ORF_ID e_value Gene_name EC_number CAZy COGs Description
GHMDDCDL_00001 7.4e-94
GHMDDCDL_00002 5.9e-267 M domain protein
GHMDDCDL_00003 2.8e-118 M domain protein
GHMDDCDL_00004 2.8e-81 M domain protein
GHMDDCDL_00005 2.5e-32
GHMDDCDL_00006 1.2e-183 ampC V Beta-lactamase
GHMDDCDL_00007 8.9e-218 arcA 3.5.3.6 E Arginine
GHMDDCDL_00008 2.7e-79 argR K Regulates arginine biosynthesis genes
GHMDDCDL_00009 1.1e-259 E Arginine ornithine antiporter
GHMDDCDL_00010 1.8e-222 arcD U Amino acid permease
GHMDDCDL_00011 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
GHMDDCDL_00012 5.8e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
GHMDDCDL_00013 6e-108 tdk 2.7.1.21 F thymidine kinase
GHMDDCDL_00014 4.6e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHMDDCDL_00015 9.5e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GHMDDCDL_00016 3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GHMDDCDL_00017 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GHMDDCDL_00018 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GHMDDCDL_00019 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHMDDCDL_00020 1.9e-190 yibE S overlaps another CDS with the same product name
GHMDDCDL_00021 2.6e-130 yibF S overlaps another CDS with the same product name
GHMDDCDL_00022 3.8e-232 pyrP F Permease
GHMDDCDL_00023 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
GHMDDCDL_00024 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHMDDCDL_00025 2.9e-53 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GHMDDCDL_00026 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHMDDCDL_00027 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GHMDDCDL_00028 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHMDDCDL_00029 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GHMDDCDL_00030 3.8e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GHMDDCDL_00031 1.3e-33 ywzB S Protein of unknown function (DUF1146)
GHMDDCDL_00032 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHMDDCDL_00033 1.9e-178 mbl D Cell shape determining protein MreB Mrl
GHMDDCDL_00034 1e-31 S Protein of unknown function (DUF2969)
GHMDDCDL_00035 1.1e-220 rodA D Belongs to the SEDS family
GHMDDCDL_00036 1.4e-47 gcvH E glycine cleavage
GHMDDCDL_00037 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GHMDDCDL_00038 3.7e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00039 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GHMDDCDL_00040 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
GHMDDCDL_00041 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GHMDDCDL_00042 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GHMDDCDL_00043 1.1e-36 maa 2.3.1.79 S Maltose O-acetyltransferase
GHMDDCDL_00044 1.1e-45 maa 2.3.1.79 S Maltose O-acetyltransferase
GHMDDCDL_00045 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
GHMDDCDL_00046 2e-205 araR K Transcriptional regulator
GHMDDCDL_00047 4.3e-83 usp6 T universal stress protein
GHMDDCDL_00048 4.4e-46
GHMDDCDL_00049 8.5e-235 rarA L recombination factor protein RarA
GHMDDCDL_00050 2.7e-85 yueI S Protein of unknown function (DUF1694)
GHMDDCDL_00051 4.5e-21
GHMDDCDL_00052 8.1e-75 4.4.1.5 E Glyoxalase
GHMDDCDL_00053 2.5e-138 S Membrane
GHMDDCDL_00054 1e-139 S Belongs to the UPF0246 family
GHMDDCDL_00055 4.5e-186 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GHMDDCDL_00056 1.1e-33 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GHMDDCDL_00057 1.5e-32 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GHMDDCDL_00058 2.5e-258 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHMDDCDL_00059 1.1e-234 pbuG S permease
GHMDDCDL_00060 1.3e-276 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
GHMDDCDL_00061 2.8e-253 gadC E amino acid
GHMDDCDL_00062 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GHMDDCDL_00063 1.1e-237 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GHMDDCDL_00064 2.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
GHMDDCDL_00065 9.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHMDDCDL_00066 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GHMDDCDL_00067 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
GHMDDCDL_00068 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GHMDDCDL_00069 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GHMDDCDL_00070 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GHMDDCDL_00071 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
GHMDDCDL_00072 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHMDDCDL_00073 8e-122 radC L DNA repair protein
GHMDDCDL_00074 1.7e-179 mreB D cell shape determining protein MreB
GHMDDCDL_00075 3.5e-152 mreC M Involved in formation and maintenance of cell shape
GHMDDCDL_00076 8.7e-93 mreD M rod shape-determining protein MreD
GHMDDCDL_00077 3.2e-102 glnP P ABC transporter permease
GHMDDCDL_00078 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHMDDCDL_00079 1.7e-159 aatB ET ABC transporter substrate-binding protein
GHMDDCDL_00080 1.5e-225 ymfF S Peptidase M16 inactive domain protein
GHMDDCDL_00081 3e-248 ymfH S Peptidase M16
GHMDDCDL_00082 5e-137 ymfM S Helix-turn-helix domain
GHMDDCDL_00083 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHMDDCDL_00084 8.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
GHMDDCDL_00085 1.7e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GHMDDCDL_00086 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
GHMDDCDL_00087 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GHMDDCDL_00088 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GHMDDCDL_00089 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GHMDDCDL_00090 1.1e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GHMDDCDL_00091 5e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GHMDDCDL_00092 6.2e-31 yajC U Preprotein translocase
GHMDDCDL_00093 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GHMDDCDL_00094 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GHMDDCDL_00095 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GHMDDCDL_00096 4.1e-43 yrzL S Belongs to the UPF0297 family
GHMDDCDL_00097 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GHMDDCDL_00098 6.1e-48 yrzB S Belongs to the UPF0473 family
GHMDDCDL_00099 2.7e-86 cvpA S Colicin V production protein
GHMDDCDL_00100 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GHMDDCDL_00101 6.1e-54 trxA O Belongs to the thioredoxin family
GHMDDCDL_00107 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GHMDDCDL_00108 4.3e-275 lysP E amino acid
GHMDDCDL_00109 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
GHMDDCDL_00110 1.5e-118 lssY 3.6.1.27 I phosphatase
GHMDDCDL_00111 1e-81 S Threonine/Serine exporter, ThrE
GHMDDCDL_00112 2.6e-127 thrE S Putative threonine/serine exporter
GHMDDCDL_00113 1e-30 cspC K Cold shock protein
GHMDDCDL_00114 1.6e-123 sirR K iron dependent repressor
GHMDDCDL_00115 5.5e-164 czcD P cation diffusion facilitator family transporter
GHMDDCDL_00116 2.5e-116 S membrane
GHMDDCDL_00117 8.4e-109 S VIT family
GHMDDCDL_00118 2.7e-82 usp1 T Belongs to the universal stress protein A family
GHMDDCDL_00119 1.5e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHMDDCDL_00120 9.7e-152 glnH ET ABC transporter
GHMDDCDL_00121 2.4e-110 gluC P ABC transporter permease
GHMDDCDL_00122 3.6e-109 glnP P ABC transporter permease
GHMDDCDL_00123 8.3e-221 S CAAX protease self-immunity
GHMDDCDL_00124 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHMDDCDL_00125 5.1e-52
GHMDDCDL_00126 3.1e-72 merR K MerR HTH family regulatory protein
GHMDDCDL_00127 2.1e-269 lmrB EGP Major facilitator Superfamily
GHMDDCDL_00128 1.9e-122 S Domain of unknown function (DUF4811)
GHMDDCDL_00129 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GHMDDCDL_00131 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHMDDCDL_00132 3.8e-90 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GHMDDCDL_00133 1.7e-187 I Alpha beta
GHMDDCDL_00134 8.5e-271 emrY EGP Major facilitator Superfamily
GHMDDCDL_00135 4.7e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
GHMDDCDL_00136 9.4e-253 yjjP S Putative threonine/serine exporter
GHMDDCDL_00137 1.1e-158 mleR K LysR family
GHMDDCDL_00138 1.1e-112 ydjP I Alpha/beta hydrolase family
GHMDDCDL_00139 4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GHMDDCDL_00140 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
GHMDDCDL_00141 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
GHMDDCDL_00142 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
GHMDDCDL_00143 1.7e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GHMDDCDL_00144 6.1e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
GHMDDCDL_00145 1.4e-125 citR K sugar-binding domain protein
GHMDDCDL_00146 9.3e-203 P Sodium:sulfate symporter transmembrane region
GHMDDCDL_00147 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHMDDCDL_00148 4.5e-266 frdC 1.3.5.4 C FAD binding domain
GHMDDCDL_00149 1.2e-258 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GHMDDCDL_00150 3.6e-252 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GHMDDCDL_00151 6.4e-39 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GHMDDCDL_00152 4.3e-158 mleR K LysR family
GHMDDCDL_00153 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHMDDCDL_00154 3.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
GHMDDCDL_00155 3.9e-295 L PFAM plasmid pRiA4b ORF-3 family protein
GHMDDCDL_00156 1.1e-169 L transposase, IS605 OrfB family
GHMDDCDL_00157 2.1e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
GHMDDCDL_00158 8.3e-21
GHMDDCDL_00159 7.8e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GHMDDCDL_00160 3e-75
GHMDDCDL_00161 6.6e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GHMDDCDL_00162 5.9e-130 ponA V Beta-lactamase enzyme family
GHMDDCDL_00163 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
GHMDDCDL_00164 1.3e-216 uhpT EGP Major facilitator Superfamily
GHMDDCDL_00165 1.7e-259 ytjP 3.5.1.18 E Dipeptidase
GHMDDCDL_00166 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
GHMDDCDL_00167 3e-181 yfeX P Peroxidase
GHMDDCDL_00168 7.6e-91 lsa S ABC transporter
GHMDDCDL_00169 2.8e-158 lsa S ABC transporter
GHMDDCDL_00170 2.3e-133 I alpha/beta hydrolase fold
GHMDDCDL_00171 4e-179 MA20_14895 S Conserved hypothetical protein 698
GHMDDCDL_00172 1.2e-94 S NADPH-dependent FMN reductase
GHMDDCDL_00173 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GHMDDCDL_00174 2.6e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GHMDDCDL_00175 9.7e-231 mntH P H( )-stimulated, divalent metal cation uptake system
GHMDDCDL_00176 1.9e-79 Q Methyltransferase
GHMDDCDL_00177 9.1e-116 ktrA P domain protein
GHMDDCDL_00178 5.8e-239 ktrB P Potassium uptake protein
GHMDDCDL_00179 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
GHMDDCDL_00180 1.9e-121 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GHMDDCDL_00181 3.8e-223 G Glycosyl hydrolases family 8
GHMDDCDL_00182 9e-234 ydaM M Glycosyl transferase family group 2
GHMDDCDL_00184 6.2e-141
GHMDDCDL_00185 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
GHMDDCDL_00186 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHMDDCDL_00187 1.3e-154 pstA P Phosphate transport system permease protein PstA
GHMDDCDL_00188 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
GHMDDCDL_00189 4.6e-160 pstS P Phosphate
GHMDDCDL_00190 6e-134 K Transcriptional regulatory protein, C-terminal domain protein
GHMDDCDL_00191 6.7e-250 L Transposase
GHMDDCDL_00192 3.3e-17 K Transcriptional regulator, HxlR family
GHMDDCDL_00193 3.1e-184
GHMDDCDL_00194 1.2e-97 2.3.1.128 K acetyltransferase
GHMDDCDL_00195 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
GHMDDCDL_00196 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
GHMDDCDL_00197 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHMDDCDL_00198 3.9e-182
GHMDDCDL_00199 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHMDDCDL_00200 1.7e-183 S Phosphotransferase system, EIIC
GHMDDCDL_00201 8.6e-119 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GHMDDCDL_00202 9.3e-169 cvfB S S1 domain
GHMDDCDL_00203 6.6e-162 xerD D recombinase XerD
GHMDDCDL_00204 1.1e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GHMDDCDL_00205 5.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GHMDDCDL_00206 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GHMDDCDL_00207 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHMDDCDL_00208 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GHMDDCDL_00209 6.7e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
GHMDDCDL_00210 5.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
GHMDDCDL_00211 2.5e-13 M Lysin motif
GHMDDCDL_00212 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GHMDDCDL_00213 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
GHMDDCDL_00214 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GHMDDCDL_00215 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GHMDDCDL_00216 2.6e-233 S Tetratricopeptide repeat protein
GHMDDCDL_00217 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GHMDDCDL_00218 0.0 yfmR S ABC transporter, ATP-binding protein
GHMDDCDL_00219 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GHMDDCDL_00220 1.6e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GHMDDCDL_00221 2.9e-111 hlyIII S protein, hemolysin III
