNNKED_01928 4e-230 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHMNNKED_01929 2.8e-93 cysE 2.3.1.30 E Serine acetyltransferase
MHMNNKED_01930 1.6e-226 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHMNNKED_01931 1.3e-63 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHMNNKED_01932 4e-69 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHMNNKED_01933 2.7e-141 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MHMNNKED_01934 5.7e-205 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHMNNKED_01935 0.0 clpC O Belongs to the ClpA ClpB family
MHMNNKED_01936 4.4e-165 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHMNNKED_01937 3.5e-78 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MHMNNKED_01938 7e-59 ctsR K Belongs to the CtsR family
MHMNNKED_01939 6.8e-163 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHMNNKED_01940 5.1e-65 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHMNNKED_01941 1.7e-169 dnaB L Membrane attachment protein
MHMNNKED_01942 1.6e-126 dnaI L Primosomal protein DnaI
MHMNNKED_01943 3.7e-82 ytxC S YtxC-like family
MHMNNKED_01944 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHMNNKED_01945 1.1e-76 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHMNNKED_01946 9.7e-23 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MHMNNKED_01947 4.5e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHMNNKED_01948 8.8e-08 ysdA S membrane
MHMNNKED_01949 3.8e-39 L Phage integrase family
MHMNNKED_01950 3.6e-276 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHMNNKED_01951 9.4e-221 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHMNNKED_01952 3e-120 ybbR S protein conserved in bacteria
MHMNNKED_01953 1.7e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHMNNKED_01954 4.4e-72 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHMNNKED_01955 2.6e-84 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MHMNNKED_01956 9e-135 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHMNNKED_01957 1.4e-41 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MHMNNKED_01958 1.8e-33 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01959 3.3e-59 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01960 7.7e-208 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01961 7.3e-45 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01962 1.3e-56 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHMNNKED_01963 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHMNNKED_01966 4.9e-178 EGP Major facilitator Superfamily
MHMNNKED_01967 1.1e-106 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHMNNKED_01968 8.6e-18 S Uncharacterized protein conserved in bacteria (DUF2187)
MHMNNKED_01969 8.2e-114 M Glycosyl transferase family group 2
MHMNNKED_01970 7.7e-74 M Glycosyl transferase family group 2
MHMNNKED_01971 1.1e-38 V VanZ like family
MHMNNKED_01972 5.8e-76 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MHMNNKED_01973 2.1e-96 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHMNNKED_01974 1.7e-147 G Major Facilitator Superfamily
MHMNNKED_01975 6.8e-39 S alpha beta
MHMNNKED_01976 5.6e-126 yfmL L COG0513 Superfamily II DNA and RNA helicases
MHMNNKED_01978 2.1e-26 S Cyclopropane-fatty-acyl-phospholipid synthase
MHMNNKED_01979 2.6e-09 T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MHMNNKED_01980 7.5e-79 ydjA C Nitroreductase family
MHMNNKED_01981 5.4e-63 1.5.1.38 S FMN reductase
MHMNNKED_01982 4e-177 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHMNNKED_01984 1e-70 S Restriction endonuclease
MHMNNKED_01986 4.5e-09
MHMNNKED_01987 5.7e-23 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHMNNKED_01988 2.6e-197 C Luciferase-like monooxygenase
MHMNNKED_01989 6.3e-103 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHMNNKED_01990 2.4e-255 ggtA 2.3.2.2, 3.4.19.13 E Gamma-glutamyltranspeptidase
MHMNNKED_01991 1.1e-42 chrA P Chromate transporter
MHMNNKED_01992 8.9e-66 chrA P COG2059 Chromate transport protein ChrA
MHMNNKED_01993 1.8e-262 vpr O Belongs to the peptidase S8 family
MHMNNKED_01994 5e-34 atpI S ATP synthase I chain
MHMNNKED_01995 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
MHMNNKED_01996 3.2e-22 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHMNNKED_01997 1.6e-19 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHMNNKED_01998 1.6e-54 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHMNNKED_01999 1.9e-262 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHMNNKED_02000 6e-112 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHMNNKED_02001 5.2e-246 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHMNNKED_02002 8.2e-43 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHMNNKED_02003 2.3e-21 ywzB S membrane
MHMNNKED_02004 3.7e-57 ywmB S TATA-box binding
MHMNNKED_02005 2.6e-207 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHMNNKED_02014 2e-61 ydcK S Belongs to the SprT family
MHMNNKED_02015 0.0 yhgF K COG2183 Transcriptional accessory protein
MHMNNKED_02016 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MHMNNKED_02017 2.7e-37 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHMNNKED_02018 4.2e-121 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHMNNKED_02019 8.4e-145 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MHMNNKED_02020 8.1e-39 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHMNNKED_02021 6.6e-46 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MHMNNKED_02022 5e-48 uvsE L UV damage repair endonuclease UvdE
MHMNNKED_02023 2.2e-42 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MHMNNKED_02025 1.1e-151 ybfG M Domain of unknown function (DUF1906)
MHMNNKED_02027 1.3e-80 prsW S Involved in the degradation of specific anti-sigma factors
MHMNNKED_02028 4.5e-140 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MHMNNKED_02029 2.5e-215 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHMNNKED_02030 7.9e-28 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHMNNKED_02031 1.2e-55 ypbF S Protein of unknown function (DUF2663)
MHMNNKED_02033 2.2e-106 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
MHMNNKED_02034 3.5e-124 mvaD 4.1.1.33 I GHMP kinases N terminal domain
MHMNNKED_02035 1.6e-59 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
MHMNNKED_02036 6e-64 S AAA domain
MHMNNKED_02037 3e-88 yrkF OP Sulfurtransferase TusA
MHMNNKED_02038 5.3e-63 perX P Sulfur reduction protein DsrE
MHMNNKED_02039 2.1e-210 yrkH P Rhodanese Homology Domain
MHMNNKED_02040 6.2e-32 O Belongs to the sulfur carrier protein TusA family
MHMNNKED_02041 1.2e-106 S membrane transporter protein
MHMNNKED_02042 1.8e-35 yrkD S Metal-sensitive transcriptional repressor
MHMNNKED_02043 1.9e-43 P Rhodanese Homology Domain
MHMNNKED_02044 8.3e-38 P Rhodanese domain protein
MHMNNKED_02045 1.8e-80 T HD domain
MHMNNKED_02046 1.1e-82 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHMNNKED_02047 7.1e-21 ydcG K Helix-turn-helix domain
MHMNNKED_02048 1.2e-47 K Helix-turn-helix XRE-family like proteins
MHMNNKED_02049 1e-99 V ATPases associated with a variety of cellular activities
MHMNNKED_02050 1.8e-73 S ABC-2 family transporter protein
MHMNNKED_02051 1.1e-91 folE 3.5.4.16 H GTP cyclohydrolase
MHMNNKED_02052 3.8e-105 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHMNNKED_02053 5.7e-09 K sequence-specific DNA binding
MHMNNKED_02055 1.8e-54 E lipolytic protein G-D-S-L family
MHMNNKED_02056 4.7e-25 S GtrA-like protein
MHMNNKED_02057 5.5e-104 brnQ E Component of the transport system for branched-chain amino acids
MHMNNKED_02058 7.5e-37 brnQ E Component of the transport system for branched-chain amino acids
MHMNNKED_02059 2.2e-144 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MHMNNKED_02060 1.1e-13 cvfB S protein conserved in bacteria
MHMNNKED_02061 9e-160 mbl D Rod shape-determining protein
MHMNNKED_02062 1.3e-72
MHMNNKED_02063 3.2e-53 radC L RadC-like JAB domain
MHMNNKED_02064 9.3e-85 4.6.1.1 T Adenylate and Guanylate cyclase catalytic domain
MHMNNKED_02065 5.9e-25
MHMNNKED_02067 1.7e-39
MHMNNKED_02070 2.8e-17
MHMNNKED_02071 6.8e-54 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
MHMNNKED_02072 6.5e-66 1.8.5.2 S DoxX
MHMNNKED_02073 2.1e-107 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHMNNKED_02074 3.3e-77 S Sucrose-6F-phosphate phosphohydrolase
MHMNNKED_02075 2e-61 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHMNNKED_02076 8.4e-84 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHMNNKED_02077 2.4e-107 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MHMNNKED_02078 3.9e-66 thiW S Thiamine-precursor transporter protein (ThiW)
MHMNNKED_02079 6e-107 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHMNNKED_02080 1.1e-292 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHMNNKED_02081 7.9e-29 ypoC
