ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPDMPPNO_00001 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPDMPPNO_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPDMPPNO_00003 1.1e-29 yyzM S Protein conserved in bacteria
NPDMPPNO_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPDMPPNO_00005 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPDMPPNO_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPDMPPNO_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NPDMPPNO_00008 3e-60 divIC D Septum formation initiator
NPDMPPNO_00010 1.3e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NPDMPPNO_00011 1.2e-233 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPDMPPNO_00012 2.2e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPDMPPNO_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPDMPPNO_00026 2.6e-10
NPDMPPNO_00032 3.2e-110 mreC M Involved in formation and maintenance of cell shape
NPDMPPNO_00033 3e-82 mreD M rod shape-determining protein MreD
NPDMPPNO_00034 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
NPDMPPNO_00035 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPDMPPNO_00036 1.1e-217 araT 2.6.1.1 E Aminotransferase
NPDMPPNO_00037 8e-140 recO L Involved in DNA repair and RecF pathway recombination
NPDMPPNO_00038 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPDMPPNO_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPDMPPNO_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPDMPPNO_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPDMPPNO_00042 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPDMPPNO_00043 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPDMPPNO_00044 1.2e-97 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPDMPPNO_00045 8.6e-30
NPDMPPNO_00046 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPDMPPNO_00049 5e-157 2.7.7.49 L reverse transcriptase
NPDMPPNO_00050 2e-157 S CHAP domain
NPDMPPNO_00052 2.5e-239 purD 6.3.4.13 F Belongs to the GARS family
NPDMPPNO_00053 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPDMPPNO_00054 8.7e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPDMPPNO_00055 1.4e-173 1.1.1.169 H Ketopantoate reductase
NPDMPPNO_00056 1.9e-33
NPDMPPNO_00057 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPDMPPNO_00058 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NPDMPPNO_00059 6.9e-69 argR K Regulates arginine biosynthesis genes
NPDMPPNO_00060 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NPDMPPNO_00061 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPDMPPNO_00062 1.5e-77 S Protein of unknown function (DUF3021)
NPDMPPNO_00063 1.1e-69 K LytTr DNA-binding domain
NPDMPPNO_00065 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPDMPPNO_00067 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPDMPPNO_00068 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NPDMPPNO_00069 8.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
NPDMPPNO_00070 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPDMPPNO_00071 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NPDMPPNO_00077 2.6e-10
NPDMPPNO_00080 1.9e-07
NPDMPPNO_00085 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPDMPPNO_00086 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NPDMPPNO_00087 1.2e-35 XK27_02060 S Transglycosylase associated protein
NPDMPPNO_00088 3.9e-72 badR K Transcriptional regulator, marr family
NPDMPPNO_00089 3.2e-95 S reductase
NPDMPPNO_00091 1.3e-287 ahpF O alkyl hydroperoxide reductase
NPDMPPNO_00092 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
NPDMPPNO_00093 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
NPDMPPNO_00094 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPDMPPNO_00095 1.6e-82 S Putative small multi-drug export protein
NPDMPPNO_00096 1.8e-75 ctsR K Belongs to the CtsR family
NPDMPPNO_00097 0.0 clpC O Belongs to the ClpA ClpB family
NPDMPPNO_00098 3.5e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPDMPPNO_00099 2.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPDMPPNO_00100 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NPDMPPNO_00101 4.7e-140 S SseB protein N-terminal domain
NPDMPPNO_00102 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
NPDMPPNO_00104 6.9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPDMPPNO_00105 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPDMPPNO_00107 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPDMPPNO_00108 1.7e-90 yacP S RNA-binding protein containing a PIN domain
NPDMPPNO_00109 5.9e-152 degV S DegV family
NPDMPPNO_00111 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPDMPPNO_00112 2.8e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NPDMPPNO_00113 1.8e-19
NPDMPPNO_00114 4.5e-29 K Helix-turn-helix domain
NPDMPPNO_00116 2e-149 srtB 3.4.22.70 S Sortase family
NPDMPPNO_00117 1.1e-233 capA M Bacterial capsule synthesis protein
NPDMPPNO_00118 8e-39 gcvR T UPF0237 protein
NPDMPPNO_00119 2.8e-241 XK27_08635 S UPF0210 protein
NPDMPPNO_00120 2.3e-130 ais G Phosphoglycerate mutase
NPDMPPNO_00121 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NPDMPPNO_00122 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
NPDMPPNO_00123 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPDMPPNO_00124 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPDMPPNO_00125 2.3e-302 dnaK O Heat shock 70 kDa protein
NPDMPPNO_00126 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPDMPPNO_00127 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPDMPPNO_00128 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NPDMPPNO_00129 7.4e-80 hmpT S cog cog4720
NPDMPPNO_00142 1.9e-86 sigH K DNA-templated transcription, initiation
NPDMPPNO_00143 5.8e-138 ykuT M mechanosensitive ion channel
NPDMPPNO_00144 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPDMPPNO_00145 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPDMPPNO_00146 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPDMPPNO_00147 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
NPDMPPNO_00148 2.4e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NPDMPPNO_00149 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
NPDMPPNO_00150 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPDMPPNO_00151 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPDMPPNO_00152 5.9e-82 nrdI F Belongs to the NrdI family
NPDMPPNO_00153 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPDMPPNO_00154 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPDMPPNO_00155 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NPDMPPNO_00156 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPDMPPNO_00157 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPDMPPNO_00158 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NPDMPPNO_00159 7.6e-195 yhjX P Major Facilitator
NPDMPPNO_00160 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPDMPPNO_00161 1.8e-83 V VanZ like family
NPDMPPNO_00162 2.1e-181 D nuclear chromosome segregation
NPDMPPNO_00163 2.9e-123 glnQ E abc transporter atp-binding protein
NPDMPPNO_00164 1.3e-271 glnP P ABC transporter
NPDMPPNO_00165 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPDMPPNO_00166 4.8e-18 S Protein of unknown function (DUF3021)
NPDMPPNO_00167 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPDMPPNO_00168 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
NPDMPPNO_00169 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NPDMPPNO_00170 1.2e-233 sufD O assembly protein SufD
NPDMPPNO_00171 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPDMPPNO_00172 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
NPDMPPNO_00173 2.9e-273 sufB O assembly protein SufB
NPDMPPNO_00174 4.7e-26
NPDMPPNO_00175 1e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPDMPPNO_00176 6.2e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPDMPPNO_00177 1.6e-71 adcR K transcriptional
NPDMPPNO_00178 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
NPDMPPNO_00179 5.1e-129 adcB P ABC transporter (Permease
NPDMPPNO_00180 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NPDMPPNO_00181 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NPDMPPNO_00182 5.2e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NPDMPPNO_00183 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
NPDMPPNO_00184 6.2e-149 Z012_04635 K sequence-specific DNA binding
NPDMPPNO_00185 3.8e-282 V ABC transporter
NPDMPPNO_00186 6.1e-126 yeeN K transcriptional regulatory protein
NPDMPPNO_00187 1.7e-46 yajC U protein transport
NPDMPPNO_00188 9.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPDMPPNO_00189 2.8e-132 cdsA 2.7.7.41 S Belongs to the CDS family
NPDMPPNO_00190 2.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPDMPPNO_00191 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPDMPPNO_00192 0.0 WQ51_06230 S ABC transporter
NPDMPPNO_00193 4e-142 cmpC S abc transporter atp-binding protein
NPDMPPNO_00194 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPDMPPNO_00195 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPDMPPNO_00197 5.5e-44
NPDMPPNO_00198 1.7e-54 S TM2 domain
NPDMPPNO_00199 2.6e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPDMPPNO_00200 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPDMPPNO_00201 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPDMPPNO_00202 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
NPDMPPNO_00203 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NPDMPPNO_00204 4.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NPDMPPNO_00205 5.6e-144 cof S Sucrose-6F-phosphate phosphohydrolase
NPDMPPNO_00206 6.5e-134 glcR K transcriptional regulator (DeoR family)
NPDMPPNO_00207 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPDMPPNO_00208 5.5e-72 K helix_turn_helix multiple antibiotic resistance protein
NPDMPPNO_00209 2.8e-224 S COG1073 Hydrolases of the alpha beta superfamily
NPDMPPNO_00210 7.5e-36 yjdF S Protein of unknown function (DUF2992)
NPDMPPNO_00211 2.2e-45 3.2.2.21 S YCII-related domain
NPDMPPNO_00212 1.5e-52 K regulation of RNA biosynthetic process
NPDMPPNO_00213 9.2e-153 cylA V abc transporter atp-binding protein
NPDMPPNO_00214 4.6e-133 cylB V ABC-2 type transporter
NPDMPPNO_00215 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
NPDMPPNO_00216 2.3e-32 S Protein of unknown function (DUF3021)
NPDMPPNO_00217 1.3e-123 mta K Transcriptional
NPDMPPNO_00218 2.5e-121 yhcA V abc transporter atp-binding protein
NPDMPPNO_00219 6.7e-216 macB_2 V FtsX-like permease family
NPDMPPNO_00220 8.4e-276 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPDMPPNO_00221 9e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPDMPPNO_00222 1.3e-73 yhaI S Protein of unknown function (DUF805)
NPDMPPNO_00223 1.7e-254 pepC 3.4.22.40 E aminopeptidase
NPDMPPNO_00224 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPDMPPNO_00225 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPDMPPNO_00226 9.8e-94 ypsA S Belongs to the UPF0398 family
NPDMPPNO_00227 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPDMPPNO_00228 7.4e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPDMPPNO_00229 3.3e-278 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NPDMPPNO_00230 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NPDMPPNO_00231 4.8e-22
NPDMPPNO_00232 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPDMPPNO_00233 1.2e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
NPDMPPNO_00234 1.2e-288 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPDMPPNO_00235 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPDMPPNO_00236 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPDMPPNO_00237 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPDMPPNO_00238 7.9e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPDMPPNO_00239 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NPDMPPNO_00240 2.2e-101 ybhL S Belongs to the BI1 family
NPDMPPNO_00241 2.4e-12 ycdA S Domain of unknown function (DUF4352)
NPDMPPNO_00242 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPDMPPNO_00243 1.8e-90 K transcriptional regulator
NPDMPPNO_00244 1.6e-36 yneF S UPF0154 protein
NPDMPPNO_00245 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPDMPPNO_00246 6.6e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPDMPPNO_00247 3.9e-98 XK27_09740 S Phosphoesterase
NPDMPPNO_00248 8.3e-87 ykuL S CBS domain
NPDMPPNO_00249 2.5e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NPDMPPNO_00250 1.8e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPDMPPNO_00251 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPDMPPNO_00252 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPDMPPNO_00253 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
NPDMPPNO_00254 4.9e-260 trkH P Cation transport protein
NPDMPPNO_00255 1e-246 trkA P Potassium transporter peripheral membrane component
NPDMPPNO_00256 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPDMPPNO_00257 6e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPDMPPNO_00258 2.7e-109 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NPDMPPNO_00259 7.3e-153 K sequence-specific DNA binding
NPDMPPNO_00260 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPDMPPNO_00261 1.3e-54 yhaI L Membrane
NPDMPPNO_00262 1.9e-245 S Domain of unknown function (DUF4173)
NPDMPPNO_00263 6.8e-95 ureI S AmiS/UreI family transporter
NPDMPPNO_00264 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NPDMPPNO_00265 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NPDMPPNO_00266 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPDMPPNO_00267 6.6e-78 ureE O enzyme active site formation
NPDMPPNO_00268 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NPDMPPNO_00269 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NPDMPPNO_00270 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NPDMPPNO_00271 3.9e-176 cbiM P biosynthesis protein CbiM
NPDMPPNO_00272 1.1e-136 P cobalt transport protein
NPDMPPNO_00273 6.3e-131 cbiO P ABC transporter
NPDMPPNO_00274 1.3e-143 ET amino acid transport
NPDMPPNO_00275 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
