ORF_ID e_value Gene_name EC_number CAZy COGs Description
BFDKIJLE_00001 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFDKIJLE_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BFDKIJLE_00003 1.1e-29 yyzM S Protein conserved in bacteria
BFDKIJLE_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BFDKIJLE_00005 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BFDKIJLE_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFDKIJLE_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BFDKIJLE_00008 3e-60 divIC D Septum formation initiator
BFDKIJLE_00010 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
BFDKIJLE_00011 9.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BFDKIJLE_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BFDKIJLE_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BFDKIJLE_00026 2.6e-10
BFDKIJLE_00032 3.2e-94 mreC M Involved in formation and maintenance of cell shape
BFDKIJLE_00033 1.1e-81 mreD M rod shape-determining protein MreD
BFDKIJLE_00034 1.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
BFDKIJLE_00035 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFDKIJLE_00036 1.1e-217 araT 2.6.1.1 E Aminotransferase
BFDKIJLE_00037 8e-140 recO L Involved in DNA repair and RecF pathway recombination
BFDKIJLE_00038 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BFDKIJLE_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFDKIJLE_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BFDKIJLE_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFDKIJLE_00042 1.1e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BFDKIJLE_00043 5.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BFDKIJLE_00044 1.1e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFDKIJLE_00045 2.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BFDKIJLE_00046 2e-157 S CHAP domain
BFDKIJLE_00047 7.4e-236 purD 6.3.4.13 F Belongs to the GARS family
BFDKIJLE_00048 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFDKIJLE_00049 6.7e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFDKIJLE_00050 3.9e-173 1.1.1.169 H Ketopantoate reductase
BFDKIJLE_00051 5.6e-33
BFDKIJLE_00053 6.7e-83
BFDKIJLE_00054 3.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFDKIJLE_00056 4.6e-35 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFDKIJLE_00057 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BFDKIJLE_00058 3.1e-69 argR K Regulates arginine biosynthesis genes
BFDKIJLE_00059 2.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
BFDKIJLE_00060 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFDKIJLE_00061 1.8e-78 S Protein of unknown function (DUF3021)
BFDKIJLE_00062 7.1e-69 K LytTr DNA-binding domain
BFDKIJLE_00064 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFDKIJLE_00066 6.6e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BFDKIJLE_00067 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
BFDKIJLE_00068 1.2e-228 cinA 3.5.1.42 S Belongs to the CinA family
BFDKIJLE_00069 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFDKIJLE_00070 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
BFDKIJLE_00076 2.6e-10
BFDKIJLE_00079 1.9e-07
BFDKIJLE_00084 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFDKIJLE_00085 6.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
BFDKIJLE_00086 5.5e-36 XK27_02060 S Transglycosylase associated protein
BFDKIJLE_00087 2.6e-71 badR K Transcriptional regulator, marr family
BFDKIJLE_00088 3.2e-95 S reductase
BFDKIJLE_00090 1.3e-282 ahpF O alkyl hydroperoxide reductase
BFDKIJLE_00091 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
BFDKIJLE_00092 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
BFDKIJLE_00093 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFDKIJLE_00094 1.6e-82 S Putative small multi-drug export protein
BFDKIJLE_00095 1.8e-75 ctsR K Belongs to the CtsR family
BFDKIJLE_00096 0.0 clpC O Belongs to the ClpA ClpB family
BFDKIJLE_00097 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BFDKIJLE_00098 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BFDKIJLE_00099 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BFDKIJLE_00100 4.7e-140 S SseB protein N-terminal domain
BFDKIJLE_00101 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
BFDKIJLE_00103 4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BFDKIJLE_00104 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BFDKIJLE_00106 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFDKIJLE_00107 1.3e-90 yacP S RNA-binding protein containing a PIN domain
BFDKIJLE_00108 3.8e-151 degV S DegV family
BFDKIJLE_00110 5.1e-22 K Transcriptional
BFDKIJLE_00111 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFDKIJLE_00112 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
BFDKIJLE_00113 1.9e-220 int L Belongs to the 'phage' integrase family
BFDKIJLE_00114 8.1e-39 S Helix-turn-helix domain
BFDKIJLE_00115 1.5e-168 isp2 S CHAP domain
BFDKIJLE_00116 4.4e-30
BFDKIJLE_00117 1.2e-258
BFDKIJLE_00118 0.0 yddE S AAA-like domain
BFDKIJLE_00119 1.6e-70 S TcpE family
BFDKIJLE_00120 3.2e-33
BFDKIJLE_00121 1.1e-157 S Conjugative transposon protein TcpC
BFDKIJLE_00122 1.8e-88
BFDKIJLE_00123 2.5e-33
BFDKIJLE_00124 3.2e-223 K Replication initiation factor
BFDKIJLE_00125 8.2e-218 L Belongs to the 'phage' integrase family
BFDKIJLE_00126 4.5e-10 S Domain of unknown function (DUF3173)
BFDKIJLE_00127 2.6e-87 L Replication initiation factor
BFDKIJLE_00129 9.3e-12 K Transcriptional
BFDKIJLE_00130 8.4e-114 K Psort location Cytoplasmic, score
BFDKIJLE_00131 1.6e-273 ydcQ D Ftsk spoiiie family protein
BFDKIJLE_00132 1e-73
BFDKIJLE_00133 1.3e-42
BFDKIJLE_00134 1.9e-40 K Helix-turn-helix XRE-family like proteins
BFDKIJLE_00136 2.3e-127 E IrrE N-terminal-like domain
BFDKIJLE_00137 7.6e-110 K Peptidase S24-like protein
BFDKIJLE_00138 2.1e-79
BFDKIJLE_00139 8.2e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFDKIJLE_00140 1.9e-27 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFDKIJLE_00141 5e-29
BFDKIJLE_00142 6.1e-32
BFDKIJLE_00143 4.3e-19 K Transcriptional
BFDKIJLE_00144 3.1e-90
BFDKIJLE_00145 1.3e-112 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
BFDKIJLE_00147 3.4e-19
BFDKIJLE_00148 2.5e-18 D nuclear chromosome segregation
BFDKIJLE_00150 1.2e-101 cadD P cadmium resistance
BFDKIJLE_00151 4.5e-55 cadC K Bacterial regulatory protein, arsR family
BFDKIJLE_00152 2.5e-104 yiiE S protein homotetramerization
BFDKIJLE_00153 1.8e-19
BFDKIJLE_00154 4.5e-29 K Helix-turn-helix domain
BFDKIJLE_00156 8.6e-148 srtB 3.4.22.70 S Sortase family
BFDKIJLE_00157 5.7e-233 capA M Bacterial capsule synthesis protein
BFDKIJLE_00158 8e-39 gcvR T UPF0237 protein
BFDKIJLE_00159 2.8e-241 XK27_08635 S UPF0210 protein
BFDKIJLE_00160 1.2e-131 ais G Phosphoglycerate mutase
BFDKIJLE_00161 1e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
BFDKIJLE_00162 3.6e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
BFDKIJLE_00163 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BFDKIJLE_00164 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFDKIJLE_00165 2.3e-302 dnaK O Heat shock 70 kDa protein
BFDKIJLE_00166 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BFDKIJLE_00167 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BFDKIJLE_00168 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
BFDKIJLE_00169 7.4e-80 hmpT S cog cog4720
BFDKIJLE_00182 1.9e-86 sigH K DNA-templated transcription, initiation
BFDKIJLE_00183 2.5e-136 ykuT M mechanosensitive ion channel
BFDKIJLE_00184 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BFDKIJLE_00185 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BFDKIJLE_00186 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BFDKIJLE_00187 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
BFDKIJLE_00188 2.1e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
BFDKIJLE_00189 9.4e-175 prmA J Ribosomal protein L11 methyltransferase
BFDKIJLE_00190 3.4e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BFDKIJLE_00191 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BFDKIJLE_00192 9.1e-83 nrdI F Belongs to the NrdI family
BFDKIJLE_00193 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFDKIJLE_00194 5.7e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BFDKIJLE_00195 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BFDKIJLE_00196 1.9e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFDKIJLE_00197 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BFDKIJLE_00198 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
BFDKIJLE_00199 5.6e-190 yhjX P Major Facilitator
BFDKIJLE_00200 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFDKIJLE_00201 7.1e-72 V VanZ like family
BFDKIJLE_00202 2.6e-179 D nuclear chromosome segregation
BFDKIJLE_00203 5e-123 glnQ E abc transporter atp-binding protein
BFDKIJLE_00204 1.9e-270 glnP P ABC transporter
BFDKIJLE_00205 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BFDKIJLE_00206 2.4e-17 S Protein of unknown function (DUF3021)
BFDKIJLE_00207 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BFDKIJLE_00208 8.7e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
BFDKIJLE_00209 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BFDKIJLE_00210 2e-233 sufD O assembly protein SufD
BFDKIJLE_00211 3.8e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFDKIJLE_00212 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
BFDKIJLE_00213 2.9e-273 sufB O assembly protein SufB
BFDKIJLE_00214 1.6e-26
BFDKIJLE_00215 8e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFDKIJLE_00216 1.1e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFDKIJLE_00217 1.6e-71 adcR K transcriptional
BFDKIJLE_00218 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
BFDKIJLE_00219 5.1e-129 adcB P ABC transporter (Permease
BFDKIJLE_00220 2.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
BFDKIJLE_00221 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BFDKIJLE_00222 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
BFDKIJLE_00223 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
BFDKIJLE_00224 3.5e-152 Z012_04635 K sequence-specific DNA binding
BFDKIJLE_00225 2e-278 V ABC transporter
BFDKIJLE_00226 6.1e-126 yeeN K transcriptional regulatory protein
BFDKIJLE_00227 5.9e-47 yajC U protein transport
BFDKIJLE_00228 2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFDKIJLE_00229 7.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
BFDKIJLE_00230 6.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BFDKIJLE_00231 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BFDKIJLE_00232 0.0 WQ51_06230 S ABC transporter
BFDKIJLE_00233 1.4e-142 cmpC S abc transporter atp-binding protein
BFDKIJLE_00234 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFDKIJLE_00235 1.5e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BFDKIJLE_00237 7.2e-44
BFDKIJLE_00238 1.4e-53 S TM2 domain
BFDKIJLE_00239 5.2e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BFDKIJLE_00240 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BFDKIJLE_00241 1.4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BFDKIJLE_00242 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
BFDKIJLE_00243 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
BFDKIJLE_00244 1.3e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
BFDKIJLE_00245 2.8e-144 cof S Sucrose-6F-phosphate phosphohydrolase
BFDKIJLE_00246 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BFDKIJLE_00247 1e-73 K transcriptional
BFDKIJLE_00248 1.6e-233 S COG1073 Hydrolases of the alpha beta superfamily
BFDKIJLE_00249 1.2e-38 yjdF S Protein of unknown function (DUF2992)
BFDKIJLE_00250 2e-152 cylA V abc transporter atp-binding protein
BFDKIJLE_00251 3.2e-126 cylB V ABC-2 type transporter
BFDKIJLE_00252 9e-75 K COG3279 Response regulator of the LytR AlgR family
BFDKIJLE_00253 7.6e-31 S Protein of unknown function (DUF3021)
BFDKIJLE_00254 7.4e-124 mta K Transcriptional
BFDKIJLE_00255 3.3e-121 yhcA V abc transporter atp-binding protein
BFDKIJLE_00256 2.6e-215 macB_2 V FtsX-like permease family
BFDKIJLE_00257 1.3e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BFDKIJLE_00258 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BFDKIJLE_00259 1.6e-71 yhaI S Protein of unknown function (DUF805)
BFDKIJLE_00260 2.6e-255 pepC 3.4.22.40 E aminopeptidase
BFDKIJLE_00261 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BFDKIJLE_00262 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BFDKIJLE_00263 4e-95 ypsA S Belongs to the UPF0398 family
BFDKIJLE_00264 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BFDKIJLE_00265 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BFDKIJLE_00266 2.4e-281 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
BFDKIJLE_00267 3.7e-87 L COG1943 Transposase and inactivated derivatives
BFDKIJLE_00268 3.2e-145 L Integrase core domain protein
BFDKIJLE_00269 1.6e-123 L Helix-turn-helix domain
BFDKIJLE_00270 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
BFDKIJLE_00271 9.6e-23
BFDKIJLE_00272 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BFDKIJLE_00273 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
BFDKIJLE_00274 4.8e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFDKIJLE_00275 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BFDKIJLE_00276 1.7e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BFDKIJLE_00277 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BFDKIJLE_00278 1.5e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFDKIJLE_00279 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
BFDKIJLE_00280 2.2e-101 ybhL S Belongs to the BI1 family
BFDKIJLE_00281 5.5e-12 ycdA S Domain of unknown function (DUF4352)
BFDKIJLE_00282 9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BFDKIJLE_00283 1.8e-90 K transcriptional regulator
BFDKIJLE_00284 1.6e-36 yneF S UPF0154 protein
BFDKIJLE_00285 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BFDKIJLE_00286 1.9e-183 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFDKIJLE_00287 3.9e-98 XK27_09740 S Phosphoesterase
BFDKIJLE_00288 1.2e-85 ykuL S CBS domain
BFDKIJLE_00289 4.2e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