GHMDDCDL_00222 7.1e-150 DegV S EDD domain protein, DegV family
GHMDDCDL_00223 3.7e-168 ypmR E lipolytic protein G-D-S-L family
GHMDDCDL_00224 3.7e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GHMDDCDL_00225 4.4e-35 yozE S Belongs to the UPF0346 family
GHMDDCDL_00226 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GHMDDCDL_00227 2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHMDDCDL_00228 3.9e-159 dprA LU DNA protecting protein DprA
GHMDDCDL_00229 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHMDDCDL_00230 1.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
GHMDDCDL_00231 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHMDDCDL_00232 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHMDDCDL_00233 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHMDDCDL_00234 8.1e-79 F NUDIX domain
GHMDDCDL_00235 1.1e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
GHMDDCDL_00236 2.7e-67 yqkB S Belongs to the HesB IscA family
GHMDDCDL_00237 1e-48
GHMDDCDL_00239 1.2e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
GHMDDCDL_00240 3.7e-61 asp S Asp23 family, cell envelope-related function
GHMDDCDL_00241 6.1e-25
GHMDDCDL_00242 3.9e-93
GHMDDCDL_00243 1.4e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GHMDDCDL_00244 4.9e-182 K Transcriptional regulator, LacI family
GHMDDCDL_00245 1.2e-231 gntT EG Gluconate
GHMDDCDL_00246 8e-293 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GHMDDCDL_00247 2.9e-96 K Acetyltransferase (GNAT) domain
GHMDDCDL_00248 5.4e-47
GHMDDCDL_00249 2.4e-22
GHMDDCDL_00250 2.2e-44
GHMDDCDL_00251 4.6e-36 yhaI S Protein of unknown function (DUF805)
GHMDDCDL_00252 5.8e-106 L Uncharacterized conserved protein (DUF2075)
GHMDDCDL_00253 0.0 L PLD-like domain
GHMDDCDL_00255 5.1e-158 yjmB G MFS/sugar transport protein
GHMDDCDL_00256 9.2e-230 uxaC 5.3.1.12 G glucuronate isomerase
GHMDDCDL_00257 1.8e-98 S module of peptide synthetase
GHMDDCDL_00259 3.7e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GHMDDCDL_00260 2.8e-125 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GHMDDCDL_00261 2.5e-89 yqhA G Aldose 1-epimerase
GHMDDCDL_00262 3.1e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
GHMDDCDL_00263 3.1e-164 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GHMDDCDL_00264 1.7e-126 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
GHMDDCDL_00265 1.7e-53 kdgR K FCD domain
GHMDDCDL_00266 2.1e-211 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
GHMDDCDL_00267 2.6e-181 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GHMDDCDL_00268 1.1e-217 uxuT G MFS/sugar transport protein
GHMDDCDL_00269 3.9e-220 uxaC 5.3.1.12 G glucuronate isomerase
GHMDDCDL_00270 2.7e-13 higA K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00271 2e-13 higA K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00272 3.1e-47 G Xylose isomerase-like TIM barrel
GHMDDCDL_00273 6.3e-138 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GHMDDCDL_00274 2.7e-130 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GHMDDCDL_00275 7.2e-69 K Bacterial transcriptional regulator
GHMDDCDL_00276 2.2e-139 K LysR substrate binding domain protein
GHMDDCDL_00277 1.7e-68 C Flavodoxin
GHMDDCDL_00278 2.2e-75 yphH S Cupin domain
GHMDDCDL_00279 6.7e-70 yeaL S UPF0756 membrane protein
GHMDDCDL_00280 6.5e-233 EGP Major facilitator Superfamily
GHMDDCDL_00281 5.5e-74 copY K Copper transport repressor CopY TcrY
GHMDDCDL_00282 7.2e-245 yhdP S Transporter associated domain
GHMDDCDL_00283 0.0 ubiB S ABC1 family
GHMDDCDL_00284 3.3e-144 S DUF218 domain
GHMDDCDL_00285 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GHMDDCDL_00286 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHMDDCDL_00287 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHMDDCDL_00288 0.0 uvrA3 L excinuclease ABC, A subunit
GHMDDCDL_00289 5.7e-121 S SNARE associated Golgi protein
GHMDDCDL_00290 2.3e-229 N Uncharacterized conserved protein (DUF2075)
GHMDDCDL_00291 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GHMDDCDL_00293 6.6e-254 yifK E Amino acid permease
GHMDDCDL_00294 7.2e-158 endA V DNA/RNA non-specific endonuclease
GHMDDCDL_00295 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHMDDCDL_00296 2.3e-41 ybaN S Protein of unknown function (DUF454)
GHMDDCDL_00297 7e-72 S Protein of unknown function (DUF3290)
GHMDDCDL_00298 6.2e-114 yviA S Protein of unknown function (DUF421)
GHMDDCDL_00299 1.2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
GHMDDCDL_00300 2e-18
GHMDDCDL_00301 2.1e-90 ntd 2.4.2.6 F Nucleoside
GHMDDCDL_00302 3.3e-152 3.1.3.102, 3.1.3.104 S hydrolase
GHMDDCDL_00303 8.9e-41 yrvD S Pfam:DUF1049
GHMDDCDL_00306 1.2e-76 hit FG histidine triad
GHMDDCDL_00307 6.7e-136 ecsA V ABC transporter, ATP-binding protein
GHMDDCDL_00308 7.3e-217 ecsB U ABC transporter
GHMDDCDL_00309 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GHMDDCDL_00310 2.5e-16 S YSIRK type signal peptide
GHMDDCDL_00311 9.5e-16 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GHMDDCDL_00312 1.5e-13 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GHMDDCDL_00313 4.4e-65 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
GHMDDCDL_00314 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
GHMDDCDL_00315 1.1e-56 ytzB S Small secreted protein
GHMDDCDL_00316 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GHMDDCDL_00317 1.1e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHMDDCDL_00318 3.8e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GHMDDCDL_00319 1.4e-119 ybhL S Belongs to the BI1 family
GHMDDCDL_00320 2e-71 yoaK S Protein of unknown function (DUF1275)
GHMDDCDL_00321 1e-15 yoaK S Protein of unknown function (DUF1275)
GHMDDCDL_00322 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHMDDCDL_00323 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GHMDDCDL_00324 3.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GHMDDCDL_00325 1.9e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GHMDDCDL_00326 3e-222 dnaB L replication initiation and membrane attachment
GHMDDCDL_00327 1.9e-172 dnaI L Primosomal protein DnaI
GHMDDCDL_00328 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GHMDDCDL_00329 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GHMDDCDL_00330 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GHMDDCDL_00331 1.4e-95 yqeG S HAD phosphatase, family IIIA
GHMDDCDL_00332 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
GHMDDCDL_00333 1.9e-47 yhbY J RNA-binding protein
GHMDDCDL_00334 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GHMDDCDL_00335 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GHMDDCDL_00336 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GHMDDCDL_00337 1.1e-135 yqeM Q Methyltransferase
GHMDDCDL_00338 4.1e-209 ylbM S Belongs to the UPF0348 family
GHMDDCDL_00339 2.9e-99 yceD S Uncharacterized ACR, COG1399
GHMDDCDL_00340 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GHMDDCDL_00341 1.5e-121 K response regulator
GHMDDCDL_00342 3.7e-279 arlS 2.7.13.3 T Histidine kinase
GHMDDCDL_00343 1.3e-266 yjeM E Amino Acid
GHMDDCDL_00344 2.9e-235 V MatE
GHMDDCDL_00345 5.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GHMDDCDL_00346 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHMDDCDL_00347 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GHMDDCDL_00348 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHMDDCDL_00349 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHMDDCDL_00350 6.7e-59 yodB K Transcriptional regulator, HxlR family
GHMDDCDL_00351 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GHMDDCDL_00352 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHMDDCDL_00353 3.6e-114 rlpA M PFAM NLP P60 protein
GHMDDCDL_00354 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
GHMDDCDL_00355 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHMDDCDL_00356 4.1e-68 yneR S Belongs to the HesB IscA family
GHMDDCDL_00357 0.0 S membrane
GHMDDCDL_00358 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
GHMDDCDL_00359 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GHMDDCDL_00360 5.2e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GHMDDCDL_00361 9.3e-66 gluP 3.4.21.105 S Peptidase, S54 family
GHMDDCDL_00362 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
GHMDDCDL_00363 5.6e-183 glk 2.7.1.2 G Glucokinase
GHMDDCDL_00364 2.9e-66 yqhL P Rhodanese-like protein
GHMDDCDL_00365 0.0 lacS G Transporter
GHMDDCDL_00366 2.3e-28
GHMDDCDL_00367 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GHMDDCDL_00368 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GHMDDCDL_00369 4.4e-190 yeaN P Transporter, major facilitator family protein
GHMDDCDL_00370 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
GHMDDCDL_00371 2.7e-82 nrdI F Belongs to the NrdI family
GHMDDCDL_00372 1.6e-236 yhdP S Transporter associated domain
GHMDDCDL_00373 1.1e-153 ypdB V (ABC) transporter
GHMDDCDL_00374 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
GHMDDCDL_00375 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
GHMDDCDL_00376 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
GHMDDCDL_00377 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
GHMDDCDL_00378 1e-159 S AI-2E family transporter
GHMDDCDL_00379 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
GHMDDCDL_00380 7e-127
GHMDDCDL_00381 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GHMDDCDL_00382 4.1e-150 K helix_turn_helix, arabinose operon control protein
GHMDDCDL_00383 1.8e-100 pgm1 3.1.3.73 G phosphoglycerate mutase
GHMDDCDL_00384 3.1e-77 P Cadmium resistance transporter
GHMDDCDL_00385 2.3e-70 fld C Flavodoxin
GHMDDCDL_00386 1.1e-90 cobO 2.5.1.17 S Cobalamin adenosyltransferase
GHMDDCDL_00387 7e-174 cobD 4.1.1.81 E Aminotransferase class I and II
GHMDDCDL_00388 1.9e-221 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
GHMDDCDL_00389 1.8e-157 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GHMDDCDL_00390 2.1e-107 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
GHMDDCDL_00391 1.8e-191 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GHMDDCDL_00392 2.4e-91 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GHMDDCDL_00393 1.3e-83 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
GHMDDCDL_00394 4.6e-132 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GHMDDCDL_00395 4.1e-155 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
GHMDDCDL_00396 1.7e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GHMDDCDL_00397 2.5e-114 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
GHMDDCDL_00398 1e-198 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GHMDDCDL_00399 1e-118 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
GHMDDCDL_00400 2.6e-105 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
GHMDDCDL_00401 4.7e-129 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GHMDDCDL_00402 3.8e-48 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GHMDDCDL_00403 1e-106 cbiQ P Cobalt transport protein
GHMDDCDL_00404 3.9e-137 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
GHMDDCDL_00405 3.4e-256 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
GHMDDCDL_00406 1.7e-65 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
GHMDDCDL_00407 2.8e-206 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GHMDDCDL_00408 2.3e-146 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GHMDDCDL_00409 1.9e-175 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
GHMDDCDL_00410 3.4e-244 hemL 5.4.3.8 H Aminotransferase class-III
GHMDDCDL_00411 5.1e-86 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
GHMDDCDL_00412 1e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GHMDDCDL_00413 5.8e-82 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
GHMDDCDL_00414 7.4e-100 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GHMDDCDL_00415 6.5e-161 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
GHMDDCDL_00416 4.7e-69 S ECF transporter, substrate-specific component
GHMDDCDL_00417 3.5e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GHMDDCDL_00418 2.3e-166
GHMDDCDL_00419 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHMDDCDL_00420 9e-242 purD 6.3.4.13 F Belongs to the GARS family
GHMDDCDL_00421 4.6e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GHMDDCDL_00422 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GHMDDCDL_00423 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GHMDDCDL_00424 2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GHMDDCDL_00425 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHMDDCDL_00426 1.4e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHMDDCDL_00427 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHMDDCDL_00428 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GHMDDCDL_00429 8.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GHMDDCDL_00430 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GHMDDCDL_00431 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GHMDDCDL_00432 1.4e-100 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHMDDCDL_00433 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GHMDDCDL_00434 5.4e-185 thrC 4.2.3.1 E Threonine synthase
