ORF_ID e_value Gene_name EC_number CAZy COGs Description
DOFFCFEK_00001 1.3e-91 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DOFFCFEK_00002 1.4e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOFFCFEK_00003 1.1e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOFFCFEK_00004 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOFFCFEK_00005 3.5e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DOFFCFEK_00007 3.1e-111 K response regulator
DOFFCFEK_00008 1e-167 arlS 2.7.13.3 T Histidine kinase
DOFFCFEK_00009 2.9e-120 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFFCFEK_00010 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DOFFCFEK_00011 1.8e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DOFFCFEK_00012 7.3e-105
DOFFCFEK_00013 5.5e-117
DOFFCFEK_00014 1.3e-41 dut S dUTPase
DOFFCFEK_00015 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOFFCFEK_00016 3.7e-46 yqhY S Asp23 family, cell envelope-related function
DOFFCFEK_00017 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOFFCFEK_00018 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOFFCFEK_00019 4.4e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFFCFEK_00020 9.6e-17 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFFCFEK_00021 1.6e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFFCFEK_00022 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DOFFCFEK_00023 6.6e-49 argR K Regulates arginine biosynthesis genes
DOFFCFEK_00024 1.9e-178 recN L May be involved in recombinational repair of damaged DNA
DOFFCFEK_00025 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOFFCFEK_00026 2.2e-30 ynzC S UPF0291 protein
DOFFCFEK_00027 2.9e-26 yneF S UPF0154 protein
DOFFCFEK_00028 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
DOFFCFEK_00029 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
DOFFCFEK_00030 7.2e-75 yciQ P membrane protein (DUF2207)
DOFFCFEK_00031 1.3e-19 D nuclear chromosome segregation
DOFFCFEK_00032 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOFFCFEK_00033 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOFFCFEK_00034 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
DOFFCFEK_00035 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
DOFFCFEK_00036 1.5e-156 glk 2.7.1.2 G Glucokinase
DOFFCFEK_00037 8e-46 yqhL P Rhodanese-like protein
DOFFCFEK_00038 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
DOFFCFEK_00039 4.2e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOFFCFEK_00040 6.1e-206 ynbB 4.4.1.1 P aluminum resistance
DOFFCFEK_00041 1.7e-45 glnR K Transcriptional regulator
DOFFCFEK_00042 2e-247 glnA 6.3.1.2 E glutamine synthetase
DOFFCFEK_00044 1.8e-10 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DOFFCFEK_00045 2.7e-48 S Domain of unknown function (DUF956)
DOFFCFEK_00046 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DOFFCFEK_00047 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOFFCFEK_00048 4.9e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOFFCFEK_00049 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
DOFFCFEK_00050 6.9e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DOFFCFEK_00051 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOFFCFEK_00052 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFFCFEK_00053 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
DOFFCFEK_00054 3.7e-170 nusA K Participates in both transcription termination and antitermination
DOFFCFEK_00055 1.4e-39 ylxR K Protein of unknown function (DUF448)
DOFFCFEK_00056 3.4e-25 ylxQ J ribosomal protein
DOFFCFEK_00057 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOFFCFEK_00058 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOFFCFEK_00059 9.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOFFCFEK_00060 1.1e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DOFFCFEK_00061 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOFFCFEK_00062 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOFFCFEK_00063 1.5e-274 dnaK O Heat shock 70 kDa protein
DOFFCFEK_00064 7e-161 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOFFCFEK_00065 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOFFCFEK_00067 1.3e-204 glnP P ABC transporter
DOFFCFEK_00068 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFFCFEK_00069 1.5e-31
DOFFCFEK_00070 7.7e-111 ampC V Beta-lactamase
DOFFCFEK_00071 3.5e-110 cobQ S glutamine amidotransferase
DOFFCFEK_00072 1.8e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
DOFFCFEK_00073 6.8e-86 tdk 2.7.1.21 F thymidine kinase
DOFFCFEK_00074 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOFFCFEK_00075 1.2e-88 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOFFCFEK_00076 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOFFCFEK_00077 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOFFCFEK_00078 2.9e-96 atpB C it plays a direct role in the translocation of protons across the membrane
DOFFCFEK_00079 1.3e-18 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFFCFEK_00080 9.9e-41 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOFFCFEK_00081 5.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFFCFEK_00082 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOFFCFEK_00083 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOFFCFEK_00084 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOFFCFEK_00085 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DOFFCFEK_00086 4.1e-15 ywzB S Protein of unknown function (DUF1146)
DOFFCFEK_00087 2.1e-196 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOFFCFEK_00088 3.4e-167 mbl D Cell shape determining protein MreB Mrl
DOFFCFEK_00089 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DOFFCFEK_00090 1.3e-13 S Protein of unknown function (DUF2969)
DOFFCFEK_00091 6.1e-187 rodA D Belongs to the SEDS family
DOFFCFEK_00092 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
DOFFCFEK_00093 4.3e-94 2.7.1.89 M Phosphotransferase enzyme family
DOFFCFEK_00094 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DOFFCFEK_00095 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DOFFCFEK_00096 1.5e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOFFCFEK_00097 9.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOFFCFEK_00098 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOFFCFEK_00099 1.5e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOFFCFEK_00100 1.1e-90 stp 3.1.3.16 T phosphatase
DOFFCFEK_00101 1.8e-192 KLT serine threonine protein kinase
DOFFCFEK_00102 4.9e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOFFCFEK_00103 4.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
DOFFCFEK_00104 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DOFFCFEK_00105 4.5e-53 asp S Asp23 family, cell envelope-related function
DOFFCFEK_00106 1.5e-239 yloV S DAK2 domain fusion protein YloV
DOFFCFEK_00107 4.4e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOFFCFEK_00108 1e-139 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOFFCFEK_00109 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOFFCFEK_00110 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOFFCFEK_00111 8.5e-213 smc D Required for chromosome condensation and partitioning
DOFFCFEK_00112 1.2e-148 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOFFCFEK_00113 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOFFCFEK_00114 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOFFCFEK_00115 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DOFFCFEK_00116 1.1e-26 ylqC S Belongs to the UPF0109 family
DOFFCFEK_00117 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOFFCFEK_00118 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DOFFCFEK_00119 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
DOFFCFEK_00120 1.8e-198 yfnA E amino acid
DOFFCFEK_00121 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOFFCFEK_00122 8.1e-202 L Belongs to the 'phage' integrase family
DOFFCFEK_00125 1.3e-88 S AAA domain
DOFFCFEK_00126 1.1e-15 S Pfam:DUF955
DOFFCFEK_00127 3.8e-20 xre K Helix-turn-helix domain
DOFFCFEK_00131 2.6e-08 K Helix-turn-helix XRE-family like proteins
DOFFCFEK_00132 2.4e-120 K Phage regulatory protein
DOFFCFEK_00136 6.1e-19
DOFFCFEK_00137 1.4e-14 K Cro/C1-type HTH DNA-binding domain
DOFFCFEK_00141 8.6e-76 S Siphovirus Gp157
DOFFCFEK_00142 1.3e-241 res L Helicase C-terminal domain protein
DOFFCFEK_00143 5.6e-117 L AAA domain
DOFFCFEK_00144 1.3e-85
DOFFCFEK_00145 2.8e-140 S Bifunctional DNA primase/polymerase, N-terminal
DOFFCFEK_00146 1e-232 S Virulence-associated protein E
DOFFCFEK_00147 3.1e-50 S VRR_NUC
DOFFCFEK_00152 4.4e-34 arpU S Phage transcriptional regulator, ArpU family
DOFFCFEK_00153 1.4e-32
DOFFCFEK_00156 1.2e-83 L HNH nucleases
DOFFCFEK_00157 4.3e-83 L Phage terminase, small subunit
DOFFCFEK_00158 0.0 S Phage Terminase
DOFFCFEK_00160 2.8e-213 S Phage portal protein
DOFFCFEK_00161 7.2e-119 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
DOFFCFEK_00162 7.6e-222 S Phage capsid family
DOFFCFEK_00163 1.8e-21 S Phage gp6-like head-tail connector protein
DOFFCFEK_00164 3.5e-58 S Phage head-tail joining protein
DOFFCFEK_00165 5.6e-65 S Bacteriophage HK97-gp10, putative tail-component
DOFFCFEK_00166 2e-64 S Protein of unknown function (DUF806)
DOFFCFEK_00167 2.9e-125 S Phage tail tube protein
DOFFCFEK_00168 8.2e-54 S Phage tail assembly chaperone proteins, TAC
DOFFCFEK_00170 3.2e-115 M by MetaGeneAnnotator
DOFFCFEK_00172 2.3e-280 M Phage tail tape measure protein TP901
DOFFCFEK_00173 9.2e-126 S Phage tail protein
DOFFCFEK_00174 2.6e-277 rny D peptidase
DOFFCFEK_00178 1.6e-15 G cellulose 1,4-beta-cellobiosidase activity
DOFFCFEK_00179 1.2e-14 S Bacteriophage holin family
DOFFCFEK_00180 4.8e-115 S N-acetylmuramoyl-L-alanine amidase activity
DOFFCFEK_00181 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
DOFFCFEK_00182 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOFFCFEK_00183 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOFFCFEK_00184 4.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFFCFEK_00185 1.2e-17 S Tetratricopeptide repeat
DOFFCFEK_00186 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOFFCFEK_00187 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOFFCFEK_00188 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOFFCFEK_00189 7.3e-248 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOFFCFEK_00190 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFFCFEK_00191 5e-23 ykzG S Belongs to the UPF0356 family
DOFFCFEK_00192 2.1e-24
DOFFCFEK_00193 2.4e-85 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOFFCFEK_00194 4.5e-30 1.1.1.27 C L-malate dehydrogenase activity
DOFFCFEK_00195 1.5e-24 yktA S Belongs to the UPF0223 family
DOFFCFEK_00196 2.8e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DOFFCFEK_00197 0.0 typA T GTP-binding protein TypA
DOFFCFEK_00198 4.6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
DOFFCFEK_00199 1.6e-114 manY G PTS system
DOFFCFEK_00200 3.3e-148 manN G system, mannose fructose sorbose family IID component
DOFFCFEK_00201 5.1e-101 ftsW D Belongs to the SEDS family
DOFFCFEK_00202 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DOFFCFEK_00203 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DOFFCFEK_00204 1.6e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DOFFCFEK_00205 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOFFCFEK_00206 4.1e-131 ylbL T Belongs to the peptidase S16 family
DOFFCFEK_00207 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DOFFCFEK_00208 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFCFEK_00209 8.9e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFCFEK_00210 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFFCFEK_00211 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOFFCFEK_00212 5.3e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DOFFCFEK_00213 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOFFCFEK_00214 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DOFFCFEK_00215 1.9e-162 purD 6.3.4.13 F Belongs to the GARS family
DOFFCFEK_00216 3e-70 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DOFFCFEK_00217 9.3e-130 S Dynamin family
DOFFCFEK_00218 5.5e-24 S Dynamin family
DOFFCFEK_00219 5.9e-09
DOFFCFEK_00220 2.2e-21
DOFFCFEK_00221 0.0 S Domain of unknown function DUF87
DOFFCFEK_00222 1.1e-45 S nuclease activity
DOFFCFEK_00223 5.9e-109 S Acyltransferase family
DOFFCFEK_00224 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOFFCFEK_00225 6.6e-122 K LysR substrate binding domain
DOFFCFEK_00227 2.2e-20
