ORF_ID e_value Gene_name EC_number CAZy COGs Description
PPPDDIND_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PPPDDIND_00002 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PPPDDIND_00003 2.7e-28 yyzM S Protein conserved in bacteria
PPPDDIND_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PPPDDIND_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PPPDDIND_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PPPDDIND_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PPPDDIND_00008 2.1e-61 divIC D Septum formation initiator
PPPDDIND_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PPPDDIND_00011 3.8e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PPPDDIND_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PPPDDIND_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PPPDDIND_00014 1.6e-134 L Transposase
PPPDDIND_00015 9.4e-46 L transposase activity
PPPDDIND_00016 2.5e-22 L Transposase
PPPDDIND_00017 1.2e-55 L transposition
PPPDDIND_00018 2e-88 L Integrase core domain protein
PPPDDIND_00031 5.3e-11
PPPDDIND_00037 8.6e-140 mreC M Involved in formation and maintenance of cell shape
PPPDDIND_00038 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PPPDDIND_00039 5.1e-87 usp 3.5.1.28 CBM50 S CHAP domain
PPPDDIND_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPPDDIND_00041 9.5e-26
PPPDDIND_00042 2.9e-218 araT 2.6.1.1 E Aminotransferase
PPPDDIND_00043 7e-144 recO L Involved in DNA repair and RecF pathway recombination
PPPDDIND_00044 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PPPDDIND_00045 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PPPDDIND_00046 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PPPDDIND_00047 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PPPDDIND_00048 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PPPDDIND_00049 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PPPDDIND_00050 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PPPDDIND_00051 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PPPDDIND_00052 1e-49 L transposase activity
PPPDDIND_00053 1.7e-51 L transposition
PPPDDIND_00054 1.2e-160 S CHAP domain
PPPDDIND_00055 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
PPPDDIND_00056 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PPPDDIND_00057 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PPPDDIND_00058 9.2e-141 1.1.1.169 H Ketopantoate reductase
PPPDDIND_00059 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PPPDDIND_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PPPDDIND_00061 8.2e-70 argR K Regulates arginine biosynthesis genes
PPPDDIND_00062 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PPPDDIND_00063 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PPPDDIND_00064 6.4e-35 S Protein of unknown function (DUF3021)
PPPDDIND_00065 1.2e-61 KT phosphorelay signal transduction system
PPPDDIND_00067 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PPPDDIND_00069 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PPPDDIND_00070 5.5e-28 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PPPDDIND_00071 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
PPPDDIND_00072 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PPPDDIND_00073 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PPPDDIND_00079 2.6e-10
PPPDDIND_00082 1.9e-07
PPPDDIND_00087 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPPDDIND_00088 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PPPDDIND_00089 5.5e-36 XK27_02060 S Transglycosylase associated protein
PPPDDIND_00090 2.6e-55 badR K DNA-binding transcription factor activity
PPPDDIND_00091 3.5e-97 S reductase
PPPDDIND_00092 1.1e-86 L Integrase core domain protein
PPPDDIND_00093 2.7e-39 L transposition
PPPDDIND_00095 2.1e-76 yocD 3.4.17.13 V carboxypeptidase activity
PPPDDIND_00096 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PPPDDIND_00098 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
PPPDDIND_00099 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PPPDDIND_00100 1.1e-83 S Putative small multi-drug export protein
PPPDDIND_00101 2.4e-75 ctsR K Belongs to the CtsR family
PPPDDIND_00102 0.0 clpC O Belongs to the ClpA ClpB family
PPPDDIND_00103 2.4e-101 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPDDIND_00104 8.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPDDIND_00105 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPDDIND_00106 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PPPDDIND_00107 2e-143 S SseB protein N-terminal domain
PPPDDIND_00108 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
PPPDDIND_00109 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPPDDIND_00110 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PPPDDIND_00113 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPPDDIND_00114 7e-92 yacP S RNA-binding protein containing a PIN domain
PPPDDIND_00115 3.4e-155 degV S DegV family
PPPDDIND_00116 1.8e-31 K helix-turn-helix
PPPDDIND_00117 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PPPDDIND_00118 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PPPDDIND_00119 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PPPDDIND_00120 9.1e-34 K Peptidase S24-like
PPPDDIND_00122 8.4e-102 S Lantibiotic dehydratase, C terminus
PPPDDIND_00123 0.0 S Lantibiotic dehydratase, C terminus
PPPDDIND_00124 2.4e-231 spaC2 V Lanthionine synthetase C family protein
PPPDDIND_00125 2.5e-183 EGP Major facilitator Superfamily
PPPDDIND_00126 1.6e-91 3.6.4.12 K Divergent AAA domain protein
PPPDDIND_00127 1.4e-50 int L Belongs to the 'phage' integrase family
PPPDDIND_00128 1.3e-27 int L Belongs to the 'phage' integrase family
PPPDDIND_00129 4.4e-13 S Helix-turn-helix domain
PPPDDIND_00131 1.1e-133
PPPDDIND_00132 6.2e-42
PPPDDIND_00133 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00134 6.8e-76 isp2 S pathogenesis
PPPDDIND_00135 5.7e-91 tnp L Transposase
PPPDDIND_00136 4.6e-42 capA M Bacterial capsule synthesis protein PGA_cap
PPPDDIND_00137 4.3e-109 capA M Bacterial capsule synthesis protein
PPPDDIND_00138 2.8e-57 capA M Bacterial capsule synthesis protein
PPPDDIND_00139 1e-38 gcvR T UPF0237 protein
PPPDDIND_00140 1.7e-243 XK27_08635 S UPF0210 protein
PPPDDIND_00141 3.2e-135 ais G Phosphoglycerate mutase
PPPDDIND_00142 8.8e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PPPDDIND_00143 5e-102 acmA 3.2.1.17 NU amidase activity
PPPDDIND_00144 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PPPDDIND_00145 1.5e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PPPDDIND_00146 7.5e-298 dnaK O Heat shock 70 kDa protein
PPPDDIND_00147 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PPPDDIND_00148 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PPPDDIND_00149 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PPPDDIND_00150 1.6e-61 hmpT S membrane
PPPDDIND_00163 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PPPDDIND_00164 2.5e-169 L Transposase
PPPDDIND_00165 9.9e-19 S Domain of unknown function (DUF4649)
PPPDDIND_00166 3.3e-55 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PPPDDIND_00167 4.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PPPDDIND_00168 3.2e-86
PPPDDIND_00169 1.6e-77 sigH K DNA-templated transcription, initiation
PPPDDIND_00170 1.6e-149 ykuT M mechanosensitive ion channel
PPPDDIND_00171 4.9e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PPPDDIND_00172 6.3e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PPPDDIND_00173 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PPPDDIND_00174 2.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
PPPDDIND_00175 1e-56 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PPPDDIND_00176 1.8e-178 prmA J Ribosomal protein L11 methyltransferase
PPPDDIND_00177 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PPPDDIND_00178 1.2e-29 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PPPDDIND_00179 4.7e-137 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PPPDDIND_00180 2.9e-183 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PPPDDIND_00181 1.8e-83 nrdI F Belongs to the NrdI family
PPPDDIND_00182 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PPPDDIND_00183 1e-72 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PPPDDIND_00184 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PPPDDIND_00185 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPDDIND_00186 4e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPDDIND_00187 1.6e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPDDIND_00188 2.5e-48 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPDDIND_00189 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PPPDDIND_00190 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPPDDIND_00191 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PPPDDIND_00192 9.3e-201 yhjX P Major Facilitator
PPPDDIND_00193 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PPPDDIND_00194 5e-94 V VanZ like family
PPPDDIND_00197 1.7e-123 glnQ E abc transporter atp-binding protein
PPPDDIND_00198 1.5e-275 glnP P ABC transporter
PPPDDIND_00199 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PPPDDIND_00200 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PPPDDIND_00201 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
PPPDDIND_00202 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PPPDDIND_00203 1.4e-234 sufD O assembly protein SufD
PPPDDIND_00204 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PPPDDIND_00205 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
PPPDDIND_00206 2.2e-273 sufB O assembly protein SufB
PPPDDIND_00207 2.4e-19 oppA E ABC transporter substrate-binding protein
PPPDDIND_00208 9.7e-138 oppA E ABC transporter substrate-binding protein
PPPDDIND_00209 1.9e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPDDIND_00210 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPDDIND_00211 2.7e-45 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPDDIND_00212 2e-59 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPDDIND_00213 3e-27 oppD P Belongs to the ABC transporter superfamily
PPPDDIND_00214 2.5e-32 oppD P Belongs to the ABC transporter superfamily
PPPDDIND_00215 3.3e-68 oppD P Belongs to the ABC transporter superfamily
PPPDDIND_00216 1.3e-44 oppD P Belongs to the ABC transporter superfamily
PPPDDIND_00217 8.7e-165 oppF P Belongs to the ABC transporter superfamily
PPPDDIND_00218 5.1e-11
PPPDDIND_00219 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PPPDDIND_00220 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PPPDDIND_00221 6e-128 K sequence-specific DNA binding
PPPDDIND_00222 0.0 KLT serine threonine protein kinase
PPPDDIND_00223 1.9e-223 EGP Major facilitator Superfamily
PPPDDIND_00224 3.1e-72 adcR K transcriptional
PPPDDIND_00225 6.4e-136 adcC P ABC transporter, ATP-binding protein
PPPDDIND_00226 2.8e-127 adcB P ABC transporter (Permease
PPPDDIND_00227 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PPPDDIND_00228 4.3e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
PPPDDIND_00229 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
PPPDDIND_00230 1.4e-154 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
PPPDDIND_00231 8.5e-108 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PPPDDIND_00232 2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PPPDDIND_00233 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
PPPDDIND_00234 1.9e-127 yeeN K transcriptional regulatory protein
PPPDDIND_00235 9.8e-50 yajC U protein transport
PPPDDIND_00236 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PPPDDIND_00237 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
PPPDDIND_00238 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PPPDDIND_00239 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PPPDDIND_00240 0.0 WQ51_06230 S ABC transporter substrate binding protein
PPPDDIND_00241 5.2e-142 cmpC S abc transporter atp-binding protein
PPPDDIND_00242 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PPPDDIND_00243 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PPPDDIND_00244 2.6e-77 L transposase activity
PPPDDIND_00245 1.7e-51 L transposition
PPPDDIND_00246 4.8e-34 L Integrase core domain protein
PPPDDIND_00249 4e-42
PPPDDIND_00250 2.7e-28 J TM2 domain
PPPDDIND_00251 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPPDDIND_00252 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPDDIND_00253 7.4e-25 secE U Belongs to the SecE SEC61-gamma family
PPPDDIND_00254 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PPPDDIND_00255 1.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PPPDDIND_00256 7e-56 cof Q phosphatase activity
PPPDDIND_00257 3.3e-36 cof Q phosphatase activity
PPPDDIND_00258 5.6e-138 glcR K transcriptional regulator (DeoR family)
PPPDDIND_00259 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPPDDIND_00260 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00261 1.7e-93 S thiolester hydrolase activity
PPPDDIND_00262 8.1e-145 S COG1073 Hydrolases of the alpha beta superfamily
PPPDDIND_00263 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PPPDDIND_00264 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PPPDDIND_00265 5.5e-77 yhaI L Membrane
PPPDDIND_00266 6e-260 pepC 3.4.22.40 E aminopeptidase
PPPDDIND_00267 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPDDIND_00268 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PPPDDIND_00269 3.1e-95 ypsA S Belongs to the UPF0398 family
PPPDDIND_00270 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PPPDDIND_00271 5.1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PPPDDIND_00272 0.0 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PPPDDIND_00273 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00274 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PPPDDIND_00275 2.5e-23
