ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPCKIGJE_00001 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPCKIGJE_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPCKIGJE_00003 1.1e-29 yyzM S Protein conserved in bacteria
HPCKIGJE_00004 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPCKIGJE_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPCKIGJE_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPCKIGJE_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HPCKIGJE_00008 2.7e-61 divIC D Septum formation initiator
HPCKIGJE_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HPCKIGJE_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPCKIGJE_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPCKIGJE_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPCKIGJE_00014 3.8e-103 L Transposase
HPCKIGJE_00015 4e-50 L Transposase
HPCKIGJE_00016 6.9e-52 L transposase activity
HPCKIGJE_00017 2.5e-23 L Transposase
HPCKIGJE_00018 4.2e-29 L transposition
HPCKIGJE_00031 5.3e-11
HPCKIGJE_00037 5.5e-139 mreC M Involved in formation and maintenance of cell shape
HPCKIGJE_00038 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HPCKIGJE_00039 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
HPCKIGJE_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPCKIGJE_00041 2.9e-218 araT 2.6.1.1 E Aminotransferase
HPCKIGJE_00042 7e-144 recO L Involved in DNA repair and RecF pathway recombination
HPCKIGJE_00043 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPCKIGJE_00044 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPCKIGJE_00045 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HPCKIGJE_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPCKIGJE_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPCKIGJE_00048 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HPCKIGJE_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPCKIGJE_00050 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HPCKIGJE_00051 6.1e-79 L transposase activity
HPCKIGJE_00052 1e-51 L transposition
HPCKIGJE_00053 3.8e-31 L Integrase core domain protein
HPCKIGJE_00054 3.7e-159 S CHAP domain
HPCKIGJE_00055 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
HPCKIGJE_00056 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPCKIGJE_00057 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPCKIGJE_00058 9.2e-141 1.1.1.169 H Ketopantoate reductase
HPCKIGJE_00059 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPCKIGJE_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HPCKIGJE_00061 8.2e-70 argR K Regulates arginine biosynthesis genes
HPCKIGJE_00062 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HPCKIGJE_00063 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPCKIGJE_00064 7e-34 S Protein of unknown function (DUF3021)
HPCKIGJE_00065 1.2e-61 KT phosphorelay signal transduction system
HPCKIGJE_00067 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPCKIGJE_00069 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPCKIGJE_00070 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HPCKIGJE_00071 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
HPCKIGJE_00072 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPCKIGJE_00073 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HPCKIGJE_00079 2.6e-10
HPCKIGJE_00082 1.9e-07
HPCKIGJE_00087 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPCKIGJE_00088 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HPCKIGJE_00089 1.6e-35 XK27_02060 S Transglycosylase associated protein
HPCKIGJE_00090 2.6e-55 badR K DNA-binding transcription factor activity
HPCKIGJE_00091 3.5e-97 S reductase
HPCKIGJE_00092 1.5e-30 L Integrase core domain protein
HPCKIGJE_00093 6.4e-41 L transposition
HPCKIGJE_00094 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
HPCKIGJE_00095 4.9e-99 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HPCKIGJE_00097 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HPCKIGJE_00098 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPCKIGJE_00099 1.1e-83 S Putative small multi-drug export protein
HPCKIGJE_00100 6.2e-76 ctsR K Belongs to the CtsR family
HPCKIGJE_00101 0.0 clpC O Belongs to the ClpA ClpB family
HPCKIGJE_00102 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPCKIGJE_00103 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPCKIGJE_00104 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPCKIGJE_00105 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPCKIGJE_00106 6.9e-144 S SseB protein N-terminal domain
HPCKIGJE_00107 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HPCKIGJE_00108 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPCKIGJE_00109 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPCKIGJE_00112 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPCKIGJE_00113 1e-84 yacP S RNA-binding protein containing a PIN domain
HPCKIGJE_00114 3.4e-155 degV S DegV family
HPCKIGJE_00115 1.8e-31 K helix-turn-helix
HPCKIGJE_00116 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPCKIGJE_00117 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPCKIGJE_00118 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HPCKIGJE_00119 1.6e-249 L Transposase
HPCKIGJE_00120 1.5e-35 K sequence-specific DNA binding
HPCKIGJE_00122 0.0 S Lantibiotic dehydratase, C terminus
HPCKIGJE_00123 2.4e-231 spaC2 V Lanthionine synthetase C family protein
HPCKIGJE_00124 4.3e-183 EGP Major facilitator Superfamily
HPCKIGJE_00125 5.9e-24 3.6.4.12
HPCKIGJE_00126 5.9e-91 3.6.4.12 K Divergent AAA domain protein
HPCKIGJE_00127 7.4e-225 int L Belongs to the 'phage' integrase family
HPCKIGJE_00128 1.8e-38 S Helix-turn-helix domain
HPCKIGJE_00129 2.2e-173
HPCKIGJE_00131 3.4e-75 isp2 S pathogenesis
HPCKIGJE_00132 5.7e-91 tnp L Transposase
HPCKIGJE_00133 3.3e-225 capA M Bacterial capsule synthesis protein
HPCKIGJE_00134 3.6e-39 gcvR T UPF0237 protein
HPCKIGJE_00135 1.9e-242 XK27_08635 S UPF0210 protein
HPCKIGJE_00136 2.2e-38 ais G alpha-ribazole phosphatase activity
HPCKIGJE_00137 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HPCKIGJE_00138 1.3e-102 acmA 3.2.1.17 NU amidase activity
HPCKIGJE_00139 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPCKIGJE_00140 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPCKIGJE_00141 9.8e-298 dnaK O Heat shock 70 kDa protein
HPCKIGJE_00142 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPCKIGJE_00143 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPCKIGJE_00144 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HPCKIGJE_00145 1.7e-60 hmpT S membrane
HPCKIGJE_00158 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HPCKIGJE_00159 2.5e-169 L Transposase
HPCKIGJE_00160 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HPCKIGJE_00161 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPCKIGJE_00162 1e-84
HPCKIGJE_00163 1.6e-77 sigH K DNA-templated transcription, initiation
HPCKIGJE_00164 9.3e-150 ykuT M mechanosensitive ion channel
HPCKIGJE_00165 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPCKIGJE_00166 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPCKIGJE_00167 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPCKIGJE_00168 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
HPCKIGJE_00169 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HPCKIGJE_00170 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
HPCKIGJE_00171 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPCKIGJE_00172 1.4e-42 F nucleotide catabolic process
HPCKIGJE_00173 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPCKIGJE_00174 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPCKIGJE_00175 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPCKIGJE_00176 1.8e-83 nrdI F Belongs to the NrdI family
HPCKIGJE_00177 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPCKIGJE_00178 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPCKIGJE_00179 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HPCKIGJE_00180 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HPCKIGJE_00181 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HPCKIGJE_00182 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HPCKIGJE_00183 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HPCKIGJE_00184 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPCKIGJE_00185 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPCKIGJE_00186 6.5e-202 yhjX P Major Facilitator
HPCKIGJE_00187 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPCKIGJE_00188 5e-94 V VanZ like family
HPCKIGJE_00189 1e-123 glnQ E abc transporter atp-binding protein
HPCKIGJE_00190 2e-275 glnP P ABC transporter
HPCKIGJE_00191 5.9e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPCKIGJE_00192 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPCKIGJE_00193 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
HPCKIGJE_00194 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HPCKIGJE_00195 6.3e-235 sufD O assembly protein SufD
HPCKIGJE_00196 5e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPCKIGJE_00197 9.5e-74 nifU C SUF system FeS assembly protein, NifU family
HPCKIGJE_00198 2.2e-273 sufB O assembly protein SufB
HPCKIGJE_00199 7e-10 oppA E ABC transporter substrate-binding protein
HPCKIGJE_00200 2e-138 oppA E ABC transporter substrate-binding protein
HPCKIGJE_00201 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPCKIGJE_00202 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPCKIGJE_00203 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPCKIGJE_00204 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPCKIGJE_00205 3e-27 oppD P Belongs to the ABC transporter superfamily
HPCKIGJE_00206 2.5e-32 oppD P Belongs to the ABC transporter superfamily
HPCKIGJE_00207 1.2e-62 oppD P Belongs to the ABC transporter superfamily
HPCKIGJE_00208 3.1e-43 oppD P Belongs to the ABC transporter superfamily
HPCKIGJE_00209 2.8e-61 oppF P Belongs to the ABC transporter superfamily
HPCKIGJE_00210 3.4e-62 oppF P Belongs to the ABC transporter superfamily
HPCKIGJE_00211 8.3e-23
HPCKIGJE_00212 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPCKIGJE_00213 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPCKIGJE_00214 1.9e-223 EGP Major facilitator Superfamily
HPCKIGJE_00215 9.1e-72 adcR K transcriptional
HPCKIGJE_00216 1.1e-135 adcC P ABC transporter, ATP-binding protein
HPCKIGJE_00217 7.9e-130 adcB P ABC transporter (Permease
HPCKIGJE_00218 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HPCKIGJE_00219 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HPCKIGJE_00220 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
HPCKIGJE_00221 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPCKIGJE_00222 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HPCKIGJE_00223 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
HPCKIGJE_00224 1.9e-127 yeeN K transcriptional regulatory protein
HPCKIGJE_00225 9.8e-50 yajC U protein transport
HPCKIGJE_00226 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPCKIGJE_00227 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HPCKIGJE_00228 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPCKIGJE_00229 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPCKIGJE_00230 0.0 WQ51_06230 S ABC transporter substrate binding protein
HPCKIGJE_00231 5.2e-142 cmpC S abc transporter atp-binding protein
HPCKIGJE_00232 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPCKIGJE_00233 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPCKIGJE_00234 4.4e-37 L Transposase
HPCKIGJE_00235 6.4e-18 L transposase activity
HPCKIGJE_00236 1.5e-30 L transposition
HPCKIGJE_00237 8.1e-45 L Transposase
HPCKIGJE_00238 4.1e-158 L COG2801 Transposase and inactivated derivatives
HPCKIGJE_00241 4.7e-43
HPCKIGJE_00242 6.8e-56 S TM2 domain
HPCKIGJE_00243 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPCKIGJE_00244 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPCKIGJE_00245 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
HPCKIGJE_00246 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HPCKIGJE_00247 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HPCKIGJE_00248 6e-55 cof Q phosphatase activity
HPCKIGJE_00249 6.2e-35 cof Q phosphatase activity
HPCKIGJE_00250 1.6e-137 glcR K transcriptional regulator (DeoR family)
HPCKIGJE_00251 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPCKIGJE_00253 3.8e-40 K transcriptional
HPCKIGJE_00254 7.4e-89 S thiolester hydrolase activity
HPCKIGJE_00255 5.6e-138 S COG1073 Hydrolases of the alpha beta superfamily
HPCKIGJE_00256 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPCKIGJE_00257 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPCKIGJE_00258 3.2e-77 yhaI L Membrane
HPCKIGJE_00259 5.1e-259 pepC 3.4.22.40 E aminopeptidase
HPCKIGJE_00260 1.6e-249 L Transposase
HPCKIGJE_00261 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPCKIGJE_00262 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPCKIGJE_00263 3.1e-95 ypsA S Belongs to the UPF0398 family
HPCKIGJE_00264 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPCKIGJE_00265 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPCKIGJE_00266 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HPCKIGJE_00267 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HPCKIGJE_00268 2.5e-23
HPCKIGJE_00269 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPCKIGJE_00270 7.3e-80 XK27_09675 K -acetyltransferase
HPCKIGJE_00271 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPCKIGJE_00272 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPCKIGJE_00273 5.2e-59 L Integrase core domain protein
HPCKIGJE_00274 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPCKIGJE_00275 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPCKIGJE_00276 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPCKIGJE_00277 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HPCKIGJE_00278 8.8e-98 ybhL S Belongs to the BI1 family