GHMDDCDL_00435 1.6e-21 K helix_turn_helix, arabinose operon control protein
GHMDDCDL_00436 2.9e-19 mocA S Oxidoreductase
GHMDDCDL_00437 1.7e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GHMDDCDL_00438 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GHMDDCDL_00439 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GHMDDCDL_00440 1.5e-173 K AI-2E family transporter
GHMDDCDL_00441 1.5e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GHMDDCDL_00442 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GHMDDCDL_00443 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
GHMDDCDL_00444 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHMDDCDL_00445 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GHMDDCDL_00446 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GHMDDCDL_00447 5.2e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHMDDCDL_00448 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GHMDDCDL_00449 2.9e-124 K LysR substrate binding domain
GHMDDCDL_00450 1.6e-52 azlD S branched-chain amino acid
GHMDDCDL_00451 2.3e-138 azlC E AzlC protein
GHMDDCDL_00452 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
GHMDDCDL_00453 3.8e-125 K response regulator
GHMDDCDL_00454 9.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GHMDDCDL_00455 1.2e-169 deoR K sugar-binding domain protein
GHMDDCDL_00456 4e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GHMDDCDL_00457 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
GHMDDCDL_00458 2.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GHMDDCDL_00459 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHMDDCDL_00460 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHMDDCDL_00461 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GHMDDCDL_00462 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GHMDDCDL_00463 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
GHMDDCDL_00464 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHMDDCDL_00465 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GHMDDCDL_00466 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GHMDDCDL_00467 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GHMDDCDL_00468 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
GHMDDCDL_00469 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHMDDCDL_00470 7.1e-49 yazA L GIY-YIG catalytic domain protein
GHMDDCDL_00471 2.7e-140 yabB 2.1.1.223 L Methyltransferase small domain
GHMDDCDL_00472 4.6e-117 plsC 2.3.1.51 I Acyltransferase
GHMDDCDL_00473 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
GHMDDCDL_00474 1.3e-35 ynzC S UPF0291 protein
GHMDDCDL_00475 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHMDDCDL_00476 2.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GHMDDCDL_00477 2.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHMDDCDL_00479 5.1e-10
GHMDDCDL_00485 8.8e-106 S D5 N terminal like
GHMDDCDL_00488 4.6e-07
GHMDDCDL_00491 1.8e-41 S Phage regulatory protein Rha (Phage_pRha)
GHMDDCDL_00492 1.6e-14 S Helix-turn-helix domain
GHMDDCDL_00493 3.9e-10 K sequence-specific DNA binding
GHMDDCDL_00494 1.8e-34 S Domain of unknown function (DUF5067)
GHMDDCDL_00495 2.7e-133 L Belongs to the 'phage' integrase family
GHMDDCDL_00496 7.3e-88
GHMDDCDL_00497 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GHMDDCDL_00498 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GHMDDCDL_00499 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GHMDDCDL_00500 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GHMDDCDL_00501 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GHMDDCDL_00502 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHMDDCDL_00503 1.1e-07
GHMDDCDL_00504 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
GHMDDCDL_00505 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
GHMDDCDL_00506 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GHMDDCDL_00507 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHMDDCDL_00508 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GHMDDCDL_00509 7.8e-163 S Tetratricopeptide repeat
GHMDDCDL_00510 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHMDDCDL_00511 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GHMDDCDL_00512 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
GHMDDCDL_00513 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
GHMDDCDL_00514 0.0 comEC S Competence protein ComEC
GHMDDCDL_00515 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
GHMDDCDL_00516 5.8e-80 comEA L Competence protein ComEA
GHMDDCDL_00517 1.9e-197 ylbL T Belongs to the peptidase S16 family
GHMDDCDL_00518 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GHMDDCDL_00519 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GHMDDCDL_00520 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GHMDDCDL_00521 2.7e-222 ftsW D Belongs to the SEDS family
GHMDDCDL_00522 0.0 typA T GTP-binding protein TypA
GHMDDCDL_00523 1.3e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GHMDDCDL_00524 1.9e-46 yktA S Belongs to the UPF0223 family
GHMDDCDL_00525 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
GHMDDCDL_00526 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GHMDDCDL_00527 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GHMDDCDL_00528 1.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GHMDDCDL_00529 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHMDDCDL_00530 2.7e-77
GHMDDCDL_00531 9.8e-32 ykzG S Belongs to the UPF0356 family
GHMDDCDL_00532 4.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
GHMDDCDL_00533 1.3e-28
GHMDDCDL_00534 3.8e-130 mltD CBM50 M NlpC P60 family protein
GHMDDCDL_00536 2.2e-57
GHMDDCDL_00537 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GHMDDCDL_00538 1e-216 EG GntP family permease
GHMDDCDL_00539 8.5e-84 KT Putative sugar diacid recognition
GHMDDCDL_00540 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHMDDCDL_00541 7.7e-219 patA 2.6.1.1 E Aminotransferase
GHMDDCDL_00542 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHMDDCDL_00543 1e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHMDDCDL_00544 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GHMDDCDL_00545 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GHMDDCDL_00546 6.9e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GHMDDCDL_00547 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
GHMDDCDL_00548 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GHMDDCDL_00549 2.6e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHMDDCDL_00550 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GHMDDCDL_00551 4.9e-117 S Repeat protein
GHMDDCDL_00552 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
GHMDDCDL_00553 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GHMDDCDL_00554 7.5e-58 XK27_04120 S Putative amino acid metabolism
GHMDDCDL_00555 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
GHMDDCDL_00556 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GHMDDCDL_00558 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GHMDDCDL_00559 4.2e-32 cspA K Cold shock protein
GHMDDCDL_00560 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GHMDDCDL_00561 1.6e-36 divIVA D DivIVA domain protein
GHMDDCDL_00562 6.4e-145 ylmH S S4 domain protein
GHMDDCDL_00563 1.1e-40 yggT S YGGT family
GHMDDCDL_00564 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GHMDDCDL_00565 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHMDDCDL_00566 7.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GHMDDCDL_00567 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GHMDDCDL_00568 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GHMDDCDL_00569 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GHMDDCDL_00570 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHMDDCDL_00571 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GHMDDCDL_00572 1.3e-55 ftsL D Cell division protein FtsL
GHMDDCDL_00573 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GHMDDCDL_00574 3.1e-77 mraZ K Belongs to the MraZ family
GHMDDCDL_00575 1.9e-56
GHMDDCDL_00576 1.2e-10 S Protein of unknown function (DUF4044)
GHMDDCDL_00577 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GHMDDCDL_00578 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GHMDDCDL_00579 5.2e-156 rrmA 2.1.1.187 H Methyltransferase
GHMDDCDL_00580 9.5e-181 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GHMDDCDL_00581 1.3e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
GHMDDCDL_00582 2.8e-149 V Type I restriction-modification system methyltransferase subunit()
GHMDDCDL_00585 9.8e-18 D nuclear chromosome segregation
GHMDDCDL_00590 6.2e-71
GHMDDCDL_00591 2.6e-08 3.2.1.80, 3.4.24.40 L Protein of unknown function (DUF3991)
GHMDDCDL_00592 7.2e-11 T PFAM SpoVT AbrB
GHMDDCDL_00593 4.6e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GHMDDCDL_00595 5.9e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GHMDDCDL_00599 1.1e-68 ruvB 3.6.4.12 L four-way junction helicase activity
GHMDDCDL_00607 2.9e-12
GHMDDCDL_00619 9.4e-22 L Psort location Cytoplasmic, score
GHMDDCDL_00623 4.1e-10 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00625 5.8e-12 S protein disulfide oxidoreductase activity
GHMDDCDL_00626 2.1e-10 E Zn peptidase
GHMDDCDL_00627 6e-78 L Belongs to the 'phage' integrase family
GHMDDCDL_00629 7.2e-25 S FRG
GHMDDCDL_00631 3.9e-12
GHMDDCDL_00632 6.1e-42 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GHMDDCDL_00633 1e-31 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GHMDDCDL_00634 3.3e-95 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GHMDDCDL_00635 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GHMDDCDL_00636 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
GHMDDCDL_00637 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GHMDDCDL_00638 5.9e-22 S Protein of unknown function (DUF3042)
GHMDDCDL_00639 2.9e-48
GHMDDCDL_00640 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GHMDDCDL_00641 2.4e-56 K transcriptional regulator PadR family
GHMDDCDL_00642 8.7e-81 XK27_06920 S Protein of unknown function (DUF1700)
GHMDDCDL_00643 1.9e-133 S Putative adhesin
GHMDDCDL_00644 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GHMDDCDL_00645 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHMDDCDL_00646 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHMDDCDL_00647 3.4e-35 nrdH O Glutaredoxin
GHMDDCDL_00648 1.8e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GHMDDCDL_00649 1.2e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHMDDCDL_00650 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GHMDDCDL_00651 1.8e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GHMDDCDL_00652 2.8e-38 S Protein of unknown function (DUF2508)
GHMDDCDL_00653 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHMDDCDL_00654 2.9e-51 yaaQ S Cyclic-di-AMP receptor
GHMDDCDL_00655 3.2e-181 holB 2.7.7.7 L DNA polymerase III
GHMDDCDL_00656 3.1e-43 yabA L Involved in initiation control of chromosome replication
GHMDDCDL_00657 8.3e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHMDDCDL_00658 3.4e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
GHMDDCDL_00659 4.5e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GHMDDCDL_00660 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GHMDDCDL_00661 1.2e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GHMDDCDL_00662 5.7e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GHMDDCDL_00663 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GHMDDCDL_00664 8.9e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GHMDDCDL_00665 1.4e-192 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GHMDDCDL_00666 6.8e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GHMDDCDL_00667 7.6e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GHMDDCDL_00668 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GHMDDCDL_00669 1.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GHMDDCDL_00670 1.9e-225 mtnE 2.6.1.83 E Aminotransferase
GHMDDCDL_00671 2e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GHMDDCDL_00672 0.0 uup S ABC transporter, ATP-binding protein
GHMDDCDL_00673 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GHMDDCDL_00675 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GHMDDCDL_00676 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GHMDDCDL_00677 5.3e-81 S Aminoacyl-tRNA editing domain
GHMDDCDL_00678 4.5e-302 ybeC E amino acid
GHMDDCDL_00679 0.0 ydaO E amino acid
GHMDDCDL_00680 2.7e-39
GHMDDCDL_00681 2.4e-209 L Belongs to the 'phage' integrase family
GHMDDCDL_00682 5.7e-50 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GHMDDCDL_00683 1.7e-260 yfnA E amino acid
GHMDDCDL_00684 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GHMDDCDL_00685 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GHMDDCDL_00686 5.4e-40 ylqC S Belongs to the UPF0109 family
GHMDDCDL_00687 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GHMDDCDL_00688 2.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHMDDCDL_00689 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GHMDDCDL_00690 9.4e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHMDDCDL_00691 0.0 smc D Required for chromosome condensation and partitioning
