ORF_ID e_value Gene_name EC_number CAZy COGs Description
GBLFDKCK_00001 1.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GBLFDKCK_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GBLFDKCK_00003 1.1e-29 yyzM S Protein conserved in bacteria
GBLFDKCK_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GBLFDKCK_00005 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GBLFDKCK_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GBLFDKCK_00007 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GBLFDKCK_00008 3e-60 divIC D Septum formation initiator
GBLFDKCK_00010 4.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
GBLFDKCK_00011 5.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GBLFDKCK_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GBLFDKCK_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBLFDKCK_00026 2.6e-10
GBLFDKCK_00032 1.2e-106 mreC M Involved in formation and maintenance of cell shape
GBLFDKCK_00033 7.2e-84 mreD M rod shape-determining protein MreD
GBLFDKCK_00034 8.4e-89 usp 3.5.1.28 CBM50 S CHAP domain
GBLFDKCK_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBLFDKCK_00036 2.5e-217 araT 2.6.1.1 E Aminotransferase
GBLFDKCK_00037 1.6e-140 recO L Involved in DNA repair and RecF pathway recombination
GBLFDKCK_00038 1.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GBLFDKCK_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBLFDKCK_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GBLFDKCK_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBLFDKCK_00042 2.3e-188
GBLFDKCK_00043 1.2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GBLFDKCK_00044 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GBLFDKCK_00045 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GBLFDKCK_00046 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GBLFDKCK_00047 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
GBLFDKCK_00048 9e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GBLFDKCK_00049 3.3e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GBLFDKCK_00050 2.1e-174 1.1.1.169 H Ketopantoate reductase
GBLFDKCK_00051 3.2e-11
GBLFDKCK_00052 2.9e-36
GBLFDKCK_00054 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBLFDKCK_00055 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GBLFDKCK_00056 3.1e-69 argR K Regulates arginine biosynthesis genes
GBLFDKCK_00057 1.9e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GBLFDKCK_00058 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GBLFDKCK_00059 1.9e-77 S Protein of unknown function (DUF3021)
GBLFDKCK_00060 2.4e-69 K LytTr DNA-binding domain
GBLFDKCK_00062 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GBLFDKCK_00064 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GBLFDKCK_00065 2.2e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
GBLFDKCK_00066 5e-232 cinA 3.5.1.42 S Belongs to the CinA family
GBLFDKCK_00067 6.1e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBLFDKCK_00068 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
GBLFDKCK_00074 2.6e-10
GBLFDKCK_00077 1.9e-07
GBLFDKCK_00082 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBLFDKCK_00083 4.3e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GBLFDKCK_00084 5.5e-36 XK27_02060 S Transglycosylase associated protein
GBLFDKCK_00085 3.9e-72 badR K Transcriptional regulator, marr family
GBLFDKCK_00086 3.2e-95 S reductase
GBLFDKCK_00087 5e-287 ahpF O alkyl hydroperoxide reductase
GBLFDKCK_00088 7.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
GBLFDKCK_00089 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GBLFDKCK_00090 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GBLFDKCK_00091 1.6e-82 S Putative small multi-drug export protein
GBLFDKCK_00092 1.8e-75 ctsR K Belongs to the CtsR family
GBLFDKCK_00093 0.0 clpC O Belongs to the ClpA ClpB family
GBLFDKCK_00094 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GBLFDKCK_00095 7.8e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GBLFDKCK_00096 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GBLFDKCK_00097 5.7e-138 S SseB protein N-terminal domain
GBLFDKCK_00098 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
GBLFDKCK_00101 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GBLFDKCK_00102 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GBLFDKCK_00104 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBLFDKCK_00105 2.7e-91 yacP S RNA-binding protein containing a PIN domain
GBLFDKCK_00106 4.1e-153 degV S DegV family
GBLFDKCK_00108 5.1e-22 K Transcriptional
GBLFDKCK_00109 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBLFDKCK_00110 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
GBLFDKCK_00112 1.2e-101 cadD P cadmium resistance
GBLFDKCK_00113 1.7e-54 cadC K Bacterial regulatory protein, arsR family
GBLFDKCK_00114 2e-18
GBLFDKCK_00115 1.5e-29 K Helix-turn-helix domain
GBLFDKCK_00116 6e-85
GBLFDKCK_00117 3.2e-139 srtB 3.4.22.70 S sortase, SrtB family
GBLFDKCK_00118 3.3e-233 capA M Bacterial capsule synthesis protein
GBLFDKCK_00119 6.1e-39 gcvR T UPF0237 protein
GBLFDKCK_00120 2.3e-243 XK27_08635 S UPF0210 protein
GBLFDKCK_00121 7.3e-132 ais G Phosphoglycerate mutase
GBLFDKCK_00122 8.2e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GBLFDKCK_00123 3.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
GBLFDKCK_00124 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GBLFDKCK_00125 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GBLFDKCK_00126 0.0 dnaK O Heat shock 70 kDa protein
GBLFDKCK_00128 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GBLFDKCK_00129 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GBLFDKCK_00130 5.3e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
GBLFDKCK_00131 7.4e-80 hmpT S cog cog4720
GBLFDKCK_00144 2.3e-87 sigH K DNA-templated transcription, initiation
GBLFDKCK_00145 6.9e-139 ykuT M mechanosensitive ion channel
GBLFDKCK_00146 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GBLFDKCK_00147 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GBLFDKCK_00148 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GBLFDKCK_00149 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
GBLFDKCK_00150 1.1e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
GBLFDKCK_00151 2.5e-83 XK27_02675 K Acetyltransferase GNAT Family
GBLFDKCK_00152 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
GBLFDKCK_00153 3.4e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GBLFDKCK_00154 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GBLFDKCK_00155 9.1e-83 nrdI F Belongs to the NrdI family
GBLFDKCK_00156 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBLFDKCK_00157 2.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GBLFDKCK_00158 1.9e-121 L Helix-turn-helix domain
GBLFDKCK_00159 3.7e-141 L Integrase core domain protein
GBLFDKCK_00160 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
GBLFDKCK_00161 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBLFDKCK_00162 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GBLFDKCK_00163 2.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GBLFDKCK_00164 2.9e-194 yhjX P Major Facilitator
GBLFDKCK_00165 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GBLFDKCK_00166 1.8e-83 V VanZ like family
GBLFDKCK_00167 1.1e-182 D nuclear chromosome segregation
GBLFDKCK_00168 2.2e-123 glnQ E abc transporter atp-binding protein
GBLFDKCK_00169 6.9e-276 glnP P ABC transporter
GBLFDKCK_00170 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GBLFDKCK_00171 4.4e-19 S Protein of unknown function (DUF3021)
GBLFDKCK_00172 2.3e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GBLFDKCK_00173 1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
GBLFDKCK_00174 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GBLFDKCK_00175 6.3e-235 sufD O assembly protein SufD
GBLFDKCK_00176 1.7e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBLFDKCK_00177 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
GBLFDKCK_00178 1e-273 sufB O assembly protein SufB
GBLFDKCK_00179 4.6e-311 oppA E ABC transporter substrate-binding protein
GBLFDKCK_00180 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBLFDKCK_00181 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBLFDKCK_00182 6.6e-198 oppD P Belongs to the ABC transporter superfamily
GBLFDKCK_00183 4.1e-167 oppF P Belongs to the ABC transporter superfamily
GBLFDKCK_00184 2.7e-26
GBLFDKCK_00185 6.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GBLFDKCK_00186 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBLFDKCK_00187 5.9e-71 adcR K transcriptional
GBLFDKCK_00188 9.2e-135 adcC P ABC transporter, ATP-binding protein
GBLFDKCK_00189 5.6e-128 adcB P ABC transporter (Permease
GBLFDKCK_00190 4.5e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
GBLFDKCK_00191 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBLFDKCK_00192 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
GBLFDKCK_00193 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
GBLFDKCK_00194 2.2e-154 Z012_04635 K sequence-specific DNA binding
GBLFDKCK_00195 4.8e-285 V ABC transporter
GBLFDKCK_00196 9.4e-127 yeeN K transcriptional regulatory protein
GBLFDKCK_00197 3.1e-48 yajC U protein transport
GBLFDKCK_00198 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBLFDKCK_00199 8.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
GBLFDKCK_00200 4.7e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GBLFDKCK_00201 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GBLFDKCK_00202 0.0 WQ51_06230 S ABC transporter
GBLFDKCK_00203 1.4e-142 cmpC S abc transporter atp-binding protein
GBLFDKCK_00204 2.7e-40 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GBLFDKCK_00205 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GBLFDKCK_00207 1e-42
GBLFDKCK_00208 7.6e-55 S TM2 domain
GBLFDKCK_00209 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GBLFDKCK_00210 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBLFDKCK_00211 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GBLFDKCK_00212 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
GBLFDKCK_00213 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
GBLFDKCK_00214 2.4e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
GBLFDKCK_00215 5.6e-144 cof S Sucrose-6F-phosphate phosphohydrolase
GBLFDKCK_00216 1.5e-135 glcR K transcriptional regulator (DeoR family)
GBLFDKCK_00217 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GBLFDKCK_00218 2.9e-73 K transcriptional
GBLFDKCK_00219 6.8e-234 S COG1073 Hydrolases of the alpha beta superfamily
GBLFDKCK_00220 2.3e-151 cylA V abc transporter atp-binding protein
GBLFDKCK_00221 1.8e-129 cylB V ABC-2 type transporter
GBLFDKCK_00222 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
GBLFDKCK_00223 1.8e-32 S Protein of unknown function (DUF3021)
GBLFDKCK_00224 1.4e-122 mta K Transcriptional
GBLFDKCK_00225 5.6e-121 yhcA V abc transporter atp-binding protein
GBLFDKCK_00226 6.3e-214 macB_2 V FtsX-like permease family
GBLFDKCK_00227 1.8e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GBLFDKCK_00228 3.8e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GBLFDKCK_00229 1.7e-73 yhaI S Protein of unknown function (DUF805)
GBLFDKCK_00230 1.3e-254 pepC 3.4.22.40 E aminopeptidase
GBLFDKCK_00231 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBLFDKCK_00232 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GBLFDKCK_00233 5.8e-94 ypsA S Belongs to the UPF0398 family
GBLFDKCK_00234 1.6e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GBLFDKCK_00235 9.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GBLFDKCK_00236 2.1e-269 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GBLFDKCK_00237 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
GBLFDKCK_00238 7.4e-23
GBLFDKCK_00239 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GBLFDKCK_00240 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
GBLFDKCK_00241 1.6e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBLFDKCK_00242 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GBLFDKCK_00243 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBLFDKCK_00244 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GBLFDKCK_00245 4.6e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBLFDKCK_00246 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
GBLFDKCK_00247 6.9e-103 ybhL S Belongs to the BI1 family
GBLFDKCK_00249 9.2e-10 ycdA S Domain of unknown function (DUF4352)
GBLFDKCK_00250 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GBLFDKCK_00251 1.4e-90 K transcriptional regulator
GBLFDKCK_00252 1.6e-36 yneF S UPF0154 protein
GBLFDKCK_00253 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GBLFDKCK_00254 2.1e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GBLFDKCK_00255 8.7e-98 XK27_09740 S Phosphoesterase
GBLFDKCK_00256 8.3e-87 ykuL S CBS domain
GBLFDKCK_00257 1e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GBLFDKCK_00258 5.9e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GBLFDKCK_00259 1.9e-93 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GBLFDKCK_00260 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBLFDKCK_00261 5.1e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GBLFDKCK_00262 9.3e-259 trkH P Cation transport protein
GBLFDKCK_00263 1e-246 trkA P Potassium transporter peripheral membrane component
GBLFDKCK_00264 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GBLFDKCK_00265 7.1e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GBLFDKCK_00266 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
GBLFDKCK_00267 2.3e-53 S Bacterial protein of unknown function (DUF961)
GBLFDKCK_00268 4.2e-65 S Bacterial protein of unknown function (DUF961)
GBLFDKCK_00269 8.1e-268 D FtsK/SpoIIIE family
GBLFDKCK_00270 8e-221 K Replication initiation factor
GBLFDKCK_00271 1.9e-30 S Psort location CytoplasmicMembrane, score
GBLFDKCK_00272 3.7e-90 S Antirestriction protein (ArdA)
GBLFDKCK_00273 1.4e-68 S TcpE family
GBLFDKCK_00274 0.0 S AAA-like domain
GBLFDKCK_00275 0.0 S the current gene model (or a revised gene model) may contain a frame shift
GBLFDKCK_00276 5.8e-191 yddH M Lysozyme-like
GBLFDKCK_00277 2.4e-167 S Conjugative transposon protein TcpC
GBLFDKCK_00278 0.0 tetP J Elongation Factor G, domain II
GBLFDKCK_00279 2.3e-57 K Helix-turn-helix domain
GBLFDKCK_00280 1.5e-71 phyR K Sigma-70, region 4
GBLFDKCK_00281 5.5e-36 S Helix-turn-helix domain
GBLFDKCK_00282 1e-30 xis S Excisionase from transposon Tn916
GBLFDKCK_00283 1.3e-234 L Belongs to the 'phage' integrase family
