ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEAGDMFB_00001 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEAGDMFB_00002 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEAGDMFB_00003 1.1e-29 yyzM S Protein conserved in bacteria
MEAGDMFB_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEAGDMFB_00005 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEAGDMFB_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEAGDMFB_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MEAGDMFB_00008 3e-60 divIC D Septum formation initiator
MEAGDMFB_00010 5.4e-234 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MEAGDMFB_00011 4.8e-235 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEAGDMFB_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEAGDMFB_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEAGDMFB_00026 2.6e-10
MEAGDMFB_00032 6.6e-92 mreC M Involved in formation and maintenance of cell shape
MEAGDMFB_00033 6.1e-83 mreD M rod shape-determining protein MreD
MEAGDMFB_00034 3.2e-84 usp 3.5.1.28 CBM50 S CHAP domain
MEAGDMFB_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAGDMFB_00036 1.9e-217 araT 2.6.1.1 E Aminotransferase
MEAGDMFB_00037 1e-139 recO L Involved in DNA repair and RecF pathway recombination
MEAGDMFB_00038 2.7e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEAGDMFB_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAGDMFB_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEAGDMFB_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAGDMFB_00042 1.1e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEAGDMFB_00043 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEAGDMFB_00044 9.9e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEAGDMFB_00045 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEAGDMFB_00046 1.3e-156 S CHAP domain
MEAGDMFB_00047 4.2e-239 purD 6.3.4.13 F Belongs to the GARS family
MEAGDMFB_00048 1e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEAGDMFB_00049 6.1e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEAGDMFB_00050 1.6e-82 1.1.1.169 H Ketopantoate reductase
MEAGDMFB_00051 4.7e-64 1.1.1.169 H Ketopantoate reductase
MEAGDMFB_00052 6.2e-32
MEAGDMFB_00053 7.4e-135 J Domain of unknown function (DUF4041)
MEAGDMFB_00054 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEAGDMFB_00056 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MEAGDMFB_00057 6.9e-69 argR K Regulates arginine biosynthesis genes
MEAGDMFB_00058 1.6e-55 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MEAGDMFB_00059 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEAGDMFB_00060 1e-78 S Protein of unknown function (DUF3021)
MEAGDMFB_00061 1.9e-69 K LytTr DNA-binding domain
MEAGDMFB_00063 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEAGDMFB_00065 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEAGDMFB_00066 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MEAGDMFB_00067 8.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
MEAGDMFB_00068 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEAGDMFB_00069 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MEAGDMFB_00075 2.6e-10
MEAGDMFB_00078 1.9e-07
MEAGDMFB_00083 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAGDMFB_00084 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MEAGDMFB_00085 5.5e-36 XK27_02060 S Transglycosylase associated protein
MEAGDMFB_00086 2.6e-71 badR K Transcriptional regulator, marr family
MEAGDMFB_00087 3.2e-95 S reductase
MEAGDMFB_00089 6.6e-287 ahpF O alkyl hydroperoxide reductase
MEAGDMFB_00090 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
MEAGDMFB_00091 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
MEAGDMFB_00092 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEAGDMFB_00093 1.6e-82 S Putative small multi-drug export protein
MEAGDMFB_00094 1.8e-75 ctsR K Belongs to the CtsR family
MEAGDMFB_00095 0.0 clpC O Belongs to the ClpA ClpB family
MEAGDMFB_00096 2.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEAGDMFB_00097 9e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEAGDMFB_00098 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEAGDMFB_00099 2.7e-140 S SseB protein N-terminal domain
MEAGDMFB_00100 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
MEAGDMFB_00102 9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEAGDMFB_00103 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEAGDMFB_00105 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAGDMFB_00106 1.3e-90 yacP S RNA-binding protein containing a PIN domain
MEAGDMFB_00107 7e-153 degV S DegV family
MEAGDMFB_00109 5.1e-22 K Transcriptional
MEAGDMFB_00110 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEAGDMFB_00111 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MEAGDMFB_00112 5e-181 L Belongs to the 'phage' integrase family
MEAGDMFB_00113 7.3e-29 S Helix-turn-helix domain
MEAGDMFB_00114 2.1e-73 S Psort location Cytoplasmic, score 8.87
MEAGDMFB_00115 2.3e-36 D FtsK/SpoIIIE family
MEAGDMFB_00118 5.5e-11 K Helix-turn-helix
MEAGDMFB_00120 7.6e-18
MEAGDMFB_00121 1.5e-29 K Helix-turn-helix domain
MEAGDMFB_00123 4.6e-149 srtB 3.4.22.70 S Sortase family
MEAGDMFB_00124 4.1e-231 capA M Bacterial capsule synthesis protein
MEAGDMFB_00125 6.1e-39 gcvR T UPF0237 protein
MEAGDMFB_00126 6.6e-243 XK27_08635 S UPF0210 protein
MEAGDMFB_00127 1.4e-130 ais G Phosphoglycerate mutase
MEAGDMFB_00128 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MEAGDMFB_00129 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
MEAGDMFB_00130 8.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEAGDMFB_00131 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEAGDMFB_00132 6e-303 dnaK O Heat shock 70 kDa protein
MEAGDMFB_00133 7.5e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
MEAGDMFB_00134 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEAGDMFB_00135 1.1e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEAGDMFB_00136 1.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MEAGDMFB_00137 7.4e-80 hmpT S cog cog4720
MEAGDMFB_00150 3.9e-87 sigH K DNA-templated transcription, initiation
MEAGDMFB_00151 3.1e-139 ykuT M mechanosensitive ion channel
MEAGDMFB_00152 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEAGDMFB_00153 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEAGDMFB_00154 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEAGDMFB_00155 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
MEAGDMFB_00156 3.5e-74 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MEAGDMFB_00157 1.1e-175 prmA J Ribosomal protein L11 methyltransferase
MEAGDMFB_00158 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEAGDMFB_00159 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MEAGDMFB_00160 9.1e-83 nrdI F Belongs to the NrdI family
MEAGDMFB_00161 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEAGDMFB_00162 4.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEAGDMFB_00163 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MEAGDMFB_00164 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MEAGDMFB_00165 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEAGDMFB_00166 2.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MEAGDMFB_00167 2.9e-194 yhjX P Major Facilitator
MEAGDMFB_00168 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEAGDMFB_00169 4.7e-84 V VanZ like family
MEAGDMFB_00170 9.9e-179 D nuclear chromosome segregation
MEAGDMFB_00171 2.2e-123 glnQ E abc transporter atp-binding protein
MEAGDMFB_00172 3.5e-272 glnP P ABC transporter
MEAGDMFB_00173 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEAGDMFB_00174 6.3e-18 S Protein of unknown function (DUF3021)
MEAGDMFB_00175 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEAGDMFB_00176 1.6e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
MEAGDMFB_00177 6.3e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MEAGDMFB_00178 2e-233 sufD O assembly protein SufD
MEAGDMFB_00179 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEAGDMFB_00180 2.7e-73 nifU C SUF system FeS assembly protein, NifU family
MEAGDMFB_00181 2.9e-273 sufB O assembly protein SufB
MEAGDMFB_00182 2.7e-26
MEAGDMFB_00183 7.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEAGDMFB_00184 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEAGDMFB_00185 2e-71 adcR K transcriptional
MEAGDMFB_00186 2.4e-135 adcC P ABC transporter, ATP-binding protein
MEAGDMFB_00187 6.6e-129 adcB P ABC transporter (Permease
MEAGDMFB_00188 8.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MEAGDMFB_00189 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_00190 7.6e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MEAGDMFB_00191 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
MEAGDMFB_00192 1.6e-149 Z012_04635 K sequence-specific DNA binding
MEAGDMFB_00193 2.3e-282 V ABC transporter
MEAGDMFB_00194 6.1e-126 yeeN K transcriptional regulatory protein
MEAGDMFB_00195 7.7e-47 yajC U protein transport
MEAGDMFB_00196 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEAGDMFB_00197 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
MEAGDMFB_00198 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MEAGDMFB_00199 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEAGDMFB_00200 0.0 WQ51_06230 S ABC transporter
MEAGDMFB_00201 1.4e-142 cmpC S abc transporter atp-binding protein
MEAGDMFB_00202 2.7e-40 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEAGDMFB_00203 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEAGDMFB_00205 1e-42
MEAGDMFB_00206 7.6e-55 S TM2 domain
MEAGDMFB_00207 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEAGDMFB_00208 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEAGDMFB_00209 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEAGDMFB_00210 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
MEAGDMFB_00211 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MEAGDMFB_00212 2e-72 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MEAGDMFB_00213 1.3e-145 cof S Sucrose-6F-phosphate phosphohydrolase
MEAGDMFB_00214 1.3e-134 glcR K transcriptional regulator (DeoR family)
MEAGDMFB_00215 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEAGDMFB_00216 7.6e-74 K helix_turn_helix multiple antibiotic resistance protein
MEAGDMFB_00217 5.9e-233 S COG1073 Hydrolases of the alpha beta superfamily
MEAGDMFB_00218 2.3e-151 cylA V abc transporter atp-binding protein
MEAGDMFB_00219 5.3e-129 cylB V ABC-2 type transporter
MEAGDMFB_00220 9e-75 K COG3279 Response regulator of the LytR AlgR family
MEAGDMFB_00221 2e-31 S Protein of unknown function (DUF3021)
MEAGDMFB_00222 5.8e-121 mta K Transcriptional
MEAGDMFB_00223 8.7e-122 yhcA V abc transporter atp-binding protein
MEAGDMFB_00224 1.2e-209 macB_2 V FtsX-like permease family
MEAGDMFB_00225 4.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEAGDMFB_00226 5.3e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEAGDMFB_00227 2.2e-73 yhaI S Protein of unknown function (DUF805)
MEAGDMFB_00228 2.6e-255 pepC 3.4.22.40 E aminopeptidase
MEAGDMFB_00229 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEAGDMFB_00230 1.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEAGDMFB_00231 5.8e-94 ypsA S Belongs to the UPF0398 family
MEAGDMFB_00232 2.1e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEAGDMFB_00233 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MEAGDMFB_00234 3.2e-281 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MEAGDMFB_00235 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MEAGDMFB_00236 4.8e-22
MEAGDMFB_00237 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MEAGDMFB_00238 3.2e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
MEAGDMFB_00239 1.1e-299 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEAGDMFB_00240 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEAGDMFB_00241 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAGDMFB_00242 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MEAGDMFB_00243 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAGDMFB_00244 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MEAGDMFB_00245 2.2e-101 ybhL S Belongs to the BI1 family
MEAGDMFB_00246 9.3e-12 ycdA S Domain of unknown function (DUF4352)
MEAGDMFB_00247 3.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEAGDMFB_00248 1.8e-90 K transcriptional regulator
MEAGDMFB_00249 1.6e-36 yneF S UPF0154 protein
MEAGDMFB_00250 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEAGDMFB_00251 3.6e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEAGDMFB_00252 5.1e-98 XK27_09740 S Phosphoesterase
MEAGDMFB_00253 8.3e-87 ykuL S CBS domain
MEAGDMFB_00254 4.2e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MEAGDMFB_00255 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEAGDMFB_00256 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEAGDMFB_00257 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEAGDMFB_00258 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
MEAGDMFB_00259 9.3e-259 trkH P Cation transport protein
MEAGDMFB_00260 5e-246 trkA P Potassium transporter peripheral membrane component
MEAGDMFB_00261 4.4e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEAGDMFB_00262 2.1e-86 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEAGDMFB_00263 4.9e-90 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MEAGDMFB_00264 2.5e-153 K sequence-specific DNA binding
MEAGDMFB_00265 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MEAGDMFB_00266 1.3e-54 yhaI L Membrane
MEAGDMFB_00267 3.3e-253 S Domain of unknown function (DUF4173)
MEAGDMFB_00268 1.2e-94 ureI S AmiS/UreI family transporter
MEAGDMFB_00269 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MEAGDMFB_00270 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MEAGDMFB_00271 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MEAGDMFB_00272 6.6e-78 ureE O enzyme active site formation
MEAGDMFB_00273 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MEAGDMFB_00274 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MEAGDMFB_00275 2e-157 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MEAGDMFB_00276 1.3e-176 cbiM P biosynthesis protein CbiM
MEAGDMFB_00277 3.2e-136 P cobalt transport protein
