ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDLFAENC_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDLFAENC_00002 4.8e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDLFAENC_00003 1.1e-29 yyzM S Protein conserved in bacteria
HDLFAENC_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDLFAENC_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDLFAENC_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDLFAENC_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HDLFAENC_00008 2.7e-61 divIC D Septum formation initiator
HDLFAENC_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HDLFAENC_00011 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDLFAENC_00012 1e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDLFAENC_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDLFAENC_00014 1.6e-134 L Transposase
HDLFAENC_00015 9.4e-46 L transposase activity
HDLFAENC_00016 2.5e-22 L Transposase
HDLFAENC_00017 1e-54 L transposition
HDLFAENC_00018 2.9e-87 L Integrase core domain protein
HDLFAENC_00031 5.3e-11
HDLFAENC_00037 1.7e-140 mreC M Involved in formation and maintenance of cell shape
HDLFAENC_00038 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HDLFAENC_00039 7.8e-93 usp 3.5.1.28 CBM50 S CHAP domain
HDLFAENC_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLFAENC_00041 2.5e-26
HDLFAENC_00042 5.9e-219 araT 2.6.1.1 E Aminotransferase
HDLFAENC_00043 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
HDLFAENC_00044 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDLFAENC_00045 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLFAENC_00046 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDLFAENC_00047 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLFAENC_00048 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDLFAENC_00049 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDLFAENC_00050 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDLFAENC_00051 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDLFAENC_00052 1.2e-79 L transposase activity
HDLFAENC_00053 6e-52 L transposition
HDLFAENC_00054 1.2e-160 S CHAP domain
HDLFAENC_00055 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
HDLFAENC_00056 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDLFAENC_00057 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDLFAENC_00058 9.2e-141 1.1.1.169 H Ketopantoate reductase
HDLFAENC_00059 3.4e-24
HDLFAENC_00060 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDLFAENC_00061 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HDLFAENC_00062 8.2e-70 argR K Regulates arginine biosynthesis genes
HDLFAENC_00063 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HDLFAENC_00064 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDLFAENC_00065 1.4e-34 S Protein of unknown function (DUF3021)
HDLFAENC_00066 3.2e-62 KT phosphorelay signal transduction system
HDLFAENC_00068 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDLFAENC_00070 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDLFAENC_00071 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HDLFAENC_00072 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
HDLFAENC_00073 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDLFAENC_00074 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HDLFAENC_00080 2.6e-10
HDLFAENC_00083 1.9e-07
HDLFAENC_00088 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLFAENC_00089 3.6e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HDLFAENC_00090 5.5e-36 XK27_02060 S Transglycosylase associated protein
HDLFAENC_00091 1.8e-26 badR K DNA-binding transcription factor activity
HDLFAENC_00092 3.9e-96 S reductase
HDLFAENC_00093 3.8e-87 L Integrase core domain protein
HDLFAENC_00094 1.9e-40 L transposition
HDLFAENC_00095 4.2e-77 yocD 3.4.17.13 V carboxypeptidase activity
HDLFAENC_00096 2.7e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HDLFAENC_00098 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HDLFAENC_00099 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDLFAENC_00100 1.1e-83 S Putative small multi-drug export protein
HDLFAENC_00101 6.2e-76 ctsR K Belongs to the CtsR family
HDLFAENC_00102 0.0 clpC O Belongs to the ClpA ClpB family
HDLFAENC_00103 9.1e-150 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_00104 5.5e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_00105 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_00106 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDLFAENC_00107 2.9e-142 S SseB protein N-terminal domain
HDLFAENC_00108 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HDLFAENC_00109 6.6e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDLFAENC_00110 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDLFAENC_00113 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLFAENC_00114 7.8e-85 yacP S RNA-binding protein containing a PIN domain
HDLFAENC_00115 3.7e-154 degV S DegV family
HDLFAENC_00116 4.7e-32 K helix-turn-helix
HDLFAENC_00117 1e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLFAENC_00118 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDLFAENC_00119 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HDLFAENC_00120 3.3e-250 L Transposase
HDLFAENC_00121 1.1e-145 L Transposase
HDLFAENC_00122 2.3e-181 EGP Major facilitator Superfamily
HDLFAENC_00123 6.8e-63 3.6.4.12 K Divergent AAA domain protein
HDLFAENC_00124 1.1e-18 3.6.4.12 K Divergent AAA domain protein
HDLFAENC_00125 4.5e-222 int L Belongs to the 'phage' integrase family
HDLFAENC_00126 2.9e-36 S Helix-turn-helix domain
HDLFAENC_00127 2e-186
HDLFAENC_00129 4e-76 isp2 S pathogenesis
HDLFAENC_00130 1.3e-90 tnp L Transposase
HDLFAENC_00131 3.1e-223 capA M Bacterial capsule synthesis protein
HDLFAENC_00132 3.6e-39 gcvR T UPF0237 protein
HDLFAENC_00133 1.7e-243 XK27_08635 S UPF0210 protein
HDLFAENC_00134 4.6e-134 ais G Phosphoglycerate mutase
HDLFAENC_00135 9.7e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HDLFAENC_00136 2.5e-101 acmA 3.2.1.17 NU amidase activity
HDLFAENC_00137 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDLFAENC_00138 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDLFAENC_00139 4.9e-297 dnaK O Heat shock 70 kDa protein
HDLFAENC_00140 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDLFAENC_00141 1.7e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDLFAENC_00142 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HDLFAENC_00143 5.9e-61 hmpT S membrane
HDLFAENC_00156 3.1e-159 amiA E ABC transporter, substrate-binding protein, family 5
HDLFAENC_00157 8e-143 amiA E ABC transporter, substrate-binding protein, family 5
HDLFAENC_00158 2.5e-169 L Transposase
HDLFAENC_00159 9.9e-19 S Domain of unknown function (DUF4649)
HDLFAENC_00160 3.3e-55 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDLFAENC_00161 4.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDLFAENC_00162 6.1e-85
HDLFAENC_00163 1.6e-77 sigH K DNA-templated transcription, initiation
HDLFAENC_00164 1.3e-148 ykuT M mechanosensitive ion channel
HDLFAENC_00165 4.9e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDLFAENC_00166 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDLFAENC_00167 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDLFAENC_00168 2.9e-84 XK27_03960 S Protein of unknown function (DUF3013)
HDLFAENC_00169 7e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HDLFAENC_00170 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
HDLFAENC_00171 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDLFAENC_00172 1.1e-45 F nucleotide catabolic process
HDLFAENC_00173 2.1e-138 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDLFAENC_00174 5e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDLFAENC_00175 2e-52 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDLFAENC_00176 1.7e-81 nrdI F Belongs to the NrdI family
HDLFAENC_00177 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDLFAENC_00178 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDLFAENC_00179 6.8e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLFAENC_00180 4e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLFAENC_00181 6e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLFAENC_00182 1.5e-40 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLFAENC_00183 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDLFAENC_00184 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDLFAENC_00185 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HDLFAENC_00186 7.9e-200 yhjX P Major Facilitator
HDLFAENC_00187 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDLFAENC_00188 1.1e-93 V VanZ like family
HDLFAENC_00191 1e-123 glnQ E abc transporter atp-binding protein
HDLFAENC_00192 2e-275 glnP P ABC transporter
HDLFAENC_00193 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDLFAENC_00194 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDLFAENC_00195 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
HDLFAENC_00196 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HDLFAENC_00197 1.4e-234 sufD O assembly protein SufD
HDLFAENC_00198 6.5e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDLFAENC_00199 1.9e-74 nifU C SUF system FeS assembly protein, NifU family
HDLFAENC_00200 2.2e-273 sufB O assembly protein SufB
HDLFAENC_00201 3.3e-19 oppA E ABC transporter substrate-binding protein
HDLFAENC_00202 5.9e-91 oppA E ABC transporter substrate-binding protein
HDLFAENC_00203 4.5e-39 oppA E ABC transporter substrate-binding protein
HDLFAENC_00204 1.9e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLFAENC_00205 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLFAENC_00206 7.8e-44 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLFAENC_00207 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLFAENC_00208 3e-27 oppD P Belongs to the ABC transporter superfamily
HDLFAENC_00209 8.6e-20 oppD P Belongs to the ABC transporter superfamily
HDLFAENC_00210 1.4e-66 oppD P Belongs to the ABC transporter superfamily
HDLFAENC_00211 1.1e-164 oppF P Belongs to the ABC transporter superfamily
HDLFAENC_00214 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDLFAENC_00215 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLFAENC_00216 6e-128 K sequence-specific DNA binding
HDLFAENC_00217 1.1e-149 KLT serine threonine protein kinase
HDLFAENC_00218 1.4e-300 KLT serine threonine protein kinase
HDLFAENC_00219 4.2e-223 EGP Major facilitator Superfamily
HDLFAENC_00220 3.1e-72 adcR K transcriptional
HDLFAENC_00221 1.3e-136 adcC P ABC transporter, ATP-binding protein
HDLFAENC_00222 3.9e-129 adcB P ABC transporter (Permease
HDLFAENC_00223 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HDLFAENC_00224 4.3e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HDLFAENC_00225 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
HDLFAENC_00226 1.4e-244 ptsG 2.7.1.199, 2.7.1.208 G pts system
HDLFAENC_00227 1.5e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HDLFAENC_00228 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
HDLFAENC_00229 1.9e-127 yeeN K transcriptional regulatory protein
HDLFAENC_00230 1.3e-49 yajC U protein transport
HDLFAENC_00231 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDLFAENC_00232 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HDLFAENC_00233 4.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDLFAENC_00234 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDLFAENC_00235 0.0 WQ51_06230 S ABC transporter substrate binding protein
HDLFAENC_00236 5.2e-142 cmpC S abc transporter atp-binding protein
HDLFAENC_00237 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDLFAENC_00238 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDLFAENC_00239 1.4e-75 L transposase activity
HDLFAENC_00240 2.7e-90 L Transposase and inactivated derivatives
HDLFAENC_00243 9.4e-44
HDLFAENC_00244 2.7e-28 J TM2 domain
HDLFAENC_00245 6.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDLFAENC_00246 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLFAENC_00247 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
HDLFAENC_00248 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HDLFAENC_00249 7.3e-83 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HDLFAENC_00250 4.6e-55 cof Q phosphatase activity
HDLFAENC_00251 2.1e-35 cof Q phosphatase activity
HDLFAENC_00252 1.4e-136 glcR K transcriptional regulator (DeoR family)
HDLFAENC_00253 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDLFAENC_00254 3.8e-40 K transcriptional
HDLFAENC_00255 5.3e-87 S thiolester hydrolase activity
HDLFAENC_00256 2.2e-142 S COG1073 Hydrolases of the alpha beta superfamily
HDLFAENC_00257 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLFAENC_00258 6.2e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDLFAENC_00259 3.2e-77 yhaI L Membrane
HDLFAENC_00260 6e-260 pepC 3.4.22.40 E aminopeptidase
HDLFAENC_00261 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLFAENC_00262 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDLFAENC_00263 3.1e-95 ypsA S Belongs to the UPF0398 family
HDLFAENC_00264 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDLFAENC_00265 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDLFAENC_00266 1.1e-299 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HDLFAENC_00267 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HDLFAENC_00268 9.6e-23
HDLFAENC_00269 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDLFAENC_00270 9.2e-83 XK27_09675 K -acetyltransferase
HDLFAENC_00271 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDLFAENC_00272 4.5e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLFAENC_00274 1.2e-51 L Integrase core domain protein