GBLFDKCK_00284 1.8e-27 L Transposase (IS116 IS110 IS902 family)
GBLFDKCK_00285 2.5e-153 K sequence-specific DNA binding
GBLFDKCK_00286 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GBLFDKCK_00287 1.3e-54 yhaI L Membrane
GBLFDKCK_00288 1.2e-255 S Domain of unknown function (DUF4173)
GBLFDKCK_00289 6.8e-95 ureI S AmiS/UreI family transporter
GBLFDKCK_00290 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GBLFDKCK_00291 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GBLFDKCK_00292 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GBLFDKCK_00293 6.6e-78 ureE O enzyme active site formation
GBLFDKCK_00294 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GBLFDKCK_00295 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GBLFDKCK_00296 3.1e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GBLFDKCK_00297 2.1e-177 cbiM P PDGLE domain
GBLFDKCK_00298 7.5e-138 P cobalt transport protein
GBLFDKCK_00299 6.3e-131 cbiO P ABC transporter
GBLFDKCK_00300 1.1e-137 ET ABC transporter substrate-binding protein
GBLFDKCK_00301 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
GBLFDKCK_00302 5.9e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GBLFDKCK_00303 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBLFDKCK_00304 1.2e-99 metI P ABC transporter (Permease
GBLFDKCK_00305 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GBLFDKCK_00306 1.2e-120 ktrA P COG0569 K transport systems, NAD-binding component
GBLFDKCK_00307 2.9e-238 P COG0168 Trk-type K transport systems, membrane components
GBLFDKCK_00308 1.5e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
GBLFDKCK_00309 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
GBLFDKCK_00310 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBLFDKCK_00311 3.2e-281 T PhoQ Sensor
GBLFDKCK_00312 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GBLFDKCK_00313 1.6e-216 dnaB L Replication initiation and membrane attachment
GBLFDKCK_00314 1.5e-166 dnaI L Primosomal protein DnaI
GBLFDKCK_00315 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GBLFDKCK_00316 3.2e-107
GBLFDKCK_00317 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBLFDKCK_00318 2.5e-62 manO S protein conserved in bacteria
GBLFDKCK_00319 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
GBLFDKCK_00320 2.6e-117 manM G pts system
GBLFDKCK_00321 4.9e-174 manL 2.7.1.191 G pts system
GBLFDKCK_00322 2e-67 manO S Protein conserved in bacteria
GBLFDKCK_00323 1.9e-164 manN G PTS system mannose fructose sorbose family IID component
GBLFDKCK_00324 4.7e-135 manY G pts system
GBLFDKCK_00325 1.6e-169 manL 2.7.1.191 G pts system
GBLFDKCK_00326 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
GBLFDKCK_00327 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GBLFDKCK_00328 5.6e-248 pbuO S permease
GBLFDKCK_00329 2.5e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
GBLFDKCK_00330 2.4e-92 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
GBLFDKCK_00331 6.7e-213 brpA K Transcriptional
GBLFDKCK_00332 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
GBLFDKCK_00333 2.4e-196 nusA K Participates in both transcription termination and antitermination
GBLFDKCK_00334 2.7e-48 ylxR K Nucleic-acid-binding protein implicated in transcription termination
GBLFDKCK_00335 1.5e-46 ylxQ J ribosomal protein
GBLFDKCK_00336 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GBLFDKCK_00337 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GBLFDKCK_00338 1.4e-101 yvdD 3.2.2.10 S Belongs to the LOG family
GBLFDKCK_00339 6e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBLFDKCK_00340 4.3e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
GBLFDKCK_00341 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
GBLFDKCK_00342 3.3e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
GBLFDKCK_00343 4.3e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GBLFDKCK_00344 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GBLFDKCK_00345 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
GBLFDKCK_00346 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GBLFDKCK_00347 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GBLFDKCK_00348 1.4e-72 ylbF S Belongs to the UPF0342 family
GBLFDKCK_00349 1.9e-46 ylbG S UPF0298 protein
GBLFDKCK_00350 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GBLFDKCK_00351 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
GBLFDKCK_00352 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
GBLFDKCK_00353 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GBLFDKCK_00354 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GBLFDKCK_00355 3e-111 acuB S CBS domain
GBLFDKCK_00356 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GBLFDKCK_00357 2.9e-108 yvyE 3.4.13.9 S YigZ family
GBLFDKCK_00358 1.6e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GBLFDKCK_00359 7.7e-83 comFC K competence protein
GBLFDKCK_00360 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GBLFDKCK_00368 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
GBLFDKCK_00369 1.4e-107 S Domain of unknown function (DUF1803)
GBLFDKCK_00370 7.8e-102 ygaC J Belongs to the UPF0374 family
GBLFDKCK_00371 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
GBLFDKCK_00372 7.7e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBLFDKCK_00373 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
GBLFDKCK_00374 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
GBLFDKCK_00375 2.8e-114 S HAD hydrolase, family IA, variant 3
GBLFDKCK_00376 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
GBLFDKCK_00377 5.2e-72 marR K Transcriptional regulator, MarR family
GBLFDKCK_00378 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBLFDKCK_00379 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBLFDKCK_00380 7.5e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
GBLFDKCK_00381 1.4e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GBLFDKCK_00382 1.8e-125 IQ reductase
GBLFDKCK_00383 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GBLFDKCK_00384 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GBLFDKCK_00385 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GBLFDKCK_00386 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GBLFDKCK_00387 2.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GBLFDKCK_00388 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GBLFDKCK_00389 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GBLFDKCK_00390 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
GBLFDKCK_00391 4e-112 fruR K transcriptional
GBLFDKCK_00392 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GBLFDKCK_00393 0.0 fruA 2.7.1.202 G phosphotransferase system
GBLFDKCK_00394 1.1e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBLFDKCK_00395 1.2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GBLFDKCK_00397 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GBLFDKCK_00398 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GBLFDKCK_00399 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GBLFDKCK_00400 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GBLFDKCK_00401 5.8e-97 2.3.1.128 K acetyltransferase
GBLFDKCK_00402 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GBLFDKCK_00403 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GBLFDKCK_00404 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GBLFDKCK_00405 5e-63 WQ51_03320 S cog cog4835
GBLFDKCK_00406 2.9e-151 XK27_08360 S EDD domain protein, DegV family
GBLFDKCK_00407 1.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GBLFDKCK_00408 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GBLFDKCK_00409 0.0 yfmR S abc transporter atp-binding protein
GBLFDKCK_00410 5e-26 U response to pH
GBLFDKCK_00411 1.5e-130 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
GBLFDKCK_00412 1.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
GBLFDKCK_00413 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GBLFDKCK_00414 6.2e-283 S Psort location CytoplasmicMembrane, score
GBLFDKCK_00415 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GBLFDKCK_00416 1.3e-73 K DNA-binding transcription factor activity
GBLFDKCK_00417 0.0 lmrA1 V abc transporter atp-binding protein
GBLFDKCK_00418 0.0 lmrA2 V abc transporter atp-binding protein
GBLFDKCK_00419 1.8e-113 K Acetyltransferase (GNAT) family
GBLFDKCK_00420 1.1e-112 2.7.6.5 S Region found in RelA / SpoT proteins
GBLFDKCK_00421 4.9e-117 T response regulator
GBLFDKCK_00422 1.8e-215 sptS 2.7.13.3 T Histidine kinase
GBLFDKCK_00423 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GBLFDKCK_00424 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GBLFDKCK_00425 2.2e-159 cvfB S Protein conserved in bacteria
GBLFDKCK_00426 3.7e-34 yozE S Belongs to the UPF0346 family
GBLFDKCK_00427 6.2e-134 sip M LysM domain protein
GBLFDKCK_00428 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
GBLFDKCK_00433 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBLFDKCK_00434 9.6e-163 S reductase
GBLFDKCK_00435 4.7e-168 K transcriptional regulator (lysR family)
GBLFDKCK_00436 2.7e-105 S CAAX amino terminal protease family protein
GBLFDKCK_00437 5.1e-308 S Glucan-binding protein C
GBLFDKCK_00438 7.3e-163 S CHAP domain
GBLFDKCK_00439 1.3e-55 insK L Integrase core domain protein
GBLFDKCK_00440 4.4e-77 L transposition
GBLFDKCK_00441 7.5e-180 coiA 3.6.4.12 S Competence protein
GBLFDKCK_00442 0.0 pepF E oligoendopeptidase F
GBLFDKCK_00443 1e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
GBLFDKCK_00444 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
GBLFDKCK_00445 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
GBLFDKCK_00446 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GBLFDKCK_00456 3.4e-115 V ATPases associated with a variety of cellular activities
GBLFDKCK_00457 1.1e-119
GBLFDKCK_00458 5.2e-232 2.7.13.3 T GHKL domain
GBLFDKCK_00459 1.7e-134 agrA KT Response regulator of the LytR AlgR family
GBLFDKCK_00461 6.1e-64 K sequence-specific DNA binding
GBLFDKCK_00462 1.2e-09
GBLFDKCK_00464 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
GBLFDKCK_00465 2.2e-60 agrA KT response regulator
GBLFDKCK_00466 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBLFDKCK_00467 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
GBLFDKCK_00468 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GBLFDKCK_00469 4.6e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBLFDKCK_00470 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GBLFDKCK_00471 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GBLFDKCK_00472 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GBLFDKCK_00473 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GBLFDKCK_00474 2.5e-215 ftsW D Belongs to the SEDS family
GBLFDKCK_00475 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GBLFDKCK_00476 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GBLFDKCK_00477 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBLFDKCK_00479 2.4e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GBLFDKCK_00480 9.6e-158 holB 2.7.7.7 L dna polymerase iii
GBLFDKCK_00481 8.9e-134 yaaT S stage 0 sporulation protein
GBLFDKCK_00482 1.2e-54 yabA L Involved in initiation control of chromosome replication
GBLFDKCK_00483 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GBLFDKCK_00484 1.9e-228 amt P Ammonium Transporter
GBLFDKCK_00485 1.9e-53 glnB K Belongs to the P(II) protein family
GBLFDKCK_00486 1.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
GBLFDKCK_00487 7.4e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
GBLFDKCK_00488 6.9e-82 S Bacterial inner membrane protein
GBLFDKCK_00489 4e-113 3.4.17.14, 3.5.1.28 NU amidase activity
GBLFDKCK_00490 1.9e-292 nptA P COG1283 Na phosphate symporter
GBLFDKCK_00491 1.8e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GBLFDKCK_00492 5.3e-218 S membrane
GBLFDKCK_00493 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GBLFDKCK_00494 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GBLFDKCK_00495 5e-38 ynzC S UPF0291 protein
GBLFDKCK_00496 1.1e-253 cycA E permease
GBLFDKCK_00497 2.2e-10 uvrX 2.7.7.7 L impB/mucB/samB family
GBLFDKCK_00498 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBLFDKCK_00499 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBLFDKCK_00501 5.1e-73 K Helix-turn-helix
GBLFDKCK_00503 1.5e-166 fhuR K transcriptional regulator (lysR family)
GBLFDKCK_00504 9.8e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GBLFDKCK_00505 2.2e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GBLFDKCK_00506 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GBLFDKCK_00507 1.6e-222 pyrP F uracil Permease
GBLFDKCK_00508 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GBLFDKCK_00509 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
GBLFDKCK_00510 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
GBLFDKCK_00511 9.9e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
GBLFDKCK_00512 1.5e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBLFDKCK_00513 3.1e-122 macB V ABC transporter, ATP-binding protein
GBLFDKCK_00514 3.6e-203 V permease protein
GBLFDKCK_00515 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GBLFDKCK_00516 4.6e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GBLFDKCK_00517 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBLFDKCK_00518 1.2e-114 K Psort location Cytoplasmic, score
GBLFDKCK_00521 4.6e-111 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBLFDKCK_00522 1.7e-134 fhuB P FecCD transport family
GBLFDKCK_00523 1.2e-121 fhuD P ABC transporter, substratebinding protein
GBLFDKCK_00524 1.1e-109 fhuC 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GBLFDKCK_00525 9.8e-47 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBLFDKCK_00526 9.9e-16 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GBLFDKCK_00527 0.0 mdlB V abc transporter atp-binding protein
GBLFDKCK_00528 0.0 lmrA V abc transporter atp-binding protein
GBLFDKCK_00529 3.3e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GBLFDKCK_00530 1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GBLFDKCK_00531 9e-197 yceA S Belongs to the UPF0176 family
GBLFDKCK_00532 1.6e-28 XK27_00085 K Transcriptional
GBLFDKCK_00533 4.8e-21
GBLFDKCK_00534 5.2e-131 deoD_1 2.4.2.3 F Phosphorylase superfamily
GBLFDKCK_00535 3.9e-114 S VIT family
GBLFDKCK_00536 5.3e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBLFDKCK_00537 2.1e-213 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GBLFDKCK_00539 3.7e-199 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GBLFDKCK_00542 4.1e-139 E Alpha beta hydrolase