PPPDDIND_00276 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PPPDDIND_00277 4.6e-58 XK27_09675 K -acetyltransferase
PPPDDIND_00278 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PPPDDIND_00279 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PPPDDIND_00280 4.3e-83 L Integrase core domain protein
PPPDDIND_00281 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPPDDIND_00282 2.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PPPDDIND_00283 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPPDDIND_00284 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PPPDDIND_00285 8.8e-98 ybhL S Belongs to the BI1 family
PPPDDIND_00288 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PPPDDIND_00289 9.6e-92 K transcriptional regulator
PPPDDIND_00290 7.6e-36 yneF S UPF0154 protein
PPPDDIND_00291 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PPPDDIND_00292 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PPPDDIND_00293 3.5e-99 XK27_09740 S Phosphoesterase
PPPDDIND_00294 5.4e-86 ykuL S CBS domain
PPPDDIND_00295 7.5e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PPPDDIND_00296 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PPPDDIND_00297 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PPPDDIND_00298 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPDDIND_00299 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PPPDDIND_00300 1.2e-258 trkH P Cation transport protein
PPPDDIND_00301 1.8e-248 trkA P Potassium transporter peripheral membrane component
PPPDDIND_00302 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PPPDDIND_00303 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PPPDDIND_00304 7e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PPPDDIND_00305 2.5e-161 K sequence-specific DNA binding
PPPDDIND_00306 1.9e-33 V protein secretion by the type I secretion system
PPPDDIND_00307 1.6e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPDDIND_00308 6.9e-34 V protein secretion by the type I secretion system
PPPDDIND_00309 4.3e-63 comA V protein secretion by the type I secretion system
PPPDDIND_00310 1.4e-69 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPDDIND_00311 1.6e-43 yhaI L Membrane
PPPDDIND_00312 2.6e-35 S Domain of unknown function (DUF4173)
PPPDDIND_00313 1.6e-53 S Domain of unknown function (DUF4173)
PPPDDIND_00314 7.5e-94 ureI S AmiS/UreI family transporter
PPPDDIND_00315 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PPPDDIND_00316 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PPPDDIND_00317 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PPPDDIND_00318 6.6e-78 ureE O enzyme active site formation
PPPDDIND_00319 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PPPDDIND_00320 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PPPDDIND_00321 5.8e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PPPDDIND_00322 3.5e-177 cbiM P PDGLE domain
PPPDDIND_00323 2.9e-137 P cobalt transport protein
PPPDDIND_00324 1.6e-131 cbiO P ABC transporter
PPPDDIND_00325 3.4e-152 ET amino acid transport
PPPDDIND_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPDDIND_00327 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
PPPDDIND_00328 3.8e-205 EGP Transmembrane secretion effector
PPPDDIND_00329 1.8e-153 ET amino acid transport
PPPDDIND_00330 5.1e-159 metQ M Belongs to the NlpA lipoprotein family
PPPDDIND_00331 1.3e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PPPDDIND_00332 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PPPDDIND_00333 1.7e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PPPDDIND_00334 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PPPDDIND_00335 3e-98 metI P ABC transporter (Permease
PPPDDIND_00336 1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PPPDDIND_00337 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PPPDDIND_00338 8e-94 S UPF0397 protein
PPPDDIND_00339 0.0 ykoD P abc transporter atp-binding protein
PPPDDIND_00340 1.7e-148 cbiQ P cobalt transport
PPPDDIND_00341 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PPPDDIND_00342 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
PPPDDIND_00343 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
PPPDDIND_00344 4.2e-245 P COG0168 Trk-type K transport systems, membrane components
PPPDDIND_00345 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PPPDDIND_00346 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
PPPDDIND_00347 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPDDIND_00348 1.4e-281 T PhoQ Sensor
PPPDDIND_00349 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PPPDDIND_00350 1.3e-218 dnaB L Replication initiation and membrane attachment
PPPDDIND_00351 4e-167 dnaI L Primosomal protein DnaI
PPPDDIND_00352 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PPPDDIND_00353 3.5e-283 P ABC transporter transmembrane region
PPPDDIND_00355 7.5e-50 L Transposase
PPPDDIND_00356 1.1e-147 L Transposase
PPPDDIND_00357 9.8e-25 S Protein of unknown function DUF262
PPPDDIND_00358 4.6e-233 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PPPDDIND_00359 5e-63 manO S protein conserved in bacteria
PPPDDIND_00360 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
PPPDDIND_00361 9e-65 manM G pts system
PPPDDIND_00362 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PPPDDIND_00363 9.8e-183 manL 2.7.1.191 G pts system
PPPDDIND_00364 7.4e-36 manM G pts system
PPPDDIND_00365 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PPPDDIND_00366 1.5e-248 pbuO S permease
PPPDDIND_00367 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PPPDDIND_00368 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
PPPDDIND_00369 2.5e-220 brpA K Transcriptional
PPPDDIND_00370 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
PPPDDIND_00371 4.1e-212 nusA K Participates in both transcription termination and antitermination
PPPDDIND_00372 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PPPDDIND_00373 1.4e-41 ylxQ J ribosomal protein
PPPDDIND_00374 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PPPDDIND_00375 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PPPDDIND_00376 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
PPPDDIND_00377 4e-38 yvdD 3.2.2.10 L Belongs to the LOG family
PPPDDIND_00378 1.4e-234 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PPPDDIND_00379 1.1e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PPPDDIND_00380 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PPPDDIND_00381 1e-87 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PPPDDIND_00382 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
PPPDDIND_00383 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PPPDDIND_00385 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PPPDDIND_00386 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PPPDDIND_00387 1.2e-74 ylbF S Belongs to the UPF0342 family
PPPDDIND_00388 7.1e-46 ylbG S UPF0298 protein
PPPDDIND_00389 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PPPDDIND_00390 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
PPPDDIND_00391 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
PPPDDIND_00392 8.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PPPDDIND_00393 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PPPDDIND_00394 9.5e-71 acuB S IMP dehydrogenase activity
PPPDDIND_00395 3.3e-43 acuB S IMP dehydrogenase activity
PPPDDIND_00396 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPPDDIND_00397 1.4e-110 yvyE 3.4.13.9 S YigZ family
PPPDDIND_00398 8.2e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PPPDDIND_00399 3.4e-123 comFC S Competence protein
PPPDDIND_00400 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PPPDDIND_00401 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00409 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
PPPDDIND_00410 6.4e-108 S Domain of unknown function (DUF1803)
PPPDDIND_00411 7.8e-102 ygaC J Belongs to the UPF0374 family
PPPDDIND_00412 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
PPPDDIND_00413 5.2e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPPDDIND_00414 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
PPPDDIND_00415 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
PPPDDIND_00416 1.9e-115 S Haloacid dehalogenase-like hydrolase
PPPDDIND_00417 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PPPDDIND_00418 8.9e-72 marR K Transcriptional regulator, MarR family
PPPDDIND_00419 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PPPDDIND_00420 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PPPDDIND_00421 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PPPDDIND_00422 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PPPDDIND_00423 1.3e-126 IQ reductase
PPPDDIND_00424 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PPPDDIND_00425 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PPPDDIND_00426 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PPPDDIND_00427 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PPPDDIND_00428 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PPPDDIND_00429 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PPPDDIND_00430 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PPPDDIND_00431 1.8e-127 tnp L Transposase
PPPDDIND_00432 9.2e-207 rny D Endoribonuclease that initiates mRNA decay
PPPDDIND_00433 4.7e-85 L Transposase
PPPDDIND_00434 5.6e-114 fruR K transcriptional
PPPDDIND_00435 6.5e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PPPDDIND_00436 9.6e-53 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
PPPDDIND_00437 1.7e-21 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
PPPDDIND_00438 1.4e-25 fruA 2.7.1.202 G phosphotransferase system
PPPDDIND_00439 2.2e-104 fruA 2.7.1.202 G phosphotransferase system
PPPDDIND_00440 1.5e-47 fruA 2.7.1.202 G phosphotransferase system
PPPDDIND_00441 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPPDDIND_00442 2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PPPDDIND_00444 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PPPDDIND_00445 7.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PPPDDIND_00446 8.4e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PPPDDIND_00447 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PPPDDIND_00448 1.1e-38 2.3.1.128 K acetyltransferase
PPPDDIND_00449 6.4e-29 2.3.1.128 K acetyltransferase
PPPDDIND_00450 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PPPDDIND_00451 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PPPDDIND_00452 2.1e-99 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPPDDIND_00453 1.3e-37 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPPDDIND_00454 2.6e-64 WQ51_03320 S cog cog4835
PPPDDIND_00455 2.9e-31 XK27_08360 S lipid binding
PPPDDIND_00456 3.4e-109 XK27_08360 T EDD domain protein, DegV family
PPPDDIND_00457 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PPPDDIND_00458 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PPPDDIND_00459 0.0 yfmR S abc transporter atp-binding protein
PPPDDIND_00460 1.6e-24 U response to pH
PPPDDIND_00461 1.4e-136 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PPPDDIND_00462 2.2e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PPPDDIND_00463 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPPDDIND_00464 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PPPDDIND_00466 1.9e-77 K DNA-binding transcription factor activity
PPPDDIND_00467 0.0 lmrA1 V abc transporter atp-binding protein
PPPDDIND_00468 0.0 lmrA2 V abc transporter atp-binding protein
PPPDDIND_00469 2.3e-122 sptS 2.7.13.3 T Histidine kinase
PPPDDIND_00470 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PPPDDIND_00471 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PPPDDIND_00472 5.3e-161 cvfB S Protein conserved in bacteria
PPPDDIND_00473 7.4e-35 yozE S Belongs to the UPF0346 family
PPPDDIND_00474 9.4e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
PPPDDIND_00475 1.9e-13
PPPDDIND_00476 9e-184 L Transposase
PPPDDIND_00477 1.4e-61 rlpA M LysM domain protein
PPPDDIND_00478 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
PPPDDIND_00482 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PPPDDIND_00483 3.4e-166 K transcriptional regulator (lysR family)
PPPDDIND_00484 1.4e-186 coiA 3.6.4.12 S Competence protein
PPPDDIND_00485 0.0 pepF E oligoendopeptidase F
PPPDDIND_00486 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
PPPDDIND_00487 1.2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PPPDDIND_00488 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PPPDDIND_00489 4.6e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPDDIND_00490 1.7e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPDDIND_00491 5.8e-42 S pathogenesis
PPPDDIND_00492 5e-123 3.4.17.14, 3.5.1.28 NU amidase activity
PPPDDIND_00493 5.3e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PPPDDIND_00494 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PPPDDIND_00495 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PPPDDIND_00496 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PPPDDIND_00497 1.8e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PPPDDIND_00498 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PPPDDIND_00499 5.5e-141 yxkH G deacetylase
PPPDDIND_00500 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PPPDDIND_00501 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PPPDDIND_00502 7.2e-153 rarD S Transporter
PPPDDIND_00503 2.2e-15 T peptidase
PPPDDIND_00504 8.9e-14 coiA 3.6.4.12 S Competence protein
PPPDDIND_00505 1.7e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PPPDDIND_00506 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPPDDIND_00507 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PPPDDIND_00508 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPPDDIND_00509 9e-114 atpB C it plays a direct role in the translocation of protons across the membrane