HPCKIGJE_00281 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPCKIGJE_00282 3.7e-91 K transcriptional regulator
HPCKIGJE_00283 7.6e-36 yneF S UPF0154 protein
HPCKIGJE_00284 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPCKIGJE_00285 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPCKIGJE_00286 3.5e-99 XK27_09740 S Phosphoesterase
HPCKIGJE_00287 7.8e-85 ykuL S CBS domain
HPCKIGJE_00288 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HPCKIGJE_00289 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPCKIGJE_00290 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPCKIGJE_00291 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPCKIGJE_00292 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPCKIGJE_00293 1.2e-258 trkH P Cation transport protein
HPCKIGJE_00294 1.5e-247 trkA P Potassium transporter peripheral membrane component
HPCKIGJE_00295 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPCKIGJE_00296 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPCKIGJE_00297 1.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HPCKIGJE_00298 5.6e-161 K sequence-specific DNA binding
HPCKIGJE_00299 1.2e-32 V protein secretion by the type I secretion system
HPCKIGJE_00300 1.1e-34 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPCKIGJE_00301 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPCKIGJE_00302 1.6e-25 V protein secretion by the type I secretion system
HPCKIGJE_00303 1.8e-27 comA V protein secretion by the type I secretion system
HPCKIGJE_00304 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPCKIGJE_00305 3.7e-51 yhaI L Membrane
HPCKIGJE_00306 6.7e-36 S Domain of unknown function (DUF4173)
HPCKIGJE_00307 9.2e-132 S Domain of unknown function (DUF4173)
HPCKIGJE_00308 6.8e-95 ureI S AmiS/UreI family transporter
HPCKIGJE_00309 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HPCKIGJE_00310 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HPCKIGJE_00311 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HPCKIGJE_00312 6.6e-78 ureE O enzyme active site formation
HPCKIGJE_00313 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HPCKIGJE_00314 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPCKIGJE_00315 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HPCKIGJE_00316 8.2e-16 cbiM P PDGLE domain
HPCKIGJE_00317 1.4e-150 cbiM P PDGLE domain
HPCKIGJE_00318 1.1e-136 P cobalt transport protein
HPCKIGJE_00319 1.6e-131 cbiO P ABC transporter
HPCKIGJE_00320 5.3e-153 ET amino acid transport
HPCKIGJE_00321 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPCKIGJE_00322 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HPCKIGJE_00323 3.8e-205 EGP Transmembrane secretion effector
HPCKIGJE_00324 4e-153 ET amino acid transport
HPCKIGJE_00325 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
HPCKIGJE_00326 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HPCKIGJE_00327 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HPCKIGJE_00328 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HPCKIGJE_00329 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPCKIGJE_00330 3e-98 metI P ABC transporter (Permease
HPCKIGJE_00331 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HPCKIGJE_00332 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HPCKIGJE_00333 8e-94 S UPF0397 protein
HPCKIGJE_00334 0.0 ykoD P abc transporter atp-binding protein
HPCKIGJE_00335 1.2e-146 cbiQ P cobalt transport
HPCKIGJE_00336 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPCKIGJE_00337 6.9e-11 ulaG S L-ascorbate 6-phosphate lactonase
HPCKIGJE_00338 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HPCKIGJE_00339 2.1e-244 P COG0168 Trk-type K transport systems, membrane components
HPCKIGJE_00340 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HPCKIGJE_00341 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
HPCKIGJE_00342 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPCKIGJE_00343 2.8e-282 T PhoQ Sensor
HPCKIGJE_00344 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPCKIGJE_00345 6.5e-218 dnaB L Replication initiation and membrane attachment
HPCKIGJE_00346 4.4e-166 dnaI L Primosomal protein DnaI
HPCKIGJE_00347 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPCKIGJE_00349 1.2e-34
HPCKIGJE_00350 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
HPCKIGJE_00351 3e-27 L Integrase core domain protein
HPCKIGJE_00352 5.7e-23 L Transposase
HPCKIGJE_00353 7.8e-28 L transposase activity
HPCKIGJE_00354 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPCKIGJE_00355 4.2e-62 manO S protein conserved in bacteria
HPCKIGJE_00356 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
HPCKIGJE_00357 2.3e-116 manM G pts system
HPCKIGJE_00358 1.1e-181 manL 2.7.1.191 G pts system
HPCKIGJE_00359 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HPCKIGJE_00360 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HPCKIGJE_00361 1.9e-248 pbuO S permease
HPCKIGJE_00362 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HPCKIGJE_00363 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HPCKIGJE_00364 2.5e-220 brpA K Transcriptional
HPCKIGJE_00365 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HPCKIGJE_00366 3.1e-212 nusA K Participates in both transcription termination and antitermination
HPCKIGJE_00367 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HPCKIGJE_00368 2e-46 ylxQ J ribosomal protein
HPCKIGJE_00369 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPCKIGJE_00370 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPCKIGJE_00371 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HPCKIGJE_00372 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
HPCKIGJE_00373 2.1e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HPCKIGJE_00374 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPCKIGJE_00375 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HPCKIGJE_00376 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HPCKIGJE_00377 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HPCKIGJE_00378 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HPCKIGJE_00380 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPCKIGJE_00381 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPCKIGJE_00382 1.2e-74 ylbF S Belongs to the UPF0342 family
HPCKIGJE_00383 7.1e-46 ylbG S UPF0298 protein
HPCKIGJE_00384 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HPCKIGJE_00385 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HPCKIGJE_00386 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HPCKIGJE_00387 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HPCKIGJE_00388 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HPCKIGJE_00389 6.8e-69 acuB S IMP dehydrogenase activity
HPCKIGJE_00390 8.9e-41 acuB S IMP dehydrogenase activity
HPCKIGJE_00391 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HPCKIGJE_00392 1.1e-110 yvyE 3.4.13.9 S YigZ family
HPCKIGJE_00393 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HPCKIGJE_00394 1.7e-122 comFC S Competence protein
HPCKIGJE_00395 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPCKIGJE_00403 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPCKIGJE_00404 6.4e-108 S Domain of unknown function (DUF1803)
HPCKIGJE_00405 7.8e-102 ygaC J Belongs to the UPF0374 family
HPCKIGJE_00406 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPCKIGJE_00407 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPCKIGJE_00408 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
HPCKIGJE_00409 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPCKIGJE_00410 2.1e-114 S Haloacid dehalogenase-like hydrolase
HPCKIGJE_00411 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HPCKIGJE_00412 5.8e-71 marR K Transcriptional regulator, MarR family
HPCKIGJE_00413 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPCKIGJE_00414 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPCKIGJE_00415 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HPCKIGJE_00416 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HPCKIGJE_00417 1.3e-126 IQ reductase
HPCKIGJE_00418 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPCKIGJE_00419 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPCKIGJE_00420 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPCKIGJE_00421 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HPCKIGJE_00422 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPCKIGJE_00423 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HPCKIGJE_00424 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPCKIGJE_00425 4.4e-126 tnp L Transposase
HPCKIGJE_00427 8e-277 S Protein of unknown function (DUF3114)
HPCKIGJE_00428 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
HPCKIGJE_00429 7.7e-198 V (ABC) transporter
HPCKIGJE_00430 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
HPCKIGJE_00431 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
HPCKIGJE_00432 1.1e-113 K sequence-specific DNA binding
HPCKIGJE_00433 8.4e-155 L COG2801 Transposase and inactivated derivatives
HPCKIGJE_00434 6.6e-38 L transposase activity
HPCKIGJE_00435 3.5e-206 rny D Endoribonuclease that initiates mRNA decay
HPCKIGJE_00436 1.8e-84 L Transposase
HPCKIGJE_00437 2.1e-113 fruR K transcriptional
HPCKIGJE_00438 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPCKIGJE_00439 2.1e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
HPCKIGJE_00440 4e-238 fruA 2.7.1.202 G phosphotransferase system
HPCKIGJE_00441 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPCKIGJE_00442 2.8e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPCKIGJE_00444 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HPCKIGJE_00445 1.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPCKIGJE_00446 8.4e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HPCKIGJE_00447 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HPCKIGJE_00448 6.4e-29 2.3.1.128 K acetyltransferase
HPCKIGJE_00449 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPCKIGJE_00450 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPCKIGJE_00451 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPCKIGJE_00452 2.6e-64 WQ51_03320 S cog cog4835
HPCKIGJE_00453 6.4e-61 XK27_08360 S EDD domain protein, DegV family
HPCKIGJE_00454 5.5e-75 XK27_08360 S EDD domain protein, DegV family
HPCKIGJE_00455 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPCKIGJE_00456 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPCKIGJE_00457 0.0 yfmR S abc transporter atp-binding protein
HPCKIGJE_00458 1.2e-24 U response to pH
HPCKIGJE_00459 2.1e-137 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HPCKIGJE_00460 1.6e-137 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HPCKIGJE_00461 1.3e-58 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HPCKIGJE_00462 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HPCKIGJE_00463 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPCKIGJE_00464 1.9e-77 K DNA-binding transcription factor activity
HPCKIGJE_00465 2.5e-311 lmrA1 V abc transporter atp-binding protein
HPCKIGJE_00466 0.0 lmrA2 V abc transporter atp-binding protein
HPCKIGJE_00467 1.4e-45 K Acetyltransferase (GNAT) family
HPCKIGJE_00468 3.2e-78 sptS 2.7.13.3 T Histidine kinase
HPCKIGJE_00469 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPCKIGJE_00470 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPCKIGJE_00471 5.3e-161 cvfB S Protein conserved in bacteria
HPCKIGJE_00472 7.4e-35 yozE S Belongs to the UPF0346 family
HPCKIGJE_00473 6.7e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
HPCKIGJE_00474 2.3e-61 rlpA M LysM domain protein
HPCKIGJE_00475 1e-190 phoH T phosphate starvation-inducible protein PhoH
HPCKIGJE_00479 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPCKIGJE_00480 1.8e-164 K transcriptional regulator (lysR family)
HPCKIGJE_00481 1.4e-186 coiA 3.6.4.12 S Competence protein
HPCKIGJE_00482 0.0 pepF E oligoendopeptidase F
HPCKIGJE_00483 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HPCKIGJE_00484 2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HPCKIGJE_00485 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPCKIGJE_00486 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HPCKIGJE_00487 1.3e-147 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HPCKIGJE_00488 2.3e-103 3.4.17.14, 3.5.1.28 NU amidase activity
HPCKIGJE_00489 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HPCKIGJE_00490 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HPCKIGJE_00491 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPCKIGJE_00492 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPCKIGJE_00493 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HPCKIGJE_00494 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HPCKIGJE_00495 2.2e-130 yxkH G deacetylase
HPCKIGJE_00496 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HPCKIGJE_00497 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPCKIGJE_00498 5.5e-153 rarD S Transporter
HPCKIGJE_00499 2.2e-15 T peptidase
HPCKIGJE_00500 8.9e-14 coiA 3.6.4.12 S Competence protein
HPCKIGJE_00501 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPCKIGJE_00502 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPCKIGJE_00503 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPCKIGJE_00504 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPCKIGJE_00505 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HPCKIGJE_00506 3.3e-78 atpF C ATP synthase F(0) sector subunit b
HPCKIGJE_00507 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPCKIGJE_00508 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPCKIGJE_00509 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPCKIGJE_00510 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPCKIGJE_00511 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPCKIGJE_00512 2.8e-230 ftsW D Belongs to the SEDS family
HPCKIGJE_00513 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPCKIGJE_00514 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPCKIGJE_00515 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPCKIGJE_00516 5.4e-161 holB 2.7.7.7 L dna polymerase iii