DOFFCFEK_00228 2.3e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DOFFCFEK_00229 4.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
DOFFCFEK_00230 5.2e-50 comEA L Competence protein ComEA
DOFFCFEK_00231 2e-69 comEB 3.5.4.12 F ComE operon protein 2
DOFFCFEK_00232 3.6e-156 comEC S Competence protein ComEC
DOFFCFEK_00233 2.7e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
DOFFCFEK_00234 1.5e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOFFCFEK_00235 1.3e-135 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DOFFCFEK_00236 2.2e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DOFFCFEK_00237 6.2e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DOFFCFEK_00238 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DOFFCFEK_00239 1.8e-36 ypmB S Protein conserved in bacteria
DOFFCFEK_00240 9e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DOFFCFEK_00241 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DOFFCFEK_00242 1.7e-56 dnaD L DnaD domain protein
DOFFCFEK_00243 1.1e-81 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOFFCFEK_00244 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOFFCFEK_00245 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFFCFEK_00246 9.5e-93 M transferase activity, transferring glycosyl groups
DOFFCFEK_00247 2.8e-84 M Glycosyltransferase sugar-binding region containing DXD motif
DOFFCFEK_00248 4.4e-100 epsJ1 M Glycosyltransferase like family 2
DOFFCFEK_00251 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DOFFCFEK_00252 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DOFFCFEK_00253 1.8e-56 yqeY S YqeY-like protein
DOFFCFEK_00255 5.1e-68 xerD L Phage integrase, N-terminal SAM-like domain
DOFFCFEK_00256 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFFCFEK_00257 8.2e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOFFCFEK_00258 2.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOFFCFEK_00259 2.5e-275 yfmR S ABC transporter, ATP-binding protein
DOFFCFEK_00260 1.5e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOFFCFEK_00261 2.1e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOFFCFEK_00263 1.1e-79 ypmR E GDSL-like Lipase/Acylhydrolase
DOFFCFEK_00264 4.4e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
DOFFCFEK_00265 1.1e-23 yozE S Belongs to the UPF0346 family
DOFFCFEK_00266 8e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOFFCFEK_00267 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFFCFEK_00268 6.2e-85 dprA LU DNA protecting protein DprA
DOFFCFEK_00269 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOFFCFEK_00270 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DOFFCFEK_00271 2.9e-204 G PTS system Galactitol-specific IIC component
DOFFCFEK_00272 2.3e-152 M Exporter of polyketide antibiotics
DOFFCFEK_00273 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DOFFCFEK_00274 7.9e-35 S Repeat protein
DOFFCFEK_00275 2.4e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOFFCFEK_00277 1.7e-15
DOFFCFEK_00280 1.3e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFFCFEK_00281 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFFCFEK_00282 9.1e-43 yodB K Transcriptional regulator, HxlR family
DOFFCFEK_00283 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOFFCFEK_00284 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFFCFEK_00285 1.2e-128 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DOFFCFEK_00286 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
DOFFCFEK_00287 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOFFCFEK_00288 8e-203 hsdM 2.1.1.72 V type I restriction-modification system
DOFFCFEK_00289 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DOFFCFEK_00291 1.8e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
DOFFCFEK_00292 5.7e-57 3.6.1.27 I Acid phosphatase homologues
DOFFCFEK_00293 8.7e-68 maa 2.3.1.79 S Maltose acetyltransferase
DOFFCFEK_00294 1.4e-75 2.3.1.178 M GNAT acetyltransferase
DOFFCFEK_00296 1.1e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
DOFFCFEK_00297 7.8e-65 ypsA S Belongs to the UPF0398 family
DOFFCFEK_00298 3.7e-188 nhaC C Na H antiporter NhaC
DOFFCFEK_00299 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOFFCFEK_00300 2.4e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DOFFCFEK_00301 5.5e-113 xerD D recombinase XerD
DOFFCFEK_00302 1.3e-125 cvfB S S1 domain
DOFFCFEK_00303 4.1e-51 yeaL S Protein of unknown function (DUF441)
DOFFCFEK_00304 2e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOFFCFEK_00305 4.5e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFFCFEK_00306 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOFFCFEK_00307 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOFFCFEK_00308 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFFCFEK_00309 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DOFFCFEK_00310 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DOFFCFEK_00311 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DOFFCFEK_00312 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DOFFCFEK_00313 3.1e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DOFFCFEK_00314 2.1e-15
DOFFCFEK_00315 2.6e-42
DOFFCFEK_00318 1.6e-12
DOFFCFEK_00319 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DOFFCFEK_00320 1e-27 ysxB J Cysteine protease Prp
DOFFCFEK_00321 1.1e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DOFFCFEK_00324 2.2e-08 S Protein of unknown function (DUF2922)
DOFFCFEK_00326 3.7e-16 K DNA-templated transcription, initiation
DOFFCFEK_00328 8.6e-67 H Methyltransferase domain
DOFFCFEK_00329 3.7e-41 cps2D 5.1.3.2 M RmlD substrate binding domain
DOFFCFEK_00330 1.4e-20 cps2D 5.1.3.2 M RmlD substrate binding domain
DOFFCFEK_00331 1.3e-40 wecD M Acetyltransferase (GNAT) family
DOFFCFEK_00333 7.3e-27 ybl78 L Conserved phage C-terminus (Phg_2220_C)
DOFFCFEK_00335 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
DOFFCFEK_00336 3.7e-85 L Restriction endonuclease
DOFFCFEK_00337 3.1e-83 1.1.1.1 C Zinc-binding dehydrogenase
DOFFCFEK_00338 4.1e-31 S CHY zinc finger
DOFFCFEK_00339 3.3e-40 K Transcriptional regulator
DOFFCFEK_00340 7.5e-83 qorB 1.6.5.2 GM NmrA-like family
DOFFCFEK_00341 1.4e-08
DOFFCFEK_00342 7.9e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
DOFFCFEK_00343 5.9e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DOFFCFEK_00344 4.8e-81
DOFFCFEK_00345 4e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
DOFFCFEK_00346 1.8e-113 yitU 3.1.3.104 S hydrolase
DOFFCFEK_00347 1.9e-60 speG J Acetyltransferase (GNAT) domain
DOFFCFEK_00348 1.7e-190 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOFFCFEK_00349 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DOFFCFEK_00350 4.5e-205 pipD E Dipeptidase
DOFFCFEK_00351 1.3e-45
DOFFCFEK_00352 7.7e-64 K helix_turn_helix, arabinose operon control protein
DOFFCFEK_00353 1.1e-51 S Membrane
DOFFCFEK_00354 0.0 rafA 3.2.1.22 G alpha-galactosidase
DOFFCFEK_00355 9.2e-78 L Helicase C-terminal domain protein
DOFFCFEK_00356 3e-147 pbuO_1 S Permease family
DOFFCFEK_00357 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
DOFFCFEK_00358 1.2e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
DOFFCFEK_00359 6.2e-97 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFFCFEK_00360 1.8e-219 cydD CO ABC transporter transmembrane region
DOFFCFEK_00361 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DOFFCFEK_00362 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
DOFFCFEK_00363 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
DOFFCFEK_00364 3.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
DOFFCFEK_00365 8.2e-28 xlyB 3.5.1.28 CBM50 M LysM domain
DOFFCFEK_00366 2.3e-19 glpE P Rhodanese Homology Domain
DOFFCFEK_00367 3.5e-48 lytE M LysM domain protein
DOFFCFEK_00368 4.8e-93 T Calcineurin-like phosphoesterase superfamily domain
DOFFCFEK_00369 1.1e-85 2.7.7.12 C Domain of unknown function (DUF4931)
DOFFCFEK_00371 9.7e-74 draG O ADP-ribosylglycohydrolase
DOFFCFEK_00372 4.2e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFFCFEK_00373 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOFFCFEK_00374 5.1e-62 divIVA D DivIVA domain protein
DOFFCFEK_00375 3.5e-82 ylmH S S4 domain protein
DOFFCFEK_00376 3e-19 yggT S YGGT family
DOFFCFEK_00377 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DOFFCFEK_00378 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOFFCFEK_00379 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOFFCFEK_00380 9.7e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOFFCFEK_00381 4e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOFFCFEK_00382 2e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOFFCFEK_00383 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOFFCFEK_00384 1.7e-280 ftsI 3.4.16.4 M Penicillin-binding Protein
DOFFCFEK_00385 2.5e-11 ftsL D cell division protein FtsL
DOFFCFEK_00386 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOFFCFEK_00387 5.2e-64 mraZ K Belongs to the MraZ family
DOFFCFEK_00388 5.8e-08 S Protein of unknown function (DUF3397)
DOFFCFEK_00389 1.6e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DOFFCFEK_00391 3.7e-99 D Alpha beta
DOFFCFEK_00392 1.8e-108 aatB ET ABC transporter substrate-binding protein
DOFFCFEK_00393 8.2e-90 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFFCFEK_00394 1.9e-94 glnP P ABC transporter permease
DOFFCFEK_00395 6.8e-126 minD D Belongs to the ParA family
DOFFCFEK_00396 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DOFFCFEK_00397 1.2e-54 mreD M rod shape-determining protein MreD
DOFFCFEK_00398 2.1e-88 mreC M Involved in formation and maintenance of cell shape
DOFFCFEK_00399 1.8e-155 mreB D cell shape determining protein MreB
DOFFCFEK_00400 4.5e-21 K Cold shock
DOFFCFEK_00401 6.2e-80 radC L DNA repair protein
DOFFCFEK_00402 8.1e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOFFCFEK_00403 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOFFCFEK_00404 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOFFCFEK_00405 9.9e-163 iscS2 2.8.1.7 E Aminotransferase class V
DOFFCFEK_00406 2.1e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOFFCFEK_00407 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
DOFFCFEK_00408 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOFFCFEK_00409 3.4e-24 yueI S Protein of unknown function (DUF1694)
DOFFCFEK_00410 2e-188 rarA L recombination factor protein RarA
DOFFCFEK_00412 3.2e-73 usp6 T universal stress protein
DOFFCFEK_00413 2.1e-54 tag 3.2.2.20 L glycosylase
DOFFCFEK_00414 6.4e-12
DOFFCFEK_00415 8.7e-144 iunH2 3.2.2.1 F nucleoside hydrolase
DOFFCFEK_00416 3.4e-43 XK27_03960 S Protein of unknown function (DUF3013)
DOFFCFEK_00417 9.9e-118 prmA J Ribosomal protein L11 methyltransferase
DOFFCFEK_00418 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DOFFCFEK_00419 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOFFCFEK_00420 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOFFCFEK_00421 6.7e-57 3.1.3.18 J HAD-hyrolase-like
DOFFCFEK_00422 9.9e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOFFCFEK_00423 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFFCFEK_00424 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOFFCFEK_00425 3.5e-204 pyrP F Permease
DOFFCFEK_00426 3.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFFCFEK_00427 5e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DOFFCFEK_00428 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOFFCFEK_00429 3.3e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOFFCFEK_00430 3.7e-134 K Transcriptional regulator
DOFFCFEK_00431 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
DOFFCFEK_00432 2.5e-114 glcR K DeoR C terminal sensor domain
DOFFCFEK_00433 1.2e-171 patA 2.6.1.1 E Aminotransferase
DOFFCFEK_00434 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOFFCFEK_00436 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOFFCFEK_00437 4.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DOFFCFEK_00438 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
DOFFCFEK_00439 1.5e-22 S Family of unknown function (DUF5322)
DOFFCFEK_00440 2.2e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DOFFCFEK_00441 8e-39
DOFFCFEK_00447 6.7e-150 EGP Sugar (and other) transporter
DOFFCFEK_00448 2.3e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
DOFFCFEK_00449 5.7e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOFFCFEK_00450 2.5e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOFFCFEK_00451 1.4e-67 alkD L DNA alkylation repair enzyme
DOFFCFEK_00452 4.2e-135 EG EamA-like transporter family
DOFFCFEK_00453 8.1e-150 S Tetratricopeptide repeat protein
DOFFCFEK_00454 5.3e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
