ORF_ID e_value Gene_name EC_number CAZy COGs Description
PGNNCGIA_00001 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGNNCGIA_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGNNCGIA_00003 1.1e-29 yyzM S Protein conserved in bacteria
PGNNCGIA_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGNNCGIA_00005 6.8e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGNNCGIA_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGNNCGIA_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PGNNCGIA_00008 3e-60 divIC D Septum formation initiator
PGNNCGIA_00010 1.3e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PGNNCGIA_00011 2.4e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGNNCGIA_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PGNNCGIA_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGNNCGIA_00023 2.6e-10
PGNNCGIA_00029 3.2e-110 mreC M Involved in formation and maintenance of cell shape
PGNNCGIA_00030 3e-82 mreD M rod shape-determining protein MreD
PGNNCGIA_00031 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
PGNNCGIA_00032 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGNNCGIA_00033 1.1e-217 araT 2.6.1.1 E Aminotransferase
PGNNCGIA_00034 8e-140 recO L Involved in DNA repair and RecF pathway recombination
PGNNCGIA_00035 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGNNCGIA_00036 1.2e-28 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGNNCGIA_00037 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PGNNCGIA_00038 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGNNCGIA_00039 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGNNCGIA_00040 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PGNNCGIA_00041 1.2e-97 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGNNCGIA_00042 8.6e-30
PGNNCGIA_00043 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PGNNCGIA_00046 5e-157 2.7.7.49 L reverse transcriptase
PGNNCGIA_00047 2e-157 S CHAP domain
PGNNCGIA_00049 2.5e-239 purD 6.3.4.13 F Belongs to the GARS family
PGNNCGIA_00050 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGNNCGIA_00051 8.7e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGNNCGIA_00052 4.7e-174 1.1.1.169 H Ketopantoate reductase
PGNNCGIA_00053 1.9e-33
PGNNCGIA_00054 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGNNCGIA_00055 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PGNNCGIA_00056 6.9e-69 argR K Regulates arginine biosynthesis genes
PGNNCGIA_00057 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PGNNCGIA_00058 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGNNCGIA_00059 1.5e-77 S Protein of unknown function (DUF3021)
PGNNCGIA_00060 1.1e-69 K LytTr DNA-binding domain
PGNNCGIA_00062 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGNNCGIA_00064 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGNNCGIA_00065 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PGNNCGIA_00066 8.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
PGNNCGIA_00067 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGNNCGIA_00068 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PGNNCGIA_00076 2.6e-10
PGNNCGIA_00079 1.9e-07
PGNNCGIA_00084 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGNNCGIA_00085 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PGNNCGIA_00086 1.2e-35 XK27_02060 S Transglycosylase associated protein
PGNNCGIA_00087 2.2e-70 badR K Transcriptional regulator, marr family
PGNNCGIA_00088 2.3e-93 S reductase
PGNNCGIA_00090 4.5e-288 ahpF O alkyl hydroperoxide reductase
PGNNCGIA_00091 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
PGNNCGIA_00092 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
PGNNCGIA_00093 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGNNCGIA_00094 1.6e-82 S Putative small multi-drug export protein
PGNNCGIA_00095 1.8e-75 ctsR K Belongs to the CtsR family
PGNNCGIA_00096 0.0 clpC O Belongs to the ClpA ClpB family
PGNNCGIA_00097 1e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGNNCGIA_00098 1.4e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGNNCGIA_00099 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PGNNCGIA_00100 1e-139 S SseB protein N-terminal domain
PGNNCGIA_00101 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
PGNNCGIA_00103 6.9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGNNCGIA_00104 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGNNCGIA_00106 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGNNCGIA_00107 6e-91 yacP S RNA-binding protein containing a PIN domain
PGNNCGIA_00108 5.9e-152 degV S DegV family
PGNNCGIA_00110 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGNNCGIA_00111 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PGNNCGIA_00112 2.5e-104 yiiE S protein homotetramerization
PGNNCGIA_00113 4.9e-81 copY K Copper transport repressor, CopY TcrY family
PGNNCGIA_00114 0.0 3.6.3.4 P P-type ATPase
PGNNCGIA_00116 1.2e-101 cadD P cadmium resistance
PGNNCGIA_00117 4.5e-55 cadC K Bacterial regulatory protein, arsR family
PGNNCGIA_00118 1.8e-19
PGNNCGIA_00119 4.5e-29 K Helix-turn-helix domain
PGNNCGIA_00121 2e-149 srtB 3.4.22.70 S Sortase family
PGNNCGIA_00122 4.3e-233 capA M Bacterial capsule synthesis protein
PGNNCGIA_00123 1e-38 gcvR T UPF0237 protein
PGNNCGIA_00124 8.7e-243 XK27_08635 S UPF0210 protein
PGNNCGIA_00125 9.5e-132 ais G Phosphoglycerate mutase
PGNNCGIA_00126 4.8e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PGNNCGIA_00127 1.7e-97 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
PGNNCGIA_00128 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGNNCGIA_00129 5.7e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGNNCGIA_00130 6e-303 dnaK O Heat shock 70 kDa protein
PGNNCGIA_00131 1.1e-105 thiJ-2 3.5.1.124 S DJ-1/PfpI family
PGNNCGIA_00132 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGNNCGIA_00133 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGNNCGIA_00134 4.9e-134 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PGNNCGIA_00135 1.1e-78 hmpT S cog cog4720
PGNNCGIA_00149 1.9e-86 sigH K DNA-templated transcription, initiation
PGNNCGIA_00150 5.8e-138 ykuT M mechanosensitive ion channel
PGNNCGIA_00151 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGNNCGIA_00152 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGNNCGIA_00153 2.4e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGNNCGIA_00154 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
PGNNCGIA_00155 2.1e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PGNNCGIA_00156 1e-176 prmA J Ribosomal protein L11 methyltransferase
PGNNCGIA_00157 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGNNCGIA_00158 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PGNNCGIA_00159 5.9e-82 nrdI F Belongs to the NrdI family
PGNNCGIA_00160 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGNNCGIA_00161 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGNNCGIA_00162 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PGNNCGIA_00163 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGNNCGIA_00164 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGNNCGIA_00165 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PGNNCGIA_00166 7.6e-195 yhjX P Major Facilitator
PGNNCGIA_00167 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGNNCGIA_00168 1.8e-83 V VanZ like family
PGNNCGIA_00169 2.1e-181 D nuclear chromosome segregation
PGNNCGIA_00170 2.9e-123 glnQ E abc transporter atp-binding protein
PGNNCGIA_00171 1.3e-271 glnP P ABC transporter
PGNNCGIA_00172 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGNNCGIA_00173 4.8e-18 S Protein of unknown function (DUF3021)
PGNNCGIA_00174 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PGNNCGIA_00175 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
PGNNCGIA_00176 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PGNNCGIA_00177 1.2e-233 sufD O assembly protein SufD
PGNNCGIA_00178 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGNNCGIA_00179 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
PGNNCGIA_00180 2.9e-273 sufB O assembly protein SufB
PGNNCGIA_00181 3.6e-26
PGNNCGIA_00182 1e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGNNCGIA_00183 6.2e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGNNCGIA_00184 1.6e-71 adcR K transcriptional
PGNNCGIA_00185 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
PGNNCGIA_00186 5.1e-129 adcB P ABC transporter (Permease
PGNNCGIA_00187 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PGNNCGIA_00188 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PGNNCGIA_00189 1.2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PGNNCGIA_00190 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
PGNNCGIA_00191 2.2e-146 Z012_04635 K sequence-specific DNA binding
PGNNCGIA_00192 3.8e-282 V ABC transporter
PGNNCGIA_00193 6.1e-126 yeeN K transcriptional regulatory protein
PGNNCGIA_00194 4.5e-47 yajC U protein transport
PGNNCGIA_00195 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGNNCGIA_00196 5.5e-144 cdsA 2.7.7.41 S Belongs to the CDS family
PGNNCGIA_00197 5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PGNNCGIA_00198 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGNNCGIA_00199 0.0 WQ51_06230 S ABC transporter
PGNNCGIA_00200 2.6e-141 cmpC S abc transporter atp-binding protein
PGNNCGIA_00201 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGNNCGIA_00202 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGNNCGIA_00204 5.5e-44
PGNNCGIA_00205 1.7e-54 S TM2 domain
PGNNCGIA_00206 2.6e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGNNCGIA_00207 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGNNCGIA_00208 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGNNCGIA_00209 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
PGNNCGIA_00210 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PGNNCGIA_00211 4.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PGNNCGIA_00212 5.6e-144 cof S Sucrose-6F-phosphate phosphohydrolase
PGNNCGIA_00213 6.5e-134 glcR K transcriptional regulator (DeoR family)
PGNNCGIA_00214 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGNNCGIA_00215 5.5e-72 K helix_turn_helix multiple antibiotic resistance protein
PGNNCGIA_00216 2.8e-224 S COG1073 Hydrolases of the alpha beta superfamily
PGNNCGIA_00217 7.5e-36 yjdF S Protein of unknown function (DUF2992)
PGNNCGIA_00218 2.2e-45 3.2.2.21 S YCII-related domain
PGNNCGIA_00219 1.5e-52 K regulation of RNA biosynthetic process
PGNNCGIA_00220 2.4e-153 cylA V abc transporter atp-binding protein
PGNNCGIA_00221 4.6e-133 cylB V ABC-2 type transporter
PGNNCGIA_00222 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
PGNNCGIA_00223 2.3e-32 S Protein of unknown function (DUF3021)
PGNNCGIA_00224 1.3e-123 mta K Transcriptional
PGNNCGIA_00225 2.5e-121 yhcA V abc transporter atp-binding protein
PGNNCGIA_00226 6.7e-216 macB_2 V FtsX-like permease family
PGNNCGIA_00227 8.4e-276 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGNNCGIA_00228 9e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGNNCGIA_00229 1.3e-73 yhaI S Protein of unknown function (DUF805)
PGNNCGIA_00230 1.7e-254 pepC 3.4.22.40 E aminopeptidase
PGNNCGIA_00231 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGNNCGIA_00232 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGNNCGIA_00233 2.6e-94 ypsA S Belongs to the UPF0398 family
PGNNCGIA_00234 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGNNCGIA_00235 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PGNNCGIA_00236 2.8e-282 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PGNNCGIA_00237 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PGNNCGIA_00238 9.6e-23
PGNNCGIA_00239 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PGNNCGIA_00240 1.2e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
PGNNCGIA_00241 4.8e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGNNCGIA_00242 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGNNCGIA_00243 1.7e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGNNCGIA_00244 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PGNNCGIA_00245 7.9e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGNNCGIA_00246 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PGNNCGIA_00247 2.2e-101 ybhL S Belongs to the BI1 family
PGNNCGIA_00248 5.5e-12 ycdA S Domain of unknown function (DUF4352)
PGNNCGIA_00249 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGNNCGIA_00250 1.8e-90 K transcriptional regulator
PGNNCGIA_00251 1.6e-36 yneF S UPF0154 protein
PGNNCGIA_00252 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PGNNCGIA_00253 6.6e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGNNCGIA_00254 3.9e-98 XK27_09740 S Phosphoesterase
PGNNCGIA_00255 8.3e-87 ykuL S CBS domain
PGNNCGIA_00256 2.5e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PGNNCGIA_00257 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGNNCGIA_00258 1.2e-92 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGNNCGIA_00259 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGNNCGIA_00260 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PGNNCGIA_00261 1.8e-257 trkH P Cation transport protein
PGNNCGIA_00262 9.3e-245 trkA P Potassium transporter peripheral membrane component
PGNNCGIA_00263 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGNNCGIA_00264 9.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGNNCGIA_00265 2.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PGNNCGIA_00266 5.6e-153 K sequence-specific DNA binding
PGNNCGIA_00267 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PGNNCGIA_00268 1.3e-54 yhaI L Membrane
PGNNCGIA_00269 1.9e-245 S Domain of unknown function (DUF4173)
PGNNCGIA_00270 6.8e-95 ureI S AmiS/UreI family transporter
PGNNCGIA_00271 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PGNNCGIA_00272 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PGNNCGIA_00273 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PGNNCGIA_00274 6.6e-78 ureE O enzyme active site formation
PGNNCGIA_00275 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PGNNCGIA_00276 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PGNNCGIA_00277 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PGNNCGIA_00278 3.9e-176 cbiM P biosynthesis protein CbiM
PGNNCGIA_00279 1.1e-136 P cobalt transport protein
PGNNCGIA_00280 6.3e-131 cbiO P ABC transporter
PGNNCGIA_00281 3.2e-142 ET amino acid transport
PGNNCGIA_00282 1.7e-162 metQ M Belongs to the NlpA lipoprotein family