HPCKIGJE_00517 5.8e-133 yaaT S stage 0 sporulation protein
HPCKIGJE_00518 9.5e-55 yabA L Involved in initiation control of chromosome replication
HPCKIGJE_00519 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPCKIGJE_00520 7.5e-233 amt P Ammonium Transporter
HPCKIGJE_00521 1.1e-53 glnB K Belongs to the P(II) protein family
HPCKIGJE_00522 4.9e-106 mur1 NU mannosyl-glycoprotein
HPCKIGJE_00523 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HPCKIGJE_00524 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
HPCKIGJE_00525 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPCKIGJE_00526 1.8e-53
HPCKIGJE_00527 7.5e-26
HPCKIGJE_00528 1.5e-59
HPCKIGJE_00529 6.1e-63 S membrane
HPCKIGJE_00530 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPCKIGJE_00531 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPCKIGJE_00532 4.5e-39 ynzC S UPF0291 protein
HPCKIGJE_00533 1.8e-254 cycA E permease
HPCKIGJE_00534 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
HPCKIGJE_00535 1.7e-70 pts33BCA G pts system
HPCKIGJE_00536 1.1e-76 pts33BCA G pts system
HPCKIGJE_00537 5.5e-84 pts33BCA G pts system
HPCKIGJE_00538 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPCKIGJE_00539 1.2e-165 L integrase core domain
HPCKIGJE_00540 3.9e-122 L Transposase
HPCKIGJE_00545 1.4e-167 fhuR K transcriptional regulator (lysR family)
HPCKIGJE_00546 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPCKIGJE_00547 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPCKIGJE_00548 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPCKIGJE_00549 4.9e-227 pyrP F uracil Permease
HPCKIGJE_00550 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPCKIGJE_00551 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HPCKIGJE_00552 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HPCKIGJE_00553 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
HPCKIGJE_00554 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPCKIGJE_00555 3.6e-35 V efflux transmembrane transporter activity
HPCKIGJE_00556 1.2e-35 V efflux transmembrane transporter activity
HPCKIGJE_00557 1.1e-24 ytrF V efflux transmembrane transporter activity
HPCKIGJE_00558 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPCKIGJE_00559 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPCKIGJE_00560 8.8e-223 L Transposase
HPCKIGJE_00562 0.0 mdlB V abc transporter atp-binding protein
HPCKIGJE_00563 0.0 lmrA V abc transporter atp-binding protein
HPCKIGJE_00564 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPCKIGJE_00565 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPCKIGJE_00566 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HPCKIGJE_00567 2.5e-132 rr02 KT response regulator
HPCKIGJE_00568 1.6e-218 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HPCKIGJE_00569 2.8e-168 V ABC transporter
HPCKIGJE_00570 5.4e-122 sagI S ABC-2 type transporter
HPCKIGJE_00571 1e-195 yceA S Belongs to the UPF0176 family
HPCKIGJE_00572 8e-28 XK27_00085 K Transcriptional
HPCKIGJE_00573 2.7e-24
HPCKIGJE_00574 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
HPCKIGJE_00575 3.4e-56 S VIT family
HPCKIGJE_00576 3.4e-43 S VIT family
HPCKIGJE_00577 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPCKIGJE_00578 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HPCKIGJE_00579 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HPCKIGJE_00580 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HPCKIGJE_00581 3e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPCKIGJE_00582 4.6e-105 GBS0088 J protein conserved in bacteria
HPCKIGJE_00583 5.3e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HPCKIGJE_00584 1.3e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPCKIGJE_00585 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HPCKIGJE_00586 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPCKIGJE_00587 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPCKIGJE_00588 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HPCKIGJE_00589 2.5e-21
HPCKIGJE_00590 3.8e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPCKIGJE_00592 3.5e-07 U protein secretion
HPCKIGJE_00593 2.7e-50 U protein secretion
HPCKIGJE_00595 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HPCKIGJE_00596 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HPCKIGJE_00597 4.9e-21 XK27_13030
HPCKIGJE_00598 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPCKIGJE_00599 9.2e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HPCKIGJE_00600 1.4e-69 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HPCKIGJE_00601 8e-165 S Protein of unknown function (DUF3114)
HPCKIGJE_00602 1.2e-22 S Protein of unknown function (DUF3114)
HPCKIGJE_00603 1.5e-118 yqfA K protein, Hemolysin III
HPCKIGJE_00604 1e-25 K hmm pf08876
HPCKIGJE_00605 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HPCKIGJE_00606 1.1e-217 mvaS 2.3.3.10 I synthase
HPCKIGJE_00607 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPCKIGJE_00608 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPCKIGJE_00609 9.7e-22
HPCKIGJE_00610 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPCKIGJE_00611 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HPCKIGJE_00612 1.5e-250 mmuP E amino acid
HPCKIGJE_00613 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HPCKIGJE_00614 1.4e-29 S Domain of unknown function (DUF1912)
HPCKIGJE_00615 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
HPCKIGJE_00616 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPCKIGJE_00617 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPCKIGJE_00618 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPCKIGJE_00619 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HPCKIGJE_00620 4.8e-16 S Protein of unknown function (DUF2969)
HPCKIGJE_00623 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
HPCKIGJE_00626 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
HPCKIGJE_00627 8e-70 M Pfam SNARE associated Golgi protein
HPCKIGJE_00628 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
HPCKIGJE_00629 9.3e-59 S oxidoreductase
HPCKIGJE_00630 9.7e-66 S oxidoreductase
HPCKIGJE_00631 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
HPCKIGJE_00632 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HPCKIGJE_00633 0.0 clpE O Belongs to the ClpA ClpB family
HPCKIGJE_00634 6.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPCKIGJE_00635 1.3e-34 ykuJ S protein conserved in bacteria
HPCKIGJE_00636 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HPCKIGJE_00637 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_00638 1.1e-78 feoA P FeoA domain protein
HPCKIGJE_00639 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HPCKIGJE_00640 1.5e-07
HPCKIGJE_00641 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPCKIGJE_00642 2.2e-45 K sequence-specific DNA binding
HPCKIGJE_00643 1.5e-35 yugF I carboxylic ester hydrolase activity
HPCKIGJE_00644 7.5e-23 I Alpha/beta hydrolase family
HPCKIGJE_00645 7.9e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPCKIGJE_00646 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPCKIGJE_00647 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HPCKIGJE_00648 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPCKIGJE_00649 5.8e-64 licT K transcriptional antiterminator
HPCKIGJE_00650 6.8e-53 licT K transcriptional antiterminator
HPCKIGJE_00651 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPCKIGJE_00652 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HPCKIGJE_00653 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPCKIGJE_00654 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPCKIGJE_00655 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPCKIGJE_00656 2.5e-220 mdtG EGP Major facilitator Superfamily
HPCKIGJE_00657 2e-33 secG U Preprotein translocase subunit SecG
HPCKIGJE_00658 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPCKIGJE_00659 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPCKIGJE_00660 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPCKIGJE_00661 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HPCKIGJE_00662 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HPCKIGJE_00663 4.4e-183 ccpA K Catabolite control protein A
HPCKIGJE_00664 2.8e-28 yyaQ S YjbR
HPCKIGJE_00665 6.6e-101 yyaQ V Protein conserved in bacteria
HPCKIGJE_00666 3.2e-92 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPCKIGJE_00667 5.5e-107 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPCKIGJE_00668 1e-78 yueI S Protein of unknown function (DUF1694)
HPCKIGJE_00669 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPCKIGJE_00670 2e-25 WQ51_00785
HPCKIGJE_00671 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HPCKIGJE_00672 2e-219 ywbD 2.1.1.191 J Methyltransferase
HPCKIGJE_00673 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HPCKIGJE_00674 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPCKIGJE_00675 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPCKIGJE_00676 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPCKIGJE_00677 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HPCKIGJE_00678 3.2e-53 yheA S Belongs to the UPF0342 family
HPCKIGJE_00679 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPCKIGJE_00680 5.8e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPCKIGJE_00681 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPCKIGJE_00682 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
HPCKIGJE_00683 2.6e-253 msrR K Transcriptional regulator
HPCKIGJE_00684 5e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
HPCKIGJE_00685 2.4e-203 I acyl-CoA dehydrogenase
HPCKIGJE_00686 4.5e-97 mip S hydroperoxide reductase activity
HPCKIGJE_00687 6.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPCKIGJE_00688 2e-104
HPCKIGJE_00689 1e-31 K Cro/C1-type HTH DNA-binding domain
HPCKIGJE_00690 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HPCKIGJE_00691 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
HPCKIGJE_00692 1.6e-95
HPCKIGJE_00693 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HPCKIGJE_00694 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_00695 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_00696 1e-185 S CRISPR-associated protein Csn2 subfamily St
HPCKIGJE_00697 2.7e-146 ycgQ S TIGR03943 family
HPCKIGJE_00698 1.2e-155 XK27_03015 S permease
HPCKIGJE_00700 0.0 yhgF K Transcriptional accessory protein
HPCKIGJE_00701 9.9e-42 pspC KT PspC domain
HPCKIGJE_00702 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPCKIGJE_00703 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPCKIGJE_00705 5.5e-69 ytxH S General stress protein
HPCKIGJE_00707 2e-177 yegQ O Peptidase U32
HPCKIGJE_00708 3.4e-252 yegQ O Peptidase U32
HPCKIGJE_00709 8.1e-46 S CHY zinc finger
HPCKIGJE_00710 8.4e-88 bioY S biotin synthase
HPCKIGJE_00712 1.1e-33 XK27_12190 S protein conserved in bacteria
HPCKIGJE_00713 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
HPCKIGJE_00714 4.8e-11
HPCKIGJE_00715 4.6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HPCKIGJE_00716 4.1e-225 mutH L DNA mismatch repair enzyme MutH
HPCKIGJE_00717 5.2e-29 S SIR2-like domain
HPCKIGJE_00718 1.2e-33 S SIR2-like domain
HPCKIGJE_00719 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPCKIGJE_00720 1.1e-159 M LysM domain
HPCKIGJE_00721 7.6e-16
HPCKIGJE_00722 2.3e-175 S hydrolase
HPCKIGJE_00723 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HPCKIGJE_00724 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPCKIGJE_00725 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HPCKIGJE_00726 2.7e-27 P Hemerythrin HHE cation binding domain protein
HPCKIGJE_00727 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HPCKIGJE_00728 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
HPCKIGJE_00729 4.7e-23 MA20_36090 S Protein of unknown function (DUF2974)
HPCKIGJE_00730 9e-96 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPCKIGJE_00731 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HPCKIGJE_00732 3.9e-159 S Bacteriophage abortive infection AbiH
HPCKIGJE_00734 1.4e-130 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HPCKIGJE_00735 3.6e-56 S Phage derived protein Gp49-like (DUF891)
HPCKIGJE_00736 5e-42 K Helix-turn-helix domain
HPCKIGJE_00737 8.9e-303 hsdM 2.1.1.72 V type I restriction-modification system
HPCKIGJE_00738 2.3e-48 S double-stranded DNA endodeoxyribonuclease activity
HPCKIGJE_00739 6.3e-21 spd F DNA RNA non-specific endonuclease
HPCKIGJE_00740 1.5e-125 spd F DNA RNA non-specific endonuclease
HPCKIGJE_00741 5e-91 lemA S LemA family
HPCKIGJE_00742 9.3e-132 htpX O Belongs to the peptidase M48B family
HPCKIGJE_00743 4.2e-75 S Psort location CytoplasmicMembrane, score
HPCKIGJE_00744 6.2e-56 S Domain of unknown function (DUF4430)
HPCKIGJE_00745 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPCKIGJE_00746 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
HPCKIGJE_00747 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HPCKIGJE_00748 2.7e-160 L Transposase
HPCKIGJE_00749 3e-50 L Transposase
HPCKIGJE_00750 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HPCKIGJE_00751 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPCKIGJE_00752 3.2e-92 dps P Belongs to the Dps family
HPCKIGJE_00753 9.5e-94 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HPCKIGJE_00754 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPCKIGJE_00755 3.5e-91 dps P Belongs to the Dps family
HPCKIGJE_00756 1.1e-80 perR P Belongs to the Fur family
HPCKIGJE_00757 8.4e-28 yqgQ S protein conserved in bacteria
HPCKIGJE_00758 2.2e-179 glk 2.7.1.2 G Glucokinase
HPCKIGJE_00759 0.0 typA T GTP-binding protein TypA
HPCKIGJE_00761 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPCKIGJE_00762 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPCKIGJE_00763 3.1e-169 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPCKIGJE_00764 5.2e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPCKIGJE_00765 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPCKIGJE_00766 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPCKIGJE_00767 1.4e-96 sepF D cell septum assembly
