ORF_ID e_value Gene_name EC_number CAZy COGs Description
CLAGIPMF_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLAGIPMF_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CLAGIPMF_00003 1.1e-29 yyzM S Protein conserved in bacteria
CLAGIPMF_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CLAGIPMF_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CLAGIPMF_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLAGIPMF_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CLAGIPMF_00008 2.7e-61 divIC D Septum formation initiator
CLAGIPMF_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CLAGIPMF_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CLAGIPMF_00012 8.5e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CLAGIPMF_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLAGIPMF_00014 1.3e-137 L Transposase
CLAGIPMF_00015 1.1e-92 L Transposase
CLAGIPMF_00016 1.8e-56 L transposition
CLAGIPMF_00017 1.9e-86 L Integrase core domain protein
CLAGIPMF_00030 5.3e-11
CLAGIPMF_00036 5.5e-139 mreC M Involved in formation and maintenance of cell shape
CLAGIPMF_00037 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLAGIPMF_00038 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
CLAGIPMF_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLAGIPMF_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
CLAGIPMF_00041 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
CLAGIPMF_00042 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CLAGIPMF_00043 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLAGIPMF_00044 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CLAGIPMF_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLAGIPMF_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLAGIPMF_00047 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CLAGIPMF_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLAGIPMF_00049 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CLAGIPMF_00050 6.1e-79 L transposase activity
CLAGIPMF_00051 1.3e-49 L transposition
CLAGIPMF_00052 4.2e-32 L Integrase core domain protein
CLAGIPMF_00053 4.1e-158 L COG2801 Transposase and inactivated derivatives
CLAGIPMF_00054 8.1e-45 L Transposase
CLAGIPMF_00055 2.3e-161 S CHAP domain
CLAGIPMF_00056 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
CLAGIPMF_00057 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLAGIPMF_00058 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLAGIPMF_00059 9.2e-141 1.1.1.169 H Ketopantoate reductase
CLAGIPMF_00060 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLAGIPMF_00061 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CLAGIPMF_00062 1.2e-09 L Transposase
CLAGIPMF_00063 1.8e-212 ugd 1.1.1.22 M UDP binding domain
CLAGIPMF_00064 1.3e-205 nodC 2.4.1.212 GT2 M Chitin synthase
CLAGIPMF_00065 1.3e-87 FNV0100 F Belongs to the Nudix hydrolase family
CLAGIPMF_00066 3.5e-28 3.4.13.21 I Protein conserved in bacteria
CLAGIPMF_00069 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
CLAGIPMF_00071 8.2e-70 argR K Regulates arginine biosynthesis genes
CLAGIPMF_00072 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CLAGIPMF_00073 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLAGIPMF_00074 7e-34 S Protein of unknown function (DUF3021)
CLAGIPMF_00075 1.2e-61 KT phosphorelay signal transduction system
CLAGIPMF_00077 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLAGIPMF_00079 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CLAGIPMF_00080 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CLAGIPMF_00081 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
CLAGIPMF_00082 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLAGIPMF_00083 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CLAGIPMF_00089 2.6e-10
CLAGIPMF_00092 1.9e-07
CLAGIPMF_00097 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLAGIPMF_00098 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CLAGIPMF_00099 5.5e-36 XK27_02060 S Transglycosylase associated protein
CLAGIPMF_00100 2.6e-55 badR K DNA-binding transcription factor activity
CLAGIPMF_00101 4.6e-97 S reductase
CLAGIPMF_00102 2.6e-88 L Integrase core domain protein
CLAGIPMF_00103 3.2e-40 L transposition
CLAGIPMF_00104 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
CLAGIPMF_00105 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CLAGIPMF_00108 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
CLAGIPMF_00109 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLAGIPMF_00110 1.1e-83 S Putative small multi-drug export protein
CLAGIPMF_00111 6.2e-76 ctsR K Belongs to the CtsR family
CLAGIPMF_00112 0.0 clpC O Belongs to the ClpA ClpB family
CLAGIPMF_00113 8.1e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_00114 8.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_00115 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_00116 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CLAGIPMF_00117 4.5e-143 S SseB protein N-terminal domain
CLAGIPMF_00118 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
CLAGIPMF_00119 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CLAGIPMF_00120 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLAGIPMF_00123 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLAGIPMF_00124 1e-84 yacP S RNA-binding protein containing a PIN domain
CLAGIPMF_00125 2.2e-154 degV S DegV family
CLAGIPMF_00126 2.3e-31 K helix-turn-helix
CLAGIPMF_00127 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLAGIPMF_00128 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLAGIPMF_00129 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CLAGIPMF_00130 1.5e-35 K sequence-specific DNA binding
CLAGIPMF_00132 0.0 S Lantibiotic dehydratase, C terminus
CLAGIPMF_00133 2.4e-231 spaC2 V Lanthionine synthetase C family protein
CLAGIPMF_00134 4.3e-183 EGP Major facilitator Superfamily
CLAGIPMF_00135 5.9e-24 3.6.4.12
CLAGIPMF_00136 5.9e-91 3.6.4.12 K Divergent AAA domain protein
CLAGIPMF_00137 7.4e-225 int L Belongs to the 'phage' integrase family
CLAGIPMF_00138 1.8e-38 S Helix-turn-helix domain
CLAGIPMF_00139 4.9e-173
CLAGIPMF_00141 3.4e-75 isp2 S pathogenesis
CLAGIPMF_00142 5.7e-91 tnp L Transposase
CLAGIPMF_00143 3.3e-225 capA M Bacterial capsule synthesis protein
CLAGIPMF_00144 3.6e-39 gcvR T UPF0237 protein
CLAGIPMF_00145 1.9e-242 XK27_08635 S UPF0210 protein
CLAGIPMF_00146 2.2e-38 ais G alpha-ribazole phosphatase activity
CLAGIPMF_00147 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CLAGIPMF_00148 1.3e-102 acmA 3.2.1.17 NU amidase activity
CLAGIPMF_00149 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CLAGIPMF_00150 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLAGIPMF_00151 9.8e-298 dnaK O Heat shock 70 kDa protein
CLAGIPMF_00152 9.4e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CLAGIPMF_00153 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CLAGIPMF_00154 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CLAGIPMF_00155 1.7e-60 hmpT S membrane
CLAGIPMF_00168 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CLAGIPMF_00169 2.5e-169 L Transposase
CLAGIPMF_00170 9.9e-19 S Domain of unknown function (DUF4649)
CLAGIPMF_00171 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CLAGIPMF_00172 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CLAGIPMF_00173 6.5e-87
CLAGIPMF_00174 1.6e-77 sigH K DNA-templated transcription, initiation
CLAGIPMF_00175 3.5e-149 ykuT M mechanosensitive ion channel
CLAGIPMF_00176 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CLAGIPMF_00177 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CLAGIPMF_00178 4.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CLAGIPMF_00179 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
CLAGIPMF_00180 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CLAGIPMF_00181 2e-177 prmA J Ribosomal protein L11 methyltransferase
CLAGIPMF_00182 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CLAGIPMF_00183 1.4e-42 F nucleotide catabolic process
CLAGIPMF_00184 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CLAGIPMF_00185 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CLAGIPMF_00186 3.8e-81 nrdI F Belongs to the NrdI family
CLAGIPMF_00187 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLAGIPMF_00188 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CLAGIPMF_00189 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CLAGIPMF_00190 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CLAGIPMF_00191 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CLAGIPMF_00192 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CLAGIPMF_00193 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLAGIPMF_00194 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CLAGIPMF_00195 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CLAGIPMF_00196 6.5e-202 yhjX P Major Facilitator
CLAGIPMF_00197 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLAGIPMF_00198 5e-94 V VanZ like family
CLAGIPMF_00199 1e-123 glnQ E abc transporter atp-binding protein
CLAGIPMF_00200 5.8e-275 glnP P ABC transporter
CLAGIPMF_00201 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CLAGIPMF_00202 1.5e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CLAGIPMF_00203 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
CLAGIPMF_00204 1.1e-143 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CLAGIPMF_00205 1.4e-234 sufD O assembly protein SufD
CLAGIPMF_00206 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLAGIPMF_00207 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
CLAGIPMF_00208 2.2e-273 sufB O assembly protein SufB
CLAGIPMF_00209 7e-10 oppA E ABC transporter substrate-binding protein
CLAGIPMF_00210 2e-138 oppA E ABC transporter substrate-binding protein
CLAGIPMF_00211 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAGIPMF_00212 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAGIPMF_00213 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAGIPMF_00214 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLAGIPMF_00215 3e-27 oppD P Belongs to the ABC transporter superfamily
CLAGIPMF_00216 2.5e-32 oppD P Belongs to the ABC transporter superfamily
CLAGIPMF_00217 1.2e-62 oppD P Belongs to the ABC transporter superfamily
CLAGIPMF_00218 3.1e-43 oppD P Belongs to the ABC transporter superfamily
CLAGIPMF_00219 7.5e-62 oppF P Belongs to the ABC transporter superfamily
CLAGIPMF_00220 3.4e-62 oppF P Belongs to the ABC transporter superfamily
CLAGIPMF_00221 6.4e-23
CLAGIPMF_00222 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLAGIPMF_00223 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLAGIPMF_00224 9.4e-223 EGP Major facilitator Superfamily
CLAGIPMF_00225 3.1e-72 adcR K transcriptional
CLAGIPMF_00226 2.2e-136 adcC P ABC transporter, ATP-binding protein
CLAGIPMF_00227 1.6e-127 adcB P ABC transporter (Permease
CLAGIPMF_00228 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CLAGIPMF_00229 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
CLAGIPMF_00230 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
CLAGIPMF_00231 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CLAGIPMF_00232 1.2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CLAGIPMF_00233 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
CLAGIPMF_00234 1.9e-127 yeeN K transcriptional regulatory protein
CLAGIPMF_00235 9.8e-50 yajC U protein transport
CLAGIPMF_00236 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLAGIPMF_00237 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
CLAGIPMF_00238 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CLAGIPMF_00239 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CLAGIPMF_00240 0.0 WQ51_06230 S ABC transporter substrate binding protein
CLAGIPMF_00241 5.2e-142 cmpC S abc transporter atp-binding protein
CLAGIPMF_00242 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLAGIPMF_00243 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CLAGIPMF_00244 4.4e-37 L Transposase
CLAGIPMF_00245 2.6e-19 L transposase activity
CLAGIPMF_00246 1.9e-50 L transposition
CLAGIPMF_00247 1.4e-33 L Integrase core domain protein
CLAGIPMF_00249 1.7e-54 S TM2 domain
CLAGIPMF_00250 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CLAGIPMF_00251 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CLAGIPMF_00252 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CLAGIPMF_00253 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
CLAGIPMF_00254 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CLAGIPMF_00255 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CLAGIPMF_00256 6e-55 cof Q phosphatase activity
CLAGIPMF_00257 6.2e-35 cof Q phosphatase activity
CLAGIPMF_00258 8.2e-137 glcR K transcriptional regulator (DeoR family)
CLAGIPMF_00259 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CLAGIPMF_00260 3.8e-40 K transcriptional
CLAGIPMF_00262 2.6e-76 S thiolester hydrolase activity
CLAGIPMF_00263 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
CLAGIPMF_00264 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLAGIPMF_00265 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CLAGIPMF_00266 1.9e-77 yhaI L Membrane
CLAGIPMF_00267 5.1e-259 pepC 3.4.22.40 E aminopeptidase
CLAGIPMF_00268 1.6e-249 L Transposase
CLAGIPMF_00269 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CLAGIPMF_00270 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CLAGIPMF_00271 3.1e-95 ypsA S Belongs to the UPF0398 family
CLAGIPMF_00272 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CLAGIPMF_00273 1.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CLAGIPMF_00274 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CLAGIPMF_00275 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CLAGIPMF_00276 8.2e-22
CLAGIPMF_00277 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CLAGIPMF_00278 7.3e-80 XK27_09675 K -acetyltransferase
