ORF_ID e_value Gene_name EC_number CAZy COGs Description
EDIJJJKJ_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EDIJJJKJ_00002 4.8e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EDIJJJKJ_00003 1.1e-29 yyzM S Protein conserved in bacteria
EDIJJJKJ_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EDIJJJKJ_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EDIJJJKJ_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EDIJJJKJ_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EDIJJJKJ_00008 2.1e-61 divIC D Septum formation initiator
EDIJJJKJ_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EDIJJJKJ_00011 3.8e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EDIJJJKJ_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EDIJJJKJ_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EDIJJJKJ_00014 1.6e-134 L Transposase
EDIJJJKJ_00015 1.1e-26 L transposase activity
EDIJJJKJ_00016 6e-28 L transposition
EDIJJJKJ_00017 2.7e-182 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_00030 5.3e-11
EDIJJJKJ_00036 1.7e-140 mreC M Involved in formation and maintenance of cell shape
EDIJJJKJ_00037 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EDIJJJKJ_00038 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
EDIJJJKJ_00039 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDIJJJKJ_00040 5e-27
EDIJJJKJ_00041 5.9e-219 araT 2.6.1.1 E Aminotransferase
EDIJJJKJ_00042 7e-144 recO L Involved in DNA repair and RecF pathway recombination
EDIJJJKJ_00043 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EDIJJJKJ_00044 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDIJJJKJ_00045 6.8e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EDIJJJKJ_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDIJJJKJ_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EDIJJJKJ_00048 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EDIJJJKJ_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EDIJJJKJ_00050 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EDIJJJKJ_00051 1.2e-79 L transposase activity
EDIJJJKJ_00052 1.7e-51 L transposition
EDIJJJKJ_00053 6.3e-34 L Integrase core domain protein
EDIJJJKJ_00054 1.4e-161 S CHAP domain
EDIJJJKJ_00055 2e-241 purD 6.3.4.13 F Belongs to the GARS family
EDIJJJKJ_00056 1.4e-75 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EDIJJJKJ_00057 5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EDIJJJKJ_00058 1.1e-141 1.1.1.169 H Ketopantoate reductase
EDIJJJKJ_00059 3.4e-24
EDIJJJKJ_00060 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EDIJJJKJ_00061 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_00062 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDIJJJKJ_00063 8.2e-70 argR K Regulates arginine biosynthesis genes
EDIJJJKJ_00064 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EDIJJJKJ_00065 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EDIJJJKJ_00066 5.7e-36 S Protein of unknown function (DUF3021)
EDIJJJKJ_00067 4.2e-62 KT phosphorelay signal transduction system
EDIJJJKJ_00069 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EDIJJJKJ_00071 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EDIJJJKJ_00072 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EDIJJJKJ_00073 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
EDIJJJKJ_00074 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EDIJJJKJ_00075 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EDIJJJKJ_00081 2.6e-10
EDIJJJKJ_00084 1.9e-07
EDIJJJKJ_00089 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDIJJJKJ_00090 3.9e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EDIJJJKJ_00091 5.5e-36 XK27_02060 S Transglycosylase associated protein
EDIJJJKJ_00092 6.9e-43 badR K DNA-binding transcription factor activity
EDIJJJKJ_00093 3.5e-97 S reductase
EDIJJJKJ_00094 5.9e-38 L transposition
EDIJJJKJ_00095 1.7e-41 L transposition
EDIJJJKJ_00097 3.8e-78 yocD 3.4.17.13 V carboxypeptidase activity
EDIJJJKJ_00098 1.4e-92 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EDIJJJKJ_00100 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
EDIJJJKJ_00101 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EDIJJJKJ_00102 1.1e-83 S Putative small multi-drug export protein
EDIJJJKJ_00103 6.2e-76 ctsR K Belongs to the CtsR family
EDIJJJKJ_00104 0.0 clpC O Belongs to the ClpA ClpB family
EDIJJJKJ_00105 1.3e-152 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDIJJJKJ_00106 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDIJJJKJ_00107 1.9e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDIJJJKJ_00108 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EDIJJJKJ_00109 5.3e-144 S SseB protein N-terminal domain
EDIJJJKJ_00110 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
EDIJJJKJ_00111 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDIJJJKJ_00112 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EDIJJJKJ_00115 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDIJJJKJ_00116 7e-92 yacP S RNA-binding protein containing a PIN domain
EDIJJJKJ_00117 3.4e-155 degV S DegV family
EDIJJJKJ_00119 4.2e-27 K helix-turn-helix
EDIJJJKJ_00120 1.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EDIJJJKJ_00121 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EDIJJJKJ_00122 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EDIJJJKJ_00123 4.1e-36 K sequence-specific DNA binding
EDIJJJKJ_00125 0.0 S Lantibiotic dehydratase, C terminus
EDIJJJKJ_00126 2.5e-231 spaC2 V Lanthionine synthetase C family protein
EDIJJJKJ_00127 9.1e-124 EGP Major facilitator Superfamily
EDIJJJKJ_00128 4.7e-36 EGP Major facilitator Superfamily
EDIJJJKJ_00129 6.3e-93 3.6.4.12 K Divergent AAA domain protein
EDIJJJKJ_00130 2.3e-226 int L Belongs to the 'phage' integrase family
EDIJJJKJ_00131 1.8e-38 S Helix-turn-helix domain
EDIJJJKJ_00133 9.4e-192
EDIJJJKJ_00135 8.8e-43 isp2 S pathogenesis
EDIJJJKJ_00136 3.8e-66 tnp L Transposase
EDIJJJKJ_00137 5.8e-48 tnp L Transposase
EDIJJJKJ_00138 2.1e-227 capA M Bacterial capsule synthesis protein
EDIJJJKJ_00139 3.6e-39 gcvR T UPF0237 protein
EDIJJJKJ_00140 1.7e-243 XK27_08635 S UPF0210 protein
EDIJJJKJ_00141 5.2e-77 ais G alpha-ribazole phosphatase activity
EDIJJJKJ_00142 4.7e-27 ais G alpha-ribazole phosphatase activity
EDIJJJKJ_00143 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EDIJJJKJ_00144 1.3e-102 acmA 3.2.1.17 NU amidase activity
EDIJJJKJ_00145 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EDIJJJKJ_00146 1.2e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EDIJJJKJ_00147 7.5e-298 dnaK O Heat shock 70 kDa protein
EDIJJJKJ_00148 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EDIJJJKJ_00149 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EDIJJJKJ_00150 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EDIJJJKJ_00151 1.6e-61 hmpT S membrane
EDIJJJKJ_00164 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EDIJJJKJ_00165 2.5e-169 L Transposase
EDIJJJKJ_00166 9.9e-19 S Domain of unknown function (DUF4649)
EDIJJJKJ_00167 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDIJJJKJ_00168 2.1e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EDIJJJKJ_00169 1.3e-87
EDIJJJKJ_00170 1.6e-77 sigH K DNA-templated transcription, initiation
EDIJJJKJ_00171 9.3e-150 ykuT M mechanosensitive ion channel
EDIJJJKJ_00172 7.3e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EDIJJJKJ_00173 6.3e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EDIJJJKJ_00174 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EDIJJJKJ_00175 5.8e-85 XK27_03960 S Protein of unknown function (DUF3013)
EDIJJJKJ_00176 1.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EDIJJJKJ_00177 1.8e-178 prmA J Ribosomal protein L11 methyltransferase
EDIJJJKJ_00178 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EDIJJJKJ_00179 1.1e-45 F nucleotide catabolic process
EDIJJJKJ_00180 1.1e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDIJJJKJ_00181 2.4e-141 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDIJJJKJ_00182 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDIJJJKJ_00183 1.8e-83 nrdI F Belongs to the NrdI family
EDIJJJKJ_00184 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EDIJJJKJ_00185 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EDIJJJKJ_00186 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDIJJJKJ_00187 4e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDIJJJKJ_00188 1.2e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDIJJJKJ_00189 3.9e-41 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDIJJJKJ_00190 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EDIJJJKJ_00191 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EDIJJJKJ_00192 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EDIJJJKJ_00193 1.6e-200 yhjX P Major Facilitator
EDIJJJKJ_00194 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EDIJJJKJ_00195 5e-94 V VanZ like family
EDIJJJKJ_00198 1e-123 glnQ E abc transporter atp-binding protein
EDIJJJKJ_00199 1.5e-275 glnP P ABC transporter
EDIJJJKJ_00200 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EDIJJJKJ_00201 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EDIJJJKJ_00202 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
EDIJJJKJ_00203 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EDIJJJKJ_00204 1.4e-234 sufD O assembly protein SufD
EDIJJJKJ_00205 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EDIJJJKJ_00206 8.6e-75 nifU C SUF system FeS assembly protein, NifU family
EDIJJJKJ_00207 5.9e-274 sufB O assembly protein SufB
EDIJJJKJ_00208 2.4e-19 oppA E ABC transporter substrate-binding protein
EDIJJJKJ_00209 1.9e-158 oppA E ABC transporter substrate-binding protein
EDIJJJKJ_00210 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDIJJJKJ_00211 8.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDIJJJKJ_00212 7.9e-76 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDIJJJKJ_00213 3.1e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDIJJJKJ_00214 6.1e-28 oppD P Belongs to the ABC transporter superfamily
EDIJJJKJ_00215 6.5e-33 oppD P Belongs to the ABC transporter superfamily
EDIJJJKJ_00216 1.8e-69 oppD P Belongs to the ABC transporter superfamily
EDIJJJKJ_00217 3.9e-46 oppD P Belongs to the ABC transporter superfamily
EDIJJJKJ_00218 3.9e-165 oppF P Belongs to the ABC transporter superfamily
EDIJJJKJ_00221 6.6e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EDIJJJKJ_00222 1.6e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDIJJJKJ_00223 6e-128 K sequence-specific DNA binding
EDIJJJKJ_00224 0.0 KLT serine threonine protein kinase
EDIJJJKJ_00225 1.9e-223 EGP Major facilitator Superfamily
EDIJJJKJ_00226 3.1e-72 adcR K transcriptional
EDIJJJKJ_00227 1.3e-136 adcC P ABC transporter, ATP-binding protein
EDIJJJKJ_00228 1.4e-131 adcB P ABC transporter (Permease
EDIJJJKJ_00229 1.3e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EDIJJJKJ_00230 1e-66 ptsG 2.7.1.199, 2.7.1.208 G pts system
EDIJJJKJ_00231 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
EDIJJJKJ_00232 1.4e-154 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
EDIJJJKJ_00233 8.5e-108 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EDIJJJKJ_00234 2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EDIJJJKJ_00235 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
EDIJJJKJ_00236 1.9e-127 yeeN K transcriptional regulatory protein
EDIJJJKJ_00237 9.8e-50 yajC U protein transport
EDIJJJKJ_00238 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EDIJJJKJ_00239 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
EDIJJJKJ_00240 1.9e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EDIJJJKJ_00241 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EDIJJJKJ_00242 0.0 WQ51_06230 S ABC transporter substrate binding protein
EDIJJJKJ_00243 5.2e-142 cmpC S abc transporter atp-binding protein
EDIJJJKJ_00244 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EDIJJJKJ_00245 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EDIJJJKJ_00246 1e-57 L transposase activity
EDIJJJKJ_00247 4.7e-61 L transposition
EDIJJJKJ_00248 4.8e-34 L Integrase core domain protein
EDIJJJKJ_00251 4e-42
EDIJJJKJ_00252 2.7e-28 J TM2 domain
EDIJJJKJ_00253 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDIJJJKJ_00254 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDIJJJKJ_00255 7.4e-25 secE U Belongs to the SecE SEC61-gamma family
EDIJJJKJ_00256 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EDIJJJKJ_00257 2.7e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EDIJJJKJ_00258 7e-56 cof Q phosphatase activity
EDIJJJKJ_00259 3.3e-36 cof Q phosphatase activity
EDIJJJKJ_00260 5.6e-138 glcR K transcriptional regulator (DeoR family)
EDIJJJKJ_00261 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDIJJJKJ_00262 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_00263 1.7e-93 S thiolester hydrolase activity
EDIJJJKJ_00264 8.1e-145 S COG1073 Hydrolases of the alpha beta superfamily
EDIJJJKJ_00265 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EDIJJJKJ_00266 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EDIJJJKJ_00267 3.2e-77 yhaI L Membrane
EDIJJJKJ_00268 6e-260 pepC 3.4.22.40 E aminopeptidase
EDIJJJKJ_00269 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDIJJJKJ_00270 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EDIJJJKJ_00271 3.1e-95 ypsA S Belongs to the UPF0398 family
EDIJJJKJ_00272 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EDIJJJKJ_00273 5.1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EDIJJJKJ_00274 0.0 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EDIJJJKJ_00275 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EDIJJJKJ_00276 2.5e-23
