ORF_ID e_value Gene_name EC_number CAZy COGs Description
HNAFNGMG_00001 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HNAFNGMG_00002 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HNAFNGMG_00003 3.2e-29 yyzM S Protein conserved in bacteria
HNAFNGMG_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HNAFNGMG_00005 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HNAFNGMG_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HNAFNGMG_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HNAFNGMG_00008 3e-60 divIC D Septum formation initiator
HNAFNGMG_00010 3.2e-234 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HNAFNGMG_00011 7.7e-233 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HNAFNGMG_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HNAFNGMG_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HNAFNGMG_00026 2.6e-10
HNAFNGMG_00032 2.4e-110 mreC M Involved in formation and maintenance of cell shape
HNAFNGMG_00033 7.4e-81 mreD M rod shape-determining protein MreD
HNAFNGMG_00034 1.9e-84 usp 3.5.1.28 CBM50 S CHAP domain
HNAFNGMG_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNAFNGMG_00036 4.7e-216 araT 2.6.1.1 E Aminotransferase
HNAFNGMG_00037 8e-140 recO L Involved in DNA repair and RecF pathway recombination
HNAFNGMG_00038 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HNAFNGMG_00039 1.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNAFNGMG_00040 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HNAFNGMG_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HNAFNGMG_00042 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HNAFNGMG_00043 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HNAFNGMG_00044 1.3e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HNAFNGMG_00045 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HNAFNGMG_00046 5e-156 S CHAP domain
HNAFNGMG_00047 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
HNAFNGMG_00048 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HNAFNGMG_00049 5.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HNAFNGMG_00050 2.1e-174 1.1.1.169 H Ketopantoate reductase
HNAFNGMG_00051 4.2e-33
HNAFNGMG_00052 1.8e-84
HNAFNGMG_00053 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HNAFNGMG_00055 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HNAFNGMG_00056 3.4e-68 argR K Regulates arginine biosynthesis genes
HNAFNGMG_00057 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HNAFNGMG_00058 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HNAFNGMG_00059 1.5e-77 S Protein of unknown function (DUF3021)
HNAFNGMG_00060 1.1e-69 K LytTr DNA-binding domain
HNAFNGMG_00062 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HNAFNGMG_00064 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HNAFNGMG_00065 7.3e-103 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HNAFNGMG_00066 1.7e-224 cinA 3.5.1.42 S Belongs to the CinA family
HNAFNGMG_00067 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HNAFNGMG_00068 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HNAFNGMG_00074 1.9e-07
HNAFNGMG_00079 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNAFNGMG_00080 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HNAFNGMG_00081 1.2e-35 XK27_02060 S Transglycosylase associated protein
HNAFNGMG_00082 1.5e-71 badR K Transcriptional regulator, marr family
HNAFNGMG_00083 3.2e-95 S reductase
HNAFNGMG_00085 1.4e-284 ahpF O alkyl hydroperoxide reductase
HNAFNGMG_00086 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HNAFNGMG_00087 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HNAFNGMG_00088 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HNAFNGMG_00089 1.6e-82 S Putative small multi-drug export protein
HNAFNGMG_00090 3.1e-75 ctsR K Belongs to the CtsR family
HNAFNGMG_00091 0.0 clpC O Belongs to the ClpA ClpB family
HNAFNGMG_00092 2.2e-232 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HNAFNGMG_00093 1.6e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HNAFNGMG_00094 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HNAFNGMG_00095 4.7e-140 S SseB protein N-terminal domain
HNAFNGMG_00096 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
HNAFNGMG_00098 3.1e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNAFNGMG_00099 3.6e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HNAFNGMG_00101 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNAFNGMG_00102 6e-91 yacP S RNA-binding protein containing a PIN domain
HNAFNGMG_00103 5.4e-153 degV S DegV family
HNAFNGMG_00105 5.1e-22 K Transcriptional
HNAFNGMG_00106 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HNAFNGMG_00107 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HNAFNGMG_00108 6e-191 L Phage integrase family
HNAFNGMG_00109 2.5e-23
HNAFNGMG_00112 3.3e-148 repB EP Plasmid replication protein
HNAFNGMG_00114 1.6e-09
HNAFNGMG_00115 8.7e-180 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HNAFNGMG_00116 2.5e-10
HNAFNGMG_00117 4.5e-171 D nuclear chromosome segregation
HNAFNGMG_00120 1.3e-17
HNAFNGMG_00121 1.5e-29 K Helix-turn-helix domain
HNAFNGMG_00123 8.6e-148 srtB 3.4.22.70 S Sortase family
HNAFNGMG_00124 2.5e-233 capA M Bacterial capsule synthesis protein
HNAFNGMG_00125 2.3e-38 gcvR T UPF0237 protein
HNAFNGMG_00126 2.5e-242 XK27_08635 S UPF0210 protein
HNAFNGMG_00127 1.8e-130 ais G Phosphoglycerate mutase
HNAFNGMG_00128 1.8e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HNAFNGMG_00129 9.7e-98 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HNAFNGMG_00130 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HNAFNGMG_00131 9.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HNAFNGMG_00132 1.4e-304 dnaK O Heat shock 70 kDa protein
HNAFNGMG_00133 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HNAFNGMG_00134 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HNAFNGMG_00135 3.8e-134 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HNAFNGMG_00136 1.1e-78 hmpT S cog cog4720
HNAFNGMG_00151 3.9e-87 sigH K DNA-templated transcription, initiation
HNAFNGMG_00152 2.3e-134 ykuT M mechanosensitive ion channel
HNAFNGMG_00153 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HNAFNGMG_00154 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HNAFNGMG_00155 2.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HNAFNGMG_00156 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
HNAFNGMG_00157 7.8e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HNAFNGMG_00158 1.3e-57 XK27_02675 K Acetyltransferase GNAT Family
HNAFNGMG_00159 3.5e-177 prmA J Ribosomal protein L11 methyltransferase
HNAFNGMG_00160 7.7e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HNAFNGMG_00161 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HNAFNGMG_00162 9.1e-83 nrdI F Belongs to the NrdI family
HNAFNGMG_00163 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HNAFNGMG_00164 2.4e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HNAFNGMG_00165 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HNAFNGMG_00166 7.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HNAFNGMG_00167 1.9e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HNAFNGMG_00168 1.1e-102 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HNAFNGMG_00169 7.4e-182 yhjX P Major Facilitator
HNAFNGMG_00170 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HNAFNGMG_00171 4.4e-82 V VanZ like family
HNAFNGMG_00172 1.8e-180 D nuclear chromosome segregation
HNAFNGMG_00173 2.2e-123 glnQ E abc transporter atp-binding protein
HNAFNGMG_00174 4.3e-270 glnP P ABC transporter
HNAFNGMG_00175 4.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HNAFNGMG_00176 4.1e-17 S Protein of unknown function (DUF3021)
HNAFNGMG_00177 1e-123 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HNAFNGMG_00178 7.4e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
HNAFNGMG_00179 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HNAFNGMG_00180 6.9e-234 sufD O assembly protein SufD
HNAFNGMG_00181 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HNAFNGMG_00182 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
HNAFNGMG_00183 2.9e-273 sufB O assembly protein SufB
HNAFNGMG_00184 4.7e-26
HNAFNGMG_00185 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HNAFNGMG_00186 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HNAFNGMG_00187 1e-70 adcR K transcriptional
HNAFNGMG_00188 7.1e-135 adcC P ABC transporter, ATP-binding protein
HNAFNGMG_00189 1.9e-128 adcB P ABC transporter (Permease
HNAFNGMG_00190 2.9e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HNAFNGMG_00191 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_00192 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HNAFNGMG_00193 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HNAFNGMG_00194 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAFNGMG_00195 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HNAFNGMG_00196 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
HNAFNGMG_00197 1.1e-95 srlA G PTS system glucitol sorbitol-specific
HNAFNGMG_00198 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
HNAFNGMG_00199 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
HNAFNGMG_00200 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
HNAFNGMG_00201 9.2e-59 L MULE transposase domain
HNAFNGMG_00202 1.1e-108 L Transposase IS116 IS110 IS902
HNAFNGMG_00203 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNAFNGMG_00204 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_00205 1.4e-153 Z012_04635 K sequence-specific DNA binding
HNAFNGMG_00206 1.1e-276 V ABC transporter
HNAFNGMG_00207 6.1e-126 yeeN K transcriptional regulatory protein
HNAFNGMG_00208 2.9e-46 yajC U protein transport
HNAFNGMG_00209 7.2e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HNAFNGMG_00210 6.7e-142 cdsA 2.7.7.41 S Belongs to the CDS family
HNAFNGMG_00211 3.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HNAFNGMG_00212 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HNAFNGMG_00213 0.0 WQ51_06230 S ABC transporter
HNAFNGMG_00214 5.2e-142 cmpC S abc transporter atp-binding protein
HNAFNGMG_00215 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HNAFNGMG_00216 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HNAFNGMG_00218 1.5e-44
HNAFNGMG_00219 7.6e-55 S TM2 domain
HNAFNGMG_00220 3.5e-160 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNAFNGMG_00221 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNAFNGMG_00222 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HNAFNGMG_00223 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HNAFNGMG_00224 4.3e-69 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HNAFNGMG_00225 2.5e-144 cof S Sucrose-6F-phosphate phosphohydrolase
HNAFNGMG_00226 6.5e-134 glcR K transcriptional regulator (DeoR family)
HNAFNGMG_00227 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HNAFNGMG_00228 6.5e-73 K transcriptional
HNAFNGMG_00229 3.7e-224 S COG1073 Hydrolases of the alpha beta superfamily
HNAFNGMG_00230 4.7e-38 yjdF S Protein of unknown function (DUF2992)
HNAFNGMG_00231 2.2e-45 3.2.2.21 S YCII-related domain
HNAFNGMG_00232 1.5e-52 K regulation of RNA biosynthetic process
HNAFNGMG_00233 1.3e-154 cylA V abc transporter atp-binding protein
HNAFNGMG_00234 9.3e-134 cylB V ABC-2 type transporter
HNAFNGMG_00235 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
HNAFNGMG_00236 4.8e-30 S Protein of unknown function (DUF3021)
HNAFNGMG_00237 5.8e-121 mta K Transcriptional
HNAFNGMG_00238 2.4e-119 yhcA V abc transporter atp-binding protein
HNAFNGMG_00239 3e-216 macB_2 V FtsX-like permease family
HNAFNGMG_00240 1.1e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HNAFNGMG_00241 2e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HNAFNGMG_00242 2.9e-70 yhaI S Protein of unknown function (DUF805)
HNAFNGMG_00243 8.4e-254 pepC 3.4.22.40 E aminopeptidase
HNAFNGMG_00244 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNAFNGMG_00245 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HNAFNGMG_00246 9.8e-94 ypsA S Belongs to the UPF0398 family
HNAFNGMG_00247 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HNAFNGMG_00248 3.7e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HNAFNGMG_00249 1.2e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HNAFNGMG_00250 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HNAFNGMG_00251 4.8e-22
HNAFNGMG_00252 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HNAFNGMG_00253 1e-84 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HNAFNGMG_00254 3.1e-289 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HNAFNGMG_00255 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HNAFNGMG_00256 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNAFNGMG_00257 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HNAFNGMG_00258 2.3e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HNAFNGMG_00259 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HNAFNGMG_00260 2.1e-99 ybhL S Belongs to the BI1 family
HNAFNGMG_00261 3.2e-12 ycdA S Domain of unknown function (DUF4352)
HNAFNGMG_00262 6.9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HNAFNGMG_00263 4.1e-90 K transcriptional regulator
HNAFNGMG_00264 1.6e-36 yneF S UPF0154 protein
HNAFNGMG_00265 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HNAFNGMG_00266 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HNAFNGMG_00267 1.6e-96 XK27_09740 S Phosphoesterase
HNAFNGMG_00268 2.7e-85 ykuL S CBS domain
HNAFNGMG_00269 1e-126 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HNAFNGMG_00270 5.3e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HNAFNGMG_00271 2.6e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HNAFNGMG_00272 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNAFNGMG_00273 1.8e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
HNAFNGMG_00274 1e-257 trkH P Cation transport protein
HNAFNGMG_00275 1e-246 trkA P Potassium transporter peripheral membrane component
HNAFNGMG_00276 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HNAFNGMG_00277 2.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HNAFNGMG_00278 5.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HNAFNGMG_00279 7.1e-156 K sequence-specific DNA binding
HNAFNGMG_00280 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HNAFNGMG_00281 2.4e-53 yhaI L Membrane
HNAFNGMG_00282 2.1e-244 S Domain of unknown function (DUF4173)
HNAFNGMG_00283 6.8e-95 ureI S AmiS/UreI family transporter