CLAGIPMF_00279 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLAGIPMF_00280 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLAGIPMF_00281 5.2e-59 L Integrase core domain protein
CLAGIPMF_00282 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLAGIPMF_00283 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CLAGIPMF_00284 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLAGIPMF_00285 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CLAGIPMF_00286 8.8e-98 ybhL S Belongs to the BI1 family
CLAGIPMF_00289 3.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CLAGIPMF_00290 3.7e-91 K transcriptional regulator
CLAGIPMF_00291 7.6e-36 yneF S UPF0154 protein
CLAGIPMF_00292 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CLAGIPMF_00293 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLAGIPMF_00294 3.5e-99 XK27_09740 S Phosphoesterase
CLAGIPMF_00295 7.8e-85 ykuL S CBS domain
CLAGIPMF_00296 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CLAGIPMF_00297 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLAGIPMF_00298 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLAGIPMF_00299 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CLAGIPMF_00300 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CLAGIPMF_00301 1.2e-258 trkH P Cation transport protein
CLAGIPMF_00302 1.5e-247 trkA P Potassium transporter peripheral membrane component
CLAGIPMF_00303 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CLAGIPMF_00304 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLAGIPMF_00305 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CLAGIPMF_00306 5.6e-161 K sequence-specific DNA binding
CLAGIPMF_00307 1.2e-32 V protein secretion by the type I secretion system
CLAGIPMF_00308 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CLAGIPMF_00309 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CLAGIPMF_00310 1.8e-34 V protein secretion by the type I secretion system
CLAGIPMF_00311 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CLAGIPMF_00312 1.8e-50 yhaI L Membrane
CLAGIPMF_00313 2.1e-105 S Domain of unknown function (DUF4173)
CLAGIPMF_00314 6.8e-95 ureI S AmiS/UreI family transporter
CLAGIPMF_00315 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CLAGIPMF_00316 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CLAGIPMF_00317 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CLAGIPMF_00318 6.6e-78 ureE O enzyme active site formation
CLAGIPMF_00319 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CLAGIPMF_00320 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLAGIPMF_00321 2.2e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CLAGIPMF_00322 1.1e-175 cbiM P PDGLE domain
CLAGIPMF_00323 1.1e-136 P cobalt transport protein
CLAGIPMF_00324 1.6e-131 cbiO P ABC transporter
CLAGIPMF_00325 5.3e-153 ET amino acid transport
CLAGIPMF_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLAGIPMF_00327 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
CLAGIPMF_00328 3.8e-205 EGP Transmembrane secretion effector
CLAGIPMF_00329 1.8e-153 ET amino acid transport
CLAGIPMF_00330 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
CLAGIPMF_00331 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CLAGIPMF_00332 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
CLAGIPMF_00333 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
CLAGIPMF_00334 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLAGIPMF_00335 5.2e-98 metI P ABC transporter (Permease
CLAGIPMF_00336 1.5e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLAGIPMF_00337 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CLAGIPMF_00338 8e-94 S UPF0397 protein
CLAGIPMF_00339 0.0 ykoD P abc transporter atp-binding protein
CLAGIPMF_00340 1.2e-146 cbiQ P cobalt transport
CLAGIPMF_00341 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLAGIPMF_00342 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
CLAGIPMF_00343 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
CLAGIPMF_00344 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
CLAGIPMF_00345 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CLAGIPMF_00346 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
CLAGIPMF_00347 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLAGIPMF_00348 2.8e-282 T PhoQ Sensor
CLAGIPMF_00349 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLAGIPMF_00350 5e-218 dnaB L Replication initiation and membrane attachment
CLAGIPMF_00351 4e-167 dnaI L Primosomal protein DnaI
CLAGIPMF_00352 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CLAGIPMF_00353 9e-88 yrdC 3.5.1.19 Q isochorismatase
CLAGIPMF_00354 1.3e-79 L PFAM Integrase catalytic region
CLAGIPMF_00355 1.7e-54 L transposition
CLAGIPMF_00356 5e-23 L Transposase
CLAGIPMF_00357 2.3e-32 L transposase activity
CLAGIPMF_00358 1.3e-221 L Transposase
CLAGIPMF_00360 4.3e-41 L Protein of unknown function (DUF3991)
CLAGIPMF_00361 4.6e-95 L Transposase
CLAGIPMF_00362 3.2e-89 L Transposase
CLAGIPMF_00363 5e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLAGIPMF_00364 6.5e-63 manO S protein conserved in bacteria
CLAGIPMF_00365 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
CLAGIPMF_00366 5e-108 manM G pts system
CLAGIPMF_00367 1.1e-181 manL 2.7.1.191 G pts system
CLAGIPMF_00368 4.4e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CLAGIPMF_00369 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CLAGIPMF_00370 2.1e-247 pbuO S permease
CLAGIPMF_00371 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CLAGIPMF_00372 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
CLAGIPMF_00373 2.5e-220 brpA K Transcriptional
CLAGIPMF_00374 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
CLAGIPMF_00375 3.1e-212 nusA K Participates in both transcription termination and antitermination
CLAGIPMF_00376 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CLAGIPMF_00377 1.4e-41 ylxQ J ribosomal protein
CLAGIPMF_00378 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLAGIPMF_00379 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLAGIPMF_00380 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
CLAGIPMF_00381 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
CLAGIPMF_00382 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CLAGIPMF_00383 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CLAGIPMF_00384 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLAGIPMF_00385 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CLAGIPMF_00386 3.3e-77 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CLAGIPMF_00387 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
CLAGIPMF_00388 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CLAGIPMF_00390 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLAGIPMF_00391 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CLAGIPMF_00392 1.2e-74 ylbF S Belongs to the UPF0342 family
CLAGIPMF_00393 7.1e-46 ylbG S UPF0298 protein
CLAGIPMF_00394 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CLAGIPMF_00395 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
CLAGIPMF_00396 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
CLAGIPMF_00397 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CLAGIPMF_00398 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CLAGIPMF_00399 6.8e-69 acuB S IMP dehydrogenase activity
CLAGIPMF_00400 8.9e-41 acuB S IMP dehydrogenase activity
CLAGIPMF_00401 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CLAGIPMF_00402 1.1e-110 yvyE 3.4.13.9 S YigZ family
CLAGIPMF_00403 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CLAGIPMF_00404 1.7e-122 comFC S Competence protein
CLAGIPMF_00405 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLAGIPMF_00413 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
CLAGIPMF_00414 6.4e-108 S Domain of unknown function (DUF1803)
CLAGIPMF_00415 7.8e-102 ygaC J Belongs to the UPF0374 family
CLAGIPMF_00416 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
CLAGIPMF_00417 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLAGIPMF_00418 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
CLAGIPMF_00419 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
CLAGIPMF_00420 1.9e-115 S Haloacid dehalogenase-like hydrolase
CLAGIPMF_00421 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CLAGIPMF_00422 4e-72 marR K Transcriptional regulator, MarR family
CLAGIPMF_00423 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLAGIPMF_00424 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLAGIPMF_00425 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CLAGIPMF_00426 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CLAGIPMF_00427 1.6e-126 IQ reductase
CLAGIPMF_00428 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CLAGIPMF_00429 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CLAGIPMF_00430 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLAGIPMF_00431 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CLAGIPMF_00432 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLAGIPMF_00433 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CLAGIPMF_00434 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CLAGIPMF_00435 1.1e-65 tnp L Transposase
CLAGIPMF_00436 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
CLAGIPMF_00437 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
CLAGIPMF_00438 4.7e-27 L Transposase and inactivated derivatives, TnpA family
CLAGIPMF_00439 3.4e-126 tnp L Transposase
CLAGIPMF_00441 8e-277 S Protein of unknown function (DUF3114)
CLAGIPMF_00442 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
CLAGIPMF_00443 7.7e-198 V (ABC) transporter
CLAGIPMF_00444 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
CLAGIPMF_00445 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
CLAGIPMF_00446 1.1e-113 K sequence-specific DNA binding
CLAGIPMF_00447 8.4e-155 L COG2801 Transposase and inactivated derivatives
CLAGIPMF_00448 6.6e-38 L transposase activity
CLAGIPMF_00449 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
CLAGIPMF_00450 1.8e-84 L Transposase
CLAGIPMF_00451 5.5e-122 fruR K transcriptional
CLAGIPMF_00452 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CLAGIPMF_00453 0.0 fruA 2.7.1.202 G phosphotransferase system
CLAGIPMF_00454 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLAGIPMF_00455 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CLAGIPMF_00457 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CLAGIPMF_00458 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLAGIPMF_00459 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CLAGIPMF_00460 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CLAGIPMF_00461 6.4e-29 2.3.1.128 K acetyltransferase
CLAGIPMF_00462 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CLAGIPMF_00463 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CLAGIPMF_00464 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLAGIPMF_00465 2.6e-64 WQ51_03320 S cog cog4835
CLAGIPMF_00466 9.8e-91 XK27_08360 S EDD domain protein, DegV family
CLAGIPMF_00467 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CLAGIPMF_00468 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CLAGIPMF_00469 0.0 yfmR S abc transporter atp-binding protein
CLAGIPMF_00470 7.2e-25 U response to pH
CLAGIPMF_00471 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CLAGIPMF_00472 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CLAGIPMF_00473 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CLAGIPMF_00474 5.8e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CLAGIPMF_00475 1.9e-77 K DNA-binding transcription factor activity
CLAGIPMF_00476 0.0 lmrA1 V abc transporter atp-binding protein
CLAGIPMF_00477 0.0 lmrA2 V abc transporter atp-binding protein
CLAGIPMF_00478 5.4e-45 K Acetyltransferase (GNAT) family
CLAGIPMF_00479 3.2e-78 sptS 2.7.13.3 T Histidine kinase
CLAGIPMF_00480 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CLAGIPMF_00481 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CLAGIPMF_00482 1.7e-159 cvfB S Protein conserved in bacteria
CLAGIPMF_00483 7.4e-35 yozE S Belongs to the UPF0346 family
CLAGIPMF_00484 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
CLAGIPMF_00485 2.3e-61 rlpA M LysM domain protein
CLAGIPMF_00486 8e-191 phoH T phosphate starvation-inducible protein PhoH
CLAGIPMF_00490 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLAGIPMF_00491 1.8e-164 K transcriptional regulator (lysR family)
CLAGIPMF_00492 1.4e-186 coiA 3.6.4.12 S Competence protein
CLAGIPMF_00493 0.0 pepF E oligoendopeptidase F
CLAGIPMF_00494 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
CLAGIPMF_00495 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CLAGIPMF_00496 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLAGIPMF_00497 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CLAGIPMF_00498 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CLAGIPMF_00499 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
CLAGIPMF_00500 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CLAGIPMF_00501 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CLAGIPMF_00502 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLAGIPMF_00503 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLAGIPMF_00504 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CLAGIPMF_00505 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CLAGIPMF_00506 2.2e-130 yxkH G deacetylase
CLAGIPMF_00507 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CLAGIPMF_00508 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CLAGIPMF_00509 1.4e-151 rarD S Transporter
CLAGIPMF_00510 2.9e-15 T peptidase
CLAGIPMF_00511 5.7e-13 coiA 3.6.4.12 S Competence protein
CLAGIPMF_00512 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLAGIPMF_00513 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLAGIPMF_00514 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CLAGIPMF_00515 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLAGIPMF_00516 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