EDIJJJKJ_00277 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EDIJJJKJ_00278 8.4e-84 XK27_09675 K -acetyltransferase
EDIJJJKJ_00279 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EDIJJJKJ_00280 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EDIJJJKJ_00281 1e-59 L Integrase core domain protein
EDIJJJKJ_00282 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDIJJJKJ_00283 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EDIJJJKJ_00284 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDIJJJKJ_00285 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EDIJJJKJ_00286 5.2e-98 ybhL S Belongs to the BI1 family
EDIJJJKJ_00289 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EDIJJJKJ_00290 2.8e-91 K transcriptional regulator
EDIJJJKJ_00291 7.6e-36 yneF S UPF0154 protein
EDIJJJKJ_00292 2.2e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EDIJJJKJ_00293 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EDIJJJKJ_00294 3.5e-99 XK27_09740 S Phosphoesterase
EDIJJJKJ_00295 4.1e-86 ykuL S CBS domain
EDIJJJKJ_00296 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EDIJJJKJ_00297 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EDIJJJKJ_00298 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EDIJJJKJ_00299 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDIJJJKJ_00300 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EDIJJJKJ_00301 1.2e-258 trkH P Cation transport protein
EDIJJJKJ_00302 1.8e-248 trkA P Potassium transporter peripheral membrane component
EDIJJJKJ_00303 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EDIJJJKJ_00304 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EDIJJJKJ_00305 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EDIJJJKJ_00306 1.5e-161 K sequence-specific DNA binding
EDIJJJKJ_00307 1.9e-33 V protein secretion by the type I secretion system
EDIJJJKJ_00308 1.6e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDIJJJKJ_00309 2e-36 V protein secretion by the type I secretion system
EDIJJJKJ_00310 2.1e-64 comA V protein secretion by the type I secretion system
EDIJJJKJ_00311 1.4e-69 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDIJJJKJ_00312 3.7e-51 yhaI L Membrane
EDIJJJKJ_00313 4.7e-105 S Domain of unknown function (DUF4173)
EDIJJJKJ_00314 6.8e-95 ureI S AmiS/UreI family transporter
EDIJJJKJ_00315 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EDIJJJKJ_00316 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EDIJJJKJ_00317 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EDIJJJKJ_00318 6.6e-78 ureE O enzyme active site formation
EDIJJJKJ_00319 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EDIJJJKJ_00320 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EDIJJJKJ_00321 1.5e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EDIJJJKJ_00322 1.8e-176 cbiM P PDGLE domain
EDIJJJKJ_00323 2.9e-137 P cobalt transport protein
EDIJJJKJ_00324 1.6e-131 cbiO P ABC transporter
EDIJJJKJ_00325 6.9e-153 ET amino acid transport
EDIJJJKJ_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDIJJJKJ_00327 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
EDIJJJKJ_00328 3.8e-205 EGP Transmembrane secretion effector
EDIJJJKJ_00329 1.8e-153 ET amino acid transport
EDIJJJKJ_00330 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
EDIJJJKJ_00331 1e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EDIJJJKJ_00332 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EDIJJJKJ_00333 9e-65 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EDIJJJKJ_00334 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EDIJJJKJ_00335 3e-98 metI P ABC transporter (Permease
EDIJJJKJ_00336 2.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EDIJJJKJ_00337 5.2e-33 salL 2.5.1.63, 2.5.1.94 F Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
EDIJJJKJ_00338 2.6e-109 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EDIJJJKJ_00339 5.3e-27 P Psort location CytoplasmicMembrane, score
EDIJJJKJ_00340 1.2e-36 P Psort location CytoplasmicMembrane, score
EDIJJJKJ_00341 2.8e-38 ykoD P ATPase activity
EDIJJJKJ_00342 5e-265 ykoD P abc transporter atp-binding protein
EDIJJJKJ_00343 9.4e-12 cbiQ P cobalt transport
EDIJJJKJ_00344 3e-93 cbiQ P cobalt transport
EDIJJJKJ_00345 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EDIJJJKJ_00346 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
EDIJJJKJ_00347 3.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
EDIJJJKJ_00348 1.2e-242 P COG0168 Trk-type K transport systems, membrane components
EDIJJJKJ_00349 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EDIJJJKJ_00350 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
EDIJJJKJ_00351 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDIJJJKJ_00352 2.8e-282 T PhoQ Sensor
EDIJJJKJ_00353 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EDIJJJKJ_00354 1.3e-218 dnaB L Replication initiation and membrane attachment
EDIJJJKJ_00355 4e-167 dnaI L Primosomal protein DnaI
EDIJJJKJ_00356 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EDIJJJKJ_00357 3.5e-283 P ABC transporter transmembrane region
EDIJJJKJ_00359 1e-223 L Transposase
EDIJJJKJ_00360 9.8e-25 S Protein of unknown function DUF262
EDIJJJKJ_00361 4.6e-233 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EDIJJJKJ_00362 5e-63 manO S protein conserved in bacteria
EDIJJJKJ_00363 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
EDIJJJKJ_00364 2.7e-117 manM G pts system
EDIJJJKJ_00365 7.5e-183 manL 2.7.1.191 G pts system
EDIJJJKJ_00366 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EDIJJJKJ_00367 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EDIJJJKJ_00368 1.5e-248 pbuO S permease
EDIJJJKJ_00369 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EDIJJJKJ_00370 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
EDIJJJKJ_00371 2.5e-220 brpA K Transcriptional
EDIJJJKJ_00372 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EDIJJJKJ_00373 4.1e-212 nusA K Participates in both transcription termination and antitermination
EDIJJJKJ_00374 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EDIJJJKJ_00375 3.9e-41 ylxQ J ribosomal protein
EDIJJJKJ_00376 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EDIJJJKJ_00377 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EDIJJJKJ_00378 2.1e-48 yvdD 3.2.2.10 S cytokinin biosynthetic process
EDIJJJKJ_00379 4e-26 yvdD 3.2.2.10 S cytokinin biosynthetic process
EDIJJJKJ_00380 1.5e-233 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EDIJJJKJ_00381 4.6e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EDIJJJKJ_00382 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EDIJJJKJ_00383 1.4e-74 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EDIJJJKJ_00384 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
EDIJJJKJ_00385 2.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EDIJJJKJ_00387 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EDIJJJKJ_00388 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EDIJJJKJ_00389 1.2e-74 ylbF S Belongs to the UPF0342 family
EDIJJJKJ_00390 7.1e-46 ylbG S UPF0298 protein
EDIJJJKJ_00391 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EDIJJJKJ_00392 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
EDIJJJKJ_00393 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
EDIJJJKJ_00394 1.3e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EDIJJJKJ_00395 1.8e-122 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EDIJJJKJ_00396 1.5e-71 acuB S IMP dehydrogenase activity
EDIJJJKJ_00397 3.3e-43 acuB S IMP dehydrogenase activity
EDIJJJKJ_00398 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EDIJJJKJ_00399 1.1e-110 yvyE 3.4.13.9 S YigZ family
EDIJJJKJ_00400 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EDIJJJKJ_00401 3.4e-123 comFC S Competence protein
EDIJJJKJ_00402 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EDIJJJKJ_00410 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
EDIJJJKJ_00411 6.4e-108 S Domain of unknown function (DUF1803)
EDIJJJKJ_00412 7.8e-102 ygaC J Belongs to the UPF0374 family
EDIJJJKJ_00413 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
EDIJJJKJ_00414 2.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDIJJJKJ_00415 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
EDIJJJKJ_00416 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
EDIJJJKJ_00417 5.6e-115 S Haloacid dehalogenase-like hydrolase
EDIJJJKJ_00418 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EDIJJJKJ_00419 1.4e-72 marR K Transcriptional regulator, MarR family
EDIJJJKJ_00420 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EDIJJJKJ_00421 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDIJJJKJ_00422 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EDIJJJKJ_00423 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EDIJJJKJ_00424 1.3e-126 IQ reductase
EDIJJJKJ_00425 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EDIJJJKJ_00426 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EDIJJJKJ_00427 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EDIJJJKJ_00428 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EDIJJJKJ_00429 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EDIJJJKJ_00430 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EDIJJJKJ_00431 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EDIJJJKJ_00432 3.6e-128 tnp L Transposase
EDIJJJKJ_00433 9.2e-207 rny D Endoribonuclease that initiates mRNA decay
EDIJJJKJ_00434 1.2e-85 L Transposase
EDIJJJKJ_00435 5.6e-114 fruR K transcriptional
EDIJJJKJ_00436 3.4e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EDIJJJKJ_00437 3.3e-124 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
EDIJJJKJ_00438 1.8e-79 fruA 2.7.1.202 G phosphotransferase system
EDIJJJKJ_00439 2.9e-52 fruA 2.7.1.202 G phosphotransferase system
EDIJJJKJ_00440 3.8e-48 fruA 2.7.1.202 G phosphotransferase system
EDIJJJKJ_00441 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDIJJJKJ_00442 2.8e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDIJJJKJ_00444 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EDIJJJKJ_00445 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDIJJJKJ_00446 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EDIJJJKJ_00447 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EDIJJJKJ_00448 1.1e-38 2.3.1.128 K acetyltransferase
EDIJJJKJ_00449 6.4e-29 2.3.1.128 K acetyltransferase
EDIJJJKJ_00450 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EDIJJJKJ_00451 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EDIJJJKJ_00452 2.1e-99 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDIJJJKJ_00453 1.3e-37 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDIJJJKJ_00454 2.6e-64 WQ51_03320 S cog cog4835
EDIJJJKJ_00455 2.9e-31 XK27_08360 S lipid binding
EDIJJJKJ_00456 3.4e-109 XK27_08360 T EDD domain protein, DegV family
EDIJJJKJ_00457 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EDIJJJKJ_00458 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EDIJJJKJ_00459 0.0 yfmR S abc transporter atp-binding protein
EDIJJJKJ_00460 1.6e-24 U response to pH
EDIJJJKJ_00461 1.4e-136 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EDIJJJKJ_00462 2.2e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EDIJJJKJ_00463 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EDIJJJKJ_00464 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EDIJJJKJ_00466 1.9e-77 K DNA-binding transcription factor activity
EDIJJJKJ_00467 0.0 lmrA1 V abc transporter atp-binding protein
EDIJJJKJ_00468 0.0 lmrA2 V abc transporter atp-binding protein
EDIJJJKJ_00469 2.3e-122 sptS 2.7.13.3 T Histidine kinase
EDIJJJKJ_00470 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EDIJJJKJ_00471 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EDIJJJKJ_00472 5.3e-161 cvfB S Protein conserved in bacteria
EDIJJJKJ_00473 7.4e-35 yozE S Belongs to the UPF0346 family
EDIJJJKJ_00474 2.8e-122 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
EDIJJJKJ_00475 1.9e-13
EDIJJJKJ_00476 9e-184 L Transposase
EDIJJJKJ_00477 1.4e-61 rlpA M LysM domain protein
EDIJJJKJ_00478 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
EDIJJJKJ_00482 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EDIJJJKJ_00483 3.7e-165 K transcriptional regulator (lysR family)
EDIJJJKJ_00484 1.4e-186 coiA 3.6.4.12 S Competence protein
EDIJJJKJ_00485 0.0 pepF E oligoendopeptidase F
EDIJJJKJ_00486 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
EDIJJJKJ_00487 1.2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EDIJJJKJ_00488 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EDIJJJKJ_00489 4.6e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDIJJJKJ_00490 1.7e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDIJJJKJ_00491 2e-42 S pathogenesis
EDIJJJKJ_00492 1.5e-132 3.4.17.14, 3.5.1.28 NU amidase activity
EDIJJJKJ_00493 5.3e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EDIJJJKJ_00494 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EDIJJJKJ_00495 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EDIJJJKJ_00496 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EDIJJJKJ_00497 1.8e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EDIJJJKJ_00498 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EDIJJJKJ_00499 5.5e-141 yxkH G deacetylase
EDIJJJKJ_00500 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EDIJJJKJ_00501 3.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EDIJJJKJ_00502 2.1e-152 rarD S Transporter
EDIJJJKJ_00503 2.2e-15 T peptidase
