ORF_ID e_value Gene_name EC_number CAZy COGs Description
DIGBIBDE_00001 1e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DIGBIBDE_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DIGBIBDE_00003 1.1e-29 yyzM S Protein conserved in bacteria
DIGBIBDE_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DIGBIBDE_00005 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DIGBIBDE_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DIGBIBDE_00007 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DIGBIBDE_00008 3e-60 divIC D Septum formation initiator
DIGBIBDE_00010 4.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
DIGBIBDE_00011 3.9e-237 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DIGBIBDE_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DIGBIBDE_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIGBIBDE_00026 2.6e-10
DIGBIBDE_00032 9.2e-110 mreC M Involved in formation and maintenance of cell shape
DIGBIBDE_00033 4.2e-84 mreD M rod shape-determining protein MreD
DIGBIBDE_00034 1.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
DIGBIBDE_00035 8.8e-104 L COG1943 Transposase and inactivated derivatives
DIGBIBDE_00036 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIGBIBDE_00037 1.9e-217 araT 2.6.1.1 E Aminotransferase
DIGBIBDE_00038 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
DIGBIBDE_00039 9.5e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DIGBIBDE_00040 1.8e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIGBIBDE_00041 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DIGBIBDE_00042 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIGBIBDE_00043 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DIGBIBDE_00044 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DIGBIBDE_00045 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DIGBIBDE_00046 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DIGBIBDE_00047 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
DIGBIBDE_00048 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DIGBIBDE_00049 6.4e-196 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DIGBIBDE_00050 3.1e-152
DIGBIBDE_00051 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DIGBIBDE_00052 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DIGBIBDE_00053 3.1e-69 argR K Regulates arginine biosynthesis genes
DIGBIBDE_00054 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
DIGBIBDE_00055 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIGBIBDE_00056 1.9e-77 S Protein of unknown function (DUF3021)
DIGBIBDE_00057 2.4e-69 K LytTr DNA-binding domain
DIGBIBDE_00059 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DIGBIBDE_00061 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DIGBIBDE_00062 3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
DIGBIBDE_00063 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
DIGBIBDE_00064 5.2e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DIGBIBDE_00065 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
DIGBIBDE_00071 5.3e-11
DIGBIBDE_00074 1.9e-07
DIGBIBDE_00079 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIGBIBDE_00080 3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
DIGBIBDE_00081 5.5e-36 XK27_02060 S Transglycosylase associated protein
DIGBIBDE_00082 3.9e-72 badR K Transcriptional regulator, marr family
DIGBIBDE_00083 3.8e-96 S reductase
DIGBIBDE_00085 8.3e-290 ahpF O alkyl hydroperoxide reductase
DIGBIBDE_00086 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
DIGBIBDE_00087 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
DIGBIBDE_00088 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DIGBIBDE_00089 1.2e-82 S Putative small multi-drug export protein
DIGBIBDE_00090 1.8e-75 ctsR K Belongs to the CtsR family
DIGBIBDE_00091 0.0 clpC O Belongs to the ClpA ClpB family
DIGBIBDE_00092 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DIGBIBDE_00093 1.1e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DIGBIBDE_00094 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DIGBIBDE_00095 6.7e-139 S SseB protein N-terminal domain
DIGBIBDE_00096 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
DIGBIBDE_00099 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DIGBIBDE_00100 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DIGBIBDE_00102 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIGBIBDE_00103 2.7e-91 yacP S RNA-binding protein containing a PIN domain
DIGBIBDE_00104 1.4e-153 degV S DegV family
DIGBIBDE_00106 2.7e-20 K Transcriptional
DIGBIBDE_00107 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIGBIBDE_00108 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DIGBIBDE_00109 2.6e-18
DIGBIBDE_00110 1.5e-29 K Helix-turn-helix domain
DIGBIBDE_00111 6e-85
DIGBIBDE_00112 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
DIGBIBDE_00113 6.3e-105 capA M Bacterial capsule synthesis protein
DIGBIBDE_00114 1.1e-112 capA M Bacterial capsule synthesis protein
DIGBIBDE_00115 1e-38 gcvR T UPF0237 protein
DIGBIBDE_00116 2.3e-243 XK27_08635 S UPF0210 protein
DIGBIBDE_00117 5.6e-132 ais G Phosphoglycerate mutase
DIGBIBDE_00118 1.5e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DIGBIBDE_00119 1.2e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
DIGBIBDE_00120 1.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DIGBIBDE_00121 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DIGBIBDE_00122 6e-303 dnaK O Heat shock 70 kDa protein
DIGBIBDE_00123 1.7e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
DIGBIBDE_00124 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DIGBIBDE_00125 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DIGBIBDE_00126 4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
DIGBIBDE_00127 1.5e-80 hmpT S cog cog4720
DIGBIBDE_00140 1.1e-86 sigH K DNA-templated transcription, initiation
DIGBIBDE_00141 5.8e-138 ykuT M mechanosensitive ion channel
DIGBIBDE_00142 1.5e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DIGBIBDE_00143 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DIGBIBDE_00144 4.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DIGBIBDE_00145 6.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
DIGBIBDE_00146 1.1e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
DIGBIBDE_00147 7.2e-83 XK27_02675 K Acetyltransferase GNAT Family
DIGBIBDE_00148 1.6e-177 prmA J Ribosomal protein L11 methyltransferase
DIGBIBDE_00149 5.9e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DIGBIBDE_00150 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DIGBIBDE_00151 5e-81 nrdI F Belongs to the NrdI family
DIGBIBDE_00152 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIGBIBDE_00153 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DIGBIBDE_00154 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DIGBIBDE_00155 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIGBIBDE_00156 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DIGBIBDE_00157 1.4e-110 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
DIGBIBDE_00158 1.4e-193 yhjX P Major Facilitator
DIGBIBDE_00159 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DIGBIBDE_00160 9.5e-85 V VanZ like family
DIGBIBDE_00161 9.3e-185 D nuclear chromosome segregation
DIGBIBDE_00162 2.2e-123 glnQ E abc transporter atp-binding protein
DIGBIBDE_00163 1.2e-272 glnP P ABC transporter
DIGBIBDE_00164 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DIGBIBDE_00165 8.3e-18 S Protein of unknown function (DUF3021)
DIGBIBDE_00166 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DIGBIBDE_00167 5.1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
DIGBIBDE_00168 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DIGBIBDE_00169 2e-233 sufD O assembly protein SufD
DIGBIBDE_00170 1.7e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIGBIBDE_00171 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
DIGBIBDE_00172 1e-273 sufB O assembly protein SufB
DIGBIBDE_00173 2.3e-311 oppA E ABC transporter substrate-binding protein
DIGBIBDE_00174 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIGBIBDE_00175 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIGBIBDE_00176 6.6e-198 oppD P Belongs to the ABC transporter superfamily
DIGBIBDE_00177 4.1e-167 oppF P Belongs to the ABC transporter superfamily
DIGBIBDE_00178 3e-25
DIGBIBDE_00179 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DIGBIBDE_00180 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIGBIBDE_00181 5.9e-71 adcR K transcriptional
DIGBIBDE_00182 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
DIGBIBDE_00183 9.6e-128 adcB P ABC transporter (Permease
DIGBIBDE_00184 2.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
DIGBIBDE_00185 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
DIGBIBDE_00186 1.5e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
DIGBIBDE_00187 5.3e-256 pgi 5.3.1.9 G Belongs to the GPI family
DIGBIBDE_00188 1.5e-150 Z012_04635 K sequence-specific DNA binding
DIGBIBDE_00189 1.5e-281 V ABC transporter
DIGBIBDE_00190 6.1e-126 yeeN K transcriptional regulatory protein
DIGBIBDE_00191 7.7e-47 yajC U protein transport
DIGBIBDE_00192 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIGBIBDE_00193 4.8e-140 cdsA 2.7.7.41 S Belongs to the CDS family
DIGBIBDE_00194 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DIGBIBDE_00195 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DIGBIBDE_00196 0.0 WQ51_06230 S ABC transporter
DIGBIBDE_00197 1.4e-142 cmpC S abc transporter atp-binding protein
DIGBIBDE_00198 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DIGBIBDE_00199 2.2e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DIGBIBDE_00201 5.5e-44
DIGBIBDE_00202 5.8e-55 S TM2 domain
DIGBIBDE_00203 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DIGBIBDE_00204 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DIGBIBDE_00205 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DIGBIBDE_00206 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
DIGBIBDE_00207 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
DIGBIBDE_00208 4.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
DIGBIBDE_00209 5.8e-149 cof S Sucrose-6F-phosphate phosphohydrolase
DIGBIBDE_00210 4.8e-137 glcR K transcriptional regulator (DeoR family)
DIGBIBDE_00211 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DIGBIBDE_00212 9.6e-77 K transcriptional
DIGBIBDE_00213 1.4e-239 S COG1073 Hydrolases of the alpha beta superfamily
DIGBIBDE_00214 1.2e-25 yjdF S Protein of unknown function (DUF2992)
DIGBIBDE_00215 2.8e-157 cylA V abc transporter atp-binding protein
DIGBIBDE_00216 5.1e-132 cylB V ABC-2 type transporter
DIGBIBDE_00217 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
DIGBIBDE_00218 6.8e-32 S Protein of unknown function (DUF3021)
DIGBIBDE_00219 2.1e-123 mta K Transcriptional
DIGBIBDE_00220 6.2e-120 yhcA V abc transporter atp-binding protein
DIGBIBDE_00221 1.5e-215 macB_2 V FtsX-like permease family
DIGBIBDE_00222 3.9e-273 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DIGBIBDE_00223 2e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DIGBIBDE_00224 5.7e-74 yhaI S Protein of unknown function (DUF805)
DIGBIBDE_00225 2.6e-255 pepC 3.4.22.40 E aminopeptidase
DIGBIBDE_00226 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DIGBIBDE_00227 8.1e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DIGBIBDE_00228 1.2e-94 ypsA S Belongs to the UPF0398 family
DIGBIBDE_00229 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DIGBIBDE_00230 3.9e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DIGBIBDE_00231 4.7e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
DIGBIBDE_00232 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
DIGBIBDE_00233 7.4e-23
DIGBIBDE_00234 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DIGBIBDE_00235 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
DIGBIBDE_00236 1.6e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIGBIBDE_00237 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DIGBIBDE_00238 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DIGBIBDE_00239 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DIGBIBDE_00240 4.6e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIGBIBDE_00241 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
DIGBIBDE_00242 6.9e-103 ybhL S Belongs to the BI1 family
DIGBIBDE_00243 1.6e-11 ycdA S Domain of unknown function (DUF4352)
DIGBIBDE_00244 6.2e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DIGBIBDE_00245 1.4e-90 K transcriptional regulator
DIGBIBDE_00246 1.6e-36 yneF S UPF0154 protein
DIGBIBDE_00247 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DIGBIBDE_00248 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DIGBIBDE_00249 3.9e-98 XK27_09740 S Phosphoesterase
DIGBIBDE_00250 8.3e-87 ykuL S CBS domain
DIGBIBDE_00251 1e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
DIGBIBDE_00252 5.9e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIGBIBDE_00253 4.2e-93 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIGBIBDE_00254 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DIGBIBDE_00255 4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
DIGBIBDE_00256 7.9e-258 trkH P Cation transport protein
DIGBIBDE_00257 1e-246 trkA P Potassium transporter peripheral membrane component
DIGBIBDE_00258 2e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DIGBIBDE_00259 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DIGBIBDE_00260 4.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
DIGBIBDE_00261 7.3e-153 K sequence-specific DNA binding
DIGBIBDE_00262 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DIGBIBDE_00263 3.3e-50 yhaI L Membrane
DIGBIBDE_00264 9.3e-248 S Domain of unknown function (DUF4173)
DIGBIBDE_00265 6.8e-95 ureI S AmiS/UreI family transporter
DIGBIBDE_00266 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
DIGBIBDE_00267 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
DIGBIBDE_00268 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DIGBIBDE_00269 6.6e-78 ureE O enzyme active site formation
DIGBIBDE_00270 2.9e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DIGBIBDE_00271 3.6e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DIGBIBDE_00272 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DIGBIBDE_00273 7.9e-177 cbiM P PDGLE domain