HDLFAENC_00275 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLFAENC_00276 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDLFAENC_00277 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLFAENC_00278 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HDLFAENC_00279 8.8e-98 ybhL S Belongs to the BI1 family
HDLFAENC_00282 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDLFAENC_00283 9.6e-92 K transcriptional regulator
HDLFAENC_00284 7.6e-36 yneF S UPF0154 protein
HDLFAENC_00285 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDLFAENC_00286 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDLFAENC_00287 1e-98 XK27_09740 S Phosphoesterase
HDLFAENC_00288 1.6e-85 ykuL S CBS domain
HDLFAENC_00289 4.4e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HDLFAENC_00290 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDLFAENC_00291 4.3e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDLFAENC_00292 1.3e-139 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLFAENC_00293 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDLFAENC_00294 1.2e-258 trkH P Cation transport protein
HDLFAENC_00295 1.8e-248 trkA P Potassium transporter peripheral membrane component
HDLFAENC_00296 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDLFAENC_00297 5.1e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDLFAENC_00298 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HDLFAENC_00299 3.3e-161 K sequence-specific DNA binding
HDLFAENC_00300 1.9e-33 V protein secretion by the type I secretion system
HDLFAENC_00301 5.1e-103 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLFAENC_00302 7.7e-33 V protein secretion by the type I secretion system
HDLFAENC_00303 1.6e-62 comA V protein secretion by the type I secretion system
HDLFAENC_00304 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLFAENC_00305 3.7e-22 yhaI L Membrane
HDLFAENC_00306 1.9e-132 S Domain of unknown function (DUF4173)
HDLFAENC_00307 6.8e-95 ureI S AmiS/UreI family transporter
HDLFAENC_00308 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HDLFAENC_00309 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HDLFAENC_00310 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HDLFAENC_00311 2.5e-77 ureE O enzyme active site formation
HDLFAENC_00312 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HDLFAENC_00313 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HDLFAENC_00314 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HDLFAENC_00315 1.9e-175 cbiM P PDGLE domain
HDLFAENC_00316 1.7e-137 P cobalt transport protein
HDLFAENC_00317 3.1e-130 cbiO P ABC transporter
HDLFAENC_00318 1.3e-138 ET amino acid transport
HDLFAENC_00319 1.1e-164 metQ M Belongs to the NlpA lipoprotein family
HDLFAENC_00320 2.1e-85 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HDLFAENC_00321 1.1e-92 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HDLFAENC_00322 1.3e-17 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HDLFAENC_00323 1.6e-20 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HDLFAENC_00324 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLFAENC_00325 3e-98 metI P ABC transporter (Permease
HDLFAENC_00326 7.9e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HDLFAENC_00327 5.4e-78 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HDLFAENC_00328 2e-51 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HDLFAENC_00329 1.2e-26 P Psort location CytoplasmicMembrane, score
HDLFAENC_00330 2.5e-34 S UPF0397 protein
HDLFAENC_00331 0.0 ykoD P abc transporter atp-binding protein
HDLFAENC_00332 2.2e-148 cbiQ P cobalt transport
HDLFAENC_00333 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDLFAENC_00334 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
HDLFAENC_00335 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HDLFAENC_00336 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
HDLFAENC_00337 4e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HDLFAENC_00338 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
HDLFAENC_00339 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLFAENC_00340 4.8e-282 T PhoQ Sensor
HDLFAENC_00341 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDLFAENC_00342 5e-218 dnaB L Replication initiation and membrane attachment
HDLFAENC_00343 4e-167 dnaI L Primosomal protein DnaI
HDLFAENC_00344 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDLFAENC_00346 1.6e-12 yrdC 3.5.1.19 Q isochorismatase
HDLFAENC_00347 2.6e-26 yrdC 3.5.1.19 Q isochorismatase
HDLFAENC_00348 1.8e-27 L Transposase and inactivated derivatives
HDLFAENC_00349 9.3e-51 L transposition
HDLFAENC_00350 2.5e-22 L Transposase
HDLFAENC_00351 8.6e-46 L transposase activity
HDLFAENC_00352 1.3e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDLFAENC_00353 6.5e-63 manO S protein conserved in bacteria
HDLFAENC_00354 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
HDLFAENC_00355 7.8e-117 manM G pts system
HDLFAENC_00356 1.1e-181 manL 2.7.1.191 G pts system
HDLFAENC_00357 5.8e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HDLFAENC_00358 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HDLFAENC_00359 1.5e-248 pbuO S permease
HDLFAENC_00360 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HDLFAENC_00361 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HDLFAENC_00362 1e-218 brpA K Transcriptional
HDLFAENC_00363 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HDLFAENC_00364 4.1e-212 nusA K Participates in both transcription termination and antitermination
HDLFAENC_00365 8.8e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HDLFAENC_00366 1.4e-41 ylxQ J ribosomal protein
HDLFAENC_00367 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDLFAENC_00368 2.3e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDLFAENC_00369 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HDLFAENC_00370 9.8e-37 yvdD 3.2.2.10 L Belongs to the LOG family
HDLFAENC_00371 4.8e-235 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HDLFAENC_00372 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDLFAENC_00373 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HDLFAENC_00374 5.7e-86 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HDLFAENC_00375 7.9e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HDLFAENC_00376 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HDLFAENC_00377 4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HDLFAENC_00378 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDLFAENC_00379 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDLFAENC_00380 9.8e-74 ylbF S Belongs to the UPF0342 family
HDLFAENC_00381 9.3e-46 ylbG S UPF0298 protein
HDLFAENC_00382 5.3e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HDLFAENC_00383 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HDLFAENC_00384 1.8e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HDLFAENC_00385 8.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HDLFAENC_00386 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HDLFAENC_00387 2.5e-63 acuB S CBS domain
HDLFAENC_00388 7.7e-13 acuB S IMP dehydrogenase activity
HDLFAENC_00389 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDLFAENC_00390 1.4e-110 yvyE 3.4.13.9 S YigZ family
HDLFAENC_00391 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HDLFAENC_00392 3.4e-123 comFC S Competence protein
HDLFAENC_00393 2.3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDLFAENC_00401 6e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDLFAENC_00402 6.4e-108 S Domain of unknown function (DUF1803)
HDLFAENC_00403 7.8e-102 ygaC J Belongs to the UPF0374 family
HDLFAENC_00404 2.8e-132 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDLFAENC_00405 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLFAENC_00406 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
HDLFAENC_00407 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDLFAENC_00408 5.6e-115 S Haloacid dehalogenase-like hydrolase
HDLFAENC_00409 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HDLFAENC_00410 1.4e-72 marR K Transcriptional regulator, MarR family
HDLFAENC_00411 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLFAENC_00412 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLFAENC_00413 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HDLFAENC_00414 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDLFAENC_00415 1.3e-126 IQ reductase
HDLFAENC_00416 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDLFAENC_00417 2.2e-55 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDLFAENC_00418 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDLFAENC_00419 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HDLFAENC_00420 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDLFAENC_00421 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDLFAENC_00422 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDLFAENC_00423 8.2e-213 sip L Belongs to the 'phage' integrase family
HDLFAENC_00424 1e-18 xre K Cro/C1-type HTH DNA-binding domain
HDLFAENC_00425 1e-19 K Cro/C1-type HTH DNA-binding domain
HDLFAENC_00429 1.1e-12
HDLFAENC_00430 4.1e-22
HDLFAENC_00431 8.6e-143 KL Phage plasmid primase P4 family
HDLFAENC_00432 5.1e-284 S DNA primase
HDLFAENC_00434 6.1e-08
HDLFAENC_00436 8e-74 L Replication protein
HDLFAENC_00438 4.3e-171 aaxC E Arginine ornithine antiporter
HDLFAENC_00439 3.1e-122 4.1.1.22 H Histidine carboxylase PI chain
HDLFAENC_00441 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLFAENC_00442 2.1e-296 hsdM 2.1.1.72 V HsdM N-terminal domain
HDLFAENC_00443 3e-117 3.1.21.3 V type I restriction modification DNA specificity domain protein
HDLFAENC_00445 1.5e-204 rny D Endoribonuclease that initiates mRNA decay
HDLFAENC_00446 1.4e-84 L Transposase
HDLFAENC_00447 2.1e-113 fruR K transcriptional
HDLFAENC_00448 2.1e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDLFAENC_00449 2.1e-52 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
HDLFAENC_00450 7.8e-22 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
HDLFAENC_00451 3.9e-141 fruA 2.7.1.202 G phosphotransferase system
HDLFAENC_00452 7.3e-37 fruA 2.7.1.202 G phosphotransferase system
HDLFAENC_00453 4.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDLFAENC_00454 9e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDLFAENC_00456 2.3e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HDLFAENC_00457 2.7e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLFAENC_00458 3.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HDLFAENC_00459 1.1e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HDLFAENC_00460 1.1e-38 2.3.1.128 K acetyltransferase
HDLFAENC_00461 6.4e-29 2.3.1.128 K acetyltransferase
HDLFAENC_00462 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDLFAENC_00463 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDLFAENC_00464 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLFAENC_00465 2.6e-64 WQ51_03320 S cog cog4835
HDLFAENC_00466 3.1e-92 XK27_08360 S EDD domain protein, DegV family
HDLFAENC_00467 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDLFAENC_00468 5.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDLFAENC_00469 0.0 yfmR S abc transporter atp-binding protein
HDLFAENC_00470 1.6e-24 U response to pH
HDLFAENC_00471 1.5e-138 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HDLFAENC_00472 1.3e-78 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HDLFAENC_00473 2.4e-86 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HDLFAENC_00474 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDLFAENC_00475 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDLFAENC_00476 9.4e-77 K DNA-binding transcription factor activity
HDLFAENC_00477 0.0 lmrA1 V abc transporter atp-binding protein
HDLFAENC_00478 0.0 lmrA2 V abc transporter atp-binding protein
HDLFAENC_00479 1.2e-36 K Acetyltransferase (GNAT) family
HDLFAENC_00480 2.6e-121 sptS 2.7.13.3 T Histidine kinase
HDLFAENC_00481 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDLFAENC_00482 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDLFAENC_00483 1.7e-159 cvfB S Protein conserved in bacteria
HDLFAENC_00484 7.4e-35 yozE S Belongs to the UPF0346 family
HDLFAENC_00485 2.5e-99 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
HDLFAENC_00486 7.5e-225 L Transposase
HDLFAENC_00487 3.6e-62 rlpA M LysM domain protein
HDLFAENC_00488 8e-191 phoH T phosphate starvation-inducible protein PhoH
HDLFAENC_00490 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDLFAENC_00491 3.4e-166 K transcriptional regulator (lysR family)
HDLFAENC_00492 2.2e-184 coiA 3.6.4.12 S Competence protein
HDLFAENC_00493 0.0 pepF E oligoendopeptidase F
HDLFAENC_00494 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HDLFAENC_00495 3.9e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HDLFAENC_00496 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDLFAENC_00497 3.5e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLFAENC_00498 5e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLFAENC_00499 6e-64 3.4.17.14, 3.5.1.28 NU amidase activity
HDLFAENC_00500 4.6e-129 3.4.17.14, 3.5.1.28 NU amidase activity
HDLFAENC_00501 1.5e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDLFAENC_00502 1.2e-227 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HDLFAENC_00503 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDLFAENC_00504 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDLFAENC_00505 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HDLFAENC_00506 4.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HDLFAENC_00507 2.1e-140 yxkH G deacetylase
HDLFAENC_00508 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HDLFAENC_00509 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDLFAENC_00510 9.4e-153 rarD S Transporter
