ORF_ID e_value Gene_name EC_number CAZy COGs Description
KOOEGFKL_00001 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOOEGFKL_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOOEGFKL_00003 4.1e-29 yyzM S Protein conserved in bacteria
KOOEGFKL_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOOEGFKL_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOOEGFKL_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOOEGFKL_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KOOEGFKL_00008 2.7e-61 divIC D Septum formation initiator
KOOEGFKL_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KOOEGFKL_00011 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOOEGFKL_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KOOEGFKL_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOOEGFKL_00014 2.5e-136 L Transposase
KOOEGFKL_00015 1.9e-46 L transposase activity
KOOEGFKL_00016 5.7e-23 L Transposase
KOOEGFKL_00017 2.7e-28 L transposition
KOOEGFKL_00018 4.3e-96 L Transposase and inactivated derivatives
KOOEGFKL_00031 5.3e-11
KOOEGFKL_00037 5.5e-139 mreC M Involved in formation and maintenance of cell shape
KOOEGFKL_00038 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KOOEGFKL_00039 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
KOOEGFKL_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOOEGFKL_00041 2.9e-218 araT 2.6.1.1 E Aminotransferase
KOOEGFKL_00042 7e-144 recO L Involved in DNA repair and RecF pathway recombination
KOOEGFKL_00043 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KOOEGFKL_00044 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOOEGFKL_00045 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KOOEGFKL_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOOEGFKL_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOOEGFKL_00048 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KOOEGFKL_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KOOEGFKL_00050 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KOOEGFKL_00051 1.8e-78 L transposase activity
KOOEGFKL_00052 1.9e-50 L transposition
KOOEGFKL_00053 1.8e-33 L Transposase and inactivated derivatives
KOOEGFKL_00054 7.5e-160 S CHAP domain
KOOEGFKL_00055 6.5e-240 purD 6.3.4.13 F Belongs to the GARS family
KOOEGFKL_00056 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOOEGFKL_00057 2.9e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOOEGFKL_00058 1.7e-139 1.1.1.169 H Ketopantoate reductase
KOOEGFKL_00059 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KOOEGFKL_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KOOEGFKL_00061 9.8e-95 L Transposase
KOOEGFKL_00062 2.1e-07 L Transposase
KOOEGFKL_00063 8.2e-70 argR K Regulates arginine biosynthesis genes
KOOEGFKL_00064 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KOOEGFKL_00065 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KOOEGFKL_00066 5.7e-36 S Protein of unknown function (DUF3021)
KOOEGFKL_00067 3.2e-62 KT phosphorelay signal transduction system
KOOEGFKL_00069 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KOOEGFKL_00071 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOOEGFKL_00072 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KOOEGFKL_00073 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KOOEGFKL_00074 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOOEGFKL_00075 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KOOEGFKL_00081 2.6e-10
KOOEGFKL_00084 1.9e-07
KOOEGFKL_00089 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOOEGFKL_00090 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KOOEGFKL_00091 5.5e-36 XK27_02060 S Transglycosylase associated protein
KOOEGFKL_00092 5.7e-55 badR K DNA-binding transcription factor activity
KOOEGFKL_00093 3.9e-96 S reductase
KOOEGFKL_00094 2.2e-87 L Integrase core domain protein
KOOEGFKL_00095 6.4e-41 L transposition
KOOEGFKL_00097 4.2e-77 yocD 3.4.17.13 V carboxypeptidase activity
KOOEGFKL_00098 9.2e-92 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KOOEGFKL_00100 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KOOEGFKL_00101 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOOEGFKL_00102 1.1e-83 S Putative small multi-drug export protein
KOOEGFKL_00103 6.2e-76 ctsR K Belongs to the CtsR family
KOOEGFKL_00104 0.0 clpC O Belongs to the ClpA ClpB family
KOOEGFKL_00105 1.3e-152 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOOEGFKL_00106 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOOEGFKL_00107 3.9e-122 L Transposase
KOOEGFKL_00108 1.2e-165 L integrase core domain
KOOEGFKL_00109 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOOEGFKL_00110 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KOOEGFKL_00111 8.5e-142 S SseB protein N-terminal domain
KOOEGFKL_00112 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KOOEGFKL_00113 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOOEGFKL_00114 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KOOEGFKL_00117 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOOEGFKL_00118 1.6e-91 yacP S RNA-binding protein containing a PIN domain
KOOEGFKL_00119 3.4e-155 degV S DegV family
KOOEGFKL_00121 3.2e-33 K helix-turn-helix
KOOEGFKL_00122 3.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOOEGFKL_00123 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOOEGFKL_00124 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KOOEGFKL_00125 2e-228 L the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_00126 4.1e-36 K sequence-specific DNA binding
KOOEGFKL_00128 3.1e-119 S Lantibiotic dehydratase, C terminus
KOOEGFKL_00129 4.1e-234 S Lantibiotic dehydratase, C terminus
KOOEGFKL_00130 1.3e-224 spaC2 V Lanthionine synthetase C family protein
KOOEGFKL_00131 9.5e-183 EGP Major facilitator Superfamily
KOOEGFKL_00132 1.6e-91 3.6.4.12 K Divergent AAA domain protein
KOOEGFKL_00133 1.1e-223 int L Belongs to the 'phage' integrase family
KOOEGFKL_00134 7.4e-40 S Helix-turn-helix domain
KOOEGFKL_00135 9e-119
KOOEGFKL_00136 2.3e-41
KOOEGFKL_00138 1.9e-26 isp2 S pathogenesis
KOOEGFKL_00139 5.8e-67 tnp L Transposase
KOOEGFKL_00140 5.8e-48 tnp L Transposase
KOOEGFKL_00141 2.7e-42 capA M Bacterial capsule synthesis protein PGA_cap
KOOEGFKL_00142 4.3e-109 capA M Bacterial capsule synthesis protein
KOOEGFKL_00143 8.7e-43 capA M Bacterial capsule synthesis protein
KOOEGFKL_00144 3.6e-39 gcvR T UPF0237 protein
KOOEGFKL_00145 1.7e-243 XK27_08635 S UPF0210 protein
KOOEGFKL_00146 3.5e-134 ais G Phosphoglycerate mutase
KOOEGFKL_00147 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KOOEGFKL_00148 1.7e-102 acmA 3.2.1.17 NU amidase activity
KOOEGFKL_00149 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOOEGFKL_00150 1.5e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOOEGFKL_00151 3.7e-297 dnaK O Heat shock 70 kDa protein
KOOEGFKL_00152 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOOEGFKL_00153 1.7e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOOEGFKL_00154 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KOOEGFKL_00155 1.7e-60 hmpT S membrane
KOOEGFKL_00168 2.4e-48 L Transposase
KOOEGFKL_00169 9.9e-19 S Domain of unknown function (DUF4649)
KOOEGFKL_00170 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KOOEGFKL_00171 4.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KOOEGFKL_00172 1.3e-87
KOOEGFKL_00173 1.6e-77 sigH K DNA-templated transcription, initiation
KOOEGFKL_00174 1e-148 ykuT M mechanosensitive ion channel
KOOEGFKL_00175 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOOEGFKL_00176 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KOOEGFKL_00177 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOOEGFKL_00178 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
KOOEGFKL_00179 1.6e-79 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KOOEGFKL_00180 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
KOOEGFKL_00181 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOOEGFKL_00182 1.6e-29 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KOOEGFKL_00183 2.6e-138 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KOOEGFKL_00184 3.3e-187 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KOOEGFKL_00185 1.7e-81 nrdI F Belongs to the NrdI family
KOOEGFKL_00186 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOOEGFKL_00187 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOOEGFKL_00188 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KOOEGFKL_00189 3.4e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KOOEGFKL_00190 1e-60 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KOOEGFKL_00191 8.7e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KOOEGFKL_00192 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KOOEGFKL_00193 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOOEGFKL_00194 7.6e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KOOEGFKL_00195 9.3e-201 yhjX P Major Facilitator
KOOEGFKL_00196 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOOEGFKL_00197 1.4e-93 V VanZ like family
KOOEGFKL_00199 1e-123 glnQ E abc transporter atp-binding protein
KOOEGFKL_00200 2.6e-275 glnP P ABC transporter
KOOEGFKL_00201 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOOEGFKL_00202 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KOOEGFKL_00203 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
KOOEGFKL_00204 2.2e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KOOEGFKL_00205 6.9e-234 sufD O assembly protein SufD
KOOEGFKL_00206 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOOEGFKL_00207 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
KOOEGFKL_00208 2.2e-273 sufB O assembly protein SufB
KOOEGFKL_00209 4.2e-19 oppA E ABC transporter substrate-binding protein
KOOEGFKL_00210 4.7e-140 oppA E ABC transporter substrate-binding protein
KOOEGFKL_00211 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOOEGFKL_00212 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOOEGFKL_00213 6.3e-47 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOOEGFKL_00214 6.5e-58 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOOEGFKL_00215 8e-28 oppD P Belongs to the ABC transporter superfamily
KOOEGFKL_00216 5.5e-32 oppD P Belongs to the ABC transporter superfamily
KOOEGFKL_00217 2.8e-67 oppD P Belongs to the ABC transporter superfamily
KOOEGFKL_00218 1.3e-44 oppD P Belongs to the ABC transporter superfamily
KOOEGFKL_00219 4.3e-164 oppF P Belongs to the ABC transporter superfamily
KOOEGFKL_00222 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KOOEGFKL_00223 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOOEGFKL_00224 6e-128 K sequence-specific DNA binding
KOOEGFKL_00225 0.0 KLT serine threonine protein kinase
KOOEGFKL_00226 4.2e-223 EGP Major facilitator Superfamily
KOOEGFKL_00227 3.1e-72 adcR K transcriptional
KOOEGFKL_00228 1.4e-135 adcC P ABC transporter, ATP-binding protein
KOOEGFKL_00229 1.9e-128 adcB P ABC transporter (Permease
KOOEGFKL_00230 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KOOEGFKL_00231 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KOOEGFKL_00232 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
KOOEGFKL_00233 1.1e-244 ptsG 2.7.1.199, 2.7.1.208 G pts system
KOOEGFKL_00234 2.9e-64 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KOOEGFKL_00235 1.4e-83 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KOOEGFKL_00236 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
KOOEGFKL_00237 1.9e-127 yeeN K transcriptional regulatory protein
KOOEGFKL_00238 9.8e-50 yajC U protein transport
KOOEGFKL_00239 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOOEGFKL_00240 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KOOEGFKL_00241 9.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KOOEGFKL_00242 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOOEGFKL_00243 0.0 WQ51_06230 S ABC transporter substrate binding protein
KOOEGFKL_00244 5.2e-142 cmpC S abc transporter atp-binding protein
KOOEGFKL_00245 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOOEGFKL_00246 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOOEGFKL_00247 2.1e-45 L transposase activity
KOOEGFKL_00248 1.2e-09 L Transposase
KOOEGFKL_00249 5.6e-50 L transposition
KOOEGFKL_00250 1.8e-33 L Integrase core domain protein
KOOEGFKL_00253 4e-42
KOOEGFKL_00254 3.4e-55 S TM2 domain
KOOEGFKL_00255 4.7e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOOEGFKL_00256 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOOEGFKL_00257 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOOEGFKL_00258 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
KOOEGFKL_00259 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KOOEGFKL_00260 1e-84 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KOOEGFKL_00261 2e-55 cof Q phosphatase activity
KOOEGFKL_00262 1.1e-34 cof Q phosphatase activity
KOOEGFKL_00263 9e-136 glcR K transcriptional regulator (DeoR family)
KOOEGFKL_00264 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOOEGFKL_00265 7.6e-41 K transcriptional
KOOEGFKL_00266 1.4e-87 S thiolester hydrolase activity
KOOEGFKL_00267 3e-139 S COG1073 Hydrolases of the alpha beta superfamily
KOOEGFKL_00268 2.8e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOOEGFKL_00269 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KOOEGFKL_00270 5.5e-77 yhaI L Membrane
KOOEGFKL_00271 6e-260 pepC 3.4.22.40 E aminopeptidase
KOOEGFKL_00272 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOOEGFKL_00273 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KOOEGFKL_00274 3.1e-95 ypsA S Belongs to the UPF0398 family
KOOEGFKL_00275 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KOOEGFKL_00276 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KOOEGFKL_00277 4.2e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KOOEGFKL_00278 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KOOEGFKL_00279 9.6e-23
KOOEGFKL_00280 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KOOEGFKL_00281 2.1e-21 XK27_09675 K -acetyltransferase
KOOEGFKL_00282 6.4e-47 XK27_09675 K -acetyltransferase