EDIJJJKJ_00504 8.9e-14 coiA 3.6.4.12 S Competence protein
EDIJJJKJ_00505 2.3e-53 S FMN binding
EDIJJJKJ_00506 2.7e-54 S FMN binding
EDIJJJKJ_00507 1.2e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDIJJJKJ_00508 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EDIJJJKJ_00509 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDIJJJKJ_00510 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
EDIJJJKJ_00511 3.3e-78 atpF C ATP synthase F(0) sector subunit b
EDIJJJKJ_00512 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDIJJJKJ_00513 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EDIJJJKJ_00514 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EDIJJJKJ_00515 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EDIJJJKJ_00516 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EDIJJJKJ_00517 8.1e-230 ftsW D Belongs to the SEDS family
EDIJJJKJ_00518 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EDIJJJKJ_00519 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EDIJJJKJ_00520 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EDIJJJKJ_00521 6.4e-162 holB 2.7.7.7 L dna polymerase iii
EDIJJJKJ_00522 1.2e-135 yaaT S stage 0 sporulation protein
EDIJJJKJ_00523 9.5e-55 yabA L Involved in initiation control of chromosome replication
EDIJJJKJ_00524 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EDIJJJKJ_00525 1.7e-232 amt P Ammonium Transporter
EDIJJJKJ_00526 6.6e-54 glnB K Belongs to the P(II) protein family
EDIJJJKJ_00527 3.2e-105 mur1 NU mannosyl-glycoprotein
EDIJJJKJ_00528 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EDIJJJKJ_00529 1.3e-32 nptA P sodium-dependent phosphate transmembrane transporter activity
EDIJJJKJ_00530 3.2e-85 nptA P COG1283 Na phosphate symporter
EDIJJJKJ_00531 2.3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EDIJJJKJ_00532 7.4e-55
EDIJJJKJ_00533 2.8e-25
EDIJJJKJ_00534 7.8e-61
EDIJJJKJ_00535 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EDIJJJKJ_00536 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EDIJJJKJ_00537 4.5e-39 ynzC S UPF0291 protein
EDIJJJKJ_00538 2.5e-253 cycA E permease
EDIJJJKJ_00539 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
EDIJJJKJ_00540 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EDIJJJKJ_00541 5.8e-71 pts33BCA G pts system
EDIJJJKJ_00542 9e-96 pts33BCA G pts system
EDIJJJKJ_00543 2e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
EDIJJJKJ_00544 6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDIJJJKJ_00549 1.2e-166 fhuR K transcriptional regulator (lysR family)
EDIJJJKJ_00550 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EDIJJJKJ_00551 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDIJJJKJ_00552 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EDIJJJKJ_00553 3.7e-227 pyrP F uracil Permease
EDIJJJKJ_00554 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EDIJJJKJ_00555 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EDIJJJKJ_00556 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EDIJJJKJ_00557 1.7e-134 J Putative SAM-dependent methyltransferase
EDIJJJKJ_00558 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDIJJJKJ_00559 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDIJJJKJ_00560 3.8e-43 V permease protein
EDIJJJKJ_00561 8.3e-35 V permease protein
EDIJJJKJ_00562 3.7e-22 V efflux transmembrane transporter activity
EDIJJJKJ_00563 7e-27 ytrF V efflux transmembrane transporter activity
EDIJJJKJ_00564 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EDIJJJKJ_00565 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EDIJJJKJ_00567 0.0 mdlB V abc transporter atp-binding protein
EDIJJJKJ_00568 0.0 lmrA V abc transporter atp-binding protein
EDIJJJKJ_00569 1.8e-195 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EDIJJJKJ_00570 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EDIJJJKJ_00571 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EDIJJJKJ_00572 1.9e-132 rr02 KT response regulator
EDIJJJKJ_00573 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EDIJJJKJ_00574 1.8e-167 V ABC transporter
EDIJJJKJ_00575 5.4e-122 sagI S ABC-2 type transporter
EDIJJJKJ_00576 6.9e-197 yceA S Belongs to the UPF0176 family
EDIJJJKJ_00577 1.9e-29 XK27_00085 K Transcriptional
EDIJJJKJ_00578 4.3e-22
EDIJJJKJ_00579 9.1e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
EDIJJJKJ_00580 6.6e-114 S VIT family
EDIJJJKJ_00581 1.1e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDIJJJKJ_00582 3e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDIJJJKJ_00583 1.2e-17 ald 1.4.1.1 E alanine dehydrogenase activity
EDIJJJKJ_00584 3.6e-45 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EDIJJJKJ_00585 3.6e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDIJJJKJ_00586 4.6e-105 GBS0088 J protein conserved in bacteria
EDIJJJKJ_00587 3e-143 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EDIJJJKJ_00588 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EDIJJJKJ_00589 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
EDIJJJKJ_00590 5.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EDIJJJKJ_00591 3.9e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EDIJJJKJ_00592 4.5e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EDIJJJKJ_00593 6.4e-17
EDIJJJKJ_00594 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EDIJJJKJ_00596 3.5e-07 U protein secretion
EDIJJJKJ_00597 5.5e-51 U protein secretion
EDIJJJKJ_00599 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EDIJJJKJ_00600 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EDIJJJKJ_00601 3.2e-20 XK27_13030
EDIJJJKJ_00602 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EDIJJJKJ_00603 7.4e-172 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EDIJJJKJ_00604 7.3e-166 S Protein of unknown function (DUF3114)
EDIJJJKJ_00605 3.6e-22 S Protein of unknown function (DUF3114)
EDIJJJKJ_00606 3.6e-120 yqfA K protein, Hemolysin III
EDIJJJKJ_00607 1.6e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EDIJJJKJ_00608 1.7e-218 mvaS 2.3.3.10 I synthase
EDIJJJKJ_00609 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EDIJJJKJ_00610 4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EDIJJJKJ_00611 9.7e-22
EDIJJJKJ_00612 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EDIJJJKJ_00613 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EDIJJJKJ_00614 8.9e-251 mmuP E amino acid
EDIJJJKJ_00615 3.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EDIJJJKJ_00616 1.4e-29 S Domain of unknown function (DUF1912)
EDIJJJKJ_00617 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
EDIJJJKJ_00618 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EDIJJJKJ_00619 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDIJJJKJ_00620 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDIJJJKJ_00621 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
EDIJJJKJ_00622 4.8e-16 S Protein of unknown function (DUF2969)
EDIJJJKJ_00625 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
EDIJJJKJ_00628 7.8e-30 S Domain of Unknown Function with PDB structure (DUF3862)
EDIJJJKJ_00629 1.1e-30 S Domain of Unknown Function with PDB structure (DUF3862)
EDIJJJKJ_00630 5.7e-71 M Pfam SNARE associated Golgi protein
EDIJJJKJ_00631 4e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
EDIJJJKJ_00632 7.8e-08 S oxidoreductase
EDIJJJKJ_00633 7e-26 2.7.7.15 S inositol 2-dehydrogenase activity
EDIJJJKJ_00634 1.4e-50 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
EDIJJJKJ_00635 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
EDIJJJKJ_00636 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EDIJJJKJ_00637 0.0 clpE O Belongs to the ClpA ClpB family
EDIJJJKJ_00638 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EDIJJJKJ_00639 1.3e-34 ykuJ S protein conserved in bacteria
EDIJJJKJ_00640 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EDIJJJKJ_00641 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_00642 1.1e-78 feoA P FeoA domain protein
EDIJJJKJ_00643 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EDIJJJKJ_00644 6.6e-08
EDIJJJKJ_00645 1.5e-35 yugF I carboxylic ester hydrolase activity
EDIJJJKJ_00646 1.5e-23 I Alpha/beta hydrolase family
EDIJJJKJ_00647 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EDIJJJKJ_00648 1.2e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EDIJJJKJ_00649 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EDIJJJKJ_00650 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EDIJJJKJ_00651 5.8e-64 licT K transcriptional antiterminator
EDIJJJKJ_00652 6.8e-53 licT K transcriptional antiterminator
EDIJJJKJ_00653 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EDIJJJKJ_00654 5.8e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EDIJJJKJ_00655 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EDIJJJKJ_00656 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EDIJJJKJ_00657 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EDIJJJKJ_00658 2.9e-221 mdtG EGP Major facilitator Superfamily
EDIJJJKJ_00659 2e-33 secG U Preprotein translocase subunit SecG
EDIJJJKJ_00660 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EDIJJJKJ_00661 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EDIJJJKJ_00662 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDIJJJKJ_00663 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EDIJJJKJ_00664 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EDIJJJKJ_00665 3.4e-183 ccpA K Catabolite control protein A
EDIJJJKJ_00666 4e-27 yyaQ S YjbR
EDIJJJKJ_00667 7.4e-146 yyaQ S YjbR
EDIJJJKJ_00668 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EDIJJJKJ_00669 1.3e-78 yueI S Protein of unknown function (DUF1694)
EDIJJJKJ_00670 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EDIJJJKJ_00671 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EDIJJJKJ_00672 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
EDIJJJKJ_00673 2.9e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EDIJJJKJ_00674 3.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDIJJJKJ_00675 4.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EDIJJJKJ_00676 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EDIJJJKJ_00677 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EDIJJJKJ_00678 3.2e-53 yheA S Belongs to the UPF0342 family
EDIJJJKJ_00679 1.1e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EDIJJJKJ_00680 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EDIJJJKJ_00681 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EDIJJJKJ_00682 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
EDIJJJKJ_00683 1.1e-59 msrR K Transcriptional regulator
EDIJJJKJ_00684 7.7e-177 msrR K Transcriptional regulator
EDIJJJKJ_00685 2.9e-160 ydiA P C4-dicarboxylate transporter malic acid transport
EDIJJJKJ_00686 4.8e-204 I acyl-CoA dehydrogenase
EDIJJJKJ_00687 7.7e-97 mip S hydroperoxide reductase activity
EDIJJJKJ_00688 5.9e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDIJJJKJ_00689 1.6e-84
EDIJJJKJ_00690 1e-31 K Cro/C1-type HTH DNA-binding domain
EDIJJJKJ_00691 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EDIJJJKJ_00692 2.4e-28 estA E GDSL-like Lipase/Acylhydrolase
EDIJJJKJ_00693 1.8e-94
EDIJJJKJ_00694 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EDIJJJKJ_00695 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDIJJJKJ_00696 2.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDIJJJKJ_00697 1.9e-189 S CRISPR-associated protein Csn2 subfamily St
EDIJJJKJ_00698 3.4e-149 ycgQ S TIGR03943 family
EDIJJJKJ_00699 3.4e-158 XK27_03015 S permease
EDIJJJKJ_00701 0.0 yhgF K Transcriptional accessory protein
EDIJJJKJ_00702 4.9e-86 ydcK S Belongs to the SprT family
EDIJJJKJ_00703 2.9e-41 pspC KT PspC domain
EDIJJJKJ_00704 3.1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EDIJJJKJ_00705 1.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EDIJJJKJ_00707 1e-67 ytxH S General stress protein
EDIJJJKJ_00709 3e-178 yegQ O Peptidase U32
EDIJJJKJ_00710 3.4e-252 yegQ O Peptidase U32
EDIJJJKJ_00711 5.8e-89 bioY S biotin synthase
EDIJJJKJ_00713 1.1e-33 XK27_12190 S protein conserved in bacteria
EDIJJJKJ_00714 2.7e-236 mntH P H( )-stimulated, divalent metal cation uptake system
EDIJJJKJ_00715 2.4e-10
EDIJJJKJ_00716 7e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
EDIJJJKJ_00717 0.0 L helicase
EDIJJJKJ_00718 1.3e-131 L PLD-like domain
EDIJJJKJ_00719 5.8e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EDIJJJKJ_00720 1.9e-15 M LysM domain
EDIJJJKJ_00721 9.7e-61 M LysM domain
EDIJJJKJ_00722 1.9e-58 M LysM domain
EDIJJJKJ_00723 7.6e-16
EDIJJJKJ_00724 2.3e-175 S hydrolase
EDIJJJKJ_00725 8.7e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EDIJJJKJ_00726 2.3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EDIJJJKJ_00727 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EDIJJJKJ_00728 6e-27 P Hemerythrin HHE cation binding domain protein
EDIJJJKJ_00729 3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EDIJJJKJ_00730 1.2e-135 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDIJJJKJ_00731 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
EDIJJJKJ_00732 5.8e-270 hsdM 2.1.1.72 V N-6 DNA Methylase
EDIJJJKJ_00733 1.9e-220 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
EDIJJJKJ_00734 3.2e-183 prrC S AAA domain
EDIJJJKJ_00735 7.9e-29 S PD-(D/E)XK nuclease family transposase
EDIJJJKJ_00736 7.8e-48 S double-stranded DNA endodeoxyribonuclease activity
EDIJJJKJ_00737 1.1e-173 spd F DNA RNA non-specific endonuclease
EDIJJJKJ_00738 3.4e-92 lemA S LemA family
EDIJJJKJ_00739 6.4e-133 htpX O Belongs to the peptidase M48B family