DIGBIBDE_00274 1.9e-136 P cobalt transport protein
DIGBIBDE_00275 7.7e-129 cbiO P ABC transporter
DIGBIBDE_00276 1.8e-137 ET ABC transporter substrate-binding protein
DIGBIBDE_00277 1.7e-162 metQ M Belongs to the NlpA lipoprotein family
DIGBIBDE_00278 9.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
DIGBIBDE_00279 3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIGBIBDE_00280 1.2e-99 metI P ABC transporter (Permease
DIGBIBDE_00281 4.3e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DIGBIBDE_00282 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
DIGBIBDE_00283 3e-93 S UPF0397 protein
DIGBIBDE_00284 1.6e-310 ykoD P abc transporter atp-binding protein
DIGBIBDE_00285 2e-149 cbiQ P cobalt transport
DIGBIBDE_00286 1.5e-118 ktrA P COG0569 K transport systems, NAD-binding component
DIGBIBDE_00287 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
DIGBIBDE_00288 3.2e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
DIGBIBDE_00289 5.2e-90 yceD K metal-binding, possibly nucleic acid-binding protein
DIGBIBDE_00290 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_00291 4.9e-282 T PhoQ Sensor
DIGBIBDE_00292 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DIGBIBDE_00293 2.3e-215 dnaB L Replication initiation and membrane attachment
DIGBIBDE_00294 1.5e-166 dnaI L Primosomal protein DnaI
DIGBIBDE_00295 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DIGBIBDE_00296 1.1e-102
DIGBIBDE_00297 9.8e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIGBIBDE_00298 2.5e-62 manO S protein conserved in bacteria
DIGBIBDE_00299 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
DIGBIBDE_00300 1.7e-116 manM G pts system
DIGBIBDE_00301 4.9e-174 manL 2.7.1.191 G pts system
DIGBIBDE_00302 3.4e-67 manO S Protein conserved in bacteria
DIGBIBDE_00303 1.9e-164 manN G PTS system mannose fructose sorbose family IID component
DIGBIBDE_00304 1.4e-134 manY G pts system
DIGBIBDE_00305 6.2e-169 manL 2.7.1.191 G pts system
DIGBIBDE_00306 2.1e-131 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
DIGBIBDE_00307 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
DIGBIBDE_00308 2.1e-247 pbuO S permease
DIGBIBDE_00309 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
DIGBIBDE_00310 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
DIGBIBDE_00311 2.8e-211 brpA K Transcriptional
DIGBIBDE_00312 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
DIGBIBDE_00313 2.4e-196 nusA K Participates in both transcription termination and antitermination
DIGBIBDE_00314 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
DIGBIBDE_00315 1.5e-46 ylxQ J ribosomal protein
DIGBIBDE_00316 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DIGBIBDE_00317 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DIGBIBDE_00318 7.7e-100 yvdD 3.2.2.10 S Belongs to the LOG family
DIGBIBDE_00319 8.7e-273 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIGBIBDE_00320 8.6e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
DIGBIBDE_00321 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
DIGBIBDE_00322 5.1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
DIGBIBDE_00323 1.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DIGBIBDE_00324 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
DIGBIBDE_00325 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
DIGBIBDE_00326 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DIGBIBDE_00327 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DIGBIBDE_00328 3e-72 ylbF S Belongs to the UPF0342 family
DIGBIBDE_00329 1.9e-46 ylbG S UPF0298 protein
DIGBIBDE_00330 7e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
DIGBIBDE_00331 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
DIGBIBDE_00332 8.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
DIGBIBDE_00333 2.4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
DIGBIBDE_00334 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
DIGBIBDE_00335 6.6e-111 acuB S CBS domain
DIGBIBDE_00336 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DIGBIBDE_00337 2.2e-108 yvyE 3.4.13.9 S YigZ family
DIGBIBDE_00338 1.3e-235 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DIGBIBDE_00339 2e-83 comFC K competence protein
DIGBIBDE_00340 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DIGBIBDE_00348 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
DIGBIBDE_00349 1.4e-107 S Domain of unknown function (DUF1803)
DIGBIBDE_00350 7.8e-102 ygaC J Belongs to the UPF0374 family
DIGBIBDE_00351 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
DIGBIBDE_00352 1.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIGBIBDE_00353 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
DIGBIBDE_00354 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
DIGBIBDE_00355 1.7e-116 S HAD hydrolase, family IA, variant 3
DIGBIBDE_00356 1.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
DIGBIBDE_00357 5.2e-72 marR K Transcriptional regulator, MarR family
DIGBIBDE_00358 6.4e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIGBIBDE_00359 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIGBIBDE_00360 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
DIGBIBDE_00361 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DIGBIBDE_00362 6.2e-126 IQ reductase
DIGBIBDE_00363 5.7e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DIGBIBDE_00364 2.5e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DIGBIBDE_00365 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DIGBIBDE_00366 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DIGBIBDE_00367 3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DIGBIBDE_00368 5.7e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DIGBIBDE_00369 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DIGBIBDE_00370 2.7e-206 rny D Endoribonuclease that initiates mRNA decay
DIGBIBDE_00371 2e-124 fruR K transcriptional
DIGBIBDE_00372 1.3e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DIGBIBDE_00373 0.0 fruA 2.7.1.202 G phosphotransferase system
DIGBIBDE_00374 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIGBIBDE_00375 6.5e-232 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DIGBIBDE_00377 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
DIGBIBDE_00378 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIGBIBDE_00379 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DIGBIBDE_00380 6.7e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DIGBIBDE_00381 7.1e-95 2.3.1.128 K acetyltransferase
DIGBIBDE_00382 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DIGBIBDE_00383 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DIGBIBDE_00384 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIGBIBDE_00385 5e-63 WQ51_03320 S cog cog4835
DIGBIBDE_00386 1.4e-150 XK27_08360 S EDD domain protein, DegV family
DIGBIBDE_00387 5.7e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DIGBIBDE_00388 5.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DIGBIBDE_00389 0.0 yfmR S abc transporter atp-binding protein
DIGBIBDE_00390 1e-26 U response to pH
DIGBIBDE_00391 8.1e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
DIGBIBDE_00392 1.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
DIGBIBDE_00393 4.1e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DIGBIBDE_00394 8.7e-36 S Psort location CytoplasmicMembrane, score
DIGBIBDE_00395 3.4e-239 S Psort location CytoplasmicMembrane, score
DIGBIBDE_00396 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DIGBIBDE_00397 3.3e-74 K DNA-binding transcription factor activity
DIGBIBDE_00398 5e-310 lmrA1 V abc transporter atp-binding protein
DIGBIBDE_00399 0.0 lmrA2 V abc transporter atp-binding protein
DIGBIBDE_00400 3.3e-112 K Acetyltransferase (GNAT) family
DIGBIBDE_00401 5.1e-113 2.7.6.5 S Region found in RelA / SpoT proteins
DIGBIBDE_00402 1.7e-117 T response regulator
DIGBIBDE_00403 8.5e-213 sptS 2.7.13.3 T Histidine kinase
DIGBIBDE_00404 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DIGBIBDE_00405 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DIGBIBDE_00406 4.5e-160 cvfB S Protein conserved in bacteria
DIGBIBDE_00407 3.7e-34 yozE S Belongs to the UPF0346 family
DIGBIBDE_00408 1.1e-125 sip M LysM domain protein
DIGBIBDE_00409 1.3e-188 phoH T phosphate starvation-inducible protein PhoH
DIGBIBDE_00410 9.3e-164 L Transposase
DIGBIBDE_00415 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIGBIBDE_00416 9.6e-163 S reductase
DIGBIBDE_00417 4.7e-168 K transcriptional regulator (lysR family)
DIGBIBDE_00418 1.4e-104 S CAAX amino terminal protease family protein
DIGBIBDE_00419 2.5e-307 S Glucan-binding protein C
DIGBIBDE_00420 7.3e-163 S CHAP domain
DIGBIBDE_00421 1.9e-23 L overlaps another CDS with the same product name
DIGBIBDE_00422 5.9e-23 insK L Integrase core domain protein
DIGBIBDE_00423 5.2e-33 L transposition
DIGBIBDE_00424 9.1e-178 coiA 3.6.4.12 S Competence protein
DIGBIBDE_00425 0.0 pepF E oligoendopeptidase F
DIGBIBDE_00426 3.8e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
DIGBIBDE_00427 2.1e-126 yrrM 2.1.1.104 S O-Methyltransferase
DIGBIBDE_00428 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
DIGBIBDE_00429 3e-84 yxjI S LURP-one-related
DIGBIBDE_00430 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIGBIBDE_00431 2.7e-163 K sequence-specific DNA binding
DIGBIBDE_00432 1.2e-09
DIGBIBDE_00434 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DIGBIBDE_00435 4.3e-138 agrA KT response regulator
DIGBIBDE_00436 3.1e-07
DIGBIBDE_00437 5.6e-135 agrA KT response regulator
DIGBIBDE_00438 2e-231 2.7.13.3 T GHKL domain
DIGBIBDE_00440 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
DIGBIBDE_00441 2.8e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DIGBIBDE_00442 9.1e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
DIGBIBDE_00443 1.1e-186 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DIGBIBDE_00444 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DIGBIBDE_00445 7.4e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DIGBIBDE_00446 9.4e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
DIGBIBDE_00447 7.9e-128 yxkH G deacetylase
DIGBIBDE_00448 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DIGBIBDE_00449 8.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DIGBIBDE_00450 2e-147 rarD S Transporter
DIGBIBDE_00451 1.4e-17 T peptidase
DIGBIBDE_00452 3e-14 coiA 3.6.4.12 S Competence protein
DIGBIBDE_00453 2.7e-108 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIGBIBDE_00454 1.2e-105 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DIGBIBDE_00455 7.2e-175 S Helix-hairpin-helix DNA-binding motif class 1
DIGBIBDE_00456 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DIGBIBDE_00458 3.5e-56 lrgA S Effector of murein hydrolase LrgA
DIGBIBDE_00459 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DIGBIBDE_00460 5.5e-98 3.1.3.18 S IA, variant 1
DIGBIBDE_00461 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIGBIBDE_00462 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DIGBIBDE_00463 9.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
DIGBIBDE_00464 2.5e-07 N PFAM Uncharacterised protein family UPF0150
DIGBIBDE_00465 1.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
DIGBIBDE_00467 1.9e-62 ycaO O OsmC-like protein
DIGBIBDE_00468 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
DIGBIBDE_00469 5.7e-10 O ADP-ribosylglycohydrolase
DIGBIBDE_00470 5.8e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DIGBIBDE_00472 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DIGBIBDE_00473 1.7e-17 XK27_00735
DIGBIBDE_00474 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_00475 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
DIGBIBDE_00476 7.1e-159 S CAAX amino terminal protease family protein
DIGBIBDE_00478 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DIGBIBDE_00480 4.1e-83 mutT 3.6.1.55 F Nudix family
DIGBIBDE_00481 1.9e-136 ET ABC transporter
DIGBIBDE_00482 1e-137 ET Belongs to the bacterial solute-binding protein 3 family
DIGBIBDE_00483 4e-201 arcT 2.6.1.1 E Aminotransferase
DIGBIBDE_00484 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
DIGBIBDE_00485 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DIGBIBDE_00486 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DIGBIBDE_00487 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DIGBIBDE_00488 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DIGBIBDE_00489 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
DIGBIBDE_00490 3.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
DIGBIBDE_00491 4.3e-267 S Glucosyl transferase GtrII
DIGBIBDE_00492 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DIGBIBDE_00493 3.8e-227 amrA S membrane protein involved in the export of O-antigen and teichoic acid
DIGBIBDE_00494 6.5e-187 M Glycosyltransferase group 2 family protein
DIGBIBDE_00495 6.5e-128 arnC M group 2 family protein
DIGBIBDE_00496 1.8e-46 S Uncharacterized conserved protein (DUF2304)
DIGBIBDE_00497 1.1e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
DIGBIBDE_00498 5.1e-117
DIGBIBDE_00499 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
DIGBIBDE_00500 1.7e-221 M Psort location CytoplasmicMembrane, score
DIGBIBDE_00501 6.9e-234 GT4 M transferase activity, transferring glycosyl groups
DIGBIBDE_00502 1.5e-259 S Glucosyl transferase GtrII
DIGBIBDE_00503 5.4e-225 rgpA GT4 M Domain of unknown function (DUF1972)
DIGBIBDE_00504 1.2e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
DIGBIBDE_00505 6.8e-142 rgpC GM Transport permease protein
DIGBIBDE_00506 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DIGBIBDE_00507 1.5e-305 rgpF M Rhamnan synthesis protein F
DIGBIBDE_00508 1.8e-114 radC E Belongs to the UPF0758 family
DIGBIBDE_00509 2.4e-127 puuD T peptidase C26
DIGBIBDE_00510 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DIGBIBDE_00511 8.2e-60 XK27_04120 S Putative amino acid metabolism
DIGBIBDE_00512 4.3e-203 iscS 2.8.1.7 E Cysteine desulfurase
DIGBIBDE_00513 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIGBIBDE_00514 7.1e-101 yjbK S Adenylate cyclase
DIGBIBDE_00515 2e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