MHMNNKED_02082 2.8e-109 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHMNNKED_02083 3.3e-92 dnaD L DNA replication protein DnaD
MHMNNKED_02084 1.7e-109 S ABC-2 family transporter protein
MHMNNKED_02085 9.3e-122 yxlF_1 V ABC transporter, ATP-binding protein
MHMNNKED_02086 6.8e-127 3.2.1.22 S NPCBM-associated, NEW3 domain of alpha-galactosidase
MHMNNKED_02087 8.6e-70 sigI K Sigma-70, region 4
MHMNNKED_02088 4e-45 rskA S Anti-sigma-K factor rskA
MHMNNKED_02089 4.3e-68 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MHMNNKED_02090 1.8e-72 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C alcohol dehydrogenase
MHMNNKED_02091 4.5e-66
MHMNNKED_02095 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MHMNNKED_02096 1.1e-83 kstR2_2 K Transcriptional regulator
MHMNNKED_02097 2.4e-131 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MHMNNKED_02098 3.7e-59 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHMNNKED_02099 3.8e-90 metI P Binding-protein-dependent transport system inner membrane component
MHMNNKED_02100 7.4e-83 metQ3 M Belongs to the nlpA lipoprotein family
MHMNNKED_02101 5.7e-156 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHMNNKED_02103 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHMNNKED_02104 3.4e-55 fld C Flavodoxin
MHMNNKED_02105 1.6e-164 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHMNNKED_02106 2.5e-263 S FAD binding domain
MHMNNKED_02107 3.3e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHMNNKED_02108 2.7e-210 pepV 3.5.1.18 E Dipeptidase
MHMNNKED_02109 1.9e-30 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MHMNNKED_02110 6.1e-232 mqo 1.1.5.4 C oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
MHMNNKED_02111 1.1e-124 nhaR K Transcriptional regulator
MHMNNKED_02112 3.3e-193 S F420-0:Gamma-glutamyl ligase
MHMNNKED_02113 2.1e-99 rluC 5.4.99.23, 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MHMNNKED_02114 4.5e-89 nagZ 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MHMNNKED_02115 2.6e-202 tagD 2.7.7.15, 2.7.7.39 H Oxidoreductase NAD-binding domain protein
MHMNNKED_02116 1.4e-41 M Glycosyl transferase, family 2
MHMNNKED_02117 2.7e-46 M transferase activity, transferring glycosyl groups
MHMNNKED_02118 6.3e-77 ptmE M Nucleotidyl transferase
MHMNNKED_02119 9.5e-47 ptmE M Nucleotidyl transferase
MHMNNKED_02120 4.4e-87 spoU 2.1.1.185 J RNA 2'-O ribose methyltransferase substrate binding
MHMNNKED_02121 3.8e-23 sspI S Small, acid-soluble spore protein I
MHMNNKED_02122 2e-58 slt M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHMNNKED_02123 8.4e-125 xerC L tyrosine recombinase XerC
MHMNNKED_02124 1.2e-78 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHMNNKED_02125 2.1e-215 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHMNNKED_02126 5.8e-122 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHMNNKED_02127 6.7e-34 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHMNNKED_02128 5.7e-58 flgC N Belongs to the flagella basal body rod proteins family
MHMNNKED_02129 1.1e-23 fliE N Flagellar hook-basal body
MHMNNKED_02130 2.3e-165 fliF N The M ring may be actively involved in energy transduction
MHMNNKED_02131 2.3e-155 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHMNNKED_02132 4.5e-34 fliH NU Flagellar assembly protein FliH
MHMNNKED_02133 2e-68 XK27_09665 5.4.2.11 G Phosphoglycerate mutase
MHMNNKED_02134 3.7e-67 yybS S membrane
MHMNNKED_02135 5.9e-264 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MHMNNKED_02136 5.1e-46 rplI J Binds to the 23S rRNA
MHMNNKED_02137 2e-218 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHMNNKED_02138 4e-124 nlpD M G5
MHMNNKED_02139 4.8e-46 EGP Major facilitator Superfamily
MHMNNKED_02140 1.3e-36 K Bacterial regulatory proteins, tetR family
MHMNNKED_02142 1e-170 clpB O Belongs to the ClpA ClpB family
MHMNNKED_02143 4.1e-56 rpfB GH23 T protein conserved in bacteria
MHMNNKED_02144 1.4e-69 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHMNNKED_02145 4.2e-121 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHMNNKED_02146 2.1e-128 yabG S peptidase
MHMNNKED_02147 2.3e-35 veg S protein conserved in bacteria
MHMNNKED_02148 3.6e-19 sspF S DNA topological change
MHMNNKED_02149 6.3e-56 opuAC E glycine betaine
MHMNNKED_02150 5.4e-85 ywaC 2.7.6.5 S Region found in RelA / SpoT proteins
MHMNNKED_02151 7.9e-125 dkgB S Aldo/keto reductase family
MHMNNKED_02152 4e-09 S Protein of unknown function (DUF4025)
MHMNNKED_02153 2e-108 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHMNNKED_02154 1.8e-191 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
MHMNNKED_02155 3.8e-146 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MHMNNKED_02156 1.4e-107 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHMNNKED_02157 4.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
MHMNNKED_02158 8.3e-210 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHMNNKED_02159 3.6e-238 rasP M zinc metalloprotease
MHMNNKED_02160 2.3e-20 S Domain of unknown function (DUF3899)
MHMNNKED_02161 1.1e-199 dppE_1 E Peptide ABC transporter substrate-binding protein
MHMNNKED_02162 1.2e-137 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHMNNKED_02163 2e-163 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHMNNKED_02164 2e-162 oppD P Belongs to the ABC transporter superfamily
MHMNNKED_02165 5.8e-153 oppF E Belongs to the ABC transporter superfamily
MHMNNKED_02166 4.1e-28
MHMNNKED_02167 6.2e-40 S Psort location CytoplasmicMembrane, score
MHMNNKED_02168 1.4e-13 S Domain of unknown function (DUF4430)
MHMNNKED_02169 1.7e-66 Q Thioesterase superfamily
MHMNNKED_02170 7.3e-96 zupT P Mediates zinc uptake. May also transport other divalent cations
MHMNNKED_02171 4.1e-23 uraA F Xanthine uracil
MHMNNKED_02172 2e-20
MHMNNKED_02174 4.5e-106 rpsA 1.17.7.4 J Ribosomal protein S1
MHMNNKED_02175 1.3e-33 yphA
MHMNNKED_02176 9e-127 seaA S YIEGIA protein
MHMNNKED_02177 7.5e-20 ypzH
MHMNNKED_02178 6.5e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MHMNNKED_02179 2.6e-141 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MHMNNKED_02180 2.6e-38 tagH 3.2.1.1, 3.5.1.28, 3.6.3.40 GH13 M N-acetylmuramoyl-L-alanine amidase
MHMNNKED_02181 3.3e-137 nifS 2.8.1.7 E Cysteine desulfurase
MHMNNKED_02182 3.1e-175 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MHMNNKED_02183 2.4e-113 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MHMNNKED_02184 8.7e-164 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHMNNKED_02185 4.2e-16 yphE S Protein of unknown function (DUF2768)
MHMNNKED_02186 1e-69 yphF
MHMNNKED_02187 2.7e-269 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHMNNKED_02188 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHMNNKED_02189 1.9e-28 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHMNNKED_02190 3.9e-52 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
MHMNNKED_02191 2.7e-110 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHMNNKED_02192 1.2e-137 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHMNNKED_02193 4.1e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHMNNKED_02194 7.3e-109 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MHMNNKED_02195 3.7e-165 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHMNNKED_02196 7e-97 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHMNNKED_02197 1.3e-139 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHMNNKED_02198 1.4e-87
MHMNNKED_02199 5.3e-133 S COG0457 FOG TPR repeat
MHMNNKED_02200 1.3e-83 ypiB S Belongs to the UPF0302 family
MHMNNKED_02201 1.9e-35 ypiF S Protein of unknown function (DUF2487)
MHMNNKED_02202 3.4e-78 qcrA C Menaquinol-cytochrome c reductase
MHMNNKED_02203 9.8e-118 petB C COG1290 Cytochrome b subunit of the bc complex
MHMNNKED_02204 3.4e-127 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MHMNNKED_02205 1.2e-71 ypjA S membrane
MHMNNKED_02206 4.4e-61 ypjB S sporulation protein
MHMNNKED_02207 1.9e-124 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MHMNNKED_02208 1.7e-81 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHMNNKED_02209 1.9e-70 yhfK GM Dihydrodipicolinate reductase, N-terminus
MHMNNKED_02210 2.7e-69 ykuD S L,D-transpeptidase catalytic domain
MHMNNKED_02211 1.3e-20
MHMNNKED_02212 8.1e-82 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHMNNKED_02213 1.7e-26 mutT 3.6.1.55 F NUDIX domain
MHMNNKED_02214 7.1e-24
MHMNNKED_02215 1.4e-19 V VanZ like family
MHMNNKED_02216 6.1e-17 L Phage integrase family
MHMNNKED_02217 5.6e-197 3.4.11.19 EQ Peptidase family S58
MHMNNKED_02218 1.5e-65 S DoxX
MHMNNKED_02219 5.6e-156 rbsB G Periplasmic binding protein domain
MHMNNKED_02220 2.1e-158 rbsC G COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components