DOFFCFEK_00455 2.1e-297 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DOFFCFEK_00456 2.7e-126 corA P CorA-like Mg2+ transporter protein
DOFFCFEK_00457 6.5e-161 nhaC C Na H antiporter NhaC
DOFFCFEK_00458 2.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOFFCFEK_00459 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DOFFCFEK_00461 1.2e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOFFCFEK_00462 1.7e-159 iscS 2.8.1.7 E Aminotransferase class V
DOFFCFEK_00463 3.7e-41 XK27_04120 S Putative amino acid metabolism
DOFFCFEK_00464 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOFFCFEK_00465 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DOFFCFEK_00466 7.3e-15 S Protein of unknown function (DUF2929)
DOFFCFEK_00467 0.0 dnaE 2.7.7.7 L DNA polymerase
DOFFCFEK_00468 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DOFFCFEK_00469 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DOFFCFEK_00471 8.7e-23 ypaA S Protein of unknown function (DUF1304)
DOFFCFEK_00472 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOFFCFEK_00473 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFFCFEK_00474 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFFCFEK_00475 1.1e-202 FbpA K Fibronectin-binding protein
DOFFCFEK_00476 3.1e-40 K Transcriptional regulator
DOFFCFEK_00477 1.8e-116 degV S EDD domain protein, DegV family
DOFFCFEK_00478 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
DOFFCFEK_00479 2.4e-40 6.3.3.2 S ASCH
DOFFCFEK_00480 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOFFCFEK_00481 3.5e-80 yjjH S Calcineurin-like phosphoesterase
DOFFCFEK_00482 1.8e-95 EG EamA-like transporter family
DOFFCFEK_00483 1.6e-83 natB CP ABC-type Na efflux pump, permease component
DOFFCFEK_00484 2.4e-111 natA S Domain of unknown function (DUF4162)
DOFFCFEK_00485 3.1e-22 K Acetyltransferase (GNAT) domain
DOFFCFEK_00487 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOFFCFEK_00488 1.3e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DOFFCFEK_00489 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
DOFFCFEK_00490 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
DOFFCFEK_00491 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOFFCFEK_00492 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFCFEK_00493 5.9e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
DOFFCFEK_00494 9e-220 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFFCFEK_00495 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
DOFFCFEK_00496 6.9e-91 recO L Involved in DNA repair and RecF pathway recombination
DOFFCFEK_00497 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOFFCFEK_00498 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DOFFCFEK_00499 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOFFCFEK_00500 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
DOFFCFEK_00501 1.5e-83 lytH 3.5.1.28 M Ami_3
DOFFCFEK_00502 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DOFFCFEK_00503 7.7e-12 M Lysin motif
DOFFCFEK_00504 1.7e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DOFFCFEK_00505 1.7e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
DOFFCFEK_00506 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
DOFFCFEK_00507 1.3e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOFFCFEK_00508 2.9e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOFFCFEK_00509 1.4e-279 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DOFFCFEK_00510 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DOFFCFEK_00511 2.2e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
DOFFCFEK_00512 3.7e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFFCFEK_00513 1.2e-44 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
DOFFCFEK_00514 1.5e-78 3.1.21.3 V Type I restriction modification DNA specificity domain
DOFFCFEK_00515 3.6e-131 L Belongs to the 'phage' integrase family
DOFFCFEK_00516 1.2e-51 3.1.21.3 V PFAM restriction modification system DNA specificity domain
DOFFCFEK_00517 7.1e-21 cutC P Participates in the control of copper homeostasis
DOFFCFEK_00518 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DOFFCFEK_00519 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DOFFCFEK_00520 5.7e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOFFCFEK_00521 5.3e-68 ybbR S YbbR-like protein
DOFFCFEK_00522 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOFFCFEK_00523 2.4e-71 S Protein of unknown function (DUF1361)
DOFFCFEK_00524 1.6e-115 murB 1.3.1.98 M Cell wall formation
DOFFCFEK_00525 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
DOFFCFEK_00526 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DOFFCFEK_00527 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DOFFCFEK_00528 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOFFCFEK_00529 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
DOFFCFEK_00530 3.1e-42 yxjI
DOFFCFEK_00531 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DOFFCFEK_00532 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOFFCFEK_00533 2.8e-19 secG U Preprotein translocase
DOFFCFEK_00534 4.1e-180 clcA P chloride
DOFFCFEK_00535 6e-147 lmrP E Major Facilitator Superfamily
DOFFCFEK_00536 9.2e-169 T PhoQ Sensor
DOFFCFEK_00537 1.9e-103 K response regulator
DOFFCFEK_00538 1.1e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFFCFEK_00539 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOFFCFEK_00540 8.9e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOFFCFEK_00541 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DOFFCFEK_00542 2.9e-174 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOFFCFEK_00543 7.9e-135 cggR K Putative sugar-binding domain
DOFFCFEK_00545 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOFFCFEK_00546 1.8e-149 whiA K May be required for sporulation
DOFFCFEK_00547 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DOFFCFEK_00548 7.5e-126 rapZ S Displays ATPase and GTPase activities
DOFFCFEK_00549 1.3e-79 ylbE GM NAD dependent epimerase dehydratase family protein
DOFFCFEK_00550 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOFFCFEK_00551 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DOFFCFEK_00552 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOFFCFEK_00553 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DOFFCFEK_00554 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOFFCFEK_00555 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOFFCFEK_00556 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DOFFCFEK_00557 3.2e-08 KT PspC domain protein
DOFFCFEK_00558 3.5e-85 phoR 2.7.13.3 T Histidine kinase
DOFFCFEK_00559 3.5e-86 K response regulator
DOFFCFEK_00560 7.7e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
DOFFCFEK_00561 2.1e-162 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOFFCFEK_00562 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOFFCFEK_00563 1.4e-95 yeaN P Major Facilitator Superfamily
DOFFCFEK_00564 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOFFCFEK_00565 4.7e-51 comFC S Competence protein
DOFFCFEK_00566 1.1e-128 comFA L Helicase C-terminal domain protein
DOFFCFEK_00567 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
DOFFCFEK_00568 6.4e-297 ydaO E amino acid
DOFFCFEK_00569 3.4e-252 aha1 P COG COG0474 Cation transport ATPase
DOFFCFEK_00571 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOFFCFEK_00572 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOFFCFEK_00573 1.2e-32 S CAAX protease self-immunity
DOFFCFEK_00574 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOFFCFEK_00575 1e-255 uup S ABC transporter, ATP-binding protein
DOFFCFEK_00576 1.1e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOFFCFEK_00577 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DOFFCFEK_00578 6.3e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DOFFCFEK_00579 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
DOFFCFEK_00580 6.1e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
DOFFCFEK_00581 2.9e-106 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOFFCFEK_00582 1.4e-40 yabA L Involved in initiation control of chromosome replication
DOFFCFEK_00583 2.6e-82 holB 2.7.7.7 L DNA polymerase III
DOFFCFEK_00584 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOFFCFEK_00585 7.1e-29 yaaL S Protein of unknown function (DUF2508)
DOFFCFEK_00586 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOFFCFEK_00587 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOFFCFEK_00588 8.7e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFFCFEK_00589 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOFFCFEK_00590 8.4e-76 rsmC 2.1.1.172 J Methyltransferase
DOFFCFEK_00591 1.2e-27 nrdH O Glutaredoxin
DOFFCFEK_00592 8.2e-45 nrdI F NrdI Flavodoxin like
DOFFCFEK_00593 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFFCFEK_00594 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFFCFEK_00595 9.3e-302 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOFFCFEK_00596 1.8e-54
DOFFCFEK_00597 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOFFCFEK_00598 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOFFCFEK_00599 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOFFCFEK_00600 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOFFCFEK_00601 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
DOFFCFEK_00602 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DOFFCFEK_00603 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOFFCFEK_00604 1.2e-70 yacP S YacP-like NYN domain
DOFFCFEK_00605 3.3e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFFCFEK_00606 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOFFCFEK_00607 3.1e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFFCFEK_00608 3.8e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOFFCFEK_00609 1.4e-153 yacL S domain protein
DOFFCFEK_00610 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOFFCFEK_00611 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DOFFCFEK_00612 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
DOFFCFEK_00613 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
DOFFCFEK_00614 3e-33 S Enterocin A Immunity
DOFFCFEK_00615 2.5e-89 L PFAM Integrase catalytic region
DOFFCFEK_00618 5.2e-35 3.1.21.3 V Type I restriction modification DNA specificity domain
DOFFCFEK_00620 5.2e-18
DOFFCFEK_00621 0.0 mcrB 2.1.1.72 V ATPase family associated with various cellular activities (AAA)
DOFFCFEK_00622 4.8e-164 mcrC V Psort location Cytoplasmic, score
DOFFCFEK_00623 2.4e-101 mod 2.1.1.72, 3.1.21.5 L DNA methylase
DOFFCFEK_00624 9.9e-111 mod 2.1.1.72, 3.1.21.5 L DNA methylase
DOFFCFEK_00625 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
DOFFCFEK_00626 7.2e-186 K DNA binding
DOFFCFEK_00627 0.0 L helicase activity
DOFFCFEK_00628 1.4e-56 S Domain of unknown function (DUF4343)
DOFFCFEK_00629 9.5e-57 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
DOFFCFEK_00630 2.5e-72 S Domain of unknown function (DUF3841)
DOFFCFEK_00631 3e-230 yfjM S Protein of unknown function DUF262
DOFFCFEK_00632 1.2e-174 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
DOFFCFEK_00633 1.8e-156 C Oxidoreductase
DOFFCFEK_00634 1.1e-71 ywlG S Belongs to the UPF0340 family
DOFFCFEK_00635 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DOFFCFEK_00636 3.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOFFCFEK_00637 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOFFCFEK_00638 3.6e-180 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DOFFCFEK_00639 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DOFFCFEK_00640 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOFFCFEK_00641 1.1e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOFFCFEK_00642 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOFFCFEK_00643 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOFFCFEK_00644 2.8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOFFCFEK_00645 1.1e-40 yabR J RNA binding
DOFFCFEK_00646 2.6e-22 divIC D Septum formation initiator
DOFFCFEK_00647 3.6e-31 yabO J S4 domain protein
DOFFCFEK_00648 1.9e-140 yabM S Polysaccharide biosynthesis protein
DOFFCFEK_00649 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOFFCFEK_00650 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOFFCFEK_00651 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOFFCFEK_00652 2.5e-86 S (CBS) domain
DOFFCFEK_00653 4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOFFCFEK_00654 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOFFCFEK_00655 7.2e-53 perR P Belongs to the Fur family