GHMDDCDL_00692 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHMDDCDL_00693 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHMDDCDL_00694 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GHMDDCDL_00695 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHMDDCDL_00696 0.0 yloV S DAK2 domain fusion protein YloV
GHMDDCDL_00697 4.7e-58 asp S Asp23 family, cell envelope-related function
GHMDDCDL_00698 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GHMDDCDL_00699 9.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
GHMDDCDL_00700 4.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GHMDDCDL_00701 3.2e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GHMDDCDL_00702 0.0 KLT serine threonine protein kinase
GHMDDCDL_00703 2.1e-129 stp 3.1.3.16 T phosphatase
GHMDDCDL_00704 3.1e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GHMDDCDL_00705 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GHMDDCDL_00706 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHMDDCDL_00707 9.6e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GHMDDCDL_00708 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GHMDDCDL_00709 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GHMDDCDL_00710 4.2e-53
GHMDDCDL_00711 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
GHMDDCDL_00712 1.8e-75 argR K Regulates arginine biosynthesis genes
GHMDDCDL_00713 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GHMDDCDL_00714 6.4e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GHMDDCDL_00715 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHMDDCDL_00716 3.4e-215 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHMDDCDL_00717 8.8e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHMDDCDL_00718 6.8e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GHMDDCDL_00719 2.2e-70 yqhY S Asp23 family, cell envelope-related function
GHMDDCDL_00720 1.7e-114 J 2'-5' RNA ligase superfamily
GHMDDCDL_00721 9.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GHMDDCDL_00722 9.9e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GHMDDCDL_00723 1.3e-67 K FR47-like protein
GHMDDCDL_00724 8.4e-45 L Transposase DDE domain
GHMDDCDL_00725 9.2e-09 2.7.13.3 T GHKL domain
GHMDDCDL_00727 1.4e-259 S Putative peptidoglycan binding domain
GHMDDCDL_00728 3.3e-22
GHMDDCDL_00729 7.8e-214 bacI V MacB-like periplasmic core domain
GHMDDCDL_00730 2.8e-128 V ABC transporter
GHMDDCDL_00731 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GHMDDCDL_00732 9.8e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GHMDDCDL_00733 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GHMDDCDL_00734 1.9e-149 E Glyoxalase-like domain
GHMDDCDL_00735 7.5e-155 glcU U sugar transport
GHMDDCDL_00736 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
GHMDDCDL_00737 3.5e-94 S reductase
GHMDDCDL_00739 8.8e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHMDDCDL_00740 7.5e-175 ABC-SBP S ABC transporter
GHMDDCDL_00741 4.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
GHMDDCDL_00742 4.7e-214 htrA 3.4.21.107 O serine protease
GHMDDCDL_00743 2.3e-153 vicX 3.1.26.11 S domain protein
GHMDDCDL_00744 7.8e-149 yycI S YycH protein
GHMDDCDL_00745 6.9e-245 yycH S YycH protein
GHMDDCDL_00746 0.0 vicK 2.7.13.3 T Histidine kinase
GHMDDCDL_00747 3.1e-130 K response regulator
GHMDDCDL_00749 4.4e-308 lmrA 3.6.3.44 V ABC transporter
GHMDDCDL_00750 1.4e-72 K helix_turn_helix multiple antibiotic resistance protein
GHMDDCDL_00752 1.5e-122 Z012_01130 S Fic/DOC family
GHMDDCDL_00753 9.6e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
GHMDDCDL_00754 3.6e-50
GHMDDCDL_00755 9e-207 yttB EGP Major facilitator Superfamily
GHMDDCDL_00756 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GHMDDCDL_00757 2e-74 rplI J Binds to the 23S rRNA
GHMDDCDL_00758 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GHMDDCDL_00759 2.6e-100 deoR K sugar-binding domain protein
GHMDDCDL_00760 1.2e-46 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHMDDCDL_00761 1.6e-30 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHMDDCDL_00762 1.2e-118 ybhL S Belongs to the BI1 family
GHMDDCDL_00763 4.2e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
GHMDDCDL_00764 6.7e-195 S Protein of unknown function (DUF3114)
GHMDDCDL_00765 1.2e-296 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GHMDDCDL_00766 1.1e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GHMDDCDL_00767 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
GHMDDCDL_00768 9.1e-62 S Domain of unknown function (DUF4828)
GHMDDCDL_00769 5.9e-191 mocA S Oxidoreductase
GHMDDCDL_00770 7.4e-231 yfmL L DEAD DEAH box helicase
GHMDDCDL_00772 9.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHMDDCDL_00773 6.7e-54
GHMDDCDL_00774 2.3e-67 gtcA S Teichoic acid glycosylation protein
GHMDDCDL_00775 1.8e-78 fld C Flavodoxin
GHMDDCDL_00776 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
GHMDDCDL_00777 2.7e-221 arcT 2.6.1.1 E Aminotransferase
GHMDDCDL_00778 1.4e-254 E Arginine ornithine antiporter
GHMDDCDL_00779 1.5e-280 yjeM E Amino Acid
GHMDDCDL_00780 1.5e-142 yihY S Belongs to the UPF0761 family
GHMDDCDL_00781 6.6e-34 S Protein of unknown function (DUF2922)
GHMDDCDL_00782 4.9e-31
GHMDDCDL_00783 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
GHMDDCDL_00784 1.3e-147 cps1D M Domain of unknown function (DUF4422)
GHMDDCDL_00785 1.6e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GHMDDCDL_00786 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
GHMDDCDL_00787 2.7e-73 cps3F
GHMDDCDL_00788 3.6e-92 M transferase activity, transferring glycosyl groups
GHMDDCDL_00789 2.3e-28 M biosynthesis protein
GHMDDCDL_00790 2e-64 M Domain of unknown function (DUF4422)
GHMDDCDL_00791 6.2e-80 M Core-2/I-Branching enzyme
GHMDDCDL_00792 1.9e-151 ykoT GT2 M Glycosyl transferase family 2
GHMDDCDL_00793 9.8e-72 S Acyltransferase family
GHMDDCDL_00794 1.1e-31
GHMDDCDL_00795 1.3e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
GHMDDCDL_00796 8.9e-230 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
GHMDDCDL_00797 4.3e-75 waaB GT4 M Glycosyl transferases group 1
GHMDDCDL_00798 1.4e-62 cps3I G Acyltransferase family
GHMDDCDL_00799 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
GHMDDCDL_00800 2.6e-43 ltrA S Bacterial low temperature requirement A protein (LtrA)
GHMDDCDL_00801 1.6e-79 uspA T universal stress protein
GHMDDCDL_00802 4e-78 K AsnC family
GHMDDCDL_00803 4.5e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GHMDDCDL_00804 2.4e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
GHMDDCDL_00805 5.4e-181 galR K Transcriptional regulator
GHMDDCDL_00806 4e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GHMDDCDL_00807 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GHMDDCDL_00808 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
GHMDDCDL_00809 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
GHMDDCDL_00810 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
GHMDDCDL_00811 9.1e-36
GHMDDCDL_00812 2e-52
GHMDDCDL_00813 5.3e-201
GHMDDCDL_00814 1.2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHMDDCDL_00815 2.9e-134 pnuC H nicotinamide mononucleotide transporter
GHMDDCDL_00816 1.1e-155 ytbE 1.1.1.346 S Aldo keto reductase
GHMDDCDL_00817 1.2e-123 K response regulator
GHMDDCDL_00818 9e-181 T PhoQ Sensor
GHMDDCDL_00819 9.4e-130 macB2 V ABC transporter, ATP-binding protein
GHMDDCDL_00820 0.0 ysaB V FtsX-like permease family
GHMDDCDL_00821 4.5e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GHMDDCDL_00822 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GHMDDCDL_00823 6.2e-10 K helix_turn_helix, mercury resistance
GHMDDCDL_00824 8.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHMDDCDL_00825 2e-195 EGP Major facilitator Superfamily
GHMDDCDL_00826 6e-88 ymdB S Macro domain protein
GHMDDCDL_00827 1.4e-105 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00828 0.0 pepO 3.4.24.71 O Peptidase family M13
GHMDDCDL_00829 1.4e-47
GHMDDCDL_00830 6e-233 S Putative metallopeptidase domain
GHMDDCDL_00831 4.4e-203 3.1.3.1 S associated with various cellular activities
GHMDDCDL_00832 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GHMDDCDL_00833 5.9e-64 yeaO S Protein of unknown function, DUF488
GHMDDCDL_00835 1.5e-118 yrkL S Flavodoxin-like fold
GHMDDCDL_00836 1.5e-52
GHMDDCDL_00837 1.8e-16 S Domain of unknown function (DUF4767)
GHMDDCDL_00838 4.4e-177 L PFAM transposase, IS4 family protein
GHMDDCDL_00839 2.3e-30 2.1.1.72 D peptidase
GHMDDCDL_00840 1.7e-47
GHMDDCDL_00841 2.6e-205 nrnB S DHHA1 domain
GHMDDCDL_00842 5.2e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
GHMDDCDL_00843 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
GHMDDCDL_00844 1.1e-104 NU mannosyl-glycoprotein
GHMDDCDL_00845 1.9e-72 S Putative ABC-transporter type IV
GHMDDCDL_00846 4.7e-61 S Putative ABC-transporter type IV
GHMDDCDL_00847 1.9e-273 S ABC transporter, ATP-binding protein
GHMDDCDL_00848 6.4e-18 K Helix-turn-helix domain
GHMDDCDL_00851 4.6e-48 L Integrase
GHMDDCDL_00852 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHMDDCDL_00853 2e-274 pipD E Dipeptidase
GHMDDCDL_00854 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
GHMDDCDL_00856 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHMDDCDL_00857 7.5e-58
GHMDDCDL_00858 1.2e-177 prmA J Ribosomal protein L11 methyltransferase
GHMDDCDL_00859 6.7e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GHMDDCDL_00860 9.4e-50
GHMDDCDL_00861 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHMDDCDL_00862 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GHMDDCDL_00863 9.3e-166 yniA G Phosphotransferase enzyme family
GHMDDCDL_00864 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GHMDDCDL_00865 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHMDDCDL_00866 7.2e-262 glnPH2 P ABC transporter permease
GHMDDCDL_00867 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GHMDDCDL_00868 3.8e-70 yqeY S YqeY-like protein
GHMDDCDL_00869 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHMDDCDL_00870 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GHMDDCDL_00871 3.5e-263 argH 4.3.2.1 E argininosuccinate lyase
GHMDDCDL_00872 1.3e-83 bioY S BioY family
GHMDDCDL_00873 2.2e-171 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GHMDDCDL_00874 4.5e-183 phoH T phosphate starvation-inducible protein PhoH
GHMDDCDL_00875 1.2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHMDDCDL_00876 5.1e-58 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GHMDDCDL_00877 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GHMDDCDL_00878 2.9e-145 recO L Involved in DNA repair and RecF pathway recombination
GHMDDCDL_00879 2.9e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GHMDDCDL_00880 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GHMDDCDL_00881 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHMDDCDL_00882 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHMDDCDL_00883 2.1e-106 yvyE 3.4.13.9 S YigZ family
GHMDDCDL_00884 5.2e-248 comFA L Helicase C-terminal domain protein
GHMDDCDL_00885 3.9e-114 comFC S Competence protein
GHMDDCDL_00886 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHMDDCDL_00887 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHMDDCDL_00888 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHMDDCDL_00889 7.7e-31 KT PspC domain protein
GHMDDCDL_00890 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GHMDDCDL_00891 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GHMDDCDL_00892 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GHMDDCDL_00893 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GHMDDCDL_00894 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GHMDDCDL_00895 1.7e-136 yrjD S LUD domain
GHMDDCDL_00896 1.3e-292 lutB C 4Fe-4S dicluster domain
GHMDDCDL_00897 7.8e-168 lutA C Cysteine-rich domain
GHMDDCDL_00898 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHMDDCDL_00899 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GHMDDCDL_00900 2.9e-162 aatB ET PFAM extracellular solute-binding protein, family 3
GHMDDCDL_00901 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
GHMDDCDL_00902 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GHMDDCDL_00903 5.1e-116 yfbR S HD containing hydrolase-like enzyme
GHMDDCDL_00904 6.9e-14
GHMDDCDL_00905 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GHMDDCDL_00906 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHMDDCDL_00907 3.2e-245 steT E amino acid
GHMDDCDL_00908 4.9e-162 rapZ S Displays ATPase and GTPase activities
GHMDDCDL_00909 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GHMDDCDL_00910 1.5e-169 whiA K May be required for sporulation
GHMDDCDL_00912 8.8e-15
GHMDDCDL_00913 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHMDDCDL_00915 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GHMDDCDL_00916 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GHMDDCDL_00917 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHMDDCDL_00918 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHMDDCDL_00919 1.2e-244 yifK E Amino acid permease
GHMDDCDL_00920 2.4e-289 clcA P chloride
GHMDDCDL_00921 1.8e-34 secG U Preprotein translocase
GHMDDCDL_00922 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
GHMDDCDL_00923 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GHMDDCDL_00924 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GHMDDCDL_00925 9.1e-104 yxjI