PGNNCGIA_00283 8.6e-262 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PGNNCGIA_00284 1.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGNNCGIA_00285 1.2e-99 metI P ABC transporter (Permease
PGNNCGIA_00286 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PGNNCGIA_00287 1.4e-119 ktrA P COG0569 K transport systems, NAD-binding component
PGNNCGIA_00288 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
PGNNCGIA_00289 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PGNNCGIA_00290 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
PGNNCGIA_00291 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGNNCGIA_00292 1.3e-279 T PhoQ Sensor
PGNNCGIA_00293 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGNNCGIA_00294 8.8e-215 dnaB L Replication initiation and membrane attachment
PGNNCGIA_00295 2.9e-165 dnaI L Primosomal protein DnaI
PGNNCGIA_00296 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PGNNCGIA_00297 2.8e-111
PGNNCGIA_00298 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGNNCGIA_00299 2.5e-62 manO S protein conserved in bacteria
PGNNCGIA_00300 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
PGNNCGIA_00301 4.5e-117 manM G pts system
PGNNCGIA_00302 4.9e-174 manL 2.7.1.191 G pts system
PGNNCGIA_00303 7.7e-67 manO S Protein conserved in bacteria
PGNNCGIA_00304 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
PGNNCGIA_00305 4.7e-135 manY G pts system
PGNNCGIA_00306 6.2e-169 manL 2.7.1.191 G pts system
PGNNCGIA_00307 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PGNNCGIA_00308 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PGNNCGIA_00309 1.6e-247 pbuO S permease
PGNNCGIA_00310 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PGNNCGIA_00311 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
PGNNCGIA_00312 9.8e-188 brpA K Transcriptional
PGNNCGIA_00313 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
PGNNCGIA_00314 4e-199 nusA K Participates in both transcription termination and antitermination
PGNNCGIA_00315 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PGNNCGIA_00316 1.4e-41 ylxQ J ribosomal protein
PGNNCGIA_00317 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGNNCGIA_00318 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGNNCGIA_00319 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
PGNNCGIA_00320 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PGNNCGIA_00321 8.1e-271 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGNNCGIA_00322 1.3e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PGNNCGIA_00323 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PGNNCGIA_00324 4.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
PGNNCGIA_00325 1.1e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PGNNCGIA_00326 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PGNNCGIA_00327 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PGNNCGIA_00328 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGNNCGIA_00329 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGNNCGIA_00330 1.4e-72 ylbF S Belongs to the UPF0342 family
PGNNCGIA_00331 1.9e-46 ylbG S UPF0298 protein
PGNNCGIA_00332 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PGNNCGIA_00333 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
PGNNCGIA_00334 6.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
PGNNCGIA_00335 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PGNNCGIA_00336 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PGNNCGIA_00337 7.8e-112 acuB S CBS domain
PGNNCGIA_00338 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGNNCGIA_00339 1.7e-108 yvyE 3.4.13.9 S YigZ family
PGNNCGIA_00340 1.2e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PGNNCGIA_00341 2.6e-83 comFC K competence protein
PGNNCGIA_00342 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGNNCGIA_00351 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
PGNNCGIA_00352 1.4e-102 S Domain of unknown function (DUF1803)
PGNNCGIA_00353 7.8e-102 ygaC J Belongs to the UPF0374 family
PGNNCGIA_00354 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
PGNNCGIA_00355 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGNNCGIA_00356 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
PGNNCGIA_00357 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
PGNNCGIA_00358 3.5e-117 S HAD hydrolase, family IA, variant 3
PGNNCGIA_00359 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PGNNCGIA_00360 5.2e-72 marR K Transcriptional regulator, MarR family
PGNNCGIA_00361 1.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGNNCGIA_00362 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGNNCGIA_00363 1.7e-171 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PGNNCGIA_00364 1.4e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PGNNCGIA_00365 6.2e-126 IQ reductase
PGNNCGIA_00366 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGNNCGIA_00367 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGNNCGIA_00368 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGNNCGIA_00369 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PGNNCGIA_00370 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGNNCGIA_00371 3.9e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PGNNCGIA_00372 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGNNCGIA_00373 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
PGNNCGIA_00374 5.9e-124 fruR K transcriptional
PGNNCGIA_00375 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PGNNCGIA_00376 0.0 fruA 2.7.1.202 G phosphotransferase system
PGNNCGIA_00377 5.1e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGNNCGIA_00378 2.3e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGNNCGIA_00380 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PGNNCGIA_00381 7.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGNNCGIA_00382 1.3e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGNNCGIA_00383 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGNNCGIA_00384 9.6e-84 2.3.1.128 K acetyltransferase
PGNNCGIA_00385 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PGNNCGIA_00386 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PGNNCGIA_00387 4.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGNNCGIA_00388 5e-63 WQ51_03320 S cog cog4835
PGNNCGIA_00389 1.3e-146 XK27_08360 S EDD domain protein, DegV family
PGNNCGIA_00390 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGNNCGIA_00391 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGNNCGIA_00392 0.0 yfmR S abc transporter atp-binding protein
PGNNCGIA_00393 5.9e-27 U response to pH
PGNNCGIA_00394 1.6e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PGNNCGIA_00395 4.7e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PGNNCGIA_00397 1.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PGNNCGIA_00398 2.9e-280 S Psort location CytoplasmicMembrane, score
PGNNCGIA_00399 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PGNNCGIA_00400 3.3e-74 K DNA-binding transcription factor activity
PGNNCGIA_00401 0.0 lmrA1 V abc transporter atp-binding protein
PGNNCGIA_00402 0.0 lmrA2 V abc transporter atp-binding protein
PGNNCGIA_00403 4.3e-112 K Acetyltransferase (GNAT) family
PGNNCGIA_00404 5.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
PGNNCGIA_00405 8.3e-117 T response regulator
PGNNCGIA_00406 5.4e-215 sptS 2.7.13.3 T Histidine kinase
PGNNCGIA_00407 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PGNNCGIA_00408 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGNNCGIA_00409 3.2e-158 cvfB S Protein conserved in bacteria
PGNNCGIA_00410 3.7e-34 yozE S Belongs to the UPF0346 family
PGNNCGIA_00411 5.1e-128 sip M LysM domain protein
PGNNCGIA_00412 4.4e-189 phoH T phosphate starvation-inducible protein PhoH
PGNNCGIA_00416 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGNNCGIA_00417 1.5e-160 S reductase
PGNNCGIA_00418 1.8e-167 K transcriptional regulator (lysR family)
PGNNCGIA_00419 5.5e-106 S CAAX amino terminal protease family protein
PGNNCGIA_00420 3.2e-262 S Glucan-binding protein C
PGNNCGIA_00421 2.3e-165 coiA 3.6.4.12 S Competence protein
PGNNCGIA_00422 0.0 pepF E oligoendopeptidase F
PGNNCGIA_00423 3.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
PGNNCGIA_00424 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
PGNNCGIA_00425 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PGNNCGIA_00426 1.5e-83 yxjI S LURP-one-related
PGNNCGIA_00427 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGNNCGIA_00428 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PGNNCGIA_00430 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PGNNCGIA_00431 1.9e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PGNNCGIA_00432 6.1e-224 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PGNNCGIA_00433 1.3e-185 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGNNCGIA_00434 1.1e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGNNCGIA_00435 8.2e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PGNNCGIA_00436 5.5e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PGNNCGIA_00437 8.8e-135 yxkH G deacetylase
PGNNCGIA_00438 3.4e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PGNNCGIA_00439 4.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGNNCGIA_00440 3.3e-150 rarD S Transporter
PGNNCGIA_00441 3.7e-15 T peptidase
PGNNCGIA_00442 3e-14 coiA 3.6.4.12 S Competence protein
PGNNCGIA_00443 1.3e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGNNCGIA_00444 1.6e-42
PGNNCGIA_00445 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGNNCGIA_00446 3.5e-43 M1-386
PGNNCGIA_00447 2.8e-85
PGNNCGIA_00448 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGNNCGIA_00449 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
PGNNCGIA_00450 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGNNCGIA_00451 1.3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGNNCGIA_00452 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGNNCGIA_00453 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGNNCGIA_00454 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGNNCGIA_00455 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PGNNCGIA_00456 3.5e-217 ftsW D Belongs to the SEDS family
PGNNCGIA_00457 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGNNCGIA_00458 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGNNCGIA_00459 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGNNCGIA_00461 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGNNCGIA_00462 1.3e-159 holB 2.7.7.7 L dna polymerase iii
PGNNCGIA_00463 1.3e-132 yaaT S stage 0 sporulation protein
PGNNCGIA_00464 1.2e-54 yabA L Involved in initiation control of chromosome replication
PGNNCGIA_00465 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGNNCGIA_00466 4.3e-228 amt P Ammonium Transporter
PGNNCGIA_00467 1.1e-51 glnB K Belongs to the P(II) protein family
PGNNCGIA_00468 4.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
PGNNCGIA_00469 4.3e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PGNNCGIA_00470 7.6e-81 S Bacterial inner membrane protein
PGNNCGIA_00471 6.1e-114 3.4.17.14, 3.5.1.28 NU amidase activity
PGNNCGIA_00472 1.5e-292 nptA P COG1283 Na phosphate symporter
PGNNCGIA_00473 1e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGNNCGIA_00474 8.1e-219 S membrane
PGNNCGIA_00475 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PGNNCGIA_00476 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PGNNCGIA_00477 1.7e-38 ynzC S UPF0291 protein
PGNNCGIA_00478 6.7e-254 cycA E permease
PGNNCGIA_00479 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGNNCGIA_00480 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PGNNCGIA_00481 1.2e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGNNCGIA_00485 3.4e-69 K Helix-turn-helix
PGNNCGIA_00487 4.7e-168 fhuR K transcriptional regulator (lysR family)
PGNNCGIA_00488 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGNNCGIA_00489 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGNNCGIA_00490 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGNNCGIA_00491 1.6e-222 pyrP F uracil Permease
PGNNCGIA_00492 6.5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PGNNCGIA_00493 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PGNNCGIA_00494 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PGNNCGIA_00495 2.5e-122 2.1.1.223 S Putative SAM-dependent methyltransferase
PGNNCGIA_00496 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGNNCGIA_00497 3.4e-121 macB V ABC transporter, ATP-binding protein
PGNNCGIA_00498 1.4e-202 V permease protein
PGNNCGIA_00499 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGNNCGIA_00500 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGNNCGIA_00501 0.0 2.1.1.72 V DNA modification
PGNNCGIA_00505 9.8e-261 D ftsk spoiiie
PGNNCGIA_00506 5.7e-70
PGNNCGIA_00507 2.4e-16 S Domain of unknown function (DUF3173)
PGNNCGIA_00508 9.2e-228 L DNA integration
PGNNCGIA_00510 1.2e-28 M Plasmid recombination enzyme
PGNNCGIA_00512 2.7e-287 3.5.1.28 NU GBS Bsp-like repeat
PGNNCGIA_00514 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PGNNCGIA_00515 2e-16 L Transposase IS116 IS110 IS902
PGNNCGIA_00516 4.2e-226 2.7.13.3 T GHKL domain
PGNNCGIA_00517 5.9e-132 agrA KT Response regulator of the LytR AlgR family
PGNNCGIA_00519 2.8e-123 V AAA domain, putative AbiEii toxin, Type IV TA system
PGNNCGIA_00520 6.3e-124 S ABC-2 family transporter protein
PGNNCGIA_00521 1.4e-79
PGNNCGIA_00522 3.3e-105 T Transcriptional regulatory protein, C terminal
PGNNCGIA_00523 9.8e-160 2.7.13.3 T Histidine kinase
PGNNCGIA_00524 5.9e-36 K Helix-turn-helix
PGNNCGIA_00525 1.1e-38 D LPXTG cell wall anchor motif
PGNNCGIA_00527 2.3e-96 amiB 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PGNNCGIA_00529 4.9e-71
PGNNCGIA_00532 5e-17 S Domain of unknown function (DUF3173)
PGNNCGIA_00533 2e-147 L Phage integrase SAM-like domain
PGNNCGIA_00534 0.0 mdlB V abc transporter atp-binding protein
PGNNCGIA_00535 0.0 lmrA V abc transporter atp-binding protein
PGNNCGIA_00536 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PGNNCGIA_00537 1.4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PGNNCGIA_00538 3.8e-211 T signal transduction protein with a C-terminal ATPase domain
PGNNCGIA_00539 6.4e-128 rr02 KT response regulator
PGNNCGIA_00540 7.1e-164 V ABC transporter
PGNNCGIA_00541 1.3e-120 sagI S ABC-2 type transporter
PGNNCGIA_00543 2.6e-196 yceA S Belongs to the UPF0176 family
PGNNCGIA_00544 1e-27 XK27_00085 K Transcriptional
PGNNCGIA_00545 8.9e-20
PGNNCGIA_00546 5.9e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
PGNNCGIA_00547 2.3e-114 S VIT family