MEAGDMFB_00278 1.8e-130 cbiO P ABC transporter
MEAGDMFB_00279 1.8e-137 ET ABC transporter substrate-binding protein
MEAGDMFB_00280 1.9e-164 metQ M Belongs to the NlpA lipoprotein family
MEAGDMFB_00281 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MEAGDMFB_00282 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEAGDMFB_00283 8e-99 metI P ABC transporter (Permease
MEAGDMFB_00284 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MEAGDMFB_00285 3e-113 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MEAGDMFB_00286 5.8e-28 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MEAGDMFB_00287 6.7e-93 S UPF0397 protein
MEAGDMFB_00288 6.3e-307 ykoD P abc transporter atp-binding protein
MEAGDMFB_00289 4.5e-149 cbiQ P cobalt transport
MEAGDMFB_00290 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
MEAGDMFB_00291 4.2e-237 P COG0168 Trk-type K transport systems, membrane components
MEAGDMFB_00292 4.9e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MEAGDMFB_00293 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
MEAGDMFB_00294 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEAGDMFB_00295 2.3e-279 T PhoQ Sensor
MEAGDMFB_00296 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEAGDMFB_00297 1e-215 dnaB L Replication initiation and membrane attachment
MEAGDMFB_00298 4.4e-166 dnaI L Primosomal protein DnaI
MEAGDMFB_00299 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MEAGDMFB_00300 8.8e-113
MEAGDMFB_00301 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEAGDMFB_00302 2.5e-62 manO S protein conserved in bacteria
MEAGDMFB_00303 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
MEAGDMFB_00304 2e-117 manM G pts system
MEAGDMFB_00305 4.9e-174 manL 2.7.1.191 G pts system
MEAGDMFB_00306 2e-67 manO S Protein conserved in bacteria
MEAGDMFB_00307 2.7e-163 manN G PTS system mannose fructose sorbose family IID component
MEAGDMFB_00308 4.7e-135 manY G pts system
MEAGDMFB_00309 8.1e-169 manL 2.7.1.191 G pts system
MEAGDMFB_00310 9.3e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MEAGDMFB_00311 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MEAGDMFB_00312 6.2e-247 pbuO S permease
MEAGDMFB_00313 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MEAGDMFB_00314 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
MEAGDMFB_00315 9.8e-188 brpA K Transcriptional
MEAGDMFB_00316 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
MEAGDMFB_00317 7.1e-196 nusA K Participates in both transcription termination and antitermination
MEAGDMFB_00318 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MEAGDMFB_00319 8e-42 ylxQ J ribosomal protein
MEAGDMFB_00320 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEAGDMFB_00321 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEAGDMFB_00322 8.5e-99 yvdD 3.2.2.10 S Belongs to the LOG family
MEAGDMFB_00323 5.1e-189 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MEAGDMFB_00324 2.2e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEAGDMFB_00325 4.4e-278 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MEAGDMFB_00326 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MEAGDMFB_00327 3e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
MEAGDMFB_00328 4e-220 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MEAGDMFB_00329 3.5e-305 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
MEAGDMFB_00330 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MEAGDMFB_00331 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEAGDMFB_00332 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEAGDMFB_00333 4.1e-72 ylbF S Belongs to the UPF0342 family
MEAGDMFB_00334 2.1e-45 ylbG S UPF0298 protein
MEAGDMFB_00335 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MEAGDMFB_00336 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
MEAGDMFB_00337 3.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MEAGDMFB_00338 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MEAGDMFB_00339 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MEAGDMFB_00340 1.3e-111 acuB S CBS domain
MEAGDMFB_00341 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEAGDMFB_00342 2.2e-108 yvyE 3.4.13.9 S YigZ family
MEAGDMFB_00343 1.7e-243 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MEAGDMFB_00344 5.3e-84 comFC K competence protein
MEAGDMFB_00345 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEAGDMFB_00353 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
MEAGDMFB_00354 1.4e-102 S Domain of unknown function (DUF1803)
MEAGDMFB_00355 7.8e-102 ygaC J Belongs to the UPF0374 family
MEAGDMFB_00356 3.1e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
MEAGDMFB_00357 1.7e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAGDMFB_00358 2e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
MEAGDMFB_00359 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
MEAGDMFB_00360 8.1e-114 S HAD hydrolase, family IA, variant 3
MEAGDMFB_00361 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MEAGDMFB_00362 5.2e-72 marR K Transcriptional regulator, MarR family
MEAGDMFB_00363 7e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEAGDMFB_00364 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAGDMFB_00365 7.5e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MEAGDMFB_00366 1.2e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MEAGDMFB_00367 1.8e-125 IQ reductase
MEAGDMFB_00368 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEAGDMFB_00369 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEAGDMFB_00370 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEAGDMFB_00371 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MEAGDMFB_00372 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEAGDMFB_00373 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MEAGDMFB_00374 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEAGDMFB_00375 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
MEAGDMFB_00376 4.1e-125 fruR K transcriptional
MEAGDMFB_00377 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MEAGDMFB_00378 0.0 fruA 2.7.1.202 G phosphotransferase system
MEAGDMFB_00379 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MEAGDMFB_00380 7.6e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEAGDMFB_00382 8.8e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MEAGDMFB_00383 7.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEAGDMFB_00384 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MEAGDMFB_00385 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MEAGDMFB_00386 1.6e-94 2.3.1.128 K acetyltransferase
MEAGDMFB_00387 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEAGDMFB_00388 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MEAGDMFB_00389 4.4e-129 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEAGDMFB_00391 2.6e-13
MEAGDMFB_00392 5e-63 WQ51_03320 S cog cog4835
MEAGDMFB_00393 1.5e-147 XK27_08360 S EDD domain protein, DegV family
MEAGDMFB_00394 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEAGDMFB_00395 1.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEAGDMFB_00396 0.0 yfmR S abc transporter atp-binding protein
MEAGDMFB_00397 1.3e-26 U response to pH
MEAGDMFB_00398 5.3e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MEAGDMFB_00399 1.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MEAGDMFB_00400 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MEAGDMFB_00401 5.1e-277 S Psort location CytoplasmicMembrane, score
MEAGDMFB_00402 6.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEAGDMFB_00403 3.3e-74 K DNA-binding transcription factor activity
MEAGDMFB_00404 0.0 lmrA1 V abc transporter atp-binding protein
MEAGDMFB_00405 0.0 lmrA2 V abc transporter atp-binding protein
MEAGDMFB_00406 6.7e-113 K Acetyltransferase (GNAT) family
MEAGDMFB_00407 1.3e-111 2.7.6.5 S Region found in RelA / SpoT proteins
MEAGDMFB_00408 1.7e-117 T response regulator
MEAGDMFB_00409 1.1e-215 sptS 2.7.13.3 T Histidine kinase
MEAGDMFB_00410 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEAGDMFB_00411 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEAGDMFB_00412 5e-159 cvfB S Protein conserved in bacteria
MEAGDMFB_00413 3.7e-34 yozE S Belongs to the UPF0346 family
MEAGDMFB_00414 1.3e-126 sip M LysM domain protein
MEAGDMFB_00415 2.6e-189 phoH T phosphate starvation-inducible protein PhoH
MEAGDMFB_00419 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEAGDMFB_00420 7.6e-160 S reductase
MEAGDMFB_00421 4.7e-168 K transcriptional regulator (lysR family)
MEAGDMFB_00422 5.5e-106 S CAAX amino terminal protease family protein
MEAGDMFB_00423 8.7e-260 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MEAGDMFB_00424 3.1e-165 coiA 3.6.4.12 S Competence protein
MEAGDMFB_00425 0.0 pepF E oligoendopeptidase F
MEAGDMFB_00426 8.5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
MEAGDMFB_00427 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
MEAGDMFB_00428 1.1e-164 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MEAGDMFB_00429 2.4e-81 yxjI S LURP-one-related
MEAGDMFB_00430 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEAGDMFB_00431 3.6e-163 K sequence-specific DNA binding
MEAGDMFB_00432 7.7e-09
MEAGDMFB_00434 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MEAGDMFB_00435 1.4e-136 agrA KT response regulator
MEAGDMFB_00437 2.4e-133 agrA KT phosphorelay signal transduction system
MEAGDMFB_00438 4.6e-228 2.7.13.3 T GHKL domain
MEAGDMFB_00439 1.5e-14
MEAGDMFB_00440 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
MEAGDMFB_00441 1.2e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MEAGDMFB_00442 2.6e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MEAGDMFB_00443 5.2e-179 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEAGDMFB_00444 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEAGDMFB_00445 8.7e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MEAGDMFB_00446 4.6e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MEAGDMFB_00447 2.7e-128 yxkH G deacetylase
MEAGDMFB_00448 2e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MEAGDMFB_00449 2.7e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEAGDMFB_00450 1.5e-145 rarD S Transporter
MEAGDMFB_00451 4.1e-14 T peptidase
MEAGDMFB_00452 3e-14 coiA 3.6.4.12 S Competence protein
MEAGDMFB_00453 4.2e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MEAGDMFB_00454 6.9e-101 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
MEAGDMFB_00455 2e-95 F Shikimate kinase
MEAGDMFB_00456 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEAGDMFB_00457 2.1e-173 L DNA restriction-modification system
MEAGDMFB_00458 0.0 T Histidine kinase
MEAGDMFB_00459 2.2e-95
MEAGDMFB_00460 3.3e-107 L HNH endonuclease
MEAGDMFB_00461 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAGDMFB_00462 6e-118 atpB C it plays a direct role in the translocation of protons across the membrane
MEAGDMFB_00463 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEAGDMFB_00464 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAGDMFB_00465 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEAGDMFB_00466 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEAGDMFB_00467 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEAGDMFB_00468 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEAGDMFB_00469 1.6e-217 ftsW D Belongs to the SEDS family
MEAGDMFB_00470 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEAGDMFB_00471 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEAGDMFB_00472 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEAGDMFB_00474 6.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEAGDMFB_00475 1.7e-159 holB 2.7.7.7 L dna polymerase iii
MEAGDMFB_00476 5.2e-134 yaaT S stage 0 sporulation protein
MEAGDMFB_00477 1.2e-54 yabA L Involved in initiation control of chromosome replication
MEAGDMFB_00478 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEAGDMFB_00479 2.3e-226 amt P Ammonium Transporter
MEAGDMFB_00480 1.9e-53 glnB K Belongs to the P(II) protein family
MEAGDMFB_00481 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
MEAGDMFB_00482 1.7e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MEAGDMFB_00483 2e-75 S Bacterial inner membrane protein
MEAGDMFB_00484 2.6e-112 3.4.17.14, 3.5.1.28 NU amidase activity
MEAGDMFB_00485 3.5e-294 nptA P COG1283 Na phosphate symporter
MEAGDMFB_00486 4.9e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEAGDMFB_00487 7.8e-222 S membrane
MEAGDMFB_00488 2.5e-67 S Glutathione-dependent formaldehyde-activating
MEAGDMFB_00489 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MEAGDMFB_00490 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEAGDMFB_00491 1.7e-38 ynzC S UPF0291 protein
MEAGDMFB_00492 6e-255 cycA E permease
MEAGDMFB_00493 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEAGDMFB_00494 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_00495 1.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEAGDMFB_00499 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
MEAGDMFB_00500 1.4e-56 S ABC-2 type transporter
MEAGDMFB_00501 1.8e-96
MEAGDMFB_00503 4.7e-168 fhuR K transcriptional regulator (lysR family)
MEAGDMFB_00504 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEAGDMFB_00505 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEAGDMFB_00506 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEAGDMFB_00507 4.7e-222 pyrP F uracil Permease
MEAGDMFB_00508 8.6e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEAGDMFB_00509 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MEAGDMFB_00510 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MEAGDMFB_00511 4.7e-121 2.1.1.223 S Putative SAM-dependent methyltransferase
MEAGDMFB_00512 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEAGDMFB_00513 3.1e-122 macB V ABC transporter, ATP-binding protein
MEAGDMFB_00514 2e-201 V permease protein
MEAGDMFB_00515 3.3e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEAGDMFB_00516 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEAGDMFB_00517 0.0 mdlB V abc transporter atp-binding protein
MEAGDMFB_00518 0.0 lmrA V abc transporter atp-binding protein
MEAGDMFB_00519 7.3e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEAGDMFB_00520 1.2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEAGDMFB_00521 1.8e-197 yceA S Belongs to the UPF0176 family
