ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMHBALJH_00001 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HMHBALJH_00002 2.3e-179 ccpA K catabolite control protein A
HMHBALJH_00003 2.8e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMHBALJH_00004 2.5e-92 niaR S 3H domain
HMHBALJH_00005 1.9e-78 ytxH S YtxH-like protein
HMHBALJH_00007 1.8e-156 ykuT M mechanosensitive ion channel
HMHBALJH_00008 2.7e-155 XK27_00890 S Domain of unknown function (DUF368)
HMHBALJH_00009 8.7e-84 ykuL S CBS domain
HMHBALJH_00010 5.2e-133 gla U Major intrinsic protein
HMHBALJH_00011 4.1e-95 S Phosphoesterase
HMHBALJH_00012 5.3e-278 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMHBALJH_00013 1.2e-82 yslB S Protein of unknown function (DUF2507)
HMHBALJH_00014 5.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMHBALJH_00015 1.2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMHBALJH_00016 4.5e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HMHBALJH_00017 1.2e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMHBALJH_00018 6.6e-53 trxA O Belongs to the thioredoxin family
HMHBALJH_00019 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMHBALJH_00020 8.6e-93 cvpA S Colicin V production protein
HMHBALJH_00021 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMHBALJH_00022 2.3e-53 yrzB S Belongs to the UPF0473 family
HMHBALJH_00023 2.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMHBALJH_00024 4e-43 yrzL S Belongs to the UPF0297 family
HMHBALJH_00025 3.9e-209
HMHBALJH_00026 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMHBALJH_00027 4.3e-172
HMHBALJH_00028 5.6e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMHBALJH_00029 1.8e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMHBALJH_00030 5.2e-240 ytoI K DRTGG domain
HMHBALJH_00031 1.2e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMHBALJH_00032 1.1e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMHBALJH_00033 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
HMHBALJH_00034 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMHBALJH_00035 1.4e-45 yajC U Preprotein translocase
HMHBALJH_00036 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMHBALJH_00037 3.6e-207 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMHBALJH_00038 9e-195 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMHBALJH_00039 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMHBALJH_00040 3.5e-103 yjbF S SNARE associated Golgi protein
HMHBALJH_00041 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMHBALJH_00042 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMHBALJH_00043 3.5e-74 S Protein of unknown function (DUF3290)
HMHBALJH_00044 1e-116 yviA S Protein of unknown function (DUF421)
HMHBALJH_00045 2.8e-162 S Alpha beta hydrolase
HMHBALJH_00046 1.8e-120
HMHBALJH_00047 4.1e-158 dkgB S reductase
HMHBALJH_00048 3.8e-84 nrdI F Belongs to the NrdI family
HMHBALJH_00049 8e-179 D Alpha beta
HMHBALJH_00050 1.5e-77 K Transcriptional regulator
HMHBALJH_00051 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HMHBALJH_00052 2.9e-194 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMHBALJH_00053 1.1e-93 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMHBALJH_00054 1.8e-59
HMHBALJH_00055 1.8e-178 3.4.11.5 I Releases the N-terminal proline from various substrates
HMHBALJH_00056 0.0 yfgQ P E1-E2 ATPase
HMHBALJH_00057 1.8e-59
HMHBALJH_00058 2.5e-77 ndk 2.7.4.6 F Belongs to the NDK family
HMHBALJH_00059 0.0 pepF E Oligopeptidase F
HMHBALJH_00060 1.1e-284 V ABC transporter transmembrane region
HMHBALJH_00061 9.9e-172 K sequence-specific DNA binding
HMHBALJH_00062 3.4e-94
HMHBALJH_00063 1e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMHBALJH_00064 1.1e-170 mleP S Sodium Bile acid symporter family
HMHBALJH_00065 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HMHBALJH_00066 2.4e-161 mleR K LysR family
HMHBALJH_00067 8.6e-173 corA P CorA-like Mg2+ transporter protein
HMHBALJH_00068 8.8e-62 yeaO S Protein of unknown function, DUF488
HMHBALJH_00069 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMHBALJH_00070 8.8e-96
HMHBALJH_00071 2.7e-106 ywrF S Flavin reductase like domain
HMHBALJH_00072 1.1e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HMHBALJH_00073 3.2e-75
HMHBALJH_00074 1e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMHBALJH_00075 7.4e-26
HMHBALJH_00076 2.3e-207 yubA S AI-2E family transporter
HMHBALJH_00077 3.4e-80
HMHBALJH_00078 9.8e-56
HMHBALJH_00079 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMHBALJH_00080 6.6e-50
HMHBALJH_00081 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
HMHBALJH_00082 3.1e-56 K Transcriptional regulator PadR-like family
HMHBALJH_00083 5.4e-181 K sequence-specific DNA binding
HMHBALJH_00085 4.2e-06 mutR K Helix-turn-helix
HMHBALJH_00087 2.3e-07 Z012_04635 K Helix-turn-helix domain
HMHBALJH_00090 9.2e-206 lctO C IMP dehydrogenase / GMP reductase domain
HMHBALJH_00091 1.7e-122 drgA C Nitroreductase family
HMHBALJH_00092 1.7e-66 yqkB S Belongs to the HesB IscA family
HMHBALJH_00093 7.3e-239 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HMHBALJH_00094 1.3e-128 K cheY-homologous receiver domain
HMHBALJH_00095 6.4e-72 S GtrA-like protein
HMHBALJH_00096 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HMHBALJH_00097 4e-181 ykcC GT2 M Glycosyl transferase family 2
HMHBALJH_00098 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HMHBALJH_00099 1.1e-170 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HMHBALJH_00100 9.8e-141 cmpC S ABC transporter, ATP-binding protein
HMHBALJH_00101 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HMHBALJH_00102 2.6e-164 XK27_00670 S ABC transporter
HMHBALJH_00103 6.1e-166 XK27_00670 S ABC transporter substrate binding protein
HMHBALJH_00104 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
HMHBALJH_00105 4e-116 ywnB S NmrA-like family
HMHBALJH_00106 3.9e-07
HMHBALJH_00107 2.7e-199
HMHBALJH_00108 3e-153 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMHBALJH_00109 6.9e-87 S Short repeat of unknown function (DUF308)