KOOEGFKL_00283 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOOEGFKL_00284 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOOEGFKL_00286 4.3e-80 L Integrase core domain protein
KOOEGFKL_00287 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOOEGFKL_00288 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KOOEGFKL_00289 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOOEGFKL_00290 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KOOEGFKL_00291 8.8e-98 ybhL S Belongs to the BI1 family
KOOEGFKL_00294 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOOEGFKL_00295 6.9e-90 K transcriptional regulator
KOOEGFKL_00296 7.6e-36 yneF S UPF0154 protein
KOOEGFKL_00297 2.4e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOOEGFKL_00298 3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOOEGFKL_00299 3.5e-99 XK27_09740 S Phosphoesterase
KOOEGFKL_00300 4.1e-86 ykuL S CBS domain
KOOEGFKL_00301 7.5e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KOOEGFKL_00302 2e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOOEGFKL_00303 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOOEGFKL_00304 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOOEGFKL_00305 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KOOEGFKL_00306 1.2e-258 trkH P Cation transport protein
KOOEGFKL_00307 1.5e-247 trkA P Potassium transporter peripheral membrane component
KOOEGFKL_00308 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOOEGFKL_00309 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOOEGFKL_00310 3.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KOOEGFKL_00311 5.6e-161 K sequence-specific DNA binding
KOOEGFKL_00312 7.2e-33 V protein secretion by the type I secretion system
KOOEGFKL_00313 3.1e-108 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOOEGFKL_00314 1.8e-54 comA V protein secretion by the type I secretion system
KOOEGFKL_00315 2.6e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOOEGFKL_00316 1.9e-21 yhaI L Membrane
KOOEGFKL_00317 6.8e-36 S Domain of unknown function (DUF4173)
KOOEGFKL_00318 1.4e-46 S Domain of unknown function (DUF4173)
KOOEGFKL_00319 4.9e-55 S Domain of unknown function (DUF4173)
KOOEGFKL_00320 1.2e-94 ureI S AmiS/UreI family transporter
KOOEGFKL_00321 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KOOEGFKL_00322 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KOOEGFKL_00323 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KOOEGFKL_00324 6.6e-78 ureE O enzyme active site formation
KOOEGFKL_00325 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KOOEGFKL_00326 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KOOEGFKL_00327 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KOOEGFKL_00328 7.9e-177 cbiM P PDGLE domain
KOOEGFKL_00329 1.7e-137 P cobalt transport protein
KOOEGFKL_00330 1.6e-131 cbiO P ABC transporter
KOOEGFKL_00331 3.4e-152 ET amino acid transport
KOOEGFKL_00332 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOOEGFKL_00333 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KOOEGFKL_00334 3.8e-205 EGP Transmembrane secretion effector
KOOEGFKL_00335 2e-152 ET amino acid transport
KOOEGFKL_00336 4.9e-165 metQ M Belongs to the NlpA lipoprotein family
KOOEGFKL_00337 5.5e-77 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KOOEGFKL_00338 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KOOEGFKL_00339 3.8e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KOOEGFKL_00340 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOOEGFKL_00341 3e-98 metI P ABC transporter (Permease
KOOEGFKL_00342 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KOOEGFKL_00343 1.3e-93 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KOOEGFKL_00344 1.2e-26 P Psort location CytoplasmicMembrane, score
KOOEGFKL_00345 1.2e-36 P Psort location CytoplasmicMembrane, score
KOOEGFKL_00346 2.2e-279 ykoD P abc transporter atp-binding protein
KOOEGFKL_00347 2.7e-146 cbiQ P cobalt transport
KOOEGFKL_00348 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOOEGFKL_00349 1.5e-10 ulaG S L-ascorbate 6-phosphate lactonase
KOOEGFKL_00350 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KOOEGFKL_00351 2.6e-242 P COG0168 Trk-type K transport systems, membrane components
KOOEGFKL_00352 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KOOEGFKL_00353 4.7e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KOOEGFKL_00354 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOEGFKL_00355 2.8e-282 T PhoQ Sensor
KOOEGFKL_00356 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOOEGFKL_00357 5e-218 dnaB L Replication initiation and membrane attachment
KOOEGFKL_00358 4e-167 dnaI L Primosomal protein DnaI
KOOEGFKL_00359 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KOOEGFKL_00360 3.1e-96
KOOEGFKL_00361 4e-56 S ABC-2 type transporter
KOOEGFKL_00362 2.2e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
KOOEGFKL_00363 1.4e-53 L Transposase
KOOEGFKL_00364 1.2e-146 L Transposase
KOOEGFKL_00366 6e-74 S Protein of unknown function DUF262
KOOEGFKL_00367 1.2e-82 S Protein of unknown function DUF262
KOOEGFKL_00368 1.3e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOOEGFKL_00369 6.5e-63 manO S protein conserved in bacteria
KOOEGFKL_00370 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
KOOEGFKL_00371 7.8e-117 manM G pts system
KOOEGFKL_00372 1.1e-181 manL 2.7.1.191 G pts system
KOOEGFKL_00373 3.4e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KOOEGFKL_00374 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KOOEGFKL_00375 1.2e-247 pbuO S permease
KOOEGFKL_00376 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KOOEGFKL_00377 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KOOEGFKL_00378 9.5e-220 brpA K Transcriptional
KOOEGFKL_00379 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KOOEGFKL_00380 3.1e-212 nusA K Participates in both transcription termination and antitermination
KOOEGFKL_00381 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KOOEGFKL_00382 1.4e-41 ylxQ J ribosomal protein
KOOEGFKL_00383 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOOEGFKL_00384 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOOEGFKL_00385 2e-09 yvdD 3.2.2.10 S Belongs to the LOG family
KOOEGFKL_00386 8.2e-21 yvdD 3.2.2.10 S cytokinin biosynthetic process
KOOEGFKL_00387 2.2e-24 yvdD 3.2.2.10 S cytokinin biosynthetic process
KOOEGFKL_00388 4.5e-233 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KOOEGFKL_00389 1.9e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOOEGFKL_00390 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KOOEGFKL_00391 1.9e-77 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KOOEGFKL_00392 7.9e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KOOEGFKL_00393 9.6e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KOOEGFKL_00394 1.4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KOOEGFKL_00395 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOOEGFKL_00396 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOOEGFKL_00397 3.7e-73 ylbF S Belongs to the UPF0342 family
KOOEGFKL_00398 7.1e-46 ylbG S UPF0298 protein
KOOEGFKL_00399 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KOOEGFKL_00400 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KOOEGFKL_00401 1.8e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KOOEGFKL_00402 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KOOEGFKL_00403 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KOOEGFKL_00404 9.5e-71 acuB S IMP dehydrogenase activity
KOOEGFKL_00405 3.3e-43 acuB S IMP dehydrogenase activity
KOOEGFKL_00406 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOOEGFKL_00407 1.4e-110 yvyE 3.4.13.9 S YigZ family
KOOEGFKL_00408 6.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KOOEGFKL_00409 3.4e-123 comFC S Competence protein
KOOEGFKL_00410 2.3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOOEGFKL_00418 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KOOEGFKL_00419 6.4e-108 S Domain of unknown function (DUF1803)
KOOEGFKL_00420 7.8e-102 ygaC J Belongs to the UPF0374 family
KOOEGFKL_00421 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KOOEGFKL_00422 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOOEGFKL_00423 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
KOOEGFKL_00424 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KOOEGFKL_00425 1.9e-115 S Haloacid dehalogenase-like hydrolase
KOOEGFKL_00426 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KOOEGFKL_00427 4e-72 marR K Transcriptional regulator, MarR family
KOOEGFKL_00428 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOOEGFKL_00429 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOOEGFKL_00430 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KOOEGFKL_00431 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KOOEGFKL_00432 1.3e-126 IQ reductase
KOOEGFKL_00433 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOOEGFKL_00434 9.4e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOOEGFKL_00435 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOOEGFKL_00436 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KOOEGFKL_00437 7.8e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOOEGFKL_00438 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KOOEGFKL_00439 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOOEGFKL_00440 1.3e-32 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KOOEGFKL_00441 5.2e-41 tnp L Transposase
KOOEGFKL_00442 3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KOOEGFKL_00443 4.4e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
KOOEGFKL_00444 4.7e-27 L Transposase and inactivated derivatives, TnpA family
KOOEGFKL_00445 2.8e-34 tnp L Transposase
KOOEGFKL_00446 7.3e-204 rny D Endoribonuclease that initiates mRNA decay
KOOEGFKL_00447 2e-83 L Transposase
KOOEGFKL_00448 2.3e-112 fruR K transcriptional
KOOEGFKL_00449 1.3e-162 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KOOEGFKL_00450 6.9e-114 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KOOEGFKL_00451 9.5e-140 fruA 2.7.1.202 G phosphotransferase system
KOOEGFKL_00452 8.6e-48 fruA 2.7.1.202 G phosphotransferase system
KOOEGFKL_00453 3.9e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOOEGFKL_00454 9e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOOEGFKL_00456 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KOOEGFKL_00457 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOOEGFKL_00458 2.7e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KOOEGFKL_00459 9.4e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KOOEGFKL_00460 2.9e-26 2.3.1.128 K acetyltransferase
KOOEGFKL_00461 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KOOEGFKL_00462 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KOOEGFKL_00463 1e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOOEGFKL_00464 2.6e-64 WQ51_03320 S cog cog4835
KOOEGFKL_00465 2.1e-43 XK27_08360 T EDD domain protein, DegV family
KOOEGFKL_00466 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOOEGFKL_00467 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KOOEGFKL_00468 0.0 yfmR S abc transporter atp-binding protein
KOOEGFKL_00469 1.6e-24 U response to pH
KOOEGFKL_00470 8e-137 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KOOEGFKL_00471 5e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KOOEGFKL_00472 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOOEGFKL_00473 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOOEGFKL_00474 1.9e-77 K DNA-binding transcription factor activity
KOOEGFKL_00475 0.0 lmrA1 V abc transporter atp-binding protein
KOOEGFKL_00476 0.0 lmrA2 V abc transporter atp-binding protein
KOOEGFKL_00477 1e-35 K Acetyltransferase (GNAT) family
KOOEGFKL_00478 9.8e-69 sptS 2.7.13.3 T Histidine kinase
KOOEGFKL_00479 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KOOEGFKL_00480 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOOEGFKL_00481 5.3e-161 cvfB S Protein conserved in bacteria
KOOEGFKL_00482 7.4e-35 yozE S Belongs to the UPF0346 family
KOOEGFKL_00483 1.2e-125 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
KOOEGFKL_00485 5.7e-60 rlpA M LysM domain protein
KOOEGFKL_00486 8e-191 phoH T phosphate starvation-inducible protein PhoH
KOOEGFKL_00490 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOOEGFKL_00491 3.4e-166 K transcriptional regulator (lysR family)
KOOEGFKL_00492 1.2e-185 coiA 3.6.4.12 S Competence protein
KOOEGFKL_00493 0.0 pepF E oligoendopeptidase F
KOOEGFKL_00494 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KOOEGFKL_00495 3.4e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KOOEGFKL_00496 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOOEGFKL_00497 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KOOEGFKL_00498 5e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KOOEGFKL_00499 1.8e-44 3.4.17.14, 3.5.1.28 NU amidase activity
KOOEGFKL_00500 7.7e-124 3.4.17.14, 3.5.1.28 NU amidase activity
KOOEGFKL_00501 6.9e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KOOEGFKL_00502 5.9e-227 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KOOEGFKL_00503 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOOEGFKL_00504 4e-223 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOOEGFKL_00505 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KOOEGFKL_00506 3.7e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KOOEGFKL_00507 4.6e-52 yxkH G deacetylase
KOOEGFKL_00508 1.7e-55 yxkH G deacetylase
KOOEGFKL_00510 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KOOEGFKL_00511 1.8e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOOEGFKL_00512 1e-151 rarD S Transporter
KOOEGFKL_00513 4.9e-15 T peptidase
KOOEGFKL_00514 8.9e-14 coiA 3.6.4.12 S Competence protein
KOOEGFKL_00515 9.4e-52 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KOOEGFKL_00516 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOOEGFKL_00517 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOOEGFKL_00518 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOOEGFKL_00519 1.8e-122 atpB C it plays a direct role in the translocation of protons across the membrane