GBLFDKCK_00543 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBLFDKCK_00544 8.5e-99 GBS0088 J protein conserved in bacteria
GBLFDKCK_00545 1.4e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GBLFDKCK_00546 5e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GBLFDKCK_00547 3.6e-161 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GBLFDKCK_00548 1.8e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GBLFDKCK_00549 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GBLFDKCK_00550 2.4e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GBLFDKCK_00551 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
GBLFDKCK_00552 2e-26
GBLFDKCK_00553 1.2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GBLFDKCK_00554 0.0 U protein secretion
GBLFDKCK_00555 2.2e-190 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
GBLFDKCK_00556 2.6e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GBLFDKCK_00557 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBLFDKCK_00558 1.2e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBLFDKCK_00559 1.1e-200 S Protein of unknown function (DUF3114)
GBLFDKCK_00560 4.1e-29 pspC KT PspC domain protein
GBLFDKCK_00561 5.2e-119 yqfA K protein, Hemolysin III
GBLFDKCK_00562 3e-78 K hmm pf08876
GBLFDKCK_00563 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GBLFDKCK_00564 1.3e-215 mvaS 2.3.3.10 I synthase
GBLFDKCK_00565 5.9e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GBLFDKCK_00566 8.1e-93 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GBLFDKCK_00567 9.7e-22
GBLFDKCK_00568 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GBLFDKCK_00569 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
GBLFDKCK_00570 2.3e-251 mmuP E amino acid
GBLFDKCK_00571 1.5e-169 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
GBLFDKCK_00572 2.2e-30 S Domain of unknown function (DUF1912)
GBLFDKCK_00573 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
GBLFDKCK_00574 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GBLFDKCK_00575 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBLFDKCK_00577 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBLFDKCK_00578 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
GBLFDKCK_00579 4.8e-16 S Protein of unknown function (DUF2969)
GBLFDKCK_00582 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
GBLFDKCK_00585 4.2e-107 S Domain of Unknown Function with PDB structure (DUF3862)
GBLFDKCK_00586 3.8e-117 M Pfam SNARE associated Golgi protein
GBLFDKCK_00587 2.8e-187 murN 2.3.2.16 V FemAB family
GBLFDKCK_00588 1.8e-173 S oxidoreductase
GBLFDKCK_00589 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
GBLFDKCK_00590 2.8e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GBLFDKCK_00591 0.0 clpE O Belongs to the ClpA ClpB family
GBLFDKCK_00592 6.9e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBLFDKCK_00593 1e-34 ykuJ S protein conserved in bacteria
GBLFDKCK_00594 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
GBLFDKCK_00595 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_00596 3.1e-78 feoA P FeoA domain protein
GBLFDKCK_00597 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GBLFDKCK_00598 6.6e-08
GBLFDKCK_00599 1.3e-150 I Alpha/beta hydrolase family
GBLFDKCK_00600 4.5e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBLFDKCK_00601 1.5e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GBLFDKCK_00602 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
GBLFDKCK_00603 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GBLFDKCK_00604 2.2e-151 licT K antiterminator
GBLFDKCK_00605 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBLFDKCK_00606 2.6e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GBLFDKCK_00607 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GBLFDKCK_00608 7.6e-149 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GBLFDKCK_00609 3e-94 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GBLFDKCK_00610 2.2e-221 mdtG EGP Major facilitator Superfamily
GBLFDKCK_00611 2e-33 secG U Preprotein translocase subunit SecG
GBLFDKCK_00612 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GBLFDKCK_00613 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GBLFDKCK_00614 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBLFDKCK_00615 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
GBLFDKCK_00616 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
GBLFDKCK_00617 1.2e-180 ccpA K Catabolite control protein A
GBLFDKCK_00618 2.9e-201 yyaQ S YjbR
GBLFDKCK_00619 4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GBLFDKCK_00620 3.9e-78 yueI S Protein of unknown function (DUF1694)
GBLFDKCK_00621 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GBLFDKCK_00622 1.2e-25 WQ51_00785
GBLFDKCK_00623 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GBLFDKCK_00624 3.8e-218 ywbD 2.1.1.191 J Methyltransferase
GBLFDKCK_00625 7.5e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GBLFDKCK_00626 4.2e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GBLFDKCK_00627 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GBLFDKCK_00628 2.2e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GBLFDKCK_00629 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GBLFDKCK_00630 4.2e-53 yheA S Belongs to the UPF0342 family
GBLFDKCK_00631 3.3e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GBLFDKCK_00632 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GBLFDKCK_00633 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GBLFDKCK_00634 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
GBLFDKCK_00635 6.4e-244 msrR K Transcriptional regulator
GBLFDKCK_00636 7.6e-153 ydiA P C4-dicarboxylate transporter malic acid transport protein
GBLFDKCK_00637 5.5e-200 I acyl-CoA dehydrogenase
GBLFDKCK_00638 2e-97 mip S hydroperoxide reductase activity
GBLFDKCK_00639 3.2e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBLFDKCK_00640 4.3e-22
GBLFDKCK_00641 2e-217 EGP Transmembrane secretion effector
GBLFDKCK_00642 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
GBLFDKCK_00643 1.1e-49
GBLFDKCK_00644 8.7e-60
GBLFDKCK_00645 5.9e-55
GBLFDKCK_00646 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBLFDKCK_00647 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
GBLFDKCK_00648 1.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
GBLFDKCK_00649 1.6e-61 smtB K Transcriptional regulator
GBLFDKCK_00650 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GBLFDKCK_00652 2e-130 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBLFDKCK_00653 6.4e-131 S Domain of unknown function (DUF4336)
GBLFDKCK_00654 7e-204 yeaN P transporter
GBLFDKCK_00655 4.6e-149 yitS S EDD domain protein, DegV family
GBLFDKCK_00656 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
GBLFDKCK_00657 2.3e-113 cutC P Participates in the control of copper homeostasis
GBLFDKCK_00658 0.0 M family 8
GBLFDKCK_00659 9.2e-267 L Transposase
GBLFDKCK_00660 3.5e-292 norB P Major facilitator superfamily
GBLFDKCK_00661 1.9e-95 tetR K transcriptional regulator
GBLFDKCK_00662 1.1e-155 S Domain of unknown function (DUF4300)
GBLFDKCK_00663 9.2e-125 V CAAX protease self-immunity
GBLFDKCK_00664 4.8e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBLFDKCK_00665 1.1e-136 fecE 3.6.3.34 HP ABC transporter
GBLFDKCK_00666 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GBLFDKCK_00667 2.1e-131 ybbA S Putative esterase
GBLFDKCK_00668 2.9e-81 Q Methyltransferase domain
GBLFDKCK_00669 8e-24 K TetR family transcriptional regulator
GBLFDKCK_00670 2.1e-43 K TetR family transcriptional regulator
GBLFDKCK_00671 6.4e-48
GBLFDKCK_00672 8.6e-123 V CAAX protease self-immunity
GBLFDKCK_00673 6.8e-11
GBLFDKCK_00674 1.7e-19 S Bacterial lipoprotein
GBLFDKCK_00675 5.4e-60 S Protein of unknown function (DUF1722)
GBLFDKCK_00676 5.2e-65 yqeB S Pyrimidine dimer DNA glycosylase
GBLFDKCK_00678 9.4e-51
GBLFDKCK_00679 4.7e-95 S CAAX protease self-immunity
GBLFDKCK_00680 1.4e-118 estA E GDSL-like Lipase/Acylhydrolase
GBLFDKCK_00681 5.2e-102
GBLFDKCK_00682 1.3e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
GBLFDKCK_00683 1.9e-147 ycgQ S TIGR03943 family
GBLFDKCK_00684 1.6e-155 XK27_03015 S permease
GBLFDKCK_00686 0.0 yhgF K Transcriptional accessory protein
GBLFDKCK_00687 2.7e-84 ydcK S Belongs to the SprT family
GBLFDKCK_00688 2.2e-41 pspC KT PspC domain
GBLFDKCK_00689 8.6e-165 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GBLFDKCK_00690 9.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GBLFDKCK_00691 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GBLFDKCK_00692 4.2e-69 ytxH S General stress protein
GBLFDKCK_00694 2e-177 yegQ O Peptidase U32
GBLFDKCK_00695 2.9e-251 yegQ O Peptidase U32
GBLFDKCK_00696 7e-50 S CHY zinc finger
GBLFDKCK_00697 3.2e-87 bioY S biotin synthase
GBLFDKCK_00699 1.1e-33 XK27_12190 S protein conserved in bacteria
GBLFDKCK_00700 9.9e-231 mntH P H( )-stimulated, divalent metal cation uptake system
GBLFDKCK_00701 8.7e-13
GBLFDKCK_00702 3.3e-15
GBLFDKCK_00703 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GBLFDKCK_00704 7.1e-138 M LysM domain
GBLFDKCK_00705 8.4e-23
GBLFDKCK_00706 1.5e-174 S hydrolase
GBLFDKCK_00707 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
GBLFDKCK_00708 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBLFDKCK_00709 6.2e-144 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
GBLFDKCK_00710 2e-26 P Hemerythrin HHE cation binding domain protein
GBLFDKCK_00711 1.5e-155 5.2.1.8 G hydrolase
GBLFDKCK_00712 1.8e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBLFDKCK_00713 7.7e-211 MA20_36090 S Protein of unknown function (DUF2974)
GBLFDKCK_00714 2.7e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GBLFDKCK_00715 4.4e-45 S Phage derived protein Gp49-like (DUF891)
GBLFDKCK_00716 6.5e-45 K Helix-turn-helix domain
GBLFDKCK_00717 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GBLFDKCK_00718 8.7e-75 S Protein of unknown function (DUF1524)
GBLFDKCK_00719 2.8e-131 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
GBLFDKCK_00720 9.8e-56 S Phage derived protein Gp49-like (DUF891)
GBLFDKCK_00721 5e-42 K Helix-turn-helix domain
GBLFDKCK_00722 8.6e-31 hsdM 2.1.1.72 V type I restriction-modification system
GBLFDKCK_00723 2.2e-257 hsdM 2.1.1.72 V type I restriction-modification system
GBLFDKCK_00724 1.9e-135 S double-stranded DNA endodeoxyribonuclease activity
GBLFDKCK_00726 0.0 2.4.1.21 GT5 M Right handed beta helix region
GBLFDKCK_00727 4.2e-173 spd F DNA RNA non-specific endonuclease
GBLFDKCK_00728 1e-91 lemA S LemA family
GBLFDKCK_00729 1.3e-133 htpX O Belongs to the peptidase M48B family
GBLFDKCK_00730 3.8e-119 sirR K iron dependent repressor
GBLFDKCK_00731 4.2e-167 sitA P Belongs to the bacterial solute-binding protein 9 family
GBLFDKCK_00732 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
GBLFDKCK_00733 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
GBLFDKCK_00734 6.7e-73 S Psort location CytoplasmicMembrane, score
GBLFDKCK_00735 4.8e-64 S Domain of unknown function (DUF4430)
GBLFDKCK_00736 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GBLFDKCK_00737 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
GBLFDKCK_00738 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
GBLFDKCK_00739 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
GBLFDKCK_00740 7.5e-115 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GBLFDKCK_00741 9.3e-92 dps P Belongs to the Dps family
GBLFDKCK_00742 5.2e-83 perR P Belongs to the Fur family
GBLFDKCK_00743 2.4e-27 yqgQ S protein conserved in bacteria
GBLFDKCK_00744 3.5e-177 glk 2.7.1.2 G Glucokinase
GBLFDKCK_00745 0.0 typA T GTP-binding protein TypA
GBLFDKCK_00747 2.3e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GBLFDKCK_00748 1.9e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBLFDKCK_00749 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GBLFDKCK_00750 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GBLFDKCK_00751 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GBLFDKCK_00752 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GBLFDKCK_00753 3.2e-101 sepF D cell septum assembly
GBLFDKCK_00754 6.5e-30 yggT D integral membrane protein
GBLFDKCK_00755 2.7e-143 ylmH S conserved protein, contains S4-like domain
GBLFDKCK_00756 3.2e-137 divIVA D Cell division initiation protein
GBLFDKCK_00757 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBLFDKCK_00758 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBLFDKCK_00759 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBLFDKCK_00760 2.9e-34 nrdH O Glutaredoxin
GBLFDKCK_00761 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GBLFDKCK_00762 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
GBLFDKCK_00763 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
GBLFDKCK_00764 5.1e-38 ptsH G phosphocarrier protein Hpr
GBLFDKCK_00765 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBLFDKCK_00766 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
GBLFDKCK_00767 6.1e-162 XK27_05670 S Putative esterase
GBLFDKCK_00768 2.7e-153 XK27_05675 S Esterase
GBLFDKCK_00769 2.9e-226 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
GBLFDKCK_00770 5.5e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
GBLFDKCK_00771 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GBLFDKCK_00772 0.0 uup S abc transporter atp-binding protein
GBLFDKCK_00773 1.6e-39 MA20_06245 S yiaA/B two helix domain
GBLFDKCK_00774 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
GBLFDKCK_00775 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GBLFDKCK_00776 2.3e-150 cobQ S glutamine amidotransferase
GBLFDKCK_00777 9.9e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
GBLFDKCK_00778 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GBLFDKCK_00779 6e-169 ybbR S Protein conserved in bacteria
GBLFDKCK_00780 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBLFDKCK_00781 5e-64 gtrA S GtrA-like protein
GBLFDKCK_00782 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
GBLFDKCK_00783 2.2e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBLFDKCK_00784 8e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
GBLFDKCK_00785 1.1e-200 yurR 1.4.5.1 E oxidoreductase
GBLFDKCK_00786 2.5e-258 S phospholipase Carboxylesterase
GBLFDKCK_00787 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GBLFDKCK_00788 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GBLFDKCK_00789 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GBLFDKCK_00791 2.9e-30 KT response to antibiotic
