ORF_ID e_value Gene_name EC_number CAZy COGs Description
NGEPNEPM_00001 1.6e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NGEPNEPM_00002 7.7e-200 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NGEPNEPM_00003 1.1e-29 yyzM S Protein conserved in bacteria
NGEPNEPM_00004 7.3e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NGEPNEPM_00005 1.2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NGEPNEPM_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NGEPNEPM_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NGEPNEPM_00008 5.1e-60 divIC D Septum formation initiator
NGEPNEPM_00010 2.2e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NGEPNEPM_00011 9.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NGEPNEPM_00012 3.8e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NGEPNEPM_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NGEPNEPM_00014 3.2e-148 L Transposase
NGEPNEPM_00015 1.6e-45 L Transposase
NGEPNEPM_00016 5e-35 L transposase activity
NGEPNEPM_00017 1.4e-22 L Transposase
NGEPNEPM_00018 2.9e-31 L transposition
NGEPNEPM_00019 1.3e-37 L Integrase core domain protein
NGEPNEPM_00020 7.2e-30 L Integrase core domain protein
NGEPNEPM_00033 5.3e-11
NGEPNEPM_00039 3e-137 mreC M Involved in formation and maintenance of cell shape
NGEPNEPM_00040 3.1e-87 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NGEPNEPM_00041 2.8e-90 usp 3.5.1.28 CBM50 S CHAP domain
NGEPNEPM_00042 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGEPNEPM_00043 2.5e-26
NGEPNEPM_00044 5.9e-219 araT 2.6.1.1 E Aminotransferase
NGEPNEPM_00045 5e-142 recO L Involved in DNA repair and RecF pathway recombination
NGEPNEPM_00046 5.1e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NGEPNEPM_00047 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGEPNEPM_00048 7.6e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NGEPNEPM_00049 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGEPNEPM_00050 3.3e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NGEPNEPM_00051 9.1e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NGEPNEPM_00052 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NGEPNEPM_00053 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NGEPNEPM_00054 6.8e-79 L transposase activity
NGEPNEPM_00055 8.3e-84 L Integrase core domain protein
NGEPNEPM_00056 1.9e-158 S CHAP domain
NGEPNEPM_00057 2e-241 purD 6.3.4.13 F Belongs to the GARS family
NGEPNEPM_00058 5.9e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NGEPNEPM_00059 2.5e-203 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NGEPNEPM_00060 2e-140 1.1.1.169 H Ketopantoate reductase
NGEPNEPM_00061 1.9e-33
NGEPNEPM_00062 3.9e-136 J Domain of unknown function (DUF4041)
NGEPNEPM_00064 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NGEPNEPM_00065 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NGEPNEPM_00066 8.2e-70 argR K Regulates arginine biosynthesis genes
NGEPNEPM_00067 2.3e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NGEPNEPM_00068 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NGEPNEPM_00069 3e-78 S Protein of unknown function (DUF3021)
NGEPNEPM_00071 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NGEPNEPM_00073 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NGEPNEPM_00074 7.8e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NGEPNEPM_00075 3e-229 cinA 3.5.1.42 S Belongs to the CinA family
NGEPNEPM_00076 3e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NGEPNEPM_00077 3.7e-64 spxA_2 1.20.4.1 P Belongs to the ArsC family
NGEPNEPM_00078 4e-234 L Transposase
NGEPNEPM_00084 2.6e-10
NGEPNEPM_00087 1.9e-07
NGEPNEPM_00092 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGEPNEPM_00093 1.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NGEPNEPM_00094 5.5e-36 XK27_02060 S Transglycosylase associated protein
NGEPNEPM_00095 5e-67 badR K Transcriptional regulator, marr family
NGEPNEPM_00096 6.1e-94 S reductase
NGEPNEPM_00097 1.6e-149 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NGEPNEPM_00098 5.4e-09 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NGEPNEPM_00100 4.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
NGEPNEPM_00101 3.6e-180 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NGEPNEPM_00102 6e-82 S Putative small multi-drug export protein
NGEPNEPM_00103 1.3e-73 ctsR K Belongs to the CtsR family
NGEPNEPM_00104 0.0 clpC O Belongs to the ClpA ClpB family
NGEPNEPM_00105 3.7e-235 L Transposase
NGEPNEPM_00106 2.7e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NGEPNEPM_00107 9.9e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NGEPNEPM_00108 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NGEPNEPM_00109 5e-142 S SseB protein N-terminal domain
NGEPNEPM_00110 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NGEPNEPM_00111 6.6e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NGEPNEPM_00112 8e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NGEPNEPM_00115 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGEPNEPM_00116 1.6e-91 yacP S RNA-binding protein containing a PIN domain
NGEPNEPM_00117 9.8e-155 degV S DegV family
NGEPNEPM_00118 1.1e-27 K helix-turn-helix
NGEPNEPM_00119 1.8e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NGEPNEPM_00120 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NGEPNEPM_00121 8.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NGEPNEPM_00122 3e-146 L Phage integrase, N-terminal SAM-like domain
NGEPNEPM_00123 9.6e-35 S Helix-turn-helix domain
NGEPNEPM_00124 9.5e-139 S Psort location Cytoplasmic, score 8.87
NGEPNEPM_00125 2.2e-53
NGEPNEPM_00126 3.4e-47
NGEPNEPM_00127 3e-124
NGEPNEPM_00128 1.1e-90 K Response regulator receiver domain protein
NGEPNEPM_00129 9.8e-105 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NGEPNEPM_00130 6.2e-123 potA3 V ABC transporter
NGEPNEPM_00131 6.2e-70 S ABC-2 family transporter protein
NGEPNEPM_00132 5.9e-49 int L Belongs to the 'phage' integrase family
NGEPNEPM_00133 1.2e-113 int L Belongs to the 'phage' integrase family
NGEPNEPM_00134 8.7e-41 S Helix-turn-helix domain
NGEPNEPM_00135 1.3e-114
NGEPNEPM_00137 1.7e-74 isp2 S pathogenesis
NGEPNEPM_00138 9.2e-124 tnp L DDE domain
NGEPNEPM_00139 4.8e-246 G polysaccharide deacetylase
NGEPNEPM_00140 5.5e-65 dhaL 2.7.1.121 G Dihydroxyacetone kinase
NGEPNEPM_00141 7.1e-124 tnp L Transposase IS66 family
NGEPNEPM_00142 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
NGEPNEPM_00143 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NGEPNEPM_00144 1.2e-123 tnp L Transposase IS66 family
NGEPNEPM_00145 7e-40 S Filamentation induced by cAMP protein fic
NGEPNEPM_00146 1.9e-107 K Cro/C1-type HTH DNA-binding domain
NGEPNEPM_00147 2.7e-35 bcrA V ABC transporter
NGEPNEPM_00148 4.1e-125 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
NGEPNEPM_00149 9.8e-127 S ABC-2 family transporter protein
NGEPNEPM_00150 1.1e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NGEPNEPM_00151 4.7e-128 tnp L Transposase
NGEPNEPM_00152 6.3e-12 S Conjugative transposon protein TcpC
NGEPNEPM_00153 0.0 tetP J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NGEPNEPM_00154 1.3e-76 tnp L Transposase
NGEPNEPM_00155 4.4e-21 tnp L Transposase
NGEPNEPM_00156 1.2e-222 capA M Bacterial capsule synthesis protein
NGEPNEPM_00157 6.1e-39 gcvR T UPF0237 protein
NGEPNEPM_00158 5.1e-243 XK27_08635 S UPF0210 protein
NGEPNEPM_00159 3.5e-134 ais G Phosphoglycerate mutase
NGEPNEPM_00160 7e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NGEPNEPM_00161 1.4e-99 acmA 3.2.1.17 NU amidase activity
NGEPNEPM_00162 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NGEPNEPM_00163 6.2e-67 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NGEPNEPM_00164 1.7e-286 dnaK O Heat shock 70 kDa protein
NGEPNEPM_00165 5.7e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NGEPNEPM_00166 4.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NGEPNEPM_00167 3.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NGEPNEPM_00168 1.9e-72 hmpT S cog cog4720
NGEPNEPM_00171 8.8e-215 L Transposase
NGEPNEPM_00172 1.6e-77 sigH K DNA-templated transcription, initiation
NGEPNEPM_00173 1.1e-145 ykuT M mechanosensitive ion channel
NGEPNEPM_00174 2.3e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NGEPNEPM_00175 1.1e-72 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NGEPNEPM_00176 1.6e-307 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NGEPNEPM_00177 6e-82 XK27_03960 S Protein of unknown function (DUF3013)
NGEPNEPM_00178 8.5e-78 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NGEPNEPM_00179 8e-174 prmA J Ribosomal protein L11 methyltransferase
NGEPNEPM_00180 1.2e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NGEPNEPM_00181 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NGEPNEPM_00182 2.6e-82 nrdI F Belongs to the NrdI family
NGEPNEPM_00183 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NGEPNEPM_00184 2.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NGEPNEPM_00185 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NGEPNEPM_00186 7.2e-37 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NGEPNEPM_00187 1.4e-07 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NGEPNEPM_00188 2e-25 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NGEPNEPM_00189 7.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NGEPNEPM_00190 6.2e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NGEPNEPM_00191 3.5e-109 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NGEPNEPM_00192 5.1e-199 yhjX P Major Facilitator
NGEPNEPM_00193 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NGEPNEPM_00194 8.8e-91 V VanZ like family
NGEPNEPM_00196 1.8e-130 D nuclear chromosome segregation
NGEPNEPM_00197 7e-39 D nuclear chromosome segregation
NGEPNEPM_00198 3.8e-123 glnQ E abc transporter atp-binding protein
NGEPNEPM_00199 4.5e-275 glnP P ABC transporter
NGEPNEPM_00200 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NGEPNEPM_00201 8.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NGEPNEPM_00202 2.1e-184 tagO 2.7.8.33, 2.7.8.35 M transferase
NGEPNEPM_00203 1.4e-234 L Transposase
NGEPNEPM_00204 2.1e-143 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NGEPNEPM_00205 2e-233 sufD O assembly protein SufD
NGEPNEPM_00206 6.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NGEPNEPM_00207 4.7e-73 nifU C SUF system FeS assembly protein, NifU family
NGEPNEPM_00208 4.7e-271 sufB O assembly protein SufB
NGEPNEPM_00209 3.7e-304 oppA E ABC transporter substrate-binding protein
NGEPNEPM_00210 2.4e-159 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NGEPNEPM_00211 1.2e-162 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NGEPNEPM_00212 7.3e-189 oppD P Belongs to the ABC transporter superfamily
NGEPNEPM_00213 8.1e-163 oppF P Belongs to the ABC transporter superfamily
NGEPNEPM_00215 5.6e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NGEPNEPM_00216 2.1e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NGEPNEPM_00217 6e-128 K sequence-specific DNA binding
NGEPNEPM_00218 0.0 KLT serine threonine protein kinase
NGEPNEPM_00219 3.2e-223 EGP Major facilitator Superfamily
NGEPNEPM_00220 3.1e-72 adcR K transcriptional
NGEPNEPM_00221 6e-134 adcC P ABC transporter, ATP-binding protein
NGEPNEPM_00222 1.1e-128 adcB P ABC transporter (Permease
NGEPNEPM_00223 4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NGEPNEPM_00224 0.0 ptsG 2.7.1.199, 2.7.1.208 G pts system
NGEPNEPM_00225 9e-150 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NGEPNEPM_00226 2.2e-254 pgi 5.3.1.9 G Belongs to the GPI family
NGEPNEPM_00227 1.1e-124 yeeN K transcriptional regulatory protein
NGEPNEPM_00228 2.2e-49 yajC U protein transport
NGEPNEPM_00229 1.2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NGEPNEPM_00230 4.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
NGEPNEPM_00231 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NGEPNEPM_00232 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NGEPNEPM_00233 0.0 WQ51_06230 S ABC transporter substrate binding protein
NGEPNEPM_00234 3.7e-140 cmpC S abc transporter atp-binding protein
NGEPNEPM_00235 1.7e-39 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NGEPNEPM_00236 3.6e-283 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NGEPNEPM_00237 1.6e-83 L Transposase
NGEPNEPM_00238 7.2e-104 L Transposase
NGEPNEPM_00239 5.9e-28 K Transcriptional regulator
NGEPNEPM_00240 1.8e-09
NGEPNEPM_00241 1.1e-38 3.5.2.6 V Beta-lactamase
NGEPNEPM_00242 4.2e-61 S very-long-chain-acyl-CoA dehydrogenase activity
NGEPNEPM_00243 3.9e-71
NGEPNEPM_00245 1.6e-70 nosF V abc transporter atp-binding protein
NGEPNEPM_00246 8.4e-17
NGEPNEPM_00247 2.4e-135 V ABC transporter
NGEPNEPM_00248 1.9e-107 CP ABC-2 family transporter protein
NGEPNEPM_00249 5e-135 1.6.5.5 C NADPH:quinone reductase activity
NGEPNEPM_00250 5.4e-69 L Transposase
NGEPNEPM_00251 6e-28 L Transposase
NGEPNEPM_00252 7.1e-34 L the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_00253 2.3e-26
NGEPNEPM_00256 9.4e-44
NGEPNEPM_00257 1.7e-54 S TM2 domain
NGEPNEPM_00258 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NGEPNEPM_00259 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NGEPNEPM_00260 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NGEPNEPM_00261 1.3e-24 secE U Belongs to the SecE SEC61-gamma family
NGEPNEPM_00262 4.2e-95 nusG K Participates in transcription elongation, termination and antitermination
NGEPNEPM_00263 5.7e-83 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NGEPNEPM_00264 7e-44 cof Q phosphatase activity
NGEPNEPM_00265 1.9e-31 cof Q phosphatase activity
NGEPNEPM_00266 1.5e-86 glcR K transcriptional regulator (DeoR family)
NGEPNEPM_00267 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NGEPNEPM_00269 5.5e-198 S COG1073 Hydrolases of the alpha beta superfamily
NGEPNEPM_00270 3.5e-274 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NGEPNEPM_00271 7.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NGEPNEPM_00272 1.2e-76 yhaI L Membrane
NGEPNEPM_00273 1.7e-259 pepC 3.4.22.40 E aminopeptidase
NGEPNEPM_00274 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NGEPNEPM_00275 6.9e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NGEPNEPM_00276 4.9e-93 ypsA S Belongs to the UPF0398 family
NGEPNEPM_00277 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NGEPNEPM_00278 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NGEPNEPM_00279 3.2e-280 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NGEPNEPM_00280 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NGEPNEPM_00281 4.1e-21
NGEPNEPM_00282 6.4e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NGEPNEPM_00283 1.4e-50 XK27_09675 K -acetyltransferase
NGEPNEPM_00284 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NGEPNEPM_00285 1e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NGEPNEPM_00286 1.9e-35 L Transposase and inactivated derivatives