DOFFCFEK_00656 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
DOFFCFEK_00657 2.3e-97 sbcC L Putative exonuclease SbcCD, C subunit
DOFFCFEK_00658 3e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DOFFCFEK_00659 3.2e-48 M LysM domain protein
DOFFCFEK_00660 1.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DOFFCFEK_00661 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DOFFCFEK_00662 3.9e-34 ygfC K Bacterial regulatory proteins, tetR family
DOFFCFEK_00663 8.2e-111 hrtB V ABC transporter permease
DOFFCFEK_00664 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DOFFCFEK_00665 2.7e-42 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOFFCFEK_00666 1.1e-14 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOFFCFEK_00667 0.0 helD 3.6.4.12 L DNA helicase
DOFFCFEK_00668 2e-245 yjbQ P TrkA C-terminal domain protein
DOFFCFEK_00669 1.2e-29
DOFFCFEK_00670 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
DOFFCFEK_00671 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOFFCFEK_00672 9.4e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOFFCFEK_00673 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFCFEK_00674 5.7e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFCFEK_00675 1e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFFCFEK_00676 4.8e-53 rplQ J Ribosomal protein L17
DOFFCFEK_00677 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFCFEK_00678 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOFFCFEK_00679 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOFFCFEK_00680 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DOFFCFEK_00681 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOFFCFEK_00682 4.9e-106 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOFFCFEK_00683 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOFFCFEK_00684 1e-67 rplO J Binds to the 23S rRNA
DOFFCFEK_00685 2.1e-22 rpmD J Ribosomal protein L30
DOFFCFEK_00686 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOFFCFEK_00687 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOFFCFEK_00688 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOFFCFEK_00689 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOFFCFEK_00690 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOFFCFEK_00691 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOFFCFEK_00692 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOFFCFEK_00693 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOFFCFEK_00694 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOFFCFEK_00695 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
DOFFCFEK_00696 8.1e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOFFCFEK_00697 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOFFCFEK_00698 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOFFCFEK_00699 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOFFCFEK_00700 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOFFCFEK_00701 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOFFCFEK_00702 1e-100 rplD J Forms part of the polypeptide exit tunnel
DOFFCFEK_00703 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOFFCFEK_00704 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
DOFFCFEK_00705 6.8e-165 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOFFCFEK_00706 2.2e-79 K rpiR family
DOFFCFEK_00707 1.1e-52 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DOFFCFEK_00708 2.9e-147 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
DOFFCFEK_00709 3.8e-21 K Acetyltransferase (GNAT) domain
DOFFCFEK_00710 1.1e-181 steT E amino acid
DOFFCFEK_00711 9.6e-78 glnP P ABC transporter permease
DOFFCFEK_00712 1.2e-85 gluC P ABC transporter permease
DOFFCFEK_00713 1.1e-99 glnH ET ABC transporter
DOFFCFEK_00714 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFFCFEK_00715 7.6e-09
DOFFCFEK_00716 2.5e-97
DOFFCFEK_00718 3.2e-53 zur P Belongs to the Fur family
DOFFCFEK_00719 1.7e-212 yfnA E Amino Acid
DOFFCFEK_00720 5.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOFFCFEK_00721 0.0 L Helicase C-terminal domain protein
DOFFCFEK_00722 6.5e-81 ptp2 3.1.3.48 T Tyrosine phosphatase family
DOFFCFEK_00723 1.6e-180 yhdP S Transporter associated domain
DOFFCFEK_00724 1.7e-26
DOFFCFEK_00725 2.5e-76 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFFCFEK_00726 1.6e-131 bacI V MacB-like periplasmic core domain
DOFFCFEK_00727 2.5e-97 V ABC transporter
DOFFCFEK_00728 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOFFCFEK_00729 3.1e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
DOFFCFEK_00730 1.6e-140 V MatE
DOFFCFEK_00731 2.4e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFCFEK_00732 3.9e-147 scrR K helix_turn _helix lactose operon repressor
DOFFCFEK_00733 3.1e-217 scrB 3.2.1.26 GH32 G invertase
DOFFCFEK_00734 4e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
DOFFCFEK_00735 9.1e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DOFFCFEK_00736 2.7e-114 ntpJ P Potassium uptake protein
DOFFCFEK_00737 2.8e-58 ktrA P TrkA-N domain
DOFFCFEK_00738 2.1e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DOFFCFEK_00739 6.3e-36 M Glycosyltransferase like family 2
DOFFCFEK_00740 1.4e-19
DOFFCFEK_00741 1.2e-93 S Predicted membrane protein (DUF2207)
DOFFCFEK_00742 1.4e-53 bioY S BioY family
DOFFCFEK_00743 1.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOFFCFEK_00744 7.6e-74 glcR K DeoR C terminal sensor domain
DOFFCFEK_00745 6.5e-60 yceE S haloacid dehalogenase-like hydrolase
DOFFCFEK_00746 5.3e-34 S Domain of unknown function (DUF4811)
DOFFCFEK_00747 1e-196 lmrB EGP Major facilitator Superfamily
DOFFCFEK_00748 1.2e-31 merR K MerR HTH family regulatory protein
DOFFCFEK_00749 7.4e-38 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFCFEK_00750 4e-120 G Bacterial extracellular solute-binding protein
DOFFCFEK_00751 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
DOFFCFEK_00752 3e-99 baeS T Histidine kinase
DOFFCFEK_00753 3.1e-80 rbsB G sugar-binding domain protein
DOFFCFEK_00754 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
DOFFCFEK_00755 6.4e-116 manY G PTS system sorbose-specific iic component
DOFFCFEK_00756 4.7e-147 manN G system, mannose fructose sorbose family IID component
DOFFCFEK_00757 3.2e-52 manO S Domain of unknown function (DUF956)
DOFFCFEK_00758 5.1e-69 mltD CBM50 M NlpC P60 family protein
DOFFCFEK_00759 1.2e-128 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOFFCFEK_00760 2.6e-166 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFCFEK_00761 3.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
DOFFCFEK_00762 5.6e-46 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
DOFFCFEK_00763 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOFFCFEK_00764 1.9e-105 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOFFCFEK_00765 5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DOFFCFEK_00766 1.2e-46 S CRISPR-associated protein (Cas_Csn2)
DOFFCFEK_00767 8.1e-38 K transcriptional regulator PadR family
DOFFCFEK_00768 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
DOFFCFEK_00769 9e-16 S Putative adhesin
DOFFCFEK_00770 2.2e-16 pspC KT PspC domain
DOFFCFEK_00772 5.1e-13 S Enterocin A Immunity
DOFFCFEK_00773 6.8e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOFFCFEK_00774 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
DOFFCFEK_00775 2.1e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DOFFCFEK_00776 1.6e-165 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DOFFCFEK_00777 7.3e-120 potB P ABC transporter permease
DOFFCFEK_00778 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
DOFFCFEK_00779 1.7e-159 potD P ABC transporter
DOFFCFEK_00780 3.5e-132 ABC-SBP S ABC transporter
DOFFCFEK_00781 5.6e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DOFFCFEK_00782 2e-106 XK27_08845 S ABC transporter, ATP-binding protein
DOFFCFEK_00783 1.1e-67 M ErfK YbiS YcfS YnhG
DOFFCFEK_00784 1.6e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOFFCFEK_00785 5.5e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOFFCFEK_00786 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOFFCFEK_00787 2.2e-101 pgm3 G phosphoglycerate mutase
DOFFCFEK_00788 3e-55 S CAAX protease self-immunity
DOFFCFEK_00789 1.5e-47 C Flavodoxin
DOFFCFEK_00790 1e-45 yphJ 4.1.1.44 S decarboxylase
DOFFCFEK_00791 3.5e-144 E methionine synthase, vitamin-B12 independent
DOFFCFEK_00792 3e-84 drgA C nitroreductase
DOFFCFEK_00793 1.1e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
DOFFCFEK_00794 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
DOFFCFEK_00795 6.9e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DOFFCFEK_00796 2.5e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DOFFCFEK_00798 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOFFCFEK_00799 2.4e-31 metI U ABC transporter permease
DOFFCFEK_00800 9.6e-128 metQ M Belongs to the nlpA lipoprotein family
DOFFCFEK_00801 2.8e-54 S Protein of unknown function (DUF4256)
DOFFCFEK_00808 1.3e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DOFFCFEK_00809 2.1e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOFFCFEK_00810 2.2e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFFCFEK_00811 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DOFFCFEK_00812 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOFFCFEK_00814 1.6e-55 ctsR K Belongs to the CtsR family
DOFFCFEK_00815 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DOFFCFEK_00816 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFCFEK_00817 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFFCFEK_00818 4.3e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DOFFCFEK_00819 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOFFCFEK_00820 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOFFCFEK_00821 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOFFCFEK_00822 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DOFFCFEK_00823 1.5e-89 patB 4.4.1.8 E Aminotransferase, class I
DOFFCFEK_00824 1.6e-112 K response regulator
DOFFCFEK_00825 1.7e-141 hpk31 2.7.13.3 T Histidine kinase
DOFFCFEK_00826 7.2e-89 lacX 5.1.3.3 G Aldose 1-epimerase
DOFFCFEK_00827 3.5e-147 G Transporter, major facilitator family protein
DOFFCFEK_00828 3.5e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFFCFEK_00829 5.6e-246 yhcA V ABC transporter, ATP-binding protein
DOFFCFEK_00830 4.5e-35 K Bacterial regulatory proteins, tetR family
DOFFCFEK_00831 7.6e-223 lmrA V ABC transporter, ATP-binding protein
DOFFCFEK_00832 3.3e-253 yfiC V ABC transporter
DOFFCFEK_00834 5.4e-45 yjcF K protein acetylation
DOFFCFEK_00835 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
DOFFCFEK_00836 8.7e-72 lemA S LemA family
DOFFCFEK_00837 1.3e-114 htpX O Belongs to the peptidase M48B family
DOFFCFEK_00839 6.8e-272 helD 3.6.4.12 L DNA helicase
DOFFCFEK_00840 7.1e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOFFCFEK_00841 1.5e-170 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFFCFEK_00842 1.2e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DOFFCFEK_00843 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
DOFFCFEK_00844 9.2e-105 ybhR V ABC transporter
DOFFCFEK_00845 2.3e-31 K Transcriptional regulator
DOFFCFEK_00846 1.9e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
DOFFCFEK_00847 3.3e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DOFFCFEK_00848 1.2e-126
DOFFCFEK_00849 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOFFCFEK_00850 2e-103 tatD L hydrolase, TatD family
DOFFCFEK_00851 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOFFCFEK_00852 1.1e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOFFCFEK_00853 1.6e-22 veg S Biofilm formation stimulator VEG
DOFFCFEK_00854 4.9e-90 S Alpha/beta hydrolase of unknown function (DUF915)
DOFFCFEK_00855 1.6e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
DOFFCFEK_00856 6.6e-46 argR K Regulates arginine biosynthesis genes
DOFFCFEK_00857 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOFFCFEK_00858 2.7e-156 amtB P ammonium transporter
DOFFCFEK_00859 6.5e-201 argH 4.3.2.1 E argininosuccinate lyase
DOFFCFEK_00860 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DOFFCFEK_00861 1.7e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
DOFFCFEK_00862 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFCFEK_00863 1.2e-101 pfoS S Phosphotransferase system, EIIC
DOFFCFEK_00865 1.9e-69 rny D Peptidase family M23
DOFFCFEK_00866 3.1e-190 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
DOFFCFEK_00867 2.5e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
DOFFCFEK_00868 1.7e-114 M Core-2/I-Branching enzyme