MHMNNKED_02221 2.3e-44 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHMNNKED_02222 2.4e-41 betT M Belongs to the BCCT transporter (TC 2.A.15) family
MHMNNKED_02224 4.6e-18 fliT S bacterial-type flagellum organization
MHMNNKED_02225 4e-50 fliS N flagellar protein FliS
MHMNNKED_02226 2.4e-165 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHMNNKED_02227 4.6e-21 flaG N flagellar protein FlaG
MHMNNKED_02228 6.3e-60 tenI 2.5.1.3, 5.3.99.10 H Thiamine monophosphate synthase
MHMNNKED_02229 4.7e-15 thiS H ThiS family
MHMNNKED_02230 7.2e-125 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHMNNKED_02231 9.4e-141 moeB H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHMNNKED_02232 2.6e-153 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHMNNKED_02233 3.7e-57 nsrR K Transcriptional regulator
MHMNNKED_02234 1.3e-197 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHMNNKED_02235 3e-250 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHMNNKED_02236 1.8e-187 oppA1 E Bacterial extracellular solute-binding proteins, family 5 Middle
MHMNNKED_02237 9.2e-103 oppC EP binding-protein-dependent transport systems inner membrane component
MHMNNKED_02238 4.2e-114 oppB P Binding-protein-dependent transport system inner membrane component
MHMNNKED_02239 1.6e-139 oppF P Oligopeptide/dipeptide transporter, C-terminal region
MHMNNKED_02240 1.1e-139 oppD P Belongs to the ABC transporter superfamily
MHMNNKED_02241 1.7e-16 ytmB S Protein of unknown function (DUF2584)
MHMNNKED_02242 1.6e-137 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHMNNKED_02243 2.3e-110 ytlC P ABC transporter
MHMNNKED_02244 9.3e-99 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHMNNKED_02245 9.1e-38 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MHMNNKED_02246 6.3e-167 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHMNNKED_02247 8e-25
MHMNNKED_02248 3e-51 dps P Belongs to the Dps family
MHMNNKED_02249 1.5e-31 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MHMNNKED_02250 8.3e-102 adcA P Belongs to the bacterial solute-binding protein 9 family
MHMNNKED_02251 3.3e-182 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHMNNKED_02252 9e-142 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHMNNKED_02253 7.1e-78 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHMNNKED_02254 4.1e-184 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHMNNKED_02255 1.5e-115 menF 5.4.4.2 HQ Isochorismate synthase
MHMNNKED_02256 1.7e-131 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MHMNNKED_02257 1.1e-99 yphA
MHMNNKED_02258 6.3e-157 seaA S YIEGIA protein
MHMNNKED_02259 8.3e-27 ypzH
MHMNNKED_02261 4.7e-35 GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MHMNNKED_02262 3.5e-24
MHMNNKED_02263 6.6e-59 EGP Major facilitator Superfamily
MHMNNKED_02264 1.3e-139 KLT Protein kinase domain
MHMNNKED_02265 2.6e-158 EG of the drug metabolite transporter (DMT) superfamily
MHMNNKED_02266 2.5e-111 sapB S MgtC family
MHMNNKED_02267 5.6e-231 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHMNNKED_02268 8.8e-112 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MHMNNKED_02269 4.9e-07 S YlzJ-like protein
MHMNNKED_02270 2.6e-303 ftsK D Belongs to the FtsK SpoIIIE SftA family
MHMNNKED_02271 1.9e-126 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MHMNNKED_02272 6.4e-245 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MHMNNKED_02273 3.8e-153 yufP S Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_02274 6.7e-144 yufQ S Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_02275 1.2e-172 ymfF S Peptidase M16
MHMNNKED_02276 3.1e-189 ymfH S zinc protease
MHMNNKED_02277 5.1e-88 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHMNNKED_02278 3.5e-31 ymfJ S Protein of unknown function (DUF3243)
MHMNNKED_02279 3.1e-107 ymfK S Protein of unknown function (DUF3388)
MHMNNKED_02280 1.1e-68 ymfM S protein conserved in bacteria
MHMNNKED_02281 1.9e-82 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHMNNKED_02282 8.3e-163 cinA 3.5.1.42 S Belongs to the CinA family
MHMNNKED_02283 3.7e-266 suv3 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MHMNNKED_02284 1.5e-48 yaiI S Belongs to the UPF0178 family
MHMNNKED_02285 7.2e-65 J protein with SCP PR1 domains
MHMNNKED_02286 1.1e-231 pulA 3.2.1.41 CBM48,GH13 G Carbohydrate-binding module 48 (Isoamylase N-terminal domain)
MHMNNKED_02287 2.9e-284 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Alpha amylase, C-terminal all-beta domain
MHMNNKED_02288 4.5e-155 glgC 2.7.7.27 G MobA-like NTP transferase domain
MHMNNKED_02289 3.9e-148 glgD 2.7.7.27 G Nucleotidyl transferase
MHMNNKED_02290 2.5e-203 glgA 2.4.1.21 GT5 G Starch synthase catalytic domain
MHMNNKED_02291 0.0 glgP 2.4.1.1 GT35 G Carbohydrate phosphorylase
MHMNNKED_02293 2.9e-177 splB 4.1.99.14 L Radical SAM protein
MHMNNKED_02294 8e-26 yqhV S Protein of unknown function (DUF2619)
MHMNNKED_02295 1.4e-91 3.1.2.21 I Acyl-ACP thioesterase
MHMNNKED_02296 3.8e-07 2.7.1.24 H dephospho-CoA kinase activity
MHMNNKED_02298 6.6e-144 ybdG M Mechanosensitive ion channel
MHMNNKED_02300 2.9e-79 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHMNNKED_02301 1.8e-66 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHMNNKED_02302 7.7e-84 S Predicted nucleotidyltransferase
MHMNNKED_02303 5.4e-94 metQ P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
MHMNNKED_02304 4.5e-127 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHMNNKED_02305 1.8e-84 metI P COG2011 ABC-type metal ion transport system, permease component
MHMNNKED_02306 8.2e-209 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHMNNKED_02307 2e-284 sat 2.7.7.4 P the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MHMNNKED_02309 3.5e-145 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHMNNKED_02310 2.4e-27 yktA S Belongs to the UPF0223 family
MHMNNKED_02311 1.4e-81 yktB S Belongs to the UPF0637 family
MHMNNKED_02312 4.2e-107 suhB 3.1.3.25 G Inositol monophosphatase
MHMNNKED_02314 4.4e-306 typA T GTP-binding protein TypA
MHMNNKED_02315 1.6e-30 ylaH S YlaH-like protein
MHMNNKED_02316 7.9e-23 ylaI S protein conserved in bacteria
MHMNNKED_02317 3.2e-51 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHMNNKED_02318 4.2e-49 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHMNNKED_02319 1.9e-38 ylaN S Belongs to the UPF0358 family
MHMNNKED_02320 1.4e-132 ftsW D Belongs to the SEDS family
MHMNNKED_02321 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHMNNKED_02322 1.8e-104 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHMNNKED_02323 1.3e-123 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHMNNKED_02324 7.6e-133 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHMNNKED_02325 0.0 ctaD 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHMNNKED_02326 3.9e-92 cyoC 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHMNNKED_02327 3.1e-29 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHMNNKED_02328 8.5e-93 ctaG S cytochrome c oxidase
MHMNNKED_02329 4.6e-58 S Protein of unknown function (DUF420)
MHMNNKED_02330 4.6e-48 ylbA S YugN-like family
MHMNNKED_02331 4.2e-127 ylbC S protein with SCP PR1 domains
MHMNNKED_02332 2.2e-22 ylbD S Putative coat protein
MHMNNKED_02333 2.3e-18 ylbE S YlbE-like protein
MHMNNKED_02334 4.2e-53 ylbF S Belongs to the UPF0342 family
MHMNNKED_02335 2.3e-33 ylbG S UPF0298 protein
MHMNNKED_02336 4.7e-58
MHMNNKED_02337 7.4e-71 rsmD 2.1.1.171 L Methyltransferase
MHMNNKED_02338 1.8e-65 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHMNNKED_02339 2.1e-147 ylbJ S Sporulation integral membrane protein YlbJ
MHMNNKED_02340 2.3e-94 ylbK S esterase of the alpha-beta hydrolase superfamily
MHMNNKED_02341 1.7e-126 ylbL T Belongs to the peptidase S16 family
MHMNNKED_02342 5.1e-141 ylbM S Belongs to the UPF0348 family
MHMNNKED_02343 1.6e-51 yceD S metal-binding, possibly nucleic acid-binding protein
MHMNNKED_02344 8e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MHMNNKED_02345 6.8e-228 ato-1 2.8.3.18, 3.1.2.1 C Acetyl-CoA hydrolase/transferase N-terminal domain
MHMNNKED_02346 1.3e-90 K LytTr DNA-binding domain
MHMNNKED_02347 6.7e-147 E Belongs to the ABC transporter superfamily
MHMNNKED_02348 1.2e-140 oppD P Belongs to the ABC transporter superfamily
MHMNNKED_02349 3.9e-43 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHMNNKED_02350 6.2e-49 L Nuclease-related domain
MHMNNKED_02351 3.1e-96 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHMNNKED_02352 2.1e-35 S Protein of unknown function (DUF3892)
MHMNNKED_02353 9.5e-168 XK27_00915 C Luciferase-like monooxygenase
MHMNNKED_02354 6.9e-61 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHMNNKED_02355 2.9e-38 czrA K Transcriptional regulator