HNAFNGMG_00284 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HNAFNGMG_00285 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HNAFNGMG_00286 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HNAFNGMG_00287 6.6e-78 ureE O enzyme active site formation
HNAFNGMG_00288 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HNAFNGMG_00289 4.7e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HNAFNGMG_00290 1.5e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HNAFNGMG_00291 3.3e-175 cbiM P biosynthesis protein CbiM
HNAFNGMG_00292 5.4e-136 P cobalt transport protein
HNAFNGMG_00293 7.7e-129 cbiO P ABC transporter
HNAFNGMG_00294 6.3e-138 ET ABC transporter substrate-binding protein
HNAFNGMG_00295 1.6e-163 metQ M Belongs to the NlpA lipoprotein family
HNAFNGMG_00296 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HNAFNGMG_00297 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HNAFNGMG_00298 1.2e-99 metI P ABC transporter (Permease
HNAFNGMG_00299 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HNAFNGMG_00300 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HNAFNGMG_00301 8e-94 S UPF0397 protein
HNAFNGMG_00302 9.6e-308 ykoD P abc transporter atp-binding protein
HNAFNGMG_00303 1.9e-147 cbiQ P cobalt transport
HNAFNGMG_00304 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
HNAFNGMG_00305 1.1e-232 P COG0168 Trk-type K transport systems, membrane components
HNAFNGMG_00306 1.2e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HNAFNGMG_00307 1.5e-89 yceD K metal-binding, possibly nucleic acid-binding protein
HNAFNGMG_00308 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNAFNGMG_00309 2.5e-278 T PhoQ Sensor
HNAFNGMG_00310 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HNAFNGMG_00311 2e-211 dnaB L Replication initiation and membrane attachment
HNAFNGMG_00312 2.4e-164 dnaI L Primosomal protein DnaI
HNAFNGMG_00313 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HNAFNGMG_00314 1.2e-104
HNAFNGMG_00315 1.8e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HNAFNGMG_00316 2.5e-62 manO S protein conserved in bacteria
HNAFNGMG_00317 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
HNAFNGMG_00318 4.5e-117 manM G pts system
HNAFNGMG_00319 4.9e-174 manL 2.7.1.191 G pts system
HNAFNGMG_00320 7.7e-67 manO S Protein conserved in bacteria
HNAFNGMG_00321 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
HNAFNGMG_00322 4.7e-135 manY G pts system
HNAFNGMG_00323 6.2e-169 manL 2.7.1.191 G pts system
HNAFNGMG_00324 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HNAFNGMG_00325 1.3e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HNAFNGMG_00326 6.2e-247 pbuO S permease
HNAFNGMG_00327 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HNAFNGMG_00328 1.1e-87 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HNAFNGMG_00329 9.8e-188 brpA K Transcriptional
HNAFNGMG_00330 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
HNAFNGMG_00331 2.4e-196 nusA K Participates in both transcription termination and antitermination
HNAFNGMG_00332 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HNAFNGMG_00333 8e-42 ylxQ J ribosomal protein
HNAFNGMG_00334 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HNAFNGMG_00335 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HNAFNGMG_00336 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HNAFNGMG_00337 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HNAFNGMG_00338 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HNAFNGMG_00339 1.3e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HNAFNGMG_00340 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HNAFNGMG_00341 7.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
HNAFNGMG_00342 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HNAFNGMG_00343 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HNAFNGMG_00344 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HNAFNGMG_00345 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HNAFNGMG_00346 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HNAFNGMG_00347 3.2e-72 ylbF S Belongs to the UPF0342 family
HNAFNGMG_00348 7.1e-46 ylbG S UPF0298 protein
HNAFNGMG_00349 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HNAFNGMG_00350 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
HNAFNGMG_00351 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
HNAFNGMG_00352 2.4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HNAFNGMG_00353 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HNAFNGMG_00354 9.6e-110 acuB S CBS domain
HNAFNGMG_00355 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HNAFNGMG_00356 2.9e-108 yvyE 3.4.13.9 S YigZ family
HNAFNGMG_00357 5.7e-239 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HNAFNGMG_00358 6.5e-98 comFC K competence protein
HNAFNGMG_00359 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HNAFNGMG_00368 1.1e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
HNAFNGMG_00369 2.8e-103 S Domain of unknown function (DUF1803)
HNAFNGMG_00370 7.8e-102 ygaC J Belongs to the UPF0374 family
HNAFNGMG_00371 4.1e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
HNAFNGMG_00372 2.6e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNAFNGMG_00373 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
HNAFNGMG_00374 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
HNAFNGMG_00375 2.8e-114 S HAD hydrolase, family IA, variant 3
HNAFNGMG_00376 4.8e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HNAFNGMG_00377 5.2e-72 marR K Transcriptional regulator, MarR family
HNAFNGMG_00378 3.2e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HNAFNGMG_00379 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HNAFNGMG_00380 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HNAFNGMG_00381 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HNAFNGMG_00382 6.2e-126 IQ reductase
HNAFNGMG_00383 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HNAFNGMG_00384 9.4e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HNAFNGMG_00385 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HNAFNGMG_00386 3.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HNAFNGMG_00387 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HNAFNGMG_00388 1.8e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HNAFNGMG_00389 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HNAFNGMG_00390 1.2e-206 rny D Endoribonuclease that initiates mRNA decay
HNAFNGMG_00391 3.1e-125 fruR K transcriptional
HNAFNGMG_00392 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HNAFNGMG_00393 0.0 fruA 2.7.1.202 G phosphotransferase system
HNAFNGMG_00394 5.9e-255 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNAFNGMG_00395 1.2e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HNAFNGMG_00397 1.7e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HNAFNGMG_00398 9.7e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HNAFNGMG_00399 3.1e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HNAFNGMG_00400 7.7e-252 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HNAFNGMG_00401 6.2e-83 2.3.1.128 K acetyltransferase
HNAFNGMG_00402 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HNAFNGMG_00403 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HNAFNGMG_00404 2.7e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HNAFNGMG_00405 5e-63 WQ51_03320 S cog cog4835
HNAFNGMG_00406 2.8e-146 XK27_08360 S EDD domain protein, DegV family
HNAFNGMG_00407 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HNAFNGMG_00408 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HNAFNGMG_00409 0.0 yfmR S abc transporter atp-binding protein
HNAFNGMG_00410 5e-26 U response to pH
HNAFNGMG_00411 2.4e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HNAFNGMG_00412 1.8e-43 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HNAFNGMG_00413 1e-153 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HNAFNGMG_00414 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HNAFNGMG_00415 1.9e-268 S Psort location CytoplasmicMembrane, score
HNAFNGMG_00416 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HNAFNGMG_00417 4.4e-74 K DNA-binding transcription factor activity
HNAFNGMG_00418 5.5e-309 lmrA1 V abc transporter atp-binding protein
HNAFNGMG_00419 0.0 lmrA2 V abc transporter atp-binding protein
HNAFNGMG_00420 2.6e-109 K Acetyltransferase (GNAT) family
HNAFNGMG_00421 2.8e-111 2.7.6.5 S Region found in RelA / SpoT proteins
HNAFNGMG_00422 2.7e-115 T response regulator
HNAFNGMG_00423 4.4e-209 sptS 2.7.13.3 T Histidine kinase
HNAFNGMG_00424 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HNAFNGMG_00425 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HNAFNGMG_00426 8.5e-159 cvfB S Protein conserved in bacteria
HNAFNGMG_00427 3.7e-34 yozE S Belongs to the UPF0346 family
HNAFNGMG_00428 3.9e-128 sip M LysM domain protein
HNAFNGMG_00429 3.7e-188 phoH T phosphate starvation-inducible protein PhoH
HNAFNGMG_00435 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HNAFNGMG_00436 2.9e-159 S reductase
HNAFNGMG_00437 5.2e-167 K transcriptional regulator (lysR family)
HNAFNGMG_00438 1e-104 S CAAX amino terminal protease family protein
HNAFNGMG_00439 3.2e-278 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNAFNGMG_00440 5.2e-165 coiA 3.6.4.12 S Competence protein
HNAFNGMG_00441 0.0 pepF E oligoendopeptidase F
HNAFNGMG_00442 5.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
HNAFNGMG_00443 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
HNAFNGMG_00444 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HNAFNGMG_00445 3e-84 yxjI S LURP-one-related
HNAFNGMG_00446 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HNAFNGMG_00449 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HNAFNGMG_00450 1.8e-133 agrA KT phosphorelay signal transduction system
HNAFNGMG_00451 1.5e-142 2.7.13.3 T GHKL domain
HNAFNGMG_00452 3.6e-68 2.7.13.3 T GHKL domain
HNAFNGMG_00455 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HNAFNGMG_00456 2.2e-137 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HNAFNGMG_00457 4.4e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HNAFNGMG_00458 8e-180 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HNAFNGMG_00459 9.5e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HNAFNGMG_00460 3.8e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HNAFNGMG_00461 2e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HNAFNGMG_00462 7.2e-129 yxkH G deacetylase
HNAFNGMG_00463 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HNAFNGMG_00464 5.9e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HNAFNGMG_00465 5.3e-148 rarD S Transporter
HNAFNGMG_00466 4e-17 T peptidase
HNAFNGMG_00467 1.4e-14 coiA 3.6.4.12 S Competence protein
HNAFNGMG_00470 4e-104 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HNAFNGMG_00471 3e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HNAFNGMG_00472 1.5e-95 F AAA domain
HNAFNGMG_00473 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HNAFNGMG_00474 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNAFNGMG_00475 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
HNAFNGMG_00476 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HNAFNGMG_00477 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HNAFNGMG_00478 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HNAFNGMG_00479 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HNAFNGMG_00480 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HNAFNGMG_00481 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HNAFNGMG_00482 3.5e-217 ftsW D Belongs to the SEDS family
HNAFNGMG_00483 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HNAFNGMG_00484 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HNAFNGMG_00485 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HNAFNGMG_00487 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HNAFNGMG_00488 2.7e-160 holB 2.7.7.7 L dna polymerase iii
HNAFNGMG_00489 4.4e-133 yaaT S stage 0 sporulation protein
HNAFNGMG_00490 1.2e-54 yabA L Involved in initiation control of chromosome replication
HNAFNGMG_00491 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HNAFNGMG_00492 1.8e-148 amt P Ammonium Transporter
HNAFNGMG_00493 2.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
HNAFNGMG_00494 1.2e-141 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HNAFNGMG_00495 2e-75 S Bacterial inner membrane protein
HNAFNGMG_00496 5.2e-113 3.4.17.14, 3.5.1.28 NU amidase activity
HNAFNGMG_00497 3.5e-294 nptA P COG1283 Na phosphate symporter
HNAFNGMG_00498 5.7e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HNAFNGMG_00499 9.6e-220 S membrane
HNAFNGMG_00500 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HNAFNGMG_00501 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HNAFNGMG_00502 1.3e-38 ynzC S UPF0291 protein
HNAFNGMG_00503 1.1e-251 cycA E permease
HNAFNGMG_00504 9.2e-09 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAFNGMG_00505 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_00506 6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNAFNGMG_00510 5.8e-69 K Helix-turn-helix
HNAFNGMG_00511 1.6e-41
HNAFNGMG_00513 1.2e-166 fhuR K transcriptional regulator (lysR family)
HNAFNGMG_00514 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HNAFNGMG_00515 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HNAFNGMG_00516 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HNAFNGMG_00517 1.8e-221 pyrP F uracil Permease
HNAFNGMG_00518 3.8e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HNAFNGMG_00519 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HNAFNGMG_00520 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HNAFNGMG_00521 1.6e-124 2.1.1.223 S Putative SAM-dependent methyltransferase
HNAFNGMG_00522 9.8e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HNAFNGMG_00523 3.4e-121 macB V ABC transporter, ATP-binding protein
HNAFNGMG_00524 6.5e-213 V permease protein
HNAFNGMG_00525 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HNAFNGMG_00526 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HNAFNGMG_00528 2e-23 M Psort location Cytoplasmic, score
HNAFNGMG_00529 7.7e-242 3.5.1.28 NU GBS Bsp-like repeat
HNAFNGMG_00531 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HNAFNGMG_00532 1.8e-48 L COG3547 Transposase and inactivated derivatives
HNAFNGMG_00533 7.5e-231 2.7.13.3 T GHKL domain
HNAFNGMG_00534 1.3e-131 agrA KT Response regulator of the LytR AlgR family