GHMDDCDL_00926 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GHMDDCDL_00927 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GHMDDCDL_00928 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GHMDDCDL_00929 1.1e-86 K Acetyltransferase (GNAT) domain
GHMDDCDL_00930 2.6e-76 S PAS domain
GHMDDCDL_00931 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
GHMDDCDL_00932 1e-167 murB 1.3.1.98 M Cell wall formation
GHMDDCDL_00933 2.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHMDDCDL_00934 1.1e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GHMDDCDL_00935 2.6e-247 fucP G Major Facilitator Superfamily
GHMDDCDL_00936 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GHMDDCDL_00937 2.9e-125 ybbR S YbbR-like protein
GHMDDCDL_00938 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHMDDCDL_00939 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHMDDCDL_00940 5.6e-52
GHMDDCDL_00941 0.0 oatA I Acyltransferase
GHMDDCDL_00942 1.8e-78 K Transcriptional regulator
GHMDDCDL_00943 1.6e-146 XK27_02985 S Cof-like hydrolase
GHMDDCDL_00944 1.3e-76 lytE M Lysin motif
GHMDDCDL_00945 3.8e-24
GHMDDCDL_00946 1.4e-15 S Phage gp6-like head-tail connector protein
GHMDDCDL_00947 1.4e-180 S Caudovirus prohead serine protease
GHMDDCDL_00948 7.6e-139 S Phage portal protein
GHMDDCDL_00949 7.5e-199 terL S overlaps another CDS with the same product name
GHMDDCDL_00950 1.9e-25 terS L Phage terminase, small subunit
GHMDDCDL_00951 4.5e-31 L HNH endonuclease
GHMDDCDL_00952 1.5e-16 S Phage head-tail joining protein
GHMDDCDL_00954 8.4e-95 S Phage plasmid primase, P4
GHMDDCDL_00955 7.9e-45 L Bifunctional DNA primase/polymerase, N-terminal
GHMDDCDL_00959 4.8e-07 S Helix-turn-helix domain
GHMDDCDL_00960 1.3e-06 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_00961 2.5e-54 sip L Belongs to the 'phage' integrase family
GHMDDCDL_00962 1.2e-134 K response regulator
GHMDDCDL_00963 2.6e-272 yclK 2.7.13.3 T Histidine kinase
GHMDDCDL_00964 4.1e-153 glcU U sugar transport
GHMDDCDL_00965 2.4e-99 lacA 2.3.1.79 S Transferase hexapeptide repeat
GHMDDCDL_00966 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
GHMDDCDL_00967 1e-25
GHMDDCDL_00970 6.2e-31 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GHMDDCDL_00971 1.2e-154 KT YcbB domain
GHMDDCDL_00972 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GHMDDCDL_00973 1.1e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
GHMDDCDL_00974 3.9e-162 EG EamA-like transporter family
GHMDDCDL_00975 1.3e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GHMDDCDL_00976 6.2e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GHMDDCDL_00977 0.0 copA 3.6.3.54 P P-type ATPase
GHMDDCDL_00978 1.2e-85
GHMDDCDL_00980 2.3e-56
GHMDDCDL_00981 3.9e-40 yjcE P Sodium proton antiporter
GHMDDCDL_00982 5.5e-115 yjcE P Sodium proton antiporter
GHMDDCDL_00983 2.4e-47 yjcE P Sodium proton antiporter
GHMDDCDL_00987 2.5e-07
GHMDDCDL_00988 1.3e-37
GHMDDCDL_00994 3.4e-64 K Domain of unknown function (DUF4417)
GHMDDCDL_00996 4.3e-118 xtmA L Terminase small subunit
GHMDDCDL_00997 3.8e-219 S Terminase-like family
GHMDDCDL_00998 7.7e-216 S Phage portal protein, SPP1 Gp6-like
GHMDDCDL_00999 6.9e-150 S Phage Mu protein F like protein
GHMDDCDL_01000 2e-51 S Domain of unknown function (DUF4355)
GHMDDCDL_01001 4.6e-53
GHMDDCDL_01002 7.9e-167 S Phage major capsid protein E
GHMDDCDL_01003 3.6e-35
GHMDDCDL_01004 3.2e-59
GHMDDCDL_01005 3.6e-78
GHMDDCDL_01006 3.6e-50
GHMDDCDL_01007 2.9e-71 S Phage tail tube protein, TTP
GHMDDCDL_01008 9e-58
GHMDDCDL_01009 4e-33
GHMDDCDL_01010 0.0 M Phage tail tape measure protein TP901
GHMDDCDL_01011 8.4e-52
GHMDDCDL_01012 0.0 GT2,GT4 LM gp58-like protein
GHMDDCDL_01014 4.8e-12
GHMDDCDL_01015 3.6e-18 S Bacteriophage holin family
GHMDDCDL_01016 7.7e-185 M lysozyme activity
GHMDDCDL_01017 4.7e-10 T PFAM SpoVT AbrB
GHMDDCDL_01018 7.8e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GHMDDCDL_01019 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GHMDDCDL_01020 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GHMDDCDL_01021 1.1e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHMDDCDL_01022 2.2e-154 M Glycosyl transferase family group 2
GHMDDCDL_01023 1.1e-32 M Glycosyl transferase family group 2
GHMDDCDL_01024 2.8e-224 aadAT EK Aminotransferase, class I
GHMDDCDL_01025 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GHMDDCDL_01026 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GHMDDCDL_01027 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
GHMDDCDL_01028 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GHMDDCDL_01029 1.8e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHMDDCDL_01030 6.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GHMDDCDL_01031 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHMDDCDL_01032 1.1e-204 yacL S domain protein
GHMDDCDL_01033 1.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHMDDCDL_01034 4.7e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GHMDDCDL_01035 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
GHMDDCDL_01036 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GHMDDCDL_01037 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
GHMDDCDL_01038 1.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GHMDDCDL_01039 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHMDDCDL_01040 9.2e-119 tcyB E ABC transporter
GHMDDCDL_01041 1.5e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GHMDDCDL_01042 1.3e-167 I alpha/beta hydrolase fold
GHMDDCDL_01043 3e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHMDDCDL_01044 0.0 S Bacterial membrane protein, YfhO
GHMDDCDL_01045 2.2e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
GHMDDCDL_01046 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
GHMDDCDL_01048 0.0 yhgF K Tex-like protein N-terminal domain protein
GHMDDCDL_01049 2.2e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GHMDDCDL_01050 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHMDDCDL_01051 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
GHMDDCDL_01052 2.4e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GHMDDCDL_01053 1.1e-300 aspT P Predicted Permease Membrane Region
GHMDDCDL_01054 6.5e-249 EGP Major facilitator Superfamily
GHMDDCDL_01055 9.4e-110
GHMDDCDL_01058 1.1e-147 yjjH S Calcineurin-like phosphoesterase
GHMDDCDL_01059 1.7e-263 dtpT U amino acid peptide transporter
GHMDDCDL_01063 1e-14 K Cro/C1-type HTH DNA-binding domain
GHMDDCDL_01067 2.5e-84
GHMDDCDL_01068 1.3e-168 L Belongs to the 'phage' integrase family
GHMDDCDL_01069 3.1e-19 S Excisionase from transposon Tn916
GHMDDCDL_01072 4.3e-133
GHMDDCDL_01073 1.1e-12 S Helix-turn-helix domain
GHMDDCDL_01074 3e-19
GHMDDCDL_01076 2.5e-77 L Resolvase, N terminal domain
GHMDDCDL_01077 1.9e-09 L Resolvase, N terminal domain
GHMDDCDL_01078 2.6e-11 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GHMDDCDL_01081 1.2e-50 ebh D nuclear chromosome segregation
GHMDDCDL_01082 9e-17 K Cro/C1-type HTH DNA-binding domain
GHMDDCDL_01083 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GHMDDCDL_01084 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHMDDCDL_01085 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GHMDDCDL_01086 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHMDDCDL_01087 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHMDDCDL_01088 4.8e-252 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GHMDDCDL_01089 9.8e-67 yabR J RNA binding
GHMDDCDL_01090 5.6e-56 divIC D Septum formation initiator
GHMDDCDL_01091 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GHMDDCDL_01092 1.3e-221 norA EGP Major facilitator Superfamily
GHMDDCDL_01093 8.9e-41 1.3.5.4 S FMN binding
GHMDDCDL_01094 2.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHMDDCDL_01095 6.4e-263 yfnA E amino acid
GHMDDCDL_01096 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GHMDDCDL_01098 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GHMDDCDL_01099 0.0 helD 3.6.4.12 L DNA helicase
GHMDDCDL_01100 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
GHMDDCDL_01101 4e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
GHMDDCDL_01102 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHMDDCDL_01103 1e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GHMDDCDL_01104 2.2e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GHMDDCDL_01105 1.9e-175
GHMDDCDL_01106 1.2e-129 cobB K SIR2 family
GHMDDCDL_01108 1.2e-160 yunF F Protein of unknown function DUF72
GHMDDCDL_01109 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHMDDCDL_01110 1.5e-152 tatD L hydrolase, TatD family
GHMDDCDL_01111 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GHMDDCDL_01112 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GHMDDCDL_01113 6.8e-37 veg S Biofilm formation stimulator VEG
GHMDDCDL_01114 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GHMDDCDL_01115 3.1e-98 ydeN S Serine hydrolase
GHMDDCDL_01116 2.9e-27 psiE S Phosphate-starvation-inducible E
GHMDDCDL_01117 1.6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHMDDCDL_01119 1.2e-177 S Aldo keto reductase
GHMDDCDL_01120 1.7e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
GHMDDCDL_01121 0.0 L Helicase C-terminal domain protein
GHMDDCDL_01123 8.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GHMDDCDL_01124 2.6e-52 S Sugar efflux transporter for intercellular exchange
GHMDDCDL_01125 3e-125
GHMDDCDL_01126 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GHMDDCDL_01127 0.0 cadA P P-type ATPase
GHMDDCDL_01128 4.1e-220 5.4.2.7 G Metalloenzyme superfamily
GHMDDCDL_01130 3.6e-35 1.6.5.2 GM NAD(P)H-binding
GHMDDCDL_01131 4.2e-51 1.6.5.2 GM NAD(P)H-binding
GHMDDCDL_01132 3.4e-74 K Transcriptional regulator
GHMDDCDL_01133 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
GHMDDCDL_01134 2.4e-108 proWZ P ABC transporter permease
GHMDDCDL_01135 6.5e-142 proV E ABC transporter, ATP-binding protein
GHMDDCDL_01136 1.9e-102 proW P ABC transporter, permease protein
GHMDDCDL_01137 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GHMDDCDL_01138 2.6e-31 clcA P chloride
GHMDDCDL_01139 8.8e-54 clcA P chloride
GHMDDCDL_01140 6.1e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GHMDDCDL_01141 3.1e-103 metI P ABC transporter permease
GHMDDCDL_01142 5.2e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHMDDCDL_01143 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
GHMDDCDL_01144 9.2e-49 2.3.1.183 M Acetyltransferase GNAT family
GHMDDCDL_01145 9.5e-14 2.3.1.183 M Acetyltransferase GNAT family
GHMDDCDL_01146 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHMDDCDL_01147 1.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
GHMDDCDL_01148 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHMDDCDL_01149 0.0 asnB 6.3.5.4 E Asparagine synthase
GHMDDCDL_01150 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GHMDDCDL_01151 1.4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GHMDDCDL_01152 1.1e-130 jag S R3H domain protein
GHMDDCDL_01153 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHMDDCDL_01154 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GHMDDCDL_01155 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GHMDDCDL_01156 1.2e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GHMDDCDL_01157 2.6e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GHMDDCDL_01158 1.7e-34 yaaA S S4 domain protein YaaA
GHMDDCDL_01159 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GHMDDCDL_01160 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHMDDCDL_01161 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHMDDCDL_01162 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
GHMDDCDL_01163 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GHMDDCDL_01164 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHMDDCDL_01171 1.9e-142 L Belongs to the 'phage' integrase family
GHMDDCDL_01172 2e-91 K AntA/AntB antirepressor
GHMDDCDL_01173 1.7e-11
GHMDDCDL_01175 8.3e-66 3.4.21.88 K Peptidase S24-like
GHMDDCDL_01176 9.4e-14 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_01177 7.5e-39
GHMDDCDL_01180 1.2e-29
GHMDDCDL_01181 7e-78 S Siphovirus Gp157
GHMDDCDL_01182 1.1e-256 res L Helicase C-terminal domain protein
GHMDDCDL_01183 2.7e-140 L AAA domain
GHMDDCDL_01184 3.7e-93
GHMDDCDL_01185 3.3e-149 S Bifunctional DNA primase/polymerase, N-terminal
GHMDDCDL_01186 3.6e-227 S Virulence-associated protein E
GHMDDCDL_01187 2e-18 xre K Transcriptional
GHMDDCDL_01188 1.1e-58 S VRR_NUC
GHMDDCDL_01196 1e-78 arpU S Phage transcriptional regulator, ArpU family
GHMDDCDL_01198 4.3e-37 L Terminase small subunit
GHMDDCDL_01200 5.7e-244 S Phage terminase, large subunit
GHMDDCDL_01201 1.2e-269 S Phage portal protein
GHMDDCDL_01202 1.5e-235 S Phage Mu protein F like protein
GHMDDCDL_01204 1.7e-33 S YjcQ protein
GHMDDCDL_01205 8.9e-102 S Domain of unknown function (DUF4355)
GHMDDCDL_01206 1e-154
GHMDDCDL_01207 1.3e-64 S Phage gp6-like head-tail connector protein
GHMDDCDL_01208 9.1e-50
GHMDDCDL_01209 4.2e-68 S Bacteriophage HK97-gp10, putative tail-component
GHMDDCDL_01210 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
GHMDDCDL_01211 1.5e-172 malR K Transcriptional regulator, LacI family