CLAGIPMF_00517 3.3e-78 atpF C ATP synthase F(0) sector subunit b
CLAGIPMF_00518 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLAGIPMF_00519 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLAGIPMF_00520 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLAGIPMF_00521 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLAGIPMF_00522 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CLAGIPMF_00523 2.8e-230 ftsW D Belongs to the SEDS family
CLAGIPMF_00524 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLAGIPMF_00525 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLAGIPMF_00526 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLAGIPMF_00527 6.4e-162 holB 2.7.7.7 L dna polymerase iii
CLAGIPMF_00528 1.2e-135 yaaT S stage 0 sporulation protein
CLAGIPMF_00529 9.5e-55 yabA L Involved in initiation control of chromosome replication
CLAGIPMF_00530 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLAGIPMF_00531 2.2e-232 amt P Ammonium Transporter
CLAGIPMF_00532 1.1e-53 glnB K Belongs to the P(II) protein family
CLAGIPMF_00533 4.9e-106 mur1 NU mannosyl-glycoprotein
CLAGIPMF_00534 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CLAGIPMF_00535 4.4e-114 nptA P COG1283 Na phosphate symporter
CLAGIPMF_00536 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLAGIPMF_00537 7.4e-55
CLAGIPMF_00538 4.4e-26
CLAGIPMF_00539 1.2e-61
CLAGIPMF_00540 1.7e-32 S membrane
CLAGIPMF_00541 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CLAGIPMF_00542 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CLAGIPMF_00543 4.5e-39 ynzC S UPF0291 protein
CLAGIPMF_00544 1.8e-254 cycA E permease
CLAGIPMF_00545 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
CLAGIPMF_00546 4.8e-24 pts33BCA G pts system
CLAGIPMF_00547 1.3e-70 pts33BCA G pts system
CLAGIPMF_00548 6.1e-118 pts33BCA G pts system
CLAGIPMF_00549 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
CLAGIPMF_00550 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLAGIPMF_00555 1.4e-167 fhuR K transcriptional regulator (lysR family)
CLAGIPMF_00556 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLAGIPMF_00557 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CLAGIPMF_00558 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLAGIPMF_00559 3.7e-227 pyrP F uracil Permease
CLAGIPMF_00560 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CLAGIPMF_00561 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CLAGIPMF_00562 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CLAGIPMF_00563 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
CLAGIPMF_00564 1.7e-29 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLAGIPMF_00565 3.6e-35 V efflux transmembrane transporter activity
CLAGIPMF_00566 3.1e-31 V efflux transmembrane transporter activity
CLAGIPMF_00567 8.2e-28 ytrF V efflux transmembrane transporter activity
CLAGIPMF_00568 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLAGIPMF_00569 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CLAGIPMF_00570 1.1e-250 L Transposase
CLAGIPMF_00571 0.0 lptA M Putative Ig domain
CLAGIPMF_00572 9.1e-110 L Transposase
CLAGIPMF_00573 1.2e-109 L Transposase
CLAGIPMF_00574 1.6e-18 L Integrase core domain
CLAGIPMF_00575 4.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
CLAGIPMF_00576 5e-161 hrtB V MacB-like periplasmic core domain
CLAGIPMF_00580 2.2e-27 J glyoxalase III activity
CLAGIPMF_00581 4.6e-21 L Transposase
CLAGIPMF_00582 1.2e-15
CLAGIPMF_00584 0.0 mdlB V abc transporter atp-binding protein
CLAGIPMF_00585 0.0 lmrA V abc transporter atp-binding protein
CLAGIPMF_00586 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLAGIPMF_00587 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CLAGIPMF_00588 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CLAGIPMF_00589 2.5e-132 rr02 KT response regulator
CLAGIPMF_00590 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CLAGIPMF_00591 2.8e-168 V ABC transporter
CLAGIPMF_00592 5.4e-122 sagI S ABC-2 type transporter
CLAGIPMF_00593 6.9e-197 yceA S Belongs to the UPF0176 family
CLAGIPMF_00594 8e-28 XK27_00085 K Transcriptional
CLAGIPMF_00595 1.9e-22
CLAGIPMF_00596 5.3e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
CLAGIPMF_00597 1.3e-112 S VIT family
CLAGIPMF_00598 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CLAGIPMF_00599 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CLAGIPMF_00600 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
CLAGIPMF_00601 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CLAGIPMF_00602 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLAGIPMF_00603 8.8e-104 GBS0088 J protein conserved in bacteria
CLAGIPMF_00604 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CLAGIPMF_00605 1.6e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CLAGIPMF_00606 2.3e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
CLAGIPMF_00607 2.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CLAGIPMF_00608 7.3e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLAGIPMF_00609 4.5e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CLAGIPMF_00610 6.4e-17
CLAGIPMF_00611 2.9e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLAGIPMF_00613 3.5e-07 U protein secretion
CLAGIPMF_00614 2.7e-50 U protein secretion
CLAGIPMF_00616 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CLAGIPMF_00617 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CLAGIPMF_00618 4.9e-21 XK27_13030
CLAGIPMF_00619 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLAGIPMF_00620 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CLAGIPMF_00621 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CLAGIPMF_00622 2.6e-163 S Protein of unknown function (DUF3114)
CLAGIPMF_00623 1.2e-22 S Protein of unknown function (DUF3114)
CLAGIPMF_00624 1.5e-118 yqfA K protein, Hemolysin III
CLAGIPMF_00625 1e-25 K hmm pf08876
CLAGIPMF_00626 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CLAGIPMF_00627 1.7e-218 mvaS 2.3.3.10 I synthase
CLAGIPMF_00628 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLAGIPMF_00629 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLAGIPMF_00630 9.7e-22
CLAGIPMF_00631 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLAGIPMF_00632 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CLAGIPMF_00633 1.5e-250 mmuP E amino acid
CLAGIPMF_00634 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CLAGIPMF_00635 1.4e-29 S Domain of unknown function (DUF1912)
CLAGIPMF_00636 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
CLAGIPMF_00637 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CLAGIPMF_00638 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLAGIPMF_00639 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLAGIPMF_00640 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
CLAGIPMF_00641 4.8e-16 S Protein of unknown function (DUF2969)
CLAGIPMF_00644 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
CLAGIPMF_00647 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
CLAGIPMF_00648 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
CLAGIPMF_00649 3.7e-70 M Pfam SNARE associated Golgi protein
CLAGIPMF_00650 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
CLAGIPMF_00651 1.6e-08 S oxidoreductase
CLAGIPMF_00652 9.3e-59 S oxidoreductase
CLAGIPMF_00653 9.7e-66 S oxidoreductase
CLAGIPMF_00654 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
CLAGIPMF_00655 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CLAGIPMF_00656 0.0 clpE O Belongs to the ClpA ClpB family
CLAGIPMF_00657 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLAGIPMF_00658 1.3e-34 ykuJ S protein conserved in bacteria
CLAGIPMF_00659 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CLAGIPMF_00660 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_00661 1.1e-78 feoA P FeoA domain protein
CLAGIPMF_00662 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CLAGIPMF_00663 1.5e-07
CLAGIPMF_00664 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CLAGIPMF_00665 2.2e-45 K sequence-specific DNA binding
CLAGIPMF_00666 1.5e-35 yugF I carboxylic ester hydrolase activity
CLAGIPMF_00667 7.5e-23 I Alpha/beta hydrolase family
CLAGIPMF_00668 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLAGIPMF_00669 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLAGIPMF_00670 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CLAGIPMF_00671 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLAGIPMF_00672 5.8e-64 licT K transcriptional antiterminator
CLAGIPMF_00673 6.8e-53 licT K transcriptional antiterminator
CLAGIPMF_00674 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLAGIPMF_00675 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CLAGIPMF_00676 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLAGIPMF_00677 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CLAGIPMF_00678 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLAGIPMF_00679 2.5e-220 mdtG EGP Major facilitator Superfamily
CLAGIPMF_00680 2e-33 secG U Preprotein translocase subunit SecG
CLAGIPMF_00681 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CLAGIPMF_00682 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CLAGIPMF_00683 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLAGIPMF_00684 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CLAGIPMF_00685 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CLAGIPMF_00686 4.4e-183 ccpA K Catabolite control protein A
CLAGIPMF_00687 2.8e-28 yyaQ S YjbR
CLAGIPMF_00688 6.6e-101 yyaQ V Protein conserved in bacteria
CLAGIPMF_00689 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CLAGIPMF_00690 1e-78 yueI S Protein of unknown function (DUF1694)
CLAGIPMF_00691 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CLAGIPMF_00692 2e-25 WQ51_00785
CLAGIPMF_00693 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CLAGIPMF_00694 2e-219 ywbD 2.1.1.191 J Methyltransferase
CLAGIPMF_00695 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CLAGIPMF_00696 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLAGIPMF_00697 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLAGIPMF_00698 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLAGIPMF_00699 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CLAGIPMF_00700 3.2e-53 yheA S Belongs to the UPF0342 family
CLAGIPMF_00701 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CLAGIPMF_00702 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CLAGIPMF_00703 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLAGIPMF_00704 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
CLAGIPMF_00705 6.4e-252 msrR K Transcriptional regulator
CLAGIPMF_00706 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
CLAGIPMF_00707 2.4e-203 I acyl-CoA dehydrogenase
CLAGIPMF_00708 4.5e-97 mip S hydroperoxide reductase activity
CLAGIPMF_00709 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLAGIPMF_00710 8.9e-20
CLAGIPMF_00711 2e-36
CLAGIPMF_00712 1e-31 K Cro/C1-type HTH DNA-binding domain
CLAGIPMF_00713 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
CLAGIPMF_00714 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
CLAGIPMF_00715 1.1e-94
CLAGIPMF_00716 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CLAGIPMF_00717 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_00718 4e-47 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_00719 3.4e-186 S CRISPR-associated protein Csn2 subfamily St
CLAGIPMF_00720 3e-145 ycgQ S TIGR03943 family
CLAGIPMF_00721 8.4e-157 XK27_03015 S permease
CLAGIPMF_00723 0.0 yhgF K Transcriptional accessory protein
CLAGIPMF_00724 7.1e-40 pspC KT PspC domain
CLAGIPMF_00725 2.3e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLAGIPMF_00726 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLAGIPMF_00728 5.5e-69 ytxH S General stress protein
CLAGIPMF_00730 2e-177 yegQ O Peptidase U32
CLAGIPMF_00731 3.4e-252 yegQ O Peptidase U32
CLAGIPMF_00732 8.1e-46 S CHY zinc finger
CLAGIPMF_00733 8.4e-88 bioY S biotin synthase
CLAGIPMF_00735 1.1e-33 XK27_12190 S protein conserved in bacteria
CLAGIPMF_00736 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
CLAGIPMF_00737 4.8e-11
CLAGIPMF_00738 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
CLAGIPMF_00739 4.1e-225 mutH L DNA mismatch repair enzyme MutH
CLAGIPMF_00740 1.1e-07 S SIR2-like domain
CLAGIPMF_00741 1.2e-33 S SIR2-like domain
CLAGIPMF_00742 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CLAGIPMF_00743 1.8e-155 M LysM domain
CLAGIPMF_00744 5.9e-16
CLAGIPMF_00745 7.5e-174 S hydrolase
CLAGIPMF_00746 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
CLAGIPMF_00747 5.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLAGIPMF_00748 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
CLAGIPMF_00749 2.7e-27 P Hemerythrin HHE cation binding domain protein
CLAGIPMF_00750 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLAGIPMF_00751 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
CLAGIPMF_00752 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
CLAGIPMF_00753 2.4e-40 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CLAGIPMF_00754 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
CLAGIPMF_00755 1.6e-272 hsdM 2.1.1.72 V N-6 DNA Methylase
CLAGIPMF_00756 6.8e-103 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
CLAGIPMF_00758 8.2e-107
CLAGIPMF_00759 3.6e-169 spd F DNA RNA non-specific endonuclease
CLAGIPMF_00760 5.9e-92 lemA S LemA family
CLAGIPMF_00761 9.3e-132 htpX O Belongs to the peptidase M48B family
CLAGIPMF_00762 4.2e-75 S Psort location CytoplasmicMembrane, score
CLAGIPMF_00763 5.3e-55 S Domain of unknown function (DUF4430)
CLAGIPMF_00764 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CLAGIPMF_00765 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
CLAGIPMF_00766 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CLAGIPMF_00767 2.7e-160 L Transposase