HNAFNGMG_00536 2.1e-21 S Antitoxin component of a toxin-antitoxin (TA) module
HNAFNGMG_00537 9.5e-31 XK27_00530 M CHAP domain protein
HNAFNGMG_00538 6.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
HNAFNGMG_00539 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HNAFNGMG_00540 0.0 mdlB V abc transporter atp-binding protein
HNAFNGMG_00541 0.0 lmrA V abc transporter atp-binding protein
HNAFNGMG_00542 2.1e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HNAFNGMG_00543 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HNAFNGMG_00544 6.9e-197 yceA S Belongs to the UPF0176 family
HNAFNGMG_00545 1.6e-28 XK27_00085 K Transcriptional
HNAFNGMG_00546 9.3e-25
HNAFNGMG_00547 3.9e-114 S VIT family
HNAFNGMG_00548 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNAFNGMG_00549 6.5e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HNAFNGMG_00550 6.6e-196 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HNAFNGMG_00552 5.6e-120 E alpha/beta hydrolase fold
HNAFNGMG_00553 5.9e-47 T peptidase
HNAFNGMG_00554 1.3e-109 T Response regulator receiver domain protein
HNAFNGMG_00555 3e-179 ybdK T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HNAFNGMG_00556 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HNAFNGMG_00557 1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HNAFNGMG_00558 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HNAFNGMG_00559 4.9e-166 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HNAFNGMG_00560 3.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HNAFNGMG_00561 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HNAFNGMG_00562 9.3e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HNAFNGMG_00563 1.2e-94 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HNAFNGMG_00564 1.5e-21
HNAFNGMG_00565 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HNAFNGMG_00566 0.0 U protein secretion
HNAFNGMG_00567 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HNAFNGMG_00568 5.7e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HNAFNGMG_00570 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HNAFNGMG_00571 2.1e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HNAFNGMG_00572 8.5e-193 S Protein of unknown function (DUF3114)
HNAFNGMG_00573 4.1e-29 pspC KT PspC domain protein
HNAFNGMG_00574 1.2e-118 yqfA K protein, Hemolysin III
HNAFNGMG_00575 3e-78 K hmm pf08876
HNAFNGMG_00576 4.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HNAFNGMG_00577 1.6e-208 mvaS 2.3.3.10 I synthase
HNAFNGMG_00578 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HNAFNGMG_00579 1.2e-88 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HNAFNGMG_00580 9.7e-22
HNAFNGMG_00581 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HNAFNGMG_00582 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HNAFNGMG_00583 8.3e-249 mmuP E amino acid
HNAFNGMG_00584 1.3e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HNAFNGMG_00585 2.2e-30 S Domain of unknown function (DUF1912)
HNAFNGMG_00586 6.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
HNAFNGMG_00587 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HNAFNGMG_00588 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNAFNGMG_00590 7.4e-12
HNAFNGMG_00591 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HNAFNGMG_00592 4.5e-199 ilvE 2.6.1.42 E Aminotransferase
HNAFNGMG_00593 3.3e-17 S Protein of unknown function (DUF2969)
HNAFNGMG_00596 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HNAFNGMG_00599 7.1e-107 S Domain of Unknown Function with PDB structure (DUF3862)
HNAFNGMG_00600 2.4e-116 M Pfam SNARE associated Golgi protein
HNAFNGMG_00601 9.5e-228 murN 2.3.2.16 V FemAB family
HNAFNGMG_00602 1.2e-172 S oxidoreductase
HNAFNGMG_00603 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
HNAFNGMG_00604 6.3e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HNAFNGMG_00605 0.0 clpE O Belongs to the ClpA ClpB family
HNAFNGMG_00606 1.8e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HNAFNGMG_00607 1e-34 ykuJ S protein conserved in bacteria
HNAFNGMG_00608 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HNAFNGMG_00609 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_00610 9.1e-78 feoA P FeoA domain protein
HNAFNGMG_00611 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HNAFNGMG_00612 6.6e-08
HNAFNGMG_00613 1.3e-150 I Alpha/beta hydrolase family
HNAFNGMG_00614 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HNAFNGMG_00615 6.2e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HNAFNGMG_00616 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HNAFNGMG_00617 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HNAFNGMG_00618 2.4e-139 licT K antiterminator
HNAFNGMG_00619 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HNAFNGMG_00620 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HNAFNGMG_00621 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HNAFNGMG_00622 1.5e-141 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HNAFNGMG_00623 1.5e-101 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HNAFNGMG_00624 2.7e-222 mdtG EGP Major facilitator Superfamily
HNAFNGMG_00625 2e-33 secG U Preprotein translocase subunit SecG
HNAFNGMG_00626 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HNAFNGMG_00627 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HNAFNGMG_00628 4.8e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HNAFNGMG_00629 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HNAFNGMG_00630 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HNAFNGMG_00631 2.4e-181 ccpA K Catabolite control protein A
HNAFNGMG_00632 3.6e-199 yyaQ S YjbR
HNAFNGMG_00633 1.9e-195 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HNAFNGMG_00634 8.7e-78 yueI S Protein of unknown function (DUF1694)
HNAFNGMG_00635 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HNAFNGMG_00636 4.6e-25 WQ51_00785
HNAFNGMG_00637 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HNAFNGMG_00638 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
HNAFNGMG_00639 4.4e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HNAFNGMG_00640 2.2e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HNAFNGMG_00641 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HNAFNGMG_00642 1.9e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HNAFNGMG_00643 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HNAFNGMG_00644 4.2e-53 yheA S Belongs to the UPF0342 family
HNAFNGMG_00645 9.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HNAFNGMG_00646 1.2e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HNAFNGMG_00647 5e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HNAFNGMG_00648 1.7e-151 pheA 4.2.1.51 E Prephenate dehydratase
HNAFNGMG_00649 2e-245 msrR K Transcriptional regulator
HNAFNGMG_00650 4.5e-153 ydiA P C4-dicarboxylate transporter malic acid transport protein
HNAFNGMG_00651 1.1e-200 I acyl-CoA dehydrogenase
HNAFNGMG_00652 2e-97 mip S hydroperoxide reductase activity
HNAFNGMG_00653 3.2e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HNAFNGMG_00654 4.3e-22
HNAFNGMG_00655 2e-217 EGP Transmembrane secretion effector
HNAFNGMG_00656 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
HNAFNGMG_00657 1.1e-49
HNAFNGMG_00658 8.7e-60
HNAFNGMG_00659 5.9e-55
HNAFNGMG_00660 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAFNGMG_00661 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
HNAFNGMG_00662 9.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
HNAFNGMG_00663 1.6e-61 smtB K Transcriptional regulator
HNAFNGMG_00664 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HNAFNGMG_00666 1e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HNAFNGMG_00667 2.5e-130 S Domain of unknown function (DUF4336)
HNAFNGMG_00668 1e-202 yeaN P transporter
HNAFNGMG_00669 2.1e-149 yitS S EDD domain protein, DegV family
HNAFNGMG_00670 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
HNAFNGMG_00671 2.7e-109 cutC P Participates in the control of copper homeostasis
HNAFNGMG_00673 5.4e-21 S Domain of unknown function (DUF4767)
HNAFNGMG_00674 5.5e-253 norB P Major facilitator superfamily
HNAFNGMG_00675 6.3e-91 tetR K transcriptional regulator
HNAFNGMG_00676 2.3e-148 S Domain of unknown function (DUF4300)
HNAFNGMG_00677 4.4e-119 V CAAX protease self-immunity
HNAFNGMG_00678 1.4e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HNAFNGMG_00679 4.9e-134 fecE 3.6.3.34 HP ABC transporter
HNAFNGMG_00680 8.5e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HNAFNGMG_00681 1e-122 ybbA S Putative esterase
HNAFNGMG_00682 4.3e-158 yegS 2.7.1.107 I Diacylglycerol kinase
HNAFNGMG_00683 2.8e-172 S Domain of unknown function (DUF389)
HNAFNGMG_00684 5.5e-31 S Membrane
HNAFNGMG_00685 2.9e-09 S CsbD-like
HNAFNGMG_00686 9.5e-173 pdhD 1.8.1.4 C Dehydrogenase
HNAFNGMG_00687 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
HNAFNGMG_00688 1.3e-174 acoB C dehydrogenase E1 component
HNAFNGMG_00689 4.7e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNAFNGMG_00690 4.2e-80 Q Methyltransferase domain
HNAFNGMG_00691 3.4e-74 K TetR family transcriptional regulator
HNAFNGMG_00692 5.8e-49
HNAFNGMG_00693 1.7e-126 V CAAX protease self-immunity
HNAFNGMG_00694 2.6e-10
HNAFNGMG_00695 6.5e-19 M Bacterial lipoprotein
HNAFNGMG_00696 2.4e-60 S Protein of unknown function (DUF1722)
HNAFNGMG_00697 2.4e-62 yqeB S Pyrimidine dimer DNA glycosylase
HNAFNGMG_00699 2.1e-50
HNAFNGMG_00700 1e-89 S CAAX protease self-immunity
HNAFNGMG_00701 3.1e-113 estA E GDSL-like Lipase/Acylhydrolase
HNAFNGMG_00702 3.8e-100
HNAFNGMG_00703 4.3e-276 sulP P Sulfate permease and related transporters (MFS superfamily)
HNAFNGMG_00704 8.4e-148 ycgQ S TIGR03943 family
HNAFNGMG_00705 3.5e-155 XK27_03015 S permease
HNAFNGMG_00707 0.0 yhgF K Transcriptional accessory protein
HNAFNGMG_00708 3.9e-83 ydcK S Belongs to the SprT family
HNAFNGMG_00709 2.9e-41 pspC KT PspC domain
HNAFNGMG_00710 5.4e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HNAFNGMG_00711 9.9e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HNAFNGMG_00712 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HNAFNGMG_00713 3e-67 ytxH S General stress protein
HNAFNGMG_00715 1.5e-177 yegQ O Peptidase U32
HNAFNGMG_00716 8.3e-251 yegQ O Peptidase U32
HNAFNGMG_00717 1.1e-87 bioY S biotin synthase
HNAFNGMG_00719 1.1e-33 XK27_12190 S protein conserved in bacteria
HNAFNGMG_00720 2.8e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HNAFNGMG_00721 1.5e-12
HNAFNGMG_00722 2.5e-65 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
HNAFNGMG_00723 0.0 L helicase
HNAFNGMG_00724 5.3e-97 K MerR, DNA binding
HNAFNGMG_00725 6.2e-180 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
HNAFNGMG_00726 2.5e-15
HNAFNGMG_00727 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HNAFNGMG_00728 2.4e-136 M LysM domain
HNAFNGMG_00729 8.4e-23
HNAFNGMG_00730 5.2e-175 S hydrolase
HNAFNGMG_00732 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HNAFNGMG_00733 8.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HNAFNGMG_00734 9.4e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HNAFNGMG_00735 3e-26 P Hemerythrin HHE cation binding domain protein
HNAFNGMG_00736 5.8e-92 5.2.1.8 G hydrolase
HNAFNGMG_00737 2e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HNAFNGMG_00738 4.3e-198 MA20_36090 S Protein of unknown function (DUF2974)
HNAFNGMG_00739 3.8e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAFNGMG_00740 4.4e-45 S Phage derived protein Gp49-like (DUF891)
HNAFNGMG_00741 3.8e-45 K Helix-turn-helix domain
HNAFNGMG_00742 4.7e-41 S Nucleotide pyrophosphohydrolase
HNAFNGMG_00743 1.2e-188 L Uncharacterized conserved protein (DUF2075)
HNAFNGMG_00744 2e-134 S double-stranded DNA endodeoxyribonuclease activity
HNAFNGMG_00745 0.0 2.4.1.21 GT5 M Right handed beta helix region
HNAFNGMG_00746 5.3e-176 spd F DNA RNA non-specific endonuclease
HNAFNGMG_00747 7.7e-92 lemA S LemA family
HNAFNGMG_00748 1.3e-133 htpX O Belongs to the peptidase M48B family
HNAFNGMG_00749 5e-119 sirR K iron dependent repressor
HNAFNGMG_00750 4e-170 sitA P Belongs to the bacterial solute-binding protein 9 family
HNAFNGMG_00751 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HNAFNGMG_00752 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
HNAFNGMG_00753 4.7e-74 S Psort location CytoplasmicMembrane, score
HNAFNGMG_00754 8.1e-64 S Domain of unknown function (DUF4430)
HNAFNGMG_00755 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HNAFNGMG_00756 1.3e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HNAFNGMG_00757 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HNAFNGMG_00758 2.9e-164 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HNAFNGMG_00759 1.8e-100 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HNAFNGMG_00760 9e-79 dps P Belongs to the Dps family
HNAFNGMG_00761 1.7e-78 perR P Belongs to the Fur family
HNAFNGMG_00762 4.2e-27 yqgQ S protein conserved in bacteria
HNAFNGMG_00763 1.1e-175 glk 2.7.1.2 G Glucokinase
HNAFNGMG_00764 0.0 typA T GTP-binding protein TypA
HNAFNGMG_00766 5.7e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HNAFNGMG_00767 4.4e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HNAFNGMG_00768 4.8e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HNAFNGMG_00769 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HNAFNGMG_00770 8.6e-235 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HNAFNGMG_00771 1.2e-118 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HNAFNGMG_00772 3.4e-90 sepF D cell septum assembly
HNAFNGMG_00773 1.7e-30 yggT D integral membrane protein
HNAFNGMG_00774 1e-137 ylmH S conserved protein, contains S4-like domain
HNAFNGMG_00775 8.4e-138 divIVA D Cell division initiation protein
HNAFNGMG_00776 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HNAFNGMG_00777 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNAFNGMG_00778 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HNAFNGMG_00779 2.2e-34 nrdH O Glutaredoxin
HNAFNGMG_00780 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HNAFNGMG_00781 6.9e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
HNAFNGMG_00782 1.4e-217 icd 1.1.1.42 C Isocitrate dehydrogenase
HNAFNGMG_00783 3e-38 ptsH G phosphocarrier protein Hpr
HNAFNGMG_00784 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HNAFNGMG_00785 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HNAFNGMG_00786 3.9e-161 XK27_05670 S Putative esterase
HNAFNGMG_00787 2.7e-153 XK27_05675 S Esterase