PGNNCGIA_00548 2.8e-140 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGNNCGIA_00549 8.5e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PGNNCGIA_00550 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PGNNCGIA_00553 3e-142 E Alpha beta hydrolase
PGNNCGIA_00554 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGNNCGIA_00555 7.1e-153 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PGNNCGIA_00556 9.6e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PGNNCGIA_00557 8e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PGNNCGIA_00558 8.6e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGNNCGIA_00559 6.4e-151 V ABC transporter, ATP-binding protein
PGNNCGIA_00560 2.9e-51 S ABC-2 family transporter protein
PGNNCGIA_00561 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PGNNCGIA_00562 9.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGNNCGIA_00563 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PGNNCGIA_00564 1.1e-24
PGNNCGIA_00565 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGNNCGIA_00566 0.0 U protein secretion
PGNNCGIA_00567 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PGNNCGIA_00568 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PGNNCGIA_00569 6.8e-10
PGNNCGIA_00570 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGNNCGIA_00571 1.1e-159 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGNNCGIA_00572 1.6e-199 S Protein of unknown function (DUF3114)
PGNNCGIA_00573 4.1e-29 pspC KT PspC domain protein
PGNNCGIA_00574 5.2e-119 yqfA K protein, Hemolysin III
PGNNCGIA_00575 1.1e-77 K hmm pf08876
PGNNCGIA_00576 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PGNNCGIA_00577 1e-210 mvaS 2.3.3.10 I synthase
PGNNCGIA_00578 5.5e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGNNCGIA_00579 1.1e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGNNCGIA_00580 9.7e-22
PGNNCGIA_00581 9.8e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGNNCGIA_00582 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PGNNCGIA_00583 1.8e-240 mmuP E amino acid
PGNNCGIA_00584 2.4e-170 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PGNNCGIA_00585 2.2e-30 S Domain of unknown function (DUF1912)
PGNNCGIA_00586 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
PGNNCGIA_00587 2.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGNNCGIA_00588 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGNNCGIA_00590 1.4e-10
PGNNCGIA_00591 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGNNCGIA_00592 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
PGNNCGIA_00593 1.4e-15 S Protein of unknown function (DUF2969)
PGNNCGIA_00596 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
PGNNCGIA_00599 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
PGNNCGIA_00600 6.4e-117 M Pfam SNARE associated Golgi protein
PGNNCGIA_00601 8.6e-229 murN 2.3.2.16 V FemAB family
PGNNCGIA_00602 1.4e-170 S oxidoreductase
PGNNCGIA_00603 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
PGNNCGIA_00604 4.3e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PGNNCGIA_00605 0.0 clpE O Belongs to the ClpA ClpB family
PGNNCGIA_00606 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGNNCGIA_00607 1e-34 ykuJ S protein conserved in bacteria
PGNNCGIA_00608 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PGNNCGIA_00609 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_00610 4.5e-77 feoA P FeoA domain protein
PGNNCGIA_00611 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PGNNCGIA_00612 1.7e-08
PGNNCGIA_00613 1.5e-149 I Alpha/beta hydrolase family
PGNNCGIA_00614 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGNNCGIA_00615 8.6e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGNNCGIA_00616 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PGNNCGIA_00617 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGNNCGIA_00618 1.8e-76 licT K antiterminator
PGNNCGIA_00619 4.7e-46 licT K antiterminator
PGNNCGIA_00620 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGNNCGIA_00621 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PGNNCGIA_00622 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGNNCGIA_00623 1.1e-144 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGNNCGIA_00624 2.6e-98 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGNNCGIA_00625 1.9e-220 mdtG EGP Major facilitator Superfamily
PGNNCGIA_00626 2e-33 secG U Preprotein translocase subunit SecG
PGNNCGIA_00627 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGNNCGIA_00628 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PGNNCGIA_00629 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGNNCGIA_00630 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PGNNCGIA_00631 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PGNNCGIA_00632 2.4e-181 ccpA K Catabolite control protein A
PGNNCGIA_00633 3.6e-199 yyaQ S YjbR
PGNNCGIA_00634 6.4e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PGNNCGIA_00635 3.3e-77 yueI S Protein of unknown function (DUF1694)
PGNNCGIA_00636 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGNNCGIA_00637 1.2e-25 WQ51_00785
PGNNCGIA_00638 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PGNNCGIA_00639 1.7e-218 ywbD 2.1.1.191 J Methyltransferase
PGNNCGIA_00640 4.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PGNNCGIA_00641 2.6e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGNNCGIA_00642 1.7e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PGNNCGIA_00643 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGNNCGIA_00644 2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PGNNCGIA_00645 4.2e-53 yheA S Belongs to the UPF0342 family
PGNNCGIA_00646 1.7e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGNNCGIA_00647 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PGNNCGIA_00648 2.2e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGNNCGIA_00649 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
PGNNCGIA_00650 2.3e-246 msrR K Transcriptional regulator
PGNNCGIA_00651 3.2e-151 ydiA P C4-dicarboxylate transporter malic acid transport protein
PGNNCGIA_00652 1.5e-200 I acyl-CoA dehydrogenase
PGNNCGIA_00653 2e-97 mip S hydroperoxide reductase activity
PGNNCGIA_00654 5.2e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGNNCGIA_00655 7.6e-36 S Pentapeptide repeat protein
PGNNCGIA_00656 6.3e-18
PGNNCGIA_00657 2e-38 K acetyltransferase
PGNNCGIA_00659 4.1e-12
PGNNCGIA_00661 1.4e-11 L Resolvase, N terminal domain
PGNNCGIA_00662 3e-113 K Psort location Cytoplasmic, score
PGNNCGIA_00663 1.3e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGNNCGIA_00664 3.7e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
PGNNCGIA_00665 1.1e-204 yeaN P transporter
PGNNCGIA_00666 6.8e-153 yitS S EDD domain protein, DegV family
PGNNCGIA_00667 9.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
PGNNCGIA_00668 5.4e-110 cutC P Participates in the control of copper homeostasis
PGNNCGIA_00670 7.1e-21 S Domain of unknown function (DUF4767)
PGNNCGIA_00671 3.2e-293 norB P Major facilitator superfamily
PGNNCGIA_00672 3.6e-94 tetR K transcriptional regulator
PGNNCGIA_00673 4e-153 S Domain of unknown function (DUF4300)
PGNNCGIA_00674 3.4e-127 V CAAX protease self-immunity
PGNNCGIA_00675 4.1e-155 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGNNCGIA_00676 7.1e-133 fecE 3.6.3.34 HP ABC transporter
PGNNCGIA_00677 1e-171 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PGNNCGIA_00678 2.4e-119 ybbA S Putative esterase
PGNNCGIA_00679 2.4e-47
PGNNCGIA_00680 2.8e-121 V CAAX protease self-immunity
PGNNCGIA_00681 6.8e-11
PGNNCGIA_00683 1.5e-57 S Protein of unknown function (DUF1722)
PGNNCGIA_00684 8.8e-65 yqeB S Pyrimidine dimer DNA glycosylase
PGNNCGIA_00686 3.6e-50
PGNNCGIA_00687 7.5e-93 S CAAX protease self-immunity
PGNNCGIA_00688 2.7e-42 estA E GDSL-like Lipase/Acylhydrolase
PGNNCGIA_00689 3.5e-42 estA E GDSL-like Lipase/Acylhydrolase
PGNNCGIA_00690 3.8e-100
PGNNCGIA_00691 1.3e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
PGNNCGIA_00692 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PGNNCGIA_00693 1.9e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGNNCGIA_00694 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGNNCGIA_00695 1.3e-169 S CRISPR-associated protein Csn2 subfamily St
PGNNCGIA_00696 4.9e-148 ycgQ S TIGR03943 family
PGNNCGIA_00697 5.4e-156 XK27_03015 S permease
PGNNCGIA_00699 0.0 yhgF K Transcriptional accessory protein
PGNNCGIA_00700 3.9e-83 ydcK S Belongs to the SprT family
PGNNCGIA_00701 2.2e-41 pspC KT PspC domain
PGNNCGIA_00702 3.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGNNCGIA_00703 2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGNNCGIA_00704 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGNNCGIA_00705 1.9e-66 ytxH S General stress protein
PGNNCGIA_00707 8.9e-178 yegQ O Peptidase U32
PGNNCGIA_00708 7.5e-252 yegQ O Peptidase U32
PGNNCGIA_00709 3e-85 bioY S biotin synthase
PGNNCGIA_00711 1.1e-33 XK27_12190 S protein conserved in bacteria
PGNNCGIA_00712 3.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
PGNNCGIA_00713 8.7e-13
PGNNCGIA_00714 4.2e-10
PGNNCGIA_00715 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PGNNCGIA_00716 3.7e-137 M LysM domain
PGNNCGIA_00717 8.4e-23
PGNNCGIA_00718 5.2e-175 S hydrolase
PGNNCGIA_00719 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PGNNCGIA_00720 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGNNCGIA_00721 1.9e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PGNNCGIA_00722 1.3e-26 P Hemerythrin HHE cation binding domain protein
PGNNCGIA_00723 2.1e-157 5.2.1.8 G hydrolase
PGNNCGIA_00724 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGNNCGIA_00725 4e-212 MA20_36090 S Protein of unknown function (DUF2974)
PGNNCGIA_00726 7.9e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGNNCGIA_00727 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
PGNNCGIA_00728 2.2e-116 hsdM 2.1.1.72 V type I restriction-modification system
PGNNCGIA_00729 8.1e-154 S KilA-N
PGNNCGIA_00730 1.1e-25
PGNNCGIA_00731 5.1e-190 ybl78 L Transcriptional regulator
PGNNCGIA_00732 9.6e-75 S Protein of unknown function (DUF3801)
PGNNCGIA_00733 0.0 U Type IV secretory system Conjugative DNA transfer
PGNNCGIA_00734 6.4e-101 K Psort location Cytoplasmic, score
PGNNCGIA_00735 1.4e-50 L single-stranded DNA binding
PGNNCGIA_00736 1.6e-29 S Maff2 family
PGNNCGIA_00737 2.3e-151
PGNNCGIA_00738 1.1e-40
PGNNCGIA_00739 2.8e-64 S PrgI family protein
PGNNCGIA_00740 0.0 U AAA-like domain
PGNNCGIA_00741 0.0 M this gene contains a nucleotide ambiguity which may be the result of a sequencing error
PGNNCGIA_00742 5.5e-12
PGNNCGIA_00743 1.3e-120 traB S Domain of unknown function (DUF4366)
PGNNCGIA_00744 6.8e-301 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGNNCGIA_00745 6.8e-165 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
PGNNCGIA_00746 0.0 L SNF2 family N-terminal domain
PGNNCGIA_00747 2.1e-49 L the current gene model (or a revised gene model) may contain a
PGNNCGIA_00748 2e-107 L Psort location Cytoplasmic, score
PGNNCGIA_00749 3e-31 K Transcriptional regulator
PGNNCGIA_00750 3.4e-199 haeIIIM 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PGNNCGIA_00751 1e-181 L HaeIII restriction endonuclease
PGNNCGIA_00752 5.6e-219 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PGNNCGIA_00753 9.9e-241 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
PGNNCGIA_00754 3.8e-238 U Relaxase/Mobilisation nuclease domain
PGNNCGIA_00755 2.7e-58 S the current gene model (or a revised gene model) may contain a frame shift
PGNNCGIA_00756 7.5e-42 K DNA-binding transcription factor activity
PGNNCGIA_00757 1.3e-67 K DNA-templated transcription, initiation
PGNNCGIA_00758 1.2e-59 K GntR family transcriptional regulator
PGNNCGIA_00759 3.7e-154 V abc transporter atp-binding protein
PGNNCGIA_00760 7.5e-96 P ABC-2 family transporter protein
PGNNCGIA_00762 2.3e-53 S Bacterial protein of unknown function (DUF961)
PGNNCGIA_00763 1.1e-14 S Bacterial protein of unknown function (DUF961)
PGNNCGIA_00764 3.7e-265 D Domain of unknown function DUF87
PGNNCGIA_00765 3e-234 K Replication initiation factor
PGNNCGIA_00766 4.3e-22 K Replication initiation factor
PGNNCGIA_00767 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
PGNNCGIA_00768 3.6e-16
PGNNCGIA_00769 1.3e-237 L Transposase
PGNNCGIA_00770 7.2e-39
PGNNCGIA_00771 2.1e-125 racA K helix_turn_helix, mercury resistance
PGNNCGIA_00772 4.5e-18
PGNNCGIA_00773 7.3e-308 L overlaps another CDS with the same product name
PGNNCGIA_00774 7.6e-297 L overlaps another CDS with the same product name
PGNNCGIA_00775 8.4e-255 L overlaps another CDS with the same product name
PGNNCGIA_00776 1.2e-152 hsdM 2.1.1.72 V N-6 DNA Methylase
PGNNCGIA_00777 3.4e-137 3.1.21.3 V Type I restriction modification DNA specificity domain
PGNNCGIA_00778 1.7e-135
PGNNCGIA_00779 9.1e-58
PGNNCGIA_00780 1.7e-54
PGNNCGIA_00781 6.7e-193 higA K Pfam:DUF955
PGNNCGIA_00782 2.9e-133 S double-stranded DNA endodeoxyribonuclease activity
PGNNCGIA_00783 0.0 2.4.1.21 GT5 M Right handed beta helix region
PGNNCGIA_00784 1.7e-174 spd F DNA RNA non-specific endonuclease
PGNNCGIA_00785 7.7e-92 lemA S LemA family
PGNNCGIA_00786 1.7e-133 htpX O Belongs to the peptidase M48B family
PGNNCGIA_00787 1.7e-119 sirR K iron dependent repressor
PGNNCGIA_00788 2.1e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
PGNNCGIA_00789 7.8e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
PGNNCGIA_00790 8.1e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
PGNNCGIA_00791 7.6e-75 S Psort location CytoplasmicMembrane, score
PGNNCGIA_00792 5.6e-65 S Domain of unknown function (DUF4430)
PGNNCGIA_00793 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PGNNCGIA_00794 5.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PGNNCGIA_00795 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PGNNCGIA_00796 5.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PGNNCGIA_00797 2.9e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PGNNCGIA_00798 1.1e-89 dps P Belongs to the Dps family
PGNNCGIA_00799 3.4e-79 perR P Belongs to the Fur family
PGNNCGIA_00800 7.1e-27 yqgQ S protein conserved in bacteria
PGNNCGIA_00801 2.7e-177 glk 2.7.1.2 G Glucokinase
PGNNCGIA_00802 0.0 typA T GTP-binding protein TypA
PGNNCGIA_00804 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGNNCGIA_00805 7.3e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGNNCGIA_00806 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGNNCGIA_00807 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGNNCGIA_00808 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGNNCGIA_00809 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PGNNCGIA_00810 2.2e-86 sepF D cell septum assembly