CLAGIPMF_00768 3e-50 L Transposase
CLAGIPMF_00769 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CLAGIPMF_00770 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CLAGIPMF_00771 3.2e-92 dps P Belongs to the Dps family
CLAGIPMF_00772 1.1e-80 perR P Belongs to the Fur family
CLAGIPMF_00773 8.4e-28 yqgQ S protein conserved in bacteria
CLAGIPMF_00774 2.2e-179 glk 2.7.1.2 G Glucokinase
CLAGIPMF_00775 0.0 typA T GTP-binding protein TypA
CLAGIPMF_00777 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLAGIPMF_00778 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLAGIPMF_00779 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CLAGIPMF_00780 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CLAGIPMF_00781 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLAGIPMF_00782 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLAGIPMF_00783 6.8e-96 sepF D cell septum assembly
CLAGIPMF_00784 2.6e-34 yggT D integral membrane protein
CLAGIPMF_00785 4.2e-144 ylmH T S4 RNA-binding domain
CLAGIPMF_00786 1.8e-135 divIVA D Cell division protein DivIVA
CLAGIPMF_00787 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLAGIPMF_00788 5.5e-30
CLAGIPMF_00789 8.4e-10
CLAGIPMF_00790 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
CLAGIPMF_00791 2e-45 rpmE2 J 50S ribosomal protein L31
CLAGIPMF_00792 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CLAGIPMF_00793 3e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CLAGIPMF_00794 2.4e-155 gst O Glutathione S-transferase
CLAGIPMF_00795 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLAGIPMF_00796 4.5e-111 tdk 2.7.1.21 F thymidine kinase
CLAGIPMF_00797 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLAGIPMF_00798 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CLAGIPMF_00799 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CLAGIPMF_00800 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLAGIPMF_00801 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
CLAGIPMF_00802 2.4e-107 pvaA M lytic transglycosylase activity
CLAGIPMF_00803 0.0 yfiB1 V abc transporter atp-binding protein
CLAGIPMF_00804 0.0 XK27_10035 V abc transporter atp-binding protein
CLAGIPMF_00805 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
CLAGIPMF_00806 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLAGIPMF_00807 4.6e-238 dltB M Membrane protein involved in D-alanine export
CLAGIPMF_00808 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLAGIPMF_00809 1.5e-228 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLAGIPMF_00810 4.1e-181 L Transposase
CLAGIPMF_00811 5.7e-47 L Transposase
CLAGIPMF_00812 0.0 3.6.3.8 P cation transport ATPase
CLAGIPMF_00813 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CLAGIPMF_00814 5.1e-106 V Abi-like protein
CLAGIPMF_00815 7.6e-140 2.1.1.37 H cytosine-specific methyltransferase
CLAGIPMF_00816 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
CLAGIPMF_00817 3e-44 ymbI L transposase activity
CLAGIPMF_00818 4e-22 L Belongs to the 'phage' integrase family
CLAGIPMF_00819 1.4e-66 S tRNA_anti-like
CLAGIPMF_00820 2e-103
CLAGIPMF_00822 2.3e-12
CLAGIPMF_00824 2e-296 S DNA primase
CLAGIPMF_00825 3e-164 KL Phage plasmid primase P4 family
CLAGIPMF_00826 6.9e-22
CLAGIPMF_00831 5.5e-17 K TRANSCRIPTIONal
CLAGIPMF_00832 6e-39 K Helix-turn-helix
CLAGIPMF_00833 7.1e-217 sip L Belongs to the 'phage' integrase family
CLAGIPMF_00835 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLAGIPMF_00836 7.3e-166 metF 1.5.1.20 E reductase
CLAGIPMF_00837 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CLAGIPMF_00838 1.7e-94 panT S ECF transporter, substrate-specific component
CLAGIPMF_00839 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLAGIPMF_00840 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CLAGIPMF_00841 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CLAGIPMF_00842 8.8e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLAGIPMF_00843 1.6e-40 T PhoQ Sensor
CLAGIPMF_00844 3.2e-42 T PhoQ Sensor
CLAGIPMF_00845 4.3e-124 T PhoQ Sensor
CLAGIPMF_00846 3.9e-122 L Transposase
CLAGIPMF_00847 1.2e-165 L integrase core domain
CLAGIPMF_00848 2.1e-30 rpsT J rRNA binding
CLAGIPMF_00849 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
CLAGIPMF_00850 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
CLAGIPMF_00851 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CLAGIPMF_00852 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CLAGIPMF_00853 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLAGIPMF_00854 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLAGIPMF_00855 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CLAGIPMF_00856 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CLAGIPMF_00857 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CLAGIPMF_00858 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
CLAGIPMF_00859 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
CLAGIPMF_00860 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CLAGIPMF_00861 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CLAGIPMF_00862 3.1e-81 ypmB S Protein conserved in bacteria
CLAGIPMF_00863 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CLAGIPMF_00864 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CLAGIPMF_00865 1.5e-07
CLAGIPMF_00866 8.7e-38 L Transposase
CLAGIPMF_00867 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CLAGIPMF_00868 7.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLAGIPMF_00869 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
CLAGIPMF_00870 7.2e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CLAGIPMF_00871 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
CLAGIPMF_00872 7.3e-20 D nuclear chromosome segregation
CLAGIPMF_00873 5.3e-136 yejC S cyclic nucleotide-binding protein
CLAGIPMF_00874 1.2e-163 rapZ S Displays ATPase and GTPase activities
CLAGIPMF_00875 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CLAGIPMF_00876 8.7e-162 whiA K May be required for sporulation
CLAGIPMF_00877 2.4e-167 pepD E Dipeptidase
CLAGIPMF_00878 5.4e-32 cspD K Cold shock protein domain
CLAGIPMF_00879 1.1e-250 L Transposase
CLAGIPMF_00880 9.4e-43 K Cold-Shock Protein
CLAGIPMF_00881 1.3e-94 L Transposase
CLAGIPMF_00882 6.4e-90 L Transposase
CLAGIPMF_00883 0.0 copB 3.6.3.4 P P-type ATPase
CLAGIPMF_00884 9.7e-222 L Transposase, Mutator family
CLAGIPMF_00885 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CLAGIPMF_00886 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CLAGIPMF_00887 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CLAGIPMF_00888 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
CLAGIPMF_00889 6.6e-94 L Transposase
CLAGIPMF_00890 7.1e-89 L Transposase
CLAGIPMF_00891 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
CLAGIPMF_00892 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
CLAGIPMF_00893 4.1e-156 glcU U Glucose uptake
CLAGIPMF_00894 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
CLAGIPMF_00895 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
CLAGIPMF_00896 2.2e-101 XK27_10720 D peptidase activity
CLAGIPMF_00897 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
CLAGIPMF_00898 1.7e-08
CLAGIPMF_00900 1.2e-165 L integrase core domain
CLAGIPMF_00901 3.9e-122 L Transposase
CLAGIPMF_00902 2.1e-172 yeiH S Membrane
CLAGIPMF_00903 4.7e-109 mur1 NU muramidase
CLAGIPMF_00904 1.6e-19 L transposase activity
CLAGIPMF_00905 4.3e-70 L transposition
CLAGIPMF_00906 4.5e-166 cpsY K Transcriptional regulator
CLAGIPMF_00907 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CLAGIPMF_00908 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
CLAGIPMF_00909 4e-105 artQ P ABC transporter (Permease
CLAGIPMF_00910 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_00911 1.2e-157 aatB ET ABC transporter substrate-binding protein
CLAGIPMF_00912 1.8e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLAGIPMF_00913 2.1e-07
CLAGIPMF_00914 3.4e-58 adhP 1.1.1.1 C alcohol dehydrogenase
CLAGIPMF_00915 1.5e-23 adhP 1.1.1.1 C alcohol dehydrogenase
CLAGIPMF_00916 4.7e-17 adhP 1.1.1.1 C alcohol dehydrogenase
CLAGIPMF_00917 5e-31 adhP 1.1.1.1 C alcohol dehydrogenase
CLAGIPMF_00919 1.1e-20
CLAGIPMF_00920 0.0 res_1 3.1.21.5 S Type III restriction
CLAGIPMF_00921 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
CLAGIPMF_00922 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CLAGIPMF_00923 2e-126 gntR1 K transcriptional
CLAGIPMF_00924 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLAGIPMF_00925 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLAGIPMF_00926 2.4e-87 niaX
CLAGIPMF_00927 7.8e-91 niaR S small molecule binding protein (contains 3H domain)
CLAGIPMF_00928 1.6e-128 K DNA-binding helix-turn-helix protein
CLAGIPMF_00929 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLAGIPMF_00930 2.7e-28 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLAGIPMF_00931 3.3e-68 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLAGIPMF_00932 9.7e-115 GK ROK family
CLAGIPMF_00933 8.3e-159 dprA LU DNA protecting protein DprA
CLAGIPMF_00934 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLAGIPMF_00935 1.4e-150 S TraX protein
CLAGIPMF_00936 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLAGIPMF_00937 2.4e-251 T PhoQ Sensor
CLAGIPMF_00938 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CLAGIPMF_00939 1.9e-152 XK27_05470 E Methionine synthase
CLAGIPMF_00940 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CLAGIPMF_00941 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLAGIPMF_00942 6.8e-51 IQ Acetoin reductase
CLAGIPMF_00943 3.9e-19 IQ Acetoin reductase
CLAGIPMF_00944 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CLAGIPMF_00948 4.1e-53 K peptidyl-tyrosine sulfation
CLAGIPMF_00949 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CLAGIPMF_00952 1.3e-212 pqqE C radical SAM domain protein
CLAGIPMF_00953 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
CLAGIPMF_00954 1.1e-60 EGP Major facilitator Superfamily
CLAGIPMF_00955 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CLAGIPMF_00956 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CLAGIPMF_00957 7.6e-225 L Transposase
CLAGIPMF_00958 2.7e-116 V ABC transporter (Permease
CLAGIPMF_00959 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CLAGIPMF_00960 1.6e-10
CLAGIPMF_00961 9e-98 K Transcriptional regulator, TetR family
CLAGIPMF_00962 1.8e-159 czcD P cation diffusion facilitator family transporter
CLAGIPMF_00963 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CLAGIPMF_00964 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
CLAGIPMF_00965 6e-08 S Hydrolases of the alpha beta superfamily
CLAGIPMF_00966 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
CLAGIPMF_00967 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
CLAGIPMF_00970 2.6e-143 2.4.2.3 F Phosphorylase superfamily
CLAGIPMF_00971 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
CLAGIPMF_00972 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
CLAGIPMF_00973 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
CLAGIPMF_00974 8.8e-55 dinF V Mate efflux family protein
CLAGIPMF_00975 6.3e-12 dinF V Mate efflux family protein
CLAGIPMF_00977 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CLAGIPMF_00979 1.6e-101 S TraX protein
CLAGIPMF_00980 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CLAGIPMF_00981 3.7e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CLAGIPMF_00982 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CLAGIPMF_00983 4.7e-185 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_00984 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_00985 2.6e-132 cas6 S CRISPR-associated endoribonuclease Cas6
CLAGIPMF_00986 7.3e-107 csm1 S CRISPR-associated protein Csm1 family
CLAGIPMF_00987 2.2e-37 csm2 L Csm2 Type III-A
CLAGIPMF_00988 9.9e-115 csm3 L RAMP superfamily
CLAGIPMF_00989 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
CLAGIPMF_00990 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
CLAGIPMF_00991 2.1e-14 csm6 S Psort location Cytoplasmic, score
CLAGIPMF_00992 5.2e-74 csm6 S Psort location Cytoplasmic, score
CLAGIPMF_00993 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CLAGIPMF_00994 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLAGIPMF_00995 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
CLAGIPMF_00997 7.9e-266 dtpT E transporter
CLAGIPMF_00998 2.9e-103 nylA 3.5.1.4 J Belongs to the amidase family
CLAGIPMF_00999 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
CLAGIPMF_01000 1.8e-67 yecS P ABC transporter (Permease
CLAGIPMF_01002 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CLAGIPMF_01003 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
CLAGIPMF_01004 1.4e-104 yfiF3 K sequence-specific DNA binding
CLAGIPMF_01005 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLAGIPMF_01006 1.8e-240 agcS E (Alanine) symporter
CLAGIPMF_01007 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CLAGIPMF_01008 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
CLAGIPMF_01009 1.8e-59 Q phosphatase activity
CLAGIPMF_01010 9.3e-62 S haloacid dehalogenase-like hydrolase
CLAGIPMF_01011 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLAGIPMF_01012 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CLAGIPMF_01013 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
CLAGIPMF_01014 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
CLAGIPMF_01015 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLAGIPMF_01016 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CLAGIPMF_01017 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CLAGIPMF_01018 1.9e-43 yktA S Belongs to the UPF0223 family
CLAGIPMF_01019 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CLAGIPMF_01020 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CLAGIPMF_01021 3.3e-158 pstS P phosphate