HNAFNGMG_00788 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
HNAFNGMG_00789 6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HNAFNGMG_00790 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HNAFNGMG_00791 0.0 uup S abc transporter atp-binding protein
HNAFNGMG_00792 2.7e-39 MA20_06245 S yiaA/B two helix domain
HNAFNGMG_00793 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
HNAFNGMG_00794 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNAFNGMG_00795 6.2e-148 cobQ S glutamine amidotransferase
HNAFNGMG_00796 5.4e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HNAFNGMG_00797 1.1e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HNAFNGMG_00798 1.1e-162 ybbR S Protein conserved in bacteria
HNAFNGMG_00799 2.8e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HNAFNGMG_00800 1.3e-64 gtrA S GtrA-like protein
HNAFNGMG_00801 1.1e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
HNAFNGMG_00802 1.9e-141 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HNAFNGMG_00803 9.7e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
HNAFNGMG_00804 3.3e-200 yurR 1.4.5.1 E oxidoreductase
HNAFNGMG_00805 5.6e-258 S phospholipase Carboxylesterase
HNAFNGMG_00806 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HNAFNGMG_00807 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HNAFNGMG_00808 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HNAFNGMG_00810 8.4e-30 KT response to antibiotic
HNAFNGMG_00811 5.9e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
HNAFNGMG_00812 2.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HNAFNGMG_00813 2.1e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HNAFNGMG_00814 9.3e-118 ylfI S tigr01906
HNAFNGMG_00815 2.1e-137 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HNAFNGMG_00816 1.6e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HNAFNGMG_00817 8.3e-61 XK27_08085
HNAFNGMG_00818 5.7e-189 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HNAFNGMG_00819 4.8e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HNAFNGMG_00820 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HNAFNGMG_00821 1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HNAFNGMG_00822 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HNAFNGMG_00823 3.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HNAFNGMG_00824 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HNAFNGMG_00825 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HNAFNGMG_00826 1.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HNAFNGMG_00827 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HNAFNGMG_00829 3.8e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
HNAFNGMG_00830 6.3e-145 P molecular chaperone
HNAFNGMG_00831 1.9e-98 S Carbohydrate-binding domain-containing protein Cthe_2159
HNAFNGMG_00832 3e-171 XK27_08075 M glycosyl transferase family 2
HNAFNGMG_00833 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_00834 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_00835 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_00836 3.2e-227 rodA D Belongs to the SEDS family
HNAFNGMG_00837 5.1e-243 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HNAFNGMG_00838 1.4e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HNAFNGMG_00839 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HNAFNGMG_00840 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAFNGMG_00841 7.5e-21 Q Methyltransferase domain
HNAFNGMG_00842 3.7e-64 GnaT 2.5.1.16 K acetyltransferase
HNAFNGMG_00843 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HNAFNGMG_00844 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HNAFNGMG_00845 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HNAFNGMG_00846 1.3e-125 dnaD
HNAFNGMG_00847 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HNAFNGMG_00849 1.4e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNAFNGMG_00850 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HNAFNGMG_00851 3.4e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HNAFNGMG_00852 4.7e-146 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HNAFNGMG_00853 7.5e-74 argR K Regulates arginine biosynthesis genes
HNAFNGMG_00854 2.9e-296 recN L May be involved in recombinational repair of damaged DNA
HNAFNGMG_00855 2e-144 DegV S DegV family
HNAFNGMG_00856 1.2e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
HNAFNGMG_00857 3.4e-95 ypmS S Protein conserved in bacteria
HNAFNGMG_00858 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HNAFNGMG_00860 4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HNAFNGMG_00861 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HNAFNGMG_00862 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HNAFNGMG_00863 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HNAFNGMG_00864 2.8e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNAFNGMG_00865 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HNAFNGMG_00866 0.0 dnaE 2.7.7.7 L DNA polymerase
HNAFNGMG_00867 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HNAFNGMG_00868 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HNAFNGMG_00869 4.6e-14 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_00870 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_00871 1.7e-18 S Domain of unknown function (DUF4649)
HNAFNGMG_00872 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
HNAFNGMG_00873 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HNAFNGMG_00874 8.9e-136 XK27_08845 S abc transporter atp-binding protein
HNAFNGMG_00875 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNAFNGMG_00876 4e-147 estA CE1 S Esterase
HNAFNGMG_00877 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HNAFNGMG_00878 3.4e-19 XK27_08880
HNAFNGMG_00879 3.9e-75 fld C Flavodoxin
HNAFNGMG_00880 2.3e-279 clcA P Chloride transporter, ClC family
HNAFNGMG_00881 4.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HNAFNGMG_00882 4.3e-212 XK27_05110 P Chloride transporter ClC family
HNAFNGMG_00883 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HNAFNGMG_00885 4e-198 S Phage integrase family
HNAFNGMG_00886 1.5e-27 E Pfam:DUF955
HNAFNGMG_00888 1.4e-36
HNAFNGMG_00889 1.7e-44 S sequence-specific DNA binding
HNAFNGMG_00893 1.1e-07 K Cro/C1-type HTH DNA-binding domain
HNAFNGMG_00894 3.7e-115 S DNA binding
HNAFNGMG_00897 1.9e-67 M Pilin isopeptide linkage domain protein
HNAFNGMG_00898 3.4e-45 dnaD L Replication initiation and membrane attachment
HNAFNGMG_00899 4.7e-132 S IstB-like ATP binding protein
HNAFNGMG_00901 5.5e-78 recT L Recombinational DNA repair protein (RecE pathway)
HNAFNGMG_00902 2.5e-99 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HNAFNGMG_00903 1.7e-56 S Single-strand binding protein family
HNAFNGMG_00904 2.7e-33 L NUMOD4 motif
HNAFNGMG_00905 5.9e-74 S magnesium ion binding
HNAFNGMG_00907 3.8e-10
HNAFNGMG_00911 5e-29 S Protein of unknown function (DUF1642)
HNAFNGMG_00912 4.7e-46 S sequence-specific DNA binding
HNAFNGMG_00914 1.5e-22 S YopX protein
HNAFNGMG_00916 5e-13 S Protein of unknown function (DUF1492)
HNAFNGMG_00917 5.8e-86 S peptidase activity
HNAFNGMG_00918 2.5e-67 S Phage terminase, small subunit
HNAFNGMG_00919 0.0 S Phage Terminase
HNAFNGMG_00921 6.6e-199 S Phage portal protein
HNAFNGMG_00922 1.3e-114 S Clp protease
HNAFNGMG_00923 4.4e-206 S peptidase activity
HNAFNGMG_00924 7.7e-49 S Phage gp6-like head-tail connector protein
HNAFNGMG_00925 7.5e-61 S Phage head-tail joining protein
HNAFNGMG_00926 6e-65 S exonuclease activity
HNAFNGMG_00927 2.6e-56 S Protein of unknown function (DUF806)
HNAFNGMG_00928 2.5e-96 S Pfam:Phage_TTP_1
HNAFNGMG_00930 0.0 S peptidoglycan catabolic process
HNAFNGMG_00931 4.9e-229 S Phage tail protein
HNAFNGMG_00932 0.0 S peptidoglycan catabolic process
HNAFNGMG_00933 5.5e-180
HNAFNGMG_00934 1e-11
HNAFNGMG_00935 1.1e-42
HNAFNGMG_00936 4.7e-26 hol S Holin, phage phi LC3 family
HNAFNGMG_00937 5.5e-08
HNAFNGMG_00940 2.3e-81 S peptidoglycan catabolic process
HNAFNGMG_00942 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
HNAFNGMG_00943 7.9e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HNAFNGMG_00944 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HNAFNGMG_00945 2.4e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HNAFNGMG_00946 5.3e-170 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HNAFNGMG_00947 3.3e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HNAFNGMG_00948 2.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HNAFNGMG_00949 1e-131
HNAFNGMG_00951 7.4e-247 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
HNAFNGMG_00952 1e-193 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HNAFNGMG_00953 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNAFNGMG_00954 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
HNAFNGMG_00955 2e-155 endA F DNA RNA non-specific endonuclease
HNAFNGMG_00956 5e-111 tcyB_2 P ABC transporter (permease)
HNAFNGMG_00957 1.9e-116 gltJ P ABC transporter (Permease
HNAFNGMG_00958 1.1e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNAFNGMG_00959 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_00960 5e-111 tcyB_2 P ABC transporter (permease)
HNAFNGMG_00961 1.9e-116 gltJ P ABC transporter (Permease
HNAFNGMG_00962 1.8e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNAFNGMG_00963 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_00964 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNAFNGMG_00965 2.2e-230 vicK 2.7.13.3 T Histidine kinase
HNAFNGMG_00966 5.1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HNAFNGMG_00967 1.9e-56 S Protein of unknown function (DUF454)
HNAFNGMG_00968 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HNAFNGMG_00969 2.7e-146 yidA S hydrolases of the HAD superfamily
HNAFNGMG_00970 9.1e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HNAFNGMG_00971 5.3e-68 ywiB S Domain of unknown function (DUF1934)
HNAFNGMG_00972 0.0 pacL 3.6.3.8 P cation transport ATPase
HNAFNGMG_00973 3.6e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HNAFNGMG_00974 1.8e-153 yjjH S Calcineurin-like phosphoesterase
HNAFNGMG_00975 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HNAFNGMG_00976 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HNAFNGMG_00977 3.2e-124 ftsE D cell division ATP-binding protein FtsE
HNAFNGMG_00978 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HNAFNGMG_00979 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNAFNGMG_00980 4e-175 yubA S permease
HNAFNGMG_00981 1.9e-220 G COG0457 FOG TPR repeat
HNAFNGMG_00982 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HNAFNGMG_00983 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HNAFNGMG_00984 2.2e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HNAFNGMG_00985 1.2e-85 ebsA S Family of unknown function (DUF5322)
HNAFNGMG_00986 9.4e-17 M LysM domain
HNAFNGMG_00987 3.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HNAFNGMG_00988 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HNAFNGMG_00989 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HNAFNGMG_00990 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HNAFNGMG_00991 1.1e-75 XK27_03610 K Gnat family
HNAFNGMG_00992 1.9e-89 yybC
HNAFNGMG_00993 1.4e-221 L the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_00994 4.1e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HNAFNGMG_00995 5e-273 pepV 3.5.1.18 E Dipeptidase
HNAFNGMG_00996 2e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
HNAFNGMG_00997 7.1e-226 V Glucan-binding protein C
HNAFNGMG_00998 2.1e-252 V Glucan-binding protein C
HNAFNGMG_00999 4e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HNAFNGMG_01000 6e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HNAFNGMG_01001 1.8e-85 S Protein of unknown function (DUF1697)
HNAFNGMG_01002 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HNAFNGMG_01003 2.4e-50 S LemA family
HNAFNGMG_01004 3.7e-163 clcA_2 P chloride
HNAFNGMG_01005 5.5e-98 yfeJ 6.3.5.2 F glutamine amidotransferase
HNAFNGMG_01006 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HNAFNGMG_01007 1e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HNAFNGMG_01008 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HNAFNGMG_01009 2.6e-110 cps4C M biosynthesis protein
HNAFNGMG_01010 3.4e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
HNAFNGMG_01011 4.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HNAFNGMG_01012 1.6e-221 rgpAc GT4 M group 1 family protein
HNAFNGMG_01013 1.8e-212 wcoF M Glycosyltransferase, group 1 family protein
HNAFNGMG_01014 1.3e-187 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
HNAFNGMG_01015 6.6e-116 Z012_10770 M Domain of unknown function (DUF1919)
HNAFNGMG_01016 1.1e-138 M Glycosyltransferase, group 2 family protein
HNAFNGMG_01017 8.6e-155 M Glycosyltransferase like family 2
HNAFNGMG_01018 6.3e-173
HNAFNGMG_01019 1.3e-244 epsU S Polysaccharide biosynthesis protein
HNAFNGMG_01020 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
HNAFNGMG_01021 3e-182 wbbI M transferase activity, transferring glycosyl groups
HNAFNGMG_01023 3.4e-149 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HNAFNGMG_01024 5e-105 pgm G Belongs to the phosphoglycerate mutase family
HNAFNGMG_01025 4.5e-106 G Belongs to the phosphoglycerate mutase family
HNAFNGMG_01026 7.1e-104 G Belongs to the phosphoglycerate mutase family
HNAFNGMG_01027 4.4e-195 S hmm pf01594
HNAFNGMG_01028 8.9e-286 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNAFNGMG_01029 4.1e-38 S granule-associated protein
HNAFNGMG_01030 2e-278 S unusual protein kinase
HNAFNGMG_01031 6.5e-100 estA E Lysophospholipase L1 and related esterases
HNAFNGMG_01032 6.9e-153 rssA S Phospholipase, patatin family
HNAFNGMG_01033 5.8e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HNAFNGMG_01034 2.1e-211 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HNAFNGMG_01035 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HNAFNGMG_01036 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HNAFNGMG_01037 0.0 S the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_01038 9.3e-226 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01039 3e-197 hpk9 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01040 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HNAFNGMG_01041 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HNAFNGMG_01042 4.9e-217 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HNAFNGMG_01043 0.0 lpdA 1.8.1.4 C Dehydrogenase
HNAFNGMG_01044 0.0 3.5.1.28 NU amidase activity