BFDKIJLE_00290 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BFDKIJLE_00291 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFDKIJLE_00292 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BFDKIJLE_00293 5.1e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
BFDKIJLE_00294 2.7e-258 trkH P Cation transport protein
BFDKIJLE_00295 2.2e-246 trkA P Potassium transporter peripheral membrane component
BFDKIJLE_00296 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BFDKIJLE_00297 5.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BFDKIJLE_00298 1.1e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
BFDKIJLE_00299 7.1e-156 K sequence-specific DNA binding
BFDKIJLE_00300 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BFDKIJLE_00301 3.2e-53 yhaI L Membrane
BFDKIJLE_00302 3.4e-242 S Domain of unknown function (DUF4173)
BFDKIJLE_00303 6.8e-95 ureI S AmiS/UreI family transporter
BFDKIJLE_00304 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
BFDKIJLE_00305 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
BFDKIJLE_00306 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BFDKIJLE_00307 6.6e-78 ureE O enzyme active site formation
BFDKIJLE_00308 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BFDKIJLE_00309 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFDKIJLE_00310 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BFDKIJLE_00311 1.3e-176 cbiM P biosynthesis protein CbiM
BFDKIJLE_00312 2e-135 P cobalt transport protein
BFDKIJLE_00313 6.3e-131 cbiO P ABC transporter
BFDKIJLE_00314 1.4e-137 ET ABC transporter substrate-binding protein
BFDKIJLE_00315 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
BFDKIJLE_00316 5.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BFDKIJLE_00317 3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFDKIJLE_00318 1.2e-99 metI P ABC transporter (Permease
BFDKIJLE_00319 1.9e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BFDKIJLE_00320 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
BFDKIJLE_00321 3e-93 S UPF0397 protein
BFDKIJLE_00322 3.5e-310 ykoD P abc transporter atp-binding protein
BFDKIJLE_00323 4.5e-149 cbiQ P cobalt transport
BFDKIJLE_00324 1.8e-119 ktrA P COG0569 K transport systems, NAD-binding component
BFDKIJLE_00325 4.7e-236 P COG0168 Trk-type K transport systems, membrane components
BFDKIJLE_00326 2.1e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
BFDKIJLE_00327 1.5e-89 yceD K metal-binding, possibly nucleic acid-binding protein
BFDKIJLE_00328 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BFDKIJLE_00329 9.5e-278 T PhoQ Sensor
BFDKIJLE_00330 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFDKIJLE_00331 1.7e-213 dnaB L Replication initiation and membrane attachment
BFDKIJLE_00332 4.4e-166 dnaI L Primosomal protein DnaI
BFDKIJLE_00333 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BFDKIJLE_00334 4.8e-111
BFDKIJLE_00335 5.7e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFDKIJLE_00336 5.5e-62 manO S protein conserved in bacteria
BFDKIJLE_00337 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
BFDKIJLE_00338 7.7e-117 manM G pts system
BFDKIJLE_00339 4.9e-174 manL 2.7.1.191 G pts system
BFDKIJLE_00340 2.2e-66 manO S Protein conserved in bacteria
BFDKIJLE_00341 1.4e-159 manN G PTS system mannose fructose sorbose family IID component
BFDKIJLE_00342 4.7e-135 manY G pts system
BFDKIJLE_00343 6.2e-169 manL 2.7.1.191 G pts system
BFDKIJLE_00344 7.8e-114 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
BFDKIJLE_00345 1.3e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
BFDKIJLE_00346 1.6e-247 pbuO S permease
BFDKIJLE_00347 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
BFDKIJLE_00348 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
BFDKIJLE_00349 9.8e-188 brpA K Transcriptional
BFDKIJLE_00350 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
BFDKIJLE_00351 4e-199 nusA K Participates in both transcription termination and antitermination
BFDKIJLE_00352 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
BFDKIJLE_00353 8e-42 ylxQ J ribosomal protein
BFDKIJLE_00354 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFDKIJLE_00355 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFDKIJLE_00356 5e-99 yvdD 3.2.2.10 S Belongs to the LOG family
BFDKIJLE_00357 1.9e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
BFDKIJLE_00358 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFDKIJLE_00359 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
BFDKIJLE_00360 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
BFDKIJLE_00361 1.7e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
BFDKIJLE_00362 2.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BFDKIJLE_00363 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
BFDKIJLE_00364 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
BFDKIJLE_00365 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFDKIJLE_00366 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BFDKIJLE_00367 6.4e-73 ylbF S Belongs to the UPF0342 family
BFDKIJLE_00368 1.9e-46 ylbG S UPF0298 protein
BFDKIJLE_00369 3.5e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
BFDKIJLE_00370 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
BFDKIJLE_00371 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
BFDKIJLE_00372 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
BFDKIJLE_00373 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
BFDKIJLE_00374 2.5e-110 acuB S CBS domain
BFDKIJLE_00375 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BFDKIJLE_00376 2.2e-108 yvyE 3.4.13.9 S YigZ family
BFDKIJLE_00377 2.4e-237 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BFDKIJLE_00378 1.3e-98 comFC K competence protein
BFDKIJLE_00379 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BFDKIJLE_00387 3.4e-161 ppaC 3.6.1.1 C inorganic pyrophosphatase
BFDKIJLE_00388 2e-101 S Domain of unknown function (DUF1803)
BFDKIJLE_00389 7.8e-102 ygaC J Belongs to the UPF0374 family
BFDKIJLE_00390 1.6e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
BFDKIJLE_00391 1.3e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFDKIJLE_00392 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
BFDKIJLE_00393 1.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
BFDKIJLE_00394 3.5e-117 S HAD hydrolase, family IA, variant 3
BFDKIJLE_00395 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
BFDKIJLE_00396 5.2e-72 marR K Transcriptional regulator, MarR family
BFDKIJLE_00397 1.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFDKIJLE_00398 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFDKIJLE_00399 4.4e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
BFDKIJLE_00400 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
BFDKIJLE_00401 6.2e-126 IQ reductase
BFDKIJLE_00402 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BFDKIJLE_00403 5.2e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BFDKIJLE_00404 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BFDKIJLE_00405 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BFDKIJLE_00406 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFDKIJLE_00407 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BFDKIJLE_00408 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BFDKIJLE_00409 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
BFDKIJLE_00410 1.4e-112 fruR K transcriptional
BFDKIJLE_00411 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BFDKIJLE_00412 0.0 fruA 2.7.1.202 G phosphotransferase system
BFDKIJLE_00413 3.1e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFDKIJLE_00414 1.3e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BFDKIJLE_00416 2e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
BFDKIJLE_00417 2.2e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFDKIJLE_00418 2.3e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BFDKIJLE_00419 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BFDKIJLE_00420 3.6e-83 2.3.1.128 K acetyltransferase
BFDKIJLE_00421 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BFDKIJLE_00422 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BFDKIJLE_00423 6.7e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFDKIJLE_00424 5e-63 WQ51_03320 S cog cog4835
BFDKIJLE_00425 2.8e-146 XK27_08360 S EDD domain protein, DegV family
BFDKIJLE_00426 5.7e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BFDKIJLE_00427 3.2e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BFDKIJLE_00428 0.0 yfmR S abc transporter atp-binding protein
BFDKIJLE_00429 1.7e-26 U response to pH
BFDKIJLE_00430 5.3e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
BFDKIJLE_00431 5.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
BFDKIJLE_00432 2.6e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
BFDKIJLE_00433 6.2e-283 S Psort location CytoplasmicMembrane, score
BFDKIJLE_00434 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BFDKIJLE_00435 1.7e-73 K DNA-binding transcription factor activity
BFDKIJLE_00436 2.5e-311 lmrA1 V abc transporter atp-binding protein
BFDKIJLE_00437 0.0 lmrA2 V abc transporter atp-binding protein
BFDKIJLE_00438 4.3e-112 K Acetyltransferase (GNAT) family
BFDKIJLE_00439 5.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
BFDKIJLE_00440 8.3e-117 T response regulator
BFDKIJLE_00441 1.2e-214 sptS 2.7.13.3 T Histidine kinase
BFDKIJLE_00442 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BFDKIJLE_00443 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BFDKIJLE_00444 4.5e-160 cvfB S Protein conserved in bacteria
BFDKIJLE_00445 3.7e-34 yozE S Belongs to the UPF0346 family
BFDKIJLE_00446 1.3e-123 sip M LysM domain protein
BFDKIJLE_00447 5.2e-190 phoH T phosphate starvation-inducible protein PhoH
BFDKIJLE_00451 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFDKIJLE_00452 9e-161 S reductase
BFDKIJLE_00453 4.7e-168 K transcriptional regulator (lysR family)
BFDKIJLE_00454 2.2e-107 S CAAX amino terminal protease family protein
BFDKIJLE_00455 1.2e-274 S Glucan-binding protein C
BFDKIJLE_00456 2.6e-172 coiA 3.6.4.12 S Competence protein
BFDKIJLE_00457 0.0 pepF E oligoendopeptidase F
BFDKIJLE_00458 4.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
BFDKIJLE_00459 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
BFDKIJLE_00460 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
BFDKIJLE_00461 7.1e-86 yxjI S LURP-one-related
BFDKIJLE_00462 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFDKIJLE_00463 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BFDKIJLE_00464 8.3e-134 agrA KT response regulator
BFDKIJLE_00466 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
BFDKIJLE_00467 4.4e-138 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BFDKIJLE_00468 9.7e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
BFDKIJLE_00469 5.9e-183 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFDKIJLE_00470 1.9e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BFDKIJLE_00471 1.1e-122 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
BFDKIJLE_00472 1.3e-207 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BFDKIJLE_00473 6.7e-135 yxkH G deacetylase
BFDKIJLE_00474 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BFDKIJLE_00475 9.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BFDKIJLE_00476 2.6e-150 rarD S Transporter
BFDKIJLE_00477 2.2e-15 T peptidase
BFDKIJLE_00478 3e-14 coiA 3.6.4.12 S Competence protein
BFDKIJLE_00479 1.1e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BFDKIJLE_00480 2.7e-97 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BFDKIJLE_00481 7.4e-19
BFDKIJLE_00483 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BFDKIJLE_00485 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFDKIJLE_00486 7.6e-121 atpB C it plays a direct role in the translocation of protons across the membrane
BFDKIJLE_00487 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFDKIJLE_00488 3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFDKIJLE_00489 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFDKIJLE_00490 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFDKIJLE_00491 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFDKIJLE_00492 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BFDKIJLE_00493 2.1e-217 ftsW D Belongs to the SEDS family
BFDKIJLE_00494 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFDKIJLE_00495 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BFDKIJLE_00496 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFDKIJLE_00498 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFDKIJLE_00499 4.3e-158 holB 2.7.7.7 L dna polymerase iii
BFDKIJLE_00500 6.4e-132 yaaT S stage 0 sporulation protein
BFDKIJLE_00501 1.2e-54 yabA L Involved in initiation control of chromosome replication
BFDKIJLE_00502 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BFDKIJLE_00503 1.6e-227 amt P Ammonium Transporter
BFDKIJLE_00504 9.5e-53 glnB K Belongs to the P(II) protein family
BFDKIJLE_00505 7.8e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
BFDKIJLE_00506 1.1e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
BFDKIJLE_00507 1.8e-82 S Bacterial inner membrane protein
BFDKIJLE_00508 8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
BFDKIJLE_00509 7.2e-292 nptA P COG1283 Na phosphate symporter
BFDKIJLE_00510 1e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFDKIJLE_00511 4.8e-219 S membrane
BFDKIJLE_00512 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BFDKIJLE_00513 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BFDKIJLE_00514 1.7e-38 ynzC S UPF0291 protein
BFDKIJLE_00515 4e-251 cycA E permease
BFDKIJLE_00516 1.9e-09 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFDKIJLE_00517 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BFDKIJLE_00518 3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFDKIJLE_00519 4.3e-08 KLT serine threonine protein kinase
BFDKIJLE_00522 1.1e-67 K Helix-turn-helix
BFDKIJLE_00524 1.1e-167 fhuR K transcriptional regulator (lysR family)
BFDKIJLE_00525 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFDKIJLE_00526 4.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BFDKIJLE_00527 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BFDKIJLE_00528 1.8e-221 pyrP F uracil Permease