CLAGIPMF_01022 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CLAGIPMF_01023 5.9e-155 pstA P phosphate transport system permease
CLAGIPMF_01024 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLAGIPMF_01025 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLAGIPMF_01026 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
CLAGIPMF_01027 0.0 pepN 3.4.11.2 E aminopeptidase
CLAGIPMF_01028 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CLAGIPMF_01029 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
CLAGIPMF_01031 3.7e-09
CLAGIPMF_01032 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CLAGIPMF_01033 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CLAGIPMF_01034 2.3e-23 L Transposase
CLAGIPMF_01035 4.6e-25 tatA U protein secretion
CLAGIPMF_01036 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLAGIPMF_01037 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CLAGIPMF_01038 5.6e-233 ycdB P peroxidase
CLAGIPMF_01039 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
CLAGIPMF_01040 2.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
CLAGIPMF_01041 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
CLAGIPMF_01042 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAGIPMF_01043 1.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLAGIPMF_01044 5.5e-36 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01045 3.7e-160 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01046 4.4e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01047 1.2e-292 3.5.1.28 NU amidase activity
CLAGIPMF_01048 0.0 lpdA 1.8.1.4 C Dehydrogenase
CLAGIPMF_01049 5.1e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLAGIPMF_01050 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CLAGIPMF_01051 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CLAGIPMF_01052 5e-38 P membrane protein (DUF2207)
CLAGIPMF_01053 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01054 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CLAGIPMF_01055 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLAGIPMF_01056 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLAGIPMF_01057 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_01058 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_01059 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_01060 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
CLAGIPMF_01061 1.1e-158 rssA S Phospholipase, patatin family
CLAGIPMF_01062 1e-105 estA E Lysophospholipase L1 and related esterases
CLAGIPMF_01063 2e-291 S unusual protein kinase
CLAGIPMF_01064 4.9e-39 S granule-associated protein
CLAGIPMF_01065 2.3e-34 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CLAGIPMF_01066 9.3e-42 bglH 3.2.1.86 GT1 G beta-glucosidase activity
CLAGIPMF_01067 1.3e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CLAGIPMF_01068 2.9e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
CLAGIPMF_01069 1.3e-17 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CLAGIPMF_01070 1.3e-199 S hmm pf01594
CLAGIPMF_01071 6.2e-44 G alpha-ribazole phosphatase activity
CLAGIPMF_01072 1.8e-79 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CLAGIPMF_01073 2.2e-94 V VanZ like family
CLAGIPMF_01074 1.5e-152 L Transposase
CLAGIPMF_01075 3.8e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
CLAGIPMF_01076 3e-159 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLAGIPMF_01077 2.2e-199 cps1C S Polysaccharide biosynthesis protein
CLAGIPMF_01078 7.5e-14 cps3F
CLAGIPMF_01079 3.3e-184 cps1B GT2,GT4 M Glycosyl transferases group 1
CLAGIPMF_01080 1.1e-103 sacB GT2,GT4 M transferase activity, transferring glycosyl groups
CLAGIPMF_01082 3.6e-145 M Glycosyltransferase, group 2 family protein
CLAGIPMF_01083 2.5e-115 Z012_10770 M Domain of unknown function (DUF1919)
CLAGIPMF_01084 7.8e-208 wcoF M Glycosyltransferase, group 1 family protein
CLAGIPMF_01085 4.2e-217 rgpAc GT4 M group 1 family protein
CLAGIPMF_01086 1.4e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CLAGIPMF_01087 3.2e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
CLAGIPMF_01088 2.6e-105 cps4C M biosynthesis protein
CLAGIPMF_01089 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CLAGIPMF_01090 8e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CLAGIPMF_01091 4.5e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CLAGIPMF_01092 1.2e-121 yfeJ 6.3.5.2 F glutamine amidotransferase
CLAGIPMF_01093 7.3e-41 clcA_2 P chloride
CLAGIPMF_01094 2.2e-42 clcA_2 P chloride channel
CLAGIPMF_01095 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CLAGIPMF_01096 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLAGIPMF_01097 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLAGIPMF_01099 6.1e-22 V Glucan-binding protein C
CLAGIPMF_01100 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
CLAGIPMF_01101 2.4e-275 pepV 3.5.1.18 E Dipeptidase
CLAGIPMF_01102 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CLAGIPMF_01103 1.7e-47 XK27_03610 K Gnat family
CLAGIPMF_01104 1.6e-24 L Transposase
CLAGIPMF_01105 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLAGIPMF_01106 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CLAGIPMF_01107 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLAGIPMF_01108 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CLAGIPMF_01109 3.9e-15 M LysM domain
CLAGIPMF_01110 2.9e-90 ebsA S Family of unknown function (DUF5322)
CLAGIPMF_01111 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CLAGIPMF_01112 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CLAGIPMF_01113 4.9e-224 G COG0457 FOG TPR repeat
CLAGIPMF_01114 1.1e-175 yubA S permease
CLAGIPMF_01115 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CLAGIPMF_01116 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CLAGIPMF_01117 2.5e-124 ftsE D cell division ATP-binding protein FtsE
CLAGIPMF_01118 6.3e-174 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLAGIPMF_01119 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLAGIPMF_01120 1.3e-181 yjjH S Calcineurin-like phosphoesterase
CLAGIPMF_01121 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CLAGIPMF_01122 0.0 pacL 3.6.3.8 P cation transport ATPase
CLAGIPMF_01123 2.6e-67 ywiB S Domain of unknown function (DUF1934)
CLAGIPMF_01124 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
CLAGIPMF_01125 9.2e-147 yidA S hydrolases of the HAD superfamily
CLAGIPMF_01126 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CLAGIPMF_01127 5e-35 F Protein of unknown function (DUF454)
CLAGIPMF_01128 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CLAGIPMF_01129 1.9e-234 vicK 2.7.13.3 T Histidine kinase
CLAGIPMF_01130 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLAGIPMF_01131 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_01132 1.3e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CLAGIPMF_01133 8e-115 gltJ P ABC transporter (Permease
CLAGIPMF_01134 4.2e-110 tcyB_2 P ABC transporter (permease)
CLAGIPMF_01135 2.4e-124 endA F DNA RNA non-specific endonuclease
CLAGIPMF_01136 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
CLAGIPMF_01137 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLAGIPMF_01139 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLAGIPMF_01140 5.9e-26 G Domain of unknown function (DUF4832)
CLAGIPMF_01141 1.3e-202 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLAGIPMF_01142 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CLAGIPMF_01143 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLAGIPMF_01144 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CLAGIPMF_01145 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLAGIPMF_01146 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
CLAGIPMF_01149 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CLAGIPMF_01150 3.4e-217 XK27_05110 P chloride
CLAGIPMF_01151 9.6e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CLAGIPMF_01152 1.3e-282 clcA P Chloride transporter, ClC family
CLAGIPMF_01153 2.3e-75 fld C Flavodoxin
CLAGIPMF_01154 3.3e-14 XK27_08880
CLAGIPMF_01155 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
CLAGIPMF_01156 1.6e-151 estA CE1 S Putative esterase
CLAGIPMF_01157 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLAGIPMF_01158 4.4e-135 XK27_08845 S abc transporter atp-binding protein
CLAGIPMF_01159 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CLAGIPMF_01160 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
CLAGIPMF_01162 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01163 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01166 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CLAGIPMF_01167 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CLAGIPMF_01168 0.0 dnaE 2.7.7.7 L DNA polymerase
CLAGIPMF_01169 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
CLAGIPMF_01170 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLAGIPMF_01171 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLAGIPMF_01172 2.5e-43 ysdA L Membrane
CLAGIPMF_01173 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CLAGIPMF_01174 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLAGIPMF_01175 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLAGIPMF_01176 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CLAGIPMF_01178 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CLAGIPMF_01179 5.1e-83 ypmS S Protein conserved in bacteria
CLAGIPMF_01180 3.9e-143 ypmR E lipolytic protein G-D-S-L family
CLAGIPMF_01181 3e-148 DegV S DegV family
CLAGIPMF_01182 9.9e-305 recN L May be involved in recombinational repair of damaged DNA
CLAGIPMF_01183 1.8e-72 argR K Regulates arginine biosynthesis genes
CLAGIPMF_01184 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CLAGIPMF_01185 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CLAGIPMF_01186 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
CLAGIPMF_01187 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLAGIPMF_01189 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLAGIPMF_01190 3.8e-125 dnaD
CLAGIPMF_01191 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLAGIPMF_01192 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLAGIPMF_01193 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CLAGIPMF_01194 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CLAGIPMF_01195 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CLAGIPMF_01196 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CLAGIPMF_01197 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLAGIPMF_01198 5.6e-240 rodA D Belongs to the SEDS family
CLAGIPMF_01199 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
CLAGIPMF_01200 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLAGIPMF_01201 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CLAGIPMF_01202 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLAGIPMF_01203 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLAGIPMF_01204 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CLAGIPMF_01205 1.2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLAGIPMF_01206 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CLAGIPMF_01207 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLAGIPMF_01208 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLAGIPMF_01210 6.6e-31 L Integrase core domain protein
CLAGIPMF_01211 1.6e-55 L transposition
CLAGIPMF_01212 8.2e-22 L Transposase
CLAGIPMF_01213 5.2e-36 L transposase activity
CLAGIPMF_01214 1.3e-22 XK27_08085
CLAGIPMF_01215 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CLAGIPMF_01216 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CLAGIPMF_01217 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CLAGIPMF_01218 1.1e-121 ylfI S tigr01906
CLAGIPMF_01219 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CLAGIPMF_01220 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
CLAGIPMF_01221 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
CLAGIPMF_01224 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CLAGIPMF_01225 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CLAGIPMF_01226 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLAGIPMF_01227 1.1e-206 yurR 1.4.5.1 E oxidoreductase
CLAGIPMF_01228 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
CLAGIPMF_01229 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLAGIPMF_01230 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CLAGIPMF_01231 1.3e-70 gtrA S GtrA-like protein
CLAGIPMF_01232 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLAGIPMF_01233 2.3e-168 ybbR S Protein conserved in bacteria
CLAGIPMF_01234 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLAGIPMF_01235 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CLAGIPMF_01236 8.7e-150 cobQ S glutamine amidotransferase
CLAGIPMF_01237 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLAGIPMF_01238 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
CLAGIPMF_01239 6.3e-13 MA20_06245 S yiaA/B two helix domain
CLAGIPMF_01241 0.0 uup S abc transporter atp-binding protein
CLAGIPMF_01242 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CLAGIPMF_01243 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
CLAGIPMF_01244 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CLAGIPMF_01245 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CLAGIPMF_01246 1.6e-249 L Transposase
CLAGIPMF_01247 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLAGIPMF_01248 7.9e-39 ptsH G phosphocarrier protein Hpr
CLAGIPMF_01249 5.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
CLAGIPMF_01250 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
CLAGIPMF_01251 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLAGIPMF_01252 2.2e-34 nrdH O Glutaredoxin
CLAGIPMF_01253 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLAGIPMF_01254 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLAGIPMF_01256 4.2e-71 L Transposase (IS116 IS110 IS902 family)