EDIJJJKJ_00740 4.2e-75 S Psort location CytoplasmicMembrane, score
EDIJJJKJ_00741 6.2e-56 S Domain of unknown function (DUF4430)
EDIJJJKJ_00742 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EDIJJJKJ_00743 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EDIJJJKJ_00744 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EDIJJJKJ_00745 2.5e-197 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EDIJJJKJ_00746 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EDIJJJKJ_00747 3.1e-79 dps P Belongs to the Dps family
EDIJJJKJ_00748 1.1e-80 perR P Belongs to the Fur family
EDIJJJKJ_00749 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_00750 8.4e-28 yqgQ S protein conserved in bacteria
EDIJJJKJ_00751 2.2e-179 glk 2.7.1.2 G Glucokinase
EDIJJJKJ_00752 0.0 typA T GTP-binding protein TypA
EDIJJJKJ_00754 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EDIJJJKJ_00755 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EDIJJJKJ_00756 2.2e-178 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EDIJJJKJ_00757 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EDIJJJKJ_00758 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EDIJJJKJ_00759 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EDIJJJKJ_00760 2.3e-96 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EDIJJJKJ_00761 8.8e-35 yggT D integral membrane protein
EDIJJJKJ_00762 7.2e-144 ylmH T S4 RNA-binding domain
EDIJJJKJ_00763 7.9e-136 divIVA D Cell division protein DivIVA
EDIJJJKJ_00764 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EDIJJJKJ_00765 1.2e-17
EDIJJJKJ_00766 8.4e-10
EDIJJJKJ_00767 2e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
EDIJJJKJ_00768 2e-45 rpmE2 J 50S ribosomal protein L31
EDIJJJKJ_00769 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDIJJJKJ_00770 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EDIJJJKJ_00771 2e-154 gst O Glutathione S-transferase
EDIJJJKJ_00772 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EDIJJJKJ_00773 2.4e-112 tdk 2.7.1.21 F thymidine kinase
EDIJJJKJ_00774 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EDIJJJKJ_00775 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EDIJJJKJ_00776 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EDIJJJKJ_00777 1.4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EDIJJJKJ_00778 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
EDIJJJKJ_00779 2.4e-107 pvaA M lytic transglycosylase activity
EDIJJJKJ_00780 0.0 yfiB1 V abc transporter atp-binding protein
EDIJJJKJ_00781 0.0 XK27_10035 V abc transporter atp-binding protein
EDIJJJKJ_00782 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
EDIJJJKJ_00783 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDIJJJKJ_00784 4.6e-238 dltB M Membrane protein involved in D-alanine export
EDIJJJKJ_00785 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDIJJJKJ_00786 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EDIJJJKJ_00787 6.3e-34 L Integrase core domain protein
EDIJJJKJ_00788 3.6e-31 L Integrase core domain protein
EDIJJJKJ_00789 9.3e-53 L transposition
EDIJJJKJ_00790 3.4e-19 L transposase activity
EDIJJJKJ_00791 0.0 3.6.3.8 P cation transport ATPase
EDIJJJKJ_00792 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EDIJJJKJ_00794 2.9e-12
EDIJJJKJ_00796 4.8e-282 S DNA primase
EDIJJJKJ_00797 5.6e-142 KL Phage plasmid primase P4 family
EDIJJJKJ_00798 3.1e-22
EDIJJJKJ_00802 1.8e-19 K Cro/C1-type HTH DNA-binding domain
EDIJJJKJ_00803 4.8e-32 xre K transcriptional
EDIJJJKJ_00804 4.5e-219 sip L Belongs to the 'phage' integrase family
EDIJJJKJ_00806 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EDIJJJKJ_00807 7.3e-166 metF 1.5.1.20 C reductase
EDIJJJKJ_00808 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EDIJJJKJ_00809 1.7e-94 panT S ECF transporter, substrate-specific component
EDIJJJKJ_00810 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EDIJJJKJ_00811 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EDIJJJKJ_00812 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EDIJJJKJ_00813 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDIJJJKJ_00814 2.8e-40 T PhoQ Sensor
EDIJJJKJ_00815 1.7e-43 T PhoQ Sensor
EDIJJJKJ_00816 1.9e-127 T PhoQ Sensor
EDIJJJKJ_00817 1.2e-165 L integrase core domain
EDIJJJKJ_00818 3.9e-122 L Transposase
EDIJJJKJ_00819 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
EDIJJJKJ_00820 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
EDIJJJKJ_00821 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EDIJJJKJ_00822 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EDIJJJKJ_00823 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EDIJJJKJ_00824 8.6e-65 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EDIJJJKJ_00825 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EDIJJJKJ_00826 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EDIJJJKJ_00827 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EDIJJJKJ_00828 7.3e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EDIJJJKJ_00829 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EDIJJJKJ_00830 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
EDIJJJKJ_00831 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
EDIJJJKJ_00832 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EDIJJJKJ_00833 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EDIJJJKJ_00834 6.8e-81 ypmB S Protein conserved in bacteria
EDIJJJKJ_00835 1.9e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EDIJJJKJ_00836 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDIJJJKJ_00838 8.1e-08
EDIJJJKJ_00839 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EDIJJJKJ_00840 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EDIJJJKJ_00841 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
EDIJJJKJ_00842 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EDIJJJKJ_00843 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EDIJJJKJ_00844 7.7e-20 D nuclear chromosome segregation
EDIJJJKJ_00845 7.4e-138 yejC S cyclic nucleotide-binding protein
EDIJJJKJ_00846 1.2e-163 rapZ S Displays ATPase and GTPase activities
EDIJJJKJ_00847 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EDIJJJKJ_00848 8.7e-162 whiA K May be required for sporulation
EDIJJJKJ_00849 2.8e-90 pepD E Dipeptidase
EDIJJJKJ_00850 5.8e-41 pepD E dipeptidase activity
EDIJJJKJ_00851 5.4e-32 cspD K Cold shock protein domain
EDIJJJKJ_00852 9.4e-43 K Cold-Shock Protein
EDIJJJKJ_00853 1e-223 L Transposase
EDIJJJKJ_00854 0.0 copB 3.6.3.4 P P-type ATPase
EDIJJJKJ_00855 8.5e-218 L Transposase
EDIJJJKJ_00856 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EDIJJJKJ_00857 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EDIJJJKJ_00858 2e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EDIJJJKJ_00859 5.2e-62 cysE 2.3.1.30 E serine acetyltransferase
EDIJJJKJ_00860 3.9e-223 L Transposase
EDIJJJKJ_00861 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
EDIJJJKJ_00862 1.1e-115 hsdM 2.1.1.72 V type I restriction-modification system
EDIJJJKJ_00863 7.4e-158 glcU U Glucose uptake
EDIJJJKJ_00864 2e-07 mycA 4.2.1.53 S Myosin-crossreactive antigen
EDIJJJKJ_00865 1.6e-57 V type I restriction-modification system
EDIJJJKJ_00866 1.8e-90 XK27_10720 D peptidase activity
EDIJJJKJ_00867 2.3e-295 adcA P Belongs to the bacterial solute-binding protein 9 family
EDIJJJKJ_00868 1.7e-08
EDIJJJKJ_00870 1.4e-109 L Transposase
EDIJJJKJ_00871 2.5e-46
EDIJJJKJ_00872 7.1e-17
EDIJJJKJ_00873 3.9e-171 yeiH S Membrane
EDIJJJKJ_00874 7.1e-114 mur1 NU muramidase
EDIJJJKJ_00875 1.3e-97 L transposition
EDIJJJKJ_00876 2.6e-166 cpsY K Transcriptional regulator
EDIJJJKJ_00877 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EDIJJJKJ_00878 5.6e-58 phnA P Alkylphosphonate utilization operon protein PhnA
EDIJJJKJ_00879 2.4e-105 artQ P ABC transporter (Permease
EDIJJJKJ_00880 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_00881 8.4e-159 aatB ET ABC transporter substrate-binding protein
EDIJJJKJ_00882 5.8e-149 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDIJJJKJ_00883 2.1e-07
EDIJJJKJ_00884 7.8e-25
EDIJJJKJ_00885 7e-37 adhP 1.1.1.1 C alcohol dehydrogenase
EDIJJJKJ_00886 1.8e-15 adhP 1.1.1.1 P alcohol dehydrogenase
EDIJJJKJ_00887 2.4e-81 adhP 1.1.1.1 C alcohol dehydrogenase
EDIJJJKJ_00888 2.7e-22
EDIJJJKJ_00889 0.0 res_1 3.1.21.5 S Type III restriction
EDIJJJKJ_00890 1.2e-263 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EDIJJJKJ_00891 8.8e-93 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EDIJJJKJ_00892 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EDIJJJKJ_00893 1.6e-126 gntR1 K transcriptional
EDIJJJKJ_00894 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EDIJJJKJ_00895 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EDIJJJKJ_00896 3.1e-87 niaX
EDIJJJKJ_00897 2.3e-90 niaR S small molecule binding protein (contains 3H domain)
EDIJJJKJ_00898 5.6e-129 K DNA-binding helix-turn-helix protein
EDIJJJKJ_00899 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EDIJJJKJ_00900 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDIJJJKJ_00901 3.7e-168 GK ROK family
EDIJJJKJ_00902 8.3e-159 dprA LU DNA protecting protein DprA
EDIJJJKJ_00903 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EDIJJJKJ_00904 1.5e-152 S TraX protein
EDIJJJKJ_00905 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDIJJJKJ_00906 2.8e-252 T PhoQ Sensor
EDIJJJKJ_00907 2.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EDIJJJKJ_00908 2e-154 XK27_05470 E Methionine synthase
EDIJJJKJ_00909 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EDIJJJKJ_00910 7.3e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDIJJJKJ_00911 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
EDIJJJKJ_00912 6.6e-54 IQ Acetoin reductase
EDIJJJKJ_00913 3.9e-19 IQ Acetoin reductase
EDIJJJKJ_00914 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EDIJJJKJ_00918 1.1e-53 K peptidyl-tyrosine sulfation
EDIJJJKJ_00919 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDIJJJKJ_00922 1.1e-212 pqqE C radical SAM domain protein
EDIJJJKJ_00923 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
EDIJJJKJ_00924 6.6e-61 EGP Major facilitator Superfamily
EDIJJJKJ_00925 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EDIJJJKJ_00926 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EDIJJJKJ_00927 1.9e-13
EDIJJJKJ_00928 2e-132 L Transposase
EDIJJJKJ_00929 4.6e-13 L Transposase
EDIJJJKJ_00930 2.2e-115 V ABC transporter (Permease
EDIJJJKJ_00931 3.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EDIJJJKJ_00932 1.6e-10
EDIJJJKJ_00933 6.9e-98 K Transcriptional regulator, TetR family
EDIJJJKJ_00934 2.3e-159 czcD P cation diffusion facilitator family transporter
EDIJJJKJ_00935 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EDIJJJKJ_00936 7.5e-135 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EDIJJJKJ_00937 8.1e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EDIJJJKJ_00938 6e-08 S Hydrolases of the alpha beta superfamily
EDIJJJKJ_00939 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
EDIJJJKJ_00940 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
EDIJJJKJ_00943 6.9e-144 2.4.2.3 F Phosphorylase superfamily
EDIJJJKJ_00944 9.8e-120 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EDIJJJKJ_00945 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
EDIJJJKJ_00946 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
EDIJJJKJ_00947 5.3e-93 dinF V Mate efflux family protein
EDIJJJKJ_00948 4.5e-36 dinF V drug transmembrane transporter activity
EDIJJJKJ_00950 6e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EDIJJJKJ_00952 9.7e-89 S TraX protein
EDIJJJKJ_00953 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EDIJJJKJ_00954 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EDIJJJKJ_00955 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EDIJJJKJ_00956 2.8e-111 cas1 L maintenance of DNA repeat elements
EDIJJJKJ_00957 2.2e-69 cas1 L maintenance of DNA repeat elements
EDIJJJKJ_00958 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDIJJJKJ_00959 6.8e-133 cas6 S Pfam:DUF2276
EDIJJJKJ_00960 0.0 csm1 S CRISPR-associated protein Csm1 family
EDIJJJKJ_00961 5.6e-62 csm2 L Pfam:DUF310
EDIJJJKJ_00962 8.1e-117 csm3 L RAMP superfamily
EDIJJJKJ_00963 4e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
EDIJJJKJ_00964 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
EDIJJJKJ_00965 3e-25 csm6 S Psort location Cytoplasmic, score
EDIJJJKJ_00966 2.5e-64 csm6 S Psort location Cytoplasmic, score
EDIJJJKJ_00967 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EDIJJJKJ_00968 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EDIJJJKJ_00970 9.3e-55 nylA 3.5.1.4 J Belongs to the amidase family
EDIJJJKJ_00971 6.5e-268 dtpT E transporter
EDIJJJKJ_00972 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_00973 2.2e-106 nylA 3.5.1.4 J Belongs to the amidase family
EDIJJJKJ_00974 4.6e-73 yckB ET Belongs to the bacterial solute-binding protein 3 family
EDIJJJKJ_00975 3.2e-59 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
EDIJJJKJ_00976 3.3e-68 yecS P ABC transporter (Permease
EDIJJJKJ_00977 9.2e-22 yecS P amino acid transport
EDIJJJKJ_00979 3e-281 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EDIJJJKJ_00980 1.9e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
EDIJJJKJ_00981 1.2e-106 yfiF3 K sequence-specific DNA binding
EDIJJJKJ_00982 2e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EDIJJJKJ_00983 6.9e-240 agcS E (Alanine) symporter
EDIJJJKJ_00984 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EDIJJJKJ_00985 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