BFDKIJLE_00529 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BFDKIJLE_00530 6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
BFDKIJLE_00531 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
BFDKIJLE_00532 5.8e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
BFDKIJLE_00533 4.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFDKIJLE_00534 6.4e-120 macB V ABC transporter, ATP-binding protein
BFDKIJLE_00535 8.2e-200 V permease protein
BFDKIJLE_00536 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFDKIJLE_00537 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BFDKIJLE_00539 1.7e-27 M Plasmid recombination enzyme
BFDKIJLE_00541 3.9e-232 2.7.13.3 T GHKL domain
BFDKIJLE_00542 6.9e-133 agrA KT Response regulator of the LytR AlgR family
BFDKIJLE_00544 2.6e-85 L COG1943 Transposase and inactivated derivatives
BFDKIJLE_00545 4.9e-71 2.7.13.3 T Histidine kinase
BFDKIJLE_00546 8.8e-111 K Transcriptional regulatory protein, C terminal
BFDKIJLE_00548 1.9e-48 6.3.5.4 E Asparagine synthase
BFDKIJLE_00550 5.1e-24 S Transglutaminase-like superfamily
BFDKIJLE_00551 6.4e-120 V abc transporter atp-binding protein
BFDKIJLE_00552 6.8e-17
BFDKIJLE_00554 3.3e-85 V ABC transporter, ATP-binding protein
BFDKIJLE_00555 9.1e-37 K Helix-turn-helix
BFDKIJLE_00556 3.3e-40 D LPXTG cell wall anchor motif
BFDKIJLE_00558 1.3e-94 amiB 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
BFDKIJLE_00560 4.2e-70
BFDKIJLE_00563 1.5e-16 S Domain of unknown function (DUF3173)
BFDKIJLE_00564 5.9e-147 L Phage integrase SAM-like domain
BFDKIJLE_00565 0.0 mdlB V abc transporter atp-binding protein
BFDKIJLE_00566 0.0 lmrA V abc transporter atp-binding protein
BFDKIJLE_00567 7.8e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFDKIJLE_00568 4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BFDKIJLE_00569 4.5e-196 yceA S Belongs to the UPF0176 family
BFDKIJLE_00570 6.6e-114 S VIT family
BFDKIJLE_00571 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BFDKIJLE_00572 7.7e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BFDKIJLE_00573 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
BFDKIJLE_00575 2.2e-145 E Alpha beta hydrolase
BFDKIJLE_00576 2.8e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFDKIJLE_00577 1.2e-152 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
BFDKIJLE_00578 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BFDKIJLE_00579 3.9e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
BFDKIJLE_00580 2.3e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BFDKIJLE_00581 1.9e-88 L COG1943 Transposase and inactivated derivatives
BFDKIJLE_00582 2.1e-149 V ABC transporter, ATP-binding protein
BFDKIJLE_00583 4.8e-54 S ABC-2 family transporter protein
BFDKIJLE_00584 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
BFDKIJLE_00585 1.1e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFDKIJLE_00586 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
BFDKIJLE_00587 4.6e-23
BFDKIJLE_00588 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFDKIJLE_00589 0.0 U protein secretion
BFDKIJLE_00590 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
BFDKIJLE_00591 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BFDKIJLE_00592 1.1e-12
BFDKIJLE_00593 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFDKIJLE_00594 1.4e-151 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BFDKIJLE_00595 2e-194 S Protein of unknown function (DUF3114)
BFDKIJLE_00596 4.1e-29 pspC KT PspC domain protein
BFDKIJLE_00597 1.3e-117 yqfA K protein, Hemolysin III
BFDKIJLE_00598 3e-78 K hmm pf08876
BFDKIJLE_00599 2.5e-223 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BFDKIJLE_00600 7.4e-214 mvaS 2.3.3.10 I synthase
BFDKIJLE_00601 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFDKIJLE_00602 6.4e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFDKIJLE_00603 9.7e-22
BFDKIJLE_00604 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFDKIJLE_00605 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
BFDKIJLE_00606 8.5e-168 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
BFDKIJLE_00607 2.2e-30 S Domain of unknown function (DUF1912)
BFDKIJLE_00608 1.1e-12 L Helix-hairpin-helix DNA-binding motif class 1
BFDKIJLE_00609 1.6e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BFDKIJLE_00610 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BFDKIJLE_00612 7.4e-12
BFDKIJLE_00613 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BFDKIJLE_00614 1.1e-200 ilvE 2.6.1.42 E Aminotransferase
BFDKIJLE_00615 4.8e-16 S Protein of unknown function (DUF2969)
BFDKIJLE_00618 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
BFDKIJLE_00621 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
BFDKIJLE_00622 4.4e-118 M Pfam SNARE associated Golgi protein
BFDKIJLE_00623 1.7e-229 murN 2.3.2.16 V FemAB family
BFDKIJLE_00624 5.8e-172 S oxidoreductase
BFDKIJLE_00625 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
BFDKIJLE_00626 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
BFDKIJLE_00627 0.0 clpE O Belongs to the ClpA ClpB family
BFDKIJLE_00628 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFDKIJLE_00629 1e-34 ykuJ S protein conserved in bacteria
BFDKIJLE_00630 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
BFDKIJLE_00631 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_00632 3.8e-76 feoA P FeoA domain protein
BFDKIJLE_00633 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BFDKIJLE_00634 6.6e-08
BFDKIJLE_00635 6.1e-148 I Alpha/beta hydrolase family
BFDKIJLE_00636 6.3e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFDKIJLE_00637 5.8e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFDKIJLE_00638 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
BFDKIJLE_00639 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFDKIJLE_00640 4e-145 licT K antiterminator
BFDKIJLE_00641 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFDKIJLE_00642 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BFDKIJLE_00643 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BFDKIJLE_00644 2.9e-148 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BFDKIJLE_00645 2.7e-98 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BFDKIJLE_00646 2.9e-221 mdtG EGP Major facilitator Superfamily
BFDKIJLE_00647 2.6e-33 secG U Preprotein translocase subunit SecG
BFDKIJLE_00648 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BFDKIJLE_00649 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BFDKIJLE_00650 2.4e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFDKIJLE_00651 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
BFDKIJLE_00652 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
BFDKIJLE_00653 2.4e-181 ccpA K Catabolite control protein A
BFDKIJLE_00654 3.6e-199 yyaQ S YjbR
BFDKIJLE_00655 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BFDKIJLE_00656 3.1e-75 yueI S Protein of unknown function (DUF1694)
BFDKIJLE_00657 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BFDKIJLE_00658 4.6e-25 WQ51_00785
BFDKIJLE_00659 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BFDKIJLE_00660 7.1e-217 ywbD 2.1.1.191 J Methyltransferase
BFDKIJLE_00661 5.8e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BFDKIJLE_00662 5.3e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFDKIJLE_00663 5.4e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFDKIJLE_00664 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFDKIJLE_00665 9.2e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BFDKIJLE_00666 4.2e-53 yheA S Belongs to the UPF0342 family
BFDKIJLE_00667 6.5e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BFDKIJLE_00668 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BFDKIJLE_00669 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFDKIJLE_00670 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
BFDKIJLE_00671 8e-247 msrR K Transcriptional regulator
BFDKIJLE_00672 1.2e-150 ydiA P C4-dicarboxylate transporter malic acid transport
BFDKIJLE_00673 8.5e-201 I acyl-CoA dehydrogenase
BFDKIJLE_00674 2.2e-96 mip S hydroperoxide reductase activity
BFDKIJLE_00675 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFDKIJLE_00676 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
BFDKIJLE_00677 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
BFDKIJLE_00678 1.6e-61 smtB K Transcriptional regulator
BFDKIJLE_00679 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
BFDKIJLE_00681 4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BFDKIJLE_00682 6.7e-136 S Domain of unknown function (DUF4336)
BFDKIJLE_00683 8.5e-202 yeaN P transporter
BFDKIJLE_00684 6.4e-151 yitS S EDD domain protein, DegV family
BFDKIJLE_00685 2.6e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
BFDKIJLE_00686 3.3e-98 ypgQ F HD superfamily hydrolase
BFDKIJLE_00687 2.2e-127 S CAAX amino terminal protease family
BFDKIJLE_00688 1.9e-107 cutC P Participates in the control of copper homeostasis
BFDKIJLE_00690 5.4e-21 S Domain of unknown function (DUF4767)
BFDKIJLE_00691 2.3e-148 S Domain of unknown function (DUF4300)
BFDKIJLE_00692 7e-117 V CAAX protease self-immunity
BFDKIJLE_00693 2.3e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFDKIJLE_00694 3.7e-134 fecE 3.6.3.34 HP ABC transporter
BFDKIJLE_00695 8.5e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
BFDKIJLE_00696 3.4e-126 ybbA S Putative esterase
BFDKIJLE_00697 5.7e-158 yegS 2.7.1.107 I Diacylglycerol kinase
BFDKIJLE_00698 2.3e-171 S Domain of unknown function (DUF389)
BFDKIJLE_00699 5.5e-31 S Membrane
BFDKIJLE_00700 2.9e-09 S CsbD-like
BFDKIJLE_00701 1.6e-172 pdhD 1.8.1.4 C Dehydrogenase
BFDKIJLE_00702 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
BFDKIJLE_00703 1.3e-174 acoB C dehydrogenase E1 component
BFDKIJLE_00704 1.2e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BFDKIJLE_00705 2.2e-48
BFDKIJLE_00706 7e-125 V CAAX protease self-immunity
BFDKIJLE_00707 8.3e-09
BFDKIJLE_00708 5.3e-21 M Bacterial lipoprotein
BFDKIJLE_00709 1.7e-61 S Protein of unknown function (DUF1722)
BFDKIJLE_00710 3.7e-63 yqeB S Pyrimidine dimer DNA glycosylase
BFDKIJLE_00712 5.5e-51
BFDKIJLE_00713 4.4e-93 S CAAX protease self-immunity
BFDKIJLE_00714 2.5e-115 estA E GDSL-like Lipase/Acylhydrolase
BFDKIJLE_00715 7.3e-104
BFDKIJLE_00716 2.3e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
BFDKIJLE_00717 9.9e-149 ycgQ S TIGR03943 family
BFDKIJLE_00718 1.9e-156 XK27_03015 S permease
BFDKIJLE_00720 0.0 yhgF K Transcriptional accessory protein
BFDKIJLE_00721 6.4e-41 pspC KT PspC domain
BFDKIJLE_00722 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BFDKIJLE_00723 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFDKIJLE_00724 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BFDKIJLE_00725 3e-67 ytxH S General stress protein
BFDKIJLE_00727 2.6e-177 yegQ O Peptidase U32
BFDKIJLE_00728 1.7e-251 yegQ O Peptidase U32
BFDKIJLE_00729 1.1e-87 bioY S biotin synthase
BFDKIJLE_00731 1.1e-33 XK27_12190 S protein conserved in bacteria
BFDKIJLE_00732 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
BFDKIJLE_00733 1.9e-12
BFDKIJLE_00734 3e-12
BFDKIJLE_00735 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BFDKIJLE_00736 4.8e-137 M LysM domain
BFDKIJLE_00737 8.4e-23
BFDKIJLE_00738 5.2e-175 S hydrolase
BFDKIJLE_00740 3.6e-114 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
BFDKIJLE_00741 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFDKIJLE_00742 7.9e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
BFDKIJLE_00743 1.3e-26 P Hemerythrin HHE cation binding domain protein
BFDKIJLE_00744 3.5e-157 5.2.1.8 G hydrolase
BFDKIJLE_00745 3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFDKIJLE_00746 6.4e-210 MA20_36090 S Protein of unknown function (DUF2974)
BFDKIJLE_00747 2.6e-130 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BFDKIJLE_00749 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
BFDKIJLE_00750 3.6e-165 S Bacteriophage abortive infection AbiH
BFDKIJLE_00752 3.8e-130 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
BFDKIJLE_00753 2.2e-152 E Psort location Cytoplasmic, score
BFDKIJLE_00754 8e-56 S Phage derived protein Gp49-like (DUF891)
BFDKIJLE_00755 1e-42 K Helix-turn-helix domain
BFDKIJLE_00756 1.8e-303 hsdM 2.1.1.72 V type I restriction-modification system
BFDKIJLE_00757 2.5e-135 S double-stranded DNA endodeoxyribonuclease activity
BFDKIJLE_00758 0.0 2.4.1.21 GT5 M Right handed beta helix region
BFDKIJLE_00759 2.2e-174 spd F DNA RNA non-specific endonuclease
BFDKIJLE_00760 7.7e-92 lemA S LemA family
BFDKIJLE_00761 1.7e-133 htpX O Belongs to the peptidase M48B family
BFDKIJLE_00762 9.1e-113 sirR K iron dependent repressor
BFDKIJLE_00763 1.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
BFDKIJLE_00764 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
BFDKIJLE_00765 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
BFDKIJLE_00766 2.1e-74 S Psort location CytoplasmicMembrane, score
BFDKIJLE_00767 2.1e-64 S Domain of unknown function (DUF4430)
BFDKIJLE_00768 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFDKIJLE_00769 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
BFDKIJLE_00770 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
BFDKIJLE_00771 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
BFDKIJLE_00772 8.3e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
BFDKIJLE_00773 1.1e-89 dps P Belongs to the Dps family
BFDKIJLE_00774 3.4e-79 perR P Belongs to the Fur family
BFDKIJLE_00775 9.7e-30 yqgQ S protein conserved in bacteria
BFDKIJLE_00776 2.7e-177 glk 2.7.1.2 G Glucokinase
BFDKIJLE_00777 0.0 typA T GTP-binding protein TypA
BFDKIJLE_00779 1.9e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFDKIJLE_00780 4.7e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFDKIJLE_00781 2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BFDKIJLE_00782 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BFDKIJLE_00783 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFDKIJLE_00784 3.6e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFDKIJLE_00785 1.8e-99 sepF D cell septum assembly
BFDKIJLE_00786 1.7e-30 yggT D integral membrane protein