HMHBALJH_00111 2.9e-120 yrkL S Flavodoxin-like fold
HMHBALJH_00112 1.9e-149 cytC6 I alpha/beta hydrolase fold
HMHBALJH_00113 1.6e-211 mutY L A G-specific adenine glycosylase
HMHBALJH_00114 5.3e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
HMHBALJH_00115 1.3e-14
HMHBALJH_00116 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HMHBALJH_00117 2.4e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMHBALJH_00118 5e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HMHBALJH_00119 1.9e-141 lacR K DeoR C terminal sensor domain
HMHBALJH_00120 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HMHBALJH_00121 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HMHBALJH_00122 1.6e-185 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HMHBALJH_00123 9.3e-175 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HMHBALJH_00124 1.4e-124 S Domain of unknown function (DUF4867)
HMHBALJH_00125 4.7e-188 V Beta-lactamase
HMHBALJH_00126 1.5e-29
HMHBALJH_00128 2.3e-249 gatC G PTS system sugar-specific permease component
HMHBALJH_00129 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_00130 4.3e-70 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_00132 6.9e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMHBALJH_00133 4.3e-162 K Transcriptional regulator
HMHBALJH_00134 1.1e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMHBALJH_00135 5.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMHBALJH_00136 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMHBALJH_00137 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_00138 4.7e-247 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_00139 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HMHBALJH_00140 6.5e-138 lacT K PRD domain
HMHBALJH_00141 5.2e-133 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HMHBALJH_00142 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMHBALJH_00143 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HMHBALJH_00144 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMHBALJH_00145 2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMHBALJH_00146 3.3e-276 mutS L ATPase domain of DNA mismatch repair MUTS family
HMHBALJH_00147 2.3e-311 ybiT S ABC transporter, ATP-binding protein
HMHBALJH_00148 1.2e-10
HMHBALJH_00150 2.7e-146 F DNA RNA non-specific endonuclease
HMHBALJH_00151 1.1e-118 yhiD S MgtC family
HMHBALJH_00152 1.4e-178 yfeX P Peroxidase
HMHBALJH_00153 1.3e-243 amt P ammonium transporter
HMHBALJH_00154 2e-158 3.5.1.10 C nadph quinone reductase
HMHBALJH_00155 1.1e-94 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HMHBALJH_00156 4.5e-52 ybjQ S Belongs to the UPF0145 family
HMHBALJH_00157 8.7e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HMHBALJH_00158 8.3e-145 S Alpha/beta hydrolase of unknown function (DUF915)
HMHBALJH_00159 1.4e-156 cylA V ABC transporter
HMHBALJH_00160 3.1e-148 cylB V ABC-2 type transporter
HMHBALJH_00161 4.8e-68 K LytTr DNA-binding domain
HMHBALJH_00162 2.2e-56 S Protein of unknown function (DUF3021)
HMHBALJH_00163 0.0 yjcE P Sodium proton antiporter
HMHBALJH_00164 1.4e-282 S Protein of unknown function (DUF3800)
HMHBALJH_00165 1.9e-256 yifK E Amino acid permease
HMHBALJH_00166 2.9e-159 yeaE S Aldo/keto reductase family
HMHBALJH_00167 1e-113 ylbE GM NAD(P)H-binding
HMHBALJH_00168 2.3e-281 lsa S ABC transporter
HMHBALJH_00169 3.5e-76 O OsmC-like protein
HMHBALJH_00170 4.1e-69
HMHBALJH_00171 4.6e-31 K 'Cold-shock' DNA-binding domain
HMHBALJH_00172 1.9e-250 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMHBALJH_00173 2.5e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMHBALJH_00174 2.5e-267 yfnA E Amino Acid
HMHBALJH_00175 2e-212 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMHBALJH_00176 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMHBALJH_00177 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HMHBALJH_00178 8.5e-128 treR K UTRA
HMHBALJH_00179 7.2e-220 oxlT P Major Facilitator Superfamily
HMHBALJH_00180 0.0 V ABC transporter
HMHBALJH_00181 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HMHBALJH_00182 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMHBALJH_00183 1.5e-163 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HMHBALJH_00184 6.1e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HMHBALJH_00185 6.2e-78 S ECF-type riboflavin transporter, S component
HMHBALJH_00186 1.1e-144 CcmA5 V ABC transporter
HMHBALJH_00187 2e-300
HMHBALJH_00188 1.1e-167 yicL EG EamA-like transporter family
HMHBALJH_00189 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HMHBALJH_00190 7.4e-113 N WxL domain surface cell wall-binding
HMHBALJH_00191 4.7e-61
HMHBALJH_00192 5e-120 S WxL domain surface cell wall-binding
HMHBALJH_00193 1.7e-133 L Transposase, IS116 IS110 IS902 family
HMHBALJH_00195 2.2e-245 XK27_00720 S Leucine-rich repeat (LRR) protein
HMHBALJH_00196 5.5e-43
HMHBALJH_00197 1.2e-172 S Cell surface protein
HMHBALJH_00198 3.5e-75 S WxL domain surface cell wall-binding
HMHBALJH_00199 2.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HMHBALJH_00200 2.2e-117
HMHBALJH_00201 2.2e-120 tcyB E ABC transporter
HMHBALJH_00202 8.6e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMHBALJH_00203 1e-212 metC 4.4.1.8 E cystathionine
HMHBALJH_00205 1.5e-138
HMHBALJH_00207 2.7e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMHBALJH_00208 5.1e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMHBALJH_00209 7.6e-91 S Protein of unknown function (DUF1440)
HMHBALJH_00210 2.2e-238 G MFS/sugar transport protein
HMHBALJH_00211 8.4e-276 ycaM E amino acid
HMHBALJH_00212 0.0 pepN 3.4.11.2 E aminopeptidase
HMHBALJH_00213 2.3e-105
HMHBALJH_00214 1.6e-197
HMHBALJH_00215 3.6e-160 V ATPases associated with a variety of cellular activities
HMHBALJH_00216 3.3e-195 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMHBALJH_00217 2.2e-125 K Transcriptional regulatory protein, C terminal
HMHBALJH_00218 6e-299 S Psort location CytoplasmicMembrane, score
HMHBALJH_00219 5.4e-130 XK27_12140 V ATPases associated with a variety of cellular activities
HMHBALJH_00220 1.1e-196