NGEPNEPM_00287 1.8e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGEPNEPM_00288 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NGEPNEPM_00289 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGEPNEPM_00290 4.6e-88 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NGEPNEPM_00291 3.3e-97 ybhL S Belongs to the BI1 family
NGEPNEPM_00294 5.8e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NGEPNEPM_00295 5.3e-90 K transcriptional regulator
NGEPNEPM_00296 7.6e-36 yneF S UPF0154 protein
NGEPNEPM_00297 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NGEPNEPM_00298 1.6e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NGEPNEPM_00299 2.3e-98 XK27_09740 S Phosphoesterase
NGEPNEPM_00300 6.6e-84 ykuL S CBS domain
NGEPNEPM_00301 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NGEPNEPM_00302 1.2e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NGEPNEPM_00303 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NGEPNEPM_00304 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NGEPNEPM_00305 4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NGEPNEPM_00306 4.8e-255 trkH P Cation transport protein
NGEPNEPM_00307 5.5e-245 trkA P Potassium transporter peripheral membrane component
NGEPNEPM_00308 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NGEPNEPM_00309 1e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NGEPNEPM_00310 2.9e-111 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NGEPNEPM_00311 1.8e-226 L Transposase
NGEPNEPM_00312 3.6e-160 K sequence-specific DNA binding
NGEPNEPM_00313 6.4e-92 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGEPNEPM_00314 6e-93 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGEPNEPM_00315 3.9e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGEPNEPM_00316 6.2e-49 yhaI L Membrane
NGEPNEPM_00317 1e-35 S Domain of unknown function (DUF4173)
NGEPNEPM_00318 8.9e-95 ureI S AmiS/UreI family transporter
NGEPNEPM_00319 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NGEPNEPM_00320 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NGEPNEPM_00321 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NGEPNEPM_00322 2.5e-77 ureE O enzyme active site formation
NGEPNEPM_00323 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NGEPNEPM_00324 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NGEPNEPM_00325 2.2e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NGEPNEPM_00326 3.5e-177 cbiM P PDGLE domain
NGEPNEPM_00327 1.7e-137 P cobalt transport protein
NGEPNEPM_00328 1.5e-129 cbiO P ABC transporter
NGEPNEPM_00329 4.3e-131 ET ABC transporter substrate-binding protein
NGEPNEPM_00330 5.8e-158 metQ M Belongs to the NlpA lipoprotein family
NGEPNEPM_00331 1.8e-256 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NGEPNEPM_00332 1.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NGEPNEPM_00333 1.7e-96 metI P ABC transporter (Permease
NGEPNEPM_00334 8.7e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NGEPNEPM_00335 7.6e-83 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NGEPNEPM_00336 2.4e-59 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NGEPNEPM_00337 4.1e-41 S UPF0397 protein
NGEPNEPM_00338 4.8e-103 ykoD P abc transporter atp-binding protein
NGEPNEPM_00339 6.8e-179 ykoD P abc transporter atp-binding protein
NGEPNEPM_00340 4.2e-147 cbiQ P cobalt transport
NGEPNEPM_00341 1.4e-234 L Transposase
NGEPNEPM_00342 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NGEPNEPM_00343 3.3e-118 ktrA P COG0569 K transport systems, NAD-binding component
NGEPNEPM_00344 1.1e-240 P COG0168 Trk-type K transport systems, membrane components
NGEPNEPM_00345 4.9e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NGEPNEPM_00346 2.1e-86 yceD K metal-binding, possibly nucleic acid-binding protein
NGEPNEPM_00347 1.1e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NGEPNEPM_00348 6.1e-277 T PhoQ Sensor
NGEPNEPM_00349 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NGEPNEPM_00350 8.2e-213 dnaB L Replication initiation and membrane attachment
NGEPNEPM_00351 1.4e-164 dnaI L Primosomal protein DnaI
NGEPNEPM_00352 6.9e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NGEPNEPM_00353 8.6e-28
NGEPNEPM_00354 7.9e-224 L Transposase
NGEPNEPM_00355 1.1e-226 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NGEPNEPM_00356 6.5e-63 manO S protein conserved in bacteria
NGEPNEPM_00357 1.6e-163 manN G PTS system mannose fructose sorbose family IID component
NGEPNEPM_00358 1.4e-107 manM G pts system
NGEPNEPM_00359 6.6e-171 manL 2.7.1.191 G pts system
NGEPNEPM_00360 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NGEPNEPM_00361 1.2e-143 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NGEPNEPM_00362 7.8e-242 pbuO S permease
NGEPNEPM_00363 1.8e-226 L Transposase
NGEPNEPM_00364 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NGEPNEPM_00365 2.5e-89 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NGEPNEPM_00366 1.9e-207 brpA K Transcriptional
NGEPNEPM_00367 5.7e-80 rimP S Required for maturation of 30S ribosomal subunits
NGEPNEPM_00368 2.5e-212 nusA K Participates in both transcription termination and antitermination
NGEPNEPM_00369 8.8e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NGEPNEPM_00370 1.4e-41 ylxQ J ribosomal protein
NGEPNEPM_00371 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NGEPNEPM_00372 6.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NGEPNEPM_00373 8.7e-54 yvdD 3.2.2.10 S Belongs to the LOG family
NGEPNEPM_00374 5.5e-223 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NGEPNEPM_00375 8.7e-273 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGEPNEPM_00376 3.6e-280 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NGEPNEPM_00377 1.7e-40 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NGEPNEPM_00378 1.7e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
NGEPNEPM_00379 5.8e-219 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NGEPNEPM_00380 3.1e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NGEPNEPM_00381 1.7e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NGEPNEPM_00382 6.4e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NGEPNEPM_00383 1.4e-72 ylbF S Belongs to the UPF0342 family
NGEPNEPM_00384 3.9e-44 ylbG S UPF0298 protein
NGEPNEPM_00385 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NGEPNEPM_00386 2.1e-144 livH E Belongs to the binding-protein-dependent transport system permease family
NGEPNEPM_00387 1.2e-137 livM E Belongs to the binding-protein-dependent transport system permease family
NGEPNEPM_00388 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NGEPNEPM_00389 1.1e-122 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NGEPNEPM_00390 8.9e-69 acuB S IMP dehydrogenase activity
NGEPNEPM_00391 1.2e-42 acuB S IMP dehydrogenase activity
NGEPNEPM_00392 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NGEPNEPM_00393 1.1e-110 yvyE 3.4.13.9 S YigZ family
NGEPNEPM_00394 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NGEPNEPM_00395 3.2e-121 comFC S Competence protein
NGEPNEPM_00396 2.2e-91 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NGEPNEPM_00404 5.2e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
NGEPNEPM_00405 4.2e-116 S Domain of unknown function (DUF1803)
NGEPNEPM_00406 7.8e-102 ygaC J Belongs to the UPF0374 family
NGEPNEPM_00407 2.6e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
NGEPNEPM_00408 3.1e-256 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGEPNEPM_00409 3.3e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
NGEPNEPM_00410 6.9e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
NGEPNEPM_00411 1.2e-114 S Haloacid dehalogenase-like hydrolase
NGEPNEPM_00412 1.5e-138 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NGEPNEPM_00413 5.8e-71 marR K Transcriptional regulator, MarR family
NGEPNEPM_00414 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGEPNEPM_00415 9.7e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGEPNEPM_00416 3.2e-170 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NGEPNEPM_00417 6.7e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NGEPNEPM_00418 1.1e-125 IQ reductase
NGEPNEPM_00419 5.4e-231 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NGEPNEPM_00420 4.2e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NGEPNEPM_00421 1.6e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NGEPNEPM_00422 6.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NGEPNEPM_00423 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NGEPNEPM_00424 2e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NGEPNEPM_00425 3.4e-93 L Transposase
NGEPNEPM_00426 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NGEPNEPM_00427 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
NGEPNEPM_00428 6.9e-42 S Domain of unknown function (DUF1803)
NGEPNEPM_00429 4.5e-47 S Domain of unknown function (DUF1803)
NGEPNEPM_00430 2.5e-157 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NGEPNEPM_00431 1.5e-170 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NGEPNEPM_00432 4e-162 fhuD P ABC transporter, substratebinding protein
NGEPNEPM_00433 2.7e-135 fhuC 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NGEPNEPM_00434 6.8e-15 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGEPNEPM_00435 4.7e-94 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NGEPNEPM_00436 5.1e-10 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NGEPNEPM_00437 2.8e-58
NGEPNEPM_00438 3.6e-214 XK27_12990 P Belongs to the TelA family
NGEPNEPM_00439 2.2e-40 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NGEPNEPM_00440 1.1e-111 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NGEPNEPM_00441 5.6e-114 fruR K transcriptional
NGEPNEPM_00442 1.3e-162 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NGEPNEPM_00443 0.0 fruA 2.7.1.202 G phosphotransferase system
NGEPNEPM_00444 3.9e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NGEPNEPM_00445 3.9e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NGEPNEPM_00447 5.7e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NGEPNEPM_00448 8.8e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NGEPNEPM_00449 7.9e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NGEPNEPM_00450 2e-252 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NGEPNEPM_00451 6.4e-39 2.3.1.128 K acetyltransferase
NGEPNEPM_00452 1.2e-27 2.3.1.128 K acetyltransferase
NGEPNEPM_00453 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NGEPNEPM_00454 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NGEPNEPM_00455 2.9e-85 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NGEPNEPM_00456 2.9e-63 WQ51_03320 S cog cog4835
NGEPNEPM_00457 1.1e-147 XK27_08360 S EDD domain protein, DegV family
NGEPNEPM_00458 4.8e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NGEPNEPM_00459 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NGEPNEPM_00460 0.0 yfmR S abc transporter atp-binding protein
NGEPNEPM_00461 2.6e-22 U response to pH
NGEPNEPM_00462 5.3e-136 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NGEPNEPM_00463 1.4e-43 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NGEPNEPM_00464 4.2e-253 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NGEPNEPM_00465 5.1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NGEPNEPM_00466 6.1e-76 K DNA-binding transcription factor activity
NGEPNEPM_00467 4e-307 lmrA1 V abc transporter atp-binding protein
NGEPNEPM_00468 0.0 lmrA2 V abc transporter atp-binding protein
NGEPNEPM_00469 4.8e-57 K Acetyltransferase (GNAT) family
NGEPNEPM_00470 1e-26 2.7.6.5 S Region found in RelA / SpoT proteins
NGEPNEPM_00471 2.6e-28 2.7.6.5 S Region found in RelA / SpoT proteins
NGEPNEPM_00472 7.9e-32 T response regulator
NGEPNEPM_00473 2.8e-28 T response regulator
NGEPNEPM_00474 1.9e-123 sptS 2.7.13.3 T Histidine kinase
NGEPNEPM_00475 4.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NGEPNEPM_00476 3.8e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NGEPNEPM_00477 1.1e-158 cvfB S Protein conserved in bacteria
NGEPNEPM_00478 7.4e-35 yozE S Belongs to the UPF0346 family
NGEPNEPM_00479 5.9e-114 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NGEPNEPM_00480 5.7e-41 sip M LysM domain protein
NGEPNEPM_00481 6.8e-190 phoH T phosphate starvation-inducible protein PhoH
NGEPNEPM_00486 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGEPNEPM_00487 1.5e-166 K transcriptional regulator (lysR family)
NGEPNEPM_00488 6.1e-182 coiA 3.6.4.12 S Competence protein
NGEPNEPM_00489 0.0 pepF E oligoendopeptidase F
NGEPNEPM_00490 2.3e-125 yrrM 2.1.1.104 S O-Methyltransferase
NGEPNEPM_00491 3e-159 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NGEPNEPM_00492 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NGEPNEPM_00493 5.6e-22 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NGEPNEPM_00494 2.9e-240 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
NGEPNEPM_00495 2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NGEPNEPM_00496 9.4e-225 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NGEPNEPM_00497 5e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NGEPNEPM_00498 9.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NGEPNEPM_00499 2.2e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NGEPNEPM_00500 1.1e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NGEPNEPM_00501 4.7e-128 yxkH G deacetylase
NGEPNEPM_00502 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NGEPNEPM_00503 6.5e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NGEPNEPM_00504 2.6e-150 rarD S Transporter
NGEPNEPM_00505 2.6e-16 T peptidase
NGEPNEPM_00506 2.6e-13 coiA 3.6.4.12 S Competence protein
NGEPNEPM_00507 4.4e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NGEPNEPM_00508 5.5e-73 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NGEPNEPM_00509 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NGEPNEPM_00510 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGEPNEPM_00511 2.2e-120 atpB C it plays a direct role in the translocation of protons across the membrane
NGEPNEPM_00512 4.4e-75 atpF C ATP synthase F(0) sector subunit b
NGEPNEPM_00513 3.9e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGEPNEPM_00514 1.3e-276 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NGEPNEPM_00515 1.9e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NGEPNEPM_00516 4.4e-261 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NGEPNEPM_00517 1.4e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NGEPNEPM_00518 9.2e-226 ftsW D Belongs to the SEDS family
NGEPNEPM_00521 4.5e-54 repA S Replication initiator protein A (RepA) N-terminus
NGEPNEPM_00522 7.2e-45
NGEPNEPM_00523 1.5e-39 S Transcriptional Coactivator p15 (PC4)
NGEPNEPM_00525 3.9e-104
NGEPNEPM_00527 8.5e-12 S PrgI family protein
NGEPNEPM_00528 0.0 U Psort location Cytoplasmic, score
NGEPNEPM_00529 0.0 M CHAP domain protein
NGEPNEPM_00530 1.1e-104
NGEPNEPM_00532 4.5e-65
NGEPNEPM_00533 1.1e-28 MU outer membrane autotransporter barrel domain protein
NGEPNEPM_00534 7.7e-57
NGEPNEPM_00535 3.2e-304 U An automated process has identified a potential problem with this gene model