PGNNCGIA_00811 5e-30 yggT D integral membrane protein
PGNNCGIA_00812 2.7e-143 ylmH S conserved protein, contains S4-like domain
PGNNCGIA_00813 8.4e-138 divIVA D Cell division initiation protein
PGNNCGIA_00814 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGNNCGIA_00815 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGNNCGIA_00816 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGNNCGIA_00817 6.5e-34 nrdH O Glutaredoxin
PGNNCGIA_00818 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PGNNCGIA_00819 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PGNNCGIA_00820 8.8e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
PGNNCGIA_00821 3e-38 ptsH G phosphocarrier protein Hpr
PGNNCGIA_00822 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGNNCGIA_00823 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PGNNCGIA_00824 3.9e-161 XK27_05670 S Putative esterase
PGNNCGIA_00825 2.7e-153 XK27_05675 S Esterase
PGNNCGIA_00826 3.2e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
PGNNCGIA_00827 4.3e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
PGNNCGIA_00828 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PGNNCGIA_00829 0.0 uup S abc transporter atp-binding protein
PGNNCGIA_00830 1.6e-39 MA20_06245 S yiaA/B two helix domain
PGNNCGIA_00831 5.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
PGNNCGIA_00832 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGNNCGIA_00833 1.4e-147 cobQ S glutamine amidotransferase
PGNNCGIA_00834 6.4e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PGNNCGIA_00835 1.4e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGNNCGIA_00836 1.2e-161 ybbR S Protein conserved in bacteria
PGNNCGIA_00837 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGNNCGIA_00838 1.8e-66 gtrA S GtrA-like protein
PGNNCGIA_00839 4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
PGNNCGIA_00840 9.6e-141 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGNNCGIA_00841 3.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
PGNNCGIA_00842 1.3e-193 yurR 1.4.5.1 E oxidoreductase
PGNNCGIA_00843 3.1e-256 S phospholipase Carboxylesterase
PGNNCGIA_00844 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PGNNCGIA_00845 7e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PGNNCGIA_00846 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGNNCGIA_00848 1.7e-30 KT response to antibiotic
PGNNCGIA_00849 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
PGNNCGIA_00850 2.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
PGNNCGIA_00851 1.5e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGNNCGIA_00852 3.5e-117 ylfI S tigr01906
PGNNCGIA_00853 7.4e-135 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PGNNCGIA_00854 1.6e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PGNNCGIA_00855 7.8e-59 XK27_08085
PGNNCGIA_00856 4.6e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGNNCGIA_00857 4.1e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PGNNCGIA_00858 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PGNNCGIA_00859 5.6e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGNNCGIA_00860 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PGNNCGIA_00861 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGNNCGIA_00862 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGNNCGIA_00863 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGNNCGIA_00864 4.7e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PGNNCGIA_00865 3.4e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PGNNCGIA_00867 1.8e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
PGNNCGIA_00868 2.4e-144 P molecular chaperone
PGNNCGIA_00869 2.6e-95 S Carbohydrate-binding domain-containing protein Cthe_2159
PGNNCGIA_00870 3e-179 XK27_08075 M glycosyl transferase family 2
PGNNCGIA_00871 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_00872 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_00873 1.9e-178 L Transposase
PGNNCGIA_00874 8.1e-88 tag 3.2.2.20 L glycosylase
PGNNCGIA_00875 4.9e-41 S Sugar efflux transporter for intercellular exchange
PGNNCGIA_00876 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_00877 2.4e-235 rodA D Belongs to the SEDS family
PGNNCGIA_00878 1.9e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGNNCGIA_00879 1.4e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PGNNCGIA_00880 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGNNCGIA_00881 1.4e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGNNCGIA_00882 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
PGNNCGIA_00883 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PGNNCGIA_00884 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGNNCGIA_00885 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGNNCGIA_00886 1.3e-125 dnaD
PGNNCGIA_00887 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGNNCGIA_00889 1.5e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGNNCGIA_00890 1.8e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGNNCGIA_00891 1.9e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGNNCGIA_00892 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PGNNCGIA_00893 8.3e-73 argR K Regulates arginine biosynthesis genes
PGNNCGIA_00894 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
PGNNCGIA_00895 4.4e-144 DegV S DegV family
PGNNCGIA_00896 4.6e-160 ypmR E COG2755 Lysophospholipase L1 and related esterases
PGNNCGIA_00897 1.8e-96 ypmS S Protein conserved in bacteria
PGNNCGIA_00898 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGNNCGIA_00900 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PGNNCGIA_00901 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGNNCGIA_00902 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGNNCGIA_00903 3.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PGNNCGIA_00904 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGNNCGIA_00905 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGNNCGIA_00906 0.0 dnaE 2.7.7.7 L DNA polymerase
PGNNCGIA_00907 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PGNNCGIA_00908 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PGNNCGIA_00909 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
PGNNCGIA_00910 1.3e-18 S Domain of unknown function (DUF4649)
PGNNCGIA_00911 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
PGNNCGIA_00912 1.7e-138 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PGNNCGIA_00913 3.1e-136 XK27_08845 S abc transporter atp-binding protein
PGNNCGIA_00914 4.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGNNCGIA_00915 3.6e-148 estA CE1 S Esterase
PGNNCGIA_00916 6.7e-125 XK27_08875 O Zinc-dependent metalloprotease
PGNNCGIA_00917 2.8e-18 XK27_08880
PGNNCGIA_00918 1e-75 fld C Flavodoxin
PGNNCGIA_00919 3e-279 clcA P Chloride transporter, ClC family
PGNNCGIA_00920 4.7e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PGNNCGIA_00921 2.8e-211 XK27_05110 P Chloride transporter ClC family
PGNNCGIA_00922 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGNNCGIA_00925 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
PGNNCGIA_00926 1.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGNNCGIA_00927 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PGNNCGIA_00928 5.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGNNCGIA_00929 9.6e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGNNCGIA_00930 2.7e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGNNCGIA_00931 1.8e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
PGNNCGIA_00932 1.1e-143
PGNNCGIA_00933 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
PGNNCGIA_00934 3e-270 pelF GT4 M Domain of unknown function (DUF3492)
PGNNCGIA_00935 1.1e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
PGNNCGIA_00936 1.3e-222 cotH M CotH kinase protein
PGNNCGIA_00937 6.7e-96 P VTC domain
PGNNCGIA_00938 9.2e-84 S membrane
PGNNCGIA_00939 1.2e-133 G Domain of unknown function (DUF4832)
PGNNCGIA_00940 3.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PGNNCGIA_00942 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGNNCGIA_00943 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
PGNNCGIA_00944 3.2e-153 endA F DNA RNA non-specific endonuclease
PGNNCGIA_00945 2.9e-111 tcyB_2 P ABC transporter (permease)
PGNNCGIA_00946 1.9e-116 gltJ P ABC transporter (Permease
PGNNCGIA_00947 1.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGNNCGIA_00948 1.9e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_00949 7.9e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_00950 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGNNCGIA_00951 9.2e-220 vicK 2.7.13.3 T Histidine kinase
PGNNCGIA_00952 6.6e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PGNNCGIA_00953 1.3e-57 S Protein of unknown function (DUF454)
PGNNCGIA_00954 3.9e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PGNNCGIA_00955 4.6e-146 yidA S hydrolases of the HAD superfamily
PGNNCGIA_00956 3.1e-140 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PGNNCGIA_00957 5.3e-68 ywiB S Domain of unknown function (DUF1934)
PGNNCGIA_00958 0.0 pacL 3.6.3.8 P cation transport ATPase
PGNNCGIA_00959 1.3e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PGNNCGIA_00960 1.7e-156 yjjH S Calcineurin-like phosphoesterase
PGNNCGIA_00961 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGNNCGIA_00962 1.3e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGNNCGIA_00963 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PGNNCGIA_00964 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PGNNCGIA_00965 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGNNCGIA_00966 5.6e-177 yubA S permease
PGNNCGIA_00967 3.1e-223 G COG0457 FOG TPR repeat
PGNNCGIA_00968 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PGNNCGIA_00969 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PGNNCGIA_00970 2e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PGNNCGIA_00971 9.6e-86 ebsA S Family of unknown function (DUF5322)
PGNNCGIA_00972 2.5e-17 M LysM domain
PGNNCGIA_00973 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PGNNCGIA_00974 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGNNCGIA_00975 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PGNNCGIA_00976 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGNNCGIA_00977 2.5e-83 XK27_03610 K Gnat family
PGNNCGIA_00978 1.2e-91 yybC
PGNNCGIA_00979 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PGNNCGIA_00980 1.3e-273 pepV 3.5.1.18 E Dipeptidase
PGNNCGIA_00981 5.5e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
PGNNCGIA_00982 1.2e-225 V Glucan-binding protein C
PGNNCGIA_00983 3.7e-252 V Glucan-binding protein C
PGNNCGIA_00984 4.3e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGNNCGIA_00985 8.9e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGNNCGIA_00986 3.2e-95 S Protein of unknown function (DUF1697)
PGNNCGIA_00987 1.1e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PGNNCGIA_00988 1.7e-171 clcA_2 P Chloride transporter, ClC family
PGNNCGIA_00989 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
PGNNCGIA_00990 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PGNNCGIA_00991 3.6e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PGNNCGIA_00992 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PGNNCGIA_00993 3.8e-109 cps4C M biosynthesis protein
PGNNCGIA_00994 1.8e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
PGNNCGIA_00995 4.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PGNNCGIA_00996 2.4e-220 rgpAc GT4 M group 1 family protein
PGNNCGIA_00997 1.4e-212 wcoF M Glycosyltransferase, group 1 family protein
PGNNCGIA_00998 7.1e-118 Z012_10770 M Domain of unknown function (DUF1919)
PGNNCGIA_00999 2.6e-164
PGNNCGIA_01000 1.3e-172 M Glycosyltransferase like family 2
PGNNCGIA_01001 1.5e-126 cps3F
PGNNCGIA_01002 1.3e-244 epsU S Polysaccharide biosynthesis protein
PGNNCGIA_01003 2.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
PGNNCGIA_01004 1.6e-185 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
PGNNCGIA_01005 1.9e-176 wbbI M transferase activity, transferring glycosyl groups
PGNNCGIA_01007 1.7e-135 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PGNNCGIA_01008 8.2e-108 pgm G Belongs to the phosphoglycerate mutase family
PGNNCGIA_01009 3.7e-108 G Belongs to the phosphoglycerate mutase family
PGNNCGIA_01010 4e-107 G Belongs to the phosphoglycerate mutase family
PGNNCGIA_01011 1.5e-195 S hmm pf01594
PGNNCGIA_01012 1.4e-286 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PGNNCGIA_01013 4.9e-39 S granule-associated protein
PGNNCGIA_01014 2.3e-287 S unusual protein kinase
PGNNCGIA_01015 3.2e-99 estA E Lysophospholipase L1 and related esterases
PGNNCGIA_01016 1e-156 rssA S Phospholipase, patatin family
PGNNCGIA_01017 6.1e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PGNNCGIA_01018 9.3e-245 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PGNNCGIA_01019 1.6e-211 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGNNCGIA_01020 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGNNCGIA_01021 3.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGNNCGIA_01022 0.0 S the current gene model (or a revised gene model) may contain a frame shift
PGNNCGIA_01023 2.5e-223 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01024 6.5e-208 hpk9 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01025 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PGNNCGIA_01026 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGNNCGIA_01027 7.6e-210 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGNNCGIA_01028 0.0 lpdA 1.8.1.4 C Dehydrogenase
PGNNCGIA_01029 0.0 3.5.1.28 NU amidase activity
PGNNCGIA_01030 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PGNNCGIA_01031 3.3e-131 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PGNNCGIA_01032 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PGNNCGIA_01033 8.4e-146 ycdO P periplasmic lipoprotein involved in iron transport
PGNNCGIA_01034 6.2e-232 ycdB P peroxidase
PGNNCGIA_01035 1.7e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PGNNCGIA_01036 7.1e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGNNCGIA_01037 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PGNNCGIA_01038 4.7e-213 msmX P Belongs to the ABC transporter superfamily
PGNNCGIA_01039 9.8e-152 malG P ABC transporter (Permease