BFDKIJLE_00787 1.2e-138 ylmH S conserved protein, contains S4-like domain
BFDKIJLE_00788 8.4e-138 divIVA D Cell division initiation protein
BFDKIJLE_00789 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFDKIJLE_00790 1.6e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFDKIJLE_00791 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFDKIJLE_00792 6.5e-34 nrdH O Glutaredoxin
BFDKIJLE_00793 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BFDKIJLE_00794 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
BFDKIJLE_00795 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
BFDKIJLE_00796 3e-38 ptsH G phosphocarrier protein Hpr
BFDKIJLE_00797 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BFDKIJLE_00798 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
BFDKIJLE_00799 6.1e-162 XK27_05670 S Putative esterase
BFDKIJLE_00800 2.7e-153 XK27_05675 S Esterase
BFDKIJLE_00801 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
BFDKIJLE_00802 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
BFDKIJLE_00803 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
BFDKIJLE_00804 0.0 uup S abc transporter atp-binding protein
BFDKIJLE_00805 1.6e-39 MA20_06245 S yiaA/B two helix domain
BFDKIJLE_00806 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
BFDKIJLE_00807 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BFDKIJLE_00808 2.3e-150 cobQ S glutamine amidotransferase
BFDKIJLE_00809 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
BFDKIJLE_00810 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BFDKIJLE_00811 3.8e-163 ybbR S Protein conserved in bacteria
BFDKIJLE_00812 4.8e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFDKIJLE_00813 1.3e-64 gtrA S GtrA-like protein
BFDKIJLE_00814 8.1e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
BFDKIJLE_00815 1.9e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFDKIJLE_00816 4.4e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
BFDKIJLE_00817 8.7e-201 yurR 1.4.5.1 E oxidoreductase
BFDKIJLE_00818 2.8e-257 S phospholipase Carboxylesterase
BFDKIJLE_00819 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFDKIJLE_00820 4.6e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BFDKIJLE_00821 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BFDKIJLE_00823 8.4e-30 KT response to antibiotic
BFDKIJLE_00824 3.8e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
BFDKIJLE_00825 9.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
BFDKIJLE_00826 1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BFDKIJLE_00827 1.5e-115 ylfI S tigr01906
BFDKIJLE_00828 3.2e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
BFDKIJLE_00829 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
BFDKIJLE_00830 7.5e-62 XK27_08085
BFDKIJLE_00831 7.9e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFDKIJLE_00832 6.5e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BFDKIJLE_00833 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BFDKIJLE_00834 1.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFDKIJLE_00835 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
BFDKIJLE_00836 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFDKIJLE_00837 2.9e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFDKIJLE_00838 2.4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BFDKIJLE_00839 2.3e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFDKIJLE_00840 6.9e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
BFDKIJLE_00842 1.9e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
BFDKIJLE_00843 5.4e-144 P molecular chaperone
BFDKIJLE_00844 3.6e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
BFDKIJLE_00845 3e-179 XK27_08075 M glycosyl transferase family 2
BFDKIJLE_00846 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_00847 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_00848 1.7e-100 L COG3547 Transposase and inactivated derivatives
BFDKIJLE_00849 4.1e-57 L transposase IS116 IS110 IS902 family
BFDKIJLE_00850 1.5e-14 L COG3547 Transposase and inactivated derivatives
BFDKIJLE_00851 2e-42 mccF V LD-carboxypeptidase
BFDKIJLE_00852 1.3e-163 L High confidence in function and specificity
BFDKIJLE_00853 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_00854 2.4e-235 rodA D Belongs to the SEDS family
BFDKIJLE_00855 9.2e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFDKIJLE_00856 3.4e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BFDKIJLE_00857 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BFDKIJLE_00858 2.4e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BFDKIJLE_00859 2.3e-22 Q Methyltransferase domain
BFDKIJLE_00860 2.3e-66 GnaT 2.5.1.16 K acetyltransferase
BFDKIJLE_00861 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
BFDKIJLE_00862 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFDKIJLE_00863 1.1e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFDKIJLE_00864 6.5e-125 dnaD
BFDKIJLE_00865 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFDKIJLE_00867 2.8e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BFDKIJLE_00868 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BFDKIJLE_00869 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BFDKIJLE_00870 7.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BFDKIJLE_00871 8.3e-73 argR K Regulates arginine biosynthesis genes
BFDKIJLE_00872 4.6e-302 recN L May be involved in recombinational repair of damaged DNA
BFDKIJLE_00873 5.6e-147 DegV S DegV family
BFDKIJLE_00874 6.9e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
BFDKIJLE_00875 1.7e-94 ypmS S Protein conserved in bacteria
BFDKIJLE_00876 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BFDKIJLE_00878 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
BFDKIJLE_00879 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFDKIJLE_00880 2.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFDKIJLE_00881 1.9e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BFDKIJLE_00882 3.5e-37 ysdA L Membrane
BFDKIJLE_00883 4.9e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFDKIJLE_00884 1e-110 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFDKIJLE_00885 2.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
BFDKIJLE_00886 0.0 dnaE 2.7.7.7 L DNA polymerase
BFDKIJLE_00887 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BFDKIJLE_00888 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BFDKIJLE_00889 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_00890 5.9e-217 L the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_00891 1.3e-18 S Domain of unknown function (DUF4649)
BFDKIJLE_00892 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
BFDKIJLE_00893 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
BFDKIJLE_00894 7.6e-135 XK27_08845 S abc transporter atp-binding protein
BFDKIJLE_00895 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BFDKIJLE_00896 9.5e-149 estA CE1 S Esterase
BFDKIJLE_00897 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
BFDKIJLE_00898 2.8e-18 XK27_08880
BFDKIJLE_00899 1e-75 fld C Flavodoxin
BFDKIJLE_00900 2.4e-281 clcA P Chloride transporter, ClC family
BFDKIJLE_00901 2.1e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
BFDKIJLE_00902 5e-213 XK27_05110 P Chloride transporter ClC family
BFDKIJLE_00903 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BFDKIJLE_00906 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
BFDKIJLE_00907 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFDKIJLE_00908 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
BFDKIJLE_00909 5.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BFDKIJLE_00910 7.3e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BFDKIJLE_00911 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BFDKIJLE_00912 5.1e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
BFDKIJLE_00913 8.8e-146
BFDKIJLE_00914 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
BFDKIJLE_00915 3.9e-270 pelF GT4 M Domain of unknown function (DUF3492)
BFDKIJLE_00916 5.8e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
BFDKIJLE_00917 3.8e-222 cotH M CotH kinase protein
BFDKIJLE_00918 3e-96 P VTC domain
BFDKIJLE_00919 9.2e-84 S membrane
BFDKIJLE_00920 3.5e-133 G Domain of unknown function (DUF4832)
BFDKIJLE_00921 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BFDKIJLE_00923 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFDKIJLE_00924 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
BFDKIJLE_00925 2.5e-153 endA F DNA RNA non-specific endonuclease
BFDKIJLE_00926 1.8e-69 tcyB_2 P ABC transporter (permease)
BFDKIJLE_00927 1.4e-40 gltJ P ABC transporter (Permease
BFDKIJLE_00928 2.8e-138 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BFDKIJLE_00929 5.1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_00930 1.2e-68 tcyB_2 P ABC transporter (permease)
BFDKIJLE_00931 1.4e-40 gltJ P ABC transporter (Permease
BFDKIJLE_00932 5.9e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BFDKIJLE_00933 3.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_00934 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BFDKIJLE_00935 3e-235 vicK 2.7.13.3 T Histidine kinase
BFDKIJLE_00936 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
BFDKIJLE_00937 3.9e-57 S Protein of unknown function (DUF454)
BFDKIJLE_00938 5.1e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
BFDKIJLE_00939 1.7e-145 yidA S hydrolases of the HAD superfamily
BFDKIJLE_00940 1.3e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
BFDKIJLE_00941 5.3e-68 ywiB S Domain of unknown function (DUF1934)
BFDKIJLE_00942 0.0 pacL 3.6.3.8 P cation transport ATPase
BFDKIJLE_00943 1.6e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BFDKIJLE_00944 1.1e-155 yjjH S Calcineurin-like phosphoesterase
BFDKIJLE_00945 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BFDKIJLE_00946 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BFDKIJLE_00947 3.2e-124 ftsE D cell division ATP-binding protein FtsE
BFDKIJLE_00948 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BFDKIJLE_00949 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
BFDKIJLE_00950 3.6e-176 yubA S permease
BFDKIJLE_00951 1.5e-220 G COG0457 FOG TPR repeat
BFDKIJLE_00952 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BFDKIJLE_00953 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
BFDKIJLE_00954 2e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BFDKIJLE_00955 1.5e-86 ebsA S Family of unknown function (DUF5322)
BFDKIJLE_00956 2.5e-17 M LysM domain
BFDKIJLE_00957 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BFDKIJLE_00958 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BFDKIJLE_00959 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BFDKIJLE_00960 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFDKIJLE_00961 5.5e-83 XK27_03610 K Gnat family
BFDKIJLE_00962 5.5e-92 yybC
BFDKIJLE_00963 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BFDKIJLE_00964 2.5e-272 pepV 3.5.1.18 E Dipeptidase
BFDKIJLE_00965 1.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
BFDKIJLE_00966 2e-228 V Glucan-binding protein C
BFDKIJLE_00967 3.3e-253 V Glucan-binding protein C
BFDKIJLE_00968 5.9e-217 L the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_00969 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFDKIJLE_00970 6.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFDKIJLE_00971 1.4e-95 S Protein of unknown function (DUF1697)
BFDKIJLE_00972 2.2e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BFDKIJLE_00973 2.8e-171 clcA_2 P Chloride transporter, ClC family
BFDKIJLE_00974 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
BFDKIJLE_00975 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
BFDKIJLE_00976 9.4e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
BFDKIJLE_00977 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
BFDKIJLE_00978 1.7e-109 cps4C M biosynthesis protein
BFDKIJLE_00979 7.7e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
BFDKIJLE_00980 2.1e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
BFDKIJLE_00981 7.2e-217 rgpAc GT4 M group 1 family protein
BFDKIJLE_00982 8.8e-212 wcoF M Glycosyltransferase, group 1 family protein
BFDKIJLE_00983 2.6e-85 Z012_10770 M Domain of unknown function (DUF1919)
BFDKIJLE_00984 2.9e-171 M Glycosyltransferase, group 2 family protein
BFDKIJLE_00985 4.1e-165 M Glycosyltransferase like family 2
BFDKIJLE_00986 1.7e-173
BFDKIJLE_00987 1.8e-243 epsU S Polysaccharide biosynthesis protein
BFDKIJLE_00988 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
BFDKIJLE_00989 3.1e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
BFDKIJLE_00990 1.5e-186 wbbI M transferase activity, transferring glycosyl groups
BFDKIJLE_00992 7.9e-138 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
BFDKIJLE_00993 1.6e-108 pgm G Belongs to the phosphoglycerate mutase family
BFDKIJLE_00994 4.1e-107 G Belongs to the phosphoglycerate mutase family
BFDKIJLE_00995 2.6e-106 G Belongs to the phosphoglycerate mutase family
BFDKIJLE_00996 8.8e-196 S hmm pf01594
BFDKIJLE_00997 1.7e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BFDKIJLE_00998 9.2e-38 S granule-associated protein
BFDKIJLE_00999 8e-280 S unusual protein kinase
BFDKIJLE_01000 5e-100 estA E Lysophospholipase L1 and related esterases
BFDKIJLE_01001 5.3e-153 rssA S Phospholipase, patatin family
BFDKIJLE_01002 2.1e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
BFDKIJLE_01003 8.1e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BFDKIJLE_01004 4.5e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFDKIJLE_01005 3.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BFDKIJLE_01006 3.3e-166 S the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_01007 3.2e-226 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01008 4.2e-207 hpk9 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01009 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
BFDKIJLE_01010 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BFDKIJLE_01011 2.7e-207 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BFDKIJLE_01012 0.0 lpdA 1.8.1.4 C Dehydrogenase
BFDKIJLE_01013 0.0 3.5.1.28 NU amidase activity
BFDKIJLE_01014 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