GBLFDKCK_00792 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
GBLFDKCK_00793 2.6e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
GBLFDKCK_00794 1.8e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GBLFDKCK_00795 2.5e-115 ylfI S tigr01906
GBLFDKCK_00796 1.3e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
GBLFDKCK_00797 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
GBLFDKCK_00798 2.7e-59 XK27_08085
GBLFDKCK_00799 7.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBLFDKCK_00800 1.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GBLFDKCK_00801 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GBLFDKCK_00802 3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBLFDKCK_00803 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GBLFDKCK_00804 4.7e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GBLFDKCK_00805 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GBLFDKCK_00806 3.6e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GBLFDKCK_00807 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GBLFDKCK_00808 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
GBLFDKCK_00811 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
GBLFDKCK_00812 6.3e-145 P molecular chaperone
GBLFDKCK_00813 1.4e-96 S Carbohydrate-binding domain-containing protein Cthe_2159
GBLFDKCK_00814 3.6e-180 XK27_08075 M glycosyl transferase family 2
GBLFDKCK_00815 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_00816 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_00817 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_00818 1.9e-227 rodA D Belongs to the SEDS family
GBLFDKCK_00819 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBLFDKCK_00820 1.2e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GBLFDKCK_00821 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GBLFDKCK_00822 1.3e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GBLFDKCK_00823 2.8e-131 Q Methyltransferase domain
GBLFDKCK_00824 2.1e-67 GnaT 2.5.1.16 K acetyltransferase
GBLFDKCK_00825 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
GBLFDKCK_00827 3.8e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBLFDKCK_00828 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBLFDKCK_00829 1.1e-124 dnaD
GBLFDKCK_00830 2.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GBLFDKCK_00831 1.8e-06 KT response to antibiotic
GBLFDKCK_00832 8.6e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBLFDKCK_00833 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBLFDKCK_00834 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GBLFDKCK_00835 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GBLFDKCK_00836 8.3e-73 argR K Regulates arginine biosynthesis genes
GBLFDKCK_00837 4.6e-302 recN L May be involved in recombinational repair of damaged DNA
GBLFDKCK_00838 9.3e-150 DegV S DegV family
GBLFDKCK_00839 8.4e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
GBLFDKCK_00840 6.2e-97 ypmS S Protein conserved in bacteria
GBLFDKCK_00841 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GBLFDKCK_00843 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
GBLFDKCK_00844 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GBLFDKCK_00845 5.5e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBLFDKCK_00846 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GBLFDKCK_00847 3.5e-37 ysdA L Membrane
GBLFDKCK_00848 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBLFDKCK_00849 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBLFDKCK_00850 0.0 dnaE 2.7.7.7 L DNA polymerase
GBLFDKCK_00851 4.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GBLFDKCK_00852 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GBLFDKCK_00853 3.8e-18 S Domain of unknown function (DUF4649)
GBLFDKCK_00854 4.3e-178 XK27_08835 S ABC transporter substrate binding protein
GBLFDKCK_00855 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
GBLFDKCK_00856 3.1e-136 XK27_08845 S abc transporter atp-binding protein
GBLFDKCK_00857 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBLFDKCK_00858 4.7e-148 estA CE1 S Esterase
GBLFDKCK_00859 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
GBLFDKCK_00860 2.8e-18 XK27_08880
GBLFDKCK_00861 1e-75 fld C Flavodoxin
GBLFDKCK_00862 3.6e-277 clcA P Chloride transporter, ClC family
GBLFDKCK_00863 4.7e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
GBLFDKCK_00864 7.7e-214 XK27_05110 P Chloride transporter ClC family
GBLFDKCK_00865 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GBLFDKCK_00867 9e-198 S Phage integrase family
GBLFDKCK_00871 1.1e-51 S CD20-like family
GBLFDKCK_00872 2.8e-61 S Pfam:Peptidase_M78
GBLFDKCK_00873 4.4e-51 ps115 K Helix-turn-helix XRE-family like proteins
GBLFDKCK_00877 1.3e-34 S Hypothetical protein (DUF2513)
GBLFDKCK_00878 2e-76
GBLFDKCK_00879 2.3e-08 S ORF6C domain
GBLFDKCK_00882 1.1e-80 M Pilin isopeptide linkage domain protein
GBLFDKCK_00883 1.8e-78 S Siphovirus Gp157
GBLFDKCK_00884 5.6e-124 S AAA domain
GBLFDKCK_00885 1.4e-226 S helicase activity
GBLFDKCK_00886 1.1e-67 S Protein of unknown function (DUF669)
GBLFDKCK_00887 3e-105 S Bifunctional DNA primase/polymerase, N-terminal
GBLFDKCK_00888 3.5e-200 S DNA primase
GBLFDKCK_00890 2.1e-49 S hydrolase activity, acting on ester bonds
GBLFDKCK_00893 1.4e-28 S Protein of unknown function (DUF1642)
GBLFDKCK_00896 1.7e-23 S YopX protein
GBLFDKCK_00898 6.6e-13 S Protein of unknown function (DUF1492)
GBLFDKCK_00899 1.4e-84 S peptidase activity
GBLFDKCK_00900 9.5e-64 L phage terminase small subunit
GBLFDKCK_00901 3.3e-84 S Phage Terminase
GBLFDKCK_00902 4.7e-192 S Phage Terminase
GBLFDKCK_00904 1.5e-198 S Phage portal protein
GBLFDKCK_00905 2e-115 S Clp protease
GBLFDKCK_00906 3.9e-202 S peptidase activity
GBLFDKCK_00907 2e-49 S Phage gp6-like head-tail connector protein
GBLFDKCK_00908 1.5e-61 S Phage head-tail joining protein
GBLFDKCK_00909 6e-65 S exonuclease activity
GBLFDKCK_00910 6.5e-55 S Protein of unknown function (DUF806)
GBLFDKCK_00911 2.7e-98 S Pfam:Phage_TTP_1
GBLFDKCK_00913 0.0 S peptidoglycan catabolic process
GBLFDKCK_00914 1.5e-241 S Phage tail protein
GBLFDKCK_00915 0.0 S peptidoglycan catabolic process
GBLFDKCK_00916 1.4e-143
GBLFDKCK_00917 7.8e-12
GBLFDKCK_00918 3.4e-44
GBLFDKCK_00919 8e-26 hol S Holin, phage phi LC3 family
GBLFDKCK_00920 5.3e-78 S peptidoglycan catabolic process
GBLFDKCK_00922 5.6e-132 K cell adhesion
GBLFDKCK_00923 6.6e-08
GBLFDKCK_00924 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
GBLFDKCK_00925 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GBLFDKCK_00926 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
GBLFDKCK_00927 2.6e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBLFDKCK_00928 3.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GBLFDKCK_00929 9.2e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBLFDKCK_00930 8.9e-76 L Transposase (IS116 IS110 IS902 family)
GBLFDKCK_00931 6.6e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GBLFDKCK_00932 3.2e-136
GBLFDKCK_00934 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
GBLFDKCK_00935 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
GBLFDKCK_00937 2.2e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBLFDKCK_00938 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
GBLFDKCK_00939 1.9e-153 endA F DNA RNA non-specific endonuclease
GBLFDKCK_00940 2.9e-111 tcyB_2 P ABC transporter (permease)
GBLFDKCK_00941 1.4e-93 gltJ P ABC transporter (Permease
GBLFDKCK_00942 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_00943 2.9e-111 tcyB_2 P ABC transporter (permease)
GBLFDKCK_00944 8.4e-94 gltJ P ABC transporter (Permease
GBLFDKCK_00945 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_00946 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBLFDKCK_00947 1e-235 vicK 2.7.13.3 T Histidine kinase
GBLFDKCK_00948 1.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
GBLFDKCK_00949 8.7e-57 S Protein of unknown function (DUF454)
GBLFDKCK_00950 2.6e-206 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
GBLFDKCK_00951 2e-146 yidA S hydrolases of the HAD superfamily
GBLFDKCK_00952 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
GBLFDKCK_00953 1.3e-108 XK27_00120 2.4.2.3 F Phosphorylase superfamily
GBLFDKCK_00954 5.3e-68 ywiB S Domain of unknown function (DUF1934)
GBLFDKCK_00955 0.0 pacL 3.6.3.8 P cation transport ATPase
GBLFDKCK_00956 1.6e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GBLFDKCK_00957 1.1e-155 yjjH S Calcineurin-like phosphoesterase
GBLFDKCK_00958 1.4e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GBLFDKCK_00959 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GBLFDKCK_00960 3.2e-124 ftsE D cell division ATP-binding protein FtsE
GBLFDKCK_00961 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GBLFDKCK_00962 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
GBLFDKCK_00963 1.6e-176 yubA S permease
GBLFDKCK_00964 2.4e-223 G COG0457 FOG TPR repeat
GBLFDKCK_00965 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GBLFDKCK_00966 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GBLFDKCK_00967 1.1e-86 ebsA S Family of unknown function (DUF5322)
GBLFDKCK_00968 9.5e-29 fer C Ferredoxin
GBLFDKCK_00969 2.4e-17 M LysM domain
GBLFDKCK_00970 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GBLFDKCK_00971 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GBLFDKCK_00972 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GBLFDKCK_00973 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GBLFDKCK_00974 1.1e-83 XK27_03610 K Gnat family
GBLFDKCK_00975 7.1e-92 yybC
GBLFDKCK_00976 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GBLFDKCK_00977 7.2e-272 pepV 3.5.1.18 E Dipeptidase
GBLFDKCK_00978 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
GBLFDKCK_00979 1.5e-26 L Transposase (IS116 IS110 IS902 family)
GBLFDKCK_00980 5.2e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
GBLFDKCK_00981 3.6e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
GBLFDKCK_00982 7.2e-116 cps4C M biosynthesis protein
GBLFDKCK_00983 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
GBLFDKCK_00984 1.3e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
GBLFDKCK_00985 1.7e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GBLFDKCK_00986 2.8e-159 licD M LICD family
GBLFDKCK_00987 2e-163 S Glycosyl transferase family 2
GBLFDKCK_00988 4.4e-205 M glycosyl transferase group 1
GBLFDKCK_00989 2.4e-85
GBLFDKCK_00990 2.7e-171 S glycosyl transferase family 2
GBLFDKCK_00991 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GBLFDKCK_00992 0.0 M Polysaccharide biosynthesis protein
GBLFDKCK_00993 3.4e-245 S Polysaccharide biosynthesis protein
GBLFDKCK_00994 1.5e-149 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GBLFDKCK_00995 3.7e-108 pgm G Belongs to the phosphoglycerate mutase family
GBLFDKCK_00996 6.3e-108 G Belongs to the phosphoglycerate mutase family
GBLFDKCK_00997 6.2e-108 G Belongs to the phosphoglycerate mutase family
GBLFDKCK_00998 1.8e-196 S hmm pf01594
GBLFDKCK_00999 5.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GBLFDKCK_01000 4.9e-39 S granule-associated protein
GBLFDKCK_01001 8.8e-287 S unusual protein kinase
GBLFDKCK_01002 2.9e-100 estA E Lysophospholipase L1 and related esterases
GBLFDKCK_01003 6.7e-156 rssA S Phospholipase, patatin family
GBLFDKCK_01004 2.7e-175 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GBLFDKCK_01005 5.6e-250 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GBLFDKCK_01006 3.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBLFDKCK_01007 3.8e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBLFDKCK_01008 1.2e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GBLFDKCK_01009 0.0 S the current gene model (or a revised gene model) may contain a frame shift
GBLFDKCK_01010 2.2e-235 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01011 1.6e-214 hpk9 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01012 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GBLFDKCK_01013 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GBLFDKCK_01014 8.1e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GBLFDKCK_01015 0.0 lpdA 1.8.1.4 C Dehydrogenase
GBLFDKCK_01016 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GBLFDKCK_01017 2.7e-153 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBLFDKCK_01018 1.2e-156 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBLFDKCK_01019 1.2e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
GBLFDKCK_01020 4e-179 fatB P ABC-type enterochelin transport system, periplasmic component
GBLFDKCK_01021 2.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
GBLFDKCK_01022 6.4e-229 ycdB P peroxidase
GBLFDKCK_01023 2.3e-285 ywbL P COG0672 High-affinity Fe2 Pb2 permease
GBLFDKCK_01024 2.4e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBLFDKCK_01025 3e-24 tatA U protein secretion
GBLFDKCK_01027 4.7e-213 msmX P Belongs to the ABC transporter superfamily
GBLFDKCK_01028 9.8e-152 malG P ABC transporter (Permease
GBLFDKCK_01029 1.7e-249 malF P ABC transporter (Permease
GBLFDKCK_01030 1.5e-228 malX G ABC transporter
GBLFDKCK_01031 3.5e-180 malR K Transcriptional regulator
GBLFDKCK_01032 8.6e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
GBLFDKCK_01033 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GBLFDKCK_01034 1e-39
GBLFDKCK_01035 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
GBLFDKCK_01036 1.3e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GBLFDKCK_01037 0.0 pepN 3.4.11.2 E aminopeptidase
GBLFDKCK_01038 5.4e-113 phoU P Plays a role in the regulation of phosphate uptake
GBLFDKCK_01039 4.6e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBLFDKCK_01040 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBLFDKCK_01041 1.5e-155 pstA P phosphate transport system permease
GBLFDKCK_01042 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
GBLFDKCK_01043 1.2e-155 pstS P phosphate
GBLFDKCK_01044 1.6e-249 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GBLFDKCK_01045 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GBLFDKCK_01046 1e-44 yktA S Belongs to the UPF0223 family
GBLFDKCK_01047 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GBLFDKCK_01048 6.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GBLFDKCK_01049 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBLFDKCK_01050 1.4e-237 XK27_04775 S hemerythrin HHE cation binding domain
GBLFDKCK_01051 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