DIGBIBDE_00516 1.3e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIGBIBDE_00517 5.9e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DIGBIBDE_00518 4.8e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DIGBIBDE_00519 0.0 amiA E ABC transporter, substrate-binding protein, family 5
DIGBIBDE_00520 1.9e-278 amiC P ABC transporter (Permease
DIGBIBDE_00521 2e-166 amiD P ABC transporter (Permease
DIGBIBDE_00522 4.2e-203 oppD P Belongs to the ABC transporter superfamily
DIGBIBDE_00523 3.6e-171 oppF P Belongs to the ABC transporter superfamily
DIGBIBDE_00524 9.9e-130 V Psort location CytoplasmicMembrane, score
DIGBIBDE_00525 5.4e-119 skfE V abc transporter atp-binding protein
DIGBIBDE_00526 1.9e-62 yvoA_1 K Transcriptional
DIGBIBDE_00527 2e-146 supH S overlaps another CDS with the same product name
DIGBIBDE_00528 2.1e-146 XK27_02985 S overlaps another CDS with the same product name
DIGBIBDE_00529 3.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DIGBIBDE_00530 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DIGBIBDE_00531 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
DIGBIBDE_00532 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIGBIBDE_00533 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DIGBIBDE_00534 3.6e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DIGBIBDE_00535 2.4e-136 stp 3.1.3.16 T phosphatase
DIGBIBDE_00536 1e-289 prkC 2.7.11.1 KLT serine threonine protein kinase
DIGBIBDE_00537 4.1e-104 kcsA P Ion transport protein
DIGBIBDE_00538 8.6e-117 yvqF S Membrane
DIGBIBDE_00539 3.9e-171 vraS 2.7.13.3 T Histidine kinase
DIGBIBDE_00540 4.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DIGBIBDE_00543 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIGBIBDE_00544 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DIGBIBDE_00545 1.3e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DIGBIBDE_00546 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DIGBIBDE_00547 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DIGBIBDE_00548 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DIGBIBDE_00549 3.1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIGBIBDE_00550 2.8e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
DIGBIBDE_00551 3.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
DIGBIBDE_00552 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DIGBIBDE_00553 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
DIGBIBDE_00554 5.7e-291 S Protein of unknown function (DUF3114)
DIGBIBDE_00556 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
DIGBIBDE_00557 8e-297 V abc transporter atp-binding protein
DIGBIBDE_00558 0.0 V abc transporter atp-binding protein
DIGBIBDE_00559 1.9e-193 XK27_10075 S abc transporter atp-binding protein
DIGBIBDE_00560 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
DIGBIBDE_00561 0.0 M Pilin isopeptide linkage domain protein
DIGBIBDE_00562 0.0 M Pilin isopeptide linkage domain protein
DIGBIBDE_00563 0.0 zmpB M signal peptide protein, YSIRK family
DIGBIBDE_00564 0.0 GM domain, Protein
DIGBIBDE_00565 1.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DIGBIBDE_00566 0.0 sbcC L ATPase involved in DNA repair
DIGBIBDE_00567 2.8e-29 1.3.5.4 C reductase
DIGBIBDE_00568 3.4e-155 cat 2.3.1.28 S acetyltransferase'
DIGBIBDE_00569 0.0 M family 8
DIGBIBDE_00570 1e-146 epsH S acetyltransferase'
DIGBIBDE_00571 2e-238 M Glycosyltransferase, family 8
DIGBIBDE_00572 1.2e-288 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DIGBIBDE_00573 1.4e-194 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DIGBIBDE_00574 1.6e-185 nss M transferase activity, transferring glycosyl groups
DIGBIBDE_00575 1.4e-231 M Glycosyltransferase, family 8
DIGBIBDE_00576 5.1e-167 cpsJ M Glycosyltransferase group 2 family protein
DIGBIBDE_00577 0.0 M cog cog1442
DIGBIBDE_00578 1.3e-240 M family 8
DIGBIBDE_00579 5.1e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
DIGBIBDE_00580 1.8e-308 asp1 S Accessory Sec system protein Asp1
DIGBIBDE_00581 3.2e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
DIGBIBDE_00582 1.6e-68 asp3 S Accessory Sec system protein Asp3
DIGBIBDE_00583 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DIGBIBDE_00584 3.9e-13 S Accessory secretory protein Sec Asp4
DIGBIBDE_00585 7e-12 S Accessory secretory protein Sec, Asp5
DIGBIBDE_00587 1.2e-16 3.2.1.51 GH95 U LPXTG cell wall anchor motif
DIGBIBDE_00588 8e-34 K the current gene model (or a revised gene model) may contain a frame shift
DIGBIBDE_00589 4.4e-68 K Helix-turn-helix domain, rpiR family
DIGBIBDE_00590 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_00591 0.0 3.5.1.28 M domain protein
DIGBIBDE_00592 4.3e-87 V abc transporter atp-binding protein
DIGBIBDE_00593 1.2e-13
DIGBIBDE_00595 1.1e-73 K Transcriptional regulatory protein, C terminal
DIGBIBDE_00596 4.4e-64 2.7.13.3 T Histidine kinase
DIGBIBDE_00597 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
DIGBIBDE_00598 4e-66 rmaI K Transcriptional regulator, MarR family
DIGBIBDE_00599 5.4e-240 EGP Major facilitator Superfamily
DIGBIBDE_00600 6.2e-129 XK27_00785 S CAAX protease self-immunity
DIGBIBDE_00602 0.0 S dextransucrase activity
DIGBIBDE_00603 0.0 S dextransucrase activity
DIGBIBDE_00604 1.9e-286 S dextransucrase activity
DIGBIBDE_00605 0.0 M Putative cell wall binding repeat
DIGBIBDE_00606 2.4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DIGBIBDE_00607 2.4e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DIGBIBDE_00608 1.6e-62
DIGBIBDE_00609 0.0 S dextransucrase activity
DIGBIBDE_00610 2.3e-231 tcdB S dextransucrase activity
DIGBIBDE_00611 1.4e-89 M Putative cell wall binding repeat
DIGBIBDE_00612 0.0 S dextransucrase activity
DIGBIBDE_00613 0.0 S dextransucrase activity
DIGBIBDE_00614 0.0 S dextransucrase activity
DIGBIBDE_00615 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_00616 3.1e-45 U relaxase
DIGBIBDE_00617 1.7e-246 T PhoQ Sensor
DIGBIBDE_00618 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_00619 1.2e-07 S Type-A lantibiotic
DIGBIBDE_00620 1.6e-07 S Type-A lantibiotic
DIGBIBDE_00622 0.0 lcnDR2 V Lanthionine synthetase C-like protein
DIGBIBDE_00623 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DIGBIBDE_00624 3.4e-166 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
DIGBIBDE_00625 1.8e-128
DIGBIBDE_00626 9.7e-111 S ABC-2 family transporter protein
DIGBIBDE_00627 2.4e-24 K transcriptional
DIGBIBDE_00628 1.5e-13 ymbI L PFAM transposase IS3 IS911 family protein
DIGBIBDE_00629 5e-40 L COG2801 Transposase and inactivated derivatives
DIGBIBDE_00630 3.7e-250 S dextransucrase activity
DIGBIBDE_00632 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_00633 2e-116 yhfC S Putative membrane peptidase family (DUF2324)
DIGBIBDE_00634 2.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
DIGBIBDE_00635 2.1e-15 S integral membrane protein
DIGBIBDE_00636 2.4e-08 S Enterocin A Immunity
DIGBIBDE_00637 1.3e-271 L Transposase
DIGBIBDE_00638 0.0 pepO 3.4.24.71 O Peptidase family M13
DIGBIBDE_00639 4.1e-34 S Immunity protein 41
DIGBIBDE_00640 2.5e-84 M Putative cell wall binding repeat
DIGBIBDE_00641 0.0 M Putative cell wall binding repeat
DIGBIBDE_00642 2.2e-224 thrE K Psort location CytoplasmicMembrane, score
DIGBIBDE_00643 3.2e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
DIGBIBDE_00644 2.9e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
DIGBIBDE_00645 2.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
DIGBIBDE_00646 5.3e-181 XK27_10475 S oxidoreductase
DIGBIBDE_00647 1.2e-32 BP1961 P oxidoreductase
DIGBIBDE_00648 1.3e-160 BP1961 P oxidoreductase
DIGBIBDE_00650 5.6e-283 XK27_07020 S Belongs to the UPF0371 family
DIGBIBDE_00651 1.5e-180 vex1 V Efflux ABC transporter, permease protein
DIGBIBDE_00652 1.9e-107 vex2 V abc transporter atp-binding protein
DIGBIBDE_00653 1.2e-236 vex3 V Efflux ABC transporter, permease protein
DIGBIBDE_00654 5.2e-116 K Response regulator receiver domain protein
DIGBIBDE_00655 5.2e-216 vncS 2.7.13.3 T Histidine kinase
DIGBIBDE_00656 1.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
DIGBIBDE_00657 4.9e-182 galR K Transcriptional regulator
DIGBIBDE_00658 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DIGBIBDE_00659 3.2e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DIGBIBDE_00660 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DIGBIBDE_00661 1.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DIGBIBDE_00662 0.0 lacS G transporter
DIGBIBDE_00663 0.0 lacL 3.2.1.23 G -beta-galactosidase
DIGBIBDE_00664 1e-196 S Tetratricopeptide repeat
DIGBIBDE_00665 3.5e-157 yvgN C reductase
DIGBIBDE_00666 2.5e-30 XK27_10490
DIGBIBDE_00667 4e-40 DJ nuclease activity
DIGBIBDE_00668 1.8e-106 yoaK S Protein of unknown function (DUF1275)
DIGBIBDE_00669 1e-108 drgA C nitroreductase
DIGBIBDE_00670 4e-119 T Xre family transcriptional regulator
DIGBIBDE_00671 6.7e-127 T PhoQ Sensor
DIGBIBDE_00672 4.3e-45 S Domain of unknown function (DUF4352)
DIGBIBDE_00673 3.4e-127 S ABC-2 family transporter protein
DIGBIBDE_00674 2.6e-80 bcrA V abc transporter atp-binding protein
DIGBIBDE_00675 1.1e-206 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DIGBIBDE_00676 4.9e-154 E Alpha/beta hydrolase of unknown function (DUF915)
DIGBIBDE_00677 4.7e-76 ywnA K Transcriptional regulator
DIGBIBDE_00678 1.5e-152 1.13.11.2 S glyoxalase
DIGBIBDE_00679 2.2e-108 XK27_02070 S nitroreductase
DIGBIBDE_00680 1.3e-35
DIGBIBDE_00681 5.5e-27 XK27_07105 K transcriptional
DIGBIBDE_00682 1.4e-09 S Protein of unknown function (DUF3169)
DIGBIBDE_00683 9.8e-166 natA S abc transporter atp-binding protein
DIGBIBDE_00684 2.1e-211 natB CP ABC-type Na efflux pump, permease component
DIGBIBDE_00685 4e-170 ydhF S Aldo keto reductase
DIGBIBDE_00686 2.1e-97 K WHG domain
DIGBIBDE_00687 6.6e-122 V abc transporter atp-binding protein
DIGBIBDE_00688 8.9e-204 P FtsX-like permease family
DIGBIBDE_00689 1.5e-42 S Sugar efflux transporter for intercellular exchange
DIGBIBDE_00690 2.3e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
DIGBIBDE_00691 9.5e-178 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
DIGBIBDE_00692 4.7e-165 ET ABC transporter substrate-binding protein
DIGBIBDE_00693 1.1e-111 ytmL P ABC transporter (Permease
DIGBIBDE_00694 1.9e-113 yxeN P ABC transporter, permease protein
DIGBIBDE_00695 2.5e-138 tcyC2 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_00696 0.0 S dextransucrase activity
DIGBIBDE_00697 2.1e-215 yfnA E amino acid
DIGBIBDE_00698 3.4e-126 S Carbohydrate-binding domain-containing protein Cthe_2159
DIGBIBDE_00699 1.4e-16 csbD S CsbD-like
DIGBIBDE_00700 1.5e-107 S Protein of unknown function (DUF421)
DIGBIBDE_00701 1.8e-59 S Protein of unknown function (DUF3290)
DIGBIBDE_00702 7.3e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
DIGBIBDE_00703 3.6e-233 brnQ E Component of the transport system for branched-chain amino acids
DIGBIBDE_00704 1.5e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIGBIBDE_00706 8.7e-243 norM V Multidrug efflux pump
DIGBIBDE_00707 2.6e-152 K sequence-specific DNA binding
DIGBIBDE_00708 6.7e-143 V (ABC) transporter
DIGBIBDE_00709 2.7e-118 V (ABC) transporter
DIGBIBDE_00710 4.5e-59 pdxH S pyridoxamine 5'-phosphate oxidase
DIGBIBDE_00711 1.1e-223 pbuX F xanthine permease
DIGBIBDE_00712 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DIGBIBDE_00713 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_00714 2e-151 T Histidine kinase
DIGBIBDE_00715 8.4e-134 macB2 V ABC transporter, ATP-binding protein
DIGBIBDE_00716 2.3e-308 V ABC transporter (permease)
DIGBIBDE_00717 4e-92 XK27_05000 S metal cluster binding
DIGBIBDE_00718 2.2e-29 liaI KT membrane
DIGBIBDE_00719 3.4e-17 liaI KT membrane
DIGBIBDE_00720 1.1e-156 XK27_09825 V abc transporter atp-binding protein
DIGBIBDE_00721 2e-116 yvfS V Transporter
DIGBIBDE_00722 2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
DIGBIBDE_00723 3.3e-164 yocS S Transporter
DIGBIBDE_00726 4.1e-156 XK27_09825 V 'abc transporter, ATP-binding protein
DIGBIBDE_00727 2e-132 yvfS V ABC-2 type transporter
DIGBIBDE_00728 1.1e-187 desK 2.7.13.3 T Histidine kinase
DIGBIBDE_00729 2.6e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DIGBIBDE_00730 2.1e-80
DIGBIBDE_00731 3.3e-16
DIGBIBDE_00733 2.2e-20
DIGBIBDE_00734 7.8e-86
DIGBIBDE_00735 1.2e-46
DIGBIBDE_00736 1e-173 L Integrase
DIGBIBDE_00737 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
DIGBIBDE_00738 1.2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
DIGBIBDE_00739 9.4e-121 sdaAB 4.3.1.17 E L-serine dehydratase
DIGBIBDE_00740 1.6e-103
DIGBIBDE_00741 6.3e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
DIGBIBDE_00742 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DIGBIBDE_00743 1.3e-271 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIGBIBDE_00744 1.2e-88 pat 2.3.1.183 M acetyltransferase
DIGBIBDE_00745 2.1e-296 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIGBIBDE_00746 7.7e-120 alkD L Dna alkylation repair
DIGBIBDE_00747 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DIGBIBDE_00748 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIGBIBDE_00749 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DIGBIBDE_00750 0.0 smc D Required for chromosome condensation and partitioning
DIGBIBDE_00751 1e-93 S Protein of unknown function (DUF3278)
DIGBIBDE_00752 2.9e-22 WQ51_00220 K Helix-turn-helix domain
DIGBIBDE_00753 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DIGBIBDE_00754 1.7e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DIGBIBDE_00755 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DIGBIBDE_00757 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
DIGBIBDE_00758 1.4e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DIGBIBDE_00760 9.4e-81 S ECF-type riboflavin transporter, S component
DIGBIBDE_00761 1e-143 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
DIGBIBDE_00762 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
DIGBIBDE_00763 1.1e-294 yfmM S abc transporter atp-binding protein
DIGBIBDE_00764 1.4e-256 noxE P NADH oxidase
DIGBIBDE_00765 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DIGBIBDE_00766 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIGBIBDE_00767 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
DIGBIBDE_00768 4.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
