ORF_ID e_value Gene_name EC_number CAZy COGs Description
EDPEAEPI_00001 1e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EDPEAEPI_00002 5.5e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EDPEAEPI_00003 1.1e-29 yyzM S Protein conserved in bacteria
EDPEAEPI_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EDPEAEPI_00005 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EDPEAEPI_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EDPEAEPI_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EDPEAEPI_00008 3e-60 divIC D Septum formation initiator
EDPEAEPI_00010 8.4e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EDPEAEPI_00011 4.1e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EDPEAEPI_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EDPEAEPI_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EDPEAEPI_00026 2.6e-10
EDPEAEPI_00032 6.6e-92 mreC M Involved in formation and maintenance of cell shape
EDPEAEPI_00033 6.1e-83 mreD M rod shape-determining protein MreD
EDPEAEPI_00034 1.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
EDPEAEPI_00035 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDPEAEPI_00036 9.4e-217 araT 2.6.1.1 E Aminotransferase
EDPEAEPI_00037 1e-139 recO L Involved in DNA repair and RecF pathway recombination
EDPEAEPI_00038 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EDPEAEPI_00039 2.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDPEAEPI_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EDPEAEPI_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDPEAEPI_00042 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EDPEAEPI_00043 5.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EDPEAEPI_00044 2.4e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EDPEAEPI_00045 2.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EDPEAEPI_00046 1.3e-156 S CHAP domain
EDPEAEPI_00047 7.2e-239 purD 6.3.4.13 F Belongs to the GARS family
EDPEAEPI_00048 9.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EDPEAEPI_00049 3.6e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EDPEAEPI_00050 4.4e-172 1.1.1.169 H Ketopantoate reductase
EDPEAEPI_00051 3.3e-33
EDPEAEPI_00052 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EDPEAEPI_00053 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDPEAEPI_00054 3.1e-69 argR K Regulates arginine biosynthesis genes
EDPEAEPI_00055 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EDPEAEPI_00056 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EDPEAEPI_00057 1.5e-77 S Protein of unknown function (DUF3021)
EDPEAEPI_00058 1.1e-69 K LytTr DNA-binding domain
EDPEAEPI_00060 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EDPEAEPI_00062 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EDPEAEPI_00063 5.1e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EDPEAEPI_00064 2.2e-227 cinA 3.5.1.42 S Belongs to the CinA family
EDPEAEPI_00065 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EDPEAEPI_00066 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EDPEAEPI_00072 2.6e-10
EDPEAEPI_00075 1.9e-07
EDPEAEPI_00080 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDPEAEPI_00081 6.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EDPEAEPI_00082 5.5e-36 XK27_02060 S Transglycosylase associated protein
EDPEAEPI_00083 2.6e-71 badR K Transcriptional regulator, marr family
EDPEAEPI_00084 3.2e-95 S reductase
EDPEAEPI_00086 6.6e-287 ahpF O alkyl hydroperoxide reductase
EDPEAEPI_00087 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
EDPEAEPI_00088 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
EDPEAEPI_00089 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EDPEAEPI_00090 1.2e-82 S Putative small multi-drug export protein
EDPEAEPI_00091 2e-74 ctsR K Belongs to the CtsR family
EDPEAEPI_00092 0.0 clpC O Belongs to the ClpA ClpB family
EDPEAEPI_00093 2.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDPEAEPI_00094 2.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDPEAEPI_00095 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EDPEAEPI_00096 2.7e-140 S SseB protein N-terminal domain
EDPEAEPI_00097 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
EDPEAEPI_00098 4.4e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDPEAEPI_00099 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EDPEAEPI_00101 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDPEAEPI_00102 6e-91 yacP S RNA-binding protein containing a PIN domain
EDPEAEPI_00103 1e-151 degV S DegV family
EDPEAEPI_00105 5.1e-22 K Transcriptional
EDPEAEPI_00106 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EDPEAEPI_00107 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EDPEAEPI_00108 2.5e-104 yiiE S protein homotetramerization
EDPEAEPI_00109 7.6e-18
EDPEAEPI_00110 1.5e-29 K Helix-turn-helix domain
EDPEAEPI_00112 4.6e-149 srtB 3.4.22.70 S Sortase family
EDPEAEPI_00113 5.7e-233 capA M Bacterial capsule synthesis protein
EDPEAEPI_00114 6.1e-39 gcvR T UPF0237 protein
EDPEAEPI_00115 6.6e-243 XK27_08635 S UPF0210 protein
EDPEAEPI_00116 2.8e-131 ais G Phosphoglycerate mutase
EDPEAEPI_00117 1.8e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EDPEAEPI_00118 7.9e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
EDPEAEPI_00119 9.2e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EDPEAEPI_00120 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EDPEAEPI_00121 6e-303 dnaK O Heat shock 70 kDa protein
EDPEAEPI_00122 7.5e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
EDPEAEPI_00123 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EDPEAEPI_00124 1.1e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EDPEAEPI_00125 1.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EDPEAEPI_00126 7.4e-80 hmpT S cog cog4720
EDPEAEPI_00139 3.9e-87 sigH K DNA-templated transcription, initiation
EDPEAEPI_00140 3.1e-139 ykuT M mechanosensitive ion channel
EDPEAEPI_00141 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EDPEAEPI_00142 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EDPEAEPI_00143 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EDPEAEPI_00144 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
EDPEAEPI_00145 3.5e-74 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EDPEAEPI_00146 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
EDPEAEPI_00147 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EDPEAEPI_00148 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDPEAEPI_00149 3.1e-83 nrdI F Belongs to the NrdI family
EDPEAEPI_00150 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EDPEAEPI_00151 5.7e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EDPEAEPI_00152 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDPEAEPI_00153 1.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EDPEAEPI_00154 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EDPEAEPI_00155 2.2e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EDPEAEPI_00156 4e-191 yhjX P Major Facilitator
EDPEAEPI_00157 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EDPEAEPI_00158 2.8e-84 V VanZ like family
EDPEAEPI_00159 2.7e-184 D nuclear chromosome segregation
EDPEAEPI_00160 2.2e-123 glnQ E abc transporter atp-binding protein
EDPEAEPI_00161 4.2e-273 glnP P ABC transporter
EDPEAEPI_00162 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EDPEAEPI_00163 8.3e-18 S Protein of unknown function (DUF3021)
EDPEAEPI_00164 5.7e-127 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EDPEAEPI_00165 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
EDPEAEPI_00166 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EDPEAEPI_00167 1.2e-233 sufD O assembly protein SufD
EDPEAEPI_00168 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EDPEAEPI_00169 2.7e-73 nifU C SUF system FeS assembly protein, NifU family
EDPEAEPI_00170 1.9e-272 sufB O assembly protein SufB
EDPEAEPI_00171 2.7e-26
EDPEAEPI_00172 7.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EDPEAEPI_00173 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDPEAEPI_00174 2e-71 adcR K transcriptional
EDPEAEPI_00175 2.4e-135 adcC P ABC transporter, ATP-binding protein
EDPEAEPI_00176 2.7e-130 adcB P ABC transporter (Permease
EDPEAEPI_00177 2.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EDPEAEPI_00178 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_00179 2.9e-156 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EDPEAEPI_00180 3.3e-234 pgi 5.3.1.9 G Belongs to the GPI family
EDPEAEPI_00181 8.6e-25
EDPEAEPI_00182 2.4e-304 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EDPEAEPI_00183 6e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EDPEAEPI_00184 1e-36 srlM 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDPEAEPI_00185 5.2e-57 gutM K Glucitol operon activator
EDPEAEPI_00186 2.4e-82 srlA G PTS system glucitol sorbitol-specific
EDPEAEPI_00187 2.2e-158 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
EDPEAEPI_00188 1.1e-33 srlB 2.7.1.198 G sorbitol-specific, IIA component
EDPEAEPI_00189 4.8e-21 tal 2.2.1.2 H Transaldolase
EDPEAEPI_00190 3.8e-64 V ABC transporter
EDPEAEPI_00191 6.1e-126 yeeN K transcriptional regulatory protein
EDPEAEPI_00192 4.5e-47 yajC U protein transport
EDPEAEPI_00193 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EDPEAEPI_00194 2.7e-143 cdsA 2.7.7.41 S Belongs to the CDS family
EDPEAEPI_00195 2.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EDPEAEPI_00196 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EDPEAEPI_00197 0.0 WQ51_06230 S ABC transporter
EDPEAEPI_00198 1.4e-142 cmpC S abc transporter atp-binding protein
EDPEAEPI_00199 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EDPEAEPI_00200 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EDPEAEPI_00202 5.5e-44
EDPEAEPI_00203 7.6e-55 S TM2 domain
EDPEAEPI_00204 7.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDPEAEPI_00205 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDPEAEPI_00206 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EDPEAEPI_00207 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
EDPEAEPI_00208 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EDPEAEPI_00209 1.8e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EDPEAEPI_00210 2.7e-146 cof S Sucrose-6F-phosphate phosphohydrolase
EDPEAEPI_00211 3.6e-132 glcR K transcriptional regulator (DeoR family)
EDPEAEPI_00212 6e-93 leuS 6.1.1.4 J Leucyl-tRNA synthetase, Domain 2
EDPEAEPI_00213 1.1e-286 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDPEAEPI_00214 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
EDPEAEPI_00215 2.5e-231 S COG1073 Hydrolases of the alpha beta superfamily
EDPEAEPI_00216 6e-152 cylA V abc transporter atp-binding protein
EDPEAEPI_00217 3.4e-128 cylB V ABC-2 type transporter
EDPEAEPI_00218 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
EDPEAEPI_00219 8.9e-32 S Protein of unknown function (DUF3021)
EDPEAEPI_00220 9.6e-124 mta K Transcriptional
EDPEAEPI_00221 6.2e-120 yhcA V abc transporter atp-binding protein
EDPEAEPI_00222 2.3e-216 macB_2 V FtsX-like permease family
EDPEAEPI_00223 4.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EDPEAEPI_00224 3.4e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EDPEAEPI_00225 1.7e-73 yhaI S Protein of unknown function (DUF805)
EDPEAEPI_00226 2.6e-255 pepC 3.4.22.40 E aminopeptidase
EDPEAEPI_00227 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDPEAEPI_00228 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EDPEAEPI_00229 5.8e-94 ypsA S Belongs to the UPF0398 family
EDPEAEPI_00230 1.6e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EDPEAEPI_00231 2.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EDPEAEPI_00232 2.6e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EDPEAEPI_00233 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EDPEAEPI_00234 9.6e-23
EDPEAEPI_00235 1.2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EDPEAEPI_00236 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
EDPEAEPI_00237 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EDPEAEPI_00238 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EDPEAEPI_00239 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDPEAEPI_00240 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EDPEAEPI_00241 5.6e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDPEAEPI_00242 2.8e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EDPEAEPI_00243 1e-98 ybhL S Belongs to the BI1 family
EDPEAEPI_00244 1.9e-09 ycdA S Domain of unknown function (DUF4352)
EDPEAEPI_00245 1.5e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EDPEAEPI_00246 4.5e-89 K transcriptional regulator
EDPEAEPI_00247 1.6e-36 yneF S UPF0154 protein
EDPEAEPI_00248 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EDPEAEPI_00249 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EDPEAEPI_00250 5.6e-97 XK27_09740 S Phosphoesterase
EDPEAEPI_00251 2.1e-85 ykuL S CBS domain
EDPEAEPI_00252 8e-132 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EDPEAEPI_00253 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EDPEAEPI_00254 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EDPEAEPI_00255 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDPEAEPI_00256 1.5e-12 yidD M Could be involved in insertion of integral membrane proteins into the membrane
EDPEAEPI_00257 4.2e-259 trkH P Cation transport protein
EDPEAEPI_00258 3.8e-246 trkA P Potassium transporter peripheral membrane component
EDPEAEPI_00259 2.4e-92 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EDPEAEPI_00260 2.1e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EDPEAEPI_00261 4.7e-101 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EDPEAEPI_00262 5.1e-154 K sequence-specific DNA binding
EDPEAEPI_00263 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDPEAEPI_00264 1.3e-54 yhaI L Membrane
EDPEAEPI_00265 1.2e-247 S Domain of unknown function (DUF4173)
EDPEAEPI_00266 3.1e-137 ET ABC transporter substrate-binding protein
EDPEAEPI_00267 1.2e-163 metQ M Belongs to the NlpA lipoprotein family
EDPEAEPI_00268 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EDPEAEPI_00269 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EDPEAEPI_00270 8e-99 metI P ABC transporter (Permease
EDPEAEPI_00271 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EDPEAEPI_00272 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EDPEAEPI_00273 6.7e-93 S UPF0397 protein
EDPEAEPI_00274 1.9e-308 ykoD P abc transporter atp-binding protein