KOOEGFKL_00520 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KOOEGFKL_00521 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOOEGFKL_00522 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOOEGFKL_00523 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOOEGFKL_00524 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOOEGFKL_00525 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KOOEGFKL_00526 8.1e-230 ftsW D Belongs to the SEDS family
KOOEGFKL_00527 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOOEGFKL_00528 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOOEGFKL_00529 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOOEGFKL_00530 6.4e-162 holB 2.7.7.7 L dna polymerase iii
KOOEGFKL_00531 1.4e-134 yaaT S stage 0 sporulation protein
KOOEGFKL_00532 9.5e-55 yabA L Involved in initiation control of chromosome replication
KOOEGFKL_00533 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOOEGFKL_00534 5.8e-233 amt P Ammonium Transporter
KOOEGFKL_00535 1.1e-53 glnB K Belongs to the P(II) protein family
KOOEGFKL_00536 4.9e-106 mur1 NU mannosyl-glycoprotein
KOOEGFKL_00537 1e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KOOEGFKL_00538 3.1e-115 nptA P COG1283 Na phosphate symporter
KOOEGFKL_00539 2.3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KOOEGFKL_00540 4e-53
KOOEGFKL_00541 3.7e-25
KOOEGFKL_00542 7.1e-62
KOOEGFKL_00543 1.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KOOEGFKL_00544 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KOOEGFKL_00545 4.5e-39 ynzC S UPF0291 protein
KOOEGFKL_00546 1.8e-254 cycA E permease
KOOEGFKL_00547 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
KOOEGFKL_00548 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KOOEGFKL_00549 5.8e-71 pts33BCA G pts system
KOOEGFKL_00550 9e-96 pts33BCA G pts system
KOOEGFKL_00551 2e-76 pts33BCA G pts system
KOOEGFKL_00552 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOOEGFKL_00557 1.4e-167 fhuR K transcriptional regulator (lysR family)
KOOEGFKL_00558 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOOEGFKL_00559 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOOEGFKL_00560 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOOEGFKL_00561 2.2e-227 pyrP F uracil Permease
KOOEGFKL_00562 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KOOEGFKL_00563 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KOOEGFKL_00564 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KOOEGFKL_00565 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
KOOEGFKL_00566 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOOEGFKL_00567 3e-42 V efflux transmembrane transporter activity
KOOEGFKL_00568 9.4e-24 V permease protein
KOOEGFKL_00569 0.0 L SNF2 family N-terminal domain
KOOEGFKL_00570 1.9e-65 S Domain of unknown function (DUF4391)
KOOEGFKL_00571 3.3e-235 mod 2.1.1.72 L DNA methylase
KOOEGFKL_00572 1.1e-57
KOOEGFKL_00573 0.0 res 3.1.21.5 L restriction endonuclease
KOOEGFKL_00574 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOOEGFKL_00575 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOOEGFKL_00577 0.0 mdlB V abc transporter atp-binding protein
KOOEGFKL_00578 0.0 lmrA V abc transporter atp-binding protein
KOOEGFKL_00579 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KOOEGFKL_00580 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOOEGFKL_00581 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KOOEGFKL_00582 2.5e-132 rr02 KT response regulator
KOOEGFKL_00583 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KOOEGFKL_00584 2.8e-168 V ABC transporter
KOOEGFKL_00585 5.4e-122 sagI S ABC-2 type transporter
KOOEGFKL_00586 1.5e-196 yceA S Belongs to the UPF0176 family
KOOEGFKL_00587 6.1e-28 XK27_00085 K Transcriptional
KOOEGFKL_00588 4.8e-19
KOOEGFKL_00589 1.5e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
KOOEGFKL_00590 7.3e-113 S VIT family
KOOEGFKL_00591 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOOEGFKL_00592 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KOOEGFKL_00593 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KOOEGFKL_00594 4e-44 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KOOEGFKL_00595 3e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOOEGFKL_00596 1.3e-102 GBS0088 J protein conserved in bacteria
KOOEGFKL_00597 3.3e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KOOEGFKL_00598 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KOOEGFKL_00599 6.2e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KOOEGFKL_00600 3.8e-190 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KOOEGFKL_00601 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOOEGFKL_00602 2.9e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KOOEGFKL_00603 2.5e-21
KOOEGFKL_00604 1.9e-116 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOOEGFKL_00606 3.5e-07 U protein secretion
KOOEGFKL_00607 9.6e-73 U protein secretion
KOOEGFKL_00608 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KOOEGFKL_00609 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KOOEGFKL_00610 4.9e-21 XK27_13030
KOOEGFKL_00611 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOOEGFKL_00612 3e-102 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOOEGFKL_00613 4.5e-58 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOOEGFKL_00614 8.9e-164 S Protein of unknown function (DUF3114)
KOOEGFKL_00615 4.6e-22 S Protein of unknown function (DUF3114)
KOOEGFKL_00616 1.5e-118 yqfA K protein, Hemolysin III
KOOEGFKL_00617 1e-25 K hmm pf08876
KOOEGFKL_00618 3.8e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KOOEGFKL_00619 1.7e-218 mvaS 2.3.3.10 I synthase
KOOEGFKL_00620 8.5e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOOEGFKL_00621 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KOOEGFKL_00622 1.3e-21
KOOEGFKL_00623 5.7e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOOEGFKL_00624 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KOOEGFKL_00625 1.7e-249 mmuP E amino acid
KOOEGFKL_00626 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KOOEGFKL_00627 1.4e-29 S Domain of unknown function (DUF1912)
KOOEGFKL_00628 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
KOOEGFKL_00629 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KOOEGFKL_00630 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOOEGFKL_00631 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOOEGFKL_00632 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KOOEGFKL_00633 4.8e-16 S Protein of unknown function (DUF2969)
KOOEGFKL_00636 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KOOEGFKL_00639 7.8e-30 S Domain of Unknown Function with PDB structure (DUF3862)
KOOEGFKL_00640 8.7e-31 S Domain of Unknown Function with PDB structure (DUF3862)
KOOEGFKL_00641 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
KOOEGFKL_00642 1.6e-08 S oxidoreductase
KOOEGFKL_00643 2.7e-65 S oxidoreductase
KOOEGFKL_00644 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
KOOEGFKL_00645 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KOOEGFKL_00646 0.0 clpE O Belongs to the ClpA ClpB family
KOOEGFKL_00647 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOOEGFKL_00648 1.3e-34 ykuJ S protein conserved in bacteria
KOOEGFKL_00649 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KOOEGFKL_00650 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_00651 3.1e-78 feoA P FeoA domain protein
KOOEGFKL_00652 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KOOEGFKL_00653 6.6e-08
KOOEGFKL_00654 1.5e-35 yugF I carboxylic ester hydrolase activity
KOOEGFKL_00655 1.5e-23 I Alpha/beta hydrolase family
KOOEGFKL_00656 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOOEGFKL_00657 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOOEGFKL_00658 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KOOEGFKL_00659 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOOEGFKL_00660 2.2e-63 licT K transcriptional antiterminator
KOOEGFKL_00661 6.8e-53 licT K transcriptional antiterminator
KOOEGFKL_00662 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOOEGFKL_00663 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KOOEGFKL_00664 4.9e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOOEGFKL_00665 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KOOEGFKL_00666 3.7e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOOEGFKL_00667 2.9e-221 mdtG EGP Major facilitator Superfamily
KOOEGFKL_00668 2e-33 secG U Preprotein translocase subunit SecG
KOOEGFKL_00669 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KOOEGFKL_00670 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOOEGFKL_00671 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOOEGFKL_00672 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KOOEGFKL_00673 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KOOEGFKL_00674 4.4e-183 ccpA K Catabolite control protein A
KOOEGFKL_00675 4.4e-26 yyaQ S YjbR
KOOEGFKL_00676 6.9e-144 yyaQ S YjbR
KOOEGFKL_00677 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KOOEGFKL_00678 1.3e-78 yueI S Protein of unknown function (DUF1694)
KOOEGFKL_00679 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOOEGFKL_00681 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOOEGFKL_00682 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
KOOEGFKL_00683 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KOOEGFKL_00684 2.8e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOOEGFKL_00685 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOOEGFKL_00686 2.2e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOOEGFKL_00687 5.9e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KOOEGFKL_00688 3.2e-53 yheA S Belongs to the UPF0342 family
KOOEGFKL_00689 1.5e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KOOEGFKL_00690 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOOEGFKL_00691 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KOOEGFKL_00692 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
KOOEGFKL_00693 9e-246 msrR K Transcriptional regulator
KOOEGFKL_00694 4.2e-92 ydiA P C4-dicarboxylate transporter malic acid transport
KOOEGFKL_00695 2.2e-201 I acyl-CoA dehydrogenase
KOOEGFKL_00696 2.7e-97 mip S hydroperoxide reductase activity
KOOEGFKL_00697 1.3e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOOEGFKL_00698 2.1e-106
KOOEGFKL_00699 1.3e-31 K Cro/C1-type HTH DNA-binding domain
KOOEGFKL_00700 6.7e-45 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KOOEGFKL_00701 7.3e-28 estA E GDSL-like Lipase/Acylhydrolase
KOOEGFKL_00702 4.8e-95
KOOEGFKL_00703 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KOOEGFKL_00704 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOOEGFKL_00705 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOOEGFKL_00706 6.9e-179 S CRISPR-associated protein Csn2 subfamily St
KOOEGFKL_00707 7.8e-146 ycgQ S TIGR03943 family
KOOEGFKL_00708 6.4e-157 XK27_03015 S permease
KOOEGFKL_00710 0.0 yhgF K Transcriptional accessory protein
KOOEGFKL_00711 4.9e-86 ydcK S Belongs to the SprT family
KOOEGFKL_00712 2.9e-41 pspC KT PspC domain
KOOEGFKL_00713 3.1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KOOEGFKL_00714 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOOEGFKL_00716 5.5e-69 ytxH S General stress protein
KOOEGFKL_00718 3e-178 yegQ O Peptidase U32
KOOEGFKL_00719 3.4e-252 yegQ O Peptidase U32
KOOEGFKL_00720 5.5e-87 bioY S biotin synthase
KOOEGFKL_00722 8.9e-33 XK27_12190 S protein conserved in bacteria
KOOEGFKL_00723 9.6e-234 mntH P H( )-stimulated, divalent metal cation uptake system
KOOEGFKL_00724 7.6e-09
KOOEGFKL_00725 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
KOOEGFKL_00726 0.0 L helicase
KOOEGFKL_00727 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KOOEGFKL_00728 5.1e-155 M LysM domain
KOOEGFKL_00729 1e-15
KOOEGFKL_00730 8.3e-173 S hydrolase
KOOEGFKL_00731 1.5e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KOOEGFKL_00732 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOOEGFKL_00733 2.1e-150 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KOOEGFKL_00734 3.1e-27 P Hemerythrin HHE cation binding domain protein
KOOEGFKL_00735 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOOEGFKL_00736 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
KOOEGFKL_00737 2.1e-23 MA20_36090 S Protein of unknown function (DUF2974)
KOOEGFKL_00738 9.5e-98 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOOEGFKL_00739 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KOOEGFKL_00740 3.4e-270 hsdM 2.1.1.72 V type I restriction-modification system
KOOEGFKL_00741 4.8e-152 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
KOOEGFKL_00742 3.2e-44
KOOEGFKL_00743 4.3e-37
KOOEGFKL_00744 4e-176 spd F DNA RNA non-specific endonuclease
KOOEGFKL_00745 3.4e-92 lemA S LemA family
KOOEGFKL_00746 1.9e-132 htpX O Belongs to the peptidase M48B family
KOOEGFKL_00747 4.2e-75 S Psort location CytoplasmicMembrane, score
KOOEGFKL_00748 6.2e-56 S Domain of unknown function (DUF4430)
KOOEGFKL_00749 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KOOEGFKL_00750 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KOOEGFKL_00751 2.5e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KOOEGFKL_00752 6.9e-195 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KOOEGFKL_00753 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KOOEGFKL_00754 1.6e-91 dps P Belongs to the Dps family
KOOEGFKL_00755 6.9e-80 perR P Belongs to the Fur family
KOOEGFKL_00756 8.4e-28 yqgQ S protein conserved in bacteria
KOOEGFKL_00757 2.2e-179 glk 2.7.1.2 G Glucokinase
KOOEGFKL_00758 0.0 typA T GTP-binding protein TypA
KOOEGFKL_00760 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOOEGFKL_00761 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOOEGFKL_00762 3.4e-176 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KOOEGFKL_00763 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KOOEGFKL_00764 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOOEGFKL_00765 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KOOEGFKL_00766 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOOEGFKL_00767 1.2e-34 yggT D integral membrane protein