GHMDDCDL_01212 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHMDDCDL_01213 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GHMDDCDL_01214 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHMDDCDL_01215 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
GHMDDCDL_01217 0.0 clpL O associated with various cellular activities
GHMDDCDL_01218 7.8e-32
GHMDDCDL_01219 1.8e-215 patA 2.6.1.1 E Aminotransferase
GHMDDCDL_01220 1.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHMDDCDL_01221 5e-75 osmC O OsmC-like protein
GHMDDCDL_01222 1.1e-256 malT G Major Facilitator
GHMDDCDL_01223 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GHMDDCDL_01224 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GHMDDCDL_01225 1e-76
GHMDDCDL_01226 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
GHMDDCDL_01227 3.3e-118 K response regulator
GHMDDCDL_01228 3.1e-226 sptS 2.7.13.3 T Histidine kinase
GHMDDCDL_01229 1e-215 yfeO P Voltage gated chloride channel
GHMDDCDL_01230 3.1e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GHMDDCDL_01231 1.5e-135 puuD S peptidase C26
GHMDDCDL_01232 6.6e-167 yvgN C Aldo keto reductase
GHMDDCDL_01233 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
GHMDDCDL_01234 3e-87 hmpT S ECF-type riboflavin transporter, S component
GHMDDCDL_01235 4.9e-262 nox C NADH oxidase
GHMDDCDL_01236 1.2e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GHMDDCDL_01237 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GHMDDCDL_01238 9.1e-59
GHMDDCDL_01239 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHMDDCDL_01241 1.1e-13 steT_1 E amino acid
GHMDDCDL_01242 2.1e-12 K Transcriptional regulator, TetR family
GHMDDCDL_01243 1.5e-74 K Transcriptional regulator, TetR family
GHMDDCDL_01245 1.9e-43
GHMDDCDL_01246 2.7e-109 S CAAX protease self-immunity
GHMDDCDL_01247 1.8e-31
GHMDDCDL_01248 6.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHMDDCDL_01249 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
GHMDDCDL_01250 2.2e-113
GHMDDCDL_01251 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
GHMDDCDL_01252 8.3e-177 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GHMDDCDL_01253 7.3e-86 uspA T Belongs to the universal stress protein A family
GHMDDCDL_01254 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
GHMDDCDL_01255 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHMDDCDL_01256 1.1e-300 ytgP S Polysaccharide biosynthesis protein
GHMDDCDL_01257 7.6e-42
GHMDDCDL_01258 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHMDDCDL_01259 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GHMDDCDL_01260 3e-93 tag 3.2.2.20 L glycosylase
GHMDDCDL_01261 1e-257 EGP Major facilitator Superfamily
GHMDDCDL_01262 2.8e-84 perR P Belongs to the Fur family
GHMDDCDL_01263 5.9e-231 cycA E Amino acid permease
GHMDDCDL_01264 1.2e-100 V VanZ like family
GHMDDCDL_01265 1e-23
GHMDDCDL_01266 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHMDDCDL_01267 1.2e-39
GHMDDCDL_01268 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
GHMDDCDL_01269 4.6e-36 K Bacterial transcriptional regulator
GHMDDCDL_01270 5.9e-71 IQ Enoyl-(Acyl carrier protein) reductase
GHMDDCDL_01271 5.3e-273 S C4-dicarboxylate anaerobic carrier
GHMDDCDL_01272 1.8e-246 nhaC C Na H antiporter NhaC
GHMDDCDL_01273 1.6e-241 pbuX F xanthine permease
GHMDDCDL_01274 2.3e-278 pipD E Dipeptidase
GHMDDCDL_01275 2.8e-168 corA P CorA-like Mg2+ transporter protein
GHMDDCDL_01276 6.3e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHMDDCDL_01277 6.6e-131 terC P membrane
GHMDDCDL_01278 1.5e-55 trxA O Belongs to the thioredoxin family
GHMDDCDL_01279 9.5e-234 mepA V MATE efflux family protein
GHMDDCDL_01280 9.9e-55 K Transcriptional regulator, ArsR family
GHMDDCDL_01281 5.1e-96 P Cadmium resistance transporter
GHMDDCDL_01282 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
GHMDDCDL_01283 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GHMDDCDL_01284 4.1e-181 ABC-SBP S ABC transporter
GHMDDCDL_01285 5.2e-53 ywiB S Domain of unknown function (DUF1934)
GHMDDCDL_01286 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GHMDDCDL_01287 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GHMDDCDL_01288 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHMDDCDL_01289 4.6e-41 rpmE2 J Ribosomal protein L31
GHMDDCDL_01290 7.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHMDDCDL_01291 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
GHMDDCDL_01292 7.3e-116 srtA 3.4.22.70 M sortase family
GHMDDCDL_01293 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GHMDDCDL_01294 1.6e-159 3.2.1.55 GH51 G Right handed beta helix region
GHMDDCDL_01295 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHMDDCDL_01296 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GHMDDCDL_01297 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GHMDDCDL_01298 3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHMDDCDL_01299 2e-92 lemA S LemA family
GHMDDCDL_01300 2e-158 htpX O Belongs to the peptidase M48B family
GHMDDCDL_01301 1.9e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GHMDDCDL_01302 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GHMDDCDL_01303 3.4e-94 K Acetyltransferase (GNAT) family
GHMDDCDL_01304 2e-76 K LytTr DNA-binding domain
GHMDDCDL_01305 1.5e-66 S Protein of unknown function (DUF3021)
GHMDDCDL_01306 1e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
GHMDDCDL_01307 4.2e-171 XK27_00915 C Luciferase-like monooxygenase
GHMDDCDL_01308 1.6e-108 pnb C nitroreductase
GHMDDCDL_01309 1.7e-91
GHMDDCDL_01310 4.3e-83 yvbK 3.1.3.25 K GNAT family
GHMDDCDL_01311 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
GHMDDCDL_01312 3.1e-204 amtB P ammonium transporter
GHMDDCDL_01313 9.2e-89 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GHMDDCDL_01315 1.7e-148 S PFAM Archaeal ATPase
GHMDDCDL_01316 0.0 XK27_08510 L Type III restriction protein res subunit
GHMDDCDL_01317 8.5e-43
GHMDDCDL_01318 2.5e-155 cylA V ABC transporter
GHMDDCDL_01319 1.2e-141 cylB V ABC-2 type transporter
GHMDDCDL_01320 3.2e-72 K LytTr DNA-binding domain
GHMDDCDL_01321 6.3e-61 S Protein of unknown function (DUF3021)
GHMDDCDL_01323 4.3e-127 L Plasmid pRiA4b ORF-3-like protein
GHMDDCDL_01324 2.6e-10 L Plasmid pRiA4b ORF-3-like protein
GHMDDCDL_01325 3e-96 yslB S Protein of unknown function (DUF2507)
GHMDDCDL_01326 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GHMDDCDL_01327 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GHMDDCDL_01328 3.4e-94 S Phosphoesterase
GHMDDCDL_01329 1.1e-74 ykuL S (CBS) domain
GHMDDCDL_01330 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
GHMDDCDL_01331 6.9e-148 ykuT M mechanosensitive ion channel
GHMDDCDL_01332 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GHMDDCDL_01333 4.3e-16
GHMDDCDL_01334 2.3e-209 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GHMDDCDL_01335 1e-179 ccpA K catabolite control protein A
GHMDDCDL_01336 3e-132
GHMDDCDL_01337 5.9e-132 yebC K Transcriptional regulatory protein
GHMDDCDL_01338 4.8e-182 comGA NU Type II IV secretion system protein
GHMDDCDL_01339 4.3e-181 comGB NU type II secretion system
GHMDDCDL_01340 7.1e-47 comGC U competence protein ComGC
GHMDDCDL_01341 2.4e-77 NU general secretion pathway protein
GHMDDCDL_01342 7.9e-40
GHMDDCDL_01343 2e-68
GHMDDCDL_01345 9.4e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
GHMDDCDL_01346 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHMDDCDL_01347 6.1e-111 S Calcineurin-like phosphoesterase
GHMDDCDL_01348 6.6e-93 yutD S Protein of unknown function (DUF1027)
GHMDDCDL_01349 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GHMDDCDL_01350 2.8e-101 S Protein of unknown function (DUF1461)
GHMDDCDL_01351 1.6e-109 dedA S SNARE-like domain protein
GHMDDCDL_01352 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GHMDDCDL_01353 3.3e-103 T Ion transport 2 domain protein
GHMDDCDL_01354 0.0 S Bacterial membrane protein YfhO
GHMDDCDL_01355 2.9e-197 G Transporter, major facilitator family protein
GHMDDCDL_01356 7.3e-106 yvrI K sigma factor activity
GHMDDCDL_01357 3e-60 ydiI Q Thioesterase superfamily
GHMDDCDL_01358 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GHMDDCDL_01359 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GHMDDCDL_01360 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GHMDDCDL_01361 2.8e-31 feoA P FeoA domain
GHMDDCDL_01362 1.9e-144 sufC O FeS assembly ATPase SufC
GHMDDCDL_01363 1.7e-240 sufD O FeS assembly protein SufD
GHMDDCDL_01364 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHMDDCDL_01365 1.2e-79 nifU C SUF system FeS assembly protein, NifU family
GHMDDCDL_01366 1.2e-271 sufB O assembly protein SufB
GHMDDCDL_01367 1.1e-56 yitW S Iron-sulfur cluster assembly protein
GHMDDCDL_01368 5.2e-159 hipB K Helix-turn-helix
GHMDDCDL_01369 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
GHMDDCDL_01370 3.5e-94 K Transcriptional regulator (TetR family)
GHMDDCDL_01371 3.4e-220 V domain protein
GHMDDCDL_01372 1.5e-156 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHMDDCDL_01374 6.6e-35 S Transglycosylase associated protein
GHMDDCDL_01375 2e-220 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHMDDCDL_01376 1.5e-126 3.1.3.73 G phosphoglycerate mutase
GHMDDCDL_01377 4e-116 dedA S SNARE associated Golgi protein
GHMDDCDL_01378 0.0 helD 3.6.4.12 L DNA helicase
GHMDDCDL_01379 1.3e-36 Q pyridine nucleotide-disulphide oxidoreductase
GHMDDCDL_01380 2.5e-158 EG EamA-like transporter family
GHMDDCDL_01381 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHMDDCDL_01382 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
GHMDDCDL_01383 5e-218 S cog cog1373
GHMDDCDL_01385 1.1e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GHMDDCDL_01387 2.1e-39 yabO J S4 domain protein
GHMDDCDL_01388 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHMDDCDL_01389 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GHMDDCDL_01390 1.1e-113 S (CBS) domain
GHMDDCDL_01391 6.4e-145 tesE Q hydratase
GHMDDCDL_01392 8.9e-242 codA 3.5.4.1 F cytosine deaminase
GHMDDCDL_01393 2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
GHMDDCDL_01394 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
GHMDDCDL_01395 1.1e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHMDDCDL_01396 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GHMDDCDL_01398 5.5e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHMDDCDL_01399 6.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
GHMDDCDL_01400 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHMDDCDL_01401 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GHMDDCDL_01402 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
GHMDDCDL_01403 8.4e-69
GHMDDCDL_01404 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GHMDDCDL_01405 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GHMDDCDL_01406 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
GHMDDCDL_01407 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHMDDCDL_01408 5.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
GHMDDCDL_01409 5.6e-214 folP 2.5.1.15 H dihydropteroate synthase
GHMDDCDL_01410 1.4e-43
GHMDDCDL_01411 1.3e-36
GHMDDCDL_01413 4.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHMDDCDL_01414 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GHMDDCDL_01415 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GHMDDCDL_01416 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GHMDDCDL_01417 2.7e-37 yheA S Belongs to the UPF0342 family
GHMDDCDL_01418 1.1e-220 yhaO L Ser Thr phosphatase family protein
GHMDDCDL_01419 0.0 L AAA domain
GHMDDCDL_01420 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GHMDDCDL_01421 3.3e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHMDDCDL_01422 7.9e-100 IQ KR domain
GHMDDCDL_01423 3.5e-96 eutJ E Hsp70 protein
GHMDDCDL_01424 1.5e-56 K helix_turn_helix, arabinose operon control protein
GHMDDCDL_01425 8.9e-33 pduA_4 CQ BMC
GHMDDCDL_01426 2.7e-89 pduB E BMC
GHMDDCDL_01427 3e-253 pduC 4.2.1.28 Q Dehydratase large subunit
GHMDDCDL_01428 2.1e-78 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
GHMDDCDL_01429 2.8e-48 pduE 4.2.1.28 Q Dehydratase small subunit
GHMDDCDL_01430 1.7e-273 pduG D Diol dehydratase reactivase ATPase-like domain
GHMDDCDL_01431 3.6e-31 pduH S Dehydratase medium subunit
GHMDDCDL_01432 4.3e-31 pduK CQ BMC
GHMDDCDL_01433 3.9e-34 pduA_4 CQ BMC
GHMDDCDL_01434 5.2e-47 S Putative propanediol utilisation
GHMDDCDL_01435 9.8e-32 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
GHMDDCDL_01436 3.3e-77 pduO 2.5.1.17 S Cobalamin adenosyltransferase
GHMDDCDL_01437 7.9e-50 pduO S Haem-degrading
GHMDDCDL_01439 1.9e-48 pduU E BMC
GHMDDCDL_01440 4.9e-60 3.1.3.48 T Pfam:Y_phosphatase3C
GHMDDCDL_01441 9.1e-14 P Cadmium resistance transporter
GHMDDCDL_01442 6.1e-49 eutP E Ethanolamine utilisation - propanediol utilisation
GHMDDCDL_01443 5.8e-65 XK27_04590 S NADPH-dependent FMN reductase
GHMDDCDL_01444 6.5e-72 S Abortive infection C-terminus
GHMDDCDL_01445 2.5e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHMDDCDL_01446 1e-187 yegS 2.7.1.107 G Lipid kinase
GHMDDCDL_01447 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHMDDCDL_01448 1.6e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GHMDDCDL_01449 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHMDDCDL_01450 1.2e-202 camS S sex pheromone