MEAGDMFB_00522 1.6e-28 XK27_00085 K Transcriptional
MEAGDMFB_00523 2.1e-24
MEAGDMFB_00524 1.4e-136 deoD_1 2.4.2.3 F Phosphorylase superfamily
MEAGDMFB_00525 3.9e-114 S VIT family
MEAGDMFB_00526 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEAGDMFB_00527 7.7e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MEAGDMFB_00528 2.2e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MEAGDMFB_00530 1.3e-124 E Alpha beta hydrolase
MEAGDMFB_00531 2.8e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MEAGDMFB_00532 3.8e-138 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MEAGDMFB_00533 2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MEAGDMFB_00534 1.2e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MEAGDMFB_00535 6.8e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEAGDMFB_00536 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MEAGDMFB_00537 1.3e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEAGDMFB_00538 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MEAGDMFB_00539 1.1e-24
MEAGDMFB_00540 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEAGDMFB_00541 0.0 U protein secretion
MEAGDMFB_00542 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MEAGDMFB_00543 8.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MEAGDMFB_00544 1.1e-12
MEAGDMFB_00545 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEAGDMFB_00546 1.4e-162 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEAGDMFB_00547 7.2e-200 S Protein of unknown function (DUF3114)
MEAGDMFB_00548 4.1e-29 pspC KT PspC domain protein
MEAGDMFB_00549 5.2e-119 yqfA K protein, Hemolysin III
MEAGDMFB_00550 3e-78 K hmm pf08876
MEAGDMFB_00551 1e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MEAGDMFB_00552 1.1e-209 mvaS 2.3.3.10 I synthase
MEAGDMFB_00553 1.1e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEAGDMFB_00554 4.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEAGDMFB_00555 9.7e-22
MEAGDMFB_00556 1.3e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEAGDMFB_00557 3.3e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
MEAGDMFB_00558 3.7e-249 mmuP E amino acid
MEAGDMFB_00559 6.7e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MEAGDMFB_00560 2.2e-30 S Domain of unknown function (DUF1912)
MEAGDMFB_00561 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
MEAGDMFB_00562 7.4e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEAGDMFB_00563 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAGDMFB_00564 4.2e-147 aadK G adenylyltransferase
MEAGDMFB_00565 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAGDMFB_00566 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
MEAGDMFB_00567 3.7e-16 S Protein of unknown function (DUF2969)
MEAGDMFB_00570 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
MEAGDMFB_00573 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
MEAGDMFB_00574 2.9e-117 M Pfam SNARE associated Golgi protein
MEAGDMFB_00575 5e-229 murN 2.3.2.16 V FemAB family
MEAGDMFB_00576 5.8e-172 S oxidoreductase
MEAGDMFB_00577 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
MEAGDMFB_00578 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MEAGDMFB_00579 0.0 clpE O Belongs to the ClpA ClpB family
MEAGDMFB_00580 1.8e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEAGDMFB_00581 1e-34 ykuJ S protein conserved in bacteria
MEAGDMFB_00582 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MEAGDMFB_00583 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_00584 1.6e-77 feoA P FeoA domain protein
MEAGDMFB_00585 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MEAGDMFB_00586 3.3e-07
MEAGDMFB_00587 1.5e-149 I Alpha/beta hydrolase family
MEAGDMFB_00588 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEAGDMFB_00589 9.5e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEAGDMFB_00590 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MEAGDMFB_00591 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEAGDMFB_00592 2e-144 licT K antiterminator
MEAGDMFB_00593 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEAGDMFB_00594 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MEAGDMFB_00595 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEAGDMFB_00596 7.4e-144 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEAGDMFB_00597 7.6e-90 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEAGDMFB_00598 1.9e-220 mdtG EGP Major facilitator Superfamily
MEAGDMFB_00599 2e-33 secG U Preprotein translocase subunit SecG
MEAGDMFB_00600 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEAGDMFB_00601 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEAGDMFB_00602 2.4e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEAGDMFB_00603 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MEAGDMFB_00604 4.9e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MEAGDMFB_00605 3.2e-181 ccpA K Catabolite control protein A
MEAGDMFB_00606 2.9e-201 yyaQ S YjbR
MEAGDMFB_00607 1.1e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEAGDMFB_00608 3.9e-78 yueI S Protein of unknown function (DUF1694)
MEAGDMFB_00609 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEAGDMFB_00610 7.4e-206 S Phage integrase family
MEAGDMFB_00611 4.3e-17 E Pfam:DUF955
MEAGDMFB_00614 7.4e-30 S sequence-specific DNA binding
MEAGDMFB_00615 3.9e-21 S Protein of unknown function (DUF739)
MEAGDMFB_00618 2.2e-24
MEAGDMFB_00620 1.2e-79 M Pilin isopeptide linkage domain protein
MEAGDMFB_00621 6.9e-176 D AAA domain
MEAGDMFB_00622 9e-129 S AAA domain
MEAGDMFB_00623 2.3e-67
MEAGDMFB_00624 3.2e-268 L helicase
MEAGDMFB_00625 0.0 L Primase C terminal 2 (PriCT-2)
MEAGDMFB_00626 4e-16
MEAGDMFB_00627 1.7e-56 rusA L crossover junction endodeoxyribonuclease RusA
MEAGDMFB_00630 1.7e-10
MEAGDMFB_00634 1.3e-12 S Protein of unknown function (DUF1642)
MEAGDMFB_00635 2e-46
MEAGDMFB_00637 3.8e-16 S YopX protein
MEAGDMFB_00640 2.6e-24 L DNA packaging
MEAGDMFB_00641 1.7e-222 S Pfam:Terminase_3C
MEAGDMFB_00642 2.2e-263 S Phage portal protein, SPP1 Gp6-like
MEAGDMFB_00643 2.5e-124 M Phage minor capsid protein 2
MEAGDMFB_00644 4.6e-74 S Phage minor structural protein GP20
MEAGDMFB_00645 2.3e-140 S peptidase activity
MEAGDMFB_00647 4.7e-56
MEAGDMFB_00648 2.4e-24 S Minor capsid protein
MEAGDMFB_00649 3.1e-23 S Minor capsid protein
MEAGDMFB_00650 1.5e-52 S Minor capsid protein from bacteriophage
MEAGDMFB_00651 3e-75
MEAGDMFB_00652 6.4e-23
MEAGDMFB_00653 6.9e-86 S Bacteriophage Gp15 protein
MEAGDMFB_00654 5.1e-242 S transmembrane transport
MEAGDMFB_00655 2.7e-105
MEAGDMFB_00656 9.5e-179 S peptidoglycan catabolic process
MEAGDMFB_00657 1.7e-17 3.1.1.5 E GDSL-like Lipase/Acylhydrolase family
MEAGDMFB_00658 3.3e-58 S Pfam:Phage_holin_4_1
MEAGDMFB_00659 9e-23 S COG5546 Small integral membrane protein
MEAGDMFB_00660 1.6e-07
MEAGDMFB_00663 1.6e-109 M Bacteriophage peptidoglycan hydrolase
MEAGDMFB_00664 4.6e-25 WQ51_00785
MEAGDMFB_00665 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MEAGDMFB_00666 3e-215 ywbD 2.1.1.191 J Methyltransferase
MEAGDMFB_00667 4.9e-117 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEAGDMFB_00668 1.3e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEAGDMFB_00669 3.8e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEAGDMFB_00670 8.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEAGDMFB_00671 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MEAGDMFB_00672 4.2e-53 yheA S Belongs to the UPF0342 family
MEAGDMFB_00673 3.7e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEAGDMFB_00674 2.1e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEAGDMFB_00675 4.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEAGDMFB_00676 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
MEAGDMFB_00677 2.6e-245 msrR K Transcriptional regulator
MEAGDMFB_00678 3.4e-142 ydiA P C4-dicarboxylate transporter malic acid transport
MEAGDMFB_00679 5.5e-200 I acyl-CoA dehydrogenase
MEAGDMFB_00680 2e-97 mip S hydroperoxide reductase activity
MEAGDMFB_00681 3.2e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAGDMFB_00682 4.3e-22
MEAGDMFB_00683 2e-217 EGP Transmembrane secretion effector
MEAGDMFB_00684 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
MEAGDMFB_00685 1.1e-49
MEAGDMFB_00686 8.7e-60
MEAGDMFB_00687 5.9e-55
MEAGDMFB_00688 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEAGDMFB_00689 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
MEAGDMFB_00690 9.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
MEAGDMFB_00691 1.6e-61 smtB K Transcriptional regulator
MEAGDMFB_00692 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MEAGDMFB_00694 1.8e-139 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEAGDMFB_00695 3.1e-141 S Domain of unknown function (DUF4336)
MEAGDMFB_00696 7.7e-203 yeaN P transporter
MEAGDMFB_00697 5.8e-152 yitS S EDD domain protein, DegV family
MEAGDMFB_00698 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
MEAGDMFB_00699 8.6e-108 cutC P Participates in the control of copper homeostasis
MEAGDMFB_00701 5.4e-21 S Domain of unknown function (DUF4767)
MEAGDMFB_00702 1.6e-157 S Domain of unknown function (DUF4300)
MEAGDMFB_00703 8.3e-126 V CAAX protease self-immunity
MEAGDMFB_00704 4.6e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEAGDMFB_00705 1.1e-133 fecE 3.6.3.34 HP ABC transporter
MEAGDMFB_00706 2.6e-175 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MEAGDMFB_00707 5.5e-124 ybbA S Putative esterase
MEAGDMFB_00708 1.3e-81 Q Methyltransferase domain
MEAGDMFB_00709 8.5e-78 K TetR family transcriptional regulator
MEAGDMFB_00710 5.8e-49
MEAGDMFB_00711 1e-120 S CAAX protease self-immunity
MEAGDMFB_00712 1.5e-10
MEAGDMFB_00713 8.4e-19 S Bacterial lipoprotein
MEAGDMFB_00714 5.4e-60 S Protein of unknown function (DUF1722)
MEAGDMFB_00715 2.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
MEAGDMFB_00717 3e-49
MEAGDMFB_00718 8.4e-119 estA E GDSL-like Lipase/Acylhydrolase
MEAGDMFB_00719 1.2e-101
MEAGDMFB_00720 2.1e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
MEAGDMFB_00721 9.9e-149 ycgQ S TIGR03943 family
MEAGDMFB_00722 1.9e-156 XK27_03015 S permease
MEAGDMFB_00724 0.0 yhgF K Transcriptional accessory protein
MEAGDMFB_00725 8.7e-83 ydcK S Belongs to the SprT family
MEAGDMFB_00726 1.9e-88 L COG1943 Transposase and inactivated derivatives
MEAGDMFB_00727 2.2e-41 pspC KT PspC domain
MEAGDMFB_00728 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEAGDMFB_00729 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEAGDMFB_00730 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEAGDMFB_00731 3e-67 ytxH S General stress protein
MEAGDMFB_00733 1.5e-177 yegQ O Peptidase U32
MEAGDMFB_00734 1.7e-251 yegQ O Peptidase U32
MEAGDMFB_00735 1.1e-87 bioY S biotin synthase
MEAGDMFB_00737 1.1e-33 XK27_12190 S protein conserved in bacteria
MEAGDMFB_00738 1.3e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MEAGDMFB_00739 6.7e-13
MEAGDMFB_00740 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
MEAGDMFB_00741 0.0 L helicase
MEAGDMFB_00742 2.9e-11
MEAGDMFB_00743 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEAGDMFB_00744 4.3e-138 M LysM domain
MEAGDMFB_00745 8.4e-23
MEAGDMFB_00746 5.2e-175 S hydrolase
MEAGDMFB_00748 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MEAGDMFB_00749 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEAGDMFB_00750 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MEAGDMFB_00751 1.3e-26 P Hemerythrin HHE cation binding domain protein
MEAGDMFB_00752 2.8e-154 5.2.1.8 G hydrolase
MEAGDMFB_00753 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEAGDMFB_00754 9e-196 MA20_36090 S Protein of unknown function (DUF2974)
MEAGDMFB_00755 2.2e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAGDMFB_00756 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
MEAGDMFB_00757 1.4e-271 hsdM 2.1.1.72 V type I restriction-modification system
MEAGDMFB_00758 1.7e-99 3.1.21.3 L Type I restriction modification DNA specificity domain
MEAGDMFB_00759 2.1e-106
MEAGDMFB_00760 1.4e-133
MEAGDMFB_00761 1.6e-52
MEAGDMFB_00762 3e-193 higA K Pfam:DUF955
MEAGDMFB_00763 3.9e-133 S double-stranded DNA endodeoxyribonuclease activity
MEAGDMFB_00764 0.0 M Right handed beta helix region
MEAGDMFB_00765 3e-171 spd F DNA RNA non-specific endonuclease
MEAGDMFB_00766 2.2e-91 lemA S LemA family
MEAGDMFB_00767 1.3e-133 htpX O Belongs to the peptidase M48B family
MEAGDMFB_00768 2.6e-115 sirR K iron dependent repressor
MEAGDMFB_00769 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
MEAGDMFB_00770 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
MEAGDMFB_00771 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
MEAGDMFB_00772 4.7e-74 S Psort location CytoplasmicMembrane, score
MEAGDMFB_00773 8.1e-64 S Domain of unknown function (DUF4430)
MEAGDMFB_00774 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MEAGDMFB_00775 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
MEAGDMFB_00776 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MEAGDMFB_00777 6e-170 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MEAGDMFB_00778 6.6e-103 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MEAGDMFB_00779 1.1e-89 dps P Belongs to the Dps family
MEAGDMFB_00780 3.4e-79 perR P Belongs to the Fur family
MEAGDMFB_00781 7.1e-27 yqgQ S protein conserved in bacteria
MEAGDMFB_00782 1e-176 glk 2.7.1.2 G Glucokinase
MEAGDMFB_00783 0.0 typA T GTP-binding protein TypA
MEAGDMFB_00785 3.9e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEAGDMFB_00786 1.2e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEAGDMFB_00787 1.5e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEAGDMFB_00788 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEAGDMFB_00789 7.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEAGDMFB_00790 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEAGDMFB_00791 1.8e-99 sepF D cell septum assembly
MEAGDMFB_00792 2.9e-30 yggT D integral membrane protein
MEAGDMFB_00793 3.2e-62 ylmH S conserved protein, contains S4-like domain
MEAGDMFB_00794 3.3e-56 ylmH S conserved protein, contains S4-like domain
MEAGDMFB_00795 8.4e-138 divIVA D Cell division initiation protein