HPCKIGJE_00768 2e-34 yggT D integral membrane protein
HPCKIGJE_00769 6.1e-143 ylmH T S4 RNA-binding domain
HPCKIGJE_00770 1.8e-135 divIVA D Cell division protein DivIVA
HPCKIGJE_00771 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPCKIGJE_00772 5.5e-30
HPCKIGJE_00773 8.4e-10
HPCKIGJE_00774 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
HPCKIGJE_00775 2e-45 rpmE2 J 50S ribosomal protein L31
HPCKIGJE_00776 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPCKIGJE_00777 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HPCKIGJE_00778 8.9e-155 gst O Glutathione S-transferase
HPCKIGJE_00779 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPCKIGJE_00780 4.5e-111 tdk 2.7.1.21 F thymidine kinase
HPCKIGJE_00781 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPCKIGJE_00782 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPCKIGJE_00783 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPCKIGJE_00784 1.2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPCKIGJE_00785 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HPCKIGJE_00786 8e-100 pvaA M lytic transglycosylase activity
HPCKIGJE_00787 0.0 yfiB1 V abc transporter atp-binding protein
HPCKIGJE_00788 0.0 XK27_10035 V abc transporter atp-binding protein
HPCKIGJE_00789 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
HPCKIGJE_00790 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPCKIGJE_00791 3.9e-237 dltB M Membrane protein involved in D-alanine export
HPCKIGJE_00792 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPCKIGJE_00793 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPCKIGJE_00794 7e-33 L Integrase core domain protein
HPCKIGJE_00795 9.6e-32 L transposition
HPCKIGJE_00796 6.5e-54 L transposition
HPCKIGJE_00797 7.7e-19 L transposase activity
HPCKIGJE_00798 0.0 3.6.3.8 P cation transport ATPase
HPCKIGJE_00799 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HPCKIGJE_00801 2.9e-12
HPCKIGJE_00803 4.3e-67 S Virulence-associated protein E
HPCKIGJE_00804 1.4e-129 KL Phage plasmid primase P4 family
HPCKIGJE_00805 3.1e-22
HPCKIGJE_00806 1.4e-13
HPCKIGJE_00810 1.4e-19 K Cro/C1-type HTH DNA-binding domain
HPCKIGJE_00811 4.8e-32 xre K transcriptional
HPCKIGJE_00812 5.8e-219 sip L Belongs to the 'phage' integrase family
HPCKIGJE_00814 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPCKIGJE_00815 7.3e-166 metF 1.5.1.20 E reductase
HPCKIGJE_00816 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HPCKIGJE_00817 1.4e-143
HPCKIGJE_00818 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HPCKIGJE_00819 5.3e-275 pelF GT4 M Domain of unknown function (DUF3492)
HPCKIGJE_00820 6.2e-186 pelG M Putative exopolysaccharide Exporter (EPS-E)
HPCKIGJE_00821 1.5e-211 cotH M CotH kinase protein
HPCKIGJE_00822 7.1e-52 G Domain of unknown function (DUF4832)
HPCKIGJE_00823 4.9e-21 G Domain of unknown function (DUF4832)
HPCKIGJE_00824 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPCKIGJE_00826 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPCKIGJE_00827 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
HPCKIGJE_00828 2.4e-124 endA F DNA RNA non-specific endonuclease
HPCKIGJE_00829 4.2e-110 tcyB_2 P ABC transporter (permease)
HPCKIGJE_00830 8e-115 gltJ P ABC transporter (Permease
HPCKIGJE_00831 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HPCKIGJE_00832 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_00833 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPCKIGJE_00834 1.5e-247 vicK 2.7.13.3 T Histidine kinase
HPCKIGJE_00835 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HPCKIGJE_00836 5e-35 F Protein of unknown function (DUF454)
HPCKIGJE_00837 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HPCKIGJE_00838 9.2e-147 yidA S hydrolases of the HAD superfamily
HPCKIGJE_00839 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
HPCKIGJE_00840 2.6e-67 ywiB S Domain of unknown function (DUF1934)
HPCKIGJE_00841 0.0 pacL 3.6.3.8 P cation transport ATPase
HPCKIGJE_00842 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HPCKIGJE_00843 4.3e-180 yjjH S Calcineurin-like phosphoesterase
HPCKIGJE_00844 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPCKIGJE_00845 3.7e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPCKIGJE_00846 2.5e-124 ftsE D cell division ATP-binding protein FtsE
HPCKIGJE_00847 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HPCKIGJE_00848 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HPCKIGJE_00849 5.2e-175 yubA S permease
HPCKIGJE_00850 4.9e-224 G COG0457 FOG TPR repeat
HPCKIGJE_00851 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPCKIGJE_00852 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPCKIGJE_00853 2.9e-90 ebsA S Family of unknown function (DUF5322)
HPCKIGJE_00854 3.9e-15 M LysM domain
HPCKIGJE_00855 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPCKIGJE_00856 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPCKIGJE_00857 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPCKIGJE_00858 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPCKIGJE_00859 5.8e-42 L Transposase
HPCKIGJE_00860 1.6e-24 L Transposase
HPCKIGJE_00861 1.7e-47 XK27_03610 K Gnat family
HPCKIGJE_00862 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPCKIGJE_00863 5.3e-275 pepV 3.5.1.18 E Dipeptidase
HPCKIGJE_00864 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPCKIGJE_00865 6.1e-22 V Glucan-binding protein C
HPCKIGJE_00867 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPCKIGJE_00868 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HPCKIGJE_00869 1.3e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HPCKIGJE_00870 1.7e-109 clcA_2 P chloride
HPCKIGJE_00871 1e-09 yfeJ 6.3.5.2 F glutamine amidotransferase
HPCKIGJE_00872 4.7e-78 yfeJ 6.3.5.2 F glutamine amidotransferase
HPCKIGJE_00873 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HPCKIGJE_00874 4.4e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HPCKIGJE_00875 2.5e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HPCKIGJE_00876 1.1e-103 cps4C M biosynthesis protein
HPCKIGJE_00877 1e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
HPCKIGJE_00878 5.5e-253 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HPCKIGJE_00879 4e-59 rgpAc GT4 M Domain of unknown function (DUF1972)
HPCKIGJE_00880 5.6e-80 lspL 5.1.3.6 M epimerase dehydratase
HPCKIGJE_00881 3.2e-36 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HPCKIGJE_00882 4.5e-200 glf 5.4.99.9 M UDP-galactopyranose mutase
HPCKIGJE_00883 4.4e-152 M Glycosyl transferases group 1
HPCKIGJE_00884 4.3e-39 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HPCKIGJE_00885 7.1e-31 M Psort location Cytoplasmic, score 8.87
HPCKIGJE_00886 3.6e-42 M Psort location Cytoplasmic, score 8.87
HPCKIGJE_00887 1.6e-100 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPCKIGJE_00888 2.2e-57 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPCKIGJE_00889 9.6e-38 rfbF GT2 S Glycosyl transferase family 2
HPCKIGJE_00890 2.8e-61 GT2 S Glycosyl transferase family 2
HPCKIGJE_00891 1.6e-28
HPCKIGJE_00892 1.8e-31 2.4.1.52 GT4 V Glycosyl transferase, family 2
HPCKIGJE_00893 6.3e-83 M Glycosyl transferase, family 2
HPCKIGJE_00895 8.9e-34 L Transposase DDE domain
HPCKIGJE_00896 2.2e-150 Dcc 3.1.3.1, 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.4.17.14, 3.6.1.45 G Phosphodiester glycosidase
HPCKIGJE_00897 9.6e-137 capM K Cell envelope-related transcriptional attenuator domain
HPCKIGJE_00898 1.9e-71 L COG2801 Transposase and inactivated derivatives
HPCKIGJE_00899 8.9e-127 tnp L DDE domain
HPCKIGJE_00900 1.7e-91 V VanZ like family
HPCKIGJE_00901 1.2e-167 L transposase, IS4 family
HPCKIGJE_00902 3.1e-78 L Transposase
HPCKIGJE_00903 1.5e-130 L Transposase
HPCKIGJE_00904 6.6e-241 cps1C S Polysaccharide biosynthesis protein
HPCKIGJE_00905 6.9e-40 2.4.1.166 GT2 M Glycosyltransferase like family 2
HPCKIGJE_00906 1.9e-71 L COG2801 Transposase and inactivated derivatives
HPCKIGJE_00907 9.5e-37 L transposase helper protein for IS981
HPCKIGJE_00908 1.1e-32 M transferase activity, transferring glycosyl groups
HPCKIGJE_00910 4e-117 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HPCKIGJE_00911 1.5e-35 G alpha-ribazole phosphatase activity
HPCKIGJE_00912 7.5e-30 G Belongs to the phosphoglycerate mutase family
HPCKIGJE_00913 1.3e-199 S hmm pf01594
HPCKIGJE_00914 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HPCKIGJE_00915 8.4e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPCKIGJE_00916 4.2e-42 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HPCKIGJE_00917 4.9e-39 S granule-associated protein
HPCKIGJE_00918 3.7e-293 S unusual protein kinase
HPCKIGJE_00919 2.6e-15 estA E Lysophospholipase L1 and related esterases
HPCKIGJE_00920 3.9e-78 estA E GDSL-like protein
HPCKIGJE_00921 1.1e-158 rssA S Phospholipase, patatin family
HPCKIGJE_00922 1.1e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPCKIGJE_00923 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPCKIGJE_00924 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPCKIGJE_00925 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_00926 5e-38 P membrane protein (DUF2207)
HPCKIGJE_00927 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HPCKIGJE_00928 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HPCKIGJE_00929 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPCKIGJE_00930 0.0 lpdA 1.8.1.4 C Dehydrogenase
HPCKIGJE_00931 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HPCKIGJE_00932 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HPCKIGJE_00933 8.5e-266 3.5.1.28 NU amidase activity
HPCKIGJE_00934 1.9e-37 3.5.1.28 NU amidase activity
HPCKIGJE_00935 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_00936 1.2e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_00937 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_00938 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_00939 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_00940 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
HPCKIGJE_00941 5.6e-233 ycdB P peroxidase
HPCKIGJE_00942 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HPCKIGJE_00943 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPCKIGJE_00944 4.6e-25 tatA U protein secretion
HPCKIGJE_00945 2.3e-23 L Transposase
HPCKIGJE_00946 1.3e-303 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HPCKIGJE_00947 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPCKIGJE_00948 3.7e-09
HPCKIGJE_00949 1.1e-17
HPCKIGJE_00950 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
HPCKIGJE_00951 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HPCKIGJE_00952 0.0 pepN 3.4.11.2 E aminopeptidase
HPCKIGJE_00953 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
HPCKIGJE_00954 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPCKIGJE_00955 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPCKIGJE_00956 1.2e-155 pstA P phosphate transport system permease
HPCKIGJE_00957 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HPCKIGJE_00958 3.3e-158 pstS P phosphate
HPCKIGJE_00959 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HPCKIGJE_00960 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HPCKIGJE_00961 1.9e-43 yktA S Belongs to the UPF0223 family
HPCKIGJE_00962 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPCKIGJE_00963 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPCKIGJE_00964 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPCKIGJE_00965 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
HPCKIGJE_00966 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
HPCKIGJE_00967 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HPCKIGJE_00968 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPCKIGJE_00969 9.3e-62 S haloacid dehalogenase-like hydrolase
HPCKIGJE_00970 1.8e-59 Q phosphatase activity
HPCKIGJE_00971 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
HPCKIGJE_00972 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPCKIGJE_00973 1.8e-240 agcS E (Alanine) symporter
HPCKIGJE_00974 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPCKIGJE_00975 9.3e-239 L Transposase
HPCKIGJE_00976 1.4e-104 yfiF3 K sequence-specific DNA binding
HPCKIGJE_00977 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HPCKIGJE_00978 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HPCKIGJE_00980 1.8e-67 yecS P ABC transporter (Permease
HPCKIGJE_00981 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
HPCKIGJE_00982 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
HPCKIGJE_00983 1.1e-267 dtpT E transporter
HPCKIGJE_00985 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
HPCKIGJE_00986 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPCKIGJE_00987 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPCKIGJE_00988 5.2e-74 csm6 S Psort location Cytoplasmic, score
HPCKIGJE_00989 2.1e-14 csm6 S Psort location Cytoplasmic, score
HPCKIGJE_00990 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
HPCKIGJE_00991 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
HPCKIGJE_00992 1.1e-116 csm3 L RAMP superfamily
HPCKIGJE_00993 5.6e-62 csm2 L Pfam:DUF310
HPCKIGJE_00994 0.0 csm1 S CRISPR-associated protein Csm1 family
HPCKIGJE_00995 6.8e-133 cas6 S Pfam:DUF2276
HPCKIGJE_00996 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_00997 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_00998 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPCKIGJE_00999 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HPCKIGJE_01000 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HPCKIGJE_01001 5.7e-118 S TraX protein
HPCKIGJE_01003 3.5e-28 3.4.13.21 I Protein conserved in bacteria
HPCKIGJE_01004 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
HPCKIGJE_01005 3.7e-190