KOOEGFKL_00768 7.2e-144 ylmH T S4 RNA-binding domain
KOOEGFKL_00769 7.9e-136 divIVA D Cell division protein DivIVA
KOOEGFKL_00770 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOOEGFKL_00771 2.1e-14
KOOEGFKL_00772 8.4e-10
KOOEGFKL_00773 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KOOEGFKL_00774 2e-45 rpmE2 J 50S ribosomal protein L31
KOOEGFKL_00775 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOOEGFKL_00776 2.3e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KOOEGFKL_00777 1.9e-143 gst O Glutathione S-transferase
KOOEGFKL_00778 7.9e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KOOEGFKL_00779 4.5e-111 tdk 2.7.1.21 F thymidine kinase
KOOEGFKL_00780 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOOEGFKL_00781 3e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOOEGFKL_00782 7.4e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KOOEGFKL_00783 2.6e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KOOEGFKL_00784 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KOOEGFKL_00785 4.1e-107 pvaA M lytic transglycosylase activity
KOOEGFKL_00786 0.0 yfiB1 V abc transporter atp-binding protein
KOOEGFKL_00787 0.0 XK27_10035 V abc transporter atp-binding protein
KOOEGFKL_00788 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KOOEGFKL_00789 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOOEGFKL_00790 1.1e-236 dltB M Membrane protein involved in D-alanine export
KOOEGFKL_00791 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOOEGFKL_00792 1e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KOOEGFKL_00793 3.5e-85 L Integrase core domain protein
KOOEGFKL_00794 7.2e-53 L transposition
KOOEGFKL_00795 1.2e-19 L transposase activity
KOOEGFKL_00796 0.0 3.6.3.8 P cation transport ATPase
KOOEGFKL_00797 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KOOEGFKL_00799 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOOEGFKL_00800 7.3e-166 metF 1.5.1.20 C reductase
KOOEGFKL_00801 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KOOEGFKL_00802 7.1e-93 panT S ECF transporter, substrate-specific component
KOOEGFKL_00803 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KOOEGFKL_00804 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KOOEGFKL_00805 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KOOEGFKL_00806 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOEGFKL_00807 1.1e-39 T PhoQ Sensor
KOOEGFKL_00808 1.7e-43 T PhoQ Sensor
KOOEGFKL_00809 3.3e-124 T PhoQ Sensor
KOOEGFKL_00810 3.9e-122 L Transposase
KOOEGFKL_00811 1.2e-165 L integrase core domain
KOOEGFKL_00812 2.1e-30 rpsT J rRNA binding
KOOEGFKL_00813 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KOOEGFKL_00814 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KOOEGFKL_00815 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KOOEGFKL_00816 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KOOEGFKL_00817 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KOOEGFKL_00818 1.8e-44 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KOOEGFKL_00819 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KOOEGFKL_00820 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KOOEGFKL_00821 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KOOEGFKL_00822 2.1e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KOOEGFKL_00823 4.1e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KOOEGFKL_00824 6.8e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
KOOEGFKL_00825 6.3e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KOOEGFKL_00826 2.6e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KOOEGFKL_00827 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KOOEGFKL_00828 6.8e-81 ypmB S Protein conserved in bacteria
KOOEGFKL_00829 1.9e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KOOEGFKL_00830 6.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KOOEGFKL_00831 2e-17
KOOEGFKL_00832 4.1e-110 L Transposase
KOOEGFKL_00833 3.3e-12
KOOEGFKL_00834 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KOOEGFKL_00835 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KOOEGFKL_00836 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KOOEGFKL_00837 8.4e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KOOEGFKL_00838 1.9e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KOOEGFKL_00839 4.5e-20 D nuclear chromosome segregation
KOOEGFKL_00840 2.8e-137 yejC S cyclic nucleotide-binding protein
KOOEGFKL_00841 1.2e-163 rapZ S Displays ATPase and GTPase activities
KOOEGFKL_00842 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KOOEGFKL_00843 8.7e-162 whiA K May be required for sporulation
KOOEGFKL_00844 1e-139 pepD E Dipeptidase
KOOEGFKL_00845 2.7e-31 cspD K Cold shock protein domain
KOOEGFKL_00846 9.4e-43 K Cold-Shock Protein
KOOEGFKL_00847 7.4e-50 L Transposase
KOOEGFKL_00848 2.6e-43 L Transposase
KOOEGFKL_00849 1.6e-109 L Transposase, Mutator family
KOOEGFKL_00850 0.0 copB 3.6.3.4 P P-type ATPase
KOOEGFKL_00851 1.4e-43 L Transposase
KOOEGFKL_00852 1.1e-44 L Transposase
KOOEGFKL_00853 2.5e-30 L Transposase
KOOEGFKL_00854 1.8e-53 L Transposase
KOOEGFKL_00855 4.2e-189 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KOOEGFKL_00856 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOOEGFKL_00857 1.3e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KOOEGFKL_00858 5.7e-98 cysE 2.3.1.30 E serine acetyltransferase
KOOEGFKL_00859 6.3e-54 L Transposase
KOOEGFKL_00860 4.1e-147 L Transposase
KOOEGFKL_00861 7.6e-47 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KOOEGFKL_00862 3e-113 hsdM 2.1.1.72 V type I restriction-modification system
KOOEGFKL_00863 2.8e-157 glcU U Glucose uptake
KOOEGFKL_00864 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
KOOEGFKL_00865 5e-78 hsdM 2.1.1.72 V HsdM N-terminal domain
KOOEGFKL_00866 1.4e-87 XK27_10720 D peptidase activity
KOOEGFKL_00867 3.3e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
KOOEGFKL_00868 1.7e-08
KOOEGFKL_00869 4.3e-170 yeiH S Membrane
KOOEGFKL_00870 1.7e-79 mur1 NU amidase activity
KOOEGFKL_00871 3.2e-83 L transposition
KOOEGFKL_00872 2.6e-166 cpsY K Transcriptional regulator
KOOEGFKL_00873 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOOEGFKL_00874 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KOOEGFKL_00875 2.4e-105 artQ P ABC transporter (Permease
KOOEGFKL_00876 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_00877 4.3e-158 aatB ET ABC transporter substrate-binding protein
KOOEGFKL_00878 2.5e-147 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOOEGFKL_00879 2.1e-07
KOOEGFKL_00880 3.3e-53 adhP 1.1.1.1 C alcohol dehydrogenase
KOOEGFKL_00881 1.2e-80 adhP 1.1.1.1 C alcohol dehydrogenase
KOOEGFKL_00882 7.4e-50 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KOOEGFKL_00883 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KOOEGFKL_00884 1.6e-126 gntR1 K transcriptional
KOOEGFKL_00885 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KOOEGFKL_00886 6.5e-258 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOOEGFKL_00887 2.4e-87 niaX
KOOEGFKL_00888 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
KOOEGFKL_00889 5.6e-129 K DNA-binding helix-turn-helix protein
KOOEGFKL_00890 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KOOEGFKL_00891 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOOEGFKL_00892 3.7e-168 GK ROK family
KOOEGFKL_00893 1.1e-158 dprA LU DNA protecting protein DprA
KOOEGFKL_00894 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOOEGFKL_00895 1.5e-152 S TraX protein
KOOEGFKL_00896 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOEGFKL_00897 3.9e-254 T PhoQ Sensor
KOOEGFKL_00898 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KOOEGFKL_00899 4.2e-152 XK27_05470 E Methionine synthase
KOOEGFKL_00900 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KOOEGFKL_00901 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOOEGFKL_00902 1.1e-46 IQ Acetoin reductase
KOOEGFKL_00903 9.1e-46 IQ Acetoin reductase
KOOEGFKL_00905 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOOEGFKL_00907 1.1e-53 K peptidyl-tyrosine sulfation
KOOEGFKL_00908 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KOOEGFKL_00911 1.1e-212 pqqE C radical SAM domain protein
KOOEGFKL_00912 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KOOEGFKL_00913 6.6e-61 EGP Major facilitator Superfamily
KOOEGFKL_00914 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KOOEGFKL_00915 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KOOEGFKL_00916 2.5e-86 L Transposase
KOOEGFKL_00917 4.2e-29 L Helix-turn-helix domain of transposase family ISL3
KOOEGFKL_00918 1.2e-51 L Transposase
KOOEGFKL_00919 1.4e-14 lytN 3.5.1.104 M LysM domain
KOOEGFKL_00920 3.5e-230 L Transposase
KOOEGFKL_00921 1.2e-116 V ABC transporter (Permease
KOOEGFKL_00922 6.6e-112 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOOEGFKL_00923 1.8e-10
KOOEGFKL_00924 1.2e-97 K Transcriptional regulator, TetR family
KOOEGFKL_00925 2.3e-159 czcD P cation diffusion facilitator family transporter
KOOEGFKL_00926 3.4e-192 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KOOEGFKL_00927 8.1e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KOOEGFKL_00929 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
KOOEGFKL_00930 8.5e-78 S Alpha/beta hydrolase of unknown function (DUF915)
KOOEGFKL_00933 2.6e-143 2.4.2.3 F Phosphorylase superfamily
KOOEGFKL_00934 3.9e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KOOEGFKL_00935 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
KOOEGFKL_00936 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KOOEGFKL_00937 3.2e-97 dinF V Mate efflux family protein
KOOEGFKL_00938 7.5e-29 dinF V Mate efflux family protein
KOOEGFKL_00939 6.5e-266 S Psort location CytoplasmicMembrane, score
KOOEGFKL_00940 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KOOEGFKL_00942 1.7e-112 S TraX protein
KOOEGFKL_00943 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KOOEGFKL_00944 2.2e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KOOEGFKL_00945 1e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOOEGFKL_00946 4.9e-182 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOOEGFKL_00947 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOOEGFKL_00948 3.1e-69 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOOEGFKL_00949 1.3e-57 mesE M HlyD family secretion protein
KOOEGFKL_00950 3.1e-69 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOOEGFKL_00951 3.2e-216 mesE M HlyD family secretion protein
KOOEGFKL_00952 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOOEGFKL_00956 2.6e-46 S Enterocin A Immunity
KOOEGFKL_00957 3.1e-10 blpU S hmm tigr01847
KOOEGFKL_00959 3.1e-16
KOOEGFKL_00960 1.2e-51
KOOEGFKL_00964 7.4e-09 S Bacteriocin class II with double-glycine leader peptide
KOOEGFKL_00965 6e-54
KOOEGFKL_00968 2.3e-134 blpT
KOOEGFKL_00969 2.2e-25
KOOEGFKL_00970 1.2e-132 agrA KT phosphorelay signal transduction system
KOOEGFKL_00971 2e-138 2.7.13.3 T protein histidine kinase activity
KOOEGFKL_00974 1.8e-51 csm6 S Psort location Cytoplasmic, score
KOOEGFKL_00975 2.5e-146 csm6 S Psort location Cytoplasmic, score
KOOEGFKL_00976 3.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KOOEGFKL_00977 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOOEGFKL_00978 5e-65 nylA 3.5.1.4 J Belongs to the amidase family
KOOEGFKL_00979 1.8e-265 dtpT E transporter
KOOEGFKL_00980 4.3e-104 nylA 3.5.1.4 J Belongs to the amidase family
KOOEGFKL_00981 1.9e-71 yckB ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_00982 9.7e-23 yckB ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_00983 8.5e-28 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_00984 9.2e-22 yecS P amino acid transport
KOOEGFKL_00986 4e-273 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KOOEGFKL_00987 7.3e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KOOEGFKL_00988 3.4e-32 yfiF3 K sequence-specific DNA binding
KOOEGFKL_00989 1e-22 bglC K Transcriptional regulator
KOOEGFKL_00990 2e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KOOEGFKL_00991 3.4e-239 agcS E (Alanine) symporter
KOOEGFKL_00992 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KOOEGFKL_00993 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
KOOEGFKL_00994 5.8e-58 Q phosphatase activity
KOOEGFKL_00995 9.3e-62 S haloacid dehalogenase-like hydrolase
KOOEGFKL_00996 6.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KOOEGFKL_00997 5.3e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KOOEGFKL_00998 4.7e-108 XK27_04775 S hemerythrin HHE cation binding domain
KOOEGFKL_00999 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
KOOEGFKL_01000 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOOEGFKL_01001 3.5e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KOOEGFKL_01002 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KOOEGFKL_01003 1.9e-43 yktA S Belongs to the UPF0223 family
KOOEGFKL_01004 1.9e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KOOEGFKL_01005 4e-101 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KOOEGFKL_01006 7.8e-131 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KOOEGFKL_01007 4.3e-158 pstS P phosphate
KOOEGFKL_01008 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KOOEGFKL_01009 1.2e-155 pstA P phosphate transport system permease
KOOEGFKL_01010 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOOEGFKL_01011 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOOEGFKL_01012 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KOOEGFKL_01013 0.0 pepN 3.4.11.2 E aminopeptidase
KOOEGFKL_01014 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KOOEGFKL_01016 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KOOEGFKL_01019 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOOEGFKL_01020 7.6e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KOOEGFKL_01021 6.2e-177 malR K Transcriptional regulator