HDLFAENC_00511 1.3e-15 T peptidase
HDLFAENC_00512 8.9e-14 coiA 3.6.4.12 S Competence protein
HDLFAENC_00513 2.5e-41 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLFAENC_00514 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDLFAENC_00515 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLFAENC_00516 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HDLFAENC_00517 3.3e-78 atpF C ATP synthase F(0) sector subunit b
HDLFAENC_00518 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLFAENC_00519 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDLFAENC_00520 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDLFAENC_00521 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDLFAENC_00522 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDLFAENC_00523 3.8e-158 L Transposase
HDLFAENC_00524 8.1e-230 ftsW D Belongs to the SEDS family
HDLFAENC_00525 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDLFAENC_00526 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDLFAENC_00527 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDLFAENC_00528 6.4e-162 holB 2.7.7.7 L dna polymerase iii
HDLFAENC_00529 1.2e-135 yaaT S stage 0 sporulation protein
HDLFAENC_00530 9.5e-55 yabA L Involved in initiation control of chromosome replication
HDLFAENC_00531 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDLFAENC_00532 5.8e-233 amt P Ammonium Transporter
HDLFAENC_00533 1.1e-53 glnB K Belongs to the P(II) protein family
HDLFAENC_00534 3.2e-105 mur1 NU mannosyl-glycoprotein
HDLFAENC_00535 5e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HDLFAENC_00536 3.7e-113 nptA P COG1283 Na phosphate symporter
HDLFAENC_00537 2.3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDLFAENC_00538 1.6e-54
HDLFAENC_00539 4.4e-26
HDLFAENC_00540 7.1e-62
HDLFAENC_00541 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDLFAENC_00542 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDLFAENC_00543 4.5e-39 ynzC S UPF0291 protein
HDLFAENC_00544 2.5e-253 cycA E permease
HDLFAENC_00545 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
HDLFAENC_00546 2.9e-21 pts33BCA G pts system
HDLFAENC_00547 5.8e-71 pts33BCA G pts system
HDLFAENC_00548 7.6e-95 pts33BCA G pts system
HDLFAENC_00549 1.3e-76 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
HDLFAENC_00550 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLFAENC_00555 1.4e-167 fhuR K transcriptional regulator (lysR family)
HDLFAENC_00556 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDLFAENC_00557 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDLFAENC_00558 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDLFAENC_00559 1.1e-226 pyrP F uracil Permease
HDLFAENC_00560 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDLFAENC_00561 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HDLFAENC_00562 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HDLFAENC_00563 4.9e-134 J Putative SAM-dependent methyltransferase
HDLFAENC_00564 9.6e-18 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLFAENC_00565 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLFAENC_00566 8.1e-66 V permease protein
HDLFAENC_00567 8.2e-61 V efflux transmembrane transporter activity
HDLFAENC_00568 8.2e-28 ytrF V efflux transmembrane transporter activity
HDLFAENC_00569 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDLFAENC_00570 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDLFAENC_00572 0.0 mdlB V abc transporter atp-binding protein
HDLFAENC_00573 0.0 lmrA V abc transporter atp-binding protein
HDLFAENC_00574 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDLFAENC_00575 6.6e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDLFAENC_00576 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HDLFAENC_00577 1.9e-132 rr02 KT response regulator
HDLFAENC_00578 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDLFAENC_00579 2.8e-168 V ABC transporter
HDLFAENC_00580 5.4e-122 sagI S ABC-2 type transporter
HDLFAENC_00581 6.9e-197 yceA S Belongs to the UPF0176 family
HDLFAENC_00582 1.9e-29 XK27_00085 K Transcriptional
HDLFAENC_00583 1.9e-22
HDLFAENC_00584 1.1e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
HDLFAENC_00585 2.5e-113 S VIT family
HDLFAENC_00586 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLFAENC_00587 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDLFAENC_00588 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HDLFAENC_00589 1.5e-45 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HDLFAENC_00590 3e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDLFAENC_00591 2e-94 GBS0088 J protein conserved in bacteria
HDLFAENC_00592 4.8e-141 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HDLFAENC_00593 2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDLFAENC_00594 1.9e-178 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HDLFAENC_00595 1.2e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDLFAENC_00596 1.6e-252 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDLFAENC_00597 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HDLFAENC_00598 2.5e-21
HDLFAENC_00599 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDLFAENC_00601 3.5e-07 U protein secretion
HDLFAENC_00602 1.7e-52 U protein secretion
HDLFAENC_00603 1.1e-11 U protein secretion
HDLFAENC_00604 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HDLFAENC_00605 5.2e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HDLFAENC_00606 4.9e-21 XK27_13030
HDLFAENC_00607 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDLFAENC_00608 7.4e-172 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDLFAENC_00609 5.2e-164 S Protein of unknown function (DUF3114)
HDLFAENC_00610 1.2e-22 S Protein of unknown function (DUF3114)
HDLFAENC_00611 5.8e-118 yqfA K protein, Hemolysin III
HDLFAENC_00612 1e-25 K hmm pf08876
HDLFAENC_00613 2.2e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDLFAENC_00614 1.7e-218 mvaS 2.3.3.10 I synthase
HDLFAENC_00615 1.5e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDLFAENC_00616 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDLFAENC_00617 9.7e-22
HDLFAENC_00618 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDLFAENC_00619 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HDLFAENC_00620 4.4e-250 mmuP E amino acid
HDLFAENC_00621 1e-176 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HDLFAENC_00622 1.4e-29 S Domain of unknown function (DUF1912)
HDLFAENC_00623 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
HDLFAENC_00624 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDLFAENC_00625 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLFAENC_00626 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLFAENC_00627 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HDLFAENC_00628 4.8e-16 S Protein of unknown function (DUF2969)
HDLFAENC_00631 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
HDLFAENC_00634 2.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
HDLFAENC_00635 1.1e-30 S Domain of Unknown Function with PDB structure (DUF3862)
HDLFAENC_00636 3.7e-70 M Pfam SNARE associated Golgi protein
HDLFAENC_00637 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
HDLFAENC_00638 7e-26 2.7.7.15 S inositol 2-dehydrogenase activity
HDLFAENC_00639 1.5e-49 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
HDLFAENC_00640 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
HDLFAENC_00641 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HDLFAENC_00642 0.0 clpE O Belongs to the ClpA ClpB family
HDLFAENC_00643 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDLFAENC_00644 1.3e-34 ykuJ S protein conserved in bacteria
HDLFAENC_00645 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HDLFAENC_00646 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_00647 1.1e-78 feoA P FeoA domain protein
HDLFAENC_00648 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HDLFAENC_00649 6.6e-08
HDLFAENC_00650 1.5e-35 yugF I carboxylic ester hydrolase activity
HDLFAENC_00651 1.3e-22 I Alpha/beta hydrolase family
HDLFAENC_00652 6.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDLFAENC_00653 7e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDLFAENC_00654 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HDLFAENC_00655 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDLFAENC_00656 2.4e-43 licT K transcriptional antiterminator
HDLFAENC_00657 5e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDLFAENC_00658 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDLFAENC_00659 3.7e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDLFAENC_00660 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDLFAENC_00661 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDLFAENC_00662 2.9e-221 mdtG EGP Major facilitator Superfamily
HDLFAENC_00663 2e-33 secG U Preprotein translocase subunit SecG
HDLFAENC_00664 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDLFAENC_00665 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDLFAENC_00666 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLFAENC_00667 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HDLFAENC_00668 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HDLFAENC_00669 4.4e-183 ccpA K Catabolite control protein A
HDLFAENC_00670 1.5e-26 yyaQ S YjbR
HDLFAENC_00671 1.5e-143 yyaQ S YjbR
HDLFAENC_00672 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDLFAENC_00673 4.5e-74 yueI S Protein of unknown function (DUF1694)
HDLFAENC_00674 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDLFAENC_00676 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDLFAENC_00677 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
HDLFAENC_00678 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDLFAENC_00679 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLFAENC_00680 3.8e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDLFAENC_00681 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDLFAENC_00682 2.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HDLFAENC_00683 3.2e-53 yheA S Belongs to the UPF0342 family
HDLFAENC_00684 7.9e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HDLFAENC_00685 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDLFAENC_00686 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDLFAENC_00687 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
HDLFAENC_00688 6.2e-247 msrR K Transcriptional regulator
HDLFAENC_00689 1e-112 ydiA P C4-dicarboxylate transporter malic acid transport protein
HDLFAENC_00690 1.6e-202 I acyl-CoA dehydrogenase
HDLFAENC_00691 2.7e-97 mip S hydroperoxide reductase activity
HDLFAENC_00692 9.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLFAENC_00693 3.6e-92
HDLFAENC_00694 1.5e-18 K Cro/C1-type HTH DNA-binding domain
HDLFAENC_00695 1.9e-51 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HDLFAENC_00696 2.6e-34 estA E GDSL-like Lipase/Acylhydrolase
HDLFAENC_00697 2.8e-95
HDLFAENC_00698 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLFAENC_00699 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLFAENC_00700 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLFAENC_00701 1.1e-189 S CRISPR-associated protein Csn2 subfamily St
HDLFAENC_00702 1.2e-146 ycgQ S TIGR03943 family
HDLFAENC_00703 7.1e-156 XK27_03015 S permease
HDLFAENC_00705 0.0 yhgF K Transcriptional accessory protein
HDLFAENC_00706 4.2e-85 ydcK S Belongs to the SprT family
HDLFAENC_00707 5.5e-40 pspC KT PspC domain
HDLFAENC_00708 3.1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDLFAENC_00709 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDLFAENC_00711 6.1e-68 ytxH S General stress protein
HDLFAENC_00713 3e-178 yegQ O Peptidase U32
HDLFAENC_00714 3.4e-252 yegQ O Peptidase U32
HDLFAENC_00715 5.5e-87 bioY S biotin synthase
HDLFAENC_00717 2.6e-32 XK27_12190 S protein conserved in bacteria
HDLFAENC_00718 9.6e-234 mntH P H( )-stimulated, divalent metal cation uptake system
HDLFAENC_00719 7.6e-09
HDLFAENC_00720 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
HDLFAENC_00721 0.0 L helicase
HDLFAENC_00722 5.4e-281 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDLFAENC_00723 1.9e-15 M LysM domain
HDLFAENC_00724 2.6e-113 M LysM domain
HDLFAENC_00725 2.2e-08
HDLFAENC_00726 1.2e-171 S hydrolase
HDLFAENC_00727 1.1e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HDLFAENC_00728 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDLFAENC_00729 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HDLFAENC_00730 2.7e-27 P Hemerythrin HHE cation binding domain protein
HDLFAENC_00731 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDLFAENC_00732 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
HDLFAENC_00733 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
HDLFAENC_00734 4.7e-23 MA20_36090 S Protein of unknown function (DUF2974)
HDLFAENC_00735 1e-81 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLFAENC_00736 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HDLFAENC_00737 4.1e-271 hsdM 2.1.1.72 V N-6 DNA Methylase
HDLFAENC_00738 2e-139 3.1.21.3 V type I restriction modification DNA specificity domain
HDLFAENC_00740 9.1e-44
HDLFAENC_00741 8.9e-38
HDLFAENC_00742 4.9e-174 spd F DNA RNA non-specific endonuclease
HDLFAENC_00743 1.5e-92 lemA S LemA family
HDLFAENC_00744 6.4e-133 htpX O Belongs to the peptidase M48B family
HDLFAENC_00745 4.2e-75 S Psort location CytoplasmicMembrane, score
HDLFAENC_00746 6.2e-56 S Domain of unknown function (DUF4430)
HDLFAENC_00747 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HDLFAENC_00748 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HDLFAENC_00749 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HDLFAENC_00750 2.5e-197 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HDLFAENC_00751 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDLFAENC_00752 1.6e-91 dps P Belongs to the Dps family