PPPDDIND_00510 3.3e-78 atpF C ATP synthase F(0) sector subunit b
PPPDDIND_00511 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPPDDIND_00512 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PPPDDIND_00513 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PPPDDIND_00514 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PPPDDIND_00515 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PPPDDIND_00516 8.1e-230 ftsW D Belongs to the SEDS family
PPPDDIND_00517 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PPPDDIND_00518 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PPPDDIND_00519 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PPPDDIND_00520 6.4e-162 holB 2.7.7.7 L dna polymerase iii
PPPDDIND_00521 1.2e-135 yaaT S stage 0 sporulation protein
PPPDDIND_00522 9.5e-55 yabA L Involved in initiation control of chromosome replication
PPPDDIND_00523 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PPPDDIND_00524 1.7e-232 amt P Ammonium Transporter
PPPDDIND_00525 6.6e-54 glnB K Belongs to the P(II) protein family
PPPDDIND_00526 2.7e-104 mur1 NU mannosyl-glycoprotein
PPPDDIND_00527 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PPPDDIND_00528 1.3e-32 nptA P sodium-dependent phosphate transmembrane transporter activity
PPPDDIND_00529 3.2e-85 nptA P COG1283 Na phosphate symporter
PPPDDIND_00530 2.3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PPPDDIND_00531 7.4e-55
PPPDDIND_00532 2.8e-25
PPPDDIND_00533 7.8e-61
PPPDDIND_00534 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PPPDDIND_00535 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PPPDDIND_00536 4.5e-39 ynzC S UPF0291 protein
PPPDDIND_00537 2.5e-253 cycA E permease
PPPDDIND_00538 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
PPPDDIND_00539 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PPPDDIND_00540 5.8e-71 pts33BCA G pts system
PPPDDIND_00541 9e-96 pts33BCA G pts system
PPPDDIND_00542 2e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
PPPDDIND_00543 6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPPDDIND_00548 1.2e-166 fhuR K transcriptional regulator (lysR family)
PPPDDIND_00549 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PPPDDIND_00550 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPPDDIND_00551 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PPPDDIND_00552 3.7e-227 pyrP F uracil Permease
PPPDDIND_00553 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PPPDDIND_00554 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PPPDDIND_00555 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PPPDDIND_00556 1.7e-134 J Putative SAM-dependent methyltransferase
PPPDDIND_00557 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPDDIND_00558 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPDDIND_00559 3.8e-43 V permease protein
PPPDDIND_00560 8.3e-35 V permease protein
PPPDDIND_00561 3.7e-22 V efflux transmembrane transporter activity
PPPDDIND_00562 7e-27 ytrF V efflux transmembrane transporter activity
PPPDDIND_00563 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PPPDDIND_00564 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PPPDDIND_00566 0.0 mdlB V abc transporter atp-binding protein
PPPDDIND_00567 0.0 lmrA V abc transporter atp-binding protein
PPPDDIND_00568 1.8e-195 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PPPDDIND_00569 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PPPDDIND_00570 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PPPDDIND_00571 1.9e-132 rr02 KT response regulator
PPPDDIND_00572 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PPPDDIND_00573 1.8e-167 V ABC transporter
PPPDDIND_00574 5.4e-122 sagI S ABC-2 type transporter
PPPDDIND_00575 6.9e-197 yceA S Belongs to the UPF0176 family
PPPDDIND_00576 1.9e-29 XK27_00085 K Transcriptional
PPPDDIND_00577 4.3e-22
PPPDDIND_00578 2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
PPPDDIND_00579 2.5e-113 S VIT family
PPPDDIND_00580 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPDDIND_00581 6.8e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PPPDDIND_00582 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
PPPDDIND_00583 2e-43 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PPPDDIND_00585 3.6e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPPDDIND_00586 4.6e-105 GBS0088 J protein conserved in bacteria
PPPDDIND_00587 9.6e-150 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PPPDDIND_00588 2.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PPPDDIND_00589 4.3e-178 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
PPPDDIND_00590 5.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PPPDDIND_00591 5.6e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PPPDDIND_00592 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PPPDDIND_00593 2.5e-21
PPPDDIND_00594 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PPPDDIND_00596 3.5e-07 U protein secretion
PPPDDIND_00597 5.5e-51 U protein secretion
PPPDDIND_00598 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PPPDDIND_00599 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PPPDDIND_00600 6.4e-21 XK27_13030
PPPDDIND_00601 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PPPDDIND_00602 1.1e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PPPDDIND_00603 7.3e-166 S Protein of unknown function (DUF3114)
PPPDDIND_00604 3.6e-22 S Protein of unknown function (DUF3114)
PPPDDIND_00605 3.6e-120 yqfA K protein, Hemolysin III
PPPDDIND_00606 1.6e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PPPDDIND_00607 1.7e-218 mvaS 2.3.3.10 I synthase
PPPDDIND_00608 2.9e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PPPDDIND_00609 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PPPDDIND_00610 9.7e-22
PPPDDIND_00611 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PPPDDIND_00612 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PPPDDIND_00613 3.7e-249 mmuP E amino acid
PPPDDIND_00614 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PPPDDIND_00615 1.4e-29 S Domain of unknown function (DUF1912)
PPPDDIND_00616 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
PPPDDIND_00617 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PPPDDIND_00618 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPPDDIND_00619 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPPDDIND_00620 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
PPPDDIND_00621 4.8e-16 S Protein of unknown function (DUF2969)
PPPDDIND_00624 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
PPPDDIND_00627 5.1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
PPPDDIND_00628 3.9e-31 S Domain of Unknown Function with PDB structure (DUF3862)
PPPDDIND_00629 8.2e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
PPPDDIND_00630 7.8e-08 S oxidoreductase
PPPDDIND_00631 7e-26 2.7.7.15 S inositol 2-dehydrogenase activity
PPPDDIND_00632 1.4e-50 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
PPPDDIND_00633 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
PPPDDIND_00634 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PPPDDIND_00635 0.0 clpE O Belongs to the ClpA ClpB family
PPPDDIND_00636 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PPPDDIND_00637 1.3e-34 ykuJ S protein conserved in bacteria
PPPDDIND_00638 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PPPDDIND_00639 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_00640 4.1e-78 feoA P FeoA domain protein
PPPDDIND_00641 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PPPDDIND_00642 6.6e-08
PPPDDIND_00643 1.5e-35 yugF I carboxylic ester hydrolase activity
PPPDDIND_00644 7.5e-23 I Alpha/beta hydrolase family
PPPDDIND_00645 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PPPDDIND_00646 2e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PPPDDIND_00647 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PPPDDIND_00648 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PPPDDIND_00649 5.8e-64 licT K transcriptional antiterminator
PPPDDIND_00650 3.4e-52 licT K transcriptional antiterminator
PPPDDIND_00651 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PPPDDIND_00652 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PPPDDIND_00653 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PPPDDIND_00654 5.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PPPDDIND_00655 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PPPDDIND_00656 2.9e-221 mdtG EGP Major facilitator Superfamily
PPPDDIND_00657 2e-33 secG U Preprotein translocase subunit SecG
PPPDDIND_00658 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PPPDDIND_00659 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PPPDDIND_00660 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPPDDIND_00661 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PPPDDIND_00662 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PPPDDIND_00663 4.4e-183 ccpA K Catabolite control protein A
PPPDDIND_00664 4e-27 yyaQ S YjbR
PPPDDIND_00665 7.4e-146 yyaQ S YjbR
PPPDDIND_00666 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PPPDDIND_00667 1.3e-78 yueI S Protein of unknown function (DUF1694)
PPPDDIND_00668 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PPPDDIND_00669 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPPDDIND_00670 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
PPPDDIND_00671 2.9e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PPPDDIND_00672 3.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PPPDDIND_00673 4.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PPPDDIND_00674 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PPPDDIND_00675 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PPPDDIND_00676 3.2e-53 yheA S Belongs to the UPF0342 family
PPPDDIND_00677 5.7e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PPPDDIND_00678 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PPPDDIND_00679 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PPPDDIND_00680 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
PPPDDIND_00681 1.1e-59 msrR K Transcriptional regulator
PPPDDIND_00682 7.7e-177 msrR K Transcriptional regulator
PPPDDIND_00683 2.9e-160 ydiA P C4-dicarboxylate transporter malic acid transport
PPPDDIND_00684 4.5e-202 I acyl-CoA dehydrogenase
PPPDDIND_00685 7.7e-97 mip S hydroperoxide reductase activity
PPPDDIND_00686 5.9e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPPDDIND_00687 1.6e-84
PPPDDIND_00688 1e-31 K Cro/C1-type HTH DNA-binding domain
PPPDDIND_00689 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
PPPDDIND_00690 2.4e-28 estA E GDSL-like Lipase/Acylhydrolase
PPPDDIND_00691 1.8e-94
PPPDDIND_00692 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PPPDDIND_00693 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00694 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPDDIND_00695 2.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPDDIND_00696 1.9e-189 S CRISPR-associated protein Csn2 subfamily St
PPPDDIND_00697 3.4e-149 ycgQ S TIGR03943 family
PPPDDIND_00698 3.4e-158 XK27_03015 S permease
PPPDDIND_00700 0.0 yhgF K Transcriptional accessory protein
PPPDDIND_00701 4.9e-86 ydcK S Belongs to the SprT family
PPPDDIND_00702 2.9e-41 pspC KT PspC domain
PPPDDIND_00703 3.1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PPPDDIND_00704 1.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PPPDDIND_00706 1e-67 ytxH S General stress protein
PPPDDIND_00708 3e-178 yegQ O Peptidase U32
PPPDDIND_00709 3.4e-252 yegQ O Peptidase U32
PPPDDIND_00710 1e-88 bioY S biotin synthase
PPPDDIND_00712 1.1e-33 XK27_12190 S protein conserved in bacteria
PPPDDIND_00713 2.7e-236 mntH P H( )-stimulated, divalent metal cation uptake system
PPPDDIND_00714 2.4e-10
PPPDDIND_00715 7e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
PPPDDIND_00716 1.5e-100 L helicase
PPPDDIND_00717 2.1e-39
PPPDDIND_00718 6.3e-38
PPPDDIND_00722 7.8e-19 pvuIIC K Helix-turn-helix domain
PPPDDIND_00723 1.3e-25
PPPDDIND_00724 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00725 2.2e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PPPDDIND_00726 3.4e-22 M LysM domain
PPPDDIND_00727 3.5e-52 M LysM domain
PPPDDIND_00728 2.1e-42 M LysM domain
PPPDDIND_00729 5.9e-16
PPPDDIND_00730 2.3e-175 S hydrolase
PPPDDIND_00731 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PPPDDIND_00732 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PPPDDIND_00733 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PPPDDIND_00734 2.7e-27 P Hemerythrin HHE cation binding domain protein
PPPDDIND_00735 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPPDDIND_00736 2.3e-10 MA20_36090 S Protein of unknown function (DUF2974)
PPPDDIND_00737 2.7e-37 MA20_36090 S Protein of unknown function (DUF2974)
PPPDDIND_00738 1.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPDDIND_00739 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPDDIND_00740 1.2e-307 S AAA domain, putative AbiEii toxin, Type IV TA system
PPPDDIND_00742 5.1e-226 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
PPPDDIND_00743 0.0 S KAP family P-loop domain
PPPDDIND_00744 6.1e-137 S Protein conserved in bacteria
PPPDDIND_00745 5.1e-306 hsdM 2.1.1.72 V type I restriction-modification system
PPPDDIND_00746 3e-12 S double-stranded DNA endodeoxyribonuclease activity
PPPDDIND_00747 4.5e-26 S PD-(D/E)XK nuclease family transposase
PPPDDIND_00748 2.8e-177 spd F DNA RNA non-specific endonuclease
PPPDDIND_00749 1.5e-92 lemA S LemA family
PPPDDIND_00750 2.1e-144 htpX O Belongs to the peptidase M48B family
PPPDDIND_00751 3.6e-74 S Psort location CytoplasmicMembrane, score
