ORF_ID e_value Gene_name EC_number CAZy COGs Description
GHHKAJPP_00001 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GHHKAJPP_00002 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GHHKAJPP_00003 3.2e-29 yyzM S Protein conserved in bacteria
GHHKAJPP_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GHHKAJPP_00005 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GHHKAJPP_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHHKAJPP_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GHHKAJPP_00008 3e-60 divIC D Septum formation initiator
GHHKAJPP_00010 3.2e-234 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
GHHKAJPP_00011 7.7e-233 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GHHKAJPP_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHHKAJPP_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHHKAJPP_00026 2.6e-10
GHHKAJPP_00032 2.4e-110 mreC M Involved in formation and maintenance of cell shape
GHHKAJPP_00033 7.4e-81 mreD M rod shape-determining protein MreD
GHHKAJPP_00034 1.9e-84 usp 3.5.1.28 CBM50 S CHAP domain
GHHKAJPP_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHHKAJPP_00036 1.9e-223 L Transposase
GHHKAJPP_00037 4.7e-216 araT 2.6.1.1 E Aminotransferase
GHHKAJPP_00038 8e-140 recO L Involved in DNA repair and RecF pathway recombination
GHHKAJPP_00039 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GHHKAJPP_00040 1.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHHKAJPP_00041 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GHHKAJPP_00042 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHHKAJPP_00043 3e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GHHKAJPP_00044 3.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GHHKAJPP_00045 5.4e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GHHKAJPP_00046 8.9e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GHHKAJPP_00047 6.1e-219 L Transposase
GHHKAJPP_00048 1.2e-12 L Transposase
GHHKAJPP_00049 5e-232 S AAA ATPase domain
GHHKAJPP_00050 8.9e-124 dam2 2.1.1.72 L DNA methyltransferase
GHHKAJPP_00051 1.7e-156 S CHAP domain
GHHKAJPP_00052 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
GHHKAJPP_00053 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GHHKAJPP_00054 2.3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GHHKAJPP_00055 1.3e-173 1.1.1.169 H Ketopantoate reductase
GHHKAJPP_00056 4.2e-33
GHHKAJPP_00057 1.8e-84
GHHKAJPP_00058 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GHHKAJPP_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GHHKAJPP_00061 3.4e-68 argR K Regulates arginine biosynthesis genes
GHHKAJPP_00062 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GHHKAJPP_00063 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GHHKAJPP_00064 1.5e-77 S Protein of unknown function (DUF3021)
GHHKAJPP_00065 1.1e-69 K LytTr DNA-binding domain
GHHKAJPP_00067 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GHHKAJPP_00069 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GHHKAJPP_00070 7.3e-103 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
GHHKAJPP_00071 1.2e-225 cinA 3.5.1.42 S Belongs to the CinA family
GHHKAJPP_00072 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GHHKAJPP_00073 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
GHHKAJPP_00079 2.6e-10
GHHKAJPP_00081 1.9e-07
GHHKAJPP_00086 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHHKAJPP_00087 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GHHKAJPP_00088 1.2e-35 XK27_02060 S Transglycosylase associated protein
GHHKAJPP_00089 1.5e-71 badR K Transcriptional regulator, marr family
GHHKAJPP_00090 3.2e-95 S reductase
GHHKAJPP_00092 1.4e-284 ahpF O alkyl hydroperoxide reductase
GHHKAJPP_00093 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
GHHKAJPP_00094 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GHHKAJPP_00095 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GHHKAJPP_00096 1.6e-82 S Putative small multi-drug export protein
GHHKAJPP_00097 3.1e-75 ctsR K Belongs to the CtsR family
GHHKAJPP_00098 0.0 clpC O Belongs to the ClpA ClpB family
GHHKAJPP_00099 2.2e-232 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GHHKAJPP_00100 1.6e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GHHKAJPP_00101 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GHHKAJPP_00102 4.7e-140 S SseB protein N-terminal domain
GHHKAJPP_00103 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
GHHKAJPP_00105 3.1e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHHKAJPP_00106 3.6e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GHHKAJPP_00108 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHHKAJPP_00109 6e-91 yacP S RNA-binding protein containing a PIN domain
GHHKAJPP_00110 5.4e-153 degV S DegV family
GHHKAJPP_00112 5.1e-22 K Transcriptional
GHHKAJPP_00113 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GHHKAJPP_00114 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GHHKAJPP_00115 6e-191 L Phage integrase family
GHHKAJPP_00116 2.5e-23
GHHKAJPP_00119 3.3e-148 repB EP Plasmid replication protein
GHHKAJPP_00120 8.1e-09
GHHKAJPP_00121 8.7e-180 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GHHKAJPP_00122 2.5e-10
GHHKAJPP_00123 4.5e-171 D nuclear chromosome segregation
GHHKAJPP_00126 1.3e-17
GHHKAJPP_00127 1.5e-29 K Helix-turn-helix domain
GHHKAJPP_00129 8.6e-148 srtB 3.4.22.70 S Sortase family
GHHKAJPP_00130 9.7e-233 capA M Bacterial capsule synthesis protein
GHHKAJPP_00131 2.3e-38 gcvR T UPF0237 protein
GHHKAJPP_00132 2.1e-241 XK27_08635 S UPF0210 protein
GHHKAJPP_00133 4.3e-132 ais G Phosphoglycerate mutase
GHHKAJPP_00134 7e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GHHKAJPP_00135 3.6e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
GHHKAJPP_00136 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GHHKAJPP_00137 9.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GHHKAJPP_00138 1.4e-304 dnaK O Heat shock 70 kDa protein
GHHKAJPP_00139 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GHHKAJPP_00140 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GHHKAJPP_00141 3.8e-134 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
GHHKAJPP_00142 1.1e-78 hmpT S cog cog4720
GHHKAJPP_00155 3.9e-87 sigH K DNA-templated transcription, initiation
GHHKAJPP_00156 2.3e-134 ykuT M mechanosensitive ion channel
GHHKAJPP_00157 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHHKAJPP_00158 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GHHKAJPP_00159 2.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GHHKAJPP_00160 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
GHHKAJPP_00161 7.8e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
GHHKAJPP_00162 1.3e-57 XK27_02675 K Acetyltransferase GNAT Family
GHHKAJPP_00163 8.9e-14 XK27_02675 K Acetyltransferase GNAT Family
GHHKAJPP_00164 3.5e-177 prmA J Ribosomal protein L11 methyltransferase
GHHKAJPP_00165 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GHHKAJPP_00166 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GHHKAJPP_00167 9.1e-83 nrdI F Belongs to the NrdI family
GHHKAJPP_00168 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHHKAJPP_00169 2.4e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GHHKAJPP_00170 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
GHHKAJPP_00171 7.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GHHKAJPP_00172 1.9e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHHKAJPP_00173 1.1e-102 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GHHKAJPP_00174 7.4e-182 yhjX P Major Facilitator
GHHKAJPP_00175 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GHHKAJPP_00176 4.4e-82 V VanZ like family
GHHKAJPP_00177 1.8e-180 D nuclear chromosome segregation
GHHKAJPP_00178 2.2e-123 glnQ E abc transporter atp-binding protein
GHHKAJPP_00179 4.3e-270 glnP P ABC transporter
GHHKAJPP_00180 4.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GHHKAJPP_00181 4.1e-17 S Protein of unknown function (DUF3021)
GHHKAJPP_00182 1e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GHHKAJPP_00183 7.4e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
GHHKAJPP_00184 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GHHKAJPP_00185 6.9e-234 sufD O assembly protein SufD
GHHKAJPP_00186 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHHKAJPP_00187 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
GHHKAJPP_00188 2.9e-273 sufB O assembly protein SufB
GHHKAJPP_00189 4.7e-26
GHHKAJPP_00190 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GHHKAJPP_00191 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHHKAJPP_00192 1e-70 adcR K transcriptional
GHHKAJPP_00193 7.1e-135 adcC P ABC transporter, ATP-binding protein
GHHKAJPP_00194 1.9e-128 adcB P ABC transporter (Permease
GHHKAJPP_00195 2.9e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
GHHKAJPP_00196 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_00197 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
GHHKAJPP_00198 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
GHHKAJPP_00199 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GHHKAJPP_00200 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
GHHKAJPP_00201 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
GHHKAJPP_00202 1.1e-95 srlA G PTS system glucitol sorbitol-specific
GHHKAJPP_00203 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
GHHKAJPP_00204 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
GHHKAJPP_00205 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
GHHKAJPP_00206 9.2e-59 L MULE transposase domain
GHHKAJPP_00207 1.1e-108 L Transposase IS116 IS110 IS902
GHHKAJPP_00208 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHHKAJPP_00209 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
GHHKAJPP_00210 1.4e-153 Z012_04635 K sequence-specific DNA binding
GHHKAJPP_00211 1.1e-276 V ABC transporter
GHHKAJPP_00212 6.1e-126 yeeN K transcriptional regulatory protein
GHHKAJPP_00213 2.9e-46 yajC U protein transport
GHHKAJPP_00214 2.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHHKAJPP_00215 6.7e-142 cdsA 2.7.7.41 S Belongs to the CDS family
GHHKAJPP_00216 3.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GHHKAJPP_00217 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GHHKAJPP_00218 0.0 WQ51_06230 S ABC transporter
GHHKAJPP_00219 5.2e-142 cmpC S abc transporter atp-binding protein
GHHKAJPP_00220 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GHHKAJPP_00221 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GHHKAJPP_00223 1.5e-44
GHHKAJPP_00224 7.6e-55 S TM2 domain
GHHKAJPP_00225 3.5e-160 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHHKAJPP_00226 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GHHKAJPP_00227 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GHHKAJPP_00228 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
GHHKAJPP_00229 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
GHHKAJPP_00230 4.3e-69 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
GHHKAJPP_00231 2.5e-144 cof S Sucrose-6F-phosphate phosphohydrolase
GHHKAJPP_00232 6.5e-134 glcR K transcriptional regulator (DeoR family)
GHHKAJPP_00233 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHHKAJPP_00234 6.5e-73 K transcriptional
GHHKAJPP_00235 1.8e-223 S COG1073 Hydrolases of the alpha beta superfamily
GHHKAJPP_00236 4.7e-38 yjdF S Protein of unknown function (DUF2992)
GHHKAJPP_00237 2.2e-45 3.2.2.21 S YCII-related domain
GHHKAJPP_00238 1.5e-52 K regulation of RNA biosynthetic process
GHHKAJPP_00239 1.3e-154 cylA V abc transporter atp-binding protein
GHHKAJPP_00240 9.3e-134 cylB V ABC-2 type transporter
GHHKAJPP_00241 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
GHHKAJPP_00242 4.8e-30 S Protein of unknown function (DUF3021)
GHHKAJPP_00243 5.8e-121 mta K Transcriptional
GHHKAJPP_00244 2.4e-119 yhcA V abc transporter atp-binding protein
GHHKAJPP_00245 3e-216 macB_2 V FtsX-like permease family
GHHKAJPP_00246 1.1e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHHKAJPP_00247 2e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GHHKAJPP_00248 2.9e-70 yhaI S Protein of unknown function (DUF805)
GHHKAJPP_00249 8.4e-254 pepC 3.4.22.40 E aminopeptidase
GHHKAJPP_00250 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GHHKAJPP_00251 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GHHKAJPP_00252 9.8e-94 ypsA S Belongs to the UPF0398 family
GHHKAJPP_00253 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GHHKAJPP_00254 3.7e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GHHKAJPP_00255 1.2e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GHHKAJPP_00256 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
GHHKAJPP_00257 4.8e-22
GHHKAJPP_00258 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GHHKAJPP_00259 1e-84 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
GHHKAJPP_00260 3.1e-289 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GHHKAJPP_00261 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHHKAJPP_00262 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHHKAJPP_00263 1.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GHHKAJPP_00264 2.3e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHHKAJPP_00265 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
GHHKAJPP_00266 2.1e-99 ybhL S Belongs to the BI1 family
GHHKAJPP_00267 3.2e-12 ycdA S Domain of unknown function (DUF4352)
GHHKAJPP_00268 6.9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GHHKAJPP_00269 4.1e-90 K transcriptional regulator
GHHKAJPP_00270 1.6e-36 yneF S UPF0154 protein
GHHKAJPP_00271 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GHHKAJPP_00272 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GHHKAJPP_00273 1.6e-96 XK27_09740 S Phosphoesterase
GHHKAJPP_00274 2.7e-85 ykuL S CBS domain
GHHKAJPP_00275 1e-126 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GHHKAJPP_00276 5.3e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GHHKAJPP_00277 2.6e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GHHKAJPP_00278 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHHKAJPP_00279 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GHHKAJPP_00280 1e-257 trkH P Cation transport protein