NPDMPPNO_00276 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NPDMPPNO_00277 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPDMPPNO_00278 1.2e-99 metI P ABC transporter (Permease
NPDMPPNO_00279 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NPDMPPNO_00280 1.4e-119 ktrA P COG0569 K transport systems, NAD-binding component
NPDMPPNO_00281 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
NPDMPPNO_00282 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NPDMPPNO_00283 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NPDMPPNO_00284 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDMPPNO_00285 4.6e-280 T PhoQ Sensor
NPDMPPNO_00286 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPDMPPNO_00287 8.8e-215 dnaB L Replication initiation and membrane attachment
NPDMPPNO_00288 2.9e-165 dnaI L Primosomal protein DnaI
NPDMPPNO_00289 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPDMPPNO_00290 2.8e-111
NPDMPPNO_00291 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPDMPPNO_00292 2.5e-62 manO S protein conserved in bacteria
NPDMPPNO_00293 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
NPDMPPNO_00294 4.5e-117 manM G pts system
NPDMPPNO_00295 4.9e-174 manL 2.7.1.191 G pts system
NPDMPPNO_00296 7.7e-67 manO S Protein conserved in bacteria
NPDMPPNO_00297 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
NPDMPPNO_00298 4.7e-135 manY G pts system
NPDMPPNO_00299 6.2e-169 manL 2.7.1.191 G pts system
NPDMPPNO_00300 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NPDMPPNO_00301 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NPDMPPNO_00302 1.6e-247 pbuO S permease
NPDMPPNO_00303 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NPDMPPNO_00304 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
NPDMPPNO_00305 9.8e-188 brpA K Transcriptional
NPDMPPNO_00306 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
NPDMPPNO_00307 4e-199 nusA K Participates in both transcription termination and antitermination
NPDMPPNO_00308 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NPDMPPNO_00309 1.4e-41 ylxQ J ribosomal protein
NPDMPPNO_00310 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPDMPPNO_00311 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPDMPPNO_00312 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
NPDMPPNO_00313 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NPDMPPNO_00314 8.1e-271 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPDMPPNO_00315 1.3e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NPDMPPNO_00316 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NPDMPPNO_00317 4.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
NPDMPPNO_00318 4.3e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NPDMPPNO_00319 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
NPDMPPNO_00320 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NPDMPPNO_00321 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPDMPPNO_00322 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPDMPPNO_00323 1.4e-72 ylbF S Belongs to the UPF0342 family
NPDMPPNO_00324 1.9e-46 ylbG S UPF0298 protein
NPDMPPNO_00325 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NPDMPPNO_00326 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
NPDMPPNO_00327 6.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
NPDMPPNO_00328 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NPDMPPNO_00329 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NPDMPPNO_00330 7.8e-112 acuB S CBS domain
NPDMPPNO_00331 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPDMPPNO_00332 4.5e-109 yvyE 3.4.13.9 S YigZ family
NPDMPPNO_00333 1.2e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NPDMPPNO_00334 2.6e-83 comFC K competence protein
NPDMPPNO_00335 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPDMPPNO_00343 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPDMPPNO_00344 2.3e-111 S Domain of unknown function (DUF1803)
NPDMPPNO_00345 7.8e-102 ygaC J Belongs to the UPF0374 family
NPDMPPNO_00346 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPDMPPNO_00347 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPDMPPNO_00348 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NPDMPPNO_00349 6.9e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPDMPPNO_00350 1.8e-113 S HAD hydrolase, family IA, variant 3
NPDMPPNO_00351 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NPDMPPNO_00352 2e-71 marR K Transcriptional regulator, MarR family
NPDMPPNO_00353 8.3e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPDMPPNO_00354 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPDMPPNO_00355 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NPDMPPNO_00356 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NPDMPPNO_00357 1.8e-125 IQ reductase
NPDMPPNO_00358 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPDMPPNO_00359 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPDMPPNO_00360 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPDMPPNO_00361 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NPDMPPNO_00362 8.6e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPDMPPNO_00363 2.6e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPDMPPNO_00364 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPDMPPNO_00365 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
NPDMPPNO_00366 4e-112 fruR K transcriptional
NPDMPPNO_00367 1.3e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPDMPPNO_00368 0.0 fruA 2.7.1.202 G phosphotransferase system
NPDMPPNO_00369 5.5e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NPDMPPNO_00370 9.4e-223 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPDMPPNO_00372 6.3e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NPDMPPNO_00373 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPDMPPNO_00374 1.9e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPDMPPNO_00375 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPDMPPNO_00376 3.5e-94 2.3.1.128 K acetyltransferase
NPDMPPNO_00377 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPDMPPNO_00378 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPDMPPNO_00379 3.6e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NPDMPPNO_00380 5e-63 WQ51_03320 S cog cog4835
NPDMPPNO_00381 2.1e-146 XK27_08360 S EDD domain protein, DegV family
NPDMPPNO_00382 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPDMPPNO_00383 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPDMPPNO_00384 0.0 yfmR S abc transporter atp-binding protein
NPDMPPNO_00385 1e-26 U response to pH
NPDMPPNO_00386 1.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NPDMPPNO_00387 1.3e-207 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NPDMPPNO_00388 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPDMPPNO_00389 3e-269 S Psort location CytoplasmicMembrane, score
NPDMPPNO_00390 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPDMPPNO_00391 7e-72 K DNA-binding transcription factor activity
NPDMPPNO_00392 8.6e-310 lmrA1 V abc transporter atp-binding protein
NPDMPPNO_00393 0.0 lmrA2 V abc transporter atp-binding protein
NPDMPPNO_00394 9.1e-110 K Acetyltransferase (GNAT) family
NPDMPPNO_00395 1.5e-109 2.7.6.5 S Region found in RelA / SpoT proteins
NPDMPPNO_00396 1.7e-114 T response regulator
NPDMPPNO_00397 8.8e-210 sptS 2.7.13.3 T Histidine kinase
NPDMPPNO_00398 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPDMPPNO_00399 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPDMPPNO_00400 1.3e-159 cvfB S Protein conserved in bacteria
NPDMPPNO_00401 3.7e-34 yozE S Belongs to the UPF0346 family
NPDMPPNO_00402 6.7e-130 sip M LysM domain protein
NPDMPPNO_00403 4.4e-189 phoH T phosphate starvation-inducible protein PhoH
NPDMPPNO_00407 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPDMPPNO_00408 1.5e-160 S reductase
NPDMPPNO_00409 1.8e-167 K transcriptional regulator (lysR family)
NPDMPPNO_00410 5.5e-106 S CAAX amino terminal protease family protein
NPDMPPNO_00411 5.6e-259 S Glucan-binding protein C
NPDMPPNO_00412 1e-173 coiA 3.6.4.12 S Competence protein
NPDMPPNO_00413 0.0 pepF E oligoendopeptidase F
NPDMPPNO_00414 9.1e-215 oxlT P COG0477 Permeases of the major facilitator superfamily
NPDMPPNO_00415 1.4e-119 yrrM 2.1.1.104 S O-Methyltransferase
NPDMPPNO_00416 3.6e-165 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NPDMPPNO_00417 8.7e-84 yxjI S LURP-one-related
NPDMPPNO_00418 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPDMPPNO_00419 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NPDMPPNO_00420 2.4e-133 agrA KT phosphorelay signal transduction system
NPDMPPNO_00421 4.1e-229 2.7.13.3 T GHKL domain
NPDMPPNO_00423 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
NPDMPPNO_00424 9.2e-136 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPDMPPNO_00425 5.7e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NPDMPPNO_00426 3.8e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPDMPPNO_00427 2.8e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPDMPPNO_00428 4.5e-124 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NPDMPPNO_00429 5.5e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NPDMPPNO_00430 8.8e-135 yxkH G deacetylase
NPDMPPNO_00431 3.4e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NPDMPPNO_00432 4.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPDMPPNO_00433 3.3e-150 rarD S Transporter
NPDMPPNO_00434 3.7e-15 T peptidase
NPDMPPNO_00435 3e-14 coiA 3.6.4.12 S Competence protein
NPDMPPNO_00436 1.3e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NPDMPPNO_00437 1.6e-42
NPDMPPNO_00438 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPDMPPNO_00439 3.5e-43 M1-386
NPDMPPNO_00440 2.8e-85
NPDMPPNO_00441 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPDMPPNO_00442 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NPDMPPNO_00443 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPDMPPNO_00444 1.3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPDMPPNO_00445 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPDMPPNO_00446 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPDMPPNO_00447 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPDMPPNO_00448 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPDMPPNO_00449 3.5e-217 ftsW D Belongs to the SEDS family
NPDMPPNO_00450 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPDMPPNO_00451 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPDMPPNO_00452 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPDMPPNO_00454 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPDMPPNO_00455 1.3e-159 holB 2.7.7.7 L dna polymerase iii
NPDMPPNO_00456 1.3e-132 yaaT S stage 0 sporulation protein
NPDMPPNO_00457 1.2e-54 yabA L Involved in initiation control of chromosome replication
NPDMPPNO_00458 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPDMPPNO_00459 4.3e-228 amt P Ammonium Transporter
NPDMPPNO_00460 9.5e-53 glnB K Belongs to the P(II) protein family
NPDMPPNO_00461 1.7e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
NPDMPPNO_00462 1.9e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NPDMPPNO_00463 9.9e-81 S Bacterial inner membrane protein
NPDMPPNO_00464 4.4e-112 3.4.17.14, 3.5.1.28 NU amidase activity
NPDMPPNO_00465 3.2e-292 nptA P COG1283 Na phosphate symporter
NPDMPPNO_00466 1e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPDMPPNO_00467 3.3e-220 S membrane
NPDMPPNO_00468 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPDMPPNO_00469 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPDMPPNO_00470 1.7e-38 ynzC S UPF0291 protein
NPDMPPNO_00471 6.7e-254 cycA E permease
NPDMPPNO_00472 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDMPPNO_00473 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NPDMPPNO_00474 1.2e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPDMPPNO_00478 3.4e-69 K Helix-turn-helix
NPDMPPNO_00480 4.7e-168 fhuR K transcriptional regulator (lysR family)
NPDMPPNO_00481 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPDMPPNO_00482 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPDMPPNO_00483 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPDMPPNO_00484 2.8e-222 pyrP F uracil Permease
NPDMPPNO_00485 6.5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPDMPPNO_00486 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NPDMPPNO_00487 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NPDMPPNO_00488 2.5e-122 2.1.1.223 S Putative SAM-dependent methyltransferase
NPDMPPNO_00489 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPDMPPNO_00490 3.4e-121 macB V ABC transporter, ATP-binding protein
NPDMPPNO_00491 1.4e-202 V permease protein
NPDMPPNO_00492 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPDMPPNO_00493 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPDMPPNO_00494 0.0 mdlB V abc transporter atp-binding protein
NPDMPPNO_00495 0.0 lmrA V abc transporter atp-binding protein
NPDMPPNO_00496 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPDMPPNO_00497 1.4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPDMPPNO_00498 3.8e-211 T signal transduction protein with a C-terminal ATPase domain
NPDMPPNO_00499 6.4e-128 rr02 KT response regulator
NPDMPPNO_00500 7.1e-164 V ABC transporter
NPDMPPNO_00501 1.3e-120 sagI S ABC-2 type transporter
NPDMPPNO_00503 2.6e-196 yceA S Belongs to the UPF0176 family
NPDMPPNO_00504 1e-27 XK27_00085 K Transcriptional
NPDMPPNO_00505 8.9e-20
NPDMPPNO_00506 5.9e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
NPDMPPNO_00507 2.3e-114 S VIT family
NPDMPPNO_00508 2.8e-140 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPDMPPNO_00509 3.2e-214 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NPDMPPNO_00510 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NPDMPPNO_00513 3e-142 E Alpha beta hydrolase