HMHBALJH_00221 1.8e-212 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HMHBALJH_00222 4.6e-38 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_00223 5.6e-188 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_00224 1.6e-29 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_00225 1.5e-248 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_00226 7.5e-61
HMHBALJH_00227 2e-127 S membrane transporter protein
HMHBALJH_00228 4e-59 hxlR K Transcriptional regulator, HxlR family
HMHBALJH_00229 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMHBALJH_00230 3.2e-161 morA2 S reductase
HMHBALJH_00231 2.5e-74 K helix_turn_helix, mercury resistance
HMHBALJH_00232 2.4e-248 E Amino acid permease
HMHBALJH_00233 1.5e-222 S Amidohydrolase
HMHBALJH_00234 5.3e-256 6.3.1.2 E Glutamine synthetase N-terminal domain
HMHBALJH_00235 1.3e-78 K Psort location Cytoplasmic, score
HMHBALJH_00236 1.3e-106 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HMHBALJH_00237 1.1e-139 puuD S peptidase C26
HMHBALJH_00238 8.7e-136 H Protein of unknown function (DUF1698)
HMHBALJH_00239 1.6e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMHBALJH_00240 7e-152 V Beta-lactamase
HMHBALJH_00241 3.4e-43
HMHBALJH_00242 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMHBALJH_00243 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMHBALJH_00244 2e-32
HMHBALJH_00245 1.2e-103 tag 3.2.2.20 L glycosylase
HMHBALJH_00246 4.8e-205 yceJ EGP Major facilitator Superfamily
HMHBALJH_00247 1.2e-48 K Helix-turn-helix domain
HMHBALJH_00248 7e-29
HMHBALJH_00249 6.5e-28 relB L RelB antitoxin
HMHBALJH_00250 2.2e-252 L Exonuclease
HMHBALJH_00251 5.2e-55
HMHBALJH_00253 2.9e-12
HMHBALJH_00254 1.9e-20
HMHBALJH_00255 2.6e-76 ohr O OsmC-like protein
HMHBALJH_00256 1.6e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HMHBALJH_00257 2.5e-101 dhaL 2.7.1.121 S Dak2
HMHBALJH_00258 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HMHBALJH_00259 4e-104 K Bacterial regulatory proteins, tetR family
HMHBALJH_00260 9.4e-17
HMHBALJH_00261 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HMHBALJH_00262 2.5e-175
HMHBALJH_00263 3.2e-189 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMHBALJH_00264 8.5e-151 metQ_4 P Belongs to the nlpA lipoprotein family
HMHBALJH_00268 4.7e-10
HMHBALJH_00270 5.6e-138 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HMHBALJH_00271 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMHBALJH_00272 3.7e-151 S hydrolase
HMHBALJH_00273 5.5e-261 npr 1.11.1.1 C NADH oxidase
HMHBALJH_00274 1.3e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMHBALJH_00275 1.9e-184 hrtB V ABC transporter permease
HMHBALJH_00276 1.5e-86 ygfC K Bacterial regulatory proteins, tetR family
HMHBALJH_00277 1.8e-144 yqfZ 3.2.1.17 M hydrolase, family 25
HMHBALJH_00278 1.3e-17 S YvrJ protein family
HMHBALJH_00279 6.7e-08 K DNA-templated transcription, initiation
HMHBALJH_00280 5.7e-119
HMHBALJH_00281 4.4e-57 pnb C nitroreductase
HMHBALJH_00282 1.9e-18 hxlR K Transcriptional regulator, HxlR family
HMHBALJH_00283 1.5e-272 abgB 3.5.1.47 S Peptidase dimerisation domain
HMHBALJH_00284 4.3e-209 G Major Facilitator Superfamily
HMHBALJH_00285 1.7e-193 GK helix_turn_helix, arabinose operon control protein
HMHBALJH_00286 7.3e-275 emrY EGP Major facilitator Superfamily
HMHBALJH_00287 1.1e-80 merR K MerR HTH family regulatory protein
HMHBALJH_00288 8.1e-266 lmrB EGP Major facilitator Superfamily
HMHBALJH_00289 1e-112 S Domain of unknown function (DUF4811)
HMHBALJH_00290 9.7e-118 3.6.1.27 I Acid phosphatase homologues
HMHBALJH_00291 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMHBALJH_00292 2.4e-279 ytgP S Polysaccharide biosynthesis protein
HMHBALJH_00293 1.7e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMHBALJH_00294 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HMHBALJH_00295 1.5e-139 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMHBALJH_00296 5.1e-95 FNV0100 F NUDIX domain
HMHBALJH_00298 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HMHBALJH_00299 7.4e-225 malY 4.4.1.8 E Aminotransferase, class I
HMHBALJH_00300 3.8e-222 cpdA S Calcineurin-like phosphoesterase
HMHBALJH_00301 1.5e-37 gcvR T Belongs to the UPF0237 family
HMHBALJH_00302 1.3e-243 XK27_08635 S UPF0210 protein
HMHBALJH_00303 4.1e-211 coiA 3.6.4.12 S Competence protein
HMHBALJH_00304 1.5e-115 yjbH Q Thioredoxin
HMHBALJH_00305 1.2e-103 yjbK S CYTH
HMHBALJH_00306 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HMHBALJH_00307 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMHBALJH_00308 7.8e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HMHBALJH_00309 7.7e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMHBALJH_00310 1.3e-111 cutC P Participates in the control of copper homeostasis
HMHBALJH_00311 3.5e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMHBALJH_00312 3.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMHBALJH_00313 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMHBALJH_00314 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMHBALJH_00315 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMHBALJH_00316 5.7e-172 corA P CorA-like Mg2+ transporter protein
HMHBALJH_00317 6.2e-154 rrmA 2.1.1.187 H Methyltransferase
HMHBALJH_00318 2.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMHBALJH_00319 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
HMHBALJH_00320 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMHBALJH_00321 6.1e-230 ymfF S Peptidase M16 inactive domain protein
HMHBALJH_00322 2.2e-243 ymfH S Peptidase M16
HMHBALJH_00323 1.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
HMHBALJH_00324 4.4e-116 ymfM S Helix-turn-helix domain
HMHBALJH_00325 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMHBALJH_00326 4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HMHBALJH_00327 3.3e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMHBALJH_00328 1.3e-12
HMHBALJH_00329 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
HMHBALJH_00330 2.1e-117 yvyE 3.4.13.9 S YigZ family
HMHBALJH_00331 1.4e-234 comFA L Helicase C-terminal domain protein