PPPDDIND_00752 1.1e-55 S Domain of unknown function (DUF4430)
PPPDDIND_00753 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PPPDDIND_00754 7.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PPPDDIND_00755 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PPPDDIND_00756 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PPPDDIND_00757 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PPPDDIND_00758 1.6e-91 dps P Belongs to the Dps family
PPPDDIND_00759 1.1e-80 perR P Belongs to the Fur family
PPPDDIND_00760 8.4e-28 yqgQ S protein conserved in bacteria
PPPDDIND_00761 2.2e-179 glk 2.7.1.2 G Glucokinase
PPPDDIND_00762 0.0 typA T GTP-binding protein TypA
PPPDDIND_00764 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PPPDDIND_00765 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PPPDDIND_00766 2.2e-178 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PPPDDIND_00767 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PPPDDIND_00768 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PPPDDIND_00769 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PPPDDIND_00770 2.3e-96 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PPPDDIND_00771 8.8e-35 yggT D integral membrane protein
PPPDDIND_00772 4.7e-143 ylmH T S4 RNA-binding domain
PPPDDIND_00773 7.9e-136 divIVA D Cell division protein DivIVA
PPPDDIND_00774 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PPPDDIND_00775 1.2e-17
PPPDDIND_00776 8.4e-10
PPPDDIND_00777 1e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
PPPDDIND_00778 2e-45 rpmE2 J 50S ribosomal protein L31
PPPDDIND_00779 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PPPDDIND_00780 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PPPDDIND_00781 2e-154 gst O Glutathione S-transferase
PPPDDIND_00782 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PPPDDIND_00783 4.5e-111 tdk 2.7.1.21 F thymidine kinase
PPPDDIND_00784 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PPPDDIND_00785 4e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PPPDDIND_00786 1.1e-107 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PPPDDIND_00787 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PPPDDIND_00788 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
PPPDDIND_00789 2.4e-107 pvaA M lytic transglycosylase activity
PPPDDIND_00790 0.0 yfiB1 V abc transporter atp-binding protein
PPPDDIND_00791 0.0 XK27_10035 V abc transporter atp-binding protein
PPPDDIND_00792 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
PPPDDIND_00793 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPDDIND_00794 4.6e-238 dltB M Membrane protein involved in D-alanine export
PPPDDIND_00795 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPDDIND_00796 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PPPDDIND_00797 2.7e-52 L transposition
PPPDDIND_00798 3.4e-19 L transposase activity
PPPDDIND_00799 0.0 3.6.3.8 P cation transport ATPase
PPPDDIND_00800 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PPPDDIND_00802 6.6e-12
PPPDDIND_00804 1.6e-282 S DNA primase
PPPDDIND_00805 1.2e-141 KL Phage plasmid primase P4 family
PPPDDIND_00806 3.1e-22
PPPDDIND_00807 1.2e-14
PPPDDIND_00811 1.7e-17 K Cro/C1-type HTH DNA-binding domain
PPPDDIND_00813 6.9e-220 sip L Belongs to the 'phage' integrase family
PPPDDIND_00815 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PPPDDIND_00816 7.3e-166 metF 1.5.1.20 C reductase
PPPDDIND_00817 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PPPDDIND_00818 1.4e-93 panT S ECF transporter, substrate-specific component
PPPDDIND_00819 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PPPDDIND_00820 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PPPDDIND_00821 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PPPDDIND_00822 1.1e-84 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPDDIND_00823 4.3e-41 T PhoQ Sensor
PPPDDIND_00824 1.7e-43 T PhoQ Sensor
PPPDDIND_00825 1.9e-127 T PhoQ Sensor
PPPDDIND_00826 1.2e-165 L integrase core domain
PPPDDIND_00827 3.9e-122 L Transposase
PPPDDIND_00828 2.1e-30 rpsT J rRNA binding
PPPDDIND_00829 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
PPPDDIND_00830 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
PPPDDIND_00831 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
PPPDDIND_00832 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
PPPDDIND_00833 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PPPDDIND_00834 8.6e-65 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
PPPDDIND_00835 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PPPDDIND_00836 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PPPDDIND_00837 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PPPDDIND_00838 7.3e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PPPDDIND_00839 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PPPDDIND_00840 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
PPPDDIND_00841 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
PPPDDIND_00842 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PPPDDIND_00843 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PPPDDIND_00844 6.8e-81 ypmB S Protein conserved in bacteria
PPPDDIND_00845 1.9e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PPPDDIND_00846 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PPPDDIND_00848 8.1e-08
PPPDDIND_00849 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PPPDDIND_00850 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PPPDDIND_00851 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
PPPDDIND_00852 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PPPDDIND_00853 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PPPDDIND_00854 7.7e-20 D nuclear chromosome segregation
PPPDDIND_00855 7.4e-138 yejC S cyclic nucleotide-binding protein
PPPDDIND_00856 1.2e-163 rapZ S Displays ATPase and GTPase activities
PPPDDIND_00857 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PPPDDIND_00858 8.7e-162 whiA K May be required for sporulation
PPPDDIND_00859 2.8e-90 pepD E Dipeptidase
PPPDDIND_00860 5.4e-32 cspD K Cold shock protein domain
PPPDDIND_00861 9.4e-43 K Cold-Shock Protein
PPPDDIND_00862 3.6e-224 L Transposase, Mutator family
PPPDDIND_00863 0.0 copB 3.6.3.4 P P-type ATPase
PPPDDIND_00864 5.3e-220 L Transposase
PPPDDIND_00865 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPDDIND_00866 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPPDDIND_00867 2e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PPPDDIND_00868 5.2e-62 cysE 2.3.1.30 E serine acetyltransferase
PPPDDIND_00869 2.6e-222 L Transposase
PPPDDIND_00870 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
PPPDDIND_00871 1.7e-63 hsdM 2.1.1.72 V type I restriction-modification system
PPPDDIND_00872 1.5e-33 hsdM 2.1.1.72 V type I restriction-modification system
PPPDDIND_00873 2.2e-157 glcU U Glucose uptake
PPPDDIND_00874 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
PPPDDIND_00875 2.9e-78 hsdM 2.1.1.72 V HsdM N-terminal domain
PPPDDIND_00876 2.5e-110 XK27_10720 D peptidase activity
PPPDDIND_00877 2.3e-295 adcA P Belongs to the bacterial solute-binding protein 9 family
PPPDDIND_00878 1.7e-08
PPPDDIND_00880 1.4e-109 L Transposase
PPPDDIND_00881 2.5e-46
PPPDDIND_00882 7.1e-17
PPPDDIND_00883 1e-171 yeiH S Membrane
PPPDDIND_00884 7.1e-114 mur1 NU muramidase
PPPDDIND_00885 1.3e-97 L transposition
PPPDDIND_00886 2.6e-166 cpsY K Transcriptional regulator
PPPDDIND_00887 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PPPDDIND_00888 5.6e-58 phnA P Alkylphosphonate utilization operon protein PhnA
PPPDDIND_00889 2.4e-105 artQ P ABC transporter (Permease
PPPDDIND_00890 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_00891 8.4e-159 aatB ET ABC transporter substrate-binding protein
PPPDDIND_00892 5.8e-149 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPDDIND_00893 2.1e-07
PPPDDIND_00894 7.8e-25
PPPDDIND_00895 4.6e-63 adhP 1.1.1.1 C alcohol dehydrogenase
PPPDDIND_00896 1.8e-15 adhP 1.1.1.1 P alcohol dehydrogenase
PPPDDIND_00897 2.4e-81 adhP 1.1.1.1 C alcohol dehydrogenase
PPPDDIND_00898 2.7e-22
PPPDDIND_00899 0.0 res_1 3.1.21.5 S Type III restriction
PPPDDIND_00900 6.2e-279 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PPPDDIND_00901 6.5e-93 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PPPDDIND_00902 1.8e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PPPDDIND_00903 1.6e-126 gntR1 K transcriptional
PPPDDIND_00904 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PPPDDIND_00905 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PPPDDIND_00906 3.1e-87 niaX
PPPDDIND_00907 6e-91 niaR S small molecule binding protein (contains 3H domain)
PPPDDIND_00908 5.6e-129 K DNA-binding helix-turn-helix protein
PPPDDIND_00909 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PPPDDIND_00910 2.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPPDDIND_00911 3.7e-168 GK ROK family
PPPDDIND_00912 2.4e-158 dprA LU DNA protecting protein DprA
PPPDDIND_00913 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PPPDDIND_00914 6.7e-153 S TraX protein
PPPDDIND_00915 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPDDIND_00916 2.8e-252 T PhoQ Sensor
PPPDDIND_00917 2.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PPPDDIND_00918 2e-154 XK27_05470 E Methionine synthase
PPPDDIND_00919 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PPPDDIND_00920 7.3e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PPPDDIND_00921 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
PPPDDIND_00922 6.6e-54 IQ Acetoin reductase
PPPDDIND_00923 3.9e-19 IQ Acetoin reductase
PPPDDIND_00924 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PPPDDIND_00928 1.1e-53 K peptidyl-tyrosine sulfation
PPPDDIND_00929 2.6e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPDDIND_00932 1.3e-212 pqqE C radical SAM domain protein
PPPDDIND_00933 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
PPPDDIND_00934 6.6e-61 EGP Major facilitator Superfamily
PPPDDIND_00935 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PPPDDIND_00936 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PPPDDIND_00937 1.9e-13
PPPDDIND_00938 5.1e-176 L Transposase
PPPDDIND_00939 4.6e-13 L Transposase
PPPDDIND_00940 5.9e-116 V ABC transporter (Permease
PPPDDIND_00941 3.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPDDIND_00942 1.6e-10
PPPDDIND_00943 6.9e-98 K Transcriptional regulator, TetR family
PPPDDIND_00944 2.3e-159 czcD P cation diffusion facilitator family transporter
PPPDDIND_00945 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PPPDDIND_00946 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PPPDDIND_00947 8.1e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PPPDDIND_00948 6e-08 S Hydrolases of the alpha beta superfamily
PPPDDIND_00949 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
PPPDDIND_00950 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
PPPDDIND_00953 6.9e-144 2.4.2.3 F Phosphorylase superfamily
PPPDDIND_00954 9.8e-120 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PPPDDIND_00955 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
PPPDDIND_00956 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
PPPDDIND_00957 4.2e-75 dinF V Mate efflux family protein
PPPDDIND_00959 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PPPDDIND_00961 9.7e-89 S TraX protein
PPPDDIND_00962 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PPPDDIND_00963 1.2e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PPPDDIND_00964 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PPPDDIND_00965 2.8e-111 cas1 L maintenance of DNA repeat elements
PPPDDIND_00966 2.2e-69 cas1 L maintenance of DNA repeat elements
PPPDDIND_00967 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPDDIND_00968 6.8e-133 cas6 S Pfam:DUF2276
PPPDDIND_00969 0.0 csm1 S CRISPR-associated protein Csm1 family
PPPDDIND_00970 5.6e-62 csm2 L Pfam:DUF310
PPPDDIND_00971 1.6e-117 csm3 L RAMP superfamily
PPPDDIND_00972 1.3e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
PPPDDIND_00973 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
PPPDDIND_00974 6.5e-89 csm6 S Psort location Cytoplasmic, score
PPPDDIND_00975 3.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PPPDDIND_00976 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PPPDDIND_00978 9.3e-55 nylA 3.5.1.4 J Belongs to the amidase family
PPPDDIND_00979 6.5e-268 dtpT E transporter
PPPDDIND_00980 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_00981 2.2e-106 nylA 3.5.1.4 J Belongs to the amidase family
PPPDDIND_00982 4.6e-73 yckB ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_00983 3.2e-59 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_00984 3.3e-68 yecS P ABC transporter (Permease
PPPDDIND_00985 9.2e-22 yecS P amino acid transport
PPPDDIND_00987 5.2e-273 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PPPDDIND_00988 1.9e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
PPPDDIND_00989 5.9e-103 yfiF3 K sequence-specific DNA binding
PPPDDIND_00990 1e-22 bglC K Transcriptional regulator
PPPDDIND_00991 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PPPDDIND_00992 4e-240 agcS E (Alanine) symporter
PPPDDIND_00993 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PPPDDIND_00994 3.9e-187 metY 2.5.1.49 E o-acetylhomoserine
PPPDDIND_00995 1.7e-45 metY 2.5.1.49 E o-acetylhomoserine
PPPDDIND_00996 1.8e-59 Q phosphatase activity
PPPDDIND_00997 9.3e-62 S haloacid dehalogenase-like hydrolase
PPPDDIND_00998 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PPPDDIND_00999 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PPPDDIND_01000 9e-213 XK27_04775 S hemerythrin HHE cation binding domain