NPDMPPNO_00514 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NPDMPPNO_00515 7.1e-153 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NPDMPPNO_00516 9.6e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPDMPPNO_00517 8e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPDMPPNO_00518 8.6e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPDMPPNO_00519 6.4e-151 V ABC transporter, ATP-binding protein
NPDMPPNO_00520 2.9e-51 S ABC-2 family transporter protein
NPDMPPNO_00521 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPDMPPNO_00522 9.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPDMPPNO_00523 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NPDMPPNO_00524 1.1e-24
NPDMPPNO_00525 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPDMPPNO_00526 0.0 U protein secretion
NPDMPPNO_00527 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NPDMPPNO_00528 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NPDMPPNO_00529 6.8e-10
NPDMPPNO_00530 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPDMPPNO_00531 1.1e-159 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPDMPPNO_00532 1.6e-199 S Protein of unknown function (DUF3114)
NPDMPPNO_00533 4.1e-29 pspC KT PspC domain protein
NPDMPPNO_00534 5.2e-119 yqfA K protein, Hemolysin III
NPDMPPNO_00535 1.1e-77 K hmm pf08876
NPDMPPNO_00536 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NPDMPPNO_00537 1e-210 mvaS 2.3.3.10 I synthase
NPDMPPNO_00538 5.5e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPDMPPNO_00539 1.1e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPDMPPNO_00540 9.7e-22
NPDMPPNO_00541 9.8e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPDMPPNO_00542 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NPDMPPNO_00543 2e-239 mmuP E amino acid
NPDMPPNO_00544 2.4e-170 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NPDMPPNO_00545 2.2e-30 S Domain of unknown function (DUF1912)
NPDMPPNO_00546 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
NPDMPPNO_00547 2.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPDMPPNO_00548 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPDMPPNO_00550 1.4e-10
NPDMPPNO_00551 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPDMPPNO_00552 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
NPDMPPNO_00553 1.4e-15 S Protein of unknown function (DUF2969)
NPDMPPNO_00556 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
NPDMPPNO_00559 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
NPDMPPNO_00560 6.4e-117 M Pfam SNARE associated Golgi protein
NPDMPPNO_00561 1.6e-227 murN 2.3.2.16 V FemAB family
NPDMPPNO_00562 1.4e-173 S oxidoreductase
NPDMPPNO_00563 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
NPDMPPNO_00564 4.3e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NPDMPPNO_00565 0.0 clpE O Belongs to the ClpA ClpB family
NPDMPPNO_00566 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPDMPPNO_00567 1e-34 ykuJ S protein conserved in bacteria
NPDMPPNO_00568 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NPDMPPNO_00569 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_00570 4.5e-77 feoA P FeoA domain protein
NPDMPPNO_00571 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NPDMPPNO_00572 1.7e-08
NPDMPPNO_00573 1.5e-149 I Alpha/beta hydrolase family
NPDMPPNO_00574 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPDMPPNO_00575 8.6e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPDMPPNO_00576 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NPDMPPNO_00577 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPDMPPNO_00578 2.1e-146 licT K antiterminator
NPDMPPNO_00579 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPDMPPNO_00580 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NPDMPPNO_00581 4.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPDMPPNO_00582 1.6e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPDMPPNO_00583 1.8e-99 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPDMPPNO_00584 1.3e-221 mdtG EGP Major facilitator Superfamily
NPDMPPNO_00585 2e-33 secG U Preprotein translocase subunit SecG
NPDMPPNO_00586 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPDMPPNO_00587 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPDMPPNO_00588 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPDMPPNO_00589 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NPDMPPNO_00590 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NPDMPPNO_00591 2.4e-181 ccpA K Catabolite control protein A
NPDMPPNO_00592 3.6e-199 yyaQ S YjbR
NPDMPPNO_00593 6.4e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPDMPPNO_00594 3.3e-77 yueI S Protein of unknown function (DUF1694)
NPDMPPNO_00595 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPDMPPNO_00596 1.2e-25 WQ51_00785
NPDMPPNO_00597 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPDMPPNO_00598 1.7e-218 ywbD 2.1.1.191 J Methyltransferase
NPDMPPNO_00599 4.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPDMPPNO_00600 2.9e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPDMPPNO_00601 1.7e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPDMPPNO_00602 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPDMPPNO_00603 1e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NPDMPPNO_00604 4.2e-53 yheA S Belongs to the UPF0342 family
NPDMPPNO_00605 8e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NPDMPPNO_00606 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPDMPPNO_00607 2.2e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPDMPPNO_00608 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
NPDMPPNO_00609 1.5e-248 msrR K Transcriptional regulator
NPDMPPNO_00610 5.3e-154 ydiA P C4-dicarboxylate transporter malic acid transport
NPDMPPNO_00611 2.9e-201 I acyl-CoA dehydrogenase
NPDMPPNO_00612 2e-97 mip S hydroperoxide reductase activity
NPDMPPNO_00613 5.2e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPDMPPNO_00614 7.6e-36 S Pentapeptide repeat protein
NPDMPPNO_00615 6.3e-18
NPDMPPNO_00616 2e-38 K acetyltransferase
NPDMPPNO_00618 4.1e-12
NPDMPPNO_00620 1.4e-11 L Resolvase, N terminal domain
NPDMPPNO_00621 3e-113 K Psort location Cytoplasmic, score
NPDMPPNO_00622 1.3e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPDMPPNO_00623 3.7e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
NPDMPPNO_00624 1.1e-204 yeaN P transporter
NPDMPPNO_00625 8.4e-151 yitS S EDD domain protein, DegV family
NPDMPPNO_00626 2.3e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
NPDMPPNO_00627 5.4e-110 cutC P Participates in the control of copper homeostasis
NPDMPPNO_00629 7.1e-21 S Domain of unknown function (DUF4767)
NPDMPPNO_00630 3.2e-293 norB P Major facilitator superfamily
NPDMPPNO_00631 3.6e-94 tetR K transcriptional regulator
NPDMPPNO_00632 4e-153 S Domain of unknown function (DUF4300)
NPDMPPNO_00633 3.4e-127 V CAAX protease self-immunity
NPDMPPNO_00634 4.1e-155 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPDMPPNO_00635 7.1e-133 fecE 3.6.3.34 HP ABC transporter
NPDMPPNO_00636 1e-171 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPDMPPNO_00637 2.4e-119 ybbA S Putative esterase
NPDMPPNO_00638 2.4e-47
NPDMPPNO_00639 9.5e-122 V CAAX protease self-immunity
NPDMPPNO_00640 6.8e-11
NPDMPPNO_00641 2.5e-18 M Bacterial lipoprotein
NPDMPPNO_00642 1.5e-57 S Protein of unknown function (DUF1722)
NPDMPPNO_00643 8.8e-65 yqeB S Pyrimidine dimer DNA glycosylase
NPDMPPNO_00645 3.6e-50
NPDMPPNO_00646 7.5e-93 S CAAX protease self-immunity
NPDMPPNO_00647 2.7e-42 estA E GDSL-like Lipase/Acylhydrolase
NPDMPPNO_00648 3.5e-42 estA E GDSL-like Lipase/Acylhydrolase
NPDMPPNO_00649 3.8e-100
NPDMPPNO_00650 1.3e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
NPDMPPNO_00651 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NPDMPPNO_00652 1.9e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPDMPPNO_00653 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPDMPPNO_00654 1.3e-169 S CRISPR-associated protein Csn2 subfamily St
NPDMPPNO_00655 4.9e-148 ycgQ S TIGR03943 family
NPDMPPNO_00656 5.4e-156 XK27_03015 S permease
NPDMPPNO_00658 0.0 yhgF K Transcriptional accessory protein
NPDMPPNO_00659 3.9e-83 ydcK S Belongs to the SprT family
NPDMPPNO_00660 2.2e-41 pspC KT PspC domain
NPDMPPNO_00661 3.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPDMPPNO_00662 2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPDMPPNO_00663 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPDMPPNO_00664 1.9e-66 ytxH S General stress protein
NPDMPPNO_00666 8.9e-178 yegQ O Peptidase U32
NPDMPPNO_00667 7.5e-252 yegQ O Peptidase U32
NPDMPPNO_00668 3e-85 bioY S biotin synthase
NPDMPPNO_00670 1.1e-33 XK27_12190 S protein conserved in bacteria
NPDMPPNO_00671 3.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
NPDMPPNO_00672 8.7e-13
NPDMPPNO_00673 4.2e-10
NPDMPPNO_00674 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPDMPPNO_00675 3.7e-137 M LysM domain
NPDMPPNO_00676 8.4e-23
NPDMPPNO_00677 5.2e-175 S hydrolase
NPDMPPNO_00678 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NPDMPPNO_00679 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPDMPPNO_00680 1.9e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NPDMPPNO_00681 1.3e-26 P Hemerythrin HHE cation binding domain protein
NPDMPPNO_00682 2.1e-157 5.2.1.8 G hydrolase
NPDMPPNO_00683 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDMPPNO_00684 4e-212 MA20_36090 S Protein of unknown function (DUF2974)
NPDMPPNO_00685 7.9e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDMPPNO_00686 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
NPDMPPNO_00687 2.1e-280 hsdM 2.1.1.72 V type I restriction-modification system
NPDMPPNO_00688 3.4e-137 3.1.21.3 V Type I restriction modification DNA specificity domain
NPDMPPNO_00689 1.7e-135
NPDMPPNO_00690 9.1e-58
NPDMPPNO_00691 1.7e-54
NPDMPPNO_00692 6.7e-193 higA K Pfam:DUF955
NPDMPPNO_00693 2.9e-133 S double-stranded DNA endodeoxyribonuclease activity
NPDMPPNO_00694 0.0 2.4.1.21 GT5 M Right handed beta helix region
NPDMPPNO_00695 1.7e-174 spd F DNA RNA non-specific endonuclease
NPDMPPNO_00696 7.7e-92 lemA S LemA family
NPDMPPNO_00697 1.7e-133 htpX O Belongs to the peptidase M48B family
NPDMPPNO_00698 1.7e-119 sirR K iron dependent repressor
NPDMPPNO_00699 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
NPDMPPNO_00700 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
NPDMPPNO_00701 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
NPDMPPNO_00702 2.1e-74 S Psort location CytoplasmicMembrane, score
NPDMPPNO_00703 1.8e-63 S Domain of unknown function (DUF4430)
NPDMPPNO_00704 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPDMPPNO_00705 3.9e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
NPDMPPNO_00706 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NPDMPPNO_00707 5.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NPDMPPNO_00708 2.9e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NPDMPPNO_00709 1.1e-89 dps P Belongs to the Dps family
NPDMPPNO_00710 3.4e-79 perR P Belongs to the Fur family
NPDMPPNO_00711 7.1e-27 yqgQ S protein conserved in bacteria
NPDMPPNO_00712 2.7e-177 glk 2.7.1.2 G Glucokinase
NPDMPPNO_00713 0.0 typA T GTP-binding protein TypA
NPDMPPNO_00715 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPDMPPNO_00716 7.3e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPDMPPNO_00717 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPDMPPNO_00718 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPDMPPNO_00719 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPDMPPNO_00720 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPDMPPNO_00721 2.2e-86 sepF D cell septum assembly
NPDMPPNO_00722 5e-30 yggT D integral membrane protein
NPDMPPNO_00723 2.7e-143 ylmH S conserved protein, contains S4-like domain
NPDMPPNO_00724 8.4e-138 divIVA D Cell division initiation protein
NPDMPPNO_00725 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPDMPPNO_00726 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPDMPPNO_00727 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPDMPPNO_00728 2.2e-34 nrdH O Glutaredoxin
NPDMPPNO_00729 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NPDMPPNO_00730 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NPDMPPNO_00731 8.8e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
NPDMPPNO_00732 3e-38 ptsH G phosphocarrier protein Hpr
NPDMPPNO_00733 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPDMPPNO_00734 1.9e-223 L Transposase
NPDMPPNO_00735 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NPDMPPNO_00736 3.9e-161 XK27_05670 S Putative esterase
NPDMPPNO_00737 2.7e-153 XK27_05675 S Esterase
NPDMPPNO_00738 3.2e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
NPDMPPNO_00739 5.1e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
NPDMPPNO_00740 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NPDMPPNO_00741 0.0 uup S abc transporter atp-binding protein
NPDMPPNO_00742 2.7e-39 MA20_06245 S yiaA/B two helix domain
NPDMPPNO_00743 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
NPDMPPNO_00744 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPDMPPNO_00745 1.4e-147 cobQ S glutamine amidotransferase
NPDMPPNO_00746 6.4e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NPDMPPNO_00747 1.4e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPDMPPNO_00748 3.2e-162 ybbR S Protein conserved in bacteria
NPDMPPNO_00749 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPDMPPNO_00750 1.8e-66 gtrA S GtrA-like protein
NPDMPPNO_00751 4.8e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPDMPPNO_00752 9.6e-141 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPDMPPNO_00753 3.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
NPDMPPNO_00754 1.3e-193 yurR 1.4.5.1 E oxidoreductase
NPDMPPNO_00755 3.1e-256 S phospholipase Carboxylesterase
NPDMPPNO_00756 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPDMPPNO_00757 7e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPDMPPNO_00758 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPDMPPNO_00760 1.7e-30 KT response to antibiotic
NPDMPPNO_00761 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
NPDMPPNO_00762 2.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