EDPEAEPI_00275 3.8e-148 cbiQ P cobalt transport
EDPEAEPI_00276 3e-119 ktrA P COG0569 K transport systems, NAD-binding component
EDPEAEPI_00277 8.3e-233 P COG0168 Trk-type K transport systems, membrane components
EDPEAEPI_00278 2.1e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EDPEAEPI_00279 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
EDPEAEPI_00280 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDPEAEPI_00281 4.6e-280 T PhoQ Sensor
EDPEAEPI_00282 3.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EDPEAEPI_00283 1e-215 dnaB L Replication initiation and membrane attachment
EDPEAEPI_00284 4.4e-166 dnaI L Primosomal protein DnaI
EDPEAEPI_00285 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EDPEAEPI_00286 2.2e-111
EDPEAEPI_00287 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EDPEAEPI_00288 2.5e-62 manO S protein conserved in bacteria
EDPEAEPI_00289 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
EDPEAEPI_00290 2e-117 manM G pts system
EDPEAEPI_00291 4.9e-174 manL 2.7.1.191 G pts system
EDPEAEPI_00292 2.2e-66 manO S Protein conserved in bacteria
EDPEAEPI_00293 5.3e-159 manN G PTS system mannose fructose sorbose family IID component
EDPEAEPI_00294 3.4e-133 manY G pts system
EDPEAEPI_00295 6.2e-169 manL 2.7.1.191 G pts system
EDPEAEPI_00296 3.5e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EDPEAEPI_00297 1.3e-23 L Transposase
EDPEAEPI_00298 1.1e-48 blpT
EDPEAEPI_00299 6.5e-10
EDPEAEPI_00300 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDPEAEPI_00301 1.3e-100 mesE M Transport protein ComB
EDPEAEPI_00302 7.2e-96 blpH 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_00303 5.4e-61 agrA KT LytTr DNA-binding domain
EDPEAEPI_00304 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EDPEAEPI_00305 1.2e-247 pbuO S permease
EDPEAEPI_00306 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EDPEAEPI_00307 8.7e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
EDPEAEPI_00308 4.4e-188 brpA K Transcriptional
EDPEAEPI_00309 6.7e-81 rimP S Required for maturation of 30S ribosomal subunits
EDPEAEPI_00310 1.6e-195 nusA K Participates in both transcription termination and antitermination
EDPEAEPI_00311 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EDPEAEPI_00312 8e-42 ylxQ J ribosomal protein
EDPEAEPI_00313 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EDPEAEPI_00314 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EDPEAEPI_00315 1.7e-99 yvdD 3.2.2.10 S Belongs to the LOG family
EDPEAEPI_00316 3.4e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EDPEAEPI_00317 1.9e-281 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EDPEAEPI_00318 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EDPEAEPI_00319 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
EDPEAEPI_00320 2.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EDPEAEPI_00321 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EDPEAEPI_00322 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
EDPEAEPI_00323 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EDPEAEPI_00324 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EDPEAEPI_00325 2.1e-68 ylbF S Belongs to the UPF0342 family
EDPEAEPI_00326 2.7e-45 ylbG S UPF0298 protein
EDPEAEPI_00327 5.3e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EDPEAEPI_00328 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
EDPEAEPI_00329 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
EDPEAEPI_00330 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EDPEAEPI_00331 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EDPEAEPI_00332 1.6e-112 acuB S CBS domain
EDPEAEPI_00333 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EDPEAEPI_00334 3.8e-108 yvyE 3.4.13.9 S YigZ family
EDPEAEPI_00335 1.8e-248 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EDPEAEPI_00336 1.3e-82 comFC K competence protein
EDPEAEPI_00337 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EDPEAEPI_00345 3.3e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
EDPEAEPI_00346 1.5e-104 S Domain of unknown function (DUF1803)
EDPEAEPI_00347 7.8e-102 ygaC J Belongs to the UPF0374 family
EDPEAEPI_00348 5.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
EDPEAEPI_00349 2.6e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDPEAEPI_00350 2e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
EDPEAEPI_00351 4.5e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
EDPEAEPI_00352 8.1e-114 S HAD hydrolase, family IA, variant 3
EDPEAEPI_00353 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EDPEAEPI_00354 5.2e-72 marR K Transcriptional regulator, MarR family
EDPEAEPI_00355 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EDPEAEPI_00356 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDPEAEPI_00357 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EDPEAEPI_00358 1.2e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EDPEAEPI_00359 1.8e-125 IQ reductase
EDPEAEPI_00360 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EDPEAEPI_00361 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EDPEAEPI_00362 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EDPEAEPI_00363 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EDPEAEPI_00364 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EDPEAEPI_00365 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EDPEAEPI_00366 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EDPEAEPI_00367 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
EDPEAEPI_00368 2.3e-112 fruR K transcriptional
EDPEAEPI_00369 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EDPEAEPI_00370 5.9e-242 fruA 2.7.1.202 G phosphotransferase system
EDPEAEPI_00371 4.3e-258 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDPEAEPI_00372 1.2e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDPEAEPI_00374 1.2e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EDPEAEPI_00375 2.2e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDPEAEPI_00376 3.9e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EDPEAEPI_00377 1.7e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EDPEAEPI_00378 2.3e-93 2.3.1.128 K acetyltransferase
EDPEAEPI_00379 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EDPEAEPI_00380 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EDPEAEPI_00381 4.7e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDPEAEPI_00382 2.1e-61 WQ51_03320 S cog cog4835
EDPEAEPI_00383 5.6e-147 XK27_08360 S EDD domain protein, DegV family
EDPEAEPI_00384 3.9e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EDPEAEPI_00385 7.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EDPEAEPI_00386 0.0 yfmR S abc transporter atp-binding protein
EDPEAEPI_00387 1.3e-26 U response to pH
EDPEAEPI_00388 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EDPEAEPI_00389 3.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EDPEAEPI_00390 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EDPEAEPI_00391 4.6e-270 S Psort location CytoplasmicMembrane, score
EDPEAEPI_00392 2.3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EDPEAEPI_00393 3.3e-74 K DNA-binding transcription factor activity
EDPEAEPI_00394 0.0 lmrA1 V abc transporter atp-binding protein
EDPEAEPI_00395 0.0 lmrA2 V abc transporter atp-binding protein
EDPEAEPI_00396 1.1e-112 K Acetyltransferase (GNAT) family
EDPEAEPI_00397 1.6e-111 2.7.6.5 S Region found in RelA / SpoT proteins
EDPEAEPI_00398 1.7e-117 T response regulator
EDPEAEPI_00399 1.8e-215 sptS 2.7.13.3 T Histidine kinase
EDPEAEPI_00400 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EDPEAEPI_00401 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EDPEAEPI_00402 4.2e-158 cvfB S Protein conserved in bacteria
EDPEAEPI_00403 3.7e-34 yozE S Belongs to the UPF0346 family
EDPEAEPI_00404 5.2e-128 sip M LysM domain protein
EDPEAEPI_00405 4.9e-188 phoH T phosphate starvation-inducible protein PhoH
EDPEAEPI_00409 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EDPEAEPI_00410 2.2e-159 S reductase
EDPEAEPI_00411 4.7e-168 K transcriptional regulator (lysR family)
EDPEAEPI_00412 5.5e-106 S CAAX amino terminal protease family protein
EDPEAEPI_00413 5.4e-278 S Glucan-binding protein C
EDPEAEPI_00414 3.2e-170 coiA 3.6.4.12 S Competence protein
EDPEAEPI_00415 0.0 pepF E oligoendopeptidase F
EDPEAEPI_00416 9.4e-212 oxlT P COG0477 Permeases of the major facilitator superfamily
EDPEAEPI_00417 2.1e-126 yrrM 2.1.1.104 S O-Methyltransferase
EDPEAEPI_00418 5.1e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EDPEAEPI_00419 3.9e-84 yxjI S LURP-one-related
EDPEAEPI_00420 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EDPEAEPI_00421 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDPEAEPI_00422 4.4e-135 agrA KT response regulator
EDPEAEPI_00423 4.4e-266 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
EDPEAEPI_00424 7.3e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EDPEAEPI_00425 1.8e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EDPEAEPI_00426 2.2e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EDPEAEPI_00427 3.9e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EDPEAEPI_00428 3.1e-125 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EDPEAEPI_00429 9.7e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EDPEAEPI_00430 2.7e-128 yxkH G deacetylase
EDPEAEPI_00431 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EDPEAEPI_00432 4.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EDPEAEPI_00433 5.3e-148 rarD S Transporter
EDPEAEPI_00434 5.8e-16 T peptidase
EDPEAEPI_00435 3e-14 coiA 3.6.4.12 S Competence protein
EDPEAEPI_00438 9.9e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EDPEAEPI_00439 2.5e-98 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EDPEAEPI_00440 7.4e-19
EDPEAEPI_00442 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EDPEAEPI_00443 6.1e-300
EDPEAEPI_00444 7.2e-150 dam2 2.1.1.72 L DNA methyltransferase
EDPEAEPI_00445 8.6e-47
EDPEAEPI_00446 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDPEAEPI_00447 3.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
EDPEAEPI_00448 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EDPEAEPI_00449 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDPEAEPI_00450 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EDPEAEPI_00451 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EDPEAEPI_00452 6.7e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EDPEAEPI_00453 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EDPEAEPI_00454 3.7e-227 L Transposase
EDPEAEPI_00455 7.1e-218 ftsW D Belongs to the SEDS family
EDPEAEPI_00456 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EDPEAEPI_00457 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EDPEAEPI_00458 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EDPEAEPI_00460 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EDPEAEPI_00461 2.1e-160 holB 2.7.7.7 L dna polymerase iii
EDPEAEPI_00462 1.3e-129 yaaT S stage 0 sporulation protein
EDPEAEPI_00463 1.2e-54 yabA L Involved in initiation control of chromosome replication
EDPEAEPI_00464 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EDPEAEPI_00465 2.1e-227 amt P Ammonium Transporter
EDPEAEPI_00466 1.9e-53 glnB K Belongs to the P(II) protein family
EDPEAEPI_00467 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
EDPEAEPI_00468 1.9e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EDPEAEPI_00469 4.9e-80 S Bacterial inner membrane protein
EDPEAEPI_00470 7e-99 3.4.17.14, 3.5.1.28 NU amidase activity
EDPEAEPI_00471 3.5e-294 nptA P COG1283 Na phosphate symporter
EDPEAEPI_00472 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EDPEAEPI_00473 4.6e-222 S membrane
EDPEAEPI_00474 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EDPEAEPI_00475 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EDPEAEPI_00476 1.7e-38 ynzC S UPF0291 protein
EDPEAEPI_00477 1.1e-253 cycA E permease
EDPEAEPI_00478 3.7e-10 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDPEAEPI_00479 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_00480 3.5e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDPEAEPI_00484 2.2e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
EDPEAEPI_00485 1.8e-56 V ABC-2 type transporter
EDPEAEPI_00486 4.5e-95
EDPEAEPI_00488 1.2e-166 fhuR K transcriptional regulator (lysR family)
EDPEAEPI_00489 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EDPEAEPI_00490 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDPEAEPI_00491 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EDPEAEPI_00492 1.4e-221 pyrP F uracil Permease
EDPEAEPI_00493 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EDPEAEPI_00494 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EDPEAEPI_00495 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EDPEAEPI_00496 3.1e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
EDPEAEPI_00498 4.8e-192 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
EDPEAEPI_00500 6.9e-133 agrA KT phosphorelay signal transduction system
EDPEAEPI_00501 1.8e-229 2.7.13.3 T GHKL domain
EDPEAEPI_00502 9.7e-119 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDPEAEPI_00503 2e-121 macB V ABC transporter, ATP-binding protein
EDPEAEPI_00504 2.1e-211 V permease protein
EDPEAEPI_00505 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EDPEAEPI_00506 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EDPEAEPI_00507 0.0 mdlB V abc transporter atp-binding protein
EDPEAEPI_00508 0.0 lmrA V abc transporter atp-binding protein
EDPEAEPI_00509 1.9e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EDPEAEPI_00510 5.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EDPEAEPI_00511 2.6e-196 yceA S Belongs to the UPF0176 family
EDPEAEPI_00512 1.6e-28 XK27_00085 K Transcriptional
EDPEAEPI_00513 4.7e-21
EDPEAEPI_00514 8.5e-134 deoD_1 2.4.2.3 F Phosphorylase superfamily
EDPEAEPI_00515 8.7e-114 S VIT family
EDPEAEPI_00516 5.5e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDPEAEPI_00517 3.8e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDPEAEPI_00518 3e-10 puuD T peptidase C26
EDPEAEPI_00519 6.2e-194 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EDPEAEPI_00521 5e-137 E Alpha beta hydrolase
EDPEAEPI_00522 2.8e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDPEAEPI_00523 1e-107 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EDPEAEPI_00524 2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EDPEAEPI_00525 1.2e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EDPEAEPI_00526 6.8e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EDPEAEPI_00527 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