HNAFNGMG_01045 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
HNAFNGMG_01046 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HNAFNGMG_01047 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
HNAFNGMG_01048 1.1e-231 ycdB P peroxidase
HNAFNGMG_01049 1.6e-286 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HNAFNGMG_01050 1.9e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HNAFNGMG_01051 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HNAFNGMG_01052 4.7e-213 msmX P Belongs to the ABC transporter superfamily
HNAFNGMG_01053 8.3e-151 malG P ABC transporter (Permease
HNAFNGMG_01054 5.7e-250 malF P ABC transporter (Permease
HNAFNGMG_01055 9.6e-228 malX G ABC transporter
HNAFNGMG_01056 1.6e-172 malR K Transcriptional regulator
HNAFNGMG_01057 1.2e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HNAFNGMG_01058 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HNAFNGMG_01059 1.2e-38
HNAFNGMG_01060 2.6e-183 lplA 6.3.1.20 H Lipoate-protein ligase
HNAFNGMG_01061 2.5e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HNAFNGMG_01062 0.0 pepN 3.4.11.2 E aminopeptidase
HNAFNGMG_01063 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HNAFNGMG_01064 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNAFNGMG_01065 3.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HNAFNGMG_01066 1.2e-155 pstA P phosphate transport system permease
HNAFNGMG_01067 7.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HNAFNGMG_01068 4.5e-155 pstS P phosphate
HNAFNGMG_01069 1.5e-244 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HNAFNGMG_01070 3.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HNAFNGMG_01071 1e-44 yktA S Belongs to the UPF0223 family
HNAFNGMG_01072 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HNAFNGMG_01073 7.4e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HNAFNGMG_01074 2.1e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HNAFNGMG_01075 1.5e-234 XK27_04775 S hemerythrin HHE cation binding domain
HNAFNGMG_01076 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
HNAFNGMG_01077 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HNAFNGMG_01078 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HNAFNGMG_01079 4.7e-137 S haloacid dehalogenase-like hydrolase
HNAFNGMG_01080 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
HNAFNGMG_01081 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HNAFNGMG_01082 2.4e-240 agcS E (Alanine) symporter
HNAFNGMG_01083 1.8e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HNAFNGMG_01084 1.3e-171 bglC K Transcriptional regulator
HNAFNGMG_01085 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HNAFNGMG_01086 9.3e-81 yecS P ABC transporter (Permease
HNAFNGMG_01087 1.8e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
HNAFNGMG_01088 4.7e-242 nylA 3.5.1.4 J Belongs to the amidase family
HNAFNGMG_01089 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HNAFNGMG_01090 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HNAFNGMG_01092 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HNAFNGMG_01093 2.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HNAFNGMG_01094 6.1e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HNAFNGMG_01095 8e-135 S TraX protein
HNAFNGMG_01096 5.2e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HNAFNGMG_01097 2.4e-260 S Psort location CytoplasmicMembrane, score
HNAFNGMG_01098 1.1e-229 dinF V Mate efflux family protein
HNAFNGMG_01099 6e-177 yclQ P ABC-type enterochelin transport system, periplasmic component
HNAFNGMG_01100 0.0 V Type III restriction enzyme, res subunit
HNAFNGMG_01101 1.2e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HNAFNGMG_01102 3.5e-140 2.4.2.3 F Phosphorylase superfamily
HNAFNGMG_01103 1.5e-109 K Bacterial regulatory proteins, tetR family
HNAFNGMG_01104 1.8e-177 ybhR V ABC transporter
HNAFNGMG_01105 3e-125 ybhF_2 V abc transporter atp-binding protein
HNAFNGMG_01108 4.9e-138 G protein with an alpha beta hydrolase fold
HNAFNGMG_01109 1.1e-85 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HNAFNGMG_01110 0.0 copA 3.6.3.54 P P-type ATPase
HNAFNGMG_01111 4.8e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HNAFNGMG_01112 1.4e-63 copY K Copper transport repressor, CopY TcrY family
HNAFNGMG_01113 1.9e-189 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HNAFNGMG_01114 6.7e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HNAFNGMG_01115 5.2e-151 czcD P cation diffusion facilitator family transporter
HNAFNGMG_01116 1e-99 K Transcriptional regulator, TetR family
HNAFNGMG_01117 1.6e-58 S Protein of unknown function with HXXEE motif
HNAFNGMG_01118 1.7e-38
HNAFNGMG_01119 2.1e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAFNGMG_01120 1.6e-154 I Alpha/beta hydrolase family
HNAFNGMG_01121 2.8e-177 1.1.1.1 C nadph quinone reductase
HNAFNGMG_01122 3.2e-66 K Transcriptional regulator
HNAFNGMG_01123 7e-62 pnuC H nicotinamide mononucleotide transporter
HNAFNGMG_01124 3.9e-150 cbiO2 P ABC transporter, ATP-binding protein
HNAFNGMG_01125 1.7e-156 P ATPase activity
HNAFNGMG_01126 4.4e-133 cbiQ P cobalt transport
HNAFNGMG_01127 4.8e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
HNAFNGMG_01128 1.5e-138 S Phenazine biosynthesis protein
HNAFNGMG_01129 5.7e-92 tetR K transcriptional regulator
HNAFNGMG_01130 7.3e-124 V abc transporter atp-binding protein
HNAFNGMG_01131 0.0 V ABC transporter (Permease
HNAFNGMG_01132 3.7e-35 L Integrase core domain protein
HNAFNGMG_01133 2e-109 magIII L Base excision DNA repair protein, HhH-GPD family
HNAFNGMG_01134 3.8e-263 proWX P ABC transporter
HNAFNGMG_01135 7e-130 proV E abc transporter atp-binding protein
HNAFNGMG_01136 8.6e-168 C alcohol dehydrogenase
HNAFNGMG_01137 2.2e-135 1.6.5.2 GM NmrA-like family
HNAFNGMG_01138 8.9e-67 mgrA K Transcriptional regulator, MarR family
HNAFNGMG_01139 8.8e-78 S Macro domain
HNAFNGMG_01140 2.7e-93 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HNAFNGMG_01141 2.6e-39 C Pyridoxamine 5'-phosphate oxidase
HNAFNGMG_01142 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HNAFNGMG_01143 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HNAFNGMG_01146 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HNAFNGMG_01148 8.2e-137 IQ Acetoin reductase
HNAFNGMG_01149 2.2e-45 pspE P Rhodanese-like protein
HNAFNGMG_01150 5.5e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HNAFNGMG_01151 1e-223 XK27_05470 E Methionine synthase
HNAFNGMG_01152 2.4e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HNAFNGMG_01153 3.2e-221 T PhoQ Sensor
HNAFNGMG_01154 5.1e-119 KT Transcriptional regulatory protein, C terminal
HNAFNGMG_01155 2.1e-146 S TraX protein
HNAFNGMG_01157 5.3e-53 V ABC-2 family transporter protein
HNAFNGMG_01158 2.1e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
HNAFNGMG_01159 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HNAFNGMG_01160 4.6e-157 dprA LU DNA protecting protein DprA
HNAFNGMG_01161 1.2e-152 GK ROK family
HNAFNGMG_01162 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNAFNGMG_01163 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HNAFNGMG_01164 2.4e-127 K DNA-binding helix-turn-helix protein
HNAFNGMG_01165 6e-83 niaR S small molecule binding protein (contains 3H domain)
HNAFNGMG_01166 2.1e-83
HNAFNGMG_01167 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HNAFNGMG_01168 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HNAFNGMG_01169 7.7e-126 gntR1 K transcriptional
HNAFNGMG_01170 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HNAFNGMG_01171 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HNAFNGMG_01172 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
HNAFNGMG_01173 1.8e-44
HNAFNGMG_01174 2.9e-50
HNAFNGMG_01175 6.7e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAFNGMG_01176 1.4e-153 aatB ET ABC transporter substrate-binding protein
HNAFNGMG_01177 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_01178 3.1e-105 artQ P ABC transporter (Permease
HNAFNGMG_01179 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
HNAFNGMG_01180 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HNAFNGMG_01181 2.9e-165 cpsY K Transcriptional regulator
HNAFNGMG_01182 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
HNAFNGMG_01183 1.6e-169 yeiH S Membrane
HNAFNGMG_01185 5.8e-09
HNAFNGMG_01186 1.8e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
HNAFNGMG_01187 2.5e-147 XK27_10720 D peptidase activity
HNAFNGMG_01188 4.3e-277 pepD E Dipeptidase
HNAFNGMG_01189 1.3e-160 whiA K May be required for sporulation
HNAFNGMG_01190 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HNAFNGMG_01191 5.5e-161 rapZ S Displays ATPase and GTPase activities
HNAFNGMG_01192 3.8e-134 yejC S cyclic nucleotide-binding protein
HNAFNGMG_01193 1.1e-201 D nuclear chromosome segregation
HNAFNGMG_01194 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HNAFNGMG_01195 7.9e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HNAFNGMG_01196 4.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
HNAFNGMG_01197 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HNAFNGMG_01198 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HNAFNGMG_01199 5.3e-18
HNAFNGMG_01200 1.9e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HNAFNGMG_01201 1.4e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HNAFNGMG_01202 6.6e-76 ypmB S Protein conserved in bacteria
HNAFNGMG_01203 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HNAFNGMG_01204 5.2e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HNAFNGMG_01205 8.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HNAFNGMG_01206 2.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
HNAFNGMG_01207 4.6e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HNAFNGMG_01208 1.8e-190 tcsA S membrane
HNAFNGMG_01209 8.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HNAFNGMG_01210 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HNAFNGMG_01211 1.1e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HNAFNGMG_01212 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
HNAFNGMG_01213 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HNAFNGMG_01214 1e-29 rpsT J Binds directly to 16S ribosomal RNA
HNAFNGMG_01215 1.7e-241 T PhoQ Sensor
HNAFNGMG_01216 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HNAFNGMG_01217 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HNAFNGMG_01218 3.5e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HNAFNGMG_01219 8.2e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HNAFNGMG_01220 4.1e-93 panT S ECF transporter, substrate-specific component
HNAFNGMG_01221 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HNAFNGMG_01222 2.2e-162 metF 1.5.1.20 E reductase
HNAFNGMG_01223 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HNAFNGMG_01225 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HNAFNGMG_01226 0.0 3.6.3.8 P cation transport ATPase
HNAFNGMG_01227 1.2e-238 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HNAFNGMG_01228 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNAFNGMG_01229 4.7e-235 dltB M Membrane protein involved in D-alanine export
HNAFNGMG_01230 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HNAFNGMG_01231 0.0 XK27_10035 V abc transporter atp-binding protein
HNAFNGMG_01232 5.9e-292 yfiB1 V abc transporter atp-binding protein
HNAFNGMG_01233 1.4e-99 pvaA M lytic transglycosylase activity
HNAFNGMG_01234 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HNAFNGMG_01235 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HNAFNGMG_01236 1.9e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HNAFNGMG_01237 1.5e-139 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HNAFNGMG_01238 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HNAFNGMG_01239 1.9e-109 tdk 2.7.1.21 F thymidine kinase
HNAFNGMG_01240 1.3e-182 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HNAFNGMG_01241 3.5e-151 gst O Glutathione S-transferase
HNAFNGMG_01242 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HNAFNGMG_01243 3.5e-166 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HNAFNGMG_01244 4.4e-45 rpmE2 J 50S ribosomal protein L31
HNAFNGMG_01245 1.3e-227 mntH P Mn2 and Fe2 transporters of the NRAMP family
HNAFNGMG_01246 7.9e-161 ypuA S secreted protein
HNAFNGMG_01247 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HNAFNGMG_01248 3e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HNAFNGMG_01249 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNAFNGMG_01250 3.8e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HNAFNGMG_01251 1.9e-88 L COG1943 Transposase and inactivated derivatives
HNAFNGMG_01252 7.8e-255 noxE P NADH oxidase
HNAFNGMG_01253 2.1e-293 yfmM S abc transporter atp-binding protein
HNAFNGMG_01254 3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HNAFNGMG_01255 2.6e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HNAFNGMG_01256 6.3e-85 S ECF-type riboflavin transporter, S component
HNAFNGMG_01258 6.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HNAFNGMG_01259 1.2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HNAFNGMG_01261 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNAFNGMG_01262 6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNAFNGMG_01263 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HNAFNGMG_01264 3.8e-22 WQ51_00220 K Helix-turn-helix domain
HNAFNGMG_01265 6.3e-91 S Protein of unknown function (DUF3278)
HNAFNGMG_01266 0.0 smc D Required for chromosome condensation and partitioning
HNAFNGMG_01267 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HNAFNGMG_01268 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HNAFNGMG_01269 2.8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HNAFNGMG_01270 8.8e-124 alkD L DNA alkylation repair enzyme
HNAFNGMG_01271 3.1e-292 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNAFNGMG_01272 1.7e-90 pat 2.3.1.183 M acetyltransferase
HNAFNGMG_01273 7.9e-266 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HNAFNGMG_01274 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HNAFNGMG_01275 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HNAFNGMG_01276 1.5e-36 L RePlication protein
HNAFNGMG_01277 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HNAFNGMG_01278 6.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HNAFNGMG_01279 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
HNAFNGMG_01280 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