MHMNNKED_02356 2.4e-106 czcD P cation diffusion facilitator family transporter
MHMNNKED_02357 5e-122 livH E Belongs to the binding-protein-dependent transport system permease family
MHMNNKED_02358 1e-154 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MHMNNKED_02359 5e-147 lytH M Peptidase, M23
MHMNNKED_02360 1.6e-42 yutD S protein conserved in bacteria
MHMNNKED_02361 2.7e-44 yutE S Protein of unknown function DUF86
MHMNNKED_02362 2.8e-105 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHMNNKED_02363 4.5e-67 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MHMNNKED_02364 4.9e-97 yutH S Spore coat protein
MHMNNKED_02365 1.8e-136 gyaR 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHMNNKED_02366 4.8e-32 yutI O COG0694 Thioredoxin-like proteins and domains
MHMNNKED_02367 5.6e-40 yuzD S protein conserved in bacteria
MHMNNKED_02368 9.2e-238 iolA 1.2.1.18, 1.2.1.27 C Aldehyde dehydrogenase family
MHMNNKED_02369 1.5e-194 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHMNNKED_02370 3.6e-142 QT Regulator of polyketide synthase expression
MHMNNKED_02371 1.4e-190 gabP E Amino acid permease
MHMNNKED_02372 3.4e-94 devA 3.6.3.25 V Hemin ABC transporter ATP-binding protein
MHMNNKED_02373 1.5e-139 hrtB V FtsX-like permease family
MHMNNKED_02374 4e-116 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHMNNKED_02375 6.9e-58 yjbI S COG2346 Truncated hemoglobins
MHMNNKED_02376 1.2e-51 slt M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHMNNKED_02377 1.8e-54 yjbK S protein conserved in bacteria
MHMNNKED_02378 6e-90 yjbM 2.7.6.5 S GTP pyrophosphokinase
MHMNNKED_02379 1.6e-119 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHMNNKED_02380 2.4e-111 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHMNNKED_02381 8.2e-110 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHMNNKED_02382 7.5e-25 spoVK O ATPase, AAA family
MHMNNKED_02387 9.1e-18
MHMNNKED_02388 1.8e-28
MHMNNKED_02389 3.9e-111 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MHMNNKED_02391 3.2e-08
MHMNNKED_02392 2.3e-113 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MHMNNKED_02393 4.3e-93 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MHMNNKED_02394 7.9e-46 yitW S metal-sulfur cluster biosynthetic enzyme
MHMNNKED_02395 8.3e-16 yjzC S YjzC-like protein
MHMNNKED_02397 4.7e-84 yjaU I carboxylic ester hydrolase activity
MHMNNKED_02398 3.9e-11 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MHMNNKED_02399 1.4e-146 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHMNNKED_02400 5.2e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHMNNKED_02401 1.4e-132 atl 3.2.1.96, 3.5.1.28 GH73 G autolysin
MHMNNKED_02402 4.2e-115 3.5.1.28 M COG3103 SH3 domain protein
MHMNNKED_02403 1.8e-80 M Glycosyltransferase like family 2
MHMNNKED_02404 3.6e-36 tuaB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHMNNKED_02405 1.2e-173 potD E COG0687 Spermidine putrescine-binding periplasmic protein
MHMNNKED_02406 3.9e-113 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
MHMNNKED_02407 1.2e-117 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
MHMNNKED_02408 8.7e-180 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHMNNKED_02409 1.9e-79 puuR K Cupin domain
MHMNNKED_02410 6.1e-178 T PhoQ Sensor
MHMNNKED_02411 2.7e-107 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_02412 1.1e-10 ipi S Intracellular proteinase inhibitor
MHMNNKED_02413 4.3e-115 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHMNNKED_02414 1.1e-83 dedA 3.1.3.1 S SNARE associated Golgi protein
MHMNNKED_02415 3.5e-07 S YpzG-like protein
MHMNNKED_02416 3.3e-119 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHMNNKED_02417 4.6e-269 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHMNNKED_02418 1.2e-82 qoxC 1.10.3.12 C quinol oxidase, subunit
MHMNNKED_02419 8.2e-24 qoxD 1.10.3.12 C quinol oxidase, subunit
MHMNNKED_02420 3.1e-28 cidA S Effector of murein hydrolase LrgA
MHMNNKED_02421 2.3e-50 yxaC M effector of murein hydrolase
MHMNNKED_02422 1.6e-51 yceA S Belongs to the UPF0176 family
MHMNNKED_02423 8.5e-183 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MHMNNKED_02424 2.7e-51 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MHMNNKED_02425 3.6e-180 S Tripartite tricarboxylate transporter TctA family
MHMNNKED_02426 3.7e-20
MHMNNKED_02427 2e-61 K transcriptional
MHMNNKED_02428 2.3e-266 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHMNNKED_02429 1.2e-102 ytnM S membrane transporter protein
MHMNNKED_02430 6.6e-135 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MHMNNKED_02431 1.1e-35
MHMNNKED_02432 3.6e-115 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MHMNNKED_02433 5.2e-77 yfcE S Phosphoesterase
MHMNNKED_02434 5e-33
MHMNNKED_02435 5.6e-89 K LysR substrate binding domain
MHMNNKED_02436 4e-95 hutG 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHMNNKED_02437 9.4e-279 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHMNNKED_02438 2.4e-173 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MHMNNKED_02439 2.1e-172 S Nucleoside recognition
MHMNNKED_02440 8.1e-62 yrkC G Cupin domain
MHMNNKED_02441 1.8e-25 yqzD
MHMNNKED_02442 8.5e-41
MHMNNKED_02443 4.7e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHMNNKED_02444 4.1e-53 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHMNNKED_02445 4.7e-55 S Integral membrane protein DUF92
MHMNNKED_02447 2.7e-123 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MHMNNKED_02448 1.1e-68
MHMNNKED_02449 4.6e-221 spoVAF EG Bacillus/Clostridium GerA spore germination protein
MHMNNKED_02450 1.4e-17 yqgQ S Bacterial protein of unknown function (DUF910)
MHMNNKED_02451 2.2e-110 glk 2.7.1.2 G Glucokinase
MHMNNKED_02452 8.8e-209 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHMNNKED_02453 6e-155 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MHMNNKED_02454 1.2e-229 L COG3316 Transposase and inactivated derivatives
MHMNNKED_02455 1.4e-24 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHMNNKED_02456 1.8e-236 pbpC 3.4.16.4 M Penicillin-binding Protein
MHMNNKED_02457 6.2e-256 MA20_29420 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_02458 2.8e-88 S Uncharacterized protein conserved in bacteria (DUF2332)
MHMNNKED_02459 1.1e-33 yneR S Belongs to the HesB IscA family
MHMNNKED_02460 1.6e-62 ywiC S YwiC-like protein
MHMNNKED_02461 1.6e-170 ycgA S Membrane
MHMNNKED_02462 9.7e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHMNNKED_02463 6.1e-15 yvlD S PFAM Membrane protein of
MHMNNKED_02464 5.3e-44 F Nucleoside 2-deoxyribosyltransferase
MHMNNKED_02465 3e-168 mdxE G ABC transporter, substratebinding protein
MHMNNKED_02466 9.2e-181 malC P ABC transporter (Permease
MHMNNKED_02467 8.2e-122 malD P Binding-protein-dependent transport system inner membrane component
MHMNNKED_02468 1.9e-51 malA S maltodextrose utilization protein MalA
MHMNNKED_02469 1.9e-63 niaR S small molecule binding protein (contains 3H domain)
MHMNNKED_02470 1.5e-26 K helix_turn_helix multiple antibiotic resistance protein
MHMNNKED_02471 2.9e-45 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHMNNKED_02472 1.5e-59 S Pyridoxamine 5'-phosphate oxidase
MHMNNKED_02474 1.6e-69 M LysM domain
MHMNNKED_02475 2.5e-51 cph2 T Diguanylate cyclase
MHMNNKED_02476 5.5e-33 yocH M COG1388 FOG LysM repeat
MHMNNKED_02477 1.4e-241 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MHMNNKED_02478 1.6e-104 3.4.16.4 M Belongs to the peptidase S11 family
MHMNNKED_02479 1.4e-74 ypuA S Secreted protein
MHMNNKED_02480 6.4e-79
MHMNNKED_02481 7.1e-258 phnV P Binding-protein-dependent transport system inner membrane component
MHMNNKED_02482 2.2e-23 potA 3.6.3.30 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHMNNKED_02484 2.1e-76 L viral genome integration into host DNA
MHMNNKED_02485 1.3e-161 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHMNNKED_02486 3.6e-63 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHMNNKED_02487 1.2e-89 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MHMNNKED_02488 1.8e-57 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MHMNNKED_02491 1.2e-54 cvpA S membrane protein, required for colicin V production
MHMNNKED_02492 9.5e-234 polX L COG1796 DNA polymerase IV (family X)
MHMNNKED_02493 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHMNNKED_02494 7.6e-57 yshE S membrane
MHMNNKED_02495 1.6e-273 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_02496 2.9e-82 fadR K Transcriptional regulator
MHMNNKED_02497 4.9e-97 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHMNNKED_02498 3.4e-114 etfB C Electron transfer flavoprotein
MHMNNKED_02499 1.7e-150 etfA C Electron transfer flavoprotein
MHMNNKED_02500 2.2e-48 trxA O Belongs to the thioredoxin family