PGNNCGIA_01040 1.7e-249 malF P ABC transporter (Permease
PGNNCGIA_01041 3.9e-229 malX G ABC transporter
PGNNCGIA_01042 1e-171 malR K Transcriptional regulator
PGNNCGIA_01043 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PGNNCGIA_01044 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGNNCGIA_01045 1.9e-223 L Transposase
PGNNCGIA_01046 1.2e-38
PGNNCGIA_01047 6.1e-185 lplA 6.3.1.20 H Lipoate-protein ligase
PGNNCGIA_01048 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PGNNCGIA_01049 0.0 pepN 3.4.11.2 E aminopeptidase
PGNNCGIA_01050 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
PGNNCGIA_01051 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGNNCGIA_01052 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGNNCGIA_01053 9.1e-156 pstA P phosphate transport system permease
PGNNCGIA_01054 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PGNNCGIA_01055 5.8e-155 pstS P phosphate
PGNNCGIA_01056 4.8e-246 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PGNNCGIA_01057 5.5e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PGNNCGIA_01058 1e-44 yktA S Belongs to the UPF0223 family
PGNNCGIA_01059 6e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGNNCGIA_01060 7.4e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PGNNCGIA_01061 1.1e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGNNCGIA_01062 1.4e-240 XK27_04775 S hemerythrin HHE cation binding domain
PGNNCGIA_01063 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
PGNNCGIA_01064 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PGNNCGIA_01065 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGNNCGIA_01066 2.5e-138 S haloacid dehalogenase-like hydrolase
PGNNCGIA_01067 7.3e-239 metY 2.5.1.49 E o-acetylhomoserine
PGNNCGIA_01068 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PGNNCGIA_01069 9e-240 agcS E (Alanine) symporter
PGNNCGIA_01070 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGNNCGIA_01071 3.9e-176 bglC K Transcriptional regulator
PGNNCGIA_01072 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PGNNCGIA_01073 2.4e-81 yecS P ABC transporter (Permease
PGNNCGIA_01074 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
PGNNCGIA_01075 3.3e-240 nylA 3.5.1.4 J Belongs to the amidase family
PGNNCGIA_01076 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGNNCGIA_01077 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGNNCGIA_01080 1.4e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGNNCGIA_01081 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PGNNCGIA_01082 1e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PGNNCGIA_01083 4.4e-133 S TraX protein
PGNNCGIA_01084 2.8e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PGNNCGIA_01085 5.6e-278 S Psort location CytoplasmicMembrane, score
PGNNCGIA_01086 3.1e-232 dinF V Mate efflux family protein
PGNNCGIA_01087 7.8e-177 yclQ P ABC-type enterochelin transport system, periplasmic component
PGNNCGIA_01088 1.7e-56 S von Willebrand factor (vWF) type A domain
PGNNCGIA_01089 6.3e-70 S von Willebrand factor (vWF) type A domain
PGNNCGIA_01090 0.0 V Type III restriction enzyme, res subunit
PGNNCGIA_01091 1.4e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PGNNCGIA_01092 1.4e-133 2.4.2.3 F Phosphorylase superfamily
PGNNCGIA_01093 5.1e-105 K Bacterial regulatory proteins, tetR family
PGNNCGIA_01094 7.1e-179 ybhR V ABC transporter
PGNNCGIA_01095 4.8e-123 ybhF_2 V abc transporter atp-binding protein
PGNNCGIA_01096 1.4e-187 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
PGNNCGIA_01097 7.7e-197 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PGNNCGIA_01098 1.7e-157 czcD P cation diffusion facilitator family transporter
PGNNCGIA_01099 4.6e-100 K Transcriptional regulator, TetR family
PGNNCGIA_01100 1.1e-70 S Protein of unknown function with HXXEE motif
PGNNCGIA_01101 4.9e-46
PGNNCGIA_01102 3.1e-73 L Transposase
PGNNCGIA_01103 0.0 S Signal peptide protein, YSIRK family
PGNNCGIA_01104 2e-126 K response regulator
PGNNCGIA_01105 1.2e-175 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PGNNCGIA_01106 1.7e-148 cbiO2 P ABC transporter, ATP-binding protein
PGNNCGIA_01107 1e-156 P abc transporter atp-binding protein
PGNNCGIA_01108 1.8e-131 cbiQ P cobalt transport
PGNNCGIA_01109 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
PGNNCGIA_01110 1.2e-138 S Phenazine biosynthesis protein
PGNNCGIA_01111 4.4e-92 tetR K transcriptional regulator
PGNNCGIA_01112 8.6e-125 V abc transporter atp-binding protein
PGNNCGIA_01113 0.0 V ABC transporter (Permease
PGNNCGIA_01114 1.1e-34 L Integrase core domain protein
PGNNCGIA_01115 5.9e-109 magIII L Base excision DNA repair protein, HhH-GPD family
PGNNCGIA_01116 1e-263 proWX P ABC transporter
PGNNCGIA_01117 3.5e-129 proV E abc transporter atp-binding protein
PGNNCGIA_01118 9.1e-145 1.6.5.2 GM NmrA-like family
PGNNCGIA_01119 1.1e-67 mgrA K Transcriptional regulator, MarR family
PGNNCGIA_01120 2.5e-77 S Macro domain
PGNNCGIA_01121 1.1e-97 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
PGNNCGIA_01122 4.4e-26 C Pyridoxamine 5'-phosphate oxidase
PGNNCGIA_01123 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PGNNCGIA_01124 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PGNNCGIA_01127 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGNNCGIA_01129 1.8e-136 IQ Acetoin reductase
PGNNCGIA_01130 4.1e-44 pspE P Rhodanese-like protein
PGNNCGIA_01131 2.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PGNNCGIA_01132 1e-223 XK27_05470 E Methionine synthase
PGNNCGIA_01133 1.1e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PGNNCGIA_01134 5.2e-235 T PhoQ Sensor
PGNNCGIA_01135 1.4e-121 KT Transcriptional regulatory protein, C terminal
PGNNCGIA_01136 4.7e-146 S TraX protein
PGNNCGIA_01137 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGNNCGIA_01138 6.6e-156 dprA LU DNA protecting protein DprA
PGNNCGIA_01139 4e-162 GK ROK family
PGNNCGIA_01140 1.9e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGNNCGIA_01141 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGNNCGIA_01142 4.8e-128 K DNA-binding helix-turn-helix protein
PGNNCGIA_01143 6.6e-90 niaR S small molecule binding protein (contains 3H domain)
PGNNCGIA_01144 7e-87
PGNNCGIA_01145 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGNNCGIA_01146 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGNNCGIA_01147 2.7e-126 gntR1 K transcriptional
PGNNCGIA_01148 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PGNNCGIA_01149 4.7e-216 K Putative DNA-binding domain
PGNNCGIA_01150 3.3e-34 V ABC transporter transmembrane region
PGNNCGIA_01151 9.4e-08
PGNNCGIA_01152 2.8e-21 yozG K Transcriptional regulator
PGNNCGIA_01153 6.8e-10 S Protein of unknown function (DUF2975)
PGNNCGIA_01155 1.4e-13 S Sigma-70, region 4
PGNNCGIA_01156 2.6e-44
PGNNCGIA_01157 2e-197 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PGNNCGIA_01158 6.5e-52
PGNNCGIA_01159 5.5e-101 S Plasmid replication protein
PGNNCGIA_01160 1.9e-18 S Domain of unknown function (DUF3173)
PGNNCGIA_01161 2.7e-227 L Belongs to the 'phage' integrase family
PGNNCGIA_01162 8.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGNNCGIA_01163 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
PGNNCGIA_01164 6.7e-44
PGNNCGIA_01165 2.6e-51
PGNNCGIA_01166 1.6e-266 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGNNCGIA_01167 1.3e-156 aatB ET ABC transporter substrate-binding protein
PGNNCGIA_01168 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_01169 3.1e-105 artQ P ABC transporter (Permease
PGNNCGIA_01170 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
PGNNCGIA_01171 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGNNCGIA_01172 8.4e-165 cpsY K Transcriptional regulator
PGNNCGIA_01173 1e-125 mur1 3.4.17.14, 3.5.1.28 NU muramidase
PGNNCGIA_01174 5.9e-159 yeiH S Membrane
PGNNCGIA_01176 2.6e-09
PGNNCGIA_01177 6.8e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
PGNNCGIA_01178 7.9e-146 XK27_10720 D peptidase activity
PGNNCGIA_01179 3.6e-276 pepD E Dipeptidase
PGNNCGIA_01180 2.2e-160 whiA K May be required for sporulation
PGNNCGIA_01181 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PGNNCGIA_01182 2.2e-162 rapZ S Displays ATPase and GTPase activities
PGNNCGIA_01183 2.6e-135 yejC S cyclic nucleotide-binding protein
PGNNCGIA_01184 1.7e-186 D nuclear chromosome segregation
PGNNCGIA_01185 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PGNNCGIA_01186 7.9e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PGNNCGIA_01187 8.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
PGNNCGIA_01188 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PGNNCGIA_01189 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PGNNCGIA_01190 1.3e-19
PGNNCGIA_01191 1.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PGNNCGIA_01192 4.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PGNNCGIA_01193 1.1e-81 ypmB S Protein conserved in bacteria
PGNNCGIA_01194 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PGNNCGIA_01195 1.7e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PGNNCGIA_01196 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
PGNNCGIA_01197 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
PGNNCGIA_01198 1.6e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PGNNCGIA_01199 1.2e-191 tcsA S membrane
PGNNCGIA_01200 6.9e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PGNNCGIA_01201 1.2e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGNNCGIA_01202 3.6e-230 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PGNNCGIA_01203 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
PGNNCGIA_01204 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
PGNNCGIA_01205 1e-29 rpsT J Binds directly to 16S ribosomal RNA
PGNNCGIA_01206 3.9e-241 T PhoQ Sensor
PGNNCGIA_01207 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGNNCGIA_01208 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PGNNCGIA_01209 3.5e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PGNNCGIA_01210 1.7e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGNNCGIA_01211 4.1e-93 panT S ECF transporter, substrate-specific component
PGNNCGIA_01212 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PGNNCGIA_01213 1e-159 metF 1.5.1.20 E reductase
PGNNCGIA_01214 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PGNNCGIA_01216 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PGNNCGIA_01217 0.0 3.6.3.8 P cation transport ATPase
PGNNCGIA_01218 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGNNCGIA_01219 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGNNCGIA_01220 1.2e-235 dltB M Membrane protein involved in D-alanine export
PGNNCGIA_01221 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGNNCGIA_01222 0.0 XK27_10035 V abc transporter atp-binding protein
PGNNCGIA_01223 3.8e-291 yfiB1 V abc transporter atp-binding protein
PGNNCGIA_01224 9.2e-99 pvaA M lytic transglycosylase activity
PGNNCGIA_01225 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
PGNNCGIA_01226 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGNNCGIA_01227 1.4e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGNNCGIA_01228 3.9e-140 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGNNCGIA_01229 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGNNCGIA_01230 3e-110 tdk 2.7.1.21 F thymidine kinase
PGNNCGIA_01231 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PGNNCGIA_01232 1.1e-152 gst O Glutathione S-transferase
PGNNCGIA_01233 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PGNNCGIA_01234 4.6e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PGNNCGIA_01235 4.4e-45 rpmE2 J 50S ribosomal protein L31
PGNNCGIA_01236 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
PGNNCGIA_01237 1.3e-163 ypuA S secreted protein
PGNNCGIA_01238 3.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PGNNCGIA_01239 2.1e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PGNNCGIA_01240 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGNNCGIA_01241 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PGNNCGIA_01242 1.4e-256 noxE P NADH oxidase
PGNNCGIA_01243 1.1e-294 yfmM S abc transporter atp-binding protein
PGNNCGIA_01244 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
PGNNCGIA_01245 5.3e-153 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PGNNCGIA_01246 7e-84 S ECF-type riboflavin transporter, S component
PGNNCGIA_01248 6.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGNNCGIA_01249 1.2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PGNNCGIA_01251 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGNNCGIA_01252 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGNNCGIA_01253 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGNNCGIA_01254 3.8e-22 WQ51_00220 K Helix-turn-helix domain
PGNNCGIA_01255 9.1e-90 S Protein of unknown function (DUF3278)
PGNNCGIA_01256 0.0 smc D Required for chromosome condensation and partitioning
PGNNCGIA_01257 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGNNCGIA_01258 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGNNCGIA_01259 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGNNCGIA_01261 2e-291 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGNNCGIA_01262 1.1e-89 pat 2.3.1.183 M acetyltransferase
PGNNCGIA_01263 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGNNCGIA_01264 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PGNNCGIA_01265 4.2e-53
PGNNCGIA_01266 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGNNCGIA_01267 2.9e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PGNNCGIA_01268 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
PGNNCGIA_01269 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
PGNNCGIA_01270 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
PGNNCGIA_01271 1.9e-133 L Integrase
PGNNCGIA_01272 2e-202 S Protein of unknown function DUF262
PGNNCGIA_01273 2.1e-151 S Protein of unknown function DUF262
PGNNCGIA_01274 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGNNCGIA_01275 1.1e-79 3.4.21.89 S RDD family
PGNNCGIA_01276 1.8e-130 K sequence-specific DNA binding
PGNNCGIA_01277 1.6e-146 V ABC transporter, ATP-binding protein
PGNNCGIA_01278 7.8e-81 S ABC-2 family transporter protein
PGNNCGIA_01279 3.3e-33 K sequence-specific DNA binding
PGNNCGIA_01280 1.7e-124 K sequence-specific DNA binding
PGNNCGIA_01281 5.7e-15
PGNNCGIA_01282 3.5e-22
PGNNCGIA_01283 1.1e-87
PGNNCGIA_01284 1.7e-22
PGNNCGIA_01285 6.6e-142 S ABC-2 family transporter protein
PGNNCGIA_01286 2e-141 S ABC-2 family transporter protein
PGNNCGIA_01287 3.2e-186 S abc transporter atp-binding protein