CLAGIPMF_01257 8.8e-60 L Transposase (IS116 IS110 IS902 family)
CLAGIPMF_01258 5.3e-165 ypuA S secreted protein
CLAGIPMF_01259 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
CLAGIPMF_01260 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CLAGIPMF_01261 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLAGIPMF_01262 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CLAGIPMF_01263 3.4e-258 noxE P NADH oxidase
CLAGIPMF_01264 1.9e-294 yfmM S abc transporter atp-binding protein
CLAGIPMF_01265 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
CLAGIPMF_01266 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CLAGIPMF_01267 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CLAGIPMF_01268 2e-86 S ECF-type riboflavin transporter, S component
CLAGIPMF_01270 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLAGIPMF_01271 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CLAGIPMF_01274 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLAGIPMF_01275 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLAGIPMF_01276 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLAGIPMF_01277 0.0 smc D Required for chromosome condensation and partitioning
CLAGIPMF_01278 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CLAGIPMF_01279 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLAGIPMF_01280 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLAGIPMF_01281 6.1e-87 alkD L Dna alkylation repair
CLAGIPMF_01282 2.4e-92 pat 2.3.1.183 M acetyltransferase
CLAGIPMF_01283 1.5e-12
CLAGIPMF_01284 3.1e-30
CLAGIPMF_01285 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLAGIPMF_01286 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CLAGIPMF_01287 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CLAGIPMF_01288 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
CLAGIPMF_01289 2.4e-29 sdaAA 4.3.1.17 E L-serine dehydratase
CLAGIPMF_01290 3.5e-101 sdaAA 4.3.1.17 E L-serine dehydratase
CLAGIPMF_01291 2.3e-27
CLAGIPMF_01292 3.8e-106 S ABC-2 family transporter protein
CLAGIPMF_01293 3.5e-33 S transport system, permease component
CLAGIPMF_01294 3.6e-97 S transport system, permease component
CLAGIPMF_01295 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLAGIPMF_01296 1.5e-192 desK 2.7.13.3 T Histidine kinase
CLAGIPMF_01297 1.4e-133 yvfS V ABC-2 type transporter
CLAGIPMF_01298 8.7e-159 XK27_09825 V abc transporter atp-binding protein
CLAGIPMF_01301 3.6e-163 yocS S Transporter
CLAGIPMF_01302 3.1e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
CLAGIPMF_01303 7.5e-115 yvfS V Transporter
CLAGIPMF_01304 2.7e-152 XK27_09825 V abc transporter atp-binding protein
CLAGIPMF_01305 2.3e-09 liaI KT membrane
CLAGIPMF_01307 2.6e-30 liaI KT membrane
CLAGIPMF_01308 6.1e-93 XK27_05000 S metal cluster binding
CLAGIPMF_01309 0.0 V ABC transporter (permease)
CLAGIPMF_01310 1.9e-133 macB2 V ABC transporter, ATP-binding protein
CLAGIPMF_01311 6.2e-166 T Histidine kinase
CLAGIPMF_01312 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLAGIPMF_01313 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CLAGIPMF_01314 3.3e-69 pbuX F xanthine permease
CLAGIPMF_01315 9.2e-119 pbuX F xanthine permease
CLAGIPMF_01316 4.5e-247 norM V Multidrug efflux pump
CLAGIPMF_01317 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLAGIPMF_01318 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
CLAGIPMF_01319 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
CLAGIPMF_01320 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
CLAGIPMF_01321 4.8e-25 csbD K CsbD-like
CLAGIPMF_01322 1.8e-227 yfnA E amino acid
CLAGIPMF_01323 3.7e-228 S dextransucrase activity
CLAGIPMF_01324 1.1e-139 S dextransucrase activity
CLAGIPMF_01325 1.6e-21 L Integrase core domain protein
CLAGIPMF_01328 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_01329 3e-114 yxeN P ABC transporter, permease protein
CLAGIPMF_01330 6.1e-107 ytmL P ABC transporter (Permease
CLAGIPMF_01331 1.8e-161 ET ABC transporter substrate-binding protein
CLAGIPMF_01332 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
CLAGIPMF_01333 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CLAGIPMF_01334 2.4e-40 S Sugar efflux transporter for intercellular exchange
CLAGIPMF_01335 5.9e-23 P FtsX-like permease family
CLAGIPMF_01336 3.2e-91 V abc transporter atp-binding protein
CLAGIPMF_01337 3.9e-82 K WHG domain
CLAGIPMF_01338 9.4e-68 ydhF S Aldo keto reductase
CLAGIPMF_01339 2.1e-71 ydhF S Aldo keto reductase
CLAGIPMF_01341 5.7e-109 XK27_02070 S nitroreductase
CLAGIPMF_01342 1.5e-138 1.13.11.2 S glyoxalase
CLAGIPMF_01343 5.6e-77 ywnA K Transcriptional regulator
CLAGIPMF_01344 6.1e-157 E Alpha/beta hydrolase of unknown function (DUF915)
CLAGIPMF_01345 1.6e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLAGIPMF_01346 2.2e-111 drgA C Nitroreductase
CLAGIPMF_01347 6.6e-102 yoaK S Protein of unknown function (DUF1275)
CLAGIPMF_01349 1.5e-160 yvgN C reductase
CLAGIPMF_01350 1.3e-131 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLAGIPMF_01351 1.4e-13 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLAGIPMF_01352 1.4e-13 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLAGIPMF_01353 3.9e-284 XK27_07020 S Belongs to the UPF0371 family
CLAGIPMF_01355 1.1e-35 BP1961 P nitric oxide dioxygenase activity
CLAGIPMF_01356 4.2e-27 K response regulator
CLAGIPMF_01357 3.6e-15 KT the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01358 1.3e-30 S Signal peptide protein, YSIRK family
CLAGIPMF_01360 1.6e-58
CLAGIPMF_01361 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLAGIPMF_01362 1.9e-35
CLAGIPMF_01363 4e-20
CLAGIPMF_01364 1.5e-24 IQ PFAM AMP-dependent synthetase and ligase
CLAGIPMF_01365 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
CLAGIPMF_01366 5.8e-109 MA20_06410 E LysE type translocator
CLAGIPMF_01367 5.6e-08
CLAGIPMF_01368 2.7e-09
CLAGIPMF_01369 0.0 M family 8
CLAGIPMF_01371 3.8e-161 hrtB V MacB-like periplasmic core domain
CLAGIPMF_01372 4.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
CLAGIPMF_01373 1.1e-151 V MatE
CLAGIPMF_01375 3.9e-110 C Fe-S oxidoreductases
CLAGIPMF_01376 1.2e-176 EGP Major Facilitator Superfamily
CLAGIPMF_01377 5.5e-258 I radical SAM domain protein
CLAGIPMF_01379 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CLAGIPMF_01380 1.4e-150 L Integrase core domain protein
CLAGIPMF_01381 1.8e-87 L transposase activity
CLAGIPMF_01383 2.8e-85
CLAGIPMF_01384 0.0 sbcC L ATPase involved in DNA repair
CLAGIPMF_01385 1.4e-228 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CLAGIPMF_01386 0.0 lacL 3.2.1.23 G -beta-galactosidase
CLAGIPMF_01387 0.0 lacS G transporter
CLAGIPMF_01388 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CLAGIPMF_01389 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CLAGIPMF_01390 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CLAGIPMF_01391 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLAGIPMF_01392 2.3e-184 galR K Transcriptional regulator
CLAGIPMF_01393 2.7e-08 L Integrase core domain protein
CLAGIPMF_01394 1.2e-25 L transposition
CLAGIPMF_01395 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CLAGIPMF_01396 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CLAGIPMF_01397 1.2e-100 V abc transporter atp-binding protein
CLAGIPMF_01398 1e-41 V (ABC) transporter
CLAGIPMF_01399 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CLAGIPMF_01400 6.4e-62 L Transposase
CLAGIPMF_01401 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01402 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01403 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01404 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CLAGIPMF_01405 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CLAGIPMF_01406 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CLAGIPMF_01407 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLAGIPMF_01410 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLAGIPMF_01411 1.7e-174 vraS 2.7.13.3 T Histidine kinase
CLAGIPMF_01412 3.7e-120 yvqF KT membrane
CLAGIPMF_01413 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CLAGIPMF_01414 2e-132 stp 3.1.3.16 T phosphatase
CLAGIPMF_01415 2.2e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLAGIPMF_01416 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLAGIPMF_01417 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLAGIPMF_01418 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CLAGIPMF_01419 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CLAGIPMF_01420 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CLAGIPMF_01421 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
CLAGIPMF_01422 2.1e-148 supH S overlaps another CDS with the same product name
CLAGIPMF_01423 8.6e-63 yvoA_1 K Transcriptional
CLAGIPMF_01424 2.8e-120 skfE V abc transporter atp-binding protein
CLAGIPMF_01425 3.3e-133 V ATPase activity
CLAGIPMF_01426 4.3e-172 oppF P Belongs to the ABC transporter superfamily
CLAGIPMF_01427 2.2e-204 oppD P Belongs to the ABC transporter superfamily
CLAGIPMF_01428 4.9e-168 amiD P ABC transporter (Permease
CLAGIPMF_01429 1.2e-272 amiC P ABC transporter (Permease
CLAGIPMF_01430 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CLAGIPMF_01431 8.1e-45 L Transposase
CLAGIPMF_01432 4.1e-158 L COG2801 Transposase and inactivated derivatives
CLAGIPMF_01433 1.2e-24 oppF P Belongs to the ABC transporter superfamily
CLAGIPMF_01434 5e-45 oppF P Belongs to the ABC transporter superfamily
CLAGIPMF_01435 1.4e-40 tatD L Hydrolase, tatd
CLAGIPMF_01436 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
CLAGIPMF_01437 1e-110 L Integrase core domain protein
CLAGIPMF_01438 1.1e-23 L transposase activity
CLAGIPMF_01439 8.9e-18 L transposase activity
CLAGIPMF_01440 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CLAGIPMF_01441 1.7e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CLAGIPMF_01442 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLAGIPMF_01443 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CLAGIPMF_01444 1.5e-103 yjbK S Adenylate cyclase
CLAGIPMF_01445 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLAGIPMF_01446 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
CLAGIPMF_01447 3.1e-59 XK27_04120 S Putative amino acid metabolism
CLAGIPMF_01448 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLAGIPMF_01449 7.9e-131 puuD T peptidase C26
CLAGIPMF_01450 6.2e-120 radC E Belongs to the UPF0758 family
CLAGIPMF_01451 3.4e-273 rgpF M Rhamnan synthesis protein F
CLAGIPMF_01452 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CLAGIPMF_01453 6.4e-140 rgpC GM Transport permease protein
CLAGIPMF_01454 4.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
CLAGIPMF_01455 9.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
CLAGIPMF_01456 5.6e-254 S Glucosyl transferase GtrII
CLAGIPMF_01457 3.5e-214 GT4 M transferase activity, transferring glycosyl groups
CLAGIPMF_01458 1.2e-217 M Psort location CytoplasmicMembrane, score
CLAGIPMF_01459 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
CLAGIPMF_01460 5.5e-47 S Psort location CytoplasmicMembrane, score
CLAGIPMF_01461 1.1e-35 S Psort location CytoplasmicMembrane, score
CLAGIPMF_01462 4.2e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
CLAGIPMF_01463 4.6e-42 S Uncharacterized conserved protein (DUF2304)
CLAGIPMF_01464 1.4e-127 arnC M group 2 family protein
CLAGIPMF_01465 3.1e-144 M Glycosyl transferase family 8
CLAGIPMF_01467 1.1e-187 glf 5.4.99.9 M UDP-galactopyranose mutase
CLAGIPMF_01468 2.2e-154 S Polysaccharide biosynthesis protein
CLAGIPMF_01469 2.6e-87 M Psort location Cytoplasmic, score
CLAGIPMF_01470 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CLAGIPMF_01471 1.5e-209 S Predicted membrane protein (DUF2142)
CLAGIPMF_01472 2.2e-168 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CLAGIPMF_01473 5.9e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CLAGIPMF_01474 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CLAGIPMF_01475 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CLAGIPMF_01476 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CLAGIPMF_01477 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
CLAGIPMF_01478 1.4e-201 arcT 2.6.1.1 E Aminotransferase
CLAGIPMF_01479 2.5e-136 ET ABC transporter
CLAGIPMF_01480 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
CLAGIPMF_01481 2.9e-84 mutT 3.6.1.55 F Nudix family
CLAGIPMF_01482 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CLAGIPMF_01483 2.5e-56 V CAAX protease self-immunity
CLAGIPMF_01484 2.4e-33 S CAAX amino terminal protease family protein
CLAGIPMF_01485 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CLAGIPMF_01486 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_01487 1.1e-16 XK27_00735
CLAGIPMF_01488 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLAGIPMF_01490 6.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CLAGIPMF_01493 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
CLAGIPMF_01494 6.6e-30 ycaO O OsmC-like protein
CLAGIPMF_01496 1.2e-22 EG Permeases of the drug metabolite transporter (DMT) superfamily
CLAGIPMF_01497 3.4e-154 L Integrase core domain protein
CLAGIPMF_01498 7.8e-40 L Transposase
CLAGIPMF_01499 1.6e-103 EG Permeases of the drug metabolite transporter (DMT) superfamily
CLAGIPMF_01501 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
CLAGIPMF_01502 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_01503 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CLAGIPMF_01504 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CLAGIPMF_01505 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
CLAGIPMF_01506 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CLAGIPMF_01507 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLAGIPMF_01508 2.6e-109 3.1.3.18 S IA, variant 1
CLAGIPMF_01509 2.2e-117 lrgB M effector of murein hydrolase
CLAGIPMF_01510 2.2e-58 lrgA S Effector of murein hydrolase LrgA