NGEPNEPM_00537 1e-267 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGEPNEPM_00538 0.0 L Toprim-like
NGEPNEPM_00540 6.5e-47 S Bacterial mobilisation protein (MobC)
NGEPNEPM_00541 1.2e-246 U Relaxase/Mobilisation nuclease domain
NGEPNEPM_00544 1.8e-72 tnpR L Resolvase, N terminal domain
NGEPNEPM_00546 1.1e-112 D CobQ CobB MinD ParA nucleotide binding domain protein
NGEPNEPM_00548 8.6e-127 S Fic/DOC family
NGEPNEPM_00549 1e-163 S Uncharacterised protein family (UPF0236)
NGEPNEPM_00550 1.1e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NGEPNEPM_00551 3.5e-132 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NGEPNEPM_00552 1.1e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NGEPNEPM_00553 6e-160 holB 2.7.7.7 L dna polymerase iii
NGEPNEPM_00554 4.6e-130 yaaT S stage 0 sporulation protein
NGEPNEPM_00555 9.5e-55 yabA L Involved in initiation control of chromosome replication
NGEPNEPM_00556 5e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NGEPNEPM_00557 2.9e-224 amt P Ammonium Transporter
NGEPNEPM_00558 1.8e-51 glnB K Belongs to the P(II) protein family
NGEPNEPM_00559 6e-104 mur1 NU mannosyl-glycoprotein
NGEPNEPM_00560 8.7e-145 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NGEPNEPM_00561 1.8e-66 nptA P COG1283 Na phosphate symporter
NGEPNEPM_00562 1e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NGEPNEPM_00563 1.4e-29 S membrane
NGEPNEPM_00564 3.6e-72 S membrane
NGEPNEPM_00565 1e-62 S membrane
NGEPNEPM_00566 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NGEPNEPM_00567 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NGEPNEPM_00568 4.5e-39 ynzC S UPF0291 protein
NGEPNEPM_00569 4.5e-250 cycA E permease
NGEPNEPM_00570 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
NGEPNEPM_00571 4.8e-24 pts33BCA G pts system
NGEPNEPM_00572 1.5e-46 pts33BCA G pts system
NGEPNEPM_00573 4.1e-34 pts33BCA G pts system
NGEPNEPM_00574 3.9e-76 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NGEPNEPM_00575 3.9e-53 pts33BCA G pts system
NGEPNEPM_00576 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NGEPNEPM_00581 1.5e-166 fhuR K transcriptional regulator (lysR family)
NGEPNEPM_00582 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NGEPNEPM_00583 9.4e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NGEPNEPM_00584 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NGEPNEPM_00585 4.9e-227 pyrP F uracil Permease
NGEPNEPM_00586 2.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NGEPNEPM_00587 3.5e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NGEPNEPM_00588 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NGEPNEPM_00589 3.1e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
NGEPNEPM_00590 6.9e-18 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGEPNEPM_00591 2.2e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGEPNEPM_00592 6.4e-35 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGEPNEPM_00593 9.1e-32 V permease protein
NGEPNEPM_00594 2.2e-19 V efflux transmembrane transporter activity
NGEPNEPM_00595 5.1e-19 ytrF V efflux transmembrane transporter activity
NGEPNEPM_00596 1.8e-76 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NGEPNEPM_00597 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NGEPNEPM_00598 3.3e-78 L Integrase core domain
NGEPNEPM_00599 1.5e-40 S MucBP domain
NGEPNEPM_00600 1.4e-42 M YSIRK type signal peptide
NGEPNEPM_00601 0.0 M the current gene model (or a revised gene model) may contain a
NGEPNEPM_00603 7.3e-31 XK27_00530 M CHAP domain protein
NGEPNEPM_00604 5.9e-103 abiGI K Transcriptional regulator, AbiEi antitoxin
NGEPNEPM_00605 3.9e-271 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NGEPNEPM_00606 5.3e-27 K DNA-binding transcription factor activity
NGEPNEPM_00607 0.0 mdlB V abc transporter atp-binding protein
NGEPNEPM_00608 0.0 lmrA V abc transporter atp-binding protein
NGEPNEPM_00609 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NGEPNEPM_00610 7.5e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NGEPNEPM_00611 3.4e-196 yceA S Belongs to the UPF0176 family
NGEPNEPM_00612 1.2e-26 XK27_00085 K Transcriptional
NGEPNEPM_00613 3.1e-20
NGEPNEPM_00614 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
NGEPNEPM_00615 4.3e-113 S VIT family
NGEPNEPM_00616 1.4e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NGEPNEPM_00617 4.1e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NGEPNEPM_00618 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NGEPNEPM_00619 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NGEPNEPM_00620 8.8e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NGEPNEPM_00621 2.8e-102 GBS0088 J protein conserved in bacteria
NGEPNEPM_00622 1.1e-134 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NGEPNEPM_00623 4.8e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NGEPNEPM_00624 9.5e-170 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NGEPNEPM_00625 1.7e-190 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NGEPNEPM_00626 2.4e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NGEPNEPM_00627 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NGEPNEPM_00628 8.7e-22
NGEPNEPM_00629 4.5e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NGEPNEPM_00631 3e-29 U protein secretion
NGEPNEPM_00632 2.9e-69 U protein secretion
NGEPNEPM_00633 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NGEPNEPM_00634 3.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NGEPNEPM_00635 2.9e-48 XK27_13030
NGEPNEPM_00636 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NGEPNEPM_00637 2.2e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NGEPNEPM_00638 1.3e-162 S Protein of unknown function (DUF3114)
NGEPNEPM_00639 1.2e-22 S Protein of unknown function (DUF3114)
NGEPNEPM_00640 1e-119 yqfA K protein, Hemolysin III
NGEPNEPM_00641 1.8e-226 L Transposase
NGEPNEPM_00642 2.6e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NGEPNEPM_00643 1.7e-218 mvaS 2.3.3.10 I synthase
NGEPNEPM_00644 1.1e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NGEPNEPM_00645 1.3e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NGEPNEPM_00646 9.7e-22
NGEPNEPM_00647 2.8e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NGEPNEPM_00648 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NGEPNEPM_00649 3.7e-249 mmuP E amino acid
NGEPNEPM_00650 2.2e-176 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NGEPNEPM_00651 1.4e-29 S Domain of unknown function (DUF1912)
NGEPNEPM_00652 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
NGEPNEPM_00653 7.9e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NGEPNEPM_00654 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGEPNEPM_00655 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGEPNEPM_00656 9.1e-200 ilvE 2.6.1.42 E Aminotransferase
NGEPNEPM_00657 8.2e-16 S Protein of unknown function (DUF2969)
NGEPNEPM_00660 1.6e-203 rpsA 1.17.7.4 J ribosomal protein S1
NGEPNEPM_00663 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
NGEPNEPM_00664 8.2e-67 M Pfam SNARE associated Golgi protein
NGEPNEPM_00665 6.4e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
NGEPNEPM_00667 1.5e-36 S oxidoreductase
NGEPNEPM_00668 2.6e-101 S oxidoreductase
NGEPNEPM_00669 2.2e-45 XK27_09445 S Domain of unknown function (DUF1827)
NGEPNEPM_00670 4.1e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NGEPNEPM_00671 0.0 clpE O Belongs to the ClpA ClpB family
NGEPNEPM_00672 8.5e-179 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NGEPNEPM_00673 5.1e-34 ykuJ S protein conserved in bacteria
NGEPNEPM_00675 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NGEPNEPM_00676 1.2e-129 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_00677 1e-76 feoA P FeoA domain protein
NGEPNEPM_00678 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NGEPNEPM_00679 1.5e-07
NGEPNEPM_00680 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NGEPNEPM_00681 6.3e-45 K sequence-specific DNA binding
NGEPNEPM_00682 2.5e-33 yugF I carboxylic ester hydrolase activity
NGEPNEPM_00683 5.2e-24 I Alpha/beta hydrolase family
NGEPNEPM_00684 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGEPNEPM_00685 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NGEPNEPM_00686 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NGEPNEPM_00687 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NGEPNEPM_00688 1.1e-133 licT K antiterminator
NGEPNEPM_00689 1.7e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NGEPNEPM_00690 2.9e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NGEPNEPM_00691 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NGEPNEPM_00692 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NGEPNEPM_00693 7.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NGEPNEPM_00694 8e-219 mdtG EGP Major facilitator Superfamily
NGEPNEPM_00695 2.6e-33 secG U Preprotein translocase subunit SecG
NGEPNEPM_00696 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NGEPNEPM_00697 1.5e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NGEPNEPM_00698 3.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NGEPNEPM_00699 2.4e-62 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NGEPNEPM_00700 3.3e-208 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NGEPNEPM_00701 1.1e-176 ccpA K Catabolite control protein A
NGEPNEPM_00702 1.5e-192 yyaQ S YjbR
NGEPNEPM_00703 4e-44 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NGEPNEPM_00704 1.3e-61 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NGEPNEPM_00705 1.5e-62 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NGEPNEPM_00706 5.8e-74 yueI S Protein of unknown function (DUF1694)
NGEPNEPM_00707 1.4e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NGEPNEPM_00708 1.7e-24 WQ51_00785
NGEPNEPM_00709 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NGEPNEPM_00710 9e-220 ywbD 2.1.1.191 J Methyltransferase
NGEPNEPM_00711 7.3e-121 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NGEPNEPM_00712 6.3e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NGEPNEPM_00713 1.9e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NGEPNEPM_00714 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NGEPNEPM_00715 5.9e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NGEPNEPM_00716 1.8e-51 yheA S Belongs to the UPF0342 family
NGEPNEPM_00717 5.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NGEPNEPM_00718 3.2e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NGEPNEPM_00719 3.8e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NGEPNEPM_00720 1.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
NGEPNEPM_00721 6.6e-249 msrR K Transcriptional regulator
NGEPNEPM_00722 8.5e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
NGEPNEPM_00723 1.7e-201 I acyl-CoA dehydrogenase
NGEPNEPM_00724 7.7e-97 mip S hydroperoxide reductase activity
NGEPNEPM_00725 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGEPNEPM_00726 2.7e-30 K TfoX N-terminal domain
NGEPNEPM_00727 9e-87 J Acetyltransferase (GNAT) domain
NGEPNEPM_00728 9.8e-95
NGEPNEPM_00729 1.5e-37 L transposase activity
NGEPNEPM_00730 2.6e-152 L COG2801 Transposase and inactivated derivatives
NGEPNEPM_00731 3.1e-11
NGEPNEPM_00733 3.5e-59 S Protein of unknown function (DUF1722)
NGEPNEPM_00734 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
NGEPNEPM_00736 3.1e-33
NGEPNEPM_00737 1.7e-26 S CAAX protease self-immunity
NGEPNEPM_00738 7.3e-27 estA E GDSL-like Lipase/Acylhydrolase
NGEPNEPM_00739 2.1e-95
NGEPNEPM_00740 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NGEPNEPM_00741 9.3e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NGEPNEPM_00742 1.7e-19 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NGEPNEPM_00743 6.9e-15 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NGEPNEPM_00744 9e-195 S CRISPR-associated protein Csn2 subfamily St
NGEPNEPM_00745 1.2e-146 ycgQ S TIGR03943 family
NGEPNEPM_00746 1.8e-151 XK27_03015 S permease
NGEPNEPM_00748 0.0 yhgF K Transcriptional accessory protein
NGEPNEPM_00749 1.9e-40 pspC KT PspC domain
NGEPNEPM_00750 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NGEPNEPM_00751 2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NGEPNEPM_00753 1.9e-66 ytxH S General stress protein
NGEPNEPM_00755 9.8e-177 yegQ O Peptidase U32
NGEPNEPM_00756 3.4e-252 yegQ O Peptidase U32
NGEPNEPM_00757 4.5e-233 L Transposase
NGEPNEPM_00758 4.6e-86 bioY S biotin synthase
NGEPNEPM_00760 1.1e-33 XK27_12190 S protein conserved in bacteria
NGEPNEPM_00761 1.9e-234 mntH P H( )-stimulated, divalent metal cation uptake system
NGEPNEPM_00763 1.5e-283 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NGEPNEPM_00764 1.6e-14 M LysM domain
NGEPNEPM_00765 2.5e-44 M LysM domain
NGEPNEPM_00766 7.2e-55 M LysM domain
NGEPNEPM_00768 1.9e-172 S hydrolase
NGEPNEPM_00769 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NGEPNEPM_00770 3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NGEPNEPM_00771 9.7e-148 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NGEPNEPM_00772 1.6e-27 P Hemerythrin HHE cation binding domain protein
NGEPNEPM_00773 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NGEPNEPM_00774 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
NGEPNEPM_00775 1.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
NGEPNEPM_00776 4.8e-129 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NGEPNEPM_00777 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NGEPNEPM_00778 2e-165 S Bacteriophage abortive infection AbiH
NGEPNEPM_00780 1.6e-89 3.1.21.3 V Type I restriction modification DNA specificity domain
NGEPNEPM_00781 8.5e-42 K Helix-turn-helix domain
NGEPNEPM_00782 2.8e-304 hsdM 2.1.1.72 V type I restriction-modification system
NGEPNEPM_00783 5.9e-22 S PD-(D/E)XK nuclease family transposase
NGEPNEPM_00784 2.4e-14 spd F DNA RNA non-specific endonuclease
NGEPNEPM_00785 2e-42 spd F DNA RNA non-specific endonuclease
NGEPNEPM_00786 3e-69 spd F DNA RNA non-specific endonuclease
NGEPNEPM_00787 5e-91 lemA S LemA family
NGEPNEPM_00788 2.1e-131 htpX O Belongs to the peptidase M48B family
NGEPNEPM_00789 1.2e-74 S Psort location CytoplasmicMembrane, score
NGEPNEPM_00790 1.8e-55 S Domain of unknown function (DUF4430)
NGEPNEPM_00791 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NGEPNEPM_00792 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
NGEPNEPM_00793 1.8e-110 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NGEPNEPM_00794 9.5e-178 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NGEPNEPM_00795 5.7e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NGEPNEPM_00796 1.8e-90 dps P Belongs to the Dps family
NGEPNEPM_00797 8.9e-80 perR P Belongs to the Fur family
NGEPNEPM_00798 1.9e-27 yqgQ S protein conserved in bacteria
NGEPNEPM_00799 1.2e-177 glk 2.7.1.2 G Glucokinase
NGEPNEPM_00800 0.0 typA T GTP-binding protein TypA
NGEPNEPM_00802 1.6e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NGEPNEPM_00803 1.9e-195 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NGEPNEPM_00804 2.6e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NGEPNEPM_00805 2.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NGEPNEPM_00806 2.5e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NGEPNEPM_00807 3.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NGEPNEPM_00808 7e-93 sepF D cell septum assembly