DOFFCFEK_00869 5.9e-91 rfbP M Bacterial sugar transferase
DOFFCFEK_00870 3.1e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFFCFEK_00871 9.2e-112 ywqE 3.1.3.48 GM PHP domain protein
DOFFCFEK_00872 6.4e-83 ywqD 2.7.10.1 D Capsular exopolysaccharide family
DOFFCFEK_00873 1.6e-71 epsB M biosynthesis protein
DOFFCFEK_00874 9.7e-26 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
DOFFCFEK_00875 2.5e-101
DOFFCFEK_00876 2e-89 2.4.1.342 GT4 M Glycosyl transferases group 1
DOFFCFEK_00877 8e-93 M Glycosyl transferases group 1
DOFFCFEK_00878 3.1e-07 wzy S EpsG family
DOFFCFEK_00879 2.7e-66 wcmJ M Glycosyltransferase sugar-binding region containing DXD motif
DOFFCFEK_00880 4.8e-79 M Glycosyltransferase, group 2 family protein
DOFFCFEK_00881 3.8e-116 cps2J S Polysaccharide biosynthesis protein
DOFFCFEK_00882 2.7e-27 epsH S Hexapeptide repeat of succinyl-transferase
DOFFCFEK_00883 1e-108 M PFAM Glycosyl transferase, group 1
DOFFCFEK_00885 1e-111 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
DOFFCFEK_00886 2.2e-116 3.6.4.12 L UvrD/REP helicase N-terminal domain
DOFFCFEK_00887 1.1e-143 L AAA ATPase domain
DOFFCFEK_00888 9.7e-24 S response to antibiotic
DOFFCFEK_00889 4e-09 S response to antibiotic
DOFFCFEK_00890 6.6e-158 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DOFFCFEK_00891 2.3e-88 S Psort location CytoplasmicMembrane, score
DOFFCFEK_00892 1e-62 S Glycosyltransferase like family 2
DOFFCFEK_00893 1e-116 cps1D M Domain of unknown function (DUF4422)
DOFFCFEK_00894 3.9e-39 S CAAX protease self-immunity
DOFFCFEK_00895 1e-87 yvyE 3.4.13.9 S YigZ family
DOFFCFEK_00896 1e-58 S Haloacid dehalogenase-like hydrolase
DOFFCFEK_00897 5.8e-154 EGP Major facilitator Superfamily
DOFFCFEK_00899 3.1e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFFCFEK_00900 2.7e-27 K helix_turn_helix, mercury resistance
DOFFCFEK_00901 2.2e-90 S NADPH-dependent FMN reductase
DOFFCFEK_00902 7.5e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOFFCFEK_00903 5.5e-55 S ECF transporter, substrate-specific component
DOFFCFEK_00904 2.8e-95 znuB U ABC 3 transport family
DOFFCFEK_00905 3.8e-98 fhuC P ABC transporter
DOFFCFEK_00906 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
DOFFCFEK_00907 1.5e-38
DOFFCFEK_00908 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
DOFFCFEK_00909 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOFFCFEK_00910 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
DOFFCFEK_00911 1.1e-108 spo0J K Belongs to the ParB family
DOFFCFEK_00912 6.5e-118 soj D Sporulation initiation inhibitor
DOFFCFEK_00913 1.4e-81 noc K Belongs to the ParB family
DOFFCFEK_00914 1.1e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DOFFCFEK_00915 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DOFFCFEK_00916 1.2e-108 3.1.4.46 C phosphodiesterase
DOFFCFEK_00917 0.0 pacL 3.6.3.8 P P-type ATPase
DOFFCFEK_00918 2.3e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
DOFFCFEK_00919 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DOFFCFEK_00921 3.1e-63 srtA 3.4.22.70 M sortase family
DOFFCFEK_00922 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DOFFCFEK_00923 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DOFFCFEK_00925 2.9e-19
DOFFCFEK_00926 1.7e-86 pac DM Glucan-binding protein C
DOFFCFEK_00928 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
DOFFCFEK_00929 2.1e-22 S PIN domain
DOFFCFEK_00930 1.7e-33 3.1.21.3 V type I restriction modification DNA specificity domain
DOFFCFEK_00932 1.7e-68
DOFFCFEK_00933 6.8e-42 L Protein of unknown function (DUF3991)
DOFFCFEK_00934 1.9e-165 topA2 5.99.1.2 G Topoisomerase IA
DOFFCFEK_00937 2e-149 clpB O Belongs to the ClpA ClpB family
DOFFCFEK_00941 9.9e-220 U TraM recognition site of TraD and TraG
DOFFCFEK_00942 2.4e-77
DOFFCFEK_00944 1.7e-26
DOFFCFEK_00945 2e-192 U type IV secretory pathway VirB4
DOFFCFEK_00947 1.1e-29 M CHAP domain
DOFFCFEK_00950 6.5e-07
DOFFCFEK_00951 3.3e-62 sip L Belongs to the 'phage' integrase family
DOFFCFEK_00952 3.3e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DOFFCFEK_00953 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOFFCFEK_00954 6.2e-80 yvfR V ABC transporter
DOFFCFEK_00955 8.4e-54 yvfS V ABC-2 type transporter
DOFFCFEK_00956 2.4e-57 desK 2.7.13.3 T Histidine kinase
DOFFCFEK_00957 6.4e-76 desR K helix_turn_helix, Lux Regulon
DOFFCFEK_00958 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
DOFFCFEK_00959 1.5e-103 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
DOFFCFEK_00963 1.1e-142 xerS L Phage integrase family
DOFFCFEK_00964 6.5e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOFFCFEK_00965 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOFFCFEK_00966 6.1e-217 1.3.5.4 C FAD binding domain
DOFFCFEK_00967 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
DOFFCFEK_00968 4.7e-138 G Xylose isomerase-like TIM barrel
DOFFCFEK_00969 7.5e-73 K Transcriptional regulator, LysR family
DOFFCFEK_00970 2.2e-99 EGP Major Facilitator Superfamily
DOFFCFEK_00971 2.6e-129 EGP Major Facilitator Superfamily
DOFFCFEK_00972 1.5e-66 L Integrase core domain
DOFFCFEK_00974 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DOFFCFEK_00975 2.4e-31 P Heavy-metal-associated domain
DOFFCFEK_00976 3e-118 L transposase, IS605 OrfB family
DOFFCFEK_00977 2.9e-93 yihY S Belongs to the UPF0761 family
DOFFCFEK_00978 1.8e-11 mltD CBM50 M Lysin motif
DOFFCFEK_00979 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFFCFEK_00980 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
DOFFCFEK_00981 5.1e-54 fld C Flavodoxin
DOFFCFEK_00982 7.4e-52 gtcA S Teichoic acid glycosylation protein
DOFFCFEK_00983 0.0 S Bacterial membrane protein YfhO
DOFFCFEK_00984 3.1e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
DOFFCFEK_00985 1.7e-122 S Sulfite exporter TauE/SafE
DOFFCFEK_00986 1.5e-69 K Sugar-specific transcriptional regulator TrmB
DOFFCFEK_00987 1.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOFFCFEK_00988 2.3e-181 pepS E Thermophilic metalloprotease (M29)
DOFFCFEK_00989 1.4e-263 E Amino acid permease
DOFFCFEK_00990 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
DOFFCFEK_00991 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DOFFCFEK_00992 5e-78 galM 5.1.3.3 G Aldose 1-epimerase
DOFFCFEK_00993 4.3e-213 malT G Transporter, major facilitator family protein
DOFFCFEK_00994 6.1e-100 malR K Transcriptional regulator, LacI family
DOFFCFEK_00995 1e-279 kup P Transport of potassium into the cell
DOFFCFEK_00997 2e-20 S Domain of unknown function (DUF3284)
DOFFCFEK_00998 3.9e-160 yfmL L DEAD DEAH box helicase
DOFFCFEK_00999 1.2e-127 mocA S Oxidoreductase
DOFFCFEK_01000 3.4e-24 S Domain of unknown function (DUF4828)
DOFFCFEK_01001 5.6e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
DOFFCFEK_01002 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DOFFCFEK_01003 1e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
DOFFCFEK_01004 6.2e-120 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
DOFFCFEK_01005 1.1e-156 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DOFFCFEK_01006 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DOFFCFEK_01007 2.5e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DOFFCFEK_01008 9.9e-43 O ADP-ribosylglycohydrolase
DOFFCFEK_01009 4.2e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
DOFFCFEK_01010 7.6e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DOFFCFEK_01011 2.8e-34 K GNAT family
DOFFCFEK_01012 1.7e-40
DOFFCFEK_01014 1.6e-159 mgtE P Acts as a magnesium transporter
DOFFCFEK_01015 1.9e-92 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
DOFFCFEK_01016 3.8e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOFFCFEK_01017 9.4e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
DOFFCFEK_01018 7.6e-254 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
DOFFCFEK_01019 3.3e-36 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DOFFCFEK_01020 2.2e-193 pbuX F xanthine permease
DOFFCFEK_01021 4.1e-72 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOFFCFEK_01022 8.2e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
DOFFCFEK_01023 3.2e-64 S ECF transporter, substrate-specific component
DOFFCFEK_01024 2.5e-127 mleP S Sodium Bile acid symporter family
DOFFCFEK_01025 4.4e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
DOFFCFEK_01026 6.2e-72 mleR K LysR family
DOFFCFEK_01027 4.7e-57 K transcriptional
DOFFCFEK_01028 2.6e-41 K Bacterial regulatory proteins, tetR family
DOFFCFEK_01029 6.1e-60 T Belongs to the universal stress protein A family
DOFFCFEK_01030 1.2e-44 K Copper transport repressor CopY TcrY
DOFFCFEK_01031 1.9e-11 fhaB M translation initiation factor activity
DOFFCFEK_01032 4.6e-175 licA 2.7.1.89 M Choline/ethanolamine kinase
DOFFCFEK_01033 3.9e-85 M Nucleotidyl transferase
DOFFCFEK_01034 2e-150 M BCCT, betaine/carnitine/choline family transporter
DOFFCFEK_01035 3e-195 XK27_08315 M Sulfatase
DOFFCFEK_01037 3.5e-166 mdtG EGP Major facilitator Superfamily
DOFFCFEK_01038 4.4e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
DOFFCFEK_01039 3.1e-58 treR K UTRA
DOFFCFEK_01040 3.2e-215 treB G phosphotransferase system
DOFFCFEK_01041 1.6e-63 3.1.3.73 G phosphoglycerate mutase
DOFFCFEK_01042 2.4e-82 pncA Q isochorismatase
DOFFCFEK_01043 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DOFFCFEK_01044 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
DOFFCFEK_01045 6.4e-194 tnpB L Putative transposase DNA-binding domain
DOFFCFEK_01046 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOFFCFEK_01047 1.3e-41 K Transcriptional regulator, HxlR family
DOFFCFEK_01048 4.1e-163 C Luciferase-like monooxygenase
DOFFCFEK_01049 3.8e-67 1.5.1.38 S NADPH-dependent FMN reductase
DOFFCFEK_01050 2e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DOFFCFEK_01051 3.3e-75 L haloacid dehalogenase-like hydrolase
DOFFCFEK_01052 2.3e-61 EG EamA-like transporter family
DOFFCFEK_01053 3.4e-117 K AI-2E family transporter
DOFFCFEK_01054 3.8e-173 malY 4.4.1.8 E Aminotransferase, class I
DOFFCFEK_01055 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOFFCFEK_01056 1.3e-59 yfjR K WYL domain
DOFFCFEK_01059 6.7e-11 S Mor transcription activator family
DOFFCFEK_01060 7.1e-10 S zinc-ribbon domain
DOFFCFEK_01064 4.9e-92 V domain protein
DOFFCFEK_01065 1.7e-119 xth 3.1.11.2 L exodeoxyribonuclease III
DOFFCFEK_01066 2e-17
DOFFCFEK_01067 1.9e-104 azlC E AzlC protein
DOFFCFEK_01068 1.3e-38 azlD S branched-chain amino acid
DOFFCFEK_01069 5.6e-67 I alpha/beta hydrolase fold
DOFFCFEK_01070 6.8e-25
DOFFCFEK_01071 1.2e-58 3.6.1.27 I phosphatase
DOFFCFEK_01072 1.2e-22
DOFFCFEK_01073 3.4e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DOFFCFEK_01074 1.2e-88 sirR K Helix-turn-helix diphteria tox regulatory element
DOFFCFEK_01075 3.1e-27 cspC K Cold shock protein
DOFFCFEK_01076 4.3e-82 thrE S Putative threonine/serine exporter
DOFFCFEK_01077 6.3e-49 S Threonine/Serine exporter, ThrE
DOFFCFEK_01078 1.6e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFFCFEK_01079 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
DOFFCFEK_01080 1.9e-34 trxA O Belongs to the thioredoxin family
DOFFCFEK_01081 8e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFFCFEK_01082 3e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFFCFEK_01083 3.6e-64 degV S Uncharacterised protein, DegV family COG1307
DOFFCFEK_01085 4.3e-54 queT S QueT transporter
DOFFCFEK_01086 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
DOFFCFEK_01087 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
DOFFCFEK_01088 6.6e-175 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DOFFCFEK_01089 3.5e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOFFCFEK_01090 1.3e-87 S Alpha beta hydrolase
DOFFCFEK_01092 2.6e-08 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DOFFCFEK_01094 2.8e-26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFCFEK_01095 1.4e-32 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOFFCFEK_01096 1.8e-24 ytbE S reductase
DOFFCFEK_01097 1.5e-19 ytcD K HxlR-like helix-turn-helix
DOFFCFEK_01098 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
DOFFCFEK_01099 2e-67 ybbL S ABC transporter
DOFFCFEK_01100 1.4e-162 oxlT P Major Facilitator Superfamily
DOFFCFEK_01101 1.8e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOFFCFEK_01102 6.2e-11 L An automated process has identified a potential problem with this gene model
DOFFCFEK_01103 7e-181 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
DOFFCFEK_01104 4.4e-29 tetR K Transcriptional regulator C-terminal region
DOFFCFEK_01105 4.2e-151 yfeX P Peroxidase
