ORF_ID e_value Gene_name EC_number CAZy COGs Description
HNLDEPFJ_00001 1.4e-299 dnaK O Heat shock 70 kDa protein
HNLDEPFJ_00002 7e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNLDEPFJ_00003 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNLDEPFJ_00004 1.4e-99 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HNLDEPFJ_00005 3.1e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HNLDEPFJ_00006 2.8e-131 ais G Phosphoglycerate mutase
HNLDEPFJ_00007 6.6e-243 XK27_08635 S UPF0210 protein
HNLDEPFJ_00008 6.1e-39 gcvR T UPF0237 protein
HNLDEPFJ_00009 2.1e-179 capA M Bacterial capsule synthesis protein
HNLDEPFJ_00010 1.7e-139 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNLDEPFJ_00011 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNLDEPFJ_00012 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNLDEPFJ_00013 5.8e-158 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNLDEPFJ_00014 1.1e-29 yyzM S Protein conserved in bacteria
HNLDEPFJ_00015 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNLDEPFJ_00016 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNLDEPFJ_00017 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNLDEPFJ_00018 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HNLDEPFJ_00019 3e-60 divIC D Septum formation initiator
HNLDEPFJ_00021 1.2e-18 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HNLDEPFJ_00022 7.1e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HNLDEPFJ_00023 1.5e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNLDEPFJ_00025 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNLDEPFJ_00027 8.4e-70 K LytTr DNA-binding domain
HNLDEPFJ_00028 1e-78 S Protein of unknown function (DUF3021)
HNLDEPFJ_00029 1.4e-234 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNLDEPFJ_00030 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HNLDEPFJ_00031 6.1e-99 metI P ABC transporter (Permease
HNLDEPFJ_00032 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNLDEPFJ_00033 5.9e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HNLDEPFJ_00034 1.1e-158 metQ M Belongs to the NlpA lipoprotein family
HNLDEPFJ_00035 9.3e-92 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNLDEPFJ_00036 7.3e-50 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNLDEPFJ_00037 9.1e-234 sufD O assembly protein SufD
HNLDEPFJ_00038 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HNLDEPFJ_00039 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
HNLDEPFJ_00040 1.2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HNLDEPFJ_00041 6.3e-18 S Protein of unknown function (DUF3021)
HNLDEPFJ_00042 2e-277 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNLDEPFJ_00043 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HNLDEPFJ_00044 4.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HNLDEPFJ_00045 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNLDEPFJ_00046 3.2e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNLDEPFJ_00048 3.2e-95 S reductase
HNLDEPFJ_00049 3.9e-72 badR K Transcriptional regulator, marr family
HNLDEPFJ_00050 5.5e-36 XK27_02060 S Transglycosylase associated protein
HNLDEPFJ_00051 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HNLDEPFJ_00052 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNLDEPFJ_00053 7.5e-14
HNLDEPFJ_00054 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HNLDEPFJ_00055 8.3e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
HNLDEPFJ_00056 3.2e-44 yrzB S Belongs to the UPF0473 family
HNLDEPFJ_00057 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNLDEPFJ_00058 6.3e-44 yrzL S Belongs to the UPF0297 family
HNLDEPFJ_00059 4.2e-217 araT 2.6.1.1 E Aminotransferase
HNLDEPFJ_00060 2.7e-140 recO L Involved in DNA repair and RecF pathway recombination
HNLDEPFJ_00061 4.6e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNLDEPFJ_00062 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNLDEPFJ_00063 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HNLDEPFJ_00064 5.7e-183 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HNLDEPFJ_00065 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNLDEPFJ_00066 3.3e-33
HNLDEPFJ_00067 1.6e-174 1.1.1.169 H Ketopantoate reductase
HNLDEPFJ_00068 2e-135 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNLDEPFJ_00069 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
HNLDEPFJ_00070 2.3e-139 S SseB protein N-terminal domain
HNLDEPFJ_00071 1.2e-236 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HNLDEPFJ_00072 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNLDEPFJ_00073 1.6e-123 yaaA S Belongs to the UPF0246 family
HNLDEPFJ_00074 3.2e-167 XK27_01785 S cog cog1284
HNLDEPFJ_00075 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HNLDEPFJ_00077 8.1e-85 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HNLDEPFJ_00078 1.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNLDEPFJ_00079 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNLDEPFJ_00080 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HNLDEPFJ_00081 1.4e-193 yhjX P Major Facilitator
HNLDEPFJ_00082 4.8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNLDEPFJ_00083 5.1e-205 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HNLDEPFJ_00084 1.7e-134 parB K Belongs to the ParB family