HDLFAENC_00753 3.1e-80 perR P Belongs to the Fur family
HDLFAENC_00754 1.9e-27 yqgQ S protein conserved in bacteria
HDLFAENC_00755 2.9e-179 glk 2.7.1.2 G Glucokinase
HDLFAENC_00756 0.0 typA T GTP-binding protein TypA
HDLFAENC_00758 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDLFAENC_00759 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDLFAENC_00760 7.7e-176 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDLFAENC_00761 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDLFAENC_00762 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDLFAENC_00763 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDLFAENC_00764 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDLFAENC_00765 2.6e-34 yggT D integral membrane protein
HDLFAENC_00766 5.2e-142 ylmH T S4 RNA-binding domain
HDLFAENC_00767 7.9e-136 divIVA D Cell division protein DivIVA
HDLFAENC_00768 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDLFAENC_00769 3.8e-16
HDLFAENC_00770 1.3e-10
HDLFAENC_00771 1e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
HDLFAENC_00772 2e-45 rpmE2 J 50S ribosomal protein L31
HDLFAENC_00773 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLFAENC_00774 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HDLFAENC_00775 5.8e-154 gst O Glutathione S-transferase
HDLFAENC_00776 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDLFAENC_00777 7.1e-112 tdk 2.7.1.21 F thymidine kinase
HDLFAENC_00778 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDLFAENC_00779 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDLFAENC_00780 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDLFAENC_00781 1.4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDLFAENC_00782 1.8e-176 ndpA S 37-kD nucleoid-associated bacterial protein
HDLFAENC_00783 6.5e-99 pvaA M lytic transglycosylase activity
HDLFAENC_00784 0.0 yfiB1 V abc transporter atp-binding protein
HDLFAENC_00785 0.0 XK27_10035 V abc transporter atp-binding protein
HDLFAENC_00786 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
HDLFAENC_00787 3.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLFAENC_00788 4.6e-238 dltB M Membrane protein involved in D-alanine export
HDLFAENC_00789 3.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLFAENC_00790 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDLFAENC_00791 2.4e-33 L Integrase core domain protein
HDLFAENC_00792 3.6e-31 L Integrase core domain protein
HDLFAENC_00793 6.5e-54 L transposition
HDLFAENC_00794 7.7e-19 L transposase activity
HDLFAENC_00795 0.0 3.6.3.8 P cation transport ATPase
HDLFAENC_00796 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HDLFAENC_00798 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDLFAENC_00799 6.2e-165 metF 1.5.1.20 C reductase
HDLFAENC_00800 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HDLFAENC_00801 1.2e-92 panT S ECF transporter, substrate-specific component
HDLFAENC_00802 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDLFAENC_00803 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HDLFAENC_00804 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDLFAENC_00805 2.3e-87 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLFAENC_00806 4.3e-41 T PhoQ Sensor
HDLFAENC_00807 1.7e-43 T PhoQ Sensor
HDLFAENC_00808 8.3e-78 T PhoQ Sensor
HDLFAENC_00809 1.2e-165 L integrase core domain
HDLFAENC_00810 3.9e-122 L Transposase
HDLFAENC_00811 2.1e-30 rpsT J rRNA binding
HDLFAENC_00812 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
HDLFAENC_00813 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
HDLFAENC_00814 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HDLFAENC_00815 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HDLFAENC_00816 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HDLFAENC_00817 8.6e-65 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HDLFAENC_00818 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDLFAENC_00819 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDLFAENC_00820 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDLFAENC_00821 7.3e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HDLFAENC_00822 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HDLFAENC_00823 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
HDLFAENC_00824 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HDLFAENC_00825 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HDLFAENC_00826 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDLFAENC_00827 6.8e-81 ypmB S Protein conserved in bacteria
HDLFAENC_00828 1.9e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDLFAENC_00829 1.3e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HDLFAENC_00831 8.1e-08
HDLFAENC_00832 3.9e-30
HDLFAENC_00833 1.9e-62 tdcF 3.5.99.10 J endoribonuclease L-PSP
HDLFAENC_00834 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDLFAENC_00835 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
HDLFAENC_00836 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HDLFAENC_00837 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HDLFAENC_00838 7.7e-20 D nuclear chromosome segregation
HDLFAENC_00839 7.4e-138 yejC S cyclic nucleotide-binding protein
HDLFAENC_00840 1.2e-163 rapZ S Displays ATPase and GTPase activities
HDLFAENC_00841 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDLFAENC_00842 8.7e-162 whiA K May be required for sporulation
HDLFAENC_00843 8e-90 pepD E Dipeptidase
HDLFAENC_00844 5.8e-41 pepD E dipeptidase activity
HDLFAENC_00845 9.4e-43 K Cold-Shock Protein
HDLFAENC_00846 3.6e-224 L Transposase, Mutator family
HDLFAENC_00847 0.0 copB 3.6.3.4 P P-type ATPase
HDLFAENC_00848 1.8e-40 L Transposase
HDLFAENC_00849 4e-110 L Transposase, Mutator family
HDLFAENC_00850 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLFAENC_00851 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDLFAENC_00852 5.9e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDLFAENC_00853 2.7e-55 cysE 2.3.1.30 E serine acetyltransferase
HDLFAENC_00854 3.7e-221 L Transposase, Mutator family
HDLFAENC_00855 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HDLFAENC_00856 3.6e-114 hsdM 2.1.1.72 V type I restriction-modification system
HDLFAENC_00857 3.1e-156 glcU U Glucose uptake
HDLFAENC_00858 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
HDLFAENC_00859 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HDLFAENC_00860 2e-86 XK27_10720 D peptidase activity
HDLFAENC_00861 4.7e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
HDLFAENC_00862 1.7e-08
HDLFAENC_00863 5.1e-171 yeiH S Membrane
HDLFAENC_00864 7.2e-119 mur1 NU muramidase
HDLFAENC_00865 2.7e-34 L Transposase
HDLFAENC_00866 1.1e-78 L transposition
HDLFAENC_00867 9.9e-166 cpsY K Transcriptional regulator
HDLFAENC_00868 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDLFAENC_00869 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
HDLFAENC_00870 1.7e-103 artQ P ABC transporter (Permease
HDLFAENC_00871 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_00872 5.5e-158 aatB ET ABC transporter substrate-binding protein
HDLFAENC_00873 5.2e-35 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLFAENC_00874 3.9e-122 L Transposase
HDLFAENC_00875 1.2e-165 L integrase core domain
HDLFAENC_00876 3.3e-144 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLFAENC_00877 2.1e-07
HDLFAENC_00878 4e-59 adhP 1.1.1.1 C alcohol dehydrogenase
HDLFAENC_00879 2.7e-77 adhP 1.1.1.1 C alcohol dehydrogenase
HDLFAENC_00880 8.2e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HDLFAENC_00881 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDLFAENC_00882 2e-126 gntR1 K transcriptional
HDLFAENC_00883 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDLFAENC_00884 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDLFAENC_00885 3.1e-87 niaX
HDLFAENC_00886 6.6e-90 niaR S small molecule binding protein (contains 3H domain)
HDLFAENC_00887 4.8e-128 K DNA-binding helix-turn-helix protein
HDLFAENC_00888 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDLFAENC_00889 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLFAENC_00890 4.1e-167 GK ROK family
HDLFAENC_00891 2e-157 dprA LU DNA protecting protein DprA
HDLFAENC_00892 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDLFAENC_00893 6.7e-153 S TraX protein
HDLFAENC_00894 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLFAENC_00895 9e-251 T PhoQ Sensor
HDLFAENC_00896 2.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDLFAENC_00897 3.1e-74 XK27_05470 E Methionine synthase
HDLFAENC_00898 2e-63 XK27_05470 E Methionine synthase
HDLFAENC_00899 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HDLFAENC_00900 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLFAENC_00901 6.6e-54 IQ Acetoin reductase
HDLFAENC_00902 3.9e-19 IQ Acetoin reductase
HDLFAENC_00903 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDLFAENC_00904 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HDLFAENC_00907 1.3e-212 pqqE C radical SAM domain protein
HDLFAENC_00908 1.2e-129 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HDLFAENC_00909 6.6e-61 EGP Major facilitator Superfamily
HDLFAENC_00910 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDLFAENC_00911 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HDLFAENC_00912 5.9e-189 L Transposase
HDLFAENC_00913 3.1e-40 L DDE domain
HDLFAENC_00914 1.1e-60 L Integrase
HDLFAENC_00915 1.5e-75 tspO T TspO/MBR family
HDLFAENC_00916 2.5e-127 L Transposase, Mutator family
HDLFAENC_00917 5.4e-68 L Transposase
HDLFAENC_00918 7e-105 Z012_04635 K Helix-turn-helix XRE-family like proteins
HDLFAENC_00920 1e-89 C 4Fe-4S single cluster domain
HDLFAENC_00921 1.4e-137 C Iron-sulfur cluster-binding domain
HDLFAENC_00923 3.5e-155 V AAA domain, putative AbiEii toxin, Type IV TA system
HDLFAENC_00924 2.5e-33 S ABC-2 type transporter
HDLFAENC_00925 1.3e-97
HDLFAENC_00927 1.5e-22 L COG2801 Transposase and inactivated derivatives
HDLFAENC_00928 5.5e-30 L COG2801 Transposase and inactivated derivatives
HDLFAENC_00929 5.1e-143 K Helix-turn-helix XRE-family like proteins
HDLFAENC_00932 7e-10 2.7.7.73, 2.7.7.80 H ThiF family
HDLFAENC_00934 3.5e-283 P ABC transporter transmembrane region
HDLFAENC_00935 1.6e-208 L Transposase
HDLFAENC_00936 5.3e-117 V ABC transporter (Permease
HDLFAENC_00937 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLFAENC_00938 1.2e-97 K Transcriptional regulator, TetR family
HDLFAENC_00939 5.2e-159 czcD P cation diffusion facilitator family transporter
HDLFAENC_00940 2.3e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDLFAENC_00941 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HDLFAENC_00942 6e-08 S Hydrolases of the alpha beta superfamily
HDLFAENC_00943 1.1e-15 S Alpha/beta hydrolase of unknown function (DUF915)
HDLFAENC_00944 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
HDLFAENC_00947 2.6e-143 2.4.2.3 F Phosphorylase superfamily
HDLFAENC_00948 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HDLFAENC_00949 2.1e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
HDLFAENC_00950 1.6e-32 yclQ P ABC-type enterochelin transport system, periplasmic component
HDLFAENC_00951 1.5e-72 dinF V Mate efflux family protein
HDLFAENC_00952 6.3e-12 dinF V Mate efflux family protein
HDLFAENC_00953 6e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HDLFAENC_00954 2.5e-138 L Transposase
HDLFAENC_00955 9e-89 FNV0100 F Belongs to the Nudix hydrolase family
HDLFAENC_00956 3.5e-28 3.4.13.21 I Protein conserved in bacteria
HDLFAENC_00957 7.3e-13 L Helix-turn-helix domain of transposase family ISL3
HDLFAENC_00958 2.7e-111 S TraX protein
HDLFAENC_00959 1.1e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HDLFAENC_00960 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HDLFAENC_00961 9.3e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDLFAENC_00962 2.2e-182 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLFAENC_00963 8.3e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLFAENC_00964 6.8e-133 cas6 S Pfam:DUF2276
HDLFAENC_00965 0.0 csm1 S CRISPR-associated protein Csm1 family
HDLFAENC_00966 5.6e-62 csm2 L Pfam:DUF310
HDLFAENC_00967 3.1e-116 csm3 L RAMP superfamily
HDLFAENC_00968 5.2e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
HDLFAENC_00969 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
HDLFAENC_00970 3e-14 csm6 S Psort location Cytoplasmic, score
HDLFAENC_00971 7.5e-37 csm6 S Psort location Cytoplasmic, score
HDLFAENC_00972 2.2e-22 csm6 S Psort location Cytoplasmic, score
HDLFAENC_00973 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDLFAENC_00974 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDLFAENC_00976 4.7e-48 nylA 3.5.1.4 J Belongs to the amidase family
HDLFAENC_00977 1.8e-265 dtpT E transporter
HDLFAENC_00978 3.9e-105 nylA 3.5.1.4 J Belongs to the amidase family
HDLFAENC_00979 9.7e-133 yckB ET Belongs to the bacterial solute-binding protein 3 family
HDLFAENC_00980 4.1e-66 yecS P ABC transporter (Permease
HDLFAENC_00981 2.3e-20 yecS P amino acid transport
HDLFAENC_00983 1.5e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HDLFAENC_00984 1.9e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HDLFAENC_00985 5.9e-103 yfiF3 K sequence-specific DNA binding
HDLFAENC_00986 8.8e-22 bglC K Transcriptional regulator
HDLFAENC_00987 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDLFAENC_00988 9e-240 agcS E (Alanine) symporter
HDLFAENC_00989 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDLFAENC_00990 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