HNAFNGMG_01281 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
HNAFNGMG_01282 9.2e-167 L Integrase
HNAFNGMG_01283 3.5e-202 S Protein of unknown function DUF262
HNAFNGMG_01284 3.5e-151 S Protein of unknown function DUF262
HNAFNGMG_01285 4.5e-79 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HNAFNGMG_01286 4.2e-76 3.4.21.89 S RDD family
HNAFNGMG_01287 2.3e-122 K sequence-specific DNA binding
HNAFNGMG_01288 4.7e-146 V ABC transporter, ATP-binding protein
HNAFNGMG_01289 7.8e-81 S ABC-2 family transporter protein
HNAFNGMG_01290 1.8e-146 K sequence-specific DNA binding
HNAFNGMG_01291 2e-46
HNAFNGMG_01292 1.3e-88
HNAFNGMG_01293 2.3e-24
HNAFNGMG_01294 1.4e-139 S ABC-2 family transporter protein
HNAFNGMG_01295 6.9e-142 S ABC-2 family transporter protein
HNAFNGMG_01296 8e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
HNAFNGMG_01297 4.8e-80
HNAFNGMG_01298 9.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNAFNGMG_01299 5.5e-187 desK 2.7.13.3 T Histidine kinase
HNAFNGMG_01300 4e-133 yvfS V ABC-2 type transporter
HNAFNGMG_01301 4.2e-153 XK27_09825 V 'abc transporter, ATP-binding protein
HNAFNGMG_01304 2.5e-172 fabH 2.3.1.180 I synthase III
HNAFNGMG_01305 1.2e-238 6.2.1.30 H Coenzyme F390 synthetase
HNAFNGMG_01306 6.9e-150 gumP S Metallo-beta-lactamase superfamily
HNAFNGMG_01307 3.2e-178 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
HNAFNGMG_01308 1.5e-228 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
HNAFNGMG_01309 1.8e-107 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HNAFNGMG_01310 4.7e-197 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
HNAFNGMG_01311 3.1e-100
HNAFNGMG_01312 1.3e-208 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
HNAFNGMG_01314 1.8e-203 anK3 G response to abiotic stimulus
HNAFNGMG_01315 0.0 hscC O Belongs to the heat shock protein 70 family
HNAFNGMG_01316 9.6e-164 yocS S Transporter
HNAFNGMG_01317 1.5e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HNAFNGMG_01318 3.1e-117 yvfS V Transporter
HNAFNGMG_01319 4.1e-156 XK27_09825 V abc transporter atp-binding protein
HNAFNGMG_01320 1.1e-15 liaI KT membrane
HNAFNGMG_01321 2e-30 liaI KT membrane
HNAFNGMG_01322 6.1e-93 XK27_05000 S metal cluster binding
HNAFNGMG_01324 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HNAFNGMG_01325 1.9e-223 pbuX F xanthine permease
HNAFNGMG_01326 1.8e-243 norM V Multidrug efflux pump
HNAFNGMG_01328 1e-184 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HNAFNGMG_01329 3.6e-233 brnQ E Component of the transport system for branched-chain amino acids
HNAFNGMG_01330 5.1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
HNAFNGMG_01331 2e-58 S Protein of unknown function (DUF3290)
HNAFNGMG_01332 6e-101 S Protein of unknown function (DUF421)
HNAFNGMG_01333 5.9e-15 csbD K CsbD-like
HNAFNGMG_01334 2.9e-95 S Carbohydrate-binding domain-containing protein Cthe_2159
HNAFNGMG_01335 1.7e-27 S Carbohydrate-binding domain-containing protein Cthe_2159
HNAFNGMG_01336 7.5e-50 XK27_01300 P Protein conserved in bacteria
HNAFNGMG_01337 1.8e-222 yfnA E amino acid
HNAFNGMG_01338 0.0 S dextransucrase activity
HNAFNGMG_01339 2.5e-50 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HNAFNGMG_01340 1.5e-42 S Sugar efflux transporter for intercellular exchange
HNAFNGMG_01341 3e-204 P FtsX-like permease family
HNAFNGMG_01342 6e-123 V abc transporter atp-binding protein
HNAFNGMG_01343 1.1e-96 K WHG domain
HNAFNGMG_01344 7.5e-169 ydhF S Aldo keto reductase
HNAFNGMG_01345 4.9e-07 S Protein of unknown function (DUF3169)
HNAFNGMG_01346 2.5e-27 XK27_07105 K transcriptional
HNAFNGMG_01347 2.8e-35
HNAFNGMG_01348 8.7e-110 XK27_02070 S nitroreductase
HNAFNGMG_01349 2.4e-153 1.13.11.2 S glyoxalase
HNAFNGMG_01350 6.8e-75 ywnA K Transcriptional regulator
HNAFNGMG_01351 4.1e-153 E Alpha/beta hydrolase of unknown function (DUF915)
HNAFNGMG_01352 5.1e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HNAFNGMG_01353 2.4e-167 bcrA V abc transporter atp-binding protein
HNAFNGMG_01354 1.4e-128 S ABC-2 family transporter protein
HNAFNGMG_01355 1.5e-147 T PhoQ Sensor
HNAFNGMG_01356 1.9e-124 T Xre family transcriptional regulator
HNAFNGMG_01357 1.7e-108 drgA C nitroreductase
HNAFNGMG_01358 1.1e-103 yoaK S Protein of unknown function (DUF1275)
HNAFNGMG_01359 1.3e-38 DJ nuclease activity
HNAFNGMG_01360 5.5e-30 XK27_10490
HNAFNGMG_01361 8.6e-156 yvgN C reductase
HNAFNGMG_01362 3.2e-209 S Tetratricopeptide repeat
HNAFNGMG_01363 0.0 lacL 3.2.1.23 G -beta-galactosidase
HNAFNGMG_01364 0.0 lacS G transporter
HNAFNGMG_01365 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HNAFNGMG_01366 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HNAFNGMG_01367 9.8e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HNAFNGMG_01368 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HNAFNGMG_01369 3.2e-181 galR K Transcriptional regulator
HNAFNGMG_01370 1.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
HNAFNGMG_01371 3.8e-227 vncS 2.7.13.3 T Histidine kinase
HNAFNGMG_01372 5.7e-115 K Response regulator receiver domain protein
HNAFNGMG_01373 1.6e-239 vex3 V Efflux ABC transporter, permease protein
HNAFNGMG_01374 1e-108 vex2 V abc transporter atp-binding protein
HNAFNGMG_01375 4e-181 vex1 V Efflux ABC transporter, permease protein
HNAFNGMG_01376 8.6e-284 XK27_07020 S Belongs to the UPF0371 family
HNAFNGMG_01378 4.3e-200 gldA 1.1.1.6 C glycerol dehydrogenase
HNAFNGMG_01379 1.2e-177 XK27_10475 S oxidoreductase
HNAFNGMG_01380 6.3e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
HNAFNGMG_01381 4.5e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
HNAFNGMG_01382 1.7e-179 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
HNAFNGMG_01383 7e-226 thrE K Psort location CytoplasmicMembrane, score
HNAFNGMG_01384 2.4e-34 S Immunity protein 41
HNAFNGMG_01385 0.0 pepO 3.4.24.71 O Peptidase family M13
HNAFNGMG_01386 9e-08 S Enterocin A Immunity
HNAFNGMG_01387 6.3e-193 mccF V LD-carboxypeptidase
HNAFNGMG_01388 1.8e-14 S integral membrane protein
HNAFNGMG_01389 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
HNAFNGMG_01390 1.7e-107 yhfC S Putative membrane peptidase family (DUF2324)
HNAFNGMG_01392 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_01394 1.8e-244 S dextransucrase activity
HNAFNGMG_01395 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_01396 0.0 S dextransucrase activity
HNAFNGMG_01397 0.0 S dextransucrase activity
HNAFNGMG_01398 0.0 S dextransucrase activity
HNAFNGMG_01399 4.7e-88 M Putative cell wall binding repeat
HNAFNGMG_01400 0.0 S dextransucrase activity
HNAFNGMG_01401 6.8e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HNAFNGMG_01402 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HNAFNGMG_01403 0.0 M Putative cell wall binding repeat
HNAFNGMG_01404 0.0 S dextransucrase activity
HNAFNGMG_01405 0.0 M Putative cell wall binding repeat
HNAFNGMG_01406 3.4e-224 S dextransucrase activity
HNAFNGMG_01408 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HNAFNGMG_01409 3.1e-162 mleP S auxin efflux carrier
HNAFNGMG_01410 2.5e-308 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
HNAFNGMG_01411 2.7e-47 K Helix-turn-helix
HNAFNGMG_01412 1.5e-118 mleR K malolactic fermentation system
HNAFNGMG_01413 2.3e-131 XK27_00785 S CAAX protease self-immunity
HNAFNGMG_01414 3e-238 EGP Major facilitator Superfamily
HNAFNGMG_01415 6.2e-67 rmaI K Transcriptional regulator, MarR family
HNAFNGMG_01416 1.1e-91 maa 2.3.1.79 GK Maltose O-acetyltransferase
HNAFNGMG_01417 8.2e-128 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HNAFNGMG_01418 0.0 3.5.1.28 M domain protein
HNAFNGMG_01419 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HNAFNGMG_01420 3.2e-24
HNAFNGMG_01424 1.3e-77 sraP UW Hep Hag repeat protein
HNAFNGMG_01425 6e-276 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
HNAFNGMG_01427 5.4e-189 nss M transferase activity, transferring glycosyl groups
HNAFNGMG_01428 3.6e-16 S Accessory secretory protein Sec, Asp5
HNAFNGMG_01429 2.6e-17 S Accessory secretory protein Sec Asp4
HNAFNGMG_01430 6.7e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HNAFNGMG_01431 1.3e-279 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HNAFNGMG_01432 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNAFNGMG_01433 7.2e-77 asp3 S Accessory Sec system protein Asp3
HNAFNGMG_01434 2.2e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HNAFNGMG_01435 3.2e-289 asp1 S Accessory Sec system protein Asp1
HNAFNGMG_01436 4.7e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HNAFNGMG_01437 0.0 M family 8
HNAFNGMG_01439 6.6e-18 S PFAM Uncharacterised protein family (UPF0153)
HNAFNGMG_01440 1.1e-142
HNAFNGMG_01441 0.0 sbcC L ATPase involved in DNA repair
HNAFNGMG_01442 3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HNAFNGMG_01443 0.0 GM domain, Protein
HNAFNGMG_01444 0.0 zmpB M signal peptide protein, YSIRK family
HNAFNGMG_01445 0.0 M domain protein
HNAFNGMG_01446 0.0 M domain protein
HNAFNGMG_01447 7.2e-131 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNAFNGMG_01448 0.0 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HNAFNGMG_01449 8.9e-12
HNAFNGMG_01450 2.8e-189 XK27_10075 S abc transporter atp-binding protein
HNAFNGMG_01451 0.0 V abc transporter atp-binding protein
HNAFNGMG_01452 9.4e-298 V abc transporter atp-binding protein
HNAFNGMG_01453 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HNAFNGMG_01457 1.7e-279 S Protein of unknown function (DUF3114)
HNAFNGMG_01458 1.5e-100 2.3.1.128 K Acetyltransferase GNAT Family
HNAFNGMG_01459 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HNAFNGMG_01460 2.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HNAFNGMG_01461 7e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
HNAFNGMG_01462 6.4e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HNAFNGMG_01463 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HNAFNGMG_01464 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HNAFNGMG_01465 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HNAFNGMG_01466 5.2e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HNAFNGMG_01467 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HNAFNGMG_01468 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HNAFNGMG_01471 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HNAFNGMG_01472 9.7e-170 vraS 2.7.13.3 T Histidine kinase
HNAFNGMG_01473 1.9e-116 yvqF S Membrane
HNAFNGMG_01474 2.1e-100 kcsA P Ion transport protein
HNAFNGMG_01475 2e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
HNAFNGMG_01476 2e-135 stp 3.1.3.16 T phosphatase
HNAFNGMG_01477 2e-239 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HNAFNGMG_01478 1.2e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HNAFNGMG_01479 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HNAFNGMG_01480 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HNAFNGMG_01481 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HNAFNGMG_01482 2.3e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HNAFNGMG_01483 4.3e-144 XK27_02985 S overlaps another CDS with the same product name
HNAFNGMG_01484 2.2e-145 supH S overlaps another CDS with the same product name
HNAFNGMG_01485 7.3e-62 yvoA_1 K Transcriptional
HNAFNGMG_01486 2.3e-117 skfE V abc transporter atp-binding protein
HNAFNGMG_01487 1.4e-128 V Psort location CytoplasmicMembrane, score
HNAFNGMG_01488 1e-170 oppF P Belongs to the ABC transporter superfamily
HNAFNGMG_01489 1.3e-201 oppD P Belongs to the ABC transporter superfamily
HNAFNGMG_01490 3.5e-166 amiD P ABC transporter (Permease
HNAFNGMG_01491 6.6e-276 amiC P ABC transporter (Permease
HNAFNGMG_01492 1.4e-310 amiA E ABC transporter, substrate-binding protein, family 5
HNAFNGMG_01493 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HNAFNGMG_01494 2.3e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HNAFNGMG_01495 2.7e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HNAFNGMG_01496 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HNAFNGMG_01497 3.9e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HNAFNGMG_01498 5.4e-101 yjbK S Adenylate cyclase
HNAFNGMG_01499 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HNAFNGMG_01500 2.3e-204 iscS 2.8.1.7 E Cysteine desulfurase
HNAFNGMG_01501 8.2e-60 XK27_04120 S Putative amino acid metabolism
HNAFNGMG_01502 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HNAFNGMG_01503 2.2e-128 puuD T peptidase C26
HNAFNGMG_01504 5.8e-118 radC E Belongs to the UPF0758 family
HNAFNGMG_01505 3.6e-168
HNAFNGMG_01506 6.9e-43 M Psort location CytoplasmicMembrane, score
HNAFNGMG_01507 1.6e-155 rfbJ M Glycosyl transferase family 2
HNAFNGMG_01508 0.0 rgpF M Rhamnan synthesis protein F
HNAFNGMG_01509 9.6e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HNAFNGMG_01510 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HNAFNGMG_01511 2e-141 rgpC GM Transport permease protein
HNAFNGMG_01512 1.5e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
HNAFNGMG_01513 2.5e-214 rgpA GT4 M Domain of unknown function (DUF1972)
HNAFNGMG_01514 1e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HNAFNGMG_01515 8e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HNAFNGMG_01516 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HNAFNGMG_01517 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HNAFNGMG_01518 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HNAFNGMG_01519 9.9e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HNAFNGMG_01520 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HNAFNGMG_01521 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
HNAFNGMG_01522 4e-201 arcT 2.6.1.1 E Aminotransferase
HNAFNGMG_01523 9.4e-136 ET Belongs to the bacterial solute-binding protein 3 family
HNAFNGMG_01524 3.2e-139 ET ABC transporter
HNAFNGMG_01525 1.8e-83 mutT 3.6.1.55 F Nudix family
HNAFNGMG_01526 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HNAFNGMG_01528 2.9e-160 S CAAX amino terminal protease family protein
HNAFNGMG_01529 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HNAFNGMG_01530 1.6e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_01531 1.7e-17 XK27_00735
HNAFNGMG_01532 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HNAFNGMG_01534 3.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HNAFNGMG_01535 9.8e-10 O ADP-ribosylglycohydrolase
HNAFNGMG_01536 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
HNAFNGMG_01537 1.7e-60 ycaO O OsmC-like protein