HPCKIGJE_01006 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HPCKIGJE_01008 4.8e-41 dinF V Mate efflux family protein
HPCKIGJE_01009 6.6e-73 dinF V Mate efflux family protein
HPCKIGJE_01010 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
HPCKIGJE_01011 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
HPCKIGJE_01012 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HPCKIGJE_01013 1.2e-143 2.4.2.3 F Phosphorylase superfamily
HPCKIGJE_01016 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
HPCKIGJE_01017 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
HPCKIGJE_01018 6e-08 S Hydrolases of the alpha beta superfamily
HPCKIGJE_01019 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HPCKIGJE_01020 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HPCKIGJE_01021 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HPCKIGJE_01022 1.8e-159 czcD P cation diffusion facilitator family transporter
HPCKIGJE_01023 4.5e-97 K Transcriptional regulator, TetR family
HPCKIGJE_01024 1.6e-10
HPCKIGJE_01025 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HPCKIGJE_01026 2.7e-116 V ABC transporter (Permease
HPCKIGJE_01027 8.1e-228 L the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01028 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HPCKIGJE_01029 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HPCKIGJE_01030 6.6e-61 EGP Major facilitator Superfamily
HPCKIGJE_01031 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HPCKIGJE_01032 1.1e-212 pqqE C radical SAM domain protein
HPCKIGJE_01035 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HPCKIGJE_01036 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPCKIGJE_01037 3.9e-19 IQ Acetoin reductase
HPCKIGJE_01038 5.8e-50 IQ Acetoin reductase
HPCKIGJE_01039 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPCKIGJE_01040 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HPCKIGJE_01041 7.5e-21 XK27_05470 E Methionine synthase
HPCKIGJE_01042 3.2e-152 XK27_05470 E Methionine synthase
HPCKIGJE_01043 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPCKIGJE_01044 4.3e-253 T PhoQ Sensor
HPCKIGJE_01045 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPCKIGJE_01046 5.1e-153 S TraX protein
HPCKIGJE_01047 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPCKIGJE_01048 8.3e-159 dprA LU DNA protecting protein DprA
HPCKIGJE_01049 4.1e-167 GK ROK family
HPCKIGJE_01050 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPCKIGJE_01051 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPCKIGJE_01052 6.9e-127 K DNA-binding helix-turn-helix protein
HPCKIGJE_01053 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
HPCKIGJE_01054 4.1e-87 niaX
HPCKIGJE_01055 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPCKIGJE_01056 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPCKIGJE_01057 4.5e-126 gntR1 K transcriptional
HPCKIGJE_01058 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPCKIGJE_01059 2.8e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HPCKIGJE_01060 1.1e-105 adhP 1.1.1.1 C alcohol dehydrogenase
HPCKIGJE_01061 3.4e-33 adhP 1.1.1.1 C alcohol dehydrogenase
HPCKIGJE_01062 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPCKIGJE_01063 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPCKIGJE_01064 1.1e-158 aatB ET ABC transporter substrate-binding protein
HPCKIGJE_01065 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_01066 2e-104 artQ P ABC transporter (Permease
HPCKIGJE_01067 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
HPCKIGJE_01068 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPCKIGJE_01069 2.6e-166 cpsY K Transcriptional regulator
HPCKIGJE_01070 1.9e-83 L transposition
HPCKIGJE_01071 5.5e-119 mur1 NU muramidase
HPCKIGJE_01072 1.2e-172 yeiH S Membrane
HPCKIGJE_01073 1.7e-08
HPCKIGJE_01074 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
HPCKIGJE_01075 2.2e-101 XK27_10720 D peptidase activity
HPCKIGJE_01076 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HPCKIGJE_01077 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
HPCKIGJE_01078 3.7e-157 glcU U Glucose uptake
HPCKIGJE_01079 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
HPCKIGJE_01080 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HPCKIGJE_01081 1.2e-88 L Transposase
HPCKIGJE_01082 2.2e-63 L Transposase
HPCKIGJE_01083 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HPCKIGJE_01084 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HPCKIGJE_01085 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HPCKIGJE_01086 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HPCKIGJE_01087 3.9e-223 L Transposase
HPCKIGJE_01088 0.0 copB 3.6.3.4 P E1-E2 ATPase
HPCKIGJE_01089 1.2e-61 L Transposase
HPCKIGJE_01090 5.7e-109 L Transposase
HPCKIGJE_01091 8e-42 K Cold-Shock Protein
HPCKIGJE_01092 5.4e-32 cspD K Cold shock protein domain
HPCKIGJE_01093 6.4e-168 pepD E Dipeptidase
HPCKIGJE_01094 8.7e-162 whiA K May be required for sporulation
HPCKIGJE_01095 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPCKIGJE_01096 1.2e-163 rapZ S Displays ATPase and GTPase activities
HPCKIGJE_01097 2.8e-137 yejC S cyclic nucleotide-binding protein
HPCKIGJE_01098 2.2e-19 D nuclear chromosome segregation
HPCKIGJE_01099 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HPCKIGJE_01100 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HPCKIGJE_01101 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
HPCKIGJE_01102 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HPCKIGJE_01103 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HPCKIGJE_01104 3e-13
HPCKIGJE_01105 2.4e-30
HPCKIGJE_01106 4.5e-17
HPCKIGJE_01107 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HPCKIGJE_01108 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HPCKIGJE_01109 3.1e-81 ypmB S Protein conserved in bacteria
HPCKIGJE_01110 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPCKIGJE_01111 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HPCKIGJE_01112 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HPCKIGJE_01113 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
HPCKIGJE_01114 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HPCKIGJE_01115 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HPCKIGJE_01116 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HPCKIGJE_01117 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPCKIGJE_01118 2.9e-30 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPCKIGJE_01119 7.2e-95 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HPCKIGJE_01120 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HPCKIGJE_01121 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HPCKIGJE_01122 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
HPCKIGJE_01123 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HPCKIGJE_01124 2.1e-30 rpsT J rRNA binding
HPCKIGJE_01125 2e-163 L Integrase core domain protein
HPCKIGJE_01126 1.1e-82 L Helix-turn-helix domain
HPCKIGJE_01127 1.9e-21 L Helix-turn-helix domain
HPCKIGJE_01128 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
HPCKIGJE_01129 3.1e-268 clcA P Chloride transporter, ClC family
HPCKIGJE_01130 3.7e-145 potD P spermidine putrescine ABC transporter
HPCKIGJE_01131 2.5e-39 potD P spermidine putrescine ABC transporter
HPCKIGJE_01132 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
HPCKIGJE_01133 1.1e-220 L Transposase
HPCKIGJE_01134 1.2e-165 L integrase core domain
HPCKIGJE_01135 3.9e-122 L Transposase
HPCKIGJE_01136 3.6e-88 T PhoQ Sensor
HPCKIGJE_01137 2.2e-43 T PhoQ Sensor
HPCKIGJE_01138 2.8e-40 T PhoQ Sensor
HPCKIGJE_01139 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPCKIGJE_01140 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPCKIGJE_01141 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HPCKIGJE_01142 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPCKIGJE_01143 4.1e-93 panT S ECF transporter, substrate-specific component
HPCKIGJE_01144 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HPCKIGJE_01145 3.2e-80 L Transposase
HPCKIGJE_01146 8.2e-111 L Transposase
HPCKIGJE_01147 4.3e-222 L Transposase
HPCKIGJE_01148 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPCKIGJE_01149 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPCKIGJE_01150 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPCKIGJE_01151 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HPCKIGJE_01152 2.7e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPCKIGJE_01153 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
HPCKIGJE_01155 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPCKIGJE_01156 8e-219 XK27_05110 P chloride
HPCKIGJE_01157 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HPCKIGJE_01158 1.3e-282 clcA P Chloride transporter, ClC family
HPCKIGJE_01159 2.3e-75 fld C Flavodoxin
HPCKIGJE_01160 5.5e-14 XK27_08880
HPCKIGJE_01161 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HPCKIGJE_01162 2.7e-151 estA CE1 S Putative esterase
HPCKIGJE_01163 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPCKIGJE_01164 4.4e-135 XK27_08845 S abc transporter atp-binding protein
HPCKIGJE_01165 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HPCKIGJE_01166 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
HPCKIGJE_01167 3.2e-17 S Domain of unknown function (DUF4649)
HPCKIGJE_01169 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01170 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01172 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01173 8.8e-223 L Transposase
HPCKIGJE_01175 1.8e-243 L Transposase
HPCKIGJE_01176 1.6e-249 L Transposase
HPCKIGJE_01177 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPCKIGJE_01178 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPCKIGJE_01179 0.0 dnaE 2.7.7.7 L DNA polymerase
HPCKIGJE_01180 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HPCKIGJE_01181 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPCKIGJE_01182 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPCKIGJE_01183 1.3e-42 ysdA L Membrane
HPCKIGJE_01184 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPCKIGJE_01185 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPCKIGJE_01186 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPCKIGJE_01187 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HPCKIGJE_01189 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPCKIGJE_01190 6.6e-83 ypmS S Protein conserved in bacteria
HPCKIGJE_01191 6e-144 ypmR E lipolytic protein G-D-S-L family
HPCKIGJE_01192 1e-148 DegV S DegV family
HPCKIGJE_01193 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
HPCKIGJE_01194 1.8e-72 argR K Regulates arginine biosynthesis genes
HPCKIGJE_01195 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPCKIGJE_01196 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPCKIGJE_01197 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HPCKIGJE_01198 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPCKIGJE_01201 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPCKIGJE_01202 2.9e-125 dnaD
HPCKIGJE_01203 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPCKIGJE_01204 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPCKIGJE_01205 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HPCKIGJE_01206 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPCKIGJE_01207 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPCKIGJE_01208 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HPCKIGJE_01209 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPCKIGJE_01210 1.6e-239 rodA D Belongs to the SEDS family
HPCKIGJE_01211 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HPCKIGJE_01212 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPCKIGJE_01213 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPCKIGJE_01214 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPCKIGJE_01215 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPCKIGJE_01216 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HPCKIGJE_01217 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPCKIGJE_01218 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPCKIGJE_01219 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPCKIGJE_01220 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPCKIGJE_01222 8.1e-29 L Integrase core domain protein
HPCKIGJE_01223 1.8e-44 L Integrase core domain protein
HPCKIGJE_01224 5.3e-56 L transposition
HPCKIGJE_01225 7.4e-23 L Transposase
HPCKIGJE_01226 1.6e-14 L transposase activity
HPCKIGJE_01227 1.3e-22 XK27_08085
HPCKIGJE_01228 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HPCKIGJE_01229 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HPCKIGJE_01230 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HPCKIGJE_01231 1.1e-121 ylfI S tigr01906
HPCKIGJE_01232 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPCKIGJE_01233 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
HPCKIGJE_01234 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HPCKIGJE_01236 9.3e-239 L Transposase
HPCKIGJE_01237 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPCKIGJE_01238 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPCKIGJE_01239 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPCKIGJE_01240 1.1e-206 yurR 1.4.5.1 E oxidoreductase
HPCKIGJE_01241 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
HPCKIGJE_01242 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPCKIGJE_01243 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPCKIGJE_01244 1.7e-70 gtrA S GtrA-like protein
HPCKIGJE_01245 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPCKIGJE_01246 6e-169 ybbR S Protein conserved in bacteria
HPCKIGJE_01247 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPCKIGJE_01248 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HPCKIGJE_01249 8.7e-150 cobQ S glutamine amidotransferase
HPCKIGJE_01250 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPCKIGJE_01251 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HPCKIGJE_01252 0.0 uup S abc transporter atp-binding protein