HNLDEPFJ_00085 9.6e-23
HNLDEPFJ_00086 2.3e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HNLDEPFJ_00087 2e-88 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HNLDEPFJ_00088 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNLDEPFJ_00089 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNLDEPFJ_00090 3.5e-71 adcR K transcriptional
HNLDEPFJ_00091 8.3e-136 adcC P ABC transporter, ATP-binding protein
HNLDEPFJ_00092 8.7e-129 adcB P ABC transporter (Permease
HNLDEPFJ_00093 1.6e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HNLDEPFJ_00094 1.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
HNLDEPFJ_00095 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNLDEPFJ_00096 7.7e-47 yajC U protein transport
HNLDEPFJ_00097 1.9e-66 yeeN K transcriptional regulatory protein
HNLDEPFJ_00098 1.9e-23 rpmD J Ribosomal protein L30p/L7e
HNLDEPFJ_00099 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNLDEPFJ_00100 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNLDEPFJ_00101 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNLDEPFJ_00102 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNLDEPFJ_00103 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNLDEPFJ_00104 1.3e-80 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNLDEPFJ_00105 1.1e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNLDEPFJ_00106 1.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNLDEPFJ_00107 1.7e-205 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HNLDEPFJ_00108 5.9e-82 nrdI F Belongs to the NrdI family
HNLDEPFJ_00109 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNLDEPFJ_00111 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNLDEPFJ_00112 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNLDEPFJ_00113 1e-27 ftsI 3.4.16.4 M penicillin-binding protein
HNLDEPFJ_00114 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNLDEPFJ_00116 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNLDEPFJ_00117 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HNLDEPFJ_00118 1e-204 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNLDEPFJ_00119 1.1e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNLDEPFJ_00120 2.8e-263 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNLDEPFJ_00121 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNLDEPFJ_00122 1.2e-40 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
HNLDEPFJ_00123 4.2e-17 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNLDEPFJ_00124 1.5e-91 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNLDEPFJ_00125 2.4e-142 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNLDEPFJ_00126 7e-238 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNLDEPFJ_00127 1.1e-214 pepC 3.4.22.40 E aminopeptidase
HNLDEPFJ_00128 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNLDEPFJ_00129 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNLDEPFJ_00130 3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNLDEPFJ_00131 7.8e-52 purR 2.4.2.22, 2.4.2.7 F operon repressor
HNLDEPFJ_00132 1.8e-21 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNLDEPFJ_00133 2.4e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HNLDEPFJ_00134 6.4e-91 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HNLDEPFJ_00135 1.4e-174 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HNLDEPFJ_00136 1.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
HNLDEPFJ_00137 6.1e-83 mreD M rod shape-determining protein MreD
HNLDEPFJ_00138 6.6e-92 mreC M Involved in formation and maintenance of cell shape
HNLDEPFJ_00139 4.9e-27 S membrane
HNLDEPFJ_00140 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HNLDEPFJ_00141 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HNLDEPFJ_00142 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNLDEPFJ_00143 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
HNLDEPFJ_00144 9.1e-125 fruR K transcriptional
HNLDEPFJ_00145 5.4e-60 D nuclear chromosome segregation
HNLDEPFJ_00146 2.2e-123 glnQ E abc transporter atp-binding protein
HNLDEPFJ_00147 4.2e-273 glnP P ABC transporter
HNLDEPFJ_00148 1.1e-42 ygaC J Belongs to the UPF0374 family
HNLDEPFJ_00149 2.9e-54 ygaC J Belongs to the UPF0374 family
HNLDEPFJ_00150 2.2e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HNLDEPFJ_00151 7.7e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNLDEPFJ_00152 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNLDEPFJ_00153 6.1e-140 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNLDEPFJ_00154 3.8e-134 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNLDEPFJ_00155 7.7e-91 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNLDEPFJ_00156 3.6e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNLDEPFJ_00158 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNLDEPFJ_00159 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNLDEPFJ_00160 9.4e-89 tatD L Hydrolase, tatd
HNLDEPFJ_00161 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
HNLDEPFJ_00162 1.4e-170 rmuC S RmuC domain protein
HNLDEPFJ_00163 2.9e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
HNLDEPFJ_00164 1.1e-58 rplO J binds to the 23S rRNA