GHHKAJPP_00281 1e-246 trkA P Potassium transporter peripheral membrane component
GHHKAJPP_00282 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GHHKAJPP_00283 2.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GHHKAJPP_00284 5.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
GHHKAJPP_00285 7.1e-156 K sequence-specific DNA binding
GHHKAJPP_00286 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GHHKAJPP_00287 2.4e-53 yhaI L Membrane
GHHKAJPP_00288 2.1e-244 S Domain of unknown function (DUF4173)
GHHKAJPP_00289 6.8e-95 ureI S AmiS/UreI family transporter
GHHKAJPP_00290 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GHHKAJPP_00291 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GHHKAJPP_00292 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GHHKAJPP_00293 5.6e-77 ureE O enzyme active site formation
GHHKAJPP_00294 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GHHKAJPP_00295 4.7e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GHHKAJPP_00296 1.5e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GHHKAJPP_00297 3.3e-175 cbiM P biosynthesis protein CbiM
GHHKAJPP_00298 5.4e-136 P cobalt transport protein
GHHKAJPP_00299 7.7e-129 cbiO P ABC transporter
GHHKAJPP_00300 6.3e-138 ET ABC transporter substrate-binding protein
GHHKAJPP_00301 1.6e-163 metQ M Belongs to the NlpA lipoprotein family
GHHKAJPP_00302 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GHHKAJPP_00303 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHHKAJPP_00304 1.2e-99 metI P ABC transporter (Permease
GHHKAJPP_00305 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GHHKAJPP_00306 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
GHHKAJPP_00307 8e-94 S UPF0397 protein
GHHKAJPP_00308 9.6e-308 ykoD P abc transporter atp-binding protein
GHHKAJPP_00309 1.9e-147 cbiQ P cobalt transport
GHHKAJPP_00310 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
GHHKAJPP_00311 1.1e-232 P COG0168 Trk-type K transport systems, membrane components
GHHKAJPP_00312 3.2e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
GHHKAJPP_00313 1.5e-89 yceD K metal-binding, possibly nucleic acid-binding protein
GHHKAJPP_00314 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GHHKAJPP_00315 2.5e-278 T PhoQ Sensor
GHHKAJPP_00316 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GHHKAJPP_00317 2e-211 dnaB L Replication initiation and membrane attachment
GHHKAJPP_00318 2.4e-164 dnaI L Primosomal protein DnaI
GHHKAJPP_00319 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GHHKAJPP_00320 1.2e-104
GHHKAJPP_00321 1.8e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GHHKAJPP_00322 2.5e-62 manO S protein conserved in bacteria
GHHKAJPP_00323 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
GHHKAJPP_00324 4.5e-117 manM G pts system
GHHKAJPP_00325 4.9e-174 manL 2.7.1.191 G pts system
GHHKAJPP_00326 7.7e-67 manO S Protein conserved in bacteria
GHHKAJPP_00327 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
GHHKAJPP_00328 4.7e-135 manY G pts system
GHHKAJPP_00329 6.2e-169 manL 2.7.1.191 G pts system
GHHKAJPP_00330 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
GHHKAJPP_00331 1.3e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GHHKAJPP_00332 6.2e-247 pbuO S permease
GHHKAJPP_00333 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
GHHKAJPP_00334 1.1e-87 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
GHHKAJPP_00335 9.8e-188 brpA K Transcriptional
GHHKAJPP_00336 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
GHHKAJPP_00337 2.4e-196 nusA K Participates in both transcription termination and antitermination
GHHKAJPP_00338 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
GHHKAJPP_00339 8e-42 ylxQ J ribosomal protein
GHHKAJPP_00340 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHHKAJPP_00341 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GHHKAJPP_00342 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
GHHKAJPP_00343 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
GHHKAJPP_00344 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHHKAJPP_00345 1.3e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
GHHKAJPP_00346 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
GHHKAJPP_00347 7.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
GHHKAJPP_00348 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GHHKAJPP_00349 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GHHKAJPP_00350 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
GHHKAJPP_00351 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GHHKAJPP_00352 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHHKAJPP_00353 3.2e-72 ylbF S Belongs to the UPF0342 family
GHHKAJPP_00354 7.1e-46 ylbG S UPF0298 protein
GHHKAJPP_00355 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GHHKAJPP_00356 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
GHHKAJPP_00357 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
GHHKAJPP_00358 2.4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GHHKAJPP_00359 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GHHKAJPP_00360 9.6e-110 acuB S CBS domain
GHHKAJPP_00361 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GHHKAJPP_00362 2.9e-108 yvyE 3.4.13.9 S YigZ family
GHHKAJPP_00363 5.7e-239 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GHHKAJPP_00364 6.5e-98 comFC K competence protein
GHHKAJPP_00365 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHHKAJPP_00373 1.1e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
GHHKAJPP_00374 2.8e-103 S Domain of unknown function (DUF1803)
GHHKAJPP_00375 7.8e-102 ygaC J Belongs to the UPF0374 family
GHHKAJPP_00376 4.1e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
GHHKAJPP_00377 2.6e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHHKAJPP_00378 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
GHHKAJPP_00379 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
GHHKAJPP_00380 2.8e-114 S HAD hydrolase, family IA, variant 3
GHHKAJPP_00381 4.8e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
GHHKAJPP_00382 5.2e-72 marR K Transcriptional regulator, MarR family
GHHKAJPP_00383 3.2e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GHHKAJPP_00384 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHHKAJPP_00385 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
GHHKAJPP_00386 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GHHKAJPP_00387 6.2e-126 IQ reductase
GHHKAJPP_00388 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GHHKAJPP_00389 9.4e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GHHKAJPP_00390 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GHHKAJPP_00391 3.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GHHKAJPP_00392 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GHHKAJPP_00393 1.8e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GHHKAJPP_00394 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GHHKAJPP_00395 1.2e-206 rny D Endoribonuclease that initiates mRNA decay
GHHKAJPP_00396 3.1e-125 fruR K transcriptional
GHHKAJPP_00397 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GHHKAJPP_00398 0.0 fruA 2.7.1.202 G phosphotransferase system
GHHKAJPP_00399 5.9e-255 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHHKAJPP_00400 1.2e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHHKAJPP_00402 1.7e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GHHKAJPP_00403 9.7e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHHKAJPP_00404 3.1e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GHHKAJPP_00405 7.7e-252 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GHHKAJPP_00406 6.2e-83 2.3.1.128 K acetyltransferase
GHHKAJPP_00407 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GHHKAJPP_00408 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GHHKAJPP_00409 2.7e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHHKAJPP_00410 5e-63 WQ51_03320 S cog cog4835
GHHKAJPP_00411 2.8e-146 XK27_08360 S EDD domain protein, DegV family
GHHKAJPP_00412 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHHKAJPP_00413 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GHHKAJPP_00414 0.0 yfmR S abc transporter atp-binding protein
GHHKAJPP_00415 5e-26 U response to pH
GHHKAJPP_00416 2.4e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
GHHKAJPP_00417 1.8e-43 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
GHHKAJPP_00418 1e-153 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
GHHKAJPP_00419 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GHHKAJPP_00420 1.4e-266 S Psort location CytoplasmicMembrane, score
GHHKAJPP_00421 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GHHKAJPP_00422 1.4e-72 K DNA-binding transcription factor activity
GHHKAJPP_00423 5e-310 lmrA1 V abc transporter atp-binding protein
GHHKAJPP_00424 0.0 lmrA2 V abc transporter atp-binding protein
GHHKAJPP_00425 1.3e-111 K Acetyltransferase (GNAT) family
GHHKAJPP_00426 1.3e-111 2.7.6.5 S Region found in RelA / SpoT proteins
GHHKAJPP_00427 9.2e-116 T response regulator
GHHKAJPP_00428 1.5e-209 sptS 2.7.13.3 T Histidine kinase
GHHKAJPP_00429 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GHHKAJPP_00430 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GHHKAJPP_00431 8.5e-159 cvfB S Protein conserved in bacteria
GHHKAJPP_00432 3.7e-34 yozE S Belongs to the UPF0346 family
GHHKAJPP_00433 3.9e-128 sip M LysM domain protein
GHHKAJPP_00434 3.7e-188 phoH T phosphate starvation-inducible protein PhoH
GHHKAJPP_00440 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHHKAJPP_00441 2.9e-159 S reductase
GHHKAJPP_00442 5.2e-167 K transcriptional regulator (lysR family)
GHHKAJPP_00443 1e-104 S CAAX amino terminal protease family protein
GHHKAJPP_00444 6.4e-279 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHHKAJPP_00445 5.2e-165 coiA 3.6.4.12 S Competence protein
GHHKAJPP_00446 0.0 pepF E oligoendopeptidase F
GHHKAJPP_00447 5.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
GHHKAJPP_00448 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
GHHKAJPP_00449 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
GHHKAJPP_00450 3e-84 yxjI S LURP-one-related
GHHKAJPP_00451 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GHHKAJPP_00454 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
GHHKAJPP_00455 1.8e-133 agrA KT phosphorelay signal transduction system
GHHKAJPP_00456 1.5e-142 2.7.13.3 T GHKL domain
GHHKAJPP_00457 3.6e-68 2.7.13.3 T GHKL domain
GHHKAJPP_00459 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
GHHKAJPP_00460 2.2e-137 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GHHKAJPP_00461 3.3e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
GHHKAJPP_00462 8e-180 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GHHKAJPP_00463 9.5e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GHHKAJPP_00464 3.8e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GHHKAJPP_00465 2e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GHHKAJPP_00466 7.2e-129 yxkH G deacetylase
GHHKAJPP_00467 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GHHKAJPP_00468 5.9e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHHKAJPP_00469 5.3e-148 rarD S Transporter
GHHKAJPP_00470 4e-17 T peptidase
GHHKAJPP_00471 1.4e-14 coiA 3.6.4.12 S Competence protein
GHHKAJPP_00474 4e-104 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GHHKAJPP_00475 3e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
GHHKAJPP_00476 1.5e-95 F AAA domain
GHHKAJPP_00477 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GHHKAJPP_00478 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHHKAJPP_00479 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
GHHKAJPP_00480 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GHHKAJPP_00481 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHHKAJPP_00482 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GHHKAJPP_00483 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHHKAJPP_00484 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GHHKAJPP_00485 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GHHKAJPP_00486 3.5e-217 ftsW D Belongs to the SEDS family
GHHKAJPP_00487 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GHHKAJPP_00488 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHHKAJPP_00489 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GHHKAJPP_00491 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHHKAJPP_00492 2.7e-160 holB 2.7.7.7 L dna polymerase iii
GHHKAJPP_00493 4.4e-133 yaaT S stage 0 sporulation protein
GHHKAJPP_00494 1.2e-54 yabA L Involved in initiation control of chromosome replication
GHHKAJPP_00495 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHHKAJPP_00496 1.8e-148 amt P Ammonium Transporter
GHHKAJPP_00497 2.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
GHHKAJPP_00498 1.2e-141 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
GHHKAJPP_00499 2e-75 S Bacterial inner membrane protein
GHHKAJPP_00500 5.2e-113 3.4.17.14, 3.5.1.28 NU amidase activity
GHHKAJPP_00501 3.5e-294 nptA P COG1283 Na phosphate symporter
GHHKAJPP_00502 5.7e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHHKAJPP_00503 9.6e-220 S membrane
GHHKAJPP_00504 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GHHKAJPP_00505 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GHHKAJPP_00506 1.7e-38 ynzC S UPF0291 protein
GHHKAJPP_00507 4.8e-252 cycA E permease
GHHKAJPP_00508 6.4e-10 uvrX 2.7.7.7 L impB/mucB/samB family
GHHKAJPP_00509 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_00510 1.5e-138 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHHKAJPP_00514 5.8e-69 K Helix-turn-helix
GHHKAJPP_00515 1.6e-41
GHHKAJPP_00517 4.7e-168 fhuR K transcriptional regulator (lysR family)
GHHKAJPP_00518 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GHHKAJPP_00519 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHHKAJPP_00520 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHHKAJPP_00521 4e-221 pyrP F uracil Permease
GHHKAJPP_00522 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GHHKAJPP_00523 3.5e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
GHHKAJPP_00524 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