EDIJJJKJ_00986 1.8e-59 Q phosphatase activity
EDIJJJKJ_00987 9.3e-62 S haloacid dehalogenase-like hydrolase
EDIJJJKJ_00988 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EDIJJJKJ_00989 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EDIJJJKJ_00990 5.1e-139 XK27_04775 S hemerythrin HHE cation binding domain
EDIJJJKJ_00991 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
EDIJJJKJ_00992 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EDIJJJKJ_00993 1.7e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EDIJJJKJ_00994 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EDIJJJKJ_00995 2.3e-44 yktA S Belongs to the UPF0223 family
EDIJJJKJ_00996 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EDIJJJKJ_00997 5.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EDIJJJKJ_00998 5.6e-158 pstS P phosphate
EDIJJJKJ_00999 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
EDIJJJKJ_01000 1.2e-155 pstA P phosphate transport system permease
EDIJJJKJ_01001 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDIJJJKJ_01002 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDIJJJKJ_01003 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
EDIJJJKJ_01004 0.0 pepN 3.4.11.2 E aminopeptidase
EDIJJJKJ_01005 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EDIJJJKJ_01007 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
EDIJJJKJ_01008 8.9e-08
EDIJJJKJ_01009 3.2e-08
EDIJJJKJ_01010 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EDIJJJKJ_01011 4.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EDIJJJKJ_01012 3.7e-182 malR K Transcriptional regulator
EDIJJJKJ_01013 2e-19 malX G ABC transporter
EDIJJJKJ_01014 4.5e-17 malX G maltose binding
EDIJJJKJ_01015 1.8e-68 malX G maltose binding
EDIJJJKJ_01016 1.3e-125 malF P ABC transporter (Permease
EDIJJJKJ_01017 1.9e-13
EDIJJJKJ_01018 4.6e-25 tatA U protein secretion
EDIJJJKJ_01019 6.9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EDIJJJKJ_01020 3.1e-306 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EDIJJJKJ_01021 1.5e-233 ycdB P peroxidase
EDIJJJKJ_01022 2.3e-151 ycdO P periplasmic lipoprotein involved in iron transport
EDIJJJKJ_01023 2.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
EDIJJJKJ_01024 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
EDIJJJKJ_01025 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDIJJJKJ_01026 1.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDIJJJKJ_01027 1.8e-30 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDIJJJKJ_01028 3.9e-113 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDIJJJKJ_01029 1.6e-210 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDIJJJKJ_01030 2.1e-207 L Transposase
EDIJJJKJ_01031 1.7e-07 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
EDIJJJKJ_01032 2e-103 L nUDIX hydrolase
EDIJJJKJ_01033 3.2e-172 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EDIJJJKJ_01034 6.7e-156 K Transcriptional activator, Rgg GadR MutR family
EDIJJJKJ_01035 1.8e-234 L Transposase
EDIJJJKJ_01036 6.4e-69 3.2.1.17 M lysozyme activity
EDIJJJKJ_01037 0.0 lpdA 1.8.1.4 C Dehydrogenase
EDIJJJKJ_01038 4.2e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EDIJJJKJ_01039 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EDIJJJKJ_01040 4.6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EDIJJJKJ_01041 4.6e-38 P membrane protein (DUF2207)
EDIJJJKJ_01042 9.7e-65 S the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01043 2.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EDIJJJKJ_01044 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EDIJJJKJ_01045 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EDIJJJKJ_01046 2.4e-23 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EDIJJJKJ_01047 5.3e-178 3.4.16.4 M Belongs to the peptidase S11 family
EDIJJJKJ_01048 1.3e-159 rssA S Phospholipase, patatin family
EDIJJJKJ_01049 4.6e-85 estA E GDSL-like protein
EDIJJJKJ_01050 2.2e-293 S unusual protein kinase
EDIJJJKJ_01051 1.3e-39 S granule-associated protein
EDIJJJKJ_01052 1.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDIJJJKJ_01053 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
EDIJJJKJ_01054 9.5e-100 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDIJJJKJ_01055 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
EDIJJJKJ_01056 8.5e-199 S hmm pf01594
EDIJJJKJ_01057 6.2e-44 G alpha-ribazole phosphatase activity
EDIJJJKJ_01058 1.2e-33 G Belongs to the phosphoglycerate mutase family
EDIJJJKJ_01059 1.1e-93 V VanZ like family
EDIJJJKJ_01060 5.6e-144 L Transposase
EDIJJJKJ_01061 3.2e-192 wbbI M transferase activity, transferring glycosyl groups
EDIJJJKJ_01062 2.3e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
EDIJJJKJ_01063 1.8e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
EDIJJJKJ_01064 3.1e-152 S Acyltransferase family
EDIJJJKJ_01065 7e-251 epsU S Polysaccharide biosynthesis protein
EDIJJJKJ_01066 1.5e-83 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EDIJJJKJ_01067 1.4e-246 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EDIJJJKJ_01068 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EDIJJJKJ_01069 3.1e-93 yfeJ 6.3.5.2 F glutamine amidotransferase
EDIJJJKJ_01070 6.8e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EDIJJJKJ_01071 2.9e-88 S Protein of unknown function (DUF1697)
EDIJJJKJ_01072 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EDIJJJKJ_01073 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EDIJJJKJ_01074 5.7e-08 V Glucan-binding protein C
EDIJJJKJ_01075 2.1e-22 V Glucan-binding protein C
EDIJJJKJ_01076 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
EDIJJJKJ_01077 1.6e-276 pepV 3.5.1.18 E Dipeptidase
EDIJJJKJ_01078 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EDIJJJKJ_01079 1.4e-86 XK27_03610 K Gnat family
EDIJJJKJ_01080 1.6e-24 L Transposase
EDIJJJKJ_01081 6.2e-25 L Transposase
EDIJJJKJ_01082 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EDIJJJKJ_01083 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EDIJJJKJ_01084 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EDIJJJKJ_01085 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EDIJJJKJ_01086 5e-23 M LysM domain
EDIJJJKJ_01087 2.9e-90 ebsA S Family of unknown function (DUF5322)
EDIJJJKJ_01088 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EDIJJJKJ_01089 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDIJJJKJ_01090 3.7e-224 G COG0457 FOG TPR repeat
EDIJJJKJ_01091 2.7e-179 yubA S permease
EDIJJJKJ_01092 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EDIJJJKJ_01093 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EDIJJJKJ_01094 3.2e-124 ftsE D cell division ATP-binding protein FtsE
EDIJJJKJ_01095 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EDIJJJKJ_01096 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EDIJJJKJ_01097 1.3e-181 yjjH S Calcineurin-like phosphoesterase
EDIJJJKJ_01098 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EDIJJJKJ_01099 0.0 pacL 3.6.3.8 P cation transport ATPase
EDIJJJKJ_01100 2.6e-67 ywiB S Domain of unknown function (DUF1934)
EDIJJJKJ_01101 1.7e-51 XK27_00115 2.3.1.128 K acetyltransferase
EDIJJJKJ_01102 9.2e-147 yidA S hydrolases of the HAD superfamily
EDIJJJKJ_01103 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EDIJJJKJ_01104 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EDIJJJKJ_01105 1.3e-235 vicK 2.7.13.3 T Histidine kinase
EDIJJJKJ_01106 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDIJJJKJ_01107 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_01108 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDIJJJKJ_01109 2.7e-118 gltJ P ABC transporter (Permease
EDIJJJKJ_01110 1.7e-111 tcyB_2 P ABC transporter (permease)
EDIJJJKJ_01111 2e-142 endA F DNA RNA non-specific endonuclease
EDIJJJKJ_01112 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
EDIJJJKJ_01113 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDIJJJKJ_01114 1e-08 S Protein of unknown function (DUF1146)
EDIJJJKJ_01115 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDIJJJKJ_01116 7e-27 G Domain of unknown function (DUF4832)
EDIJJJKJ_01117 2.7e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EDIJJJKJ_01118 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EDIJJJKJ_01120 1.4e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDIJJJKJ_01121 9.4e-89 ytsP 1.8.4.14 T GAF domain-containing protein
EDIJJJKJ_01122 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EDIJJJKJ_01123 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
EDIJJJKJ_01126 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EDIJJJKJ_01127 5.5e-220 XK27_05110 P chloride
EDIJJJKJ_01128 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EDIJJJKJ_01129 2e-283 clcA P Chloride transporter, ClC family
EDIJJJKJ_01130 5.1e-75 fld C Flavodoxin
EDIJJJKJ_01131 2.6e-08 XK27_08880
EDIJJJKJ_01132 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
EDIJJJKJ_01133 1.6e-151 estA CE1 S Putative esterase
EDIJJJKJ_01134 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDIJJJKJ_01135 1.2e-135 XK27_08845 S abc transporter atp-binding protein
EDIJJJKJ_01136 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EDIJJJKJ_01137 2.5e-178 XK27_08835 S ABC transporter substrate binding protein
EDIJJJKJ_01138 3.2e-17 S Domain of unknown function (DUF4649)
EDIJJJKJ_01140 2.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01141 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01143 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01145 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EDIJJJKJ_01146 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EDIJJJKJ_01147 0.0 dnaE 2.7.7.7 L DNA polymerase
EDIJJJKJ_01148 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
EDIJJJKJ_01149 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDIJJJKJ_01150 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDIJJJKJ_01151 1.3e-42 ysdA L Membrane
EDIJJJKJ_01152 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EDIJJJKJ_01153 2e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EDIJJJKJ_01154 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EDIJJJKJ_01155 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EDIJJJKJ_01157 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EDIJJJKJ_01158 6.8e-96 ypmS S Protein conserved in bacteria
EDIJJJKJ_01159 9e-148 ypmR E lipolytic protein G-D-S-L family
EDIJJJKJ_01160 1.7e-148 DegV S DegV family
EDIJJJKJ_01161 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
EDIJJJKJ_01162 7.5e-74 argR K arginine binding
EDIJJJKJ_01163 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EDIJJJKJ_01164 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EDIJJJKJ_01165 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
EDIJJJKJ_01166 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDIJJJKJ_01169 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EDIJJJKJ_01170 2.9e-125 dnaD
EDIJJJKJ_01171 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EDIJJJKJ_01172 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EDIJJJKJ_01173 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EDIJJJKJ_01174 2.3e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDIJJJKJ_01175 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EDIJJJKJ_01176 7.9e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDIJJJKJ_01177 1.9e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EDIJJJKJ_01178 3e-241 rodA D Belongs to the SEDS family
EDIJJJKJ_01179 2.1e-91 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EDIJJJKJ_01180 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EDIJJJKJ_01181 2.6e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EDIJJJKJ_01182 1.8e-121 ylfI S tigr01906
EDIJJJKJ_01183 1.7e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EDIJJJKJ_01184 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
EDIJJJKJ_01185 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
EDIJJJKJ_01189 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EDIJJJKJ_01190 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EDIJJJKJ_01191 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EDIJJJKJ_01192 1.3e-207 yurR 1.4.5.1 E oxidoreductase
EDIJJJKJ_01193 1.1e-24 zupT P transporter
EDIJJJKJ_01194 2.4e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
EDIJJJKJ_01195 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EDIJJJKJ_01196 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
EDIJJJKJ_01197 1.3e-70 gtrA S GtrA-like protein
EDIJJJKJ_01198 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EDIJJJKJ_01199 6e-169 ybbR S Protein conserved in bacteria
EDIJJJKJ_01200 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EDIJJJKJ_01201 8.3e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EDIJJJKJ_01202 8.7e-150 cobQ S glutamine amidotransferase
EDIJJJKJ_01203 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EDIJJJKJ_01204 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
EDIJJJKJ_01205 0.0 uup S abc transporter atp-binding protein
EDIJJJKJ_01206 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EDIJJJKJ_01207 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
EDIJJJKJ_01208 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EDIJJJKJ_01209 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EDIJJJKJ_01210 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EDIJJJKJ_01211 7.9e-39 ptsH G phosphocarrier protein Hpr
EDIJJJKJ_01212 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
EDIJJJKJ_01213 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