EDPEAEPI_00528 1.3e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EDPEAEPI_00529 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EDPEAEPI_00530 2.9e-25
EDPEAEPI_00531 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EDPEAEPI_00532 0.0 U protein secretion
EDPEAEPI_00533 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EDPEAEPI_00534 2.6e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EDPEAEPI_00536 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EDPEAEPI_00537 1.4e-162 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EDPEAEPI_00538 7.2e-200 S Protein of unknown function (DUF3114)
EDPEAEPI_00539 4.1e-29 pspC KT PspC domain protein
EDPEAEPI_00540 5.2e-119 yqfA K protein, Hemolysin III
EDPEAEPI_00541 3e-78 K hmm pf08876
EDPEAEPI_00542 1e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EDPEAEPI_00543 4.9e-210 mvaS 2.3.3.10 I synthase
EDPEAEPI_00544 1.7e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EDPEAEPI_00545 2.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EDPEAEPI_00546 9.7e-22
EDPEAEPI_00547 4.4e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EDPEAEPI_00548 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EDPEAEPI_00549 1.7e-249 mmuP E amino acid
EDPEAEPI_00550 1e-165 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EDPEAEPI_00551 2.2e-30 S Domain of unknown function (DUF1912)
EDPEAEPI_00552 2e-14 L Helix-hairpin-helix DNA-binding motif class 1
EDPEAEPI_00553 5.6e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EDPEAEPI_00554 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDPEAEPI_00556 8.1e-44
EDPEAEPI_00557 5.3e-52 K acetyltransferase
EDPEAEPI_00559 3.5e-76 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDPEAEPI_00560 2.4e-13 S AAA ATPase domain
EDPEAEPI_00563 1.1e-123 aadK G adenylyltransferase
EDPEAEPI_00564 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDPEAEPI_00565 5.3e-200 ilvE 2.6.1.42 E Aminotransferase
EDPEAEPI_00566 4.8e-16 S Protein of unknown function (DUF2969)
EDPEAEPI_00569 7.1e-204 rpsA 1.17.7.4 J ribosomal protein S1
EDPEAEPI_00570 3.7e-227 L Transposase
EDPEAEPI_00573 5.5e-107 S Domain of Unknown Function with PDB structure (DUF3862)
EDPEAEPI_00574 1.2e-115 M Pfam SNARE associated Golgi protein
EDPEAEPI_00575 7.3e-228 murN 2.3.2.16 V FemAB family
EDPEAEPI_00576 7.5e-172 S oxidoreductase
EDPEAEPI_00577 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
EDPEAEPI_00578 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EDPEAEPI_00579 0.0 clpE O Belongs to the ClpA ClpB family
EDPEAEPI_00580 6.9e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EDPEAEPI_00581 1e-34 ykuJ S protein conserved in bacteria
EDPEAEPI_00582 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EDPEAEPI_00583 2.1e-129 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_00584 1.6e-77 feoA P FeoA domain protein
EDPEAEPI_00585 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EDPEAEPI_00586 6.6e-08
EDPEAEPI_00587 2.3e-147 I Alpha/beta hydrolase family
EDPEAEPI_00588 2.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EDPEAEPI_00589 4.1e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EDPEAEPI_00590 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EDPEAEPI_00591 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EDPEAEPI_00592 7.4e-83 licT K antiterminator
EDPEAEPI_00593 5.7e-52 licT K antiterminator
EDPEAEPI_00594 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EDPEAEPI_00595 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EDPEAEPI_00596 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EDPEAEPI_00597 2.4e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EDPEAEPI_00598 1.2e-98 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EDPEAEPI_00599 3.2e-220 mdtG EGP Major facilitator Superfamily
EDPEAEPI_00600 2e-33 secG U Preprotein translocase subunit SecG
EDPEAEPI_00601 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EDPEAEPI_00602 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EDPEAEPI_00603 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDPEAEPI_00604 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EDPEAEPI_00605 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EDPEAEPI_00606 2.4e-181 ccpA K Catabolite control protein A
EDPEAEPI_00607 2.5e-200 yyaQ S YjbR
EDPEAEPI_00608 2.1e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EDPEAEPI_00609 9e-75 yueI S Protein of unknown function (DUF1694)
EDPEAEPI_00610 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EDPEAEPI_00611 4.6e-25 WQ51_00785
EDPEAEPI_00612 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EDPEAEPI_00613 3.2e-217 ywbD 2.1.1.191 J Methyltransferase
EDPEAEPI_00614 5.8e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EDPEAEPI_00615 1.2e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDPEAEPI_00616 5.4e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EDPEAEPI_00617 4.2e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EDPEAEPI_00618 1.7e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EDPEAEPI_00619 4.2e-53 yheA S Belongs to the UPF0342 family
EDPEAEPI_00620 3.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EDPEAEPI_00621 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EDPEAEPI_00622 1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EDPEAEPI_00623 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
EDPEAEPI_00624 3.1e-246 msrR K Transcriptional regulator
EDPEAEPI_00625 4.2e-103 ydiA P C4-dicarboxylate transporter malic acid transport
EDPEAEPI_00626 3.3e-176 I acyl-CoA dehydrogenase
EDPEAEPI_00627 5.9e-97 mip S hydroperoxide reductase activity
EDPEAEPI_00628 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDPEAEPI_00629 3.6e-91 K Acetyltransferase (GNAT) domain
EDPEAEPI_00630 1.2e-92
EDPEAEPI_00632 8.8e-113 K Bacterial regulatory proteins, tetR family
EDPEAEPI_00633 2.4e-117 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
EDPEAEPI_00634 3.9e-128 bcrA V abc transporter atp-binding protein
EDPEAEPI_00635 4.1e-282 V ABC transporter transmembrane region
EDPEAEPI_00636 4.3e-22
EDPEAEPI_00637 2e-217 EGP Transmembrane secretion effector
EDPEAEPI_00638 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
EDPEAEPI_00639 1.1e-49
EDPEAEPI_00640 8.7e-60
EDPEAEPI_00641 5.9e-55
EDPEAEPI_00642 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDPEAEPI_00643 1.8e-128 S CAAX amino terminal protease family protein
EDPEAEPI_00644 3.9e-142 S CAAX protease self-immunity
EDPEAEPI_00645 3.5e-147 K Helix-turn-helix XRE-family like proteins
EDPEAEPI_00646 2e-135 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EDPEAEPI_00647 3e-136 S Domain of unknown function (DUF4336)
EDPEAEPI_00648 9.1e-204 yeaN P transporter
EDPEAEPI_00649 5.4e-150 yitS S EDD domain protein, DegV family
EDPEAEPI_00650 1.2e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
EDPEAEPI_00651 6.8e-129 S CAAX amino terminal protease family
EDPEAEPI_00652 8.6e-108 cutC P Participates in the control of copper homeostasis
EDPEAEPI_00654 2.4e-21 S Domain of unknown function (DUF4767)
EDPEAEPI_00655 3.6e-154 S Domain of unknown function (DUF4300)
EDPEAEPI_00656 3.8e-115 V CAAX protease self-immunity
EDPEAEPI_00657 7.4e-157 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDPEAEPI_00658 2.2e-134 fecE 3.6.3.34 HP ABC transporter
EDPEAEPI_00659 1.1e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EDPEAEPI_00660 3.4e-126 ybbA S Putative esterase
EDPEAEPI_00661 2.4e-278 4.2.1.53 S MCRA family
EDPEAEPI_00664 2.1e-172 S Domain of unknown function (DUF389)
EDPEAEPI_00665 7.2e-31 S Membrane
EDPEAEPI_00666 2.9e-09 S CsbD-like
EDPEAEPI_00667 2.3e-171 pdhD 1.8.1.4 C Dehydrogenase
EDPEAEPI_00668 9.6e-168 acoA C Acetoin dehydrogenase E1 component subunit alpha
EDPEAEPI_00669 5e-174 acoB C dehydrogenase E1 component
EDPEAEPI_00670 6.5e-144 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EDPEAEPI_00671 7.9e-46
EDPEAEPI_00672 5.7e-127 V CAAX protease self-immunity
EDPEAEPI_00673 4.9e-09
EDPEAEPI_00674 2.6e-20 M Bacterial lipoprotein
EDPEAEPI_00675 2.9e-61 S Protein of unknown function (DUF1722)
EDPEAEPI_00676 3.7e-63 yqeB S Pyrimidine dimer DNA glycosylase
EDPEAEPI_00678 1e-49
EDPEAEPI_00679 8.1e-87 S CAAX protease self-immunity
EDPEAEPI_00680 1.4e-113 estA E GDSL-like Lipase/Acylhydrolase
EDPEAEPI_00681 2.6e-101
EDPEAEPI_00682 1e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
EDPEAEPI_00683 8.4e-148 ycgQ S TIGR03943 family
EDPEAEPI_00684 2.7e-155 XK27_03015 S permease
EDPEAEPI_00686 0.0 yhgF K Transcriptional accessory protein
EDPEAEPI_00687 6e-84 ydcK S Belongs to the SprT family
EDPEAEPI_00688 2.2e-41 pspC KT PspC domain
EDPEAEPI_00689 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EDPEAEPI_00690 6.4e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EDPEAEPI_00691 8.3e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EDPEAEPI_00692 3.2e-61 ytxH S General stress protein
EDPEAEPI_00694 2.6e-177 yegQ O Peptidase U32
EDPEAEPI_00695 7.5e-252 yegQ O Peptidase U32
EDPEAEPI_00696 1e-85 bioY S biotin synthase
EDPEAEPI_00698 1.1e-33 XK27_12190 S protein conserved in bacteria
EDPEAEPI_00699 2.4e-232 mntH P H( )-stimulated, divalent metal cation uptake system
EDPEAEPI_00700 3e-13
EDPEAEPI_00701 2.8e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
EDPEAEPI_00702 0.0 L helicase
EDPEAEPI_00703 5.6e-15
EDPEAEPI_00704 4.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EDPEAEPI_00705 7.4e-138 M LysM domain
EDPEAEPI_00706 8.4e-23
EDPEAEPI_00707 5.2e-175 S hydrolase
EDPEAEPI_00709 5.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EDPEAEPI_00710 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EDPEAEPI_00711 1.6e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EDPEAEPI_00712 1.2e-26 P Hemerythrin HHE cation binding domain protein
EDPEAEPI_00713 2.9e-159 5.2.1.8 G hydrolase
EDPEAEPI_00714 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EDPEAEPI_00715 9.9e-211 MA20_36090 S Protein of unknown function (DUF2974)
EDPEAEPI_00716 3e-131 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDPEAEPI_00718 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EDPEAEPI_00720 1e-36 immA E Zn peptidase
EDPEAEPI_00721 8.6e-73 T Pfam Adenylate and Guanylate cyclase catalytic domain
EDPEAEPI_00722 1.6e-110 3.1.21.3 V Type I restriction modification DNA specificity domain
EDPEAEPI_00723 3.1e-303 hsdM 2.1.1.72 V type I restriction-modification system
EDPEAEPI_00724 9.5e-129 S double-stranded DNA endodeoxyribonuclease activity
EDPEAEPI_00725 0.0 2.4.1.21 GT5 M Right handed beta helix region
EDPEAEPI_00726 7.7e-92 lemA S LemA family
EDPEAEPI_00727 4e-135 htpX O Belongs to the peptidase M48B family
EDPEAEPI_00728 1.9e-118 sirR K iron dependent repressor
EDPEAEPI_00729 3e-170 sitA P Belongs to the bacterial solute-binding protein 9 family
EDPEAEPI_00730 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
EDPEAEPI_00731 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
EDPEAEPI_00732 9.2e-73 S Psort location CytoplasmicMembrane, score
EDPEAEPI_00733 2.8e-64 S Domain of unknown function (DUF4430)
EDPEAEPI_00734 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EDPEAEPI_00735 2.1e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
EDPEAEPI_00736 1.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EDPEAEPI_00737 2.9e-164 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EDPEAEPI_00738 4.6e-104 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
EDPEAEPI_00739 1.1e-89 dps P Belongs to the Dps family
EDPEAEPI_00740 1.7e-78 perR P Belongs to the Fur family
EDPEAEPI_00741 7.1e-27 yqgQ S protein conserved in bacteria
EDPEAEPI_00742 7.8e-177 glk 2.7.1.2 G Glucokinase
EDPEAEPI_00743 0.0 typA T GTP-binding protein TypA
EDPEAEPI_00745 1.8e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EDPEAEPI_00746 2.1e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EDPEAEPI_00747 4.1e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EDPEAEPI_00748 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EDPEAEPI_00749 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EDPEAEPI_00750 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EDPEAEPI_00751 2.2e-86 sepF D cell septum assembly
EDPEAEPI_00752 2.9e-30 yggT D integral membrane protein
EDPEAEPI_00753 1.9e-144 ylmH S conserved protein, contains S4-like domain
EDPEAEPI_00754 8.4e-138 divIVA D Cell division initiation protein
EDPEAEPI_00755 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EDPEAEPI_00756 2.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDPEAEPI_00757 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDPEAEPI_00758 2.2e-34 nrdH O Glutaredoxin
EDPEAEPI_00759 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EDPEAEPI_00760 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EDPEAEPI_00761 2.8e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
EDPEAEPI_00762 3e-38 ptsH G phosphocarrier protein Hpr
EDPEAEPI_00763 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EDPEAEPI_00764 3.7e-227 L Transposase
EDPEAEPI_00765 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EDPEAEPI_00766 7.9e-162 XK27_05670 S Putative esterase
EDPEAEPI_00767 2.7e-153 XK27_05675 S Esterase
EDPEAEPI_00768 1.9e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
EDPEAEPI_00769 2.3e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
EDPEAEPI_00770 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
EDPEAEPI_00771 0.0 uup S abc transporter atp-binding protein
EDPEAEPI_00772 1.6e-39 MA20_06245 S yiaA/B two helix domain
EDPEAEPI_00773 1.7e-131 pip 1.11.1.10 S Alpha beta hydrolase
EDPEAEPI_00774 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EDPEAEPI_00775 1.1e-149 cobQ S glutamine amidotransferase
EDPEAEPI_00776 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EDPEAEPI_00777 6.1e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EDPEAEPI_00778 3.5e-161 ybbR S Protein conserved in bacteria
EDPEAEPI_00779 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EDPEAEPI_00780 1.3e-64 gtrA S GtrA-like protein
EDPEAEPI_00781 3.4e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
EDPEAEPI_00782 4.9e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EDPEAEPI_00783 2.8e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