GBLFDKCK_01052 3.7e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
GBLFDKCK_01053 1.2e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GBLFDKCK_01054 1.2e-137 S haloacid dehalogenase-like hydrolase
GBLFDKCK_01055 3.3e-239 metY 2.5.1.49 E o-acetylhomoserine
GBLFDKCK_01056 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GBLFDKCK_01057 4.3e-242 agcS E (Alanine) symporter
GBLFDKCK_01058 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GBLFDKCK_01059 1.1e-169 bglC K Transcriptional regulator
GBLFDKCK_01060 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
GBLFDKCK_01061 3.2e-81 yecS P ABC transporter (Permease
GBLFDKCK_01062 8.7e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
GBLFDKCK_01063 1.1e-240 nylA 3.5.1.4 J Belongs to the amidase family
GBLFDKCK_01064 2.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GBLFDKCK_01065 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GBLFDKCK_01066 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GBLFDKCK_01067 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GBLFDKCK_01068 2.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
GBLFDKCK_01069 1e-142 S TraX protein
GBLFDKCK_01070 5.1e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GBLFDKCK_01071 3.3e-270 S Psort location CytoplasmicMembrane, score
GBLFDKCK_01072 8.5e-227 dinF V Mate efflux family protein
GBLFDKCK_01073 4.9e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
GBLFDKCK_01074 6e-166 S von Willebrand factor (vWF) type A domain
GBLFDKCK_01075 8.3e-111 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
GBLFDKCK_01076 8.4e-134 2.4.2.3 F Phosphorylase superfamily
GBLFDKCK_01077 1.1e-92 K LysR substrate binding domain
GBLFDKCK_01078 7.5e-125 ltaE 4.1.2.48 E Beta-eliminating lyase
GBLFDKCK_01079 5.1e-105 K Bacterial regulatory proteins, tetR family
GBLFDKCK_01080 8.7e-177 ybhR V ABC-2 family transporter protein
GBLFDKCK_01081 1.9e-127 ybhF_2 V abc transporter atp-binding protein
GBLFDKCK_01082 7.5e-147 G protein with an alpha beta hydrolase fold
GBLFDKCK_01083 3.1e-181 S Hydrolases of the alpha beta superfamily
GBLFDKCK_01084 1.6e-157 K Transcriptional regulator
GBLFDKCK_01085 3.8e-111 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GBLFDKCK_01086 8.1e-32 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
GBLFDKCK_01087 6.7e-201 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GBLFDKCK_01088 3.3e-161 czcD P cation diffusion facilitator family transporter
GBLFDKCK_01089 1.7e-96 K Transcriptional regulator, TetR family
GBLFDKCK_01090 7.2e-67 S Protein of unknown function with HXXEE motif
GBLFDKCK_01091 3.7e-12
GBLFDKCK_01092 2.9e-33 pnuC H nicotinamide mononucleotide transporter
GBLFDKCK_01093 4.4e-112 tnp L DDE domain
GBLFDKCK_01094 3.3e-149 cbiO2 P ABC transporter, ATP-binding protein
GBLFDKCK_01095 4.5e-157 P ATPase activity
GBLFDKCK_01096 1.3e-132 cbiQ P Cobalt transport protein
GBLFDKCK_01097 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
GBLFDKCK_01098 4.4e-141 S Phenazine biosynthesis protein
GBLFDKCK_01099 6.5e-108 magIII L Base excision DNA repair protein, HhH-GPD family
GBLFDKCK_01100 1e-263 proWX P ABC transporter
GBLFDKCK_01101 4.6e-129 proV E abc transporter atp-binding protein
GBLFDKCK_01102 4.5e-169 C alcohol dehydrogenase
GBLFDKCK_01103 1.2e-133 1.6.5.2 GM NmrA-like family
GBLFDKCK_01104 2.3e-67 mgrA K Transcriptional regulator, MarR family
GBLFDKCK_01105 1.1e-31 ymdB S Macro domain protein
GBLFDKCK_01106 2.2e-85 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GBLFDKCK_01107 2.8e-41 C Pyridoxamine 5'-phosphate oxidase
GBLFDKCK_01108 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GBLFDKCK_01109 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GBLFDKCK_01112 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GBLFDKCK_01114 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
GBLFDKCK_01115 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
GBLFDKCK_01116 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
GBLFDKCK_01117 2.3e-181 clcA_2 P Chloride transporter, ClC family
GBLFDKCK_01118 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GBLFDKCK_01119 5.5e-95 S Protein of unknown function (DUF1697)
GBLFDKCK_01120 8e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GBLFDKCK_01121 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GBLFDKCK_01122 2.5e-253 V Glucan-binding protein C
GBLFDKCK_01123 4e-50 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GBLFDKCK_01124 2.7e-224 XK27_05470 E Methionine synthase
GBLFDKCK_01125 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GBLFDKCK_01126 4.7e-236 T PhoQ Sensor
GBLFDKCK_01127 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBLFDKCK_01128 2e-149 S TraX protein
GBLFDKCK_01130 1.3e-51 V ABC-2 family transporter protein
GBLFDKCK_01131 1.2e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
GBLFDKCK_01132 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBLFDKCK_01133 2.5e-155 dprA LU DNA protecting protein DprA
GBLFDKCK_01134 4.4e-161 GK ROK family
GBLFDKCK_01135 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBLFDKCK_01136 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GBLFDKCK_01137 4e-127 K DNA-binding helix-turn-helix protein
GBLFDKCK_01138 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
GBLFDKCK_01139 3.8e-85
GBLFDKCK_01140 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GBLFDKCK_01141 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GBLFDKCK_01142 1e-125 gntR1 K transcriptional
GBLFDKCK_01143 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GBLFDKCK_01144 2.2e-102 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBLFDKCK_01145 3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
GBLFDKCK_01146 2.1e-45
GBLFDKCK_01147 2.6e-51
GBLFDKCK_01148 2.2e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBLFDKCK_01149 4.6e-157 aatB ET ABC transporter substrate-binding protein
GBLFDKCK_01150 4.8e-111 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_01151 1.4e-105 artQ P ABC transporter (Permease
GBLFDKCK_01152 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
GBLFDKCK_01153 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GBLFDKCK_01154 7.6e-166 cpsY K Transcriptional regulator
GBLFDKCK_01155 2e-129 mur1 3.4.17.14, 3.5.1.28 NU muramidase
GBLFDKCK_01156 5.5e-173 yeiH S Membrane
GBLFDKCK_01158 2.6e-09
GBLFDKCK_01159 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
GBLFDKCK_01160 5.8e-149 XK27_10720 D peptidase activity
GBLFDKCK_01161 3.9e-278 pepD E Dipeptidase
GBLFDKCK_01162 5.7e-161 whiA K May be required for sporulation
GBLFDKCK_01163 4.3e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GBLFDKCK_01164 7e-164 rapZ S Displays ATPase and GTPase activities
GBLFDKCK_01165 3.7e-137 yejC S cyclic nucleotide-binding protein
GBLFDKCK_01166 1.3e-207 D nuclear chromosome segregation
GBLFDKCK_01167 5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GBLFDKCK_01168 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GBLFDKCK_01169 1.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
GBLFDKCK_01170 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GBLFDKCK_01171 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
GBLFDKCK_01172 4.3e-201 pmrB EGP Major facilitator Superfamily
GBLFDKCK_01173 4.1e-18
GBLFDKCK_01174 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GBLFDKCK_01175 1.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GBLFDKCK_01176 1.1e-81 ypmB S Protein conserved in bacteria
GBLFDKCK_01177 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GBLFDKCK_01178 2.8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GBLFDKCK_01179 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
GBLFDKCK_01180 1.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
GBLFDKCK_01181 4.1e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GBLFDKCK_01182 2.5e-192 tcsA S membrane
GBLFDKCK_01183 2.5e-68 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GBLFDKCK_01184 3.2e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GBLFDKCK_01185 8.6e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GBLFDKCK_01186 4.6e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
GBLFDKCK_01187 3.6e-171 coaA 2.7.1.33 F Pantothenic acid kinase
GBLFDKCK_01188 1e-29 rpsT J Binds directly to 16S ribosomal RNA
GBLFDKCK_01189 9.5e-240 T PhoQ Sensor
GBLFDKCK_01190 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBLFDKCK_01191 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GBLFDKCK_01192 1.9e-113 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
GBLFDKCK_01193 1.8e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GBLFDKCK_01194 6.4e-94 panT S ECF transporter, substrate-specific component
GBLFDKCK_01195 3.8e-91 panT S Psort location CytoplasmicMembrane, score
GBLFDKCK_01196 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GBLFDKCK_01197 1.6e-165 metF 1.5.1.20 E reductase
GBLFDKCK_01198 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBLFDKCK_01200 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
GBLFDKCK_01201 0.0 3.6.3.8 P cation transport ATPase
GBLFDKCK_01202 7.4e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GBLFDKCK_01203 4.8e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBLFDKCK_01204 1.6e-235 dltB M Membrane protein involved in D-alanine export
GBLFDKCK_01205 2.1e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBLFDKCK_01206 0.0 XK27_10035 V abc transporter atp-binding protein
GBLFDKCK_01207 8e-289 yfiB1 V abc transporter atp-binding protein
GBLFDKCK_01208 1.4e-99 pvaA M lytic transglycosylase activity
GBLFDKCK_01209 1.6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
GBLFDKCK_01210 6.2e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBLFDKCK_01211 4.4e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GBLFDKCK_01212 3.1e-150 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GBLFDKCK_01213 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GBLFDKCK_01214 2.8e-108 tdk 2.7.1.21 F thymidine kinase
GBLFDKCK_01215 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBLFDKCK_01216 4.4e-154 gst O Glutathione S-transferase
GBLFDKCK_01217 2.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
GBLFDKCK_01218 4.6e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GBLFDKCK_01219 4.4e-45 rpmE2 J 50S ribosomal protein L31
GBLFDKCK_01220 1.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
GBLFDKCK_01221 7.6e-164 ypuA S secreted protein
GBLFDKCK_01222 3.9e-74 yaeR E COG0346 Lactoylglutathione lyase and related lyases
GBLFDKCK_01223 3.2e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
GBLFDKCK_01224 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBLFDKCK_01225 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GBLFDKCK_01226 1.4e-256 noxE P NADH oxidase
GBLFDKCK_01227 1.1e-294 yfmM S abc transporter atp-binding protein
GBLFDKCK_01228 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
GBLFDKCK_01229 1.3e-143 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
GBLFDKCK_01230 5e-82 S ECF-type riboflavin transporter, S component
GBLFDKCK_01232 9.4e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBLFDKCK_01233 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
GBLFDKCK_01235 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBLFDKCK_01236 6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBLFDKCK_01237 1.9e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GBLFDKCK_01238 2.9e-22 WQ51_00220 K Helix-turn-helix domain
GBLFDKCK_01239 3.7e-91 S Protein of unknown function (DUF3278)
GBLFDKCK_01240 0.0 smc D Required for chromosome condensation and partitioning
GBLFDKCK_01241 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GBLFDKCK_01242 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBLFDKCK_01243 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GBLFDKCK_01245 3.9e-295 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBLFDKCK_01246 1.1e-89 pat 2.3.1.183 M acetyltransferase
GBLFDKCK_01247 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBLFDKCK_01248 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GBLFDKCK_01249 4.2e-53
GBLFDKCK_01250 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GBLFDKCK_01251 8.2e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
GBLFDKCK_01252 3.2e-86
GBLFDKCK_01253 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
GBLFDKCK_01254 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase
GBLFDKCK_01255 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
GBLFDKCK_01256 2.6e-161 yjlA EG membrane
GBLFDKCK_01257 1.6e-80 3.4.21.89 S RDD family
GBLFDKCK_01258 1.3e-141 K sequence-specific DNA binding
GBLFDKCK_01259 2.1e-146 V ABC transporter, ATP-binding protein
GBLFDKCK_01260 2.8e-94 S ABC-2 family transporter protein
GBLFDKCK_01261 2.1e-139 K sequence-specific DNA binding
GBLFDKCK_01262 4.6e-51 ywrO S general stress protein
GBLFDKCK_01263 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
GBLFDKCK_01264 2e-77 K Acetyltransferase (GNAT) domain
GBLFDKCK_01265 1.6e-140 S ABC-2 family transporter protein
GBLFDKCK_01266 3.2e-139 S ABC transporter (permease)
GBLFDKCK_01267 6.1e-185 S abc transporter atp-binding protein
GBLFDKCK_01270 4.3e-85 yfjR K regulation of single-species biofilm formation
GBLFDKCK_01271 8.8e-125 S Protein of unknown function DUF262
GBLFDKCK_01272 7.2e-209 S Protein of unknown function DUF262
GBLFDKCK_01273 2.6e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBLFDKCK_01274 3.1e-190 desK 2.7.13.3 T Histidine kinase
GBLFDKCK_01275 1.7e-131 yvfS V ABC-2 type transporter
GBLFDKCK_01276 3.9e-159 XK27_09825 V 'abc transporter, ATP-binding protein
GBLFDKCK_01279 1.5e-164 yocS S Transporter
GBLFDKCK_01280 1e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
GBLFDKCK_01281 1.2e-116 yvfS V Transporter
GBLFDKCK_01282 4.1e-156 XK27_09825 V abc transporter atp-binding protein
GBLFDKCK_01283 1.3e-16 liaI KT membrane
GBLFDKCK_01284 9.9e-30 liaI KT membrane
GBLFDKCK_01285 6.1e-93 XK27_05000 S metal cluster binding
GBLFDKCK_01286 0.0 V ABC transporter (permease)
GBLFDKCK_01287 6e-132 macB2 V ABC transporter, ATP-binding protein
GBLFDKCK_01288 2.2e-150 T Histidine kinase
GBLFDKCK_01289 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBLFDKCK_01290 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GBLFDKCK_01291 3.2e-223 pbuX F xanthine permease
GBLFDKCK_01292 7.2e-273 V (ABC) transporter
GBLFDKCK_01293 2.6e-152 K sequence-specific DNA binding
GBLFDKCK_01294 8.7e-243 norM V Multidrug efflux pump