HMHBALJH_00332 1.3e-90 comFC S Competence protein
HMHBALJH_00333 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMHBALJH_00334 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMHBALJH_00335 1.1e-178 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMHBALJH_00336 1.9e-124 ftsE D ABC transporter
HMHBALJH_00337 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMHBALJH_00338 6.5e-196 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HMHBALJH_00339 5.2e-130 K response regulator
HMHBALJH_00340 6.4e-304 phoR 2.7.13.3 T Histidine kinase
HMHBALJH_00341 1.2e-155 pstS P Phosphate
HMHBALJH_00342 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HMHBALJH_00343 1.1e-156 pstA P Phosphate transport system permease protein PstA
HMHBALJH_00344 6.9e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMHBALJH_00345 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMHBALJH_00346 1e-119 phoU P Plays a role in the regulation of phosphate uptake
HMHBALJH_00347 5.5e-214 yvlB S Putative adhesin
HMHBALJH_00348 2.1e-31
HMHBALJH_00349 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HMHBALJH_00350 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMHBALJH_00351 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMHBALJH_00352 2e-194 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMHBALJH_00353 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMHBALJH_00354 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMHBALJH_00355 7.9e-117 yfbR S HD containing hydrolase-like enzyme
HMHBALJH_00356 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMHBALJH_00357 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMHBALJH_00358 6.7e-85 S Short repeat of unknown function (DUF308)
HMHBALJH_00359 1.3e-165 rapZ S Displays ATPase and GTPase activities
HMHBALJH_00360 1.7e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMHBALJH_00361 1.6e-171 whiA K May be required for sporulation
HMHBALJH_00362 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
HMHBALJH_00363 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMHBALJH_00365 3.6e-188 cggR K Putative sugar-binding domain
HMHBALJH_00366 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMHBALJH_00367 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMHBALJH_00368 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMHBALJH_00369 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMHBALJH_00370 5.9e-64
HMHBALJH_00371 7e-292 clcA P chloride
HMHBALJH_00372 1.7e-60
HMHBALJH_00373 9.3e-31 secG U Preprotein translocase
HMHBALJH_00374 5.4e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HMHBALJH_00375 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMHBALJH_00376 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMHBALJH_00377 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMHBALJH_00378 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMHBALJH_00379 4.2e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HMHBALJH_00380 8.7e-50
HMHBALJH_00381 4.7e-235 YSH1 S Metallo-beta-lactamase superfamily
HMHBALJH_00382 4.4e-239 malE G Bacterial extracellular solute-binding protein
HMHBALJH_00383 4.2e-147 malF G Binding-protein-dependent transport system inner membrane component
HMHBALJH_00384 2.6e-166 malG P ABC-type sugar transport systems, permease components
HMHBALJH_00385 1e-193 malK P ATPases associated with a variety of cellular activities
HMHBALJH_00386 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
HMHBALJH_00387 9e-92 yxjI
HMHBALJH_00388 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMHBALJH_00389 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMHBALJH_00390 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMHBALJH_00391 1.2e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMHBALJH_00392 1.5e-166 natA S ABC transporter, ATP-binding protein
HMHBALJH_00393 5.3e-218 ysdA CP ABC-2 family transporter protein
HMHBALJH_00394 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HMHBALJH_00395 1.6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HMHBALJH_00396 9.5e-158 murB 1.3.1.98 M Cell wall formation
HMHBALJH_00397 0.0 yjcE P Sodium proton antiporter
HMHBALJH_00398 2.9e-96 puuR K Cupin domain
HMHBALJH_00399 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMHBALJH_00400 1.7e-148 potB P ABC transporter permease
HMHBALJH_00401 8.9e-145 potC P ABC transporter permease
HMHBALJH_00402 3.6e-207 potD P ABC transporter
HMHBALJH_00403 5.2e-14 T SpoVT / AbrB like domain
HMHBALJH_00405 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HMHBALJH_00406 5.8e-118 K Transcriptional regulator
HMHBALJH_00407 2.7e-184 V ABC transporter
HMHBALJH_00408 2.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
HMHBALJH_00409 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMHBALJH_00410 7e-166 ybbR S YbbR-like protein
HMHBALJH_00411 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMHBALJH_00412 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMHBALJH_00413 0.0 pepF2 E Oligopeptidase F
HMHBALJH_00414 9.7e-91 S VanZ like family
HMHBALJH_00415 3.4e-132 yebC K Transcriptional regulatory protein
HMHBALJH_00416 1.5e-131 comGA NU Type II IV secretion system protein
HMHBALJH_00417 1.2e-164 comGB NU type II secretion system
HMHBALJH_00418 5.1e-48
HMHBALJH_00420 1.1e-47
HMHBALJH_00421 1.1e-80
HMHBALJH_00422 4.6e-49
HMHBALJH_00423 4.5e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
HMHBALJH_00424 3.3e-72
HMHBALJH_00425 3.5e-247 cycA E Amino acid permease
HMHBALJH_00426 3.8e-142 arbV 2.3.1.51 I Phosphate acyltransferases
HMHBALJH_00427 9.5e-163 arbx M Glycosyl transferase family 8
HMHBALJH_00428 1.5e-180 arbY M family 8
HMHBALJH_00429 9.1e-164 arbZ I Phosphate acyltransferases
HMHBALJH_00430 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMHBALJH_00431 1.2e-213 sip L Belongs to the 'phage' integrase family
HMHBALJH_00434 2.1e-29
HMHBALJH_00435 4.4e-17
HMHBALJH_00436 1.1e-21
HMHBALJH_00438 1.9e-23
HMHBALJH_00439 2.9e-148 L Bifunctional DNA primase/polymerase, N-terminal
HMHBALJH_00440 1.9e-300 S Phage plasmid primase, P4
HMHBALJH_00441 3.9e-51 S Phage head-tail joining protein