HNLDEPFJ_00165 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNLDEPFJ_00166 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNLDEPFJ_00167 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNLDEPFJ_00168 7.8e-15 rpmJ J Ribosomal protein L36
HNLDEPFJ_00169 1.4e-96 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HNLDEPFJ_00170 3.7e-185 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HNLDEPFJ_00171 1.5e-225 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HNLDEPFJ_00172 7.3e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HNLDEPFJ_00173 2.4e-100 S CAAX amino terminal protease family protein
HNLDEPFJ_00174 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNLDEPFJ_00175 1.8e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HNLDEPFJ_00176 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
HNLDEPFJ_00177 1.4e-41 ylxQ J ribosomal protein
HNLDEPFJ_00178 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HNLDEPFJ_00179 8.4e-81 nusA K Participates in both transcription termination and antitermination
HNLDEPFJ_00180 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
HNLDEPFJ_00181 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNLDEPFJ_00182 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNLDEPFJ_00183 5.9e-09 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNLDEPFJ_00184 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNLDEPFJ_00185 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HNLDEPFJ_00186 7e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNLDEPFJ_00187 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HNLDEPFJ_00188 3.3e-118 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNLDEPFJ_00189 1.3e-287 ahpF O alkyl hydroperoxide reductase
HNLDEPFJ_00190 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HNLDEPFJ_00191 8.2e-123 rpsB J Belongs to the universal ribosomal protein uS2 family
HNLDEPFJ_00192 7.9e-230 L Transposase
HNLDEPFJ_00193 1.4e-256 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNLDEPFJ_00194 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNLDEPFJ_00195 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HNLDEPFJ_00196 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNLDEPFJ_00197 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNLDEPFJ_00198 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNLDEPFJ_00199 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNLDEPFJ_00200 6.3e-131 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNLDEPFJ_00201 3.6e-168 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HNLDEPFJ_00202 2.4e-119 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNLDEPFJ_00203 5.5e-301 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNLDEPFJ_00204 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HNLDEPFJ_00205 7.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNLDEPFJ_00206 1.7e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNLDEPFJ_00207 2.2e-43 comGC U Required for transformation and DNA binding
HNLDEPFJ_00208 2.4e-69 cglD NU Competence protein
HNLDEPFJ_00209 5.3e-15 NU Type II secretory pathway pseudopilin
HNLDEPFJ_00212 2e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
HNLDEPFJ_00213 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HNLDEPFJ_00214 1.8e-61 yutD J protein conserved in bacteria
HNLDEPFJ_00215 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNLDEPFJ_00216 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNLDEPFJ_00217 4e-122 atpB C it plays a direct role in the translocation of protons across the membrane
HNLDEPFJ_00218 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNLDEPFJ_00220 5.8e-163 fba 4.1.2.13, 4.1.2.29 G aldolase
HNLDEPFJ_00222 3.9e-96 ywlG S Belongs to the UPF0340 family
HNLDEPFJ_00224 3.4e-72 S QueT transporter
HNLDEPFJ_00225 5.3e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HNLDEPFJ_00226 1.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNLDEPFJ_00227 1.8e-90 K transcriptional regulator
HNLDEPFJ_00228 1.6e-36 yneF S UPF0154 protein
HNLDEPFJ_00229 7.9e-154 fhuR K transcriptional regulator (lysR family)
HNLDEPFJ_00230 4.4e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNLDEPFJ_00231 9.4e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNLDEPFJ_00232 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNLDEPFJ_00234 8.7e-140 ykuT M mechanosensitive ion channel
HNLDEPFJ_00235 3.9e-87 sigH K DNA-templated transcription, initiation
HNLDEPFJ_00236 1.2e-135 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HNLDEPFJ_00237 3e-114 papP P ABC transporter (Permease
HNLDEPFJ_00238 4.6e-107 P ABC transporter (Permease
HNLDEPFJ_00239 5.3e-254 yfmR S abc transporter atp-binding protein
HNLDEPFJ_00240 1.3e-26 U response to pH
HNLDEPFJ_00241 3.5e-118 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HNLDEPFJ_00242 8.7e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNLDEPFJ_00243 1.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNLDEPFJ_00244 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HNLDEPFJ_00245 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HNLDEPFJ_00246 1.9e-96 yloV S kinase related to dihydroxyacetone kinase
HNLDEPFJ_00247 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HNLDEPFJ_00248 3.1e-26 dmpI 5.3.2.6 G Tautomerase enzyme