NGEPNEPM_00809 5.7e-34 yggT D integral membrane protein
NGEPNEPM_00810 8.2e-140 ylmH T S4 RNA-binding domain
NGEPNEPM_00811 3.8e-130 divIVA D Cell division protein DivIVA
NGEPNEPM_00812 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NGEPNEPM_00813 1.2e-63 L the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_00814 1e-216 mntH P Mn2 and Fe2 transporters of the NRAMP family
NGEPNEPM_00815 2.4e-43 rpmE2 J 50S ribosomal protein L31
NGEPNEPM_00816 2.3e-170 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NGEPNEPM_00817 4.9e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NGEPNEPM_00818 8.9e-155 gst O Glutathione S-transferase
NGEPNEPM_00819 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NGEPNEPM_00820 2.4e-112 tdk 2.7.1.21 F thymidine kinase
NGEPNEPM_00821 3.3e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NGEPNEPM_00822 1e-148 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NGEPNEPM_00823 1.1e-107 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NGEPNEPM_00824 4.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NGEPNEPM_00825 1.3e-174 ndpA S 37-kD nucleoid-associated bacterial protein
NGEPNEPM_00826 5e-105 pvaA M lytic transglycosylase activity
NGEPNEPM_00827 6.5e-307 yfiB1 V abc transporter atp-binding protein
NGEPNEPM_00828 0.0 XK27_10035 V abc transporter atp-binding protein
NGEPNEPM_00829 1.3e-09 S D-Ala-teichoic acid biosynthesis protein
NGEPNEPM_00830 8.7e-295 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGEPNEPM_00831 1.9e-231 dltB M Membrane protein involved in D-alanine export
NGEPNEPM_00832 1.8e-34 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGEPNEPM_00833 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NGEPNEPM_00834 2.8e-19 L Integrase core domain protein
NGEPNEPM_00835 6e-46 L transposase activity
NGEPNEPM_00836 0.0 3.6.3.8 P cation transport ATPase
NGEPNEPM_00837 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NGEPNEPM_00839 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NGEPNEPM_00840 3.1e-164 metF 1.5.1.20 C reductase
NGEPNEPM_00841 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NGEPNEPM_00842 9.2e-93 panT S ECF transporter, substrate-specific component
NGEPNEPM_00843 3.7e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NGEPNEPM_00844 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NGEPNEPM_00845 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NGEPNEPM_00846 3e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NGEPNEPM_00847 1.2e-97 T PhoQ Sensor
NGEPNEPM_00848 2.4e-84 T PhoQ Sensor
NGEPNEPM_00849 2.3e-29 rpsT J rRNA binding
NGEPNEPM_00850 3.6e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NGEPNEPM_00851 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
NGEPNEPM_00852 2.1e-14 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NGEPNEPM_00853 2e-34 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NGEPNEPM_00854 2.1e-32 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NGEPNEPM_00855 1.1e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
NGEPNEPM_00856 1.1e-80 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NGEPNEPM_00857 2.3e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NGEPNEPM_00858 1.2e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NGEPNEPM_00859 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NGEPNEPM_00860 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
NGEPNEPM_00861 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NGEPNEPM_00862 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NGEPNEPM_00863 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NGEPNEPM_00864 2e-80 ypmB S Protein conserved in bacteria
NGEPNEPM_00865 1e-215 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NGEPNEPM_00866 1.2e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NGEPNEPM_00867 1.7e-16
NGEPNEPM_00868 6.8e-54 L Transposase
NGEPNEPM_00869 3.9e-30
NGEPNEPM_00870 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NGEPNEPM_00871 1.3e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NGEPNEPM_00872 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NGEPNEPM_00873 8.8e-113 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NGEPNEPM_00874 2.7e-93 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NGEPNEPM_00875 6.5e-19 D nuclear chromosome segregation
NGEPNEPM_00876 2.2e-134 yejC S cyclic nucleotide-binding protein
NGEPNEPM_00877 4.5e-163 rapZ S Displays ATPase and GTPase activities
NGEPNEPM_00878 3.4e-180 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NGEPNEPM_00879 5.7e-161 whiA K May be required for sporulation
NGEPNEPM_00880 4.7e-80 pepD E Dipeptidase
NGEPNEPM_00881 2.6e-44 pepD E Dipeptidase
NGEPNEPM_00882 1.5e-75 tspO T TspO/MBR family
NGEPNEPM_00883 2e-59 S Uncharacterised lipoprotein family
NGEPNEPM_00884 3e-96 L transposase IS3 IS911 family protein
NGEPNEPM_00885 1.3e-156 L EVIDENCE EXPERIMENTAL PMID 1328163 BIO14.04 Transposon related functions. BELONGS TO THE IS3 IS150 IS904 FAMILY OF TRANSPOSASE. There are 7 such elements in the chromosome
NGEPNEPM_00886 5.4e-189 L Transposase
NGEPNEPM_00887 7.1e-28 L transposase activity
NGEPNEPM_00889 9e-27
NGEPNEPM_00890 2.3e-30 cspD K Cold shock protein domain
NGEPNEPM_00891 1.7e-232 L Transposase
NGEPNEPM_00892 2.3e-41 K Cold-Shock Protein
NGEPNEPM_00893 1.3e-221 L Transposase
NGEPNEPM_00894 4.4e-112 hsdM 2.1.1.72 V type I restriction-modification system
NGEPNEPM_00895 1.3e-15 glcU U sugar transport
NGEPNEPM_00896 1.4e-234 L Transposase
NGEPNEPM_00897 7.7e-122 glcU U sugar transport
NGEPNEPM_00898 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
NGEPNEPM_00899 4.5e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
NGEPNEPM_00900 3.1e-69 XK27_10720 D peptidase activity
NGEPNEPM_00901 7.8e-280 adcA P Belongs to the bacterial solute-binding protein 9 family
NGEPNEPM_00902 3.7e-08
NGEPNEPM_00903 1.8e-171 yeiH S Membrane
NGEPNEPM_00904 2.6e-97 mur1 NU muramidase
NGEPNEPM_00905 1.6e-29 L transposase activity
NGEPNEPM_00906 9.9e-166 cpsY K Transcriptional regulator
NGEPNEPM_00907 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NGEPNEPM_00908 6.8e-56 phnA P Alkylphosphonate utilization operon protein PhnA
NGEPNEPM_00909 9.7e-28 artQ P ABC transporter (Permease
NGEPNEPM_00910 3.1e-105 artQ P ABC transporter (Permease
NGEPNEPM_00911 2e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_00912 4.6e-157 aatB ET ABC transporter substrate-binding protein
NGEPNEPM_00913 5e-67 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_00914 1.9e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_00915 9.2e-26
NGEPNEPM_00916 8.4e-17 adhP 1.1.1.1 C alcohol dehydrogenase
NGEPNEPM_00917 8.5e-79 adhP 1.1.1.1 C alcohol dehydrogenase
NGEPNEPM_00919 5.1e-21
NGEPNEPM_00920 0.0 res_1 3.1.21.5 S Type III restriction
NGEPNEPM_00921 6e-136 sthIM 2.1.1.72 L DNA methylase
NGEPNEPM_00922 1.4e-234 L Transposase
NGEPNEPM_00923 2.5e-84 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NGEPNEPM_00924 1.8e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NGEPNEPM_00925 3.5e-126 gntR1 K transcriptional
NGEPNEPM_00926 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NGEPNEPM_00927 6.7e-271 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NGEPNEPM_00928 2.9e-85 niaX
NGEPNEPM_00929 2.8e-88 niaR S small molecule binding protein (contains 3H domain)
NGEPNEPM_00930 8.1e-128 K DNA-binding helix-turn-helix protein
NGEPNEPM_00931 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NGEPNEPM_00932 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGEPNEPM_00933 3.5e-166 GK ROK family
NGEPNEPM_00934 3.5e-157 dprA LU DNA protecting protein DprA
NGEPNEPM_00935 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGEPNEPM_00936 1.5e-152 S TraX protein
NGEPNEPM_00937 1.9e-121 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NGEPNEPM_00938 2.8e-244 T PhoQ Sensor
NGEPNEPM_00939 1.2e-255 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NGEPNEPM_00940 1.4e-217 XK27_05470 E Methionine synthase
NGEPNEPM_00941 6.5e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NGEPNEPM_00942 1.9e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NGEPNEPM_00943 1.3e-19 IQ Acetoin reductase
NGEPNEPM_00944 5.3e-59 IQ Acetoin reductase
NGEPNEPM_00945 3.9e-19 IQ Acetoin reductase
NGEPNEPM_00947 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NGEPNEPM_00949 6.7e-90 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NGEPNEPM_00950 2.9e-218 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NGEPNEPM_00951 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NGEPNEPM_00952 1.1e-231 L Transposase
NGEPNEPM_00953 8.2e-118 V ABC transporter (Permease
NGEPNEPM_00954 8.4e-112 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NGEPNEPM_00955 6.2e-10
NGEPNEPM_00956 2.2e-96 K Transcriptional regulator, TetR family
NGEPNEPM_00957 3.1e-159 czcD P cation diffusion facilitator family transporter
NGEPNEPM_00958 2e-109 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NGEPNEPM_00959 4.2e-43 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NGEPNEPM_00960 1.5e-194 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NGEPNEPM_00961 6e-08 S Hydrolases of the alpha beta superfamily
NGEPNEPM_00962 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
NGEPNEPM_00963 2.5e-30 S Alpha/beta hydrolase of unknown function (DUF915)
NGEPNEPM_00966 2.6e-143 2.4.2.3 F Phosphorylase superfamily
NGEPNEPM_00967 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NGEPNEPM_00968 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
NGEPNEPM_00969 8.7e-73 dinF V Mate efflux family protein
NGEPNEPM_00970 6.3e-12 dinF V Mate efflux family protein
NGEPNEPM_00971 3.9e-26 dinF V drug transmembrane transporter activity
NGEPNEPM_00972 3.9e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NGEPNEPM_00974 8.3e-86 S TraX protein
NGEPNEPM_00975 8.5e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NGEPNEPM_00976 9.1e-176 L Transposase
NGEPNEPM_00977 4.8e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NGEPNEPM_00978 5e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NGEPNEPM_00979 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NGEPNEPM_00980 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NGEPNEPM_00981 3.1e-69 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NGEPNEPM_00982 3.2e-216 mesE M HlyD family secretion protein
NGEPNEPM_00983 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGEPNEPM_00987 2.6e-46 S Enterocin A Immunity
NGEPNEPM_00988 3.1e-10 blpU S hmm tigr01847
NGEPNEPM_00992 7.4e-09 S Bacteriocin class II with double-glycine leader peptide
NGEPNEPM_00993 6e-54
NGEPNEPM_00995 4.9e-16
NGEPNEPM_00996 2.4e-103 blpT
NGEPNEPM_00997 5.8e-26
NGEPNEPM_00998 1.2e-132 agrA KT phosphorelay signal transduction system
NGEPNEPM_00999 2e-138 2.7.13.3 T protein histidine kinase activity
NGEPNEPM_01001 1.8e-51 csm6 S Psort location Cytoplasmic, score
NGEPNEPM_01002 7.8e-117 csm6 S Psort location Cytoplasmic, score
NGEPNEPM_01003 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NGEPNEPM_01004 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NGEPNEPM_01006 2.3e-153 nylA 3.5.1.4 J Belongs to the amidase family
NGEPNEPM_01007 2.7e-40 yckB ET Belongs to the bacterial solute-binding protein 3 family
NGEPNEPM_01008 1.1e-66 yecS P ABC transporter (Permease
NGEPNEPM_01009 3.5e-21 yecS P amino acid transport
NGEPNEPM_01011 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NGEPNEPM_01012 1.7e-18 yfiF3 K sequence-specific DNA binding
NGEPNEPM_01013 1e-22 bglC K Transcriptional regulator
NGEPNEPM_01014 6.1e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NGEPNEPM_01015 4.9e-238 agcS E (Alanine) symporter
NGEPNEPM_01016 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NGEPNEPM_01017 7e-234 metY 2.5.1.49 E o-acetylhomoserine
NGEPNEPM_01018 4.3e-51 S haloacid dehalogenase-like hydrolase
NGEPNEPM_01019 1e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NGEPNEPM_01020 1.3e-108 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NGEPNEPM_01021 9.8e-33 M1-755 P Hemerythrin HHE cation binding domain protein
NGEPNEPM_01022 3.2e-229 XK27_04775 S hemerythrin HHE cation binding domain
NGEPNEPM_01023 1.1e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NGEPNEPM_01024 1e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NGEPNEPM_01025 3.1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NGEPNEPM_01026 2.1e-42 yktA S Belongs to the UPF0223 family
NGEPNEPM_01027 6.7e-131 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NGEPNEPM_01028 1.8e-248 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NGEPNEPM_01029 9.9e-155 pstS P phosphate
NGEPNEPM_01030 2.1e-155 pstC P probably responsible for the translocation of the substrate across the membrane
NGEPNEPM_01031 4.5e-155 pstA P phosphate transport system permease
NGEPNEPM_01032 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NGEPNEPM_01033 8.6e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NGEPNEPM_01034 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
NGEPNEPM_01035 0.0 pepN 3.4.11.2 E aminopeptidase
NGEPNEPM_01036 4.7e-191 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NGEPNEPM_01037 2e-183 lplA 6.3.1.20 H Lipoate-protein ligase
NGEPNEPM_01038 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NGEPNEPM_01039 1.4e-270 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NGEPNEPM_01040 1.4e-125 malR K Transcriptional regulator
NGEPNEPM_01041 1.8e-119 malX G ABC transporter
NGEPNEPM_01042 3.3e-66 malF P ABC transporter (Permease
NGEPNEPM_01043 7.9e-83 malF P ABC transporter (Permease
NGEPNEPM_01044 1.1e-127 malG P ABC transporter (Permease
NGEPNEPM_01045 5e-58 msmX P Belongs to the ABC transporter superfamily
NGEPNEPM_01046 3.1e-234 L Transposase
NGEPNEPM_01047 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
NGEPNEPM_01048 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
NGEPNEPM_01049 2.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NGEPNEPM_01050 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NGEPNEPM_01051 4.4e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NGEPNEPM_01052 2.6e-86 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NGEPNEPM_01053 2.3e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NGEPNEPM_01054 5.2e-210 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NGEPNEPM_01055 2.2e-135 3.5.1.28 NU amidase activity
NGEPNEPM_01056 2.9e-29 3.5.1.28 NU amidase activity
NGEPNEPM_01057 1.3e-56 3.5.1.28 NU amidase activity
NGEPNEPM_01058 5.3e-69 3.5.1.28 NU amidase activity
NGEPNEPM_01059 0.0 lpdA 1.8.1.4 C Dehydrogenase