MHMNNKED_02501 1e-286 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHMNNKED_02502 4.1e-154 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHMNNKED_02503 5.3e-51 yslB S Protein of unknown function (DUF2507)
MHMNNKED_02504 7.6e-85 sdhC C succinate dehydrogenase
MHMNNKED_02505 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHMNNKED_02506 1.1e-141 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHMNNKED_02507 5.1e-49 ysmA S thioesterase
MHMNNKED_02510 4.2e-219 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHMNNKED_02511 5e-117 pfkB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MHMNNKED_02512 5.5e-47 acoC 2.3.1.12, 2.3.1.61 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MHMNNKED_02513 3.6e-217 L Transposase
MHMNNKED_02514 2.1e-104 K Bacterial regulatory helix-turn-helix protein, lysR family
MHMNNKED_02515 4.5e-09
MHMNNKED_02516 5.6e-178 ytoI K transcriptional regulator containing CBS domains
MHMNNKED_02517 5.6e-25 ytpI S YtpI-like protein
MHMNNKED_02518 2.2e-139 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MHMNNKED_02519 1.1e-18
MHMNNKED_02521 3.5e-306 L COG1112 Superfamily I DNA and RNA helicases and helicase subunits
MHMNNKED_02522 1.4e-44 2.8.3.12 I Coenzyme A transferase
MHMNNKED_02523 1.3e-115 2.8.3.12 I Coenzyme A transferase
MHMNNKED_02524 9e-99 catI 2.8.3.12 I acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHMNNKED_02525 7.2e-90 catJ 2.8.3.12 I PFAM Coenzyme A transferase
MHMNNKED_02527 4.2e-30 S DNA repair protein MmcB-like
MHMNNKED_02528 7.2e-46
MHMNNKED_02530 9.6e-99 bxlB G Binding-protein-dependent transport system inner membrane component
MHMNNKED_02531 1.3e-109 bxlC G Binding-protein-dependent transport system inner membrane component
MHMNNKED_02532 1.4e-120 bxlD G Bacterial extracellular solute-binding protein
MHMNNKED_02533 7.5e-118 fda 4.1.2.13 G Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis
MHMNNKED_02534 3.1e-156 metE2 2.1.1.14 E Methionine synthase
MHMNNKED_02535 5.6e-104 HJ RimK-like ATP-grasp domain
MHMNNKED_02536 1.1e-51 S DinB family
MHMNNKED_02537 5.5e-98 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHMNNKED_02538 1.7e-49 ybaK S Protein of unknown function (DUF2521)
MHMNNKED_02539 1e-24 S Small, acid-soluble spore proteins, alpha/beta type
MHMNNKED_02540 1.3e-27 yqgU
MHMNNKED_02541 2.2e-13 yqgW S Protein of unknown function (DUF2759)
MHMNNKED_02542 3.3e-28 yqgY S Protein of unknown function (DUF2626)
MHMNNKED_02543 1.7e-88 K Helix-turn-helix domain
MHMNNKED_02544 4.9e-293 expZ S ABC transporter
MHMNNKED_02545 4.4e-127 S Rifampin ADP-ribosyl transferase
MHMNNKED_02546 2e-21 S Phage capsid protein
MHMNNKED_02547 2e-07 M domain, Protein
MHMNNKED_02548 1.5e-37 yxeA S Protein of unknown function (DUF1093)
MHMNNKED_02549 2e-70 E Spore germination protein
MHMNNKED_02550 2e-113 gerKC S spore germination
MHMNNKED_02551 2.1e-169 gerKA EG Spore germination protein
MHMNNKED_02553 8.9e-271 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHMNNKED_02554 1.2e-21 sspD S small acid-soluble spore protein
MHMNNKED_02555 1.2e-162 ktrB P COG0168 Trk-type K transport systems, membrane components
MHMNNKED_02556 1.8e-115 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHMNNKED_02557 2.9e-64 L PFAM transposase IS204 IS1001 IS1096 IS1165 family protein
MHMNNKED_02558 7.7e-67 L Transposase
MHMNNKED_02559 1.2e-135 S Protein of unknown function C-terminus (DUF2399)
MHMNNKED_02560 1.3e-303 D Putative exonuclease SbcCD, C subunit
MHMNNKED_02561 1.1e-191 rny S Endoribonuclease that initiates mRNA decay
MHMNNKED_02562 2.2e-116 ymdB S protein conserved in bacteria
MHMNNKED_02563 1.9e-37 spoVS S Stage V sporulation protein S
MHMNNKED_02564 1.2e-49 S Domain of unknown function (DU1801)
MHMNNKED_02565 2.9e-253 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHMNNKED_02566 3.9e-43 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MHMNNKED_02567 3.5e-71 ypbG S Calcineurin-like phosphoesterase superfamily domain
MHMNNKED_02568 1.4e-69 cotE S Spore coat protein
MHMNNKED_02569 1.9e-220 sdcS P Sodium:sulfate symporter transmembrane region
MHMNNKED_02570 1.4e-244 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHMNNKED_02571 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHMNNKED_02572 1.1e-262 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHMNNKED_02574 6.9e-63 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHMNNKED_02576 1.7e-137 S Uncharacterized protein conserved in bacteria C-term(DUF2220)
MHMNNKED_02577 1.9e-206
MHMNNKED_02578 9.4e-114
MHMNNKED_02579 0.0 D nuclear chromosome segregation
MHMNNKED_02580 1.2e-44 P Nitrate nitrite transporter
MHMNNKED_02581 2e-102 narI 1.7.5.1 C nitrate reductase, gamma subunit
MHMNNKED_02582 1e-65 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MHMNNKED_02583 1.2e-288 narH 1.7.5.1 C Nitrate reductase, beta
MHMNNKED_02584 2.1e-117 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHMNNKED_02585 4.1e-82 S Nuclease-related domain
MHMNNKED_02586 7e-73 S EcsC protein family
MHMNNKED_02587 2.2e-57 uspA T Belongs to the universal stress protein A family
MHMNNKED_02588 3.3e-155 ald 1.4.1.1 C Alanine dehydrogenase/PNT, N-terminal domain
MHMNNKED_02589 7.1e-147 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MHMNNKED_02590 6.8e-145 3.1.1.81 S Metallo-beta-lactamase superfamily
MHMNNKED_02591 5.2e-133 corA P Mediates influx of magnesium ions
MHMNNKED_02592 7.9e-69 1.4.3.5 S Pyridoxamine 5'phosphate oxidase-like, FMN-binding
MHMNNKED_02594 8.4e-08 VPA1573 J acetyltransferase
MHMNNKED_02595 3.4e-88 P Copper resistance protein D
MHMNNKED_02596 9.5e-29 copC S CopC domain
MHMNNKED_02597 5.7e-59 J COG0457 FOG TPR repeat
MHMNNKED_02598 2e-18 K Transcriptional
MHMNNKED_02599 3.5e-21
MHMNNKED_02600 1.3e-99 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHMNNKED_02601 1.1e-114 rarD S -transporter
MHMNNKED_02602 8.3e-244 S PFAM Uncharacterised protein family UPF0236
MHMNNKED_02603 1.2e-50 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHMNNKED_02605 1.5e-99 S membrane
MHMNNKED_02606 2.8e-59 M1-344 S Putative vitamin uptake transporter
MHMNNKED_02607 9.1e-100 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHMNNKED_02608 5.5e-37 V ABC transporter, ATP-binding protein
MHMNNKED_02609 1e-75 mutE S ABC-2 family transporter protein
MHMNNKED_02610 2.6e-63 S ABC-2 family transporter protein
MHMNNKED_02611 4.8e-67 potA3 V ABC transporter
MHMNNKED_02612 2.7e-49 S ABC-2 family transporter protein
MHMNNKED_02613 9.2e-82 T PhoP family transcriptional regulator
MHMNNKED_02614 2.5e-71 T His Kinase A (phosphoacceptor) domain
MHMNNKED_02615 5e-14 S Protein of unknown function (DUF3307)
MHMNNKED_02616 8.2e-276 ydgH S drug exporters of the RND superfamily
MHMNNKED_02617 1.6e-46 K helix_turn_helix multiple antibiotic resistance protein
MHMNNKED_02618 4e-144 kinE 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHMNNKED_02621 2.5e-33
MHMNNKED_02622 3.1e-20 K TfoX N-terminal domain
MHMNNKED_02623 5e-173 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHMNNKED_02624 7.6e-154 ylbA 3.5.3.26 S protein, possibly involved in glyoxylate utilization
MHMNNKED_02625 7.2e-197 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHMNNKED_02626 1.6e-199 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHMNNKED_02627 0.0 sucD 6.2.1.5 C COG0074 Succinyl-CoA synthetase, alpha subunit
MHMNNKED_02628 7.9e-246 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
MHMNNKED_02629 4.7e-140 S Protein of unknown function (DUF2877)
MHMNNKED_02630 1.1e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MHMNNKED_02631 2.8e-142 L Transposase
MHMNNKED_02632 1.6e-86 L Transposase
MHMNNKED_02634 3.1e-14
MHMNNKED_02635 1.7e-24 narK P COG2223 Nitrate nitrite transporter
MHMNNKED_02636 1.2e-151 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHMNNKED_02637 1.5e-130 H Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor
MHMNNKED_02638 1.8e-30 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHMNNKED_02639 1.4e-55 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MHMNNKED_02640 1.6e-68 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MHMNNKED_02641 7.9e-72 modB P COG4149 ABC-type molybdate transport system, permease component
MHMNNKED_02642 1.1e-118 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHMNNKED_02643 1.4e-146 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MHMNNKED_02644 2.8e-79 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MHMNNKED_02645 6.5e-152 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHMNNKED_02646 8.2e-140 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHMNNKED_02647 1.3e-17 S Protein of unknown function (DUF3992)
MHMNNKED_02650 8.7e-203 atoE I Short chain fatty acid transporter