DOFFCFEK_01106 6e-18 S Protein of unknown function (DUF3021)
DOFFCFEK_01107 4e-40 K LytTr DNA-binding domain
DOFFCFEK_01108 4e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
DOFFCFEK_01109 2.9e-209 mmuP E amino acid
DOFFCFEK_01110 2.7e-15 psiE S Phosphate-starvation-inducible E
DOFFCFEK_01111 1.3e-155 oppF P Belongs to the ABC transporter superfamily
DOFFCFEK_01112 1.3e-180 oppD P Belongs to the ABC transporter superfamily
DOFFCFEK_01113 2.6e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFCFEK_01114 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DOFFCFEK_01115 9e-202 oppA E ABC transporter, substratebinding protein
DOFFCFEK_01116 2.3e-217 yifK E Amino acid permease
DOFFCFEK_01117 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOFFCFEK_01118 5.1e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
DOFFCFEK_01119 6.5e-66 pgm3 G phosphoglycerate mutase family
DOFFCFEK_01120 2.3e-252 ctpA 3.6.3.54 P P-type ATPase
DOFFCFEK_01121 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOFFCFEK_01122 2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOFFCFEK_01123 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOFFCFEK_01124 8.7e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DOFFCFEK_01125 9.7e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DOFFCFEK_01126 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFFCFEK_01127 2.7e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
DOFFCFEK_01128 1e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
DOFFCFEK_01129 1.1e-23 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
DOFFCFEK_01130 9.8e-13 1.3.5.4 C FMN_bind
DOFFCFEK_01131 3.2e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
DOFFCFEK_01132 5.9e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
DOFFCFEK_01133 1.5e-75 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DOFFCFEK_01134 3.2e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
DOFFCFEK_01135 2.3e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOFFCFEK_01136 5.6e-82 S Belongs to the UPF0246 family
DOFFCFEK_01137 1e-11 S CAAX protease self-immunity
DOFFCFEK_01138 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
DOFFCFEK_01139 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOFFCFEK_01141 6.2e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOFFCFEK_01142 2e-63 C FMN binding
DOFFCFEK_01143 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOFFCFEK_01144 1.7e-54 rplI J Binds to the 23S rRNA
DOFFCFEK_01145 6.1e-264 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DOFFCFEK_01146 1.4e-06
DOFFCFEK_01148 1.3e-30 S Cell surface protein
DOFFCFEK_01150 6e-61 L Resolvase, N-terminal domain
DOFFCFEK_01151 1.1e-101 L Probable transposase
DOFFCFEK_01152 1.6e-180 pbuG S permease
DOFFCFEK_01153 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
DOFFCFEK_01154 2.2e-180 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOFFCFEK_01155 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOFFCFEK_01156 2.1e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOFFCFEK_01157 1.4e-145 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOFFCFEK_01158 5.4e-13
DOFFCFEK_01159 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
DOFFCFEK_01160 3.3e-91 yunF F Protein of unknown function DUF72
DOFFCFEK_01161 5e-156 nrnB S DHHA1 domain
DOFFCFEK_01162 2.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DOFFCFEK_01163 2.6e-60
DOFFCFEK_01164 1.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
DOFFCFEK_01165 2e-22 S Cytochrome B5
DOFFCFEK_01166 1.8e-19 sigH K DNA-templated transcription, initiation
DOFFCFEK_01167 1.5e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
DOFFCFEK_01168 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFFCFEK_01169 2.6e-97 ygaC J Belongs to the UPF0374 family
DOFFCFEK_01170 6.9e-92 yueF S AI-2E family transporter
DOFFCFEK_01171 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DOFFCFEK_01172 2.2e-111 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DOFFCFEK_01173 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOFFCFEK_01174 0.0 lacL 3.2.1.23 G -beta-galactosidase
DOFFCFEK_01175 4e-289 lacS G Transporter
DOFFCFEK_01176 5.9e-111 galR K Transcriptional regulator
DOFFCFEK_01177 7.7e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOFFCFEK_01178 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOFFCFEK_01179 1.1e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DOFFCFEK_01180 0.0 rafA 3.2.1.22 G alpha-galactosidase
DOFFCFEK_01181 1.5e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
DOFFCFEK_01182 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
DOFFCFEK_01183 0.0 clpE O Belongs to the ClpA ClpB family
DOFFCFEK_01184 1.5e-15
DOFFCFEK_01185 9.7e-37 ptsH G phosphocarrier protein HPR
DOFFCFEK_01186 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOFFCFEK_01187 5.2e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DOFFCFEK_01188 3.8e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
DOFFCFEK_01189 1.5e-125 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOFFCFEK_01190 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
DOFFCFEK_01191 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOFFCFEK_01193 3.2e-08
DOFFCFEK_01194 7.3e-13
DOFFCFEK_01199 1.9e-53 2.7.13.3 T GHKL domain
DOFFCFEK_01200 6.6e-57 K LytTr DNA-binding domain
DOFFCFEK_01206 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
DOFFCFEK_01207 2.8e-266 fbp 3.1.3.11 G phosphatase activity
DOFFCFEK_01208 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOFFCFEK_01209 7.2e-100 fabK 1.3.1.9 S Nitronate monooxygenase
DOFFCFEK_01210 3.1e-29 S Phage minor capsid protein 2
DOFFCFEK_01218 4.4e-71 M by MetaGeneAnnotator
DOFFCFEK_01220 7.4e-13 dnaG M by MetaGeneAnnotator
DOFFCFEK_01221 9.3e-117 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFCFEK_01222 7.3e-136 pfoS S Phosphotransferase system, EIIC
DOFFCFEK_01223 1.7e-256 V Type II restriction enzyme, methylase subunits
DOFFCFEK_01224 3.4e-225 E ABC transporter, substratebinding protein
DOFFCFEK_01225 3.1e-115 sufC O FeS assembly ATPase SufC
DOFFCFEK_01226 4.6e-145 sufD O FeS assembly protein SufD
DOFFCFEK_01227 3.7e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOFFCFEK_01228 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
DOFFCFEK_01229 4.2e-240 sufB O assembly protein SufB
DOFFCFEK_01230 3.3e-45 S VIT family
DOFFCFEK_01231 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DOFFCFEK_01232 2.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOFFCFEK_01233 2.3e-111 rssA S Phospholipase, patatin family
DOFFCFEK_01234 8.2e-16
DOFFCFEK_01235 3.5e-12 K Helix-turn-helix XRE-family like proteins
DOFFCFEK_01236 4.5e-10
DOFFCFEK_01237 5.3e-09 S Arc-like DNA binding domain
DOFFCFEK_01239 1.3e-20 S Replication initiator protein A (RepA) N-terminus
DOFFCFEK_01244 3.6e-07
DOFFCFEK_01246 5.2e-31 S Protein of unknown function (DUF3800)
DOFFCFEK_01247 4.9e-19
DOFFCFEK_01250 7.7e-28 aguA_2 3.5.3.12 E Belongs to the agmatine deiminase family
DOFFCFEK_01252 1.3e-40 wecD K Acetyltransferase GNAT Family
DOFFCFEK_01253 5.1e-47 hmpT S ECF-type riboflavin transporter, S component
DOFFCFEK_01254 3.3e-70 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DOFFCFEK_01257 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
DOFFCFEK_01258 1.4e-286 pepO 3.4.24.71 O Peptidase family M13
DOFFCFEK_01259 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
DOFFCFEK_01260 5.3e-54 K Transcriptional regulator C-terminal region
DOFFCFEK_01261 1.6e-55 jag S R3H domain protein
DOFFCFEK_01262 9e-57 ohrR K helix_turn_helix multiple antibiotic resistance protein
DOFFCFEK_01263 1.6e-33 azlD S Branched-chain amino acid transport protein (AzlD)
DOFFCFEK_01264 6.5e-62 azlC E branched-chain amino acid
DOFFCFEK_01266 2.1e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
DOFFCFEK_01267 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DOFFCFEK_01268 1e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
DOFFCFEK_01269 4.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFFCFEK_01270 2e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
DOFFCFEK_01271 4.1e-75 XK27_02070 S Nitroreductase family
DOFFCFEK_01272 4.9e-111 endA F DNA RNA non-specific endonuclease
DOFFCFEK_01274 2.5e-208 brnQ U Component of the transport system for branched-chain amino acids
DOFFCFEK_01275 5e-61 K Bacterial regulatory proteins, tetR family
DOFFCFEK_01276 3.5e-113 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DOFFCFEK_01277 4e-152 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DOFFCFEK_01278 4.3e-69 dhaL 2.7.1.121 S Dak2
DOFFCFEK_01279 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
DOFFCFEK_01280 3.8e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DOFFCFEK_01281 6.4e-176 yjcE P Sodium proton antiporter
DOFFCFEK_01282 2.8e-208 mtlR K Mga helix-turn-helix domain
DOFFCFEK_01283 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOFFCFEK_01284 1e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DOFFCFEK_01285 1.4e-44 M Glycosyl hydrolases family 25
DOFFCFEK_01287 4.5e-102 tcyB E ABC transporter
DOFFCFEK_01288 6e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFFCFEK_01289 9.8e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DOFFCFEK_01290 1.2e-38 K Transcriptional regulator
DOFFCFEK_01291 2.2e-107 terC P Integral membrane protein TerC family
DOFFCFEK_01292 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
DOFFCFEK_01293 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFFCFEK_01294 2.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
DOFFCFEK_01295 5.3e-41 gntR1 K Transcriptional regulator, GntR family
DOFFCFEK_01296 6.8e-95 V ABC transporter, ATP-binding protein
DOFFCFEK_01297 3.9e-09
DOFFCFEK_01298 1.1e-39 ybjQ S Belongs to the UPF0145 family
DOFFCFEK_01299 2.8e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOFFCFEK_01300 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOFFCFEK_01301 2.6e-156 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOFFCFEK_01302 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOFFCFEK_01303 1.4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFFCFEK_01304 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOFFCFEK_01305 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
DOFFCFEK_01306 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
DOFFCFEK_01307 6.3e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOFFCFEK_01308 3.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOFFCFEK_01309 1.6e-108 ymfF S Peptidase M16 inactive domain protein
DOFFCFEK_01310 9.3e-149 ymfH S Peptidase M16
DOFFCFEK_01311 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
DOFFCFEK_01312 2.9e-64 ymfM S Helix-turn-helix domain
DOFFCFEK_01313 4.7e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOFFCFEK_01314 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOFFCFEK_01315 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
DOFFCFEK_01316 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOFFCFEK_01317 2.2e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOFFCFEK_01318 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOFFCFEK_01319 8.2e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOFFCFEK_01320 7.9e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DOFFCFEK_01321 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DOFFCFEK_01322 1.4e-12 yajC U Preprotein translocase
DOFFCFEK_01324 4.3e-61 uspA T universal stress protein
DOFFCFEK_01326 7.4e-208 yfnA E Amino Acid
DOFFCFEK_01327 6.9e-117 lutA C Cysteine-rich domain
DOFFCFEK_01328 2.1e-245 lutB C 4Fe-4S dicluster domain
DOFFCFEK_01329 3.2e-66 yrjD S LUD domain
DOFFCFEK_01330 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFFCFEK_01331 7.5e-13
DOFFCFEK_01332 1.2e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DOFFCFEK_01333 5.6e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOFFCFEK_01334 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOFFCFEK_01335 2.1e-36 yrzL S Belongs to the UPF0297 family
DOFFCFEK_01336 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOFFCFEK_01337 1.9e-33 yrzB S Belongs to the UPF0473 family
DOFFCFEK_01338 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DOFFCFEK_01339 2.1e-17 cvpA S Colicin V production protein
DOFFCFEK_01340 4e-307 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOFFCFEK_01341 7.6e-41 trxA O Belongs to the thioredoxin family
DOFFCFEK_01344 8.8e-36
DOFFCFEK_01345 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOFFCFEK_01346 4.2e-61 marR K Transcriptional regulator, MarR family