HNLDEPFJ_00249 2e-107 S Putative adhesin
HNLDEPFJ_00250 5.4e-110 XK27_06930 V domain protein
HNLDEPFJ_00251 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HNLDEPFJ_00252 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNLDEPFJ_00253 1.4e-31 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNLDEPFJ_00254 1.6e-61 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNLDEPFJ_00255 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNLDEPFJ_00256 4.4e-62 rplQ J ribosomal protein l17
HNLDEPFJ_00257 8e-61 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNLDEPFJ_00258 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HNLDEPFJ_00259 1.6e-252 pgi 5.3.1.9 G Belongs to the GPI family
HNLDEPFJ_00260 1.6e-123 sip M LysM domain protein
HNLDEPFJ_00261 3.7e-34 yozE S Belongs to the UPF0346 family
HNLDEPFJ_00262 7.3e-29 cvfB S Protein conserved in bacteria
HNLDEPFJ_00263 7.9e-70 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HNLDEPFJ_00264 1.4e-173 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNLDEPFJ_00265 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HNLDEPFJ_00266 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HNLDEPFJ_00267 1.5e-26 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNLDEPFJ_00268 6e-186 ylbL T Belongs to the peptidase S16 family
HNLDEPFJ_00269 5.4e-183 yhcC S radical SAM protein
HNLDEPFJ_00270 5.8e-247 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HNLDEPFJ_00271 4.7e-58 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNLDEPFJ_00272 1e-84 endA F DNA RNA non-specific endonuclease
HNLDEPFJ_00273 2.9e-111 tcyB_2 P ABC transporter (permease)
HNLDEPFJ_00274 1.9e-116 gltJ P ABC transporter (Permease
HNLDEPFJ_00275 3e-105 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNLDEPFJ_00277 3.9e-99 thiT S Thiamine transporter
HNLDEPFJ_00278 1.2e-238 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNLDEPFJ_00279 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNLDEPFJ_00280 7.3e-115 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNLDEPFJ_00281 5e-54 S HAD hydrolase, family IA, variant
HNLDEPFJ_00282 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNLDEPFJ_00283 1.1e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNLDEPFJ_00284 1.5e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HNLDEPFJ_00285 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HNLDEPFJ_00286 2.5e-203 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNLDEPFJ_00287 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HNLDEPFJ_00288 1.2e-218 metE 2.1.1.14 E Methionine synthase
HNLDEPFJ_00289 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HNLDEPFJ_00290 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HNLDEPFJ_00291 3e-145 amiA E ABC transporter, substrate-binding protein, family 5
HNLDEPFJ_00292 1.6e-49
HNLDEPFJ_00293 1.7e-32
HNLDEPFJ_00294 5.3e-73
HNLDEPFJ_00295 2.3e-240 O MreB/Mbl protein
HNLDEPFJ_00297 5.3e-265 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HNLDEPFJ_00298 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNLDEPFJ_00299 1.9e-176 ecsB U Bacterial ABC transporter protein EcsB
HNLDEPFJ_00300 4.4e-140 ytmP 2.7.1.89 M Phosphotransferase
HNLDEPFJ_00301 1.5e-29 K Helix-turn-helix domain
HNLDEPFJ_00302 1.2e-18
HNLDEPFJ_00303 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HNLDEPFJ_00304 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNLDEPFJ_00305 5.1e-22 K Transcriptional
HNLDEPFJ_00306 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
HNLDEPFJ_00307 4e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HNLDEPFJ_00308 1.1e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HNLDEPFJ_00309 0.0 V ABC transporter (Permease
HNLDEPFJ_00310 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNLDEPFJ_00311 2e-26
HNLDEPFJ_00312 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HNLDEPFJ_00313 3.6e-60 pepO 3.4.24.71 O Peptidase family M13
HNLDEPFJ_00314 3e-38 ptsH G phosphocarrier protein Hpr
HNLDEPFJ_00315 1.6e-297 V abc transporter atp-binding protein
HNLDEPFJ_00316 3.9e-98 XK27_09740 S Phosphoesterase
HNLDEPFJ_00317 1.7e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNLDEPFJ_00318 1.1e-113 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HNLDEPFJ_00319 0.0 clpC O Belongs to the ClpA ClpB family
HNLDEPFJ_00320 2.4e-195 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HNLDEPFJ_00321 3.9e-139 V ABC-type multidrug transport system ATPase and permease
HNLDEPFJ_00322 5.7e-127 3.5.1.28 M domain protein
HNLDEPFJ_00323 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
HNLDEPFJ_00324 6.2e-67 rmaI K Transcriptional regulator, MarR family
HNLDEPFJ_00325 2.8e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HNLDEPFJ_00326 2.3e-50 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNLDEPFJ_00327 6e-91 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNLDEPFJ_00328 8.8e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HNLDEPFJ_00329 1.7e-69 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNLDEPFJ_00330 9.7e-36 XK27_09805 S MORN repeat protein
HNLDEPFJ_00331 1.5e-55 S Psort location Cytoplasmic, score 8.87