MHMNNKED_02651 1.5e-95 yijE EG EamA-like transporter family
MHMNNKED_02652 2.5e-114 EG EamA-like transporter family
MHMNNKED_02654 2.5e-28 S Ketosteroid isomerase-related protein
MHMNNKED_02657 1.5e-07
MHMNNKED_02658 1.9e-161 megL 4.4.1.1, 4.4.1.11, 4.4.1.8 E methionine gamma-lyase
MHMNNKED_02659 3.3e-55 S Protein of unknown function (DUF1284)
MHMNNKED_02660 3.7e-22
MHMNNKED_02661 4.5e-09 S YpzI-like protein
MHMNNKED_02662 5.7e-10 S Fur-regulated basic protein A
MHMNNKED_02663 5.3e-21
MHMNNKED_02664 6.2e-66 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MHMNNKED_02665 3.3e-185 E Hippurate hydrolase
MHMNNKED_02666 1.4e-128 ydjI S virion core protein (lumpy skin disease virus)
MHMNNKED_02667 2.6e-58 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MHMNNKED_02668 1.6e-127 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHMNNKED_02669 3.5e-54 pspA KT Phage shock protein A
MHMNNKED_02670 8.6e-100 M COG2834 Outer membrane lipoprotein-sorting protein
MHMNNKED_02671 1.3e-07
MHMNNKED_02672 1.5e-113 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MHMNNKED_02673 2.6e-72 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MHMNNKED_02674 2.6e-182 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MHMNNKED_02675 1.7e-30 S DNA alkylation repair protein
MHMNNKED_02676 2e-42 yozR S COG0071 Molecular chaperone (small heat shock protein)
MHMNNKED_02677 5.6e-66 6.1.1.5 J Acetyltransferase (GNAT) domain
MHMNNKED_02678 1.4e-165 mcrB V AAA domain (dynein-related subfamily)
MHMNNKED_02679 5.8e-29 S Family of unknown function (DUF5316)
MHMNNKED_02680 7.8e-91
MHMNNKED_02681 1.1e-121 V ATPases associated with a variety of cellular activities
MHMNNKED_02682 2.4e-253 ywjA V abc transporter atp-binding protein
MHMNNKED_02683 7.7e-104 M Glycosyl transferase family 8
MHMNNKED_02684 2.8e-195 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MHMNNKED_02685 1.1e-57 K LysR substrate binding domain
MHMNNKED_02686 3.5e-180 gabT 2.6.1.19 E Aminotransferase class-III
MHMNNKED_02687 3.8e-140 E Sodium:solute symporter family
MHMNNKED_02688 6.4e-18 G Glycerol-3-phosphate ABC transporter substrate-binding protein
MHMNNKED_02689 2e-49 G Binding-protein-dependent transport system inner membrane component
MHMNNKED_02690 1.6e-51 G Binding-protein-dependent transport system inner membrane component
MHMNNKED_02691 1.9e-137 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MHMNNKED_02692 2.1e-38 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHMNNKED_02693 1.5e-215 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHMNNKED_02694 8e-35 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHMNNKED_02695 3.9e-262 gmuD 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHMNNKED_02696 3.9e-260 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MHMNNKED_02697 3e-136 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHMNNKED_02698 6e-108 est 3.1.1.1 S Carboxylesterase
MHMNNKED_02699 1.3e-21 secG U Preprotein translocase subunit SecG
MHMNNKED_02700 4.9e-08 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MHMNNKED_02701 3e-121 cobD 2.6.1.9, 4.1.1.81 E COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
MHMNNKED_02702 2.1e-47 cobU 2.7.1.156, 2.7.7.62 H COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase
MHMNNKED_02703 3.6e-137 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHMNNKED_02704 1.1e-116 yxeN E Binding-protein-dependent transport system inner membrane component
MHMNNKED_02705 1.1e-125 ytmL E Binding-protein-dependent transport system inner membrane component
MHMNNKED_02706 3.7e-271 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHMNNKED_02707 5.6e-72 S RloB-like protein
MHMNNKED_02708 3.6e-169 S AAA domain, putative AbiEii toxin, Type IV TA system
MHMNNKED_02709 1.3e-43 yneH 1.20.4.1 P ArsC family
MHMNNKED_02710 2.2e-55 K Bacterial regulatory proteins, tetR family
MHMNNKED_02711 4.9e-61 usp M protein conserved in bacteria
MHMNNKED_02712 1.6e-81 ybaP G PFAM GumN family protein
MHMNNKED_02713 1.8e-239 bgaA 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MHMNNKED_02714 9.5e-42 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHMNNKED_02715 4.5e-39 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHMNNKED_02716 1e-95 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHMNNKED_02717 8.1e-54 zur P Belongs to the Fur family
MHMNNKED_02718 2.6e-33 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MHMNNKED_02719 3e-127 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHMNNKED_02720 7.3e-183 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHMNNKED_02721 3.3e-155 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHMNNKED_02722 3.3e-85 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHMNNKED_02723 1.7e-133 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MHMNNKED_02724 1.7e-38 ymxH S YlmC YmxH family
MHMNNKED_02725 1.1e-75 pepR S Insulinase (Peptidase family M16)
MHMNNKED_02726 3.1e-111 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHMNNKED_02727 4e-82 sapB S MgtC SapB transporter
MHMNNKED_02728 1.4e-76 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHMNNKED_02729 4.5e-74 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHMNNKED_02730 6.1e-247 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHMNNKED_02731 2e-112 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHMNNKED_02732 1.5e-07 ypgQ S phosphohydrolase
MHMNNKED_02734 2.1e-26 T SpoVT / AbrB like domain
MHMNNKED_02735 4.9e-45 doc S Fic/DOC family
MHMNNKED_02737 5.1e-145 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHMNNKED_02738 1e-273 5.99.1.2 T diguanylate cyclase
MHMNNKED_02739 1e-270 dapE 3.5.1.16, 3.5.1.18 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHMNNKED_02740 5.5e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
MHMNNKED_02741 1e-235 yfkN 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MHMNNKED_02742 2.2e-88 T PhoQ Sensor
MHMNNKED_02743 2.8e-60 S ABC-2 family transporter protein
MHMNNKED_02744 5.1e-125 V abc transporter atp-binding protein
MHMNNKED_02745 1.6e-94 T Xre family transcriptional regulator
MHMNNKED_02746 1.7e-57
MHMNNKED_02747 1.6e-13 1.9.3.1 O COG3278 Cbb3-type cytochrome oxidase, subunit 1
MHMNNKED_02748 6.7e-35 bigR K Bacterial regulatory protein, arsR family
MHMNNKED_02749 7.3e-13
MHMNNKED_02750 1.1e-219 ma_1747 S ABC transporter
MHMNNKED_02751 2.4e-29 yqkA1 S GrpB protein
MHMNNKED_02752 3.9e-47 2.3.1.128 K PFAM GCN5-related N-acetyltransferase
MHMNNKED_02753 3e-52 3.6.1.55 F NUDIX domain
MHMNNKED_02754 8.9e-145 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHMNNKED_02755 5e-43 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MHMNNKED_02756 1e-14
MHMNNKED_02757 7.2e-32 rpmE J Ribosomal protein L31
MHMNNKED_02758 5e-219 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHMNNKED_02760 5.5e-11 S Belongs to the WXG100 family
MHMNNKED_02761 1.6e-202 M1-161 T HD domain
MHMNNKED_02762 1.6e-81 comEB 3.5.4.12 F MafB19-like deaminase
MHMNNKED_02763 3.1e-57 S DinB family
MHMNNKED_02764 1.8e-78 C Nitroreductase family
MHMNNKED_02765 4.8e-100 ykoY P Integral membrane protein TerC family
MHMNNKED_02766 2e-90 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHMNNKED_02768 8.1e-13
MHMNNKED_02769 2.4e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHMNNKED_02770 2e-49 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHMNNKED_02771 1.1e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHMNNKED_02772 5.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
MHMNNKED_02773 2.6e-62 atpI S ATP synthase I chain
MHMNNKED_02774 2.2e-60 vpr O Belongs to the peptidase S8 family
MHMNNKED_02775 1.4e-84 naiP EGP Major facilitator Superfamily
MHMNNKED_02776 9.6e-212 L Transposase zinc-binding domain
MHMNNKED_02777 2e-23
MHMNNKED_02779 2.3e-91 K Helix-turn-helix domain, rpiR family
MHMNNKED_02780 3.2e-228 2.7.1.199, 2.7.1.208 G phosphotransferase system
MHMNNKED_02781 4e-232 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHMNNKED_02782 5.8e-59 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHMNNKED_02783 1.3e-86 L Phage integrase, N-terminal SAM-like domain
MHMNNKED_02785 3.3e-182 argH2 4.3.2.1 E argininosuccinate lyase
MHMNNKED_02786 2.5e-250 phnV P Binding-protein-dependent transport system inner membrane component
MHMNNKED_02787 9.7e-144 potA 3.6.3.30 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHMNNKED_02788 1.9e-150 P Bacterial extracellular solute-binding protein
MHMNNKED_02790 3.5e-311 mca M NPCBM-associated, NEW3 domain of alpha-galactosidase
MHMNNKED_02791 1.1e-143 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
MHMNNKED_02792 2.5e-166 lysDH 1.4.1.18 E Saccharopine dehydrogenase C-terminal domain