NGEPNEPM_01060 1.1e-197 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NGEPNEPM_01061 1.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NGEPNEPM_01062 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NGEPNEPM_01063 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01064 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NGEPNEPM_01065 2.5e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NGEPNEPM_01066 1.2e-214 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NGEPNEPM_01067 1.9e-158 rssA S Phospholipase, patatin family
NGEPNEPM_01068 4.8e-76 estA E Lysophospholipase L1 and related esterases
NGEPNEPM_01069 3.5e-291 S unusual protein kinase
NGEPNEPM_01070 4.9e-39 S granule-associated protein
NGEPNEPM_01071 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGEPNEPM_01072 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
NGEPNEPM_01073 4.5e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGEPNEPM_01074 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
NGEPNEPM_01075 1e-199 S hmm pf01594
NGEPNEPM_01076 3.1e-84 G Belongs to the phosphoglycerate mutase family
NGEPNEPM_01077 1.2e-87 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NGEPNEPM_01078 5.8e-95 V VanZ like family
NGEPNEPM_01079 3.9e-99 L Transposase
NGEPNEPM_01080 1.3e-111 L Transposase
NGEPNEPM_01081 3.8e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
NGEPNEPM_01082 2.7e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NGEPNEPM_01083 2.2e-183 cps1C S Polysaccharide biosynthesis protein
NGEPNEPM_01084 7.3e-44 cps1C S Polysaccharide biosynthesis protein
NGEPNEPM_01085 5.8e-141 cps1B GT2,GT4 M Glycosyl transferases group 1
NGEPNEPM_01086 2.4e-61 S the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01087 1.1e-137 S the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01088 7.5e-90 3.6.4.12 L UvrD/REP helicase N-terminal domain
NGEPNEPM_01089 3.6e-101 S Polysaccharide biosynthesis protein
NGEPNEPM_01090 8.6e-16 M O-Antigen ligase
NGEPNEPM_01091 3.2e-24 S Psort location Cytoplasmic, score 9.26
NGEPNEPM_01092 4.6e-59 epsJ GT2 V Glycosyl transferase, family 2
NGEPNEPM_01093 1.3e-154 S Glycosyltransferase WbsX
NGEPNEPM_01094 9.7e-95 MA20_43635 M Capsular polysaccharide synthesis protein
NGEPNEPM_01095 9.4e-123 licD M LicD family
NGEPNEPM_01096 2.8e-173 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NGEPNEPM_01097 4.1e-204 rgpAc GT4 M Domain of unknown function (DUF1972)
NGEPNEPM_01098 1.5e-86 cpsE M Bacterial sugar transferase
NGEPNEPM_01099 2.1e-86 cpsE M Bacterial sugar transferase
NGEPNEPM_01100 3.7e-23 rgpAc GT4 M group 1 family protein
NGEPNEPM_01101 1.3e-179 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NGEPNEPM_01102 1.2e-180 L Transposase
NGEPNEPM_01103 4.8e-38 L Transposase
NGEPNEPM_01104 5.9e-20 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NGEPNEPM_01105 3.4e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
NGEPNEPM_01106 3e-98 cps4C M biosynthesis protein
NGEPNEPM_01107 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NGEPNEPM_01108 5e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NGEPNEPM_01109 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NGEPNEPM_01110 3.7e-117 yfeJ 6.3.5.2 F glutamine amidotransferase
NGEPNEPM_01111 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NGEPNEPM_01112 3.1e-40 S Protein of unknown function (DUF1697)
NGEPNEPM_01113 6e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NGEPNEPM_01114 5.2e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NGEPNEPM_01115 1.6e-07 V Glucan-binding protein C
NGEPNEPM_01116 6.1e-22 V Glucan-binding protein C
NGEPNEPM_01117 4.8e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
NGEPNEPM_01118 1.2e-271 pepV 3.5.1.18 E Dipeptidase
NGEPNEPM_01119 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NGEPNEPM_01120 1.2e-70 XK27_03610 K Gnat family
NGEPNEPM_01121 4.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NGEPNEPM_01122 1.2e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NGEPNEPM_01123 7.8e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NGEPNEPM_01124 8.9e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NGEPNEPM_01125 8.1e-18 M LysM domain
NGEPNEPM_01126 5.1e-87 ebsA S Family of unknown function (DUF5322)
NGEPNEPM_01127 2.3e-226 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NGEPNEPM_01128 1.3e-94 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NGEPNEPM_01129 4.5e-222 G COG0457 FOG TPR repeat
NGEPNEPM_01130 4.4e-174 yubA S permease
NGEPNEPM_01131 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NGEPNEPM_01132 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NGEPNEPM_01133 3.6e-123 ftsE D cell division ATP-binding protein FtsE
NGEPNEPM_01134 1.4e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NGEPNEPM_01135 2.5e-200 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NGEPNEPM_01136 1.3e-181 yjjH S Calcineurin-like phosphoesterase
NGEPNEPM_01137 2e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NGEPNEPM_01138 0.0 pacL 3.6.3.8 P cation transport ATPase
NGEPNEPM_01139 2.6e-67 ywiB S Domain of unknown function (DUF1934)
NGEPNEPM_01140 8.3e-69 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
NGEPNEPM_01141 2.9e-16 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
NGEPNEPM_01142 2e-146 yidA S hydrolases of the HAD superfamily
NGEPNEPM_01143 6.5e-229 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NGEPNEPM_01144 3.2e-34 F Protein of unknown function (DUF454)
NGEPNEPM_01145 8.1e-151 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NGEPNEPM_01146 1.9e-245 vicK 2.7.13.3 T Histidine kinase
NGEPNEPM_01147 1.2e-126 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NGEPNEPM_01148 2.8e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_01149 5.6e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NGEPNEPM_01150 4.4e-113 gltJ P ABC transporter (Permease
NGEPNEPM_01151 1.5e-107 tcyB_2 P ABC transporter (permease)
NGEPNEPM_01152 1.6e-230 L Transposase
NGEPNEPM_01153 2e-23 L Transposase for ISSha1
NGEPNEPM_01154 2.4e-47 U response to pH
NGEPNEPM_01155 1.5e-175 L Transposase
NGEPNEPM_01156 1.4e-145 endA F DNA RNA non-specific endonuclease
NGEPNEPM_01157 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NGEPNEPM_01158 1.3e-227 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGEPNEPM_01160 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NGEPNEPM_01161 3.1e-27 G Domain of unknown function (DUF4832)
NGEPNEPM_01162 6e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NGEPNEPM_01163 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NGEPNEPM_01164 1.5e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGEPNEPM_01165 2.6e-86 ytsP 1.8.4.14 T GAF domain-containing protein
NGEPNEPM_01166 5.6e-161 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NGEPNEPM_01167 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NGEPNEPM_01170 4.7e-39 ps115 K Helix-turn-helix XRE-family like proteins
NGEPNEPM_01171 1.3e-32
NGEPNEPM_01172 6.1e-21 E Zn peptidase
NGEPNEPM_01173 7.6e-61 S CD20-like family
NGEPNEPM_01174 5e-115 S Phage integrase family
NGEPNEPM_01175 2.5e-49 L Transposase
NGEPNEPM_01176 5.4e-161 L Transposase
NGEPNEPM_01178 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NGEPNEPM_01179 3.7e-216 XK27_05110 P chloride
NGEPNEPM_01180 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NGEPNEPM_01181 1.9e-281 clcA P Chloride transporter, ClC family
NGEPNEPM_01182 1e-75 fld C Flavodoxin
NGEPNEPM_01183 3.6e-13 XK27_08880
NGEPNEPM_01184 2e-124 XK27_08875 O Zinc-dependent metalloprotease
NGEPNEPM_01185 4.6e-151 estA CE1 S Putative esterase
NGEPNEPM_01186 1.5e-305 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGEPNEPM_01187 4.2e-133 XK27_08845 S abc transporter atp-binding protein
NGEPNEPM_01188 1.7e-143 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NGEPNEPM_01189 5.8e-175 XK27_08835 S ABC transporter substrate binding protein
NGEPNEPM_01190 3.2e-17 S Domain of unknown function (DUF4649)
NGEPNEPM_01191 9e-11 Q the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01192 4.6e-13 Q the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01193 8.3e-10 Q the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_01194 1.9e-275 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NGEPNEPM_01195 6.3e-185 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NGEPNEPM_01196 0.0 dnaE 2.7.7.7 L DNA polymerase
NGEPNEPM_01197 6.2e-148 sua5 2.7.7.87 J Belongs to the SUA5 family
NGEPNEPM_01198 1.2e-111 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NGEPNEPM_01199 4.3e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NGEPNEPM_01200 4.4e-186 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NGEPNEPM_01201 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NGEPNEPM_01202 1.3e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGEPNEPM_01203 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NGEPNEPM_01206 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NGEPNEPM_01207 3e-91 ypmS S Protein conserved in bacteria
NGEPNEPM_01208 5.7e-142 ypmR E lipolytic protein G-D-S-L family
NGEPNEPM_01209 1.8e-145 DegV S DegV family
NGEPNEPM_01210 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
NGEPNEPM_01211 1.4e-72 argR K arginine binding
NGEPNEPM_01212 1.2e-152 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NGEPNEPM_01213 2.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NGEPNEPM_01214 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NGEPNEPM_01215 1e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NGEPNEPM_01217 1e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NGEPNEPM_01218 1.2e-123 dnaD
NGEPNEPM_01219 3.7e-179 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NGEPNEPM_01220 1.9e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NGEPNEPM_01221 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NGEPNEPM_01222 3.4e-39 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NGEPNEPM_01223 7.9e-64 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NGEPNEPM_01224 1.3e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NGEPNEPM_01225 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NGEPNEPM_01226 9.2e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NGEPNEPM_01227 1.4e-230 rodA D Belongs to the SEDS family
NGEPNEPM_01228 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NGEPNEPM_01229 2.1e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NGEPNEPM_01230 6.8e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NGEPNEPM_01231 9.4e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NGEPNEPM_01232 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NGEPNEPM_01233 1.8e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NGEPNEPM_01234 3.5e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NGEPNEPM_01235 8.8e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NGEPNEPM_01236 2.1e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NGEPNEPM_01237 3.4e-194 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NGEPNEPM_01238 4.1e-33 L Integrase core domain protein
NGEPNEPM_01239 7.5e-47 L transposition
NGEPNEPM_01240 1.7e-28 L Transposase
NGEPNEPM_01241 1.1e-52 XK27_08085
NGEPNEPM_01242 2.3e-52 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NGEPNEPM_01243 8.7e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NGEPNEPM_01244 3.2e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NGEPNEPM_01245 1e-119 ylfI S tigr01906
NGEPNEPM_01246 7.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NGEPNEPM_01247 8.5e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
NGEPNEPM_01248 2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NGEPNEPM_01252 4.8e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NGEPNEPM_01253 2.4e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NGEPNEPM_01254 6e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NGEPNEPM_01255 9e-206 yurR 1.4.5.1 E oxidoreductase
NGEPNEPM_01256 2e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
NGEPNEPM_01257 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
NGEPNEPM_01258 1.4e-147 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NGEPNEPM_01259 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NGEPNEPM_01260 1.3e-70 gtrA S GtrA-like protein
NGEPNEPM_01261 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NGEPNEPM_01262 1.5e-164 ybbR S Protein conserved in bacteria
NGEPNEPM_01263 1.7e-120 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NGEPNEPM_01264 4.9e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NGEPNEPM_01265 8.7e-150 cobQ S glutamine amidotransferase
NGEPNEPM_01266 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NGEPNEPM_01267 1.8e-125 pip 1.11.1.10 S Alpha beta hydrolase
NGEPNEPM_01269 0.0 uup S abc transporter atp-binding protein
NGEPNEPM_01270 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NGEPNEPM_01271 9.7e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
NGEPNEPM_01272 7.1e-24 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NGEPNEPM_01273 1.3e-108 XK27_05680 6.3.2.4 M carbamoylphosphate synthase large subunit
NGEPNEPM_01274 2.5e-50 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
NGEPNEPM_01275 4.8e-42 XK27_05675 S Esterase
NGEPNEPM_01276 6.1e-36 XK27_05675 S Esterase
NGEPNEPM_01277 2.6e-32 XK27_05670 S Putative esterase
NGEPNEPM_01278 7.3e-27 XK27_05670 S Putative esterase
NGEPNEPM_01279 6.8e-262 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NGEPNEPM_01280 1.4e-234 L Transposase
NGEPNEPM_01281 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NGEPNEPM_01282 1.5e-37 ptsH G phosphocarrier protein Hpr
NGEPNEPM_01283 3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
NGEPNEPM_01284 1.9e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
NGEPNEPM_01285 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NGEPNEPM_01286 8.5e-34 nrdH O Glutaredoxin
NGEPNEPM_01287 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGEPNEPM_01288 1.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGEPNEPM_01290 3.7e-59 L PFAM transposase IS116 IS110 IS902 family
NGEPNEPM_01291 9e-24 L Transposase (IS116 IS110 IS902 family)
NGEPNEPM_01292 4.2e-162 ypuA S secreted protein
NGEPNEPM_01293 3.4e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NGEPNEPM_01294 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NGEPNEPM_01295 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGEPNEPM_01296 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NGEPNEPM_01297 8.3e-257 noxE P NADH oxidase
NGEPNEPM_01298 1.8e-292 yfmM S abc transporter atp-binding protein
NGEPNEPM_01299 3.7e-59 XK27_01265 S ECF-type riboflavin transporter, S component
NGEPNEPM_01300 1.5e-11 XK27_01265 S ECF-type riboflavin transporter, S component
NGEPNEPM_01301 1.2e-139 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NGEPNEPM_01302 9.7e-86 S ECF-type riboflavin transporter, S component
NGEPNEPM_01304 8.5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NGEPNEPM_01305 3.5e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NGEPNEPM_01308 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGEPNEPM_01309 3.8e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NGEPNEPM_01310 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NGEPNEPM_01311 0.0 smc D Required for chromosome condensation and partitioning