MEAGDMFB_00796 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEAGDMFB_00797 2.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAGDMFB_00798 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAGDMFB_00799 2.2e-34 nrdH O Glutaredoxin
MEAGDMFB_00800 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MEAGDMFB_00801 7.4e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
MEAGDMFB_00802 1.1e-220 icd 1.1.1.42 C Isocitrate dehydrogenase
MEAGDMFB_00803 3e-38 ptsH G phosphocarrier protein Hpr
MEAGDMFB_00804 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEAGDMFB_00805 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MEAGDMFB_00806 3.7e-159 XK27_05670 S Putative esterase
MEAGDMFB_00807 3e-152 XK27_05675 S Esterase
MEAGDMFB_00808 1.6e-224 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
MEAGDMFB_00809 6.3e-175 yfmL 3.6.4.13 L DEAD DEAH box helicase
MEAGDMFB_00810 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MEAGDMFB_00811 0.0 uup S abc transporter atp-binding protein
MEAGDMFB_00812 1.6e-39 MA20_06245 S yiaA/B two helix domain
MEAGDMFB_00813 1.7e-131 pip 1.11.1.10 S Alpha beta hydrolase
MEAGDMFB_00814 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEAGDMFB_00815 1.5e-149 cobQ S glutamine amidotransferase
MEAGDMFB_00816 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MEAGDMFB_00817 1.4e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEAGDMFB_00818 1.1e-162 ybbR S Protein conserved in bacteria
MEAGDMFB_00819 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEAGDMFB_00820 1.3e-64 gtrA S GtrA-like protein
MEAGDMFB_00821 1.7e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
MEAGDMFB_00822 3.2e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEAGDMFB_00823 4e-145 zupT P Mediates zinc uptake. May also transport other divalent cations
MEAGDMFB_00824 1.4e-198 yurR 1.4.5.1 E oxidoreductase
MEAGDMFB_00825 3.6e-257 S phospholipase Carboxylesterase
MEAGDMFB_00826 1.2e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEAGDMFB_00827 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MEAGDMFB_00828 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEAGDMFB_00830 4.9e-30 KT response to antibiotic
MEAGDMFB_00831 6.5e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
MEAGDMFB_00832 3.4e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
MEAGDMFB_00833 2.1e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEAGDMFB_00834 1.5e-115 ylfI S tigr01906
MEAGDMFB_00835 3.2e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MEAGDMFB_00836 1e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MEAGDMFB_00837 4.9e-61 XK27_08085
MEAGDMFB_00838 1.6e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEAGDMFB_00839 2.1e-177 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MEAGDMFB_00840 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MEAGDMFB_00841 9.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEAGDMFB_00842 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MEAGDMFB_00843 5.2e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEAGDMFB_00844 7e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MEAGDMFB_00845 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEAGDMFB_00846 8.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEAGDMFB_00847 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MEAGDMFB_00849 3.8e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
MEAGDMFB_00850 2e-143 P molecular chaperone
MEAGDMFB_00851 6.3e-94 S Carbohydrate-binding domain-containing protein Cthe_2159
MEAGDMFB_00852 5.7e-178 XK27_08075 M glycosyl transferase family 2
MEAGDMFB_00853 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_00854 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_00855 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_00856 2.4e-235 rodA D Belongs to the SEDS family
MEAGDMFB_00857 1.2e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEAGDMFB_00858 5.3e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MEAGDMFB_00859 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEAGDMFB_00860 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAGDMFB_00861 2.6e-21 Q Methyltransferase domain
MEAGDMFB_00862 8.3e-64 GnaT 2.5.1.16 K acetyltransferase
MEAGDMFB_00863 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MEAGDMFB_00864 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEAGDMFB_00865 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEAGDMFB_00866 1.3e-125 dnaD
MEAGDMFB_00867 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEAGDMFB_00869 3.9e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAGDMFB_00870 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAGDMFB_00871 2.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEAGDMFB_00872 3.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MEAGDMFB_00873 7e-72 argR K Regulates arginine biosynthesis genes
MEAGDMFB_00874 2.3e-301 recN L May be involved in recombinational repair of damaged DNA
MEAGDMFB_00875 2.9e-143 DegV S DegV family
MEAGDMFB_00876 6.6e-159 ypmR E COG2755 Lysophospholipase L1 and related esterases
MEAGDMFB_00877 2e-95 ypmS S Protein conserved in bacteria
MEAGDMFB_00878 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEAGDMFB_00880 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MEAGDMFB_00881 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEAGDMFB_00882 5.5e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEAGDMFB_00883 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEAGDMFB_00884 2.1e-37 ysdA L Membrane
MEAGDMFB_00885 5.2e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEAGDMFB_00886 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEAGDMFB_00887 0.0 dnaE 2.7.7.7 L DNA polymerase
MEAGDMFB_00888 1.1e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEAGDMFB_00889 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MEAGDMFB_00890 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
MEAGDMFB_00891 1.7e-18 S Domain of unknown function (DUF4649)
MEAGDMFB_00892 6.2e-177 XK27_08835 S ABC transporter substrate binding protein
MEAGDMFB_00893 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MEAGDMFB_00894 2e-135 XK27_08845 S abc transporter atp-binding protein
MEAGDMFB_00895 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAGDMFB_00896 4.7e-148 estA CE1 S Esterase
MEAGDMFB_00897 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MEAGDMFB_00898 2.2e-18 XK27_08880
MEAGDMFB_00899 1e-75 fld C Flavodoxin
MEAGDMFB_00900 3.5e-280 clcA P Chloride transporter, ClC family
MEAGDMFB_00901 4.2e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MEAGDMFB_00902 2.5e-212 XK27_05110 P Chloride transporter ClC family
MEAGDMFB_00903 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEAGDMFB_00906 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
MEAGDMFB_00907 4.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEAGDMFB_00908 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
MEAGDMFB_00909 3.9e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAGDMFB_00910 1.2e-169 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEAGDMFB_00911 7.8e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEAGDMFB_00912 4.6e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
MEAGDMFB_00913 5.5e-148
MEAGDMFB_00914 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MEAGDMFB_00915 2.3e-270 pelF GT4 M Domain of unknown function (DUF3492)
MEAGDMFB_00916 1.1e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
MEAGDMFB_00917 1e-222 cotH M CotH kinase protein
MEAGDMFB_00918 3e-96 P VTC domain
MEAGDMFB_00919 2.7e-83 S membrane
MEAGDMFB_00920 7e-134 G Domain of unknown function (DUF4832)
MEAGDMFB_00921 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEAGDMFB_00923 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEAGDMFB_00924 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
MEAGDMFB_00925 1.9e-153 endA F DNA RNA non-specific endonuclease
MEAGDMFB_00926 1.1e-110 tcyB_2 P ABC transporter (permease)
MEAGDMFB_00927 2.4e-142 peb1A ET Belongs to the bacterial solute-binding protein 3 family
MEAGDMFB_00928 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_00929 2.3e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MEAGDMFB_00930 7.9e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_00931 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEAGDMFB_00932 8.1e-233 vicK 2.7.13.3 T Histidine kinase
MEAGDMFB_00933 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MEAGDMFB_00934 1.5e-56 S Protein of unknown function (DUF454)
MEAGDMFB_00935 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MEAGDMFB_00936 7.8e-146 yidA S hydrolases of the HAD superfamily
MEAGDMFB_00937 1.4e-137 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
MEAGDMFB_00938 5.1e-131 XK27_00120 2.4.2.3 F Phosphorylase superfamily
MEAGDMFB_00939 1.2e-67 ywiB S Domain of unknown function (DUF1934)
MEAGDMFB_00940 0.0 pacL 3.6.3.8 P cation transport ATPase
MEAGDMFB_00941 1.1e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MEAGDMFB_00942 5.4e-158 yjjH S Calcineurin-like phosphoesterase
MEAGDMFB_00943 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MEAGDMFB_00944 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEAGDMFB_00945 3.2e-124 ftsE D cell division ATP-binding protein FtsE
MEAGDMFB_00946 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MEAGDMFB_00947 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MEAGDMFB_00948 9.5e-177 yubA S permease
MEAGDMFB_00949 8.3e-224 G COG0457 FOG TPR repeat
MEAGDMFB_00950 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MEAGDMFB_00951 4.6e-36 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MEAGDMFB_00952 1.6e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MEAGDMFB_00953 8.6e-87 ebsA S Family of unknown function (DUF5322)
MEAGDMFB_00954 5.6e-17 M LysM domain
MEAGDMFB_00955 1.4e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MEAGDMFB_00956 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEAGDMFB_00957 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MEAGDMFB_00958 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEAGDMFB_00959 2.1e-74 XK27_03610 K Gnat family
MEAGDMFB_00960 1.8e-87 yybC
MEAGDMFB_00961 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MEAGDMFB_00962 1.5e-266 pepV 3.5.1.18 E Dipeptidase
MEAGDMFB_00963 1.4e-107 ung2 3.2.2.27 L Uracil-DNA glycosylase
MEAGDMFB_00964 1.4e-224 V Glucan-binding protein C
MEAGDMFB_00966 4.7e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEAGDMFB_00967 7.5e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MEAGDMFB_00968 3.2e-95 S Protein of unknown function (DUF1697)
MEAGDMFB_00969 1.6e-143 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MEAGDMFB_00970 8.1e-54 S LemA family
MEAGDMFB_00971 1e-160 clcA_2 P chloride
MEAGDMFB_00972 1.8e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
MEAGDMFB_00973 3.7e-131 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MEAGDMFB_00974 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MEAGDMFB_00975 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MEAGDMFB_00976 3.5e-110 cps4C M biosynthesis protein
MEAGDMFB_00977 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
MEAGDMFB_00978 1.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MEAGDMFB_00979 4.8e-221 rgpAc GT4 M group 1 family protein
MEAGDMFB_00980 3.4e-211 wcoF M Glycosyltransferase, group 1 family protein
MEAGDMFB_00981 7.1e-118 Z012_10770 M Domain of unknown function (DUF1919)
MEAGDMFB_00982 6.5e-163 M Glycosyltransferase, group 2 family protein
MEAGDMFB_00983 1.2e-153 M Glycosyltransferase like family 2
MEAGDMFB_00984 1.5e-174
MEAGDMFB_00985 7e-251 epsU S Polysaccharide biosynthesis protein
MEAGDMFB_00986 3.4e-159 S Acyltransferase family
MEAGDMFB_00987 1.4e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
MEAGDMFB_00988 3e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MEAGDMFB_00989 9.1e-187 wbbI M transferase activity, transferring glycosyl groups
MEAGDMFB_00991 4.8e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MEAGDMFB_00992 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
MEAGDMFB_00993 1.7e-108 G Belongs to the phosphoglycerate mutase family
MEAGDMFB_00994 3.6e-108 G Belongs to the phosphoglycerate mutase family
MEAGDMFB_00995 2.3e-196 S hmm pf01594
MEAGDMFB_00996 6.2e-287 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAGDMFB_00997 4.9e-39 S granule-associated protein
MEAGDMFB_00998 5.2e-287 S unusual protein kinase
MEAGDMFB_00999 4.8e-103 estA E Lysophospholipase L1 and related esterases
MEAGDMFB_01000 8.7e-156 rssA S Phospholipase, patatin family
MEAGDMFB_01001 4.3e-173 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MEAGDMFB_01002 2.4e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MEAGDMFB_01003 3.5e-211 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEAGDMFB_01004 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEAGDMFB_01005 4.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEAGDMFB_01006 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MEAGDMFB_01007 1e-224 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01008 1.8e-205 hpk9 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01009 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MEAGDMFB_01010 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEAGDMFB_01011 8.1e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEAGDMFB_01012 0.0 lpdA 1.8.1.4 C Dehydrogenase
MEAGDMFB_01013 0.0 3.5.1.28 NU amidase activity
MEAGDMFB_01014 3.9e-108 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MEAGDMFB_01015 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MEAGDMFB_01016 8.4e-146 ycdO P periplasmic lipoprotein involved in iron transport
MEAGDMFB_01017 2e-230 ycdB P peroxidase
MEAGDMFB_01018 9.7e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MEAGDMFB_01019 4.4e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEAGDMFB_01020 1.9e-23 tatA U protein secretion
MEAGDMFB_01021 1.8e-212 msmX P Belongs to the ABC transporter superfamily
MEAGDMFB_01022 3.7e-151 malG P ABC transporter (Permease
MEAGDMFB_01023 1.7e-249 malF P ABC transporter (Permease
MEAGDMFB_01024 4.3e-228 malX G ABC transporter
MEAGDMFB_01025 2.1e-156 malR K Transcriptional regulator