EDPEAEPI_00784 3.3e-200 yurR 1.4.5.1 E oxidoreductase
EDPEAEPI_00785 1.2e-255 S phospholipase Carboxylesterase
EDPEAEPI_00786 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EDPEAEPI_00787 9.2e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EDPEAEPI_00788 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EDPEAEPI_00790 2.2e-30 KT response to antibiotic
EDPEAEPI_00791 5.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
EDPEAEPI_00792 1.2e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
EDPEAEPI_00793 1.5e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EDPEAEPI_00794 5.1e-116 ylfI S tigr01906
EDPEAEPI_00795 2.3e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EDPEAEPI_00796 2.8e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EDPEAEPI_00797 2.7e-59 XK27_08085
EDPEAEPI_00798 5.9e-194 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EDPEAEPI_00799 1.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EDPEAEPI_00800 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EDPEAEPI_00801 1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EDPEAEPI_00802 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EDPEAEPI_00803 3.4e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EDPEAEPI_00804 2e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EDPEAEPI_00805 3.6e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EDPEAEPI_00806 3e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EDPEAEPI_00807 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
EDPEAEPI_00809 2.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
EDPEAEPI_00810 4.1e-144 P molecular chaperone
EDPEAEPI_00811 1.2e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
EDPEAEPI_00812 5.7e-178 XK27_08075 M glycosyl transferase family 2
EDPEAEPI_00813 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_00814 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_00815 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_00816 1.9e-227 rodA D Belongs to the SEDS family
EDPEAEPI_00817 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EDPEAEPI_00818 7.6e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDPEAEPI_00819 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EDPEAEPI_00820 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDPEAEPI_00821 8e-67 GnaT 2.5.1.16 K acetyltransferase
EDPEAEPI_00822 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EDPEAEPI_00823 6.4e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EDPEAEPI_00824 1.6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EDPEAEPI_00825 1.3e-125 dnaD
EDPEAEPI_00826 1.9e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EDPEAEPI_00828 2.5e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDPEAEPI_00829 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDPEAEPI_00830 9.3e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EDPEAEPI_00831 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EDPEAEPI_00832 8.3e-73 argR K Regulates arginine biosynthesis genes
EDPEAEPI_00833 1.3e-301 recN L May be involved in recombinational repair of damaged DNA
EDPEAEPI_00834 4.9e-143 DegV S DegV family
EDPEAEPI_00835 6.9e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
EDPEAEPI_00836 8.3e-94 ypmS S Protein conserved in bacteria
EDPEAEPI_00837 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EDPEAEPI_00839 8.9e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EDPEAEPI_00840 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EDPEAEPI_00841 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EDPEAEPI_00842 1.1e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EDPEAEPI_00843 3.5e-37 ysdA L Membrane
EDPEAEPI_00844 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDPEAEPI_00845 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDPEAEPI_00846 0.0 dnaE 2.7.7.7 L DNA polymerase
EDPEAEPI_00847 5.1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EDPEAEPI_00848 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EDPEAEPI_00849 2.5e-25 Q the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_00850 1.9e-234 Q the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_00851 1.7e-18 S Domain of unknown function (DUF4649)
EDPEAEPI_00852 4e-176 XK27_08835 S ABC transporter substrate binding protein
EDPEAEPI_00853 1.7e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EDPEAEPI_00854 8.9e-136 XK27_08845 S abc transporter atp-binding protein
EDPEAEPI_00855 5.1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDPEAEPI_00856 2.8e-148 estA CE1 S Esterase
EDPEAEPI_00857 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
EDPEAEPI_00858 4.8e-18 XK27_08880
EDPEAEPI_00859 1e-75 fld C Flavodoxin
EDPEAEPI_00860 2.9e-282 clcA P Chloride transporter, ClC family
EDPEAEPI_00861 5.8e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EDPEAEPI_00862 7.8e-214 XK27_05110 P Chloride transporter ClC family
EDPEAEPI_00863 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EDPEAEPI_00865 1.2e-165 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
EDPEAEPI_00867 1.3e-18 E Zn peptidase
EDPEAEPI_00868 5.7e-21
EDPEAEPI_00869 1.5e-24
EDPEAEPI_00870 1.6e-110 S DNA binding
EDPEAEPI_00871 7.1e-33
EDPEAEPI_00874 1.3e-76 M Pilin isopeptide linkage domain protein
EDPEAEPI_00876 7.7e-33 S ERF superfamily
EDPEAEPI_00877 7.6e-47 S Protein of unknown function (DUF1351)
EDPEAEPI_00878 7.7e-67 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDPEAEPI_00879 1.2e-74 S magnesium ion binding
EDPEAEPI_00881 4.3e-12 S YopX protein
EDPEAEPI_00886 5e-26 S Protein of unknown function (DUF1642)
EDPEAEPI_00888 2.3e-48 S sequence-specific DNA binding
EDPEAEPI_00891 7.6e-34 arpU S Transcriptional regulator, ArpU family
EDPEAEPI_00892 1.7e-195 S N-methyltransferase activity
EDPEAEPI_00893 1.8e-38
EDPEAEPI_00894 4.5e-238 S Terminase-like family
EDPEAEPI_00895 1.9e-251 S Phage portal protein, SPP1 Gp6-like
EDPEAEPI_00896 4.2e-116 S Phage Mu protein F like protein
EDPEAEPI_00897 1.3e-20 S Domain of unknown function (DUF4355)
EDPEAEPI_00898 2.6e-16
EDPEAEPI_00899 1.3e-177 S Phage major capsid protein E
EDPEAEPI_00901 8.1e-36 S Phage gp6-like head-tail connector protein
EDPEAEPI_00903 5.8e-42 S exonuclease activity
EDPEAEPI_00904 9.7e-62 S Protein of unknown function (DUF3168)
EDPEAEPI_00905 2.9e-74 S Phage major tail protein 2
EDPEAEPI_00906 8.3e-52 S Pfam:Phage_TAC_12
EDPEAEPI_00908 3.8e-202 S transmembrane transport
EDPEAEPI_00909 4.9e-197 S Phage tail protein
EDPEAEPI_00910 0.0 S peptidoglycan catabolic process
EDPEAEPI_00911 9.5e-201 S N-acetylmuramoyl-L-alanine amidase activity
EDPEAEPI_00914 1.2e-44
EDPEAEPI_00915 7.2e-27 hol S Holin, phage phi LC3 family
EDPEAEPI_00916 1.6e-07
EDPEAEPI_00919 4.4e-80 S peptidoglycan catabolic process
EDPEAEPI_00921 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
EDPEAEPI_00922 2.7e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EDPEAEPI_00923 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
EDPEAEPI_00924 2.7e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDPEAEPI_00925 5.6e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EDPEAEPI_00926 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EDPEAEPI_00927 3.5e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EDPEAEPI_00928 1.3e-144
EDPEAEPI_00929 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
EDPEAEPI_00930 3e-270 pelF GT4 M Domain of unknown function (DUF3492)
EDPEAEPI_00931 3.8e-183 pelG M Putative exopolysaccharide Exporter (EPS-E)
EDPEAEPI_00932 5.9e-223 cotH M CotH kinase protein
EDPEAEPI_00933 6e-97 P VTC domain
EDPEAEPI_00934 2e-83 S membrane
EDPEAEPI_00935 3.2e-134 G Domain of unknown function (DUF4832)
EDPEAEPI_00936 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDPEAEPI_00937 3.7e-11 S Protein of unknown function (DUF1146)
EDPEAEPI_00938 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDPEAEPI_00939 2.7e-25 epuA S DNA-directed RNA polymerase subunit beta
EDPEAEPI_00940 3.2e-153 endA F DNA RNA non-specific endonuclease
EDPEAEPI_00941 2.9e-111 tcyB_2 P ABC transporter (permease)
EDPEAEPI_00942 1.9e-116 gltJ P ABC transporter (Permease
EDPEAEPI_00943 1.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDPEAEPI_00944 6.9e-23 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_00945 2e-08 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_00946 8.6e-58 tcyB_2 P ABC transporter (permease)
EDPEAEPI_00947 1.9e-116 gltJ P ABC transporter (Permease
EDPEAEPI_00948 1.1e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDPEAEPI_00949 8.2e-40 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_00950 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDPEAEPI_00951 8.7e-235 vicK 2.7.13.3 T Histidine kinase
EDPEAEPI_00952 3.5e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EDPEAEPI_00953 1.5e-56 S Protein of unknown function (DUF454)
EDPEAEPI_00954 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EDPEAEPI_00955 7.8e-146 yidA S hydrolases of the HAD superfamily
EDPEAEPI_00956 7.8e-144 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
EDPEAEPI_00957 1e-66 ywiB S Domain of unknown function (DUF1934)
EDPEAEPI_00958 0.0 pacL 3.6.3.8 P cation transport ATPase
EDPEAEPI_00959 5.3e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EDPEAEPI_00960 1.8e-153 yjjH S Calcineurin-like phosphoesterase
EDPEAEPI_00961 1.5e-203 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EDPEAEPI_00962 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EDPEAEPI_00963 3.2e-124 ftsE D cell division ATP-binding protein FtsE
EDPEAEPI_00964 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EDPEAEPI_00965 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EDPEAEPI_00966 4.3e-177 yubA S permease
EDPEAEPI_00967 5e-221 G COG0457 FOG TPR repeat
EDPEAEPI_00968 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDPEAEPI_00969 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EDPEAEPI_00970 3.1e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EDPEAEPI_00971 8.6e-87 ebsA S Family of unknown function (DUF5322)
EDPEAEPI_00972 2.5e-17 M LysM domain
EDPEAEPI_00973 1.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EDPEAEPI_00974 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EDPEAEPI_00975 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EDPEAEPI_00976 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EDPEAEPI_00977 2.6e-85 XK27_03610 K Gnat family
EDPEAEPI_00978 1.2e-91 yybC
EDPEAEPI_00979 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EDPEAEPI_00980 2.2e-273 pepV 3.5.1.18 E Dipeptidase
EDPEAEPI_00981 1.1e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
EDPEAEPI_00982 9.1e-229 V Glucan-binding protein C
EDPEAEPI_00983 5.6e-253 V Glucan-binding protein C
EDPEAEPI_00984 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EDPEAEPI_00985 8.7e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EDPEAEPI_00986 2.7e-86 S Protein of unknown function (DUF1697)
EDPEAEPI_00987 4.7e-143 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EDPEAEPI_00988 1.8e-53 S LemA family
EDPEAEPI_00989 1.1e-167 clcA_2 P chloride
EDPEAEPI_00990 3.7e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
EDPEAEPI_00991 2.9e-131 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EDPEAEPI_00992 6.8e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EDPEAEPI_00993 8.9e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EDPEAEPI_00994 3.5e-110 cps4C M biosynthesis protein
EDPEAEPI_00995 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
EDPEAEPI_00996 1.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EDPEAEPI_00997 8.2e-221 rgpAc GT4 M group 1 family protein
EDPEAEPI_00998 3.4e-211 wcoF M Glycosyltransferase, group 1 family protein
EDPEAEPI_00999 4.9e-147
EDPEAEPI_01000 1.1e-162 M Glycosyltransferase, group 2 family protein
EDPEAEPI_01001 8.9e-152 M Glycosyltransferase like family 2
EDPEAEPI_01002 3.3e-174
EDPEAEPI_01003 1.6e-250 epsU S Polysaccharide biosynthesis protein
EDPEAEPI_01004 2e-159 S Acyltransferase family
EDPEAEPI_01005 7.7e-213 glf 5.4.99.9 M UDP-galactopyranose mutase
EDPEAEPI_01006 9.8e-183 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
EDPEAEPI_01007 9.1e-187 wbbI M transferase activity, transferring glycosyl groups
EDPEAEPI_01009 2.5e-152 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EDPEAEPI_01010 1.1e-107 pgm G Belongs to the phosphoglycerate mutase family
EDPEAEPI_01011 2.4e-107 G Belongs to the phosphoglycerate mutase family
EDPEAEPI_01012 1.1e-107 G Belongs to the phosphoglycerate mutase family
EDPEAEPI_01013 1.6e-197 S hmm pf01594
EDPEAEPI_01014 7.3e-288 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDPEAEPI_01015 4.9e-39 S granule-associated protein
EDPEAEPI_01016 1.4e-284 S unusual protein kinase
EDPEAEPI_01017 4.8e-103 estA E Lysophospholipase L1 and related esterases
EDPEAEPI_01018 8.7e-156 rssA S Phospholipase, patatin family
EDPEAEPI_01019 3.8e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EDPEAEPI_01020 2.1e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EDPEAEPI_01021 5.4e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EDPEAEPI_01022 6.6e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EDPEAEPI_01023 2.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EDPEAEPI_01024 0.0 S the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_01025 8.7e-224 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01026 2.2e-203 hpk9 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01027 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EDPEAEPI_01028 4.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EDPEAEPI_01029 1.3e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EDPEAEPI_01030 0.0 lpdA 1.8.1.4 C Dehydrogenase
EDPEAEPI_01031 0.0 3.5.1.28 NU amidase activity
EDPEAEPI_01032 1.4e-193 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
EDPEAEPI_01033 1e-108 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EDPEAEPI_01034 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDPEAEPI_01035 2.1e-144 ycdO P periplasmic lipoprotein involved in iron transport
EDPEAEPI_01036 5.3e-231 ycdB P peroxidase
EDPEAEPI_01037 3.8e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EDPEAEPI_01038 1.2e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EDPEAEPI_01039 3e-24 tatA U protein secretion
EDPEAEPI_01040 4.7e-213 msmX P Belongs to the ABC transporter superfamily
EDPEAEPI_01041 9.8e-152 malG P ABC transporter (Permease
EDPEAEPI_01042 2.2e-249 malF P ABC transporter (Permease