HNLDEPFJ_00332 2.6e-87 folE 3.5.4.16 F gtp cyclohydrolase
HNLDEPFJ_00333 7.1e-217 ydaO E amino acid
HNLDEPFJ_00334 1.3e-294 copA 3.6.3.54 P P-type ATPase
HNLDEPFJ_00335 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HNLDEPFJ_00336 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
HNLDEPFJ_00337 6e-149 corA P COG0598 Mg2 and Co2 transporters
HNLDEPFJ_00338 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HNLDEPFJ_00339 1.8e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HNLDEPFJ_00340 5.6e-124
HNLDEPFJ_00341 7.5e-21 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HNLDEPFJ_00342 2.3e-267 pepD E Dipeptidase
HNLDEPFJ_00343 4.1e-110 XK27_10720 D peptidase activity
HNLDEPFJ_00344 6.6e-122 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNLDEPFJ_00345 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNLDEPFJ_00346 1.2e-141 cmpC S abc transporter atp-binding protein
HNLDEPFJ_00347 2.3e-132 WQ51_06230 S ABC transporter
HNLDEPFJ_00348 2.9e-151 degV S DegV family
HNLDEPFJ_00349 1.2e-82 yacP S RNA-binding protein containing a PIN domain
HNLDEPFJ_00350 1.1e-22 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNLDEPFJ_00351 1.4e-62 S MORN repeat variant
HNLDEPFJ_00353 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HNLDEPFJ_00354 6.1e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNLDEPFJ_00355 2.3e-54 cinA 3.5.1.42 S Belongs to the CinA family
HNLDEPFJ_00356 1.9e-53 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNLDEPFJ_00357 1.7e-243 argH 4.3.2.1 E Argininosuccinate lyase
HNLDEPFJ_00358 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HNLDEPFJ_00359 3.6e-45 speD 2.5.1.16, 4.1.1.50 H Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HNLDEPFJ_00362 4.8e-143 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNLDEPFJ_00363 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HNLDEPFJ_00364 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HNLDEPFJ_00365 1.3e-68 lysA 4.1.1.20 E Psort location Cytoplasmic, score 8.87
HNLDEPFJ_00366 4.9e-164 EGP Major facilitator Superfamily
HNLDEPFJ_00367 1.8e-72 copY K negative regulation of transcription, DNA-templated
HNLDEPFJ_00368 9.2e-116 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNLDEPFJ_00369 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNLDEPFJ_00370 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HNLDEPFJ_00371 5.1e-15 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNLDEPFJ_00372 5.7e-252 glnA 6.3.1.2 E glutamine synthetase
HNLDEPFJ_00373 8.8e-27 lanR K sequence-specific DNA binding
HNLDEPFJ_00374 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNLDEPFJ_00375 2.4e-49 L COG1943 Transposase and inactivated derivatives
HNLDEPFJ_00376 3.6e-31 L Integrase core domain protein
HNLDEPFJ_00377 1.3e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HNLDEPFJ_00378 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HNLDEPFJ_00379 7.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNLDEPFJ_00380 3.9e-215 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNLDEPFJ_00381 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HNLDEPFJ_00382 1.6e-109 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNLDEPFJ_00383 1e-104 wecD M Acetyltransferase (GNAT) domain
HNLDEPFJ_00384 3.5e-137 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNLDEPFJ_00385 1.3e-105 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HNLDEPFJ_00386 8.4e-17 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HNLDEPFJ_00387 2e-158 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNLDEPFJ_00388 4e-84 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HNLDEPFJ_00389 2.2e-73 rplI J binds to the 23S rRNA
HNLDEPFJ_00390 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HNLDEPFJ_00391 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNLDEPFJ_00392 9.6e-261 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNLDEPFJ_00393 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
HNLDEPFJ_00394 9.9e-73 sufB O assembly protein SufB
HNLDEPFJ_00395 7.7e-92 lemA S LemA family
HNLDEPFJ_00396 9.1e-16 2.4.1.21 GT5 M Right handed beta helix region
HNLDEPFJ_00398 3.5e-56 lrgA S Effector of murein hydrolase LrgA
HNLDEPFJ_00399 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HNLDEPFJ_00400 2.1e-140 fnt P Formate nitrite transporter
HNLDEPFJ_00401 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
HNLDEPFJ_00402 2.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HNLDEPFJ_00403 3.1e-69 argR K Regulates arginine biosynthesis genes
HNLDEPFJ_00404 5.9e-105 S Oxidoreductase family, NAD-binding Rossmann fold
HNLDEPFJ_00405 3.1e-145 G Domain of Unknown Function (DUF1080)
HNLDEPFJ_00406 1.9e-98 U protein secretion
HNLDEPFJ_00407 3.2e-192 zmpB M signal peptide protein, YSIRK family
HNLDEPFJ_00408 6.7e-80 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNLDEPFJ_00409 5.2e-303 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HNLDEPFJ_00410 1.6e-152 corA P CorA-like protein
HNLDEPFJ_00411 3.7e-149 rarD S Transporter
HNLDEPFJ_00412 9.8e-16 T peptidase
HNLDEPFJ_00413 4.6e-183 amt P Ammonium Transporter
HNLDEPFJ_00414 3.1e-34 amt P Ammonium Transporter