HDLFAENC_00991 7e-56 Q phosphatase activity
HDLFAENC_00992 5.9e-29 S haloacid dehalogenase-like hydrolase
HDLFAENC_00993 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDLFAENC_00994 9e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HDLFAENC_00995 5.1e-142 XK27_04775 S hemerythrin HHE cation binding domain
HDLFAENC_00996 2e-77 XK27_04775 S hemerythrin HHE cation binding domain
HDLFAENC_00997 1.1e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDLFAENC_00998 5.9e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDLFAENC_00999 4.5e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDLFAENC_01000 5.6e-43 yktA S Belongs to the UPF0223 family
HDLFAENC_01001 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HDLFAENC_01002 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HDLFAENC_01003 3.3e-158 pstS P phosphate
HDLFAENC_01004 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HDLFAENC_01005 1.2e-155 pstA P phosphate transport system permease
HDLFAENC_01006 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLFAENC_01007 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLFAENC_01008 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HDLFAENC_01009 0.0 pepN 3.4.11.2 E aminopeptidase
HDLFAENC_01010 2.7e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HDLFAENC_01012 8.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
HDLFAENC_01013 3.1e-10
HDLFAENC_01014 4.4e-10
HDLFAENC_01015 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDLFAENC_01016 1.7e-295 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HDLFAENC_01017 1.9e-181 malR K Transcriptional regulator
HDLFAENC_01018 3.2e-17 malX G ABC transporter
HDLFAENC_01019 3.8e-12 malX G maltose binding
HDLFAENC_01020 2.3e-27 malX G maltose binding
HDLFAENC_01021 2.7e-110 malF P ABC transporter (Permease
HDLFAENC_01022 4.6e-25 tatA U protein secretion
HDLFAENC_01023 1.1e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDLFAENC_01024 3.7e-299 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HDLFAENC_01025 1.5e-233 ycdB P peroxidase
HDLFAENC_01026 2.7e-152 ycdO P periplasmic lipoprotein involved in iron transport
HDLFAENC_01027 1.7e-177 fatB P ABC-type enterochelin transport system, periplasmic component
HDLFAENC_01028 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
HDLFAENC_01029 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDLFAENC_01030 8.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDLFAENC_01031 4.3e-125 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01032 2.6e-55 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01033 2.6e-209 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01034 3.5e-107 3.5.1.28 NU amidase activity
HDLFAENC_01035 1.7e-95 3.5.1.28 NU amidase activity
HDLFAENC_01036 9.2e-81 3.5.1.28 NU amidase activity
HDLFAENC_01037 1.2e-65 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLFAENC_01039 0.0 lpdA 1.8.1.4 C Dehydrogenase
HDLFAENC_01040 4.8e-196 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDLFAENC_01041 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDLFAENC_01042 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HDLFAENC_01043 6.7e-101 hpk9 2.7.13.3 T protein histidine kinase activity
HDLFAENC_01044 8.6e-10 2.7.13.3 T protein histidine kinase activity
HDLFAENC_01045 1.2e-52 2.7.13.3 T protein histidine kinase activity
HDLFAENC_01046 4.5e-115 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
HDLFAENC_01047 6e-85 cas3 L CRISPR-associated helicase cas3
HDLFAENC_01048 0.0 S the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01049 1.2e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDLFAENC_01050 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDLFAENC_01051 1.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDLFAENC_01052 2.6e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_01053 1.6e-20 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_01054 1.4e-44 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_01055 1.7e-86 3.4.16.4 M Belongs to the peptidase S11 family
HDLFAENC_01056 1.1e-158 rssA S Phospholipase, patatin family
HDLFAENC_01057 3.9e-84 estA E GDSL-like protein
HDLFAENC_01058 1.8e-292 S unusual protein kinase
HDLFAENC_01059 1.3e-39 S granule-associated protein
HDLFAENC_01060 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLFAENC_01061 2.3e-33 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HDLFAENC_01062 5.2e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLFAENC_01063 7.2e-26 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLFAENC_01064 6.5e-199 S hmm pf01594
HDLFAENC_01065 1.1e-87 G Belongs to the phosphoglycerate mutase family
HDLFAENC_01066 5.8e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
HDLFAENC_01067 1.5e-95 V VanZ like family
HDLFAENC_01069 1.5e-203 L Transposase
HDLFAENC_01070 2.1e-166 M Glycosyltransferase, group 2 family protein
HDLFAENC_01071 2e-62 ycbI M Glycosyl transferase family 2
HDLFAENC_01072 6.4e-103
HDLFAENC_01073 1.6e-145 M Glycosyltransferase sugar-binding region containing DXD motif
HDLFAENC_01074 1.6e-85 pssE S Glycosyltransferase family 28 C-terminal domain
HDLFAENC_01075 2e-79 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HDLFAENC_01076 4.2e-65 cpsE M Bacterial sugar transferase
HDLFAENC_01077 1.7e-102 cpsE M Bacterial sugar transferase
HDLFAENC_01078 2.5e-21 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HDLFAENC_01079 5.5e-112 XK27_06780 V FtsX-like permease family
HDLFAENC_01080 3.3e-153 XK27_06780 V FtsX-like permease family
HDLFAENC_01081 2.3e-115 XK27_06780 V FtsX-like permease family
HDLFAENC_01082 1.8e-215 L Transposase
HDLFAENC_01083 1.9e-93 2.7.8.12 GT2 S Glycosyltransferase like family 2
HDLFAENC_01084 1.2e-69 L Integrase core domain
HDLFAENC_01085 8.5e-73 tnp L DDE domain
HDLFAENC_01086 2.8e-239 cps1C S Polysaccharide biosynthesis protein
HDLFAENC_01087 7e-72 2.7.8.12 GT2 M Glycosyltransferase like family 2
HDLFAENC_01088 2.6e-12 M Glycosyltransferase like family 2
HDLFAENC_01089 8e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HDLFAENC_01090 4.5e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
HDLFAENC_01091 9.4e-108 cps4C M biosynthesis protein
HDLFAENC_01092 8.6e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HDLFAENC_01093 6.5e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HDLFAENC_01094 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HDLFAENC_01095 3.4e-92 yfeJ 6.3.5.2 F glutamine amidotransferase
HDLFAENC_01096 2.6e-10 yfeJ 6.3.5.2 F glutamine amidotransferase
HDLFAENC_01097 3.2e-54 clcA_2 P chloride
HDLFAENC_01098 1.3e-61 clcA_2 P chloride channel
HDLFAENC_01099 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HDLFAENC_01100 1.3e-73 S Protein of unknown function (DUF1697)
HDLFAENC_01101 2.7e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDLFAENC_01102 2.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDLFAENC_01103 5.7e-08 V Glucan-binding protein C
HDLFAENC_01104 2.7e-33 V Glucan-binding protein C
HDLFAENC_01105 3.4e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDLFAENC_01106 6.9e-275 pepV 3.5.1.18 E Dipeptidase
HDLFAENC_01107 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDLFAENC_01108 3.4e-48 XK27_03610 K Gnat family
HDLFAENC_01109 4.8e-16 XK27_03610 K Gnat family
HDLFAENC_01110 6.2e-24 L Transposase
HDLFAENC_01111 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDLFAENC_01112 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDLFAENC_01113 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDLFAENC_01114 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDLFAENC_01115 5e-23 M LysM domain
HDLFAENC_01116 1.5e-29 fer C Ferredoxin
HDLFAENC_01117 1.9e-89 ebsA S Family of unknown function (DUF5322)
HDLFAENC_01118 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDLFAENC_01119 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDLFAENC_01120 8.3e-224 G COG0457 FOG TPR repeat
HDLFAENC_01121 6.2e-176 yubA S permease
HDLFAENC_01122 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDLFAENC_01123 6.2e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDLFAENC_01124 5.5e-124 ftsE D cell division ATP-binding protein FtsE
HDLFAENC_01125 2.8e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDLFAENC_01126 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDLFAENC_01127 3.9e-181 yjjH S Calcineurin-like phosphoesterase
HDLFAENC_01128 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HDLFAENC_01129 0.0 pacL 3.6.3.8 P cation transport ATPase
HDLFAENC_01130 2.6e-67 ywiB S Domain of unknown function (DUF1934)
HDLFAENC_01131 8.4e-50 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HDLFAENC_01132 9.2e-147 yidA S hydrolases of the HAD superfamily
HDLFAENC_01133 1.7e-229 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HDLFAENC_01134 1.5e-34 F Protein of unknown function (DUF454)
HDLFAENC_01135 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HDLFAENC_01136 3.9e-235 vicK 2.7.13.3 T Histidine kinase
HDLFAENC_01137 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLFAENC_01138 3.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_01139 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDLFAENC_01140 2.7e-118 gltJ P ABC transporter (Permease
HDLFAENC_01141 1.7e-111 tcyB_2 P ABC transporter (permease)
HDLFAENC_01142 5.5e-129 endA F DNA RNA non-specific endonuclease
HDLFAENC_01143 1.6e-25 epuA S DNA-directed RNA polymerase subunit beta
HDLFAENC_01144 3.8e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLFAENC_01145 2e-09 S Protein of unknown function (DUF1146)
HDLFAENC_01146 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLFAENC_01147 1.7e-25 G Domain of unknown function (DUF4832)
HDLFAENC_01148 2.3e-202 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDLFAENC_01149 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDLFAENC_01151 1.2e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLFAENC_01152 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HDLFAENC_01153 2.4e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDLFAENC_01154 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
HDLFAENC_01157 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
HDLFAENC_01160 7.9e-21 E Zn peptidase
HDLFAENC_01162 1.8e-177 S Phage integrase family
HDLFAENC_01164 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDLFAENC_01165 1.4e-218 XK27_05110 P chloride
HDLFAENC_01166 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HDLFAENC_01167 3.2e-281 clcA P Chloride transporter, ClC family
HDLFAENC_01168 5.1e-75 fld C Flavodoxin
HDLFAENC_01169 2.5e-14 XK27_08880
HDLFAENC_01170 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HDLFAENC_01171 1.6e-151 estA CE1 S Putative esterase
HDLFAENC_01172 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLFAENC_01173 1.2e-135 XK27_08845 S abc transporter atp-binding protein
HDLFAENC_01174 4.4e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HDLFAENC_01175 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
HDLFAENC_01176 3.2e-17 S Domain of unknown function (DUF4649)
HDLFAENC_01178 2.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01179 5.4e-27 Q the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01181 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01183 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDLFAENC_01184 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDLFAENC_01185 0.0 dnaE 2.7.7.7 L DNA polymerase
HDLFAENC_01186 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HDLFAENC_01187 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDLFAENC_01188 2e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDLFAENC_01189 1.1e-41 ysdA L Membrane
HDLFAENC_01190 4.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDLFAENC_01191 7.6e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDLFAENC_01192 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLFAENC_01193 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HDLFAENC_01195 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDLFAENC_01196 1.3e-94 ypmS S Protein conserved in bacteria
HDLFAENC_01197 2.5e-145 ypmR E lipolytic protein G-D-S-L family
HDLFAENC_01198 1.7e-148 DegV S DegV family
HDLFAENC_01199 7.6e-305 recN L May be involved in recombinational repair of damaged DNA
HDLFAENC_01200 1.2e-71 argR K arginine binding
HDLFAENC_01201 2.1e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDLFAENC_01202 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDLFAENC_01203 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HDLFAENC_01204 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLFAENC_01207 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDLFAENC_01208 2.9e-125 dnaD
HDLFAENC_01209 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDLFAENC_01210 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDLFAENC_01211 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HDLFAENC_01212 1.1e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLFAENC_01213 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDLFAENC_01214 1.2e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HDLFAENC_01215 1.9e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDLFAENC_01216 2.4e-238 rodA D Belongs to the SEDS family
HDLFAENC_01217 1.3e-91 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HDLFAENC_01218 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HDLFAENC_01219 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HDLFAENC_01220 2.4e-121 ylfI S tigr01906