DIGBIBDE_00769 6.4e-163 ypuA S secreted protein
DIGBIBDE_00770 3.9e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
DIGBIBDE_00771 4.4e-45 rpmE2 J 50S ribosomal protein L31
DIGBIBDE_00772 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DIGBIBDE_00773 2.2e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
DIGBIBDE_00774 1.2e-151 gst O Glutathione S-transferase
DIGBIBDE_00775 5.3e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DIGBIBDE_00776 1.9e-109 tdk 2.7.1.21 F thymidine kinase
DIGBIBDE_00777 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIGBIBDE_00778 3.7e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DIGBIBDE_00779 3.4e-101 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DIGBIBDE_00780 1.3e-62 XK27_05710 K Acetyltransferase (GNAT) domain
DIGBIBDE_00781 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIGBIBDE_00782 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
DIGBIBDE_00783 1.4e-99 pvaA M lytic transglycosylase activity
DIGBIBDE_00784 2.9e-291 yfiB1 V abc transporter atp-binding protein
DIGBIBDE_00785 0.0 XK27_10035 V abc transporter atp-binding protein
DIGBIBDE_00786 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DIGBIBDE_00787 4.3e-236 dltB M Membrane protein involved in D-alanine export
DIGBIBDE_00788 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DIGBIBDE_00789 7.4e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DIGBIBDE_00790 0.0 3.6.3.8 P cation transport ATPase
DIGBIBDE_00791 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
DIGBIBDE_00793 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIGBIBDE_00794 3.3e-166 metF 1.5.1.20 E reductase
DIGBIBDE_00795 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
DIGBIBDE_00796 2.9e-91 panT S Psort location CytoplasmicMembrane, score
DIGBIBDE_00797 6.4e-94 panT S ECF transporter, substrate-specific component
DIGBIBDE_00798 3.3e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIGBIBDE_00799 3.5e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
DIGBIBDE_00800 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DIGBIBDE_00801 2.5e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_00802 3.3e-240 T PhoQ Sensor
DIGBIBDE_00803 1e-29 rpsT J Binds directly to 16S ribosomal RNA
DIGBIBDE_00804 6.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
DIGBIBDE_00805 5.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
DIGBIBDE_00806 4.7e-230 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
DIGBIBDE_00807 3.2e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DIGBIBDE_00808 2.5e-68 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DIGBIBDE_00809 2.5e-192 tcsA S membrane
DIGBIBDE_00810 4.1e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
DIGBIBDE_00811 1.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
DIGBIBDE_00812 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
DIGBIBDE_00813 5.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
DIGBIBDE_00814 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DIGBIBDE_00815 1.5e-80 ypmB S Protein conserved in bacteria
DIGBIBDE_00816 1e-210 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DIGBIBDE_00817 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DIGBIBDE_00818 1.4e-18
DIGBIBDE_00819 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
DIGBIBDE_00820 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DIGBIBDE_00821 3.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
DIGBIBDE_00822 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DIGBIBDE_00823 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
DIGBIBDE_00824 5.6e-201 D nuclear chromosome segregation
DIGBIBDE_00825 1.4e-136 yejC S cyclic nucleotide-binding protein
DIGBIBDE_00826 1.6e-163 rapZ S Displays ATPase and GTPase activities
DIGBIBDE_00827 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DIGBIBDE_00828 2.2e-160 whiA K May be required for sporulation
DIGBIBDE_00829 4e-275 pepD E Dipeptidase
DIGBIBDE_00830 7.1e-147 XK27_10720 D peptidase activity
DIGBIBDE_00831 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
DIGBIBDE_00832 2.6e-09
DIGBIBDE_00834 1.4e-168 yeiH S Membrane
DIGBIBDE_00835 3.8e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
DIGBIBDE_00836 2.9e-165 cpsY K Transcriptional regulator
DIGBIBDE_00837 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DIGBIBDE_00838 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
DIGBIBDE_00839 1.4e-105 artQ P ABC transporter (Permease
DIGBIBDE_00840 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_00841 7.9e-157 aatB ET ABC transporter substrate-binding protein
DIGBIBDE_00842 1.5e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIGBIBDE_00843 1.4e-49
DIGBIBDE_00844 6e-45
DIGBIBDE_00845 3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
DIGBIBDE_00846 1.7e-102 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DIGBIBDE_00847 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DIGBIBDE_00848 1e-125 gntR1 K transcriptional
DIGBIBDE_00849 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DIGBIBDE_00850 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DIGBIBDE_00851 2.7e-86
DIGBIBDE_00852 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
DIGBIBDE_00853 4e-127 K DNA-binding helix-turn-helix protein
DIGBIBDE_00854 1e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DIGBIBDE_00855 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIGBIBDE_00856 9.7e-161 GK ROK family
DIGBIBDE_00857 2.5e-155 dprA LU DNA protecting protein DprA
DIGBIBDE_00858 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIGBIBDE_00859 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
DIGBIBDE_00860 1.3e-51 V ABC-2 family transporter protein
DIGBIBDE_00862 2e-149 S TraX protein
DIGBIBDE_00863 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_00864 4.7e-236 T PhoQ Sensor
DIGBIBDE_00865 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DIGBIBDE_00866 2.7e-224 XK27_05470 E Methionine synthase
DIGBIBDE_00867 2e-37 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DIGBIBDE_00868 2.5e-253 V Glucan-binding protein C
DIGBIBDE_00869 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DIGBIBDE_00870 1.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DIGBIBDE_00871 5.5e-95 S Protein of unknown function (DUF1697)
DIGBIBDE_00872 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DIGBIBDE_00873 2.3e-181 clcA_2 P Chloride transporter, ClC family
DIGBIBDE_00874 2.9e-136 yfeJ 6.3.5.2 F glutamine amidotransferase
DIGBIBDE_00875 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
DIGBIBDE_00876 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
DIGBIBDE_00878 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DIGBIBDE_00881 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DIGBIBDE_00882 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
DIGBIBDE_00883 1.2e-41 C Pyridoxamine 5'-phosphate oxidase
DIGBIBDE_00884 8.5e-40 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
DIGBIBDE_00885 5.4e-70 ymdB S Macro domain protein
DIGBIBDE_00886 6.2e-68 mgrA K Transcriptional regulator, MarR family
DIGBIBDE_00887 2.4e-145 1.6.5.2 GM NmrA-like family
DIGBIBDE_00888 2.7e-129 proV E abc transporter atp-binding protein
DIGBIBDE_00889 8.6e-263 proWX P ABC transporter
DIGBIBDE_00890 1.1e-107 magIII L Base excision DNA repair protein, HhH-GPD family
DIGBIBDE_00891 2.3e-32 L Integrase core domain protein
DIGBIBDE_00892 0.0 V ABC transporter (Permease
DIGBIBDE_00893 5.2e-122 V abc transporter atp-binding protein
DIGBIBDE_00894 6.3e-91 tetR K transcriptional regulator
DIGBIBDE_00895 4.4e-141 S Phenazine biosynthesis protein
DIGBIBDE_00896 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
DIGBIBDE_00897 1.3e-132 cbiQ P Cobalt transport protein
DIGBIBDE_00898 5.9e-157 P abc transporter atp-binding protein
DIGBIBDE_00899 9.7e-149 cbiO2 P 'abc transporter, ATP-binding protein
DIGBIBDE_00900 2.3e-113 tnp L DDE domain
DIGBIBDE_00901 5.8e-29 pnuC H Nicotinamide mononucleotide transporter
DIGBIBDE_00902 1.8e-11
DIGBIBDE_00903 4.5e-82 K Transcriptional regulator, TetR family
DIGBIBDE_00904 2e-150 czcD P cation diffusion facilitator family transporter
DIGBIBDE_00905 1.1e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DIGBIBDE_00906 2.8e-188 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
DIGBIBDE_00907 1e-94 L PFAM Integrase catalytic region
DIGBIBDE_00908 2.5e-65 copY K Copper transport repressor, CopY TcrY family
DIGBIBDE_00909 3.7e-66 silP 1.9.3.1, 3.6.3.54 S cog cog4633
DIGBIBDE_00910 0.0 copA 3.6.3.54 P P-type ATPase
DIGBIBDE_00911 3.1e-12 spxB 1.2.3.3, 1.2.5.1 C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
DIGBIBDE_00912 1.2e-147 G protein with an alpha beta hydrolase fold
DIGBIBDE_00913 1.9e-127 ybhF_2 V abc transporter atp-binding protein
DIGBIBDE_00914 3.3e-176 ybhR V ABC-2 family transporter protein
DIGBIBDE_00915 4.5e-109 K Bacterial regulatory proteins, tetR family
DIGBIBDE_00916 2.4e-136 2.4.2.3 F Phosphorylase superfamily
DIGBIBDE_00917 1.3e-108 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
DIGBIBDE_00918 0.0 V Type III restriction enzyme, res subunit
DIGBIBDE_00919 3.7e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
DIGBIBDE_00920 1.3e-235 dinF V Mate efflux family protein
DIGBIBDE_00921 1.9e-270 S Psort location CytoplasmicMembrane, score
DIGBIBDE_00922 3.4e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
DIGBIBDE_00923 1.8e-142 S TraX protein
DIGBIBDE_00924 2e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
DIGBIBDE_00925 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DIGBIBDE_00926 2.2e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DIGBIBDE_00927 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DIGBIBDE_00928 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DIGBIBDE_00929 6.7e-241 nylA 3.5.1.4 J Belongs to the amidase family
DIGBIBDE_00930 4.6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
DIGBIBDE_00931 2.1e-80 yecS P ABC transporter (Permease
DIGBIBDE_00932 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
DIGBIBDE_00933 1e-168 bglC K Transcriptional regulator
DIGBIBDE_00934 5.8e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DIGBIBDE_00935 4.2e-237 agcS E (Alanine) symporter
DIGBIBDE_00936 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DIGBIBDE_00937 3.9e-240 metY 2.5.1.49 E o-acetylhomoserine
DIGBIBDE_00938 1.4e-136 S haloacid dehalogenase-like hydrolase
DIGBIBDE_00939 1.2e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DIGBIBDE_00940 8.1e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
DIGBIBDE_00941 1.8e-34 M1-755 P Hemerythrin HHE cation binding domain protein
DIGBIBDE_00942 6.1e-236 XK27_04775 S hemerythrin HHE cation binding domain
DIGBIBDE_00943 3.6e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIGBIBDE_00944 1.5e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DIGBIBDE_00945 6e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DIGBIBDE_00946 1e-44 yktA S Belongs to the UPF0223 family
DIGBIBDE_00947 3.6e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DIGBIBDE_00948 1.5e-244 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DIGBIBDE_00949 2.6e-155 pstS P phosphate
DIGBIBDE_00950 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
DIGBIBDE_00951 1.3e-154 pstA P phosphate transport system permease
DIGBIBDE_00952 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DIGBIBDE_00953 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DIGBIBDE_00954 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
DIGBIBDE_00955 0.0 pepN 3.4.11.2 E aminopeptidase
DIGBIBDE_00956 1.7e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
DIGBIBDE_00957 2.7e-185 lplA 6.3.1.20 H Lipoate-protein ligase
DIGBIBDE_00958 4.2e-39
DIGBIBDE_00959 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DIGBIBDE_00960 6.9e-297 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
DIGBIBDE_00961 1.6e-169 malR K Transcriptional regulator
DIGBIBDE_00962 2.5e-228 malX G ABC transporter
DIGBIBDE_00963 7.4e-250 malF P ABC transporter (Permease
DIGBIBDE_00964 9.8e-152 malG P ABC transporter (Permease
DIGBIBDE_00965 4.7e-213 msmX P Belongs to the ABC transporter superfamily
DIGBIBDE_00967 3e-24 tatA U protein secretion
DIGBIBDE_00968 2.4e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIGBIBDE_00969 1.1e-287 ywbL P COG0672 High-affinity Fe2 Pb2 permease
DIGBIBDE_00970 1.6e-232 ycdB P peroxidase
DIGBIBDE_00971 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
DIGBIBDE_00972 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DIGBIBDE_00973 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DIGBIBDE_00974 0.0 lpdA 1.8.1.4 C Dehydrogenase
DIGBIBDE_00975 2.2e-217 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DIGBIBDE_00976 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DIGBIBDE_00977 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DIGBIBDE_00978 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_00979 1.1e-234 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_00980 0.0 S the current gene model (or a revised gene model) may contain a frame shift
DIGBIBDE_00981 7.5e-236 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DIGBIBDE_00982 3.8e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIGBIBDE_00983 1.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DIGBIBDE_00984 1.8e-251 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
DIGBIBDE_00985 6.1e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
DIGBIBDE_00986 2.7e-157 rssA S Phospholipase, patatin family
DIGBIBDE_00987 1.8e-102 estA E Lysophospholipase L1 and related esterases
DIGBIBDE_00988 1.7e-282 S unusual protein kinase
DIGBIBDE_00989 4.1e-38 S granule-associated protein
DIGBIBDE_00990 5.4e-283 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DIGBIBDE_00991 2.6e-195 S hmm pf01594
DIGBIBDE_00992 9e-107 G Belongs to the phosphoglycerate mutase family
DIGBIBDE_00993 1.7e-108 G Belongs to the phosphoglycerate mutase family
DIGBIBDE_00994 2.8e-108 pgm G Belongs to the phosphoglycerate mutase family
DIGBIBDE_00995 6.4e-148 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DIGBIBDE_00996 5.5e-243 S Polysaccharide biosynthesis protein