HMHBALJH_00443 5.1e-24 L Phage-associated protein
HMHBALJH_00444 5.3e-78 terS L Phage terminase, small subunit
HMHBALJH_00445 0.0 terL S overlaps another CDS with the same product name
HMHBALJH_00446 2.5e-20
HMHBALJH_00447 1e-218 S Phage portal protein
HMHBALJH_00448 5.5e-273 S Phage capsid family
HMHBALJH_00449 7.4e-46 S Phage gp6-like head-tail connector protein
HMHBALJH_00451 2.9e-16
HMHBALJH_00452 2.2e-14 ytgB S Transglycosylase associated protein
HMHBALJH_00454 3.8e-69 S SdpI/YhfL protein family
HMHBALJH_00455 3.1e-133 K response regulator
HMHBALJH_00456 4.6e-272 yclK 2.7.13.3 T Histidine kinase
HMHBALJH_00457 1.3e-93 yhbS S acetyltransferase
HMHBALJH_00458 7.6e-31
HMHBALJH_00459 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HMHBALJH_00460 3.8e-82
HMHBALJH_00461 5.3e-59
HMHBALJH_00462 5.5e-250 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HMHBALJH_00464 8.1e-176 S response to antibiotic
HMHBALJH_00466 9.8e-214 tnpB L Putative transposase DNA-binding domain
HMHBALJH_00467 8.3e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HMHBALJH_00468 4.5e-28 yjgN S Bacterial protein of unknown function (DUF898)
HMHBALJH_00469 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMHBALJH_00470 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMHBALJH_00471 1.2e-203 camS S sex pheromone
HMHBALJH_00472 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMHBALJH_00473 3.3e-264 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMHBALJH_00474 6.1e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMHBALJH_00475 2.9e-193 yegS 2.7.1.107 G Lipid kinase
HMHBALJH_00476 2.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMHBALJH_00477 1.2e-216 yttB EGP Major facilitator Superfamily
HMHBALJH_00478 3.9e-145 cof S Sucrose-6F-phosphate phosphohydrolase
HMHBALJH_00479 2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HMHBALJH_00480 0.0 pepO 3.4.24.71 O Peptidase family M13
HMHBALJH_00481 3.7e-76 K Acetyltransferase (GNAT) domain
HMHBALJH_00482 6.8e-164 degV S Uncharacterised protein, DegV family COG1307
HMHBALJH_00483 5e-120 qmcA O prohibitin homologues
HMHBALJH_00484 3.2e-29
HMHBALJH_00485 7.5e-132 lys M Glycosyl hydrolases family 25
HMHBALJH_00486 1.1e-59 S Protein of unknown function (DUF1093)
HMHBALJH_00487 2e-61 S Domain of unknown function (DUF4828)
HMHBALJH_00488 1.7e-177 mocA S Oxidoreductase
HMHBALJH_00489 4.5e-236 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMHBALJH_00490 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_00491 1.9e-71 S Domain of unknown function (DUF3284)
HMHBALJH_00493 5.7e-07
HMHBALJH_00494 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMHBALJH_00496 2.4e-239 pepS E Thermophilic metalloprotease (M29)
HMHBALJH_00497 2.7e-111 K Bacterial regulatory proteins, tetR family
HMHBALJH_00498 1.4e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
HMHBALJH_00499 7.3e-178 yihY S Belongs to the UPF0761 family
HMHBALJH_00500 1.9e-80 fld C Flavodoxin
HMHBALJH_00501 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
HMHBALJH_00502 5.8e-194 M Glycosyltransferase like family 2
HMHBALJH_00504 4.5e-29
HMHBALJH_00505 4.9e-125 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMHBALJH_00506 6.8e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMHBALJH_00507 8.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMHBALJH_00509 6.8e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMHBALJH_00510 0.0 S Bacterial membrane protein YfhO
HMHBALJH_00511 2.6e-308 S Psort location CytoplasmicMembrane, score
HMHBALJH_00512 1.6e-83 S Fic/DOC family
HMHBALJH_00513 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMHBALJH_00514 2.3e-108
HMHBALJH_00515 8.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
HMHBALJH_00516 2.1e-31 cspC K Cold shock protein
HMHBALJH_00517 2.5e-13 chpR T PFAM SpoVT AbrB
HMHBALJH_00518 8.1e-82 yvbK 3.1.3.25 K GNAT family
HMHBALJH_00519 2.3e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMHBALJH_00520 1.2e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMHBALJH_00521 2.1e-241 pbuX F xanthine permease
HMHBALJH_00522 1.9e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMHBALJH_00523 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMHBALJH_00524 1.2e-103
HMHBALJH_00525 8e-129
HMHBALJH_00526 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMHBALJH_00527 3.7e-108 vanZ V VanZ like family
HMHBALJH_00528 2.9e-151 glcU U sugar transport
HMHBALJH_00529 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
HMHBALJH_00530 8.8e-223 L Pfam:Integrase_AP2
HMHBALJH_00532 1.1e-178
HMHBALJH_00533 4.7e-31
HMHBALJH_00534 2e-60 S Pyridoxamine 5'-phosphate oxidase
HMHBALJH_00537 2e-66 S Domain of unknown function (DUF5067)
HMHBALJH_00538 2.9e-34
HMHBALJH_00539 1e-09 E IrrE N-terminal-like domain
HMHBALJH_00540 1.8e-24 S sequence-specific DNA binding
HMHBALJH_00541 7.8e-10 2.5.1.7 K Helix-turn-helix domain
HMHBALJH_00544 2.4e-10 S Domain of unknown function (DUF1508)
HMHBALJH_00546 5.4e-98
HMHBALJH_00548 1.6e-13
HMHBALJH_00551 4.6e-152 recT L RecT family
HMHBALJH_00552 8e-131 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HMHBALJH_00553 1.3e-134 L Replication initiation and membrane attachment
HMHBALJH_00555 6.6e-63 S Hypothetical protein (DUF2513)
HMHBALJH_00556 2e-08 K Cro/C1-type HTH DNA-binding domain
HMHBALJH_00557 2.9e-49
HMHBALJH_00558 7.6e-39
HMHBALJH_00559 3e-65 S magnesium ion binding
HMHBALJH_00560 8.5e-20
HMHBALJH_00561 1.7e-27
HMHBALJH_00562 3.3e-114 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMHBALJH_00563 7.6e-36 S Protein of unknown function (DUF1642)
HMHBALJH_00566 9.1e-77
HMHBALJH_00567 2.3e-156
HMHBALJH_00568 3.1e-239
HMHBALJH_00569 2.4e-50
HMHBALJH_00570 2.6e-18 L DNA packaging
HMHBALJH_00571 8.4e-248 S Terminase-like family
HMHBALJH_00572 9.5e-256 S Phage portal protein
HMHBALJH_00573 5.2e-176 S head morphogenesis protein, SPP1 gp7 family
HMHBALJH_00574 3.4e-75 S Domain of unknown function (DUF4355)
HMHBALJH_00575 3.1e-184 gpG
HMHBALJH_00576 2.3e-60 S Phage gp6-like head-tail connector protein
HMHBALJH_00577 2.1e-48