EDPEAEPI_01043 3.9e-229 malX G ABC transporter
EDPEAEPI_01044 2.1e-156 malR K Transcriptional regulator
EDPEAEPI_01045 1.1e-299 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EDPEAEPI_01046 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EDPEAEPI_01047 5.7e-38
EDPEAEPI_01048 7.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
EDPEAEPI_01049 3.3e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EDPEAEPI_01050 0.0 pepN 3.4.11.2 E aminopeptidase
EDPEAEPI_01051 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
EDPEAEPI_01052 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDPEAEPI_01053 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDPEAEPI_01054 1.5e-155 pstA P phosphate transport system permease
EDPEAEPI_01055 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
EDPEAEPI_01056 1.1e-156 pstS P phosphate
EDPEAEPI_01057 1.9e-250 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EDPEAEPI_01058 3.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EDPEAEPI_01059 1e-44 yktA S Belongs to the UPF0223 family
EDPEAEPI_01060 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EDPEAEPI_01061 5.1e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EDPEAEPI_01062 1.7e-148 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EDPEAEPI_01063 2.4e-240 XK27_04775 S hemerythrin HHE cation binding domain
EDPEAEPI_01064 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
EDPEAEPI_01065 1.8e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EDPEAEPI_01066 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EDPEAEPI_01067 6.8e-136 S haloacid dehalogenase-like hydrolase
EDPEAEPI_01068 2.5e-239 metY 2.5.1.49 E o-acetylhomoserine
EDPEAEPI_01069 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EDPEAEPI_01070 2.1e-241 agcS E (Alanine) symporter
EDPEAEPI_01071 2.3e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EDPEAEPI_01072 5.2e-173 bglC K Transcriptional regulator
EDPEAEPI_01073 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EDPEAEPI_01074 6.4e-82 yecS P ABC transporter (Permease
EDPEAEPI_01075 3.9e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
EDPEAEPI_01076 1.4e-238 nylA 3.5.1.4 J Belongs to the amidase family
EDPEAEPI_01077 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EDPEAEPI_01078 1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EDPEAEPI_01079 6.5e-103
EDPEAEPI_01080 3.8e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EDPEAEPI_01081 5.5e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EDPEAEPI_01082 9.4e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EDPEAEPI_01083 8e-135 S TraX protein
EDPEAEPI_01084 5.1e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EDPEAEPI_01085 4.6e-272 S Psort location CytoplasmicMembrane, score
EDPEAEPI_01086 1.1e-232 dinF V Mate efflux family protein
EDPEAEPI_01087 4.1e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
EDPEAEPI_01088 0.0 V Type III restriction enzyme, res subunit
EDPEAEPI_01089 7.9e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EDPEAEPI_01090 7e-242 S the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_01091 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EDPEAEPI_01092 4.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EDPEAEPI_01093 4.9e-157 czcD P cation diffusion facilitator family transporter
EDPEAEPI_01094 2.7e-94 K Transcriptional regulator, TetR family
EDPEAEPI_01095 1.2e-58 S Protein of unknown function with HXXEE motif
EDPEAEPI_01096 1.6e-36
EDPEAEPI_01097 4.8e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EDPEAEPI_01098 1.7e-151 I Alpha/beta hydrolase family
EDPEAEPI_01099 6e-180 1.1.1.1 C nadph quinone reductase
EDPEAEPI_01100 1.3e-67 K Transcriptional regulator
EDPEAEPI_01101 1.6e-61 pnuC H nicotinamide mononucleotide transporter
EDPEAEPI_01102 7.4e-149 cbiO2 P ABC transporter, ATP-binding protein
EDPEAEPI_01103 1e-156 P abc transporter atp-binding protein
EDPEAEPI_01104 2.8e-132 cbiQ P cobalt transport
EDPEAEPI_01105 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
EDPEAEPI_01106 2.7e-143 S Phenazine biosynthesis protein
EDPEAEPI_01107 7.5e-267 proWX P ABC transporter
EDPEAEPI_01108 1.5e-124 proV E abc transporter atp-binding protein
EDPEAEPI_01109 2.1e-150 C alcohol dehydrogenase
EDPEAEPI_01110 3.2e-64 mgrA K Transcriptional regulator, MarR family
EDPEAEPI_01111 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EDPEAEPI_01112 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EDPEAEPI_01115 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EDPEAEPI_01117 2.4e-136 IQ Acetoin reductase
EDPEAEPI_01118 3.1e-44 pspE P Rhodanese-like protein
EDPEAEPI_01119 4.2e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EDPEAEPI_01120 1.1e-222 XK27_05470 E Methionine synthase
EDPEAEPI_01121 3.6e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EDPEAEPI_01122 1.6e-239 T PhoQ Sensor
EDPEAEPI_01123 2.2e-122 KT Transcriptional regulatory protein, C terminal
EDPEAEPI_01124 3.4e-149 S TraX protein
EDPEAEPI_01125 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EDPEAEPI_01126 4e-153 dprA LU DNA protecting protein DprA
EDPEAEPI_01127 3.1e-10 GK ROK family
EDPEAEPI_01128 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDPEAEPI_01129 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EDPEAEPI_01130 5.3e-127 K DNA-binding helix-turn-helix protein
EDPEAEPI_01131 2.3e-90 niaR S small molecule binding protein (contains 3H domain)
EDPEAEPI_01132 2.7e-86
EDPEAEPI_01133 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EDPEAEPI_01134 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EDPEAEPI_01135 1.3e-125 gntR1 K transcriptional
EDPEAEPI_01136 6.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EDPEAEPI_01137 3e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EDPEAEPI_01138 7.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
EDPEAEPI_01139 1e-44
EDPEAEPI_01140 5.8e-51
EDPEAEPI_01141 4e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDPEAEPI_01142 1.8e-156 aatB ET ABC transporter substrate-binding protein
EDPEAEPI_01143 1.3e-111 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_01144 1.8e-105 artQ P ABC transporter (Permease
EDPEAEPI_01145 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
EDPEAEPI_01146 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EDPEAEPI_01147 2.9e-165 cpsY K Transcriptional regulator
EDPEAEPI_01148 5.5e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
EDPEAEPI_01149 3.9e-163 yeiH S Membrane
EDPEAEPI_01151 2.6e-09
EDPEAEPI_01152 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
EDPEAEPI_01153 2.2e-143 XK27_10720 D peptidase activity
EDPEAEPI_01154 9e-275 pepD E Dipeptidase
EDPEAEPI_01155 5.7e-161 whiA K May be required for sporulation
EDPEAEPI_01156 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EDPEAEPI_01157 1e-162 rapZ S Displays ATPase and GTPase activities
EDPEAEPI_01158 1.2e-132 yejC S cyclic nucleotide-binding protein
EDPEAEPI_01159 7.9e-165 D nuclear chromosome segregation
EDPEAEPI_01160 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EDPEAEPI_01161 9.3e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EDPEAEPI_01162 9.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
EDPEAEPI_01163 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EDPEAEPI_01164 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EDPEAEPI_01165 3.7e-19
EDPEAEPI_01166 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDPEAEPI_01167 4.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EDPEAEPI_01168 1.1e-81 ypmB S Protein conserved in bacteria
EDPEAEPI_01169 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EDPEAEPI_01170 8.1e-114 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EDPEAEPI_01171 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EDPEAEPI_01172 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
EDPEAEPI_01173 8.1e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EDPEAEPI_01174 3.2e-187 tcsA S membrane
EDPEAEPI_01175 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EDPEAEPI_01176 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EDPEAEPI_01177 1.9e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EDPEAEPI_01178 9.2e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
EDPEAEPI_01179 4.7e-171 coaA 2.7.1.33 F Pantothenic acid kinase
EDPEAEPI_01180 1e-29 rpsT J Binds directly to 16S ribosomal RNA
EDPEAEPI_01181 1.7e-241 T PhoQ Sensor
EDPEAEPI_01182 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDPEAEPI_01183 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EDPEAEPI_01184 3.5e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EDPEAEPI_01185 8.2e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EDPEAEPI_01186 2.7e-92 panT S ECF transporter, substrate-specific component
EDPEAEPI_01187 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EDPEAEPI_01188 1.6e-165 metF 1.5.1.20 E reductase
EDPEAEPI_01189 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EDPEAEPI_01191 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EDPEAEPI_01192 0.0 3.6.3.8 P cation transport ATPase
EDPEAEPI_01193 1.5e-239 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EDPEAEPI_01194 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDPEAEPI_01195 2.8e-235 dltB M Membrane protein involved in D-alanine export
EDPEAEPI_01196 8.4e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDPEAEPI_01197 0.0 XK27_10035 V abc transporter atp-binding protein
EDPEAEPI_01198 2.2e-291 yfiB1 V abc transporter atp-binding protein
EDPEAEPI_01199 4.1e-99 pvaA M lytic transglycosylase activity
EDPEAEPI_01200 1.4e-178 ndpA S 37-kD nucleoid-associated bacterial protein
EDPEAEPI_01201 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EDPEAEPI_01202 8.8e-102 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EDPEAEPI_01203 8.3e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EDPEAEPI_01204 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EDPEAEPI_01205 5.1e-110 tdk 2.7.1.21 F thymidine kinase
EDPEAEPI_01206 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EDPEAEPI_01207 4.9e-153 gst O Glutathione S-transferase
EDPEAEPI_01208 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EDPEAEPI_01209 3.5e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDPEAEPI_01210 4.4e-45 rpmE2 J 50S ribosomal protein L31
EDPEAEPI_01211 9.7e-203 mntH P Mn2 and Fe2 transporters of the NRAMP family
EDPEAEPI_01212 2.7e-16 mntH P Mn2 and Fe2 transporters of the NRAMP family
EDPEAEPI_01213 6.4e-163 ypuA S secreted protein
EDPEAEPI_01214 2e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EDPEAEPI_01215 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EDPEAEPI_01216 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDPEAEPI_01217 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EDPEAEPI_01218 7.8e-255 noxE P NADH oxidase
EDPEAEPI_01219 2.1e-293 yfmM S abc transporter atp-binding protein
EDPEAEPI_01220 2.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
EDPEAEPI_01221 5.9e-136 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EDPEAEPI_01222 9.4e-81 S ECF-type riboflavin transporter, S component
EDPEAEPI_01224 5.2e-213 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EDPEAEPI_01225 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EDPEAEPI_01227 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDPEAEPI_01228 1.5e-45 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDPEAEPI_01229 1.2e-36 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDPEAEPI_01230 1.9e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EDPEAEPI_01231 3.8e-22 WQ51_00220 K Helix-turn-helix domain
EDPEAEPI_01232 1.7e-83 S Protein of unknown function (DUF3278)
EDPEAEPI_01233 0.0 smc D Required for chromosome condensation and partitioning
EDPEAEPI_01234 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EDPEAEPI_01235 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EDPEAEPI_01236 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EDPEAEPI_01237 8.8e-124 alkD L DNA alkylation repair enzyme
EDPEAEPI_01238 6.3e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EDPEAEPI_01239 5.2e-87 pat 2.3.1.183 M acetyltransferase
EDPEAEPI_01240 8.1e-263 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EDPEAEPI_01241 2.4e-49 L COG1943 Transposase and inactivated derivatives
EDPEAEPI_01242 1.2e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EDPEAEPI_01243 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EDPEAEPI_01244 4.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EDPEAEPI_01245 3.9e-119 sdaAB 4.3.1.17 E L-serine dehydratase
EDPEAEPI_01246 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
EDPEAEPI_01247 5.6e-124 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
EDPEAEPI_01248 4e-124 tktN 2.2.1.1 G Transketolase
EDPEAEPI_01249 1.4e-219 ulaA 2.7.1.194 S PTS system sugar-specific permease component
EDPEAEPI_01250 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
EDPEAEPI_01251 8e-224 2.7.1.194, 2.7.1.202, 2.7.1.204 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EDPEAEPI_01252 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
EDPEAEPI_01253 1.1e-79 3.4.21.89 S RDD family
EDPEAEPI_01254 3.5e-99 Z012_04635 K sequence-specific DNA binding
EDPEAEPI_01255 2.7e-48 L COG1943 Transposase and inactivated derivatives
EDPEAEPI_01256 6.5e-158 S dextransucrase activity
EDPEAEPI_01257 1.1e-265 M Putative cell wall binding repeat
EDPEAEPI_01258 8.2e-136 S dextransucrase activity
EDPEAEPI_01259 0.0 M Putative cell wall binding repeat
EDPEAEPI_01260 3.1e-151 V ABC transporter
EDPEAEPI_01261 2.5e-15 D CobQ CobB MinD ParA nucleotide binding domain protein
EDPEAEPI_01262 3e-104 S ABC-2 family transporter protein
EDPEAEPI_01263 3.7e-129
EDPEAEPI_01264 1.3e-117 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
EDPEAEPI_01265 2.3e-31 bcrA V abc transporter atp-binding protein
EDPEAEPI_01266 1.4e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDPEAEPI_01267 1.6e-239 T PhoQ Sensor
EDPEAEPI_01268 1.1e-87
EDPEAEPI_01269 1.8e-78 K Acetyltransferase (GNAT) domain
EDPEAEPI_01270 2.8e-80
EDPEAEPI_01271 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDPEAEPI_01272 1.3e-188 desK 2.7.13.3 T Histidine kinase
EDPEAEPI_01273 2.8e-134 yvfS V ABC-2 type transporter
EDPEAEPI_01274 9.7e-158 XK27_09825 V abc transporter atp-binding protein
EDPEAEPI_01277 3.9e-165 yocS S Transporter
EDPEAEPI_01278 1.3e-81 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