HDLFAENC_01221 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDLFAENC_01222 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HDLFAENC_01223 2.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HDLFAENC_01226 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDLFAENC_01227 3.2e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDLFAENC_01228 9.2e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDLFAENC_01229 1.3e-207 yurR 1.4.5.1 E oxidoreductase
HDLFAENC_01230 8.6e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
HDLFAENC_01231 2.4e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
HDLFAENC_01232 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDLFAENC_01233 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDLFAENC_01234 1.3e-70 gtrA S GtrA-like protein
HDLFAENC_01235 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDLFAENC_01236 6e-169 ybbR S Protein conserved in bacteria
HDLFAENC_01237 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDLFAENC_01238 2.2e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HDLFAENC_01239 8.7e-150 cobQ S glutamine amidotransferase
HDLFAENC_01240 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLFAENC_01241 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HDLFAENC_01243 0.0 uup S abc transporter atp-binding protein
HDLFAENC_01244 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HDLFAENC_01245 1.3e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDLFAENC_01246 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDLFAENC_01247 1.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HDLFAENC_01248 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDLFAENC_01249 7.9e-39 ptsH G phosphocarrier protein Hpr
HDLFAENC_01250 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
HDLFAENC_01251 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
HDLFAENC_01252 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDLFAENC_01253 2.2e-34 nrdH O Glutaredoxin
HDLFAENC_01254 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLFAENC_01255 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLFAENC_01256 4e-44
HDLFAENC_01257 9.4e-71 L Transposase (IS116 IS110 IS902 family)
HDLFAENC_01258 5.2e-57 L Transposase (IS116 IS110 IS902 family)
HDLFAENC_01259 1.5e-164 ypuA S secreted protein
HDLFAENC_01260 1.6e-54 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
HDLFAENC_01261 1.3e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HDLFAENC_01262 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLFAENC_01263 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDLFAENC_01264 3.3e-250 L Transposase
HDLFAENC_01265 2.8e-257 noxE P NADH oxidase
HDLFAENC_01266 2.5e-294 yfmM S abc transporter atp-binding protein
HDLFAENC_01267 1.4e-58 XK27_01265 S ECF-type riboflavin transporter, S component
HDLFAENC_01268 5.1e-55 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HDLFAENC_01269 6.8e-18 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HDLFAENC_01270 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HDLFAENC_01271 2e-86 S ECF-type riboflavin transporter, S component
HDLFAENC_01273 1.2e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDLFAENC_01274 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HDLFAENC_01277 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLFAENC_01278 2.7e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLFAENC_01279 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDLFAENC_01280 0.0 smc D Required for chromosome condensation and partitioning
HDLFAENC_01281 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDLFAENC_01282 3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDLFAENC_01283 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDLFAENC_01284 4.8e-47 alkD L Dna alkylation repair
HDLFAENC_01285 1.6e-91 pat 2.3.1.183 M acetyltransferase
HDLFAENC_01286 3e-13
HDLFAENC_01287 1.8e-22
HDLFAENC_01288 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDLFAENC_01289 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDLFAENC_01290 1.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HDLFAENC_01291 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
HDLFAENC_01292 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase
HDLFAENC_01293 3.3e-26
HDLFAENC_01294 1.4e-144 S ABC-2 family transporter protein
HDLFAENC_01295 1.2e-97 S transport system, permease component
HDLFAENC_01296 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDLFAENC_01297 1.5e-192 desK 2.7.13.3 T Histidine kinase
HDLFAENC_01298 4.8e-134 yvfS V ABC-2 type transporter
HDLFAENC_01299 5.3e-156 XK27_09825 V abc transporter atp-binding protein
HDLFAENC_01302 1.1e-162 yocS S Transporter
HDLFAENC_01303 2.8e-84 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HDLFAENC_01304 2.9e-34 XK27_05000 S metal cluster binding
HDLFAENC_01305 0.0 V ABC transporter (permease)
HDLFAENC_01306 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HDLFAENC_01307 3.3e-159 T Histidine kinase
HDLFAENC_01308 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLFAENC_01309 5e-76 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDLFAENC_01311 1.1e-75 pbuX F xanthine permease
HDLFAENC_01312 5.9e-115 pbuX F xanthine permease
HDLFAENC_01313 1.3e-246 norM V Multidrug efflux pump
HDLFAENC_01314 6.3e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLFAENC_01315 5.6e-234 brnQ E Component of the transport system for branched-chain amino acids
HDLFAENC_01316 1.9e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLFAENC_01317 6.3e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLFAENC_01318 9.6e-26 csbD K CsbD-like
HDLFAENC_01319 6.2e-228 yfnA E amino acid
HDLFAENC_01320 1.4e-107 XK27_02070 S nitroreductase
HDLFAENC_01321 5.5e-95 1.13.11.2 S glyoxalase
HDLFAENC_01322 3.6e-76 ywnA K Transcriptional regulator
HDLFAENC_01323 1.3e-154 E Alpha/beta hydrolase of unknown function (DUF915)
HDLFAENC_01324 1e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLFAENC_01325 2.2e-111 drgA C Nitroreductase
HDLFAENC_01326 4.6e-87 yoaK S Protein of unknown function (DUF1275)
HDLFAENC_01328 1.7e-159 yvgN C reductase
HDLFAENC_01329 6.7e-101 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLFAENC_01330 1.5e-52 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLFAENC_01331 7.8e-285 XK27_07020 S Belongs to the UPF0371 family
HDLFAENC_01333 6.7e-38 BP1961 P nitric oxide dioxygenase activity
HDLFAENC_01334 4.4e-36 K the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01335 2.4e-54 K response regulator
HDLFAENC_01336 5.5e-64 S Signal peptide protein, YSIRK family
HDLFAENC_01338 1.6e-58
HDLFAENC_01339 8.8e-262 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLFAENC_01340 1.8e-93
HDLFAENC_01341 1.4e-37 IQ PFAM AMP-dependent synthetase and ligase
HDLFAENC_01342 6.9e-08 IQ PFAM AMP-dependent synthetase and ligase
HDLFAENC_01343 5.8e-109 MA20_06410 E LysE type translocator
HDLFAENC_01344 2.1e-07
HDLFAENC_01345 5.5e-10
HDLFAENC_01346 0.0 M family 8
HDLFAENC_01347 3.8e-21
HDLFAENC_01348 0.0 sbcC L ATPase involved in DNA repair
HDLFAENC_01349 1.7e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDLFAENC_01350 0.0 lacL 3.2.1.23 G -beta-galactosidase
HDLFAENC_01351 0.0 lacS G transporter
HDLFAENC_01352 3.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDLFAENC_01353 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLFAENC_01354 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HDLFAENC_01355 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDLFAENC_01356 2.6e-183 galR K Transcriptional regulator
HDLFAENC_01357 9.7e-08 L Integrase core domain protein
HDLFAENC_01358 2.9e-193 M translation initiation factor activity
HDLFAENC_01359 2.3e-67 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HDLFAENC_01360 8.5e-102 V abc transporter atp-binding protein
HDLFAENC_01361 1e-41 V (ABC) transporter
HDLFAENC_01362 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HDLFAENC_01363 5.9e-62 L Transposase
HDLFAENC_01364 3.1e-119 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01365 9.3e-30 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01366 5.9e-51 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01367 1.5e-121 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLFAENC_01368 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDLFAENC_01369 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDLFAENC_01370 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDLFAENC_01371 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDLFAENC_01374 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDLFAENC_01375 5.8e-175 vraS 2.7.13.3 T Histidine kinase
HDLFAENC_01376 3.7e-120 yvqF KT membrane
HDLFAENC_01377 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDLFAENC_01378 2.2e-131 stp 3.1.3.16 T phosphatase
HDLFAENC_01379 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDLFAENC_01380 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDLFAENC_01381 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDLFAENC_01382 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HDLFAENC_01383 2.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDLFAENC_01384 3.4e-218 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDLFAENC_01385 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
HDLFAENC_01386 6.9e-147 supH S overlaps another CDS with the same product name
HDLFAENC_01387 8.6e-63 yvoA_1 K Transcriptional
HDLFAENC_01388 9.8e-121 skfE V abc transporter atp-binding protein
HDLFAENC_01389 3.3e-133 V ATPase activity
HDLFAENC_01390 4.3e-172 oppF P Belongs to the ABC transporter superfamily
HDLFAENC_01391 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HDLFAENC_01392 4.9e-168 amiD P ABC transporter (Permease
HDLFAENC_01393 7.1e-278 amiC P ABC transporter (Permease
HDLFAENC_01394 6.8e-142 amiA E ABC transporter, substrate-binding protein, family 5
HDLFAENC_01395 6.3e-160 amiA E ABC transporter, substrate-binding protein, family 5
HDLFAENC_01396 1.4e-226 L Transposase
HDLFAENC_01397 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HDLFAENC_01398 1.2e-24 oppF P Belongs to the ABC transporter superfamily
HDLFAENC_01399 2e-46 oppF P Belongs to the ABC transporter superfamily
HDLFAENC_01400 1.7e-38 tatD L Hydrolase, tatd
HDLFAENC_01401 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
HDLFAENC_01402 1.8e-84 L PFAM Integrase catalytic region
HDLFAENC_01403 5.1e-27 L transposition
HDLFAENC_01404 2.8e-22 L transposase activity
HDLFAENC_01405 3e-37 L transposase activity
HDLFAENC_01406 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDLFAENC_01407 2.4e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HDLFAENC_01408 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDLFAENC_01409 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HDLFAENC_01410 1.5e-103 yjbK S Adenylate cyclase
HDLFAENC_01411 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLFAENC_01412 4.1e-206 iscS 2.8.1.7 E Cysteine desulfurase
HDLFAENC_01413 2e-58 XK27_04120 S Putative amino acid metabolism
HDLFAENC_01414 6.3e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDLFAENC_01415 6.1e-131 puuD T peptidase C26
HDLFAENC_01416 6.9e-119 radC E Belongs to the UPF0758 family
HDLFAENC_01417 0.0 rgpF M Rhamnan synthesis protein F
HDLFAENC_01418 1.7e-193 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDLFAENC_01419 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDLFAENC_01420 2.8e-143 rgpC GM Transport permease protein
HDLFAENC_01421 7.5e-180 rgpB GT2 M Glycosyltransferase, group 2 family protein
HDLFAENC_01422 1.1e-225 rgpA GT4 M Domain of unknown function (DUF1972)
HDLFAENC_01423 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
HDLFAENC_01424 8.9e-221 amrA S polysaccharide biosynthetic process
HDLFAENC_01425 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
HDLFAENC_01426 7.6e-126 ycbB S Glycosyl transferase family 2
HDLFAENC_01427 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDLFAENC_01428 3.9e-243
HDLFAENC_01429 2.6e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HDLFAENC_01430 6.3e-252 M Psort location CytoplasmicMembrane, score
HDLFAENC_01431 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HDLFAENC_01432 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDLFAENC_01433 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDLFAENC_01434 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDLFAENC_01435 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
HDLFAENC_01436 2.8e-202 arcT 2.6.1.1 E Aminotransferase
HDLFAENC_01437 7.2e-136 ET ABC transporter
HDLFAENC_01438 2.7e-141 ET Belongs to the bacterial solute-binding protein 3 family
HDLFAENC_01439 2.2e-84 mutT 3.6.1.55 F Nudix family
HDLFAENC_01440 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDLFAENC_01441 1.1e-56 V CAAX protease self-immunity
HDLFAENC_01442 7.6e-32 S CAAX amino terminal protease family protein
HDLFAENC_01443 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HDLFAENC_01444 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_01445 1.1e-16 XK27_00735
HDLFAENC_01446 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDLFAENC_01448 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLFAENC_01451 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HDLFAENC_01452 3e-37 ycaO O OsmC-like protein
HDLFAENC_01454 5.9e-155 EG Permeases of the drug metabolite transporter (DMT) superfamily
HDLFAENC_01455 9.7e-115 serB 3.1.3.3 E phosphoserine phosphatase
HDLFAENC_01456 3.9e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDLFAENC_01457 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLFAENC_01458 2.6e-109 3.1.3.18 S IA, variant 1
HDLFAENC_01459 2.2e-117 lrgB M effector of murein hydrolase
HDLFAENC_01460 2.2e-58 lrgA S Effector of murein hydrolase LrgA
HDLFAENC_01462 8.3e-60 arsC 1.20.4.1 P Belongs to the ArsC family