DIGBIBDE_00997 0.0 M Polysaccharide biosynthesis protein
DIGBIBDE_00998 1.3e-204 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DIGBIBDE_00999 2.7e-171 S glycosyl transferase family 2
DIGBIBDE_01000 4e-85
DIGBIBDE_01001 4.4e-205 M glycosyl transferase group 1
DIGBIBDE_01002 2e-163 S Glycosyl transferase family 2
DIGBIBDE_01003 7.4e-160 licD M LICD family
DIGBIBDE_01004 6.3e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DIGBIBDE_01005 2.8e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DIGBIBDE_01006 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
DIGBIBDE_01007 1e-114 cps4C M biosynthesis protein
DIGBIBDE_01008 5.2e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
DIGBIBDE_01009 1.4e-238 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
DIGBIBDE_01010 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
DIGBIBDE_01011 3.6e-271 pepV 3.5.1.18 E Dipeptidase
DIGBIBDE_01012 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DIGBIBDE_01013 1.9e-92 yybC
DIGBIBDE_01014 4.5e-76 XK27_03610 K Gnat family
DIGBIBDE_01015 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DIGBIBDE_01016 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DIGBIBDE_01017 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DIGBIBDE_01018 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DIGBIBDE_01019 2.4e-17 M LysM domain
DIGBIBDE_01020 5.1e-87 ebsA S Family of unknown function (DUF5322)
DIGBIBDE_01021 1.3e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DIGBIBDE_01022 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
DIGBIBDE_01023 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DIGBIBDE_01024 2.3e-221 G COG0457 FOG TPR repeat
DIGBIBDE_01025 4e-175 yubA S permease
DIGBIBDE_01026 3.1e-89 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
DIGBIBDE_01027 1.2e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DIGBIBDE_01028 3.2e-124 ftsE D cell division ATP-binding protein FtsE
DIGBIBDE_01029 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DIGBIBDE_01030 1.7e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DIGBIBDE_01031 1.1e-155 yjjH S Calcineurin-like phosphoesterase
DIGBIBDE_01032 7.7e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DIGBIBDE_01033 0.0 pacL 3.6.3.8 P cation transport ATPase
DIGBIBDE_01034 5.3e-68 ywiB S Domain of unknown function (DUF1934)
DIGBIBDE_01035 1.3e-108 XK27_00120 2.4.2.3 F Phosphorylase superfamily
DIGBIBDE_01036 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
DIGBIBDE_01037 2e-146 yidA S hydrolases of the HAD superfamily
DIGBIBDE_01038 1.6e-206 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
DIGBIBDE_01039 1.3e-57 S Protein of unknown function (DUF454)
DIGBIBDE_01040 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
DIGBIBDE_01041 1e-235 vicK 2.7.13.3 T Histidine kinase
DIGBIBDE_01042 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DIGBIBDE_01043 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_01044 1.9e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DIGBIBDE_01045 7.9e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_01046 4.9e-143 peb1A ET Belongs to the bacterial solute-binding protein 3 family
DIGBIBDE_01047 1.9e-116 gltJ P ABC transporter (Permease
DIGBIBDE_01048 1.1e-110 tcyB_2 P ABC transporter (permease)
DIGBIBDE_01049 6.5e-154 endA F DNA RNA non-specific endonuclease
DIGBIBDE_01050 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
DIGBIBDE_01051 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIGBIBDE_01053 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
DIGBIBDE_01054 2.1e-249 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
DIGBIBDE_01056 2.9e-137
DIGBIBDE_01057 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DIGBIBDE_01058 2.4e-76 L Transposase (IS116 IS110 IS902 family)
DIGBIBDE_01059 2.7e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DIGBIBDE_01060 3.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DIGBIBDE_01061 2.6e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIGBIBDE_01062 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
DIGBIBDE_01063 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DIGBIBDE_01064 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
DIGBIBDE_01065 6.6e-08
DIGBIBDE_01066 5.6e-132 K cell adhesion
DIGBIBDE_01068 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DIGBIBDE_01069 1.5e-212 XK27_05110 P Chloride transporter ClC family
DIGBIBDE_01070 2.5e-27 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
DIGBIBDE_01071 9.2e-281 clcA P Chloride transporter, ClC family
DIGBIBDE_01072 1e-75 fld C Flavodoxin
DIGBIBDE_01073 7.5e-19 XK27_08880
DIGBIBDE_01074 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
DIGBIBDE_01075 2.3e-147 estA CE1 S Esterase
DIGBIBDE_01076 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIGBIBDE_01077 6.8e-136 XK27_08845 S abc transporter atp-binding protein
DIGBIBDE_01078 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
DIGBIBDE_01079 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
DIGBIBDE_01080 6.4e-18 S Domain of unknown function (DUF4649)
DIGBIBDE_01081 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DIGBIBDE_01082 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DIGBIBDE_01083 0.0 dnaE 2.7.7.7 L DNA polymerase
DIGBIBDE_01084 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DIGBIBDE_01085 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DIGBIBDE_01086 3.5e-37 ysdA L Membrane
DIGBIBDE_01087 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DIGBIBDE_01088 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIGBIBDE_01089 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIGBIBDE_01090 1.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
DIGBIBDE_01092 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DIGBIBDE_01093 2.9e-94 ypmS S Protein conserved in bacteria
DIGBIBDE_01094 6.9e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
DIGBIBDE_01095 1.3e-143 DegV S DegV family
DIGBIBDE_01096 3.9e-301 recN L May be involved in recombinational repair of damaged DNA
DIGBIBDE_01097 8.3e-73 argR K Regulates arginine biosynthesis genes
DIGBIBDE_01098 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DIGBIBDE_01099 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DIGBIBDE_01100 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DIGBIBDE_01101 3.6e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DIGBIBDE_01103 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DIGBIBDE_01104 1.3e-125 dnaD
DIGBIBDE_01105 1.5e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIGBIBDE_01106 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIGBIBDE_01107 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
DIGBIBDE_01108 6.1e-67 GnaT 2.5.1.16 K acetyltransferase
DIGBIBDE_01109 1.5e-33 Q Methyltransferase domain
DIGBIBDE_01110 6.3e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DIGBIBDE_01111 4.6e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DIGBIBDE_01112 5.8e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DIGBIBDE_01113 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIGBIBDE_01114 1.5e-237 rodA D Belongs to the SEDS family
DIGBIBDE_01115 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_01116 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_01117 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
DIGBIBDE_01118 1.9e-181 XK27_08075 M glycosyl transferase family 2
DIGBIBDE_01119 1.2e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
DIGBIBDE_01120 2.8e-42 P molecular chaperone
DIGBIBDE_01121 4.1e-95 P molecular chaperone
DIGBIBDE_01122 5.5e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
DIGBIBDE_01123 1.9e-88 L COG1943 Transposase and inactivated derivatives
DIGBIBDE_01126 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
DIGBIBDE_01127 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DIGBIBDE_01128 1.4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DIGBIBDE_01129 4.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DIGBIBDE_01130 6.8e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DIGBIBDE_01131 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DIGBIBDE_01132 2.1e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DIGBIBDE_01133 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DIGBIBDE_01134 5e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DIGBIBDE_01135 1.4e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DIGBIBDE_01136 4e-63 XK27_08085
DIGBIBDE_01137 1.2e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
DIGBIBDE_01138 3.2e-70
DIGBIBDE_01139 8.5e-12
DIGBIBDE_01140 2.8e-219 V MatE
DIGBIBDE_01141 5.2e-53 S Coenzyme PQQ synthesis protein D (PqqD)
DIGBIBDE_01142 1.1e-222 C Fe-S oxidoreductases
DIGBIBDE_01143 1.3e-179 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DIGBIBDE_01144 1.3e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
DIGBIBDE_01145 4.6e-117 ylfI S tigr01906
DIGBIBDE_01146 2.3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DIGBIBDE_01147 9.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
DIGBIBDE_01148 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
DIGBIBDE_01149 8.4e-30 KT response to antibiotic
DIGBIBDE_01151 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DIGBIBDE_01152 2.1e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DIGBIBDE_01153 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DIGBIBDE_01154 4.3e-258 S phospholipase Carboxylesterase
DIGBIBDE_01155 2.2e-196 yurR 1.4.5.1 E oxidoreductase
DIGBIBDE_01156 7.2e-110 zupT P Mediates zinc uptake. May also transport other divalent cations
DIGBIBDE_01157 1.5e-23 zupT P Mediates zinc uptake. May also transport other divalent cations
DIGBIBDE_01158 3.9e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIGBIBDE_01159 7.4e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
DIGBIBDE_01160 1.8e-66 gtrA S GtrA-like protein
DIGBIBDE_01161 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIGBIBDE_01162 6e-169 ybbR S Protein conserved in bacteria
DIGBIBDE_01163 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DIGBIBDE_01164 7.6e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
DIGBIBDE_01165 1.9e-149 cobQ S glutamine amidotransferase
DIGBIBDE_01166 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DIGBIBDE_01167 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
DIGBIBDE_01168 3.5e-39 MA20_06245 S yiaA/B two helix domain
DIGBIBDE_01169 0.0 uup S abc transporter atp-binding protein
DIGBIBDE_01170 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
DIGBIBDE_01171 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
DIGBIBDE_01172 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
DIGBIBDE_01173 2.7e-153 XK27_05675 S Esterase
DIGBIBDE_01174 6.1e-162 XK27_05670 S Putative esterase
DIGBIBDE_01175 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
DIGBIBDE_01176 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIGBIBDE_01177 3e-38 ptsH G phosphocarrier protein Hpr
DIGBIBDE_01178 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
DIGBIBDE_01179 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
DIGBIBDE_01180 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DIGBIBDE_01181 6.5e-34 nrdH O Glutaredoxin
DIGBIBDE_01182 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIGBIBDE_01183 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIGBIBDE_01184 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIGBIBDE_01185 3.5e-136 divIVA D Cell division initiation protein
DIGBIBDE_01186 2.7e-143 ylmH S conserved protein, contains S4-like domain
DIGBIBDE_01187 2.9e-30 yggT D integral membrane protein
DIGBIBDE_01188 1.8e-99 sepF D cell septum assembly
DIGBIBDE_01189 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DIGBIBDE_01190 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DIGBIBDE_01191 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DIGBIBDE_01192 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DIGBIBDE_01193 4.7e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIGBIBDE_01194 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIGBIBDE_01196 0.0 typA T GTP-binding protein TypA
DIGBIBDE_01197 2.4e-178 glk 2.7.1.2 G Glucokinase
DIGBIBDE_01198 2.4e-27 yqgQ S protein conserved in bacteria
DIGBIBDE_01199 3.8e-81 perR P Belongs to the Fur family
DIGBIBDE_01200 9.3e-92 dps P Belongs to the Dps family
DIGBIBDE_01201 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
DIGBIBDE_01202 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
DIGBIBDE_01203 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
DIGBIBDE_01204 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
DIGBIBDE_01205 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DIGBIBDE_01206 2e-62 S Domain of unknown function (DUF4430)
DIGBIBDE_01207 6.7e-73 S Psort location CytoplasmicMembrane, score
DIGBIBDE_01208 1.1e-125 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
DIGBIBDE_01209 1.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
DIGBIBDE_01210 1.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
DIGBIBDE_01211 1.1e-118 sirR K iron dependent repressor
DIGBIBDE_01212 1.5e-134 htpX O Belongs to the peptidase M48B family
DIGBIBDE_01213 1.5e-92 lemA S LemA family
DIGBIBDE_01214 4.2e-173 spd F DNA RNA non-specific endonuclease
DIGBIBDE_01215 0.0 2.4.1.21 GT5 M Right handed beta helix region
DIGBIBDE_01216 1.3e-07 S double-stranded DNA endodeoxyribonuclease activity
DIGBIBDE_01217 1.3e-136 S double-stranded DNA endodeoxyribonuclease activity
DIGBIBDE_01218 9.9e-302 hsdM 2.1.1.72 V type I restriction-modification system
DIGBIBDE_01219 1e-42 K Helix-turn-helix domain
DIGBIBDE_01220 9.8e-56 S Phage derived protein Gp49-like (DUF891)
DIGBIBDE_01221 2e-92 3.1.21.3 V Type I restriction modification DNA specificity domain
DIGBIBDE_01222 3.8e-73 T Pfam Adenylate and Guanylate cyclase catalytic domain
DIGBIBDE_01223 1.4e-36 immA E Zn peptidase
DIGBIBDE_01225 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DIGBIBDE_01226 4.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DIGBIBDE_01227 1.5e-214 MA20_36090 S Protein of unknown function (DUF2974)
DIGBIBDE_01228 1.8e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIGBIBDE_01229 1.7e-159 5.2.1.8 G hydrolase