GHMDDCDL_01451 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GHMDDCDL_01452 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GHMDDCDL_01453 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GHMDDCDL_01454 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GHMDDCDL_01455 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
GHMDDCDL_01456 8e-140 IQ reductase
GHMDDCDL_01457 0.0 FbpA K Fibronectin-binding protein
GHMDDCDL_01458 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHMDDCDL_01459 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
GHMDDCDL_01460 1.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHMDDCDL_01461 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GHMDDCDL_01462 5.6e-65 esbA S Family of unknown function (DUF5322)
GHMDDCDL_01463 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
GHMDDCDL_01464 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GHMDDCDL_01465 8.8e-81 F Belongs to the NrdI family
GHMDDCDL_01466 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GHMDDCDL_01467 3.2e-101 ypsA S Belongs to the UPF0398 family
GHMDDCDL_01468 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GHMDDCDL_01469 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GHMDDCDL_01470 1.3e-160 EG EamA-like transporter family
GHMDDCDL_01471 8.1e-123 dnaD L DnaD domain protein
GHMDDCDL_01472 9.9e-86 ypmB S Protein conserved in bacteria
GHMDDCDL_01473 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GHMDDCDL_01474 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GHMDDCDL_01475 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GHMDDCDL_01476 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GHMDDCDL_01477 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHMDDCDL_01478 9.3e-86 S Protein of unknown function (DUF1440)
GHMDDCDL_01479 1.9e-253 G PTS system Galactitol-specific IIC component
GHMDDCDL_01480 2.6e-211 EGP Major facilitator Superfamily
GHMDDCDL_01481 1.8e-135 V ABC transporter
GHMDDCDL_01482 4.3e-97
GHMDDCDL_01483 4e-14
GHMDDCDL_01484 7.1e-63
GHMDDCDL_01485 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
GHMDDCDL_01486 6.6e-81 uspA T universal stress protein
GHMDDCDL_01487 0.0 tetP J elongation factor G
GHMDDCDL_01488 2.9e-165 GK ROK family
GHMDDCDL_01489 3.2e-237 brnQ U Component of the transport system for branched-chain amino acids
GHMDDCDL_01490 2.7e-137 aroD S Serine hydrolase (FSH1)
GHMDDCDL_01491 1.2e-80 yagE E amino acid
GHMDDCDL_01492 2.2e-144 yagE E amino acid
GHMDDCDL_01493 1.1e-49 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHMDDCDL_01494 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
GHMDDCDL_01495 3.8e-16 L nuclease
GHMDDCDL_01496 0.0 sbcC L Putative exonuclease SbcCD, C subunit
GHMDDCDL_01497 6.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GHMDDCDL_01498 6.3e-145 ywqE 3.1.3.48 GM PHP domain protein
GHMDDCDL_01499 0.0 snf 2.7.11.1 KL domain protein
GHMDDCDL_01501 8.9e-37
GHMDDCDL_01502 5e-35 T Toxin-antitoxin system, toxin component, MazF family
GHMDDCDL_01503 1.2e-120 GM NmrA-like family
GHMDDCDL_01504 1.8e-50 hxlR K Transcriptional regulator, HxlR family
GHMDDCDL_01505 4.1e-107 XK27_02070 S Nitroreductase family
GHMDDCDL_01506 1.2e-82 K Transcriptional regulator, HxlR family
GHMDDCDL_01507 2.5e-223
GHMDDCDL_01508 2.2e-210 EGP Major facilitator Superfamily
GHMDDCDL_01509 1.5e-255 pepC 3.4.22.40 E aminopeptidase
GHMDDCDL_01510 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
GHMDDCDL_01511 0.0 pepN 3.4.11.2 E aminopeptidase
GHMDDCDL_01512 5.5e-48 K Transcriptional regulator
GHMDDCDL_01513 6.1e-39 folT S ECF transporter, substrate-specific component
GHMDDCDL_01514 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
GHMDDCDL_01515 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GHMDDCDL_01516 9.4e-118 L Integrase
GHMDDCDL_01517 3e-156 rssA S Phospholipase, patatin family
GHMDDCDL_01518 2.3e-294 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GHMDDCDL_01519 1.6e-199 xerS L Belongs to the 'phage' integrase family
GHMDDCDL_01521 2.3e-69 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GHMDDCDL_01522 1.3e-76 marR K Transcriptional regulator, MarR family
GHMDDCDL_01523 6e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GHMDDCDL_01524 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHMDDCDL_01525 3.8e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GHMDDCDL_01526 1.3e-123 IQ reductase
GHMDDCDL_01527 7.8e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GHMDDCDL_01528 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GHMDDCDL_01529 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GHMDDCDL_01530 7.8e-244 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GHMDDCDL_01531 1.2e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GHMDDCDL_01532 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GHMDDCDL_01533 7.4e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GHMDDCDL_01542 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GHMDDCDL_01543 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
GHMDDCDL_01544 0.0 pacL 3.6.3.8 P P-type ATPase
GHMDDCDL_01545 3.4e-85 dps P Belongs to the Dps family
GHMDDCDL_01546 1.8e-51 yagE E amino acid
GHMDDCDL_01547 3e-54 yagE E amino acid
GHMDDCDL_01548 1e-108 yagE E amino acid
GHMDDCDL_01549 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
GHMDDCDL_01550 2.7e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GHMDDCDL_01551 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GHMDDCDL_01552 6.4e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GHMDDCDL_01553 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
GHMDDCDL_01554 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHMDDCDL_01555 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GHMDDCDL_01556 1e-259 G Major Facilitator
GHMDDCDL_01557 1.3e-174 K Transcriptional regulator, LacI family
GHMDDCDL_01558 6.1e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHMDDCDL_01559 2.4e-101 nqr 1.5.1.36 S reductase
GHMDDCDL_01560 4.2e-199 XK27_09615 S reductase
GHMDDCDL_01561 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHMDDCDL_01562 3e-27 L PFAM transposase IS200-family protein
GHMDDCDL_01563 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GHMDDCDL_01564 6.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GHMDDCDL_01565 5.7e-264 glnP P ABC transporter
GHMDDCDL_01566 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHMDDCDL_01567 6.1e-220 cycA E Amino acid permease
GHMDDCDL_01568 3.3e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GHMDDCDL_01569 3.9e-173 scrR K Transcriptional regulator, LacI family
GHMDDCDL_01570 1e-24
GHMDDCDL_01571 7.6e-101
GHMDDCDL_01572 4.1e-212 yttB EGP Major facilitator Superfamily
GHMDDCDL_01573 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
GHMDDCDL_01574 1.1e-86
GHMDDCDL_01575 3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
GHMDDCDL_01576 2.5e-261 S Putative peptidoglycan binding domain
GHMDDCDL_01577 1.7e-122 yciB M ErfK YbiS YcfS YnhG
GHMDDCDL_01579 1.3e-97
GHMDDCDL_01580 1.6e-73 elaA S Gnat family
GHMDDCDL_01581 5.7e-36 S Cytochrome B5
GHMDDCDL_01582 1.3e-218 yxjG_1 E methionine synthase, vitamin-B12 independent
GHMDDCDL_01584 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GHMDDCDL_01585 2.3e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GHMDDCDL_01586 5.1e-238 E amino acid
GHMDDCDL_01587 2.8e-31 npp S type I phosphodiesterase nucleotide pyrophosphatase
GHMDDCDL_01588 1.7e-47 npp S type I phosphodiesterase nucleotide pyrophosphatase
GHMDDCDL_01589 1.1e-101 npp S type I phosphodiesterase nucleotide pyrophosphatase
GHMDDCDL_01590 2.4e-201 yxiO S Vacuole effluxer Atg22 like
GHMDDCDL_01593 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHMDDCDL_01594 3.5e-30
GHMDDCDL_01597 3.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GHMDDCDL_01598 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GHMDDCDL_01599 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
GHMDDCDL_01600 0.0 trxB2 1.8.1.9 C Thioredoxin domain
GHMDDCDL_01601 4.9e-273 pipD E Dipeptidase
GHMDDCDL_01602 6.4e-297 yjbQ P TrkA C-terminal domain protein
GHMDDCDL_01603 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GHMDDCDL_01604 1.1e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GHMDDCDL_01605 1.9e-81
GHMDDCDL_01606 4.7e-35
GHMDDCDL_01607 2.3e-08 K Transcriptional regulator, HxlR family
GHMDDCDL_01608 2.5e-40 S Acyltransferase family
GHMDDCDL_01609 2.3e-34 S Peptidase_C39 like family
GHMDDCDL_01610 3.1e-61 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GHMDDCDL_01611 5.8e-105 S Psort location CytoplasmicMembrane, score
GHMDDCDL_01612 1.3e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GHMDDCDL_01613 1.3e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GHMDDCDL_01614 1.3e-162 yueF S AI-2E family transporter
GHMDDCDL_01615 2.4e-24
GHMDDCDL_01616 1.3e-54 M repeat protein
GHMDDCDL_01617 1.9e-66 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GHMDDCDL_01618 0.0 rafA 3.2.1.22 G alpha-galactosidase
GHMDDCDL_01619 9.7e-186 galR K Periplasmic binding protein-like domain
GHMDDCDL_01620 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
GHMDDCDL_01621 6.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHMDDCDL_01622 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
GHMDDCDL_01623 4e-148 f42a O Band 7 protein
GHMDDCDL_01624 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GHMDDCDL_01625 1e-153 yitU 3.1.3.104 S hydrolase
GHMDDCDL_01626 9.2e-39 S Cytochrome B5
GHMDDCDL_01627 2.1e-103 nreC K PFAM regulatory protein LuxR
GHMDDCDL_01628 2.7e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
GHMDDCDL_01629 3.2e-59 yneR
GHMDDCDL_01630 7.5e-99 qorB 1.6.5.2 GM NmrA-like family
GHMDDCDL_01631 1.6e-160 akr5f 1.1.1.346 S reductase
GHMDDCDL_01632 7.6e-147 K Transcriptional regulator
GHMDDCDL_01633 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
GHMDDCDL_01634 6.6e-163 ypuA S Protein of unknown function (DUF1002)
GHMDDCDL_01635 2.4e-228 aadAT EK Aminotransferase, class I
GHMDDCDL_01636 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GHMDDCDL_01637 6e-154 tesE Q hydratase
GHMDDCDL_01638 1.4e-34 S Alpha beta hydrolase
GHMDDCDL_01639 7.5e-81 lytE M LysM domain protein
GHMDDCDL_01640 0.0 oppD EP Psort location Cytoplasmic, score
GHMDDCDL_01641 2e-42 lytE M LysM domain protein
GHMDDCDL_01642 1.2e-158 sufD O Uncharacterized protein family (UPF0051)
GHMDDCDL_01643 2.4e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHMDDCDL_01644 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GHMDDCDL_01645 5e-233 lmrB EGP Major facilitator Superfamily
GHMDDCDL_01646 4.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
GHMDDCDL_01648 2.1e-07 V CAAX protease self-immunity
GHMDDCDL_01649 1.1e-29
GHMDDCDL_01652 1.9e-77 S Fic/DOC family
GHMDDCDL_01653 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GHMDDCDL_01654 4.8e-51 S Iron-sulfur cluster assembly protein
GHMDDCDL_01655 9.7e-150
GHMDDCDL_01656 2e-178
GHMDDCDL_01657 8.2e-85 dut S Protein conserved in bacteria
GHMDDCDL_01661 6.4e-111 K Transcriptional regulator
GHMDDCDL_01662 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
GHMDDCDL_01663 2.4e-53 ysxB J Cysteine protease Prp
GHMDDCDL_01664 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GHMDDCDL_01665 1.2e-255 ganB 3.2.1.89 G arabinogalactan
GHMDDCDL_01666 4e-60 M Peptidase_C39 like family
GHMDDCDL_01669 6.1e-110 S Peptidase, M23
GHMDDCDL_01670 3.6e-14 D nuclear chromosome segregation
GHMDDCDL_01671 1.2e-64 gntR1 K Transcriptional regulator, GntR family
GHMDDCDL_01672 1.2e-155 V ABC transporter, ATP-binding protein
GHMDDCDL_01673 1.9e-116
GHMDDCDL_01674 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GHMDDCDL_01675 3.5e-98 S Pfam:DUF3816
GHMDDCDL_01676 0.0 clpE O Belongs to the ClpA ClpB family
GHMDDCDL_01677 2.9e-27
GHMDDCDL_01678 9.6e-295 lmrA V ABC transporter, ATP-binding protein
GHMDDCDL_01679 0.0 yfiC V ABC transporter
GHMDDCDL_01680 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
GHMDDCDL_01681 2.6e-269 pipD E Dipeptidase
GHMDDCDL_01682 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHMDDCDL_01683 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
GHMDDCDL_01684 7e-136 XK27_01040 S Protein of unknown function (DUF1129)
GHMDDCDL_01685 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GHMDDCDL_01686 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
GHMDDCDL_01687 5.5e-153 spo0J K Belongs to the ParB family
GHMDDCDL_01688 3.6e-140 soj D Sporulation initiation inhibitor
GHMDDCDL_01689 1.9e-143 noc K Belongs to the ParB family
GHMDDCDL_01690 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GHMDDCDL_01691 1.1e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GHMDDCDL_01692 1.9e-169 rihC 3.2.2.1 F Nucleoside
GHMDDCDL_01693 1.3e-218 nupG F Nucleoside transporter
GHMDDCDL_01694 2.4e-220 patA 2.6.1.1 E Aminotransferase
GHMDDCDL_01695 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
GHMDDCDL_01696 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GHMDDCDL_01697 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GHMDDCDL_01698 2e-29 S Protein of unknown function (DUF2929)