GBLFDKCK_01296 2e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBLFDKCK_01297 8.9e-232 brnQ E Component of the transport system for branched-chain amino acids
GBLFDKCK_01298 3.9e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
GBLFDKCK_01299 8.1e-60 S Protein of unknown function (DUF3290)
GBLFDKCK_01300 9.5e-107 S Protein of unknown function (DUF421)
GBLFDKCK_01301 2.3e-19 csbD K CsbD-like
GBLFDKCK_01302 7.9e-115 S Carbohydrate-binding domain-containing protein Cthe_2159
GBLFDKCK_01303 2e-50 XK27_01300 P Protein conserved in bacteria
GBLFDKCK_01304 4.6e-215 yfnA E amino acid
GBLFDKCK_01305 0.0 S dextransucrase activity
GBLFDKCK_01306 4e-60 M Putative cell wall binding repeat
GBLFDKCK_01308 1.3e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_01309 6e-115 yxeN P ABC transporter, permease protein
GBLFDKCK_01310 9.1e-111 ytmL P ABC transporter (Permease
GBLFDKCK_01311 4e-164 ET ABC transporter substrate-binding protein
GBLFDKCK_01312 1.4e-173 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
GBLFDKCK_01313 9.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GBLFDKCK_01314 1.5e-42 S Sugar efflux transporter for intercellular exchange
GBLFDKCK_01315 5.4e-201 P FtsX-like permease family
GBLFDKCK_01316 1.7e-122 V abc transporter atp-binding protein
GBLFDKCK_01317 1.1e-96 K WHG domain
GBLFDKCK_01318 5.7e-169 ydhF S Aldo keto reductase
GBLFDKCK_01319 1.6e-211 natB CP ABC-type Na efflux pump, permease component
GBLFDKCK_01320 3.3e-161 natA S abc transporter atp-binding protein
GBLFDKCK_01322 3.2e-27 XK27_07105 K transcriptional
GBLFDKCK_01323 3.5e-38
GBLFDKCK_01324 4.3e-109 XK27_02070 S nitroreductase
GBLFDKCK_01325 3.8e-143 1.13.11.2 S glyoxalase
GBLFDKCK_01326 3.7e-73 ywnA K Transcriptional regulator
GBLFDKCK_01327 3.6e-157 E Alpha/beta hydrolase of unknown function (DUF915)
GBLFDKCK_01328 3.6e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GBLFDKCK_01329 4.3e-107 drgA C Nitroreductase family
GBLFDKCK_01330 2.5e-100 yoaK S Protein of unknown function (DUF1275)
GBLFDKCK_01331 1.2e-157 yvgN C reductase
GBLFDKCK_01332 1.4e-209 S Tetratricopeptide repeat
GBLFDKCK_01333 0.0 lacL 3.2.1.23 G -beta-galactosidase
GBLFDKCK_01334 0.0 lacS G transporter
GBLFDKCK_01335 1.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GBLFDKCK_01336 8.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GBLFDKCK_01337 6.1e-285 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GBLFDKCK_01338 1.8e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GBLFDKCK_01339 1.2e-151 galR K Transcriptional regulator
GBLFDKCK_01340 6e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
GBLFDKCK_01341 1.1e-226 vncS 2.7.13.3 T Histidine kinase
GBLFDKCK_01342 5.7e-115 K Response regulator receiver domain protein
GBLFDKCK_01343 1.6e-236 vex3 V Efflux ABC transporter, permease protein
GBLFDKCK_01344 1.9e-107 vex2 V abc transporter atp-binding protein
GBLFDKCK_01345 3.3e-212 vex1 V Efflux ABC transporter, permease protein
GBLFDKCK_01346 2.8e-282 XK27_07020 S Belongs to the UPF0371 family
GBLFDKCK_01348 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
GBLFDKCK_01349 1.6e-177 XK27_10475 S oxidoreductase
GBLFDKCK_01350 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
GBLFDKCK_01351 2.4e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
GBLFDKCK_01352 7.2e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
GBLFDKCK_01353 2.7e-222 thrE K Psort location CytoplasmicMembrane, score
GBLFDKCK_01354 2.7e-133 T Ser Thr phosphatase family protein
GBLFDKCK_01355 5.4e-34 S Immunity protein 41
GBLFDKCK_01356 0.0 pepO 3.4.24.71 O Peptidase family M13
GBLFDKCK_01359 1.6e-15 S integral membrane protein
GBLFDKCK_01360 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
GBLFDKCK_01361 2.6e-108 yhfC S Putative membrane peptidase family (DUF2324)
GBLFDKCK_01362 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_01364 2.7e-240 S dextransucrase activity
GBLFDKCK_01365 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_01366 0.0 S dextransucrase activity
GBLFDKCK_01367 0.0 S dextransucrase activity
GBLFDKCK_01368 0.0 S dextransucrase activity
GBLFDKCK_01369 5.2e-87 M Putative cell wall binding repeat
GBLFDKCK_01370 1.4e-236 tcdB S dextransucrase activity
GBLFDKCK_01371 0.0 S dextransucrase activity
GBLFDKCK_01372 4.6e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GBLFDKCK_01373 2.4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GBLFDKCK_01374 0.0 M Putative cell wall binding repeat
GBLFDKCK_01375 1.1e-302 S dextransucrase activity
GBLFDKCK_01376 0.0 S dextransucrase activity
GBLFDKCK_01377 0.0 S dextransucrase activity
GBLFDKCK_01379 3e-131 XK27_00785 S CAAX protease self-immunity
GBLFDKCK_01380 1.6e-239 EGP Major facilitator Superfamily
GBLFDKCK_01381 1.8e-66 rmaI K Transcriptional regulator, MarR family
GBLFDKCK_01382 6.7e-88 maa 2.3.1.79 GK Maltose O-acetyltransferase
GBLFDKCK_01383 6.1e-137 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
GBLFDKCK_01384 0.0 3.5.1.28 M domain protein
GBLFDKCK_01385 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBLFDKCK_01386 5.1e-119 K Helix-turn-helix domain, rpiR family
GBLFDKCK_01387 1e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
GBLFDKCK_01389 3e-17 sraP UW Tetratricopeptide repeat
GBLFDKCK_01390 2.2e-33 3.4.24.40 U Large extracellular alpha-helical protein
GBLFDKCK_01394 7e-12 S Accessory secretory protein Sec, Asp5
GBLFDKCK_01395 1.1e-12 S Accessory secretory protein Sec Asp4
GBLFDKCK_01396 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GBLFDKCK_01397 1.6e-68 asp3 S Accessory Sec system protein Asp3
GBLFDKCK_01398 1.5e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
GBLFDKCK_01399 5.3e-308 asp1 S Accessory Sec system protein Asp1
GBLFDKCK_01400 2.3e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GBLFDKCK_01401 2.2e-240 M family 8
GBLFDKCK_01402 0.0 M cog cog1442
GBLFDKCK_01403 5.1e-167 cpsJ M Glycosyltransferase group 2 family protein
GBLFDKCK_01404 6.2e-232 M Glycosyltransferase, family 8
GBLFDKCK_01405 9.6e-186 nss M transferase activity, transferring glycosyl groups
GBLFDKCK_01406 1.4e-194 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GBLFDKCK_01407 5.5e-286 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GBLFDKCK_01408 9.9e-238 M Glycosyltransferase, family 8
GBLFDKCK_01409 1e-146 epsH S acetyltransferase'
GBLFDKCK_01410 0.0 M family 8
GBLFDKCK_01411 3.4e-155 cat 2.3.1.28 S acetyltransferase'
GBLFDKCK_01412 0.0 sbcC L ATPase involved in DNA repair
GBLFDKCK_01413 9e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GBLFDKCK_01414 0.0 GM domain, Protein
GBLFDKCK_01415 0.0 zmpB M signal peptide protein, YSIRK family
GBLFDKCK_01416 0.0 M Pilin isopeptide linkage domain protein
GBLFDKCK_01417 6e-34 M Pilin isopeptide linkage domain protein
GBLFDKCK_01418 5e-45 M Pilin isopeptide linkage domain protein
GBLFDKCK_01421 2.2e-194 XK27_10075 S abc transporter atp-binding protein
GBLFDKCK_01422 0.0 V abc transporter atp-binding protein
GBLFDKCK_01423 8.8e-296 V abc transporter atp-binding protein
GBLFDKCK_01424 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
GBLFDKCK_01426 5.9e-288 S Protein of unknown function (DUF3114)
GBLFDKCK_01427 2.9e-99 2.3.1.128 K Acetyltransferase GNAT Family
GBLFDKCK_01428 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GBLFDKCK_01429 3.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
GBLFDKCK_01430 2.8e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
GBLFDKCK_01431 3.1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBLFDKCK_01432 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GBLFDKCK_01433 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GBLFDKCK_01434 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GBLFDKCK_01435 1.3e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GBLFDKCK_01436 5.5e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GBLFDKCK_01437 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GBLFDKCK_01440 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBLFDKCK_01441 5.7e-170 vraS 2.7.13.3 T Histidine kinase
GBLFDKCK_01442 3.3e-116 yvqF S Membrane
GBLFDKCK_01444 9e-104 kcsA P Ion transport protein
GBLFDKCK_01445 1.4e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
GBLFDKCK_01446 4.8e-137 stp 3.1.3.16 T phosphatase
GBLFDKCK_01447 1e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBLFDKCK_01448 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBLFDKCK_01449 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBLFDKCK_01450 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
GBLFDKCK_01451 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GBLFDKCK_01452 3.8e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GBLFDKCK_01453 1.2e-146 XK27_02985 S overlaps another CDS with the same product name
GBLFDKCK_01454 3.1e-147 supH S overlaps another CDS with the same product name
GBLFDKCK_01455 6.1e-61 yvoA_1 K Transcriptional
GBLFDKCK_01456 4e-122 skfE V abc transporter atp-binding protein
GBLFDKCK_01457 1.3e-126 V Psort location CytoplasmicMembrane, score
GBLFDKCK_01458 1e-170 oppF P Belongs to the ABC transporter superfamily
GBLFDKCK_01459 2.3e-201 oppD P Belongs to the ABC transporter superfamily
GBLFDKCK_01460 1.4e-167 amiD P ABC transporter (Permease
GBLFDKCK_01461 3.5e-277 amiC P ABC transporter (Permease
GBLFDKCK_01462 7.3e-307 amiA E ABC transporter, substrate-binding protein, family 5
GBLFDKCK_01463 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GBLFDKCK_01464 2.4e-173 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GBLFDKCK_01465 4.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GBLFDKCK_01466 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBLFDKCK_01467 6.7e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
GBLFDKCK_01468 7.1e-101 yjbK S Adenylate cyclase
GBLFDKCK_01469 1.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBLFDKCK_01470 6.9e-201 iscS 2.8.1.7 E Cysteine desulfurase
GBLFDKCK_01471 4.1e-59 XK27_04120 S Putative amino acid metabolism
GBLFDKCK_01472 6.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GBLFDKCK_01473 1.8e-127 puuD T peptidase C26
GBLFDKCK_01474 1.8e-114 radC E Belongs to the UPF0758 family
GBLFDKCK_01475 1.5e-305 rgpF M Rhamnan synthesis protein F
GBLFDKCK_01476 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GBLFDKCK_01477 6.8e-142 rgpC GM Transport permease protein
GBLFDKCK_01478 1.2e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
GBLFDKCK_01479 5.4e-225 rgpA GT4 M Domain of unknown function (DUF1972)
GBLFDKCK_01480 2e-45 S Glucosyl transferase GtrII
GBLFDKCK_01481 3.7e-103 S Glucosyl transferase GtrII
GBLFDKCK_01482 6.1e-76 S Glucosyl transferase GtrII
GBLFDKCK_01483 4.4e-233 GT4 M transferase activity, transferring glycosyl groups
GBLFDKCK_01484 1.7e-221 M Psort location CytoplasmicMembrane, score
GBLFDKCK_01485 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
GBLFDKCK_01486 4.1e-117
GBLFDKCK_01487 1.5e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
GBLFDKCK_01488 1.9e-43 S Uncharacterized conserved protein (DUF2304)
GBLFDKCK_01489 7e-127 arnC M group 2 family protein
GBLFDKCK_01490 7.8e-177 cpsIaJ S Glycosyltransferase like family 2
GBLFDKCK_01491 6.3e-155 M Glycosyltransferase, group 2 family protein
GBLFDKCK_01492 1.3e-227 amrA S membrane protein involved in the export of O-antigen and teichoic acid
GBLFDKCK_01493 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GBLFDKCK_01494 4.3e-267 S Glucosyl transferase GtrII
GBLFDKCK_01495 3.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GBLFDKCK_01496 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
GBLFDKCK_01497 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GBLFDKCK_01498 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GBLFDKCK_01499 1.9e-33 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GBLFDKCK_01500 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GBLFDKCK_01501 5.5e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
GBLFDKCK_01502 1.1e-211 arcT 2.6.1.1 E Aminotransferase
GBLFDKCK_01503 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
GBLFDKCK_01504 3.5e-138 ET ABC transporter
GBLFDKCK_01505 2.2e-84 mutT 3.6.1.55 F Nudix family
GBLFDKCK_01507 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GBLFDKCK_01509 3.4e-169 S CAAX amino terminal protease family protein
GBLFDKCK_01510 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
GBLFDKCK_01511 5.7e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_01512 1.7e-17 XK27_00735
GBLFDKCK_01513 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GBLFDKCK_01515 3.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBLFDKCK_01516 5.7e-10 O ADP-ribosylglycohydrolase
GBLFDKCK_01517 4.3e-62 paaI Q protein possibly involved in aromatic compounds catabolism
GBLFDKCK_01518 2.7e-61 ycaO O OsmC-like protein
GBLFDKCK_01520 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
GBLFDKCK_01521 2.5e-07 N PFAM Uncharacterised protein family UPF0150
GBLFDKCK_01522 3.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
GBLFDKCK_01523 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GBLFDKCK_01524 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBLFDKCK_01525 5.5e-98 3.1.3.18 S IA, variant 1
GBLFDKCK_01526 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GBLFDKCK_01527 3.5e-56 lrgA S Effector of murein hydrolase LrgA
GBLFDKCK_01528 2.7e-296
GBLFDKCK_01529 3.4e-217 dcm 2.1.1.37 H cytosine-specific methyltransferase
GBLFDKCK_01530 1.6e-52 E amidohydrolase
GBLFDKCK_01531 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GBLFDKCK_01532 5.7e-172 S Helix-hairpin-helix DNA-binding motif class 1
GBLFDKCK_01533 5e-107 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBLFDKCK_01534 1.3e-107 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBLFDKCK_01535 3e-14 coiA 3.6.4.12 S Competence protein
GBLFDKCK_01536 7.5e-16 T peptidase
GBLFDKCK_01537 2e-147 rarD S Transporter
GBLFDKCK_01538 4.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GBLFDKCK_01539 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GBLFDKCK_01540 6.7e-135 yxkH G deacetylase
GBLFDKCK_01541 1.2e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GBLFDKCK_01542 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GBLFDKCK_01543 5.6e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBLFDKCK_01544 1.1e-186 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GBLFDKCK_01545 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