MHMNNKED_02793 9.5e-147 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHMNNKED_02794 1.9e-72 thiT S Proton-coupled thiamine transporter YuaJ
MHMNNKED_02795 1.8e-206 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
MHMNNKED_02796 7.5e-13 hspX O COG0071 Molecular chaperone (small heat shock protein)
MHMNNKED_02798 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHMNNKED_02799 7.1e-134 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MHMNNKED_02801 2.2e-11 sspN S Small acid-soluble spore protein N family
MHMNNKED_02802 5.2e-15 tlp S Belongs to the Tlp family
MHMNNKED_02803 2.1e-276 spoVK O stage V sporulation protein K
MHMNNKED_02804 9.2e-58 yneP S thioesterase
MHMNNKED_02805 7.7e-41 yneQ
MHMNNKED_02806 5e-27 ytkA S YtkA-like
MHMNNKED_02807 1e-71 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHMNNKED_02809 2.1e-128 spoIIP M stage II sporulation protein P
MHMNNKED_02810 5e-126 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHMNNKED_02811 6.3e-12 XAC3035 O Glutaredoxin-like domain (DUF836)
MHMNNKED_02812 3.3e-125 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHMNNKED_02813 1.4e-160 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHMNNKED_02814 1.6e-21 K MerR HTH family regulatory protein
MHMNNKED_02816 8.6e-28
MHMNNKED_02817 3.5e-23 L Initiator Replication protein
MHMNNKED_02818 5.5e-29
MHMNNKED_02819 5.8e-163 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHMNNKED_02820 1.7e-183 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHMNNKED_02821 1.6e-240 L Transposase domain (DUF772)
MHMNNKED_02822 2e-173 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
MHMNNKED_02823 2.9e-16
MHMNNKED_02824 6.1e-151 S Protein of unknown function
MHMNNKED_02825 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHMNNKED_02826 1.6e-159 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHMNNKED_02827 1.4e-96 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHMNNKED_02828 2.4e-22 sspI S Belongs to the SspI family
MHMNNKED_02829 8.2e-149 M Glycosyl Transferase
MHMNNKED_02830 7.7e-173 ysdC G COG1363 Cellulase M and related proteins
MHMNNKED_02831 4.8e-57 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
MHMNNKED_02832 7.3e-55 ysdB S Sigma-w pathway protein YsdB
MHMNNKED_02833 6.4e-70 S SNARE associated Golgi protein
MHMNNKED_02834 4.2e-17 ysdA S Protein of unknown function (DUF1294)
MHMNNKED_02835 2.3e-45 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MHMNNKED_02837 2.3e-24 S Protease prsW family
MHMNNKED_02838 1.6e-33 L Restriction endonuclease BamHI
MHMNNKED_02840 1.6e-67 lpg2 2.4.1.337 GT4 M Glycosyl transferases group 1
MHMNNKED_02841 3.5e-22 S Hexapeptide repeat of succinyl-transferase
MHMNNKED_02843 6.7e-202 mrdA 3.4.16.4 M COG0768 Cell division protein FtsI penicillin-binding protein 2
MHMNNKED_02844 1.6e-245 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHMNNKED_02845 3.7e-39 yueI S Protein of unknown function (DUF1694)
MHMNNKED_02846 3.8e-34 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHMNNKED_02847 7.2e-19 P ABC transporter
MHMNNKED_02848 7.4e-115 U Binding-protein-dependent transport system inner membrane component
MHMNNKED_02849 1.3e-31 yeaO S Protein of unknown function, DUF488
MHMNNKED_02850 5.3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHMNNKED_02851 1.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHMNNKED_02852 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHMNNKED_02854 1.9e-14
MHMNNKED_02855 9.3e-19 K Helix-turn-helix XRE-family like proteins
MHMNNKED_02856 9.3e-76 tnpR1 L Resolvase, N terminal domain
MHMNNKED_02857 1e-10 sca1 D Phage tail tape measure protein
MHMNNKED_02858 5.6e-66 sca1 D Phage tail tape measure protein
MHMNNKED_02862 9.5e-59 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHMNNKED_02863 1.5e-156 yaaN P Belongs to the TelA family
MHMNNKED_02864 1.2e-16 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MHMNNKED_02865 2.8e-72 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S haloacid dehalogenase-like hydrolase
MHMNNKED_02866 2.8e-130 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHMNNKED_02867 2.3e-83 K helix_turn_helix, arabinose operon control protein
MHMNNKED_02868 1.2e-64 V VanZ like family
MHMNNKED_02869 1.8e-99 V VanZ like family
MHMNNKED_02870 9.8e-56 K Transcriptional regulator PadR-like family
MHMNNKED_02871 6.2e-73 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHMNNKED_02872 2.5e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MHMNNKED_02873 6e-31 cccB C Cytochrome c
MHMNNKED_02874 1.3e-72 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHMNNKED_02875 6e-138 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MHMNNKED_02876 5.3e-75 bioY S Biotin biosynthesis protein
MHMNNKED_02877 1.9e-149 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHMNNKED_02878 3.3e-74 noeI M Putative rRNA methylase
MHMNNKED_02879 6.6e-160 yhcC S Fe-S oxidoreductase
MHMNNKED_02880 2.1e-23 ytzC S Protein of unknown function (DUF2524)
MHMNNKED_02881 4.5e-155 MA20_40060 1.3.8.6, 1.3.8.7 I Acyl-CoA dehydrogenase, middle domain
MHMNNKED_02882 2.2e-82 MA20_40065 1.3.8.7, 2.3.1.9 I Acyl-CoA dehydrogenase, C-terminal domain
MHMNNKED_02883 2.1e-111 5.3.3.18 I Enoyl-CoA hydratase/isomerase
MHMNNKED_02884 6.5e-30 tehB 2.1.1.265 Q methyltransferase
MHMNNKED_02885 1.7e-88 argD 2.6.1.11, 2.6.1.17, 2.6.1.18, 2.6.1.36, 2.6.1.55, 2.6.1.62, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHMNNKED_02886 3.6e-09 yydH S Psort location CytoplasmicMembrane, score 10.00
MHMNNKED_02887 1.5e-52 IQ Enoyl-(Acyl carrier protein) reductase
MHMNNKED_02888 5.3e-95 natA S ABC transporter, ATP-binding protein
MHMNNKED_02889 4.3e-63 sipS 3.4.21.89 U Signal peptidase, peptidase S26
MHMNNKED_02890 1e-63 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHMNNKED_02891 3.1e-72 tag 3.2.2.20 L Methyladenine glycosylase
MHMNNKED_02892 5.2e-136 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHMNNKED_02893 2e-304 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
MHMNNKED_02894 4.4e-241 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHMNNKED_02895 2.4e-34 S Thioesterase-like superfamily
MHMNNKED_02896 5.5e-149 yfmJ S N-terminal domain of oxidoreductase
MHMNNKED_02897 7.4e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MHMNNKED_02898 6.9e-125 haeIIIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
MHMNNKED_02899 1.6e-78 L HaeIII restriction endonuclease
MHMNNKED_02900 2.4e-54 S Protein of unknown function DUF262
MHMNNKED_02903 9e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHMNNKED_02904 2e-144 yycI S YycH protein
MHMNNKED_02905 2e-61 yycH S Two-component system yycF yycG regulatory protein
MHMNNKED_02906 3.1e-242 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHMNNKED_02907 1.4e-57 S Staygreen protein
MHMNNKED_02910 2.4e-65 S ABC-2 family transporter protein
MHMNNKED_02911 1.5e-31 V abc transporter atp-binding protein
MHMNNKED_02912 1.3e-28 K Sigma-70, region 4
MHMNNKED_02914 7.4e-21 XK27_00085 K transcriptional
MHMNNKED_02915 1.4e-25
MHMNNKED_02916 3.9e-25
MHMNNKED_02917 1.3e-10 G Extracellular solute-binding protein
MHMNNKED_02918 1.9e-11 cps3F
MHMNNKED_02919 2.4e-272 M Sulfatase
MHMNNKED_02920 2.6e-43
MHMNNKED_02921 4.6e-105 L COG1484 DNA replication protein
MHMNNKED_02922 6.1e-210 L COG4584 Transposase and inactivated derivatives
MHMNNKED_02923 5.6e-239 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MHMNNKED_02924 2.1e-08
MHMNNKED_02925 5.1e-64 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHMNNKED_02926 5.1e-30 cspD K Cold-shock protein
MHMNNKED_02927 6.3e-15 ypeQ S Zinc-finger
MHMNNKED_02928 2e-24 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MHMNNKED_02929 1.2e-45 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHMNNKED_02930 1.7e-166 accC2 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MHMNNKED_02931 9e-09 yngHB 2.1.3.1, 6.4.1.1 C Biotin carboxyl carrier protein
MHMNNKED_02932 1.1e-241 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHMNNKED_02933 9.3e-68 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHMNNKED_02934 6.5e-168 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHMNNKED_02935 2.8e-70 mraZ K Belongs to the MraZ family
MHMNNKED_02936 3.2e-135 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHMNNKED_02938 2.4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
MHMNNKED_02939 5.3e-311 ftsI 3.4.16.4 M stage V sporulation protein D
MHMNNKED_02940 2.3e-191 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHMNNKED_02941 5.1e-144 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHMNNKED_02942 9.5e-197 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHMNNKED_02943 9.1e-182 spoVE D Belongs to the SEDS family