MEAGDMFB_01026 1.5e-299 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MEAGDMFB_01027 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEAGDMFB_01028 6.8e-39
MEAGDMFB_01029 2.3e-184 lplA 6.3.1.20 H Lipoate-protein ligase
MEAGDMFB_01030 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MEAGDMFB_01031 0.0 pepN 3.4.11.2 E aminopeptidase
MEAGDMFB_01032 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
MEAGDMFB_01033 7.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAGDMFB_01034 5.7e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAGDMFB_01035 9.1e-156 pstA P phosphate transport system permease
MEAGDMFB_01036 2.1e-155 pstC P probably responsible for the translocation of the substrate across the membrane
MEAGDMFB_01037 2.6e-155 pstS P phosphate
MEAGDMFB_01038 1.4e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MEAGDMFB_01039 2.1e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MEAGDMFB_01040 4.3e-43 yktA S Belongs to the UPF0223 family
MEAGDMFB_01041 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEAGDMFB_01042 4.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MEAGDMFB_01043 1.3e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEAGDMFB_01044 4.2e-237 XK27_04775 S hemerythrin HHE cation binding domain
MEAGDMFB_01045 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
MEAGDMFB_01046 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MEAGDMFB_01047 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEAGDMFB_01048 6.2e-137 S haloacid dehalogenase-like hydrolase
MEAGDMFB_01049 1.9e-239 metY 2.5.1.49 E o-acetylhomoserine
MEAGDMFB_01050 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MEAGDMFB_01051 4.2e-237 agcS E (Alanine) symporter
MEAGDMFB_01052 5.8e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEAGDMFB_01053 1e-168 bglC K Transcriptional regulator
MEAGDMFB_01054 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MEAGDMFB_01055 3.5e-80 yecS P ABC transporter (Permease
MEAGDMFB_01056 1.8e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
MEAGDMFB_01057 1.7e-239 nylA 3.5.1.4 J Belongs to the amidase family
MEAGDMFB_01058 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEAGDMFB_01059 4.2e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEAGDMFB_01060 2.2e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEAGDMFB_01061 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MEAGDMFB_01062 4e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MEAGDMFB_01063 6.5e-137 S TraX protein
MEAGDMFB_01064 1.8e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MEAGDMFB_01065 2.3e-271 S Psort location CytoplasmicMembrane, score
MEAGDMFB_01066 5.8e-88 V ABC transporter, ATP-binding protein
MEAGDMFB_01067 1.9e-47
MEAGDMFB_01068 2e-231 dinF V Mate efflux family protein
MEAGDMFB_01069 4.3e-175 yclQ P ABC-type enterochelin transport system, periplasmic component
MEAGDMFB_01070 1.4e-48 S von Willebrand factor (vWF) type A domain
MEAGDMFB_01071 0.0 V Type III restriction enzyme, res subunit
MEAGDMFB_01072 3.2e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MEAGDMFB_01073 3.1e-136 2.4.2.3 F Phosphorylase superfamily
MEAGDMFB_01074 0.0 copA 3.6.3.54 P P-type ATPase
MEAGDMFB_01075 4.8e-66 silP 1.9.3.1, 3.6.3.54 S cog cog4633
MEAGDMFB_01076 6.2e-64 copY K Copper transport repressor, CopY TcrY family
MEAGDMFB_01077 1.3e-185 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MEAGDMFB_01078 5.2e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MEAGDMFB_01079 4.5e-142 czcD P cation diffusion facilitator family transporter
MEAGDMFB_01080 1.1e-98 K Transcriptional regulator, TetR family
MEAGDMFB_01081 7.2e-59 S Protein of unknown function with HXXEE motif
MEAGDMFB_01082 8.4e-38
MEAGDMFB_01083 1.5e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAGDMFB_01084 8.9e-153 I Alpha/beta hydrolase family
MEAGDMFB_01085 1.1e-178 1.1.1.1 C nadph quinone reductase
MEAGDMFB_01086 3.3e-66 K Transcriptional regulator
MEAGDMFB_01087 1.7e-53 pnuC H nicotinamide mononucleotide transporter
MEAGDMFB_01088 1.8e-150 cbiO2 P ABC transporter, ATP-binding protein
MEAGDMFB_01089 1e-156 P ATPase activity
MEAGDMFB_01090 6.3e-132 cbiQ P cobalt transport
MEAGDMFB_01091 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
MEAGDMFB_01092 1.4e-139 S Phenazine biosynthesis protein
MEAGDMFB_01093 1.2e-264 proWX P ABC transporter
MEAGDMFB_01094 5.6e-127 proV E abc transporter atp-binding protein
MEAGDMFB_01095 1.5e-151 C alcohol dehydrogenase
MEAGDMFB_01096 1.1e-64 mgrA K Transcriptional regulator, MarR family
MEAGDMFB_01097 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MEAGDMFB_01098 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MEAGDMFB_01101 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEAGDMFB_01103 2.4e-136 IQ Acetoin reductase
MEAGDMFB_01104 3.7e-45 pspE P Rhodanese-like protein
MEAGDMFB_01105 1.2e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MEAGDMFB_01106 1e-223 XK27_05470 E Methionine synthase
MEAGDMFB_01107 8.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEAGDMFB_01108 1.8e-227 T PhoQ Sensor
MEAGDMFB_01109 3.5e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEAGDMFB_01110 3.2e-147 S TraX protein
MEAGDMFB_01111 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEAGDMFB_01112 5.6e-155 dprA LU DNA protecting protein DprA
MEAGDMFB_01113 5.5e-164 GK ROK family
MEAGDMFB_01114 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAGDMFB_01115 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEAGDMFB_01116 1.2e-126 K DNA-binding helix-turn-helix protein
MEAGDMFB_01117 1.9e-89 niaR S small molecule binding protein (contains 3H domain)
MEAGDMFB_01118 2.7e-86
MEAGDMFB_01119 5e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEAGDMFB_01120 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEAGDMFB_01121 7.7e-126 gntR1 K transcriptional
MEAGDMFB_01122 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEAGDMFB_01123 3.3e-98 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEAGDMFB_01124 2.3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
MEAGDMFB_01125 1e-44
MEAGDMFB_01126 5.8e-51
MEAGDMFB_01127 3.3e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEAGDMFB_01128 2.3e-156 aatB ET ABC transporter substrate-binding protein
MEAGDMFB_01129 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_01130 1.4e-105 artQ P ABC transporter (Permease
MEAGDMFB_01131 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
MEAGDMFB_01132 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEAGDMFB_01133 8.4e-165 cpsY K Transcriptional regulator
MEAGDMFB_01134 1.3e-123 mur1 3.4.17.14, 3.5.1.28 NU muramidase
MEAGDMFB_01135 2.1e-161 yeiH S Membrane
MEAGDMFB_01137 2.6e-09
MEAGDMFB_01138 5.4e-281 adcA P Belongs to the bacterial solute-binding protein 9 family
MEAGDMFB_01139 1.2e-141 XK27_10720 D peptidase activity
MEAGDMFB_01140 1.8e-275 pepD E Dipeptidase
MEAGDMFB_01141 4.8e-160 whiA K May be required for sporulation
MEAGDMFB_01142 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MEAGDMFB_01143 8.5e-162 rapZ S Displays ATPase and GTPase activities
MEAGDMFB_01144 2.6e-135 yejC S cyclic nucleotide-binding protein
MEAGDMFB_01145 6.2e-205 D nuclear chromosome segregation
MEAGDMFB_01146 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MEAGDMFB_01147 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MEAGDMFB_01148 1.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MEAGDMFB_01149 1.7e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MEAGDMFB_01150 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MEAGDMFB_01151 5.3e-18
MEAGDMFB_01152 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MEAGDMFB_01153 9.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MEAGDMFB_01154 1.1e-81 ypmB S Protein conserved in bacteria
MEAGDMFB_01155 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MEAGDMFB_01156 7.3e-115 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MEAGDMFB_01157 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MEAGDMFB_01158 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
MEAGDMFB_01159 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MEAGDMFB_01160 3.2e-187 tcsA S membrane
MEAGDMFB_01161 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MEAGDMFB_01162 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEAGDMFB_01163 1.1e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MEAGDMFB_01164 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
MEAGDMFB_01165 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
MEAGDMFB_01166 1e-29 rpsT J Binds directly to 16S ribosomal RNA
MEAGDMFB_01167 3.9e-241 T PhoQ Sensor
MEAGDMFB_01168 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEAGDMFB_01169 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MEAGDMFB_01170 1.7e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MEAGDMFB_01171 8.2e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEAGDMFB_01172 2.7e-92 panT S ECF transporter, substrate-specific component
MEAGDMFB_01173 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MEAGDMFB_01174 5.3e-164 metF 1.5.1.20 E reductase
MEAGDMFB_01175 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEAGDMFB_01177 2.4e-311 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MEAGDMFB_01178 0.0 3.6.3.8 P cation transport ATPase
MEAGDMFB_01179 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEAGDMFB_01180 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAGDMFB_01181 5.6e-236 dltB M Membrane protein involved in D-alanine export
MEAGDMFB_01182 7.1e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAGDMFB_01183 0.0 XK27_10035 V abc transporter atp-binding protein
MEAGDMFB_01184 1.5e-290 yfiB1 V abc transporter atp-binding protein
MEAGDMFB_01185 1.4e-99 pvaA M lytic transglycosylase activity
MEAGDMFB_01186 2.1e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MEAGDMFB_01187 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEAGDMFB_01188 4.5e-106 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEAGDMFB_01189 3.7e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEAGDMFB_01190 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEAGDMFB_01191 2.6e-109 tdk 2.7.1.21 F thymidine kinase
MEAGDMFB_01192 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MEAGDMFB_01193 1.1e-152 gst O Glutathione S-transferase
MEAGDMFB_01194 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MEAGDMFB_01195 3.5e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEAGDMFB_01196 4.4e-45 rpmE2 J 50S ribosomal protein L31
MEAGDMFB_01197 3.9e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
MEAGDMFB_01198 2.2e-163 ypuA S secreted protein
MEAGDMFB_01199 5.9e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
MEAGDMFB_01200 1.8e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MEAGDMFB_01201 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAGDMFB_01202 5.9e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEAGDMFB_01203 7.8e-255 noxE P NADH oxidase
MEAGDMFB_01204 2.5e-294 yfmM S abc transporter atp-binding protein
MEAGDMFB_01205 5e-77 XK27_01265 S ECF-type riboflavin transporter, S component
MEAGDMFB_01206 1.1e-153 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MEAGDMFB_01207 2.2e-85 S ECF-type riboflavin transporter, S component
MEAGDMFB_01209 5.7e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEAGDMFB_01210 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MEAGDMFB_01212 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAGDMFB_01213 5.4e-35 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEAGDMFB_01214 2.6e-48 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEAGDMFB_01215 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEAGDMFB_01216 3.8e-22 WQ51_00220 K Helix-turn-helix domain
MEAGDMFB_01217 9.1e-90 S Protein of unknown function (DUF3278)
MEAGDMFB_01218 0.0 smc D Required for chromosome condensation and partitioning
MEAGDMFB_01219 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEAGDMFB_01220 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEAGDMFB_01221 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEAGDMFB_01222 4.7e-117 alkD L DNA alkylation repair enzyme
MEAGDMFB_01223 2.6e-291 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAGDMFB_01224 6.3e-93 pat 2.3.1.183 M acetyltransferase
MEAGDMFB_01225 2.5e-272 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAGDMFB_01226 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MEAGDMFB_01227 2.4e-49 L COG1943 Transposase and inactivated derivatives
MEAGDMFB_01228 1.2e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MEAGDMFB_01229 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEAGDMFB_01230 4.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MEAGDMFB_01231 1.5e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MEAGDMFB_01232 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
MEAGDMFB_01233 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
MEAGDMFB_01234 1.9e-133 L Integrase
MEAGDMFB_01235 2e-202 S Protein of unknown function DUF262
MEAGDMFB_01236 2.1e-151 S Protein of unknown function DUF262
MEAGDMFB_01237 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MEAGDMFB_01238 1.4e-79 3.4.21.89 S RDD family
MEAGDMFB_01239 1.3e-152 K sequence-specific DNA binding
MEAGDMFB_01240 4e-153 V ABC transporter, ATP-binding protein
MEAGDMFB_01241 7.2e-103 S ABC-2 family transporter protein
MEAGDMFB_01242 8.7e-162 K sequence-specific DNA binding
MEAGDMFB_01243 6.6e-50 ywrO S general stress protein
MEAGDMFB_01244 1.7e-221 L transposase IS116 IS110 IS902 family
MEAGDMFB_01245 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
MEAGDMFB_01246 5.2e-78 K Acetyltransferase (GNAT) domain
MEAGDMFB_01247 5.6e-141 S ABC-2 family transporter protein
MEAGDMFB_01248 1.5e-141 S ABC-2 family transporter protein
MEAGDMFB_01249 1.4e-184 S abc transporter atp-binding protein
MEAGDMFB_01252 2.8e-84 yfjR K regulation of single-species biofilm formation
MEAGDMFB_01253 8.8e-125 S Protein of unknown function DUF262
MEAGDMFB_01254 1.8e-204 S Protein of unknown function DUF262
MEAGDMFB_01255 5.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEAGDMFB_01256 4.5e-189 desK 2.7.13.3 T Histidine kinase