GHHKAJPP_00525 1.2e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
GHHKAJPP_00526 1.5e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHHKAJPP_00527 1.2e-121 macB V ABC transporter, ATP-binding protein
GHHKAJPP_00528 1.4e-202 V permease protein
GHHKAJPP_00529 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GHHKAJPP_00530 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GHHKAJPP_00533 9.7e-231 2.7.13.3 T GHKL domain
GHHKAJPP_00534 5.9e-132 agrA KT Response regulator of the LytR AlgR family
GHHKAJPP_00536 1.3e-20 S Antitoxin component of a toxin-antitoxin (TA) module
GHHKAJPP_00537 6.2e-30 XK27_00530 M CHAP domain protein
GHHKAJPP_00538 1.7e-102 abiGI K Transcriptional regulator, AbiEi antitoxin
GHHKAJPP_00539 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GHHKAJPP_00540 4.6e-29 K DNA-binding transcription factor activity
GHHKAJPP_00541 0.0 mdlB V abc transporter atp-binding protein
GHHKAJPP_00542 0.0 lmrA V abc transporter atp-binding protein
GHHKAJPP_00543 7.8e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GHHKAJPP_00544 1.2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GHHKAJPP_00545 2.8e-52 S Protein conserved in bacteria
GHHKAJPP_00546 6.9e-197 yceA S Belongs to the UPF0176 family
GHHKAJPP_00547 1.6e-28 XK27_00085 K Transcriptional
GHHKAJPP_00548 7.4e-22
GHHKAJPP_00549 1.1e-133 deoD_1 2.4.2.3 F Phosphorylase superfamily
GHHKAJPP_00550 2.3e-114 S VIT family
GHHKAJPP_00551 9.4e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHHKAJPP_00552 1.3e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GHHKAJPP_00553 6.2e-194 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GHHKAJPP_00555 4.1e-131 E Alpha beta hydrolase
GHHKAJPP_00556 8e-49 T peptidase
GHHKAJPP_00557 2.2e-109 T Response regulator receiver domain protein
GHHKAJPP_00558 2.1e-180 ybdK T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GHHKAJPP_00559 6.7e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHHKAJPP_00560 3.5e-07 pepV 3.5.1.18 E Peptidase family M20/M25/M40
GHHKAJPP_00561 1.1e-97 ET Bacterial extracellular solute-binding proteins, family 3
GHHKAJPP_00562 2.5e-59 K Acetyltransferase (GNAT) domain
GHHKAJPP_00564 3e-152 1.8.5.7 O Glutathione S-transferase
GHHKAJPP_00565 9.5e-173 1.8.5.7 O Glutathione S-transferase, C-terminal domain
GHHKAJPP_00566 5.7e-134 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GHHKAJPP_00567 3.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GHHKAJPP_00568 4.1e-165 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GHHKAJPP_00569 7.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHHKAJPP_00570 6.6e-148 V ABC transporter, ATP-binding protein
GHHKAJPP_00571 1.9e-50 S ABC-2 family transporter protein
GHHKAJPP_00572 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GHHKAJPP_00573 9.6e-245 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHHKAJPP_00574 1.6e-94 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
GHHKAJPP_00575 9.2e-24
GHHKAJPP_00576 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GHHKAJPP_00577 0.0 U protein secretion
GHHKAJPP_00578 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
GHHKAJPP_00579 5.7e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GHHKAJPP_00581 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHHKAJPP_00582 2.1e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GHHKAJPP_00583 4.2e-192 S Protein of unknown function (DUF3114)
GHHKAJPP_00584 4.1e-29 pspC KT PspC domain protein
GHHKAJPP_00585 1.2e-118 yqfA K protein, Hemolysin III
GHHKAJPP_00586 3e-78 K hmm pf08876
GHHKAJPP_00587 2.9e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GHHKAJPP_00588 1.6e-208 mvaS 2.3.3.10 I synthase
GHHKAJPP_00589 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GHHKAJPP_00590 1.2e-88 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GHHKAJPP_00591 9.7e-22
GHHKAJPP_00592 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GHHKAJPP_00593 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
GHHKAJPP_00594 8.3e-249 mmuP E amino acid
GHHKAJPP_00595 1.3e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
GHHKAJPP_00596 2.2e-30 S Domain of unknown function (DUF1912)
GHHKAJPP_00597 6.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
GHHKAJPP_00598 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHHKAJPP_00599 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHHKAJPP_00601 1e-08
GHHKAJPP_00602 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHHKAJPP_00603 1.7e-198 ilvE 2.6.1.42 E Aminotransferase
GHHKAJPP_00604 2.8e-16 S Protein of unknown function (DUF2969)
GHHKAJPP_00607 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
GHHKAJPP_00610 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
GHHKAJPP_00611 1.4e-116 M Pfam SNARE associated Golgi protein
GHHKAJPP_00612 5e-229 murN 2.3.2.16 V FemAB family
GHHKAJPP_00613 5.8e-172 S oxidoreductase
GHHKAJPP_00614 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
GHHKAJPP_00615 1.1e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GHHKAJPP_00616 0.0 clpE O Belongs to the ClpA ClpB family
GHHKAJPP_00617 1.8e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GHHKAJPP_00618 1e-34 ykuJ S protein conserved in bacteria
GHHKAJPP_00619 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
GHHKAJPP_00620 9.3e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
GHHKAJPP_00621 1.6e-77 feoA P FeoA domain protein
GHHKAJPP_00622 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GHHKAJPP_00623 5e-08
GHHKAJPP_00624 5.2e-147 I Alpha/beta hydrolase family
GHHKAJPP_00625 4.8e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHHKAJPP_00626 4.4e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHHKAJPP_00627 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
GHHKAJPP_00628 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GHHKAJPP_00629 6.2e-146 licT K antiterminator
GHHKAJPP_00630 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHHKAJPP_00631 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GHHKAJPP_00632 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GHHKAJPP_00633 2.2e-143 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GHHKAJPP_00634 1.1e-91 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GHHKAJPP_00635 2.7e-222 mdtG EGP Major facilitator Superfamily
GHHKAJPP_00636 2e-33 secG U Preprotein translocase subunit SecG
GHHKAJPP_00637 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GHHKAJPP_00638 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GHHKAJPP_00639 2.8e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHHKAJPP_00640 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
GHHKAJPP_00641 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
GHHKAJPP_00642 2.4e-181 ccpA K Catabolite control protein A
GHHKAJPP_00643 3.6e-199 yyaQ S YjbR
GHHKAJPP_00644 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GHHKAJPP_00645 3.1e-75 yueI S Protein of unknown function (DUF1694)
GHHKAJPP_00646 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHHKAJPP_00647 1.2e-25 WQ51_00785
GHHKAJPP_00648 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GHHKAJPP_00649 3.8e-218 ywbD 2.1.1.191 J Methyltransferase
GHHKAJPP_00650 7.5e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GHHKAJPP_00651 2.2e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GHHKAJPP_00652 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GHHKAJPP_00653 1.9e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GHHKAJPP_00654 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GHHKAJPP_00655 4.2e-53 yheA S Belongs to the UPF0342 family
GHHKAJPP_00656 5.5e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GHHKAJPP_00657 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GHHKAJPP_00658 2.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GHHKAJPP_00659 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
GHHKAJPP_00660 3.5e-242 msrR K Transcriptional regulator
GHHKAJPP_00661 2.7e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
GHHKAJPP_00662 1.6e-199 I acyl-CoA dehydrogenase
GHHKAJPP_00663 2e-97 mip S hydroperoxide reductase activity
GHHKAJPP_00664 1.1e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHHKAJPP_00665 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
GHHKAJPP_00666 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
GHHKAJPP_00667 1.6e-61 smtB K Transcriptional regulator
GHHKAJPP_00668 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GHHKAJPP_00669 4.3e-22
GHHKAJPP_00670 2e-217 EGP Transmembrane secretion effector
GHHKAJPP_00671 4.2e-259 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
GHHKAJPP_00672 1.1e-49
GHHKAJPP_00673 8.7e-60
GHHKAJPP_00674 5.9e-55
GHHKAJPP_00675 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHHKAJPP_00676 5.7e-112 K Bacterial regulatory proteins, tetR family
GHHKAJPP_00677 2.9e-115 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
GHHKAJPP_00678 7.9e-129 bcrA V abc transporter atp-binding protein
GHHKAJPP_00679 7.7e-297 V ABC transporter transmembrane region
GHHKAJPP_00680 1.7e-12
GHHKAJPP_00681 1.8e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GHHKAJPP_00682 5.8e-132 S Domain of unknown function (DUF4336)
GHHKAJPP_00683 7e-204 yeaN P transporter
GHHKAJPP_00684 7.8e-149 yitS S EDD domain protein, DegV family
GHHKAJPP_00685 2.9e-94 XK27_08140 K Bacterial regulatory proteins, tetR family
GHHKAJPP_00686 2.5e-107 cutC P Participates in the control of copper homeostasis
GHHKAJPP_00688 7.1e-21 S Domain of unknown function (DUF4767)
GHHKAJPP_00689 3e-283 norB P Major facilitator superfamily
GHHKAJPP_00690 6.3e-91 tetR K transcriptional regulator
GHHKAJPP_00691 8.3e-151 S Domain of unknown function (DUF4300)
GHHKAJPP_00692 2.5e-114 V CAAX protease self-immunity
GHHKAJPP_00693 4.6e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GHHKAJPP_00694 1.6e-132 fecE 3.6.3.34 HP ABC transporter
GHHKAJPP_00695 2.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GHHKAJPP_00696 3.8e-125 ybbA S Putative esterase
GHHKAJPP_00697 7.4e-158 yegS 2.7.1.107 I Diacylglycerol kinase
GHHKAJPP_00698 5.2e-171 S Domain of unknown function (DUF389)
GHHKAJPP_00699 5.5e-31 S Membrane
GHHKAJPP_00700 1.1e-11 S Belongs to the UPF0337 (CsbD) family
GHHKAJPP_00701 3.5e-46
GHHKAJPP_00702 6.8e-11
GHHKAJPP_00703 2.1e-17 M Bacterial lipoprotein
GHHKAJPP_00704 6.4e-61 S Protein of unknown function (DUF1722)
GHHKAJPP_00705 2.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
GHHKAJPP_00707 5.5e-51
GHHKAJPP_00708 1.9e-88 S CAAX protease self-immunity
GHHKAJPP_00709 6.2e-114 estA E GDSL-like Lipase/Acylhydrolase
GHHKAJPP_00710 1.4e-99
GHHKAJPP_00711 2.1e-275 sulP P Sulfate permease and related transporters (MFS superfamily)
GHHKAJPP_00712 8.4e-148 ycgQ S TIGR03943 family
GHHKAJPP_00713 1.6e-155 XK27_03015 S permease
GHHKAJPP_00715 0.0 yhgF K Transcriptional accessory protein
GHHKAJPP_00716 2.4e-40 pspC KT PspC domain
GHHKAJPP_00717 7e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GHHKAJPP_00718 1.1e-141 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GHHKAJPP_00719 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GHHKAJPP_00720 7.4e-66 ytxH S General stress protein
GHHKAJPP_00722 6.8e-178 yegQ O Peptidase U32
GHHKAJPP_00723 7.5e-252 yegQ O Peptidase U32
GHHKAJPP_00724 5.5e-87 bioY S biotin synthase
GHHKAJPP_00726 1.1e-33 XK27_12190 S protein conserved in bacteria
GHHKAJPP_00727 1.1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
GHHKAJPP_00728 2.3e-13
GHHKAJPP_00729 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
GHHKAJPP_00730 0.0 L helicase
GHHKAJPP_00731 9.6e-15
GHHKAJPP_00732 2.7e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GHHKAJPP_00733 3.7e-137 M LysM domain
GHHKAJPP_00734 8.4e-23
GHHKAJPP_00735 1.2e-174 S hydrolase
GHHKAJPP_00737 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
GHHKAJPP_00738 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHHKAJPP_00739 8.4e-141 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
GHHKAJPP_00740 7e-27 P Hemerythrin HHE cation binding domain protein
GHHKAJPP_00741 2.7e-157 5.2.1.8 G hydrolase
GHHKAJPP_00742 6.7e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GHHKAJPP_00743 2.5e-198 MA20_36090 S Protein of unknown function (DUF2974)
GHHKAJPP_00744 8.4e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GHHKAJPP_00745 4.4e-45 S Phage derived protein Gp49-like (DUF891)
GHHKAJPP_00746 3.8e-45 K Helix-turn-helix domain
GHHKAJPP_00747 4.7e-41 S Nucleotide pyrophosphohydrolase
GHHKAJPP_00748 1.2e-188 L Uncharacterized conserved protein (DUF2075)
GHHKAJPP_00749 2.4e-135 S double-stranded DNA endodeoxyribonuclease activity
GHHKAJPP_00750 0.0 2.4.1.21 GT5 M Right handed beta helix region
GHHKAJPP_00751 6.6e-171 spd F DNA RNA non-specific endonuclease
GHHKAJPP_00752 7.7e-92 lemA S LemA family
GHHKAJPP_00753 1.3e-133 htpX O Belongs to the peptidase M48B family
GHHKAJPP_00754 4.1e-113 sirR K iron dependent repressor
GHHKAJPP_00755 5.4e-167 sitA P Belongs to the bacterial solute-binding protein 9 family
GHHKAJPP_00756 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
GHHKAJPP_00757 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
GHHKAJPP_00758 4.7e-74 S Psort location CytoplasmicMembrane, score
GHHKAJPP_00759 8.1e-64 S Domain of unknown function (DUF4430)
GHHKAJPP_00760 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHHKAJPP_00761 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
GHHKAJPP_00762 6.1e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
GHHKAJPP_00763 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
GHHKAJPP_00764 1.2e-99 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GHHKAJPP_00765 4.5e-78 dps P Belongs to the Dps family
GHHKAJPP_00766 3.8e-78 perR P Belongs to the Fur family
GHHKAJPP_00767 7.1e-27 yqgQ S protein conserved in bacteria
GHHKAJPP_00768 1.9e-178 glk 2.7.1.2 G Glucokinase
GHHKAJPP_00769 0.0 typA T GTP-binding protein TypA
GHHKAJPP_00771 1.7e-246 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GHHKAJPP_00772 3.1e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GHHKAJPP_00773 1.3e-135 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GHHKAJPP_00774 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GHHKAJPP_00775 4.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHHKAJPP_00776 2.8e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GHHKAJPP_00777 1.1e-93 sepF D cell septum assembly