CLAGIPMF_01512 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
CLAGIPMF_01513 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
CLAGIPMF_01514 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLAGIPMF_01515 3.9e-104 wecD M Acetyltransferase GNAT family
CLAGIPMF_01516 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLAGIPMF_01517 2.6e-95 GK ROK family
CLAGIPMF_01518 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
CLAGIPMF_01519 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
CLAGIPMF_01520 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
CLAGIPMF_01521 2.3e-206 potD P spermidine putrescine ABC transporter
CLAGIPMF_01522 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
CLAGIPMF_01523 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
CLAGIPMF_01524 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CLAGIPMF_01525 7.8e-171 murB 1.3.1.98 M cell wall formation
CLAGIPMF_01526 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLAGIPMF_01527 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLAGIPMF_01528 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CLAGIPMF_01529 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLAGIPMF_01530 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
CLAGIPMF_01531 0.0 ydaO E amino acid
CLAGIPMF_01532 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CLAGIPMF_01533 4.1e-37 ylqC L Belongs to the UPF0109 family
CLAGIPMF_01534 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CLAGIPMF_01535 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CLAGIPMF_01536 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
CLAGIPMF_01537 2.1e-74 S QueT transporter
CLAGIPMF_01538 1.9e-55 L Transposase
CLAGIPMF_01539 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CLAGIPMF_01540 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLAGIPMF_01541 3.7e-85 ccl S cog cog4708
CLAGIPMF_01542 4.8e-163 rbn E Belongs to the UPF0761 family
CLAGIPMF_01543 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CLAGIPMF_01544 3.3e-231 ytoI K transcriptional regulator containing CBS domains
CLAGIPMF_01545 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CLAGIPMF_01546 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLAGIPMF_01547 0.0 comEC S Competence protein ComEC
CLAGIPMF_01548 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CLAGIPMF_01549 8.3e-142 plsC 2.3.1.51 I Acyltransferase
CLAGIPMF_01550 1.7e-77 nodB3 G polysaccharide deacetylase
CLAGIPMF_01551 4.1e-22 nodB3 G polysaccharide deacetylase
CLAGIPMF_01552 2.3e-139 yabB 2.1.1.223 L Methyltransferase
CLAGIPMF_01553 1e-41 yazA L endonuclease containing a URI domain
CLAGIPMF_01554 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CLAGIPMF_01555 2.3e-154 corA P CorA-like protein
CLAGIPMF_01556 1.9e-62 yjqA S Bacterial PH domain
CLAGIPMF_01557 7.8e-100 thiT S Thiamine transporter
CLAGIPMF_01558 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CLAGIPMF_01559 1.6e-200 yjbB G Permeases of the major facilitator superfamily
CLAGIPMF_01560 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CLAGIPMF_01561 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
CLAGIPMF_01562 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CLAGIPMF_01566 4.3e-155 cjaA ET ABC transporter substrate-binding protein
CLAGIPMF_01567 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_01568 3e-106 P ABC transporter (Permease
CLAGIPMF_01569 6e-115 papP P ABC transporter (Permease
CLAGIPMF_01570 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CLAGIPMF_01571 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
CLAGIPMF_01572 0.0 copA 3.6.3.54 P P-type ATPase
CLAGIPMF_01573 1.8e-72 copY K Copper transport repressor, CopY TcrY family
CLAGIPMF_01574 4.3e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CLAGIPMF_01575 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CLAGIPMF_01576 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CLAGIPMF_01577 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CLAGIPMF_01578 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLAGIPMF_01579 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CLAGIPMF_01580 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLAGIPMF_01581 1.6e-55
CLAGIPMF_01582 0.0 ctpE P E1-E2 ATPase
CLAGIPMF_01583 1.6e-27
CLAGIPMF_01584 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLAGIPMF_01585 5.1e-47 L transposase activity
CLAGIPMF_01586 5.3e-119 K transcriptional regulator, MerR family
CLAGIPMF_01587 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
CLAGIPMF_01588 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
CLAGIPMF_01589 7.4e-64 XK27_02560 S cog cog2151
CLAGIPMF_01590 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CLAGIPMF_01591 7.7e-227 ytfP S Flavoprotein
CLAGIPMF_01593 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CLAGIPMF_01594 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
CLAGIPMF_01595 4.6e-183 ecsB U ABC transporter
CLAGIPMF_01596 2.3e-133 ecsA V abc transporter atp-binding protein
CLAGIPMF_01597 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CLAGIPMF_01598 5.6e-12
CLAGIPMF_01599 2.6e-55 S CD20-like family
CLAGIPMF_01600 7.3e-107
CLAGIPMF_01601 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CLAGIPMF_01602 1.3e-204 ylbM S Belongs to the UPF0348 family
CLAGIPMF_01603 4.5e-140 yqeM Q Methyltransferase domain protein
CLAGIPMF_01604 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CLAGIPMF_01605 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CLAGIPMF_01606 2.7e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLAGIPMF_01607 3.5e-49 yhbY J RNA-binding protein
CLAGIPMF_01608 6.4e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CLAGIPMF_01609 1.8e-98 yqeG S hydrolase of the HAD superfamily
CLAGIPMF_01610 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CLAGIPMF_01611 1.4e-65
CLAGIPMF_01612 1.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLAGIPMF_01613 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CLAGIPMF_01614 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLAGIPMF_01615 1e-21 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CLAGIPMF_01616 5.2e-256 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CLAGIPMF_01617 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLAGIPMF_01618 6.3e-154 hlpA M Belongs to the NlpA lipoprotein family
CLAGIPMF_01619 6.8e-101 pncA Q isochorismatase
CLAGIPMF_01620 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CLAGIPMF_01621 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CLAGIPMF_01622 4.4e-74 XK27_03180 T universal stress protein
CLAGIPMF_01624 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLAGIPMF_01625 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CLAGIPMF_01626 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CLAGIPMF_01627 0.0 yjcE P NhaP-type Na H and K H antiporters
CLAGIPMF_01629 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
CLAGIPMF_01630 1.3e-184 yhcC S radical SAM protein
CLAGIPMF_01631 2.2e-196 ylbL T Belongs to the peptidase S16 family
CLAGIPMF_01632 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLAGIPMF_01633 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
CLAGIPMF_01634 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CLAGIPMF_01635 6.1e-08 S Protein of unknown function (DUF4059)
CLAGIPMF_01636 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
CLAGIPMF_01637 1.4e-159 yxeN P ABC transporter (Permease
CLAGIPMF_01638 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CLAGIPMF_01640 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLAGIPMF_01641 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CLAGIPMF_01642 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
CLAGIPMF_01643 5.1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLAGIPMF_01644 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
CLAGIPMF_01645 2.9e-87 D nuclear chromosome segregation
CLAGIPMF_01646 1.5e-127 ybbM S transport system, permease component
CLAGIPMF_01647 1.2e-117 ybbL S abc transporter atp-binding protein
CLAGIPMF_01648 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CLAGIPMF_01649 4.6e-140 cppA E CppA N-terminal
CLAGIPMF_01650 5e-44 V CAAX protease self-immunity
CLAGIPMF_01651 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CLAGIPMF_01652 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CLAGIPMF_01655 2.9e-28 blpT
CLAGIPMF_01656 6.7e-98 blpT
CLAGIPMF_01657 3.9e-122 L Transposase
CLAGIPMF_01658 1.2e-165 L integrase core domain
CLAGIPMF_01663 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
CLAGIPMF_01666 8.9e-133 agrA KT phosphorelay signal transduction system
CLAGIPMF_01667 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
CLAGIPMF_01669 7.3e-237 mesE M Transport protein ComB
CLAGIPMF_01670 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CLAGIPMF_01671 0.0 mdlB V abc transporter atp-binding protein
CLAGIPMF_01672 0.0 mdlA V abc transporter atp-binding protein
CLAGIPMF_01674 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
CLAGIPMF_01675 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CLAGIPMF_01676 2.3e-72 yutD J protein conserved in bacteria
CLAGIPMF_01677 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CLAGIPMF_01679 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CLAGIPMF_01680 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLAGIPMF_01681 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CLAGIPMF_01682 8.1e-46 ftsL D cell division protein FtsL
CLAGIPMF_01683 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CLAGIPMF_01684 3e-128
CLAGIPMF_01685 9.7e-32 yhaI J Protein of unknown function (DUF805)
CLAGIPMF_01686 1.3e-08 D nuclear chromosome segregation
CLAGIPMF_01687 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLAGIPMF_01688 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLAGIPMF_01689 2.2e-285 XK27_00765
CLAGIPMF_01690 8.1e-134 ecsA_2 V abc transporter atp-binding protein
CLAGIPMF_01691 5.2e-125 S Protein of unknown function (DUF554)
CLAGIPMF_01692 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CLAGIPMF_01693 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CLAGIPMF_01694 9.8e-57 liaI S membrane
CLAGIPMF_01695 7e-10 XK27_02470 K LytTr DNA-binding domain protein
CLAGIPMF_01696 1.8e-65 KT response to antibiotic
CLAGIPMF_01697 5.2e-81 yebC M Membrane
CLAGIPMF_01698 2.9e-18 yebC M Membrane
CLAGIPMF_01699 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
CLAGIPMF_01700 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CLAGIPMF_01701 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLAGIPMF_01702 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLAGIPMF_01703 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CLAGIPMF_01704 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLAGIPMF_01705 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLAGIPMF_01706 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CLAGIPMF_01708 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
CLAGIPMF_01709 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CLAGIPMF_01710 0.0 scrA 2.7.1.211 G pts system
CLAGIPMF_01711 4.1e-291 scrB 3.2.1.26 GH32 G invertase
CLAGIPMF_01712 1.7e-179 scrR K Transcriptional
CLAGIPMF_01713 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLAGIPMF_01714 3.4e-62 yqhY S protein conserved in bacteria
CLAGIPMF_01715 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLAGIPMF_01716 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
CLAGIPMF_01717 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CLAGIPMF_01719 8e-44 V 'abc transporter, ATP-binding protein
CLAGIPMF_01720 1e-58 V 'abc transporter, ATP-binding protein
CLAGIPMF_01723 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLAGIPMF_01724 2e-169 corA P COG0598 Mg2 and Co2 transporters
CLAGIPMF_01725 3.1e-124 XK27_01040 S Pfam PF06570
CLAGIPMF_01727 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLAGIPMF_01728 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CLAGIPMF_01729 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
CLAGIPMF_01730 3.6e-41 XK27_05745
CLAGIPMF_01731 2.5e-230 mutY L A G-specific adenine glycosylase
CLAGIPMF_01736 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLAGIPMF_01737 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CLAGIPMF_01738 1e-93 cvpA S toxin biosynthetic process
CLAGIPMF_01739 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLAGIPMF_01740 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLAGIPMF_01741 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CLAGIPMF_01742 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CLAGIPMF_01743 8.8e-48 azlD E branched-chain amino acid
CLAGIPMF_01744 1.8e-114 azlC E AzlC protein
CLAGIPMF_01745 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLAGIPMF_01746 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CLAGIPMF_01747 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CLAGIPMF_01748 2.5e-33 ykzG S Belongs to the UPF0356 family
CLAGIPMF_01749 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLAGIPMF_01750 2.7e-40 pscB M CHAP domain protein
CLAGIPMF_01751 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
CLAGIPMF_01752 8.5e-63 glnR K Transcriptional regulator
CLAGIPMF_01753 1.3e-87 S Fusaric acid resistance protein-like
CLAGIPMF_01754 1.1e-12
CLAGIPMF_01755 8.9e-30
CLAGIPMF_01756 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CLAGIPMF_01757 3.2e-42 L Transposase
CLAGIPMF_01758 1.9e-46 L transposase activity
CLAGIPMF_01759 7.4e-23 L Transposase
CLAGIPMF_01760 4.2e-53 L transposition
CLAGIPMF_01761 9.1e-83 L Integrase core domain protein
CLAGIPMF_01762 1e-102 L Transposase
CLAGIPMF_01763 4.8e-111 L Transposase