NGEPNEPM_01312 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NGEPNEPM_01313 2.8e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NGEPNEPM_01314 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NGEPNEPM_01315 1.7e-78 alkD L Dna alkylation repair
NGEPNEPM_01316 9.1e-92 pat 2.3.1.183 M acetyltransferase
NGEPNEPM_01317 2.5e-12
NGEPNEPM_01318 6.1e-50
NGEPNEPM_01319 1.6e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGEPNEPM_01320 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NGEPNEPM_01321 4.6e-38 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NGEPNEPM_01322 1.1e-21 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NGEPNEPM_01323 1.3e-120 sdaAB 4.3.1.17 E L-serine dehydratase
NGEPNEPM_01324 3.4e-29 sdaAA 4.3.1.17 E L-serine dehydratase
NGEPNEPM_01325 5.3e-102 sdaAA 4.3.1.17 E L-serine dehydratase
NGEPNEPM_01326 9.1e-40 S ABC-2 family transporter protein
NGEPNEPM_01327 1.4e-82 S ABC-2 family transporter protein
NGEPNEPM_01328 7.3e-98 S transport system, permease component
NGEPNEPM_01329 2.4e-99 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NGEPNEPM_01330 3.7e-191 desK 2.7.13.3 T Histidine kinase
NGEPNEPM_01331 1.5e-132 yvfS V ABC-2 type transporter
NGEPNEPM_01332 2.4e-156 XK27_09825 V abc transporter atp-binding protein
NGEPNEPM_01335 2.8e-163 yocS S Transporter
NGEPNEPM_01336 6.8e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NGEPNEPM_01337 5e-35 XK27_05000 S metal cluster binding
NGEPNEPM_01338 0.0 V ABC transporter (permease)
NGEPNEPM_01339 8.4e-134 macB2 V ABC transporter, ATP-binding protein
NGEPNEPM_01340 7.6e-164 T Histidine kinase
NGEPNEPM_01341 9.2e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NGEPNEPM_01342 1e-76 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NGEPNEPM_01343 1.4e-132 pbuX F xanthine permease
NGEPNEPM_01344 8.6e-44 pbuX F xanthine permease
NGEPNEPM_01345 2.9e-246 norM V Multidrug efflux pump
NGEPNEPM_01346 3.1e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NGEPNEPM_01347 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
NGEPNEPM_01348 1.1e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
NGEPNEPM_01349 7.7e-55 manA 5.3.1.8 G mannose-6-phosphate isomerase
NGEPNEPM_01350 2.1e-25 csbD K CsbD-like
NGEPNEPM_01351 3.1e-227 yfnA E amino acid
NGEPNEPM_01352 6.3e-108 XK27_02070 S nitroreductase
NGEPNEPM_01353 5.9e-20 1.13.11.2 S glyoxalase
NGEPNEPM_01354 8.8e-93 1.13.11.2 S glyoxalase
NGEPNEPM_01355 2.3e-75 ywnA K Transcriptional regulator
NGEPNEPM_01356 2.8e-157 E Alpha/beta hydrolase of unknown function (DUF915)
NGEPNEPM_01357 2.2e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NGEPNEPM_01358 8.3e-111 drgA C Nitroreductase
NGEPNEPM_01359 3.3e-85 yoaK S Protein of unknown function (DUF1275)
NGEPNEPM_01361 6.8e-161 yvgN C reductase
NGEPNEPM_01362 4.5e-177 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NGEPNEPM_01363 9.8e-280 XK27_07020 S Belongs to the UPF0371 family
NGEPNEPM_01365 1.1e-37 BP1961 P nitric oxide dioxygenase activity
NGEPNEPM_01366 2.7e-53 K response regulator
NGEPNEPM_01367 3.5e-71 S Signal peptide protein, YSIRK family
NGEPNEPM_01368 1.4e-59
NGEPNEPM_01369 1.3e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_01370 5.9e-118
NGEPNEPM_01371 1.7e-16
NGEPNEPM_01372 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NGEPNEPM_01373 6.1e-94 3.1.21.3 V Type I restriction modification DNA specificity domain
NGEPNEPM_01374 1e-308 hsdM 2.1.1.72 V Type I restriction-modification system
NGEPNEPM_01375 0.0 M family 8
NGEPNEPM_01376 2.8e-164 hrtB V MacB-like periplasmic core domain
NGEPNEPM_01377 1.7e-117 devA 3.6.3.25 V abc transporter atp-binding protein
NGEPNEPM_01378 7.9e-18 L Integrase core domain
NGEPNEPM_01379 2.2e-51
NGEPNEPM_01380 9.4e-45
NGEPNEPM_01381 2.3e-109 L Transposase
NGEPNEPM_01382 8.2e-89 L overlaps another CDS with the same product name
NGEPNEPM_01383 1.7e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
NGEPNEPM_01384 6.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NGEPNEPM_01385 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
NGEPNEPM_01386 9e-127 S metal-dependent hydrolase with the TIM-barrel fold
NGEPNEPM_01387 7.7e-123 dlpA H Methyltransferase
NGEPNEPM_01388 9e-50 dlpA 1.1.1.85 CE Tartrate dehydrogenase
NGEPNEPM_01389 7.8e-40 L Transposase
NGEPNEPM_01390 1e-153 L Integrase core domain protein
NGEPNEPM_01391 1e-31
NGEPNEPM_01392 0.0 sbcC L ATPase involved in DNA repair
NGEPNEPM_01393 1.7e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NGEPNEPM_01394 0.0 lacL 3.2.1.23 G -beta-galactosidase
NGEPNEPM_01395 0.0 lacS G transporter
NGEPNEPM_01396 4.8e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NGEPNEPM_01397 1.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NGEPNEPM_01398 2.4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NGEPNEPM_01399 5.1e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NGEPNEPM_01400 6.8e-184 galR K Transcriptional regulator
NGEPNEPM_01401 7.1e-09 L Integrase core domain protein
NGEPNEPM_01402 9.2e-229 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NGEPNEPM_01403 1.9e-16 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NGEPNEPM_01404 1.2e-242 V abc transporter atp-binding protein
NGEPNEPM_01405 8.5e-70 V abc transporter atp-binding protein
NGEPNEPM_01406 1.5e-290 V abc transporter atp-binding protein
NGEPNEPM_01407 3.7e-235 L Transposase
NGEPNEPM_01408 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NGEPNEPM_01409 2.6e-78 L Transposase
NGEPNEPM_01410 1.3e-52 L Transposase
NGEPNEPM_01411 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NGEPNEPM_01412 2.5e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NGEPNEPM_01413 5.7e-132 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NGEPNEPM_01414 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NGEPNEPM_01417 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NGEPNEPM_01418 1.7e-174 vraS 2.7.13.3 T Histidine kinase
NGEPNEPM_01419 4.5e-118 yvqF KT membrane
NGEPNEPM_01420 1.4e-234 L Transposase
NGEPNEPM_01421 1.8e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
NGEPNEPM_01422 1.2e-129 stp 3.1.3.16 T phosphatase
NGEPNEPM_01423 6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NGEPNEPM_01424 5.1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NGEPNEPM_01425 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NGEPNEPM_01426 7.4e-44 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NGEPNEPM_01427 1.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NGEPNEPM_01428 7.4e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NGEPNEPM_01429 1.2e-149 XK27_02985 S overlaps another CDS with the same product name
NGEPNEPM_01430 7.6e-146 supH S overlaps another CDS with the same product name
NGEPNEPM_01431 9.5e-62 yvoA_1 K Transcriptional
NGEPNEPM_01432 5.3e-76 skfE V abc transporter atp-binding protein
NGEPNEPM_01433 4e-123 V ATPase activity
NGEPNEPM_01434 8e-171 oppF P Belongs to the ABC transporter superfamily
NGEPNEPM_01435 7.9e-202 oppD P Belongs to the ABC transporter superfamily
NGEPNEPM_01436 1.3e-165 amiD P ABC transporter (Permease
NGEPNEPM_01437 5.1e-268 amiC P ABC transporter (Permease
NGEPNEPM_01438 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NGEPNEPM_01439 1.1e-36 oppF P Belongs to the ABC transporter superfamily
NGEPNEPM_01440 7.7e-37 tatD L Hydrolase, tatd
NGEPNEPM_01441 3.7e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
NGEPNEPM_01442 7e-26 L Integrase core domain protein
NGEPNEPM_01443 4e-45 L transposase activity
NGEPNEPM_01444 3.3e-23 L transposase activity
NGEPNEPM_01445 1.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NGEPNEPM_01446 1.4e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NGEPNEPM_01447 4.9e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NGEPNEPM_01448 2.6e-115 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NGEPNEPM_01449 5.8e-103 yjbK S Adenylate cyclase
NGEPNEPM_01450 1.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGEPNEPM_01451 1.5e-203 iscS 2.8.1.7 E Cysteine desulfurase
NGEPNEPM_01452 7.6e-58 XK27_04120 S Putative amino acid metabolism
NGEPNEPM_01453 1.3e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NGEPNEPM_01454 2.2e-125 puuD T peptidase C26
NGEPNEPM_01455 8.4e-117 radC E Belongs to the UPF0758 family
NGEPNEPM_01456 0.0 rgpF M Rhamnan synthesis protein F
NGEPNEPM_01457 2.6e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NGEPNEPM_01458 1.5e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NGEPNEPM_01459 1.8e-142 rgpC GM Transport permease protein
NGEPNEPM_01460 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
NGEPNEPM_01461 4.1e-225 rgpA GT4 M Domain of unknown function (DUF1972)
NGEPNEPM_01462 6.8e-64 S Predicted membrane protein (DUF2142)
NGEPNEPM_01463 6.7e-36 S Predicted membrane protein (DUF2142)
NGEPNEPM_01464 4.7e-185 tagF 2.7.8.12 M Glycosyl transferase, family 2
NGEPNEPM_01465 7.3e-215 amrA S polysaccharide biosynthetic process
NGEPNEPM_01466 1.5e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
NGEPNEPM_01467 5.5e-124 ycbB S Glycosyl transferase family 2
NGEPNEPM_01468 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NGEPNEPM_01469 1.9e-245
NGEPNEPM_01470 5.7e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NGEPNEPM_01471 1.7e-249 M Psort location CytoplasmicMembrane, score
NGEPNEPM_01472 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NGEPNEPM_01473 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NGEPNEPM_01474 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NGEPNEPM_01475 3.3e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NGEPNEPM_01476 9.4e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NGEPNEPM_01477 1.5e-133 gltS ET Belongs to the bacterial solute-binding protein 3 family
NGEPNEPM_01478 5.8e-200 arcT 2.6.1.1 E Aminotransferase
NGEPNEPM_01479 2.3e-134 ET ABC transporter
NGEPNEPM_01480 1.3e-137 ET Belongs to the bacterial solute-binding protein 3 family
NGEPNEPM_01481 5.3e-46 mutT 3.6.1.55 F Nudix family
NGEPNEPM_01482 1.1e-254 L Recombinase
NGEPNEPM_01483 2.2e-301 L Resolvase, N-terminal domain protein
NGEPNEPM_01484 8.2e-301 L Psort location Cytoplasmic, score
NGEPNEPM_01486 2.9e-139 V ABC-2 type transporter
NGEPNEPM_01487 5.7e-119 P ABC-2 family transporter protein
NGEPNEPM_01488 3.9e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
NGEPNEPM_01489 0.0 Q Beta-ketoacyl synthase
NGEPNEPM_01490 0.0 Q Beta-ketoacyl synthase
NGEPNEPM_01491 1.3e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NGEPNEPM_01492 0.0 irp1 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGEPNEPM_01493 0.0 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGEPNEPM_01494 2.7e-92 K transcriptional regulator
NGEPNEPM_01495 1.1e-87 Q Thioesterase involved in non-ribosomal peptide biosynthesis
NGEPNEPM_01496 7.9e-96 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NGEPNEPM_01497 1.3e-308 U COG3843 Type IV secretory pathway, VirD2 components (relaxase)
NGEPNEPM_01498 3.4e-56 S Bacterial mobilisation protein (MobC)
NGEPNEPM_01499 5.7e-56 S Tn5252, Orf 10 protein
NGEPNEPM_01500 3.5e-120
NGEPNEPM_01501 8.1e-65
NGEPNEPM_01502 2.6e-178 3.6.4.12 L AAA domain
NGEPNEPM_01503 3.6e-272 L AAA ATPase domain
NGEPNEPM_01504 1.3e-125 K Peptidase S24-like
NGEPNEPM_01506 1.1e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_01507 1.8e-57
NGEPNEPM_01508 2.3e-44
NGEPNEPM_01510 2.6e-09 S DNA/RNA non-specific endonuclease
NGEPNEPM_01511 3e-36
NGEPNEPM_01512 8.4e-61
NGEPNEPM_01513 7.3e-17
NGEPNEPM_01514 4.2e-195 L Protein of unknown function (DUF3991)
NGEPNEPM_01515 7.1e-102
NGEPNEPM_01516 9.9e-35
NGEPNEPM_01517 3.5e-43
NGEPNEPM_01518 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
NGEPNEPM_01519 1.4e-90
NGEPNEPM_01521 0.0 sspC D Glucan-binding protein C
NGEPNEPM_01522 3.7e-235 L Transposase
NGEPNEPM_01523 1.2e-23 L Transposase
NGEPNEPM_01524 0.0 M CHAP domain protein
NGEPNEPM_01525 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
NGEPNEPM_01526 6.8e-54 XK27_00550 S PrgI family protein
NGEPNEPM_01527 6.7e-140 XK27_00555
NGEPNEPM_01528 3.2e-34 XK27_00560
NGEPNEPM_01529 0.0 traG U COG3505 Type IV secretory pathway, VirD4 components
NGEPNEPM_01530 2.2e-79
NGEPNEPM_01531 4.8e-97 3.4.11.19 V CAAX protease self-immunity
NGEPNEPM_01532 4.5e-38
NGEPNEPM_01533 5.1e-47
NGEPNEPM_01534 1.7e-43 XK27_00590
NGEPNEPM_01535 5.5e-261 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
NGEPNEPM_01536 1.5e-11
NGEPNEPM_01537 1.8e-126 repA S Replication initiator protein A
NGEPNEPM_01538 1.3e-18
NGEPNEPM_01539 1.1e-16 mutT 3.6.1.55 F Nudix family
NGEPNEPM_01540 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NGEPNEPM_01542 2.8e-20 S CAAX amino terminal protease family protein
NGEPNEPM_01543 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NGEPNEPM_01544 1.5e-77 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_01545 1.4e-234 L Transposase
NGEPNEPM_01546 3e-47 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_01547 1.1e-16 XK27_00735
NGEPNEPM_01548 3.7e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NGEPNEPM_01550 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NGEPNEPM_01553 1.2e-64 paaI Q protein possibly involved in aromatic compounds catabolism
NGEPNEPM_01554 1.4e-50 ycaO O OsmC-like protein
NGEPNEPM_01556 3.2e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
NGEPNEPM_01558 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
NGEPNEPM_01559 1.4e-301 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NGEPNEPM_01560 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGEPNEPM_01561 7.4e-109 3.1.3.18 S IA, variant 1
NGEPNEPM_01562 2.2e-117 lrgB M effector of murein hydrolase
NGEPNEPM_01563 7.7e-56 lrgA S Effector of murein hydrolase LrgA
NGEPNEPM_01565 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
NGEPNEPM_01566 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NGEPNEPM_01567 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGEPNEPM_01568 1.5e-103 wecD M Acetyltransferase (GNAT) domain
NGEPNEPM_01569 2.5e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NGEPNEPM_01570 1.4e-33 GK ROK family
NGEPNEPM_01571 2.7e-47 GK ROK family
NGEPNEPM_01572 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NGEPNEPM_01573 2.4e-143 XK27_08050 O HflC and HflK could regulate a protease
NGEPNEPM_01574 5e-201 potD P spermidine putrescine ABC transporter
NGEPNEPM_01575 1.2e-132 potC P ABC-type spermidine putrescine transport system, permease component II
NGEPNEPM_01576 1.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
NGEPNEPM_01577 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NGEPNEPM_01578 5.1e-170 murB 1.3.1.98 M cell wall formation
NGEPNEPM_01579 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NGEPNEPM_01580 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NGEPNEPM_01581 3.3e-296 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NGEPNEPM_01582 2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NGEPNEPM_01583 1.3e-99 folE 3.5.4.16 F gtp cyclohydrolase