HNLDEPFJ_00415 1.1e-53 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNLDEPFJ_00416 3.6e-73 yccU S CoA-binding protein
HNLDEPFJ_00417 2.4e-50 trxA O Belongs to the thioredoxin family
HNLDEPFJ_00418 6e-143 S Macro domain protein
HNLDEPFJ_00419 9.3e-79 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNLDEPFJ_00420 3.4e-28 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNLDEPFJ_00421 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNLDEPFJ_00422 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HNLDEPFJ_00423 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNLDEPFJ_00424 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNLDEPFJ_00425 6.3e-213 MA20_36090 S Protein of unknown function (DUF2974)
HNLDEPFJ_00426 1.7e-163 fruA 2.7.1.202 G phosphotransferase system
HNLDEPFJ_00427 9.6e-74 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNLDEPFJ_00428 6e-269 clpL O ATP-dependent Clp protease ATP-binding subunit
HNLDEPFJ_00429 7.1e-153 yvjA S membrane
HNLDEPFJ_00430 5.6e-155 rrmA 2.1.1.187 Q methyltransferase
HNLDEPFJ_00431 4.2e-69 ytxH S General stress protein
HNLDEPFJ_00432 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNLDEPFJ_00433 8e-108 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNLDEPFJ_00434 2.5e-34 ylmH S conserved protein, contains S4-like domain
HNLDEPFJ_00435 8.4e-138 divIVA D Cell division initiation protein
HNLDEPFJ_00436 1.9e-88 L COG1943 Transposase and inactivated derivatives
HNLDEPFJ_00437 1.2e-64 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNLDEPFJ_00438 1.8e-114 azlC E AzlC protein
HNLDEPFJ_00439 4.8e-46 azlD S branched-chain amino acid
HNLDEPFJ_00440 4.2e-156 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNLDEPFJ_00441 1.9e-110 serB 3.1.3.3 E phosphoserine phosphatase
HNLDEPFJ_00442 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
HNLDEPFJ_00443 1.2e-211 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNLDEPFJ_00444 7e-218 pyrP F uracil Permease
HNLDEPFJ_00446 8.6e-171 yfjR K regulation of single-species biofilm formation
HNLDEPFJ_00447 4e-284 XK27_10405 S Bacterial membrane protein YfhO
HNLDEPFJ_00448 7.3e-74 L Transposase IS116/IS110/IS902 family
HNLDEPFJ_00449 1.1e-155 S CHAP domain
HNLDEPFJ_00450 1.9e-170 vraS 2.7.13.3 T Histidine kinase
HNLDEPFJ_00451 1.5e-83 yvqF S Membrane
HNLDEPFJ_00452 3.6e-85 pelG M Putative exopolysaccharide Exporter (EPS-E)
HNLDEPFJ_00453 4.1e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNLDEPFJ_00454 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HNLDEPFJ_00455 1.1e-119 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HNLDEPFJ_00456 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNLDEPFJ_00457 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HNLDEPFJ_00458 5.1e-57 yhcA V abc transporter atp-binding protein
HNLDEPFJ_00459 1e-37 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNLDEPFJ_00460 1e-80 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNLDEPFJ_00461 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNLDEPFJ_00462 2.4e-63 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNLDEPFJ_00463 4.5e-52 U protein secretion
HNLDEPFJ_00464 5.9e-109 yvyE 3.4.13.9 S YigZ family
HNLDEPFJ_00465 2.8e-246 L Reverse transcriptase (RNA-dependent DNA polymerase)
HNLDEPFJ_00466 6.4e-265 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HNLDEPFJ_00467 5.1e-165 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HNLDEPFJ_00468 3.7e-160 dcuS 2.7.13.3 T protein histidine kinase activity
HNLDEPFJ_00469 1.1e-223 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNLDEPFJ_00470 2.9e-158 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNLDEPFJ_00471 3.9e-81 lpdA 1.8.1.4 C Dehydrogenase
HNLDEPFJ_00472 1.5e-89 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNLDEPFJ_00473 3.9e-114 S VIT family
HNLDEPFJ_00474 8.2e-97 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNLDEPFJ_00475 1.5e-96 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNLDEPFJ_00476 3.1e-77 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNLDEPFJ_00479 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HNLDEPFJ_00480 2.2e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
HNLDEPFJ_00481 2.3e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HNLDEPFJ_00482 4.2e-141 L PFAM transposase IS116 IS110 IS902 family
HNLDEPFJ_00483 7.2e-65 L Transposase (IS116 IS110 IS902 family)
HNLDEPFJ_00484 1.7e-116 S double-stranded DNA endodeoxyribonuclease activity
HNLDEPFJ_00485 2e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HNLDEPFJ_00486 1.5e-104 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HNLDEPFJ_00489 9e-181 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HNLDEPFJ_00490 3.2e-144 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNLDEPFJ_00491 2.8e-88 malF P ABC transporter (Permease
HNLDEPFJ_00492 5.4e-76 malG P ABC transporter (Permease
HNLDEPFJ_00493 1.5e-52 malG P ABC transporter (Permease
HNLDEPFJ_00494 2.5e-239 purD 6.3.4.13 F Belongs to the GARS family
HNLDEPFJ_00495 1.5e-194 ilvB 2.2.1.6 EH Acetolactate synthase
HNLDEPFJ_00496 6.1e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HNLDEPFJ_00497 5.7e-92 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HNLDEPFJ_00498 6.4e-37 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HNLDEPFJ_00499 1.3e-144