HMHBALJH_00578 2.3e-57 S Bacteriophage HK97-gp10, putative tail-component
HMHBALJH_00579 2.9e-69 S Protein of unknown function (DUF3168)
HMHBALJH_00580 7.2e-104 S Phage tail tube protein
HMHBALJH_00581 6.2e-49 S Phage tail assembly chaperone protein, TAC
HMHBALJH_00582 6.2e-59
HMHBALJH_00583 4.1e-280 S phage tail tape measure protein
HMHBALJH_00584 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMHBALJH_00585 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HMHBALJH_00586 1.2e-279 uxaC 5.3.1.12 G glucuronate isomerase
HMHBALJH_00587 1.7e-217 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HMHBALJH_00588 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HMHBALJH_00589 1e-266 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HMHBALJH_00590 5.6e-245 G Major Facilitator
HMHBALJH_00591 1.2e-126 kdgR K FCD domain
HMHBALJH_00592 1.5e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HMHBALJH_00593 0.0 M Glycosyl hydrolase family 59
HMHBALJH_00594 5.6e-58
HMHBALJH_00595 1e-64 S pyridoxamine 5-phosphate
HMHBALJH_00596 2.6e-242 EGP Major facilitator Superfamily
HMHBALJH_00598 0.0 ydgH S MMPL family
HMHBALJH_00599 5.9e-106 K Tetracycline repressor, C-terminal all-alpha domain
HMHBALJH_00600 9.7e-122 S Sulfite exporter TauE/SafE
HMHBALJH_00601 1.3e-246 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HMHBALJH_00602 3.3e-69 S An automated process has identified a potential problem with this gene model
HMHBALJH_00603 1e-148 S Protein of unknown function (DUF3100)
HMHBALJH_00605 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HMHBALJH_00606 7.8e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMHBALJH_00607 4.7e-106 opuCB E ABC transporter permease
HMHBALJH_00608 1.6e-214 opuCA E ABC transporter, ATP-binding protein
HMHBALJH_00609 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HMHBALJH_00610 6.2e-32 copZ P Heavy-metal-associated domain
HMHBALJH_00611 1.2e-100 dps P Belongs to the Dps family
HMHBALJH_00612 6.8e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMHBALJH_00613 1.3e-96 K Bacterial regulatory proteins, tetR family
HMHBALJH_00614 1.6e-83 S Protein of unknown function with HXXEE motif
HMHBALJH_00616 1e-159 S CAAX protease self-immunity
HMHBALJH_00618 2.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMHBALJH_00619 1.4e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMHBALJH_00620 1.1e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HMHBALJH_00621 7.3e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMHBALJH_00622 1.5e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMHBALJH_00623 2.4e-304 norB EGP Major Facilitator
HMHBALJH_00624 5.2e-110 K Bacterial regulatory proteins, tetR family
HMHBALJH_00625 3.8e-41
HMHBALJH_00626 5.1e-64
HMHBALJH_00628 6.8e-107 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
HMHBALJH_00629 2.8e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMHBALJH_00630 3.5e-163 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMHBALJH_00631 1.9e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMHBALJH_00632 1.5e-68 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMHBALJH_00633 6.2e-257 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMHBALJH_00634 6.4e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMHBALJH_00635 9e-184 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMHBALJH_00636 5.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMHBALJH_00637 6.6e-63
HMHBALJH_00638 1.2e-49 K sequence-specific DNA binding
HMHBALJH_00639 2.5e-71 3.6.1.55 L NUDIX domain
HMHBALJH_00640 1.5e-150 EG EamA-like transporter family
HMHBALJH_00642 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMHBALJH_00643 5.1e-70 rplI J Binds to the 23S rRNA
HMHBALJH_00644 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMHBALJH_00645 4e-220
HMHBALJH_00646 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMHBALJH_00647 2.2e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMHBALJH_00648 2.3e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HMHBALJH_00649 1.8e-156 K Helix-turn-helix domain, rpiR family
HMHBALJH_00650 9.1e-107 K Transcriptional regulator C-terminal region
HMHBALJH_00651 5.4e-127 V ABC transporter, ATP-binding protein
HMHBALJH_00652 0.0 ylbB V ABC transporter permease
HMHBALJH_00653 2.5e-205 4.1.1.52 S Amidohydrolase
HMHBALJH_00654 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMHBALJH_00655 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HMHBALJH_00656 6e-55 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HMHBALJH_00657 9.1e-153 K Helix-turn-helix XRE-family like proteins
HMHBALJH_00658 9.7e-27 S Phospholipase_D-nuclease N-terminal
HMHBALJH_00659 3.4e-121 yxlF V ABC transporter
HMHBALJH_00660 2e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMHBALJH_00661 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMHBALJH_00662 1e-122
HMHBALJH_00663 1.4e-181 yveB 2.7.4.29 I PAP2 superfamily
HMHBALJH_00664 1.8e-206 mccF V LD-carboxypeptidase
HMHBALJH_00666 2.5e-42
HMHBALJH_00667 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMHBALJH_00668 1.1e-40
HMHBALJH_00669 8.5e-111
HMHBALJH_00670 1.5e-224 EGP Major facilitator Superfamily
HMHBALJH_00671 5.7e-86
HMHBALJH_00672 2.9e-201 T PhoQ Sensor
HMHBALJH_00673 1.6e-120 K Transcriptional regulatory protein, C terminal
HMHBALJH_00674 8.2e-90 ogt 2.1.1.63 L Methyltransferase
HMHBALJH_00675 1.2e-191 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMHBALJH_00676 4.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_00677 1.3e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_00678 8e-85
HMHBALJH_00679 7.2e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_00680 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_00681 5.8e-132 K UTRA
HMHBALJH_00682 6.1e-40
HMHBALJH_00683 4e-57 ypaA S Protein of unknown function (DUF1304)
HMHBALJH_00684 1.2e-53 S Protein of unknown function (DUF1516)
HMHBALJH_00685 1.4e-254 pbuO S permease
HMHBALJH_00686 3.4e-52 S DsrE/DsrF-like family
HMHBALJH_00687 4.9e-187 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMHBALJH_00688 4.5e-43
HMHBALJH_00689 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMHBALJH_00690 0.0