BFDKIJLE_01015 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BFDKIJLE_01016 1.7e-138 ycdO P periplasmic lipoprotein involved in iron transport
BFDKIJLE_01017 1.8e-231 ycdB P peroxidase
BFDKIJLE_01018 6.8e-285 ywbL P COG0672 High-affinity Fe2 Pb2 permease
BFDKIJLE_01019 4.6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFDKIJLE_01020 3e-24 tatA U protein secretion
BFDKIJLE_01021 4.7e-213 msmX P Belongs to the ABC transporter superfamily
BFDKIJLE_01022 9.8e-152 malG P ABC transporter (Permease
BFDKIJLE_01023 1.4e-248 malF P ABC transporter (Permease
BFDKIJLE_01024 3.9e-229 malX G ABC transporter
BFDKIJLE_01025 1e-179 malR K Transcriptional regulator
BFDKIJLE_01026 1.4e-297 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
BFDKIJLE_01027 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BFDKIJLE_01028 2.2e-27
BFDKIJLE_01029 5.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
BFDKIJLE_01030 4.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
BFDKIJLE_01031 0.0 pepN 3.4.11.2 E aminopeptidase
BFDKIJLE_01032 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
BFDKIJLE_01033 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BFDKIJLE_01034 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BFDKIJLE_01035 1.3e-154 pstA P phosphate transport system permease
BFDKIJLE_01036 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
BFDKIJLE_01037 9e-156 pstS P phosphate
BFDKIJLE_01038 8.5e-251 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BFDKIJLE_01039 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BFDKIJLE_01040 1.5e-43 yktA S Belongs to the UPF0223 family
BFDKIJLE_01041 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BFDKIJLE_01042 1.8e-167 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BFDKIJLE_01043 5.6e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFDKIJLE_01044 1.8e-243 XK27_04775 S hemerythrin HHE cation binding domain
BFDKIJLE_01045 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
BFDKIJLE_01046 4.8e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
BFDKIJLE_01047 3.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BFDKIJLE_01048 4.7e-137 S haloacid dehalogenase-like hydrolase
BFDKIJLE_01049 1.5e-239 metY 2.5.1.49 E o-acetylhomoserine
BFDKIJLE_01050 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BFDKIJLE_01051 2.8e-241 agcS E (Alanine) symporter
BFDKIJLE_01052 2.8e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFDKIJLE_01053 4.6e-171 bglC K Transcriptional regulator
BFDKIJLE_01054 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
BFDKIJLE_01055 6.4e-82 yecS P ABC transporter (Permease
BFDKIJLE_01056 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
BFDKIJLE_01057 6.1e-242 nylA 3.5.1.4 J Belongs to the amidase family
BFDKIJLE_01058 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFDKIJLE_01059 5.9e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BFDKIJLE_01060 1e-147 csm6 S Psort location Cytoplasmic, score
BFDKIJLE_01061 3.9e-114 csm6 S Psort location Cytoplasmic, score
BFDKIJLE_01062 6.4e-204 csm5 L CRISPR-associated RAMP protein, Csm5 family
BFDKIJLE_01063 3.7e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
BFDKIJLE_01064 2.4e-116 csm3 L RAMP superfamily
BFDKIJLE_01065 7.3e-62 csm2 L Pfam:DUF310
BFDKIJLE_01066 0.0 csm1 S CRISPR-associated protein Csm1 family
BFDKIJLE_01067 6e-129 cas6 S Pfam:DUF2276
BFDKIJLE_01068 5.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BFDKIJLE_01069 3.6e-91 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BFDKIJLE_01070 2.1e-80 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BFDKIJLE_01071 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BFDKIJLE_01072 1.5e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BFDKIJLE_01073 9.4e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
BFDKIJLE_01074 1.2e-133 S TraX protein
BFDKIJLE_01075 4.3e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
BFDKIJLE_01076 2.1e-277 S Psort location CytoplasmicMembrane, score
BFDKIJLE_01077 7.6e-88 V ABC transporter, ATP-binding protein
BFDKIJLE_01078 5.5e-47
BFDKIJLE_01079 4.5e-231 dinF V Mate efflux family protein
BFDKIJLE_01080 1.2e-177 yclQ P ABC-type enterochelin transport system, periplasmic component
BFDKIJLE_01081 0.0 V Type III restriction enzyme, res subunit
BFDKIJLE_01082 2.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
BFDKIJLE_01083 3e-139 2.4.2.3 F Phosphorylase superfamily
BFDKIJLE_01085 0.0 spxB 1.2.3.3, 1.2.5.1 C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
BFDKIJLE_01086 0.0 copA 3.6.3.54 P P-type ATPase
BFDKIJLE_01087 4e-65 silP 1.9.3.1, 3.6.3.54 S cog cog4633
BFDKIJLE_01088 1.8e-63 copY K Copper transport repressor, CopY TcrY family
BFDKIJLE_01089 1.4e-187 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
BFDKIJLE_01090 2.5e-10 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BFDKIJLE_01091 3.3e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BFDKIJLE_01092 2.1e-155 czcD P cation diffusion facilitator family transporter
BFDKIJLE_01093 7.4e-92 K Transcriptional regulator, TetR family
BFDKIJLE_01094 7.6e-69 S Protein of unknown function with HXXEE motif
BFDKIJLE_01095 7e-11
BFDKIJLE_01096 6.5e-81 tnp L DDE domain
BFDKIJLE_01097 1.8e-150 cbiO2 P ABC transporter, ATP-binding protein
BFDKIJLE_01098 7.8e-157 P ATPase activity
BFDKIJLE_01099 1.7e-132 cbiQ P cobalt transport
BFDKIJLE_01100 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
BFDKIJLE_01101 2.9e-137 S Phenazine biosynthesis protein
BFDKIJLE_01102 1.8e-265 proWX P ABC transporter
BFDKIJLE_01103 2.5e-127 proV E abc transporter atp-binding protein
BFDKIJLE_01104 1.1e-145 1.6.5.2 GM NmrA family
BFDKIJLE_01105 2.4e-64 mgrA K Transcriptional regulator, MarR family
BFDKIJLE_01106 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
BFDKIJLE_01107 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
BFDKIJLE_01110 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BFDKIJLE_01112 1.1e-136 IQ Acetoin reductase
BFDKIJLE_01113 6.9e-44 pspE P Rhodanese-like protein
BFDKIJLE_01114 1e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BFDKIJLE_01115 2.7e-221 XK27_05470 E Methionine synthase
BFDKIJLE_01116 3.6e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BFDKIJLE_01117 1.2e-239 T PhoQ Sensor
BFDKIJLE_01118 2.2e-122 KT Transcriptional regulatory protein, C terminal
BFDKIJLE_01119 3.4e-149 S TraX protein
BFDKIJLE_01120 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFDKIJLE_01121 3.3e-155 dprA LU DNA protecting protein DprA
BFDKIJLE_01122 8e-163 GK ROK family
BFDKIJLE_01123 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFDKIJLE_01124 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFDKIJLE_01125 4e-127 K DNA-binding helix-turn-helix protein
BFDKIJLE_01126 1.7e-90 niaR S small molecule binding protein (contains 3H domain)
BFDKIJLE_01127 2.7e-86
BFDKIJLE_01128 1.7e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFDKIJLE_01129 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BFDKIJLE_01130 7.7e-126 gntR1 K transcriptional
BFDKIJLE_01131 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BFDKIJLE_01132 3.6e-100 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BFDKIJLE_01133 1e-187 adhP 1.1.1.1 C alcohol dehydrogenase
BFDKIJLE_01134 1e-44
BFDKIJLE_01135 2.6e-51
BFDKIJLE_01136 5.7e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFDKIJLE_01137 8.7e-156 aatB ET ABC transporter substrate-binding protein
BFDKIJLE_01138 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_01139 1.8e-105 artQ P ABC transporter (Permease
BFDKIJLE_01140 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
BFDKIJLE_01141 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BFDKIJLE_01142 8.4e-165 cpsY K Transcriptional regulator
BFDKIJLE_01143 2.7e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
BFDKIJLE_01144 3.1e-168 yeiH S Membrane
BFDKIJLE_01146 3.4e-09
BFDKIJLE_01147 7.6e-291 adcA P Belongs to the bacterial solute-binding protein 9 family
BFDKIJLE_01148 1.9e-147 XK27_10720 D peptidase activity
BFDKIJLE_01149 8.1e-276 pepD E Dipeptidase
BFDKIJLE_01150 5.7e-161 whiA K May be required for sporulation
BFDKIJLE_01151 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BFDKIJLE_01152 6.5e-162 rapZ S Displays ATPase and GTPase activities
BFDKIJLE_01153 3.5e-135 yejC S cyclic nucleotide-binding protein
BFDKIJLE_01154 1.5e-201 D nuclear chromosome segregation
BFDKIJLE_01155 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
BFDKIJLE_01156 1.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BFDKIJLE_01157 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
BFDKIJLE_01158 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFDKIJLE_01159 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
BFDKIJLE_01160 3.7e-19
BFDKIJLE_01161 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BFDKIJLE_01162 1.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BFDKIJLE_01163 7.1e-78 ypmB S Protein conserved in bacteria
BFDKIJLE_01164 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BFDKIJLE_01165 4.3e-115 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
BFDKIJLE_01166 2.7e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
BFDKIJLE_01167 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
BFDKIJLE_01168 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
BFDKIJLE_01169 3.2e-187 tcsA S membrane
BFDKIJLE_01170 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BFDKIJLE_01171 1.6e-109 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFDKIJLE_01172 1.4e-229 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BFDKIJLE_01173 1.1e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
BFDKIJLE_01174 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
BFDKIJLE_01175 1e-29 rpsT J Binds directly to 16S ribosomal RNA
BFDKIJLE_01176 9.8e-237 T PhoQ Sensor
BFDKIJLE_01177 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BFDKIJLE_01178 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BFDKIJLE_01179 4.2e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
BFDKIJLE_01180 3.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFDKIJLE_01181 2.7e-92 panT S ECF transporter, substrate-specific component
BFDKIJLE_01182 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
BFDKIJLE_01183 1.6e-165 metF 1.5.1.20 E reductase
BFDKIJLE_01184 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFDKIJLE_01186 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
BFDKIJLE_01187 0.0 3.6.3.8 P cation transport ATPase
BFDKIJLE_01188 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BFDKIJLE_01189 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BFDKIJLE_01190 4.7e-235 dltB M Membrane protein involved in D-alanine export
BFDKIJLE_01191 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BFDKIJLE_01192 0.0 XK27_10035 V abc transporter atp-binding protein
BFDKIJLE_01193 1.2e-289 yfiB1 V abc transporter atp-binding protein
BFDKIJLE_01194 3.2e-99 pvaA M lytic transglycosylase activity
BFDKIJLE_01195 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
BFDKIJLE_01196 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFDKIJLE_01197 1.1e-56 XK27_05710 K Acetyltransferase (GNAT) domain
BFDKIJLE_01198 2.6e-101 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BFDKIJLE_01199 6.4e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BFDKIJLE_01200 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFDKIJLE_01201 7.3e-109 tdk 2.7.1.21 F thymidine kinase
BFDKIJLE_01202 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFDKIJLE_01203 6e-151 gst O Glutathione S-transferase
BFDKIJLE_01204 2.2e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
BFDKIJLE_01205 2.9e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BFDKIJLE_01206 4.4e-45 rpmE2 J 50S ribosomal protein L31
BFDKIJLE_01207 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
BFDKIJLE_01208 7.6e-164 ypuA S secreted protein
BFDKIJLE_01209 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
BFDKIJLE_01210 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
BFDKIJLE_01211 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFDKIJLE_01212 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BFDKIJLE_01213 1.4e-256 noxE P NADH oxidase
BFDKIJLE_01214 1.1e-294 yfmM S abc transporter atp-binding protein
BFDKIJLE_01215 8.9e-82 XK27_01265 S ECF-type riboflavin transporter, S component
BFDKIJLE_01216 6.1e-149 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BFDKIJLE_01217 3.3e-86 S ECF-type riboflavin transporter, S component
BFDKIJLE_01219 1.3e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BFDKIJLE_01220 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
BFDKIJLE_01222 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BFDKIJLE_01223 6.6e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BFDKIJLE_01224 4.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFDKIJLE_01225 2.9e-22 WQ51_00220 K Helix-turn-helix domain
BFDKIJLE_01226 7e-90 S Protein of unknown function (DUF3278)
BFDKIJLE_01227 0.0 smc D Required for chromosome condensation and partitioning
BFDKIJLE_01228 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BFDKIJLE_01229 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFDKIJLE_01230 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFDKIJLE_01232 4.5e-120 alkD L DNA alkylation repair enzyme
BFDKIJLE_01233 5e-290 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFDKIJLE_01234 2.3e-87 pat 2.3.1.183 M acetyltransferase
BFDKIJLE_01235 2e-258 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFDKIJLE_01236 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
BFDKIJLE_01237 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFDKIJLE_01238 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BFDKIJLE_01239 1.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
BFDKIJLE_01240 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
BFDKIJLE_01241 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
BFDKIJLE_01242 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
BFDKIJLE_01243 1.9e-133 L Integrase
BFDKIJLE_01244 2e-202 S Protein of unknown function DUF262