DIGBIBDE_01230 5.3e-27 P Hemerythrin HHE cation binding domain protein
DIGBIBDE_01231 5.8e-142 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
DIGBIBDE_01232 6.1e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DIGBIBDE_01233 6e-117 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
DIGBIBDE_01234 5.2e-175 S hydrolase
DIGBIBDE_01235 8.4e-23
DIGBIBDE_01236 6.7e-152 M LysM domain
DIGBIBDE_01237 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DIGBIBDE_01239 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
DIGBIBDE_01240 1.8e-33 XK27_12190 S protein conserved in bacteria
DIGBIBDE_01242 1e-88 bioY S biotin synthase
DIGBIBDE_01243 1.3e-251 yegQ O Peptidase U32
DIGBIBDE_01244 6.8e-178 yegQ O Peptidase U32
DIGBIBDE_01246 1.2e-68 ytxH S General stress protein
DIGBIBDE_01247 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DIGBIBDE_01248 9.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIGBIBDE_01249 8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DIGBIBDE_01250 2.2e-41 pspC KT PspC domain
DIGBIBDE_01251 0.0 yhgF K Transcriptional accessory protein
DIGBIBDE_01253 6e-155 XK27_03015 S permease
DIGBIBDE_01254 8.4e-148 ycgQ S TIGR03943 family
DIGBIBDE_01255 2.1e-278 sulP P Sulfate permease and related transporters (MFS superfamily)
DIGBIBDE_01256 4.7e-103
DIGBIBDE_01257 1.8e-113 estA E GDSL-like Lipase/Acylhydrolase
DIGBIBDE_01258 2.6e-93 S CAAX protease self-immunity
DIGBIBDE_01259 6.1e-50
DIGBIBDE_01261 4.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
DIGBIBDE_01262 1.9e-60 S Protein of unknown function (DUF1722)
DIGBIBDE_01263 4.5e-20 S Bacterial lipoprotein
DIGBIBDE_01264 1.3e-09
DIGBIBDE_01265 1e-128 V CAAX protease self-immunity
DIGBIBDE_01266 7.9e-46
DIGBIBDE_01267 2.7e-76 K TetR family transcriptional regulator
DIGBIBDE_01268 7.6e-82 Q Methyltransferase domain
DIGBIBDE_01269 2.8e-120 ybbA S Putative esterase
DIGBIBDE_01270 1.6e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
DIGBIBDE_01271 5.8e-135 fecE 3.6.3.34 HP ABC transporter
DIGBIBDE_01272 1e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIGBIBDE_01273 3.2e-117 V CAAX protease self-immunity
DIGBIBDE_01274 5.1e-148 S Domain of unknown function (DUF4300)
DIGBIBDE_01275 6.3e-91 tetR K transcriptional regulator
DIGBIBDE_01276 4e-280 norB P Major facilitator superfamily
DIGBIBDE_01277 3.2e-21 S Domain of unknown function (DUF4767)
DIGBIBDE_01279 4.1e-110 cutC P Participates in the control of copper homeostasis
DIGBIBDE_01280 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
DIGBIBDE_01281 1.3e-148 yitS S EDD domain protein, DegV family
DIGBIBDE_01282 6.5e-202 yeaN P transporter
DIGBIBDE_01283 4.8e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
DIGBIBDE_01284 1.4e-139 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DIGBIBDE_01286 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DIGBIBDE_01287 1.7e-60 smtB K Transcriptional regulator
DIGBIBDE_01288 9.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
DIGBIBDE_01289 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
DIGBIBDE_01290 5.5e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIGBIBDE_01291 2e-97 mip S hydroperoxide reductase activity
DIGBIBDE_01292 2.2e-201 I acyl-CoA dehydrogenase
DIGBIBDE_01293 5.5e-143 ydiA P C4-dicarboxylate transporter malic acid transport protein
DIGBIBDE_01294 2.7e-242 msrR K Transcriptional regulator
DIGBIBDE_01295 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
DIGBIBDE_01296 2.1e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DIGBIBDE_01297 1e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DIGBIBDE_01298 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DIGBIBDE_01299 1.2e-52 yheA S Belongs to the UPF0342 family
DIGBIBDE_01300 6.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
DIGBIBDE_01301 1.7e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DIGBIBDE_01302 8.6e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIGBIBDE_01303 1.3e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DIGBIBDE_01304 5.4e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DIGBIBDE_01305 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
DIGBIBDE_01306 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DIGBIBDE_01307 1.3e-24 WQ51_00785
DIGBIBDE_01309 4.2e-09
DIGBIBDE_01311 3.1e-133 S peptidoglycan catabolic process
DIGBIBDE_01312 4.9e-29 hol S Holin, phage phi LC3 family
DIGBIBDE_01315 1.7e-07
DIGBIBDE_01316 1.8e-59 S Pfam:Phage_holin_4_1
DIGBIBDE_01317 1.4e-11
DIGBIBDE_01318 2.7e-267
DIGBIBDE_01319 0.0 S peptidoglycan catabolic process
DIGBIBDE_01320 8.6e-178 S Phage tail protein
DIGBIBDE_01321 7.5e-185 S peptidoglycan catabolic process
DIGBIBDE_01323 2e-40 S Pfam:Phage_TAC_12
DIGBIBDE_01324 4.2e-73 S Phage major tail protein 2
DIGBIBDE_01325 4.5e-54
DIGBIBDE_01326 2.8e-36 S exonuclease activity
DIGBIBDE_01328 3.8e-36 S Phage gp6-like head-tail connector protein
DIGBIBDE_01330 4.1e-147 S Phage major capsid protein E
DIGBIBDE_01331 5.9e-16
DIGBIBDE_01332 1.6e-23 S Domain of unknown function (DUF4355)
DIGBIBDE_01334 2.2e-134 S Phage Mu protein F like protein
DIGBIBDE_01335 6.6e-223 S Phage portal protein, SPP1 Gp6-like
DIGBIBDE_01336 4.1e-104 S Terminase-like family
DIGBIBDE_01337 1.5e-12 S nucleic acid binding
DIGBIBDE_01338 8.5e-122 S Terminase-like family
DIGBIBDE_01339 6.5e-34 L DNA packaging
DIGBIBDE_01340 2.3e-21 N HicA toxin of bacterial toxin-antitoxin,
DIGBIBDE_01341 7e-49 S HicB_like antitoxin of bacterial toxin-antitoxin system
DIGBIBDE_01342 3.3e-31
DIGBIBDE_01346 6.8e-15 S YopX protein
DIGBIBDE_01348 1.3e-58 S sequence-specific DNA binding
DIGBIBDE_01349 2.8e-32 S Protein of unknown function (DUF1642)
DIGBIBDE_01351 5.6e-33 S magnesium ion binding
DIGBIBDE_01352 1.7e-66 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DIGBIBDE_01353 2.7e-52 S Protein of unknown function (DUF1351)
DIGBIBDE_01354 4.8e-35 S ERF superfamily
DIGBIBDE_01357 4.8e-26 pac D Glucan-binding protein C
DIGBIBDE_01359 9e-33
DIGBIBDE_01360 2.2e-24
DIGBIBDE_01361 1.8e-08 S ORF6C domain
DIGBIBDE_01362 1.4e-85
DIGBIBDE_01367 1.6e-17 K Cro/C1-type HTH DNA-binding domain
DIGBIBDE_01368 1.8e-16
DIGBIBDE_01370 7e-72 K Peptidase S24-like
DIGBIBDE_01371 1e-23
DIGBIBDE_01374 6.9e-204 S Phage integrase family
DIGBIBDE_01375 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DIGBIBDE_01376 3.1e-75 yueI S Protein of unknown function (DUF1694)
DIGBIBDE_01377 9e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DIGBIBDE_01378 5e-193 yyaQ S YjbR
DIGBIBDE_01379 1.9e-181 ccpA K Catabolite control protein A
DIGBIBDE_01380 3.8e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
DIGBIBDE_01381 2.4e-62 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
DIGBIBDE_01382 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIGBIBDE_01383 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DIGBIBDE_01384 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DIGBIBDE_01385 2e-33 secG U Preprotein translocase subunit SecG
DIGBIBDE_01386 2.7e-222 mdtG EGP Major facilitator Superfamily
DIGBIBDE_01387 5.6e-93 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DIGBIBDE_01388 5.7e-144 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DIGBIBDE_01389 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIGBIBDE_01390 5.8e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DIGBIBDE_01391 5e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DIGBIBDE_01392 4.7e-46 licT K antiterminator
DIGBIBDE_01393 1.8e-76 licT K antiterminator
DIGBIBDE_01394 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DIGBIBDE_01395 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
DIGBIBDE_01396 1.5e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DIGBIBDE_01397 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DIGBIBDE_01398 1.3e-150 I Alpha/beta hydrolase family
DIGBIBDE_01399 6.6e-08
DIGBIBDE_01400 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DIGBIBDE_01401 1.4e-78 feoA P FeoA domain protein
DIGBIBDE_01402 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_01403 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
DIGBIBDE_01404 1e-34 ykuJ S protein conserved in bacteria
DIGBIBDE_01405 1.4e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DIGBIBDE_01406 0.0 clpE O Belongs to the ClpA ClpB family
DIGBIBDE_01407 6.3e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
DIGBIBDE_01408 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
DIGBIBDE_01409 2.4e-170 S oxidoreductase
DIGBIBDE_01410 3.9e-229 murN 2.3.2.16 V FemAB family
DIGBIBDE_01411 4.4e-118 M Pfam SNARE associated Golgi protein
DIGBIBDE_01412 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
DIGBIBDE_01415 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
DIGBIBDE_01418 4.8e-16 S Protein of unknown function (DUF2969)
DIGBIBDE_01419 2.6e-199 ilvE 2.6.1.42 E Aminotransferase
DIGBIBDE_01420 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DIGBIBDE_01421 2.4e-10
DIGBIBDE_01423 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DIGBIBDE_01424 1.3e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DIGBIBDE_01425 2.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
DIGBIBDE_01426 2.2e-30 S Domain of unknown function (DUF1912)
DIGBIBDE_01427 1.6e-174 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
DIGBIBDE_01428 6.8e-251 mmuP E amino acid
DIGBIBDE_01429 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
DIGBIBDE_01430 1.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DIGBIBDE_01431 9.7e-22
DIGBIBDE_01432 1.2e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIGBIBDE_01433 5.9e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DIGBIBDE_01434 7.9e-216 mvaS 2.3.3.10 I synthase
DIGBIBDE_01435 3e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DIGBIBDE_01436 8.6e-78 K hmm pf08876
DIGBIBDE_01437 5.2e-119 yqfA K protein, Hemolysin III
DIGBIBDE_01438 4.1e-29 pspC KT PspC domain protein
DIGBIBDE_01439 4.4e-197 S Protein of unknown function (DUF3114)
DIGBIBDE_01440 3.2e-159 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DIGBIBDE_01441 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIGBIBDE_01442 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DIGBIBDE_01443 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
DIGBIBDE_01444 0.0 U protein secretion
DIGBIBDE_01445 1.2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIGBIBDE_01446 2e-26
DIGBIBDE_01447 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
DIGBIBDE_01448 1.2e-255 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DIGBIBDE_01449 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DIGBIBDE_01451 2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DIGBIBDE_01452 1.5e-162 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DIGBIBDE_01453 4.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DIGBIBDE_01454 1.5e-134 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DIGBIBDE_01455 8.2e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIGBIBDE_01456 2.1e-89 E Alpha beta hydrolase
DIGBIBDE_01459 1.3e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
DIGBIBDE_01460 9.1e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DIGBIBDE_01461 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DIGBIBDE_01462 5.1e-114 S VIT family
DIGBIBDE_01463 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
DIGBIBDE_01464 1.3e-21
DIGBIBDE_01465 2.7e-28 XK27_00085 K Transcriptional
DIGBIBDE_01466 5.3e-197 yceA S Belongs to the UPF0176 family
DIGBIBDE_01467 3.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DIGBIBDE_01468 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DIGBIBDE_01469 0.0 lmrA V abc transporter atp-binding protein
DIGBIBDE_01470 0.0 mdlB V abc transporter atp-binding protein
DIGBIBDE_01471 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
DIGBIBDE_01473 9.2e-228 L DNA integration
DIGBIBDE_01474 2.4e-16 S Domain of unknown function (DUF3173)
DIGBIBDE_01475 4e-71
DIGBIBDE_01476 9.8e-261 D ftsk spoiiie
DIGBIBDE_01480 0.0 2.1.1.72 V DNA modification
DIGBIBDE_01481 6.7e-44 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DIGBIBDE_01482 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DIGBIBDE_01483 1.2e-211 V permease protein
DIGBIBDE_01484 2.9e-120 macB V ABC transporter, ATP-binding protein
DIGBIBDE_01485 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIGBIBDE_01486 6.4e-126 2.1.1.223 S Putative SAM-dependent methyltransferase
DIGBIBDE_01487 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
DIGBIBDE_01488 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
DIGBIBDE_01489 1.7e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DIGBIBDE_01490 1.8e-221 pyrP F uracil Permease
DIGBIBDE_01491 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIGBIBDE_01492 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DIGBIBDE_01493 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIGBIBDE_01494 4.7e-168 fhuR K transcriptional regulator (lysR family)
DIGBIBDE_01496 5.1e-73 K Helix-turn-helix
DIGBIBDE_01498 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIGBIBDE_01499 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
DIGBIBDE_01500 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
DIGBIBDE_01501 6.7e-254 cycA E permease
DIGBIBDE_01502 3.8e-38 ynzC S UPF0291 protein
DIGBIBDE_01503 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DIGBIBDE_01504 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DIGBIBDE_01505 9.6e-220 S membrane
DIGBIBDE_01506 3e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DIGBIBDE_01507 1.7e-293 nptA P COG1283 Na phosphate symporter
DIGBIBDE_01508 2.8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
DIGBIBDE_01509 5.4e-76 S Bacterial inner membrane protein
DIGBIBDE_01510 1.8e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
DIGBIBDE_01511 1.7e-108 S HD domain
DIGBIBDE_01512 2.1e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
DIGBIBDE_01513 1.9e-53 glnB K Belongs to the P(II) protein family
DIGBIBDE_01514 3.1e-226 amt P Ammonium Transporter
DIGBIBDE_01515 1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DIGBIBDE_01516 1.2e-54 yabA L Involved in initiation control of chromosome replication
DIGBIBDE_01517 1.3e-132 yaaT S stage 0 sporulation protein
DIGBIBDE_01518 5.1e-159 holB 2.7.7.7 L dna polymerase iii