PGNNCGIA_01288 2.4e-49 L COG1943 Transposase and inactivated derivatives
PGNNCGIA_01289 2.4e-99 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGNNCGIA_01290 7.1e-187 desK 2.7.13.3 T Histidine kinase
PGNNCGIA_01291 1.4e-133 yvfS V ABC-2 type transporter
PGNNCGIA_01292 4.1e-156 XK27_09825 V 'abc transporter, ATP-binding protein
PGNNCGIA_01295 5.7e-172 fabH 2.3.1.180 I synthase III
PGNNCGIA_01296 3.6e-238 6.2.1.30 H Coenzyme F390 synthetase
PGNNCGIA_01297 3e-153 gumP S Metallo-beta-lactamase superfamily
PGNNCGIA_01298 1.3e-179 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
PGNNCGIA_01299 5e-232 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
PGNNCGIA_01300 3.1e-107 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGNNCGIA_01301 1.6e-197 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
PGNNCGIA_01302 2.4e-100
PGNNCGIA_01303 6.7e-208 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
PGNNCGIA_01305 4.8e-233 anK3 G response to abiotic stimulus
PGNNCGIA_01306 0.0 hscC O Belongs to the heat shock protein 70 family
PGNNCGIA_01307 5.1e-165 yocS S Transporter
PGNNCGIA_01308 5.2e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PGNNCGIA_01309 2.6e-116 yvfS V Transporter
PGNNCGIA_01310 6.9e-156 XK27_09825 V abc transporter atp-binding protein
PGNNCGIA_01311 7e-15 liaI KT membrane
PGNNCGIA_01312 6.4e-29 liaI KT membrane
PGNNCGIA_01313 6.1e-93 XK27_05000 S metal cluster binding
PGNNCGIA_01314 0.0 V ABC transporter (permease)
PGNNCGIA_01315 2.5e-130 macB2 V ABC transporter, ATP-binding protein
PGNNCGIA_01316 5.9e-148 T Histidine kinase
PGNNCGIA_01317 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGNNCGIA_01318 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGNNCGIA_01319 1.9e-223 pbuX F xanthine permease
PGNNCGIA_01320 2.1e-280 V (ABC) transporter
PGNNCGIA_01321 5.4e-142 K sequence-specific DNA binding
PGNNCGIA_01322 1.8e-243 norM V Multidrug efflux pump
PGNNCGIA_01324 1.3e-176 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGNNCGIA_01325 3.5e-228 brnQ E Component of the transport system for branched-chain amino acids
PGNNCGIA_01326 1.9e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGNNCGIA_01327 1.7e-57 S Protein of unknown function (DUF3290)
PGNNCGIA_01328 6.4e-103 S Protein of unknown function (DUF421)
PGNNCGIA_01329 2.5e-13 csbD K CsbD-like
PGNNCGIA_01330 1.9e-105 S Carbohydrate-binding domain-containing protein Cthe_2159
PGNNCGIA_01331 5.7e-37 XK27_01300 S ASCH
PGNNCGIA_01332 2.2e-212 yfnA E amino acid
PGNNCGIA_01333 0.0 S dextransucrase activity
PGNNCGIA_01334 5.6e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PGNNCGIA_01335 2e-42 S Sugar efflux transporter for intercellular exchange
PGNNCGIA_01336 1.2e-203 P FtsX-like permease family
PGNNCGIA_01337 1.3e-122 V abc transporter atp-binding protein
PGNNCGIA_01338 6.9e-96 K WHG domain
PGNNCGIA_01339 3.7e-168 ydhF S Aldo keto reductase
PGNNCGIA_01340 1.1e-06 S Protein of unknown function (DUF3169)
PGNNCGIA_01341 2.5e-27 XK27_07105 K transcriptional
PGNNCGIA_01342 2.7e-27
PGNNCGIA_01343 2.2e-108 XK27_02070 S nitroreductase
PGNNCGIA_01344 1.4e-150 1.13.11.2 S glyoxalase
PGNNCGIA_01345 2.5e-77 ywnA K Transcriptional regulator
PGNNCGIA_01346 7.5e-155 E Alpha/beta hydrolase of unknown function (DUF915)
PGNNCGIA_01347 8.1e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGNNCGIA_01348 2.4e-167 bcrA V abc transporter atp-binding protein
PGNNCGIA_01349 5.8e-127 S ABC-2 family transporter protein
PGNNCGIA_01350 1.5e-09
PGNNCGIA_01351 6.7e-07 S Tetratricopeptide repeats
PGNNCGIA_01354 1.2e-128 T PhoQ Sensor
PGNNCGIA_01355 3.3e-121 T Xre family transcriptional regulator
PGNNCGIA_01356 1.1e-107 drgA C nitroreductase
PGNNCGIA_01357 1.6e-104 yoaK S Protein of unknown function (DUF1275)
PGNNCGIA_01358 4e-40 DJ nuclease activity
PGNNCGIA_01359 2.1e-29 XK27_10490
PGNNCGIA_01360 1.1e-158 yvgN C reductase
PGNNCGIA_01361 7.9e-107 S Tetratricopeptide repeat
PGNNCGIA_01362 0.0 lacL 3.2.1.23 G -beta-galactosidase
PGNNCGIA_01363 0.0 lacS G transporter
PGNNCGIA_01364 1.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PGNNCGIA_01365 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PGNNCGIA_01366 2.6e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PGNNCGIA_01367 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PGNNCGIA_01368 3.4e-175 galR K Transcriptional regulator
PGNNCGIA_01369 1.4e-303 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PGNNCGIA_01370 2.3e-216 vncS 2.7.13.3 T Histidine kinase
PGNNCGIA_01371 8.9e-116 K Response regulator receiver domain protein
PGNNCGIA_01372 3.1e-235 vex3 V Efflux ABC transporter, permease protein
PGNNCGIA_01373 7.3e-107 vex2 V abc transporter atp-binding protein
PGNNCGIA_01374 1e-213 vex1 V Efflux ABC transporter, permease protein
PGNNCGIA_01375 5.6e-283 XK27_07020 S Belongs to the UPF0371 family
PGNNCGIA_01377 1.4e-195 gldA 1.1.1.6 C glycerol dehydrogenase
PGNNCGIA_01378 1.1e-178 XK27_10475 S oxidoreductase
PGNNCGIA_01379 5.7e-59 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
PGNNCGIA_01380 9.9e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
PGNNCGIA_01381 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
PGNNCGIA_01382 1.6e-222 thrE K Psort location CytoplasmicMembrane, score
PGNNCGIA_01383 0.0 M Putative cell wall binding repeat
PGNNCGIA_01384 6.4e-35 S Immunity protein 41
PGNNCGIA_01385 1.8e-08 S Enterocin A Immunity
PGNNCGIA_01386 8.9e-187 mccF V LD-carboxypeptidase
PGNNCGIA_01387 1.8e-14 S integral membrane protein
PGNNCGIA_01388 2.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
PGNNCGIA_01389 4.8e-118 yhfC S Putative membrane peptidase family (DUF2324)
PGNNCGIA_01390 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_01392 2.1e-245 S dextransucrase activity
PGNNCGIA_01393 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_01394 0.0 S dextransucrase activity
PGNNCGIA_01395 0.0 S dextransucrase activity
PGNNCGIA_01396 2.2e-90 S dextransucrase activity
PGNNCGIA_01397 0.0 S dextransucrase activity
PGNNCGIA_01398 3.9e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PGNNCGIA_01399 1.2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PGNNCGIA_01400 1.6e-301 S dextransucrase activity
PGNNCGIA_01401 0.0 S dextransucrase activity
PGNNCGIA_01402 2.8e-175 S dextransucrase activity
PGNNCGIA_01403 0.0 M Putative cell wall binding repeat
PGNNCGIA_01404 3.4e-224 M Putative cell wall binding repeat
PGNNCGIA_01407 3.1e-112 XK27_00785 S CAAX protease self-immunity
PGNNCGIA_01408 2.2e-233 EGP Major facilitator Superfamily
PGNNCGIA_01409 5.5e-63 rmaI K Transcriptional regulator, MarR family
PGNNCGIA_01410 3e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
PGNNCGIA_01411 2e-135 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PGNNCGIA_01412 0.0 3.5.1.28 M domain protein
PGNNCGIA_01413 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PGNNCGIA_01414 5.4e-24
PGNNCGIA_01418 2.3e-10 sraP UW domain, Protein
PGNNCGIA_01420 1.9e-78 sraP UW Hep Hag repeat protein
PGNNCGIA_01421 5.2e-194 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
PGNNCGIA_01423 7.3e-186 nss M transferase activity, transferring glycosyl groups
PGNNCGIA_01424 3.6e-16 S Accessory secretory protein Sec, Asp5
PGNNCGIA_01425 2.6e-17 S Accessory secretory protein Sec Asp4
PGNNCGIA_01426 1.2e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGNNCGIA_01427 5.7e-283 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGNNCGIA_01428 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGNNCGIA_01429 1e-78 asp3 S Accessory Sec system protein Asp3
PGNNCGIA_01430 4.9e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PGNNCGIA_01431 1.4e-289 asp1 S Accessory Sec system protein Asp1
PGNNCGIA_01432 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PGNNCGIA_01433 0.0 M family 8
PGNNCGIA_01434 0.0 sbcC L ATPase involved in DNA repair
PGNNCGIA_01435 1.1e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PGNNCGIA_01436 0.0 GM domain, Protein
PGNNCGIA_01437 0.0 zmpB M signal peptide protein, YSIRK family
PGNNCGIA_01438 3.4e-30 L PFAM transposase IS116 IS110 IS902 family
PGNNCGIA_01439 2.2e-61 L Transposase
PGNNCGIA_01440 2.7e-24 L the current gene model (or a revised gene model) may contain a frame shift
PGNNCGIA_01441 1.3e-48 bipA Q Transposase
PGNNCGIA_01442 6.3e-37 M COG3209 Rhs family protein
PGNNCGIA_01445 0.0 M domain protein
PGNNCGIA_01446 8.9e-12
PGNNCGIA_01447 5.7e-190 XK27_10075 S abc transporter atp-binding protein
PGNNCGIA_01448 0.0 V abc transporter atp-binding protein
PGNNCGIA_01449 2.7e-297 V abc transporter atp-binding protein
PGNNCGIA_01450 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PGNNCGIA_01452 6.1e-285 S Protein of unknown function (DUF3114)
PGNNCGIA_01453 1e-96 2.3.1.128 K Acetyltransferase GNAT Family
PGNNCGIA_01454 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGNNCGIA_01455 2.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PGNNCGIA_01456 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
PGNNCGIA_01457 2.2e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PGNNCGIA_01458 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PGNNCGIA_01459 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PGNNCGIA_01460 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PGNNCGIA_01461 2.8e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PGNNCGIA_01462 2.7e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PGNNCGIA_01463 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGNNCGIA_01466 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGNNCGIA_01467 9.7e-170 vraS 2.7.13.3 T Histidine kinase
PGNNCGIA_01468 5.6e-116 yvqF S Membrane
PGNNCGIA_01469 1.1e-86 kcsA P Ion transport protein
PGNNCGIA_01471 2.3e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
PGNNCGIA_01472 2e-135 stp 3.1.3.16 T phosphatase
PGNNCGIA_01473 1.5e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGNNCGIA_01474 8.9e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGNNCGIA_01475 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGNNCGIA_01476 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PGNNCGIA_01477 5.7e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PGNNCGIA_01478 1e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGNNCGIA_01479 8.2e-143 XK27_02985 S overlaps another CDS with the same product name
PGNNCGIA_01480 1.4e-144 supH S overlaps another CDS with the same product name
PGNNCGIA_01481 2.8e-61 yvoA_1 K Transcriptional
PGNNCGIA_01482 5.4e-119 skfE V abc transporter atp-binding protein
PGNNCGIA_01483 9.9e-130 V Psort location CytoplasmicMembrane, score
PGNNCGIA_01484 1e-170 oppF P Belongs to the ABC transporter superfamily
PGNNCGIA_01485 4.6e-202 oppD P Belongs to the ABC transporter superfamily
PGNNCGIA_01486 3.5e-166 amiD P ABC transporter (Permease
PGNNCGIA_01487 7.8e-277 amiC P ABC transporter (Permease
PGNNCGIA_01488 6.2e-306 amiA E ABC transporter, substrate-binding protein, family 5
PGNNCGIA_01489 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PGNNCGIA_01490 4.8e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PGNNCGIA_01491 5.9e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PGNNCGIA_01492 4.9e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGNNCGIA_01493 3.9e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PGNNCGIA_01494 2.4e-101 yjbK S Adenylate cyclase
PGNNCGIA_01495 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGNNCGIA_01496 8.3e-207 iscS 2.8.1.7 E Cysteine desulfurase
PGNNCGIA_01497 8.2e-60 XK27_04120 S Putative amino acid metabolism
PGNNCGIA_01498 7.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGNNCGIA_01499 5.7e-129 puuD T peptidase C26
PGNNCGIA_01500 1.5e-118 radC E Belongs to the UPF0758 family
PGNNCGIA_01501 8.3e-280 rgpF M Rhamnan synthesis protein F
PGNNCGIA_01502 6.2e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PGNNCGIA_01503 4.4e-141 rgpC GM Transport permease protein
PGNNCGIA_01504 1.9e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
PGNNCGIA_01505 3.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
PGNNCGIA_01506 2.3e-221 GT4 M transferase activity, transferring glycosyl groups
PGNNCGIA_01507 1.2e-222 M Psort location CytoplasmicMembrane, score
PGNNCGIA_01508 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
PGNNCGIA_01509 1.2e-142 cpsIaJ S Glycosyltransferase like family 2
PGNNCGIA_01510 1.9e-122 S Glycosyltransferase like family 2
PGNNCGIA_01511 2.2e-192 amrA S membrane protein involved in the export of O-antigen and teichoic acid
PGNNCGIA_01512 2e-106 2.4.1.60 S Glycosyltransferase group 2 family protein
PGNNCGIA_01513 2.6e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
PGNNCGIA_01514 6.5e-125 ycbB S Glycosyl transferase family 2
PGNNCGIA_01515 8.4e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PGNNCGIA_01516 8e-217 S Predicted membrane protein (DUF2142)
PGNNCGIA_01517 1.5e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PGNNCGIA_01518 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PGNNCGIA_01519 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGNNCGIA_01520 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGNNCGIA_01521 8.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PGNNCGIA_01522 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PGNNCGIA_01523 3.8e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
PGNNCGIA_01524 4e-201 arcT 2.6.1.1 E Aminotransferase
PGNNCGIA_01525 3.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
PGNNCGIA_01526 2.4e-131 ET Belongs to the bacterial solute-binding protein 3 family
PGNNCGIA_01527 3.6e-79 mutT 3.6.1.55 F Nudix family
PGNNCGIA_01528 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGNNCGIA_01530 4.3e-164 S CAAX amino terminal protease family protein
PGNNCGIA_01531 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PGNNCGIA_01532 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_01533 1.7e-17 XK27_00735
PGNNCGIA_01534 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGNNCGIA_01535 1e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGNNCGIA_01536 7.5e-10 O ADP-ribosylglycohydrolase
PGNNCGIA_01537 2.1e-61 paaI Q protein possibly involved in aromatic compounds catabolism
PGNNCGIA_01538 2.4e-62 ycaO O OsmC-like protein
PGNNCGIA_01540 3.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
PGNNCGIA_01541 2.5e-07 N PFAM Uncharacterised protein family UPF0150
PGNNCGIA_01542 4.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