HNAFNGMG_01539 2.2e-149 EG Permeases of the drug metabolite transporter (DMT) superfamily
HNAFNGMG_01540 5e-08 N PFAM Uncharacterised protein family UPF0150
HNAFNGMG_01541 1.3e-111 serB 3.1.3.3 E phosphoserine phosphatase
HNAFNGMG_01542 9.3e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HNAFNGMG_01543 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HNAFNGMG_01544 5.1e-96 3.1.3.18 S IA, variant 1
HNAFNGMG_01545 9.4e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HNAFNGMG_01546 5.9e-56 lrgA S Effector of murein hydrolase LrgA
HNAFNGMG_01548 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HNAFNGMG_01549 7e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HNAFNGMG_01550 1.3e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HNAFNGMG_01551 3.1e-101 wecD M Acetyltransferase (GNAT) domain
HNAFNGMG_01552 1.5e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HNAFNGMG_01553 7.3e-153 GK ROK family
HNAFNGMG_01554 2e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
HNAFNGMG_01555 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
HNAFNGMG_01556 7e-203 potD P spermidine putrescine ABC transporter
HNAFNGMG_01557 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
HNAFNGMG_01558 1.5e-138 potB P ABC-type spermidine putrescine transport system, permease component I
HNAFNGMG_01559 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HNAFNGMG_01560 5.8e-166 murB 1.3.1.98 M cell wall formation
HNAFNGMG_01561 6.1e-77 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HNAFNGMG_01562 1.4e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HNAFNGMG_01563 9.9e-293 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HNAFNGMG_01564 1.5e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HNAFNGMG_01565 2.2e-99 folE 3.5.4.16 F gtp cyclohydrolase
HNAFNGMG_01566 0.0 ydaO E amino acid
HNAFNGMG_01567 1.1e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HNAFNGMG_01568 1.5e-36 ylqC L Belongs to the UPF0109 family
HNAFNGMG_01569 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HNAFNGMG_01571 8.7e-211 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01572 2.2e-123 agrA KT phosphorelay signal transduction system
HNAFNGMG_01573 8.3e-93 O protein import
HNAFNGMG_01575 2.1e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HNAFNGMG_01576 2.9e-17 yjdB S Domain of unknown function (DUF4767)
HNAFNGMG_01578 3.4e-157 xth 3.1.11.2 L exodeoxyribonuclease III
HNAFNGMG_01579 5.4e-70 S QueT transporter
HNAFNGMG_01581 3.8e-171 yfjR K regulation of single-species biofilm formation
HNAFNGMG_01583 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HNAFNGMG_01584 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HNAFNGMG_01585 1.1e-84 ccl S cog cog4708
HNAFNGMG_01586 8.4e-160 rbn E Belongs to the UPF0761 family
HNAFNGMG_01587 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HNAFNGMG_01588 2.5e-231 ytoI K transcriptional regulator containing CBS domains
HNAFNGMG_01589 5.3e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HNAFNGMG_01590 5.1e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HNAFNGMG_01591 0.0 comEC S Competence protein ComEC
HNAFNGMG_01592 2.2e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HNAFNGMG_01593 1.3e-142 plsC 2.3.1.51 I Acyltransferase
HNAFNGMG_01594 9.3e-159 nodB3 G deacetylase
HNAFNGMG_01595 1.8e-139 yabB 2.1.1.223 L Methyltransferase
HNAFNGMG_01596 1e-41 yazA L endonuclease containing a URI domain
HNAFNGMG_01597 1.7e-253 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HNAFNGMG_01598 7.6e-150 corA P CorA-like protein
HNAFNGMG_01599 9.6e-62 yjqA S Bacterial PH domain
HNAFNGMG_01600 2.4e-96 thiT S Thiamine transporter
HNAFNGMG_01601 2.6e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HNAFNGMG_01602 1.4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
HNAFNGMG_01603 1.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HNAFNGMG_01607 2.5e-155 cjaA ET ABC transporter substrate-binding protein
HNAFNGMG_01608 4.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_01609 3e-106 P ABC transporter (Permease
HNAFNGMG_01610 1.3e-114 papP P ABC transporter (Permease
HNAFNGMG_01611 1e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HNAFNGMG_01612 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HNAFNGMG_01613 0.0 copA 3.6.3.54 P P-type ATPase
HNAFNGMG_01614 7.2e-74 copY K negative regulation of transcription, DNA-templated
HNAFNGMG_01617 3.5e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HNAFNGMG_01618 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HNAFNGMG_01619 8.2e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HNAFNGMG_01620 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HNAFNGMG_01621 5.1e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HNAFNGMG_01622 5.2e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HNAFNGMG_01623 4.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HNAFNGMG_01624 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HNAFNGMG_01625 0.0 ctpE P E1-E2 ATPase
HNAFNGMG_01626 6.6e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HNAFNGMG_01628 1.9e-124 V abc transporter atp-binding protein
HNAFNGMG_01629 0.0 V ABC transporter (Permease
HNAFNGMG_01630 2.7e-49 K transcriptional regulator, MerR family
HNAFNGMG_01631 8.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
HNAFNGMG_01632 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HNAFNGMG_01633 6.8e-65 XK27_02560 S cog cog2151
HNAFNGMG_01634 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HNAFNGMG_01635 6.3e-221 ytfP S Flavoprotein
HNAFNGMG_01637 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HNAFNGMG_01638 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
HNAFNGMG_01639 6e-175 ecsB U Bacterial ABC transporter protein EcsB
HNAFNGMG_01640 8.4e-131 ecsA V abc transporter atp-binding protein
HNAFNGMG_01641 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HNAFNGMG_01642 4.2e-12
HNAFNGMG_01645 1.6e-103
HNAFNGMG_01647 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HNAFNGMG_01648 6.7e-43 yoeB S Addiction module toxin, Txe YoeB family
HNAFNGMG_01649 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HNAFNGMG_01650 4.5e-197 ylbM S Belongs to the UPF0348 family
HNAFNGMG_01651 2.2e-139 yqeM Q Methyltransferase domain protein
HNAFNGMG_01652 1e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HNAFNGMG_01653 1.1e-86 entB 3.5.1.19 Q Isochorismatase family
HNAFNGMG_01654 3.7e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HNAFNGMG_01655 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HNAFNGMG_01656 7.7e-49 yhbY J RNA-binding protein
HNAFNGMG_01657 6.6e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HNAFNGMG_01658 5.1e-98 yqeG S hydrolase of the HAD superfamily
HNAFNGMG_01659 5.3e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HNAFNGMG_01660 9.3e-65
HNAFNGMG_01661 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNAFNGMG_01662 1.3e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HNAFNGMG_01663 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HNAFNGMG_01664 9e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HNAFNGMG_01665 3.8e-187 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HNAFNGMG_01666 5.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
HNAFNGMG_01667 5.7e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HNAFNGMG_01668 2.2e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HNAFNGMG_01669 4.4e-100 pncA Q isochorismatase
HNAFNGMG_01670 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HNAFNGMG_01671 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HNAFNGMG_01672 9e-75 XK27_03180 T universal stress protein
HNAFNGMG_01674 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNAFNGMG_01675 1.4e-08 MU outer membrane autotransporter barrel domain protein
HNAFNGMG_01676 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HNAFNGMG_01677 1.2e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HNAFNGMG_01679 1.8e-24
HNAFNGMG_01681 0.0 yjcE P NhaP-type Na H and K H antiporters
HNAFNGMG_01682 1.5e-07
HNAFNGMG_01683 1.9e-95 ytqB J (SAM)-dependent
HNAFNGMG_01684 1.8e-181 yhcC S radical SAM protein
HNAFNGMG_01685 3.2e-187 ylbL T Belongs to the peptidase S16 family
HNAFNGMG_01686 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HNAFNGMG_01687 1.9e-92 rsmD 2.1.1.171 L Methyltransferase
HNAFNGMG_01688 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HNAFNGMG_01689 5e-10 S Protein of unknown function (DUF4059)
HNAFNGMG_01690 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
HNAFNGMG_01691 4e-162 yxeN P ABC transporter (Permease
HNAFNGMG_01692 1.1e-150 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HNAFNGMG_01693 8e-35
HNAFNGMG_01694 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAFNGMG_01695 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HNAFNGMG_01696 3.3e-141 cah 4.2.1.1 P carbonic anhydrase
HNAFNGMG_01697 5.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HNAFNGMG_01699 4.3e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HNAFNGMG_01700 1.4e-136 cppA E CppA N-terminal
HNAFNGMG_01701 2.1e-95 V CAAX protease self-immunity
HNAFNGMG_01702 4.7e-149 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HNAFNGMG_01703 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HNAFNGMG_01707 9.2e-44 spiA K sequence-specific DNA binding
HNAFNGMG_01714 0.0 mdlB V abc transporter atp-binding protein
HNAFNGMG_01715 0.0 mdlA V abc transporter atp-binding protein
HNAFNGMG_01718 1.3e-88 XK27_09885 V Glycopeptide antibiotics resistance protein
HNAFNGMG_01719 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HNAFNGMG_01720 5.7e-63 yutD J protein conserved in bacteria
HNAFNGMG_01721 8.5e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HNAFNGMG_01723 3.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HNAFNGMG_01724 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HNAFNGMG_01725 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HNAFNGMG_01726 4e-45 ftsL D cell division protein FtsL
HNAFNGMG_01727 2e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HNAFNGMG_01728 1.8e-94
HNAFNGMG_01731 2.2e-45 yhaI J Protein of unknown function (DUF805)
HNAFNGMG_01732 1.7e-56 yhaI J Protein of unknown function (DUF805)
HNAFNGMG_01733 5.4e-34 yhaI J Protein of unknown function (DUF805)
HNAFNGMG_01734 1e-58 yhaI J Membrane
HNAFNGMG_01735 4.2e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HNAFNGMG_01736 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HNAFNGMG_01737 5.2e-271 XK27_00765
HNAFNGMG_01738 8.9e-133 ecsA_2 V abc transporter atp-binding protein
HNAFNGMG_01739 3.1e-125 S Protein of unknown function (DUF554)
HNAFNGMG_01740 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HNAFNGMG_01741 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HNAFNGMG_01742 5.4e-232 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01743 1.1e-226 dcuS 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01744 1.5e-13
HNAFNGMG_01747 5.8e-146 V Psort location CytoplasmicMembrane, score
HNAFNGMG_01749 3e-298 O MreB/Mbl protein
HNAFNGMG_01750 2.6e-194 mccF V LD-carboxypeptidase
HNAFNGMG_01751 4e-43 S Sugar efflux transporter for intercellular exchange
HNAFNGMG_01752 5.6e-77 mccF V LD-carboxypeptidase
HNAFNGMG_01753 8.2e-120 liaI S membrane
HNAFNGMG_01754 1.3e-73 XK27_02470 K LytTr DNA-binding domain
HNAFNGMG_01755 1.5e-308 KT response to antibiotic
HNAFNGMG_01756 4.5e-118 yebC M Membrane
HNAFNGMG_01757 5.4e-256 XK27_03190 S hydrolases of the HAD superfamily
HNAFNGMG_01758 9.8e-169 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HNAFNGMG_01760 2.9e-31 yozG K Transcriptional regulator
HNAFNGMG_01764 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HNAFNGMG_01765 2.2e-191 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HNAFNGMG_01766 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HNAFNGMG_01767 1e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HNAFNGMG_01768 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HNAFNGMG_01769 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HNAFNGMG_01771 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HNAFNGMG_01772 7.2e-169 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HNAFNGMG_01773 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_01774 2.7e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HNAFNGMG_01775 1.1e-178 scrR K Transcriptional regulator
HNAFNGMG_01776 1.3e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HNAFNGMG_01777 1.7e-61 yqhY S protein conserved in bacteria
HNAFNGMG_01778 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HNAFNGMG_01779 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HNAFNGMG_01780 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HNAFNGMG_01782 1.8e-145 V 'abc transporter, ATP-binding protein
HNAFNGMG_01789 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HNAFNGMG_01790 1.2e-166 corA P COG0598 Mg2 and Co2 transporters
HNAFNGMG_01791 7.2e-121 XK27_01040 S Protein of unknown function (DUF1129)
HNAFNGMG_01793 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HNAFNGMG_01794 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNAFNGMG_01795 1.1e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HNAFNGMG_01796 2.1e-41 XK27_05745
HNAFNGMG_01797 1.1e-222 mutY L A G-specific adenine glycosylase
HNAFNGMG_01799 2.9e-09
HNAFNGMG_01800 1.6e-38
HNAFNGMG_01802 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HNAFNGMG_01803 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HNAFNGMG_01804 9.1e-90 cvpA S toxin biosynthetic process
HNAFNGMG_01805 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HNAFNGMG_01806 2.9e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HNAFNGMG_01807 4e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HNAFNGMG_01808 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HNAFNGMG_01809 2.2e-46 azlD S branched-chain amino acid
HNAFNGMG_01810 1.4e-111 azlC E AzlC protein
HNAFNGMG_01811 1.6e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HNAFNGMG_01812 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HNAFNGMG_01813 1.5e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HNAFNGMG_01814 1.5e-33 ykzG S Belongs to the UPF0356 family
HNAFNGMG_01815 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HNAFNGMG_01816 1.5e-115 pscB M CHAP domain protein
HNAFNGMG_01817 2e-263 glnA 6.3.1.2 E glutamine synthetase
HNAFNGMG_01818 8.5e-63 glnR K Transcriptional regulator