GBLFDKCK_01546 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GBLFDKCK_01547 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
GBLFDKCK_01549 1.3e-230 2.7.13.3 T GHKL domain
GBLFDKCK_01550 5.6e-135 agrA KT response regulator
GBLFDKCK_01551 3.1e-07
GBLFDKCK_01552 1.6e-187 femA 2.3.2.10, 2.3.2.16 V FemAB family
GBLFDKCK_01554 4.9e-60 arsC 1.20.4.1 P Belongs to the ArsC family
GBLFDKCK_01555 5.4e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
GBLFDKCK_01556 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBLFDKCK_01557 5.1e-104 wecD M Acetyltransferase (GNAT) domain
GBLFDKCK_01558 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GBLFDKCK_01559 8.3e-157 GK ROK family
GBLFDKCK_01560 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
GBLFDKCK_01561 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
GBLFDKCK_01562 1.8e-203 potD P spermidine putrescine ABC transporter
GBLFDKCK_01563 4.4e-130 potC P ABC-type spermidine putrescine transport system, permease component II
GBLFDKCK_01564 1.5e-138 potB P ABC-type spermidine putrescine transport system, permease component I
GBLFDKCK_01565 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GBLFDKCK_01566 2.8e-168 murB 1.3.1.98 M cell wall formation
GBLFDKCK_01567 4.1e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GBLFDKCK_01568 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GBLFDKCK_01569 6.4e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GBLFDKCK_01570 1.7e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GBLFDKCK_01571 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
GBLFDKCK_01572 0.0 ydaO E amino acid
GBLFDKCK_01573 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GBLFDKCK_01574 2.4e-37 ylqC L Belongs to the UPF0109 family
GBLFDKCK_01575 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GBLFDKCK_01577 7.8e-198 2.7.13.3 T GHKL domain
GBLFDKCK_01578 2.7e-129 agrA KT phosphorelay signal transduction system
GBLFDKCK_01579 2.8e-190 O protein import
GBLFDKCK_01580 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
GBLFDKCK_01581 2.2e-17 yhaI L Membrane
GBLFDKCK_01582 5.1e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBLFDKCK_01584 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
GBLFDKCK_01585 5.8e-72 S QueT transporter
GBLFDKCK_01587 5e-171 yfjR K regulation of single-species biofilm formation
GBLFDKCK_01588 2e-183 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GBLFDKCK_01589 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBLFDKCK_01590 2.8e-85 ccl S cog cog4708
GBLFDKCK_01591 3.7e-163 rbn E Belongs to the UPF0761 family
GBLFDKCK_01592 3.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GBLFDKCK_01593 3e-232 ytoI K transcriptional regulator containing CBS domains
GBLFDKCK_01594 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
GBLFDKCK_01595 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBLFDKCK_01596 0.0 comEC S Competence protein ComEC
GBLFDKCK_01597 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GBLFDKCK_01598 1.7e-142 plsC 2.3.1.51 I Acyltransferase
GBLFDKCK_01599 4.5e-137 nodB3 G deacetylase
GBLFDKCK_01600 3.3e-138 yabB 2.1.1.223 L Methyltransferase
GBLFDKCK_01601 1.1e-40 yazA L endonuclease containing a URI domain
GBLFDKCK_01602 4.6e-243 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GBLFDKCK_01603 8.7e-154 corA P CorA-like protein
GBLFDKCK_01604 3.3e-62 yjqA S Bacterial PH domain
GBLFDKCK_01605 1e-99 thiT S Thiamine transporter
GBLFDKCK_01606 8.9e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GBLFDKCK_01607 1e-114 ywaF S Integral membrane protein (intg_mem_TP0381)
GBLFDKCK_01608 2.1e-252 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GBLFDKCK_01611 3.3e-155 cjaA ET ABC transporter substrate-binding protein
GBLFDKCK_01612 5.8e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_01613 3e-106 P ABC transporter (Permease
GBLFDKCK_01614 3e-114 papP P ABC transporter (Permease
GBLFDKCK_01615 5.4e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GBLFDKCK_01618 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
GBLFDKCK_01619 0.0 copA 3.6.3.54 P P-type ATPase
GBLFDKCK_01620 1.8e-72 copY K negative regulation of transcription, DNA-templated
GBLFDKCK_01621 1.8e-175 EGP Major facilitator Superfamily
GBLFDKCK_01623 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GBLFDKCK_01624 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GBLFDKCK_01625 4.8e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
GBLFDKCK_01626 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GBLFDKCK_01627 4.3e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GBLFDKCK_01628 4e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
GBLFDKCK_01629 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBLFDKCK_01630 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
GBLFDKCK_01631 3.5e-120 yujD V lipoprotein transporter activity
GBLFDKCK_01632 0.0 S bacteriocin-associated integral membrane protein
GBLFDKCK_01633 2.1e-19 S Bacteriocin (Lactococcin_972)
GBLFDKCK_01634 1.2e-59
GBLFDKCK_01635 0.0 ctpE P E1-E2 ATPase
GBLFDKCK_01636 1.1e-44
GBLFDKCK_01637 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBLFDKCK_01639 1.5e-124 V abc transporter atp-binding protein
GBLFDKCK_01640 0.0 V ABC transporter (Permease
GBLFDKCK_01641 7.8e-121 K transcriptional regulator, MerR family
GBLFDKCK_01642 3.5e-103 dnaQ 2.7.7.7 L DNA polymerase III
GBLFDKCK_01643 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
GBLFDKCK_01644 2.1e-63 XK27_02560 S cog cog2151
GBLFDKCK_01645 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GBLFDKCK_01646 4.7e-224 ytfP S Flavoprotein
GBLFDKCK_01648 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GBLFDKCK_01649 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
GBLFDKCK_01650 9.3e-176 ecsB U Bacterial ABC transporter protein EcsB
GBLFDKCK_01651 1.9e-130 ecsA V abc transporter atp-binding protein
GBLFDKCK_01652 2.3e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GBLFDKCK_01653 4.1e-07
GBLFDKCK_01655 1.6e-103
GBLFDKCK_01657 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
GBLFDKCK_01659 7.9e-44 yoeB S Addiction module toxin, Txe YoeB family
GBLFDKCK_01660 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GBLFDKCK_01661 2.2e-196 ylbM S Belongs to the UPF0348 family
GBLFDKCK_01662 1.3e-139 yqeM Q Methyltransferase domain protein
GBLFDKCK_01663 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GBLFDKCK_01664 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GBLFDKCK_01665 4.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GBLFDKCK_01666 7.7e-49 yhbY J RNA-binding protein
GBLFDKCK_01667 4.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GBLFDKCK_01668 2e-97 yqeG S hydrolase of the HAD superfamily
GBLFDKCK_01669 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GBLFDKCK_01670 1.6e-64
GBLFDKCK_01671 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBLFDKCK_01672 2.2e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GBLFDKCK_01673 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBLFDKCK_01674 7.6e-58 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
GBLFDKCK_01675 1e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GBLFDKCK_01676 6.8e-101 pncA Q isochorismatase
GBLFDKCK_01677 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GBLFDKCK_01678 3.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
GBLFDKCK_01679 9e-75 XK27_03180 T universal stress protein
GBLFDKCK_01681 3.9e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBLFDKCK_01682 5.2e-08 MU outer membrane autotransporter barrel domain protein
GBLFDKCK_01683 1.5e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
GBLFDKCK_01684 4.1e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
GBLFDKCK_01685 0.0 yjcE P NhaP-type Na H and K H antiporters
GBLFDKCK_01687 1e-96 ytqB 2.1.1.176 J (SAM)-dependent
GBLFDKCK_01688 8.4e-184 yhcC S radical SAM protein
GBLFDKCK_01689 4.2e-187 ylbL T Belongs to the peptidase S16 family
GBLFDKCK_01690 1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GBLFDKCK_01691 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
GBLFDKCK_01692 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GBLFDKCK_01693 5e-10 S Protein of unknown function (DUF4059)
GBLFDKCK_01694 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
GBLFDKCK_01695 6.1e-163 yxeN P ABC transporter (Permease
GBLFDKCK_01696 1.9e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBLFDKCK_01697 3.3e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBLFDKCK_01698 3.6e-35
GBLFDKCK_01699 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBLFDKCK_01700 0.0 pflB 2.3.1.54 C formate acetyltransferase'
GBLFDKCK_01702 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
GBLFDKCK_01703 1.6e-148 cah 4.2.1.1 P carbonic anhydrase
GBLFDKCK_01704 2.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBLFDKCK_01706 1.6e-179 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
GBLFDKCK_01707 3.2e-141 cppA E CppA N-terminal
GBLFDKCK_01708 4.5e-107 V CAAX protease self-immunity
GBLFDKCK_01709 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GBLFDKCK_01710 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GBLFDKCK_01711 5.4e-44 spiA K sequence-specific DNA binding
GBLFDKCK_01712 4.9e-136 blpT
GBLFDKCK_01718 1.6e-129 agrA KT LytTr DNA-binding domain
GBLFDKCK_01719 1.2e-215 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GBLFDKCK_01721 2e-105 mesE M Transport protein ComB
GBLFDKCK_01722 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GBLFDKCK_01728 0.0 mdlB V abc transporter atp-binding protein
GBLFDKCK_01729 0.0 mdlA V abc transporter atp-binding protein
GBLFDKCK_01731 6.1e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
GBLFDKCK_01732 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GBLFDKCK_01733 1.7e-62 yutD J protein conserved in bacteria
GBLFDKCK_01734 1.3e-260 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GBLFDKCK_01737 9.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GBLFDKCK_01738 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GBLFDKCK_01739 0.0 ftsI 3.4.16.4 M penicillin-binding protein
GBLFDKCK_01740 4e-45 ftsL D cell division protein FtsL
GBLFDKCK_01741 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GBLFDKCK_01743 5e-69 yhaI J Protein of unknown function (DUF805)
GBLFDKCK_01744 2.1e-64 yhaI S Protein of unknown function (DUF805)
GBLFDKCK_01745 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GBLFDKCK_01746 8.8e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBLFDKCK_01747 1.5e-273 XK27_00765
GBLFDKCK_01748 1.3e-131 ecsA_2 V abc transporter atp-binding protein
GBLFDKCK_01749 1.4e-125 S Protein of unknown function (DUF554)
GBLFDKCK_01750 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GBLFDKCK_01751 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GBLFDKCK_01752 4.3e-245 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01753 2.7e-233 dcuS 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01754 8.9e-14
GBLFDKCK_01757 6.4e-145 V Psort location CytoplasmicMembrane, score
GBLFDKCK_01759 9.2e-300 O MreB/Mbl protein
GBLFDKCK_01760 6.3e-112 liaI S membrane
GBLFDKCK_01761 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
GBLFDKCK_01762 0.0 KT response to antibiotic
GBLFDKCK_01763 3.4e-129 yebC M Membrane
GBLFDKCK_01764 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
GBLFDKCK_01765 2e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GBLFDKCK_01767 2.9e-31 yozG K Transcriptional regulator
GBLFDKCK_01771 6.6e-123
GBLFDKCK_01772 4.7e-160 V ABC transporter
GBLFDKCK_01773 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GBLFDKCK_01774 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBLFDKCK_01775 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GBLFDKCK_01776 2.2e-204 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBLFDKCK_01777 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBLFDKCK_01778 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GBLFDKCK_01780 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
GBLFDKCK_01781 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
GBLFDKCK_01782 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBLFDKCK_01783 1.3e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GBLFDKCK_01784 3.7e-179 scrR K Transcriptional regulator
GBLFDKCK_01785 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBLFDKCK_01786 1.8e-60 yqhY S protein conserved in bacteria
GBLFDKCK_01787 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBLFDKCK_01788 1.3e-84 comEB 3.5.4.12 F ComE operon protein 2
GBLFDKCK_01789 3.1e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
GBLFDKCK_01790 4.7e-32 blpT
GBLFDKCK_01794 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GBLFDKCK_01795 8.4e-168 corA P COG0598 Mg2 and Co2 transporters
GBLFDKCK_01796 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
GBLFDKCK_01798 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GBLFDKCK_01799 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GBLFDKCK_01800 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
GBLFDKCK_01801 4.1e-128 S Uncharacterised protein family (UPF0236)
GBLFDKCK_01803 4e-67 tnpR L Resolvase, N terminal domain
GBLFDKCK_01805 8.6e-176 U relaxase
GBLFDKCK_01806 2.1e-16 S Bacterial mobilisation protein (MobC)
GBLFDKCK_01808 2.1e-274 1.11.1.5, 4.2.2.2 L Psort location Cytoplasmic, score
GBLFDKCK_01809 5.5e-213 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBLFDKCK_01810 3.4e-25 radC 3.6.4.12 L Toprim-like
GBLFDKCK_01812 2.1e-229 U TraM recognition site of TraD and TraG
GBLFDKCK_01814 6.3e-19
GBLFDKCK_01817 7e-39
GBLFDKCK_01818 3.4e-225 M CHAP domain protein
GBLFDKCK_01819 0.0 U Domain of unknown function DUF87
GBLFDKCK_01820 2.7e-16 S PrgI family protein
GBLFDKCK_01821 5.1e-67
GBLFDKCK_01824 1.1e-09
GBLFDKCK_01827 9.7e-12
GBLFDKCK_01829 3.5e-75 repA S Replication initiator protein A
GBLFDKCK_01830 3.6e-10
GBLFDKCK_01831 1.5e-42 XK27_05745
GBLFDKCK_01832 6.1e-229 mutY L A G-specific adenine glycosylase
GBLFDKCK_01834 4.8e-07
GBLFDKCK_01835 1.3e-37
GBLFDKCK_01837 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBLFDKCK_01838 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GBLFDKCK_01839 1.1e-92 cvpA S toxin biosynthetic process
GBLFDKCK_01840 2.7e-14 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GBLFDKCK_01841 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBLFDKCK_01842 1.1e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GBLFDKCK_01843 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GBLFDKCK_01844 3.7e-46 azlD S branched-chain amino acid