NGEPNEPM_01584 0.0 ydaO E amino acid
NGEPNEPM_01585 9.4e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NGEPNEPM_01586 5.3e-37 ylqC L Belongs to the UPF0109 family
NGEPNEPM_01587 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NGEPNEPM_01588 5.8e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NGEPNEPM_01590 3.2e-155 xth 3.1.11.2 L exodeoxyribonuclease III
NGEPNEPM_01591 2.1e-74 S QueT transporter
NGEPNEPM_01592 3.8e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
NGEPNEPM_01593 1.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NGEPNEPM_01594 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NGEPNEPM_01595 1.3e-85 ccl S cog cog4708
NGEPNEPM_01596 2.7e-158 rbn E Belongs to the UPF0761 family
NGEPNEPM_01597 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NGEPNEPM_01598 1.1e-229 ytoI K transcriptional regulator containing CBS domains
NGEPNEPM_01599 4.4e-36 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NGEPNEPM_01600 5.3e-46 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NGEPNEPM_01601 3.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGEPNEPM_01602 0.0 comEC S Competence protein ComEC
NGEPNEPM_01603 1.3e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NGEPNEPM_01604 8.3e-142 plsC 2.3.1.51 I Acyltransferase
NGEPNEPM_01605 2.2e-11 nodB3 G Polysaccharide deacetylase
NGEPNEPM_01606 3e-96 nodB3 G Polysaccharide deacetylase
NGEPNEPM_01607 4.3e-138 yabB 2.1.1.223 L Methyltransferase
NGEPNEPM_01608 3.3e-40 yazA L endonuclease containing a URI domain
NGEPNEPM_01609 4.1e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NGEPNEPM_01610 1.2e-150 corA P CorA-like protein
NGEPNEPM_01611 2.5e-62 yjqA S Bacterial PH domain
NGEPNEPM_01612 4.8e-97 thiT S Thiamine transporter
NGEPNEPM_01613 5.8e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NGEPNEPM_01614 1.1e-92 ywaF S Integral membrane protein (intg_mem_TP0381)
NGEPNEPM_01615 1.8e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NGEPNEPM_01619 3.3e-155 cjaA ET ABC transporter substrate-binding protein
NGEPNEPM_01620 2.9e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_01621 7.8e-107 P ABC transporter (Permease
NGEPNEPM_01622 1.2e-112 papP P ABC transporter (Permease
NGEPNEPM_01623 1e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NGEPNEPM_01624 1e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
NGEPNEPM_01625 0.0 copA 3.6.3.54 P P-type ATPase
NGEPNEPM_01626 5.7e-71 copY K Copper transport repressor, CopY TcrY family
NGEPNEPM_01627 2.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NGEPNEPM_01628 1.7e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NGEPNEPM_01629 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NGEPNEPM_01630 2.7e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NGEPNEPM_01631 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NGEPNEPM_01632 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NGEPNEPM_01633 7.7e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NGEPNEPM_01634 3e-17 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NGEPNEPM_01635 8.6e-08 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NGEPNEPM_01636 0.0 ctpE P E1-E2 ATPase
NGEPNEPM_01637 2.3e-26
NGEPNEPM_01638 7.5e-137 KLT Protein tyrosine kinase
NGEPNEPM_01639 1.8e-157 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NGEPNEPM_01640 8.9e-105 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NGEPNEPM_01641 3.9e-31
NGEPNEPM_01642 1.2e-40
NGEPNEPM_01643 1.7e-220 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_01644 1.7e-109 K Peptidase S24-like
NGEPNEPM_01645 6.6e-127 E IrrE N-terminal-like domain
NGEPNEPM_01648 1.5e-45 K Transcriptional
NGEPNEPM_01649 1.3e-42
NGEPNEPM_01650 1.2e-71
NGEPNEPM_01651 7e-274 ydcQ D Ftsk spoiiie family protein
NGEPNEPM_01652 9.2e-223 K Replication initiation factor
NGEPNEPM_01653 1.3e-32
NGEPNEPM_01654 4.5e-92
NGEPNEPM_01655 3.1e-160 S Conjugative transposon protein TcpC
NGEPNEPM_01656 1.2e-32
NGEPNEPM_01657 1.8e-66 S TcpE family
NGEPNEPM_01658 0.0 yddE S AAA-like domain
NGEPNEPM_01659 3.8e-252
NGEPNEPM_01660 2.2e-29
NGEPNEPM_01661 4e-169 isp2 S pathogenesis
NGEPNEPM_01662 3.9e-19 S Domain of unknown function (DUF3173)
NGEPNEPM_01663 1e-183 L Belongs to the 'phage' integrase family
NGEPNEPM_01664 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NGEPNEPM_01666 8.2e-28 L transposase activity
NGEPNEPM_01667 3.7e-33 K transcriptional regulator, MerR family
NGEPNEPM_01668 3.7e-235 L Transposase
NGEPNEPM_01669 7e-104 dnaQ 2.7.7.7 L DNA polymerase III
NGEPNEPM_01670 7.2e-39 WQ51_02910 S Protein of unknown function, DUF536
NGEPNEPM_01671 7.4e-64 XK27_02560 S cog cog2151
NGEPNEPM_01672 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NGEPNEPM_01673 1.7e-226 ytfP S Flavoprotein
NGEPNEPM_01675 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NGEPNEPM_01676 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NGEPNEPM_01677 2.1e-180 ecsB U ABC transporter
NGEPNEPM_01678 4.9e-131 ecsA V abc transporter atp-binding protein
NGEPNEPM_01679 8.6e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NGEPNEPM_01680 1.8e-10
NGEPNEPM_01681 1.4e-56 S CD20-like family
NGEPNEPM_01682 7.3e-107
NGEPNEPM_01683 3.7e-235 L Transposase
NGEPNEPM_01684 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NGEPNEPM_01685 2e-197 ylbM S Belongs to the UPF0348 family
NGEPNEPM_01686 3.2e-138 yqeM Q Methyltransferase domain protein
NGEPNEPM_01687 1.3e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NGEPNEPM_01688 2.9e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NGEPNEPM_01689 4.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NGEPNEPM_01690 5.9e-49 yhbY J RNA-binding protein
NGEPNEPM_01691 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NGEPNEPM_01692 2.6e-97 yqeG S hydrolase of the HAD superfamily
NGEPNEPM_01693 4e-146 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NGEPNEPM_01694 8.8e-32
NGEPNEPM_01695 8.1e-271 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGEPNEPM_01696 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NGEPNEPM_01697 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGEPNEPM_01698 4.2e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NGEPNEPM_01699 6.2e-52 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGEPNEPM_01700 6.5e-14 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGEPNEPM_01701 1.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NGEPNEPM_01702 2.4e-153 hlpA M Belongs to the NlpA lipoprotein family
NGEPNEPM_01703 2.7e-97 pncA Q isochorismatase
NGEPNEPM_01704 8.4e-137 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NGEPNEPM_01705 5.8e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NGEPNEPM_01706 2.4e-75 XK27_03180 T universal stress protein
NGEPNEPM_01708 1.1e-149 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NGEPNEPM_01709 1.5e-222 L Transposase
NGEPNEPM_01710 2.1e-236 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NGEPNEPM_01711 1.5e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NGEPNEPM_01712 0.0 yjcE P NhaP-type Na H and K H antiporters
NGEPNEPM_01714 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
NGEPNEPM_01715 1.4e-183 yhcC S radical SAM protein
NGEPNEPM_01716 6.5e-44
NGEPNEPM_01717 4.3e-164 L Transposase
NGEPNEPM_01718 1.1e-192 ylbL T Belongs to the peptidase S16 family
NGEPNEPM_01719 5.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NGEPNEPM_01720 2.1e-91 rsmD 2.1.1.171 L Methyltransferase
NGEPNEPM_01721 2.8e-168 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NGEPNEPM_01722 1.6e-08 S Protein of unknown function (DUF4059)
NGEPNEPM_01723 5.5e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
NGEPNEPM_01724 2.8e-160 yxeN P ABC transporter (Permease
NGEPNEPM_01725 7e-150 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NGEPNEPM_01728 2.8e-199 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGEPNEPM_01729 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NGEPNEPM_01730 3.6e-64 cah 4.2.1.1 P carbonic anhydrase
NGEPNEPM_01731 1.7e-38 cah 4.2.1.1 P carbonate dehydratase activity
NGEPNEPM_01732 3e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NGEPNEPM_01733 1.9e-48 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NGEPNEPM_01734 3.4e-32 D nuclear chromosome segregation
NGEPNEPM_01735 1.7e-31 L DNA integration
NGEPNEPM_01736 6.9e-57 L Phage integrase family
NGEPNEPM_01737 3e-96 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
NGEPNEPM_01738 4.9e-126 ybbM S transport system, permease component
NGEPNEPM_01739 1.8e-116 ybbL S abc transporter atp-binding protein
NGEPNEPM_01740 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NGEPNEPM_01741 1e-47 cppA E CppA N-terminal
NGEPNEPM_01742 3.2e-68 cppA E CppA N-terminal
NGEPNEPM_01743 1.1e-231 L Transposase
NGEPNEPM_01744 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NGEPNEPM_01745 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NGEPNEPM_01748 5.7e-46 spiA K sequence-specific DNA binding
NGEPNEPM_01749 9.5e-140 blpT
NGEPNEPM_01758 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
NGEPNEPM_01761 1.6e-134 agrA KT phosphorelay signal transduction system
NGEPNEPM_01762 2.9e-238 blpH 2.7.13.3 T protein histidine kinase activity
NGEPNEPM_01764 1.6e-236 mesE M Transport protein ComB
NGEPNEPM_01765 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGEPNEPM_01767 0.0 mdlB V abc transporter atp-binding protein
NGEPNEPM_01768 0.0 mdlA V abc transporter atp-binding protein
NGEPNEPM_01770 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NGEPNEPM_01771 6.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NGEPNEPM_01772 2.4e-66 yutD J protein conserved in bacteria
NGEPNEPM_01773 1.1e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NGEPNEPM_01775 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NGEPNEPM_01776 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NGEPNEPM_01777 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NGEPNEPM_01778 4.3e-47 ftsL D cell division protein FtsL
NGEPNEPM_01779 2e-156 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NGEPNEPM_01780 1.6e-65
NGEPNEPM_01781 7.4e-27
NGEPNEPM_01782 1.2e-30
NGEPNEPM_01783 2.4e-30 yhaI J Protein of unknown function (DUF805)
NGEPNEPM_01784 8.8e-223 L Transposase
NGEPNEPM_01785 3.6e-16 D nuclear chromosome segregation
NGEPNEPM_01786 5.8e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NGEPNEPM_01787 4.5e-138 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NGEPNEPM_01788 8.6e-274 XK27_00765
NGEPNEPM_01789 3.7e-131 ecsA_2 V abc transporter atp-binding protein
NGEPNEPM_01790 3.4e-108 S Protein of unknown function (DUF554)
NGEPNEPM_01791 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NGEPNEPM_01792 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NGEPNEPM_01793 5.7e-93 liaI S membrane
NGEPNEPM_01794 7e-10 XK27_02470 K LytTr DNA-binding domain protein
NGEPNEPM_01795 3e-53 KT response to antibiotic
NGEPNEPM_01796 1.4e-08 KT response to antibiotic
NGEPNEPM_01797 9.1e-18 KT response to antibiotic
NGEPNEPM_01798 1.5e-76 yebC M Membrane
NGEPNEPM_01799 6.9e-251 XK27_03190 S hydrolases of the HAD superfamily
NGEPNEPM_01800 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NGEPNEPM_01801 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NGEPNEPM_01802 1.2e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NGEPNEPM_01803 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NGEPNEPM_01804 1.2e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NGEPNEPM_01805 1.6e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NGEPNEPM_01806 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NGEPNEPM_01808 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NGEPNEPM_01809 2.9e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NGEPNEPM_01810 0.0 scrA 2.7.1.211 G pts system
NGEPNEPM_01811 1e-289 scrB 3.2.1.26 GH32 G invertase
NGEPNEPM_01812 6.4e-179 scrR K Transcriptional
NGEPNEPM_01813 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NGEPNEPM_01814 3.4e-62 yqhY S protein conserved in bacteria
NGEPNEPM_01815 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NGEPNEPM_01816 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
NGEPNEPM_01817 1.5e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NGEPNEPM_01819 3.1e-57 V 'abc transporter, ATP-binding protein
NGEPNEPM_01820 2.6e-44 V 'abc transporter, ATP-binding protein
NGEPNEPM_01825 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NGEPNEPM_01826 1.3e-165 corA P COG0598 Mg2 and Co2 transporters
NGEPNEPM_01827 1.3e-122 XK27_01040 S Pfam PF06570
NGEPNEPM_01829 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NGEPNEPM_01830 1e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NGEPNEPM_01831 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NGEPNEPM_01832 4.7e-41 XK27_05745
NGEPNEPM_01833 3.6e-229 mutY L A G-specific adenine glycosylase
NGEPNEPM_01836 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NGEPNEPM_01837 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NGEPNEPM_01838 6.7e-93 cvpA S toxin biosynthetic process
NGEPNEPM_01839 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NGEPNEPM_01840 3.4e-158 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGEPNEPM_01841 6.9e-110 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NGEPNEPM_01842 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NGEPNEPM_01843 6.3e-46 azlD E branched-chain amino acid
NGEPNEPM_01844 3e-114 azlC E AzlC protein
NGEPNEPM_01845 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NGEPNEPM_01846 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NGEPNEPM_01847 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NGEPNEPM_01848 2.5e-33 ykzG S Belongs to the UPF0356 family
NGEPNEPM_01849 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGEPNEPM_01850 2.4e-41 pscB M CHAP domain protein
NGEPNEPM_01851 4.9e-262 glnA 6.3.1.2 E glutamine synthetase
NGEPNEPM_01852 8.5e-63 glnR K Transcriptional regulator
NGEPNEPM_01853 2.3e-87 S Fusaric acid resistance protein-like
NGEPNEPM_01854 1.8e-223 L Transposase
NGEPNEPM_01855 3e-94 L Transposase
NGEPNEPM_01856 1.6e-219 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NGEPNEPM_01857 1.1e-23 L Transposase
NGEPNEPM_01858 3.5e-14 L transposase activity
NGEPNEPM_01859 7e-26 L Integrase core domain protein
NGEPNEPM_01860 1.8e-22 L Transposase IS116 IS110 IS902
NGEPNEPM_01861 3.4e-68 L transposase IS116 IS110 IS902 family
NGEPNEPM_01862 3.9e-75 L COG3547 Transposase and inactivated derivatives
NGEPNEPM_01863 1.1e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NGEPNEPM_01864 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NGEPNEPM_01865 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NGEPNEPM_01866 7.7e-65 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NGEPNEPM_01867 2e-141 purR 2.4.2.7 F operon repressor
NGEPNEPM_01868 1.8e-173 cbf S 3'-5' exoribonuclease yhaM
NGEPNEPM_01869 5.5e-170 rmuC S RmuC domain protein