PPPDDIND_01001 4.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PPPDDIND_01002 1.7e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PPPDDIND_01003 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PPPDDIND_01004 2.3e-44 yktA S Belongs to the UPF0223 family
PPPDDIND_01005 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PPPDDIND_01006 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PPPDDIND_01007 5.6e-158 pstS P phosphate
PPPDDIND_01008 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PPPDDIND_01009 1.2e-155 pstA P phosphate transport system permease
PPPDDIND_01010 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPPDDIND_01011 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPPDDIND_01012 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
PPPDDIND_01013 0.0 pepN 3.4.11.2 E aminopeptidase
PPPDDIND_01014 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PPPDDIND_01016 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
PPPDDIND_01017 1.2e-07
PPPDDIND_01018 3.2e-08
PPPDDIND_01019 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PPPDDIND_01020 4.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PPPDDIND_01021 8.1e-177 malR K Transcriptional regulator
PPPDDIND_01022 3.2e-17 malX G ABC transporter
PPPDDIND_01023 3.8e-12 malX G maltose binding
PPPDDIND_01024 2.3e-27 malX G maltose binding
PPPDDIND_01025 2.6e-53 malF P ABC transporter (Permease
PPPDDIND_01026 1.3e-46 malF P ABC transporter (Permease
PPPDDIND_01027 4.6e-25 tatA U protein secretion
PPPDDIND_01028 2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PPPDDIND_01029 8.5e-263 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PPPDDIND_01030 1.5e-233 ycdB P peroxidase
PPPDDIND_01031 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
PPPDDIND_01032 2.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
PPPDDIND_01033 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
PPPDDIND_01034 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPPDDIND_01035 1.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPPDDIND_01036 5.5e-36 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPDDIND_01037 2e-222 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPDDIND_01038 4.1e-53 L Transposase
PPPDDIND_01039 3.4e-149 L Transposase
PPPDDIND_01040 1.6e-25
PPPDDIND_01041 1.1e-26 fic D Fic/DOC family
PPPDDIND_01042 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_01044 3.2e-19 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPPDDIND_01045 2e-103 L nUDIX hydrolase
PPPDDIND_01046 3.2e-172 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPPDDIND_01047 6.7e-156 K Transcriptional activator, Rgg GadR MutR family
PPPDDIND_01048 4.6e-238 L Transposase
PPPDDIND_01049 3.8e-69 3.2.1.17 M lysozyme activity
PPPDDIND_01050 2.8e-19 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPDDIND_01051 0.0 lpdA 1.8.1.4 C Dehydrogenase
PPPDDIND_01052 2.1e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PPPDDIND_01053 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PPPDDIND_01054 4.6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PPPDDIND_01055 4.6e-38 P membrane protein (DUF2207)
PPPDDIND_01056 9.7e-65 S the current gene model (or a revised gene model) may contain a frame shift
PPPDDIND_01057 2.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PPPDDIND_01058 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PPPDDIND_01059 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPPDDIND_01060 2.4e-23 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PPPDDIND_01061 5.3e-178 3.4.16.4 M Belongs to the peptidase S11 family
PPPDDIND_01062 1.3e-159 rssA S Phospholipase, patatin family
PPPDDIND_01063 4.6e-85 estA E GDSL-like protein
PPPDDIND_01064 5.2e-295 S unusual protein kinase
PPPDDIND_01065 1.3e-39 S granule-associated protein
PPPDDIND_01066 1.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPDDIND_01067 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
PPPDDIND_01068 5.1e-101 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPDDIND_01069 4.1e-29 bglH 3.2.1.86 GT1 G beta-glucosidase activity
PPPDDIND_01070 7.7e-200 S hmm pf01594
PPPDDIND_01071 1.4e-87 G Belongs to the phosphoglycerate mutase family
PPPDDIND_01072 1.9e-68 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
PPPDDIND_01073 3.5e-88 L Transposase
PPPDDIND_01074 1.9e-112 L Transposase
PPPDDIND_01075 1.6e-58 waaB GT4 M Glycosyl transferases group 1
PPPDDIND_01076 2.3e-67 tnp L DDE domain
PPPDDIND_01077 3.2e-08 tnp L DDE domain
PPPDDIND_01078 5.6e-90 V VanZ like family
PPPDDIND_01079 4e-105 cps2J S Polysaccharide biosynthesis protein
PPPDDIND_01080 2e-52 yxaB GM Polysaccharide pyruvyl transferase
PPPDDIND_01081 2.2e-35 S Core-2 I-Branching enzyme
PPPDDIND_01082 1.6e-32 S EpsG family
PPPDDIND_01083 2.3e-59 S Glycosyltransferase like family 2
PPPDDIND_01084 9e-33 epsH S Hexapeptide repeat of succinyl-transferase
PPPDDIND_01085 2.3e-63 2.4.1.21 GT4,GT5 G Glycosyl transferase 4-like domain
PPPDDIND_01086 2.9e-83 M Glycosyl transferase 4-like
PPPDDIND_01088 2.7e-59 rfbP 2.7.8.6 M Bacterial sugar transferase
PPPDDIND_01089 8.6e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
PPPDDIND_01090 7.2e-100 cps4C M biosynthesis protein
PPPDDIND_01091 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PPPDDIND_01092 7.4e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PPPDDIND_01093 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PPPDDIND_01094 3.1e-93 yfeJ 6.3.5.2 F glutamine amidotransferase
PPPDDIND_01095 6.8e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PPPDDIND_01096 2.9e-88 S Protein of unknown function (DUF1697)
PPPDDIND_01097 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PPPDDIND_01098 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PPPDDIND_01099 5.7e-08 V Glucan-binding protein C
PPPDDIND_01100 3e-32 V Glucan-binding protein C
PPPDDIND_01101 3.4e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
PPPDDIND_01102 2.4e-275 pepV 3.5.1.18 E Dipeptidase
PPPDDIND_01103 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PPPDDIND_01104 6.9e-86 XK27_03610 K Gnat family
PPPDDIND_01105 1.6e-24 L Transposase
PPPDDIND_01106 5.8e-42 L Transposase
PPPDDIND_01107 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PPPDDIND_01108 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PPPDDIND_01109 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PPPDDIND_01110 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PPPDDIND_01111 8.2e-18 M LysM domain
PPPDDIND_01112 2.9e-90 ebsA S Family of unknown function (DUF5322)
PPPDDIND_01113 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PPPDDIND_01114 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PPPDDIND_01115 4.9e-224 G COG0457 FOG TPR repeat
PPPDDIND_01116 6.2e-176 yubA S permease
PPPDDIND_01117 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PPPDDIND_01118 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PPPDDIND_01119 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PPPDDIND_01120 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PPPDDIND_01121 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PPPDDIND_01122 1.3e-181 yjjH S Calcineurin-like phosphoesterase
PPPDDIND_01123 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PPPDDIND_01124 0.0 pacL 3.6.3.8 P cation transport ATPase
PPPDDIND_01125 2.6e-67 ywiB S Domain of unknown function (DUF1934)
PPPDDIND_01126 1.7e-51 XK27_00115 2.3.1.128 K acetyltransferase
PPPDDIND_01127 9.2e-147 yidA S hydrolases of the HAD superfamily
PPPDDIND_01128 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PPPDDIND_01129 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PPPDDIND_01130 3.9e-235 vicK 2.7.13.3 T Histidine kinase
PPPDDIND_01131 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPDDIND_01132 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_01133 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PPPDDIND_01134 2.7e-118 gltJ P ABC transporter (Permease
PPPDDIND_01135 5e-111 tcyB_2 P ABC transporter (permease)
PPPDDIND_01136 2e-142 endA F DNA RNA non-specific endonuclease
PPPDDIND_01137 1.6e-25 epuA S DNA-directed RNA polymerase subunit beta
PPPDDIND_01138 1.7e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPPDDIND_01140 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPDDIND_01141 7e-27 G Domain of unknown function (DUF4832)
PPPDDIND_01142 1.3e-202 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PPPDDIND_01143 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PPPDDIND_01145 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPPDDIND_01146 2.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
PPPDDIND_01147 6.4e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PPPDDIND_01148 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
PPPDDIND_01151 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PPPDDIND_01152 1.4e-218 XK27_05110 P chloride
PPPDDIND_01153 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PPPDDIND_01154 1.1e-281 clcA P Chloride transporter, ClC family
PPPDDIND_01155 5.1e-75 fld C Flavodoxin
PPPDDIND_01156 2.5e-14 XK27_08880
PPPDDIND_01157 1e-125 XK27_08875 O Zinc-dependent metalloprotease
PPPDDIND_01158 3.5e-151 estA CE1 S Putative esterase
PPPDDIND_01159 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPPDDIND_01160 5.8e-135 XK27_08845 S abc transporter atp-binding protein
PPPDDIND_01161 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PPPDDIND_01162 7.3e-178 XK27_08835 S ABC transporter substrate binding protein
PPPDDIND_01163 3.2e-17 S Domain of unknown function (DUF4649)
PPPDDIND_01165 9.6e-43 Q the current gene model (or a revised gene model) may contain a frame shift
PPPDDIND_01166 5.4e-27 Q the current gene model (or a revised gene model) may contain a frame shift
PPPDDIND_01168 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
PPPDDIND_01170 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PPPDDIND_01171 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PPPDDIND_01172 0.0 dnaE 2.7.7.7 L DNA polymerase
PPPDDIND_01173 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
PPPDDIND_01174 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPPDDIND_01175 8.9e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPPDDIND_01176 1.1e-41 ysdA L Membrane
PPPDDIND_01177 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PPPDDIND_01178 7.6e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PPPDDIND_01179 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PPPDDIND_01180 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_01181 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PPPDDIND_01183 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PPPDDIND_01184 6.8e-96 ypmS S Protein conserved in bacteria
PPPDDIND_01185 3.8e-146 ypmR E lipolytic protein G-D-S-L family
PPPDDIND_01186 1.7e-148 DegV S DegV family
PPPDDIND_01187 1.3e-304 recN L May be involved in recombinational repair of damaged DNA
PPPDDIND_01188 7.5e-74 argR K arginine binding
PPPDDIND_01189 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PPPDDIND_01190 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PPPDDIND_01191 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
PPPDDIND_01192 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPPDDIND_01195 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PPPDDIND_01196 2.9e-125 dnaD
PPPDDIND_01197 3.5e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PPPDDIND_01198 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PPPDDIND_01199 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PPPDDIND_01200 3e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPDDIND_01201 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PPPDDIND_01202 7.9e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PPPDDIND_01203 9.2e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PPPDDIND_01204 6.2e-239 rodA D Belongs to the SEDS family
PPPDDIND_01205 4.4e-68 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PPPDDIND_01206 1.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PPPDDIND_01207 2.2e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PPPDDIND_01208 1.8e-121 ylfI S tigr01906
PPPDDIND_01209 1.7e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PPPDDIND_01210 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
PPPDDIND_01211 1.3e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
PPPDDIND_01215 2.1e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PPPDDIND_01216 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PPPDDIND_01217 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PPPDDIND_01218 4.8e-207 yurR 1.4.5.1 E oxidoreductase
PPPDDIND_01219 1.7e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
PPPDDIND_01220 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
PPPDDIND_01221 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PPPDDIND_01222 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PPPDDIND_01223 1.1e-69 gtrA S GtrA-like protein
PPPDDIND_01224 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PPPDDIND_01225 6e-169 ybbR S Protein conserved in bacteria
PPPDDIND_01226 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PPPDDIND_01227 8.3e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PPPDDIND_01228 8.7e-150 cobQ S glutamine amidotransferase
PPPDDIND_01229 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PPPDDIND_01230 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
PPPDDIND_01231 0.0 uup S abc transporter atp-binding protein
PPPDDIND_01232 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
PPPDDIND_01233 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
PPPDDIND_01234 2.4e-19 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPPDDIND_01235 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PPPDDIND_01236 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PPPDDIND_01237 7.9e-39 ptsH G phosphocarrier protein Hpr