EDIJJJKJ_01214 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EDIJJJKJ_01215 2.2e-34 nrdH O Glutaredoxin
EDIJJJKJ_01216 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDIJJJKJ_01217 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDIJJJKJ_01219 1.1e-74 L Transposase (IS116 IS110 IS902 family)
EDIJJJKJ_01220 2.1e-64 L Transposase (IS116 IS110 IS902 family)
EDIJJJKJ_01221 1.8e-165 ypuA S secreted protein
EDIJJJKJ_01222 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
EDIJJJKJ_01223 9.3e-59 srtA 3.4.22.70 M Sortase family
EDIJJJKJ_01224 1.1e-59 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EDIJJJKJ_01225 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDIJJJKJ_01226 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EDIJJJKJ_01227 2.6e-258 noxE P NADH oxidase
EDIJJJKJ_01228 2.5e-294 yfmM S abc transporter atp-binding protein
EDIJJJKJ_01229 5.4e-46 XK27_01265 S ECF-type riboflavin transporter, S component
EDIJJJKJ_01230 5.4e-09 XK27_01265 S ECF-type riboflavin transporter, S component
EDIJJJKJ_01231 5.5e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EDIJJJKJ_01232 2e-86 S ECF-type riboflavin transporter, S component
EDIJJJKJ_01234 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EDIJJJKJ_01235 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EDIJJJKJ_01238 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDIJJJKJ_01239 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDIJJJKJ_01240 3.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EDIJJJKJ_01241 0.0 smc D Required for chromosome condensation and partitioning
EDIJJJKJ_01242 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EDIJJJKJ_01243 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EDIJJJKJ_01244 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EDIJJJKJ_01245 7.2e-91 alkD L Dna alkylation repair
EDIJJJKJ_01246 2.8e-93 pat 2.3.1.183 M acetyltransferase
EDIJJJKJ_01247 3.3e-12
EDIJJJKJ_01248 6.6e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EDIJJJKJ_01249 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EDIJJJKJ_01250 7.9e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EDIJJJKJ_01251 3.3e-66 bioY S biotin transmembrane transporter activity
EDIJJJKJ_01252 3.6e-90 proW P Binding-protein-dependent transport system inner membrane component
EDIJJJKJ_01253 1.5e-138 proV E abc transporter atp-binding protein
EDIJJJKJ_01254 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
EDIJJJKJ_01255 3e-111 proWZ P ABC transporter (Permease
EDIJJJKJ_01256 8.1e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
EDIJJJKJ_01257 5.4e-206 S Protein of unknown function (DUF917)
EDIJJJKJ_01258 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EDIJJJKJ_01259 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
EDIJJJKJ_01260 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase
EDIJJJKJ_01261 3.3e-26
EDIJJJKJ_01262 2.9e-145 S ABC-2 family transporter protein
EDIJJJKJ_01263 6.6e-99 S transport system, permease component
EDIJJJKJ_01264 6.1e-103 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDIJJJKJ_01265 2.5e-187 desK 2.7.13.3 T Histidine kinase
EDIJJJKJ_01266 4.8e-134 yvfS V ABC-2 type transporter
EDIJJJKJ_01267 2.3e-159 XK27_09825 V abc transporter atp-binding protein
EDIJJJKJ_01270 4.6e-166 yocS S Transporter
EDIJJJKJ_01271 1.2e-84 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
EDIJJJKJ_01272 2.6e-35 XK27_05000 S metal cluster binding
EDIJJJKJ_01273 0.0 V ABC transporter (permease)
EDIJJJKJ_01274 2.2e-134 macB2 V ABC transporter, ATP-binding protein
EDIJJJKJ_01275 7.4e-167 T Histidine kinase
EDIJJJKJ_01276 2.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDIJJJKJ_01277 3.4e-17 xpt 2.4.2.22, 2.4.2.7 F purine ribonucleoside salvage
EDIJJJKJ_01278 1.4e-50 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EDIJJJKJ_01280 2.6e-136 pbuX F xanthine permease
EDIJJJKJ_01281 5.9e-247 norM V Multidrug efflux pump
EDIJJJKJ_01282 2.5e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDIJJJKJ_01283 1.2e-165 L integrase core domain
EDIJJJKJ_01284 1.5e-121 L Transposase
EDIJJJKJ_01285 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
EDIJJJKJ_01286 1e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDIJJJKJ_01287 7e-50 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDIJJJKJ_01288 9.6e-26 csbD K CsbD-like
EDIJJJKJ_01289 6.2e-228 yfnA E amino acid
EDIJJJKJ_01290 2.5e-109 XK27_02070 S nitroreductase
EDIJJJKJ_01291 2.2e-90 1.13.11.2 S glyoxalase
EDIJJJKJ_01292 5.6e-77 ywnA K Transcriptional regulator
EDIJJJKJ_01293 1.9e-158 E Alpha/beta hydrolase of unknown function (DUF915)
EDIJJJKJ_01294 2.3e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDIJJJKJ_01295 2.9e-111 drgA C Nitroreductase
EDIJJJKJ_01296 3.5e-87 yoaK S Protein of unknown function (DUF1275)
EDIJJJKJ_01298 1.2e-160 yvgN C reductase
EDIJJJKJ_01299 1.1e-55 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDIJJJKJ_01300 2.4e-09
EDIJJJKJ_01301 3.1e-115 S Abortive infection C-terminus
EDIJJJKJ_01302 0.0 L DEAD-like helicases superfamily
EDIJJJKJ_01303 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EDIJJJKJ_01304 7.8e-285 XK27_07020 S Belongs to the UPF0371 family
EDIJJJKJ_01306 6.7e-38 BP1961 P nitric oxide dioxygenase activity
EDIJJJKJ_01307 4.4e-36 K the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01308 2.4e-54 K response regulator
EDIJJJKJ_01309 1.3e-68 S Signal peptide protein, YSIRK family
EDIJJJKJ_01311 7.6e-61
EDIJJJKJ_01312 1.2e-271 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDIJJJKJ_01313 4.1e-139
EDIJJJKJ_01314 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
EDIJJJKJ_01315 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
EDIJJJKJ_01316 5.8e-109 MA20_06410 E LysE type translocator
EDIJJJKJ_01317 2.7e-09
EDIJJJKJ_01318 0.0 M family 8
EDIJJJKJ_01319 0.0 sbcC L ATPase involved in DNA repair
EDIJJJKJ_01320 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EDIJJJKJ_01321 0.0 lacL 3.2.1.23 G -beta-galactosidase
EDIJJJKJ_01322 0.0 lacS G transporter
EDIJJJKJ_01323 3.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EDIJJJKJ_01324 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDIJJJKJ_01325 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDIJJJKJ_01326 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EDIJJJKJ_01327 2.3e-184 galR K Transcriptional regulator
EDIJJJKJ_01328 7.1e-09 L Integrase core domain protein
EDIJJJKJ_01329 1.2e-25 L transposition
EDIJJJKJ_01330 3e-198 M translation initiation factor activity
EDIJJJKJ_01331 4.6e-68 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EDIJJJKJ_01332 1.3e-76 V abc transporter atp-binding protein
EDIJJJKJ_01333 1e-41 V (ABC) transporter
EDIJJJKJ_01334 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EDIJJJKJ_01335 2.3e-87 L Transposase
EDIJJJKJ_01336 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EDIJJJKJ_01337 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EDIJJJKJ_01338 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EDIJJJKJ_01339 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EDIJJJKJ_01342 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDIJJJKJ_01343 1.7e-174 vraS 2.7.13.3 T Histidine kinase
EDIJJJKJ_01344 3.7e-120 yvqF KT membrane
EDIJJJKJ_01345 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EDIJJJKJ_01346 2e-132 stp 3.1.3.16 T phosphatase
EDIJJJKJ_01347 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EDIJJJKJ_01348 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EDIJJJKJ_01349 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EDIJJJKJ_01350 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EDIJJJKJ_01351 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EDIJJJKJ_01352 1.8e-219 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EDIJJJKJ_01353 3.8e-148 XK27_02985 S overlaps another CDS with the same product name
EDIJJJKJ_01354 3.1e-147 supH S overlaps another CDS with the same product name
EDIJJJKJ_01355 8.6e-63 yvoA_1 K Transcriptional
EDIJJJKJ_01356 9.8e-121 skfE V abc transporter atp-binding protein
EDIJJJKJ_01357 3.3e-133 V ATPase activity
EDIJJJKJ_01358 4.3e-172 oppF P Belongs to the ABC transporter superfamily
EDIJJJKJ_01359 2.2e-204 oppD P Belongs to the ABC transporter superfamily
EDIJJJKJ_01360 4.9e-168 amiD P ABC transporter (Permease
EDIJJJKJ_01361 2.1e-277 amiC P ABC transporter (Permease
EDIJJJKJ_01362 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EDIJJJKJ_01363 3.9e-237 L Transposase
EDIJJJKJ_01364 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EDIJJJKJ_01365 1.1e-83 oppF P Belongs to the ABC transporter superfamily
EDIJJJKJ_01366 6.9e-22 tatD L hydrolase, TatD family'
EDIJJJKJ_01367 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
EDIJJJKJ_01368 1e-110 L PFAM Integrase catalytic region
EDIJJJKJ_01369 9.3e-29 L transposition
EDIJJJKJ_01370 4.3e-23 L transposase activity
EDIJJJKJ_01371 3.3e-39 L transposase activity
EDIJJJKJ_01372 1.7e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EDIJJJKJ_01373 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EDIJJJKJ_01374 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EDIJJJKJ_01375 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EDIJJJKJ_01376 1.5e-103 yjbK S Adenylate cyclase
EDIJJJKJ_01377 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDIJJJKJ_01378 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
EDIJJJKJ_01379 9e-59 XK27_04120 S Putative amino acid metabolism
EDIJJJKJ_01380 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EDIJJJKJ_01381 7.2e-132 puuD T peptidase C26
EDIJJJKJ_01382 6.2e-120 radC E Belongs to the UPF0758 family
EDIJJJKJ_01383 0.0 rgpF M Rhamnan synthesis protein F
EDIJJJKJ_01384 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EDIJJJKJ_01385 3e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EDIJJJKJ_01386 2.8e-143 rgpC GM Transport permease protein
EDIJJJKJ_01387 7.5e-180 rgpB GT2 M Glycosyltransferase, group 2 family protein
EDIJJJKJ_01388 4.4e-227 rgpA GT4 M Domain of unknown function (DUF1972)
EDIJJJKJ_01389 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
EDIJJJKJ_01390 2.3e-224 amrA S polysaccharide biosynthetic process
EDIJJJKJ_01391 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
EDIJJJKJ_01392 3.4e-126 ycbB S Glycosyl transferase family 2
EDIJJJKJ_01393 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EDIJJJKJ_01394 9.9e-247
EDIJJJKJ_01395 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EDIJJJKJ_01396 6.3e-252 M Psort location CytoplasmicMembrane, score
EDIJJJKJ_01397 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EDIJJJKJ_01398 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EDIJJJKJ_01399 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EDIJJJKJ_01400 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EDIJJJKJ_01401 2.9e-137 gltS ET Belongs to the bacterial solute-binding protein 3 family
EDIJJJKJ_01402 2.8e-202 arcT 2.6.1.1 E Aminotransferase
EDIJJJKJ_01403 6.5e-137 ET Belongs to the bacterial solute-binding protein 3 family
EDIJJJKJ_01404 1.3e-143 ET Belongs to the bacterial solute-binding protein 3 family
EDIJJJKJ_01405 2.2e-84 mutT 3.6.1.55 F Nudix family
EDIJJJKJ_01406 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EDIJJJKJ_01407 6.5e-57 V CAAX protease self-immunity
EDIJJJKJ_01408 7.6e-32 S CAAX amino terminal protease family protein
EDIJJJKJ_01409 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EDIJJJKJ_01410 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_01411 1.1e-16 XK27_00735
EDIJJJKJ_01412 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EDIJJJKJ_01414 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDIJJJKJ_01417 2.3e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
EDIJJJKJ_01418 7.7e-52 V Psort location Cytoplasmic, score
EDIJJJKJ_01419 2.3e-156 K sequence-specific DNA binding
EDIJJJKJ_01420 8.9e-253 C Arylsulfatase regulator (Fe-S oxidoreductase)
EDIJJJKJ_01421 2.1e-288 V (ABC) transporter
EDIJJJKJ_01422 9.6e-10
EDIJJJKJ_01423 1.9e-43 S Domain of unknown function (DUF4299)
EDIJJJKJ_01424 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
EDIJJJKJ_01425 5.9e-155 EG Permeases of the drug metabolite transporter (DMT) superfamily
EDIJJJKJ_01427 3.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
EDIJJJKJ_01428 2.1e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EDIJJJKJ_01429 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDIJJJKJ_01430 2.6e-109 3.1.3.18 S IA, variant 1
EDIJJJKJ_01431 3.2e-116 lrgB M effector of murein hydrolase
EDIJJJKJ_01432 2.2e-58 lrgA S Effector of murein hydrolase LrgA
EDIJJJKJ_01434 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
EDIJJJKJ_01435 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EDIJJJKJ_01436 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDIJJJKJ_01437 1.3e-104 wecD M Acetyltransferase (GNAT) domain
EDIJJJKJ_01438 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EDIJJJKJ_01439 5.4e-116 GK ROK family
EDIJJJKJ_01440 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
EDIJJJKJ_01441 1e-115 XK27_08050 O HflC and HflK could regulate a protease
EDIJJJKJ_01443 2.3e-206 potD P spermidine putrescine ABC transporter
EDIJJJKJ_01444 4.3e-133 potC P ABC-type spermidine putrescine transport system, permease component II
EDIJJJKJ_01445 1.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
EDIJJJKJ_01446 3.6e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EDIJJJKJ_01447 4.6e-171 murB 1.3.1.98 M cell wall formation