GHHKAJPP_00778 1.7e-30 yggT D integral membrane protein
GHHKAJPP_00779 2.9e-137 ylmH S conserved protein, contains S4-like domain
GHHKAJPP_00780 1.9e-137 divIVA D Cell division initiation protein
GHHKAJPP_00781 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GHHKAJPP_00782 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHHKAJPP_00783 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHHKAJPP_00784 6.5e-34 nrdH O Glutaredoxin
GHHKAJPP_00785 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GHHKAJPP_00786 2.4e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
GHHKAJPP_00787 7.7e-219 icd 1.1.1.42 C Isocitrate dehydrogenase
GHHKAJPP_00788 3e-38 ptsH G phosphocarrier protein Hpr
GHHKAJPP_00789 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHHKAJPP_00790 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
GHHKAJPP_00791 4.3e-160 XK27_05670 S Putative esterase
GHHKAJPP_00792 2.7e-153 XK27_05675 S Esterase
GHHKAJPP_00793 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
GHHKAJPP_00794 6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
GHHKAJPP_00795 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GHHKAJPP_00796 0.0 uup S abc transporter atp-binding protein
GHHKAJPP_00797 2.7e-39 MA20_06245 S yiaA/B two helix domain
GHHKAJPP_00798 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
GHHKAJPP_00799 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHHKAJPP_00800 8.1e-148 cobQ S glutamine amidotransferase
GHHKAJPP_00801 8.4e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
GHHKAJPP_00802 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GHHKAJPP_00803 3.2e-162 ybbR S Protein conserved in bacteria
GHHKAJPP_00804 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHHKAJPP_00805 1.8e-66 gtrA S GtrA-like protein
GHHKAJPP_00806 3.7e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
GHHKAJPP_00807 1.3e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GHHKAJPP_00808 1.1e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
GHHKAJPP_00809 5.1e-193 yurR 1.4.5.1 E oxidoreductase
GHHKAJPP_00810 9e-256 S phospholipase Carboxylesterase
GHHKAJPP_00811 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GHHKAJPP_00812 1.4e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GHHKAJPP_00813 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GHHKAJPP_00815 2.2e-30 KT response to antibiotic
GHHKAJPP_00816 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
GHHKAJPP_00817 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
GHHKAJPP_00818 8.8e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GHHKAJPP_00819 6e-117 ylfI S tigr01906
GHHKAJPP_00820 2.8e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
GHHKAJPP_00821 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
GHHKAJPP_00822 2.1e-59 XK27_08085
GHHKAJPP_00823 1.8e-190 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GHHKAJPP_00824 4.8e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GHHKAJPP_00825 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GHHKAJPP_00826 3.9e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GHHKAJPP_00827 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GHHKAJPP_00828 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GHHKAJPP_00829 7.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GHHKAJPP_00830 4.7e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GHHKAJPP_00831 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GHHKAJPP_00832 1.2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
GHHKAJPP_00834 3.8e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
GHHKAJPP_00835 5.9e-143 P molecular chaperone
GHHKAJPP_00836 2.8e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
GHHKAJPP_00837 7.2e-181 XK27_08075 M glycosyl transferase family 2
GHHKAJPP_00838 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_00839 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_00840 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_00841 2.9e-228 rodA D Belongs to the SEDS family
GHHKAJPP_00842 9.2e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHHKAJPP_00843 1.4e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GHHKAJPP_00844 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GHHKAJPP_00845 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GHHKAJPP_00846 7.5e-21 Q Methyltransferase domain
GHHKAJPP_00847 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
GHHKAJPP_00848 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
GHHKAJPP_00849 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GHHKAJPP_00850 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GHHKAJPP_00851 1.3e-125 dnaD
GHHKAJPP_00852 4.2e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHHKAJPP_00854 1.4e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHHKAJPP_00855 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHHKAJPP_00856 3.4e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GHHKAJPP_00857 9.4e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GHHKAJPP_00858 8.3e-73 argR K Regulates arginine biosynthesis genes
GHHKAJPP_00859 1.2e-294 recN L May be involved in recombinational repair of damaged DNA
GHHKAJPP_00860 1.2e-144 DegV S DegV family
GHHKAJPP_00861 2.7e-152 ypmR E COG2755 Lysophospholipase L1 and related esterases
GHHKAJPP_00862 1.7e-94 ypmS S Protein conserved in bacteria
GHHKAJPP_00863 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GHHKAJPP_00865 6.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
GHHKAJPP_00866 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHHKAJPP_00867 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GHHKAJPP_00868 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GHHKAJPP_00869 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GHHKAJPP_00870 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GHHKAJPP_00871 0.0 dnaE 2.7.7.7 L DNA polymerase
GHHKAJPP_00872 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GHHKAJPP_00873 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GHHKAJPP_00874 2.9e-291 Q the current gene model (or a revised gene model) may contain a frame shift
GHHKAJPP_00875 1.7e-18 S Domain of unknown function (DUF4649)
GHHKAJPP_00876 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
GHHKAJPP_00877 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
GHHKAJPP_00878 8.9e-136 XK27_08845 S abc transporter atp-binding protein
GHHKAJPP_00879 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHHKAJPP_00880 3.6e-148 estA CE1 S Esterase
GHHKAJPP_00881 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
GHHKAJPP_00882 2.2e-18 XK27_08880
GHHKAJPP_00883 3.9e-75 fld C Flavodoxin
GHHKAJPP_00884 8.6e-279 clcA P Chloride transporter, ClC family
GHHKAJPP_00885 1.2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
GHHKAJPP_00886 2.9e-208 XK27_05110 P Chloride transporter ClC family
GHHKAJPP_00887 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GHHKAJPP_00890 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
GHHKAJPP_00891 1.1e-159 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GHHKAJPP_00892 3.1e-84 ytsP 1.8.4.14 T GAF domain-containing protein
GHHKAJPP_00893 2.1e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHHKAJPP_00894 2.8e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GHHKAJPP_00895 3.3e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GHHKAJPP_00896 2.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHHKAJPP_00897 3.6e-132
GHHKAJPP_00899 7.4e-247 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
GHHKAJPP_00900 1e-193 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
GHHKAJPP_00901 1.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHHKAJPP_00902 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
GHHKAJPP_00903 3.2e-153 endA F DNA RNA non-specific endonuclease
GHHKAJPP_00904 2.9e-111 tcyB_2 P ABC transporter (permease)
GHHKAJPP_00905 2.8e-115 gltJ P ABC transporter (Permease
GHHKAJPP_00906 6.4e-143 peb1A ET Belongs to the bacterial solute-binding protein 3 family
GHHKAJPP_00907 1.6e-109 tcyB_2 P ABC transporter (permease)
GHHKAJPP_00908 2.8e-115 gltJ P ABC transporter (Permease
GHHKAJPP_00909 5.6e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GHHKAJPP_00910 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GHHKAJPP_00911 6.7e-235 vicK 2.7.13.3 T Histidine kinase
GHHKAJPP_00912 1.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
GHHKAJPP_00913 1.3e-57 S Protein of unknown function (DUF454)
GHHKAJPP_00914 3.9e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
GHHKAJPP_00915 4.6e-146 yidA S hydrolases of the HAD superfamily
GHHKAJPP_00916 9.1e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
GHHKAJPP_00917 5.3e-68 ywiB S Domain of unknown function (DUF1934)
GHHKAJPP_00918 0.0 pacL 3.6.3.8 P cation transport ATPase
GHHKAJPP_00919 8.5e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GHHKAJPP_00920 2.1e-154 yjjH S Calcineurin-like phosphoesterase
GHHKAJPP_00921 1e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GHHKAJPP_00922 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHHKAJPP_00923 3.2e-124 ftsE D cell division ATP-binding protein FtsE
GHHKAJPP_00924 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GHHKAJPP_00925 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
GHHKAJPP_00926 4e-175 yubA S permease
GHHKAJPP_00927 9.5e-220 G COG0457 FOG TPR repeat
GHHKAJPP_00928 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHHKAJPP_00929 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GHHKAJPP_00930 2.2e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GHHKAJPP_00931 1.2e-85 ebsA S Family of unknown function (DUF5322)
GHHKAJPP_00932 9.4e-17 M LysM domain
GHHKAJPP_00933 3.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GHHKAJPP_00934 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GHHKAJPP_00935 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GHHKAJPP_00936 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GHHKAJPP_00937 1.1e-75 XK27_03610 K Gnat family
GHHKAJPP_00938 1.9e-89 yybC
GHHKAJPP_00939 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GHHKAJPP_00940 5e-273 pepV 3.5.1.18 E Dipeptidase
GHHKAJPP_00941 1.4e-107 ung2 3.2.2.27 L Uracil-DNA glycosylase
GHHKAJPP_00942 8.5e-227 V Glucan-binding protein C
GHHKAJPP_00943 8.2e-252 V Glucan-binding protein C
GHHKAJPP_00944 4e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GHHKAJPP_00945 7.9e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GHHKAJPP_00946 5e-96 S Protein of unknown function (DUF1697)
GHHKAJPP_00947 1.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GHHKAJPP_00948 3.8e-168 clcA_2 P chloride
GHHKAJPP_00949 1.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
GHHKAJPP_00950 8.4e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
GHHKAJPP_00951 8.3e-247 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
GHHKAJPP_00952 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
GHHKAJPP_00953 1.2e-110 cps4C M biosynthesis protein
GHHKAJPP_00954 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
GHHKAJPP_00955 1.2e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
GHHKAJPP_00956 9e-220 rgpAc GT4 M group 1 family protein
GHHKAJPP_00957 2e-211 wcoF M Glycosyltransferase, group 1 family protein
GHHKAJPP_00958 5.5e-43 Z012_10770 M Domain of unknown function (DUF1919)
GHHKAJPP_00959 4.1e-29 Z012_10770 M Domain of unknown function (DUF1919)
GHHKAJPP_00960 2.7e-169 M Glycosyltransferase, group 2 family protein
GHHKAJPP_00961 2.8e-153 M Glycosyltransferase like family 2
GHHKAJPP_00962 1.3e-173
GHHKAJPP_00963 7.8e-242 epsU S Polysaccharide biosynthesis protein
GHHKAJPP_00964 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
GHHKAJPP_00965 1.4e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
GHHKAJPP_00966 1.9e-184 wbbI M transferase activity, transferring glycosyl groups
GHHKAJPP_00968 4.8e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GHHKAJPP_00969 2e-106 pgm G Belongs to the phosphoglycerate mutase family
GHHKAJPP_00970 8.3e-108 G Belongs to the phosphoglycerate mutase family
GHHKAJPP_00971 8.1e-108 G Belongs to the phosphoglycerate mutase family
GHHKAJPP_00972 2.3e-196 S hmm pf01594
GHHKAJPP_00973 8.9e-286 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHHKAJPP_00974 4.1e-38 S granule-associated protein
GHHKAJPP_00975 2.3e-279 S unusual protein kinase
GHHKAJPP_00976 3.2e-99 estA E Lysophospholipase L1 and related esterases
GHHKAJPP_00977 7.7e-152 rssA S Phospholipase, patatin family
GHHKAJPP_00978 3e-179 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GHHKAJPP_00979 3.2e-245 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GHHKAJPP_00980 1.7e-213 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GHHKAJPP_00981 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GHHKAJPP_00982 3.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHHKAJPP_00983 2.3e-300 S the current gene model (or a revised gene model) may contain a frame shift
GHHKAJPP_00984 9.3e-226 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_00985 2.1e-198 hpk9 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_00986 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GHHKAJPP_00987 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GHHKAJPP_00988 4.8e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GHHKAJPP_00989 1.1e-306 lpdA 1.8.1.4 C Dehydrogenase
GHHKAJPP_00990 0.0 3.5.1.28 NU amidase activity
GHHKAJPP_00991 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
GHHKAJPP_00992 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GHHKAJPP_00993 2.2e-146 ycdO P periplasmic lipoprotein involved in iron transport
GHHKAJPP_00994 5.8e-230 ycdB P peroxidase
GHHKAJPP_00995 5.3e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
GHHKAJPP_00996 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GHHKAJPP_00997 1.9e-23 tatA U protein secretion
GHHKAJPP_00998 1.1e-211 msmX P Belongs to the ABC transporter superfamily
GHHKAJPP_00999 2.2e-151 malG P ABC transporter (Permease
GHHKAJPP_01000 2.2e-249 malF P ABC transporter (Permease