HNLDEPFJ_00500 2e-98 XK27_00765
HNLDEPFJ_00501 5.8e-109 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNLDEPFJ_00502 5.1e-46 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNLDEPFJ_00503 2.4e-176 3.6.3.8 P cation transport ATPase
HNLDEPFJ_00504 5.5e-196 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNLDEPFJ_00505 6.1e-93 XK27_05000 S metal cluster binding
HNLDEPFJ_00506 2.2e-29 liaI KT membrane
HNLDEPFJ_00507 9e-16 S dextransucrase activity
HNLDEPFJ_00508 1.2e-50 S Protein of unknown function (DUF3397)
HNLDEPFJ_00509 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HNLDEPFJ_00510 8.6e-23 2.7.13.3 T GHKL domain
HNLDEPFJ_00511 1.3e-116 yyaQ S YjbR
HNLDEPFJ_00512 6e-73 cbiQ P cobalt transport
HNLDEPFJ_00513 9.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HNLDEPFJ_00514 6.6e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNLDEPFJ_00515 1.5e-117 nudL L hydrolase
HNLDEPFJ_00516 6.3e-54 K transcriptional regulator, PadR family
HNLDEPFJ_00517 4.9e-174 manL 2.7.1.191 G pts system
HNLDEPFJ_00518 4.4e-71 S abc transporter atp-binding protein
HNLDEPFJ_00519 6.2e-48 yxjI S LURP-one-related
HNLDEPFJ_00520 2.4e-93 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNLDEPFJ_00523 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HNLDEPFJ_00524 1.4e-187 tcsA S membrane
HNLDEPFJ_00525 3.5e-213 hsdM 2.1.1.72 V type I restriction-modification system
HNLDEPFJ_00526 1.6e-227 pacL 3.6.3.8 P cation transport ATPase
HNLDEPFJ_00527 2.4e-106 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HNLDEPFJ_00528 3.7e-116 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HNLDEPFJ_00529 3.2e-209 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HNLDEPFJ_00530 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNLDEPFJ_00531 2.9e-48 yhbY J RNA-binding protein
HNLDEPFJ_00532 2.3e-22 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNLDEPFJ_00533 1.3e-117 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HNLDEPFJ_00534 3.6e-16 S Accessory secretory protein Sec, Asp5
HNLDEPFJ_00535 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNLDEPFJ_00536 6.8e-95 ureI S AmiS/UreI family transporter
HNLDEPFJ_00537 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HNLDEPFJ_00538 2.1e-135 cycA E permease
HNLDEPFJ_00539 5e-40 K Acetyltransferase (GNAT) family
HNLDEPFJ_00540 7.4e-112 2.7.6.5 S Region found in RelA / SpoT proteins
HNLDEPFJ_00541 4.7e-143 G COG0457 FOG TPR repeat
HNLDEPFJ_00543 4.2e-156 XK27_03015 S permease
HNLDEPFJ_00544 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HNLDEPFJ_00545 8.7e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HNLDEPFJ_00546 4.3e-33 ykuJ S protein conserved in bacteria
HNLDEPFJ_00547 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HNLDEPFJ_00548 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HNLDEPFJ_00549 2.3e-35 vgrG S Rhs Element Vgr Protein
HNLDEPFJ_00550 2.7e-106 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNLDEPFJ_00551 3e-215 L Transposase
HNLDEPFJ_00552 4.5e-76 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNLDEPFJ_00553 2e-100 pncA Q isochorismatase
HNLDEPFJ_00554 4.4e-80 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNLDEPFJ_00555 9e-197 yceA S Belongs to the UPF0176 family
HNLDEPFJ_00556 7.9e-39 ccl S cog cog4708
HNLDEPFJ_00557 6e-105 nodB3 G deacetylase
HNLDEPFJ_00558 3.2e-104 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNLDEPFJ_00559 5.1e-41 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HNLDEPFJ_00560 3.5e-157 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HNLDEPFJ_00561 1.1e-169 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HNLDEPFJ_00562 1.1e-195 ylbM S Belongs to the UPF0348 family
HNLDEPFJ_00563 7.1e-33 S RloB-like protein
HNLDEPFJ_00564 7.5e-39 3.4.17.14, 3.5.1.28 NU amidase activity
HNLDEPFJ_00565 3.8e-23 3.4.17.14, 3.5.1.28 NU amidase activity
HNLDEPFJ_00566 3.3e-11 divIC D Septum formation initiator
HNLDEPFJ_00567 1.9e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HNLDEPFJ_00568 8.7e-41 gltS ET Belongs to the bacterial solute-binding protein 3 family
HNLDEPFJ_00572 5.3e-184 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HNLDEPFJ_00573 2e-101 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNLDEPFJ_00574 1e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HNLDEPFJ_00576 8.3e-54 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNLDEPFJ_00577 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HNLDEPFJ_00578 1.1e-40 pspC KT PspC domain
HNLDEPFJ_00579 6.8e-16 pspC KT PspC domain protein
HNLDEPFJ_00580 5.2e-119 yqfA K protein, Hemolysin III
HNLDEPFJ_00581 2.1e-166 yjcE P NhaP-type Na H and K H antiporters
HNLDEPFJ_00582 1.9e-07
HNLDEPFJ_00583 2.5e-95 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HNLDEPFJ_00584 6.5e-134 GK ROK family
HNLDEPFJ_00585 2.8e-79 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNLDEPFJ_00586 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HNLDEPFJ_00587 7.1e-167 dnaB L Replication initiation and membrane attachment