GBLFDKCK_01845 3e-114 azlC E AzlC protein
GBLFDKCK_01846 3.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GBLFDKCK_01847 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GBLFDKCK_01848 3.5e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
GBLFDKCK_01849 5.7e-33 ykzG S Belongs to the UPF0356 family
GBLFDKCK_01850 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBLFDKCK_01851 6.3e-84 pscB M CHAP domain protein
GBLFDKCK_01852 7.7e-14 pscB M CHAP domain protein
GBLFDKCK_01853 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
GBLFDKCK_01854 2.5e-62 glnR K Transcriptional regulator
GBLFDKCK_01855 1.5e-86 S Fusaric acid resistance protein-like
GBLFDKCK_01856 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GBLFDKCK_01857 2.5e-13
GBLFDKCK_01858 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GBLFDKCK_01859 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GBLFDKCK_01860 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GBLFDKCK_01861 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GBLFDKCK_01862 1.2e-141 purR 2.4.2.7 F operon repressor
GBLFDKCK_01863 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
GBLFDKCK_01864 1.4e-170 rmuC S RmuC domain protein
GBLFDKCK_01865 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
GBLFDKCK_01866 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GBLFDKCK_01867 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GBLFDKCK_01869 4.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GBLFDKCK_01870 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GBLFDKCK_01871 6.6e-145 tatD L Hydrolase, tatd
GBLFDKCK_01872 7.2e-74 yccU S CoA-binding protein
GBLFDKCK_01873 6.3e-51 trxA O Belongs to the thioredoxin family
GBLFDKCK_01874 6e-143 S Macro domain protein
GBLFDKCK_01875 8.2e-59 L thioesterase
GBLFDKCK_01876 4.6e-52 bta 1.8.1.8 CO cell redox homeostasis
GBLFDKCK_01879 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GBLFDKCK_01880 3.4e-14 rpmH J Ribosomal protein L34
GBLFDKCK_01881 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GBLFDKCK_01882 2e-106 K Transcriptional regulator
GBLFDKCK_01883 1.5e-181 jag S RNA-binding protein
GBLFDKCK_01884 8.2e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBLFDKCK_01885 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GBLFDKCK_01886 1.3e-268 argH 4.3.2.1 E Argininosuccinate lyase
GBLFDKCK_01887 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GBLFDKCK_01888 2.8e-134 fasA KT Response regulator of the LytR AlgR family
GBLFDKCK_01889 1.3e-238 fasC 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01890 4.3e-207 hpk9 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01891 1.2e-150 hpk9 2.7.13.3 T protein histidine kinase activity
GBLFDKCK_01892 1.4e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GBLFDKCK_01893 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBLFDKCK_01894 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GBLFDKCK_01895 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GBLFDKCK_01896 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBLFDKCK_01897 1.2e-50 S Protein of unknown function (DUF3397)
GBLFDKCK_01898 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GBLFDKCK_01899 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
GBLFDKCK_01900 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GBLFDKCK_01901 6e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GBLFDKCK_01902 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GBLFDKCK_01903 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
GBLFDKCK_01904 6e-230 XK27_09615 C reductase
GBLFDKCK_01905 2.1e-140 fnt P Formate nitrite transporter
GBLFDKCK_01906 1.6e-94 XK27_08585 S Psort location CytoplasmicMembrane, score
GBLFDKCK_01907 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GBLFDKCK_01908 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GBLFDKCK_01909 1.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GBLFDKCK_01910 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBLFDKCK_01911 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GBLFDKCK_01912 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GBLFDKCK_01913 1.8e-141 S HAD hydrolase, family IA, variant
GBLFDKCK_01914 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
GBLFDKCK_01918 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GBLFDKCK_01919 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GBLFDKCK_01920 4.7e-120 S CAAX protease self-immunity
GBLFDKCK_01921 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBLFDKCK_01922 7.6e-09 S NTF2 fold immunity protein
GBLFDKCK_01923 9.4e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GBLFDKCK_01924 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
GBLFDKCK_01925 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GBLFDKCK_01926 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBLFDKCK_01927 1.8e-100 S CAAX amino terminal protease family protein
GBLFDKCK_01929 7.3e-110 V CAAX protease self-immunity
GBLFDKCK_01930 8.8e-27 lanR K sequence-specific DNA binding
GBLFDKCK_01931 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GBLFDKCK_01932 3.2e-175 ytxK 2.1.1.72 L DNA methylase
GBLFDKCK_01933 2e-12 comGF U Putative Competence protein ComGF
GBLFDKCK_01934 4.5e-71 comGF U Competence protein ComGF
GBLFDKCK_01935 3.1e-15 NU Type II secretory pathway pseudopilin
GBLFDKCK_01936 6.4e-70 cglD NU Competence protein
GBLFDKCK_01937 2.2e-43 comGC U Required for transformation and DNA binding
GBLFDKCK_01938 4.1e-142 cglB U protein transport across the cell outer membrane
GBLFDKCK_01939 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GBLFDKCK_01940 2.9e-68 S cog cog4699
GBLFDKCK_01941 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBLFDKCK_01942 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBLFDKCK_01943 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBLFDKCK_01944 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBLFDKCK_01945 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GBLFDKCK_01946 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
GBLFDKCK_01947 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
GBLFDKCK_01948 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GBLFDKCK_01949 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
GBLFDKCK_01950 1.4e-57 asp S cog cog1302
GBLFDKCK_01951 7.1e-226 norN V Mate efflux family protein
GBLFDKCK_01952 1.3e-276 thrC 4.2.3.1 E Threonine synthase
GBLFDKCK_01955 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GBLFDKCK_01956 0.0 pepO 3.4.24.71 O Peptidase family M13
GBLFDKCK_01957 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GBLFDKCK_01958 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBLFDKCK_01959 5.1e-125 treR K trehalose operon
GBLFDKCK_01960 6.3e-94 ywlG S Belongs to the UPF0340 family
GBLFDKCK_01963 4.9e-220 3.6.4.12 K Divergent AAA domain protein
GBLFDKCK_01964 1.4e-127 2.1.1.113 L Belongs to the N(4) N(6)-methyltransferase family
GBLFDKCK_01965 2.5e-66 avaIR 3.1.21.4 J PFAM Restriction endonuclease BsobI
GBLFDKCK_01966 6.7e-37 K Putative DNA-binding domain
GBLFDKCK_01967 6.9e-23
GBLFDKCK_01968 9.5e-108 K Peptidase S24-like protein
GBLFDKCK_01969 1.3e-127 E IrrE N-terminal-like domain
GBLFDKCK_01971 1.2e-47 K Helix-turn-helix XRE-family like proteins
GBLFDKCK_01973 1.3e-42
GBLFDKCK_01974 7.7e-74
GBLFDKCK_01975 3.7e-275 ydcQ D Ftsk spoiiie family protein
GBLFDKCK_01976 5.6e-81 2.3.1.128 J Acetyltransferase GNAT Family
GBLFDKCK_01977 3.3e-13 K Transcriptional
GBLFDKCK_01979 1.2e-87 L Replication initiation factor
GBLFDKCK_01980 4.5e-10 S Domain of unknown function (DUF3173)
GBLFDKCK_01981 2.3e-212 L Belongs to the 'phage' integrase family
GBLFDKCK_01982 3e-221 K Replication initiation factor
GBLFDKCK_01983 1.5e-33
GBLFDKCK_01984 4.3e-87
GBLFDKCK_01985 1.2e-161 S Conjugative transposon protein TcpC
GBLFDKCK_01986 3.2e-33
GBLFDKCK_01987 2.7e-70 S TcpE family
GBLFDKCK_01988 0.0 yddE S AAA-like domain
GBLFDKCK_01989 7.9e-157
GBLFDKCK_01990 5.3e-94
GBLFDKCK_01991 6.7e-31
GBLFDKCK_01992 8.1e-170 isp2 S pathogenesis
GBLFDKCK_01994 1.5e-15
GBLFDKCK_01995 9.1e-200 L DNA integration
GBLFDKCK_01996 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
GBLFDKCK_01998 3.8e-182 L the current gene model (or a revised gene model) may contain a
GBLFDKCK_01999 2.7e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
GBLFDKCK_02000 4.4e-62 rplQ J ribosomal protein l17
GBLFDKCK_02001 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBLFDKCK_02002 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GBLFDKCK_02003 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBLFDKCK_02004 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GBLFDKCK_02005 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GBLFDKCK_02006 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GBLFDKCK_02007 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GBLFDKCK_02008 1.7e-57 rplO J binds to the 23S rRNA
GBLFDKCK_02009 1.9e-23 rpmD J ribosomal protein l30
GBLFDKCK_02010 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GBLFDKCK_02011 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GBLFDKCK_02012 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GBLFDKCK_02013 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GBLFDKCK_02014 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GBLFDKCK_02015 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GBLFDKCK_02016 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GBLFDKCK_02017 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GBLFDKCK_02018 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GBLFDKCK_02019 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
GBLFDKCK_02020 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GBLFDKCK_02021 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GBLFDKCK_02022 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GBLFDKCK_02023 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GBLFDKCK_02024 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GBLFDKCK_02025 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GBLFDKCK_02026 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
GBLFDKCK_02027 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GBLFDKCK_02028 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GBLFDKCK_02029 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GBLFDKCK_02030 0.0 XK27_09800 I Acyltransferase
GBLFDKCK_02031 9.7e-36 XK27_09805 S MORN repeat protein
GBLFDKCK_02032 1.7e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBLFDKCK_02033 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBLFDKCK_02034 5.7e-94 adk 2.7.4.3 F topology modulation protein
GBLFDKCK_02036 3.2e-173 yeiH S membrane
GBLFDKCK_02037 3.8e-90 K Cro/C1-type HTH DNA-binding domain
GBLFDKCK_02038 3.8e-155 L Replication initiation factor
GBLFDKCK_02039 1.9e-18 S Domain of unknown function (DUF3173)
GBLFDKCK_02040 1e-212 int L Belongs to the 'phage' integrase family
GBLFDKCK_02042 4.8e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
GBLFDKCK_02043 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GBLFDKCK_02044 6.3e-44 yrzL S Belongs to the UPF0297 family
GBLFDKCK_02045 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBLFDKCK_02046 3.2e-44 yrzB S Belongs to the UPF0473 family
GBLFDKCK_02047 7e-295 ccs S the current gene model (or a revised gene model) may contain a frame shift
GBLFDKCK_02048 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GBLFDKCK_02049 7.5e-14
GBLFDKCK_02050 5.4e-89 XK27_10930 K acetyltransferase
GBLFDKCK_02051 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBLFDKCK_02052 6.8e-125 yaaA S Belongs to the UPF0246 family
GBLFDKCK_02053 6.4e-168 XK27_01785 S cog cog1284
GBLFDKCK_02054 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GBLFDKCK_02056 7e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
GBLFDKCK_02057 2.7e-239 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBLFDKCK_02058 1.9e-219 metE 2.1.1.14 E Methionine synthase
GBLFDKCK_02059 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GBLFDKCK_02060 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GBLFDKCK_02061 2.5e-07
GBLFDKCK_02064 1.5e-117 nudL L hydrolase
GBLFDKCK_02065 6.3e-54 K transcriptional regulator, PadR family
GBLFDKCK_02066 2e-63 XK27_06920 S Protein of unknown function (DUF1700)
GBLFDKCK_02067 3.6e-109 S Putative adhesin
GBLFDKCK_02068 8.1e-159 XK27_06930 V domain protein
GBLFDKCK_02069 9.9e-97 XK27_06935 K transcriptional regulator
GBLFDKCK_02070 4.1e-54 ypaA M Membrane
GBLFDKCK_02071 1.9e-10
GBLFDKCK_02072 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GBLFDKCK_02073 1.8e-47 veg S Biofilm formation stimulator VEG
GBLFDKCK_02074 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GBLFDKCK_02075 2.2e-73 rplI J binds to the 23S rRNA
GBLFDKCK_02076 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GBLFDKCK_02077 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GBLFDKCK_02078 1.3e-78 F NUDIX domain
GBLFDKCK_02079 2.4e-99 yvbG U UPF0056 membrane protein
GBLFDKCK_02080 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GBLFDKCK_02081 0.0 S Bacterial membrane protein, YfhO
GBLFDKCK_02082 5.8e-73 isaA GH23 M Immunodominant staphylococcal antigen A
GBLFDKCK_02083 5.7e-74 lytE M LysM domain protein
GBLFDKCK_02084 6.3e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBLFDKCK_02085 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBLFDKCK_02086 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBLFDKCK_02087 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBLFDKCK_02088 3.3e-134 S sequence-specific DNA binding
GBLFDKCK_02089 2.8e-243 ymfH S Peptidase M16
GBLFDKCK_02090 4.8e-235 ymfF S Peptidase M16
GBLFDKCK_02091 8.9e-60 yaaA S S4 domain protein YaaA
GBLFDKCK_02092 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBLFDKCK_02093 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GBLFDKCK_02094 2.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GBLFDKCK_02095 2.2e-154 yvjA S membrane
GBLFDKCK_02096 5.1e-306 ybiT S abc transporter atp-binding protein
GBLFDKCK_02097 0.0 XK27_10405 S Bacterial membrane protein YfhO
GBLFDKCK_02101 6.2e-120 yoaK S Protein of unknown function (DUF1275)
GBLFDKCK_02102 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GBLFDKCK_02103 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GBLFDKCK_02104 2.6e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)