CLAGIPMF_01764 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CLAGIPMF_01765 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLAGIPMF_01766 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CLAGIPMF_01767 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLAGIPMF_01768 5.3e-142 purR 2.4.2.7 F operon repressor
CLAGIPMF_01769 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
CLAGIPMF_01770 1.5e-172 rmuC S RmuC domain protein
CLAGIPMF_01771 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
CLAGIPMF_01772 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CLAGIPMF_01773 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CLAGIPMF_01775 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CLAGIPMF_01776 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLAGIPMF_01777 1.6e-143 tatD L Hydrolase, tatd
CLAGIPMF_01778 7.2e-74 yccU S CoA-binding protein
CLAGIPMF_01779 4.8e-51 trxA O Belongs to the thioredoxin family
CLAGIPMF_01780 1.9e-141 S Macro domain protein
CLAGIPMF_01781 2e-09 L thioesterase
CLAGIPMF_01782 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
CLAGIPMF_01785 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CLAGIPMF_01786 5e-84 L Transposase
CLAGIPMF_01787 1e-13 rpmH J Ribosomal protein L34
CLAGIPMF_01788 2e-186 jag S RNA-binding protein
CLAGIPMF_01789 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLAGIPMF_01790 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CLAGIPMF_01791 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
CLAGIPMF_01792 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CLAGIPMF_01793 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLAGIPMF_01794 6.7e-81 amiA E transmembrane transport
CLAGIPMF_01795 7.3e-69 amiA E transmembrane transport
CLAGIPMF_01796 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CLAGIPMF_01797 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLAGIPMF_01798 9.2e-51 S Protein of unknown function (DUF3397)
CLAGIPMF_01799 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CLAGIPMF_01800 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
CLAGIPMF_01801 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
CLAGIPMF_01802 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLAGIPMF_01803 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CLAGIPMF_01804 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
CLAGIPMF_01805 6.2e-76 XK27_09620 S reductase
CLAGIPMF_01806 1.5e-220 XK27_09615 C reductase
CLAGIPMF_01807 2.5e-116 fnt P Formate nitrite transporter
CLAGIPMF_01808 1.3e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
CLAGIPMF_01809 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CLAGIPMF_01810 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CLAGIPMF_01811 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CLAGIPMF_01812 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLAGIPMF_01813 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CLAGIPMF_01814 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CLAGIPMF_01815 1.9e-46 S glycolate biosynthetic process
CLAGIPMF_01816 1.5e-64 S phosphatase activity
CLAGIPMF_01817 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
CLAGIPMF_01820 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CLAGIPMF_01821 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CLAGIPMF_01822 1.9e-36 yeeD O sulfur carrier activity
CLAGIPMF_01823 2e-109 yeeE S Sulphur transport
CLAGIPMF_01824 2.6e-68 yeeE S Sulphur transport
CLAGIPMF_01825 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLAGIPMF_01826 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CLAGIPMF_01827 4.1e-09 S Domain of unknown function (DUF4651)
CLAGIPMF_01828 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CLAGIPMF_01829 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLAGIPMF_01830 8.7e-111 S CAAX amino terminal protease family protein
CLAGIPMF_01832 1.1e-66 V CAAX protease self-immunity
CLAGIPMF_01833 8e-34 V CAAX protease self-immunity
CLAGIPMF_01834 2.6e-26 lanR K sequence-specific DNA binding
CLAGIPMF_01835 3.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLAGIPMF_01836 2.9e-176 ytxK 2.1.1.72 L DNA methylase
CLAGIPMF_01837 5.2e-13 comGF U Putative Competence protein ComGF
CLAGIPMF_01838 1.3e-70 comGF U Competence protein ComGF
CLAGIPMF_01839 3.2e-15 NU Type II secretory pathway pseudopilin
CLAGIPMF_01840 3e-57 cglD NU Competence protein
CLAGIPMF_01841 8.5e-43 comGC U Required for transformation and DNA binding
CLAGIPMF_01842 3e-145 cglB NU type II secretion system
CLAGIPMF_01843 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLAGIPMF_01844 2.9e-68 S cog cog4699
CLAGIPMF_01845 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLAGIPMF_01846 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLAGIPMF_01847 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CLAGIPMF_01848 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLAGIPMF_01849 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLAGIPMF_01850 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
CLAGIPMF_01851 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CLAGIPMF_01852 1e-284 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CLAGIPMF_01853 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CLAGIPMF_01854 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
CLAGIPMF_01855 1.8e-57 asp S cog cog1302
CLAGIPMF_01856 3.2e-226 norN V Mate efflux family protein
CLAGIPMF_01857 1.2e-277 thrC 4.2.3.1 E Threonine synthase
CLAGIPMF_01858 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CLAGIPMF_01859 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CLAGIPMF_01860 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CLAGIPMF_01861 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CLAGIPMF_01862 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
CLAGIPMF_01863 0.0 pepO 3.4.24.71 O Peptidase family M13
CLAGIPMF_01864 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CLAGIPMF_01865 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CLAGIPMF_01866 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CLAGIPMF_01867 1.4e-54 treB 2.7.1.201 G PTS System
CLAGIPMF_01868 5.8e-21 treR K DNA-binding transcription factor activity
CLAGIPMF_01869 1.2e-85 treR K trehalose operon
CLAGIPMF_01870 3.3e-95 ywlG S Belongs to the UPF0340 family
CLAGIPMF_01873 2e-35 L PFAM Integrase, catalytic core
CLAGIPMF_01874 2e-94 L PFAM Integrase, catalytic core
CLAGIPMF_01875 3.3e-46 K Putative DNA-binding domain
CLAGIPMF_01876 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
CLAGIPMF_01877 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLAGIPMF_01878 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01883 1e-39
CLAGIPMF_01884 6.5e-31
CLAGIPMF_01885 5e-31 S Hypothetical protein (DUF2513)
CLAGIPMF_01886 7.7e-13
CLAGIPMF_01888 5.7e-217 S MvaI/BcnI restriction endonuclease family
CLAGIPMF_01890 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
CLAGIPMF_01891 4.5e-163 fba 4.1.2.13, 4.1.2.29 G aldolase
CLAGIPMF_01893 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
CLAGIPMF_01894 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
CLAGIPMF_01895 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
CLAGIPMF_01896 3.3e-09 L PFAM Integrase, catalytic core
CLAGIPMF_01897 1.8e-111 L PFAM Integrase, catalytic core
CLAGIPMF_01898 3.3e-62 rplQ J ribosomal protein l17
CLAGIPMF_01899 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLAGIPMF_01900 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLAGIPMF_01901 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLAGIPMF_01902 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CLAGIPMF_01903 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLAGIPMF_01904 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CLAGIPMF_01905 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CLAGIPMF_01906 4.4e-58 rplO J binds to the 23S rRNA
CLAGIPMF_01907 2.5e-23 rpmD J ribosomal protein l30
CLAGIPMF_01908 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLAGIPMF_01909 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLAGIPMF_01910 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLAGIPMF_01911 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLAGIPMF_01912 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLAGIPMF_01913 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLAGIPMF_01914 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLAGIPMF_01915 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLAGIPMF_01916 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLAGIPMF_01917 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CLAGIPMF_01918 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLAGIPMF_01919 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLAGIPMF_01920 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLAGIPMF_01921 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLAGIPMF_01922 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLAGIPMF_01923 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CLAGIPMF_01924 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CLAGIPMF_01925 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLAGIPMF_01926 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CLAGIPMF_01927 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CLAGIPMF_01928 0.0 XK27_09800 I Acyltransferase
CLAGIPMF_01929 1.7e-35 XK27_09805 S MORN repeat protein
CLAGIPMF_01930 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLAGIPMF_01931 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLAGIPMF_01932 1.5e-89 adk 2.7.4.3 F topology modulation protein
CLAGIPMF_01933 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CLAGIPMF_01934 7e-127 Z012_04635 K sequence-specific DNA binding
CLAGIPMF_01936 6.3e-16 C Radical SAM
CLAGIPMF_01937 3.4e-191 C Radical SAM
CLAGIPMF_01938 3.9e-287 V ABC transporter transmembrane region
CLAGIPMF_01939 2.5e-89 K sequence-specific DNA binding
CLAGIPMF_01940 1.3e-36 L Replication initiation factor
CLAGIPMF_01941 1.4e-107 L Replication initiation factor
CLAGIPMF_01942 1.9e-18 S Domain of unknown function (DUF3173)
CLAGIPMF_01943 3.5e-216 int L Belongs to the 'phage' integrase family
CLAGIPMF_01945 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CLAGIPMF_01946 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CLAGIPMF_01947 2.8e-44 yrzL S Belongs to the UPF0297 family
CLAGIPMF_01948 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLAGIPMF_01949 4.2e-44 yrzB S Belongs to the UPF0473 family
CLAGIPMF_01950 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
CLAGIPMF_01951 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CLAGIPMF_01952 7.5e-14
CLAGIPMF_01953 2.6e-91 XK27_10930 K acetyltransferase
CLAGIPMF_01954 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLAGIPMF_01955 1.8e-147 yaaA S Belongs to the UPF0246 family
CLAGIPMF_01956 9.3e-167 XK27_01785 S cog cog1284
CLAGIPMF_01957 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CLAGIPMF_01959 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
CLAGIPMF_01960 1.4e-53 metE 2.1.1.14 E Methionine synthase
CLAGIPMF_01961 5.2e-55 metE 2.1.1.14 E Methionine synthase
CLAGIPMF_01962 1.4e-36 metE 2.1.1.14 E Methionine synthase
CLAGIPMF_01963 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CLAGIPMF_01964 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CLAGIPMF_01967 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
CLAGIPMF_01968 2.5e-96 S Hydrophobic domain protein
CLAGIPMF_01970 1e-29 S Membrane
CLAGIPMF_01971 9.1e-101
CLAGIPMF_01972 1.8e-23 S Small integral membrane protein
CLAGIPMF_01973 3.1e-85 M Protein conserved in bacteria
CLAGIPMF_01974 1.1e-11 K CsbD-like
CLAGIPMF_01975 3.4e-13 nudL L hydrolase
CLAGIPMF_01976 4e-19 K negative regulation of transcription, DNA-templated
CLAGIPMF_01977 1.7e-23 K negative regulation of transcription, DNA-templated
CLAGIPMF_01979 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
CLAGIPMF_01980 1.8e-88 S Putative adhesin
CLAGIPMF_01981 3.9e-161 XK27_06930 V domain protein
CLAGIPMF_01982 6.4e-96 XK27_06935 K transcriptional regulator
CLAGIPMF_01983 4.8e-55 ypaA M Membrane
CLAGIPMF_01984 2.7e-08
CLAGIPMF_01985 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLAGIPMF_01986 8.2e-48 veg S Biofilm formation stimulator VEG
CLAGIPMF_01987 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CLAGIPMF_01988 3.9e-70 rplI J binds to the 23S rRNA
CLAGIPMF_01989 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CLAGIPMF_01990 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CLAGIPMF_01991 1.5e-77 F NUDIX domain
CLAGIPMF_01992 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CLAGIPMF_01993 0.0 S Bacterial membrane protein, YfhO
CLAGIPMF_01994 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
CLAGIPMF_01995 5.3e-85 lytE M LysM domain protein
CLAGIPMF_01996 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLAGIPMF_01997 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLAGIPMF_01998 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLAGIPMF_01999 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLAGIPMF_02000 6.3e-138 ymfM S sequence-specific DNA binding
CLAGIPMF_02001 1.2e-241 ymfH S Peptidase M16
CLAGIPMF_02002 1.3e-156 ymfF S Peptidase M16
CLAGIPMF_02003 1.7e-66 ymfF S Peptidase M16
CLAGIPMF_02004 1.6e-45 yaaA S S4 domain protein YaaA
CLAGIPMF_02005 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLAGIPMF_02006 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CLAGIPMF_02007 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CLAGIPMF_02008 4.2e-153 yvjA S membrane
CLAGIPMF_02009 3.3e-305 ybiT S abc transporter atp-binding protein
CLAGIPMF_02010 0.0 XK27_10405 S Bacterial membrane protein YfhO
CLAGIPMF_02014 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
CLAGIPMF_02015 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLAGIPMF_02016 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CLAGIPMF_02017 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)