DOFFCFEK_01347 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOFFCFEK_01348 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOFFCFEK_01349 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DOFFCFEK_01350 1.3e-99 IQ reductase
DOFFCFEK_01351 6.2e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOFFCFEK_01352 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOFFCFEK_01353 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOFFCFEK_01354 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
DOFFCFEK_01355 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOFFCFEK_01356 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
DOFFCFEK_01357 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DOFFCFEK_01358 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOFFCFEK_01359 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
DOFFCFEK_01360 3.2e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOFFCFEK_01361 5.7e-119 gla U Major intrinsic protein
DOFFCFEK_01362 5.8e-45 ykuL S CBS domain
DOFFCFEK_01363 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOFFCFEK_01364 1.6e-176 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOFFCFEK_01365 9e-87 ykuT M mechanosensitive ion channel
DOFFCFEK_01367 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOFFCFEK_01368 2e-21 yheA S Belongs to the UPF0342 family
DOFFCFEK_01369 3.3e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFFCFEK_01370 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOFFCFEK_01372 7e-53 hit FG histidine triad
DOFFCFEK_01373 7.5e-95 ecsA V ABC transporter, ATP-binding protein
DOFFCFEK_01374 9.9e-73 ecsB U ABC transporter
DOFFCFEK_01375 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
DOFFCFEK_01376 1.5e-99 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOFFCFEK_01377 4.9e-43 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOFFCFEK_01378 1.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFFCFEK_01379 1.5e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
DOFFCFEK_01380 4.9e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DOFFCFEK_01381 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
DOFFCFEK_01382 3.9e-69 ybhL S Belongs to the BI1 family
DOFFCFEK_01384 6.3e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
DOFFCFEK_01385 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DOFFCFEK_01386 3.8e-69 coiA 3.6.4.12 S Competence protein
DOFFCFEK_01387 2.5e-232 pepF E oligoendopeptidase F
DOFFCFEK_01388 1.3e-41 yjbH Q Thioredoxin
DOFFCFEK_01389 1.1e-97 pstS P Phosphate
DOFFCFEK_01390 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
DOFFCFEK_01391 1.3e-122 pstA P Phosphate transport system permease protein PstA
DOFFCFEK_01392 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFFCFEK_01393 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFFCFEK_01394 2.7e-56 P Plays a role in the regulation of phosphate uptake
DOFFCFEK_01395 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DOFFCFEK_01396 3.2e-79 S VIT family
DOFFCFEK_01397 9.4e-84 S membrane
DOFFCFEK_01398 3.6e-40 M1-874 K Domain of unknown function (DUF1836)
DOFFCFEK_01399 2.3e-65 hly S protein, hemolysin III
DOFFCFEK_01400 6.9e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFFCFEK_01401 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFFCFEK_01404 2e-13
DOFFCFEK_01405 1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOFFCFEK_01406 1.3e-158 ccpA K catabolite control protein A
DOFFCFEK_01407 3.7e-42 S VanZ like family
DOFFCFEK_01408 1.5e-119 yebC K Transcriptional regulatory protein
DOFFCFEK_01409 1.8e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOFFCFEK_01410 1.1e-120 comGA NU Type II IV secretion system protein
DOFFCFEK_01411 4.4e-98 comGB NU type II secretion system
DOFFCFEK_01412 3.6e-27 comGC U competence protein ComGC
DOFFCFEK_01413 1.1e-13
DOFFCFEK_01415 9.4e-11 S Putative Competence protein ComGF
DOFFCFEK_01417 2e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
DOFFCFEK_01418 9.3e-184 cycA E Amino acid permease
DOFFCFEK_01419 7.8e-58 S Calcineurin-like phosphoesterase
DOFFCFEK_01420 2.5e-53 yutD S Protein of unknown function (DUF1027)
DOFFCFEK_01421 4.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOFFCFEK_01422 1.7e-31 S Protein of unknown function (DUF1461)
DOFFCFEK_01423 3e-92 dedA S SNARE associated Golgi protein
DOFFCFEK_01424 3.6e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DOFFCFEK_01425 8.8e-50 yugI 5.3.1.9 J general stress protein
DOFFCFEK_01426 2.5e-153 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DOFFCFEK_01427 7.6e-41 cpsJ S Glycosyltransferase like family 2
DOFFCFEK_01428 1.8e-42 M Glycosyl transferase, family 2 glycosyl transferase family 8
DOFFCFEK_01429 5.8e-41 cpsJ S Glycosyltransferase like family 2
DOFFCFEK_01430 1.2e-38 M family 8
DOFFCFEK_01431 8.2e-35 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
DOFFCFEK_01432 1.9e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DOFFCFEK_01433 2.1e-55 M lipopolysaccharide 3-alpha-galactosyltransferase activity
DOFFCFEK_01434 9.5e-69 nss M transferase activity, transferring glycosyl groups
DOFFCFEK_01435 1e-43 arbx M family 8
DOFFCFEK_01437 2.1e-43 nss M transferase activity, transferring glycosyl groups
DOFFCFEK_01438 3.5e-52 nss M transferase activity, transferring glycosyl groups
DOFFCFEK_01439 2.5e-36 M family 8
DOFFCFEK_01440 1.8e-37 M family 8
DOFFCFEK_01441 3e-70 nss M transferase activity, transferring glycosyl groups
DOFFCFEK_01442 3.1e-31 M Glycosyltransferase like family 2
DOFFCFEK_01443 5.2e-48 arbx M family 8
DOFFCFEK_01444 1.4e-147 mepA V MATE efflux family protein
DOFFCFEK_01445 6.2e-149 lsa S ABC transporter
DOFFCFEK_01446 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOFFCFEK_01447 8e-110 puuD S peptidase C26
DOFFCFEK_01448 1.9e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
DOFFCFEK_01449 1.1e-25
DOFFCFEK_01450 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
DOFFCFEK_01451 1.1e-59 uspA T Universal stress protein family
DOFFCFEK_01453 7.3e-211 glnP P ABC transporter
DOFFCFEK_01454 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DOFFCFEK_01455 0.0 L SNF2 family N-terminal domain
DOFFCFEK_01457 7.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
DOFFCFEK_01458 1e-22
DOFFCFEK_01459 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
DOFFCFEK_01461 9.9e-87 S overlaps another CDS with the same product name
DOFFCFEK_01462 1.8e-124 S overlaps another CDS with the same product name
DOFFCFEK_01463 7.7e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOFFCFEK_01464 2e-62 ytkL S Belongs to the UPF0173 family
DOFFCFEK_01465 1.4e-290 ybiT S ABC transporter, ATP-binding protein
DOFFCFEK_01466 5.6e-77 2.4.2.3 F Phosphorylase superfamily
DOFFCFEK_01467 1.7e-24
DOFFCFEK_01468 1.2e-112 dkg S reductase
DOFFCFEK_01469 5.3e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOFFCFEK_01470 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOFFCFEK_01471 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOFFCFEK_01472 2.4e-37 EGP Transmembrane secretion effector
DOFFCFEK_01473 5.2e-137 purR 2.4.2.7 F pur operon repressor
DOFFCFEK_01474 2.7e-28 adhR K helix_turn_helix, mercury resistance
DOFFCFEK_01475 5.1e-13 adhR K helix_turn_helix, mercury resistance
DOFFCFEK_01476 5.2e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOFFCFEK_01477 2e-19 M domain protein
DOFFCFEK_01478 5.2e-21 K helix_turn_helix multiple antibiotic resistance protein
DOFFCFEK_01479 4.4e-165 EGP Major facilitator Superfamily
DOFFCFEK_01480 4.7e-81 S L,D-transpeptidase catalytic domain
DOFFCFEK_01481 2.3e-140 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DOFFCFEK_01482 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOFFCFEK_01483 3.6e-26 ydiI Q Thioesterase superfamily
DOFFCFEK_01484 9.5e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
DOFFCFEK_01485 9.6e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
DOFFCFEK_01486 8.4e-114 degV S EDD domain protein, DegV family
DOFFCFEK_01487 2.6e-226 cadA P P-type ATPase
DOFFCFEK_01488 2.4e-254 E Amino acid permease
DOFFCFEK_01489 2.7e-83 S Membrane
DOFFCFEK_01490 7.3e-23 cps3F
DOFFCFEK_01491 3.6e-19 cps3F
DOFFCFEK_01492 1.1e-302 fruA 2.7.1.202 GT Phosphotransferase System
DOFFCFEK_01493 2.4e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DOFFCFEK_01494 9e-88 fruR K DeoR C terminal sensor domain
DOFFCFEK_01495 3.9e-219 XK27_08635 S UPF0210 protein
DOFFCFEK_01496 4.1e-27 gcvR T Belongs to the UPF0237 family
DOFFCFEK_01497 6.1e-39
DOFFCFEK_01498 4.8e-77 E GDSL-like Lipase/Acylhydrolase family
DOFFCFEK_01499 7.1e-56 S Protein of unknown function (DUF975)
DOFFCFEK_01500 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
DOFFCFEK_01501 3e-230 lpdA 1.8.1.4 C Dehydrogenase
DOFFCFEK_01502 6.9e-181 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOFFCFEK_01503 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
DOFFCFEK_01504 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DOFFCFEK_01505 8.5e-19 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
DOFFCFEK_01506 2.9e-15 GM domain, Protein
DOFFCFEK_01507 5.5e-09 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
DOFFCFEK_01508 7.5e-36 K Psort location Cytoplasmic, score 8.87
DOFFCFEK_01509 3.9e-126 O regulation of methylation-dependent chromatin silencing
DOFFCFEK_01510 4.5e-22 K Cro/C1-type HTH DNA-binding domain
DOFFCFEK_01511 1.8e-18 ebh D nuclear chromosome segregation
DOFFCFEK_01513 4.4e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
DOFFCFEK_01514 6e-296 S membrane
DOFFCFEK_01515 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOFFCFEK_01516 3.4e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
DOFFCFEK_01517 2.6e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
DOFFCFEK_01518 1.2e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOFFCFEK_01520 7e-16
DOFFCFEK_01521 5.6e-200 oatA I Acyltransferase
DOFFCFEK_01522 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOFFCFEK_01523 1.1e-304 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOFFCFEK_01524 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFFCFEK_01527 1.5e-41 S Phosphoesterase
DOFFCFEK_01528 1.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOFFCFEK_01529 1.1e-60 yslB S Protein of unknown function (DUF2507)
DOFFCFEK_01530 1.1e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
DOFFCFEK_01531 1.8e-09 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
DOFFCFEK_01533 5.6e-59 dps P Ferritin-like domain
DOFFCFEK_01534 1.7e-199 tnpB L Putative transposase DNA-binding domain
DOFFCFEK_01535 2.3e-45 L Resolvase, N-terminal
DOFFCFEK_01536 2.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
DOFFCFEK_01537 2.3e-11 S YjcQ protein
DOFFCFEK_01539 9e-102 qmcA O prohibitin homologues
DOFFCFEK_01540 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
DOFFCFEK_01541 0.0 O Belongs to the peptidase S8 family
DOFFCFEK_01542 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOFFCFEK_01543 2.9e-36 S Enterocin A Immunity
DOFFCFEK_01544 4.9e-82 yitS S EDD domain protein, DegV family
DOFFCFEK_01545 1.6e-56 racA K Domain of unknown function (DUF1836)
DOFFCFEK_01546 4.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DOFFCFEK_01547 4.1e-85 potE2 E amino acid
DOFFCFEK_01550 9.1e-90 rlmI 2.1.1.191, 2.1.1.37, 2.1.1.72 L C-5 cytosine-specific DNA methylase
DOFFCFEK_01551 2.8e-127 dcm 2.1.1.37, 2.1.1.72 H Adenine-specific methyltransferase EcoRI
DOFFCFEK_01552 6.8e-45 S HNH endonuclease
DOFFCFEK_01554 7.8e-61 hsdM 2.1.1.72 V type I restriction-modification system
DOFFCFEK_01555 1.9e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
DOFFCFEK_01556 5.4e-71 L Belongs to the 'phage' integrase family
DOFFCFEK_01557 6.9e-37
DOFFCFEK_01558 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOFFCFEK_01559 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
DOFFCFEK_01560 1.5e-27 yazA L GIY-YIG catalytic domain protein
DOFFCFEK_01561 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
DOFFCFEK_01562 2e-88 plsC 2.3.1.51 I Acyltransferase
DOFFCFEK_01563 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DOFFCFEK_01564 1.5e-55 yceD S Uncharacterized ACR, COG1399
DOFFCFEK_01565 4.5e-123 ylbM S Belongs to the UPF0348 family
DOFFCFEK_01566 9.4e-82 yqeM Q Methyltransferase
DOFFCFEK_01567 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOFFCFEK_01568 6.7e-70 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DOFFCFEK_01569 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOFFCFEK_01570 6e-30 yhbY J RNA-binding protein
DOFFCFEK_01571 3.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
DOFFCFEK_01572 1.2e-70 yqeG S HAD phosphatase, family IIIA