EDIJJJKJ_01448 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EDIJJJKJ_01449 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EDIJJJKJ_01450 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EDIJJJKJ_01451 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EDIJJJKJ_01452 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
EDIJJJKJ_01453 0.0 ydaO E amino acid
EDIJJJKJ_01454 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDIJJJKJ_01455 4.1e-37 ylqC L Belongs to the UPF0109 family
EDIJJJKJ_01456 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EDIJJJKJ_01457 6.9e-172 tehB 2.1.1.265 Q Methyltransferase
EDIJJJKJ_01458 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
EDIJJJKJ_01459 2.8e-74 S QueT transporter
EDIJJJKJ_01460 5.2e-121 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
EDIJJJKJ_01461 4.3e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EDIJJJKJ_01462 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EDIJJJKJ_01463 1.3e-85 ccl S cog cog4708
EDIJJJKJ_01464 7.4e-164 rbn E Belongs to the UPF0761 family
EDIJJJKJ_01465 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EDIJJJKJ_01466 1.7e-232 ytoI K transcriptional regulator containing CBS domains
EDIJJJKJ_01467 3.7e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EDIJJJKJ_01468 3.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDIJJJKJ_01469 0.0 comEC S Competence protein ComEC
EDIJJJKJ_01470 4e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EDIJJJKJ_01471 1.3e-142 plsC 2.3.1.51 I Acyltransferase
EDIJJJKJ_01472 1.4e-82 nodB3 G polysaccharide deacetylase
EDIJJJKJ_01473 4.1e-49 nodB3 G polysaccharide deacetylase
EDIJJJKJ_01474 9.3e-141 yabB 2.1.1.223 L Methyltransferase
EDIJJJKJ_01475 1e-41 yazA L endonuclease containing a URI domain
EDIJJJKJ_01476 2.8e-256 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EDIJJJKJ_01477 2.3e-154 corA P CorA-like protein
EDIJJJKJ_01478 2.5e-62 yjqA S Bacterial PH domain
EDIJJJKJ_01479 7.8e-100 thiT S Thiamine transporter
EDIJJJKJ_01480 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDIJJJKJ_01481 3.2e-201 yjbB G Permeases of the major facilitator superfamily
EDIJJJKJ_01482 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EDIJJJKJ_01483 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
EDIJJJKJ_01484 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EDIJJJKJ_01487 8.8e-156 cjaA ET ABC transporter substrate-binding protein
EDIJJJKJ_01488 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_01489 7.8e-107 P ABC transporter (Permease
EDIJJJKJ_01490 6e-115 papP P ABC transporter (Permease
EDIJJJKJ_01491 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EDIJJJKJ_01492 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
EDIJJJKJ_01493 0.0 copA 3.6.3.54 P P-type ATPase
EDIJJJKJ_01494 1.6e-73 copY K negative regulation of transcription, DNA-templated
EDIJJJKJ_01495 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EDIJJJKJ_01496 3.5e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EDIJJJKJ_01497 1.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EDIJJJKJ_01498 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EDIJJJKJ_01499 3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EDIJJJKJ_01500 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EDIJJJKJ_01501 7.4e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EDIJJJKJ_01502 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
EDIJJJKJ_01503 3.2e-56
EDIJJJKJ_01504 0.0 ctpE P E1-E2 ATPase
EDIJJJKJ_01505 2.7e-25
EDIJJJKJ_01506 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EDIJJJKJ_01507 1.9e-46 L transposase activity
EDIJJJKJ_01508 9.9e-115 K transcriptional regulator, MerR family
EDIJJJKJ_01509 3.7e-105 dnaQ 2.7.7.7 L DNA polymerase III
EDIJJJKJ_01510 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
EDIJJJKJ_01511 7.4e-64 XK27_02560 S cog cog2151
EDIJJJKJ_01512 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDIJJJKJ_01513 7.7e-227 ytfP S Flavoprotein
EDIJJJKJ_01515 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EDIJJJKJ_01516 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
EDIJJJKJ_01517 1.2e-183 ecsB U ABC transporter
EDIJJJKJ_01518 2.3e-133 ecsA V abc transporter atp-binding protein
EDIJJJKJ_01519 6e-73 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EDIJJJKJ_01520 2.8e-11
EDIJJJKJ_01521 3.2e-110
EDIJJJKJ_01522 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EDIJJJKJ_01523 2.6e-205 ylbM S Belongs to the UPF0348 family
EDIJJJKJ_01524 7.7e-140 yqeM Q Methyltransferase domain protein
EDIJJJKJ_01525 3.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EDIJJJKJ_01526 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EDIJJJKJ_01527 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EDIJJJKJ_01528 3.5e-49 yhbY J RNA-binding protein
EDIJJJKJ_01529 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EDIJJJKJ_01530 1.8e-98 yqeG S hydrolase of the HAD superfamily
EDIJJJKJ_01531 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EDIJJJKJ_01532 1.4e-65
EDIJJJKJ_01533 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDIJJJKJ_01534 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EDIJJJKJ_01535 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDIJJJKJ_01536 4.4e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
EDIJJJKJ_01537 7.4e-32 M lipopolysaccharide 3-alpha-galactosyltransferase activity
EDIJJJKJ_01538 1.6e-57 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDIJJJKJ_01539 6.5e-181 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDIJJJKJ_01540 1.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDIJJJKJ_01541 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
EDIJJJKJ_01542 3e-101 pncA Q isochorismatase
EDIJJJKJ_01543 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EDIJJJKJ_01544 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EDIJJJKJ_01545 2.4e-75 XK27_03180 T universal stress protein
EDIJJJKJ_01548 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDIJJJKJ_01549 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EDIJJJKJ_01550 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EDIJJJKJ_01551 0.0 yjcE P NhaP-type Na H and K H antiporters
EDIJJJKJ_01553 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
EDIJJJKJ_01554 1.3e-184 yhcC S radical SAM protein
EDIJJJKJ_01555 4.9e-196 ylbL T Belongs to the peptidase S16 family
EDIJJJKJ_01556 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EDIJJJKJ_01557 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
EDIJJJKJ_01558 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EDIJJJKJ_01559 2.8e-08 S Protein of unknown function (DUF4059)
EDIJJJKJ_01560 3.4e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
EDIJJJKJ_01561 1.1e-173 yxeN P ABC transporter (Permease
EDIJJJKJ_01562 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDIJJJKJ_01564 1.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDIJJJKJ_01565 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EDIJJJKJ_01566 1.2e-148 cah 4.2.1.1 P carbonic anhydrase
EDIJJJKJ_01567 2.7e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDIJJJKJ_01568 5e-47 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
EDIJJJKJ_01569 1.3e-47 D nuclear chromosome segregation
EDIJJJKJ_01570 1.9e-35 D nuclear chromosome segregation
EDIJJJKJ_01571 3.4e-82 L DNA integration
EDIJJJKJ_01572 1.3e-125 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
EDIJJJKJ_01573 1.5e-127 ybbM S transport system, permease component
EDIJJJKJ_01574 9.4e-118 ybbL S abc transporter atp-binding protein
EDIJJJKJ_01575 2.9e-29
EDIJJJKJ_01576 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EDIJJJKJ_01577 4.6e-140 cppA E CppA N-terminal
EDIJJJKJ_01578 2.7e-29 V CAAX protease self-immunity
EDIJJJKJ_01579 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EDIJJJKJ_01580 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EDIJJJKJ_01583 2e-46 spiA K sequence-specific DNA binding
EDIJJJKJ_01584 1.2e-137 blpT
EDIJJJKJ_01585 3.9e-122 L Transposase
EDIJJJKJ_01586 1.2e-165 L integrase core domain
EDIJJJKJ_01591 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
EDIJJJKJ_01592 6.8e-133 agrA KT phosphorelay signal transduction system
EDIJJJKJ_01593 3.8e-238 blpH 2.7.13.3 T protein histidine kinase activity
EDIJJJKJ_01595 4.5e-158 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDIJJJKJ_01596 2.7e-44 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDIJJJKJ_01597 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDIJJJKJ_01598 0.0 mdlB V abc transporter atp-binding protein
EDIJJJKJ_01599 0.0 mdlA V abc transporter atp-binding protein
EDIJJJKJ_01601 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
EDIJJJKJ_01602 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EDIJJJKJ_01603 2.3e-72 yutD J protein conserved in bacteria
EDIJJJKJ_01604 1.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EDIJJJKJ_01606 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EDIJJJKJ_01607 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EDIJJJKJ_01608 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EDIJJJKJ_01609 5.6e-47 ftsL D cell division protein FtsL
EDIJJJKJ_01610 3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EDIJJJKJ_01611 3.3e-162
EDIJJJKJ_01612 6.3e-31 yhaI J Protein of unknown function (DUF805)
EDIJJJKJ_01613 3.5e-10 D nuclear chromosome segregation
EDIJJJKJ_01614 6.9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EDIJJJKJ_01615 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EDIJJJKJ_01616 1.4e-287 XK27_00765
EDIJJJKJ_01617 1.1e-89 ecsA_2 V abc transporter atp-binding protein
EDIJJJKJ_01618 2e-45 ecsA_2 V ATPase activity
EDIJJJKJ_01619 1.5e-104 S Protein of unknown function (DUF554)
EDIJJJKJ_01620 1.6e-11 S Protein of unknown function (DUF554)
EDIJJJKJ_01621 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EDIJJJKJ_01622 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EDIJJJKJ_01623 2.6e-66 liaI S membrane
EDIJJJKJ_01624 7.7e-09 XK27_02470 K LytTr DNA-binding domain protein
EDIJJJKJ_01625 3.6e-66 KT response to antibiotic
EDIJJJKJ_01626 9.1e-18 KT response to antibiotic
EDIJJJKJ_01627 9.1e-91 yebC M Membrane
EDIJJJKJ_01628 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
EDIJJJKJ_01629 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EDIJJJKJ_01630 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EDIJJJKJ_01631 6.2e-186 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EDIJJJKJ_01632 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EDIJJJKJ_01633 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDIJJJKJ_01634 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDIJJJKJ_01635 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EDIJJJKJ_01637 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDIJJJKJ_01638 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EDIJJJKJ_01639 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
EDIJJJKJ_01640 4.1e-291 scrB 3.2.1.26 GH32 G invertase
EDIJJJKJ_01641 2.9e-179 scrR K Transcriptional
EDIJJJKJ_01642 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EDIJJJKJ_01643 3.4e-62 yqhY S protein conserved in bacteria
EDIJJJKJ_01644 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EDIJJJKJ_01645 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
EDIJJJKJ_01646 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EDIJJJKJ_01648 1e-09 V 'abc transporter, ATP-binding protein
EDIJJJKJ_01649 3.2e-20 V 'abc transporter, ATP-binding protein
EDIJJJKJ_01650 2.5e-36 V ATPase activity
EDIJJJKJ_01653 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EDIJJJKJ_01654 2e-169 corA P COG0598 Mg2 and Co2 transporters
EDIJJJKJ_01655 4.1e-124 XK27_01040 S Pfam PF06570
EDIJJJKJ_01657 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EDIJJJKJ_01658 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDIJJJKJ_01659 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EDIJJJKJ_01661 2.8e-28 XK27_05745
EDIJJJKJ_01662 4.2e-230 mutY L A G-specific adenine glycosylase
EDIJJJKJ_01666 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EDIJJJKJ_01667 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EDIJJJKJ_01668 1.3e-93 cvpA S toxin biosynthetic process
EDIJJJKJ_01669 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EDIJJJKJ_01670 3.6e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDIJJJKJ_01671 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDIJJJKJ_01672 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EDIJJJKJ_01673 8.8e-48 azlD E branched-chain amino acid
EDIJJJKJ_01674 3.8e-117 azlC E AzlC protein
EDIJJJKJ_01675 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EDIJJJKJ_01676 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EDIJJJKJ_01677 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EDIJJJKJ_01678 2.5e-33 ykzG S Belongs to the UPF0356 family
EDIJJJKJ_01679 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDIJJJKJ_01680 7.6e-263 glnA 6.3.1.2 E glutamine synthetase
EDIJJJKJ_01681 8.5e-63 glnR K Transcriptional regulator
EDIJJJKJ_01682 1.3e-87 S Fusaric acid resistance protein-like
EDIJJJKJ_01683 3e-13
EDIJJJKJ_01684 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EDIJJJKJ_01685 5.5e-42 L Transposase
EDIJJJKJ_01686 9.4e-46 L transposase activity
EDIJJJKJ_01687 5.7e-23 L Transposase
EDIJJJKJ_01688 3.5e-55 L transposition
EDIJJJKJ_01689 4.5e-88 L Integrase core domain protein
EDIJJJKJ_01690 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EDIJJJKJ_01691 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EDIJJJKJ_01692 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EDIJJJKJ_01693 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EDIJJJKJ_01694 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_01695 8.2e-143 purR 2.4.2.22, 2.4.2.7 F operon repressor