DIGBIBDE_01519 3.8e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DIGBIBDE_01521 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DIGBIBDE_01522 1.3e-134 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DIGBIBDE_01523 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIGBIBDE_01524 1e-216 ftsW D Belongs to the SEDS family
DIGBIBDE_01525 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DIGBIBDE_01526 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DIGBIBDE_01527 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DIGBIBDE_01528 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DIGBIBDE_01529 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIGBIBDE_01530 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DIGBIBDE_01531 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
DIGBIBDE_01532 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIGBIBDE_01533 1.3e-26 femA 2.3.2.10, 2.3.2.16 V FemAB family
DIGBIBDE_01534 3.1e-106 femA 2.3.2.10, 2.3.2.16 V FemAB family
DIGBIBDE_01536 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
DIGBIBDE_01537 7e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
DIGBIBDE_01538 6.3e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIGBIBDE_01539 1e-104 wecD M Acetyltransferase (GNAT) domain
DIGBIBDE_01540 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DIGBIBDE_01541 4.7e-160 GK ROK family
DIGBIBDE_01542 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
DIGBIBDE_01543 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
DIGBIBDE_01544 4.4e-205 potD P spermidine putrescine ABC transporter
DIGBIBDE_01545 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
DIGBIBDE_01546 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
DIGBIBDE_01547 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DIGBIBDE_01548 7.3e-169 murB 1.3.1.98 M cell wall formation
DIGBIBDE_01549 2e-80 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DIGBIBDE_01550 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DIGBIBDE_01551 1.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
DIGBIBDE_01552 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DIGBIBDE_01553 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
DIGBIBDE_01554 0.0 ydaO E amino acid
DIGBIBDE_01555 4.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DIGBIBDE_01556 2.4e-37 ylqC L Belongs to the UPF0109 family
DIGBIBDE_01557 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DIGBIBDE_01560 7.8e-198 2.7.13.3 T GHKL domain
DIGBIBDE_01561 2.1e-129 agrA KT phosphorelay signal transduction system
DIGBIBDE_01562 2.8e-190 O protein import
DIGBIBDE_01563 5.1e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
DIGBIBDE_01564 2.9e-17 yjdB S Domain of unknown function (DUF4767)
DIGBIBDE_01565 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIGBIBDE_01567 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
DIGBIBDE_01568 2.9e-71 S QueT transporter
DIGBIBDE_01570 4.8e-174 yfjR K regulation of single-species biofilm formation
DIGBIBDE_01571 4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DIGBIBDE_01572 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIGBIBDE_01573 8.2e-85 ccl S cog cog4708
DIGBIBDE_01574 3.7e-163 rbn E Belongs to the UPF0761 family
DIGBIBDE_01575 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
DIGBIBDE_01576 1.1e-231 ytoI K transcriptional regulator containing CBS domains
DIGBIBDE_01577 2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
DIGBIBDE_01578 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIGBIBDE_01579 0.0 comEC S Competence protein ComEC
DIGBIBDE_01580 1.1e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
DIGBIBDE_01581 9.8e-143 plsC 2.3.1.51 I Acyltransferase
DIGBIBDE_01582 1.2e-156 nodB3 G deacetylase
DIGBIBDE_01583 5.5e-141 yabB 2.1.1.223 L Methyltransferase
DIGBIBDE_01584 7e-43 yazA L endonuclease containing a URI domain
DIGBIBDE_01585 1.1e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DIGBIBDE_01586 7.4e-153 corA P CorA-like protein
DIGBIBDE_01587 2.5e-62 yjqA S Bacterial PH domain
DIGBIBDE_01588 7.8e-100 thiT S Thiamine transporter
DIGBIBDE_01589 1e-148 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DIGBIBDE_01590 1e-191 yjbB G Permeases of the major facilitator superfamily
DIGBIBDE_01591 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DIGBIBDE_01592 3.1e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
DIGBIBDE_01593 3.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DIGBIBDE_01597 3.3e-155 cjaA ET ABC transporter substrate-binding protein
DIGBIBDE_01598 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_01599 4.3e-105 P ABC transporter (Permease
DIGBIBDE_01600 3.9e-114 papP P ABC transporter (Permease
DIGBIBDE_01601 5.4e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DIGBIBDE_01602 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
DIGBIBDE_01603 0.0 copA 3.6.3.54 P P-type ATPase
DIGBIBDE_01604 6.1e-73 copY K negative regulation of transcription, DNA-templated
DIGBIBDE_01605 1.7e-162 EGP Major facilitator Superfamily
DIGBIBDE_01608 1.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DIGBIBDE_01609 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DIGBIBDE_01610 2.5e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
DIGBIBDE_01611 2.1e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
DIGBIBDE_01612 2.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DIGBIBDE_01613 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
DIGBIBDE_01614 1.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIGBIBDE_01615 2.4e-38 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
DIGBIBDE_01616 3.5e-120 yujD V lipoprotein transporter activity
DIGBIBDE_01617 0.0 S bacteriocin-associated integral membrane protein
DIGBIBDE_01618 2.1e-19 S Bacteriocin (Lactococcin_972)
DIGBIBDE_01619 4.3e-59
DIGBIBDE_01620 0.0 ctpE P E1-E2 ATPase
DIGBIBDE_01621 2.4e-43
DIGBIBDE_01622 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DIGBIBDE_01624 3.9e-125 V abc transporter atp-binding protein
DIGBIBDE_01625 0.0 V ABC transporter (Permease
DIGBIBDE_01626 1.7e-128 K transcriptional regulator, MerR family
DIGBIBDE_01627 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
DIGBIBDE_01628 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
DIGBIBDE_01629 8.2e-63 XK27_02560 S cog cog2151
DIGBIBDE_01630 3.2e-141 L PFAM transposase IS116 IS110 IS902 family
DIGBIBDE_01631 5.5e-65 L Transposase (IS116 IS110 IS902 family)
DIGBIBDE_01632 1e-20 recQ 3.6.4.12 L helicase superfamily c-terminal domain
DIGBIBDE_01633 7.1e-104 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIGBIBDE_01634 5.9e-16
DIGBIBDE_01635 3.2e-83 L COG1943 Transposase and inactivated derivatives
DIGBIBDE_01636 2.9e-122 L Helix-turn-helix domain
DIGBIBDE_01637 3.7e-141 L Integrase core domain protein
DIGBIBDE_01638 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DIGBIBDE_01639 6.3e-221 ytfP S Flavoprotein
DIGBIBDE_01641 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DIGBIBDE_01642 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
DIGBIBDE_01643 1.4e-176 ecsB U Bacterial ABC transporter protein EcsB
DIGBIBDE_01644 9.9e-132 ecsA V abc transporter atp-binding protein
DIGBIBDE_01645 1.7e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DIGBIBDE_01646 7.4e-09
DIGBIBDE_01647 4.7e-57 S CD20-like family
DIGBIBDE_01648 7.9e-53
DIGBIBDE_01650 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
DIGBIBDE_01652 5.1e-43 yoeB S Addiction module toxin, Txe YoeB family
DIGBIBDE_01653 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DIGBIBDE_01654 2.8e-199 ylbM S Belongs to the UPF0348 family
DIGBIBDE_01655 1.3e-139 yqeM Q Methyltransferase domain protein
DIGBIBDE_01656 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DIGBIBDE_01657 1.1e-84 entB 3.5.1.19 Q Isochorismatase family
DIGBIBDE_01658 1.6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
DIGBIBDE_01659 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DIGBIBDE_01660 7.7e-49 yhbY J RNA-binding protein
DIGBIBDE_01661 4.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DIGBIBDE_01662 3.3e-97 yqeG S hydrolase of the HAD superfamily
DIGBIBDE_01663 1.5e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DIGBIBDE_01666 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIGBIBDE_01667 1.3e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DIGBIBDE_01668 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIGBIBDE_01669 6.1e-63 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DIGBIBDE_01670 1.2e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DIGBIBDE_01671 2e-100 pncA Q isochorismatase
DIGBIBDE_01672 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DIGBIBDE_01673 1.5e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
DIGBIBDE_01674 9e-75 XK27_03180 T universal stress protein
DIGBIBDE_01676 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DIGBIBDE_01677 4.3e-10 MU outer membrane autotransporter barrel domain protein
DIGBIBDE_01678 2.1e-236 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
DIGBIBDE_01679 6e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
DIGBIBDE_01680 0.0 yjcE P NhaP-type Na H and K H antiporters
DIGBIBDE_01682 1.6e-94 ytqB J (SAM)-dependent
DIGBIBDE_01683 5.4e-183 yhcC S radical SAM protein
DIGBIBDE_01684 2.1e-186 ylbL T Belongs to the peptidase S16 family
DIGBIBDE_01685 1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DIGBIBDE_01686 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
DIGBIBDE_01687 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DIGBIBDE_01688 5e-10 S Protein of unknown function (DUF4059)
DIGBIBDE_01689 7.2e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
DIGBIBDE_01690 1.4e-162 yxeN P ABC transporter (Permease
DIGBIBDE_01691 1.6e-14 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DIGBIBDE_01692 1.7e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DIGBIBDE_01693 1e-34
DIGBIBDE_01694 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIGBIBDE_01695 0.0 pflB 2.3.1.54 C formate acetyltransferase'
DIGBIBDE_01697 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
DIGBIBDE_01698 4.7e-148 cah 4.2.1.1 P carbonic anhydrase
DIGBIBDE_01699 4.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DIGBIBDE_01701 4.8e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
DIGBIBDE_01702 3.2e-141 cppA E CppA N-terminal
DIGBIBDE_01703 1.5e-97 V CAAX protease self-immunity
DIGBIBDE_01704 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DIGBIBDE_01705 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DIGBIBDE_01708 5.4e-44 spiA K sequence-specific DNA binding
DIGBIBDE_01710 1.3e-134 agrA KT LytTr DNA-binding domain
DIGBIBDE_01711 2.7e-228 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
DIGBIBDE_01717 1.5e-25 S Bacteriocin class II with double-glycine leader peptide
DIGBIBDE_01718 0.0 mdlB V abc transporter atp-binding protein
DIGBIBDE_01719 0.0 mdlA V abc transporter atp-binding protein
DIGBIBDE_01722 2.1e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
DIGBIBDE_01723 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DIGBIBDE_01724 1.8e-61 yutD J protein conserved in bacteria
DIGBIBDE_01725 1.1e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DIGBIBDE_01728 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DIGBIBDE_01729 2e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIGBIBDE_01730 0.0 ftsI 3.4.16.4 M penicillin-binding protein
DIGBIBDE_01731 4e-45 ftsL D cell division protein FtsL
DIGBIBDE_01732 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DIGBIBDE_01734 3.7e-25
DIGBIBDE_01737 5e-69 yhaI J Protein of unknown function (DUF805)
DIGBIBDE_01738 4.3e-65 yhaI S Protein of unknown function (DUF805)
DIGBIBDE_01739 2.9e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DIGBIBDE_01740 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DIGBIBDE_01741 6.8e-279 XK27_00765
DIGBIBDE_01742 1.7e-131 ecsA_2 V abc transporter atp-binding protein
DIGBIBDE_01743 3.1e-125 S Protein of unknown function (DUF554)
DIGBIBDE_01744 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DIGBIBDE_01745 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DIGBIBDE_01746 2.1e-244 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_01747 3.1e-237 dcuS 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_01748 8.9e-14
DIGBIBDE_01751 1.1e-144 V Psort location CytoplasmicMembrane, score
DIGBIBDE_01753 1.2e-296 O MreB/Mbl protein
DIGBIBDE_01754 1.3e-190 mccF V LD-carboxypeptidase
DIGBIBDE_01755 2.4e-119 liaI S membrane
DIGBIBDE_01756 2.2e-73 XK27_02470 K LytTr DNA-binding domain
DIGBIBDE_01757 1.2e-292 KT response to antibiotic
DIGBIBDE_01758 1.5e-110 yebC M Membrane
DIGBIBDE_01759 1.8e-259 XK27_03190 S hydrolases of the HAD superfamily
DIGBIBDE_01760 1.6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DIGBIBDE_01762 2.9e-31 yozG K Transcriptional regulator
DIGBIBDE_01766 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIGBIBDE_01767 3.1e-206 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIGBIBDE_01768 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DIGBIBDE_01769 6.2e-207 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DIGBIBDE_01770 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DIGBIBDE_01771 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DIGBIBDE_01773 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
DIGBIBDE_01774 5.3e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
DIGBIBDE_01775 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
DIGBIBDE_01776 5.1e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
DIGBIBDE_01777 4.4e-180 scrR K Transcriptional regulator
DIGBIBDE_01778 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIGBIBDE_01779 1.7e-61 yqhY S protein conserved in bacteria
DIGBIBDE_01780 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIGBIBDE_01781 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
DIGBIBDE_01782 1.8e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
DIGBIBDE_01784 6.1e-146 V 'abc transporter, ATP-binding protein
DIGBIBDE_01785 7.2e-33 blpT
DIGBIBDE_01789 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIGBIBDE_01790 1e-168 corA P COG0598 Mg2 and Co2 transporters