NPDMPPNO_00763 1.5e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPDMPPNO_00764 8.7e-116 ylfI S tigr01906
NPDMPPNO_00765 2.3e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NPDMPPNO_00766 1.2e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NPDMPPNO_00767 3.7e-61 XK27_08085
NPDMPPNO_00768 7.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPDMPPNO_00769 4.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPDMPPNO_00770 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPDMPPNO_00771 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPDMPPNO_00772 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NPDMPPNO_00773 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPDMPPNO_00774 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPDMPPNO_00775 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPDMPPNO_00776 4.7e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NPDMPPNO_00777 3.4e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NPDMPPNO_00779 1.8e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
NPDMPPNO_00780 2.4e-144 P molecular chaperone
NPDMPPNO_00781 2.6e-95 S Carbohydrate-binding domain-containing protein Cthe_2159
NPDMPPNO_00782 3e-179 XK27_08075 M glycosyl transferase family 2
NPDMPPNO_00783 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_00784 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_00785 1.9e-178 L Transposase
NPDMPPNO_00786 8.1e-88 tag 3.2.2.20 L glycosylase
NPDMPPNO_00787 4.9e-41 S Sugar efflux transporter for intercellular exchange
NPDMPPNO_00788 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_00789 2.4e-235 rodA D Belongs to the SEDS family
NPDMPPNO_00790 1.9e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPDMPPNO_00791 6.9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NPDMPPNO_00792 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPDMPPNO_00793 5.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDMPPNO_00794 4.6e-126 Q Methyltransferase domain
NPDMPPNO_00795 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
NPDMPPNO_00796 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NPDMPPNO_00797 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPDMPPNO_00798 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NPDMPPNO_00799 1.3e-125 dnaD
NPDMPPNO_00800 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPDMPPNO_00802 1.5e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPDMPPNO_00803 1.8e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPDMPPNO_00804 1.9e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPDMPPNO_00805 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPDMPPNO_00806 8.3e-73 argR K Regulates arginine biosynthesis genes
NPDMPPNO_00807 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
NPDMPPNO_00808 4.4e-144 DegV S DegV family
NPDMPPNO_00809 2.3e-159 ypmR E COG2755 Lysophospholipase L1 and related esterases
NPDMPPNO_00810 1.8e-96 ypmS S Protein conserved in bacteria
NPDMPPNO_00811 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPDMPPNO_00813 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NPDMPPNO_00814 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPDMPPNO_00815 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPDMPPNO_00816 3.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NPDMPPNO_00817 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPDMPPNO_00818 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPDMPPNO_00819 0.0 dnaE 2.7.7.7 L DNA polymerase
NPDMPPNO_00820 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPDMPPNO_00821 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPDMPPNO_00822 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
NPDMPPNO_00823 1.7e-18 S Domain of unknown function (DUF4649)
NPDMPPNO_00824 6.2e-177 XK27_08835 S ABC transporter substrate binding protein
NPDMPPNO_00825 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NPDMPPNO_00826 8.9e-136 XK27_08845 S abc transporter atp-binding protein
NPDMPPNO_00827 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPDMPPNO_00828 8.6e-150 estA CE1 S Esterase
NPDMPPNO_00829 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
NPDMPPNO_00830 1.7e-18 XK27_08880
NPDMPPNO_00831 1e-75 fld C Flavodoxin
NPDMPPNO_00832 4.6e-280 clcA P Chloride transporter, ClC family
NPDMPPNO_00833 2.7e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NPDMPPNO_00834 3.3e-212 XK27_05110 P Chloride transporter ClC family
NPDMPPNO_00835 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPDMPPNO_00838 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NPDMPPNO_00839 1.4e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPDMPPNO_00840 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
NPDMPPNO_00841 8.3e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPDMPPNO_00842 1.5e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPDMPPNO_00843 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPDMPPNO_00844 1.9e-274 5.1.3.2 GM Psort location CytoplasmicMembrane, score
NPDMPPNO_00845 1.5e-145
NPDMPPNO_00846 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
NPDMPPNO_00847 6.1e-271 pelF GT4 M Domain of unknown function (DUF3492)
NPDMPPNO_00848 1.4e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
NPDMPPNO_00849 5.9e-223 cotH M CotH kinase protein
NPDMPPNO_00850 6e-97 P VTC domain
NPDMPPNO_00851 2e-83 S membrane
NPDMPPNO_00852 3.2e-134 G Domain of unknown function (DUF4832)
NPDMPPNO_00853 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPDMPPNO_00854 2.8e-11 S Protein of unknown function (DUF1146)
NPDMPPNO_00855 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPDMPPNO_00856 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
NPDMPPNO_00857 3.2e-153 endA F DNA RNA non-specific endonuclease
NPDMPPNO_00858 2.9e-111 tcyB_2 P ABC transporter (permease)
NPDMPPNO_00859 7.2e-116 gltJ P ABC transporter (Permease
NPDMPPNO_00860 2.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPDMPPNO_00861 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_00862 1.5e-110 tcyB_2 P ABC transporter (permease)
NPDMPPNO_00863 1.9e-116 gltJ P ABC transporter (Permease
NPDMPPNO_00864 1.9e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPDMPPNO_00865 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_00866 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDMPPNO_00867 7.6e-231 vicK 2.7.13.3 T Histidine kinase
NPDMPPNO_00868 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NPDMPPNO_00869 6.7e-57 S Protein of unknown function (DUF454)
NPDMPPNO_00870 3.5e-227 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NPDMPPNO_00871 4.6e-146 yidA S hydrolases of the HAD superfamily
NPDMPPNO_00872 4e-148 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
NPDMPPNO_00873 1e-66 ywiB S Domain of unknown function (DUF1934)
NPDMPPNO_00874 0.0 pacL 3.6.3.8 P cation transport ATPase
NPDMPPNO_00875 3.5e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPDMPPNO_00876 1.7e-156 yjjH S Calcineurin-like phosphoesterase
NPDMPPNO_00877 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPDMPPNO_00878 1.3e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPDMPPNO_00879 3.2e-124 ftsE D cell division ATP-binding protein FtsE
NPDMPPNO_00880 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NPDMPPNO_00881 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPDMPPNO_00882 5.6e-177 yubA S permease
NPDMPPNO_00883 3.1e-223 G COG0457 FOG TPR repeat
NPDMPPNO_00884 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPDMPPNO_00885 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPDMPPNO_00886 3.3e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPDMPPNO_00887 6.6e-87 ebsA S Family of unknown function (DUF5322)
NPDMPPNO_00888 2.5e-17 M LysM domain
NPDMPPNO_00889 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPDMPPNO_00890 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPDMPPNO_00891 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPDMPPNO_00892 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPDMPPNO_00893 2.5e-83 XK27_03610 K Gnat family
NPDMPPNO_00894 1.2e-91 yybC
NPDMPPNO_00895 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPDMPPNO_00896 1.3e-273 pepV 3.5.1.18 E Dipeptidase
NPDMPPNO_00897 5.5e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPDMPPNO_00898 1.2e-225 V Glucan-binding protein C
NPDMPPNO_00899 3.7e-252 V Glucan-binding protein C
NPDMPPNO_00900 4.3e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPDMPPNO_00901 1.5e-233 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPDMPPNO_00902 3.2e-95 S Protein of unknown function (DUF1697)
NPDMPPNO_00903 1.1e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPDMPPNO_00904 1.7e-171 clcA_2 P Chloride transporter, ClC family
NPDMPPNO_00905 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
NPDMPPNO_00906 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NPDMPPNO_00907 3.6e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NPDMPPNO_00908 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NPDMPPNO_00909 3.8e-109 cps4C M biosynthesis protein
NPDMPPNO_00910 1.8e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
NPDMPPNO_00911 4.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NPDMPPNO_00912 1.3e-221 rgpAc GT4 M group 1 family protein
NPDMPPNO_00913 2.6e-211 wcoF M Glycosyltransferase, group 1 family protein
NPDMPPNO_00914 1.2e-117 Z012_10770 M Domain of unknown function (DUF1919)
NPDMPPNO_00915 9e-165 M Glycosyltransferase, group 2 family protein
NPDMPPNO_00916 3e-131 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NPDMPPNO_00917 3.3e-171 M Glycosyltransferase
NPDMPPNO_00918 2.9e-173 S glycosyl transferase family 2
NPDMPPNO_00919 6e-214
NPDMPPNO_00920 1.1e-227 S Polysaccharide biosynthesis protein
NPDMPPNO_00921 1e-204 M transferase activity, transferring glycosyl groups
NPDMPPNO_00922 1.1e-147 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NPDMPPNO_00923 4.1e-107 pgm G Belongs to the phosphoglycerate mutase family
NPDMPPNO_00924 6.3e-108 G Belongs to the phosphoglycerate mutase family
NPDMPPNO_00925 1.4e-107 G Belongs to the phosphoglycerate mutase family
NPDMPPNO_00926 1.6e-197 S hmm pf01594
NPDMPPNO_00927 3.6e-287 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPDMPPNO_00928 4.9e-39 S granule-associated protein
NPDMPPNO_00929 2.3e-287 S unusual protein kinase
NPDMPPNO_00930 1.6e-98 estA E Lysophospholipase L1 and related esterases
NPDMPPNO_00931 1e-156 rssA S Phospholipase, patatin family
NPDMPPNO_00932 6.1e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NPDMPPNO_00933 9.3e-245 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NPDMPPNO_00934 1.6e-211 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPDMPPNO_00935 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPDMPPNO_00936 3.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPDMPPNO_00937 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NPDMPPNO_00938 3e-224 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_00939 9.8e-204 hpk9 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_00940 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NPDMPPNO_00941 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPDMPPNO_00942 7.1e-169 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPDMPPNO_00943 1.5e-272 lpdA 1.8.1.4 C Dehydrogenase
NPDMPPNO_00944 0.0 3.5.1.28 NU amidase activity
NPDMPPNO_00945 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
NPDMPPNO_00946 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NPDMPPNO_00947 1.7e-138 ycdO P periplasmic lipoprotein involved in iron transport
NPDMPPNO_00948 1.8e-231 ycdB P peroxidase
NPDMPPNO_00949 3.7e-291 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NPDMPPNO_00950 2.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPDMPPNO_00951 1.9e-23 tatA U protein secretion
NPDMPPNO_00952 2e-211 msmX P Belongs to the ABC transporter superfamily
NPDMPPNO_00953 9.8e-152 malG P ABC transporter (Permease
NPDMPPNO_00954 1.7e-249 malF P ABC transporter (Permease
NPDMPPNO_00955 3.9e-229 malX G ABC transporter
NPDMPPNO_00956 1e-171 malR K Transcriptional regulator
NPDMPPNO_00957 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NPDMPPNO_00958 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPDMPPNO_00959 1.9e-223 L Transposase
NPDMPPNO_00960 1.2e-38
NPDMPPNO_00961 6.1e-185 lplA 6.3.1.20 H Lipoate-protein ligase
NPDMPPNO_00962 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NPDMPPNO_00963 0.0 pepN 3.4.11.2 E aminopeptidase
NPDMPPNO_00964 9.2e-113 phoU P Plays a role in the regulation of phosphate uptake
NPDMPPNO_00965 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPDMPPNO_00966 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPDMPPNO_00967 1.3e-154 pstA P phosphate transport system permease
NPDMPPNO_00968 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NPDMPPNO_00969 3.1e-156 pstS P phosphate
NPDMPPNO_00970 2.2e-246 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NPDMPPNO_00971 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NPDMPPNO_00972 3e-44 yktA S Belongs to the UPF0223 family
NPDMPPNO_00973 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPDMPPNO_00974 8.7e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPDMPPNO_00975 1.1e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPDMPPNO_00976 1.4e-240 XK27_04775 S hemerythrin HHE cation binding domain
NPDMPPNO_00977 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
NPDMPPNO_00978 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NPDMPPNO_00979 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPDMPPNO_00980 2.5e-138 S haloacid dehalogenase-like hydrolase
NPDMPPNO_00981 7.3e-239 metY 2.5.1.49 E o-acetylhomoserine
NPDMPPNO_00982 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPDMPPNO_00983 9e-240 agcS E (Alanine) symporter
NPDMPPNO_00984 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPDMPPNO_00985 3.9e-176 bglC K Transcriptional regulator
NPDMPPNO_00986 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NPDMPPNO_00987 2.4e-81 yecS P ABC transporter (Permease