KOOEGFKL_01022 2e-19 malX G ABC transporter
KOOEGFKL_01023 2.9e-12 malX G maltose binding
KOOEGFKL_01024 1e-63 malX G maltose binding
KOOEGFKL_01025 1.2e-110 malF P ABC transporter (Permease
KOOEGFKL_01026 4.6e-25 tatA U protein secretion
KOOEGFKL_01027 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KOOEGFKL_01028 4.8e-299 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KOOEGFKL_01029 1.5e-233 ycdB P peroxidase
KOOEGFKL_01030 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
KOOEGFKL_01031 7.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
KOOEGFKL_01032 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
KOOEGFKL_01033 1.6e-166 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOOEGFKL_01034 3.4e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOOEGFKL_01035 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KOOEGFKL_01036 2.4e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KOOEGFKL_01037 7.9e-238 L Transposase
KOOEGFKL_01038 2.2e-181 EGP Transmembrane secretion effector
KOOEGFKL_01039 1.6e-94 6.3.2.2, 6.3.2.4 M ATP-grasp domain
KOOEGFKL_01040 5.5e-120 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOOEGFKL_01043 1.2e-100 L nUDIX hydrolase
KOOEGFKL_01044 3.2e-172 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOOEGFKL_01045 6.7e-156 K Transcriptional activator, Rgg GadR MutR family
KOOEGFKL_01046 1e-237 L Transposase
KOOEGFKL_01047 3.5e-76 3.5.1.28 NU amidase activity
KOOEGFKL_01048 0.0 lpdA 1.8.1.4 C Dehydrogenase
KOOEGFKL_01049 3.5e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOOEGFKL_01050 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KOOEGFKL_01051 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KOOEGFKL_01052 4.3e-100 hpk9 2.7.13.3 T protein histidine kinase activity
KOOEGFKL_01053 8.6e-10 2.7.13.3 T protein histidine kinase activity
KOOEGFKL_01054 1.2e-52 2.7.13.3 T protein histidine kinase activity
KOOEGFKL_01055 5.6e-161 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
KOOEGFKL_01056 5.5e-167 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOOEGFKL_01057 3.2e-110 casE S CRISPR system CASCADE complex protein CasE
KOOEGFKL_01058 3.6e-134 casD S CRISPR system CASCADE complex protein CasD
KOOEGFKL_01059 6.8e-182 casC L CT1975-like protein
KOOEGFKL_01060 2.7e-103 casB S CRISPR system CASCADE complex protein CasB
KOOEGFKL_01061 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01062 0.0 cas3 L CRISPR-associated helicase cas3
KOOEGFKL_01063 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01064 4.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOOEGFKL_01065 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOOEGFKL_01066 1.4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOOEGFKL_01067 1.4e-158 rssA S Phospholipase, patatin family
KOOEGFKL_01068 5.6e-98 estA E Lysophospholipase L1 and related esterases
KOOEGFKL_01069 2.9e-290 S unusual protein kinase
KOOEGFKL_01070 7e-38 S granule-associated protein
KOOEGFKL_01071 2.2e-28 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOOEGFKL_01072 3.2e-42 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KOOEGFKL_01073 3.3e-100 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOOEGFKL_01074 7.7e-200 S hmm pf01594
KOOEGFKL_01075 6.9e-43 G alpha-ribazole phosphatase activity
KOOEGFKL_01076 1.4e-68 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KOOEGFKL_01077 2.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KOOEGFKL_01079 2.2e-64 GT2,GT4 M Glycosyltransferase GT-D fold
KOOEGFKL_01080 6.4e-33 cpsJ S Glycosyltransferase like family 2
KOOEGFKL_01081 6.6e-15
KOOEGFKL_01082 8.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
KOOEGFKL_01083 7.3e-41 pssE S Glycosyltransferase family 28 C-terminal domain
KOOEGFKL_01084 1.1e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KOOEGFKL_01085 3.1e-47 rfbP 2.7.8.6 M Bacterial sugar transferase
KOOEGFKL_01086 1.5e-33 L transposase activity
KOOEGFKL_01087 5.2e-73 L transposition
KOOEGFKL_01088 2.3e-22 tnp L DDE domain
KOOEGFKL_01089 2.3e-241 cps1C S Polysaccharide biosynthesis protein
KOOEGFKL_01090 8.5e-224 L Transposase
KOOEGFKL_01091 5.7e-98 2.7.8.12 GT2 S Glycosyltransferase like family 2
KOOEGFKL_01092 6.9e-40 L Integrase core domain
KOOEGFKL_01093 1.6e-82 L Integrase core domain
KOOEGFKL_01094 1e-15 L Transposase
KOOEGFKL_01095 5.5e-124 tnp L DDE domain
KOOEGFKL_01096 6.9e-25 rgpAc GT4 M group 1 family protein
KOOEGFKL_01097 5.5e-253 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KOOEGFKL_01098 3.2e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
KOOEGFKL_01099 1.2e-94 cps4C M biosynthesis protein
KOOEGFKL_01100 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KOOEGFKL_01101 1.1e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KOOEGFKL_01102 4.5e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KOOEGFKL_01103 6e-126 yfeJ 6.3.5.2 F glutamine amidotransferase
KOOEGFKL_01104 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KOOEGFKL_01105 7.3e-63 S Protein of unknown function (DUF1697)
KOOEGFKL_01106 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KOOEGFKL_01107 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOOEGFKL_01109 3.7e-07 V Glucan-binding protein C
KOOEGFKL_01110 6.1e-22 V Glucan-binding protein C
KOOEGFKL_01111 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
KOOEGFKL_01112 8.2e-276 pepV 3.5.1.18 E Dipeptidase
KOOEGFKL_01113 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KOOEGFKL_01114 1.1e-46 XK27_03610 K Gnat family
KOOEGFKL_01115 1.6e-24 L Transposase
KOOEGFKL_01116 5.8e-42 L Transposase
KOOEGFKL_01117 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOOEGFKL_01118 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KOOEGFKL_01119 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOOEGFKL_01120 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KOOEGFKL_01121 1e-15 M LysM domain
KOOEGFKL_01122 1.2e-88 ebsA S Family of unknown function (DUF5322)
KOOEGFKL_01123 3.3e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KOOEGFKL_01124 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KOOEGFKL_01125 3.1e-223 G COG0457 FOG TPR repeat
KOOEGFKL_01126 6.2e-176 yubA S permease
KOOEGFKL_01127 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KOOEGFKL_01128 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KOOEGFKL_01129 5.5e-124 ftsE D cell division ATP-binding protein FtsE
KOOEGFKL_01130 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOOEGFKL_01131 2.3e-207 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KOOEGFKL_01132 1.7e-164 yjjH S Calcineurin-like phosphoesterase
KOOEGFKL_01133 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KOOEGFKL_01134 0.0 pacL 3.6.3.8 P cation transport ATPase
KOOEGFKL_01135 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KOOEGFKL_01136 9.2e-147 yidA S hydrolases of the HAD superfamily
KOOEGFKL_01137 2.6e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KOOEGFKL_01138 1.5e-34 F Protein of unknown function (DUF454)
KOOEGFKL_01139 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KOOEGFKL_01140 3.9e-235 vicK 2.7.13.3 T Histidine kinase
KOOEGFKL_01141 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOEGFKL_01142 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_01143 1.4e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KOOEGFKL_01144 3.8e-117 gltJ P ABC transporter (Permease
KOOEGFKL_01145 1.7e-111 tcyB_2 P ABC transporter (permease)
KOOEGFKL_01146 2.4e-124 endA F DNA RNA non-specific endonuclease
KOOEGFKL_01147 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KOOEGFKL_01148 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOOEGFKL_01150 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOOEGFKL_01151 1.7e-25 G Domain of unknown function (DUF4832)
KOOEGFKL_01152 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOOEGFKL_01153 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOOEGFKL_01154 2.1e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOOEGFKL_01155 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KOOEGFKL_01156 1.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOOEGFKL_01157 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KOOEGFKL_01160 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOOEGFKL_01161 3e-218 XK27_05110 P chloride
KOOEGFKL_01162 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KOOEGFKL_01163 9.2e-281 clcA P Chloride transporter, ClC family
KOOEGFKL_01164 1.1e-74 fld C Flavodoxin
KOOEGFKL_01165 3.3e-14 XK27_08880
KOOEGFKL_01166 1.8e-125 XK27_08875 O Zinc-dependent metalloprotease
KOOEGFKL_01167 1.6e-151 estA CE1 S Putative esterase
KOOEGFKL_01168 4.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOOEGFKL_01169 5.8e-135 XK27_08845 S abc transporter atp-binding protein
KOOEGFKL_01170 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KOOEGFKL_01171 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
KOOEGFKL_01172 3.2e-17 S Domain of unknown function (DUF4649)
KOOEGFKL_01173 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01174 5.4e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01176 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01177 1.4e-53 L Transposase
KOOEGFKL_01178 2e-149 L Transposase
KOOEGFKL_01180 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KOOEGFKL_01181 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KOOEGFKL_01182 0.0 dnaE 2.7.7.7 L DNA polymerase
KOOEGFKL_01183 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KOOEGFKL_01184 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOOEGFKL_01185 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOOEGFKL_01186 1.3e-42 ysdA L Membrane
KOOEGFKL_01187 5.6e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOOEGFKL_01188 3.8e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KOOEGFKL_01189 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOOEGFKL_01190 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KOOEGFKL_01192 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOOEGFKL_01193 2.6e-95 ypmS S Protein conserved in bacteria
KOOEGFKL_01194 1.6e-144 ypmR E lipolytic protein G-D-S-L family
KOOEGFKL_01195 1.7e-148 DegV S DegV family
KOOEGFKL_01196 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KOOEGFKL_01197 1.1e-72 argR K arginine binding
KOOEGFKL_01198 5.6e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KOOEGFKL_01199 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOOEGFKL_01200 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KOOEGFKL_01201 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOOEGFKL_01204 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOOEGFKL_01205 1.1e-124 dnaD
KOOEGFKL_01206 2.7e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KOOEGFKL_01207 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOOEGFKL_01208 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KOOEGFKL_01209 1.1e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOOEGFKL_01210 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KOOEGFKL_01211 7.9e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KOOEGFKL_01212 2.1e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOOEGFKL_01213 4.4e-237 rodA D Belongs to the SEDS family
KOOEGFKL_01214 2.4e-90 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KOOEGFKL_01215 3.9e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KOOEGFKL_01216 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KOOEGFKL_01217 9e-121 ylfI S tigr01906
KOOEGFKL_01218 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KOOEGFKL_01219 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
KOOEGFKL_01220 2.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KOOEGFKL_01224 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOOEGFKL_01225 3.2e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KOOEGFKL_01226 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOOEGFKL_01227 1.3e-207 yurR 1.4.5.1 E oxidoreductase
KOOEGFKL_01228 7.4e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
KOOEGFKL_01229 2.4e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
KOOEGFKL_01230 4.8e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KOOEGFKL_01231 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KOOEGFKL_01232 2.2e-70 gtrA S GtrA-like protein
KOOEGFKL_01233 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOOEGFKL_01234 3.3e-167 ybbR S Protein conserved in bacteria
KOOEGFKL_01235 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOOEGFKL_01236 4.9e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KOOEGFKL_01237 7.3e-149 cobQ S glutamine amidotransferase
KOOEGFKL_01238 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOOEGFKL_01239 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KOOEGFKL_01241 0.0 uup S abc transporter atp-binding protein
KOOEGFKL_01242 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KOOEGFKL_01243 3.3e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
KOOEGFKL_01244 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOOEGFKL_01245 1.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KOOEGFKL_01246 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOOEGFKL_01247 7.9e-39 ptsH G phosphocarrier protein Hpr
KOOEGFKL_01248 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
KOOEGFKL_01249 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
KOOEGFKL_01250 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KOOEGFKL_01251 2.2e-34 nrdH O Glutaredoxin
KOOEGFKL_01252 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOOEGFKL_01253 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOOEGFKL_01255 4.7e-70 L Transposase (IS116 IS110 IS902 family)
KOOEGFKL_01256 1.2e-52 L Transposase (IS116 IS110 IS902 family)
KOOEGFKL_01257 1.5e-164 ypuA S secreted protein
KOOEGFKL_01258 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
KOOEGFKL_01259 5.6e-130 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KOOEGFKL_01260 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOOEGFKL_01261 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KOOEGFKL_01262 2.8e-257 noxE P NADH oxidase