GHMDDCDL_01699 0.0 dnaE 2.7.7.7 L DNA polymerase
GHMDDCDL_01700 2.2e-72
GHMDDCDL_01701 5.3e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
GHMDDCDL_01702 2.2e-271 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
GHMDDCDL_01703 1.8e-277 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
GHMDDCDL_01704 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
GHMDDCDL_01705 3.7e-265 G Major Facilitator
GHMDDCDL_01706 4.1e-50 czrA K Transcriptional regulator, ArsR family
GHMDDCDL_01707 2.5e-36
GHMDDCDL_01708 0.0 yhcA V ABC transporter, ATP-binding protein
GHMDDCDL_01709 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GHMDDCDL_01710 2.1e-167 hrtB V ABC transporter permease
GHMDDCDL_01711 2.4e-84 ygfC K transcriptional regulator (TetR family)
GHMDDCDL_01712 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GHMDDCDL_01713 1.2e-286 mntH P H( )-stimulated, divalent metal cation uptake system
GHMDDCDL_01714 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GHMDDCDL_01715 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GHMDDCDL_01716 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GHMDDCDL_01717 7.5e-194 coiA 3.6.4.12 S Competence protein
GHMDDCDL_01718 6.6e-262 pipD E Dipeptidase
GHMDDCDL_01719 3.1e-113 yjbH Q Thioredoxin
GHMDDCDL_01720 2.3e-111 yjbM 2.7.6.5 S RelA SpoT domain protein
GHMDDCDL_01721 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GHMDDCDL_01722 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GHMDDCDL_01723 4.6e-160
GHMDDCDL_01724 1e-72 K Transcriptional regulator
GHMDDCDL_01725 1.1e-186 D Alpha beta
GHMDDCDL_01726 1.4e-51 ypaA S Protein of unknown function (DUF1304)
GHMDDCDL_01727 0.0 yjcE P Sodium proton antiporter
GHMDDCDL_01728 3.6e-52 yvlA
GHMDDCDL_01729 3.9e-111 P Cobalt transport protein
GHMDDCDL_01730 8.4e-249 cbiO1 S ABC transporter, ATP-binding protein
GHMDDCDL_01731 7.9e-97 S ABC-type cobalt transport system, permease component
GHMDDCDL_01732 6.5e-85 S Short repeat of unknown function (DUF308)
GHMDDCDL_01733 2.5e-77 S Psort location Cytoplasmic, score
GHMDDCDL_01734 7.4e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
GHMDDCDL_01735 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
GHMDDCDL_01736 2.6e-152 yeaE S Aldo keto
GHMDDCDL_01737 5.8e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
GHMDDCDL_01738 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GHMDDCDL_01739 1.1e-109 xth 3.1.11.2 L exodeoxyribonuclease III
GHMDDCDL_01740 2.3e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHMDDCDL_01741 1.2e-102 pncA Q Isochorismatase family
GHMDDCDL_01742 2.7e-103 K transcriptional regulator
GHMDDCDL_01743 2.2e-297 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GHMDDCDL_01744 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
GHMDDCDL_01745 1.4e-98 dps P Belongs to the Dps family
GHMDDCDL_01746 4.9e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
GHMDDCDL_01749 2.9e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GHMDDCDL_01750 2.6e-253 nhaC C Na H antiporter NhaC
GHMDDCDL_01751 2.5e-36 S Cytochrome b5-like Heme/Steroid binding domain
GHMDDCDL_01752 1.2e-112 ywnB S NAD(P)H-binding
GHMDDCDL_01753 3.2e-36
GHMDDCDL_01754 3e-128 IQ Dehydrogenase reductase
GHMDDCDL_01755 2e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
GHMDDCDL_01757 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
GHMDDCDL_01758 2.3e-215 nusA K Participates in both transcription termination and antitermination
GHMDDCDL_01759 1e-44 ylxR K Protein of unknown function (DUF448)
GHMDDCDL_01760 1.3e-48 ylxQ J ribosomal protein
GHMDDCDL_01761 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHMDDCDL_01762 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GHMDDCDL_01763 2.7e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GHMDDCDL_01764 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GHMDDCDL_01765 2.9e-63
GHMDDCDL_01766 6.1e-49 yjmB G MFS/sugar transport protein
GHMDDCDL_01767 5.4e-96 exuR K Periplasmic binding protein domain
GHMDDCDL_01768 8.5e-21 1.1.1.346 C Aldo keto reductase
GHMDDCDL_01769 8.1e-81 1.1.1.346 C Aldo keto reductase
GHMDDCDL_01770 2.1e-39 gcvR T Belongs to the UPF0237 family
GHMDDCDL_01771 4.5e-239 XK27_08635 S UPF0210 protein
GHMDDCDL_01772 1.5e-94 K Acetyltransferase (GNAT) domain
GHMDDCDL_01773 2.8e-154 S Alpha beta hydrolase
GHMDDCDL_01774 8.7e-156 gspA M family 8
GHMDDCDL_01775 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHMDDCDL_01776 1.1e-89
GHMDDCDL_01777 2.1e-160 degV S EDD domain protein, DegV family
GHMDDCDL_01778 5.4e-53 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GHMDDCDL_01779 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
GHMDDCDL_01780 2.5e-121 fhuC P ABC transporter
GHMDDCDL_01781 8e-127 znuB U ABC 3 transport family
GHMDDCDL_01782 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GHMDDCDL_01783 3.5e-239 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHMDDCDL_01784 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHMDDCDL_01785 5.7e-228 clcA_2 P Chloride transporter, ClC family
GHMDDCDL_01786 4.8e-139 L PFAM transposase IS116 IS110 IS902
GHMDDCDL_01787 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GHMDDCDL_01788 3.2e-110 lssY 3.6.1.27 I Acid phosphatase homologues
GHMDDCDL_01789 9.5e-39 S Cytochrome B5
GHMDDCDL_01790 1.6e-37 L Helix-turn-helix domain
GHMDDCDL_01791 4.3e-121 O Zinc-dependent metalloprotease
GHMDDCDL_01792 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GHMDDCDL_01793 1.1e-145 metQ_4 P Belongs to the nlpA lipoprotein family
GHMDDCDL_01796 7.1e-150
GHMDDCDL_01797 4e-17 3.2.1.14 GH18
GHMDDCDL_01798 5.6e-82 zur P Belongs to the Fur family
GHMDDCDL_01799 1.5e-98 gmk2 2.7.4.8 F Guanylate kinase
GHMDDCDL_01800 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GHMDDCDL_01801 2.1e-252 yfnA E Amino Acid
GHMDDCDL_01802 5.7e-231 EGP Sugar (and other) transporter
GHMDDCDL_01803 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
GHMDDCDL_01804 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHMDDCDL_01805 3.8e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
GHMDDCDL_01806 1.4e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GHMDDCDL_01807 2e-280 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHMDDCDL_01808 4.8e-67 S Alpha beta hydrolase
GHMDDCDL_01809 4.9e-64 lacA S transferase hexapeptide repeat
GHMDDCDL_01810 1.5e-15 P nitric oxide dioxygenase activity
GHMDDCDL_01811 2.7e-104 S Peptidase propeptide and YPEB domain
GHMDDCDL_01812 6.7e-180 T GHKL domain
GHMDDCDL_01813 2.8e-23 T GHKL domain
GHMDDCDL_01814 5.3e-108 T Transcriptional regulatory protein, C terminal
GHMDDCDL_01815 1.3e-43 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
GHMDDCDL_01816 6.4e-58 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
GHMDDCDL_01817 2.3e-31
GHMDDCDL_01818 9.5e-18
GHMDDCDL_01819 1.5e-53
GHMDDCDL_01820 7.9e-34
GHMDDCDL_01821 6.2e-207 potD P ABC transporter
GHMDDCDL_01822 6.5e-140 potC P ABC transporter permease
GHMDDCDL_01823 3.9e-145 potB P ABC transporter permease
GHMDDCDL_01824 7.6e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GHMDDCDL_01825 3.5e-24
GHMDDCDL_01826 3.2e-53
GHMDDCDL_01827 9.7e-29
GHMDDCDL_01828 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GHMDDCDL_01829 2.3e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GHMDDCDL_01830 1.2e-103 fic D Fic/DOC family
GHMDDCDL_01831 4.3e-71
GHMDDCDL_01832 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHMDDCDL_01833 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
GHMDDCDL_01834 3.1e-223 mdtG EGP Major facilitator Superfamily
GHMDDCDL_01835 5.7e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GHMDDCDL_01836 5.7e-86 yxjG_1 E methionine synthase, vitamin-B12 independent
GHMDDCDL_01837 4.5e-92 D nuclear chromosome segregation
GHMDDCDL_01838 2.3e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GHMDDCDL_01839 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GHMDDCDL_01840 2.9e-190 V Beta-lactamase
GHMDDCDL_01841 6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHMDDCDL_01842 1.8e-98 yhiD S MgtC family
GHMDDCDL_01843 6.9e-22 S GyrI-like small molecule binding domain
GHMDDCDL_01844 2.4e-22 S GyrI-like small molecule binding domain
GHMDDCDL_01845 1.7e-106 L hmm pf00665
GHMDDCDL_01846 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
GHMDDCDL_01847 1e-270 ywfO S HD domain protein
GHMDDCDL_01848 2.3e-145 yxeH S hydrolase
GHMDDCDL_01849 9e-48
GHMDDCDL_01858 1.9e-11 K Cro/C1-type HTH DNA-binding domain
GHMDDCDL_01859 1.6e-23
GHMDDCDL_01861 1.6e-18
GHMDDCDL_01862 1.4e-15 S Hypothetical protein (DUF2513)
GHMDDCDL_01864 2.8e-216 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GHMDDCDL_01865 5e-28 S Alpha beta hydrolase
GHMDDCDL_01866 6e-64 S Alpha beta hydrolase
GHMDDCDL_01867 8.4e-207 gldA 1.1.1.6 C dehydrogenase
GHMDDCDL_01868 4.3e-13
GHMDDCDL_01869 1.7e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
GHMDDCDL_01870 2.4e-97 ltrA S Bacterial low temperature requirement A protein (LtrA)
GHMDDCDL_01871 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
GHMDDCDL_01872 6.8e-54
GHMDDCDL_01873 3.5e-112 frnE Q DSBA-like thioredoxin domain
GHMDDCDL_01874 2.3e-164 I alpha/beta hydrolase fold
GHMDDCDL_01875 1.1e-19 K Helix-turn-helix XRE-family like proteins
GHMDDCDL_01876 3.3e-35 S Phage derived protein Gp49-like (DUF891)
GHMDDCDL_01877 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GHMDDCDL_01878 1.9e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GHMDDCDL_01879 5.8e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GHMDDCDL_01880 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GHMDDCDL_01881 1.8e-53 L PFAM Integrase catalytic region
GHMDDCDL_01882 4e-67 L PFAM Integrase catalytic region
GHMDDCDL_01883 1e-32 L Helix-turn-helix domain
GHMDDCDL_01884 3.3e-133 S membrane transporter protein
GHMDDCDL_01885 5.3e-113 IQ KR domain
GHMDDCDL_01886 2e-09 IQ KR domain
GHMDDCDL_01887 2.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GHMDDCDL_01888 0.0 dnaK O Heat shock 70 kDa protein
GHMDDCDL_01889 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GHMDDCDL_01890 3.8e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GHMDDCDL_01891 1.2e-155 S Hydrolases of the alpha beta superfamily
GHMDDCDL_01892 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
GHMDDCDL_01893 4.4e-77 ctsR K Belongs to the CtsR family
GHMDDCDL_01894 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHMDDCDL_01895 3e-110 K Bacterial regulatory proteins, tetR family
GHMDDCDL_01896 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHMDDCDL_01897 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHMDDCDL_01898 7.5e-198 ykiI
GHMDDCDL_01899 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GHMDDCDL_01900 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GHMDDCDL_01901 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GHMDDCDL_01902 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GHMDDCDL_01903 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GHMDDCDL_01904 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GHMDDCDL_01905 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
GHMDDCDL_01906 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GHMDDCDL_01907 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GHMDDCDL_01908 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GHMDDCDL_01909 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GHMDDCDL_01910 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GHMDDCDL_01911 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GHMDDCDL_01912 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
GHMDDCDL_01913 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GHMDDCDL_01914 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GHMDDCDL_01915 4.4e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GHMDDCDL_01916 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GHMDDCDL_01917 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GHMDDCDL_01918 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GHMDDCDL_01919 4.2e-47 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GHMDDCDL_01920 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GHMDDCDL_01921 2.9e-24 rpmD J Ribosomal protein L30
GHMDDCDL_01922 1.5e-63 rplO J Binds to the 23S rRNA
GHMDDCDL_01923 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GHMDDCDL_01924 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHMDDCDL_01925 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GHMDDCDL_01926 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GHMDDCDL_01927 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GHMDDCDL_01928 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GHMDDCDL_01929 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHMDDCDL_01930 1.5e-62 rplQ J Ribosomal protein L17
GHMDDCDL_01931 1.2e-138 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHMDDCDL_01932 9.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHMDDCDL_01933 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHMDDCDL_01934 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GHMDDCDL_01935 2e-64 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GHMDDCDL_01936 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)