EDPEAEPI_01279 1.3e-131 yvfS V Transporter
EDPEAEPI_01280 1e-154 XK27_09825 V abc transporter atp-binding protein
EDPEAEPI_01281 1.6e-14 liaI KT membrane
EDPEAEPI_01282 7.6e-30 liaI KT membrane
EDPEAEPI_01283 6.1e-93 XK27_05000 S metal cluster binding
EDPEAEPI_01284 0.0 V ABC transporter (permease)
EDPEAEPI_01285 2.1e-132 macB2 V ABC transporter, ATP-binding protein
EDPEAEPI_01286 2.5e-162 T Histidine kinase
EDPEAEPI_01287 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDPEAEPI_01288 2e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EDPEAEPI_01289 1.3e-219 pbuX F xanthine permease
EDPEAEPI_01290 1.2e-275 V (ABC) transporter
EDPEAEPI_01291 2.2e-151 K sequence-specific DNA binding
EDPEAEPI_01292 5.1e-243 norM V Multidrug efflux pump
EDPEAEPI_01294 4.8e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDPEAEPI_01295 7.4e-14
EDPEAEPI_01296 1.8e-30 T DNase/tRNase domain of colicin-like bacteriocin
EDPEAEPI_01297 0.0 S Domain of unknown function DUF87
EDPEAEPI_01298 7.4e-131 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EDPEAEPI_01299 2.9e-230 brnQ E Component of the transport system for branched-chain amino acids
EDPEAEPI_01300 2.3e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDPEAEPI_01301 2e-58 S Protein of unknown function (DUF3290)
EDPEAEPI_01302 3e-100 S Protein of unknown function (DUF421)
EDPEAEPI_01303 5.9e-15 csbD K CsbD-like
EDPEAEPI_01304 3.2e-103 S Carbohydrate-binding domain-containing protein Cthe_2159
EDPEAEPI_01305 5.7e-37 XK27_01300 S ASCH
EDPEAEPI_01306 2.2e-212 yfnA E amino acid
EDPEAEPI_01307 0.0 S dextransucrase activity
EDPEAEPI_01308 2.8e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EDPEAEPI_01309 1.5e-42 S Sugar efflux transporter for intercellular exchange
EDPEAEPI_01310 2.2e-202 P FtsX-like permease family
EDPEAEPI_01311 1.5e-121 V abc transporter atp-binding protein
EDPEAEPI_01312 5.8e-95 K WHG domain
EDPEAEPI_01313 8.8e-170 ydhF S Aldo keto reductase
EDPEAEPI_01314 1.1e-06 S Protein of unknown function (DUF3169)
EDPEAEPI_01315 5.5e-27 XK27_07105 K transcriptional
EDPEAEPI_01316 9.7e-36
EDPEAEPI_01317 6.3e-108 XK27_02070 S nitroreductase
EDPEAEPI_01318 2e-152 1.13.11.2 S glyoxalase
EDPEAEPI_01319 4.3e-77 ywnA K Transcriptional regulator
EDPEAEPI_01320 5.9e-152 E Alpha/beta hydrolase of unknown function (DUF915)
EDPEAEPI_01321 1.1e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDPEAEPI_01322 3e-108 drgA C nitroreductase
EDPEAEPI_01323 1.6e-112 yoaK S Protein of unknown function (DUF1275)
EDPEAEPI_01324 5.3e-40 DJ nuclease activity
EDPEAEPI_01325 1.9e-30 XK27_10490
EDPEAEPI_01326 3.2e-158 yvgN C reductase
EDPEAEPI_01327 3.2e-209 S Tetratricopeptide repeat
EDPEAEPI_01328 0.0 lacL 3.2.1.23 G -beta-galactosidase
EDPEAEPI_01329 0.0 lacS G transporter
EDPEAEPI_01330 3.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EDPEAEPI_01331 1.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDPEAEPI_01332 3.3e-283 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDPEAEPI_01333 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EDPEAEPI_01334 1.2e-151 galR K Transcriptional regulator
EDPEAEPI_01335 4.9e-301 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
EDPEAEPI_01336 1e-224 vncS 2.7.13.3 T Histidine kinase
EDPEAEPI_01337 5.2e-116 K Response regulator receiver domain protein
EDPEAEPI_01338 2.3e-238 vex3 V Efflux ABC transporter, permease protein
EDPEAEPI_01339 1.9e-107 vex2 V abc transporter atp-binding protein
EDPEAEPI_01340 1.7e-211 vex1 V Efflux ABC transporter, permease protein
EDPEAEPI_01341 5e-284 XK27_07020 S Belongs to the UPF0371 family
EDPEAEPI_01343 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
EDPEAEPI_01344 1e-179 XK27_10475 S oxidoreductase
EDPEAEPI_01345 5.7e-59 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
EDPEAEPI_01346 6.9e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
EDPEAEPI_01347 8e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
EDPEAEPI_01348 7.7e-225 thrE K Psort location CytoplasmicMembrane, score
EDPEAEPI_01349 0.0 M Putative cell wall binding repeat
EDPEAEPI_01350 5.4e-34 S Immunity protein 41
EDPEAEPI_01351 0.0 pepO 3.4.24.71 O Peptidase family M13
EDPEAEPI_01352 9e-08 S Enterocin A Immunity
EDPEAEPI_01353 3.8e-190 mccF V LD-carboxypeptidase
EDPEAEPI_01356 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
EDPEAEPI_01357 9.4e-114 yhfC S Putative membrane peptidase family (DUF2324)
EDPEAEPI_01359 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_01361 2e-235 S dextransucrase activity
EDPEAEPI_01362 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_01363 2.3e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EDPEAEPI_01364 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EDPEAEPI_01365 2.5e-78 S dextransucrase activity
EDPEAEPI_01366 1.1e-20 S dextransucrase activity
EDPEAEPI_01367 0.0 S dextransucrase activity
EDPEAEPI_01368 0.0 M Putative cell wall binding repeat
EDPEAEPI_01369 1.5e-65 M Putative cell wall binding repeat
EDPEAEPI_01370 1e-82 M Putative cell wall binding repeat
EDPEAEPI_01372 3.2e-133 XK27_00785 S CAAX protease self-immunity
EDPEAEPI_01373 3.4e-234 EGP Major facilitator Superfamily
EDPEAEPI_01374 2.2e-64 rmaI K Transcriptional regulator, MarR family
EDPEAEPI_01375 5.9e-92 maa 2.3.1.79 GK Maltose O-acetyltransferase
EDPEAEPI_01376 5.8e-64 2.7.13.3 T Histidine kinase
EDPEAEPI_01377 2.5e-73 K Transcriptional regulatory protein, C terminal
EDPEAEPI_01379 2.2e-15
EDPEAEPI_01380 4.3e-87 V abc transporter atp-binding protein
EDPEAEPI_01381 2.3e-53 S Bacterial protein of unknown function (DUF961)
EDPEAEPI_01382 1e-63 S Bacterial protein of unknown function (DUF961)
EDPEAEPI_01383 3.7e-265 D Domain of unknown function DUF87
EDPEAEPI_01384 1.6e-232 K Replication initiation factor
EDPEAEPI_01385 1.9e-30 S Psort location CytoplasmicMembrane, score
EDPEAEPI_01386 7.5e-91 S Antirestriction protein (ArdA)
EDPEAEPI_01387 3.8e-90 S TcpE family
EDPEAEPI_01388 0.0 S AAA-like domain
EDPEAEPI_01389 0.0 S the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_01390 2.2e-190 yddH M NlpC p60 family protein
EDPEAEPI_01391 4.8e-168 S Conjugative transposon protein TcpC
EDPEAEPI_01392 0.0 tetP J elongation factor G
EDPEAEPI_01393 2.4e-134 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
EDPEAEPI_01394 1.6e-16
EDPEAEPI_01395 5.6e-95 L Resolvase, N terminal domain
EDPEAEPI_01396 0.0 L Transposase and inactivated derivatives, TnpA family
EDPEAEPI_01397 3.9e-37 K Helix-turn-helix domain
EDPEAEPI_01398 1.1e-71 phyR K Sigma-70, region 4
EDPEAEPI_01399 9.3e-36 S Helix-turn-helix domain
EDPEAEPI_01400 1.8e-30 xis S Excisionase from transposon Tn916
EDPEAEPI_01401 1.3e-232 L DNA binding domain of tn916 integrase
EDPEAEPI_01403 2.3e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
EDPEAEPI_01404 0.0 3.5.1.28 M domain protein
EDPEAEPI_01405 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
EDPEAEPI_01406 3.3e-21
EDPEAEPI_01410 9.4e-10 sraP UW domain, Protein
EDPEAEPI_01412 9e-102 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
EDPEAEPI_01413 9.7e-124 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
EDPEAEPI_01414 1.6e-185 nss M transferase activity, transferring glycosyl groups
EDPEAEPI_01415 3.6e-16 S Accessory secretory protein Sec, Asp5
EDPEAEPI_01416 2.6e-17 S Accessory secretory protein Sec Asp4
EDPEAEPI_01417 7.9e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EDPEAEPI_01418 3.7e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EDPEAEPI_01419 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EDPEAEPI_01420 3.8e-78 asp3 S Accessory Sec system protein Asp3
EDPEAEPI_01421 5.8e-291 asp2 3.4.11.5 S Accessory Sec system protein Asp2
EDPEAEPI_01422 3.2e-289 asp1 S Accessory Sec system protein Asp1
EDPEAEPI_01423 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
EDPEAEPI_01424 0.0 M family 8
EDPEAEPI_01425 0.0 sbcC L ATPase involved in DNA repair
EDPEAEPI_01426 1.1e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EDPEAEPI_01427 0.0 GM domain, Protein
EDPEAEPI_01428 0.0 zmpB M signal peptide protein, YSIRK family
EDPEAEPI_01429 6e-249 fhaB M Rib/alpha-like repeat
EDPEAEPI_01430 0.0 M domain protein
EDPEAEPI_01431 1.3e-30 M Pilin isopeptide linkage domain protein
EDPEAEPI_01432 2.4e-141 M domain protein
EDPEAEPI_01433 9.4e-287 M Pilin isopeptide linkage domain protein
EDPEAEPI_01434 6e-280 G mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
EDPEAEPI_01435 3.7e-10
EDPEAEPI_01436 2.7e-184 XK27_10075 S abc transporter atp-binding protein
EDPEAEPI_01437 6.9e-215 L Transposase IS116 IS110 IS902
EDPEAEPI_01438 1.4e-209 V abc transporter atp-binding protein
EDPEAEPI_01439 8e-297 V abc transporter atp-binding protein
EDPEAEPI_01440 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EDPEAEPI_01442 7.4e-283 S Protein of unknown function (DUF3114)
EDPEAEPI_01443 1.1e-98 2.3.1.128 K Acetyltransferase GNAT Family
EDPEAEPI_01444 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EDPEAEPI_01445 1.8e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
EDPEAEPI_01446 1.2e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
EDPEAEPI_01447 6.4e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EDPEAEPI_01448 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EDPEAEPI_01449 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDPEAEPI_01450 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EDPEAEPI_01451 3.3e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EDPEAEPI_01452 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EDPEAEPI_01453 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EDPEAEPI_01456 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDPEAEPI_01457 1.9e-170 vraS 2.7.13.3 T Histidine kinase
EDPEAEPI_01458 1.7e-117 yvqF S Membrane
EDPEAEPI_01459 4.1e-104 kcsA P Ion transport protein
EDPEAEPI_01460 1.8e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
EDPEAEPI_01461 1.3e-134 stp 3.1.3.16 T phosphatase
EDPEAEPI_01462 2.7e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EDPEAEPI_01463 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EDPEAEPI_01464 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EDPEAEPI_01465 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EDPEAEPI_01466 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EDPEAEPI_01467 3.3e-192 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EDPEAEPI_01468 1.8e-142 XK27_02985 S overlaps another CDS with the same product name
EDPEAEPI_01469 3.2e-144 supH S overlaps another CDS with the same product name
EDPEAEPI_01470 7.3e-62 yvoA_1 K Transcriptional
EDPEAEPI_01471 7e-119 skfE V abc transporter atp-binding protein
EDPEAEPI_01472 5.3e-115 V ATPase activity
EDPEAEPI_01473 3.1e-170 oppF P Belongs to the ABC transporter superfamily
EDPEAEPI_01474 3e-201 oppD P Belongs to the ABC transporter superfamily
EDPEAEPI_01475 3.8e-165 amiD P ABC transporter (Permease
EDPEAEPI_01476 1.1e-273 amiC P ABC transporter (Permease
EDPEAEPI_01477 5.5e-311 amiA E ABC transporter, substrate-binding protein, family 5
EDPEAEPI_01478 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EDPEAEPI_01479 1.1e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EDPEAEPI_01480 4.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EDPEAEPI_01481 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EDPEAEPI_01482 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EDPEAEPI_01483 5.4e-101 yjbK S Adenylate cyclase
EDPEAEPI_01484 1.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDPEAEPI_01485 2.5e-203 iscS 2.8.1.7 E Cysteine desulfurase
EDPEAEPI_01486 8.2e-60 XK27_04120 S Putative amino acid metabolism
EDPEAEPI_01487 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EDPEAEPI_01488 1.5e-129 puuD T peptidase C26
EDPEAEPI_01489 2.4e-119 radC E Belongs to the UPF0758 family
EDPEAEPI_01490 7.1e-279 rgpF M Rhamnan synthesis protein F
EDPEAEPI_01491 3.1e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EDPEAEPI_01492 3.4e-141 rgpC GM Transport permease protein
EDPEAEPI_01493 1.6e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
EDPEAEPI_01494 2.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
EDPEAEPI_01495 9e-218 GT4 M transferase activity, transferring glycosyl groups
EDPEAEPI_01496 1.8e-218 M Psort location CytoplasmicMembrane, score
EDPEAEPI_01497 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
EDPEAEPI_01498 3.7e-227 L Transposase
EDPEAEPI_01499 6.6e-91 S Psort location CytoplasmicMembrane, score
EDPEAEPI_01500 6.5e-150 2.4.1.60 S Glycosyltransferase group 2 family protein
EDPEAEPI_01501 1.9e-43 S Uncharacterized conserved protein (DUF2304)
EDPEAEPI_01502 7e-127 arnC M group 2 family protein
EDPEAEPI_01503 3.9e-176 cpsIaJ S Glycosyltransferase like family 2
EDPEAEPI_01504 2.2e-155 M Glycosyltransferase, group 2 family protein
EDPEAEPI_01505 5.4e-226 amrA S membrane protein involved in the export of O-antigen and teichoic acid
EDPEAEPI_01506 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EDPEAEPI_01507 3.9e-260 S Glucosyl transferase GtrII
EDPEAEPI_01508 1.8e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EDPEAEPI_01509 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EDPEAEPI_01510 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EDPEAEPI_01511 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EDPEAEPI_01512 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EDPEAEPI_01513 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EDPEAEPI_01514 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
EDPEAEPI_01515 4.1e-198 arcT 2.6.1.1 E Aminotransferase
EDPEAEPI_01516 9.4e-136 ET Belongs to the bacterial solute-binding protein 3 family
EDPEAEPI_01517 3.2e-139 ET ABC transporter
EDPEAEPI_01518 1.1e-80 mutT 3.6.1.55 F Nudix family
EDPEAEPI_01519 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EDPEAEPI_01521 1.2e-161 S CAAX amino terminal protease family protein
EDPEAEPI_01522 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EDPEAEPI_01523 1.6e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_01524 1.7e-17 XK27_00735
EDPEAEPI_01525 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EDPEAEPI_01527 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDPEAEPI_01528 5.7e-10 O ADP-ribosylglycohydrolase
EDPEAEPI_01529 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
EDPEAEPI_01530 1.7e-60 ycaO O OsmC-like protein
EDPEAEPI_01532 2.2e-149 EG Permeases of the drug metabolite transporter (DMT) superfamily