HPCKIGJE_01253 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HPCKIGJE_01254 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPCKIGJE_01255 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPCKIGJE_01256 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HPCKIGJE_01257 1.6e-249 L Transposase
HPCKIGJE_01258 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPCKIGJE_01259 7.9e-39 ptsH G phosphocarrier protein Hpr
HPCKIGJE_01260 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
HPCKIGJE_01261 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
HPCKIGJE_01262 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HPCKIGJE_01263 2.2e-34 nrdH O Glutaredoxin
HPCKIGJE_01264 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPCKIGJE_01265 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPCKIGJE_01267 4e-38 L Transposase (IS116 IS110 IS902 family)
HPCKIGJE_01268 5.1e-27 L Transposase (IS116 IS110 IS902 family)
HPCKIGJE_01269 2e-164 ypuA S secreted protein
HPCKIGJE_01270 8.3e-51 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
HPCKIGJE_01271 2.1e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HPCKIGJE_01272 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPCKIGJE_01273 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPCKIGJE_01274 3.4e-258 noxE P NADH oxidase
HPCKIGJE_01275 1.9e-294 yfmM S abc transporter atp-binding protein
HPCKIGJE_01276 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HPCKIGJE_01277 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HPCKIGJE_01278 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HPCKIGJE_01279 2e-86 S ECF-type riboflavin transporter, S component
HPCKIGJE_01281 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HPCKIGJE_01282 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HPCKIGJE_01285 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPCKIGJE_01286 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPCKIGJE_01287 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPCKIGJE_01288 0.0 smc D Required for chromosome condensation and partitioning
HPCKIGJE_01289 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPCKIGJE_01290 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPCKIGJE_01291 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPCKIGJE_01292 1.2e-91 pat 2.3.1.183 M acetyltransferase
HPCKIGJE_01293 1.1e-12
HPCKIGJE_01294 8.9e-30
HPCKIGJE_01295 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPCKIGJE_01296 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPCKIGJE_01297 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HPCKIGJE_01298 2e-88 proW P Binding-protein-dependent transport system inner membrane component
HPCKIGJE_01299 1.6e-137 proV E abc transporter atp-binding protein
HPCKIGJE_01300 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
HPCKIGJE_01301 4.3e-102 proWZ P ABC transporter (Permease
HPCKIGJE_01302 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
HPCKIGJE_01303 1.6e-205 S Protein of unknown function (DUF917)
HPCKIGJE_01304 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HPCKIGJE_01305 1.4e-121 sdaAB 4.3.1.17 E L-serine dehydratase
HPCKIGJE_01306 2.4e-29 sdaAA 4.3.1.17 E L-serine dehydratase
HPCKIGJE_01307 6.3e-103 sdaAA 4.3.1.17 E L-serine dehydratase
HPCKIGJE_01308 7.4e-26
HPCKIGJE_01309 1.1e-144 S ABC-2 family transporter protein
HPCKIGJE_01310 3.6e-97 S transport system, permease component
HPCKIGJE_01311 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HPCKIGJE_01312 5.7e-192 desK 2.7.13.3 T Histidine kinase
HPCKIGJE_01313 1.4e-133 yvfS V ABC-2 type transporter
HPCKIGJE_01314 9.7e-158 XK27_09825 V abc transporter atp-binding protein
HPCKIGJE_01317 3.6e-163 yocS S Transporter
HPCKIGJE_01318 3.1e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HPCKIGJE_01319 7.5e-115 yvfS V Transporter
HPCKIGJE_01320 2.7e-152 XK27_09825 V abc transporter atp-binding protein
HPCKIGJE_01321 2.7e-14 liaI KT membrane
HPCKIGJE_01322 2.6e-30 liaI KT membrane
HPCKIGJE_01323 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
HPCKIGJE_01324 0.0 V ABC transporter (permease)
HPCKIGJE_01325 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HPCKIGJE_01326 6.2e-166 T Histidine kinase
HPCKIGJE_01327 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPCKIGJE_01328 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPCKIGJE_01329 3.3e-69 pbuX F xanthine permease
HPCKIGJE_01330 9.2e-119 pbuX F xanthine permease
HPCKIGJE_01331 1.5e-247 norM V Multidrug efflux pump
HPCKIGJE_01332 9e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPCKIGJE_01333 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
HPCKIGJE_01334 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPCKIGJE_01335 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPCKIGJE_01336 4.8e-25 csbD K CsbD-like
HPCKIGJE_01337 6.2e-228 yfnA E amino acid
HPCKIGJE_01338 5.1e-110 XK27_02070 S nitroreductase
HPCKIGJE_01339 9.5e-150 1.13.11.2 S glyoxalase
HPCKIGJE_01340 5.6e-77 ywnA K Transcriptional regulator
HPCKIGJE_01341 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
HPCKIGJE_01342 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPCKIGJE_01343 1.4e-110 drgA C Nitroreductase
HPCKIGJE_01344 3e-102 yoaK S Protein of unknown function (DUF1275)
HPCKIGJE_01346 6.8e-161 yvgN C reductase
HPCKIGJE_01347 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPCKIGJE_01348 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
HPCKIGJE_01350 1.1e-37 BP1961 P nitric oxide dioxygenase activity
HPCKIGJE_01351 1.4e-54 K response regulator
HPCKIGJE_01352 2.1e-71 S Signal peptide protein, YSIRK family
HPCKIGJE_01353 1e-60
HPCKIGJE_01354 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPCKIGJE_01355 1e-137
HPCKIGJE_01356 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
HPCKIGJE_01357 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
HPCKIGJE_01358 5.8e-109 MA20_06410 E LysE type translocator
HPCKIGJE_01359 5.6e-08
HPCKIGJE_01360 2.7e-09
HPCKIGJE_01361 0.0 M family 8
HPCKIGJE_01363 1.5e-162 hrtB V MacB-like periplasmic core domain
HPCKIGJE_01364 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
HPCKIGJE_01365 1.1e-151 V MatE
HPCKIGJE_01367 3.9e-110 C Fe-S oxidoreductases
HPCKIGJE_01368 1.2e-176 EGP Major Facilitator Superfamily
HPCKIGJE_01369 5.5e-258 I radical SAM domain protein
HPCKIGJE_01371 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HPCKIGJE_01372 1.4e-150 L Integrase core domain protein
HPCKIGJE_01373 1.8e-87 L transposase activity
HPCKIGJE_01375 2.8e-85
HPCKIGJE_01376 0.0 sbcC L ATPase involved in DNA repair
HPCKIGJE_01377 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPCKIGJE_01378 0.0 lacL 3.2.1.23 G -beta-galactosidase
HPCKIGJE_01379 0.0 lacS G transporter
HPCKIGJE_01380 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPCKIGJE_01381 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPCKIGJE_01382 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HPCKIGJE_01383 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPCKIGJE_01384 2.3e-184 galR K Transcriptional regulator
HPCKIGJE_01385 2.7e-08 L Integrase core domain protein
HPCKIGJE_01386 1.2e-25 L transposition
HPCKIGJE_01387 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HPCKIGJE_01388 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HPCKIGJE_01389 2.5e-101 V abc transporter atp-binding protein
HPCKIGJE_01390 4.3e-40 V abc transporter atp-binding protein
HPCKIGJE_01391 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HPCKIGJE_01392 6.4e-62 L Transposase
HPCKIGJE_01393 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_01394 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_01395 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HPCKIGJE_01396 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPCKIGJE_01397 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HPCKIGJE_01398 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPCKIGJE_01399 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPCKIGJE_01402 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HPCKIGJE_01403 1.7e-174 vraS 2.7.13.3 T Histidine kinase
HPCKIGJE_01404 9.1e-119 yvqF KT membrane
HPCKIGJE_01405 1.4e-104 prkC 2.7.11.1 KLT serine threonine protein kinase
HPCKIGJE_01406 1.3e-180 prkC 2.7.11.1 KLT serine threonine protein kinase
HPCKIGJE_01407 2.9e-131 stp 3.1.3.16 T phosphatase
HPCKIGJE_01408 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPCKIGJE_01409 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPCKIGJE_01410 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPCKIGJE_01411 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HPCKIGJE_01412 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HPCKIGJE_01413 2.2e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPCKIGJE_01414 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
HPCKIGJE_01415 6.3e-148 supH S overlaps another CDS with the same product name
HPCKIGJE_01416 8.6e-63 yvoA_1 K Transcriptional
HPCKIGJE_01417 2.8e-120 skfE V abc transporter atp-binding protein
HPCKIGJE_01418 1.6e-132 V ATPase activity
HPCKIGJE_01419 5.6e-172 oppF P Belongs to the ABC transporter superfamily
HPCKIGJE_01420 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HPCKIGJE_01421 4.9e-168 amiD P ABC transporter (Permease
HPCKIGJE_01422 4.2e-278 amiC P ABC transporter (Permease
HPCKIGJE_01423 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HPCKIGJE_01424 1.5e-65
HPCKIGJE_01425 1.1e-156 L Transposase
HPCKIGJE_01426 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HPCKIGJE_01427 8.1e-45 L Transposase
HPCKIGJE_01428 4.1e-158 L COG2801 Transposase and inactivated derivatives
HPCKIGJE_01429 1.2e-24 oppF P Belongs to the ABC transporter superfamily
HPCKIGJE_01430 3.5e-24 oppF P Belongs to the ABC transporter superfamily
HPCKIGJE_01431 8.9e-40 tatD L Hydrolase, tatd
HPCKIGJE_01432 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HPCKIGJE_01433 2.1e-85 L Integrase core domain protein
HPCKIGJE_01434 1.1e-23 L transposase activity
HPCKIGJE_01435 8.9e-18 L transposase activity
HPCKIGJE_01436 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPCKIGJE_01437 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HPCKIGJE_01438 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPCKIGJE_01439 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HPCKIGJE_01440 1.5e-103 yjbK S Adenylate cyclase
HPCKIGJE_01441 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPCKIGJE_01442 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
HPCKIGJE_01443 2e-58 XK27_04120 S Putative amino acid metabolism
HPCKIGJE_01444 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPCKIGJE_01445 1.1e-129 puuD T peptidase C26
HPCKIGJE_01446 2.4e-119 radC E Belongs to the UPF0758 family
HPCKIGJE_01447 0.0 rgpF M Rhamnan synthesis protein F
HPCKIGJE_01448 2.4e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HPCKIGJE_01449 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPCKIGJE_01450 2.8e-143 rgpC GM Transport permease protein
HPCKIGJE_01451 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
HPCKIGJE_01452 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
HPCKIGJE_01453 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
HPCKIGJE_01454 2.6e-220 amrA S polysaccharide biosynthetic process
HPCKIGJE_01455 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
HPCKIGJE_01456 7.6e-126 ycbB S Glycosyl transferase family 2
HPCKIGJE_01457 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPCKIGJE_01458 6.4e-246
HPCKIGJE_01459 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HPCKIGJE_01460 1.4e-251 M Psort location CytoplasmicMembrane, score
HPCKIGJE_01461 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HPCKIGJE_01462 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPCKIGJE_01463 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPCKIGJE_01464 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPCKIGJE_01465 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
HPCKIGJE_01466 1.4e-201 arcT 2.6.1.1 E Aminotransferase
HPCKIGJE_01467 2.5e-136 ET ABC transporter
HPCKIGJE_01468 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
HPCKIGJE_01469 2.9e-84 mutT 3.6.1.55 F Nudix family
HPCKIGJE_01470 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPCKIGJE_01471 1.5e-78 S CAAX amino terminal protease family protein
HPCKIGJE_01472 2.4e-33 S CAAX amino terminal protease family protein
HPCKIGJE_01473 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HPCKIGJE_01474 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_01475 2.4e-16 XK27_00735
HPCKIGJE_01476 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPCKIGJE_01478 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPCKIGJE_01481 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HPCKIGJE_01482 6.6e-30 ycaO O OsmC-like protein
HPCKIGJE_01484 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
HPCKIGJE_01486 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
HPCKIGJE_01487 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_01488 5.8e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPCKIGJE_01489 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HPCKIGJE_01490 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
HPCKIGJE_01491 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPCKIGJE_01492 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPCKIGJE_01493 2.6e-109 3.1.3.18 S IA, variant 1
HPCKIGJE_01494 2.2e-117 lrgB M effector of murein hydrolase
HPCKIGJE_01495 2.2e-58 lrgA S Effector of murein hydrolase LrgA
HPCKIGJE_01497 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HPCKIGJE_01498 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HPCKIGJE_01499 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPCKIGJE_01500 1.3e-104 wecD M Acetyltransferase (GNAT) domain
HPCKIGJE_01501 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPCKIGJE_01502 2.7e-97 GK ROK family