BFDKIJLE_01245 2.1e-151 S Protein of unknown function DUF262
BFDKIJLE_01246 1.4e-37 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
BFDKIJLE_01248 3.1e-79 3.4.21.89 S RDD family
BFDKIJLE_01249 2.4e-151 K sequence-specific DNA binding
BFDKIJLE_01250 3.9e-148 V ABC transporter, ATP-binding protein
BFDKIJLE_01251 1.9e-95 S ABC-2 family transporter protein
BFDKIJLE_01252 5.1e-130 K sequence-specific DNA binding
BFDKIJLE_01253 6.9e-47
BFDKIJLE_01254 3.1e-75 K Acetyltransferase (GNAT) domain
BFDKIJLE_01255 1.9e-141 S ABC-2 family transporter protein
BFDKIJLE_01256 5.8e-141 S ABC-2 family transporter protein
BFDKIJLE_01257 7.2e-186 S abc transporter atp-binding protein
BFDKIJLE_01260 1.1e-130 S Protein of unknown function DUF262
BFDKIJLE_01261 4.7e-208 S Protein of unknown function DUF262
BFDKIJLE_01262 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BFDKIJLE_01263 5.9e-189 desK 2.7.13.3 T Histidine kinase
BFDKIJLE_01264 9e-133 yvfS V ABC-2 type transporter
BFDKIJLE_01265 1e-159 XK27_09825 V abc transporter atp-binding protein
BFDKIJLE_01268 6.6e-165 yocS S Transporter
BFDKIJLE_01269 2.3e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
BFDKIJLE_01270 9.9e-132 yvfS V Transporter
BFDKIJLE_01271 2.2e-157 XK27_09825 V abc transporter atp-binding protein
BFDKIJLE_01272 4.1e-15 liaI KT membrane
BFDKIJLE_01273 4.4e-30 liaI KT membrane
BFDKIJLE_01274 6.1e-93 XK27_05000 S metal cluster binding
BFDKIJLE_01275 0.0 V ABC transporter (permease)
BFDKIJLE_01276 1.1e-133 macB2 V ABC transporter, ATP-binding protein
BFDKIJLE_01277 1.1e-149 T Histidine kinase
BFDKIJLE_01278 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BFDKIJLE_01279 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BFDKIJLE_01280 4.2e-223 pbuX F xanthine permease
BFDKIJLE_01281 1.2e-57 pdxH S pyridoxamine 5'-phosphate oxidase
BFDKIJLE_01282 2.1e-280 V (ABC) transporter
BFDKIJLE_01283 5.4e-142 K sequence-specific DNA binding
BFDKIJLE_01284 4.3e-242 norM V Multidrug efflux pump
BFDKIJLE_01286 2.8e-27 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFDKIJLE_01287 1.8e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFDKIJLE_01288 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
BFDKIJLE_01289 2.3e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
BFDKIJLE_01290 1.8e-59 S Protein of unknown function (DUF3290)
BFDKIJLE_01291 6.2e-106 S Protein of unknown function (DUF421)
BFDKIJLE_01292 2.5e-13 csbD K CsbD-like
BFDKIJLE_01293 4e-87 S Carbohydrate-binding domain-containing protein Cthe_2159
BFDKIJLE_01294 5.7e-37 XK27_01300 S ASCH
BFDKIJLE_01295 1.8e-211 yfnA E amino acid
BFDKIJLE_01296 0.0 S dextransucrase activity
BFDKIJLE_01297 1.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
BFDKIJLE_01298 1.5e-42 S Sugar efflux transporter for intercellular exchange
BFDKIJLE_01299 1.4e-201 P FtsX-like permease family
BFDKIJLE_01300 1.6e-123 V abc transporter atp-binding protein
BFDKIJLE_01301 1.9e-98 K WHG domain
BFDKIJLE_01302 3.2e-172 ydhF S Aldo keto reductase
BFDKIJLE_01303 1.1e-06 S Protein of unknown function (DUF3169)
BFDKIJLE_01304 2.5e-27 XK27_07105 K transcriptional
BFDKIJLE_01305 1.5e-28
BFDKIJLE_01306 4.1e-107 XK27_02070 S nitroreductase
BFDKIJLE_01307 4.3e-144 1.13.11.2 S glyoxalase
BFDKIJLE_01308 1.1e-77 ywnA K Transcriptional regulator
BFDKIJLE_01309 2.2e-154 E Alpha/beta hydrolase of unknown function (DUF915)
BFDKIJLE_01310 3.6e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BFDKIJLE_01311 1.7e-168 bcrA V abc transporter atp-binding protein
BFDKIJLE_01312 1.2e-127 S ABC-2 family transporter protein
BFDKIJLE_01313 4.8e-57 2.1.1.72 S Adenine-specific methyltransferase EcoRI
BFDKIJLE_01314 2.4e-92 S Psort location Cytoplasmic, score
BFDKIJLE_01315 2.9e-146 T PhoQ Sensor
BFDKIJLE_01316 9.9e-126 T Xre family transcriptional regulator
BFDKIJLE_01317 1.4e-110 drgA C nitroreductase
BFDKIJLE_01318 4.2e-100 yoaK S Protein of unknown function (DUF1275)
BFDKIJLE_01319 4e-40 DJ nuclease activity
BFDKIJLE_01320 1.1e-30 XK27_10490
BFDKIJLE_01321 1.2e-157 yvgN C reductase
BFDKIJLE_01322 1.4e-209 S Tetratricopeptide repeat
BFDKIJLE_01323 0.0 lacL 3.2.1.23 G -beta-galactosidase
BFDKIJLE_01324 0.0 lacS G transporter
BFDKIJLE_01325 8.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BFDKIJLE_01326 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BFDKIJLE_01327 3.2e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BFDKIJLE_01328 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFDKIJLE_01329 7e-181 galR K Transcriptional regulator
BFDKIJLE_01330 7.1e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
BFDKIJLE_01331 1.6e-123 L Helix-turn-helix domain
BFDKIJLE_01332 3.2e-145 L Integrase core domain protein
BFDKIJLE_01333 1.7e-222 vncS 2.7.13.3 T Histidine kinase
BFDKIJLE_01334 2.2e-114 K Response regulator receiver domain protein
BFDKIJLE_01335 1.1e-235 vex3 V Efflux ABC transporter, permease protein
BFDKIJLE_01336 6.6e-108 vex2 V abc transporter atp-binding protein
BFDKIJLE_01337 7.5e-180 vex1 V Efflux ABC transporter, permease protein
BFDKIJLE_01338 3.3e-283 XK27_07020 S Belongs to the UPF0371 family
BFDKIJLE_01340 2.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
BFDKIJLE_01341 1.1e-178 XK27_10475 S oxidoreductase
BFDKIJLE_01342 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
BFDKIJLE_01343 1.2e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
BFDKIJLE_01344 1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
BFDKIJLE_01345 4.5e-225 thrE K Psort location CytoplasmicMembrane, score
BFDKIJLE_01346 3.2e-134 T Ser Thr phosphatase family protein
BFDKIJLE_01347 5.5e-34 S Immunity protein 41
BFDKIJLE_01348 1.4e-14 S integral membrane protein
BFDKIJLE_01349 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
BFDKIJLE_01350 1.7e-107 yhfC S Putative membrane peptidase family (DUF2324)
BFDKIJLE_01352 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_01355 2.7e-248 S dextransucrase activity
BFDKIJLE_01356 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_01357 0.0 S dextransucrase activity
BFDKIJLE_01358 6.6e-254 S dextransucrase activity
BFDKIJLE_01359 0.0 S dextransucrase activity
BFDKIJLE_01360 8.2e-85 S dextransucrase activity
BFDKIJLE_01361 5.7e-170 S dextransucrase activity
BFDKIJLE_01362 4.7e-207 S dextransucrase activity
BFDKIJLE_01363 1.2e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BFDKIJLE_01364 2.6e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BFDKIJLE_01365 8.9e-297 S dextransucrase activity
BFDKIJLE_01366 1.8e-135 S dextransucrase activity
BFDKIJLE_01367 0.0 M Putative cell wall binding repeat
BFDKIJLE_01369 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BFDKIJLE_01370 1.2e-161 mleP S auxin efflux carrier
BFDKIJLE_01371 2.2e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
BFDKIJLE_01372 2.1e-47 K Helix-turn-helix
BFDKIJLE_01373 1.8e-119 mleR K malolactic fermentation system
BFDKIJLE_01374 2.7e-113 M Putative cell wall binding repeat
BFDKIJLE_01375 1.6e-132 XK27_00785 S CAAX protease self-immunity
BFDKIJLE_01376 2.4e-235 EGP Major facilitator Superfamily
BFDKIJLE_01377 1.9e-63 rmaI K Transcriptional regulator, MarR family
BFDKIJLE_01378 6.3e-94 maa 2.3.1.79 GK Maltose O-acetyltransferase
BFDKIJLE_01379 1.5e-135 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
BFDKIJLE_01380 0.0 3.5.1.28 M domain protein
BFDKIJLE_01381 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BFDKIJLE_01382 8.6e-22
BFDKIJLE_01387 4.8e-309 sraP UW Hep Hag repeat protein
BFDKIJLE_01388 1.2e-185 nss M transferase activity, transferring glycosyl groups
BFDKIJLE_01389 3.6e-16 S Accessory secretory protein Sec, Asp5
BFDKIJLE_01390 2.6e-17 S Accessory secretory protein Sec Asp4
BFDKIJLE_01391 2e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BFDKIJLE_01392 1.8e-281 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BFDKIJLE_01393 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BFDKIJLE_01394 1.6e-76 asp3 S Accessory Sec system protein Asp3
BFDKIJLE_01395 4.1e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
BFDKIJLE_01396 2.3e-287 asp1 S Accessory Sec system protein Asp1
BFDKIJLE_01397 1.2e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
BFDKIJLE_01398 0.0 M family 8
BFDKIJLE_01399 0.0 sbcC L ATPase involved in DNA repair
BFDKIJLE_01400 5.1e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BFDKIJLE_01401 0.0 GM domain, Protein
BFDKIJLE_01402 0.0 zmpB M signal peptide protein, YSIRK family
BFDKIJLE_01403 0.0 M domain protein
BFDKIJLE_01404 2e-40 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFDKIJLE_01406 1.1e-09
BFDKIJLE_01407 3.1e-188 XK27_10075 S abc transporter atp-binding protein
BFDKIJLE_01408 0.0 V abc transporter atp-binding protein
BFDKIJLE_01409 8e-297 V abc transporter atp-binding protein
BFDKIJLE_01410 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
BFDKIJLE_01412 7.5e-283 S Protein of unknown function (DUF3114)
BFDKIJLE_01413 7.6e-100 2.3.1.128 K Acetyltransferase GNAT Family
BFDKIJLE_01414 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BFDKIJLE_01415 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
BFDKIJLE_01416 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
BFDKIJLE_01417 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFDKIJLE_01418 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFDKIJLE_01419 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BFDKIJLE_01420 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BFDKIJLE_01421 1.1e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
BFDKIJLE_01422 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BFDKIJLE_01423 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFDKIJLE_01426 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BFDKIJLE_01427 1.9e-170 vraS 2.7.13.3 T Histidine kinase
BFDKIJLE_01428 3.6e-115 yvqF S Membrane
BFDKIJLE_01429 5.9e-103 kcsA P Ion transport protein
BFDKIJLE_01430 1.7e-292 prkC 2.7.11.1 KLT serine threonine protein kinase
BFDKIJLE_01431 1.5e-135 stp 3.1.3.16 T phosphatase
BFDKIJLE_01432 2.7e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFDKIJLE_01433 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFDKIJLE_01434 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFDKIJLE_01435 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
BFDKIJLE_01436 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BFDKIJLE_01437 1.8e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BFDKIJLE_01438 1.2e-146 XK27_02985 S overlaps another CDS with the same product name
BFDKIJLE_01439 1.3e-145 supH S overlaps another CDS with the same product name
BFDKIJLE_01440 6.1e-61 yvoA_1 K Transcriptional
BFDKIJLE_01441 1.8e-119 skfE V abc transporter atp-binding protein
BFDKIJLE_01442 3.8e-129 V Psort location CytoplasmicMembrane, score
BFDKIJLE_01443 4.7e-171 oppF P Belongs to the ABC transporter superfamily
BFDKIJLE_01444 5.1e-201 oppD P Belongs to the ABC transporter superfamily
BFDKIJLE_01445 3.8e-165 amiD P ABC transporter (Permease
BFDKIJLE_01446 2.5e-275 amiC P ABC transporter (Permease
BFDKIJLE_01447 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
BFDKIJLE_01448 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BFDKIJLE_01449 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BFDKIJLE_01450 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BFDKIJLE_01451 2.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFDKIJLE_01452 6.7e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
BFDKIJLE_01453 2.4e-101 yjbK S Adenylate cyclase
BFDKIJLE_01454 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFDKIJLE_01455 5.2e-209 iscS 2.8.1.7 E Cysteine desulfurase
BFDKIJLE_01456 8.2e-60 XK27_04120 S Putative amino acid metabolism
BFDKIJLE_01457 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BFDKIJLE_01458 5.5e-132 puuD T peptidase C26
BFDKIJLE_01459 4.5e-118 radC E Belongs to the UPF0758 family
BFDKIJLE_01460 1e-167
BFDKIJLE_01461 6.9e-43 M Psort location CytoplasmicMembrane, score
BFDKIJLE_01462 1.6e-155 rfbJ M Glycosyl transferase family 2
BFDKIJLE_01463 0.0 rgpF M Rhamnan synthesis protein F
BFDKIJLE_01464 9.6e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BFDKIJLE_01465 3.1e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BFDKIJLE_01466 5.2e-142 rgpC GM Transport permease protein
BFDKIJLE_01467 7.5e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
BFDKIJLE_01468 1.1e-214 rgpA GT4 M Domain of unknown function (DUF1972)
BFDKIJLE_01469 6.5e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BFDKIJLE_01470 2.7e-212 S Predicted membrane protein (DUF2142)
BFDKIJLE_01471 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
BFDKIJLE_01472 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
BFDKIJLE_01473 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BFDKIJLE_01474 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BFDKIJLE_01475 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BFDKIJLE_01476 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BFDKIJLE_01477 6.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
BFDKIJLE_01478 1.5e-208 arcT 2.6.1.1 E Aminotransferase
BFDKIJLE_01479 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
BFDKIJLE_01480 1.9e-139 ET ABC transporter
BFDKIJLE_01481 9.2e-83 mutT 3.6.1.55 F Nudix family
BFDKIJLE_01482 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BFDKIJLE_01484 2.1e-163 S CAAX amino terminal protease family protein
BFDKIJLE_01485 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
BFDKIJLE_01486 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_01487 2.2e-17 XK27_00735
BFDKIJLE_01488 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFDKIJLE_01490 8.4e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BFDKIJLE_01492 2.7e-10 O ADP-ribosylglycohydrolase
BFDKIJLE_01493 1.5e-62 paaI Q protein possibly involved in aromatic compounds catabolism
BFDKIJLE_01494 9.2e-62 ycaO O OsmC-like protein
BFDKIJLE_01496 7e-148 EG Permeases of the drug metabolite transporter (DMT) superfamily
BFDKIJLE_01498 2.6e-112 serB 3.1.3.3 E phosphoserine phosphatase
BFDKIJLE_01499 8.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BFDKIJLE_01500 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BFDKIJLE_01501 1e-96 3.1.3.18 S IA, variant 1