MEAGDMFB_01257 1.5e-132 yvfS V ABC-2 type transporter
MEAGDMFB_01258 6.7e-159 XK27_09825 V 'abc transporter, ATP-binding protein
MEAGDMFB_01262 1.8e-195 anK3 G response to abiotic stimulus
MEAGDMFB_01263 0.0 hscC O Belongs to the heat shock protein 70 family
MEAGDMFB_01264 2.5e-153 yocS S Transporter
MEAGDMFB_01265 3.7e-69 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
MEAGDMFB_01266 7.6e-124 yvfS V Transporter
MEAGDMFB_01267 2.5e-158 XK27_09825 V abc transporter atp-binding protein
MEAGDMFB_01268 6.3e-16 liaI KT membrane
MEAGDMFB_01269 5.8e-30 liaI KT membrane
MEAGDMFB_01270 6.1e-93 XK27_05000 S metal cluster binding
MEAGDMFB_01271 0.0 V ABC transporter (permease)
MEAGDMFB_01272 1.6e-132 macB2 V ABC transporter, ATP-binding protein
MEAGDMFB_01273 4.9e-163 T Histidine kinase
MEAGDMFB_01274 2.7e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEAGDMFB_01275 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEAGDMFB_01276 4.7e-222 pbuX F xanthine permease
MEAGDMFB_01277 1.4e-58 pdxH S pyridoxamine 5'-phosphate oxidase
MEAGDMFB_01278 1.5e-242 norM V Multidrug efflux pump
MEAGDMFB_01280 1.2e-177 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEAGDMFB_01281 3.5e-228 brnQ E Component of the transport system for branched-chain amino acids
MEAGDMFB_01282 7.8e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEAGDMFB_01283 2e-58 S Protein of unknown function (DUF3290)
MEAGDMFB_01284 6e-101 S Protein of unknown function (DUF421)
MEAGDMFB_01285 5.9e-15 csbD K CsbD-like
MEAGDMFB_01286 7.3e-76 S Carbohydrate-binding domain-containing protein Cthe_2159
MEAGDMFB_01287 9.7e-37 XK27_01300 S ASCH
MEAGDMFB_01288 2.2e-212 yfnA E amino acid
MEAGDMFB_01289 0.0 S dextransucrase activity
MEAGDMFB_01290 6.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MEAGDMFB_01291 1.5e-42 S Sugar efflux transporter for intercellular exchange
MEAGDMFB_01292 3e-204 P FtsX-like permease family
MEAGDMFB_01293 6e-123 V abc transporter atp-binding protein
MEAGDMFB_01294 1.1e-96 K WHG domain
MEAGDMFB_01295 7.5e-169 ydhF S Aldo keto reductase
MEAGDMFB_01297 2.8e-35
MEAGDMFB_01298 8.7e-110 XK27_02070 S nitroreductase
MEAGDMFB_01299 2.2e-149 1.13.11.2 S glyoxalase
MEAGDMFB_01300 1.5e-74 ywnA K Transcriptional regulator
MEAGDMFB_01301 7e-153 E Alpha/beta hydrolase of unknown function (DUF915)
MEAGDMFB_01302 4.9e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEAGDMFB_01303 1.1e-167 bcrA V abc transporter atp-binding protein
MEAGDMFB_01304 1.3e-123 S ABC-2 family transporter protein
MEAGDMFB_01305 2.7e-144 T PhoQ Sensor
MEAGDMFB_01306 6.4e-125 T Xre family transcriptional regulator
MEAGDMFB_01307 6e-109 drgA C nitroreductase
MEAGDMFB_01308 1.6e-104 yoaK S Protein of unknown function (DUF1275)
MEAGDMFB_01309 1.1e-40 DJ nuclease activity
MEAGDMFB_01310 1.9e-30 XK27_10490
MEAGDMFB_01311 2.1e-157 yvgN C reductase
MEAGDMFB_01312 4.9e-210 S Tetratricopeptide repeat
MEAGDMFB_01313 0.0 lacL 3.2.1.23 G -beta-galactosidase
MEAGDMFB_01314 0.0 lacS G transporter
MEAGDMFB_01315 1.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MEAGDMFB_01316 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEAGDMFB_01317 7.8e-285 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MEAGDMFB_01318 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEAGDMFB_01319 2.6e-151 galR K Transcriptional regulator
MEAGDMFB_01320 2.9e-309 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
MEAGDMFB_01321 1.3e-227 vncS 2.7.13.3 T Histidine kinase
MEAGDMFB_01322 4.4e-115 K Response regulator receiver domain protein
MEAGDMFB_01323 2.6e-234 vex3 V Efflux ABC transporter, permease protein
MEAGDMFB_01324 2.3e-105 vex2 V abc transporter atp-binding protein
MEAGDMFB_01325 2.4e-210 vex1 V Efflux ABC transporter, permease protein
MEAGDMFB_01326 5e-284 XK27_07020 S Belongs to the UPF0371 family
MEAGDMFB_01328 2.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
MEAGDMFB_01329 4.2e-178 XK27_10475 S oxidoreductase
MEAGDMFB_01330 2.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
MEAGDMFB_01331 1.1e-93 dhaL 2.7.1.121 S Dihydroxyacetone kinase
MEAGDMFB_01332 8.5e-179 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
MEAGDMFB_01333 2.2e-224 thrE K Psort location CytoplasmicMembrane, score
MEAGDMFB_01334 0.0 M Putative cell wall binding repeat
MEAGDMFB_01335 4.1e-34 S Immunity protein 41
MEAGDMFB_01336 0.0 pepO 3.4.24.71 O Peptidase family M13
MEAGDMFB_01337 9e-08 S Enterocin A Immunity
MEAGDMFB_01338 6.4e-193 mccF V LD-carboxypeptidase
MEAGDMFB_01339 4.6e-15 S integral membrane protein
MEAGDMFB_01340 5.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
MEAGDMFB_01341 6.9e-117 yhfC S Putative membrane peptidase family (DUF2324)
MEAGDMFB_01342 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_01343 2.1e-253 S dextransucrase activity
MEAGDMFB_01344 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_01345 9.1e-36 M Putative cell wall binding repeat
MEAGDMFB_01346 1.2e-22 S dextransucrase activity
MEAGDMFB_01347 8.9e-238 M Putative cell wall binding repeat
MEAGDMFB_01348 2.2e-236 S dextransucrase activity
MEAGDMFB_01349 3.1e-92 S dextransucrase activity
MEAGDMFB_01350 0.0 S dextransucrase activity
MEAGDMFB_01351 5.5e-63
MEAGDMFB_01352 4.6e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MEAGDMFB_01353 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MEAGDMFB_01354 6e-293 S dextransucrase activity
MEAGDMFB_01355 3e-174 S dextransucrase activity
MEAGDMFB_01356 0.0 S dextransucrase activity
MEAGDMFB_01357 0.0 M Putative cell wall binding repeat
MEAGDMFB_01358 1.5e-227 S dextransucrase activity
MEAGDMFB_01360 4.2e-117 XK27_00785 S CAAX protease self-immunity
MEAGDMFB_01361 1.5e-234 EGP Major facilitator Superfamily
MEAGDMFB_01362 6.5e-64 rmaI K Transcriptional regulator, MarR family
MEAGDMFB_01363 3.5e-92 maa 2.3.1.79 GK Maltose O-acetyltransferase
MEAGDMFB_01364 8.9e-65 2.7.13.3 T Histidine kinase
MEAGDMFB_01365 1.1e-73 K Transcriptional regulatory protein, C terminal
MEAGDMFB_01367 1.6e-13
MEAGDMFB_01368 4.3e-87 V abc transporter atp-binding protein
MEAGDMFB_01369 0.0 3.5.1.28 M domain protein
MEAGDMFB_01370 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MEAGDMFB_01371 2.7e-23
MEAGDMFB_01377 1.9e-276 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
MEAGDMFB_01378 1.5e-183 nss M transferase activity, transferring glycosyl groups
MEAGDMFB_01379 3.6e-16 S Accessory secretory protein Sec, Asp5
MEAGDMFB_01380 2.6e-17 S Accessory secretory protein Sec Asp4
MEAGDMFB_01381 2.8e-241 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MEAGDMFB_01382 1.5e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MEAGDMFB_01383 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEAGDMFB_01384 1.7e-78 asp3 S Accessory Sec system protein Asp3
MEAGDMFB_01385 8.3e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
MEAGDMFB_01386 2.9e-290 asp1 S Accessory Sec system protein Asp1
MEAGDMFB_01387 6.1e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MEAGDMFB_01388 0.0 M family 8
MEAGDMFB_01389 0.0 sbcC L ATPase involved in DNA repair
MEAGDMFB_01390 9e-215 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEAGDMFB_01391 0.0 GM domain, Protein
MEAGDMFB_01392 0.0 zmpB M signal peptide protein, YSIRK family
MEAGDMFB_01393 1.2e-22 L Transposase (IS116 IS110 IS902 family)
MEAGDMFB_01394 6.2e-32 L PFAM transposase IS116 IS110 IS902 family
MEAGDMFB_01395 2e-192 L Transposase
MEAGDMFB_01396 1e-101 D Domain of Unknown Function (DUF1542)
MEAGDMFB_01397 0.0 M domain protein
MEAGDMFB_01399 8.9e-12
MEAGDMFB_01400 5.9e-187 XK27_10075 S abc transporter atp-binding protein
MEAGDMFB_01401 0.0 V abc transporter atp-binding protein
MEAGDMFB_01402 1.4e-296 V abc transporter atp-binding protein
MEAGDMFB_01403 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MEAGDMFB_01405 1.6e-285 S Protein of unknown function (DUF3114)
MEAGDMFB_01406 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
MEAGDMFB_01407 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEAGDMFB_01408 1.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEAGDMFB_01409 9.8e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
MEAGDMFB_01410 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEAGDMFB_01411 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEAGDMFB_01412 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MEAGDMFB_01413 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEAGDMFB_01414 2.8e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MEAGDMFB_01415 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEAGDMFB_01416 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEAGDMFB_01419 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEAGDMFB_01420 1.3e-169 vraS 2.7.13.3 T Histidine kinase
MEAGDMFB_01421 1.6e-115 yvqF S Membrane
MEAGDMFB_01422 4.1e-104 kcsA P Ion transport protein
MEAGDMFB_01423 5.4e-291 prkC 2.7.11.1 KLT serine threonine protein kinase
MEAGDMFB_01424 2.9e-134 stp 3.1.3.16 T phosphatase
MEAGDMFB_01425 7.8e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEAGDMFB_01426 5.2e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEAGDMFB_01427 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEAGDMFB_01428 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MEAGDMFB_01429 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MEAGDMFB_01430 3.5e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEAGDMFB_01431 3.3e-144 XK27_02985 S overlaps another CDS with the same product name
MEAGDMFB_01432 4.5e-146 supH S overlaps another CDS with the same product name
MEAGDMFB_01433 1.9e-62 yvoA_1 K Transcriptional
MEAGDMFB_01434 2.3e-117 skfE V abc transporter atp-binding protein
MEAGDMFB_01435 1.4e-128 V Psort location CytoplasmicMembrane, score
MEAGDMFB_01436 1.4e-170 oppF P Belongs to the ABC transporter superfamily
MEAGDMFB_01437 3.9e-201 oppD P Belongs to the ABC transporter superfamily
MEAGDMFB_01438 3.8e-165 amiD P ABC transporter (Permease
MEAGDMFB_01439 2.1e-274 amiC P ABC transporter (Permease
MEAGDMFB_01440 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
MEAGDMFB_01441 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MEAGDMFB_01442 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MEAGDMFB_01443 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEAGDMFB_01444 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEAGDMFB_01445 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MEAGDMFB_01446 6e-100 yjbK S Adenylate cyclase
MEAGDMFB_01447 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAGDMFB_01448 3.3e-203 iscS 2.8.1.7 E Cysteine desulfurase
MEAGDMFB_01449 8.2e-60 XK27_04120 S Putative amino acid metabolism
MEAGDMFB_01450 5.6e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEAGDMFB_01451 4.4e-129 puuD T peptidase C26
MEAGDMFB_01452 1.5e-118 radC E Belongs to the UPF0758 family
MEAGDMFB_01453 0.0 rgpF M Rhamnan synthesis protein F
MEAGDMFB_01454 1.2e-183 rgpEc GT2 M Glycosyl transferase family 2
MEAGDMFB_01455 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEAGDMFB_01456 1.2e-141 rgpC GM Transport permease protein
MEAGDMFB_01457 1.1e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
MEAGDMFB_01458 6.8e-212 rgpA GT4 M Domain of unknown function (DUF1972)
MEAGDMFB_01459 3.5e-180 tagF 2.7.8.12 M Glycosyl transferase, family 2
MEAGDMFB_01460 1.1e-215 amrA S polysaccharide biosynthetic process
MEAGDMFB_01461 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
MEAGDMFB_01462 3.2e-124 ycbB S Glycosyl transferase family 2
MEAGDMFB_01463 1.3e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEAGDMFB_01464 2e-169 yfdH 2.4.2.53 GT2 M group 2 family protein
MEAGDMFB_01465 3.5e-218 M Psort location CytoplasmicMembrane, score
MEAGDMFB_01466 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MEAGDMFB_01467 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEAGDMFB_01468 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEAGDMFB_01469 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEAGDMFB_01470 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MEAGDMFB_01471 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
MEAGDMFB_01472 8.9e-209 arcT 2.6.1.1 E Aminotransferase
MEAGDMFB_01473 2.2e-137 ET Belongs to the bacterial solute-binding protein 3 family
MEAGDMFB_01474 1.9e-139 ET ABC transporter
MEAGDMFB_01475 1.1e-80 mutT 3.6.1.55 F Nudix family
MEAGDMFB_01476 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEAGDMFB_01478 2.1e-163 S CAAX amino terminal protease family protein
MEAGDMFB_01479 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MEAGDMFB_01480 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_01481 1.7e-17 XK27_00735
MEAGDMFB_01482 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEAGDMFB_01484 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEAGDMFB_01485 4.4e-10 O ADP-ribosylglycohydrolase
MEAGDMFB_01486 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
MEAGDMFB_01487 6e-61 ycaO O OsmC-like protein
MEAGDMFB_01489 7e-148 EG Permeases of the drug metabolite transporter (DMT) superfamily
MEAGDMFB_01491 2.6e-112 serB 3.1.3.3 E phosphoserine phosphatase
MEAGDMFB_01492 8.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEAGDMFB_01493 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAGDMFB_01494 1.8e-93 3.1.3.18 S IA, variant 1
MEAGDMFB_01495 1.1e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MEAGDMFB_01496 5.9e-56 lrgA S Effector of murein hydrolase LrgA
MEAGDMFB_01498 3.9e-57 arsC 1.20.4.1 P Belongs to the ArsC family
MEAGDMFB_01499 1.3e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MEAGDMFB_01500 2.9e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAGDMFB_01501 1.1e-103 wecD M Acetyltransferase (GNAT) domain
MEAGDMFB_01502 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEAGDMFB_01503 9.8e-158 GK ROK family
MEAGDMFB_01504 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
MEAGDMFB_01505 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
MEAGDMFB_01506 1.8e-203 potD P spermidine putrescine ABC transporter
MEAGDMFB_01507 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
MEAGDMFB_01508 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