NPDMPPNO_00988 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
NPDMPPNO_00989 3.3e-240 nylA 3.5.1.4 J Belongs to the amidase family
NPDMPPNO_00990 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPDMPPNO_00991 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPDMPPNO_00994 1.4e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPDMPPNO_00995 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NPDMPPNO_00996 1e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NPDMPPNO_00997 4.4e-133 S TraX protein
NPDMPPNO_00998 5.1e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NPDMPPNO_00999 6.2e-261 S Psort location CytoplasmicMembrane, score
NPDMPPNO_01000 1.2e-231 dinF V Mate efflux family protein
NPDMPPNO_01001 2.9e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
NPDMPPNO_01002 1.7e-56 S von Willebrand factor (vWF) type A domain
NPDMPPNO_01003 6.3e-70 S von Willebrand factor (vWF) type A domain
NPDMPPNO_01004 0.0 V Type III restriction enzyme, res subunit
NPDMPPNO_01005 4e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NPDMPPNO_01006 1.4e-133 2.4.2.3 F Phosphorylase superfamily
NPDMPPNO_01007 5.1e-105 K Bacterial regulatory proteins, tetR family
NPDMPPNO_01008 7.1e-179 ybhR V ABC transporter
NPDMPPNO_01009 4.8e-123 ybhF_2 V abc transporter atp-binding protein
NPDMPPNO_01010 1.4e-187 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
NPDMPPNO_01011 1.2e-194 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NPDMPPNO_01012 1.7e-157 czcD P cation diffusion facilitator family transporter
NPDMPPNO_01013 4.6e-100 K Transcriptional regulator, TetR family
NPDMPPNO_01014 1.1e-70 S Protein of unknown function with HXXEE motif
NPDMPPNO_01015 4.9e-46
NPDMPPNO_01016 3.1e-73 L Transposase
NPDMPPNO_01017 0.0 S Signal peptide protein, YSIRK family
NPDMPPNO_01018 2e-126 K response regulator
NPDMPPNO_01019 1.2e-175 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NPDMPPNO_01020 1.7e-148 cbiO2 P ABC transporter, ATP-binding protein
NPDMPPNO_01021 1e-156 P abc transporter atp-binding protein
NPDMPPNO_01022 1.8e-131 cbiQ P cobalt transport
NPDMPPNO_01023 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
NPDMPPNO_01024 1.2e-138 S Phenazine biosynthesis protein
NPDMPPNO_01025 4.4e-92 tetR K transcriptional regulator
NPDMPPNO_01026 8.6e-125 V abc transporter atp-binding protein
NPDMPPNO_01027 0.0 V ABC transporter (Permease
NPDMPPNO_01028 1.1e-34 L Integrase core domain protein
NPDMPPNO_01029 5.9e-109 magIII L Base excision DNA repair protein, HhH-GPD family
NPDMPPNO_01030 1e-263 proWX P ABC transporter
NPDMPPNO_01031 3.5e-129 proV E abc transporter atp-binding protein
NPDMPPNO_01032 9.1e-145 1.6.5.2 GM NmrA-like family
NPDMPPNO_01033 1.1e-67 mgrA K Transcriptional regulator, MarR family
NPDMPPNO_01034 2.5e-77 S Macro domain
NPDMPPNO_01035 1.1e-97 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
NPDMPPNO_01036 4.4e-26 C Pyridoxamine 5'-phosphate oxidase
NPDMPPNO_01037 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NPDMPPNO_01038 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NPDMPPNO_01041 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPDMPPNO_01043 1.8e-136 IQ Acetoin reductase
NPDMPPNO_01044 2.6e-43 pspE P Rhodanese-like protein
NPDMPPNO_01045 2.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NPDMPPNO_01046 1e-223 XK27_05470 E Methionine synthase
NPDMPPNO_01047 1.1e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPDMPPNO_01048 3e-230 T PhoQ Sensor
NPDMPPNO_01049 1.9e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDMPPNO_01050 2.2e-151 S TraX protein
NPDMPPNO_01051 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPDMPPNO_01052 2.3e-156 dprA LU DNA protecting protein DprA
NPDMPPNO_01053 1e-165 GK ROK family
NPDMPPNO_01054 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPDMPPNO_01055 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPDMPPNO_01056 5.3e-127 K DNA-binding helix-turn-helix protein
NPDMPPNO_01057 6e-91 niaR S small molecule binding protein (contains 3H domain)
NPDMPPNO_01058 2.7e-86
NPDMPPNO_01059 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPDMPPNO_01060 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPDMPPNO_01061 2.7e-126 gntR1 K transcriptional
NPDMPPNO_01062 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPDMPPNO_01063 4.7e-216 K Putative DNA-binding domain
NPDMPPNO_01064 3.3e-34 V ABC transporter transmembrane region
NPDMPPNO_01065 9.4e-08
NPDMPPNO_01066 2.8e-21 yozG K Transcriptional regulator
NPDMPPNO_01067 6.8e-10 S Protein of unknown function (DUF2975)
NPDMPPNO_01069 1.4e-13 S Sigma-70, region 4
NPDMPPNO_01070 2.6e-44
NPDMPPNO_01071 2.6e-197 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPDMPPNO_01072 6.5e-52
NPDMPPNO_01073 5.5e-101 S Plasmid replication protein
NPDMPPNO_01074 1.9e-18 S Domain of unknown function (DUF3173)
NPDMPPNO_01075 2.7e-227 L Belongs to the 'phage' integrase family
NPDMPPNO_01076 8.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPDMPPNO_01077 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
NPDMPPNO_01078 6.7e-44
NPDMPPNO_01079 2.6e-51
NPDMPPNO_01080 2.6e-266 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDMPPNO_01081 1.3e-156 aatB ET ABC transporter substrate-binding protein
NPDMPPNO_01082 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_01083 3.1e-105 artQ P ABC transporter (Permease
NPDMPPNO_01084 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
NPDMPPNO_01085 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPDMPPNO_01086 8.4e-165 cpsY K Transcriptional regulator
NPDMPPNO_01087 1e-125 mur1 3.4.17.14, 3.5.1.28 NU muramidase
NPDMPPNO_01088 5.9e-159 yeiH S Membrane
NPDMPPNO_01090 2.6e-09
NPDMPPNO_01091 6.8e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
NPDMPPNO_01092 7.9e-146 XK27_10720 D peptidase activity
NPDMPPNO_01093 2.4e-275 pepD E Dipeptidase
NPDMPPNO_01094 2.2e-160 whiA K May be required for sporulation
NPDMPPNO_01095 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPDMPPNO_01096 2.2e-162 rapZ S Displays ATPase and GTPase activities
NPDMPPNO_01097 2.9e-134 yejC S cyclic nucleotide-binding protein
NPDMPPNO_01098 3.5e-200 D nuclear chromosome segregation
NPDMPPNO_01099 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NPDMPPNO_01100 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NPDMPPNO_01101 1.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NPDMPPNO_01102 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPDMPPNO_01103 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NPDMPPNO_01104 1.3e-19
NPDMPPNO_01105 1.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NPDMPPNO_01106 4.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NPDMPPNO_01107 1.1e-81 ypmB S Protein conserved in bacteria
NPDMPPNO_01108 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPDMPPNO_01109 1.7e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NPDMPPNO_01110 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPDMPPNO_01111 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
NPDMPPNO_01112 1.6e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NPDMPPNO_01113 1.2e-191 tcsA S membrane
NPDMPPNO_01114 4.8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NPDMPPNO_01115 1.8e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPDMPPNO_01116 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NPDMPPNO_01117 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
NPDMPPNO_01118 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NPDMPPNO_01119 1e-29 rpsT J Binds directly to 16S ribosomal RNA
NPDMPPNO_01120 9.8e-237 T PhoQ Sensor
NPDMPPNO_01121 6.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDMPPNO_01122 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPDMPPNO_01123 6.9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NPDMPPNO_01124 1.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPDMPPNO_01125 1.4e-93 panT S ECF transporter, substrate-specific component
NPDMPPNO_01126 2.9e-91 panT S Psort location CytoplasmicMembrane, score
NPDMPPNO_01127 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NPDMPPNO_01128 7.3e-166 metF 1.5.1.20 E reductase
NPDMPPNO_01129 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPDMPPNO_01131 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NPDMPPNO_01132 0.0 3.6.3.8 P cation transport ATPase
NPDMPPNO_01133 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPDMPPNO_01134 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDMPPNO_01135 1.2e-235 dltB M Membrane protein involved in D-alanine export
NPDMPPNO_01136 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPDMPPNO_01137 0.0 XK27_10035 V abc transporter atp-binding protein
NPDMPPNO_01138 3.8e-291 yfiB1 V abc transporter atp-binding protein
NPDMPPNO_01139 9.2e-99 pvaA M lytic transglycosylase activity
NPDMPPNO_01140 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
NPDMPPNO_01141 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPDMPPNO_01142 1.4e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPDMPPNO_01143 1.1e-139 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPDMPPNO_01144 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPDMPPNO_01145 3.3e-109 tdk 2.7.1.21 F thymidine kinase
NPDMPPNO_01146 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPDMPPNO_01147 1.1e-152 gst O Glutathione S-transferase
NPDMPPNO_01148 2.5e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NPDMPPNO_01149 4.6e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPDMPPNO_01150 4.4e-45 rpmE2 J 50S ribosomal protein L31
NPDMPPNO_01151 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
NPDMPPNO_01152 7.6e-164 ypuA S secreted protein
NPDMPPNO_01153 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NPDMPPNO_01154 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NPDMPPNO_01155 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPDMPPNO_01156 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPDMPPNO_01157 1.4e-256 noxE P NADH oxidase
NPDMPPNO_01158 4.3e-294 yfmM S abc transporter atp-binding protein
NPDMPPNO_01159 2.8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
NPDMPPNO_01160 2.6e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NPDMPPNO_01161 2.2e-85 S ECF-type riboflavin transporter, S component
NPDMPPNO_01163 4.4e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPDMPPNO_01164 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NPDMPPNO_01166 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPDMPPNO_01167 7.1e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDMPPNO_01168 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPDMPPNO_01169 2.3e-22 WQ51_00220 K Helix-turn-helix domain
NPDMPPNO_01170 1.4e-90 S Protein of unknown function (DUF3278)
NPDMPPNO_01171 0.0 smc D Required for chromosome condensation and partitioning
NPDMPPNO_01172 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPDMPPNO_01173 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPDMPPNO_01174 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPDMPPNO_01176 1.4e-295 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPDMPPNO_01177 2.1e-88 pat 2.3.1.183 M acetyltransferase
NPDMPPNO_01178 2.9e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPDMPPNO_01179 2.6e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NPDMPPNO_01180 4.2e-53
NPDMPPNO_01181 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPDMPPNO_01182 2.9e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NPDMPPNO_01183 1.7e-117 sdaAB 4.3.1.17 E L-serine dehydratase
NPDMPPNO_01184 9.9e-147 sdaAA 4.3.1.17 E L-serine dehydratase
NPDMPPNO_01185 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
NPDMPPNO_01186 2.2e-77 3.4.21.89 S RDD family
NPDMPPNO_01187 3.9e-154 K sequence-specific DNA binding
NPDMPPNO_01188 2.3e-50 ywrO S general stress protein
NPDMPPNO_01189 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
NPDMPPNO_01190 1.7e-76 yfiQ K Acetyltransferase (GNAT) domain
NPDMPPNO_01191 6.6e-142 S ABC-2 family transporter protein
NPDMPPNO_01192 4e-142 S ABC-2 family transporter protein
NPDMPPNO_01193 1.2e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
NPDMPPNO_01194 3e-86 L COG1943 Transposase and inactivated derivatives
NPDMPPNO_01195 5.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDMPPNO_01196 8.2e-191 desK 2.7.13.3 T Histidine kinase
NPDMPPNO_01197 9e-133 yvfS V ABC-2 type transporter
NPDMPPNO_01198 1.5e-158 XK27_09825 V abc transporter atp-binding protein
NPDMPPNO_01201 5.7e-172 fabH 2.3.1.180 I synthase III
NPDMPPNO_01202 3.6e-238 6.2.1.30 H Coenzyme F390 synthetase
NPDMPPNO_01203 3e-153 gumP S Metallo-beta-lactamase superfamily
NPDMPPNO_01204 1.3e-179 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
NPDMPPNO_01205 5e-232 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
NPDMPPNO_01206 8.9e-107 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPDMPPNO_01207 1.8e-193 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
NPDMPPNO_01208 2e-99
NPDMPPNO_01209 1.5e-207 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
NPDMPPNO_01211 1.5e-234 anK3 G response to abiotic stimulus
NPDMPPNO_01212 0.0 hscC O Belongs to the heat shock protein 70 family
NPDMPPNO_01213 3.3e-164 yocS S Transporter
NPDMPPNO_01214 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NPDMPPNO_01215 2.2e-115 yvfS V Transporter
NPDMPPNO_01216 5e-154 XK27_09825 V abc transporter atp-binding protein
NPDMPPNO_01217 3.7e-16 liaI KT membrane
NPDMPPNO_01218 5.8e-30 liaI KT membrane
NPDMPPNO_01219 6.1e-93 XK27_05000 S metal cluster binding
NPDMPPNO_01220 0.0 V ABC transporter (permease)
NPDMPPNO_01221 1.1e-133 macB2 V ABC transporter, ATP-binding protein
NPDMPPNO_01222 9.7e-151 T Histidine kinase
NPDMPPNO_01223 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPDMPPNO_01224 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPDMPPNO_01225 2.3e-221 pbuX F xanthine permease
NPDMPPNO_01226 6.8e-61 pdxH S pyridoxamine 5'-phosphate oxidase
NPDMPPNO_01227 1.8e-243 norM V Multidrug efflux pump