HMHBALJH_00692 4.1e-123 yqcC S WxL domain surface cell wall-binding
HMHBALJH_00693 6.2e-183 ynjC S Cell surface protein
HMHBALJH_00694 9.2e-270 L Mga helix-turn-helix domain
HMHBALJH_00695 7e-149 yhaI S Protein of unknown function (DUF805)
HMHBALJH_00696 9.4e-58
HMHBALJH_00697 1.6e-252 rarA L recombination factor protein RarA
HMHBALJH_00698 6.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMHBALJH_00699 3.2e-133 K DeoR C terminal sensor domain
HMHBALJH_00700 6e-285 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HMHBALJH_00701 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HMHBALJH_00702 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
HMHBALJH_00703 2.2e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HMHBALJH_00704 7.7e-137 magIII L Base excision DNA repair protein, HhH-GPD family
HMHBALJH_00705 5.7e-248 bmr3 EGP Major facilitator Superfamily
HMHBALJH_00708 1.7e-89
HMHBALJH_00710 8.6e-47 V ATPase activity
HMHBALJH_00711 6.3e-15
HMHBALJH_00713 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMHBALJH_00714 1.8e-303 oppA E ABC transporter, substratebinding protein
HMHBALJH_00715 2.2e-76
HMHBALJH_00716 8.6e-117
HMHBALJH_00717 9.3e-122
HMHBALJH_00718 2.5e-118 V ATPases associated with a variety of cellular activities
HMHBALJH_00719 1.6e-74
HMHBALJH_00720 3e-81 S NUDIX domain
HMHBALJH_00721 2.3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
HMHBALJH_00722 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HMHBALJH_00723 4.7e-260 nox 1.6.3.4 C NADH oxidase
HMHBALJH_00724 1.7e-116
HMHBALJH_00725 1.6e-233 S TPM domain
HMHBALJH_00726 4e-129 yxaA S Sulfite exporter TauE/SafE
HMHBALJH_00727 1e-55 ywjH S Protein of unknown function (DUF1634)
HMHBALJH_00729 6.5e-65
HMHBALJH_00730 1.6e-51
HMHBALJH_00731 1.9e-83 fld C Flavodoxin
HMHBALJH_00732 3.4e-36
HMHBALJH_00733 6.7e-27
HMHBALJH_00734 4.4e-172 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMHBALJH_00735 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HMHBALJH_00736 6.4e-38 S Transglycosylase associated protein
HMHBALJH_00737 1.5e-89 S Protein conserved in bacteria
HMHBALJH_00738 2.5e-29
HMHBALJH_00739 5.1e-61 asp23 S Asp23 family, cell envelope-related function
HMHBALJH_00740 7.9e-65 asp2 S Asp23 family, cell envelope-related function
HMHBALJH_00741 1.8e-129 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMHBALJH_00742 1.7e-114 S Protein of unknown function (DUF969)
HMHBALJH_00743 6.7e-146 S Protein of unknown function (DUF979)
HMHBALJH_00744 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMHBALJH_00745 2.1e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HMHBALJH_00747 1e-127 cobQ S glutamine amidotransferase
HMHBALJH_00748 2.2e-66
HMHBALJH_00749 2.3e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMHBALJH_00750 2.4e-142 noc K Belongs to the ParB family
HMHBALJH_00751 2.5e-138 soj D Sporulation initiation inhibitor
HMHBALJH_00752 2e-155 spo0J K Belongs to the ParB family
HMHBALJH_00753 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HMHBALJH_00754 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMHBALJH_00755 1.6e-140 XK27_01040 S Protein of unknown function (DUF1129)
HMHBALJH_00756 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMHBALJH_00757 1.5e-118
HMHBALJH_00758 2.5e-121 K response regulator
HMHBALJH_00759 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
HMHBALJH_00760 1.4e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMHBALJH_00761 3.6e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMHBALJH_00762 2.7e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMHBALJH_00763 5.4e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HMHBALJH_00764 4.4e-163 yvgN C Aldo keto reductase
HMHBALJH_00765 1.6e-140 iolR K DeoR C terminal sensor domain
HMHBALJH_00766 1.5e-267 iolT EGP Major facilitator Superfamily
HMHBALJH_00767 9.5e-275 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
HMHBALJH_00768 8.4e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HMHBALJH_00769 1.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HMHBALJH_00770 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HMHBALJH_00771 3.2e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HMHBALJH_00772 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HMHBALJH_00773 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HMHBALJH_00774 9.6e-158 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
HMHBALJH_00775 1.1e-65 iolK S Tautomerase enzyme
HMHBALJH_00776 3.9e-131 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
HMHBALJH_00777 1.3e-170 iolH G Xylose isomerase-like TIM barrel
HMHBALJH_00778 2.1e-146 gntR K rpiR family
HMHBALJH_00779 4.4e-167 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HMHBALJH_00780 1.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HMHBALJH_00781 2.8e-204 gntP EG Gluconate
HMHBALJH_00782 7.6e-58
HMHBALJH_00783 4.1e-130 fhuC 3.6.3.35 P ABC transporter
HMHBALJH_00784 3e-134 znuB U ABC 3 transport family
HMHBALJH_00785 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HMHBALJH_00786 1.9e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HMHBALJH_00787 0.0 pepF E oligoendopeptidase F
HMHBALJH_00788 5.7e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMHBALJH_00789 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
HMHBALJH_00790 1.1e-71 T Sh3 type 3 domain protein
HMHBALJH_00791 1.5e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMHBALJH_00792 2.2e-134 glcR K DeoR C terminal sensor domain
HMHBALJH_00793 2.6e-146 M Glycosyltransferase like family 2
HMHBALJH_00794 1.8e-133 XK27_06755 S Protein of unknown function (DUF975)
HMHBALJH_00795 2.2e-52
HMHBALJH_00796 1.8e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMHBALJH_00797 2.1e-174 draG O ADP-ribosylglycohydrolase
HMHBALJH_00798 8.9e-292 S ABC transporter
HMHBALJH_00799 2e-135 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
HMHBALJH_00800 4.4e-101 S ECF transporter, substrate-specific component
HMHBALJH_00801 1.7e-210 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMHBALJH_00802 4.1e-158 5.1.3.3 G Aldose 1-epimerase