PPPDDIND_01238 2.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
PPPDDIND_01239 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
PPPDDIND_01240 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PPPDDIND_01241 2.2e-34 nrdH O Glutaredoxin
PPPDDIND_01242 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPPDDIND_01243 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPPDDIND_01245 1.1e-74 L Transposase (IS116 IS110 IS902 family)
PPPDDIND_01246 5.5e-65 L Transposase (IS116 IS110 IS902 family)
PPPDDIND_01247 1.8e-165 ypuA S secreted protein
PPPDDIND_01248 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
PPPDDIND_01249 4.6e-58 srtA 3.4.22.70 M Sortase family
PPPDDIND_01250 5.8e-18 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PPPDDIND_01251 5.7e-33 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PPPDDIND_01252 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPPDDIND_01253 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PPPDDIND_01254 2.6e-258 noxE P NADH oxidase
PPPDDIND_01255 2.8e-293 yfmM S abc transporter atp-binding protein
PPPDDIND_01256 5.4e-46 XK27_01265 S ECF-type riboflavin transporter, S component
PPPDDIND_01257 5.4e-09 XK27_01265 S ECF-type riboflavin transporter, S component
PPPDDIND_01258 5.5e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PPPDDIND_01259 2e-86 S ECF-type riboflavin transporter, S component
PPPDDIND_01261 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPPDDIND_01262 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PPPDDIND_01265 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPPDDIND_01266 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPPDDIND_01267 3.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PPPDDIND_01268 0.0 smc D Required for chromosome condensation and partitioning
PPPDDIND_01269 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PPPDDIND_01270 3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PPPDDIND_01271 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PPPDDIND_01272 2.6e-88 alkD L Dna alkylation repair
PPPDDIND_01273 1.6e-91 pat 2.3.1.183 M acetyltransferase
PPPDDIND_01274 7.3e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PPPDDIND_01275 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PPPDDIND_01276 8.2e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PPPDDIND_01277 4e-64 bioY S biotin transmembrane transporter activity
PPPDDIND_01278 3.6e-90 proW P Binding-protein-dependent transport system inner membrane component
PPPDDIND_01279 1.5e-138 proV E abc transporter atp-binding protein
PPPDDIND_01280 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
PPPDDIND_01281 1.7e-111 proWZ P ABC transporter (Permease
PPPDDIND_01282 1.4e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
PPPDDIND_01283 5.4e-206 S Protein of unknown function (DUF917)
PPPDDIND_01284 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PPPDDIND_01285 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
PPPDDIND_01286 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase
PPPDDIND_01287 3.3e-26
PPPDDIND_01288 2.9e-145 S ABC-2 family transporter protein
PPPDDIND_01289 6.6e-99 S transport system, permease component
PPPDDIND_01290 6.1e-103 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPPDDIND_01291 2.5e-187 desK 2.7.13.3 T Histidine kinase
PPPDDIND_01292 4.8e-134 yvfS V ABC-2 type transporter
PPPDDIND_01293 2.3e-159 XK27_09825 V abc transporter atp-binding protein
PPPDDIND_01296 1.8e-165 yocS S Transporter
PPPDDIND_01297 2.4e-80 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PPPDDIND_01298 2.9e-34 XK27_05000 S metal cluster binding
PPPDDIND_01299 0.0 V ABC transporter (permease)
PPPDDIND_01300 1.9e-133 macB2 V ABC transporter, ATP-binding protein
PPPDDIND_01301 2.1e-166 T Histidine kinase
PPPDDIND_01302 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPDDIND_01303 7.8e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PPPDDIND_01304 1.4e-74 pbuX F xanthine permease
PPPDDIND_01305 7.1e-125 pbuX F xanthine permease
PPPDDIND_01306 1.2e-165 L integrase core domain
PPPDDIND_01307 3.9e-122 L Transposase
PPPDDIND_01308 7.2e-245 norM V Multidrug efflux pump
PPPDDIND_01309 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPPDDIND_01310 2.9e-84 yxeM ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_01311 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
PPPDDIND_01312 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_01313 4.1e-63 yxeN U ABC transporter, permease protein
PPPDDIND_01314 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
PPPDDIND_01315 3e-115 yxeQ S MmgE/PrpD family
PPPDDIND_01316 1.1e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PPPDDIND_01317 6.7e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PPPDDIND_01318 3.4e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PPPDDIND_01319 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PPPDDIND_01320 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PPPDDIND_01321 1.2e-233 brnQ E Component of the transport system for branched-chain amino acids
PPPDDIND_01322 1e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPDDIND_01323 2e-49 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPDDIND_01324 9.6e-26 csbD K CsbD-like
PPPDDIND_01325 6.2e-228 yfnA E amino acid
PPPDDIND_01326 2.5e-109 XK27_02070 S nitroreductase
PPPDDIND_01327 2.2e-90 1.13.11.2 S glyoxalase
PPPDDIND_01328 5.6e-77 ywnA K Transcriptional regulator
PPPDDIND_01329 1.9e-158 E Alpha/beta hydrolase of unknown function (DUF915)
PPPDDIND_01330 2.3e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPPDDIND_01331 2.9e-111 drgA C Nitroreductase
PPPDDIND_01332 3.5e-87 yoaK S Protein of unknown function (DUF1275)
PPPDDIND_01334 1.2e-160 yvgN C reductase
PPPDDIND_01335 3.9e-104 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPDDIND_01336 7.8e-285 XK27_07020 S Belongs to the UPF0371 family
PPPDDIND_01338 9.6e-37 BP1961 P nitric oxide dioxygenase activity
PPPDDIND_01339 2.4e-54 K response regulator
PPPDDIND_01340 1.1e-69 S Signal peptide protein, YSIRK family
PPPDDIND_01342 5e-60
PPPDDIND_01343 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPDDIND_01344 4.1e-139
PPPDDIND_01345 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
PPPDDIND_01346 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
PPPDDIND_01347 5.8e-109 MA20_06410 E LysE type translocator
PPPDDIND_01348 2.7e-09
PPPDDIND_01349 0.0 M family 8
PPPDDIND_01350 3.8e-21
PPPDDIND_01351 0.0 sbcC L ATPase involved in DNA repair
PPPDDIND_01352 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PPPDDIND_01353 0.0 lacL 3.2.1.23 G -beta-galactosidase
PPPDDIND_01354 0.0 lacS G transporter
PPPDDIND_01355 3.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PPPDDIND_01356 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPDDIND_01357 6.8e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PPPDDIND_01358 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PPPDDIND_01359 2.3e-184 galR K Transcriptional regulator
PPPDDIND_01360 7.1e-09 L Integrase core domain protein
PPPDDIND_01361 1.2e-25 L transposition
PPPDDIND_01362 3e-198 M translation initiation factor activity
PPPDDIND_01363 4.6e-68 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
PPPDDIND_01364 1.3e-76 V abc transporter atp-binding protein
PPPDDIND_01365 1e-41 V (ABC) transporter
PPPDDIND_01366 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PPPDDIND_01367 2.3e-87 L Transposase
PPPDDIND_01368 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PPPDDIND_01369 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PPPDDIND_01370 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PPPDDIND_01371 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PPPDDIND_01374 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPPDDIND_01375 1.7e-174 vraS 2.7.13.3 T Histidine kinase
PPPDDIND_01376 3.7e-120 yvqF KT membrane
PPPDDIND_01377 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PPPDDIND_01378 2e-132 stp 3.1.3.16 T phosphatase
PPPDDIND_01379 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PPPDDIND_01380 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PPPDDIND_01381 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PPPDDIND_01382 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PPPDDIND_01383 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PPPDDIND_01384 1.8e-219 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PPPDDIND_01385 3.8e-148 XK27_02985 S overlaps another CDS with the same product name
PPPDDIND_01386 3.1e-147 supH S overlaps another CDS with the same product name
PPPDDIND_01387 8.6e-63 yvoA_1 K Transcriptional
PPPDDIND_01388 9.8e-121 skfE V abc transporter atp-binding protein
PPPDDIND_01389 3.3e-133 V ATPase activity
PPPDDIND_01390 4.3e-172 oppF P Belongs to the ABC transporter superfamily
PPPDDIND_01391 2.2e-204 oppD P Belongs to the ABC transporter superfamily
PPPDDIND_01392 4.9e-168 amiD P ABC transporter (Permease
PPPDDIND_01393 2.1e-277 amiC P ABC transporter (Permease
PPPDDIND_01394 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PPPDDIND_01395 4.6e-13 L Transposase
PPPDDIND_01396 1.5e-191 L Transposase
PPPDDIND_01397 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PPPDDIND_01398 1.2e-24 oppF P Belongs to the ABC transporter superfamily
PPPDDIND_01399 2e-46 oppF P Belongs to the ABC transporter superfamily
PPPDDIND_01400 4e-40 tatD L Hydrolase, tatd
PPPDDIND_01401 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
PPPDDIND_01402 7.5e-109 L PFAM Integrase catalytic region
PPPDDIND_01403 6e-28 L transposition
PPPDDIND_01404 7.2e-22 L Transposase
PPPDDIND_01405 7.4e-39 L transposase activity
PPPDDIND_01406 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PPPDDIND_01407 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PPPDDIND_01408 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PPPDDIND_01409 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PPPDDIND_01410 1.5e-103 yjbK S Adenylate cyclase
PPPDDIND_01411 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPPDDIND_01412 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
PPPDDIND_01413 3.1e-59 XK27_04120 S Putative amino acid metabolism
PPPDDIND_01414 8.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PPPDDIND_01415 8.8e-130 puuD T peptidase C26
PPPDDIND_01416 1.4e-119 radC E Belongs to the UPF0758 family
PPPDDIND_01417 2.5e-267 M Psort location CytoplasmicMembrane, score
PPPDDIND_01418 0.0 rgpF M Rhamnan synthesis protein F
PPPDDIND_01419 3.8e-304 GT4 M transferase activity, transferring glycosyl groups
PPPDDIND_01420 8.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PPPDDIND_01421 8e-143 rgpC GM Transport permease protein
PPPDDIND_01422 2.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
PPPDDIND_01423 1e-223 rgpA GT4 M Domain of unknown function (DUF1972)
PPPDDIND_01424 1.3e-105 2.4.1.60 S Glycosyltransferase group 2 family protein
PPPDDIND_01425 2.6e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
PPPDDIND_01426 2.2e-125 ycbB S Glycosyl transferase family 2
PPPDDIND_01427 4.6e-39 arnC M group 2 family protein
PPPDDIND_01428 1.9e-141 M Glycosyltransferase group 2 family protein
PPPDDIND_01429 4.4e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
PPPDDIND_01430 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PPPDDIND_01431 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PPPDDIND_01432 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PPPDDIND_01433 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PPPDDIND_01434 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PPPDDIND_01435 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PPPDDIND_01436 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_01437 1.4e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_01438 2.8e-202 arcT 2.6.1.1 E Aminotransferase
PPPDDIND_01439 7.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_01440 1.3e-143 ET Belongs to the bacterial solute-binding protein 3 family
PPPDDIND_01441 2.2e-84 mutT 3.6.1.55 F Nudix family
PPPDDIND_01442 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PPPDDIND_01443 2.9e-57 V CAAX protease self-immunity
PPPDDIND_01444 7.6e-32 S CAAX amino terminal protease family protein
PPPDDIND_01445 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PPPDDIND_01446 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_01447 1.1e-16 XK27_00735
PPPDDIND_01448 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PPPDDIND_01450 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPDDIND_01453 2.3e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
PPPDDIND_01454 7.7e-52 V Psort location Cytoplasmic, score
PPPDDIND_01455 2.3e-156 K sequence-specific DNA binding
PPPDDIND_01456 8.9e-253 C Arylsulfatase regulator (Fe-S oxidoreductase)
PPPDDIND_01457 9.4e-289 V (ABC) transporter
PPPDDIND_01458 9.6e-10
PPPDDIND_01459 1.9e-43 S Domain of unknown function (DUF4299)
PPPDDIND_01460 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
PPPDDIND_01461 5.9e-155 EG Permeases of the drug metabolite transporter (DMT) superfamily
PPPDDIND_01463 3.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
PPPDDIND_01464 3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PPPDDIND_01465 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPPDDIND_01466 2.6e-109 3.1.3.18 S IA, variant 1
PPPDDIND_01467 2.2e-117 lrgB M effector of murein hydrolase
PPPDDIND_01468 2.2e-58 lrgA S Effector of murein hydrolase LrgA
PPPDDIND_01470 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
PPPDDIND_01471 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PPPDDIND_01472 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PPPDDIND_01473 1.3e-104 wecD M Acetyltransferase (GNAT) domain