GHHKAJPP_01001 1.1e-228 malX G ABC transporter
GHHKAJPP_01002 7.9e-156 malR K Transcriptional regulator
GHHKAJPP_01003 3.6e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
GHHKAJPP_01004 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GHHKAJPP_01005 8.9e-39
GHHKAJPP_01006 8e-185 lplA 6.3.1.20 H Lipoate-protein ligase
GHHKAJPP_01007 2.5e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GHHKAJPP_01008 0.0 pepN 3.4.11.2 E aminopeptidase
GHHKAJPP_01009 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
GHHKAJPP_01010 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHHKAJPP_01011 3.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHHKAJPP_01012 9.1e-156 pstA P phosphate transport system permease
GHHKAJPP_01013 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
GHHKAJPP_01014 4.5e-155 pstS P phosphate
GHHKAJPP_01015 1.5e-244 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GHHKAJPP_01016 3.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GHHKAJPP_01017 1e-44 yktA S Belongs to the UPF0223 family
GHHKAJPP_01018 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GHHKAJPP_01019 8.7e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GHHKAJPP_01020 5.5e-153 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GHHKAJPP_01021 1.6e-233 XK27_04775 S hemerythrin HHE cation binding domain
GHHKAJPP_01022 4.7e-35 M1-755 P Hemerythrin HHE cation binding domain protein
GHHKAJPP_01023 2.1e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
GHHKAJPP_01024 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GHHKAJPP_01025 2.6e-135 S haloacid dehalogenase-like hydrolase
GHHKAJPP_01026 2.9e-227 metY 2.5.1.49 E o-acetylhomoserine
GHHKAJPP_01027 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GHHKAJPP_01028 3.4e-239 agcS E (Alanine) symporter
GHHKAJPP_01029 4.4e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GHHKAJPP_01030 2.4e-170 bglC K Transcriptional regulator
GHHKAJPP_01031 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
GHHKAJPP_01032 9.3e-81 yecS P ABC transporter (Permease
GHHKAJPP_01033 4.6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
GHHKAJPP_01034 6.1e-242 nylA 3.5.1.4 J Belongs to the amidase family
GHHKAJPP_01035 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHHKAJPP_01036 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GHHKAJPP_01037 6.5e-103
GHHKAJPP_01038 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GHHKAJPP_01039 2.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GHHKAJPP_01040 6.1e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
GHHKAJPP_01041 8e-135 S TraX protein
GHHKAJPP_01042 1.5e-305 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GHHKAJPP_01043 2.1e-277 S Psort location CytoplasmicMembrane, score
GHHKAJPP_01044 3.4e-231 dinF V Mate efflux family protein
GHHKAJPP_01045 6.6e-176 yclQ P ABC-type enterochelin transport system, periplasmic component
GHHKAJPP_01046 0.0 V Type III restriction enzyme, res subunit
GHHKAJPP_01047 6e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
GHHKAJPP_01048 7.9e-140 2.4.2.3 F Phosphorylase superfamily
GHHKAJPP_01049 1.5e-109 K Bacterial regulatory proteins, tetR family
GHHKAJPP_01050 1.8e-177 ybhR V ABC transporter
GHHKAJPP_01051 5.7e-124 ybhF_2 V abc transporter atp-binding protein
GHHKAJPP_01054 4.9e-138 G protein with an alpha beta hydrolase fold
GHHKAJPP_01055 1.1e-85 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GHHKAJPP_01056 0.0 copA 3.6.3.54 P P-type ATPase
GHHKAJPP_01057 4.8e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GHHKAJPP_01058 1.4e-63 copY K Copper transport repressor, CopY TcrY family
GHHKAJPP_01059 1.9e-189 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GHHKAJPP_01060 1.8e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GHHKAJPP_01061 5.2e-151 czcD P cation diffusion facilitator family transporter
GHHKAJPP_01062 1e-99 K Transcriptional regulator, TetR family
GHHKAJPP_01063 1.6e-58 S Protein of unknown function with HXXEE motif
GHHKAJPP_01064 1.7e-38
GHHKAJPP_01065 2.1e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GHHKAJPP_01066 1.6e-154 I Alpha/beta hydrolase family
GHHKAJPP_01067 3.9e-179 1.1.1.1 C nadph quinone reductase
GHHKAJPP_01068 4e-64 K Transcriptional regulator
GHHKAJPP_01069 2.7e-61 pnuC H nicotinamide mononucleotide transporter
GHHKAJPP_01070 3.9e-150 cbiO2 P ABC transporter, ATP-binding protein
GHHKAJPP_01071 1.7e-156 P ATPase activity
GHHKAJPP_01072 4.4e-133 cbiQ P cobalt transport
GHHKAJPP_01073 4.8e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
GHHKAJPP_01074 1.5e-138 S Phenazine biosynthesis protein
GHHKAJPP_01075 5.7e-92 tetR K transcriptional regulator
GHHKAJPP_01076 1.9e-124 V abc transporter atp-binding protein
GHHKAJPP_01077 0.0 V ABC transporter (Permease
GHHKAJPP_01078 3.7e-35 L Integrase core domain protein
GHHKAJPP_01079 2e-109 magIII L Base excision DNA repair protein, HhH-GPD family
GHHKAJPP_01080 8.6e-263 proWX P ABC transporter
GHHKAJPP_01081 7e-130 proV E abc transporter atp-binding protein
GHHKAJPP_01082 8.6e-168 C alcohol dehydrogenase
GHHKAJPP_01083 2.2e-135 1.6.5.2 GM NmrA-like family
GHHKAJPP_01084 8.9e-67 mgrA K Transcriptional regulator, MarR family
GHHKAJPP_01085 8.8e-78 S Macro domain
GHHKAJPP_01086 2.4e-94 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GHHKAJPP_01087 2.6e-39 C Pyridoxamine 5'-phosphate oxidase
GHHKAJPP_01088 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GHHKAJPP_01089 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GHHKAJPP_01092 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHHKAJPP_01094 8.2e-137 IQ Acetoin reductase
GHHKAJPP_01095 4.8e-45 pspE P Rhodanese-like protein
GHHKAJPP_01096 5.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GHHKAJPP_01097 1e-223 XK27_05470 E Methionine synthase
GHHKAJPP_01098 2.4e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GHHKAJPP_01099 3.2e-221 T PhoQ Sensor
GHHKAJPP_01100 5.1e-119 KT Transcriptional regulatory protein, C terminal
GHHKAJPP_01101 2.1e-146 S TraX protein
GHHKAJPP_01103 2.6e-52 V ABC-2 family transporter protein
GHHKAJPP_01104 2.1e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
GHHKAJPP_01105 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHHKAJPP_01106 7e-158 dprA LU DNA protecting protein DprA
GHHKAJPP_01107 1.4e-162 GK ROK family
GHHKAJPP_01108 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHHKAJPP_01109 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GHHKAJPP_01110 5.3e-127 K DNA-binding helix-turn-helix protein
GHHKAJPP_01111 1.9e-89 niaR S small molecule binding protein (contains 3H domain)
GHHKAJPP_01112 1.6e-86
GHHKAJPP_01113 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHHKAJPP_01114 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GHHKAJPP_01115 2.7e-126 gntR1 K transcriptional
GHHKAJPP_01116 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GHHKAJPP_01117 8.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GHHKAJPP_01118 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
GHHKAJPP_01119 1e-44
GHHKAJPP_01120 2.6e-51
GHHKAJPP_01121 8.5e-265 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHHKAJPP_01122 6.7e-156 aatB ET ABC transporter substrate-binding protein
GHHKAJPP_01123 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
GHHKAJPP_01124 9e-105 artQ P ABC transporter (Permease
GHHKAJPP_01125 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
GHHKAJPP_01126 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHHKAJPP_01127 8.4e-165 cpsY K Transcriptional regulator
GHHKAJPP_01128 3.5e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
GHHKAJPP_01129 1.9e-170 yeiH S Membrane
GHHKAJPP_01131 2.6e-09
GHHKAJPP_01132 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
GHHKAJPP_01133 1.1e-142 XK27_10720 D peptidase activity
GHHKAJPP_01134 2.2e-273 pepD E Dipeptidase
GHHKAJPP_01135 2.2e-160 whiA K May be required for sporulation
GHHKAJPP_01136 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GHHKAJPP_01137 5.5e-161 rapZ S Displays ATPase and GTPase activities
GHHKAJPP_01138 3.8e-134 yejC S cyclic nucleotide-binding protein
GHHKAJPP_01139 2.2e-202 D nuclear chromosome segregation
GHHKAJPP_01140 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GHHKAJPP_01141 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GHHKAJPP_01142 8.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
GHHKAJPP_01143 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GHHKAJPP_01144 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
GHHKAJPP_01145 4.8e-19
GHHKAJPP_01146 9.3e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GHHKAJPP_01147 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GHHKAJPP_01148 3e-76 ypmB S Protein conserved in bacteria
GHHKAJPP_01149 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GHHKAJPP_01150 2.7e-117 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GHHKAJPP_01151 8.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
GHHKAJPP_01152 6.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
GHHKAJPP_01153 4.6e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GHHKAJPP_01154 1.8e-190 tcsA S membrane
GHHKAJPP_01155 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GHHKAJPP_01156 2.1e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHHKAJPP_01157 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GHHKAJPP_01158 5.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
GHHKAJPP_01159 5.6e-172 coaA 2.7.1.33 F Pantothenic acid kinase
GHHKAJPP_01160 1e-29 rpsT J Binds directly to 16S ribosomal RNA
GHHKAJPP_01161 9.8e-237 T PhoQ Sensor
GHHKAJPP_01162 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GHHKAJPP_01163 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GHHKAJPP_01164 7.1e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
GHHKAJPP_01165 9.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GHHKAJPP_01166 4.1e-93 panT S ECF transporter, substrate-specific component
GHHKAJPP_01167 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GHHKAJPP_01168 3.8e-162 metF 1.5.1.20 E reductase
GHHKAJPP_01169 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GHHKAJPP_01171 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
GHHKAJPP_01172 0.0 3.6.3.8 P cation transport ATPase
GHHKAJPP_01173 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GHHKAJPP_01174 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHHKAJPP_01175 1.2e-235 dltB M Membrane protein involved in D-alanine export
GHHKAJPP_01176 1.2e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHHKAJPP_01177 0.0 XK27_10035 V abc transporter atp-binding protein
GHHKAJPP_01178 5.5e-290 yfiB1 V abc transporter atp-binding protein
GHHKAJPP_01179 1.4e-99 pvaA M lytic transglycosylase activity
GHHKAJPP_01180 3.8e-179 ndpA S 37-kD nucleoid-associated bacterial protein
GHHKAJPP_01181 8.1e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GHHKAJPP_01182 1.1e-101 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GHHKAJPP_01183 1.2e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GHHKAJPP_01184 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHHKAJPP_01185 3e-110 tdk 2.7.1.21 F thymidine kinase
GHHKAJPP_01186 7.6e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GHHKAJPP_01187 2.7e-151 gst O Glutathione S-transferase
GHHKAJPP_01188 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
GHHKAJPP_01189 6.8e-170 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHHKAJPP_01190 4.4e-45 rpmE2 J 50S ribosomal protein L31
GHHKAJPP_01191 5.7e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
GHHKAJPP_01192 7.9e-161 ypuA S secreted protein
GHHKAJPP_01193 4.5e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
GHHKAJPP_01194 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
GHHKAJPP_01195 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHHKAJPP_01196 2.2e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHHKAJPP_01197 1.1e-253 noxE P NADH oxidase
GHHKAJPP_01198 1.1e-294 yfmM S abc transporter atp-binding protein
GHHKAJPP_01199 6.8e-82 XK27_01265 S ECF-type riboflavin transporter, S component
GHHKAJPP_01200 2.6e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
GHHKAJPP_01201 6.3e-85 S ECF-type riboflavin transporter, S component
GHHKAJPP_01203 6.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GHHKAJPP_01204 1.2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
GHHKAJPP_01206 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHHKAJPP_01207 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GHHKAJPP_01208 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GHHKAJPP_01209 7.3e-20 WQ51_00220 K Helix-turn-helix domain
GHHKAJPP_01210 5.9e-89 S Protein of unknown function (DUF3278)
GHHKAJPP_01211 0.0 smc D Required for chromosome condensation and partitioning
GHHKAJPP_01212 9.3e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHHKAJPP_01213 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHHKAJPP_01214 2.8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHHKAJPP_01215 8.8e-124 alkD L DNA alkylation repair enzyme
GHHKAJPP_01216 9.1e-292 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHHKAJPP_01217 6.3e-93 pat 2.3.1.183 M acetyltransferase
GHHKAJPP_01218 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHHKAJPP_01219 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GHHKAJPP_01220 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GHHKAJPP_01221 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHHKAJPP_01222 1.7e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
GHHKAJPP_01223 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
GHHKAJPP_01224 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
GHHKAJPP_01225 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
GHHKAJPP_01226 2.3e-162 yjlA EG membrane
GHHKAJPP_01227 3.6e-80 3.4.21.89 S RDD family
GHHKAJPP_01228 9.8e-49
GHHKAJPP_01229 2.8e-88
GHHKAJPP_01230 2.2e-22
GHHKAJPP_01231 2.2e-76 K Acetyltransferase (GNAT) domain
GHHKAJPP_01232 2.5e-141 S ABC-2 family transporter protein
GHHKAJPP_01233 1.1e-139 S ABC-2 family transporter protein
GHHKAJPP_01234 3.2e-186 S abc transporter atp-binding protein
GHHKAJPP_01235 3e-86 L COG1943 Transposase and inactivated derivatives