HDLFAENC_01463 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLFAENC_01464 1.3e-104 wecD M Acetyltransferase (GNAT) domain
HDLFAENC_01465 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDLFAENC_01466 7.5e-118 GK ROK family
HDLFAENC_01467 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
HDLFAENC_01468 2.2e-77 XK27_08050 O stress-induced mitochondrial fusion
HDLFAENC_01469 3.1e-23 XK27_08050 O HflC and HflK could regulate a protease
HDLFAENC_01471 2.3e-206 potD P spermidine putrescine ABC transporter
HDLFAENC_01472 4.3e-133 potC P ABC-type spermidine putrescine transport system, permease component II
HDLFAENC_01473 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HDLFAENC_01474 7.3e-214 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDLFAENC_01475 4.6e-171 murB 1.3.1.98 M cell wall formation
HDLFAENC_01476 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDLFAENC_01477 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDLFAENC_01478 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HDLFAENC_01479 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDLFAENC_01480 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HDLFAENC_01481 0.0 ydaO E amino acid
HDLFAENC_01482 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDLFAENC_01483 4.1e-37 ylqC L Belongs to the UPF0109 family
HDLFAENC_01484 3.2e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDLFAENC_01485 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HDLFAENC_01486 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
HDLFAENC_01487 2.1e-74 S QueT transporter
HDLFAENC_01488 4.3e-27 L Transposase
HDLFAENC_01489 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDLFAENC_01490 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLFAENC_01491 1.7e-85 ccl S cog cog4708
HDLFAENC_01492 6.4e-160 rbn E Belongs to the UPF0761 family
HDLFAENC_01493 4.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HDLFAENC_01494 8.6e-232 ytoI K transcriptional regulator containing CBS domains
HDLFAENC_01495 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HDLFAENC_01496 6.9e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLFAENC_01497 0.0 comEC S Competence protein ComEC
HDLFAENC_01498 1.2e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HDLFAENC_01499 1.3e-142 plsC 2.3.1.51 I Acyltransferase
HDLFAENC_01500 9.3e-79 nodB3 G polysaccharide deacetylase
HDLFAENC_01501 2.3e-47 nodB3 G polysaccharide deacetylase
HDLFAENC_01502 1.2e-137 yabB 2.1.1.223 L Methyltransferase
HDLFAENC_01503 1.3e-41 yazA L endonuclease containing a URI domain
HDLFAENC_01504 4.8e-256 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDLFAENC_01505 3e-154 corA P CorA-like protein
HDLFAENC_01506 2.5e-62 yjqA S Bacterial PH domain
HDLFAENC_01507 1.7e-99 thiT S Thiamine transporter
HDLFAENC_01508 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HDLFAENC_01509 9.8e-198 yjbB G Permeases of the major facilitator superfamily
HDLFAENC_01510 8.9e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDLFAENC_01511 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
HDLFAENC_01512 3.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDLFAENC_01516 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HDLFAENC_01517 5.2e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_01518 7.8e-107 P ABC transporter (Permease
HDLFAENC_01519 6e-115 papP P ABC transporter (Permease
HDLFAENC_01520 7.1e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDLFAENC_01521 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HDLFAENC_01522 0.0 copA 3.6.3.54 P P-type ATPase
HDLFAENC_01523 4.7e-73 copY K Copper transport repressor, CopY TcrY family
HDLFAENC_01524 4.1e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDLFAENC_01525 5.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDLFAENC_01526 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HDLFAENC_01527 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HDLFAENC_01528 7.3e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDLFAENC_01529 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HDLFAENC_01530 2.5e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDLFAENC_01531 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HDLFAENC_01532 3.2e-56
HDLFAENC_01533 0.0 ctpE P E1-E2 ATPase
HDLFAENC_01534 2.7e-25
HDLFAENC_01535 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDLFAENC_01536 6.6e-47 L transposase activity
HDLFAENC_01537 1.2e-129 K transcriptional regulator, MerR family
HDLFAENC_01538 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
HDLFAENC_01539 1.5e-41 WQ51_02910 S Protein of unknown function, DUF536
HDLFAENC_01540 1.6e-63 XK27_02560 S cog cog2151
HDLFAENC_01541 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDLFAENC_01542 7.7e-227 ytfP S Flavoprotein
HDLFAENC_01544 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDLFAENC_01545 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HDLFAENC_01546 3.5e-183 ecsB U ABC transporter
HDLFAENC_01547 2.3e-133 ecsA V abc transporter atp-binding protein
HDLFAENC_01548 1.3e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HDLFAENC_01549 4.6e-11
HDLFAENC_01550 7.3e-107
HDLFAENC_01551 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HDLFAENC_01552 2.6e-205 ylbM S Belongs to the UPF0348 family
HDLFAENC_01553 2e-140 yqeM Q Methyltransferase domain protein
HDLFAENC_01554 3.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDLFAENC_01555 8.9e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HDLFAENC_01556 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDLFAENC_01557 3.5e-49 yhbY J RNA-binding protein
HDLFAENC_01558 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HDLFAENC_01559 1.8e-98 yqeG S hydrolase of the HAD superfamily
HDLFAENC_01560 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDLFAENC_01561 1.2e-58
HDLFAENC_01562 1.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLFAENC_01563 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDLFAENC_01564 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLFAENC_01565 1.5e-255 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLFAENC_01566 2.3e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLFAENC_01567 1.4e-153 hlpA M Belongs to the NlpA lipoprotein family
HDLFAENC_01568 3.4e-100 pncA Q isochorismatase
HDLFAENC_01569 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HDLFAENC_01570 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HDLFAENC_01571 1.5e-74 XK27_03180 T universal stress protein
HDLFAENC_01573 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLFAENC_01574 4.4e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HDLFAENC_01575 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HDLFAENC_01576 0.0 yjcE P NhaP-type Na H and K H antiporters
HDLFAENC_01578 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HDLFAENC_01579 8.4e-184 yhcC S radical SAM protein
HDLFAENC_01580 8.4e-196 ylbL T Belongs to the peptidase S16 family
HDLFAENC_01581 3.9e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDLFAENC_01582 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HDLFAENC_01583 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDLFAENC_01584 2.8e-08 S Protein of unknown function (DUF4059)
HDLFAENC_01585 3.4e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
HDLFAENC_01586 3.4e-172 yxeN P ABC transporter (Permease
HDLFAENC_01587 7.7e-149 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDLFAENC_01589 7.7e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLFAENC_01590 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HDLFAENC_01591 8.6e-66 cah 4.2.1.1 P carbonic anhydrase
HDLFAENC_01592 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLFAENC_01593 4.6e-43 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HDLFAENC_01594 1.6e-09 recN L Plasmid recombination enzyme
HDLFAENC_01595 2.3e-75 L DNA integration
HDLFAENC_01596 4.3e-121 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
HDLFAENC_01597 7.6e-127 ybbM S transport system, permease component
HDLFAENC_01598 6.8e-116 ybbL S abc transporter atp-binding protein
HDLFAENC_01599 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HDLFAENC_01600 4.6e-140 cppA E CppA N-terminal
HDLFAENC_01601 2.4e-30 V CAAX protease self-immunity
HDLFAENC_01602 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HDLFAENC_01603 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDLFAENC_01606 3e-47 spiA K sequence-specific DNA binding
HDLFAENC_01607 9.5e-140 blpT
HDLFAENC_01608 1.5e-118 L Transposase
HDLFAENC_01609 1.2e-165 L integrase core domain
HDLFAENC_01614 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
HDLFAENC_01615 8.9e-133 agrA KT phosphorelay signal transduction system
HDLFAENC_01616 1.1e-237 blpH 2.7.13.3 T protein histidine kinase activity
HDLFAENC_01618 1.3e-157 mesE M Transport protein ComB
HDLFAENC_01619 7.9e-44 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLFAENC_01620 1.8e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLFAENC_01621 9.8e-74 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLFAENC_01622 1.7e-140 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLFAENC_01623 0.0 mdlB V abc transporter atp-binding protein
HDLFAENC_01624 0.0 mdlA V abc transporter atp-binding protein
HDLFAENC_01626 4.2e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
HDLFAENC_01627 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDLFAENC_01628 1.1e-69 yutD J protein conserved in bacteria
HDLFAENC_01629 3.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDLFAENC_01631 3.6e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDLFAENC_01632 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDLFAENC_01633 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HDLFAENC_01634 5.6e-47 ftsL D cell division protein FtsL
HDLFAENC_01635 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDLFAENC_01636 3.7e-52
HDLFAENC_01637 4.5e-43
HDLFAENC_01638 6.5e-10
HDLFAENC_01639 3.5e-10 D nuclear chromosome segregation
HDLFAENC_01640 4.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDLFAENC_01641 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDLFAENC_01642 6e-283 XK27_00765
HDLFAENC_01643 7.5e-89 ecsA_2 V abc transporter atp-binding protein
HDLFAENC_01644 1.1e-19 ecsA_2 V ATPase activity
HDLFAENC_01645 3e-120 S Protein of unknown function (DUF554)
HDLFAENC_01646 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDLFAENC_01647 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HDLFAENC_01648 3.4e-57 liaI S membrane
HDLFAENC_01649 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
HDLFAENC_01650 5.2e-53 KT response to antibiotic
HDLFAENC_01651 1.4e-08 KT response to antibiotic
HDLFAENC_01652 3.5e-17 KT response to antibiotic
HDLFAENC_01653 2.3e-81 yebC M Membrane
HDLFAENC_01654 8.5e-18 yebC M Membrane
HDLFAENC_01655 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HDLFAENC_01656 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HDLFAENC_01657 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDLFAENC_01658 5.2e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDLFAENC_01659 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDLFAENC_01660 4.7e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HDLFAENC_01661 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HDLFAENC_01662 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDLFAENC_01664 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLFAENC_01665 4.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HDLFAENC_01666 0.0 scrA 2.7.1.211 G pts system
HDLFAENC_01667 4.1e-291 scrB 3.2.1.26 GH32 G invertase
HDLFAENC_01668 2.9e-179 scrR K Transcriptional
HDLFAENC_01669 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDLFAENC_01670 3.4e-62 yqhY S protein conserved in bacteria
HDLFAENC_01671 2.7e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDLFAENC_01672 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
HDLFAENC_01673 1.5e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HDLFAENC_01675 8.8e-44 V 'abc transporter, ATP-binding protein
HDLFAENC_01676 8.9e-45 V 'abc transporter, ATP-binding protein
HDLFAENC_01679 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HDLFAENC_01680 5.8e-169 corA P COG0598 Mg2 and Co2 transporters
HDLFAENC_01681 3.1e-124 XK27_01040 S Pfam PF06570
HDLFAENC_01683 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDLFAENC_01684 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLFAENC_01685 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HDLFAENC_01686 9.5e-42 XK27_05745
HDLFAENC_01687 4.2e-230 mutY L A G-specific adenine glycosylase
HDLFAENC_01692 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDLFAENC_01693 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDLFAENC_01694 3.3e-92 cvpA S toxin biosynthetic process
HDLFAENC_01695 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDLFAENC_01696 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLFAENC_01697 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDLFAENC_01698 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDLFAENC_01699 8.8e-48 azlD E branched-chain amino acid
HDLFAENC_01700 1.2e-115 azlC E AzlC protein
HDLFAENC_01701 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDLFAENC_01702 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDLFAENC_01703 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HDLFAENC_01704 2.5e-33 ykzG S Belongs to the UPF0356 family
HDLFAENC_01705 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLFAENC_01706 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HDLFAENC_01707 8.5e-63 glnR K Transcriptional regulator
HDLFAENC_01708 3.3e-250 L Transposase
HDLFAENC_01709 1.8e-87 S Fusaric acid resistance protein-like
HDLFAENC_01710 3e-13