PPPDDIND_01474 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PPPDDIND_01475 5.4e-116 GK ROK family
PPPDDIND_01476 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
PPPDDIND_01477 1e-115 XK27_08050 O HflC and HflK could regulate a protease
PPPDDIND_01479 2.3e-206 potD P spermidine putrescine ABC transporter
PPPDDIND_01480 4.3e-133 potC P ABC-type spermidine putrescine transport system, permease component II
PPPDDIND_01481 1.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
PPPDDIND_01482 3.6e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PPPDDIND_01483 4.6e-171 murB 1.3.1.98 M cell wall formation
PPPDDIND_01484 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PPPDDIND_01485 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PPPDDIND_01486 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PPPDDIND_01487 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PPPDDIND_01488 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
PPPDDIND_01489 0.0 ydaO E amino acid
PPPDDIND_01490 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PPPDDIND_01491 4.1e-37 ylqC L Belongs to the UPF0109 family
PPPDDIND_01492 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PPPDDIND_01493 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PPPDDIND_01494 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
PPPDDIND_01495 2.8e-74 S QueT transporter
PPPDDIND_01496 5.2e-121 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PPPDDIND_01497 4.3e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PPPDDIND_01498 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PPPDDIND_01499 1.3e-85 ccl S cog cog4708
PPPDDIND_01500 6.5e-160 rbn E Belongs to the UPF0761 family
PPPDDIND_01501 5.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PPPDDIND_01502 1.7e-232 ytoI K transcriptional regulator containing CBS domains
PPPDDIND_01503 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PPPDDIND_01504 1.2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPPDDIND_01505 0.0 comEC S Competence protein ComEC
PPPDDIND_01506 4e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PPPDDIND_01507 1.3e-142 plsC 2.3.1.51 I Acyltransferase
PPPDDIND_01508 1.4e-82 nodB3 G polysaccharide deacetylase
PPPDDIND_01509 4.1e-49 nodB3 G polysaccharide deacetylase
PPPDDIND_01510 9.3e-141 yabB 2.1.1.223 L Methyltransferase
PPPDDIND_01511 1e-41 yazA L endonuclease containing a URI domain
PPPDDIND_01512 2.8e-256 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PPPDDIND_01513 1.1e-153 corA P CorA-like protein
PPPDDIND_01514 2.5e-62 yjqA S Bacterial PH domain
PPPDDIND_01515 7.8e-100 thiT S Thiamine transporter
PPPDDIND_01516 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPDDIND_01517 3.2e-201 yjbB G Permeases of the major facilitator superfamily
PPPDDIND_01518 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PPPDDIND_01519 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
PPPDDIND_01520 3.6e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PPPDDIND_01523 8.8e-156 cjaA ET ABC transporter substrate-binding protein
PPPDDIND_01524 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_01525 7.8e-107 P ABC transporter (Permease
PPPDDIND_01526 6e-115 papP P ABC transporter (Permease
PPPDDIND_01527 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPPDDIND_01528 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PPPDDIND_01529 0.0 copA 3.6.3.54 P P-type ATPase
PPPDDIND_01530 3.2e-74 copY K negative regulation of transcription, DNA-templated
PPPDDIND_01531 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PPPDDIND_01532 3.5e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PPPDDIND_01533 1.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PPPDDIND_01534 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PPPDDIND_01535 3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PPPDDIND_01536 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PPPDDIND_01537 2.5e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PPPDDIND_01538 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
PPPDDIND_01539 3.2e-56
PPPDDIND_01540 0.0 ctpE P E1-E2 ATPase
PPPDDIND_01541 6.1e-27
PPPDDIND_01542 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PPPDDIND_01543 1.9e-46 L transposase activity
PPPDDIND_01544 9.9e-115 K transcriptional regulator, MerR family
PPPDDIND_01545 3.7e-105 dnaQ 2.7.7.7 L DNA polymerase III
PPPDDIND_01546 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
PPPDDIND_01547 4.8e-63 XK27_02560 S cog cog2151
PPPDDIND_01548 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPDDIND_01549 7.7e-227 ytfP S Flavoprotein
PPPDDIND_01551 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PPPDDIND_01552 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
PPPDDIND_01553 3.9e-182 ecsB U ABC transporter
PPPDDIND_01554 2.3e-133 ecsA V abc transporter atp-binding protein
PPPDDIND_01555 4.3e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PPPDDIND_01556 6.2e-11
PPPDDIND_01557 3.2e-110
PPPDDIND_01559 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PPPDDIND_01560 1.3e-204 ylbM S Belongs to the UPF0348 family
PPPDDIND_01561 7.7e-140 yqeM Q Methyltransferase domain protein
PPPDDIND_01562 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PPPDDIND_01563 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PPPDDIND_01564 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PPPDDIND_01565 3.5e-49 yhbY J RNA-binding protein
PPPDDIND_01566 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PPPDDIND_01567 1.8e-98 yqeG S hydrolase of the HAD superfamily
PPPDDIND_01568 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PPPDDIND_01569 1.4e-65
PPPDDIND_01570 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPPDDIND_01571 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PPPDDIND_01572 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPPDDIND_01573 4.4e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
PPPDDIND_01574 7.4e-32 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PPPDDIND_01575 3.8e-96 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPDDIND_01576 1.2e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPDDIND_01577 7.9e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPPDDIND_01578 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
PPPDDIND_01579 6.8e-101 pncA Q isochorismatase
PPPDDIND_01580 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PPPDDIND_01581 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PPPDDIND_01582 2.4e-75 XK27_03180 T universal stress protein
PPPDDIND_01584 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPPDDIND_01585 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PPPDDIND_01586 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PPPDDIND_01587 0.0 yjcE P NhaP-type Na H and K H antiporters
PPPDDIND_01589 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
PPPDDIND_01590 1.3e-184 yhcC S radical SAM protein
PPPDDIND_01591 2.2e-196 ylbL T Belongs to the peptidase S16 family
PPPDDIND_01592 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PPPDDIND_01593 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
PPPDDIND_01594 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PPPDDIND_01595 2.8e-08 S Protein of unknown function (DUF4059)
PPPDDIND_01596 3.4e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
PPPDDIND_01597 3.4e-172 yxeN P ABC transporter (Permease
PPPDDIND_01598 2.6e-149 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PPPDDIND_01600 6.5e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPDDIND_01601 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PPPDDIND_01602 2.2e-122 cah 4.2.1.1 P carbonic anhydrase
PPPDDIND_01603 8.4e-37 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPPDDIND_01604 5.6e-33 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPPDDIND_01605 7.1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
PPPDDIND_01606 3.4e-32 D nuclear chromosome segregation
PPPDDIND_01607 4.1e-80 L DNA integration
PPPDDIND_01608 7.1e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
PPPDDIND_01609 1.5e-127 ybbM S transport system, permease component
PPPDDIND_01610 2.7e-117 ybbL S abc transporter atp-binding protein
PPPDDIND_01611 3.1e-31
PPPDDIND_01612 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PPPDDIND_01613 4.6e-140 cppA E CppA N-terminal
PPPDDIND_01614 9.4e-183 L Transposase and inactivated derivatives IS30 family
PPPDDIND_01615 9.1e-30 V CAAX protease self-immunity
PPPDDIND_01616 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PPPDDIND_01617 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PPPDDIND_01619 6.4e-88 L Transposase
PPPDDIND_01620 1.2e-165 L integrase core domain
PPPDDIND_01622 8.9e-133 agrA KT phosphorelay signal transduction system
PPPDDIND_01623 3.8e-238 blpH 2.7.13.3 T protein histidine kinase activity
PPPDDIND_01625 1.7e-126 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPDDIND_01626 2.7e-44 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPDDIND_01627 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPDDIND_01629 0.0 mdlB V abc transporter atp-binding protein
PPPDDIND_01630 0.0 mdlA V abc transporter atp-binding protein
PPPDDIND_01632 1.5e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
PPPDDIND_01633 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PPPDDIND_01634 2.3e-72 yutD J protein conserved in bacteria
PPPDDIND_01635 1.1e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PPPDDIND_01637 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PPPDDIND_01638 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PPPDDIND_01639 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PPPDDIND_01640 5.6e-47 ftsL D cell division protein FtsL
PPPDDIND_01641 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PPPDDIND_01642 4e-54
PPPDDIND_01643 8e-31
PPPDDIND_01644 2.1e-10
PPPDDIND_01646 6.3e-31 yhaI J Protein of unknown function (DUF805)
PPPDDIND_01647 3.5e-10 D nuclear chromosome segregation
PPPDDIND_01648 6.9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PPPDDIND_01649 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PPPDDIND_01650 4e-287 XK27_00765
PPPDDIND_01651 1.1e-89 ecsA_2 V abc transporter atp-binding protein
PPPDDIND_01652 2e-45 ecsA_2 V ATPase activity
PPPDDIND_01653 1.5e-104 S Protein of unknown function (DUF554)
PPPDDIND_01654 1.6e-11 S Protein of unknown function (DUF554)
PPPDDIND_01655 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PPPDDIND_01656 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PPPDDIND_01657 2.6e-66 liaI S membrane
PPPDDIND_01658 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
PPPDDIND_01659 6.5e-68 KT response to antibiotic
PPPDDIND_01660 9.1e-18 KT response to antibiotic
PPPDDIND_01661 1.7e-79 yebC M Membrane
PPPDDIND_01662 8.5e-18 yebC M Membrane
PPPDDIND_01663 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
PPPDDIND_01664 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PPPDDIND_01665 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PPPDDIND_01666 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PPPDDIND_01667 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PPPDDIND_01668 1.2e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPPDDIND_01669 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPPDDIND_01670 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PPPDDIND_01672 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPDDIND_01673 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PPPDDIND_01674 0.0 scrA 2.7.1.211 G pts system
PPPDDIND_01675 4.1e-291 scrB 3.2.1.26 GH32 G invertase
PPPDDIND_01676 6.4e-179 scrR K Transcriptional
PPPDDIND_01677 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PPPDDIND_01678 3.4e-62 yqhY S protein conserved in bacteria
PPPDDIND_01679 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PPPDDIND_01680 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
PPPDDIND_01681 4.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PPPDDIND_01684 1.9e-44 V 'abc transporter, ATP-binding protein
PPPDDIND_01685 4.3e-36 V 'abc transporter, ATP-binding protein
PPPDDIND_01688 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PPPDDIND_01689 5.8e-169 corA P COG0598 Mg2 and Co2 transporters
PPPDDIND_01690 2e-123 XK27_01040 S Pfam PF06570
PPPDDIND_01692 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PPPDDIND_01693 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PPPDDIND_01694 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PPPDDIND_01696 2.8e-28 XK27_05745
PPPDDIND_01697 4.2e-230 mutY L A G-specific adenine glycosylase
PPPDDIND_01700 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PPPDDIND_01701 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PPPDDIND_01702 3e-93 cvpA S toxin biosynthetic process
PPPDDIND_01703 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PPPDDIND_01704 1.8e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPPDDIND_01705 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PPPDDIND_01706 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PPPDDIND_01707 8.8e-48 azlD E branched-chain amino acid
PPPDDIND_01708 3.8e-117 azlC E AzlC protein
PPPDDIND_01709 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PPPDDIND_01710 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PPPDDIND_01711 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PPPDDIND_01712 2.5e-33 ykzG S Belongs to the UPF0356 family
PPPDDIND_01713 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPPDDIND_01714 7.6e-263 glnA 6.3.1.2 E glutamine synthetase
PPPDDIND_01715 8.5e-63 glnR K Transcriptional regulator
PPPDDIND_01716 1.3e-87 S Fusaric acid resistance protein-like
PPPDDIND_01717 8.7e-38 L Transposase
PPPDDIND_01718 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PPPDDIND_01719 5.5e-42 L Transposase