DIGBIBDE_01791 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
DIGBIBDE_01793 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DIGBIBDE_01794 4.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DIGBIBDE_01795 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
DIGBIBDE_01796 1.1e-42 XK27_05745
DIGBIBDE_01797 6.1e-229 mutY L A G-specific adenine glycosylase
DIGBIBDE_01798 4.8e-07
DIGBIBDE_01799 1.3e-37
DIGBIBDE_01801 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIGBIBDE_01802 1.9e-93 salR K helix_turn_helix, Lux Regulon
DIGBIBDE_01803 3.8e-274 2.7.13.3 T Histidine kinase
DIGBIBDE_01804 0.0 V ABC transporter (Permease
DIGBIBDE_01806 2.5e-225 V ABC transporter (Permease
DIGBIBDE_01807 6e-129 V ABC transporter, ATP-binding protein
DIGBIBDE_01808 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DIGBIBDE_01809 4.1e-90 cvpA S toxin biosynthetic process
DIGBIBDE_01810 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DIGBIBDE_01811 1.3e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIGBIBDE_01812 3.7e-114 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DIGBIBDE_01813 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DIGBIBDE_01814 3.7e-46 azlD S branched-chain amino acid
DIGBIBDE_01815 3e-114 azlC E AzlC protein
DIGBIBDE_01816 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIGBIBDE_01817 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DIGBIBDE_01818 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
DIGBIBDE_01819 1.5e-33 ykzG S Belongs to the UPF0356 family
DIGBIBDE_01820 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIGBIBDE_01821 6.6e-116 pscB M CHAP domain protein
DIGBIBDE_01822 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
DIGBIBDE_01823 2.5e-62 glnR K Transcriptional regulator
DIGBIBDE_01824 3e-87 S Fusaric acid resistance protein-like
DIGBIBDE_01825 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DIGBIBDE_01826 7.1e-14
DIGBIBDE_01827 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DIGBIBDE_01828 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DIGBIBDE_01829 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DIGBIBDE_01830 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DIGBIBDE_01831 4e-142 purR 2.4.2.7 F operon repressor
DIGBIBDE_01832 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
DIGBIBDE_01833 1.6e-169 rmuC S RmuC domain protein
DIGBIBDE_01834 1.6e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
DIGBIBDE_01835 2.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DIGBIBDE_01836 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DIGBIBDE_01838 2.2e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DIGBIBDE_01839 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DIGBIBDE_01840 6.6e-145 tatD L Hydrolase, tatd
DIGBIBDE_01841 7.2e-74 yccU S CoA-binding protein
DIGBIBDE_01842 6.3e-51 trxA O Belongs to the thioredoxin family
DIGBIBDE_01843 6e-143 S Macro domain protein
DIGBIBDE_01844 6.7e-61 L thioesterase
DIGBIBDE_01845 1e-51 bta 1.8.1.8 CO cell redox homeostasis
DIGBIBDE_01848 2.2e-223 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DIGBIBDE_01849 3.4e-14 rpmH J Ribosomal protein L34
DIGBIBDE_01850 2.4e-101 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
DIGBIBDE_01851 1.1e-104 K Transcriptional regulator
DIGBIBDE_01852 5.1e-174 jag S RNA-binding protein
DIGBIBDE_01853 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DIGBIBDE_01854 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DIGBIBDE_01855 6.3e-268 argH 4.3.2.1 E Argininosuccinate lyase
DIGBIBDE_01856 2.2e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DIGBIBDE_01857 2.8e-134 fasA KT Response regulator of the LytR AlgR family
DIGBIBDE_01858 1.7e-243 fasC 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_01859 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_01860 1e-154 hpk9 2.7.13.3 T protein histidine kinase activity
DIGBIBDE_01861 4.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
DIGBIBDE_01862 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIGBIBDE_01863 0.0 amiA E ABC transporter, substrate-binding protein, family 5
DIGBIBDE_01864 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DIGBIBDE_01865 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DIGBIBDE_01866 1.2e-50 S Protein of unknown function (DUF3397)
DIGBIBDE_01867 3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DIGBIBDE_01868 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
DIGBIBDE_01869 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DIGBIBDE_01870 3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
DIGBIBDE_01871 1.2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DIGBIBDE_01872 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
DIGBIBDE_01873 7.9e-230 XK27_09615 C reductase
DIGBIBDE_01874 1.2e-138 fnt P Formate nitrite transporter
DIGBIBDE_01875 1.1e-98 XK27_08585 S Psort location CytoplasmicMembrane, score
DIGBIBDE_01876 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DIGBIBDE_01877 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DIGBIBDE_01878 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
DIGBIBDE_01879 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DIGBIBDE_01880 2.1e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DIGBIBDE_01881 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DIGBIBDE_01882 1.8e-141 S HAD hydrolase, family IA, variant
DIGBIBDE_01883 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
DIGBIBDE_01887 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DIGBIBDE_01888 2.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DIGBIBDE_01889 8.3e-37 yeeD O sulfur carrier activity
DIGBIBDE_01890 5.8e-186 yeeE S Sulphur transport
DIGBIBDE_01891 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DIGBIBDE_01892 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DIGBIBDE_01893 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
DIGBIBDE_01894 2e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
DIGBIBDE_01895 3.7e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIGBIBDE_01896 3e-103 S CAAX amino terminal protease family protein
DIGBIBDE_01898 2.1e-109 V CAAX protease self-immunity
DIGBIBDE_01899 8.8e-27 lanR K sequence-specific DNA binding
DIGBIBDE_01900 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIGBIBDE_01901 2.5e-175 ytxK 2.1.1.72 L DNA methylase
DIGBIBDE_01902 2e-12 comGF U Putative Competence protein ComGF
DIGBIBDE_01903 2e-71 comGF U Competence protein ComGF
DIGBIBDE_01904 3.1e-15 NU Type II secretory pathway pseudopilin
DIGBIBDE_01905 8.4e-70 cglD NU Competence protein
DIGBIBDE_01906 2.2e-43 comGC U Required for transformation and DNA binding
DIGBIBDE_01907 2.4e-159 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DIGBIBDE_01908 9.3e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DIGBIBDE_01909 1e-68 S cog cog4699
DIGBIBDE_01910 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIGBIBDE_01911 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIGBIBDE_01912 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DIGBIBDE_01913 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIGBIBDE_01914 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DIGBIBDE_01915 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
DIGBIBDE_01916 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
DIGBIBDE_01917 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DIGBIBDE_01918 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
DIGBIBDE_01919 1.4e-57 asp S cog cog1302
DIGBIBDE_01920 7.1e-226 norN V Mate efflux family protein
DIGBIBDE_01921 1.3e-276 thrC 4.2.3.1 E Threonine synthase
DIGBIBDE_01924 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DIGBIBDE_01925 0.0 pepO 3.4.24.71 O Peptidase family M13
DIGBIBDE_01926 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DIGBIBDE_01927 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
DIGBIBDE_01928 2.3e-125 treR K trehalose operon
DIGBIBDE_01929 4.3e-95 ywlG S Belongs to the UPF0340 family
DIGBIBDE_01932 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
DIGBIBDE_01934 8.1e-238 6.3.2.2 H gamma-glutamylcysteine synthetase
DIGBIBDE_01935 1.3e-85 L Transposase
DIGBIBDE_01936 4.8e-52 L Transposase
DIGBIBDE_01937 4.4e-62 rplQ J ribosomal protein l17
DIGBIBDE_01938 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIGBIBDE_01939 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DIGBIBDE_01940 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DIGBIBDE_01941 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DIGBIBDE_01942 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DIGBIBDE_01943 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DIGBIBDE_01944 4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DIGBIBDE_01945 5.7e-58 rplO J binds to the 23S rRNA
DIGBIBDE_01946 1.9e-23 rpmD J ribosomal protein l30
DIGBIBDE_01947 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DIGBIBDE_01948 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DIGBIBDE_01949 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DIGBIBDE_01950 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DIGBIBDE_01951 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIGBIBDE_01952 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DIGBIBDE_01953 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DIGBIBDE_01954 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DIGBIBDE_01955 1.7e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DIGBIBDE_01956 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
DIGBIBDE_01957 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DIGBIBDE_01958 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DIGBIBDE_01959 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DIGBIBDE_01960 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DIGBIBDE_01961 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DIGBIBDE_01962 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DIGBIBDE_01963 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
DIGBIBDE_01964 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIGBIBDE_01965 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
DIGBIBDE_01966 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DIGBIBDE_01967 0.0 XK27_09800 I Acyltransferase
DIGBIBDE_01968 9.7e-36 XK27_09805 S MORN repeat protein
DIGBIBDE_01969 1.7e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIGBIBDE_01970 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIGBIBDE_01971 5.7e-94 adk 2.7.4.3 F topology modulation protein
DIGBIBDE_01973 4.9e-174 yeiH S membrane
DIGBIBDE_01974 5.5e-89 K sequence-specific DNA binding
DIGBIBDE_01975 1.2e-156 L Replication initiation factor
DIGBIBDE_01976 1.9e-18 S Domain of unknown function (DUF3173)
DIGBIBDE_01977 1.5e-214 int L Belongs to the 'phage' integrase family
DIGBIBDE_01979 1.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
DIGBIBDE_01980 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DIGBIBDE_01981 6.3e-44 yrzL S Belongs to the UPF0297 family
DIGBIBDE_01982 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIGBIBDE_01983 3.2e-44 yrzB S Belongs to the UPF0473 family
DIGBIBDE_01984 8.1e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
DIGBIBDE_01985 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DIGBIBDE_01986 7.5e-14
DIGBIBDE_01987 5.4e-89 XK27_10930 K acetyltransferase
DIGBIBDE_01988 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DIGBIBDE_01989 6.1e-85 yaaA S Belongs to the UPF0246 family
DIGBIBDE_01990 1.5e-23 yaaA S Belongs to the UPF0246 family
DIGBIBDE_01991 2.7e-166 XK27_01785 S cog cog1284
DIGBIBDE_01992 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DIGBIBDE_01994 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
DIGBIBDE_01995 1.8e-240 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
DIGBIBDE_01996 3.3e-219 metE 2.1.1.14 E Methionine synthase
DIGBIBDE_01997 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DIGBIBDE_01998 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DIGBIBDE_02000 3.3e-117 nudL L hydrolase
DIGBIBDE_02001 9.1e-53 K transcriptional regulator, PadR family
DIGBIBDE_02002 1.9e-61 XK27_06920 S Protein of unknown function (DUF1700)
DIGBIBDE_02003 3.7e-106 S Putative adhesin
DIGBIBDE_02004 1.2e-157 XK27_06930 V domain protein
DIGBIBDE_02005 4.6e-94 XK27_06935 K transcriptional regulator
DIGBIBDE_02006 3.8e-52 ypaA M Membrane
DIGBIBDE_02007 1.9e-10
DIGBIBDE_02008 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DIGBIBDE_02009 1.8e-47 veg S Biofilm formation stimulator VEG
DIGBIBDE_02010 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DIGBIBDE_02011 2.2e-73 rplI J binds to the 23S rRNA
DIGBIBDE_02012 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DIGBIBDE_02013 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DIGBIBDE_02014 4.2e-99 yvbG U UPF0056 membrane protein
DIGBIBDE_02015 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DIGBIBDE_02016 2.4e-311 S Bacterial membrane protein, YfhO
DIGBIBDE_02017 3.2e-63 isaA GH23 M Immunodominant staphylococcal antigen A
DIGBIBDE_02018 3.3e-58 lytE M LysM domain protein
DIGBIBDE_02019 1.7e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIGBIBDE_02020 3.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIGBIBDE_02021 3.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIGBIBDE_02022 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIGBIBDE_02023 8.3e-130 S sequence-specific DNA binding
DIGBIBDE_02024 4.3e-239 ymfH S Peptidase M16
DIGBIBDE_02025 1e-229 ymfF S Peptidase M16
DIGBIBDE_02026 3.7e-58 yaaA S S4 domain protein YaaA
DIGBIBDE_02027 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIGBIBDE_02028 8.1e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DIGBIBDE_02029 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
DIGBIBDE_02030 7.1e-153 yvjA S membrane
DIGBIBDE_02031 1.1e-305 ybiT S abc transporter atp-binding protein
DIGBIBDE_02032 0.0 XK27_10405 S Bacterial membrane protein YfhO
DIGBIBDE_02036 6.2e-120 yoaK S Protein of unknown function (DUF1275)
DIGBIBDE_02037 4.8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DIGBIBDE_02038 2.4e-202 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
DIGBIBDE_02039 1.1e-133 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)