NPDMPPNO_01229 5.5e-175 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPDMPPNO_01230 4.9e-230 brnQ E Component of the transport system for branched-chain amino acids
NPDMPPNO_01231 9.6e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPDMPPNO_01232 1.8e-59 S Protein of unknown function (DUF3290)
NPDMPPNO_01233 1.5e-107 S Protein of unknown function (DUF421)
NPDMPPNO_01234 1.4e-16 csbD S CsbD-like
NPDMPPNO_01235 5.7e-105 S Carbohydrate-binding domain-containing protein Cthe_2159
NPDMPPNO_01236 1.7e-49 XK27_01300 P Protein conserved in bacteria
NPDMPPNO_01237 7.2e-216 yfnA E amino acid
NPDMPPNO_01238 0.0 S dextransucrase activity
NPDMPPNO_01239 5.6e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NPDMPPNO_01240 2e-42 S Sugar efflux transporter for intercellular exchange
NPDMPPNO_01241 1.2e-203 P FtsX-like permease family
NPDMPPNO_01242 1.3e-122 V abc transporter atp-binding protein
NPDMPPNO_01243 6.9e-96 K WHG domain
NPDMPPNO_01244 3.7e-168 ydhF S Aldo keto reductase
NPDMPPNO_01245 1.1e-06 S Protein of unknown function (DUF3169)
NPDMPPNO_01246 2.5e-27 XK27_07105 K transcriptional
NPDMPPNO_01247 2.7e-27
NPDMPPNO_01248 2.2e-108 XK27_02070 S nitroreductase
NPDMPPNO_01249 1.4e-150 1.13.11.2 S glyoxalase
NPDMPPNO_01250 2.5e-77 ywnA K Transcriptional regulator
NPDMPPNO_01251 1.2e-155 E Alpha/beta hydrolase of unknown function (DUF915)
NPDMPPNO_01252 1.2e-225 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDMPPNO_01253 2.4e-167 bcrA V abc transporter atp-binding protein
NPDMPPNO_01254 5.8e-127 S ABC-2 family transporter protein
NPDMPPNO_01255 1.5e-09
NPDMPPNO_01256 6.7e-07 S Tetratricopeptide repeats
NPDMPPNO_01259 1.2e-128 T PhoQ Sensor
NPDMPPNO_01260 3.3e-121 T Xre family transcriptional regulator
NPDMPPNO_01261 4.1e-110 drgA C nitroreductase
NPDMPPNO_01262 1.6e-104 yoaK S Protein of unknown function (DUF1275)
NPDMPPNO_01263 5.3e-40 DJ nuclease activity
NPDMPPNO_01264 1.1e-30 XK27_10490
NPDMPPNO_01265 1.6e-157 yvgN C reductase
NPDMPPNO_01266 2.3e-79 S Tetratricopeptide repeat
NPDMPPNO_01267 0.0 lacL 3.2.1.23 G -beta-galactosidase
NPDMPPNO_01268 0.0 lacS G transporter
NPDMPPNO_01269 3.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPDMPPNO_01270 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPDMPPNO_01271 2.6e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NPDMPPNO_01272 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPDMPPNO_01273 3.4e-175 galR K Transcriptional regulator
NPDMPPNO_01274 3.5e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
NPDMPPNO_01275 1.5e-228 vncS 2.7.13.3 T Histidine kinase
NPDMPPNO_01276 9.8e-115 K Response regulator receiver domain protein
NPDMPPNO_01277 1.4e-235 vex3 V Efflux ABC transporter, permease protein
NPDMPPNO_01278 7.3e-107 vex2 V abc transporter atp-binding protein
NPDMPPNO_01279 1.7e-211 vex1 V Efflux ABC transporter, permease protein
NPDMPPNO_01280 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
NPDMPPNO_01282 1.9e-195 gldA 1.1.1.6 C glycerol dehydrogenase
NPDMPPNO_01283 1.8e-176 XK27_10475 S oxidoreductase
NPDMPPNO_01284 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
NPDMPPNO_01285 1.2e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
NPDMPPNO_01286 1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
NPDMPPNO_01287 4.5e-225 thrE K Psort location CytoplasmicMembrane, score
NPDMPPNO_01288 0.0 M Putative cell wall binding repeat
NPDMPPNO_01289 6.4e-35 S Immunity protein 41
NPDMPPNO_01290 1.8e-08 S Enterocin A Immunity
NPDMPPNO_01291 1.3e-193 mccF V LD-carboxypeptidase
NPDMPPNO_01292 1.8e-14 S integral membrane protein
NPDMPPNO_01293 2.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
NPDMPPNO_01294 4.8e-118 yhfC S Putative membrane peptidase family (DUF2324)
NPDMPPNO_01295 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_01297 2.1e-245 S dextransucrase activity
NPDMPPNO_01298 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_01299 0.0 S dextransucrase activity
NPDMPPNO_01300 0.0 S dextransucrase activity
NPDMPPNO_01301 7.2e-89 S dextransucrase activity
NPDMPPNO_01302 1.6e-240 tcdB S dextransucrase activity
NPDMPPNO_01303 0.0 S dextransucrase activity
NPDMPPNO_01304 7.8e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NPDMPPNO_01305 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NPDMPPNO_01306 1.6e-301 S dextransucrase activity
NPDMPPNO_01307 0.0 S dextransucrase activity
NPDMPPNO_01308 2.8e-175 S dextransucrase activity
NPDMPPNO_01309 0.0 M Putative cell wall binding repeat
NPDMPPNO_01310 2.2e-223 M Putative cell wall binding repeat
NPDMPPNO_01311 4.6e-22 UW LPXTG-motif cell wall anchor domain protein
NPDMPPNO_01313 3.9e-123 XK27_00785 S CAAX protease self-immunity
NPDMPPNO_01314 1.8e-238 EGP Major facilitator Superfamily
NPDMPPNO_01315 6.2e-67 rmaI K Transcriptional regulator, MarR family
NPDMPPNO_01316 6.1e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
NPDMPPNO_01317 3.1e-133 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NPDMPPNO_01318 0.0 3.5.1.28 M domain protein
NPDMPPNO_01319 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
NPDMPPNO_01320 2.3e-22
NPDMPPNO_01326 4.8e-175 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
NPDMPPNO_01327 4.2e-254 sraP UW Hep Hag repeat protein
NPDMPPNO_01328 1.6e-185 nss M transferase activity, transferring glycosyl groups
NPDMPPNO_01329 3.6e-16 S Accessory secretory protein Sec, Asp5
NPDMPPNO_01330 2.6e-17 S Accessory secretory protein Sec Asp4
NPDMPPNO_01331 2.5e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPDMPPNO_01332 7.7e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPDMPPNO_01333 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPDMPPNO_01334 3.8e-78 asp3 S Accessory Sec system protein Asp3
NPDMPPNO_01335 2.4e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
NPDMPPNO_01336 2.5e-289 asp1 S Accessory Sec system protein Asp1
NPDMPPNO_01337 1.4e-210 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NPDMPPNO_01338 0.0 M family 8
NPDMPPNO_01339 0.0 sbcC L ATPase involved in DNA repair
NPDMPPNO_01340 1.1e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPDMPPNO_01341 0.0 GM domain, Protein
NPDMPPNO_01342 0.0 zmpB M signal peptide protein, YSIRK family
NPDMPPNO_01343 7.8e-118 fhaB M Rib/alpha-like repeat
NPDMPPNO_01344 0.0 M domain protein
NPDMPPNO_01345 1.2e-11
NPDMPPNO_01346 7.9e-192 XK27_10075 S abc transporter atp-binding protein
NPDMPPNO_01347 0.0 V abc transporter atp-binding protein
NPDMPPNO_01348 2.7e-297 V abc transporter atp-binding protein
NPDMPPNO_01349 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NPDMPPNO_01351 6.1e-285 S Protein of unknown function (DUF3114)
NPDMPPNO_01352 1e-96 2.3.1.128 K Acetyltransferase GNAT Family
NPDMPPNO_01353 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPDMPPNO_01354 2.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPDMPPNO_01355 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
NPDMPPNO_01356 2.2e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPDMPPNO_01357 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPDMPPNO_01358 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NPDMPPNO_01359 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPDMPPNO_01360 3.9e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NPDMPPNO_01361 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPDMPPNO_01362 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPDMPPNO_01365 1.2e-112 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPDMPPNO_01366 4.3e-170 vraS 2.7.13.3 T Histidine kinase
NPDMPPNO_01367 3.3e-116 yvqF S Membrane
NPDMPPNO_01368 9e-104 kcsA P Ion transport protein
NPDMPPNO_01369 1.4e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
NPDMPPNO_01370 2e-135 stp 3.1.3.16 T phosphatase
NPDMPPNO_01371 9.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPDMPPNO_01372 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPDMPPNO_01373 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPDMPPNO_01374 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NPDMPPNO_01375 5.7e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NPDMPPNO_01376 1.4e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPDMPPNO_01377 2.8e-143 XK27_02985 S overlaps another CDS with the same product name
NPDMPPNO_01378 5e-145 supH S overlaps another CDS with the same product name
NPDMPPNO_01379 2.1e-61 yvoA_1 K Transcriptional
NPDMPPNO_01380 5.4e-119 skfE V abc transporter atp-binding protein
NPDMPPNO_01381 4.5e-130 V Psort location CytoplasmicMembrane, score
NPDMPPNO_01382 4.7e-171 oppF P Belongs to the ABC transporter superfamily
NPDMPPNO_01383 8.7e-201 oppD P Belongs to the ABC transporter superfamily
NPDMPPNO_01384 3.1e-167 amiD P ABC transporter (Permease
NPDMPPNO_01385 7.1e-278 amiC P ABC transporter (Permease
NPDMPPNO_01386 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
NPDMPPNO_01387 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NPDMPPNO_01388 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPDMPPNO_01389 3.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NPDMPPNO_01390 1.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPDMPPNO_01391 1.1e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NPDMPPNO_01392 2.4e-101 yjbK S Adenylate cyclase
NPDMPPNO_01393 3.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPDMPPNO_01394 7.5e-208 iscS 2.8.1.7 E Cysteine desulfurase
NPDMPPNO_01395 8.2e-60 XK27_04120 S Putative amino acid metabolism
NPDMPPNO_01396 7.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPDMPPNO_01397 8.2e-128 puuD T peptidase C26
NPDMPPNO_01398 1.5e-118 radC E Belongs to the UPF0758 family
NPDMPPNO_01399 4e-306 rgpF M Rhamnan synthesis protein F
NPDMPPNO_01400 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPDMPPNO_01401 4.4e-141 rgpC GM Transport permease protein
NPDMPPNO_01402 1.9e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
NPDMPPNO_01403 3.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
NPDMPPNO_01404 1.5e-225 GT4 M transferase activity, transferring glycosyl groups
NPDMPPNO_01405 7.3e-220 M Psort location CytoplasmicMembrane, score
NPDMPPNO_01406 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
NPDMPPNO_01407 2.8e-123
NPDMPPNO_01408 3.2e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
NPDMPPNO_01409 1.4e-43 S Uncharacterized conserved protein (DUF2304)
NPDMPPNO_01410 3.2e-127 arnC M group 2 family protein
NPDMPPNO_01411 1.6e-177 cpsIaJ S Glycosyltransferase like family 2
NPDMPPNO_01412 6.3e-155 M Glycosyltransferase, group 2 family protein
NPDMPPNO_01413 8.4e-227 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NPDMPPNO_01414 6.5e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPDMPPNO_01415 9.2e-262 S Glucosyl transferase GtrII
NPDMPPNO_01416 2.3e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NPDMPPNO_01417 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NPDMPPNO_01418 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPDMPPNO_01419 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPDMPPNO_01420 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPDMPPNO_01421 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPDMPPNO_01422 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
NPDMPPNO_01423 1.3e-199 arcT 2.6.1.1 E Aminotransferase
NPDMPPNO_01424 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
NPDMPPNO_01425 2.2e-140 ET ABC transporter
NPDMPPNO_01426 1.8e-78 mutT 3.6.1.55 F Nudix family
NPDMPPNO_01427 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPDMPPNO_01429 2.1e-163 S CAAX amino terminal protease family protein
NPDMPPNO_01430 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NPDMPPNO_01431 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_01432 1.7e-17 XK27_00735
NPDMPPNO_01433 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPDMPPNO_01435 1e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPDMPPNO_01436 7.5e-10 O ADP-ribosylglycohydrolase
NPDMPPNO_01437 2.1e-61 paaI Q protein possibly involved in aromatic compounds catabolism
NPDMPPNO_01438 2.4e-62 ycaO O OsmC-like protein
NPDMPPNO_01440 3.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
NPDMPPNO_01441 2.5e-07 N PFAM Uncharacterised protein family UPF0150
NPDMPPNO_01442 1.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
NPDMPPNO_01443 7.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPDMPPNO_01444 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPDMPPNO_01445 1.3e-94 3.1.3.18 S IA, variant 1
NPDMPPNO_01446 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPDMPPNO_01447 1e-55 lrgA S Effector of murein hydrolase LrgA
NPDMPPNO_01449 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
NPDMPPNO_01450 1.3e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NPDMPPNO_01451 2.2e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPDMPPNO_01452 2.5e-103 wecD M Acetyltransferase (GNAT) domain
NPDMPPNO_01453 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPDMPPNO_01454 5.4e-156 GK ROK family
NPDMPPNO_01455 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
NPDMPPNO_01456 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
NPDMPPNO_01457 1.3e-204 potD P spermidine putrescine ABC transporter
NPDMPPNO_01458 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
NPDMPPNO_01459 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
NPDMPPNO_01460 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPDMPPNO_01461 1.4e-167 murB 1.3.1.98 M cell wall formation
NPDMPPNO_01462 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NPDMPPNO_01463 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPDMPPNO_01464 3.5e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NPDMPPNO_01465 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPDMPPNO_01466 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
NPDMPPNO_01467 0.0 ydaO E amino acid
NPDMPPNO_01468 1e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPDMPPNO_01469 1.5e-36 ylqC L Belongs to the UPF0109 family