GHHKAJPP_01236 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GHHKAJPP_01237 9.4e-179 desK 2.7.13.3 T Histidine kinase
GHHKAJPP_01238 1.5e-132 yvfS V ABC-2 type transporter
GHHKAJPP_01239 7.9e-160 XK27_09825 V abc transporter atp-binding protein
GHHKAJPP_01242 6.2e-171 fabH 2.3.1.180 I synthase III
GHHKAJPP_01243 3.6e-238 6.2.1.30 H Coenzyme F390 synthetase
GHHKAJPP_01244 6e-154 gumP S Metallo-beta-lactamase superfamily
GHHKAJPP_01245 7.6e-180 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
GHHKAJPP_01246 5.6e-231 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
GHHKAJPP_01247 5.1e-94 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GHHKAJPP_01248 2e-171 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
GHHKAJPP_01249 1.2e-91
GHHKAJPP_01250 1.6e-209 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
GHHKAJPP_01252 4.9e-201 anK3 G response to abiotic stimulus
GHHKAJPP_01253 0.0 hscC O Belongs to the heat shock protein 70 family
GHHKAJPP_01254 3e-165 yocS S Transporter
GHHKAJPP_01255 2.2e-81 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
GHHKAJPP_01256 1.6e-118 yvfS V Transporter
GHHKAJPP_01257 3.2e-153 XK27_09825 V abc transporter atp-binding protein
GHHKAJPP_01258 1.4e-15 liaI KT membrane
GHHKAJPP_01259 2.2e-29 liaI KT membrane
GHHKAJPP_01260 6.1e-93 XK27_05000 S metal cluster binding
GHHKAJPP_01261 0.0 V ABC transporter (permease)
GHHKAJPP_01262 1.3e-131 macB2 V ABC transporter, ATP-binding protein
GHHKAJPP_01263 3.1e-149 T Histidine kinase
GHHKAJPP_01264 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GHHKAJPP_01265 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GHHKAJPP_01266 6.5e-224 pbuX F xanthine permease
GHHKAJPP_01267 6.7e-274 V (ABC) transporter
GHHKAJPP_01268 5.7e-144 K sequence-specific DNA binding
GHHKAJPP_01269 1.8e-243 norM V Multidrug efflux pump
GHHKAJPP_01271 1.2e-177 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GHHKAJPP_01272 7.8e-228 brnQ E Component of the transport system for branched-chain amino acids
GHHKAJPP_01273 7.8e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
GHHKAJPP_01274 1.8e-59 S Protein of unknown function (DUF3290)
GHHKAJPP_01275 3.4e-104 S Protein of unknown function (DUF421)
GHHKAJPP_01276 1.1e-16 csbD S CsbD-like
GHHKAJPP_01277 2e-115 S Carbohydrate-binding domain-containing protein Cthe_2159
GHHKAJPP_01279 1.6e-09 S Carbohydrate-binding domain-containing protein Cthe_2159
GHHKAJPP_01280 7.5e-50 XK27_01300 P Protein conserved in bacteria
GHHKAJPP_01281 1.8e-222 yfnA E amino acid
GHHKAJPP_01282 0.0 S dextransucrase activity
GHHKAJPP_01283 6.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GHHKAJPP_01284 1.5e-42 S Sugar efflux transporter for intercellular exchange
GHHKAJPP_01285 3e-204 P FtsX-like permease family
GHHKAJPP_01286 6e-123 V abc transporter atp-binding protein
GHHKAJPP_01287 1.1e-96 K WHG domain
GHHKAJPP_01288 7.5e-169 ydhF S Aldo keto reductase
GHHKAJPP_01289 4.9e-07 S Protein of unknown function (DUF3169)
GHHKAJPP_01290 2.5e-27 XK27_07105 K transcriptional
GHHKAJPP_01291 2.8e-35
GHHKAJPP_01292 8.7e-110 XK27_02070 S nitroreductase
GHHKAJPP_01293 2.2e-149 1.13.11.2 S glyoxalase
GHHKAJPP_01294 1.5e-74 ywnA K Transcriptional regulator
GHHKAJPP_01295 9.2e-153 E Alpha/beta hydrolase of unknown function (DUF915)
GHHKAJPP_01296 5.1e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHHKAJPP_01297 2.4e-110 drgA C nitroreductase
GHHKAJPP_01298 1.6e-104 yoaK S Protein of unknown function (DUF1275)
GHHKAJPP_01299 4e-40 DJ nuclease activity
GHHKAJPP_01300 1.9e-30 XK27_10490
GHHKAJPP_01301 3.2e-158 yvgN C reductase
GHHKAJPP_01302 1.6e-208 S Tetratricopeptide repeat
GHHKAJPP_01303 0.0 lacL 3.2.1.23 G -beta-galactosidase
GHHKAJPP_01304 0.0 lacS G transporter
GHHKAJPP_01305 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GHHKAJPP_01306 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GHHKAJPP_01307 9.8e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GHHKAJPP_01308 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GHHKAJPP_01309 3.2e-181 galR K Transcriptional regulator
GHHKAJPP_01310 1.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
GHHKAJPP_01311 7.9e-225 vncS 2.7.13.3 T Histidine kinase
GHHKAJPP_01312 2e-115 K Response regulator receiver domain protein
GHHKAJPP_01313 4.6e-239 vex3 V Efflux ABC transporter, permease protein
GHHKAJPP_01314 1e-108 vex2 V abc transporter atp-binding protein
GHHKAJPP_01315 7.8e-177 vex1 V Efflux ABC transporter, permease protein
GHHKAJPP_01316 1.5e-283 XK27_07020 S Belongs to the UPF0371 family
GHHKAJPP_01318 1.9e-195 gldA 1.1.1.6 C glycerol dehydrogenase
GHHKAJPP_01319 3e-176 XK27_10475 S oxidoreductase
GHHKAJPP_01320 8.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
GHHKAJPP_01321 9e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
GHHKAJPP_01322 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
GHHKAJPP_01323 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
GHHKAJPP_01324 0.0 M Putative cell wall binding repeat
GHHKAJPP_01325 2.4e-34 S Immunity protein 41
GHHKAJPP_01326 0.0 pepO 3.4.24.71 O Peptidase family M13
GHHKAJPP_01327 4.5e-07 S Enterocin A Immunity
GHHKAJPP_01328 1.6e-15 S integral membrane protein
GHHKAJPP_01329 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
GHHKAJPP_01330 5.7e-111 yhfC S Putative membrane peptidase family (DUF2324)
GHHKAJPP_01331 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_01333 4.1e-257 S dextransucrase activity
GHHKAJPP_01334 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_01335 0.0 S dextransucrase activity
GHHKAJPP_01336 0.0 S dextransucrase activity
GHHKAJPP_01337 0.0 S dextransucrase activity
GHHKAJPP_01338 4.7e-88 M Putative cell wall binding repeat
GHHKAJPP_01339 0.0 S dextransucrase activity
GHHKAJPP_01340 2.4e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GHHKAJPP_01341 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GHHKAJPP_01342 0.0 M Putative cell wall binding repeat
GHHKAJPP_01343 1.4e-302 S dextransucrase activity
GHHKAJPP_01344 3e-174 S dextransucrase activity
GHHKAJPP_01345 0.0 S dextransucrase activity
GHHKAJPP_01346 0.0 S dextransucrase activity
GHHKAJPP_01347 6.2e-226 S dextransucrase activity
GHHKAJPP_01349 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHHKAJPP_01350 4.8e-163 mleP S Sodium Bile acid symporter family
GHHKAJPP_01351 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
GHHKAJPP_01352 4.7e-47 K Helix-turn-helix
GHHKAJPP_01353 4.4e-118 mleR K malolactic fermentation system
GHHKAJPP_01354 3.9e-131 XK27_00785 S CAAX protease self-immunity
GHHKAJPP_01355 4.3e-237 EGP Major facilitator Superfamily
GHHKAJPP_01356 6.2e-67 rmaI K Transcriptional regulator, MarR family
GHHKAJPP_01357 9.7e-95 maa 2.3.1.79 GK Maltose O-acetyltransferase
GHHKAJPP_01358 1.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
GHHKAJPP_01359 0.0 3.5.1.28 M domain protein
GHHKAJPP_01360 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GHHKAJPP_01361 1.9e-24
GHHKAJPP_01368 1.1e-74 sraP UW Hep Hag repeat protein
GHHKAJPP_01369 0.0 sraP UW Hep Hag repeat protein
GHHKAJPP_01370 6.4e-190 nss M transferase activity, transferring glycosyl groups
GHHKAJPP_01371 3.6e-16 S Accessory secretory protein Sec, Asp5
GHHKAJPP_01372 2.6e-17 S Accessory secretory protein Sec Asp4
GHHKAJPP_01373 3.6e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GHHKAJPP_01374 5.9e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GHHKAJPP_01375 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHHKAJPP_01376 6.1e-76 asp3 S Accessory Sec system protein Asp3
GHHKAJPP_01377 6.4e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
GHHKAJPP_01378 3.2e-289 asp1 S Accessory Sec system protein Asp1
GHHKAJPP_01379 2.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GHHKAJPP_01380 0.0 M family 8
GHHKAJPP_01381 3.1e-34 S PFAM Uncharacterised protein family (UPF0153)
GHHKAJPP_01382 1.1e-142
GHHKAJPP_01383 0.0 sbcC L ATPase involved in DNA repair
GHHKAJPP_01384 3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GHHKAJPP_01385 0.0 GM domain, Protein
GHHKAJPP_01386 0.0 zmpB M signal peptide protein, YSIRK family
GHHKAJPP_01387 5.4e-267 fhaB M Rib/alpha-like repeat
GHHKAJPP_01388 0.0 M domain protein
GHHKAJPP_01389 2.9e-10
GHHKAJPP_01390 6.5e-186 XK27_10075 S abc transporter atp-binding protein
GHHKAJPP_01391 0.0 V abc transporter atp-binding protein
GHHKAJPP_01392 1.4e-296 V abc transporter atp-binding protein
GHHKAJPP_01393 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
GHHKAJPP_01395 1.7e-279 S Protein of unknown function (DUF3114)
GHHKAJPP_01396 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
GHHKAJPP_01397 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GHHKAJPP_01398 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
GHHKAJPP_01399 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
GHHKAJPP_01400 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GHHKAJPP_01401 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GHHKAJPP_01402 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GHHKAJPP_01403 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GHHKAJPP_01404 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GHHKAJPP_01405 7.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GHHKAJPP_01406 1.3e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GHHKAJPP_01409 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GHHKAJPP_01410 9.7e-170 vraS 2.7.13.3 T Histidine kinase
GHHKAJPP_01411 1.9e-116 yvqF S Membrane
GHHKAJPP_01412 7.9e-100 kcsA P Ion transport protein
GHHKAJPP_01413 2.6e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
GHHKAJPP_01414 2.6e-135 stp 3.1.3.16 T phosphatase
GHHKAJPP_01415 3.9e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GHHKAJPP_01416 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GHHKAJPP_01417 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHHKAJPP_01418 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
GHHKAJPP_01419 1.2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GHHKAJPP_01420 2.7e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHHKAJPP_01421 5.3e-142 XK27_02985 S overlaps another CDS with the same product name
GHHKAJPP_01422 1.4e-147 supH S overlaps another CDS with the same product name
GHHKAJPP_01423 1.9e-62 yvoA_1 K Transcriptional
GHHKAJPP_01424 5.4e-119 skfE V abc transporter atp-binding protein
GHHKAJPP_01425 9.9e-130 V Psort location CytoplasmicMembrane, score
GHHKAJPP_01426 3.1e-170 oppF P Belongs to the ABC transporter superfamily
GHHKAJPP_01427 1.3e-201 oppD P Belongs to the ABC transporter superfamily
GHHKAJPP_01428 3.5e-166 amiD P ABC transporter (Permease
GHHKAJPP_01429 2.1e-277 amiC P ABC transporter (Permease
GHHKAJPP_01430 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
GHHKAJPP_01431 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GHHKAJPP_01432 1.8e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GHHKAJPP_01433 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GHHKAJPP_01434 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GHHKAJPP_01435 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
GHHKAJPP_01436 2.4e-101 yjbK S Adenylate cyclase
GHHKAJPP_01437 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHHKAJPP_01438 2.3e-204 iscS 2.8.1.7 E Cysteine desulfurase
GHHKAJPP_01439 8.2e-60 XK27_04120 S Putative amino acid metabolism
GHHKAJPP_01440 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GHHKAJPP_01441 2.2e-128 puuD T peptidase C26
GHHKAJPP_01442 5.8e-118 radC E Belongs to the UPF0758 family
GHHKAJPP_01443 3.6e-168
GHHKAJPP_01444 6.9e-43 M Psort location CytoplasmicMembrane, score
GHHKAJPP_01445 1.6e-155 rfbJ M Glycosyl transferase family 2
GHHKAJPP_01446 0.0 rgpF M Rhamnan synthesis protein F
GHHKAJPP_01447 9.6e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GHHKAJPP_01448 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GHHKAJPP_01449 2e-141 rgpC GM Transport permease protein
GHHKAJPP_01450 1.5e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
GHHKAJPP_01451 2.5e-214 rgpA GT4 M Domain of unknown function (DUF1972)
GHHKAJPP_01452 1e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GHHKAJPP_01453 8e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GHHKAJPP_01454 7.6e-55 yitW K metal-sulfur cluster biosynthetic enzyme
GHHKAJPP_01455 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHHKAJPP_01456 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHHKAJPP_01457 4.2e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GHHKAJPP_01458 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GHHKAJPP_01459 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
GHHKAJPP_01460 4.9e-199 arcT 2.6.1.1 E Aminotransferase
GHHKAJPP_01461 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
GHHKAJPP_01462 2.2e-140 ET ABC transporter
GHHKAJPP_01463 1.8e-78 mutT 3.6.1.55 F Nudix family
GHHKAJPP_01464 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GHHKAJPP_01466 7.3e-164 S CAAX amino terminal protease family protein
GHHKAJPP_01467 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
GHHKAJPP_01468 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
GHHKAJPP_01469 1.7e-17 XK27_00735
GHHKAJPP_01470 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GHHKAJPP_01472 9.6e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHHKAJPP_01473 3.4e-10 O ADP-ribosylglycohydrolase
GHHKAJPP_01474 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
GHHKAJPP_01475 1.9e-62 ycaO O OsmC-like protein
GHHKAJPP_01477 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
GHHKAJPP_01479 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
GHHKAJPP_01480 4.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GHHKAJPP_01481 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHHKAJPP_01482 3.5e-97 3.1.3.18 S IA, variant 1
GHHKAJPP_01483 1.9e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GHHKAJPP_01484 5.9e-56 lrgA S Effector of murein hydrolase LrgA
GHHKAJPP_01486 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
GHHKAJPP_01487 1.8e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
GHHKAJPP_01488 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHHKAJPP_01489 1.6e-102 wecD M Acetyltransferase (GNAT) domain