PPPDDIND_01720 9.4e-46 L transposase activity
PPPDDIND_01721 2.5e-22 L Transposase
PPPDDIND_01722 4.2e-53 L transposition
PPPDDIND_01723 4.5e-88 L Integrase core domain protein
PPPDDIND_01724 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PPPDDIND_01725 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PPPDDIND_01726 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PPPDDIND_01727 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PPPDDIND_01728 2.4e-142 purR 2.4.2.7 F operon repressor
PPPDDIND_01729 5.3e-178 cbf S 3'-5' exoribonuclease yhaM
PPPDDIND_01730 6.9e-173 rmuC S RmuC domain protein
PPPDDIND_01731 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
PPPDDIND_01732 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PPPDDIND_01733 1.2e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PPPDDIND_01735 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PPPDDIND_01736 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PPPDDIND_01737 1.4e-144 tatD L Hydrolase, tatd
PPPDDIND_01738 1.5e-74 yccU S CoA-binding protein
PPPDDIND_01739 4.8e-51 trxA O Belongs to the thioredoxin family
PPPDDIND_01740 7.8e-143 S Macro domain protein
PPPDDIND_01741 9.1e-10 L thioesterase
PPPDDIND_01742 3.2e-53 bta 1.8.1.8 CO cell redox homeostasis
PPPDDIND_01745 4.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PPPDDIND_01746 1.6e-87 L Transposase
PPPDDIND_01747 1e-13 rpmH J Ribosomal protein L34
PPPDDIND_01748 3.8e-185 jag S RNA-binding protein
PPPDDIND_01749 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPPDDIND_01750 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PPPDDIND_01751 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
PPPDDIND_01752 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PPPDDIND_01753 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PPPDDIND_01754 1.4e-81 amiA E transmembrane transport
PPPDDIND_01755 4.9e-75 amiA E transmembrane transport
PPPDDIND_01756 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PPPDDIND_01757 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PPPDDIND_01758 9.2e-51 S Protein of unknown function (DUF3397)
PPPDDIND_01759 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PPPDDIND_01760 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
PPPDDIND_01761 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
PPPDDIND_01762 4.8e-227 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PPPDDIND_01763 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PPPDDIND_01764 4.1e-65 XK27_09620 S FMN reductase (NADPH) activity
PPPDDIND_01765 8.3e-34 XK27_09620 S FMN reductase (NADPH) activity
PPPDDIND_01766 6.6e-34 XK27_09615 S FMN reductase (NADPH) activity
PPPDDIND_01767 1.9e-132 XK27_09615 S PAS domain
PPPDDIND_01768 1.1e-07 fnt P Formate nitrite transporter
PPPDDIND_01769 2.9e-63 fnt P Formate nitrite transporter
PPPDDIND_01770 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
PPPDDIND_01771 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PPPDDIND_01772 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PPPDDIND_01773 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PPPDDIND_01774 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PPPDDIND_01775 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PPPDDIND_01776 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PPPDDIND_01777 2.7e-48 S glycolate biosynthetic process
PPPDDIND_01778 4e-65 S phosphatase activity
PPPDDIND_01779 2.4e-158 rrmA 2.1.1.187 Q methyltransferase
PPPDDIND_01781 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PPPDDIND_01782 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PPPDDIND_01783 9.2e-36 yeeD O sulfur carrier activity
PPPDDIND_01784 1.9e-189 yeeE S Sulphur transport
PPPDDIND_01785 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPPDDIND_01786 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PPPDDIND_01787 7e-09 S Domain of unknown function (DUF4651)
PPPDDIND_01788 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PPPDDIND_01789 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPPDDIND_01790 1.9e-110 S CAAX amino terminal protease family protein
PPPDDIND_01792 7.6e-68 V CAAX protease self-immunity
PPPDDIND_01793 8.8e-27 lanR K sequence-specific DNA binding
PPPDDIND_01794 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PPPDDIND_01795 5.9e-177 ytxK 2.1.1.72 L DNA methylase
PPPDDIND_01796 6.8e-13 comGF U Putative Competence protein ComGF
PPPDDIND_01797 4e-72 comGF U Competence protein ComGF
PPPDDIND_01798 1.4e-15 NU Type II secretory pathway pseudopilin
PPPDDIND_01799 1.8e-57 cglD NU Competence protein
PPPDDIND_01800 8.5e-43 comGC U Required for transformation and DNA binding
PPPDDIND_01801 9.2e-153 cglB NU type II secretion system
PPPDDIND_01802 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PPPDDIND_01803 1e-68 S cog cog4699
PPPDDIND_01804 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPDDIND_01805 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPDDIND_01806 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPDDIND_01807 2.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPPDDIND_01808 1.2e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PPPDDIND_01809 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
PPPDDIND_01810 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PPPDDIND_01811 3.3e-283 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPDDIND_01812 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPDDIND_01813 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
PPPDDIND_01814 1.4e-57 asp S cog cog1302
PPPDDIND_01815 8.4e-227 norM V Mate efflux family protein
PPPDDIND_01816 1.9e-278 thrC 4.2.3.1 E Threonine synthase
PPPDDIND_01817 1.4e-62 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPPDDIND_01818 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
PPPDDIND_01819 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPPDDIND_01820 7.4e-103 1.1.1.1, 1.1.99.1, 1.2.1.10, 1.2.1.18, 1.2.1.27, 1.2.1.3 C Dehydrogenase
PPPDDIND_01821 5.1e-66 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
PPPDDIND_01822 0.0 pepO 3.4.24.71 O Peptidase family M13
PPPDDIND_01823 2.3e-120 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPPDDIND_01824 7e-67 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPPDDIND_01825 2e-56 treB 2.7.1.201 G PTS System
PPPDDIND_01826 5.8e-21 treR K DNA-binding transcription factor activity
PPPDDIND_01827 2.3e-87 treR K trehalose operon
PPPDDIND_01828 5.7e-95 ywlG S Belongs to the UPF0340 family
PPPDDIND_01831 2.7e-13 L PFAM Integrase, catalytic core
PPPDDIND_01832 4e-75 L PFAM Integrase, catalytic core
PPPDDIND_01833 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PPPDDIND_01835 2.1e-111 6.3.2.2 H ergothioneine biosynthetic process
PPPDDIND_01836 1.1e-16 6.3.2.2 H gamma-glutamylcysteine synthetase
PPPDDIND_01837 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
PPPDDIND_01838 7.8e-32 L PFAM Integrase, catalytic core
PPPDDIND_01839 1.3e-71 L PFAM Integrase, catalytic core
PPPDDIND_01840 3.3e-62 rplQ J ribosomal protein l17
PPPDDIND_01841 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPDDIND_01842 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PPPDDIND_01843 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PPPDDIND_01844 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PPPDDIND_01845 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PPPDDIND_01846 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PPPDDIND_01847 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PPPDDIND_01848 7.4e-58 rplO J binds to the 23S rRNA
PPPDDIND_01849 2.5e-23 rpmD J ribosomal protein l30
PPPDDIND_01850 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PPPDDIND_01851 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PPPDDIND_01852 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PPPDDIND_01853 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PPPDDIND_01854 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPPDDIND_01855 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PPPDDIND_01856 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PPPDDIND_01857 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PPPDDIND_01858 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PPPDDIND_01859 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PPPDDIND_01860 3.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PPPDDIND_01861 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PPPDDIND_01862 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PPPDDIND_01863 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PPPDDIND_01864 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PPPDDIND_01865 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PPPDDIND_01866 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PPPDDIND_01867 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PPPDDIND_01868 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PPPDDIND_01869 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PPPDDIND_01870 0.0 XK27_09800 I Acyltransferase
PPPDDIND_01871 1.7e-35 XK27_09805 S MORN repeat protein
PPPDDIND_01872 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PPPDDIND_01873 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PPPDDIND_01874 8.9e-95 adk 2.7.4.3 F topology modulation protein
PPPDDIND_01875 3.1e-172 yxaM EGP Major facilitator Superfamily
PPPDDIND_01876 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
PPPDDIND_01877 6.3e-54 L Transposase
PPPDDIND_01878 4.1e-147 L Transposase
PPPDDIND_01880 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPDDIND_01881 0.0 KLT serine threonine protein kinase
PPPDDIND_01882 2.1e-280 V ABC transporter
PPPDDIND_01883 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPDDIND_01884 3.7e-128 Z012_04635 K sequence-specific DNA binding
PPPDDIND_01886 3.6e-232 C Radical SAM
PPPDDIND_01887 3.9e-287 V ABC transporter transmembrane region
PPPDDIND_01888 5.9e-156 L Replication initiation factor
PPPDDIND_01889 1.9e-18 S Domain of unknown function (DUF3173)
PPPDDIND_01890 3.5e-216 int L Belongs to the 'phage' integrase family
PPPDDIND_01892 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PPPDDIND_01893 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PPPDDIND_01894 2.2e-44 yrzL S Belongs to the UPF0297 family
PPPDDIND_01895 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PPPDDIND_01896 4.2e-44 yrzB S Belongs to the UPF0473 family
PPPDDIND_01897 3.5e-302 ccs S the current gene model (or a revised gene model) may contain a frame shift
PPPDDIND_01898 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PPPDDIND_01899 7.5e-14
PPPDDIND_01900 3.4e-91 XK27_10930 K acetyltransferase
PPPDDIND_01901 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPPDDIND_01902 1.3e-145 yaaA S Belongs to the UPF0246 family
PPPDDIND_01903 3.4e-169 XK27_01785 S cog cog1284
PPPDDIND_01904 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PPPDDIND_01906 1.2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
PPPDDIND_01907 4.3e-130 metE 2.1.1.14 E Methionine synthase
PPPDDIND_01908 1.4e-36 metE 2.1.1.14 E Methionine synthase
PPPDDIND_01909 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PPPDDIND_01910 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PPPDDIND_01913 4.8e-51 yegS 2.7.1.107 I lipid kinase activity
PPPDDIND_01914 8.5e-97 S Hydrophobic domain protein
PPPDDIND_01916 7.4e-28 S Membrane
PPPDDIND_01917 1.4e-101
PPPDDIND_01918 1.8e-23 S Small integral membrane protein
PPPDDIND_01919 1.1e-85 M Protein conserved in bacteria
PPPDDIND_01920 2.8e-12 K CsbD-like
PPPDDIND_01921 2.8e-102 nudL L hydrolase
PPPDDIND_01922 3.4e-13 nudL L hydrolase
PPPDDIND_01923 4e-19 K negative regulation of transcription, DNA-templated
PPPDDIND_01924 4.4e-24 K negative regulation of transcription, DNA-templated
PPPDDIND_01926 8e-109 S Putative adhesin
PPPDDIND_01927 5.6e-160 XK27_06930 V domain protein
PPPDDIND_01928 6.4e-96 XK27_06935 K transcriptional regulator
PPPDDIND_01929 4.8e-55 ypaA S membrane
PPPDDIND_01930 2.7e-08
PPPDDIND_01931 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PPPDDIND_01932 8.2e-48 veg S Biofilm formation stimulator VEG
PPPDDIND_01933 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PPPDDIND_01934 6.7e-70 rplI J binds to the 23S rRNA
PPPDDIND_01935 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PPPDDIND_01936 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PPPDDIND_01937 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PPPDDIND_01938 0.0 S Bacterial membrane protein, YfhO
PPPDDIND_01939 2e-93 isaA GH23 M Immunodominant staphylococcal antigen A
PPPDDIND_01940 3.1e-93 lytE M LysM domain protein
PPPDDIND_01941 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPDDIND_01942 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPDDIND_01943 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPDDIND_01944 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPPDDIND_01945 1.7e-138 ymfM S sequence-specific DNA binding
PPPDDIND_01946 1.2e-241 ymfH S Peptidase M16
PPPDDIND_01947 4.8e-235 ymfF S Peptidase M16
PPPDDIND_01948 1.6e-45 yaaA S S4 domain protein YaaA
PPPDDIND_01949 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PPPDDIND_01950 2.1e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PPPDDIND_01951 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PPPDDIND_01952 4.2e-153 yvjA S membrane
PPPDDIND_01953 6.7e-306 ybiT S abc transporter atp-binding protein
PPPDDIND_01954 0.0 XK27_10405 S Bacterial membrane protein YfhO
PPPDDIND_01958 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
PPPDDIND_01959 8.6e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PPPDDIND_01960 4.3e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PPPDDIND_01961 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)