DOFFCFEK_01573 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOFFCFEK_01574 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DOFFCFEK_01575 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOFFCFEK_01576 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOFFCFEK_01577 3.3e-108 dnaI L Primosomal protein DnaI
DOFFCFEK_01578 3.6e-79 dnaB L replication initiation and membrane attachment
DOFFCFEK_01579 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOFFCFEK_01580 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOFFCFEK_01581 1.2e-106 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOFFCFEK_01582 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOFFCFEK_01583 3.3e-165 XK27_08315 M Sulfatase
DOFFCFEK_01584 4.4e-87 M Dolichyl-phosphate-mannose-protein mannosyltransferase
DOFFCFEK_01585 1e-13
DOFFCFEK_01586 7.2e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DOFFCFEK_01587 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
DOFFCFEK_01588 7e-157 XK27_09615 S reductase
DOFFCFEK_01589 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
DOFFCFEK_01590 7.3e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOFFCFEK_01591 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DOFFCFEK_01592 4e-310 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DOFFCFEK_01593 2.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DOFFCFEK_01594 1.5e-132 coaA 2.7.1.33 F Pantothenic acid kinase
DOFFCFEK_01595 6.3e-44 E lipolytic protein G-D-S-L family
DOFFCFEK_01596 6.1e-113 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFFCFEK_01597 3.6e-189 glnPH2 P ABC transporter permease
DOFFCFEK_01598 2.9e-152 mdtG EGP Major facilitator Superfamily
DOFFCFEK_01599 5e-14 yobS K transcriptional regulator
DOFFCFEK_01600 6.2e-109 glcU U sugar transport
DOFFCFEK_01601 3.4e-170 yjjP S Putative threonine/serine exporter
DOFFCFEK_01602 3.1e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
DOFFCFEK_01603 1.7e-96 yicL EG EamA-like transporter family
DOFFCFEK_01604 9.3e-224 pepF E Oligopeptidase F
DOFFCFEK_01605 1.2e-107 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFFCFEK_01606 1.2e-179 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOFFCFEK_01607 7.9e-22 S dextransucrase activity
DOFFCFEK_01608 5.6e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
DOFFCFEK_01609 1.5e-63 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DOFFCFEK_01611 5.6e-13 S Bacterial toxin of type II toxin-antitoxin system, YafQ
DOFFCFEK_01612 3.1e-174 S Putative peptidoglycan binding domain
DOFFCFEK_01613 2.1e-31 K Transcriptional regulator, MarR family
DOFFCFEK_01614 1.7e-211 XK27_09600 V ABC transporter, ATP-binding protein
DOFFCFEK_01615 6.4e-241 V ABC transporter transmembrane region
DOFFCFEK_01616 2.8e-168 uhpT EGP Mycoplasma MFS transporter
DOFFCFEK_01617 2.7e-157 lctO C FMN-dependent dehydrogenase
DOFFCFEK_01618 3.6e-106 yxeH S hydrolase
DOFFCFEK_01619 9e-114 K response regulator
DOFFCFEK_01620 6.2e-271 vicK 2.7.13.3 T Histidine kinase
DOFFCFEK_01621 1e-102 yycH S YycH protein
DOFFCFEK_01622 1.9e-80 yycI S YycH protein
DOFFCFEK_01623 3.4e-31 tlpA2 L Transposase IS200 like
DOFFCFEK_01624 3.6e-187 mtnE 2.6.1.83 E Aminotransferase
DOFFCFEK_01625 4.5e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
DOFFCFEK_01626 3.4e-67 S Protein of unknown function (DUF1440)
DOFFCFEK_01627 7.7e-41 S Iron-sulfur cluster assembly protein
DOFFCFEK_01628 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DOFFCFEK_01629 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DOFFCFEK_01630 2.9e-219 3.2.1.18, 3.2.1.4 GH33,GH5,GH9 G BNR repeat-like domain
DOFFCFEK_01631 8.8e-201 gph G MFS/sugar transport protein
DOFFCFEK_01632 8.7e-180 yjhC S Semialdehyde dehydrogenase, NAD binding domain
DOFFCFEK_01633 3.7e-36 G single-species biofilm formation
DOFFCFEK_01634 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
DOFFCFEK_01635 6.5e-90 nanK GK ROK family
DOFFCFEK_01636 1.8e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
DOFFCFEK_01637 1.6e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DOFFCFEK_01638 2.3e-76 K Helix-turn-helix domain, rpiR family
DOFFCFEK_01639 5.5e-59 yphA GM NAD dependent epimerase/dehydratase family
DOFFCFEK_01640 3e-145 yjeM E Amino Acid
DOFFCFEK_01641 2.4e-248 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
DOFFCFEK_01642 8.2e-61
DOFFCFEK_01643 3.6e-41 rpmE2 J Ribosomal protein L31
DOFFCFEK_01644 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DOFFCFEK_01645 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOFFCFEK_01647 4.7e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOFFCFEK_01648 9.8e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOFFCFEK_01649 1.8e-32 ywiB S Domain of unknown function (DUF1934)
DOFFCFEK_01650 3.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
DOFFCFEK_01651 2.5e-205 ywfO S HD domain protein
DOFFCFEK_01652 3.1e-89 S hydrolase
DOFFCFEK_01653 3.8e-104 ydcZ S Putative inner membrane exporter, YdcZ
DOFFCFEK_01654 2.2e-27
DOFFCFEK_01655 3.3e-59
DOFFCFEK_01656 1.1e-70 L recombinase activity
DOFFCFEK_01658 7.8e-247 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOFFCFEK_01659 9.5e-31 asp3 S Accessory Sec system protein Asp3
DOFFCFEK_01660 3.5e-102 asp2 3.4.11.5 S Accessory Sec system protein Asp2
DOFFCFEK_01661 5.8e-84 asp1 S Accessory Sec system protein Asp1
DOFFCFEK_01662 7.8e-65 secY2 U SecY translocase
DOFFCFEK_01663 2.5e-134 S interspecies interaction between organisms
DOFFCFEK_01664 7.2e-208 G glycerol-3-phosphate transporter
DOFFCFEK_01665 7.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOFFCFEK_01666 5.6e-146 htrA 3.4.21.107 O serine protease
DOFFCFEK_01667 2e-117 vicX 3.1.26.11 S domain protein
DOFFCFEK_01668 2.8e-26 ebh 2.1.1.80, 3.1.1.61 D interspecies interaction between organisms
DOFFCFEK_01669 0.0 L Type III restriction enzyme, res subunit
DOFFCFEK_01670 1.5e-60 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
DOFFCFEK_01671 8.2e-63 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
DOFFCFEK_01672 2.5e-192 pepV 3.5.1.18 E dipeptidase PepV
DOFFCFEK_01673 3.2e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOFFCFEK_01674 2.8e-62 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFFCFEK_01675 6.4e-187 ytgP S Polysaccharide biosynthesis protein
DOFFCFEK_01676 2.4e-192 cycA E Amino acid permease
DOFFCFEK_01677 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFFCFEK_01678 3.7e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOFFCFEK_01681 9.4e-109 L Initiator Replication protein
DOFFCFEK_01682 5.1e-38 S Replication initiator protein A (RepA) N-terminus
DOFFCFEK_01683 1.7e-167 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFFCFEK_01684 9.8e-86 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DOFFCFEK_01685 3.3e-15 bglG K antiterminator
DOFFCFEK_01686 2.8e-216 L Probable transposase
DOFFCFEK_01687 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
DOFFCFEK_01689 2.4e-183 L Probable transposase
DOFFCFEK_01690 1.6e-28
DOFFCFEK_01691 0.0 pepN 3.4.11.2 E aminopeptidase
DOFFCFEK_01694 1.8e-124 yvgN C Aldo keto reductase
DOFFCFEK_01695 4.6e-55 yvbG U MarC family integral membrane protein
DOFFCFEK_01697 1.9e-96 MA20_14895 S Conserved hypothetical protein 698
DOFFCFEK_01698 1.1e-199 nupG F Nucleoside
DOFFCFEK_01699 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFFCFEK_01700 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOFFCFEK_01701 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DOFFCFEK_01702 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOFFCFEK_01703 6.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOFFCFEK_01704 1.2e-19 yaaA S S4 domain protein YaaA
DOFFCFEK_01705 1.1e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOFFCFEK_01706 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFFCFEK_01707 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFFCFEK_01711 5.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOFFCFEK_01712 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DOFFCFEK_01713 1.7e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOFFCFEK_01714 7.9e-160 camS S sex pheromone
DOFFCFEK_01715 1.7e-37 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFFCFEK_01716 5.2e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOFFCFEK_01717 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFFCFEK_01718 9.8e-146 yegS 2.7.1.107 G Lipid kinase
DOFFCFEK_01719 6.2e-212 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFFCFEK_01720 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOFFCFEK_01721 2.7e-129 mleP2 S Sodium Bile acid symporter family
DOFFCFEK_01722 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOFFCFEK_01724 3e-43 ydcK S Belongs to the SprT family
DOFFCFEK_01725 5.7e-252 yhgF K Tex-like protein N-terminal domain protein
DOFFCFEK_01726 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOFFCFEK_01727 7.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOFFCFEK_01728 1.2e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DOFFCFEK_01729 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
DOFFCFEK_01730 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOFFCFEK_01732 1.1e-07
DOFFCFEK_01733 1.6e-197 dtpT U amino acid peptide transporter
DOFFCFEK_01734 6e-226 pipD E Dipeptidase
DOFFCFEK_01735 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFFCFEK_01736 2.6e-32 ywjH S Protein of unknown function (DUF1634)
DOFFCFEK_01737 1.7e-119 yxaA S membrane transporter protein
DOFFCFEK_01738 2.2e-82 lysR5 K LysR substrate binding domain
DOFFCFEK_01739 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
DOFFCFEK_01740 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DOFFCFEK_01741 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DOFFCFEK_01742 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
DOFFCFEK_01743 1.9e-243 lysP E amino acid
DOFFCFEK_01744 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOFFCFEK_01745 3.6e-116 S Glycosyl transferase family 2
DOFFCFEK_01746 6.7e-65 D peptidase
DOFFCFEK_01747 0.0 asnB 6.3.5.4 E Asparagine synthase
DOFFCFEK_01748 3.3e-41 yiiE S Protein of unknown function (DUF1211)
DOFFCFEK_01749 2.1e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DOFFCFEK_01750 1.8e-246 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DOFFCFEK_01751 5.7e-18 yneR
DOFFCFEK_01752 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOFFCFEK_01753 1.6e-222 yxbA 6.3.1.12 S ATP-grasp enzyme
DOFFCFEK_01754 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DOFFCFEK_01755 6.2e-99 ypuA S Protein of unknown function (DUF1002)
DOFFCFEK_01756 7.6e-61 dedA 3.1.3.1 S SNARE associated Golgi protein
DOFFCFEK_01757 4.4e-161 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFFCFEK_01758 2e-18 yncA 2.3.1.79 S Maltose acetyltransferase
DOFFCFEK_01759 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
DOFFCFEK_01760 3.2e-200 frdC 1.3.5.4 C FAD binding domain
DOFFCFEK_01761 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DOFFCFEK_01762 2e-14 ybaN S Protein of unknown function (DUF454)
DOFFCFEK_01763 4e-32 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DOFFCFEK_01764 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
DOFFCFEK_01765 1.4e-181 gatC G PTS system sugar-specific permease component
DOFFCFEK_01766 1.6e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
DOFFCFEK_01767 7.4e-168 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
DOFFCFEK_01768 6e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DOFFCFEK_01769 1.8e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DOFFCFEK_01770 4e-233 tetP J elongation factor G
DOFFCFEK_01771 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOFFCFEK_01773 1.5e-52 yjeM E Amino Acid
DOFFCFEK_01774 5.7e-20 MA20_14895 S Conserved hypothetical protein 698
DOFFCFEK_01775 1.7e-53 K LysR substrate binding domain
DOFFCFEK_01776 8.1e-08
DOFFCFEK_01777 1.8e-65 yxkH G Polysaccharide deacetylase
DOFFCFEK_01778 9e-30 yqkB S Belongs to the HesB IscA family
DOFFCFEK_01779 5.5e-214 yjeM E Amino Acid
DOFFCFEK_01780 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
DOFFCFEK_01781 1.8e-135 tetA EGP Major facilitator Superfamily
DOFFCFEK_01782 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOFFCFEK_01783 7.7e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOFFCFEK_01784 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
DOFFCFEK_01785 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOFFCFEK_01786 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOFFCFEK_01787 2.1e-109 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)