HDLFAENC_01711 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDLFAENC_01712 5.5e-42 L Transposase
HDLFAENC_01713 9.4e-46 L transposase activity
HDLFAENC_01714 2.5e-22 L Transposase
HDLFAENC_01715 1e-54 L transposition
HDLFAENC_01716 3.8e-87 L Integrase core domain protein
HDLFAENC_01717 3.3e-250 L Transposase
HDLFAENC_01718 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDLFAENC_01719 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDLFAENC_01720 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDLFAENC_01721 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDLFAENC_01722 1.1e-142 purR 2.4.2.7 F operon repressor
HDLFAENC_01723 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
HDLFAENC_01724 1.5e-172 rmuC S RmuC domain protein
HDLFAENC_01725 3.5e-117 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDLFAENC_01726 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDLFAENC_01727 9.9e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDLFAENC_01729 1.7e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDLFAENC_01730 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDLFAENC_01731 4.1e-144 tatD L Hydrolase, tatd
HDLFAENC_01732 1.5e-74 yccU S CoA-binding protein
HDLFAENC_01733 4.8e-51 trxA O Belongs to the thioredoxin family
HDLFAENC_01734 6.6e-142 S Macro domain protein
HDLFAENC_01735 4.5e-09 L thioesterase
HDLFAENC_01736 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
HDLFAENC_01740 4.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDLFAENC_01741 1.1e-83 L Transposase
HDLFAENC_01742 1e-13 rpmH J Ribosomal protein L34
HDLFAENC_01744 1.9e-184 jag S RNA-binding protein
HDLFAENC_01745 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLFAENC_01746 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDLFAENC_01747 1e-262 argH 4.3.2.1 E Argininosuccinate lyase
HDLFAENC_01748 7.5e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDLFAENC_01749 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDLFAENC_01750 3.9e-81 amiA E transmembrane transport
HDLFAENC_01751 3.5e-73 amiA E transmembrane transport
HDLFAENC_01752 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDLFAENC_01753 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDLFAENC_01754 9.2e-51 S Protein of unknown function (DUF3397)
HDLFAENC_01755 4.6e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HDLFAENC_01756 7.9e-35 WQ51_05710 S Mitochondrial biogenesis AIM24
HDLFAENC_01757 2.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDLFAENC_01758 2.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HDLFAENC_01759 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
HDLFAENC_01760 1.6e-35 XK27_09620 S FMN reductase (NADPH) activity
HDLFAENC_01761 4.6e-35 XK27_09620 S FMN reductase (NADPH) activity
HDLFAENC_01762 1.1e-33 XK27_09615 S FMN reductase (NADPH) activity
HDLFAENC_01763 6.5e-113 XK27_09615 C reductase
HDLFAENC_01764 8.5e-24 fnt P Formate nitrite transporter
HDLFAENC_01765 2.1e-48 fnt P Formate nitrite transporter
HDLFAENC_01766 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
HDLFAENC_01767 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDLFAENC_01768 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDLFAENC_01769 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HDLFAENC_01770 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDLFAENC_01771 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDLFAENC_01772 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDLFAENC_01773 3.6e-21 S glycolate biosynthetic process
HDLFAENC_01774 4e-65 S phosphatase activity
HDLFAENC_01775 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
HDLFAENC_01778 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDLFAENC_01779 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLFAENC_01780 8.3e-37 yeeD O sulfur carrier activity
HDLFAENC_01781 2.1e-188 yeeE S Sulphur transport
HDLFAENC_01782 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLFAENC_01783 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDLFAENC_01784 1.8e-09 S Domain of unknown function (DUF4651)
HDLFAENC_01785 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HDLFAENC_01786 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDLFAENC_01787 1.9e-110 S CAAX amino terminal protease family protein
HDLFAENC_01789 1.4e-66 V CAAX protease self-immunity
HDLFAENC_01790 8.8e-27 lanR K sequence-specific DNA binding
HDLFAENC_01791 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLFAENC_01792 1.3e-176 ytxK 2.1.1.72 L DNA methylase
HDLFAENC_01793 6.8e-13 comGF U Putative Competence protein ComGF
HDLFAENC_01794 1.5e-71 comGF U Competence protein ComGF
HDLFAENC_01795 1.4e-15 NU Type II secretory pathway pseudopilin
HDLFAENC_01796 3e-57 cglD NU Competence protein
HDLFAENC_01797 8.5e-43 comGC U Required for transformation and DNA binding
HDLFAENC_01798 9.2e-153 cglB NU type II secretion system
HDLFAENC_01799 8.4e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDLFAENC_01800 1e-68 S cog cog4699
HDLFAENC_01801 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLFAENC_01802 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLFAENC_01803 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLFAENC_01804 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDLFAENC_01805 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDLFAENC_01806 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HDLFAENC_01807 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HDLFAENC_01808 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDLFAENC_01809 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
HDLFAENC_01810 1.4e-57 asp S cog cog1302
HDLFAENC_01811 8.4e-227 norM V Mate efflux family protein
HDLFAENC_01812 2.1e-277 thrC 4.2.3.1 E Threonine synthase
HDLFAENC_01813 7.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLFAENC_01814 1.4e-34 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
HDLFAENC_01815 2.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLFAENC_01816 2.6e-136 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLFAENC_01817 9.6e-65 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HDLFAENC_01818 0.0 pepO 3.4.24.71 O Peptidase family M13
HDLFAENC_01819 9.7e-39 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLFAENC_01820 5e-68 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLFAENC_01821 1.9e-64 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLFAENC_01822 2.9e-55 treB 2.7.1.201 G PTS System
HDLFAENC_01823 5.8e-21 treR K DNA-binding transcription factor activity
HDLFAENC_01824 1.3e-44 treR K trehalose operon
HDLFAENC_01825 3.3e-95 ywlG S Belongs to the UPF0340 family
HDLFAENC_01828 4.1e-33 L PFAM Integrase, catalytic core
HDLFAENC_01829 8e-96 L PFAM Integrase, catalytic core
HDLFAENC_01830 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HDLFAENC_01832 5.7e-109 6.3.2.2 H ergothioneine biosynthetic process
HDLFAENC_01833 2.7e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
HDLFAENC_01834 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HDLFAENC_01835 3.3e-09 L PFAM Integrase, catalytic core
HDLFAENC_01836 5.8e-94 L PFAM Integrase, catalytic core
HDLFAENC_01837 3.3e-62 rplQ J ribosomal protein l17
HDLFAENC_01838 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLFAENC_01839 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDLFAENC_01840 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDLFAENC_01841 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDLFAENC_01842 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDLFAENC_01843 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDLFAENC_01844 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDLFAENC_01845 7.4e-58 rplO J binds to the 23S rRNA
HDLFAENC_01846 2.5e-23 rpmD J ribosomal protein l30
HDLFAENC_01847 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDLFAENC_01848 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDLFAENC_01849 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDLFAENC_01850 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDLFAENC_01851 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDLFAENC_01852 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDLFAENC_01853 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDLFAENC_01854 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDLFAENC_01855 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDLFAENC_01856 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HDLFAENC_01857 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDLFAENC_01858 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDLFAENC_01859 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDLFAENC_01860 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDLFAENC_01861 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDLFAENC_01862 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDLFAENC_01863 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HDLFAENC_01864 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDLFAENC_01865 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HDLFAENC_01866 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDLFAENC_01867 0.0 XK27_09800 I Acyltransferase
HDLFAENC_01868 1.7e-35 XK27_09805 S MORN repeat protein
HDLFAENC_01869 3.5e-30 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDLFAENC_01870 8.8e-33 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDLFAENC_01871 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDLFAENC_01872 3.2e-26 adk 2.7.4.3 F topology modulation protein
HDLFAENC_01873 6.5e-37 adk 2.7.4.3 F topology modulation protein
HDLFAENC_01876 5.7e-222 L Transposase
HDLFAENC_01878 3.4e-155 Z012_04635 K sequence-specific DNA binding
HDLFAENC_01879 0.0 KLT serine threonine protein kinase
HDLFAENC_01880 3.6e-280 V ABC transporter
HDLFAENC_01882 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HDLFAENC_01883 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDLFAENC_01884 2.2e-44 yrzL S Belongs to the UPF0297 family
HDLFAENC_01885 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDLFAENC_01886 4.2e-44 yrzB S Belongs to the UPF0473 family
HDLFAENC_01887 3.5e-302 ccs S the current gene model (or a revised gene model) may contain a frame shift
HDLFAENC_01888 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDLFAENC_01889 7.5e-14
HDLFAENC_01890 3.4e-91 XK27_10930 K acetyltransferase
HDLFAENC_01891 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLFAENC_01892 5e-145 yaaA S Belongs to the UPF0246 family
HDLFAENC_01893 3.4e-169 XK27_01785 S cog cog1284
HDLFAENC_01894 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDLFAENC_01896 9.5e-223 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDLFAENC_01897 1.8e-136 metE 2.1.1.14 E Methionine synthase
HDLFAENC_01898 1.8e-30 metE 2.1.1.14 E Methionine synthase
HDLFAENC_01899 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDLFAENC_01900 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDLFAENC_01903 3.3e-45 yegS 2.7.1.107 I Diacylglycerol kinase
HDLFAENC_01904 1.6e-81 yegS 2.7.1.107 I Diacylglycerol kinase
HDLFAENC_01905 2.1e-95 S Hydrophobic domain protein
HDLFAENC_01907 1.3e-27 S Membrane
HDLFAENC_01908 2.4e-101
HDLFAENC_01909 1.8e-23 S Small integral membrane protein
HDLFAENC_01910 3.4e-84 M Protein conserved in bacteria
HDLFAENC_01911 1.1e-11 K CsbD-like
HDLFAENC_01912 1.9e-77 nudL L hydrolase
HDLFAENC_01913 3.4e-13 nudL L hydrolase
HDLFAENC_01914 8e-49 K transcriptional regulator, PadR family
HDLFAENC_01916 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
HDLFAENC_01917 5.5e-113 S Putative adhesin
HDLFAENC_01918 8.1e-159 XK27_06930 V domain protein
HDLFAENC_01919 6.4e-96 XK27_06935 K transcriptional regulator
HDLFAENC_01920 3.1e-54 ypaA S membrane
HDLFAENC_01921 2.7e-08
HDLFAENC_01922 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDLFAENC_01923 8.2e-48 veg S Biofilm formation stimulator VEG
HDLFAENC_01924 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDLFAENC_01925 3.9e-70 rplI J binds to the 23S rRNA
HDLFAENC_01926 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDLFAENC_01927 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDLFAENC_01928 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDLFAENC_01929 0.0 S Bacterial membrane protein, YfhO
HDLFAENC_01930 1.2e-90 isaA GH23 M Immunodominant staphylococcal antigen A
HDLFAENC_01931 3.1e-93 lytE M LysM domain protein
HDLFAENC_01932 1.4e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLFAENC_01933 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLFAENC_01934 4.4e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLFAENC_01935 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDLFAENC_01936 1.1e-137 ymfM S sequence-specific DNA binding
HDLFAENC_01937 4.5e-241 ymfH S Peptidase M16
HDLFAENC_01938 4.8e-235 ymfF S Peptidase M16
HDLFAENC_01939 1.6e-45 yaaA S S4 domain protein YaaA
HDLFAENC_01940 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDLFAENC_01941 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDLFAENC_01942 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HDLFAENC_01943 1.6e-152 yvjA S membrane
HDLFAENC_01944 6.7e-306 ybiT S abc transporter atp-binding protein
HDLFAENC_01945 0.0 XK27_10405 S Bacterial membrane protein YfhO
HDLFAENC_01949 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HDLFAENC_01950 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDLFAENC_01951 2.8e-195 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HDLFAENC_01952 8.5e-134 parB K Belongs to the ParB family
HDLFAENC_01953 4.9e-155 L Replication protein
HDLFAENC_01954 5.2e-64 hsp O Belongs to the small heat shock protein (HSP20) family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)