KOOEGFKL_01263 2.5e-294 yfmM S abc transporter atp-binding protein
KOOEGFKL_01264 3.6e-83 XK27_01265 S ECF-type riboflavin transporter, S component
KOOEGFKL_01265 3.9e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KOOEGFKL_01266 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KOOEGFKL_01267 5.7e-86 S ECF-type riboflavin transporter, S component
KOOEGFKL_01269 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOOEGFKL_01270 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KOOEGFKL_01273 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOOEGFKL_01274 3.3e-89 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOOEGFKL_01275 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOOEGFKL_01276 0.0 smc D Required for chromosome condensation and partitioning
KOOEGFKL_01277 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOOEGFKL_01278 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOOEGFKL_01279 3.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOOEGFKL_01280 8.5e-89 alkD L Dna alkylation repair
KOOEGFKL_01281 2.4e-92 pat 2.3.1.183 M acetyltransferase
KOOEGFKL_01282 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOOEGFKL_01283 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOOEGFKL_01284 3.7e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KOOEGFKL_01285 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
KOOEGFKL_01286 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
KOOEGFKL_01287 3.3e-26
KOOEGFKL_01288 1.1e-92 S ABC-2 family transporter protein
KOOEGFKL_01289 2.2e-07 S ABC-2 family transporter protein
KOOEGFKL_01290 6.6e-99 S transport system, permease component
KOOEGFKL_01291 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOOEGFKL_01292 1.5e-192 desK 2.7.13.3 T Histidine kinase
KOOEGFKL_01293 1.1e-133 yvfS V ABC-2 type transporter
KOOEGFKL_01294 3.2e-119 XK27_09825 V abc transporter atp-binding protein
KOOEGFKL_01297 1.5e-156 yocS S Transporter
KOOEGFKL_01298 4.4e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KOOEGFKL_01299 4.7e-22 P ABC transporter transmembrane region
KOOEGFKL_01300 4.1e-34 M translation initiation factor activity
KOOEGFKL_01301 6.2e-17
KOOEGFKL_01302 1.6e-60
KOOEGFKL_01303 8.9e-67 MA20_25245 K Acetyltransferase (GNAT) family
KOOEGFKL_01304 4.8e-46 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOOEGFKL_01305 2.8e-64 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOOEGFKL_01306 4.3e-74 XK27_01300 P Protein conserved in bacteria
KOOEGFKL_01307 3.9e-08
KOOEGFKL_01308 9.5e-212 EGP Major facilitator Superfamily
KOOEGFKL_01309 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KOOEGFKL_01310 8.7e-151 mutR K Transcriptional activator, Rgg GadR MutR family
KOOEGFKL_01311 4.4e-49 3.6.1.55 F NUDIX domain
KOOEGFKL_01313 3.7e-122 S An automated process has identified a potential problem with this gene model
KOOEGFKL_01314 1.2e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KOOEGFKL_01315 2.4e-15 liaI KT membrane
KOOEGFKL_01316 4.4e-30 liaI KT membrane
KOOEGFKL_01317 1.4e-92 XK27_05000 S Fe-S-cluster oxidoreductase
KOOEGFKL_01318 0.0 V ABC transporter (permease)
KOOEGFKL_01319 1.9e-133 macB2 V ABC transporter, ATP-binding protein
KOOEGFKL_01320 3.1e-165 T Histidine kinase
KOOEGFKL_01321 9.2e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOEGFKL_01322 7.8e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOOEGFKL_01323 1.8e-16 pbuX F xanthine permease
KOOEGFKL_01324 9.4e-57 pbuX F xanthine permease
KOOEGFKL_01325 1.9e-66 pbuX F xanthine permease
KOOEGFKL_01326 6e-36 pbuX F xanthine permease
KOOEGFKL_01327 5.9e-247 norM V Multidrug efflux pump
KOOEGFKL_01328 2.6e-185 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOOEGFKL_01329 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_01330 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
KOOEGFKL_01331 1.2e-92 yxeO 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_01332 4.1e-63 yxeN U ABC transporter, permease protein
KOOEGFKL_01333 1.9e-58 yxeL K Acetyltransferase (GNAT) domain
KOOEGFKL_01334 3e-115 yxeQ S MmgE/PrpD family
KOOEGFKL_01335 2.4e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KOOEGFKL_01336 6.7e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KOOEGFKL_01337 3.4e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KOOEGFKL_01338 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KOOEGFKL_01339 6.6e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KOOEGFKL_01340 5.6e-234 brnQ E Component of the transport system for branched-chain amino acids
KOOEGFKL_01341 3.2e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOOEGFKL_01342 5.7e-58 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOOEGFKL_01343 9.6e-26 csbD K CsbD-like
KOOEGFKL_01345 3.1e-227 yfnA E amino acid
KOOEGFKL_01346 9.7e-109 XK27_02070 S nitroreductase
KOOEGFKL_01347 4.7e-140 1.13.11.2 S glyoxalase
KOOEGFKL_01348 2.1e-76 ywnA K Transcriptional regulator
KOOEGFKL_01349 1e-156 E Alpha/beta hydrolase of unknown function (DUF915)
KOOEGFKL_01350 4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOOEGFKL_01351 1.3e-111 drgA C Nitroreductase
KOOEGFKL_01352 6.5e-10 yoaK S Protein of unknown function (DUF1275)
KOOEGFKL_01353 1.4e-68 yoaK S Protein of unknown function (DUF1275)
KOOEGFKL_01355 3.1e-161 yvgN C reductase
KOOEGFKL_01356 3e-101 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOOEGFKL_01357 6.9e-09
KOOEGFKL_01358 3.1e-115 S Abortive infection C-terminus
KOOEGFKL_01359 0.0 L DEAD-like helicases superfamily
KOOEGFKL_01360 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KOOEGFKL_01361 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
KOOEGFKL_01363 6.7e-38 BP1961 P nitric oxide dioxygenase activity
KOOEGFKL_01364 2.4e-54 K response regulator
KOOEGFKL_01365 1e-70 S Signal peptide protein, YSIRK family
KOOEGFKL_01367 6.1e-58
KOOEGFKL_01368 2.4e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOOEGFKL_01369 5.2e-106
KOOEGFKL_01370 3.7e-10 IQ PFAM AMP-dependent synthetase and ligase
KOOEGFKL_01371 1.5e-07 IQ PFAM AMP-dependent synthetase and ligase
KOOEGFKL_01372 2.2e-108 MA20_06410 E LysE type translocator
KOOEGFKL_01373 5.6e-08
KOOEGFKL_01374 7.9e-09
KOOEGFKL_01376 0.0 M family 8
KOOEGFKL_01377 1.2e-51 L Transposase
KOOEGFKL_01378 4.2e-29 L Helix-turn-helix domain of transposase family ISL3
KOOEGFKL_01379 7.9e-88 L Transposase
KOOEGFKL_01380 5.1e-21 L overlaps another CDS with the same product name
KOOEGFKL_01381 1.7e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
KOOEGFKL_01382 8.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOOEGFKL_01383 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
KOOEGFKL_01384 2.6e-152 S metal-dependent hydrolase with the TIM-barrel fold
KOOEGFKL_01385 7.7e-123 dlpA H Methyltransferase
KOOEGFKL_01386 4e-209 dlpA 1.1.1.85 CE Tartrate dehydrogenase
KOOEGFKL_01388 9.8e-161 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
KOOEGFKL_01389 4.4e-18
KOOEGFKL_01391 6.7e-40 L transposition
KOOEGFKL_01392 1.5e-21 L Transposase and inactivated derivatives
KOOEGFKL_01393 2.7e-44 L Transposase and inactivated derivatives
KOOEGFKL_01394 2.6e-43 L COG2963 Transposase and inactivated derivatives
KOOEGFKL_01395 3.8e-20
KOOEGFKL_01396 0.0 sbcC L ATPase involved in DNA repair
KOOEGFKL_01397 2e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KOOEGFKL_01398 2.7e-182 L Transposase and inactivated derivatives IS30 family
KOOEGFKL_01399 0.0 lacL 3.2.1.23 G -beta-galactosidase
KOOEGFKL_01400 0.0 lacS G transporter
KOOEGFKL_01401 5.8e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KOOEGFKL_01402 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOOEGFKL_01403 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KOOEGFKL_01404 4e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KOOEGFKL_01405 6.8e-184 galR K Transcriptional regulator
KOOEGFKL_01406 7.1e-09 L Integrase core domain protein
KOOEGFKL_01407 1e-24 L transposition
KOOEGFKL_01408 3.1e-195 M translation initiation factor activity
KOOEGFKL_01409 1.8e-61 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KOOEGFKL_01410 6.5e-102 V abc transporter atp-binding protein
KOOEGFKL_01411 1e-41 V (ABC) transporter
KOOEGFKL_01412 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KOOEGFKL_01413 2.3e-87 L Transposase
KOOEGFKL_01414 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KOOEGFKL_01415 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KOOEGFKL_01416 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KOOEGFKL_01417 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOOEGFKL_01420 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOOEGFKL_01421 5.8e-175 vraS 2.7.13.3 T Histidine kinase
KOOEGFKL_01422 2.4e-119 yvqF KT membrane
KOOEGFKL_01423 1e-232 L Transposase
KOOEGFKL_01424 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KOOEGFKL_01425 2e-132 stp 3.1.3.16 T phosphatase
KOOEGFKL_01426 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KOOEGFKL_01427 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOOEGFKL_01428 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOOEGFKL_01429 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KOOEGFKL_01430 2.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KOOEGFKL_01431 3.7e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOOEGFKL_01432 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
KOOEGFKL_01433 9.1e-144 supH S overlaps another CDS with the same product name
KOOEGFKL_01434 8.6e-63 yvoA_1 K Transcriptional
KOOEGFKL_01435 1.1e-119 skfE V abc transporter atp-binding protein
KOOEGFKL_01436 2.8e-132 V ATPase activity
KOOEGFKL_01437 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KOOEGFKL_01438 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KOOEGFKL_01439 4.9e-168 amiD P ABC transporter (Permease
KOOEGFKL_01440 2.1e-277 amiC P ABC transporter (Permease
KOOEGFKL_01441 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KOOEGFKL_01442 2.7e-230 L Transposase
KOOEGFKL_01443 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KOOEGFKL_01444 1.2e-24 oppF P Belongs to the ABC transporter superfamily
KOOEGFKL_01445 2e-46 oppF P Belongs to the ABC transporter superfamily
KOOEGFKL_01446 2.3e-21 tatD L Hydrolase, tatd
KOOEGFKL_01447 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
KOOEGFKL_01448 2.1e-85 L PFAM Integrase catalytic region
KOOEGFKL_01449 5.3e-56 L transposition
KOOEGFKL_01450 4.3e-23 L transposase activity
KOOEGFKL_01451 1.5e-36 L transposase activity
KOOEGFKL_01452 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KOOEGFKL_01453 7e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KOOEGFKL_01454 3.2e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOOEGFKL_01455 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KOOEGFKL_01456 1.5e-103 yjbK S Adenylate cyclase
KOOEGFKL_01457 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOOEGFKL_01458 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
KOOEGFKL_01459 1e-57 XK27_04120 S Putative amino acid metabolism
KOOEGFKL_01460 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KOOEGFKL_01461 3.4e-73 puuD T peptidase C26
KOOEGFKL_01462 6.2e-24 puuD T peptidase C26
KOOEGFKL_01463 6.2e-120 radC E Belongs to the UPF0758 family
KOOEGFKL_01464 8.6e-268 M Psort location CytoplasmicMembrane, score
KOOEGFKL_01465 0.0 rgpF M Rhamnan synthesis protein F
KOOEGFKL_01466 4.8e-302 GT4 M transferase activity, transferring glycosyl groups
KOOEGFKL_01467 2.4e-228 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KOOEGFKL_01468 8e-143 rgpC GM Transport permease protein
KOOEGFKL_01469 2.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
KOOEGFKL_01470 1e-223 rgpA GT4 M Domain of unknown function (DUF1972)
KOOEGFKL_01471 1.3e-105 2.4.1.60 S Glycosyltransferase group 2 family protein
KOOEGFKL_01472 2.6e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
KOOEGFKL_01473 2.2e-125 ycbB S Glycosyl transferase family 2
KOOEGFKL_01474 4.6e-39 arnC M group 2 family protein
KOOEGFKL_01475 4.9e-142 M Glycosyltransferase group 2 family protein
KOOEGFKL_01476 2e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KOOEGFKL_01477 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOOEGFKL_01478 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KOOEGFKL_01479 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KOOEGFKL_01480 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOOEGFKL_01481 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOOEGFKL_01482 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KOOEGFKL_01483 1.2e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_01484 2.2e-199 arcT 2.6.1.1 E Aminotransferase
KOOEGFKL_01485 1.5e-136 ET ABC transporter
KOOEGFKL_01486 4.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
KOOEGFKL_01487 7.8e-79 mutT 3.6.1.55 F Nudix family
KOOEGFKL_01488 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOOEGFKL_01490 3.8e-77 S CAAX amino terminal protease family protein
KOOEGFKL_01491 2.4e-33 S CAAX amino terminal protease family protein
KOOEGFKL_01492 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KOOEGFKL_01493 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_01494 1.1e-16 XK27_00735
KOOEGFKL_01495 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOOEGFKL_01497 4.7e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOOEGFKL_01499 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KOOEGFKL_01500 3e-37 ycaO O OsmC-like protein
KOOEGFKL_01501 3.8e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KOOEGFKL_01503 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
KOOEGFKL_01504 2.3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KOOEGFKL_01505 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOOEGFKL_01506 2.6e-109 3.1.3.18 S IA, variant 1
KOOEGFKL_01507 2.2e-117 lrgB M effector of murein hydrolase
KOOEGFKL_01508 2.2e-55 lrgA S Effector of murein hydrolase LrgA