HNLDEPFJ_00588 9e-72 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HNLDEPFJ_00589 6.4e-176 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNLDEPFJ_00590 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNLDEPFJ_00591 1.5e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HNLDEPFJ_00592 9.7e-22
HNLDEPFJ_00593 8.4e-78 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNLDEPFJ_00594 1e-66 DegV S DegV family
HNLDEPFJ_00595 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HNLDEPFJ_00596 7.8e-45 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNLDEPFJ_00598 1.2e-39 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNLDEPFJ_00599 2e-107 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNLDEPFJ_00600 3.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNLDEPFJ_00601 8.7e-34 T PhoQ Sensor
HNLDEPFJ_00602 6.1e-82 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HNLDEPFJ_00603 1.5e-36 ylqC L Belongs to the UPF0109 family
HNLDEPFJ_00604 1.5e-138 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNLDEPFJ_00605 1.1e-33 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNLDEPFJ_00606 8.3e-37 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HNLDEPFJ_00607 4.6e-177 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HNLDEPFJ_00608 9.1e-158 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNLDEPFJ_00609 1.4e-160 S dextransucrase activity
HNLDEPFJ_00610 3.7e-120 2.7.7.7 L the current gene model (or a revised gene model) may contain a frame shift
HNLDEPFJ_00612 9.1e-175 potD P spermidine putrescine ABC transporter
HNLDEPFJ_00613 8.3e-75 adcA P Belongs to the bacterial solute-binding protein 9 family
HNLDEPFJ_00614 2.6e-140 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HNLDEPFJ_00615 1.2e-132 hpk9 2.7.13.3 T protein histidine kinase activity
HNLDEPFJ_00616 3.8e-198 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNLDEPFJ_00617 1.1e-37 rimP S Required for maturation of 30S ribosomal subunits
HNLDEPFJ_00618 1.5e-64 pheS 6.1.1.20 J Aminoacyl tRNA synthetase class II, N-terminal domain
HNLDEPFJ_00619 1.9e-37 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNLDEPFJ_00620 1.5e-45 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNLDEPFJ_00621 1.1e-167 XK27_09615 C reductase
HNLDEPFJ_00622 8.9e-153 yitS S EDD domain protein, DegV family
HNLDEPFJ_00623 5e-63 WQ51_03320 S cog cog4835
HNLDEPFJ_00624 8.7e-13
HNLDEPFJ_00625 3e-133 S hydrolase
HNLDEPFJ_00626 5.6e-19 fruA 2.7.1.202 G phosphotransferase system
HNLDEPFJ_00627 4.8e-99 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNLDEPFJ_00628 2.1e-13 rplD J Forms part of the polypeptide exit tunnel
HNLDEPFJ_00629 9.2e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNLDEPFJ_00630 6.8e-116 K Response regulator receiver domain protein
HNLDEPFJ_00631 5.3e-189 yegQ O Peptidase U32
HNLDEPFJ_00632 4.2e-53 yheA S Belongs to the UPF0342 family
HNLDEPFJ_00633 8.7e-198 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HNLDEPFJ_00634 9.6e-142 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HNLDEPFJ_00635 7e-28 M Putative cell wall binding repeat
HNLDEPFJ_00636 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNLDEPFJ_00637 7.5e-89 S unusual protein kinase
HNLDEPFJ_00638 1.8e-133 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNLDEPFJ_00639 6.4e-38 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNLDEPFJ_00642 2.2e-27 XK27_05745
HNLDEPFJ_00643 1.4e-84 E Alpha beta hydrolase
HNLDEPFJ_00644 7e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HNLDEPFJ_00645 3e-84 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HNLDEPFJ_00646 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNLDEPFJ_00647 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
HNLDEPFJ_00648 3.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HNLDEPFJ_00649 2e-143 oppD P Belongs to the ABC transporter superfamily
HNLDEPFJ_00650 5.8e-141 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HNLDEPFJ_00651 2.6e-97 dltB M Membrane protein involved in D-alanine export
HNLDEPFJ_00652 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNLDEPFJ_00653 5.8e-55 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNLDEPFJ_00654 1.4e-63 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HNLDEPFJ_00655 7.7e-67 ywiB S Domain of unknown function (DUF1934)
HNLDEPFJ_00656 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNLDEPFJ_00657 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNLDEPFJ_00658 3.3e-71 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HNLDEPFJ_00659 3.7e-108 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNLDEPFJ_00660 2.7e-62 norN V Mate efflux family protein
HNLDEPFJ_00661 9.5e-38 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HNLDEPFJ_00662 1.7e-75 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNLDEPFJ_00663 3.1e-157 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNLDEPFJ_00664 2.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNLDEPFJ_00665 1.3e-39 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNLDEPFJ_00666 3.1e-101 M domain protein
HNLDEPFJ_00667 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HNLDEPFJ_00668 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNLDEPFJ_00670 2.8e-18 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)