PGNNCGIA_01543 7.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGNNCGIA_01544 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGNNCGIA_01545 1.6e-94 3.1.3.18 S IA, variant 1
PGNNCGIA_01546 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PGNNCGIA_01547 3.5e-56 lrgA S Effector of murein hydrolase LrgA
PGNNCGIA_01549 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
PGNNCGIA_01550 1.3e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PGNNCGIA_01551 2.2e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGNNCGIA_01552 2.5e-103 wecD M Acetyltransferase (GNAT) domain
PGNNCGIA_01553 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGNNCGIA_01554 1.3e-157 GK ROK family
PGNNCGIA_01555 1.5e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
PGNNCGIA_01556 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
PGNNCGIA_01557 1.7e-204 potD P spermidine putrescine ABC transporter
PGNNCGIA_01558 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
PGNNCGIA_01559 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
PGNNCGIA_01560 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PGNNCGIA_01561 1.8e-167 murB 1.3.1.98 M cell wall formation
PGNNCGIA_01562 2.4e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGNNCGIA_01563 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGNNCGIA_01564 1.3e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PGNNCGIA_01565 5.9e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGNNCGIA_01566 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
PGNNCGIA_01567 0.0 ydaO E amino acid
PGNNCGIA_01568 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGNNCGIA_01569 1.5e-36 ylqC L Belongs to the UPF0109 family
PGNNCGIA_01570 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PGNNCGIA_01572 6.2e-201 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01573 7.6e-124 agrA KT phosphorelay signal transduction system
PGNNCGIA_01574 3.9e-163 O protein import
PGNNCGIA_01575 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PGNNCGIA_01576 2.2e-17 yjdB S Domain of unknown function (DUF4767)
PGNNCGIA_01577 1.8e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGNNCGIA_01579 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PGNNCGIA_01580 5.8e-72 S QueT transporter
PGNNCGIA_01582 3.5e-172 yfjR K regulation of single-species biofilm formation
PGNNCGIA_01584 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PGNNCGIA_01585 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGNNCGIA_01586 1.7e-85 ccl S cog cog4708
PGNNCGIA_01587 4.3e-156 rbn E Belongs to the UPF0761 family
PGNNCGIA_01588 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PGNNCGIA_01589 1.1e-231 ytoI K transcriptional regulator containing CBS domains
PGNNCGIA_01590 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PGNNCGIA_01591 9.1e-226 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGNNCGIA_01592 0.0 comEC S Competence protein ComEC
PGNNCGIA_01593 2.2e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PGNNCGIA_01594 1.3e-142 plsC 2.3.1.51 I Acyltransferase
PGNNCGIA_01595 2.1e-142 nodB3 G deacetylase
PGNNCGIA_01596 1.4e-125 yabB 2.1.1.223 L Methyltransferase
PGNNCGIA_01597 1.1e-40 yazA L endonuclease containing a URI domain
PGNNCGIA_01598 5.6e-27 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PGNNCGIA_01599 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PGNNCGIA_01600 1.8e-151 corA P CorA-like protein
PGNNCGIA_01601 2.5e-62 yjqA S Bacterial PH domain
PGNNCGIA_01602 1.7e-99 thiT S Thiamine transporter
PGNNCGIA_01603 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGNNCGIA_01604 1.8e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
PGNNCGIA_01605 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGNNCGIA_01609 1.7e-154 cjaA ET ABC transporter substrate-binding protein
PGNNCGIA_01610 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_01611 3e-106 P ABC transporter (Permease
PGNNCGIA_01612 3e-114 papP P ABC transporter (Permease
PGNNCGIA_01613 6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PGNNCGIA_01614 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PGNNCGIA_01615 0.0 copA 3.6.3.54 P P-type ATPase
PGNNCGIA_01616 5.2e-72 copY K negative regulation of transcription, DNA-templated
PGNNCGIA_01617 2.8e-173 EGP Major facilitator Superfamily
PGNNCGIA_01618 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PGNNCGIA_01619 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PGNNCGIA_01620 4.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PGNNCGIA_01621 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PGNNCGIA_01622 1.1e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGNNCGIA_01623 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PGNNCGIA_01624 5.3e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGNNCGIA_01625 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
PGNNCGIA_01626 7.5e-59
PGNNCGIA_01627 0.0 ctpE P E1-E2 ATPase
PGNNCGIA_01628 9e-47
PGNNCGIA_01629 1.5e-49
PGNNCGIA_01630 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGNNCGIA_01632 1.9e-124 V abc transporter atp-binding protein
PGNNCGIA_01633 0.0 V ABC transporter (Permease
PGNNCGIA_01634 3.1e-125 K transcriptional regulator, MerR family
PGNNCGIA_01635 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
PGNNCGIA_01636 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
PGNNCGIA_01637 2.8e-63 XK27_02560 S cog cog2151
PGNNCGIA_01638 1.5e-62
PGNNCGIA_01639 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PGNNCGIA_01640 2.1e-213 ytfP S Flavoprotein
PGNNCGIA_01642 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGNNCGIA_01643 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
PGNNCGIA_01644 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
PGNNCGIA_01645 2.2e-131 ecsA V abc transporter atp-binding protein
PGNNCGIA_01646 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PGNNCGIA_01649 1.6e-103
PGNNCGIA_01651 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PGNNCGIA_01652 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
PGNNCGIA_01653 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PGNNCGIA_01654 2.9e-196 ylbM S Belongs to the UPF0348 family
PGNNCGIA_01655 8.4e-139 yqeM Q Methyltransferase domain protein
PGNNCGIA_01656 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGNNCGIA_01657 7.8e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PGNNCGIA_01658 2.3e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGNNCGIA_01659 7.7e-49 yhbY J RNA-binding protein
PGNNCGIA_01660 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PGNNCGIA_01661 5.1e-98 yqeG S hydrolase of the HAD superfamily
PGNNCGIA_01662 8.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGNNCGIA_01663 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PGNNCGIA_01664 1.1e-60
PGNNCGIA_01665 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGNNCGIA_01666 1.5e-57
PGNNCGIA_01667 8.5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
PGNNCGIA_01668 2.2e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
PGNNCGIA_01669 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
PGNNCGIA_01670 7.2e-31 S PQ loop repeat
PGNNCGIA_01671 1.2e-36 S Sulfite exporter TauE/SafE
PGNNCGIA_01672 2.7e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PGNNCGIA_01674 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGNNCGIA_01675 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGNNCGIA_01676 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGNNCGIA_01677 3.1e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGNNCGIA_01678 1.6e-188 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGNNCGIA_01679 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
PGNNCGIA_01680 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PGNNCGIA_01681 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PGNNCGIA_01682 8.3e-99 pncA Q isochorismatase
PGNNCGIA_01683 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PGNNCGIA_01684 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PGNNCGIA_01685 9e-75 XK27_03180 T universal stress protein
PGNNCGIA_01687 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGNNCGIA_01688 6.2e-09 MU outer membrane autotransporter barrel domain protein
PGNNCGIA_01689 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PGNNCGIA_01690 8.6e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PGNNCGIA_01691 0.0 yjcE P NhaP-type Na H and K H antiporters
PGNNCGIA_01693 4.2e-95 ytqB J (SAM)-dependent
PGNNCGIA_01694 5.4e-183 yhcC S radical SAM protein
PGNNCGIA_01695 3.2e-187 ylbL T Belongs to the peptidase S16 family
PGNNCGIA_01696 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGNNCGIA_01697 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
PGNNCGIA_01698 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGNNCGIA_01699 5e-10 S Protein of unknown function (DUF4059)
PGNNCGIA_01700 9.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
PGNNCGIA_01701 2.3e-162 yxeN P ABC transporter (Permease
PGNNCGIA_01702 3.3e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGNNCGIA_01703 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGNNCGIA_01704 6.1e-35
PGNNCGIA_01705 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGNNCGIA_01706 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PGNNCGIA_01707 2.7e-143 cah 4.2.1.1 P carbonic anhydrase
PGNNCGIA_01708 5.3e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGNNCGIA_01710 6.9e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PGNNCGIA_01711 3.2e-141 cppA E CppA N-terminal
PGNNCGIA_01712 4.5e-107 V CAAX protease self-immunity
PGNNCGIA_01713 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PGNNCGIA_01714 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PGNNCGIA_01715 6.7e-07
PGNNCGIA_01717 3.7e-45 spiA K sequence-specific DNA binding
PGNNCGIA_01720 1.8e-133 agrA KT LytTr DNA-binding domain
PGNNCGIA_01721 1.9e-218 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PGNNCGIA_01726 1.5e-25 S Bacteriocin class II with double-glycine leader peptide
PGNNCGIA_01727 0.0 mdlB V abc transporter atp-binding protein
PGNNCGIA_01728 0.0 mdlA V abc transporter atp-binding protein
PGNNCGIA_01731 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
PGNNCGIA_01732 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PGNNCGIA_01733 4.8e-62 yutD J protein conserved in bacteria
PGNNCGIA_01734 8.5e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PGNNCGIA_01737 2.3e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGNNCGIA_01738 8.2e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGNNCGIA_01739 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PGNNCGIA_01740 2.4e-45 ftsL D cell division protein FtsL
PGNNCGIA_01741 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGNNCGIA_01742 3.9e-94
PGNNCGIA_01744 3.7e-48 yhaI J Protein of unknown function (DUF805)
PGNNCGIA_01745 1.3e-61 yhaI J Protein of unknown function (DUF805)
PGNNCGIA_01746 4.6e-33 yhaI J Protein of unknown function (DUF805)
PGNNCGIA_01747 6.7e-58 yhaI J Membrane
PGNNCGIA_01748 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGNNCGIA_01749 1.8e-139 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGNNCGIA_01750 7.5e-286 XK27_00765
PGNNCGIA_01751 8.1e-134 ecsA_2 V abc transporter atp-binding protein
PGNNCGIA_01752 4e-125 S Protein of unknown function (DUF554)
PGNNCGIA_01753 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PGNNCGIA_01754 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PGNNCGIA_01755 8.6e-246 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01756 8.5e-235 dcuS 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01757 5.2e-14
PGNNCGIA_01760 5.8e-146 V Psort location CytoplasmicMembrane, score
PGNNCGIA_01762 8.6e-298 O MreB/Mbl protein
PGNNCGIA_01763 1.2e-46 mccF V LD-carboxypeptidase
PGNNCGIA_01764 3.5e-118 liaI S membrane
PGNNCGIA_01765 1.2e-74 XK27_02470 K LytTr DNA-binding domain protein
PGNNCGIA_01766 8.7e-304 KT response to antibiotic
PGNNCGIA_01767 2.9e-93 yebC M Membrane
PGNNCGIA_01768 2.4e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
PGNNCGIA_01769 7.1e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PGNNCGIA_01771 2.9e-31 yozG K Transcriptional regulator
PGNNCGIA_01775 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGNNCGIA_01776 5.2e-201 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGNNCGIA_01777 5.8e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGNNCGIA_01778 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PGNNCGIA_01779 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PGNNCGIA_01780 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGNNCGIA_01782 1.5e-79 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGNNCGIA_01783 1.2e-91 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGNNCGIA_01784 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PGNNCGIA_01785 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PGNNCGIA_01786 1.7e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
PGNNCGIA_01787 3.7e-179 scrR K purine nucleotide biosynthetic process
PGNNCGIA_01788 4e-72 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGNNCGIA_01789 1.7e-61 yqhY S protein conserved in bacteria
PGNNCGIA_01790 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGNNCGIA_01791 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
PGNNCGIA_01792 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PGNNCGIA_01793 2.8e-32 blpT
PGNNCGIA_01797 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PGNNCGIA_01798 1e-168 corA P COG0598 Mg2 and Co2 transporters
PGNNCGIA_01799 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
PGNNCGIA_01801 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGNNCGIA_01802 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGNNCGIA_01803 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PGNNCGIA_01804 3.8e-43 XK27_05745
PGNNCGIA_01805 6.8e-220 mutY L A G-specific adenine glycosylase
PGNNCGIA_01807 1.5e-35
PGNNCGIA_01809 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGNNCGIA_01810 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGNNCGIA_01811 6.1e-94 cvpA S toxin biosynthetic process
PGNNCGIA_01812 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PGNNCGIA_01813 5e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGNNCGIA_01814 7.4e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PGNNCGIA_01815 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGNNCGIA_01816 1.3e-46 azlD S branched-chain amino acid
PGNNCGIA_01817 9.7e-113 azlC E AzlC protein
PGNNCGIA_01818 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGNNCGIA_01819 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PGNNCGIA_01820 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PGNNCGIA_01821 1.5e-33 ykzG S Belongs to the UPF0356 family