NPDMPPNO_01470 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPDMPPNO_01472 6.2e-201 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01473 7.6e-124 agrA KT phosphorelay signal transduction system
NPDMPPNO_01474 3.9e-163 O protein import
NPDMPPNO_01475 3.6e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NPDMPPNO_01476 3.7e-17 yjdB S Domain of unknown function (DUF4767)
NPDMPPNO_01477 3.1e-62 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPDMPPNO_01479 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NPDMPPNO_01480 4.9e-71 S QueT transporter
NPDMPPNO_01482 1.2e-169 yfjR K regulation of single-species biofilm formation
NPDMPPNO_01484 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPDMPPNO_01485 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPDMPPNO_01486 3.7e-85 ccl S cog cog4708
NPDMPPNO_01487 1.1e-159 rbn E Belongs to the UPF0761 family
NPDMPPNO_01488 2.1e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NPDMPPNO_01489 3e-232 ytoI K transcriptional regulator containing CBS domains
NPDMPPNO_01490 2.6e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NPDMPPNO_01491 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPDMPPNO_01492 0.0 comEC S Competence protein ComEC
NPDMPPNO_01493 3.9e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NPDMPPNO_01494 8.3e-142 plsC 2.3.1.51 I Acyltransferase
NPDMPPNO_01495 5.8e-161 nodB3 G deacetylase
NPDMPPNO_01496 3.4e-127 yabB 2.1.1.223 L Methyltransferase
NPDMPPNO_01497 2.3e-41 yazA L endonuclease containing a URI domain
NPDMPPNO_01498 2.8e-26 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
NPDMPPNO_01499 1.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPDMPPNO_01500 1.3e-152 corA P CorA-like protein
NPDMPPNO_01501 3.3e-62 yjqA S Bacterial PH domain
NPDMPPNO_01502 1.5e-98 thiT S Thiamine transporter
NPDMPPNO_01503 2.5e-150 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NPDMPPNO_01504 8.9e-191 yjbB G Permeases of the major facilitator superfamily
NPDMPPNO_01505 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPDMPPNO_01506 2.8e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
NPDMPPNO_01510 1.2e-28
NPDMPPNO_01512 2.6e-22 S Psort location Cytoplasmic, score
NPDMPPNO_01513 1e-251 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPDMPPNO_01517 1.7e-154 cjaA ET ABC transporter substrate-binding protein
NPDMPPNO_01518 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_01519 3e-106 P ABC transporter (Permease
NPDMPPNO_01520 3e-114 papP P ABC transporter (Permease
NPDMPPNO_01521 6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPDMPPNO_01522 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
NPDMPPNO_01523 0.0 copA 3.6.3.54 P P-type ATPase
NPDMPPNO_01524 5.2e-72 copY K negative regulation of transcription, DNA-templated
NPDMPPNO_01525 2.8e-173 EGP Major facilitator Superfamily
NPDMPPNO_01527 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPDMPPNO_01528 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPDMPPNO_01529 4.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NPDMPPNO_01530 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NPDMPPNO_01531 1.1e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPDMPPNO_01532 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NPDMPPNO_01533 5.3e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPDMPPNO_01534 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NPDMPPNO_01535 7.5e-59
NPDMPPNO_01536 0.0 ctpE P E1-E2 ATPase
NPDMPPNO_01537 9e-47
NPDMPPNO_01538 1.5e-49
NPDMPPNO_01539 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPDMPPNO_01541 1.9e-124 V abc transporter atp-binding protein
NPDMPPNO_01542 0.0 V ABC transporter (Permease
NPDMPPNO_01543 3.1e-125 K transcriptional regulator, MerR family
NPDMPPNO_01544 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
NPDMPPNO_01545 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
NPDMPPNO_01546 2.8e-63 XK27_02560 S cog cog2151
NPDMPPNO_01547 1.5e-62
NPDMPPNO_01548 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NPDMPPNO_01549 2.1e-213 ytfP S Flavoprotein
NPDMPPNO_01551 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPDMPPNO_01552 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
NPDMPPNO_01553 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
NPDMPPNO_01554 2.2e-131 ecsA V abc transporter atp-binding protein
NPDMPPNO_01555 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NPDMPPNO_01558 1.6e-103
NPDMPPNO_01560 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NPDMPPNO_01561 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
NPDMPPNO_01562 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPDMPPNO_01563 2.9e-196 ylbM S Belongs to the UPF0348 family
NPDMPPNO_01564 8.4e-139 yqeM Q Methyltransferase domain protein
NPDMPPNO_01565 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPDMPPNO_01566 7.8e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NPDMPPNO_01567 2.3e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPDMPPNO_01568 7.7e-49 yhbY J RNA-binding protein
NPDMPPNO_01569 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NPDMPPNO_01570 5.1e-98 yqeG S hydrolase of the HAD superfamily
NPDMPPNO_01571 8.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPDMPPNO_01572 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NPDMPPNO_01573 1.1e-60
NPDMPPNO_01574 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPDMPPNO_01575 1.5e-57
NPDMPPNO_01576 8.5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
NPDMPPNO_01577 2.2e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
NPDMPPNO_01578 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
NPDMPPNO_01579 7.2e-31 S PQ loop repeat
NPDMPPNO_01580 1.2e-36 S Sulfite exporter TauE/SafE
NPDMPPNO_01581 2.7e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPDMPPNO_01583 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPDMPPNO_01584 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPDMPPNO_01585 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPDMPPNO_01586 3.1e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NPDMPPNO_01587 1.6e-188 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NPDMPPNO_01588 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
NPDMPPNO_01589 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NPDMPPNO_01590 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPDMPPNO_01591 8.3e-99 pncA Q isochorismatase
NPDMPPNO_01592 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NPDMPPNO_01593 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NPDMPPNO_01594 9e-75 XK27_03180 T universal stress protein
NPDMPPNO_01596 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPDMPPNO_01597 7.4e-10 MU outer membrane autotransporter barrel domain protein
NPDMPPNO_01598 1.4e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NPDMPPNO_01599 1.5e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NPDMPPNO_01601 7.9e-25
NPDMPPNO_01603 0.0 yjcE P NhaP-type Na H and K H antiporters
NPDMPPNO_01605 2.7e-97 ytqB J (SAM)-dependent
NPDMPPNO_01606 5.4e-183 yhcC S radical SAM protein
NPDMPPNO_01607 3.2e-187 ylbL T Belongs to the peptidase S16 family
NPDMPPNO_01608 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPDMPPNO_01609 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
NPDMPPNO_01610 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPDMPPNO_01611 5e-10 S Protein of unknown function (DUF4059)
NPDMPPNO_01612 9.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
NPDMPPNO_01613 2.3e-162 yxeN P ABC transporter (Permease
NPDMPPNO_01614 3.3e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPDMPPNO_01615 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPDMPPNO_01616 6.1e-35
NPDMPPNO_01617 1.1e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPDMPPNO_01618 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NPDMPPNO_01619 2.7e-143 cah 4.2.1.1 P carbonic anhydrase
NPDMPPNO_01620 5.3e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPDMPPNO_01622 6.9e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NPDMPPNO_01623 3.2e-141 cppA E CppA N-terminal
NPDMPPNO_01624 4.5e-107 V CAAX protease self-immunity
NPDMPPNO_01625 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NPDMPPNO_01626 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPDMPPNO_01627 6.7e-07
NPDMPPNO_01629 3.7e-45 spiA K sequence-specific DNA binding
NPDMPPNO_01632 1.8e-133 agrA KT LytTr DNA-binding domain
NPDMPPNO_01633 1.9e-218 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NPDMPPNO_01638 1.5e-25 S Bacteriocin class II with double-glycine leader peptide
NPDMPPNO_01639 0.0 mdlB V abc transporter atp-binding protein
NPDMPPNO_01640 0.0 mdlA V abc transporter atp-binding protein
NPDMPPNO_01643 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
NPDMPPNO_01644 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPDMPPNO_01645 4.8e-62 yutD J protein conserved in bacteria
NPDMPPNO_01646 3.8e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPDMPPNO_01648 3.7e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPDMPPNO_01649 3.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPDMPPNO_01650 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NPDMPPNO_01651 2.4e-45 ftsL D cell division protein FtsL
NPDMPPNO_01652 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPDMPPNO_01653 6.9e-94
NPDMPPNO_01655 1.4e-35 yhaI J Protein of unknown function (DUF805)
NPDMPPNO_01656 7.7e-62 yhaI J Protein of unknown function (DUF805)
NPDMPPNO_01657 7.1e-60 yhaI J Membrane
NPDMPPNO_01658 6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPDMPPNO_01659 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPDMPPNO_01660 1.4e-271 XK27_00765
NPDMPPNO_01661 8.9e-133 ecsA_2 V abc transporter atp-binding protein
NPDMPPNO_01662 3.1e-125 S Protein of unknown function (DUF554)
NPDMPPNO_01663 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPDMPPNO_01664 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NPDMPPNO_01665 8.6e-246 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01666 8.5e-235 dcuS 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01667 5.2e-14
NPDMPPNO_01670 5.8e-146 V Psort location CytoplasmicMembrane, score
NPDMPPNO_01672 6.6e-298 O MreB/Mbl protein
NPDMPPNO_01673 2e-118 liaI S membrane
NPDMPPNO_01674 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
NPDMPPNO_01675 4.8e-311 KT response to antibiotic
NPDMPPNO_01676 3.2e-100 yebC M Membrane
NPDMPPNO_01677 6.8e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
NPDMPPNO_01678 9.2e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NPDMPPNO_01680 2.9e-31 yozG K Transcriptional regulator
NPDMPPNO_01684 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPDMPPNO_01685 2.6e-200 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPDMPPNO_01686 5.8e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPDMPPNO_01687 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NPDMPPNO_01688 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NPDMPPNO_01689 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPDMPPNO_01691 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPDMPPNO_01692 3.8e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NPDMPPNO_01693 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NPDMPPNO_01694 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
NPDMPPNO_01695 9.2e-178 scrR K Transcriptional regulator
NPDMPPNO_01696 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPDMPPNO_01697 1.7e-61 yqhY S protein conserved in bacteria
NPDMPPNO_01698 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPDMPPNO_01699 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
NPDMPPNO_01700 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NPDMPPNO_01701 2.8e-32 blpT
NPDMPPNO_01705 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NPDMPPNO_01706 1e-168 corA P COG0598 Mg2 and Co2 transporters
NPDMPPNO_01707 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
NPDMPPNO_01709 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPDMPPNO_01710 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPDMPPNO_01711 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NPDMPPNO_01712 3.8e-43 XK27_05745
NPDMPPNO_01713 6.8e-220 mutY L A G-specific adenine glycosylase
NPDMPPNO_01715 1.5e-35
NPDMPPNO_01717 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPDMPPNO_01718 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPDMPPNO_01719 6.1e-94 cvpA S toxin biosynthetic process
NPDMPPNO_01720 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPDMPPNO_01721 5e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPDMPPNO_01722 7.4e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPDMPPNO_01723 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPDMPPNO_01724 1.3e-46 azlD S branched-chain amino acid
NPDMPPNO_01725 9.7e-113 azlC E AzlC protein
NPDMPPNO_01726 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPDMPPNO_01727 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPDMPPNO_01728 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NPDMPPNO_01729 1.5e-33 ykzG S Belongs to the UPF0356 family
NPDMPPNO_01730 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPDMPPNO_01731 2.4e-49 L COG1943 Transposase and inactivated derivatives
NPDMPPNO_01732 9.5e-115 pscB M CHAP domain protein
NPDMPPNO_01733 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
NPDMPPNO_01734 2.5e-62 glnR K Transcriptional regulator
NPDMPPNO_01735 6.7e-87 S Fusaric acid resistance protein-like
NPDMPPNO_01736 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPDMPPNO_01737 1.9e-186 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPDMPPNO_01738 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPDMPPNO_01739 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPDMPPNO_01740 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPDMPPNO_01741 4e-142 purR 2.4.2.7 F operon repressor
NPDMPPNO_01742 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
NPDMPPNO_01743 3.2e-170 rmuC S RmuC domain protein