EDPEAEPI_01533 6.5e-08 N PFAM Uncharacterised protein family UPF0150
EDPEAEPI_01534 3.9e-103 csn2 S CRISPR-associated protein (Cas_Csn2)
EDPEAEPI_01535 3.2e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDPEAEPI_01536 1.2e-160 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDPEAEPI_01537 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EDPEAEPI_01538 6.5e-111 serB 3.1.3.3 E phosphoserine phosphatase
EDPEAEPI_01539 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EDPEAEPI_01540 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDPEAEPI_01541 8.7e-96 3.1.3.18 S IA, variant 1
EDPEAEPI_01542 1.9e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EDPEAEPI_01543 2.2e-55 lrgA S Effector of murein hydrolase LrgA
EDPEAEPI_01545 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
EDPEAEPI_01546 9.2e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EDPEAEPI_01547 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDPEAEPI_01548 3.1e-101 wecD M Acetyltransferase (GNAT) domain
EDPEAEPI_01549 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EDPEAEPI_01550 2.3e-151 GK ROK family
EDPEAEPI_01551 2.6e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
EDPEAEPI_01552 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
EDPEAEPI_01553 1.3e-204 potD P spermidine putrescine ABC transporter
EDPEAEPI_01554 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
EDPEAEPI_01555 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
EDPEAEPI_01556 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EDPEAEPI_01557 1.4e-167 murB 1.3.1.98 M cell wall formation
EDPEAEPI_01558 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EDPEAEPI_01559 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EDPEAEPI_01560 1.7e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EDPEAEPI_01561 3.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EDPEAEPI_01562 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
EDPEAEPI_01563 0.0 ydaO E amino acid
EDPEAEPI_01564 8.8e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDPEAEPI_01565 1.5e-36 ylqC L Belongs to the UPF0109 family
EDPEAEPI_01566 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EDPEAEPI_01568 5.6e-210 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01569 4.2e-122 agrA KT phosphorelay signal transduction system
EDPEAEPI_01570 3.2e-165 O protein import
EDPEAEPI_01571 9.6e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EDPEAEPI_01572 2.9e-17 yjdB S Domain of unknown function (DUF4767)
EDPEAEPI_01573 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EDPEAEPI_01575 6.9e-158 xth 3.1.11.2 L exodeoxyribonuclease III
EDPEAEPI_01576 3.4e-72 S QueT transporter
EDPEAEPI_01578 5e-171 yfjR K regulation of single-species biofilm formation
EDPEAEPI_01580 8.4e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EDPEAEPI_01581 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EDPEAEPI_01582 2.8e-85 ccl S cog cog4708
EDPEAEPI_01583 3.1e-162 rbn E Belongs to the UPF0761 family
EDPEAEPI_01584 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EDPEAEPI_01585 6.6e-232 ytoI K transcriptional regulator containing CBS domains
EDPEAEPI_01586 3.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EDPEAEPI_01587 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDPEAEPI_01588 0.0 comEC S Competence protein ComEC
EDPEAEPI_01589 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EDPEAEPI_01590 2.9e-142 plsC 2.3.1.51 I Acyltransferase
EDPEAEPI_01591 8.1e-147 nodB3 G Polysaccharide deacetylase
EDPEAEPI_01592 3.5e-140 yabB 2.1.1.223 L Methyltransferase
EDPEAEPI_01593 6.6e-41 yazA L endonuclease containing a URI domain
EDPEAEPI_01594 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EDPEAEPI_01595 1.6e-152 corA P CorA-like protein
EDPEAEPI_01596 3.3e-62 yjqA S Bacterial PH domain
EDPEAEPI_01597 1.7e-99 thiT S Thiamine transporter
EDPEAEPI_01598 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EDPEAEPI_01599 7.6e-115 ywaF S Integral membrane protein (intg_mem_TP0381)
EDPEAEPI_01600 6.6e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EDPEAEPI_01605 3.3e-155 cjaA ET ABC transporter substrate-binding protein
EDPEAEPI_01606 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_01607 4.6e-107 P ABC transporter (Permease
EDPEAEPI_01608 6.6e-114 papP P ABC transporter (Permease
EDPEAEPI_01609 3.5e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EDPEAEPI_01610 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
EDPEAEPI_01611 0.0 copA 3.6.3.54 P P-type ATPase
EDPEAEPI_01612 6.8e-72 copY K negative regulation of transcription, DNA-templated
EDPEAEPI_01613 7.8e-163 EGP Major facilitator Superfamily
EDPEAEPI_01616 1.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EDPEAEPI_01617 3.2e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EDPEAEPI_01618 3.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EDPEAEPI_01619 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EDPEAEPI_01620 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EDPEAEPI_01621 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EDPEAEPI_01622 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EDPEAEPI_01623 4.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
EDPEAEPI_01624 1.1e-57
EDPEAEPI_01625 0.0 ctpE P E1-E2 ATPase
EDPEAEPI_01626 9e-47
EDPEAEPI_01627 1.5e-49
EDPEAEPI_01628 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EDPEAEPI_01630 1.9e-124 V abc transporter atp-binding protein
EDPEAEPI_01631 0.0 V ABC transporter (Permease
EDPEAEPI_01632 3.1e-125 K transcriptional regulator, MerR family
EDPEAEPI_01633 3.2e-104 dnaQ 2.7.7.7 L DNA polymerase III
EDPEAEPI_01634 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
EDPEAEPI_01635 9.6e-64 XK27_02560 S cog cog2151
EDPEAEPI_01636 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDPEAEPI_01637 1.4e-220 ytfP S Flavoprotein
EDPEAEPI_01639 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EDPEAEPI_01640 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
EDPEAEPI_01641 1.2e-175 ecsB U Bacterial ABC transporter protein EcsB
EDPEAEPI_01642 1.4e-130 ecsA V abc transporter atp-binding protein
EDPEAEPI_01643 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EDPEAEPI_01644 4.3e-09
EDPEAEPI_01646 1.5e-50
EDPEAEPI_01647 7.7e-11
EDPEAEPI_01648 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EDPEAEPI_01649 1.1e-43 yoeB S Addiction module toxin, Txe YoeB family
EDPEAEPI_01650 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EDPEAEPI_01651 5.7e-200 ylbM S Belongs to the UPF0348 family
EDPEAEPI_01652 4.9e-139 yqeM Q Methyltransferase domain protein
EDPEAEPI_01653 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EDPEAEPI_01654 3e-87 entB 3.5.1.19 Q Isochorismatase family
EDPEAEPI_01655 7.6e-106 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EDPEAEPI_01656 3.8e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EDPEAEPI_01657 7.7e-49 yhbY J RNA-binding protein
EDPEAEPI_01658 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EDPEAEPI_01659 5.1e-98 yqeG S hydrolase of the HAD superfamily
EDPEAEPI_01660 8.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EDPEAEPI_01661 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EDPEAEPI_01662 1.1e-60
EDPEAEPI_01663 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDPEAEPI_01664 1.5e-57
EDPEAEPI_01665 8.5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
EDPEAEPI_01666 2.2e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
EDPEAEPI_01667 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
EDPEAEPI_01668 7.2e-31 S PQ loop repeat
EDPEAEPI_01669 1.2e-36 S Sulfite exporter TauE/SafE
EDPEAEPI_01670 2.7e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDPEAEPI_01672 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDPEAEPI_01673 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EDPEAEPI_01674 5.3e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDPEAEPI_01675 3.1e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EDPEAEPI_01676 1.6e-188 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EDPEAEPI_01677 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
EDPEAEPI_01678 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
EDPEAEPI_01679 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDPEAEPI_01680 8.3e-99 pncA Q isochorismatase
EDPEAEPI_01681 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EDPEAEPI_01682 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EDPEAEPI_01683 9e-75 XK27_03180 T universal stress protein
EDPEAEPI_01685 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDPEAEPI_01686 7.4e-10 MU outer membrane autotransporter barrel domain protein
EDPEAEPI_01687 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EDPEAEPI_01688 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EDPEAEPI_01689 0.0 yjcE P NhaP-type Na H and K H antiporters
EDPEAEPI_01691 2.7e-97 ytqB J (SAM)-dependent
EDPEAEPI_01692 5.4e-183 yhcC S radical SAM protein
EDPEAEPI_01693 9.3e-187 ylbL T Belongs to the peptidase S16 family
EDPEAEPI_01694 7.3e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EDPEAEPI_01695 5.6e-92 rsmD 2.1.1.171 L Methyltransferase
EDPEAEPI_01696 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EDPEAEPI_01697 5e-10 S Protein of unknown function (DUF4059)
EDPEAEPI_01698 4.7e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
EDPEAEPI_01699 2e-161 yxeN P ABC transporter (Permease
EDPEAEPI_01700 3.7e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDPEAEPI_01701 6.1e-35
EDPEAEPI_01702 1.3e-190 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDPEAEPI_01703 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EDPEAEPI_01704 1e-142 cah 4.2.1.1 P carbonic anhydrase
EDPEAEPI_01705 3.4e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDPEAEPI_01708 2.9e-168 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EDPEAEPI_01709 4.6e-140 cppA E CppA N-terminal
EDPEAEPI_01710 3.1e-92 V CAAX protease self-immunity
EDPEAEPI_01711 5.2e-156 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EDPEAEPI_01712 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EDPEAEPI_01713 3.1e-44 spiA K sequence-specific DNA binding
EDPEAEPI_01722 0.0 mdlB V abc transporter atp-binding protein
EDPEAEPI_01723 0.0 mdlA V abc transporter atp-binding protein
EDPEAEPI_01726 7.5e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
EDPEAEPI_01727 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EDPEAEPI_01728 1.8e-61 yutD J protein conserved in bacteria
EDPEAEPI_01729 7.6e-258 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EDPEAEPI_01730 1.4e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EDPEAEPI_01731 5.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EDPEAEPI_01732 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EDPEAEPI_01733 4e-45 ftsL D cell division protein FtsL
EDPEAEPI_01734 5.2e-182 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EDPEAEPI_01735 1.5e-96
EDPEAEPI_01737 1.5e-49 yhaI J Protein of unknown function (DUF805)
EDPEAEPI_01738 3.8e-61 yhaI J Protein of unknown function (DUF805)
EDPEAEPI_01739 3.4e-54 yhaI S Protein of unknown function (DUF805)
EDPEAEPI_01740 7.9e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EDPEAEPI_01741 2.8e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EDPEAEPI_01742 1.1e-284 XK27_00765
EDPEAEPI_01743 4e-133 ecsA_2 V abc transporter atp-binding protein
EDPEAEPI_01744 4e-125 S Protein of unknown function (DUF554)
EDPEAEPI_01745 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EDPEAEPI_01746 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EDPEAEPI_01747 1.2e-236 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01748 2.5e-226 dcuS 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01749 6.8e-14
EDPEAEPI_01752 2.9e-145 V Psort location CytoplasmicMembrane, score
EDPEAEPI_01754 1.7e-298 O MreB/Mbl protein
EDPEAEPI_01755 4.8e-120 liaI S membrane
EDPEAEPI_01756 2e-74 XK27_02470 K LytTr DNA-binding domain protein
EDPEAEPI_01757 0.0 KT response to antibiotic
EDPEAEPI_01758 1e-117 yebC M Membrane
EDPEAEPI_01759 6.8e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
EDPEAEPI_01760 8e-171 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EDPEAEPI_01762 2.9e-31 yozG K Transcriptional regulator
EDPEAEPI_01766 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EDPEAEPI_01767 5.4e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EDPEAEPI_01768 8.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EDPEAEPI_01769 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDPEAEPI_01770 2.8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDPEAEPI_01771 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EDPEAEPI_01773 2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDPEAEPI_01774 1.6e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EDPEAEPI_01775 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_01776 1.2e-287 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
EDPEAEPI_01777 9.2e-178 scrR K Transcriptional regulator
EDPEAEPI_01778 3.1e-72 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EDPEAEPI_01779 1.7e-61 yqhY S protein conserved in bacteria
EDPEAEPI_01780 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EDPEAEPI_01781 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
EDPEAEPI_01782 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EDPEAEPI_01784 2.4e-142 V 'abc transporter, ATP-binding protein
EDPEAEPI_01785 1.2e-32 blpT
EDPEAEPI_01789 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EDPEAEPI_01790 6.5e-168 corA P COG0598 Mg2 and Co2 transporters
EDPEAEPI_01791 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
EDPEAEPI_01793 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EDPEAEPI_01794 2.8e-83 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDPEAEPI_01795 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EDPEAEPI_01796 1.7e-43 XK27_05745
EDPEAEPI_01797 1.3e-223 mutY L A G-specific adenine glycosylase
EDPEAEPI_01799 3.9e-31
EDPEAEPI_01800 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EDPEAEPI_01801 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EDPEAEPI_01802 6.1e-94 cvpA S toxin biosynthetic process
EDPEAEPI_01803 2.7e-14 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EDPEAEPI_01804 2e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDPEAEPI_01805 1.4e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDPEAEPI_01806 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EDPEAEPI_01807 4.8e-46 azlD S branched-chain amino acid