NGEPNEPM_01870 5.9e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
NGEPNEPM_01871 5.1e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NGEPNEPM_01872 1.3e-159 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NGEPNEPM_01874 9.3e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NGEPNEPM_01875 2.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NGEPNEPM_01876 1.3e-142 tatD L Hydrolase, tatd
NGEPNEPM_01877 1e-44 yccU S CoA-binding protein
NGEPNEPM_01878 1.1e-50 trxA O Belongs to the thioredoxin family
NGEPNEPM_01879 7.9e-140 S Macro domain protein
NGEPNEPM_01880 1.8e-226 L Transposase
NGEPNEPM_01881 3.1e-16 IQ Thioesterase
NGEPNEPM_01882 3.1e-08 L thioesterase
NGEPNEPM_01883 6.5e-54 bta 1.8.1.8 CO cell redox homeostasis
NGEPNEPM_01887 3.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NGEPNEPM_01888 1e-13 rpmH J Ribosomal protein L34
NGEPNEPM_01889 1e-163 S Uncharacterised protein family (UPF0236)
NGEPNEPM_01890 8.6e-127 S Fic/DOC family
NGEPNEPM_01892 1.1e-112 D CobQ CobB MinD ParA nucleotide binding domain protein
NGEPNEPM_01894 1.8e-72 tnpR L Resolvase, N terminal domain
NGEPNEPM_01896 3.4e-281 U relaxase
NGEPNEPM_01897 2.2e-26 S Bacterial mobilisation protein (MobC)
NGEPNEPM_01899 0.0 2.1.1.72, 3.1.21.3 L Psort location Cytoplasmic, score
NGEPNEPM_01901 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGEPNEPM_01905 0.0 U An automated process has identified a potential problem with this gene model
NGEPNEPM_01906 5.6e-46 S Protein of unknown function (DUF3801)
NGEPNEPM_01907 5.7e-56
NGEPNEPM_01909 1.8e-63 ssb L single-stranded DNA binding
NGEPNEPM_01910 1.1e-104
NGEPNEPM_01911 0.0 M CHAP domain protein
NGEPNEPM_01912 0.0 U Psort location Cytoplasmic, score
NGEPNEPM_01913 2.2e-44 S PrgI family protein
NGEPNEPM_01914 3.3e-98
NGEPNEPM_01915 3e-24
NGEPNEPM_01916 8.9e-15
NGEPNEPM_01917 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NGEPNEPM_01918 1.6e-18 MU outer membrane autotransporter barrel domain protein
NGEPNEPM_01919 2.5e-10
NGEPNEPM_01921 3.2e-167 S Replication initiator protein A
NGEPNEPM_01923 3.5e-183 jag S RNA-binding protein
NGEPNEPM_01924 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGEPNEPM_01925 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NGEPNEPM_01926 2.1e-263 argH 4.3.2.1 E Argininosuccinate lyase
NGEPNEPM_01927 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NGEPNEPM_01928 3.3e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NGEPNEPM_01929 1.6e-62 amiA E transmembrane transport
NGEPNEPM_01930 2.1e-25 amiA E transmembrane transport
NGEPNEPM_01931 3.8e-81 amiA E ABC transporter, substrate-binding protein, family 5
NGEPNEPM_01932 4.2e-33 amiA E ABC transporter, substrate-binding protein, family 5
NGEPNEPM_01933 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NGEPNEPM_01934 3.1e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NGEPNEPM_01935 4.6e-50 S Protein of unknown function (DUF3397)
NGEPNEPM_01936 1.3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NGEPNEPM_01937 1.5e-39 WQ51_05710 S Mitochondrial biogenesis AIM24
NGEPNEPM_01938 1.1e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
NGEPNEPM_01939 2.3e-218 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NGEPNEPM_01940 3.8e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NGEPNEPM_01941 2.6e-104 XK27_09620 S reductase
NGEPNEPM_01942 1e-221 XK27_09615 C reductase
NGEPNEPM_01944 2.1e-71 fnt P Formate nitrite transporter
NGEPNEPM_01945 9e-76 XK27_08585 S Psort location CytoplasmicMembrane, score
NGEPNEPM_01946 7e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NGEPNEPM_01947 1.2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NGEPNEPM_01948 1.2e-115 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NGEPNEPM_01949 4.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NGEPNEPM_01950 3.9e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NGEPNEPM_01951 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NGEPNEPM_01952 3.2e-117 S HAD hydrolase, family IA, variant
NGEPNEPM_01953 1.7e-156 rrmA 2.1.1.187 Q methyltransferase
NGEPNEPM_01956 6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NGEPNEPM_01957 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NGEPNEPM_01958 4.1e-36 yeeD O sulfur carrier activity
NGEPNEPM_01959 1.3e-190 yeeE S Sulphur transport
NGEPNEPM_01960 3.9e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGEPNEPM_01961 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NGEPNEPM_01962 1.8e-09 S Domain of unknown function (DUF4651)
NGEPNEPM_01963 1.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NGEPNEPM_01964 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NGEPNEPM_01965 2.8e-109 S CAAX amino terminal protease family protein
NGEPNEPM_01966 1.3e-25 lanR K sequence-specific DNA binding
NGEPNEPM_01967 1.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NGEPNEPM_01968 2.7e-174 ytxK 2.1.1.72 L DNA methylase
NGEPNEPM_01969 1.1e-12 comGF U Putative Competence protein ComGF
NGEPNEPM_01970 4.9e-70 comGF U Competence protein ComGF
NGEPNEPM_01971 2.4e-15 NU Type II secretory pathway pseudopilin
NGEPNEPM_01972 2.3e-57 cglD NU Competence protein
NGEPNEPM_01973 5.5e-42 comGC U Required for transformation and DNA binding
NGEPNEPM_01974 7.2e-153 cglB NU type II secretion system
NGEPNEPM_01975 1.2e-169 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NGEPNEPM_01976 4.4e-64 S cog cog4699
NGEPNEPM_01977 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGEPNEPM_01978 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGEPNEPM_01979 5.6e-180 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NGEPNEPM_01980 2.7e-236 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NGEPNEPM_01981 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NGEPNEPM_01982 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NGEPNEPM_01983 3.2e-75 ilvN 2.2.1.6 E Acetolactate synthase
NGEPNEPM_01984 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NGEPNEPM_01985 1.3e-243 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NGEPNEPM_01986 6.2e-45 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NGEPNEPM_01987 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
NGEPNEPM_01988 1.8e-57 asp S cog cog1302
NGEPNEPM_01989 2.7e-225 norN V Mate efflux family protein
NGEPNEPM_01990 2.4e-273 thrC 4.2.3.1 E Threonine synthase
NGEPNEPM_01991 4.6e-51 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGEPNEPM_01992 1.6e-42 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGEPNEPM_01993 4.1e-30 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGEPNEPM_01994 1.7e-53 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGEPNEPM_01995 1.1e-21 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGEPNEPM_01996 1.4e-50 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NGEPNEPM_01997 0.0 pepO 3.4.24.71 O Peptidase family M13
NGEPNEPM_01998 2.2e-35 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NGEPNEPM_01999 7.9e-63 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NGEPNEPM_02000 5.5e-80 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NGEPNEPM_02001 6.5e-46 treB 2.7.1.201 G pts system
NGEPNEPM_02002 1.4e-54 treB 2.7.1.201 G PTS System
NGEPNEPM_02003 2.9e-112 treR K trehalose operon
NGEPNEPM_02004 5.7e-95 ywlG S Belongs to the UPF0340 family
NGEPNEPM_02007 7.8e-40 L Transposase
NGEPNEPM_02008 1e-153 L Integrase core domain protein
NGEPNEPM_02009 1.5e-22 V ABC transporter (permease)
NGEPNEPM_02010 9e-22 V ABC transporter (permease)
NGEPNEPM_02011 3.6e-56 V ABC transporter, ATP-binding protein
NGEPNEPM_02012 1.6e-20
NGEPNEPM_02013 1.1e-75 sagB C Nitroreductase family
NGEPNEPM_02014 2.7e-84 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
NGEPNEPM_02015 2.5e-32 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
NGEPNEPM_02016 7.6e-46
NGEPNEPM_02017 4.6e-15
NGEPNEPM_02018 5.1e-09
NGEPNEPM_02019 5.1e-223 L Transposase
NGEPNEPM_02020 2.4e-64 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NGEPNEPM_02021 4.8e-50 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NGEPNEPM_02022 1.1e-217 opuCA 2.7.7.7 E abc transporter atp-binding protein
NGEPNEPM_02023 4.8e-106 opuCB P ABC transporter
NGEPNEPM_02024 1.8e-117 opuCC P ABC-type proline glycine betaine transport systems, permease component
NGEPNEPM_02025 7.2e-113 opuCD P ABC-type proline glycine betaine transport systems permease component
NGEPNEPM_02026 7.2e-71 yvdD 3.2.2.10 L Belongs to the LOG family
NGEPNEPM_02027 4.5e-88 2.3.1.128 K Acetyltransferase GNAT Family
NGEPNEPM_02028 7.9e-224 L Transposase
NGEPNEPM_02029 4.2e-192 L DNA integration
NGEPNEPM_02030 5.3e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
NGEPNEPM_02032 4e-129 6.3.2.2 H gamma-glutamylcysteine synthetase
NGEPNEPM_02033 5.7e-40 6.3.2.2 H gamma-glutamylcysteine synthetase
NGEPNEPM_02034 3.1e-38 L PFAM Integrase, catalytic core
NGEPNEPM_02035 5.7e-45 L PFAM Integrase, catalytic core
NGEPNEPM_02036 4.8e-51 L PFAM Integrase, catalytic core
NGEPNEPM_02037 1.3e-61 rplQ J ribosomal protein l17
NGEPNEPM_02038 9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGEPNEPM_02039 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NGEPNEPM_02040 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NGEPNEPM_02041 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NGEPNEPM_02042 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NGEPNEPM_02043 4.7e-117 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NGEPNEPM_02044 1.1e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NGEPNEPM_02045 4.4e-58 rplO J binds to the 23S rRNA
NGEPNEPM_02046 2.5e-23 rpmD J ribosomal protein l30
NGEPNEPM_02047 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NGEPNEPM_02048 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NGEPNEPM_02049 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NGEPNEPM_02050 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NGEPNEPM_02051 2.4e-26 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NGEPNEPM_02052 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NGEPNEPM_02053 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NGEPNEPM_02054 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NGEPNEPM_02055 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NGEPNEPM_02056 2.1e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NGEPNEPM_02057 1.5e-68 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NGEPNEPM_02058 8.3e-114 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NGEPNEPM_02059 8.1e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NGEPNEPM_02060 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NGEPNEPM_02061 6.3e-151 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NGEPNEPM_02062 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NGEPNEPM_02063 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NGEPNEPM_02064 2e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NGEPNEPM_02065 4.1e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
NGEPNEPM_02066 9.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NGEPNEPM_02067 0.0 XK27_09800 I Acyltransferase
NGEPNEPM_02068 1.7e-35 XK27_09805 S MORN repeat protein
NGEPNEPM_02069 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NGEPNEPM_02070 2.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NGEPNEPM_02071 1.8e-226 L Transposase
NGEPNEPM_02072 1e-48 adk 2.7.4.3 F topology modulation protein
NGEPNEPM_02074 2.2e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NGEPNEPM_02075 1.9e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NGEPNEPM_02076 2.2e-44 yrzL S Belongs to the UPF0297 family
NGEPNEPM_02077 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NGEPNEPM_02078 4.2e-44 yrzB S Belongs to the UPF0473 family
NGEPNEPM_02079 2.6e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
NGEPNEPM_02080 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NGEPNEPM_02081 2.8e-13
NGEPNEPM_02082 1.2e-88 XK27_10930 K acetyltransferase
NGEPNEPM_02083 3.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NGEPNEPM_02084 1.2e-146 yaaA S Belongs to the UPF0246 family
NGEPNEPM_02085 3.8e-168 XK27_01785 S cog cog1284
NGEPNEPM_02086 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NGEPNEPM_02088 2.3e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
NGEPNEPM_02089 2e-213 metE 2.1.1.14 E Methionine synthase
NGEPNEPM_02090 2.9e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NGEPNEPM_02091 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NGEPNEPM_02094 3.9e-143 yegS 2.7.1.107 I Diacylglycerol kinase
NGEPNEPM_02095 1.4e-91 S Hydrophobic domain protein
NGEPNEPM_02098 1.1e-26 S Membrane
NGEPNEPM_02099 4.5e-100
NGEPNEPM_02100 6.7e-23 S Small integral membrane protein
NGEPNEPM_02101 9.3e-69 M Protein conserved in bacteria
NGEPNEPM_02102 5e-09 K CsbD-like
NGEPNEPM_02103 2.6e-77 nudL L hydrolase
NGEPNEPM_02104 7e-12 K negative regulation of transcription, DNA-templated
NGEPNEPM_02106 9.4e-61 S Putative adhesin
NGEPNEPM_02107 1.5e-21 S Putative adhesin
NGEPNEPM_02108 1.9e-155 XK27_06930 V domain protein
NGEPNEPM_02109 3.5e-94 XK27_06935 K transcriptional regulator
NGEPNEPM_02110 1.8e-13 ypaA M Membrane
NGEPNEPM_02112 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NGEPNEPM_02113 2.4e-47 veg S Biofilm formation stimulator VEG
NGEPNEPM_02114 2.1e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NGEPNEPM_02115 8.5e-73 rplI J binds to the 23S rRNA
NGEPNEPM_02116 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NGEPNEPM_02117 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NGEPNEPM_02118 8.9e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NGEPNEPM_02119 0.0 S Bacterial membrane protein, YfhO
NGEPNEPM_02120 1.8e-89 isaA GH23 M Immunodominant staphylococcal antigen A
NGEPNEPM_02121 6.6e-80 lytE M LysM domain protein
NGEPNEPM_02122 1.4e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGEPNEPM_02123 1.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGEPNEPM_02124 3.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGEPNEPM_02125 5.5e-87 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NGEPNEPM_02126 8.9e-132 ymfM S sequence-specific DNA binding
NGEPNEPM_02127 1.2e-154 ymfH S Peptidase M16
NGEPNEPM_02128 1.5e-71 ymfH S Peptidase M16
NGEPNEPM_02129 1e-229 ymfF S Peptidase M16
NGEPNEPM_02130 2.9e-42 yaaA S S4 domain protein YaaA
NGEPNEPM_02131 1.9e-195 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NGEPNEPM_02132 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NGEPNEPM_02133 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NGEPNEPM_02134 5.4e-153 yvjA S membrane
NGEPNEPM_02135 2.5e-305 ybiT S abc transporter atp-binding protein
NGEPNEPM_02136 0.0 XK27_10405 S Bacterial membrane protein YfhO
NGEPNEPM_02140 2.7e-115 yoaK S Protein of unknown function (DUF1275)
NGEPNEPM_02141 8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NGEPNEPM_02142 1.1e-183 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NGEPNEPM_02143 1.6e-132 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)