MEAGDMFB_01509 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEAGDMFB_01510 1.8e-167 murB 1.3.1.98 M cell wall formation
MEAGDMFB_01511 1.4e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MEAGDMFB_01512 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEAGDMFB_01513 2.2e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MEAGDMFB_01514 3.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MEAGDMFB_01515 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
MEAGDMFB_01516 0.0 ydaO E amino acid
MEAGDMFB_01517 2.3e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEAGDMFB_01518 1.5e-36 ylqC L Belongs to the UPF0109 family
MEAGDMFB_01519 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEAGDMFB_01521 8.1e-201 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01522 2.6e-124 agrA KT phosphorelay signal transduction system
MEAGDMFB_01523 4.3e-167 O protein import
MEAGDMFB_01524 9.6e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MEAGDMFB_01525 1.7e-17 yjdB S Domain of unknown function (DUF4767)
MEAGDMFB_01526 8.7e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEAGDMFB_01528 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
MEAGDMFB_01529 5.8e-72 S QueT transporter
MEAGDMFB_01531 3.2e-170 yfjR K regulation of single-species biofilm formation
MEAGDMFB_01533 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEAGDMFB_01534 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEAGDMFB_01535 2.8e-85 ccl S cog cog4708
MEAGDMFB_01536 8.4e-160 rbn E Belongs to the UPF0761 family
MEAGDMFB_01537 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MEAGDMFB_01538 6.6e-232 ytoI K transcriptional regulator containing CBS domains
MEAGDMFB_01539 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MEAGDMFB_01540 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEAGDMFB_01541 0.0 comEC S Competence protein ComEC
MEAGDMFB_01542 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MEAGDMFB_01543 2.9e-142 plsC 2.3.1.51 I Acyltransferase
MEAGDMFB_01544 8.1e-147 nodB3 G Polysaccharide deacetylase
MEAGDMFB_01545 3.5e-140 yabB 2.1.1.223 L Methyltransferase
MEAGDMFB_01546 6.6e-41 yazA L endonuclease containing a URI domain
MEAGDMFB_01547 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEAGDMFB_01548 1.6e-152 corA P CorA-like protein
MEAGDMFB_01549 3.3e-62 yjqA S Bacterial PH domain
MEAGDMFB_01550 1.7e-99 thiT S Thiamine transporter
MEAGDMFB_01551 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEAGDMFB_01552 2e-115 ywaF S Integral membrane protein (intg_mem_TP0381)
MEAGDMFB_01553 1.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEAGDMFB_01557 3.3e-155 cjaA ET ABC transporter substrate-binding protein
MEAGDMFB_01558 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_01559 4.6e-107 P ABC transporter (Permease
MEAGDMFB_01560 3e-114 papP P ABC transporter (Permease
MEAGDMFB_01561 3.5e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEAGDMFB_01562 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MEAGDMFB_01563 0.0 copA 3.6.3.54 P P-type ATPase
MEAGDMFB_01564 1.8e-72 copY K negative regulation of transcription, DNA-templated
MEAGDMFB_01565 7.8e-163 EGP Major facilitator Superfamily
MEAGDMFB_01567 1.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEAGDMFB_01568 3.2e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEAGDMFB_01569 3.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MEAGDMFB_01570 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MEAGDMFB_01571 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEAGDMFB_01572 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MEAGDMFB_01573 1.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEAGDMFB_01574 2.2e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
MEAGDMFB_01575 1.2e-59
MEAGDMFB_01576 0.0 ctpE P E1-E2 ATPase
MEAGDMFB_01577 2.6e-46
MEAGDMFB_01578 7.8e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEAGDMFB_01580 1.9e-124 V abc transporter atp-binding protein
MEAGDMFB_01581 0.0 V ABC transporter (Permease
MEAGDMFB_01582 8.9e-125 K transcriptional regulator, MerR family
MEAGDMFB_01583 3.2e-104 dnaQ 2.7.7.7 L DNA polymerase III
MEAGDMFB_01584 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
MEAGDMFB_01585 3.7e-63 XK27_02560 S cog cog2151
MEAGDMFB_01586 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MEAGDMFB_01587 1.2e-213 ytfP S Flavoprotein
MEAGDMFB_01588 4.7e-72 L COG1943 Transposase and inactivated derivatives
MEAGDMFB_01590 1.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEAGDMFB_01591 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
MEAGDMFB_01592 2.5e-173 ecsB U Bacterial ABC transporter protein EcsB
MEAGDMFB_01593 1.9e-130 ecsA V abc transporter atp-binding protein
MEAGDMFB_01594 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MEAGDMFB_01596 3.8e-33
MEAGDMFB_01597 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MEAGDMFB_01599 1.3e-196 ylbM S Belongs to the UPF0348 family
MEAGDMFB_01600 1.3e-139 yqeM Q Methyltransferase domain protein
MEAGDMFB_01601 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEAGDMFB_01602 1.3e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MEAGDMFB_01603 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEAGDMFB_01604 7.7e-49 yhbY J RNA-binding protein
MEAGDMFB_01605 8.6e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MEAGDMFB_01606 2.3e-98 yqeG S hydrolase of the HAD superfamily
MEAGDMFB_01607 1.5e-34 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEAGDMFB_01608 1.9e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MEAGDMFB_01609 4.8e-61
MEAGDMFB_01610 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEAGDMFB_01611 1.5e-57
MEAGDMFB_01612 8.5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
MEAGDMFB_01613 1e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
MEAGDMFB_01614 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
MEAGDMFB_01615 7.9e-30 S PQ loop repeat
MEAGDMFB_01616 1.6e-36 S Sulfite exporter TauE/SafE
MEAGDMFB_01617 2.7e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAGDMFB_01619 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAGDMFB_01620 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEAGDMFB_01621 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAGDMFB_01622 8.1e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MEAGDMFB_01623 3.8e-187 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MEAGDMFB_01624 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
MEAGDMFB_01625 1e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MEAGDMFB_01626 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAGDMFB_01627 5.8e-100 pncA Q isochorismatase
MEAGDMFB_01628 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MEAGDMFB_01629 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MEAGDMFB_01630 9e-75 XK27_03180 T universal stress protein
MEAGDMFB_01632 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEAGDMFB_01633 2.5e-10 MU outer membrane autotransporter barrel domain protein
MEAGDMFB_01634 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MEAGDMFB_01635 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MEAGDMFB_01636 0.0 yjcE P NhaP-type Na H and K H antiporters
MEAGDMFB_01638 3.6e-94 ytqB 2.1.1.176 J (SAM)-dependent
MEAGDMFB_01639 2.3e-181 yhcC S radical SAM protein
MEAGDMFB_01640 3.2e-187 ylbL T Belongs to the peptidase S16 family
MEAGDMFB_01641 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEAGDMFB_01642 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
MEAGDMFB_01643 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEAGDMFB_01644 5e-10 S Protein of unknown function (DUF4059)
MEAGDMFB_01645 2.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
MEAGDMFB_01646 6.8e-162 yxeN P ABC transporter (Permease
MEAGDMFB_01647 7.2e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MEAGDMFB_01648 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MEAGDMFB_01649 2.1e-35
MEAGDMFB_01650 1.9e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEAGDMFB_01651 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MEAGDMFB_01652 2.1e-143 cah 4.2.1.1 P carbonic anhydrase
MEAGDMFB_01653 1.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEAGDMFB_01656 3.8e-168 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MEAGDMFB_01657 4.7e-137 cppA E CppA N-terminal
MEAGDMFB_01658 1.2e-94 V CAAX protease self-immunity
MEAGDMFB_01659 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MEAGDMFB_01660 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEAGDMFB_01661 1.8e-07
MEAGDMFB_01664 5.4e-44 spiA K sequence-specific DNA binding
MEAGDMFB_01670 1.5e-25 S Bacteriocin class II with double-glycine leader peptide
MEAGDMFB_01671 0.0 mdlB V abc transporter atp-binding protein
MEAGDMFB_01672 0.0 mdlA V abc transporter atp-binding protein
MEAGDMFB_01675 5.5e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
MEAGDMFB_01676 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEAGDMFB_01677 1.8e-61 yutD J protein conserved in bacteria
MEAGDMFB_01678 6.9e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MEAGDMFB_01680 8.4e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEAGDMFB_01681 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEAGDMFB_01682 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MEAGDMFB_01683 4e-45 ftsL D cell division protein FtsL
MEAGDMFB_01684 6.7e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEAGDMFB_01685 1.8e-94
MEAGDMFB_01688 2.2e-45 yhaI J Protein of unknown function (DUF805)
MEAGDMFB_01689 1.7e-56 yhaI J Protein of unknown function (DUF805)
MEAGDMFB_01690 2.9e-86 L Endonuclease
MEAGDMFB_01691 1.1e-15 L Transposase and inactivated derivatives
MEAGDMFB_01692 1.8e-12 yhaI J Protein of unknown function (DUF805)
MEAGDMFB_01693 2.4e-52 yhaI J Membrane
MEAGDMFB_01694 1e-221 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEAGDMFB_01695 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEAGDMFB_01696 4.3e-273 XK27_00765
MEAGDMFB_01697 2.6e-132 ecsA_2 V abc transporter atp-binding protein
MEAGDMFB_01698 2.2e-125 S Protein of unknown function (DUF554)
MEAGDMFB_01699 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MEAGDMFB_01700 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MEAGDMFB_01701 2.1e-244 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01702 2.5e-234 dcuS 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01703 6.8e-14
MEAGDMFB_01706 5.8e-146 V Psort location CytoplasmicMembrane, score
MEAGDMFB_01708 1.7e-298 O MreB/Mbl protein
MEAGDMFB_01709 4.8e-120 liaI S membrane
MEAGDMFB_01710 2e-74 XK27_02470 K LytTr DNA-binding domain protein
MEAGDMFB_01711 0.0 KT response to antibiotic
MEAGDMFB_01712 6.8e-98 yebC M Membrane
MEAGDMFB_01713 1.4e-259 XK27_03190 S hydrolases of the HAD superfamily
MEAGDMFB_01714 7.1e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MEAGDMFB_01716 2.4e-30 yozG K Transcriptional regulator
MEAGDMFB_01720 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEAGDMFB_01721 5.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEAGDMFB_01722 1.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEAGDMFB_01723 1.6e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEAGDMFB_01724 1.6e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEAGDMFB_01725 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEAGDMFB_01727 2.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEAGDMFB_01728 3.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MEAGDMFB_01729 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_01730 1.4e-283 scrB 3.2.1.26 GH32 G invertase
MEAGDMFB_01731 3.9e-176 scrR K Transcriptional regulator
MEAGDMFB_01732 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEAGDMFB_01733 1.7e-61 yqhY S protein conserved in bacteria
MEAGDMFB_01734 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEAGDMFB_01735 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
MEAGDMFB_01736 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MEAGDMFB_01738 3.3e-144 V 'abc transporter, ATP-binding protein
MEAGDMFB_01739 2.8e-32 blpT
MEAGDMFB_01743 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MEAGDMFB_01744 8.4e-168 corA P COG0598 Mg2 and Co2 transporters
MEAGDMFB_01745 3.8e-122 XK27_01040 S Protein of unknown function (DUF1129)
MEAGDMFB_01747 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEAGDMFB_01748 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEAGDMFB_01749 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MEAGDMFB_01750 9.5e-42 XK27_05745
MEAGDMFB_01751 3.3e-222 mutY L A G-specific adenine glycosylase
MEAGDMFB_01753 4.9e-34
MEAGDMFB_01755 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEAGDMFB_01756 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEAGDMFB_01757 6.1e-94 cvpA S toxin biosynthetic process
MEAGDMFB_01758 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEAGDMFB_01759 2.1e-152 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAGDMFB_01760 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MEAGDMFB_01761 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEAGDMFB_01762 1.3e-46 azlD S branched-chain amino acid
MEAGDMFB_01763 1.5e-113 azlC E AzlC protein
MEAGDMFB_01764 4e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEAGDMFB_01765 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MEAGDMFB_01766 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MEAGDMFB_01767 4.3e-33 ykzG S Belongs to the UPF0356 family
MEAGDMFB_01768 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAGDMFB_01769 2.1e-114 pscB M CHAP domain protein
MEAGDMFB_01770 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
MEAGDMFB_01771 2.5e-62 glnR K Transcriptional regulator
MEAGDMFB_01772 3e-87 S Fusaric acid resistance protein-like
MEAGDMFB_01773 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MEAGDMFB_01774 2.3e-117
MEAGDMFB_01775 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
MEAGDMFB_01776 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEAGDMFB_01777 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEAGDMFB_01778 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEAGDMFB_01779 4e-142 purR 2.4.2.7 F operon repressor
MEAGDMFB_01780 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
MEAGDMFB_01781 2.5e-170 rmuC S RmuC domain protein