NPDMPPNO_01744 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPDMPPNO_01745 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPDMPPNO_01746 3.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPDMPPNO_01748 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPDMPPNO_01749 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPDMPPNO_01750 3.6e-143 tatD L Hydrolase, tatd
NPDMPPNO_01751 1.2e-73 yccU S CoA-binding protein
NPDMPPNO_01752 2.4e-50 trxA O Belongs to the thioredoxin family
NPDMPPNO_01753 1.7e-142 S Macro domain protein
NPDMPPNO_01754 1.8e-61 L thioesterase
NPDMPPNO_01755 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
NPDMPPNO_01758 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPDMPPNO_01759 3.4e-14 rpmH J Ribosomal protein L34
NPDMPPNO_01760 2.8e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
NPDMPPNO_01761 1.1e-104 K Transcriptional regulator
NPDMPPNO_01762 1.2e-151 jag S RNA-binding protein
NPDMPPNO_01763 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPDMPPNO_01764 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPDMPPNO_01765 1.7e-262 argH 4.3.2.1 E Argininosuccinate lyase
NPDMPPNO_01766 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPDMPPNO_01767 7.2e-130 fasA KT Response regulator of the LytR AlgR family
NPDMPPNO_01768 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01769 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01770 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
NPDMPPNO_01771 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NPDMPPNO_01772 6.7e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPDMPPNO_01773 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NPDMPPNO_01774 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPDMPPNO_01775 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPDMPPNO_01776 1.2e-50 S Protein of unknown function (DUF3397)
NPDMPPNO_01777 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NPDMPPNO_01778 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
NPDMPPNO_01779 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPDMPPNO_01780 8.7e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NPDMPPNO_01781 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NPDMPPNO_01782 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
NPDMPPNO_01783 2.1e-230 XK27_09615 C reductase
NPDMPPNO_01784 2e-138 fnt P Formate nitrite transporter
NPDMPPNO_01785 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
NPDMPPNO_01786 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPDMPPNO_01787 6.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPDMPPNO_01788 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NPDMPPNO_01789 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPDMPPNO_01790 1.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPDMPPNO_01791 1e-56 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPDMPPNO_01792 1.6e-137 S HAD hydrolase, family IA, variant
NPDMPPNO_01793 9.2e-158 rrmA 2.1.1.187 Q methyltransferase
NPDMPPNO_01797 3.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPDMPPNO_01798 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPDMPPNO_01799 8.3e-37 yeeD O sulfur carrier activity
NPDMPPNO_01800 2e-186 yeeE S Sulphur transport
NPDMPPNO_01801 2.5e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPDMPPNO_01802 2.6e-09 S NTF2 fold immunity protein
NPDMPPNO_01803 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPDMPPNO_01804 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
NPDMPPNO_01805 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NPDMPPNO_01806 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPDMPPNO_01807 2.2e-93 S CAAX amino terminal protease family protein
NPDMPPNO_01809 1.4e-108 V CAAX protease self-immunity
NPDMPPNO_01810 8.8e-27 lanR K sequence-specific DNA binding
NPDMPPNO_01811 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPDMPPNO_01812 3.8e-176 ytxK 2.1.1.72 L DNA methylase
NPDMPPNO_01813 1.5e-12 comGF U Putative Competence protein ComGF
NPDMPPNO_01814 9.9e-71 comGF U Competence protein ComGF
NPDMPPNO_01815 5.3e-15 NU Type II secretory pathway pseudopilin
NPDMPPNO_01816 8.4e-70 cglD NU Competence protein
NPDMPPNO_01817 2.2e-43 comGC U Required for transformation and DNA binding
NPDMPPNO_01818 7.4e-144 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPDMPPNO_01819 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPDMPPNO_01820 3.8e-68 S cog cog4699
NPDMPPNO_01821 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDMPPNO_01822 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDMPPNO_01823 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPDMPPNO_01824 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPDMPPNO_01825 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NPDMPPNO_01826 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
NPDMPPNO_01827 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NPDMPPNO_01828 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NPDMPPNO_01829 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
NPDMPPNO_01830 1.4e-57 asp S cog cog1302
NPDMPPNO_01831 4.6e-225 norN V Mate efflux family protein
NPDMPPNO_01832 9.2e-278 thrC 4.2.3.1 E Threonine synthase
NPDMPPNO_01835 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPDMPPNO_01836 0.0 pepO 3.4.24.71 O Peptidase family M13
NPDMPPNO_01837 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NPDMPPNO_01838 7.7e-112 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NPDMPPNO_01839 7.4e-166 treB 2.7.1.201 G pts system
NPDMPPNO_01840 6e-126 treR K trehalose operon
NPDMPPNO_01841 4.3e-95 ywlG S Belongs to the UPF0340 family
NPDMPPNO_01844 2.3e-70
NPDMPPNO_01845 2.5e-106 S Domain of unknown function (DUF4336)
NPDMPPNO_01846 1.6e-97 CG glycosyl
NPDMPPNO_01848 2.7e-102 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPDMPPNO_01849 1.2e-108 V Efflux ABC transporter permease protein
NPDMPPNO_01850 1.4e-55 V abc transporter atp-binding protein
NPDMPPNO_01851 1.1e-60 2.1.1.72 J protein-(glutamine-N5) methyltransferase activity
NPDMPPNO_01852 1.5e-144 rkpG 2.3.1.47 E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPDMPPNO_01853 2.9e-109 K Peptidase S24-like
NPDMPPNO_01854 1.9e-134 E IrrE N-terminal-like domain
NPDMPPNO_01856 2.9e-46 K Bacteriophage CI repressor helix-turn-helix domain
NPDMPPNO_01857 3.5e-43
NPDMPPNO_01858 5e-73
NPDMPPNO_01859 1.7e-267 ydcQ D FtsK/SpoIIIE family
NPDMPPNO_01860 1.3e-38
NPDMPPNO_01861 1.2e-17
NPDMPPNO_01862 1.2e-11 K Transcriptional
NPDMPPNO_01864 1.3e-63 L Replication initiation factor
NPDMPPNO_01865 4.5e-10 S Domain of unknown function (DUF3173)
NPDMPPNO_01866 6.7e-212 L Belongs to the 'phage' integrase family
NPDMPPNO_01867 1.8e-223 K Replication initiation factor
NPDMPPNO_01868 1.5e-33
NPDMPPNO_01869 1.5e-87
NPDMPPNO_01870 1.1e-160 S Conjugative transposon protein TcpC
NPDMPPNO_01871 3.2e-33
NPDMPPNO_01872 5.1e-69 S TcpE family
NPDMPPNO_01873 0.0 yddE S AAA-like domain
NPDMPPNO_01874 8.1e-255
NPDMPPNO_01875 9.7e-30
NPDMPPNO_01876 4.8e-170 isp2 S pathogenesis
NPDMPPNO_01877 4e-16
NPDMPPNO_01878 1.2e-183 L Phage integrase family
NPDMPPNO_01879 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NPDMPPNO_01881 3.9e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
NPDMPPNO_01882 4.4e-62 rplQ J ribosomal protein l17
NPDMPPNO_01883 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPDMPPNO_01884 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPDMPPNO_01885 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPDMPPNO_01886 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPDMPPNO_01887 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPDMPPNO_01888 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPDMPPNO_01889 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPDMPPNO_01890 5.7e-58 rplO J binds to the 23S rRNA
NPDMPPNO_01891 1.9e-23 rpmD J ribosomal protein l30
NPDMPPNO_01892 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPDMPPNO_01893 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPDMPPNO_01894 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPDMPPNO_01895 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPDMPPNO_01896 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPDMPPNO_01897 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPDMPPNO_01898 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPDMPPNO_01899 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPDMPPNO_01900 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPDMPPNO_01901 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NPDMPPNO_01902 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPDMPPNO_01903 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPDMPPNO_01904 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPDMPPNO_01905 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPDMPPNO_01906 1.2e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPDMPPNO_01907 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPDMPPNO_01908 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NPDMPPNO_01909 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPDMPPNO_01910 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NPDMPPNO_01911 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPDMPPNO_01912 0.0 XK27_09800 I Acyltransferase
NPDMPPNO_01913 9.7e-36 XK27_09805 S MORN repeat protein
NPDMPPNO_01914 3.2e-77 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPDMPPNO_01915 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPDMPPNO_01916 3.8e-90 adk 2.7.4.3 F topology modulation protein
NPDMPPNO_01918 7e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NPDMPPNO_01919 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPDMPPNO_01920 6.3e-44 yrzL S Belongs to the UPF0297 family
NPDMPPNO_01921 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPDMPPNO_01922 3.2e-44 yrzB S Belongs to the UPF0473 family
NPDMPPNO_01923 1.1e-290 ccs S the current gene model (or a revised gene model) may contain a frame shift
NPDMPPNO_01924 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPDMPPNO_01925 1.7e-13
NPDMPPNO_01926 1.6e-88 XK27_10930 K acetyltransferase
NPDMPPNO_01927 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPDMPPNO_01928 3.6e-123 yaaA S Belongs to the UPF0246 family
NPDMPPNO_01929 9.3e-167 XK27_01785 S cog cog1284
NPDMPPNO_01930 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPDMPPNO_01932 1.6e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPDMPPNO_01933 6.1e-236 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NPDMPPNO_01934 1.5e-219 metE 2.1.1.14 E Methionine synthase
NPDMPPNO_01935 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPDMPPNO_01936 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPDMPPNO_01937 1.7e-68 S TIR domain
NPDMPPNO_01938 1.7e-65
NPDMPPNO_01939 1.1e-156 bepIM 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NPDMPPNO_01940 9.4e-82 2.7.11.1 K nucleotide-binding Protein
NPDMPPNO_01941 1.3e-119
NPDMPPNO_01942 4.5e-07 S Sigma-70, region 4
NPDMPPNO_01943 3.1e-45
NPDMPPNO_01944 5.3e-182 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPDMPPNO_01945 8.2e-41
NPDMPPNO_01946 3.4e-101 S Plasmid replication protein
NPDMPPNO_01947 4.9e-22 S MerR HTH family regulatory protein
NPDMPPNO_01948 1.8e-221 sip L Belongs to the 'phage' integrase family
NPDMPPNO_01949 9.2e-217 KLT Protein tyrosine kinase
NPDMPPNO_01950 3.4e-94 tnp* L An automated process has identified a potential problem with this gene model
NPDMPPNO_01951 8.3e-131 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
NPDMPPNO_01952 6.5e-29 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPDMPPNO_01953 8.4e-60 fruR K transcriptional
NPDMPPNO_01954 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPDMPPNO_01955 7.6e-162 T Diguanylate cyclase
NPDMPPNO_01957 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NPDMPPNO_01958 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
NPDMPPNO_01959 0.0
NPDMPPNO_01964 7e-115 nudL L hydrolase
NPDMPPNO_01965 6.3e-54 K transcriptional regulator, PadR family
NPDMPPNO_01966 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
NPDMPPNO_01967 4.4e-107 S Putative adhesin
NPDMPPNO_01968 7.3e-160 XK27_06930 V domain protein
NPDMPPNO_01969 9.3e-95 XK27_06935 K transcriptional regulator
NPDMPPNO_01970 5.4e-54 ypaA M Membrane
NPDMPPNO_01971 1.9e-10
NPDMPPNO_01972 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPDMPPNO_01973 1.8e-47 veg S Biofilm formation stimulator VEG
NPDMPPNO_01974 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPDMPPNO_01975 2.2e-73 rplI J binds to the 23S rRNA
NPDMPPNO_01976 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPDMPPNO_01977 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPDMPPNO_01978 2.4e-99 yvbG U UPF0056 membrane protein
NPDMPPNO_01979 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPDMPPNO_01980 2.4e-311 S Bacterial membrane protein, YfhO
NPDMPPNO_01981 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
NPDMPPNO_01982 1e-70 lytE M LysM domain protein
NPDMPPNO_01983 5.3e-131 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDMPPNO_01984 4.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDMPPNO_01985 5.3e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPDMPPNO_01986 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPDMPPNO_01987 2e-131 S sequence-specific DNA binding
NPDMPPNO_01988 4.7e-238 ymfH S Peptidase M16
NPDMPPNO_01989 1.1e-231 ymfF S Peptidase M16
NPDMPPNO_01990 3.7e-58 yaaA S S4 domain protein YaaA
NPDMPPNO_01991 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPDMPPNO_01992 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NPDMPPNO_01993 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NPDMPPNO_01994 7.8e-152 yvjA S membrane
NPDMPPNO_01995 1.1e-305 ybiT S abc transporter atp-binding protein
NPDMPPNO_01996 0.0 XK27_10405 S Bacterial membrane protein YfhO
NPDMPPNO_02000 4e-119 yoaK S Protein of unknown function (DUF1275)
NPDMPPNO_02001 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPDMPPNO_02002 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NPDMPPNO_02003 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)