KOOEGFKL_01510 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KOOEGFKL_01511 5.3e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KOOEGFKL_01512 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOOEGFKL_01513 6.6e-104 wecD M Acetyltransferase (GNAT) domain
KOOEGFKL_01514 1.5e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOOEGFKL_01515 2.9e-117 GK ROK family
KOOEGFKL_01516 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KOOEGFKL_01517 2.1e-20 XK27_08050 O stress-induced mitochondrial fusion
KOOEGFKL_01518 6.8e-86 XK27_08050 O HflC and HflK could regulate a protease
KOOEGFKL_01520 5.2e-206 potD P spermidine putrescine ABC transporter
KOOEGFKL_01521 9.5e-133 potC P ABC-type spermidine putrescine transport system, permease component II
KOOEGFKL_01522 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KOOEGFKL_01523 3.6e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KOOEGFKL_01524 4.6e-171 murB 1.3.1.98 M cell wall formation
KOOEGFKL_01525 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KOOEGFKL_01526 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOOEGFKL_01527 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KOOEGFKL_01528 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KOOEGFKL_01529 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KOOEGFKL_01530 0.0 ydaO E amino acid
KOOEGFKL_01531 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOOEGFKL_01532 2e-36 ylqC L Belongs to the UPF0109 family
KOOEGFKL_01533 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KOOEGFKL_01534 6.9e-172 tehB 2.1.1.265 Q Methyltransferase
KOOEGFKL_01535 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
KOOEGFKL_01536 2.1e-74 S QueT transporter
KOOEGFKL_01537 1e-99 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KOOEGFKL_01538 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KOOEGFKL_01539 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOOEGFKL_01540 1.3e-85 ccl S cog cog4708
KOOEGFKL_01541 1.7e-160 rbn E Belongs to the UPF0761 family
KOOEGFKL_01542 6.1e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KOOEGFKL_01543 4.3e-231 ytoI K transcriptional regulator containing CBS domains
KOOEGFKL_01544 1e-96 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KOOEGFKL_01545 3.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOOEGFKL_01546 0.0 comEC S Competence protein ComEC
KOOEGFKL_01547 1.2e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KOOEGFKL_01548 2.9e-142 plsC 2.3.1.51 I Acyltransferase
KOOEGFKL_01549 4.7e-133 nodB3 G deacetylase
KOOEGFKL_01550 5.9e-180 L Transposase
KOOEGFKL_01551 1.2e-137 yabB 2.1.1.223 L Methyltransferase
KOOEGFKL_01552 1e-41 yazA L endonuclease containing a URI domain
KOOEGFKL_01553 1.2e-251 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KOOEGFKL_01554 2.3e-154 corA P CorA-like protein
KOOEGFKL_01555 2.5e-62 yjqA S Bacterial PH domain
KOOEGFKL_01556 8.7e-99 thiT S Thiamine transporter
KOOEGFKL_01557 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KOOEGFKL_01558 5.7e-198 yjbB G Permeases of the major facilitator superfamily
KOOEGFKL_01559 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KOOEGFKL_01560 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KOOEGFKL_01561 1.2e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOOEGFKL_01565 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KOOEGFKL_01566 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_01567 7.8e-107 P ABC transporter (Permease
KOOEGFKL_01568 1.7e-114 papP P ABC transporter (Permease
KOOEGFKL_01569 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOOEGFKL_01570 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KOOEGFKL_01571 0.0 copA 3.6.3.54 P P-type ATPase
KOOEGFKL_01572 1.6e-73 copY K Copper transport repressor, CopY TcrY family
KOOEGFKL_01573 6.6e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOOEGFKL_01574 2.5e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOOEGFKL_01575 1.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KOOEGFKL_01576 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KOOEGFKL_01577 6.6e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOOEGFKL_01578 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KOOEGFKL_01579 9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOOEGFKL_01580 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KOOEGFKL_01581 1.5e-56
KOOEGFKL_01582 0.0 ctpE P E1-E2 ATPase
KOOEGFKL_01583 6.1e-27
KOOEGFKL_01584 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KOOEGFKL_01585 6.6e-47 L transposase activity
KOOEGFKL_01586 4.1e-66 K transcriptional regulator, MerR family
KOOEGFKL_01587 8.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
KOOEGFKL_01588 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KOOEGFKL_01589 1.8e-62 XK27_02560 S cog cog2151
KOOEGFKL_01590 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOOEGFKL_01591 7.7e-227 ytfP S Flavoprotein
KOOEGFKL_01593 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOOEGFKL_01594 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KOOEGFKL_01595 3.5e-183 ecsB U ABC transporter
KOOEGFKL_01596 2.3e-133 ecsA V abc transporter atp-binding protein
KOOEGFKL_01597 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KOOEGFKL_01598 1.3e-11
KOOEGFKL_01599 5.1e-12 S CD20-like family
KOOEGFKL_01600 7.3e-107
KOOEGFKL_01601 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KOOEGFKL_01602 7.9e-202 ylbM S Belongs to the UPF0348 family
KOOEGFKL_01603 2e-140 yqeM Q Methyltransferase domain protein
KOOEGFKL_01604 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOOEGFKL_01605 8.9e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KOOEGFKL_01606 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOOEGFKL_01607 3.5e-49 yhbY J RNA-binding protein
KOOEGFKL_01608 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KOOEGFKL_01609 1.8e-98 yqeG S hydrolase of the HAD superfamily
KOOEGFKL_01610 8.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOOEGFKL_01611 1.4e-65
KOOEGFKL_01612 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOOEGFKL_01613 2.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOOEGFKL_01614 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOOEGFKL_01615 1.5e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
KOOEGFKL_01616 7.4e-32 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KOOEGFKL_01617 9.2e-253 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOOEGFKL_01618 3e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOOEGFKL_01619 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
KOOEGFKL_01620 3.4e-100 pncA Q isochorismatase
KOOEGFKL_01621 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KOOEGFKL_01622 1.8e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KOOEGFKL_01623 5.3e-75 XK27_03180 T universal stress protein
KOOEGFKL_01626 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOOEGFKL_01627 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KOOEGFKL_01628 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KOOEGFKL_01629 0.0 yjcE P NhaP-type Na H and K H antiporters
KOOEGFKL_01631 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KOOEGFKL_01632 1.3e-184 yhcC S radical SAM protein
KOOEGFKL_01633 8.4e-196 ylbL T Belongs to the peptidase S16 family
KOOEGFKL_01634 3.5e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOOEGFKL_01635 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KOOEGFKL_01636 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOOEGFKL_01637 1.9e-09 S Protein of unknown function (DUF4059)
KOOEGFKL_01638 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
KOOEGFKL_01639 1.1e-173 yxeN P ABC transporter (Permease
KOOEGFKL_01640 4.1e-150 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KOOEGFKL_01642 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOOEGFKL_01643 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KOOEGFKL_01644 1.1e-63 cah 4.2.1.1 P carbonic anhydrase
KOOEGFKL_01645 1.3e-38 cah 4.2.1.1 P carbonate dehydratase activity
KOOEGFKL_01646 1.3e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOOEGFKL_01647 8.4e-45 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KOOEGFKL_01648 6.3e-45 D nuclear chromosome segregation
KOOEGFKL_01649 6.5e-31 D nuclear chromosome segregation
KOOEGFKL_01650 5.4e-22 L Phage integrase family
KOOEGFKL_01651 7.1e-116 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
KOOEGFKL_01652 5.8e-127 ybbM S transport system, permease component
KOOEGFKL_01653 8e-117 ybbL S abc transporter atp-binding protein
KOOEGFKL_01654 2.2e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KOOEGFKL_01655 3.9e-139 cppA E CppA N-terminal
KOOEGFKL_01656 3.2e-34 V CAAX protease self-immunity
KOOEGFKL_01657 6.8e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KOOEGFKL_01658 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KOOEGFKL_01661 3e-47 spiA K sequence-specific DNA binding
KOOEGFKL_01662 2.9e-28 blpT
KOOEGFKL_01663 6.7e-98 blpT
KOOEGFKL_01664 3.9e-122 L Transposase
KOOEGFKL_01665 1.2e-165 L integrase core domain
KOOEGFKL_01670 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
KOOEGFKL_01671 2.6e-132 agrA KT phosphorelay signal transduction system
KOOEGFKL_01672 3.8e-238 blpH 2.7.13.3 T protein histidine kinase activity
KOOEGFKL_01674 4.7e-236 mesE M Transport protein ComB
KOOEGFKL_01675 3.7e-252 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOOEGFKL_01676 7.6e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOOEGFKL_01677 0.0 mdlB V abc transporter atp-binding protein
KOOEGFKL_01678 0.0 mdlA V abc transporter atp-binding protein
KOOEGFKL_01680 8.5e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KOOEGFKL_01681 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KOOEGFKL_01682 2.4e-66 yutD J protein conserved in bacteria
KOOEGFKL_01683 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KOOEGFKL_01685 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KOOEGFKL_01686 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOOEGFKL_01687 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KOOEGFKL_01688 8.1e-46 ftsL D cell division protein FtsL
KOOEGFKL_01689 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOOEGFKL_01690 5.8e-86
KOOEGFKL_01691 2.9e-57
KOOEGFKL_01692 7.7e-18 D nuclear chromosome segregation
KOOEGFKL_01693 1e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOOEGFKL_01694 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOOEGFKL_01695 3.5e-283 XK27_00765
KOOEGFKL_01696 1.8e-133 ecsA_2 V abc transporter atp-binding protein
KOOEGFKL_01697 6.4e-103 S Protein of unknown function (DUF554)
KOOEGFKL_01698 1.6e-11 S Protein of unknown function (DUF554)
KOOEGFKL_01699 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KOOEGFKL_01700 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KOOEGFKL_01701 1.9e-31 liaI S membrane
KOOEGFKL_01702 1.9e-64 liaI S membrane
KOOEGFKL_01703 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
KOOEGFKL_01704 6.2e-66 KT response to antibiotic
KOOEGFKL_01705 3.5e-17 KT response to antibiotic
KOOEGFKL_01706 5.6e-80 yebC M Membrane
KOOEGFKL_01707 4.8e-15 yebC M Membrane
KOOEGFKL_01708 2.8e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KOOEGFKL_01709 5.2e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KOOEGFKL_01710 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KOOEGFKL_01711 1.7e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOOEGFKL_01712 1.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOOEGFKL_01713 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOOEGFKL_01714 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOOEGFKL_01715 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOOEGFKL_01717 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOOEGFKL_01718 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KOOEGFKL_01719 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
KOOEGFKL_01720 4.1e-291 scrB 3.2.1.26 GH32 G invertase
KOOEGFKL_01721 4.9e-179 scrR K Transcriptional
KOOEGFKL_01722 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOOEGFKL_01723 7.5e-62 yqhY S protein conserved in bacteria
KOOEGFKL_01724 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOOEGFKL_01725 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KOOEGFKL_01726 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KOOEGFKL_01729 1.9e-44 V 'abc transporter, ATP-binding protein
KOOEGFKL_01730 4.1e-21 V 'abc transporter, ATP-binding protein
KOOEGFKL_01733 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KOOEGFKL_01734 2e-169 corA P COG0598 Mg2 and Co2 transporters
KOOEGFKL_01735 4.1e-124 XK27_01040 S Pfam PF06570
KOOEGFKL_01737 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOOEGFKL_01738 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOOEGFKL_01739 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KOOEGFKL_01740 1.2e-41 XK27_05745
KOOEGFKL_01741 4.2e-230 mutY L A G-specific adenine glycosylase
KOOEGFKL_01745 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOOEGFKL_01746 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KOOEGFKL_01747 1.1e-92 cvpA S toxin biosynthetic process
KOOEGFKL_01748 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KOOEGFKL_01749 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOOEGFKL_01750 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KOOEGFKL_01751 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KOOEGFKL_01752 8.8e-48 azlD E branched-chain amino acid
KOOEGFKL_01753 2.7e-115 azlC E AzlC protein
KOOEGFKL_01754 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOOEGFKL_01755 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KOOEGFKL_01756 1.6e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KOOEGFKL_01757 2.5e-33 ykzG S Belongs to the UPF0356 family
KOOEGFKL_01758 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOOEGFKL_01759 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KOOEGFKL_01760 8.5e-63 glnR K Transcriptional regulator
KOOEGFKL_01761 1.8e-87 S Fusaric acid resistance protein-like
KOOEGFKL_01762 3.3e-12
KOOEGFKL_01763 1.1e-30
KOOEGFKL_01764 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KOOEGFKL_01765 5.7e-43 L transposase activity