HPCKIGJE_01503 4e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
HPCKIGJE_01504 6.6e-47 XK27_08050 O stress-induced mitochondrial fusion
HPCKIGJE_01505 6.9e-23 XK27_08050 O HflC and HflK could regulate a protease
HPCKIGJE_01507 2.3e-206 potD P spermidine putrescine ABC transporter
HPCKIGJE_01508 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
HPCKIGJE_01509 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HPCKIGJE_01510 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPCKIGJE_01511 7.8e-171 murB 1.3.1.98 M cell wall formation
HPCKIGJE_01512 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPCKIGJE_01513 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPCKIGJE_01514 4.6e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HPCKIGJE_01515 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPCKIGJE_01516 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HPCKIGJE_01517 0.0 ydaO E amino acid
HPCKIGJE_01518 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPCKIGJE_01519 4.1e-37 ylqC L Belongs to the UPF0109 family
HPCKIGJE_01520 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPCKIGJE_01521 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HPCKIGJE_01523 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HPCKIGJE_01524 2.1e-74 S QueT transporter
HPCKIGJE_01525 1.9e-55 L Transposase
HPCKIGJE_01526 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HPCKIGJE_01527 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPCKIGJE_01528 3.7e-85 ccl S cog cog4708
HPCKIGJE_01529 7.4e-164 rbn E Belongs to the UPF0761 family
HPCKIGJE_01530 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HPCKIGJE_01531 3.3e-231 ytoI K transcriptional regulator containing CBS domains
HPCKIGJE_01532 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HPCKIGJE_01533 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPCKIGJE_01534 0.0 comEC S Competence protein ComEC
HPCKIGJE_01535 7.5e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HPCKIGJE_01536 1.3e-142 plsC 2.3.1.51 I Acyltransferase
HPCKIGJE_01537 1.7e-77 nodB3 G polysaccharide deacetylase
HPCKIGJE_01538 4.1e-22 nodB3 G polysaccharide deacetylase
HPCKIGJE_01539 2.3e-139 yabB 2.1.1.223 L Methyltransferase
HPCKIGJE_01540 1e-41 yazA L endonuclease containing a URI domain
HPCKIGJE_01541 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPCKIGJE_01542 2.3e-154 corA P CorA-like protein
HPCKIGJE_01543 1.9e-62 yjqA S Bacterial PH domain
HPCKIGJE_01544 7.8e-100 thiT S Thiamine transporter
HPCKIGJE_01545 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HPCKIGJE_01546 1.9e-201 yjbB G Permeases of the major facilitator superfamily
HPCKIGJE_01547 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPCKIGJE_01548 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
HPCKIGJE_01549 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPCKIGJE_01553 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HPCKIGJE_01554 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_01555 3e-106 P ABC transporter (Permease
HPCKIGJE_01556 6e-115 papP P ABC transporter (Permease
HPCKIGJE_01557 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPCKIGJE_01558 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HPCKIGJE_01559 0.0 copA 3.6.3.54 P P-type ATPase
HPCKIGJE_01560 2.7e-73 copY K Copper transport repressor, CopY TcrY family
HPCKIGJE_01561 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPCKIGJE_01562 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPCKIGJE_01563 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HPCKIGJE_01564 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HPCKIGJE_01565 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPCKIGJE_01566 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HPCKIGJE_01567 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPCKIGJE_01568 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HPCKIGJE_01569 3.2e-56
HPCKIGJE_01570 0.0 ctpE P E1-E2 ATPase
HPCKIGJE_01571 3.9e-26
HPCKIGJE_01572 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPCKIGJE_01573 9.7e-28 L transposase activity
HPCKIGJE_01574 2.7e-129 K transcriptional regulator, MerR family
HPCKIGJE_01575 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
HPCKIGJE_01576 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
HPCKIGJE_01577 4.8e-63 XK27_02560 S cog cog2151
HPCKIGJE_01578 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HPCKIGJE_01579 1.7e-226 ytfP S Flavoprotein
HPCKIGJE_01581 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPCKIGJE_01582 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HPCKIGJE_01583 2.7e-183 ecsB U ABC transporter
HPCKIGJE_01584 2.3e-133 ecsA V abc transporter atp-binding protein
HPCKIGJE_01585 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HPCKIGJE_01586 5.6e-12
HPCKIGJE_01587 2.6e-55 S CD20-like family
HPCKIGJE_01588 7.3e-107
HPCKIGJE_01589 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HPCKIGJE_01590 6.9e-206 ylbM S Belongs to the UPF0348 family
HPCKIGJE_01591 2e-140 yqeM Q Methyltransferase domain protein
HPCKIGJE_01592 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPCKIGJE_01593 5.2e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HPCKIGJE_01594 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPCKIGJE_01595 3.5e-49 yhbY J RNA-binding protein
HPCKIGJE_01596 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HPCKIGJE_01597 1.8e-98 yqeG S hydrolase of the HAD superfamily
HPCKIGJE_01598 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPCKIGJE_01599 1.2e-58
HPCKIGJE_01600 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPCKIGJE_01601 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPCKIGJE_01602 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPCKIGJE_01603 1.8e-23 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
HPCKIGJE_01604 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HPCKIGJE_01605 6.5e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPCKIGJE_01606 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPCKIGJE_01607 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPCKIGJE_01608 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
HPCKIGJE_01609 6.8e-101 pncA Q isochorismatase
HPCKIGJE_01610 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HPCKIGJE_01611 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HPCKIGJE_01612 2.4e-75 XK27_03180 T universal stress protein
HPCKIGJE_01615 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPCKIGJE_01616 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HPCKIGJE_01617 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HPCKIGJE_01618 0.0 yjcE P NhaP-type Na H and K H antiporters
HPCKIGJE_01620 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HPCKIGJE_01621 1.3e-184 yhcC S radical SAM protein
HPCKIGJE_01622 2.2e-196 ylbL T Belongs to the peptidase S16 family
HPCKIGJE_01623 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPCKIGJE_01624 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HPCKIGJE_01625 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPCKIGJE_01626 3.2e-09 S Protein of unknown function (DUF4059)
HPCKIGJE_01627 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
HPCKIGJE_01628 1e-162 yxeN P ABC transporter (Permease
HPCKIGJE_01629 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HPCKIGJE_01631 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPCKIGJE_01632 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HPCKIGJE_01633 5.2e-147 cah 4.2.1.1 P carbonic anhydrase
HPCKIGJE_01634 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPCKIGJE_01635 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HPCKIGJE_01636 2.9e-87 D nuclear chromosome segregation
HPCKIGJE_01637 1.5e-127 ybbM S transport system, permease component
HPCKIGJE_01638 1.2e-117 ybbL S abc transporter atp-binding protein
HPCKIGJE_01639 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HPCKIGJE_01640 4.6e-140 cppA E CppA N-terminal
HPCKIGJE_01641 5e-44 V CAAX protease self-immunity
HPCKIGJE_01642 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HPCKIGJE_01643 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPCKIGJE_01646 3e-47 spiA K sequence-specific DNA binding
HPCKIGJE_01647 2.9e-28 blpT
HPCKIGJE_01648 6.7e-98 blpT
HPCKIGJE_01649 3.9e-122 L Transposase
HPCKIGJE_01650 1.2e-165 L integrase core domain
HPCKIGJE_01655 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
HPCKIGJE_01658 7.4e-135 agrA KT phosphorelay signal transduction system
HPCKIGJE_01659 2.3e-235 blpH 2.7.13.3 T protein histidine kinase activity
HPCKIGJE_01661 7.3e-237 mesE M Transport protein ComB
HPCKIGJE_01662 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPCKIGJE_01663 0.0 mdlB V abc transporter atp-binding protein
HPCKIGJE_01664 3.5e-302 mdlA V abc transporter atp-binding protein
HPCKIGJE_01666 8.5e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
HPCKIGJE_01667 1.1e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPCKIGJE_01668 3.6e-70 yutD J protein conserved in bacteria
HPCKIGJE_01669 5.1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPCKIGJE_01671 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPCKIGJE_01672 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPCKIGJE_01673 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HPCKIGJE_01674 2.1e-46 ftsL D cell division protein FtsL
HPCKIGJE_01675 1e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPCKIGJE_01676 4.8e-93
HPCKIGJE_01677 7.5e-30
HPCKIGJE_01679 8.7e-33 yhaI J Protein of unknown function (DUF805)
HPCKIGJE_01680 1.3e-08 D nuclear chromosome segregation
HPCKIGJE_01681 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPCKIGJE_01682 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPCKIGJE_01683 2.2e-285 XK27_00765
HPCKIGJE_01684 5.2e-133 ecsA_2 V abc transporter atp-binding protein
HPCKIGJE_01685 5.2e-125 S Protein of unknown function (DUF554)
HPCKIGJE_01686 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPCKIGJE_01687 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HPCKIGJE_01688 2.6e-121 liaI S membrane
HPCKIGJE_01689 5.2e-75 XK27_02470 K LytTr DNA-binding domain
HPCKIGJE_01690 2.5e-67 KT response to antibiotic
HPCKIGJE_01691 1.7e-16 KT response to antibiotic
HPCKIGJE_01692 5.9e-54 yebC M Membrane
HPCKIGJE_01693 2.9e-18 yebC M Membrane
HPCKIGJE_01694 1.6e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HPCKIGJE_01695 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HPCKIGJE_01696 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPCKIGJE_01697 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPCKIGJE_01698 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPCKIGJE_01699 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPCKIGJE_01700 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPCKIGJE_01701 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPCKIGJE_01703 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPCKIGJE_01704 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HPCKIGJE_01705 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
HPCKIGJE_01706 5.4e-291 scrB 3.2.1.26 GH32 G invertase
HPCKIGJE_01707 7.5e-180 scrR K Transcriptional
HPCKIGJE_01708 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPCKIGJE_01709 3.4e-62 yqhY S protein conserved in bacteria
HPCKIGJE_01710 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPCKIGJE_01711 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
HPCKIGJE_01712 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HPCKIGJE_01714 8e-44 V 'abc transporter, ATP-binding protein
HPCKIGJE_01715 1e-58 V 'abc transporter, ATP-binding protein
HPCKIGJE_01718 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPCKIGJE_01719 5e-168 corA P COG0598 Mg2 and Co2 transporters
HPCKIGJE_01720 2e-123 XK27_01040 S Pfam PF06570
HPCKIGJE_01722 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPCKIGJE_01723 1e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPCKIGJE_01724 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HPCKIGJE_01725 3.6e-41 XK27_05745
HPCKIGJE_01726 9.5e-230 mutY L A G-specific adenine glycosylase
HPCKIGJE_01729 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPCKIGJE_01730 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPCKIGJE_01731 1e-93 cvpA S toxin biosynthetic process
HPCKIGJE_01732 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPCKIGJE_01733 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPCKIGJE_01734 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPCKIGJE_01735 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPCKIGJE_01736 2e-47 azlD E branched-chain amino acid
HPCKIGJE_01737 1.8e-114 azlC E AzlC protein
HPCKIGJE_01738 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPCKIGJE_01739 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPCKIGJE_01740 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HPCKIGJE_01741 2.5e-33 ykzG S Belongs to the UPF0356 family
HPCKIGJE_01742 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPCKIGJE_01743 2.7e-40 pscB M CHAP domain protein
HPCKIGJE_01744 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HPCKIGJE_01745 8.5e-63 glnR K Transcriptional regulator
HPCKIGJE_01746 1.3e-87 S Fusaric acid resistance protein-like
HPCKIGJE_01747 1.1e-12
HPCKIGJE_01748 8.9e-30
HPCKIGJE_01749 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPCKIGJE_01750 4.5e-36 L transposase activity
HPCKIGJE_01751 7.4e-23 L Transposase
HPCKIGJE_01752 5.3e-56 L transposition
HPCKIGJE_01753 1.8e-44 L Integrase core domain protein
HPCKIGJE_01754 4.2e-28 L Integrase core domain protein
HPCKIGJE_01755 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPCKIGJE_01756 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPCKIGJE_01757 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPCKIGJE_01758 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPCKIGJE_01759 1.6e-249 L Transposase
HPCKIGJE_01760 4.2e-142 purR 2.4.2.7 F operon repressor