GHHKAJPP_01490 3.3e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GHHKAJPP_01491 4.3e-92 GK ROK family
GHHKAJPP_01492 3.1e-54 GK ROK family
GHHKAJPP_01493 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
GHHKAJPP_01494 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
GHHKAJPP_01495 1.3e-204 potD P spermidine putrescine ABC transporter
GHHKAJPP_01496 2.6e-130 potC P ABC-type spermidine putrescine transport system, permease component II
GHHKAJPP_01497 1.8e-139 potB P ABC-type spermidine putrescine transport system, permease component I
GHHKAJPP_01498 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GHHKAJPP_01499 5.8e-166 murB 1.3.1.98 M cell wall formation
GHHKAJPP_01500 9.4e-78 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GHHKAJPP_01501 1.9e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GHHKAJPP_01502 2e-293 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GHHKAJPP_01503 1.2e-143 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GHHKAJPP_01504 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
GHHKAJPP_01505 0.0 ydaO E amino acid
GHHKAJPP_01506 3.4e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHHKAJPP_01507 1.5e-36 ylqC L Belongs to the UPF0109 family
GHHKAJPP_01508 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GHHKAJPP_01510 6.6e-211 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_01511 9.3e-122 agrA KT phosphorelay signal transduction system
GHHKAJPP_01512 2.3e-168 O protein import
GHHKAJPP_01514 4.8e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
GHHKAJPP_01515 2.9e-17 yjdB S Domain of unknown function (DUF4767)
GHHKAJPP_01517 3.4e-157 xth 3.1.11.2 L exodeoxyribonuclease III
GHHKAJPP_01518 5.4e-70 S QueT transporter
GHHKAJPP_01520 3.8e-171 yfjR K regulation of single-species biofilm formation
GHHKAJPP_01522 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GHHKAJPP_01523 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GHHKAJPP_01524 1.1e-84 ccl S cog cog4708
GHHKAJPP_01525 8.4e-160 rbn E Belongs to the UPF0761 family
GHHKAJPP_01526 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GHHKAJPP_01527 2.5e-231 ytoI K transcriptional regulator containing CBS domains
GHHKAJPP_01528 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
GHHKAJPP_01529 7.9e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHHKAJPP_01530 0.0 comEC S Competence protein ComEC
GHHKAJPP_01531 1.4e-90 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GHHKAJPP_01532 1.1e-141 plsC 2.3.1.51 I Acyltransferase
GHHKAJPP_01533 1.3e-147 nodB3 G Polysaccharide deacetylase
GHHKAJPP_01534 3e-139 yabB 2.1.1.223 L Methyltransferase
GHHKAJPP_01535 4.3e-40 yazA L endonuclease containing a URI domain
GHHKAJPP_01538 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GHHKAJPP_01539 1.8e-151 corA P CorA-like protein
GHHKAJPP_01540 9.6e-62 yjqA S Bacterial PH domain
GHHKAJPP_01541 1.8e-96 thiT S Thiamine transporter
GHHKAJPP_01542 2.9e-151 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
GHHKAJPP_01543 1.8e-196 yjbB G Permeases of the major facilitator superfamily
GHHKAJPP_01544 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GHHKAJPP_01545 1.8e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
GHHKAJPP_01546 3.3e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GHHKAJPP_01550 9.7e-155 cjaA ET ABC transporter substrate-binding protein
GHHKAJPP_01551 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
GHHKAJPP_01552 3e-106 P ABC transporter (Permease
GHHKAJPP_01553 1.1e-113 papP P ABC transporter (Permease
GHHKAJPP_01554 6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GHHKAJPP_01555 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
GHHKAJPP_01556 0.0 copA 3.6.3.54 P P-type ATPase
GHHKAJPP_01557 7.2e-74 copY K negative regulation of transcription, DNA-templated
GHHKAJPP_01560 2.8e-140 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GHHKAJPP_01561 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GHHKAJPP_01562 2.8e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
GHHKAJPP_01563 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GHHKAJPP_01564 3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GHHKAJPP_01565 1e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
GHHKAJPP_01566 6.3e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GHHKAJPP_01567 2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
GHHKAJPP_01568 2.2e-58
GHHKAJPP_01569 0.0 ctpE P E1-E2 ATPase
GHHKAJPP_01570 2e-46
GHHKAJPP_01571 1.1e-21 fruR K transcriptional
GHHKAJPP_01572 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GHHKAJPP_01573 5.3e-163 T Diguanylate cyclase
GHHKAJPP_01574 1.4e-19 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GHHKAJPP_01575 3.4e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GHHKAJPP_01576 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
GHHKAJPP_01577 0.0
GHHKAJPP_01578 5.1e-27 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHHKAJPP_01579 1.2e-74
GHHKAJPP_01580 7.6e-110 K Peptidase S24-like protein
GHHKAJPP_01581 8.9e-107 E IrrE N-terminal-like domain
GHHKAJPP_01582 9.9e-93
GHHKAJPP_01583 6.9e-79
GHHKAJPP_01584 3.5e-43
GHHKAJPP_01585 2.9e-50
GHHKAJPP_01586 2e-43
GHHKAJPP_01587 8.7e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GHHKAJPP_01589 1.9e-124 V abc transporter atp-binding protein
GHHKAJPP_01590 0.0 V ABC transporter (Permease
GHHKAJPP_01591 5.2e-125 K transcriptional regulator, MerR family
GHHKAJPP_01592 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
GHHKAJPP_01593 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
GHHKAJPP_01594 9.6e-64 XK27_02560 S cog cog2151
GHHKAJPP_01595 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GHHKAJPP_01596 6.3e-221 ytfP S Flavoprotein
GHHKAJPP_01598 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GHHKAJPP_01599 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
GHHKAJPP_01600 6e-175 ecsB U Bacterial ABC transporter protein EcsB
GHHKAJPP_01601 8.4e-131 ecsA V abc transporter atp-binding protein
GHHKAJPP_01602 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GHHKAJPP_01603 4.2e-12
GHHKAJPP_01606 1.6e-103
GHHKAJPP_01608 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
GHHKAJPP_01609 6.7e-43 yoeB S Addiction module toxin, Txe YoeB family
GHHKAJPP_01610 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GHHKAJPP_01611 4.5e-197 ylbM S Belongs to the UPF0348 family
GHHKAJPP_01612 2.2e-139 yqeM Q Methyltransferase domain protein
GHHKAJPP_01613 1e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GHHKAJPP_01614 1.1e-86 entB 3.5.1.19 Q Isochorismatase family
GHHKAJPP_01615 3.7e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GHHKAJPP_01616 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GHHKAJPP_01617 7.7e-49 yhbY J RNA-binding protein
GHHKAJPP_01618 9.2e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GHHKAJPP_01619 1e-98 yqeG S hydrolase of the HAD superfamily
GHHKAJPP_01620 1e-149 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GHHKAJPP_01621 1.5e-62
GHHKAJPP_01623 1.1e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHHKAJPP_01624 4.2e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GHHKAJPP_01625 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHHKAJPP_01626 1.2e-232 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GHHKAJPP_01627 4e-192 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GHHKAJPP_01628 1.8e-156 H COG0463 Glycosyltransferases involved in cell wall biogenesis
GHHKAJPP_01629 8.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
GHHKAJPP_01630 1.1e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHHKAJPP_01631 6.4e-99 pncA Q isochorismatase
GHHKAJPP_01632 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GHHKAJPP_01633 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
GHHKAJPP_01634 9e-75 XK27_03180 T universal stress protein
GHHKAJPP_01636 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHHKAJPP_01637 1.4e-08 MU outer membrane autotransporter barrel domain protein
GHHKAJPP_01638 5.4e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
GHHKAJPP_01639 7.3e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
GHHKAJPP_01641 2.7e-25
GHHKAJPP_01642 0.0 yjcE P NhaP-type Na H and K H antiporters
GHHKAJPP_01644 1e-93 ytqB 2.1.1.176 J (SAM)-dependent
GHHKAJPP_01645 7.9e-182 yhcC S radical SAM protein
GHHKAJPP_01646 6.4e-188 ylbL T Belongs to the peptidase S16 family
GHHKAJPP_01647 3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GHHKAJPP_01648 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
GHHKAJPP_01649 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHHKAJPP_01650 5e-10 S Protein of unknown function (DUF4059)
GHHKAJPP_01651 1.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
GHHKAJPP_01652 1.8e-162 yxeN P ABC transporter (Permease
GHHKAJPP_01653 1.5e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GHHKAJPP_01654 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GHHKAJPP_01655 3.6e-35
GHHKAJPP_01656 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHHKAJPP_01657 0.0 pflB 2.3.1.54 C formate acetyltransferase'
GHHKAJPP_01658 3.3e-141 cah 4.2.1.1 P carbonic anhydrase
GHHKAJPP_01659 5.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GHHKAJPP_01661 1.3e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
GHHKAJPP_01662 3.1e-136 cppA E CppA N-terminal
GHHKAJPP_01663 1.8e-95 V CAAX protease self-immunity
GHHKAJPP_01664 4.7e-149 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GHHKAJPP_01665 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GHHKAJPP_01666 3.1e-44 spiA K sequence-specific DNA binding
GHHKAJPP_01675 0.0 mdlB V abc transporter atp-binding protein
GHHKAJPP_01676 0.0 mdlA V abc transporter atp-binding protein
GHHKAJPP_01679 1.3e-88 XK27_09885 V Glycopeptide antibiotics resistance protein
GHHKAJPP_01680 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GHHKAJPP_01681 5.7e-63 yutD J protein conserved in bacteria
GHHKAJPP_01682 5e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GHHKAJPP_01684 9.8e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GHHKAJPP_01685 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHHKAJPP_01686 0.0 ftsI 3.4.16.4 M penicillin-binding protein
GHHKAJPP_01687 4e-45 ftsL D cell division protein FtsL
GHHKAJPP_01688 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GHHKAJPP_01689 4.2e-96
GHHKAJPP_01691 2.7e-37 yhaI J Protein of unknown function (DUF805)
GHHKAJPP_01692 1.6e-64 yhaI J Protein of unknown function (DUF805)
GHHKAJPP_01693 6.6e-58 yhaI J Membrane
GHHKAJPP_01694 4.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GHHKAJPP_01695 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GHHKAJPP_01696 2.3e-266 XK27_00765
GHHKAJPP_01697 1.5e-132 ecsA_2 V abc transporter atp-binding protein
GHHKAJPP_01698 3.6e-126 S Protein of unknown function (DUF554)
GHHKAJPP_01699 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHHKAJPP_01700 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GHHKAJPP_01701 3.7e-233 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_01702 2.7e-225 dcuS 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_01703 1.5e-13
GHHKAJPP_01706 5.8e-146 V Psort location CytoplasmicMembrane, score
GHHKAJPP_01708 3e-298 O MreB/Mbl protein
GHHKAJPP_01709 2.6e-194 mccF V LD-carboxypeptidase
GHHKAJPP_01710 4e-43 S Sugar efflux transporter for intercellular exchange
GHHKAJPP_01711 5.6e-77 mccF V LD-carboxypeptidase
GHHKAJPP_01712 8.2e-120 liaI S membrane
GHHKAJPP_01713 1.3e-73 XK27_02470 K LytTr DNA-binding domain
GHHKAJPP_01714 1.5e-308 KT response to antibiotic
GHHKAJPP_01715 2.9e-117 yebC M Membrane
GHHKAJPP_01716 5.4e-256 XK27_03190 S hydrolases of the HAD superfamily
GHHKAJPP_01717 2.3e-176 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GHHKAJPP_01719 2.9e-31 yozG K Transcriptional regulator
GHHKAJPP_01723 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHHKAJPP_01724 1.6e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHHKAJPP_01725 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GHHKAJPP_01726 1e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHHKAJPP_01727 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHHKAJPP_01728 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHHKAJPP_01730 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
GHHKAJPP_01731 7.2e-169 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
GHHKAJPP_01732 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_01733 2.7e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GHHKAJPP_01734 1.1e-178 scrR K Transcriptional regulator
GHHKAJPP_01735 3.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GHHKAJPP_01736 1.7e-61 yqhY S protein conserved in bacteria
GHHKAJPP_01737 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHHKAJPP_01738 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
GHHKAJPP_01739 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
GHHKAJPP_01741 1.8e-145 V 'abc transporter, ATP-binding protein
GHHKAJPP_01748 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GHHKAJPP_01749 1.2e-166 corA P COG0598 Mg2 and Co2 transporters
GHHKAJPP_01750 7.2e-121 XK27_01040 S Protein of unknown function (DUF1129)
GHHKAJPP_01752 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHHKAJPP_01753 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GHHKAJPP_01754 1.1e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
GHHKAJPP_01755 5.5e-42 XK27_05745
GHHKAJPP_01756 1.1e-222 mutY L A G-specific adenine glycosylase
GHHKAJPP_01758 2.9e-09
GHHKAJPP_01759 1.6e-38
GHHKAJPP_01761 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHHKAJPP_01762 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GHHKAJPP_01763 1.2e-89 cvpA S toxin biosynthetic process
GHHKAJPP_01764 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GHHKAJPP_01765 2.9e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHHKAJPP_01766 7.4e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHHKAJPP_01767 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GHHKAJPP_01768 1.3e-46 azlD S branched-chain amino acid
GHHKAJPP_01769 2.6e-113 azlC E AzlC protein
GHHKAJPP_01770 6.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GHHKAJPP_01771 1.5e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GHHKAJPP_01772 1.5e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