EDPEAEPI_01808 3e-114 azlC E AzlC protein
EDPEAEPI_01809 8.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EDPEAEPI_01810 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EDPEAEPI_01811 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EDPEAEPI_01812 4.3e-33 ykzG S Belongs to the UPF0356 family
EDPEAEPI_01813 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDPEAEPI_01814 8e-114 pscB M CHAP domain protein
EDPEAEPI_01815 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
EDPEAEPI_01816 2.5e-62 glnR K Transcriptional regulator
EDPEAEPI_01817 5.6e-86 S Fusaric acid resistance protein-like
EDPEAEPI_01818 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EDPEAEPI_01819 5.8e-97
EDPEAEPI_01820 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EDPEAEPI_01821 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EDPEAEPI_01822 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EDPEAEPI_01823 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EDPEAEPI_01824 5.3e-142 purR 2.4.2.7 F operon repressor
EDPEAEPI_01825 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
EDPEAEPI_01826 2.5e-170 rmuC S RmuC domain protein
EDPEAEPI_01827 2.9e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
EDPEAEPI_01828 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EDPEAEPI_01829 2.4e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EDPEAEPI_01831 1.9e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EDPEAEPI_01832 5.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EDPEAEPI_01833 5.2e-142 tatD L Hydrolase, tatd
EDPEAEPI_01834 7.2e-74 yccU S CoA-binding protein
EDPEAEPI_01835 2.4e-50 trxA O Belongs to the thioredoxin family
EDPEAEPI_01836 2.3e-142 S Macro domain protein
EDPEAEPI_01837 5.2e-61 L thioesterase
EDPEAEPI_01838 5.5e-53 bta 1.8.1.8 CO cell redox homeostasis
EDPEAEPI_01841 1.8e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EDPEAEPI_01842 3.4e-14 rpmH J Ribosomal protein L34
EDPEAEPI_01843 3.4e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EDPEAEPI_01844 4.3e-101 K Transcriptional regulator
EDPEAEPI_01845 4.6e-175 jag S RNA-binding protein
EDPEAEPI_01846 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDPEAEPI_01847 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EDPEAEPI_01848 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
EDPEAEPI_01849 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EDPEAEPI_01850 1.8e-128 fasA KT Response regulator of the LytR AlgR family
EDPEAEPI_01851 8e-225 fasC 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01852 1.9e-207 hpk9 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01853 8.8e-151 hpk9 2.7.13.3 T protein histidine kinase activity
EDPEAEPI_01854 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EDPEAEPI_01855 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EDPEAEPI_01856 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EDPEAEPI_01857 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EDPEAEPI_01858 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EDPEAEPI_01859 1.2e-50 S Protein of unknown function (DUF3397)
EDPEAEPI_01860 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EDPEAEPI_01861 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
EDPEAEPI_01862 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EDPEAEPI_01863 6.4e-77 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
EDPEAEPI_01864 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EDPEAEPI_01865 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
EDPEAEPI_01866 9.3e-231 XK27_09615 C reductase
EDPEAEPI_01867 2.1e-140 fnt P Formate nitrite transporter
EDPEAEPI_01868 1.6e-94 XK27_08585 S Psort location CytoplasmicMembrane, score
EDPEAEPI_01869 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EDPEAEPI_01870 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EDPEAEPI_01871 3.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EDPEAEPI_01872 1e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EDPEAEPI_01873 1.1e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EDPEAEPI_01874 7.6e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EDPEAEPI_01875 7.3e-138 S HAD hydrolase, family IA, variant
EDPEAEPI_01876 1.8e-153 rrmA 2.1.1.187 Q methyltransferase
EDPEAEPI_01880 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EDPEAEPI_01881 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDPEAEPI_01882 1.9e-116 S CAAX protease self-immunity
EDPEAEPI_01883 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDPEAEPI_01885 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EDPEAEPI_01886 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
EDPEAEPI_01887 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EDPEAEPI_01888 1.1e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EDPEAEPI_01889 1.6e-101 S CAAX amino terminal protease family protein
EDPEAEPI_01891 1.4e-108 V CAAX protease self-immunity
EDPEAEPI_01892 8.8e-27 lanR K sequence-specific DNA binding
EDPEAEPI_01893 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDPEAEPI_01894 1.1e-175 ytxK 2.1.1.72 L DNA methylase
EDPEAEPI_01895 2e-12 comGF U Putative Competence protein ComGF
EDPEAEPI_01896 4.5e-71 comGF U Competence protein ComGF
EDPEAEPI_01897 3.1e-15 NU Type II secretory pathway pseudopilin
EDPEAEPI_01898 8.4e-70 cglD NU Competence protein
EDPEAEPI_01899 7.5e-37 comGC U Required for transformation and DNA binding
EDPEAEPI_01900 8.8e-145 cglB U protein transport across the cell outer membrane
EDPEAEPI_01901 7.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EDPEAEPI_01902 1e-68 S cog cog4699
EDPEAEPI_01903 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDPEAEPI_01904 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDPEAEPI_01905 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDPEAEPI_01906 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EDPEAEPI_01907 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EDPEAEPI_01908 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
EDPEAEPI_01909 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EDPEAEPI_01910 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDPEAEPI_01911 6e-302 yloV S kinase related to dihydroxyacetone kinase
EDPEAEPI_01912 1.4e-57 asp S cog cog1302
EDPEAEPI_01913 1.2e-225 norN V Mate efflux family protein
EDPEAEPI_01914 5.1e-276 thrC 4.2.3.1 E Threonine synthase
EDPEAEPI_01917 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDPEAEPI_01918 0.0 pepO 3.4.24.71 O Peptidase family M13
EDPEAEPI_01919 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDPEAEPI_01920 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_01921 4.3e-124 treR K trehalose operon
EDPEAEPI_01922 4.3e-95 ywlG S Belongs to the UPF0340 family
EDPEAEPI_01925 1.1e-48
EDPEAEPI_01926 0.0 S Protein of unknown function DUF262
EDPEAEPI_01927 2.9e-102
EDPEAEPI_01929 1e-77 S EcsC protein family
EDPEAEPI_01931 1.4e-47
EDPEAEPI_01932 4e-140
EDPEAEPI_01933 4.9e-285 dcm 2.1.1.37, 2.1.1.72 H Adenine-specific methyltransferase EcoRI
EDPEAEPI_01934 1.7e-85 K Peptidase S24-like protein
EDPEAEPI_01935 9.1e-92 E IrrE N-terminal-like domain
EDPEAEPI_01936 1.4e-40 S Domain of unknown function (DUF4263)
EDPEAEPI_01937 4.3e-37 K Helix-turn-helix XRE-family like proteins
EDPEAEPI_01938 5e-42
EDPEAEPI_01939 8.6e-73
EDPEAEPI_01940 8.9e-277 ydcQ D Ftsk spoiiie family protein
EDPEAEPI_01941 3.4e-225 K Replication initiation factor
EDPEAEPI_01942 5.7e-33
EDPEAEPI_01943 9.6e-87
EDPEAEPI_01944 2.6e-159 S Conjugative transposon protein TcpC
EDPEAEPI_01945 3.2e-33
EDPEAEPI_01946 1.5e-68 S TcpE family
EDPEAEPI_01947 0.0 yddE S AAA-like domain
EDPEAEPI_01948 3.9e-265
EDPEAEPI_01949 4.4e-30
EDPEAEPI_01950 1.3e-170 isp2 S pathogenesis
EDPEAEPI_01951 4e-16
EDPEAEPI_01952 3.8e-198 L DNA integration
EDPEAEPI_01953 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EDPEAEPI_01955 7.4e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
EDPEAEPI_01956 4.4e-62 rplQ J ribosomal protein l17
EDPEAEPI_01957 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDPEAEPI_01958 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EDPEAEPI_01959 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EDPEAEPI_01960 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EDPEAEPI_01961 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EDPEAEPI_01962 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EDPEAEPI_01963 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EDPEAEPI_01964 5.7e-58 rplO J binds to the 23S rRNA
EDPEAEPI_01965 1.9e-23 rpmD J ribosomal protein l30
EDPEAEPI_01966 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EDPEAEPI_01967 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EDPEAEPI_01968 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EDPEAEPI_01969 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EDPEAEPI_01970 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EDPEAEPI_01971 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EDPEAEPI_01972 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EDPEAEPI_01973 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EDPEAEPI_01974 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EDPEAEPI_01975 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EDPEAEPI_01976 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EDPEAEPI_01977 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EDPEAEPI_01978 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EDPEAEPI_01979 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EDPEAEPI_01980 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EDPEAEPI_01981 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EDPEAEPI_01982 1.1e-102 rplD J Forms part of the polypeptide exit tunnel
EDPEAEPI_01983 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EDPEAEPI_01984 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EDPEAEPI_01985 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EDPEAEPI_01986 0.0 XK27_09800 I Acyltransferase
EDPEAEPI_01987 9.7e-36 XK27_09805 S MORN repeat protein
EDPEAEPI_01988 4.9e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EDPEAEPI_01989 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EDPEAEPI_01990 4.1e-92 adk 2.7.4.3 F topology modulation protein
EDPEAEPI_01992 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EDPEAEPI_01993 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EDPEAEPI_01994 6.3e-44 yrzL S Belongs to the UPF0297 family
EDPEAEPI_01995 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EDPEAEPI_01996 3.2e-44 yrzB S Belongs to the UPF0473 family
EDPEAEPI_01997 1.4e-295 ccs S the current gene model (or a revised gene model) may contain a frame shift
EDPEAEPI_01998 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EDPEAEPI_01999 7.5e-14
EDPEAEPI_02000 4.1e-89 XK27_10930 K acetyltransferase
EDPEAEPI_02001 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDPEAEPI_02002 4e-122 yaaA S Belongs to the UPF0246 family
EDPEAEPI_02003 3.2e-167 XK27_01785 S cog cog1284
EDPEAEPI_02004 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EDPEAEPI_02006 5e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
EDPEAEPI_02007 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_02008 1.7e-129 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EDPEAEPI_02009 5.6e-219 metE 2.1.1.14 E Methionine synthase
EDPEAEPI_02010 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EDPEAEPI_02011 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EDPEAEPI_02012 1.2e-42 4.2.1.53 S MCRA family
EDPEAEPI_02013 6.7e-49 S membrane protein of uknown function UCP014873
EDPEAEPI_02015 4.8e-221 sip L Phage integrase, N-terminal SAM-like domain
EDPEAEPI_02016 7.3e-61 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
EDPEAEPI_02017 1.3e-92 L Transposase
EDPEAEPI_02018 9.5e-47 fruR K transcriptional
EDPEAEPI_02019 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EDPEAEPI_02020 9.9e-162 T Diguanylate cyclase
EDPEAEPI_02021 3.4e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EDPEAEPI_02022 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
EDPEAEPI_02023 0.0
EDPEAEPI_02024 1.5e-26 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDPEAEPI_02029 2.4e-115 nudL L hydrolase
EDPEAEPI_02030 7e-53 K transcriptional regulator, PadR family
EDPEAEPI_02031 3.1e-67 XK27_06920 S Protein of unknown function (DUF1700)
EDPEAEPI_02032 1.3e-106 S Putative adhesin
EDPEAEPI_02033 1.5e-160 XK27_06930 V domain protein
EDPEAEPI_02034 9.9e-97 XK27_06935 K transcriptional regulator
EDPEAEPI_02035 2e-53 ypaA M Membrane
EDPEAEPI_02036 1.9e-10
EDPEAEPI_02037 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EDPEAEPI_02038 1.8e-47 veg S Biofilm formation stimulator VEG
EDPEAEPI_02039 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EDPEAEPI_02040 2.2e-73 rplI J binds to the 23S rRNA
EDPEAEPI_02041 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EDPEAEPI_02042 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EDPEAEPI_02043 2.1e-98 yvbG U UPF0056 membrane protein
EDPEAEPI_02044 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EDPEAEPI_02045 2.4e-311 S Bacterial membrane protein, YfhO
EDPEAEPI_02046 7.6e-65 isaA GH23 M Immunodominant staphylococcal antigen A
EDPEAEPI_02047 2.7e-71 lytE M LysM domain protein
EDPEAEPI_02048 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDPEAEPI_02049 6.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDPEAEPI_02050 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDPEAEPI_02051 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EDPEAEPI_02052 5.7e-131 S sequence-specific DNA binding
EDPEAEPI_02053 7.5e-236 ymfH S Peptidase M16
EDPEAEPI_02054 1.3e-227 ymfF S Peptidase M16
EDPEAEPI_02055 3.7e-58 yaaA S S4 domain protein YaaA
EDPEAEPI_02056 5e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EDPEAEPI_02057 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EDPEAEPI_02058 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EDPEAEPI_02059 7.1e-153 yvjA S membrane
EDPEAEPI_02060 4.3e-305 ybiT S abc transporter atp-binding protein
EDPEAEPI_02061 0.0 XK27_10405 S Bacterial membrane protein YfhO
EDPEAEPI_02064 2.4e-119 yoaK S Protein of unknown function (DUF1275)
EDPEAEPI_02065 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EDPEAEPI_02066 1.5e-204 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EDPEAEPI_02067 2.6e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)