MEAGDMFB_01782 2.3e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEAGDMFB_01783 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEAGDMFB_01784 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEAGDMFB_01786 2.9e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEAGDMFB_01787 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEAGDMFB_01788 4.7e-143 tatD L Hydrolase, tatd
MEAGDMFB_01789 7.2e-74 yccU S CoA-binding protein
MEAGDMFB_01790 2.4e-50 trxA O Belongs to the thioredoxin family
MEAGDMFB_01791 2.3e-142 S Macro domain protein
MEAGDMFB_01792 1.1e-60 L thioesterase
MEAGDMFB_01793 9.3e-53 bta 1.8.1.8 CO cell redox homeostasis
MEAGDMFB_01796 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEAGDMFB_01797 3.4e-14 rpmH J Ribosomal protein L34
MEAGDMFB_01798 5.9e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
MEAGDMFB_01799 1.2e-103 K Transcriptional regulator
MEAGDMFB_01800 3.7e-172 jag S RNA-binding protein
MEAGDMFB_01801 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAGDMFB_01802 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEAGDMFB_01803 3.5e-263 argH 4.3.2.1 E Argininosuccinate lyase
MEAGDMFB_01804 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEAGDMFB_01805 7.2e-130 fasA KT Response regulator of the LytR AlgR family
MEAGDMFB_01806 2.6e-223 fasC 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01807 7.3e-207 hpk9 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01808 3e-151 hpk9 2.7.13.3 T protein histidine kinase activity
MEAGDMFB_01809 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MEAGDMFB_01810 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEAGDMFB_01811 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MEAGDMFB_01812 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEAGDMFB_01813 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEAGDMFB_01814 4.6e-50 S Protein of unknown function (DUF3397)
MEAGDMFB_01815 5.9e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MEAGDMFB_01816 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
MEAGDMFB_01817 3.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEAGDMFB_01818 6.4e-77 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
MEAGDMFB_01819 1e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MEAGDMFB_01820 5.3e-107 XK27_09620 S FMN reductase (NADPH) activity
MEAGDMFB_01821 7.9e-230 XK27_09615 C reductase
MEAGDMFB_01822 8.2e-140 fnt P Formate nitrite transporter
MEAGDMFB_01823 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
MEAGDMFB_01824 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MEAGDMFB_01825 2.5e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEAGDMFB_01826 3.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MEAGDMFB_01827 1.8e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEAGDMFB_01828 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEAGDMFB_01829 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEAGDMFB_01830 5.6e-138 S HAD hydrolase, family IA, variant
MEAGDMFB_01831 2e-157 rrmA 2.1.1.187 Q methyltransferase
MEAGDMFB_01835 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEAGDMFB_01836 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEAGDMFB_01837 3.7e-117 S CAAX protease self-immunity
MEAGDMFB_01838 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAGDMFB_01839 2.6e-09 S NTF2 fold immunity protein
MEAGDMFB_01840 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEAGDMFB_01841 1e-07 S Domain of unknown function (DUF4651)
MEAGDMFB_01842 1.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MEAGDMFB_01843 2.6e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEAGDMFB_01844 1.1e-100 S CAAX amino terminal protease family protein
MEAGDMFB_01846 8.1e-109 V CAAX protease self-immunity
MEAGDMFB_01847 8.8e-27 lanR K sequence-specific DNA binding
MEAGDMFB_01848 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEAGDMFB_01849 4.7e-174 ytxK 2.1.1.72 L DNA methylase
MEAGDMFB_01850 2e-12 comGF U Putative Competence protein ComGF
MEAGDMFB_01851 2e-71 comGF U Competence protein ComGF
MEAGDMFB_01852 3.1e-15 NU Type II secretory pathway pseudopilin
MEAGDMFB_01853 2.4e-69 cglD NU Competence protein
MEAGDMFB_01854 4.7e-41 comGC U Required for transformation and DNA binding
MEAGDMFB_01855 9.7e-144 cglB U protein transport across the cell outer membrane
MEAGDMFB_01856 3.5e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MEAGDMFB_01857 1e-68 S cog cog4699
MEAGDMFB_01858 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAGDMFB_01859 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAGDMFB_01860 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEAGDMFB_01861 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEAGDMFB_01862 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEAGDMFB_01863 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
MEAGDMFB_01864 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MEAGDMFB_01865 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MEAGDMFB_01866 6e-302 yloV S kinase related to dihydroxyacetone kinase
MEAGDMFB_01867 1.4e-57 asp S cog cog1302
MEAGDMFB_01868 1.2e-225 norN V Mate efflux family protein
MEAGDMFB_01869 2.7e-277 thrC 4.2.3.1 E Threonine synthase
MEAGDMFB_01872 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MEAGDMFB_01873 0.0 pepO 3.4.24.71 O Peptidase family M13
MEAGDMFB_01874 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MEAGDMFB_01875 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_01876 4.3e-124 treR K trehalose operon
MEAGDMFB_01877 4.3e-95 ywlG S Belongs to the UPF0340 family
MEAGDMFB_01881 0.0 V ABC transporter (Permease)
MEAGDMFB_01882 1e-98 V ABC transporter, ATP-binding protein
MEAGDMFB_01883 3.4e-122 cmk 2.7.4.25, 5.3.1.12 F AAA domain
MEAGDMFB_01884 1.4e-114 S Pseudomonas avirulence D protein (AvrD)
MEAGDMFB_01885 3e-78 T regulator
MEAGDMFB_01886 2.3e-158 2.7.13.3 T Histidine kinase
MEAGDMFB_01887 6.5e-30 V Restriction endonuclease
MEAGDMFB_01888 5.2e-23
MEAGDMFB_01889 1e-109 K Peptidase S24-like protein
MEAGDMFB_01890 1e-132 E IrrE N-terminal-like domain
MEAGDMFB_01894 8.3e-49 K Bacteriophage CI repressor helix-turn-helix domain
MEAGDMFB_01895 1.5e-41
MEAGDMFB_01896 1.7e-73
MEAGDMFB_01897 6.4e-275 ydcQ D Ftsk spoiiie family protein
MEAGDMFB_01898 4.4e-225 K Replication initiation factor
MEAGDMFB_01899 4.3e-33
MEAGDMFB_01900 3.9e-88
MEAGDMFB_01901 9.5e-162 S Conjugative transposon protein TcpC
MEAGDMFB_01902 3.2e-33
MEAGDMFB_01903 3.5e-70 S TcpE family
MEAGDMFB_01904 0.0 yddE S AAA-like domain
MEAGDMFB_01905 6e-266
MEAGDMFB_01906 4.4e-30
MEAGDMFB_01907 6.2e-170 isp2 S pathogenesis
MEAGDMFB_01908 4e-16
MEAGDMFB_01909 5e-198 L DNA integration
MEAGDMFB_01910 2e-163 fba 4.1.2.13, 4.1.2.29 G aldolase
MEAGDMFB_01912 2.1e-246 6.3.2.2 H gamma-glutamylcysteine synthetase
MEAGDMFB_01913 4.4e-62 rplQ J ribosomal protein l17
MEAGDMFB_01914 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAGDMFB_01915 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEAGDMFB_01916 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEAGDMFB_01917 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEAGDMFB_01918 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEAGDMFB_01919 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEAGDMFB_01920 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEAGDMFB_01921 5.7e-58 rplO J binds to the 23S rRNA
MEAGDMFB_01922 1.9e-23 rpmD J ribosomal protein l30
MEAGDMFB_01923 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEAGDMFB_01924 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEAGDMFB_01925 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEAGDMFB_01926 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEAGDMFB_01927 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEAGDMFB_01928 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEAGDMFB_01929 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEAGDMFB_01930 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEAGDMFB_01931 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEAGDMFB_01932 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MEAGDMFB_01933 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEAGDMFB_01934 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEAGDMFB_01935 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEAGDMFB_01936 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEAGDMFB_01937 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEAGDMFB_01938 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEAGDMFB_01939 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MEAGDMFB_01940 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEAGDMFB_01941 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MEAGDMFB_01942 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEAGDMFB_01943 0.0 XK27_09800 I Acyltransferase
MEAGDMFB_01944 2.8e-35 XK27_09805 S MORN repeat protein
MEAGDMFB_01945 2.2e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEAGDMFB_01946 4.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEAGDMFB_01947 6.5e-90 adk 2.7.4.3 F topology modulation protein
MEAGDMFB_01948 4.3e-198 ltrA S Low temperature requirement protein
MEAGDMFB_01949 4.9e-60 K sequence-specific DNA binding
MEAGDMFB_01950 1.8e-78 S membrane protein of uknown function UCP014873
MEAGDMFB_01951 5.1e-82 S Short repeat of unknown function (DUF308)
MEAGDMFB_01952 5.5e-89 K sequence-specific DNA binding
MEAGDMFB_01953 3.1e-157 L Replication initiation factor
MEAGDMFB_01954 1.4e-18 S Domain of unknown function (DUF3173)
MEAGDMFB_01955 3.2e-214 int L Belongs to the 'phage' integrase family
MEAGDMFB_01957 4.8e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MEAGDMFB_01958 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MEAGDMFB_01959 6.3e-44 yrzL S Belongs to the UPF0297 family
MEAGDMFB_01960 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEAGDMFB_01961 3.2e-44 yrzB S Belongs to the UPF0473 family
MEAGDMFB_01962 9.5e-292 ccs S the current gene model (or a revised gene model) may contain a frame shift
MEAGDMFB_01963 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MEAGDMFB_01964 7.5e-14
MEAGDMFB_01965 1.6e-88 XK27_10930 K acetyltransferase
MEAGDMFB_01966 3.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEAGDMFB_01967 3.6e-123 yaaA S Belongs to the UPF0246 family
MEAGDMFB_01968 9.3e-167 XK27_01785 S cog cog1284
MEAGDMFB_01969 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEAGDMFB_01971 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
MEAGDMFB_01972 1.8e-26 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_01973 4.4e-130 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
MEAGDMFB_01974 5.6e-219 metE 2.1.1.14 E Methionine synthase
MEAGDMFB_01975 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEAGDMFB_01976 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEAGDMFB_01977 4.3e-127 P ATPases associated with a variety of cellular activities
MEAGDMFB_01978 2e-231
MEAGDMFB_01979 5.2e-281 L DNA integration
MEAGDMFB_01981 3.2e-197 L Replication initiation factor
MEAGDMFB_01982 6.4e-62
MEAGDMFB_01983 6.8e-14
MEAGDMFB_01985 3.4e-65
MEAGDMFB_01986 5.4e-121 S Fic/DOC family N-terminal
MEAGDMFB_01987 3.3e-28
MEAGDMFB_01990 7.4e-80
MEAGDMFB_01991 2.9e-46 K DNA-binding protein
MEAGDMFB_01995 2.7e-121 D ftsk spoiiie
MEAGDMFB_01996 2.1e-206 S Replication initiation factor
MEAGDMFB_01997 2.8e-28 S MerR HTH family regulatory protein
MEAGDMFB_01998 6.8e-221 sip L Belongs to the 'phage' integrase family
MEAGDMFB_01999 7.3e-61 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
MEAGDMFB_02000 1.3e-92 L Transposase
MEAGDMFB_02001 9.5e-47 fruR K transcriptional
MEAGDMFB_02002 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MEAGDMFB_02003 5.8e-162 T Diguanylate cyclase
MEAGDMFB_02005 4.9e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MEAGDMFB_02006 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
MEAGDMFB_02007 0.0
MEAGDMFB_02008 4.3e-07
MEAGDMFB_02011 1.2e-114 nudL L hydrolase
MEAGDMFB_02012 1.8e-53 K transcriptional regulator, PadR family
MEAGDMFB_02013 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
MEAGDMFB_02014 7.4e-107 S Putative adhesin
MEAGDMFB_02015 4.7e-159 XK27_06930 V domain protein
MEAGDMFB_02016 4.6e-94 XK27_06935 K transcriptional regulator
MEAGDMFB_02017 3.5e-53 ypaA M Membrane
MEAGDMFB_02018 1.1e-10
MEAGDMFB_02019 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEAGDMFB_02020 1.8e-47 veg S Biofilm formation stimulator VEG
MEAGDMFB_02021 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEAGDMFB_02022 2.2e-73 rplI J binds to the 23S rRNA
MEAGDMFB_02023 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MEAGDMFB_02024 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEAGDMFB_02025 5.9e-68 yvbG U UPF0056 membrane protein
MEAGDMFB_02026 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEAGDMFB_02027 2.8e-310 S Bacterial membrane protein, YfhO
MEAGDMFB_02028 6.6e-61 isaA GH23 M Immunodominant staphylococcal antigen A
MEAGDMFB_02029 2e-71 lytE M LysM domain protein
MEAGDMFB_02030 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAGDMFB_02031 8.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAGDMFB_02032 5.3e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAGDMFB_02033 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEAGDMFB_02034 5.7e-131 S sequence-specific DNA binding
MEAGDMFB_02035 7.5e-236 ymfH S Peptidase M16
MEAGDMFB_02036 1.1e-228 ymfF S Peptidase M16
MEAGDMFB_02037 6.4e-58 yaaA S S4 domain protein YaaA
MEAGDMFB_02038 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEAGDMFB_02039 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEAGDMFB_02040 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MEAGDMFB_02041 7.1e-153 yvjA S membrane
MEAGDMFB_02042 4.3e-305 ybiT S abc transporter atp-binding protein
MEAGDMFB_02043 0.0 XK27_10405 S Bacterial membrane protein YfhO
MEAGDMFB_02047 3.4e-118 yoaK S Protein of unknown function (DUF1275)
MEAGDMFB_02048 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEAGDMFB_02049 1.5e-204 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MEAGDMFB_02050 2.9e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)