GHHKAJPP_01773 3.3e-33 ykzG S Belongs to the UPF0356 family
GHHKAJPP_01774 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHHKAJPP_01775 2.8e-114 pscB M CHAP domain protein
GHHKAJPP_01776 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
GHHKAJPP_01777 8.5e-63 glnR K Transcriptional regulator
GHHKAJPP_01778 2.5e-86 S Fusaric acid resistance protein-like
GHHKAJPP_01779 9.9e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GHHKAJPP_01780 5.7e-102
GHHKAJPP_01781 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
GHHKAJPP_01782 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GHHKAJPP_01783 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GHHKAJPP_01784 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GHHKAJPP_01785 4e-142 purR 2.4.2.7 F operon repressor
GHHKAJPP_01786 1.7e-176 cbf S 3'-5' exoribonuclease yhaM
GHHKAJPP_01787 7.9e-169 rmuC S RmuC domain protein
GHHKAJPP_01788 4e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
GHHKAJPP_01789 1e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GHHKAJPP_01790 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GHHKAJPP_01792 3.5e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GHHKAJPP_01793 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GHHKAJPP_01794 1e-142 tatD L Hydrolase, tatd
GHHKAJPP_01795 1.7e-70 yccU S CoA-binding protein
GHHKAJPP_01796 5.3e-50 trxA O Belongs to the thioredoxin family
GHHKAJPP_01797 5.6e-141 S Macro domain protein
GHHKAJPP_01798 6.3e-59 L thioesterase
GHHKAJPP_01799 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
GHHKAJPP_01802 9.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GHHKAJPP_01803 3.4e-14 rpmH J Ribosomal protein L34
GHHKAJPP_01804 1.7e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GHHKAJPP_01805 4.5e-98 K Transcriptional regulator
GHHKAJPP_01806 1.1e-168 jag S RNA-binding protein
GHHKAJPP_01807 1.1e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHHKAJPP_01808 3.5e-52 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GHHKAJPP_01809 1.7e-262 argH 4.3.2.1 E Argininosuccinate lyase
GHHKAJPP_01810 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GHHKAJPP_01811 2.7e-129 fasA KT Response regulator of the LytR AlgR family
GHHKAJPP_01812 2.8e-225 fasC T protein histidine kinase activity
GHHKAJPP_01813 9.3e-210 hpk9 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_01814 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
GHHKAJPP_01815 1.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GHHKAJPP_01816 3e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GHHKAJPP_01817 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GHHKAJPP_01818 2.6e-118 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GHHKAJPP_01819 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GHHKAJPP_01820 1.2e-50 S Protein of unknown function (DUF3397)
GHHKAJPP_01821 3.3e-86 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GHHKAJPP_01822 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
GHHKAJPP_01823 6.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHHKAJPP_01824 1e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GHHKAJPP_01825 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GHHKAJPP_01826 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
GHHKAJPP_01827 7.9e-230 XK27_09615 C reductase
GHHKAJPP_01828 9.6e-141 fnt P Formate nitrite transporter
GHHKAJPP_01829 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
GHHKAJPP_01830 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GHHKAJPP_01831 4.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GHHKAJPP_01832 4.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GHHKAJPP_01833 2.9e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GHHKAJPP_01834 1.1e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GHHKAJPP_01835 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GHHKAJPP_01836 7.5e-127 S HAD hydrolase, family IA, variant
GHHKAJPP_01837 1.7e-156 rrmA 2.1.1.187 Q methyltransferase
GHHKAJPP_01841 7.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GHHKAJPP_01842 2.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GHHKAJPP_01843 8.9e-119 S CAAX protease self-immunity
GHHKAJPP_01844 3.7e-111 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHHKAJPP_01845 7.6e-09 S NTF2 fold immunity protein
GHHKAJPP_01846 9.4e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GHHKAJPP_01847 1.6e-08 XK27_10305 S Domain of unknown function (DUF4651)
GHHKAJPP_01848 2.7e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GHHKAJPP_01849 3.5e-127 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GHHKAJPP_01850 1.6e-101 S CAAX amino terminal protease family protein
GHHKAJPP_01852 3.5e-104 V CAAX protease self-immunity
GHHKAJPP_01853 4.4e-26 lanR K sequence-specific DNA binding
GHHKAJPP_01854 2.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHHKAJPP_01855 6.5e-176 ytxK 2.1.1.72 L DNA methylase
GHHKAJPP_01856 5.2e-13 comGF U Putative Competence protein ComGF
GHHKAJPP_01857 1.3e-70 comGF U Competence protein ComGF
GHHKAJPP_01858 6.3e-16 NU Type II secretory pathway pseudopilin
GHHKAJPP_01859 7.1e-69 cglD NU Competence protein
GHHKAJPP_01860 2.2e-43 comGC U Required for transformation and DNA binding
GHHKAJPP_01861 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GHHKAJPP_01862 7.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GHHKAJPP_01863 1e-68 S cog cog4699
GHHKAJPP_01864 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHHKAJPP_01865 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHHKAJPP_01866 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GHHKAJPP_01867 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GHHKAJPP_01868 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GHHKAJPP_01869 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
GHHKAJPP_01870 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
GHHKAJPP_01871 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GHHKAJPP_01872 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
GHHKAJPP_01873 1.4e-57 asp S cog cog1302
GHHKAJPP_01874 9.6e-223 norN V Mate efflux family protein
GHHKAJPP_01875 1.9e-275 thrC 4.2.3.1 E Threonine synthase
GHHKAJPP_01878 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GHHKAJPP_01879 0.0 pepO 3.4.24.71 O Peptidase family M13
GHHKAJPP_01880 1.5e-258 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GHHKAJPP_01881 5.7e-95 ywlG S Belongs to the UPF0340 family
GHHKAJPP_01884 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
GHHKAJPP_01886 2.6e-244 6.3.2.2 H gamma-glutamylcysteine synthetase
GHHKAJPP_01887 4.4e-62 rplQ J ribosomal protein l17
GHHKAJPP_01888 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHHKAJPP_01889 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GHHKAJPP_01890 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GHHKAJPP_01891 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GHHKAJPP_01892 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GHHKAJPP_01893 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHHKAJPP_01894 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GHHKAJPP_01895 5.7e-58 rplO J binds to the 23S rRNA
GHHKAJPP_01896 1.9e-23 rpmD J ribosomal protein l30
GHHKAJPP_01897 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GHHKAJPP_01898 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GHHKAJPP_01899 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GHHKAJPP_01900 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GHHKAJPP_01901 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHHKAJPP_01902 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GHHKAJPP_01903 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GHHKAJPP_01904 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GHHKAJPP_01905 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GHHKAJPP_01906 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
GHHKAJPP_01907 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GHHKAJPP_01908 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GHHKAJPP_01909 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GHHKAJPP_01910 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GHHKAJPP_01911 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GHHKAJPP_01912 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GHHKAJPP_01913 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
GHHKAJPP_01914 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GHHKAJPP_01915 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GHHKAJPP_01916 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GHHKAJPP_01917 0.0 XK27_09800 I Acyltransferase
GHHKAJPP_01918 2.8e-35 XK27_09805 S MORN repeat protein
GHHKAJPP_01919 1.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHHKAJPP_01920 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GHHKAJPP_01921 2.9e-90 adk 2.7.4.3 F topology modulation protein
GHHKAJPP_01923 4.9e-174 yeiH S membrane
GHHKAJPP_01924 5.5e-89 K sequence-specific DNA binding
GHHKAJPP_01925 1.2e-156 L Replication initiation factor
GHHKAJPP_01926 1.9e-18 S Domain of unknown function (DUF3173)
GHHKAJPP_01927 1.5e-214 int L Belongs to the 'phage' integrase family
GHHKAJPP_01929 8.2e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
GHHKAJPP_01930 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GHHKAJPP_01931 6.3e-44 yrzL S Belongs to the UPF0297 family
GHHKAJPP_01932 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GHHKAJPP_01933 3.2e-44 yrzB S Belongs to the UPF0473 family
GHHKAJPP_01934 1.3e-288 ccs S the current gene model (or a revised gene model) may contain a frame shift
GHHKAJPP_01935 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GHHKAJPP_01936 7.5e-14
GHHKAJPP_01937 7.3e-86 XK27_10930 K acetyltransferase
GHHKAJPP_01938 1.5e-114 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHHKAJPP_01939 6.9e-119 yaaA S Belongs to the UPF0246 family
GHHKAJPP_01940 9.3e-167 XK27_01785 S cog cog1284
GHHKAJPP_01941 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GHHKAJPP_01943 8e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
GHHKAJPP_01944 3.9e-73 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_01945 5.8e-50 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_01946 8e-08 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GHHKAJPP_01947 1.2e-218 metE 2.1.1.14 E Methionine synthase
GHHKAJPP_01948 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GHHKAJPP_01949 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GHHKAJPP_01950 3.3e-28
GHHKAJPP_01953 7.4e-80
GHHKAJPP_01954 2.9e-46 K DNA-binding protein
GHHKAJPP_01958 2.7e-121 D ftsk spoiiie
GHHKAJPP_01959 2.1e-206 S Replication initiation factor
GHHKAJPP_01960 2.8e-28 S MerR HTH family regulatory protein
GHHKAJPP_01961 6.8e-221 sip L Belongs to the 'phage' integrase family
GHHKAJPP_01962 4.3e-132
GHHKAJPP_01964 1.6e-72 S EcsC protein family
GHHKAJPP_01966 1.8e-47
GHHKAJPP_01967 4e-140
GHHKAJPP_01968 1.4e-284 dcm 2.1.1.37, 2.1.1.72 H Adenine-specific methyltransferase EcoRI
GHHKAJPP_01969 2.7e-107 K Peptidase S24-like protein
GHHKAJPP_01970 4e-108 E IrrE N-terminal-like domain
GHHKAJPP_01972 1.1e-48 K Helix-turn-helix XRE-family like proteins
GHHKAJPP_01973 1.7e-42
GHHKAJPP_01974 7.2e-72
GHHKAJPP_01975 7e-274 ydcQ D Ftsk spoiiie family protein
GHHKAJPP_01976 1.3e-221 K Replication initiation factor
GHHKAJPP_01977 4.3e-33
GHHKAJPP_01978 2.3e-88
GHHKAJPP_01979 1.2e-161 S Conjugative transposon protein TcpC
GHHKAJPP_01980 3.2e-33
GHHKAJPP_01981 2.7e-70 S TcpE family
GHHKAJPP_01982 0.0 yddE S AAA-like domain
GHHKAJPP_01983 6.2e-263
GHHKAJPP_01984 2e-30
GHHKAJPP_01985 1.4e-169 isp2 S pathogenesis
GHHKAJPP_01986 6.1e-36 S MerR HTH family regulatory protein
GHHKAJPP_01987 2.7e-217 sip L Phage integrase, N-terminal SAM-like domain
GHHKAJPP_01988 3.7e-12
GHHKAJPP_01990 1.1e-16 U Preprotein translocase subunit SecB
GHHKAJPP_01991 3.3e-07
GHHKAJPP_01994 3.8e-113 nudL L hydrolase
GHHKAJPP_01995 5e-51 K transcriptional regulator, PadR family
GHHKAJPP_01996 4e-59 XK27_06920 S Protein of unknown function (DUF1700)
GHHKAJPP_01997 1.6e-101 S Putative adhesin
GHHKAJPP_01998 3.9e-161 XK27_06930 V domain protein
GHHKAJPP_01999 1.3e-93 XK27_06935 K transcriptional regulator
GHHKAJPP_02000 2.2e-52 ypaA M Membrane
GHHKAJPP_02001 1.1e-10
GHHKAJPP_02002 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GHHKAJPP_02003 1.8e-47 veg S Biofilm formation stimulator VEG
GHHKAJPP_02004 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GHHKAJPP_02005 2.2e-73 rplI J binds to the 23S rRNA
GHHKAJPP_02006 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GHHKAJPP_02007 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GHHKAJPP_02008 2.5e-96 yvbG U UPF0056 membrane protein
GHHKAJPP_02009 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GHHKAJPP_02010 8.6e-304 S Bacterial membrane protein, YfhO
GHHKAJPP_02011 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
GHHKAJPP_02012 1.6e-60 lytE M LysM domain protein
GHHKAJPP_02013 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHHKAJPP_02014 1.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHHKAJPP_02015 7.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHHKAJPP_02016 5.9e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHHKAJPP_02017 5.4e-129 S sequence-specific DNA binding
GHHKAJPP_02018 2e-233 ymfH S Peptidase M16
GHHKAJPP_02019 5.6e-228 ymfF S Peptidase M16
GHHKAJPP_02020 6.4e-58 yaaA S S4 domain protein YaaA
GHHKAJPP_02021 1.2e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GHHKAJPP_02022 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GHHKAJPP_02023 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GHHKAJPP_02024 9.3e-153 yvjA S membrane
GHHKAJPP_02025 1.1e-305 ybiT S abc transporter atp-binding protein
GHHKAJPP_02026 0.0 XK27_10405 S Bacterial membrane protein YfhO
GHHKAJPP_02030 2.2e-117 yoaK S Protein of unknown function (DUF1275)
GHHKAJPP_02031 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHHKAJPP_02032 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GHHKAJPP_02033 3.2e-133 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)