KOOEGFKL_01766 5.7e-23 L Transposase
KOOEGFKL_01767 7.7e-34 L transposition
KOOEGFKL_01768 2.9e-87 L Integrase core domain protein
KOOEGFKL_01769 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOOEGFKL_01770 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOOEGFKL_01771 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOOEGFKL_01772 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOOEGFKL_01773 7e-142 purR 2.4.2.7 F operon repressor
KOOEGFKL_01774 6.9e-178 cbf S 3'-5' exoribonuclease yhaM
KOOEGFKL_01775 1.5e-172 rmuC S RmuC domain protein
KOOEGFKL_01776 3.5e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
KOOEGFKL_01777 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KOOEGFKL_01778 3.8e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOOEGFKL_01780 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOOEGFKL_01781 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KOOEGFKL_01782 4.1e-144 tatD L Hydrolase, tatd
KOOEGFKL_01783 5.5e-74 yccU S CoA-binding protein
KOOEGFKL_01784 4.8e-51 trxA O Belongs to the thioredoxin family
KOOEGFKL_01785 6.6e-142 S Macro domain protein
KOOEGFKL_01786 1e-237 L Transposase
KOOEGFKL_01787 4.5e-09 L thioesterase
KOOEGFKL_01788 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KOOEGFKL_01792 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOOEGFKL_01793 2.2e-84 L Transposase
KOOEGFKL_01794 1e-13 rpmH J Ribosomal protein L34
KOOEGFKL_01795 3.2e-184 jag S RNA-binding protein
KOOEGFKL_01796 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOOEGFKL_01797 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOOEGFKL_01798 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KOOEGFKL_01799 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOOEGFKL_01800 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOOEGFKL_01801 3e-81 amiA E transmembrane transport
KOOEGFKL_01802 5e-69 amiA E transmembrane transport
KOOEGFKL_01803 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOOEGFKL_01804 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOOEGFKL_01805 9.2e-51 S Protein of unknown function (DUF3397)
KOOEGFKL_01806 4.6e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KOOEGFKL_01807 7.9e-35 WQ51_05710 S Mitochondrial biogenesis AIM24
KOOEGFKL_01808 2.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOOEGFKL_01809 2.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KOOEGFKL_01810 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
KOOEGFKL_01811 1.7e-75 XK27_09620 S reductase
KOOEGFKL_01812 1.1e-40 XK27_09615 C reductase
KOOEGFKL_01813 1.6e-138 XK27_09615 C reductase
KOOEGFKL_01814 1.1e-07 fnt P Formate nitrite transporter
KOOEGFKL_01815 2.9e-63 fnt P Formate nitrite transporter
KOOEGFKL_01816 1.2e-32 XK27_08585 S Psort location CytoplasmicMembrane, score
KOOEGFKL_01817 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KOOEGFKL_01818 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KOOEGFKL_01819 1.2e-165 L integrase core domain
KOOEGFKL_01820 3.9e-122 L Transposase
KOOEGFKL_01821 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KOOEGFKL_01822 5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KOOEGFKL_01823 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KOOEGFKL_01824 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KOOEGFKL_01825 2.3e-47 S glycolate biosynthetic process
KOOEGFKL_01826 4e-65 S phosphatase activity
KOOEGFKL_01827 2.2e-156 rrmA 2.1.1.187 Q methyltransferase
KOOEGFKL_01830 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOOEGFKL_01831 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOOEGFKL_01832 8.3e-37 yeeD O sulfur carrier activity
KOOEGFKL_01833 8.6e-190 yeeE S Sulphur transport
KOOEGFKL_01834 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOOEGFKL_01835 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KOOEGFKL_01836 1.2e-08 XK27_10305 S Domain of unknown function (DUF4651)
KOOEGFKL_01837 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KOOEGFKL_01838 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOOEGFKL_01839 4.3e-110 S CAAX amino terminal protease family protein
KOOEGFKL_01841 1.4e-66 V CAAX protease self-immunity
KOOEGFKL_01842 8.8e-27 lanR K sequence-specific DNA binding
KOOEGFKL_01843 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOOEGFKL_01844 5e-176 ytxK 2.1.1.72 L DNA methylase
KOOEGFKL_01845 6.8e-13 comGF U Putative Competence protein ComGF
KOOEGFKL_01846 1.3e-70 comGF U Competence protein ComGF
KOOEGFKL_01847 1.4e-15 NU Type II secretory pathway pseudopilin
KOOEGFKL_01848 3e-57 cglD NU Competence protein
KOOEGFKL_01849 8.5e-43 comGC U Required for transformation and DNA binding
KOOEGFKL_01850 1.1e-156 cglB U protein transport across the cell outer membrane
KOOEGFKL_01851 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KOOEGFKL_01852 2.9e-68 S cog cog4699
KOOEGFKL_01853 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOEGFKL_01854 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOEGFKL_01855 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOOEGFKL_01856 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOOEGFKL_01857 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOOEGFKL_01858 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KOOEGFKL_01859 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KOOEGFKL_01860 5.2e-84 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOOEGFKL_01861 3e-60 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOOEGFKL_01862 2.8e-165 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOOEGFKL_01863 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
KOOEGFKL_01864 1.8e-57 asp S cog cog1302
KOOEGFKL_01865 9.3e-226 norN V Mate efflux family protein
KOOEGFKL_01866 9.2e-278 thrC 4.2.3.1 E Threonine synthase
KOOEGFKL_01867 1.6e-73 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOOEGFKL_01868 1e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOOEGFKL_01869 2.3e-137 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KOOEGFKL_01870 5.1e-66 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KOOEGFKL_01871 0.0 pepO 3.4.24.71 O Peptidase family M13
KOOEGFKL_01872 3.3e-39 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOOEGFKL_01873 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOOEGFKL_01874 1.7e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOOEGFKL_01875 4.2e-11 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOOEGFKL_01876 8.3e-55 treB 2.7.1.201 G PTS System
KOOEGFKL_01877 5.8e-21 treR K DNA-binding transcription factor activity
KOOEGFKL_01878 6.6e-87 treR K trehalose operon
KOOEGFKL_01879 3.3e-95 ywlG S Belongs to the UPF0340 family
KOOEGFKL_01882 4.1e-33 L PFAM Integrase, catalytic core
KOOEGFKL_01883 2e-94 L PFAM Integrase, catalytic core
KOOEGFKL_01884 1.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
KOOEGFKL_01886 3e-110 6.3.2.2 H ergothioneine biosynthetic process
KOOEGFKL_01887 2.7e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
KOOEGFKL_01888 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KOOEGFKL_01889 4.1e-33 L PFAM Integrase, catalytic core
KOOEGFKL_01890 5.9e-49 L PFAM Integrase, catalytic core
KOOEGFKL_01891 5.3e-50 L PFAM Integrase, catalytic core
KOOEGFKL_01892 3.3e-62 rplQ J ribosomal protein l17
KOOEGFKL_01893 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOEGFKL_01894 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOOEGFKL_01895 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOOEGFKL_01896 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KOOEGFKL_01897 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOOEGFKL_01898 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOOEGFKL_01899 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOOEGFKL_01900 4.4e-58 rplO J binds to the 23S rRNA
KOOEGFKL_01901 2.5e-23 rpmD J ribosomal protein l30
KOOEGFKL_01902 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOOEGFKL_01903 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOOEGFKL_01904 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOOEGFKL_01905 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOOEGFKL_01906 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOOEGFKL_01907 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOOEGFKL_01908 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOOEGFKL_01909 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOOEGFKL_01910 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOOEGFKL_01911 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KOOEGFKL_01912 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOOEGFKL_01913 1e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOOEGFKL_01914 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOOEGFKL_01915 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOOEGFKL_01916 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOOEGFKL_01917 4.1e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOOEGFKL_01918 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KOOEGFKL_01919 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOOEGFKL_01920 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KOOEGFKL_01921 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOOEGFKL_01922 0.0 XK27_09800 I Acyltransferase
KOOEGFKL_01923 1.7e-35 XK27_09805 S MORN repeat protein
KOOEGFKL_01924 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOOEGFKL_01925 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOOEGFKL_01926 4.1e-84 adk 2.7.4.3 F topology modulation protein
KOOEGFKL_01927 3.1e-172 yxaM EGP Major facilitator Superfamily
KOOEGFKL_01928 1.3e-196 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
KOOEGFKL_01929 1.4e-53 L Transposase
KOOEGFKL_01930 4.1e-147 L Transposase
KOOEGFKL_01932 3.4e-155 Z012_04635 K sequence-specific DNA binding
KOOEGFKL_01933 0.0 KLT serine threonine protein kinase
KOOEGFKL_01934 2.1e-280 V ABC transporter
KOOEGFKL_01935 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KOOEGFKL_01936 1.3e-128 Z012_04635 K sequence-specific DNA binding
KOOEGFKL_01938 3.6e-232 C Radical SAM
KOOEGFKL_01939 5.1e-287 V ABC transporter transmembrane region
KOOEGFKL_01940 2.5e-89 K sequence-specific DNA binding
KOOEGFKL_01941 6.7e-98 int L Belongs to the 'phage' integrase family
KOOEGFKL_01943 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KOOEGFKL_01944 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KOOEGFKL_01945 2.2e-44 yrzL S Belongs to the UPF0297 family
KOOEGFKL_01946 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOOEGFKL_01947 1.3e-45 yrzB S Belongs to the UPF0473 family
KOOEGFKL_01948 1.7e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
KOOEGFKL_01949 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KOOEGFKL_01950 7.5e-14
KOOEGFKL_01951 1.7e-90 XK27_10930 K acetyltransferase
KOOEGFKL_01952 4.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOOEGFKL_01953 1.5e-144 yaaA S Belongs to the UPF0246 family
KOOEGFKL_01954 1.3e-163 XK27_01785 S cog cog1284
KOOEGFKL_01955 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KOOEGFKL_01957 2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KOOEGFKL_01958 1.2e-52 metE 2.1.1.14 E Methionine synthase
KOOEGFKL_01959 5.2e-55 metE 2.1.1.14 E Methionine synthase
KOOEGFKL_01960 1.4e-36 metE 2.1.1.14 E Methionine synthase
KOOEGFKL_01961 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KOOEGFKL_01962 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOOEGFKL_01964 2.6e-49 yegS 2.7.1.107 I lipid kinase activity
KOOEGFKL_01965 4.2e-96 S Hydrophobic domain protein
KOOEGFKL_01967 3.7e-27 S Membrane
KOOEGFKL_01968 1.6e-100
KOOEGFKL_01969 1.8e-23 S Small integral membrane protein
KOOEGFKL_01970 3.1e-85 M Protein conserved in bacteria
KOOEGFKL_01971 1.1e-11 K CsbD-like
KOOEGFKL_01972 1.4e-98 nudL L hydrolase
KOOEGFKL_01973 3.4e-13 nudL L hydrolase
KOOEGFKL_01974 8.8e-48 K transcriptional regulator, PadR family
KOOEGFKL_01976 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
KOOEGFKL_01977 1.6e-112 S Putative adhesin
KOOEGFKL_01978 9.9e-157 XK27_06930 V domain protein
KOOEGFKL_01979 6.4e-96 XK27_06935 K transcriptional regulator
KOOEGFKL_01980 3.1e-54 ypaA S membrane
KOOEGFKL_01981 1.4e-08
KOOEGFKL_01982 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOOEGFKL_01983 8.2e-48 veg S Biofilm formation stimulator VEG
KOOEGFKL_01984 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KOOEGFKL_01985 2.2e-68 rplI J binds to the 23S rRNA
KOOEGFKL_01986 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KOOEGFKL_01987 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KOOEGFKL_01988 1.5e-77 F NUDIX domain
KOOEGFKL_01989 1.1e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KOOEGFKL_01990 0.0 S Bacterial membrane protein, YfhO
KOOEGFKL_01991 9.6e-67 isaA GH23 M Immunodominant staphylococcal antigen A
KOOEGFKL_01992 3.1e-93 lytE M LysM domain protein
KOOEGFKL_01993 1e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOOEGFKL_01994 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOOEGFKL_01995 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOOEGFKL_01996 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOOEGFKL_01997 1.2e-136 ymfM S sequence-specific DNA binding
KOOEGFKL_01998 9.2e-242 ymfH S Peptidase M16
KOOEGFKL_01999 8.1e-235 ymfF S Peptidase M16
KOOEGFKL_02000 1.6e-45 yaaA S S4 domain protein YaaA
KOOEGFKL_02001 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOOEGFKL_02002 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KOOEGFKL_02003 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KOOEGFKL_02004 1.6e-152 yvjA S membrane
KOOEGFKL_02005 1.9e-305 ybiT S abc transporter atp-binding protein
KOOEGFKL_02006 0.0 XK27_10405 S Bacterial membrane protein YfhO
KOOEGFKL_02010 1.1e-119 yoaK S Psort location CytoplasmicMembrane, score
KOOEGFKL_02011 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOOEGFKL_02012 4.3e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KOOEGFKL_02013 4.2e-133 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)