EDIJJJKJ_01696 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
EDIJJJKJ_01697 6.9e-173 rmuC S RmuC domain protein
EDIJJJKJ_01698 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
EDIJJJKJ_01699 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EDIJJJKJ_01700 1.2e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EDIJJJKJ_01702 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EDIJJJKJ_01703 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EDIJJJKJ_01704 1.4e-144 tatD L Hydrolase, tatd
EDIJJJKJ_01705 1.5e-74 yccU S CoA-binding protein
EDIJJJKJ_01706 4.8e-51 trxA O Belongs to the thioredoxin family
EDIJJJKJ_01707 7.8e-143 S Macro domain protein
EDIJJJKJ_01708 2.7e-09 L thioesterase
EDIJJJKJ_01709 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
EDIJJJKJ_01712 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EDIJJJKJ_01713 1.6e-87 L Transposase
EDIJJJKJ_01714 1e-13 rpmH J Ribosomal protein L34
EDIJJJKJ_01715 6.9e-187 jag S RNA-binding protein
EDIJJJKJ_01716 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDIJJJKJ_01717 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EDIJJJKJ_01718 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
EDIJJJKJ_01719 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EDIJJJKJ_01720 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EDIJJJKJ_01721 1.4e-81 amiA E transmembrane transport
EDIJJJKJ_01722 4.9e-75 amiA E transmembrane transport
EDIJJJKJ_01723 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EDIJJJKJ_01724 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EDIJJJKJ_01725 9.2e-51 S Protein of unknown function (DUF3397)
EDIJJJKJ_01726 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EDIJJJKJ_01727 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
EDIJJJKJ_01728 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
EDIJJJKJ_01729 4.8e-227 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EDIJJJKJ_01730 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EDIJJJKJ_01731 4.1e-65 XK27_09620 S FMN reductase (NADPH) activity
EDIJJJKJ_01732 8.3e-34 XK27_09620 S FMN reductase (NADPH) activity
EDIJJJKJ_01733 6.6e-34 XK27_09615 S FMN reductase (NADPH) activity
EDIJJJKJ_01734 1.9e-132 XK27_09615 S PAS domain
EDIJJJKJ_01735 6.5e-75 fnt P Formate nitrite transporter
EDIJJJKJ_01736 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
EDIJJJKJ_01737 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EDIJJJKJ_01738 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EDIJJJKJ_01739 1.2e-165 L integrase core domain
EDIJJJKJ_01740 1.5e-121 L Transposase
EDIJJJKJ_01741 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EDIJJJKJ_01742 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EDIJJJKJ_01743 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EDIJJJKJ_01744 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EDIJJJKJ_01745 2.7e-48 S glycolate biosynthetic process
EDIJJJKJ_01746 4e-65 S phosphatase activity
EDIJJJKJ_01747 5.7e-160 rrmA 2.1.1.187 Q methyltransferase
EDIJJJKJ_01750 9.2e-92 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EDIJJJKJ_01751 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDIJJJKJ_01752 6.4e-37 yeeD O sulfur carrier activity
EDIJJJKJ_01753 1.6e-191 yeeE S Sulphur transport
EDIJJJKJ_01754 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDIJJJKJ_01755 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EDIJJJKJ_01756 1.8e-09 S Domain of unknown function (DUF4651)
EDIJJJKJ_01757 2.6e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EDIJJJKJ_01758 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EDIJJJKJ_01759 1.8e-111 S CAAX amino terminal protease family protein
EDIJJJKJ_01761 7.6e-68 V CAAX protease self-immunity
EDIJJJKJ_01762 8.8e-27 lanR K sequence-specific DNA binding
EDIJJJKJ_01763 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDIJJJKJ_01764 1.3e-176 ytxK 2.1.1.72 L DNA methylase
EDIJJJKJ_01765 8.9e-13 comGF U Putative Competence protein ComGF
EDIJJJKJ_01766 4e-72 comGF U Competence protein ComGF
EDIJJJKJ_01767 1.4e-15 NU Type II secretory pathway pseudopilin
EDIJJJKJ_01768 1.8e-57 cglD NU Competence protein
EDIJJJKJ_01769 8.5e-43 comGC U Required for transformation and DNA binding
EDIJJJKJ_01770 9.2e-153 cglB NU type II secretion system
EDIJJJKJ_01771 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EDIJJJKJ_01772 1e-68 S cog cog4699
EDIJJJKJ_01773 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDIJJJKJ_01774 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDIJJJKJ_01775 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDIJJJKJ_01776 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EDIJJJKJ_01777 1.2e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EDIJJJKJ_01778 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
EDIJJJKJ_01779 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EDIJJJKJ_01780 6.1e-282 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDIJJJKJ_01781 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDIJJJKJ_01782 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
EDIJJJKJ_01783 1.4e-57 asp S cog cog1302
EDIJJJKJ_01784 8.4e-227 norM V Mate efflux family protein
EDIJJJKJ_01785 1.9e-278 thrC 4.2.3.1 E Threonine synthase
EDIJJJKJ_01786 8.3e-63 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDIJJJKJ_01787 7.2e-36 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
EDIJJJKJ_01788 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDIJJJKJ_01789 1.1e-103 1.1.1.1, 1.1.99.1, 1.2.1.10, 1.2.1.18, 1.2.1.27, 1.2.1.3 C Dehydrogenase
EDIJJJKJ_01790 3.2e-31 C belongs to the aldehyde dehydrogenase family
EDIJJJKJ_01791 5.1e-66 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
EDIJJJKJ_01792 0.0 pepO 3.4.24.71 O Peptidase family M13
EDIJJJKJ_01793 2.3e-120 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDIJJJKJ_01794 7e-67 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDIJJJKJ_01795 2e-56 treB 2.7.1.201 G PTS System
EDIJJJKJ_01796 5.8e-21 treR K DNA-binding transcription factor activity
EDIJJJKJ_01797 7.8e-88 treR K trehalose operon
EDIJJJKJ_01798 3.3e-95 ywlG S Belongs to the UPF0340 family
EDIJJJKJ_01801 2.7e-13 L PFAM Integrase, catalytic core
EDIJJJKJ_01802 5.1e-78 L PFAM Integrase, catalytic core
EDIJJJKJ_01803 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EDIJJJKJ_01805 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_01806 2.1e-111 6.3.2.2 H ergothioneine biosynthetic process
EDIJJJKJ_01807 1.1e-16 6.3.2.2 H gamma-glutamylcysteine synthetase
EDIJJJKJ_01808 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
EDIJJJKJ_01809 2.7e-13 L PFAM Integrase, catalytic core
EDIJJJKJ_01810 4e-75 L PFAM Integrase, catalytic core
EDIJJJKJ_01811 3.3e-62 rplQ J ribosomal protein l17
EDIJJJKJ_01812 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDIJJJKJ_01813 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EDIJJJKJ_01814 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EDIJJJKJ_01815 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EDIJJJKJ_01816 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EDIJJJKJ_01817 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EDIJJJKJ_01818 2.5e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EDIJJJKJ_01819 7.4e-58 rplO J binds to the 23S rRNA
EDIJJJKJ_01820 2.5e-23 rpmD J ribosomal protein l30
EDIJJJKJ_01821 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EDIJJJKJ_01822 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EDIJJJKJ_01823 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EDIJJJKJ_01824 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EDIJJJKJ_01825 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EDIJJJKJ_01826 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EDIJJJKJ_01827 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EDIJJJKJ_01828 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EDIJJJKJ_01829 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EDIJJJKJ_01830 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EDIJJJKJ_01831 3.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EDIJJJKJ_01832 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EDIJJJKJ_01833 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EDIJJJKJ_01834 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EDIJJJKJ_01835 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EDIJJJKJ_01836 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EDIJJJKJ_01837 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
EDIJJJKJ_01838 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EDIJJJKJ_01839 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EDIJJJKJ_01840 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EDIJJJKJ_01841 0.0 XK27_09800 I Acyltransferase
EDIJJJKJ_01842 1.7e-35 XK27_09805 S MORN repeat protein
EDIJJJKJ_01843 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EDIJJJKJ_01844 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EDIJJJKJ_01845 8.9e-95 adk 2.7.4.3 F topology modulation protein
EDIJJJKJ_01847 1.4e-223 L Transposase
EDIJJJKJ_01849 3.4e-155 Z012_04635 K sequence-specific DNA binding
EDIJJJKJ_01850 0.0 KLT serine threonine protein kinase
EDIJJJKJ_01851 2.1e-280 V ABC transporter
EDIJJJKJ_01852 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDIJJJKJ_01853 1.3e-128 Z012_04635 K sequence-specific DNA binding
EDIJJJKJ_01855 3.6e-232 C Radical SAM
EDIJJJKJ_01856 3.9e-287 V ABC transporter transmembrane region
EDIJJJKJ_01857 5.9e-156 L Replication initiation factor
EDIJJJKJ_01858 1.9e-18 S Domain of unknown function (DUF3173)
EDIJJJKJ_01859 3.5e-216 int L Belongs to the 'phage' integrase family
EDIJJJKJ_01861 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EDIJJJKJ_01862 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EDIJJJKJ_01863 2.2e-44 yrzL S Belongs to the UPF0297 family
EDIJJJKJ_01864 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EDIJJJKJ_01865 4.2e-44 yrzB S Belongs to the UPF0473 family
EDIJJJKJ_01866 3.5e-302 ccs S the current gene model (or a revised gene model) may contain a frame shift
EDIJJJKJ_01867 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EDIJJJKJ_01868 7.5e-14
EDIJJJKJ_01869 3.4e-91 XK27_10930 K acetyltransferase
EDIJJJKJ_01870 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDIJJJKJ_01871 2.2e-145 yaaA S Belongs to the UPF0246 family
EDIJJJKJ_01872 3.4e-169 XK27_01785 S cog cog1284
EDIJJJKJ_01873 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EDIJJJKJ_01875 1.2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
EDIJJJKJ_01876 1.6e-129 metE 2.1.1.14 E Methionine synthase
EDIJJJKJ_01877 1.4e-36 metE 2.1.1.14 E Methionine synthase
EDIJJJKJ_01878 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EDIJJJKJ_01879 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EDIJJJKJ_01882 4.8e-51 yegS 2.7.1.107 I lipid kinase activity
EDIJJJKJ_01883 8.5e-97 S Hydrophobic domain protein
EDIJJJKJ_01885 7.4e-28 S Membrane
EDIJJJKJ_01886 1.4e-101
EDIJJJKJ_01887 1.8e-23 S Small integral membrane protein
EDIJJJKJ_01888 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_01889 6.6e-86 M Protein conserved in bacteria
EDIJJJKJ_01890 2.8e-12 K CsbD-like
EDIJJJKJ_01891 2.8e-102 nudL L hydrolase
EDIJJJKJ_01892 3.4e-13 nudL L hydrolase
EDIJJJKJ_01893 4e-19 K negative regulation of transcription, DNA-templated
EDIJJJKJ_01894 4.4e-24 K negative regulation of transcription, DNA-templated
EDIJJJKJ_01896 2.3e-108 S Putative adhesin
EDIJJJKJ_01897 5.6e-160 XK27_06930 V domain protein
EDIJJJKJ_01898 6.4e-96 XK27_06935 K transcriptional regulator
EDIJJJKJ_01899 4.8e-55 ypaA S membrane
EDIJJJKJ_01900 2.7e-08
EDIJJJKJ_01901 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EDIJJJKJ_01902 8.2e-48 veg S Biofilm formation stimulator VEG
EDIJJJKJ_01903 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EDIJJJKJ_01904 6.7e-70 rplI J binds to the 23S rRNA
EDIJJJKJ_01905 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EDIJJJKJ_01906 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EDIJJJKJ_01907 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EDIJJJKJ_01908 0.0 S Bacterial membrane protein, YfhO
EDIJJJKJ_01909 2e-93 isaA GH23 M Immunodominant staphylococcal antigen A
EDIJJJKJ_01910 3.1e-93 lytE M LysM domain protein
EDIJJJKJ_01911 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDIJJJKJ_01912 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDIJJJKJ_01913 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDIJJJKJ_01914 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EDIJJJKJ_01915 1.7e-138 ymfM S sequence-specific DNA binding
EDIJJJKJ_01916 3.1e-242 ymfH S Peptidase M16
EDIJJJKJ_01917 4.8e-235 ymfF S Peptidase M16
EDIJJJKJ_01918 1.6e-45 yaaA S S4 domain protein YaaA
EDIJJJKJ_01919 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EDIJJJKJ_01920 2.8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EDIJJJKJ_01921 9.4e-183 L Transposase and inactivated derivatives IS30 family
EDIJJJKJ_01922 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EDIJJJKJ_01923 5.4e-153 yvjA S membrane
EDIJJJKJ_01924 6.7e-306 ybiT S abc transporter atp-binding protein
EDIJJJKJ_01925 0.0 XK27_10405 S Bacterial membrane protein YfhO
EDIJJJKJ_01929 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
EDIJJJKJ_01930 8.6e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EDIJJJKJ_01931 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EDIJJJKJ_01932 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)