HNAFNGMG_01819 9.6e-86 S Fusaric acid resistance protein-like
HNAFNGMG_01820 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HNAFNGMG_01821 1.4e-114
HNAFNGMG_01822 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
HNAFNGMG_01823 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HNAFNGMG_01824 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HNAFNGMG_01825 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HNAFNGMG_01826 4e-142 purR 2.4.2.7 F operon repressor
HNAFNGMG_01827 1.7e-176 cbf S 3'-5' exoribonuclease yhaM
HNAFNGMG_01828 7.9e-169 rmuC S RmuC domain protein
HNAFNGMG_01829 4e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
HNAFNGMG_01830 1e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HNAFNGMG_01831 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HNAFNGMG_01833 3.5e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HNAFNGMG_01834 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HNAFNGMG_01835 1e-142 tatD L Hydrolase, tatd
HNAFNGMG_01836 1.7e-70 yccU S CoA-binding protein
HNAFNGMG_01837 5.3e-50 trxA O Belongs to the thioredoxin family
HNAFNGMG_01838 5.6e-141 S Macro domain protein
HNAFNGMG_01839 6.3e-59 L thioesterase
HNAFNGMG_01840 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
HNAFNGMG_01843 9.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HNAFNGMG_01844 3.4e-14 rpmH J Ribosomal protein L34
HNAFNGMG_01845 1.7e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HNAFNGMG_01846 4.5e-98 K Transcriptional regulator
HNAFNGMG_01847 3.2e-168 jag S RNA-binding protein
HNAFNGMG_01848 6.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HNAFNGMG_01849 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HNAFNGMG_01850 7.8e-263 argH 4.3.2.1 E Argininosuccinate lyase
HNAFNGMG_01851 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HNAFNGMG_01852 2.7e-129 fasA KT Response regulator of the LytR AlgR family
HNAFNGMG_01853 2.8e-225 fasC 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01854 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01855 3e-151 hpk9 2.7.13.3 T protein histidine kinase activity
HNAFNGMG_01856 4.8e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HNAFNGMG_01857 8.2e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HNAFNGMG_01858 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HNAFNGMG_01859 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HNAFNGMG_01860 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HNAFNGMG_01861 1.2e-50 S Protein of unknown function (DUF3397)
HNAFNGMG_01862 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HNAFNGMG_01863 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HNAFNGMG_01864 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HNAFNGMG_01865 1e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HNAFNGMG_01866 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HNAFNGMG_01867 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
HNAFNGMG_01868 7.9e-230 XK27_09615 C reductase
HNAFNGMG_01869 9.6e-141 fnt P Formate nitrite transporter
HNAFNGMG_01870 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
HNAFNGMG_01871 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HNAFNGMG_01872 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HNAFNGMG_01873 1.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HNAFNGMG_01874 2.9e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HNAFNGMG_01875 4.8e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HNAFNGMG_01876 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HNAFNGMG_01877 1.3e-126 S HAD hydrolase, family IA, variant
HNAFNGMG_01878 3.2e-158 rrmA 2.1.1.187 Q methyltransferase
HNAFNGMG_01882 1.1e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HNAFNGMG_01883 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HNAFNGMG_01884 8.3e-37 yeeD O sulfur carrier activity
HNAFNGMG_01885 6.1e-188 yeeE S Sulphur transport
HNAFNGMG_01886 1.9e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HNAFNGMG_01887 1.3e-08 S NTF2 fold immunity protein
HNAFNGMG_01888 2.3e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HNAFNGMG_01889 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
HNAFNGMG_01890 5.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HNAFNGMG_01891 6.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HNAFNGMG_01892 2.7e-112 S CAAX amino terminal protease family protein
HNAFNGMG_01894 2.5e-110 V CAAX protease self-immunity
HNAFNGMG_01895 8.8e-27 lanR K sequence-specific DNA binding
HNAFNGMG_01896 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HNAFNGMG_01897 6.5e-176 ytxK 2.1.1.72 L DNA methylase
HNAFNGMG_01898 5.2e-13 comGF U Putative Competence protein ComGF
HNAFNGMG_01899 2.9e-70 comGF U Competence protein ComGF
HNAFNGMG_01900 1.8e-15 NU Type II secretory pathway pseudopilin
HNAFNGMG_01901 3.5e-68 cglD NU Competence protein
HNAFNGMG_01902 6.5e-43 comGC U Required for transformation and DNA binding
HNAFNGMG_01903 1.7e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNAFNGMG_01904 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HNAFNGMG_01905 1e-68 S cog cog4699
HNAFNGMG_01906 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAFNGMG_01907 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAFNGMG_01908 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HNAFNGMG_01909 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HNAFNGMG_01910 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HNAFNGMG_01911 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
HNAFNGMG_01912 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HNAFNGMG_01913 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HNAFNGMG_01914 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
HNAFNGMG_01915 1.4e-57 asp S cog cog1302
HNAFNGMG_01916 9.6e-223 norN V Mate efflux family protein
HNAFNGMG_01917 1.9e-275 thrC 4.2.3.1 E Threonine synthase
HNAFNGMG_01920 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HNAFNGMG_01921 0.0 pepO 3.4.24.71 O Peptidase family M13
HNAFNGMG_01922 1.8e-181 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HNAFNGMG_01923 1.5e-83 treR K trehalose operon
HNAFNGMG_01924 5.1e-96 ywlG S Belongs to the UPF0340 family
HNAFNGMG_01927 4e-49
HNAFNGMG_01928 0.0 S Protein of unknown function DUF262
HNAFNGMG_01930 1.1e-57 L LlaJI restriction endonuclease
HNAFNGMG_01931 2e-93 V AAA domain (dynein-related subfamily)
HNAFNGMG_01933 1.6e-127 dcm_2 2.1.1.37 H overlaps another CDS with the same product name
HNAFNGMG_01934 1.4e-121 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HNAFNGMG_01935 2e-16 K Cro/C1-type HTH DNA-binding domain
HNAFNGMG_01936 4.2e-23
HNAFNGMG_01937 6.8e-106 K Peptidase S24-like protein
HNAFNGMG_01938 5.8e-115 E IrrE N-terminal-like domain
HNAFNGMG_01939 1.1e-10
HNAFNGMG_01941 4.3e-45 K Helix-turn-helix XRE-family like proteins
HNAFNGMG_01943 1e-42
HNAFNGMG_01944 5e-73
HNAFNGMG_01945 8.3e-275 ydcQ D Ftsk spoiiie family protein
HNAFNGMG_01946 6.4e-224 K Replication initiation factor
HNAFNGMG_01947 4.3e-33
HNAFNGMG_01948 1.9e-87
HNAFNGMG_01949 5.2e-160 S Conjugative transposon protein TcpC
HNAFNGMG_01950 3.2e-33
HNAFNGMG_01951 2.5e-68 S TcpE family
HNAFNGMG_01952 0.0 yddE S AAA-like domain
HNAFNGMG_01953 2.9e-260
HNAFNGMG_01954 2.6e-30
HNAFNGMG_01955 5.6e-171 isp2 S pathogenesis
HNAFNGMG_01956 3e-16
HNAFNGMG_01957 9.8e-186 L Phage integrase family
HNAFNGMG_01958 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HNAFNGMG_01960 1.9e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
HNAFNGMG_01961 4.4e-62 rplQ J ribosomal protein l17
HNAFNGMG_01962 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HNAFNGMG_01963 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HNAFNGMG_01964 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HNAFNGMG_01965 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HNAFNGMG_01966 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HNAFNGMG_01967 2.5e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HNAFNGMG_01968 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HNAFNGMG_01969 5.7e-58 rplO J binds to the 23S rRNA
HNAFNGMG_01970 1.9e-23 rpmD J ribosomal protein l30
HNAFNGMG_01971 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HNAFNGMG_01972 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HNAFNGMG_01973 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HNAFNGMG_01974 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HNAFNGMG_01975 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HNAFNGMG_01976 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HNAFNGMG_01977 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HNAFNGMG_01978 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HNAFNGMG_01979 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HNAFNGMG_01980 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HNAFNGMG_01981 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HNAFNGMG_01982 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HNAFNGMG_01983 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HNAFNGMG_01984 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HNAFNGMG_01985 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HNAFNGMG_01986 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HNAFNGMG_01987 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HNAFNGMG_01988 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HNAFNGMG_01989 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HNAFNGMG_01990 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HNAFNGMG_01991 0.0 XK27_09800 I Acyltransferase
HNAFNGMG_01992 2.8e-35 XK27_09805 S MORN repeat protein
HNAFNGMG_01993 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HNAFNGMG_01994 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HNAFNGMG_01995 5e-90 adk 2.7.4.3 F topology modulation protein
HNAFNGMG_01997 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HNAFNGMG_01998 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HNAFNGMG_01999 6.3e-44 yrzL S Belongs to the UPF0297 family
HNAFNGMG_02000 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HNAFNGMG_02001 3.2e-44 yrzB S Belongs to the UPF0473 family
HNAFNGMG_02002 5.8e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
HNAFNGMG_02003 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HNAFNGMG_02004 7.5e-14
HNAFNGMG_02005 1.2e-85 XK27_10930 K acetyltransferase
HNAFNGMG_02006 1e-113 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HNAFNGMG_02007 6.9e-119 yaaA S Belongs to the UPF0246 family
HNAFNGMG_02008 9.3e-167 XK27_01785 S cog cog1284
HNAFNGMG_02009 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HNAFNGMG_02011 8e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
HNAFNGMG_02012 8.6e-73 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_02013 5.8e-50 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_02014 8e-08 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HNAFNGMG_02015 1.2e-218 metE 2.1.1.14 E Methionine synthase
HNAFNGMG_02016 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HNAFNGMG_02017 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HNAFNGMG_02018 3.1e-130 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
HNAFNGMG_02019 1.1e-21 fruR K transcriptional
HNAFNGMG_02020 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HNAFNGMG_02021 5.3e-163 T Diguanylate cyclase
HNAFNGMG_02022 1.4e-19 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HNAFNGMG_02023 3.4e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HNAFNGMG_02024 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
HNAFNGMG_02025 0.0
HNAFNGMG_02026 5.1e-27 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HNAFNGMG_02027 1.2e-74
HNAFNGMG_02028 7.6e-110 K Peptidase S24-like protein
HNAFNGMG_02029 8.9e-107 E IrrE N-terminal-like domain
HNAFNGMG_02030 9.9e-93
HNAFNGMG_02031 3.8e-74
HNAFNGMG_02032 3.3e-07
HNAFNGMG_02035 3.8e-113 nudL L hydrolase
HNAFNGMG_02036 5e-51 K transcriptional regulator, PadR family
HNAFNGMG_02037 4e-59 XK27_06920 S Protein of unknown function (DUF1700)
HNAFNGMG_02038 1.6e-101 S Putative adhesin
HNAFNGMG_02039 3.9e-161 XK27_06930 V domain protein
HNAFNGMG_02040 1.3e-93 XK27_06935 K transcriptional regulator
HNAFNGMG_02041 2.2e-52 ypaA M Membrane
HNAFNGMG_02042 1.1e-10
HNAFNGMG_02043 7.1e-124
HNAFNGMG_02044 9.6e-08
HNAFNGMG_02045 2.6e-173 L virion core protein, lumpy skin disease virus
HNAFNGMG_02046 1.2e-74
HNAFNGMG_02047 7.5e-16
HNAFNGMG_02049 3.5e-09
HNAFNGMG_02050 3.1e-81 K Transcriptional
HNAFNGMG_02051 5.7e-182 sip L Phage integrase, N-terminal SAM-like domain
HNAFNGMG_02052 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HNAFNGMG_02053 1.8e-47 veg S Biofilm formation stimulator VEG
HNAFNGMG_02054 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HNAFNGMG_02055 2.2e-73 rplI J binds to the 23S rRNA
HNAFNGMG_02056 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HNAFNGMG_02057 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HNAFNGMG_02058 2.5e-96 yvbG U UPF0056 membrane protein
HNAFNGMG_02059 1.2e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HNAFNGMG_02060 4.6e-305 S Bacterial membrane protein, YfhO
HNAFNGMG_02061 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
HNAFNGMG_02062 1.9e-61 lytE M LysM domain protein
HNAFNGMG_02063 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAFNGMG_02064 1.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAFNGMG_02065 7.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HNAFNGMG_02066 5.9e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HNAFNGMG_02067 5.4e-129 S sequence-specific DNA binding
HNAFNGMG_02068 4.6e-233 ymfH S Peptidase M16
HNAFNGMG_02069 1.3e-227 ymfF S Peptidase M16
HNAFNGMG_02070 6.4e-58 yaaA S S4 domain protein YaaA
HNAFNGMG_02071 1.2e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HNAFNGMG_02072 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HNAFNGMG_02073 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HNAFNGMG_02074 9.3e-153 yvjA S membrane
HNAFNGMG_02075 1.1e-305 ybiT S abc transporter atp-binding protein
HNAFNGMG_02076 0.0 XK27_10405 S Bacterial membrane protein YfhO
HNAFNGMG_02080 2.2e-117 yoaK S Protein of unknown function (DUF1275)
HNAFNGMG_02081 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HNAFNGMG_02082 5.8e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HNAFNGMG_02083 3.2e-133 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)