PGNNCGIA_01822 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGNNCGIA_01823 3e-40 L COG1943 Transposase and inactivated derivatives
PGNNCGIA_01824 9.5e-115 pscB M CHAP domain protein
PGNNCGIA_01825 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
PGNNCGIA_01826 2.5e-62 glnR K Transcriptional regulator
PGNNCGIA_01827 6.7e-87 S Fusaric acid resistance protein-like
PGNNCGIA_01828 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PGNNCGIA_01829 1.9e-186 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGNNCGIA_01830 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGNNCGIA_01831 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGNNCGIA_01832 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGNNCGIA_01833 4e-142 purR 2.4.2.7 F operon repressor
PGNNCGIA_01834 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
PGNNCGIA_01835 3.2e-170 rmuC S RmuC domain protein
PGNNCGIA_01836 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
PGNNCGIA_01837 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PGNNCGIA_01838 3.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGNNCGIA_01840 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGNNCGIA_01841 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGNNCGIA_01842 3.6e-143 tatD L Hydrolase, tatd
PGNNCGIA_01843 1.2e-73 yccU S CoA-binding protein
PGNNCGIA_01844 2.4e-50 trxA O Belongs to the thioredoxin family
PGNNCGIA_01845 1.7e-142 S Macro domain protein
PGNNCGIA_01846 1.8e-61 L thioesterase
PGNNCGIA_01847 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
PGNNCGIA_01850 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PGNNCGIA_01851 3.4e-14 rpmH J Ribosomal protein L34
PGNNCGIA_01852 4.5e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PGNNCGIA_01853 2.1e-103 K Transcriptional regulator
PGNNCGIA_01854 1.2e-151 jag S RNA-binding protein
PGNNCGIA_01855 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGNNCGIA_01856 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGNNCGIA_01857 7.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
PGNNCGIA_01858 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGNNCGIA_01859 7.2e-130 fasA KT Response regulator of the LytR AlgR family
PGNNCGIA_01860 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01861 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01862 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
PGNNCGIA_01863 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PGNNCGIA_01864 6.7e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGNNCGIA_01865 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PGNNCGIA_01866 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGNNCGIA_01867 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGNNCGIA_01868 1.2e-50 S Protein of unknown function (DUF3397)
PGNNCGIA_01869 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PGNNCGIA_01870 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
PGNNCGIA_01871 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGNNCGIA_01872 8.7e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PGNNCGIA_01873 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PGNNCGIA_01874 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
PGNNCGIA_01875 2.1e-230 XK27_09615 C reductase
PGNNCGIA_01876 2.4e-139 fnt P Formate nitrite transporter
PGNNCGIA_01877 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
PGNNCGIA_01878 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PGNNCGIA_01879 6.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PGNNCGIA_01880 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PGNNCGIA_01881 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGNNCGIA_01882 1.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGNNCGIA_01883 1e-56 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGNNCGIA_01884 1.6e-137 S HAD hydrolase, family IA, variant
PGNNCGIA_01885 8.3e-159 rrmA 2.1.1.187 Q methyltransferase
PGNNCGIA_01889 3.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGNNCGIA_01890 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGNNCGIA_01891 8.3e-37 yeeD O sulfur carrier activity
PGNNCGIA_01892 2e-186 yeeE S Sulphur transport
PGNNCGIA_01893 2.5e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGNNCGIA_01894 2.6e-09 S NTF2 fold immunity protein
PGNNCGIA_01895 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PGNNCGIA_01896 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
PGNNCGIA_01897 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PGNNCGIA_01898 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGNNCGIA_01899 2.2e-93 S CAAX amino terminal protease family protein
PGNNCGIA_01901 1.4e-108 V CAAX protease self-immunity
PGNNCGIA_01902 8.8e-27 lanR K sequence-specific DNA binding
PGNNCGIA_01903 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGNNCGIA_01904 3.8e-176 ytxK 2.1.1.72 L DNA methylase
PGNNCGIA_01905 1.5e-12 comGF U Putative Competence protein ComGF
PGNNCGIA_01906 9.9e-71 comGF U Competence protein ComGF
PGNNCGIA_01907 5.3e-15 NU Type II secretory pathway pseudopilin
PGNNCGIA_01908 8.4e-70 cglD NU Competence protein
PGNNCGIA_01909 2.2e-43 comGC U Required for transformation and DNA binding
PGNNCGIA_01910 7.4e-144 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGNNCGIA_01911 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGNNCGIA_01912 3.8e-68 S cog cog4699
PGNNCGIA_01913 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGNNCGIA_01914 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGNNCGIA_01915 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGNNCGIA_01916 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGNNCGIA_01917 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGNNCGIA_01918 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
PGNNCGIA_01919 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PGNNCGIA_01920 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PGNNCGIA_01921 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
PGNNCGIA_01922 1.4e-57 asp S cog cog1302
PGNNCGIA_01923 4.6e-225 norN V Mate efflux family protein
PGNNCGIA_01924 2.1e-277 thrC 4.2.3.1 E Threonine synthase
PGNNCGIA_01927 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PGNNCGIA_01928 0.0 pepO 3.4.24.71 O Peptidase family M13
PGNNCGIA_01929 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PGNNCGIA_01930 7.7e-112 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PGNNCGIA_01931 7.4e-166 treB 2.7.1.201 G pts system
PGNNCGIA_01932 6e-126 treR K trehalose operon
PGNNCGIA_01933 4.3e-95 ywlG S Belongs to the UPF0340 family
PGNNCGIA_01936 3.2e-84 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
PGNNCGIA_01937 2.9e-51 V ABC-2 family transporter protein
PGNNCGIA_01939 5.1e-102 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PGNNCGIA_01940 4.2e-84 KT Transcriptional regulatory protein, C terminal
PGNNCGIA_01941 8.2e-131 O Subtilase family
PGNNCGIA_01942 7.1e-37
PGNNCGIA_01943 4.2e-87 spaC2 V Lanthionine synthetase C-like protein
PGNNCGIA_01944 1.3e-175 spaT V ATPases associated with a variety of cellular activities
PGNNCGIA_01945 1.3e-211 spaB S Lantibiotic dehydratase, C terminus
PGNNCGIA_01949 7.1e-19 L Transposase (IS116 IS110 IS902 family)
PGNNCGIA_01950 4.4e-105 K Peptidase S24-like protein
PGNNCGIA_01951 6.2e-133 E IrrE N-terminal-like domain
PGNNCGIA_01953 1.5e-45 K Helix-turn-helix XRE-family like proteins
PGNNCGIA_01955 1.7e-42
PGNNCGIA_01956 2.9e-73
PGNNCGIA_01957 6.6e-272 ydcQ D Ftsk spoiiie family protein
PGNNCGIA_01958 5.4e-223 K Replication initiation factor
PGNNCGIA_01959 4.3e-33
PGNNCGIA_01960 4.3e-87
PGNNCGIA_01961 1.6e-161 S Conjugative transposon protein TcpC
PGNNCGIA_01962 3.2e-33
PGNNCGIA_01963 4.6e-70 S TcpE family
PGNNCGIA_01964 0.0 yddE S AAA-like domain
PGNNCGIA_01965 4.2e-259
PGNNCGIA_01966 4.4e-30
PGNNCGIA_01967 1.5e-171 isp2 S pathogenesis
PGNNCGIA_01968 3.4e-153
PGNNCGIA_01969 6.8e-16
PGNNCGIA_01970 3.4e-186 L Phage integrase family
PGNNCGIA_01971 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PGNNCGIA_01973 3.9e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
PGNNCGIA_01974 4.4e-62 rplQ J ribosomal protein l17
PGNNCGIA_01975 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGNNCGIA_01976 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGNNCGIA_01977 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGNNCGIA_01978 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PGNNCGIA_01979 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGNNCGIA_01980 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGNNCGIA_01981 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGNNCGIA_01982 5.7e-58 rplO J binds to the 23S rRNA
PGNNCGIA_01983 1.9e-23 rpmD J ribosomal protein l30
PGNNCGIA_01984 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGNNCGIA_01985 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGNNCGIA_01986 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGNNCGIA_01987 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGNNCGIA_01988 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGNNCGIA_01989 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGNNCGIA_01990 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGNNCGIA_01991 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGNNCGIA_01992 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGNNCGIA_01993 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PGNNCGIA_01994 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGNNCGIA_01995 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGNNCGIA_01996 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGNNCGIA_01997 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGNNCGIA_01998 1.2e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGNNCGIA_01999 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGNNCGIA_02000 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PGNNCGIA_02001 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGNNCGIA_02002 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PGNNCGIA_02003 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGNNCGIA_02004 0.0 XK27_09800 I Acyltransferase
PGNNCGIA_02005 9.7e-36 XK27_09805 S MORN repeat protein
PGNNCGIA_02006 3.2e-77 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGNNCGIA_02007 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGNNCGIA_02008 3.8e-90 adk 2.7.4.3 F topology modulation protein
PGNNCGIA_02010 7e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PGNNCGIA_02011 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PGNNCGIA_02012 6.3e-44 yrzL S Belongs to the UPF0297 family
PGNNCGIA_02013 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGNNCGIA_02014 7.2e-44 yrzB S Belongs to the UPF0473 family
PGNNCGIA_02015 1.1e-290 ccs S the current gene model (or a revised gene model) may contain a frame shift
PGNNCGIA_02016 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PGNNCGIA_02017 1.7e-13
PGNNCGIA_02018 1.6e-88 XK27_10930 K acetyltransferase
PGNNCGIA_02019 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGNNCGIA_02020 3.6e-123 yaaA S Belongs to the UPF0246 family
PGNNCGIA_02021 9.3e-167 XK27_01785 S cog cog1284
PGNNCGIA_02022 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PGNNCGIA_02024 1.6e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
PGNNCGIA_02025 6.1e-236 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PGNNCGIA_02026 1.5e-219 metE 2.1.1.14 E Methionine synthase
PGNNCGIA_02027 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PGNNCGIA_02028 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGNNCGIA_02029 9.2e-217 KLT Protein tyrosine kinase
PGNNCGIA_02030 3.4e-94 tnp* L An automated process has identified a potential problem with this gene model
PGNNCGIA_02031 8.3e-131 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PGNNCGIA_02032 6.5e-29 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PGNNCGIA_02033 8.4e-60 fruR K transcriptional
PGNNCGIA_02034 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PGNNCGIA_02035 7.6e-162 T Diguanylate cyclase
PGNNCGIA_02037 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PGNNCGIA_02038 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
PGNNCGIA_02039 0.0
PGNNCGIA_02044 7e-115 nudL L hydrolase
PGNNCGIA_02045 6.3e-54 K transcriptional regulator, PadR family
PGNNCGIA_02046 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
PGNNCGIA_02047 4.4e-107 S Putative adhesin
PGNNCGIA_02048 7.3e-160 XK27_06930 V domain protein
PGNNCGIA_02049 9.3e-95 XK27_06935 K transcriptional regulator
PGNNCGIA_02050 5.4e-54 ypaA M Membrane
PGNNCGIA_02051 1.9e-10
PGNNCGIA_02052 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGNNCGIA_02053 1.8e-47 veg S Biofilm formation stimulator VEG
PGNNCGIA_02054 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PGNNCGIA_02055 2.2e-73 rplI J binds to the 23S rRNA
PGNNCGIA_02056 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PGNNCGIA_02057 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGNNCGIA_02058 2.4e-99 yvbG U UPF0056 membrane protein
PGNNCGIA_02059 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGNNCGIA_02060 2.4e-311 S Bacterial membrane protein, YfhO
PGNNCGIA_02061 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
PGNNCGIA_02062 1e-70 lytE M LysM domain protein
PGNNCGIA_02063 5.3e-131 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGNNCGIA_02064 4.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGNNCGIA_02065 5.3e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGNNCGIA_02066 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGNNCGIA_02067 2e-131 S sequence-specific DNA binding
PGNNCGIA_02068 1e-237 ymfH S Peptidase M16
PGNNCGIA_02069 1.1e-231 ymfF S Peptidase M16
PGNNCGIA_02070 3.7e-58 yaaA S S4 domain protein YaaA
PGNNCGIA_02071 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGNNCGIA_02072 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PGNNCGIA_02073 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PGNNCGIA_02074 7.8e-152 yvjA S membrane
PGNNCGIA_02075 1.1e-305 ybiT S abc transporter atp-binding protein
PGNNCGIA_02076 0.0 XK27_10405 S Bacterial membrane protein YfhO
PGNNCGIA_02078 4e-119 yoaK S Protein of unknown function (DUF1275)
PGNNCGIA_02079 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGNNCGIA_02080 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PGNNCGIA_02081 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)