BFDKIJLE_01502 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
BFDKIJLE_01503 7.7e-56 lrgA S Effector of murein hydrolase LrgA
BFDKIJLE_01505 5.4e-68 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
BFDKIJLE_01506 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFDKIJLE_01507 3e-104 wecD M Acetyltransferase (GNAT) domain
BFDKIJLE_01508 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFDKIJLE_01509 4.4e-158 GK ROK family
BFDKIJLE_01510 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
BFDKIJLE_01511 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
BFDKIJLE_01512 1.8e-203 potD P spermidine putrescine ABC transporter
BFDKIJLE_01513 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
BFDKIJLE_01514 1.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
BFDKIJLE_01515 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BFDKIJLE_01516 1.8e-167 murB 1.3.1.98 M cell wall formation
BFDKIJLE_01517 1.1e-78 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BFDKIJLE_01518 1.6e-58 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFDKIJLE_01519 1.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
BFDKIJLE_01520 1e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFDKIJLE_01521 3.8e-99 folE 3.5.4.16 F gtp cyclohydrolase
BFDKIJLE_01522 0.0 ydaO E amino acid
BFDKIJLE_01523 4.3e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BFDKIJLE_01524 1.5e-36 ylqC L Belongs to the UPF0109 family
BFDKIJLE_01525 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BFDKIJLE_01527 1.1e-210 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01528 4.2e-122 agrA KT phosphorelay signal transduction system
BFDKIJLE_01529 7.4e-162 O protein import
BFDKIJLE_01530 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
BFDKIJLE_01531 3.7e-17 yjdB S Domain of unknown function (DUF4767)
BFDKIJLE_01532 1.4e-62 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFDKIJLE_01534 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
BFDKIJLE_01535 4.9e-71 S QueT transporter
BFDKIJLE_01537 1.2e-169 yfjR K regulation of single-species biofilm formation
BFDKIJLE_01539 1.8e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BFDKIJLE_01540 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFDKIJLE_01541 3.7e-85 ccl S cog cog4708
BFDKIJLE_01542 8.4e-160 rbn E Belongs to the UPF0761 family
BFDKIJLE_01543 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
BFDKIJLE_01544 1.9e-231 ytoI K transcriptional regulator containing CBS domains
BFDKIJLE_01545 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
BFDKIJLE_01546 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFDKIJLE_01547 0.0 comEC S Competence protein ComEC
BFDKIJLE_01548 3.6e-91 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
BFDKIJLE_01549 7e-141 plsC 2.3.1.51 I Acyltransferase
BFDKIJLE_01550 6.7e-157 nodB3 G deacetylase
BFDKIJLE_01551 3.4e-127 yabB 2.1.1.223 L Methyltransferase
BFDKIJLE_01552 2.3e-41 yazA L endonuclease containing a URI domain
BFDKIJLE_01553 4.5e-46
BFDKIJLE_01554 1.6e-55 S there are four paralogs in L.lactis
BFDKIJLE_01555 1.7e-253 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BFDKIJLE_01556 4.8e-152 corA P CorA-like protein
BFDKIJLE_01557 3.3e-62 yjqA S Bacterial PH domain
BFDKIJLE_01558 1.7e-99 thiT S Thiamine transporter
BFDKIJLE_01559 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BFDKIJLE_01560 1.4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
BFDKIJLE_01561 2e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BFDKIJLE_01565 1.6e-123 L Helix-turn-helix domain
BFDKIJLE_01566 3.2e-145 L Integrase core domain protein
BFDKIJLE_01567 7.4e-155 cjaA ET ABC transporter substrate-binding protein
BFDKIJLE_01568 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_01569 3e-106 P ABC transporter (Permease
BFDKIJLE_01570 1.3e-114 papP P ABC transporter (Permease
BFDKIJLE_01571 2.3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BFDKIJLE_01572 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
BFDKIJLE_01573 0.0 copA 3.6.3.54 P P-type ATPase
BFDKIJLE_01574 1.5e-71 copY K negative regulation of transcription, DNA-templated
BFDKIJLE_01575 7.2e-177 EGP Major facilitator Superfamily
BFDKIJLE_01577 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BFDKIJLE_01578 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BFDKIJLE_01579 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
BFDKIJLE_01580 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
BFDKIJLE_01581 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFDKIJLE_01582 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
BFDKIJLE_01583 1.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BFDKIJLE_01584 9.8e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
BFDKIJLE_01585 7e-59
BFDKIJLE_01586 0.0 ctpE P E1-E2 ATPase
BFDKIJLE_01587 5.7e-23 3.2.1.26 GH32 G Glycosyl hydrolase family 32
BFDKIJLE_01588 4.5e-93
BFDKIJLE_01589 1.5e-70
BFDKIJLE_01590 3.5e-43
BFDKIJLE_01591 6.2e-48
BFDKIJLE_01592 8.8e-47
BFDKIJLE_01593 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFDKIJLE_01595 1.9e-124 V abc transporter atp-binding protein
BFDKIJLE_01596 0.0 V ABC transporter (Permease
BFDKIJLE_01597 4.9e-91 K transcriptional regulator, MerR family
BFDKIJLE_01598 3.2e-18 K transcriptional regulator, MerR family
BFDKIJLE_01599 3.2e-104 dnaQ 2.7.7.7 L DNA polymerase III
BFDKIJLE_01600 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
BFDKIJLE_01601 1.2e-64 XK27_02560 S cog cog2151
BFDKIJLE_01602 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BFDKIJLE_01603 4e-223 ytfP S Flavoprotein
BFDKIJLE_01605 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BFDKIJLE_01606 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
BFDKIJLE_01607 7.1e-176 ecsB U Bacterial ABC transporter protein EcsB
BFDKIJLE_01608 2.2e-131 ecsA V abc transporter atp-binding protein
BFDKIJLE_01609 1.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BFDKIJLE_01613 1.6e-103
BFDKIJLE_01615 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
BFDKIJLE_01617 7.2e-195 ylbM S Belongs to the UPF0348 family
BFDKIJLE_01618 8.4e-139 yqeM Q Methyltransferase domain protein
BFDKIJLE_01619 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BFDKIJLE_01620 3.5e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
BFDKIJLE_01621 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFDKIJLE_01622 7.7e-49 yhbY J RNA-binding protein
BFDKIJLE_01623 1.5e-211 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
BFDKIJLE_01624 5.1e-98 yqeG S hydrolase of the HAD superfamily
BFDKIJLE_01625 9.1e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BFDKIJLE_01626 3.9e-190 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
BFDKIJLE_01627 1.8e-60
BFDKIJLE_01628 7e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BFDKIJLE_01629 5e-58
BFDKIJLE_01630 5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
BFDKIJLE_01631 1.8e-273 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
BFDKIJLE_01632 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
BFDKIJLE_01633 7.2e-31 S PQ loop repeat
BFDKIJLE_01634 8.3e-284 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BFDKIJLE_01636 1.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFDKIJLE_01637 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BFDKIJLE_01638 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BFDKIJLE_01639 1.1e-230 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BFDKIJLE_01640 9.1e-189 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BFDKIJLE_01641 1.3e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
BFDKIJLE_01642 1.1e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
BFDKIJLE_01643 1.3e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BFDKIJLE_01644 2.9e-99 pncA Q isochorismatase
BFDKIJLE_01645 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BFDKIJLE_01646 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
BFDKIJLE_01647 1.2e-74 XK27_03180 T universal stress protein
BFDKIJLE_01649 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFDKIJLE_01650 8.2e-09 MU outer membrane autotransporter barrel domain protein
BFDKIJLE_01651 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
BFDKIJLE_01652 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
BFDKIJLE_01653 0.0 yjcE P NhaP-type Na H and K H antiporters
BFDKIJLE_01655 7.2e-95 ytqB J (SAM)-dependent
BFDKIJLE_01656 1e-181 yhcC S radical SAM protein
BFDKIJLE_01657 1.2e-186 ylbL T Belongs to the peptidase S16 family
BFDKIJLE_01658 1.9e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFDKIJLE_01659 2.1e-91 rsmD 2.1.1.171 L Methyltransferase
BFDKIJLE_01660 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BFDKIJLE_01661 5e-10 S Protein of unknown function (DUF4059)
BFDKIJLE_01662 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
BFDKIJLE_01663 3e-162 yxeN P ABC transporter (Permease
BFDKIJLE_01664 3.3e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BFDKIJLE_01665 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BFDKIJLE_01666 3.6e-35
BFDKIJLE_01667 5.6e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFDKIJLE_01668 0.0 pflB 2.3.1.54 C formate acetyltransferase'
BFDKIJLE_01670 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
BFDKIJLE_01671 2.7e-143 cah 4.2.1.1 P carbonic anhydrase
BFDKIJLE_01672 2.9e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BFDKIJLE_01673 5.9e-217 L the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_01674 2e-19 L Transposase
BFDKIJLE_01675 1.9e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
BFDKIJLE_01676 7e-141 cppA E CppA N-terminal
BFDKIJLE_01677 1.4e-92 V CAAX protease self-immunity
BFDKIJLE_01678 4.7e-149 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
BFDKIJLE_01679 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BFDKIJLE_01680 3.7e-45 spiA K sequence-specific DNA binding
BFDKIJLE_01683 1.8e-133 agrA KT LytTr DNA-binding domain
BFDKIJLE_01684 1.9e-218 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
BFDKIJLE_01689 3.3e-25 S Bacteriocin class II with double-glycine leader peptide
BFDKIJLE_01690 0.0 mdlB V abc transporter atp-binding protein
BFDKIJLE_01691 0.0 mdlA V abc transporter atp-binding protein
BFDKIJLE_01693 1.2e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
BFDKIJLE_01694 5.1e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BFDKIJLE_01695 5.7e-63 yutD J protein conserved in bacteria
BFDKIJLE_01696 1.1e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
BFDKIJLE_01698 1.2e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BFDKIJLE_01699 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFDKIJLE_01700 0.0 ftsI 3.4.16.4 M penicillin-binding protein
BFDKIJLE_01701 4e-45 ftsL D cell division protein FtsL
BFDKIJLE_01702 6.7e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BFDKIJLE_01703 2.4e-94
BFDKIJLE_01706 1.5e-44 yhaI J Protein of unknown function (DUF805)
BFDKIJLE_01707 3.4e-62 yhaI J Protein of unknown function (DUF805)
BFDKIJLE_01708 2.3e-32 yhaI J Protein of unknown function (DUF805)
BFDKIJLE_01709 3.2e-60 yhaI J Membrane
BFDKIJLE_01710 3.5e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFDKIJLE_01711 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BFDKIJLE_01712 2.4e-284 XK27_00765
BFDKIJLE_01713 4e-133 ecsA_2 V abc transporter atp-binding protein
BFDKIJLE_01714 4e-125 S Protein of unknown function (DUF554)
BFDKIJLE_01715 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BFDKIJLE_01716 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BFDKIJLE_01717 4.7e-244 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01718 1.1e-234 dcuS 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01719 5.2e-14
BFDKIJLE_01722 5.8e-146 V Psort location CytoplasmicMembrane, score
BFDKIJLE_01724 8.6e-298 O MreB/Mbl protein
BFDKIJLE_01725 1.9e-192 mccF V LD-carboxypeptidase
BFDKIJLE_01726 6.3e-120 liaI S membrane
BFDKIJLE_01727 7.5e-74 XK27_02470 K LytTr DNA-binding domain protein
BFDKIJLE_01728 0.0 KT response to antibiotic
BFDKIJLE_01729 2.1e-102 yebC M Membrane
BFDKIJLE_01730 1.2e-258 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
BFDKIJLE_01731 4e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BFDKIJLE_01733 2.9e-31 yozG K Transcriptional regulator
BFDKIJLE_01737 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFDKIJLE_01738 4.1e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFDKIJLE_01739 8.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BFDKIJLE_01740 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFDKIJLE_01741 2.8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFDKIJLE_01742 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BFDKIJLE_01744 6.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
BFDKIJLE_01745 1.3e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
BFDKIJLE_01746 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BFDKIJLE_01747 1.7e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
BFDKIJLE_01748 3.7e-179 scrR K purine nucleotide biosynthetic process
BFDKIJLE_01749 4e-72 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFDKIJLE_01750 1.7e-61 yqhY S protein conserved in bacteria
BFDKIJLE_01751 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFDKIJLE_01752 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
BFDKIJLE_01753 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
BFDKIJLE_01755 5.1e-145 V 'abc transporter, ATP-binding protein
BFDKIJLE_01756 2.8e-32 blpT
BFDKIJLE_01760 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFDKIJLE_01761 1.9e-167 corA P COG0598 Mg2 and Co2 transporters
BFDKIJLE_01762 5e-122 XK27_01040 S Protein of unknown function (DUF1129)
BFDKIJLE_01764 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFDKIJLE_01765 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BFDKIJLE_01766 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
BFDKIJLE_01767 5.5e-42 XK27_05745
BFDKIJLE_01768 3.9e-215 mutY L A G-specific adenine glycosylase
BFDKIJLE_01771 4e-36
BFDKIJLE_01773 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFDKIJLE_01774 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BFDKIJLE_01775 3e-93 cvpA S toxin biosynthetic process