HPCKIGJE_01761 4e-178 cbf S 3'-5' exoribonuclease yhaM
HPCKIGJE_01762 6.9e-173 rmuC S RmuC domain protein
HPCKIGJE_01763 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPCKIGJE_01764 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPCKIGJE_01765 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPCKIGJE_01767 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPCKIGJE_01768 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPCKIGJE_01769 1.6e-143 tatD L Hydrolase, tatd
HPCKIGJE_01770 7.2e-74 yccU S CoA-binding protein
HPCKIGJE_01771 4.8e-51 trxA O Belongs to the thioredoxin family
HPCKIGJE_01772 1.9e-141 S Macro domain protein
HPCKIGJE_01774 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
HPCKIGJE_01778 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPCKIGJE_01779 2.3e-33 L Transposase
HPCKIGJE_01780 1e-13 rpmH J Ribosomal protein L34
HPCKIGJE_01781 2e-186 jag S RNA-binding protein
HPCKIGJE_01782 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPCKIGJE_01783 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPCKIGJE_01784 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
HPCKIGJE_01785 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPCKIGJE_01786 6e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPCKIGJE_01787 2e-20 amiA E ABC transporter, substrate-binding protein, family 5
HPCKIGJE_01788 6.6e-63 amiA E transmembrane transport
HPCKIGJE_01789 4.2e-74 amiA E transmembrane transport
HPCKIGJE_01790 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPCKIGJE_01791 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPCKIGJE_01792 9.2e-51 S Protein of unknown function (DUF3397)
HPCKIGJE_01793 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HPCKIGJE_01794 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
HPCKIGJE_01795 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
HPCKIGJE_01796 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPCKIGJE_01797 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HPCKIGJE_01798 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
HPCKIGJE_01799 4.3e-77 XK27_09620 S reductase
HPCKIGJE_01800 9e-62 XK27_09615 C reductase
HPCKIGJE_01801 2.3e-141 XK27_09615 C reductase
HPCKIGJE_01802 3.2e-62 fnt P Formate nitrite transporter
HPCKIGJE_01803 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
HPCKIGJE_01804 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPCKIGJE_01805 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPCKIGJE_01806 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HPCKIGJE_01807 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPCKIGJE_01808 3.9e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPCKIGJE_01809 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPCKIGJE_01810 2.7e-48 S glycolate biosynthetic process
HPCKIGJE_01811 3.4e-64 S phosphatase activity
HPCKIGJE_01812 2e-157 rrmA 2.1.1.187 Q methyltransferase
HPCKIGJE_01815 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPCKIGJE_01816 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPCKIGJE_01817 6.4e-37 yeeD O sulfur carrier activity
HPCKIGJE_01818 1.3e-190 yeeE S Sulphur transport
HPCKIGJE_01819 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPCKIGJE_01820 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPCKIGJE_01821 3.2e-09 S Domain of unknown function (DUF4651)
HPCKIGJE_01822 7.5e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HPCKIGJE_01823 1.5e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPCKIGJE_01824 2.1e-109 S CAAX amino terminal protease family protein
HPCKIGJE_01826 4.1e-66 V CAAX protease self-immunity
HPCKIGJE_01827 2.6e-26 lanR K sequence-specific DNA binding
HPCKIGJE_01828 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPCKIGJE_01829 5.9e-177 ytxK 2.1.1.72 L DNA methylase
HPCKIGJE_01830 6.8e-13 comGF U Putative Competence protein ComGF
HPCKIGJE_01831 4e-72 comGF U Competence protein ComGF
HPCKIGJE_01832 1.4e-15 NU Type II secretory pathway pseudopilin
HPCKIGJE_01833 1.8e-57 cglD NU Competence protein
HPCKIGJE_01834 9.4e-42 comGC U Required for transformation and DNA binding
HPCKIGJE_01835 9.2e-153 cglB NU type II secretion system
HPCKIGJE_01836 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HPCKIGJE_01837 2.9e-68 S cog cog4699
HPCKIGJE_01838 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPCKIGJE_01839 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPCKIGJE_01840 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPCKIGJE_01841 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPCKIGJE_01842 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPCKIGJE_01843 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HPCKIGJE_01844 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HPCKIGJE_01845 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HPCKIGJE_01846 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HPCKIGJE_01847 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
HPCKIGJE_01848 1.4e-57 asp S cog cog1302
HPCKIGJE_01849 9.3e-226 norN V Mate efflux family protein
HPCKIGJE_01850 1.9e-278 thrC 4.2.3.1 E Threonine synthase
HPCKIGJE_01851 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPCKIGJE_01852 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
HPCKIGJE_01853 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPCKIGJE_01854 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPCKIGJE_01855 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HPCKIGJE_01856 0.0 pepO 3.4.24.71 O Peptidase family M13
HPCKIGJE_01857 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HPCKIGJE_01858 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HPCKIGJE_01859 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HPCKIGJE_01860 1.4e-54 treB 2.7.1.201 G PTS System
HPCKIGJE_01861 5.8e-21 treR K DNA-binding transcription factor activity
HPCKIGJE_01862 8.6e-87 treR K trehalose operon
HPCKIGJE_01863 3.3e-95 ywlG S Belongs to the UPF0340 family
HPCKIGJE_01866 2.7e-13 L PFAM Integrase, catalytic core
HPCKIGJE_01867 4.3e-77 L PFAM Integrase, catalytic core
HPCKIGJE_01868 3.3e-46 K Putative DNA-binding domain
HPCKIGJE_01869 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
HPCKIGJE_01870 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPCKIGJE_01871 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01876 1e-39
HPCKIGJE_01877 6.5e-31
HPCKIGJE_01878 1.3e-31 S Hypothetical protein (DUF2513)
HPCKIGJE_01879 7.7e-13
HPCKIGJE_01881 5.7e-217 S MvaI/BcnI restriction endonuclease family
HPCKIGJE_01883 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HPCKIGJE_01884 1.8e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
HPCKIGJE_01886 3e-110 6.3.2.2 H ergothioneine biosynthetic process
HPCKIGJE_01887 2.7e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
HPCKIGJE_01888 3.4e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HPCKIGJE_01889 1.9e-33 L PFAM Integrase, catalytic core
HPCKIGJE_01890 2.1e-115 L PFAM Integrase, catalytic core
HPCKIGJE_01891 3.3e-62 rplQ J ribosomal protein l17
HPCKIGJE_01892 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPCKIGJE_01893 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPCKIGJE_01894 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPCKIGJE_01895 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HPCKIGJE_01896 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPCKIGJE_01897 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPCKIGJE_01898 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPCKIGJE_01899 4.4e-58 rplO J binds to the 23S rRNA
HPCKIGJE_01900 2.5e-23 rpmD J ribosomal protein l30
HPCKIGJE_01901 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPCKIGJE_01902 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPCKIGJE_01903 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPCKIGJE_01904 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPCKIGJE_01905 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPCKIGJE_01906 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPCKIGJE_01907 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPCKIGJE_01908 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPCKIGJE_01909 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPCKIGJE_01910 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HPCKIGJE_01911 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPCKIGJE_01912 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPCKIGJE_01913 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPCKIGJE_01914 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPCKIGJE_01915 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPCKIGJE_01916 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPCKIGJE_01917 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HPCKIGJE_01918 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPCKIGJE_01919 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HPCKIGJE_01920 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPCKIGJE_01921 0.0 XK27_09800 I Acyltransferase
HPCKIGJE_01922 1.7e-35 XK27_09805 S MORN repeat protein
HPCKIGJE_01923 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPCKIGJE_01924 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPCKIGJE_01925 8.8e-83 adk 2.7.4.3 F topology modulation protein
HPCKIGJE_01926 3.1e-172 yxaM EGP Major facilitator Superfamily
HPCKIGJE_01927 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HPCKIGJE_01928 1.4e-53 L Transposase
HPCKIGJE_01929 2.8e-148 L Transposase
HPCKIGJE_01931 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HPCKIGJE_01932 0.0 KLT serine threonine protein kinase
HPCKIGJE_01933 2.1e-280 V ABC transporter
HPCKIGJE_01934 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HPCKIGJE_01935 7e-127 Z012_04635 K sequence-specific DNA binding
HPCKIGJE_01937 1.6e-53 C Radical SAM
HPCKIGJE_01938 1.3e-156 C Radical SAM
HPCKIGJE_01939 3.9e-287 V ABC transporter transmembrane region
HPCKIGJE_01940 1.3e-60 K sequence-specific DNA binding
HPCKIGJE_01941 3.1e-14 K Cro/C1-type HTH DNA-binding domain
HPCKIGJE_01942 2.2e-132 int L Belongs to the 'phage' integrase family
HPCKIGJE_01944 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HPCKIGJE_01945 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPCKIGJE_01946 2.8e-44 yrzL S Belongs to the UPF0297 family
HPCKIGJE_01947 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPCKIGJE_01948 4.2e-44 yrzB S Belongs to the UPF0473 family
HPCKIGJE_01949 1.4e-298 ccs S the current gene model (or a revised gene model) may contain a frame shift
HPCKIGJE_01950 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPCKIGJE_01951 7.5e-14
HPCKIGJE_01952 2.6e-91 XK27_10930 K acetyltransferase
HPCKIGJE_01953 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPCKIGJE_01954 1.8e-147 yaaA S Belongs to the UPF0246 family
HPCKIGJE_01955 9.3e-167 XK27_01785 S cog cog1284
HPCKIGJE_01956 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPCKIGJE_01958 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPCKIGJE_01959 2.5e-135 metE 2.1.1.14 E Methionine synthase
HPCKIGJE_01960 1.4e-36 metE 2.1.1.14 E Methionine synthase
HPCKIGJE_01961 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HPCKIGJE_01962 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPCKIGJE_01965 6e-44 yegS 2.7.1.107 I Diacylglycerol kinase
HPCKIGJE_01966 2.1e-81 yegS 2.7.1.107 I Diacylglycerol kinase
HPCKIGJE_01967 2.7e-95 S Hydrophobic domain protein
HPCKIGJE_01969 3.7e-27 S Membrane
HPCKIGJE_01970 5.9e-100
HPCKIGJE_01971 1.8e-23 S Small integral membrane protein
HPCKIGJE_01972 3.1e-85 M Protein conserved in bacteria
HPCKIGJE_01973 1.1e-11 K CsbD-like
HPCKIGJE_01974 3.4e-13 nudL L hydrolase
HPCKIGJE_01975 4e-19 K negative regulation of transcription, DNA-templated
HPCKIGJE_01976 1.7e-23 K negative regulation of transcription, DNA-templated
HPCKIGJE_01978 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
HPCKIGJE_01979 1.8e-88 S Putative adhesin
HPCKIGJE_01980 3.9e-161 XK27_06930 V domain protein
HPCKIGJE_01981 6.4e-96 XK27_06935 K transcriptional regulator
HPCKIGJE_01982 4.8e-55 ypaA M Membrane
HPCKIGJE_01983 2.7e-08
HPCKIGJE_01984 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPCKIGJE_01985 8.2e-48 veg S Biofilm formation stimulator VEG
HPCKIGJE_01986 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPCKIGJE_01987 3.9e-70 rplI J binds to the 23S rRNA
HPCKIGJE_01988 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPCKIGJE_01989 3.2e-228 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPCKIGJE_01990 1.5e-121 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPCKIGJE_01991 1.5e-77 F NUDIX domain
HPCKIGJE_01992 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPCKIGJE_01993 0.0 S Bacterial membrane protein, YfhO
HPCKIGJE_01994 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
HPCKIGJE_01995 5.3e-85 lytE M LysM domain protein
HPCKIGJE_01996 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPCKIGJE_01997 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPCKIGJE_01998 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPCKIGJE_01999 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPCKIGJE_02000 6.3e-138 ymfM S sequence-specific DNA binding
HPCKIGJE_02001 3.1e-242 ymfH S Peptidase M16
HPCKIGJE_02002 4.8e-235 ymfF S Peptidase M16
HPCKIGJE_02003 1.6e-45 yaaA S S4 domain protein YaaA
HPCKIGJE_02004 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPCKIGJE_02005 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HPCKIGJE_02006 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HPCKIGJE_02007 4.2e-153 yvjA S membrane
HPCKIGJE_02008 6.7e-306 ybiT S abc transporter atp-binding protein
HPCKIGJE_02009 0.0 XK27_10405 S Bacterial membrane protein YfhO
HPCKIGJE_02013 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HPCKIGJE_02014 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPCKIGJE_02015 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HPCKIGJE_02016 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)