MHMNNKED_02944 4.9e-231 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHMNNKED_02945 2.6e-29 ptsH G phosphocarrier protein HPr
MHMNNKED_02946 2.8e-268 ptsG 2.7.1.193, 2.7.1.199 G phosphotransferase system
MHMNNKED_02947 8.3e-190 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MHMNNKED_02948 2e-203 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHMNNKED_02949 4.2e-132 xerD L recombinase XerD
MHMNNKED_02950 6.6e-26 S Protein of unknown function (DUF4227)
MHMNNKED_02951 5.2e-73 fur P Belongs to the Fur family
MHMNNKED_02952 2.4e-86 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHMNNKED_02953 5.7e-166 yqxK 3.6.4.12 L DNA helicase
MHMNNKED_02954 1.6e-66 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MHMNNKED_02956 4e-59 T Response regulator containing a CheY-like receiver domain and an HD-GYP domain
MHMNNKED_02958 6.8e-138 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHMNNKED_02959 1.4e-128 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHMNNKED_02960 8.1e-63 yycI S protein conserved in bacteria
MHMNNKED_02961 2.6e-87 yycH S protein conserved in bacteria
MHMNNKED_02962 2.9e-233 vicK 2.7.13.3 T Histidine kinase
MHMNNKED_02963 1.1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHMNNKED_02964 8.7e-158 C 4Fe-4S single cluster domain
MHMNNKED_02965 4.7e-41 4.1.1.36, 6.3.2.5 H Flavoprotein
MHMNNKED_02966 1e-146 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MHMNNKED_02967 3.6e-45 ypmB S protein conserved in bacteria
MHMNNKED_02968 9.6e-161 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MHMNNKED_02969 4.6e-225 asnS 6.1.1.22 J asparaginyl-tRNA
MHMNNKED_02970 2.9e-34 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHMNNKED_02971 2.6e-236 L Transposase
MHMNNKED_02972 9.2e-161 ald 1.4.1.1 E Alanine dehydrogenase/PNT, N-terminal domain
MHMNNKED_02973 6.3e-110 yukF QT PucR C-terminal helix-turn-helix domain
MHMNNKED_02974 2.4e-121 S membrane
MHMNNKED_02975 6.9e-150 S Putative nucleotide-binding of sugar-metabolising enzyme
MHMNNKED_02976 2.5e-143 ywaD 3.4.11.10, 3.4.11.6 S Peptidase family M28
MHMNNKED_02977 2.1e-96 isp O Belongs to the peptidase S8 family
MHMNNKED_02978 1.1e-18 G Belongs to the glycosyl hydrolase 43 family
MHMNNKED_02979 6.5e-47 V Mate efflux family protein
MHMNNKED_02980 2.7e-20 uidA G Belongs to the glycosyl hydrolase 2 family
MHMNNKED_02981 1.1e-60 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
MHMNNKED_02982 1.1e-108 dpnB 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
MHMNNKED_02983 2.2e-98 L Belongs to the N(4) N(6)-methyltransferase family
MHMNNKED_02984 1.6e-94 L PFAM transposase, IS4 family protein
MHMNNKED_02985 2.5e-104 3.4.22.70 M sortase family
MHMNNKED_02986 3.8e-94 3.1.1.3 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHMNNKED_02987 4.1e-227
MHMNNKED_02988 7.1e-16 rsbT 2.7.11.1 T Histidine kinase-like ATPase domain
MHMNNKED_02989 1e-138 kinE 2.7.13.3 T STAS domain
MHMNNKED_02990 1.6e-93 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHMNNKED_02991 2.1e-218 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHMNNKED_02992 9.7e-137 G PUCC protein
MHMNNKED_02993 9.4e-99 traC L Domain of unknown function (DUF1738)
MHMNNKED_02998 3.9e-248 5.99.1.2 G DNA topoisomerase III
MHMNNKED_03001 3.8e-08
MHMNNKED_03003 1.4e-43 radC L RadC-like JAB domain
MHMNNKED_03008 6.6e-31
MHMNNKED_03011 2.4e-60 V Restriction endonuclease
MHMNNKED_03012 4.4e-80 5.99.1.2 G DNA topoisomerase III
MHMNNKED_03015 6.3e-129 S CAAX protease self-immunity
MHMNNKED_03016 1.9e-86 S Bacterial PH domain
MHMNNKED_03017 8.7e-25 wgaB M Psort location Cytoplasmic, score 8.87
MHMNNKED_03018 3.7e-51 S Polysaccharide biosynthesis protein
MHMNNKED_03019 2.1e-18 S Glycosyltransferase like family 2
MHMNNKED_03020 4.4e-41 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MHMNNKED_03021 6.2e-20 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MHMNNKED_03022 6.8e-67 glcR K DeoR C terminal sensor domain
MHMNNKED_03023 1.4e-46 cof S Sucrose-6F-phosphate phosphohydrolase
MHMNNKED_03025 3.5e-71
MHMNNKED_03026 0.0 pflB 2.3.1.54 C formate acetyltransferase
MHMNNKED_03027 5.1e-120 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHMNNKED_03028 8e-74 S Protein of unknown function (DUF3298)
MHMNNKED_03030 8.7e-16 yisR K helix_turn_helix, arabinose operon control protein
MHMNNKED_03031 1.3e-26 yisR K helix_turn_helix, arabinose operon control protein
MHMNNKED_03032 7.8e-79 yisR K helix_turn_helix, arabinose operon control protein
MHMNNKED_03033 1.9e-263 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MHMNNKED_03034 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHMNNKED_03035 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHMNNKED_03036 1.8e-56 msbA2 3.6.3.44 V ABC transporter
MHMNNKED_03038 2.4e-24 O Subtilase family
MHMNNKED_03039 3.7e-234 asnB 6.3.5.4 E Asparagine synthase
MHMNNKED_03041 3.9e-125 xylR GK ROK family
MHMNNKED_03042 8.6e-51 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHMNNKED_03043 5.8e-56 S DinB family
MHMNNKED_03044 7.6e-74 L Tn3 transposase DDE domain
MHMNNKED_03045 7.8e-212 L PFAM Transposase, IS4-like
MHMNNKED_03046 1.1e-46 F ATP-grasp domain
MHMNNKED_03047 7.7e-07 2.3.1.128 K acetyltransferase
MHMNNKED_03048 2.3e-164 vioA 2.6.1.33 E Belongs to the DegT DnrJ EryC1 family
MHMNNKED_03049 8.9e-145 U protein localization to endoplasmic reticulum
MHMNNKED_03050 1.3e-63 coaW 2.7.1.33 H Pantothenate kinase
MHMNNKED_03051 1.2e-55 yneK S Protein of unknown function (DUF2621)
MHMNNKED_03052 5.4e-38 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MHMNNKED_03053 2.6e-97 ccdA O cytochrome c biogenesis protein
MHMNNKED_03054 2e-234 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHMNNKED_03055 1.8e-248 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHMNNKED_03056 1.3e-26 yneF S UPF0154 protein
MHMNNKED_03057 2e-45 yneE S Sporulation inhibitor of replication protein sirA
MHMNNKED_03059 6.3e-24 ynzC S UPF0291 protein
MHMNNKED_03060 1e-82 yneB L resolvase
MHMNNKED_03062 5.7e-96 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHMNNKED_03064 7e-29 M NLP P60 protein
MHMNNKED_03065 3.1e-31 L RePlication protein
MHMNNKED_03066 2.8e-29 L RePlication protein
MHMNNKED_03067 1.3e-07 L Eco57I restriction-modification methylase
MHMNNKED_03068 3e-115 yugO P COG1226 Kef-type K transport systems
MHMNNKED_03069 1.1e-229 pgi 5.3.1.9 G Belongs to the GPI family
MHMNNKED_03070 3.8e-194 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHMNNKED_03071 3.9e-26 yuzA S Domain of unknown function (DUF378)
MHMNNKED_03072 9.7e-56 ygzB S UPF0295 protein
MHMNNKED_03073 2.4e-80 perR P Belongs to the Fur family
MHMNNKED_03074 7.6e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
MHMNNKED_03075 7.3e-78 yrrM 2.1.1.104 S O-methyltransferase
MHMNNKED_03076 5.8e-123 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHMNNKED_03077 1.6e-18 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHMNNKED_03079 2.4e-42 S DNA alkylation repair protein
MHMNNKED_03080 1.8e-86 yozR S COG0071 Molecular chaperone (small heat shock protein)
MHMNNKED_03081 9.5e-106 6.1.1.5 J Acetyltransferase (GNAT) domain
MHMNNKED_03082 7.7e-58 ytxK 2.1.1.72 L DNA methylase
MHMNNKED_03083 2.6e-190 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHMNNKED_03084 5.3e-60 S Domain of unknown function (DUF1837)
MHMNNKED_03085 3.4e-21
MHMNNKED_03086 8.5e-15 2.7.1.11 G alpha-ribazole phosphatase activity
MHMNNKED_03087 4.1e-40
MHMNNKED_03090 4.5e-21 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHMNNKED_03091 3e-105 S Sucrose-6F-phosphate phosphohydrolase
MHMNNKED_03092 1.6e-97 yvaK 3.1.1.1 S Alpha/beta hydrolase family
MHMNNKED_03093 3.6e-08 draG 3.2.2.24 O PFAM ADP-ribosylation Crystallin J1
MHMNNKED_03094 1.1e-49 yabJ 3.5.99.10 J Endoribonuclease L-PSP
MHMNNKED_03095 1.6e-181 E Sodium:solute symporter family
MHMNNKED_03096 4.6e-207 1.14.14.28 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHMNNKED_03097 1.1e-56 osmC O OsmC-like protein
MHMNNKED_03098 9.4e-93 M1-591 L TatD related DNase
MHMNNKED_03099 8.4e-159 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHMNNKED_03100 5.2e-165 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHMNNKED_03102 2.7e-54 M Domain of unknown function (DUF4349)
MHMNNKED_03103 2e-76 S membrane transporter protein
MHMNNKED_03104 1.8e-71 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHMNNKED_03105 2.9e-13
MHMNNKED_03106 7.1e-30
MHMNNKED_03108 1.1e-110 ehuB ET Bacterial periplasmic substrate-binding proteins
MHMNNKED_03109 1.3e-77 ehuC E Binding-protein-dependent transport system inner membrane component
MHMNNKED_03110 1.1e-89 ehuD E Binding-protein-dependent transport system inner membrane component
MHMNNKED_03111 1.9e-110 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)