BFDKIJLE_01776 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BFDKIJLE_01777 1.5e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFDKIJLE_01778 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BFDKIJLE_01779 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BFDKIJLE_01780 1.3e-46 azlD S branched-chain amino acid
BFDKIJLE_01781 1.5e-113 azlC E AzlC protein
BFDKIJLE_01782 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFDKIJLE_01783 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BFDKIJLE_01784 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
BFDKIJLE_01785 4.3e-33 ykzG S Belongs to the UPF0356 family
BFDKIJLE_01786 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BFDKIJLE_01787 3.6e-114 pscB M CHAP domain protein
BFDKIJLE_01788 2.2e-262 glnA 6.3.1.2 E glutamine synthetase
BFDKIJLE_01789 8.5e-63 glnR K Transcriptional regulator
BFDKIJLE_01790 5.6e-86 S Fusaric acid resistance protein-like
BFDKIJLE_01791 9.9e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BFDKIJLE_01792 1.2e-118
BFDKIJLE_01793 1.3e-185 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BFDKIJLE_01794 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFDKIJLE_01795 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BFDKIJLE_01796 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BFDKIJLE_01797 5.3e-142 purR 2.4.2.7 F operon repressor
BFDKIJLE_01798 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
BFDKIJLE_01799 3.2e-170 rmuC S RmuC domain protein
BFDKIJLE_01800 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
BFDKIJLE_01801 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BFDKIJLE_01802 3.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BFDKIJLE_01804 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BFDKIJLE_01805 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BFDKIJLE_01806 1.6e-143 tatD L Hydrolase, tatd
BFDKIJLE_01807 1.2e-73 yccU S CoA-binding protein
BFDKIJLE_01808 2.4e-50 trxA O Belongs to the thioredoxin family
BFDKIJLE_01809 1.7e-142 S Macro domain protein
BFDKIJLE_01810 1.8e-61 L thioesterase
BFDKIJLE_01811 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
BFDKIJLE_01814 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BFDKIJLE_01815 3.4e-14 rpmH J Ribosomal protein L34
BFDKIJLE_01816 2.8e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
BFDKIJLE_01817 1.7e-105 K Transcriptional regulator
BFDKIJLE_01818 1.2e-151 jag S RNA-binding protein
BFDKIJLE_01819 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BFDKIJLE_01820 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BFDKIJLE_01821 7.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
BFDKIJLE_01822 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BFDKIJLE_01823 7.2e-130 fasA KT Response regulator of the LytR AlgR family
BFDKIJLE_01824 5.2e-224 fasC 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01825 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01826 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
BFDKIJLE_01827 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
BFDKIJLE_01828 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFDKIJLE_01829 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BFDKIJLE_01830 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BFDKIJLE_01831 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFDKIJLE_01832 1.2e-50 S Protein of unknown function (DUF3397)
BFDKIJLE_01833 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
BFDKIJLE_01834 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
BFDKIJLE_01835 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BFDKIJLE_01836 3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
BFDKIJLE_01837 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BFDKIJLE_01838 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
BFDKIJLE_01839 2.1e-230 XK27_09615 C reductase
BFDKIJLE_01840 2.4e-139 fnt P Formate nitrite transporter
BFDKIJLE_01841 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
BFDKIJLE_01842 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BFDKIJLE_01843 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BFDKIJLE_01844 5.7e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
BFDKIJLE_01845 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFDKIJLE_01846 4.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BFDKIJLE_01847 1.2e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BFDKIJLE_01848 2.4e-141 S HAD hydrolase, family IA, variant
BFDKIJLE_01849 9.8e-160 rrmA 2.1.1.187 Q methyltransferase
BFDKIJLE_01853 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BFDKIJLE_01854 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BFDKIJLE_01855 8.3e-37 yeeD O sulfur carrier activity
BFDKIJLE_01856 6.8e-159 yeeE S Sulphur transport
BFDKIJLE_01857 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BFDKIJLE_01859 4.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BFDKIJLE_01860 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
BFDKIJLE_01861 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
BFDKIJLE_01862 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFDKIJLE_01863 4.8e-101 S CAAX amino terminal protease family protein
BFDKIJLE_01865 3.3e-110 V CAAX protease self-immunity
BFDKIJLE_01866 8.8e-27 lanR K sequence-specific DNA binding
BFDKIJLE_01867 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFDKIJLE_01868 1.7e-176 ytxK 2.1.1.72 L DNA methylase
BFDKIJLE_01869 5.8e-12 comGF U Putative Competence protein ComGF
BFDKIJLE_01870 4.5e-71 comGF U Competence protein ComGF
BFDKIJLE_01871 3.1e-15 NU Type II secretory pathway pseudopilin
BFDKIJLE_01872 8.4e-70 cglD NU Competence protein
BFDKIJLE_01873 2.2e-43 comGC U Required for transformation and DNA binding
BFDKIJLE_01874 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFDKIJLE_01875 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFDKIJLE_01876 1e-68 S cog cog4699
BFDKIJLE_01877 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFDKIJLE_01878 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFDKIJLE_01879 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BFDKIJLE_01880 7.9e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFDKIJLE_01881 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFDKIJLE_01882 2.9e-76 ilvN 2.2.1.6 E Acetolactate synthase
BFDKIJLE_01883 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
BFDKIJLE_01884 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BFDKIJLE_01885 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
BFDKIJLE_01886 1.4e-57 asp S cog cog1302
BFDKIJLE_01887 1.2e-225 norN V Mate efflux family protein
BFDKIJLE_01888 2.7e-277 thrC 4.2.3.1 E Threonine synthase
BFDKIJLE_01891 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BFDKIJLE_01892 0.0 pepO 3.4.24.71 O Peptidase family M13
BFDKIJLE_01893 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BFDKIJLE_01894 9.5e-291 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BFDKIJLE_01895 3.9e-125 treR K trehalose operon
BFDKIJLE_01896 1.9e-95 ywlG S Belongs to the UPF0340 family
BFDKIJLE_01899 3.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
BFDKIJLE_01901 1.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
BFDKIJLE_01902 4.4e-62 rplQ J ribosomal protein l17
BFDKIJLE_01903 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFDKIJLE_01904 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFDKIJLE_01905 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFDKIJLE_01906 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BFDKIJLE_01907 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFDKIJLE_01908 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BFDKIJLE_01909 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BFDKIJLE_01910 5.7e-58 rplO J binds to the 23S rRNA
BFDKIJLE_01911 1.9e-23 rpmD J ribosomal protein l30
BFDKIJLE_01912 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFDKIJLE_01913 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFDKIJLE_01914 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFDKIJLE_01915 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFDKIJLE_01916 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFDKIJLE_01917 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFDKIJLE_01918 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFDKIJLE_01919 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFDKIJLE_01920 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFDKIJLE_01921 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
BFDKIJLE_01922 2.5e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFDKIJLE_01923 2.8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFDKIJLE_01924 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFDKIJLE_01925 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFDKIJLE_01926 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFDKIJLE_01927 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BFDKIJLE_01928 1.3e-103 rplD J Forms part of the polypeptide exit tunnel
BFDKIJLE_01929 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFDKIJLE_01930 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
BFDKIJLE_01931 9.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BFDKIJLE_01932 0.0 XK27_09800 I Acyltransferase
BFDKIJLE_01933 9.7e-36 XK27_09805 S MORN repeat protein
BFDKIJLE_01934 5.8e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BFDKIJLE_01935 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFDKIJLE_01936 1.5e-91 adk 2.7.4.3 F topology modulation protein
BFDKIJLE_01938 4.7e-197 ltrA S Low temperature requirement protein
BFDKIJLE_01939 2.5e-173 yeiH S membrane
BFDKIJLE_01940 8e-88 K sequence-specific DNA binding
BFDKIJLE_01941 1.5e-156 L Replication initiation factor
BFDKIJLE_01942 1.4e-18 S Domain of unknown function (DUF3173)
BFDKIJLE_01943 1.6e-213 int L Belongs to the 'phage' integrase family
BFDKIJLE_01945 4.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
BFDKIJLE_01946 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BFDKIJLE_01947 6.3e-44 yrzL S Belongs to the UPF0297 family
BFDKIJLE_01948 5.2e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFDKIJLE_01949 3.2e-44 yrzB S Belongs to the UPF0473 family
BFDKIJLE_01950 3.6e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
BFDKIJLE_01951 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BFDKIJLE_01952 7.5e-14
BFDKIJLE_01953 3.2e-89 XK27_10930 K acetyltransferase
BFDKIJLE_01954 4.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFDKIJLE_01955 3.6e-123 yaaA S Belongs to the UPF0246 family
BFDKIJLE_01956 9.3e-167 XK27_01785 S cog cog1284
BFDKIJLE_01957 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BFDKIJLE_01959 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
BFDKIJLE_01960 8.3e-233 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BFDKIJLE_01961 1.5e-219 metE 2.1.1.14 E Methionine synthase
BFDKIJLE_01962 5.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BFDKIJLE_01963 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BFDKIJLE_01966 5.9e-152 O AAA domain (Cdc48 subfamily)
BFDKIJLE_01967 7.9e-116
BFDKIJLE_01971 1.1e-44
BFDKIJLE_01972 2.5e-184 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
BFDKIJLE_01973 4.1e-54
BFDKIJLE_01974 3.6e-92 S Plasmid replication protein
BFDKIJLE_01975 4e-19 S MerR HTH family regulatory protein
BFDKIJLE_01976 1.7e-208 sip L Phage integrase, N-terminal SAM-like domain
BFDKIJLE_01977 2.4e-217 KLT Protein tyrosine kinase
BFDKIJLE_01978 3.4e-94 tnp* L An automated process has identified a potential problem with this gene model
BFDKIJLE_01979 4.9e-131 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
BFDKIJLE_01980 1e-57 fruR K transcriptional
BFDKIJLE_01981 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BFDKIJLE_01982 5.4e-162 T Diguanylate cyclase
BFDKIJLE_01984 1.1e-147 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
BFDKIJLE_01985 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
BFDKIJLE_01986 0.0
BFDKIJLE_01991 7e-115 nudL L hydrolase
BFDKIJLE_01992 6.3e-54 K transcriptional regulator, PadR family
BFDKIJLE_01993 8e-68 XK27_06920 S Protein of unknown function (DUF1700)
BFDKIJLE_01994 4.4e-107 S Putative adhesin
BFDKIJLE_01995 2.8e-159 XK27_06930 V domain protein
BFDKIJLE_01996 2.4e-95 XK27_06935 K transcriptional regulator
BFDKIJLE_01997 2e-53 ypaA M Membrane
BFDKIJLE_01998 1.9e-10
BFDKIJLE_01999 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFDKIJLE_02000 1.8e-47 veg S Biofilm formation stimulator VEG
BFDKIJLE_02001 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BFDKIJLE_02002 2.2e-73 rplI J binds to the 23S rRNA
BFDKIJLE_02003 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BFDKIJLE_02004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BFDKIJLE_02005 2.1e-98 yvbG U UPF0056 membrane protein
BFDKIJLE_02006 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BFDKIJLE_02007 2.4e-311 S Bacterial membrane protein, YfhO
BFDKIJLE_02008 1.2e-65 isaA GH23 M Immunodominant staphylococcal antigen A
BFDKIJLE_02009 1.2e-60 lytE M LysM domain protein
BFDKIJLE_02010 4.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFDKIJLE_02011 8.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFDKIJLE_02012 4.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BFDKIJLE_02013 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFDKIJLE_02014 1.4e-129 S sequence-specific DNA binding
BFDKIJLE_02015 3.3e-231 ymfH S Peptidase M16
BFDKIJLE_02016 6.7e-229 ymfF S Peptidase M16
BFDKIJLE_02017 4.9e-58 yaaA S S4 domain protein YaaA
BFDKIJLE_02018 4.7e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFDKIJLE_02019 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BFDKIJLE_02020 2.5e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BFDKIJLE_02021 1.6e-152 yvjA S membrane
BFDKIJLE_02022 1.1e-305 ybiT S abc transporter atp-binding protein
BFDKIJLE_02023 0.0 XK27_10405 S Bacterial membrane protein YfhO
BFDKIJLE_02027 1.8e-119 yoaK S Protein of unknown function (DUF1275)
BFDKIJLE_02028 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFDKIJLE_02029 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
BFDKIJLE_02030 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)