HMHBALJH_00803 1.8e-101 V Restriction endonuclease
HMHBALJH_00804 8.8e-161 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HMHBALJH_00805 2.4e-47
HMHBALJH_00806 5e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HMHBALJH_00807 1.4e-210 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HMHBALJH_00808 2.5e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMHBALJH_00809 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMHBALJH_00810 1.3e-79 F Nucleoside 2-deoxyribosyltransferase
HMHBALJH_00811 9.4e-253 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMHBALJH_00812 6e-64
HMHBALJH_00813 5.2e-292 frvR K Mga helix-turn-helix domain
HMHBALJH_00814 4.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMHBALJH_00815 1.4e-104 ygaC J Belongs to the UPF0374 family
HMHBALJH_00816 2.8e-96
HMHBALJH_00817 3.3e-74 S Acetyltransferase (GNAT) domain
HMHBALJH_00818 6.8e-207 yueF S AI-2E family transporter
HMHBALJH_00819 8.7e-243 hlyX S Transporter associated domain
HMHBALJH_00820 2.3e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMHBALJH_00821 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
HMHBALJH_00822 0.0 clpE O Belongs to the ClpA ClpB family
HMHBALJH_00823 2e-28
HMHBALJH_00824 1.4e-38 ptsH G phosphocarrier protein HPR
HMHBALJH_00825 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMHBALJH_00826 1.2e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMHBALJH_00827 1.8e-254 iolT EGP Major facilitator Superfamily
HMHBALJH_00829 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
HMHBALJH_00830 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMHBALJH_00831 5.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMHBALJH_00832 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMHBALJH_00833 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMHBALJH_00834 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMHBALJH_00835 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMHBALJH_00836 9e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMHBALJH_00837 1.6e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMHBALJH_00838 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMHBALJH_00839 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMHBALJH_00840 2e-217 purD 6.3.4.13 F Belongs to the GARS family
HMHBALJH_00841 1.6e-76 copR K Copper transport repressor CopY TcrY
HMHBALJH_00842 0.0 copB 3.6.3.4 P P-type ATPase
HMHBALJH_00843 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMHBALJH_00844 1.3e-207 T PhoQ Sensor
HMHBALJH_00845 1e-122 K response regulator
HMHBALJH_00846 1.3e-137 bceA V ABC transporter
HMHBALJH_00847 0.0 V ABC transporter (permease)
HMHBALJH_00848 2.9e-90 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
HMHBALJH_00849 1.2e-137 yhfI S Metallo-beta-lactamase superfamily
HMHBALJH_00850 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMHBALJH_00851 2.5e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMHBALJH_00852 1.2e-303 glpQ 3.1.4.46 C phosphodiesterase
HMHBALJH_00853 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HMHBALJH_00854 1.5e-20
HMHBALJH_00855 1.2e-67
HMHBALJH_00857 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMHBALJH_00858 5.3e-75 argR K Regulates arginine biosynthesis genes
HMHBALJH_00859 1.1e-65 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMHBALJH_00860 9.4e-68 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMHBALJH_00861 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMHBALJH_00862 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
HMHBALJH_00863 9.6e-183 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMHBALJH_00864 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMHBALJH_00865 4.8e-47 yhaH S YtxH-like protein
HMHBALJH_00866 1.1e-74 hit FG histidine triad
HMHBALJH_00867 2.2e-131 ecsA V ABC transporter, ATP-binding protein
HMHBALJH_00868 2.8e-224 ecsB U ABC transporter
HMHBALJH_00869 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HMHBALJH_00870 2.9e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMHBALJH_00872 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMHBALJH_00873 9.9e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMHBALJH_00875 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HMHBALJH_00876 2.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMHBALJH_00877 5.9e-264 K Mga helix-turn-helix domain
HMHBALJH_00878 0.0 N domain, Protein
HMHBALJH_00879 8.4e-137 S WxL domain surface cell wall-binding
HMHBALJH_00881 2.3e-190 S Cell surface protein
HMHBALJH_00883 2.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
HMHBALJH_00884 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMHBALJH_00885 5.5e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMHBALJH_00886 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMHBALJH_00887 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMHBALJH_00888 5.1e-251 dnaB L replication initiation and membrane attachment
HMHBALJH_00889 1.2e-169 dnaI L Primosomal protein DnaI
HMHBALJH_00890 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMHBALJH_00891 7.2e-61 yrgI 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HMHBALJH_00892 3.6e-64
HMHBALJH_00893 2.4e-127 S SseB protein N-terminal domain
HMHBALJH_00894 1.7e-136 cobB K Sir2 family
HMHBALJH_00895 3.1e-232 EGP Major Facilitator Superfamily
HMHBALJH_00896 9e-72 K Transcriptional regulator
HMHBALJH_00897 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMHBALJH_00898 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMHBALJH_00899 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMHBALJH_00900 1.5e-100 yvdD 3.2.2.10 S Belongs to the LOG family
HMHBALJH_00901 4.4e-180 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HMHBALJH_00902 1.8e-121 mhqD S Dienelactone hydrolase family
HMHBALJH_00903 7.3e-191 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMHBALJH_00904 8.9e-167 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMHBALJH_00905 2.4e-95 yqeG S HAD phosphatase, family IIIA
HMHBALJH_00906 3.4e-216 yqeH S Ribosome biogenesis GTPase YqeH
HMHBALJH_00907 1.1e-47 yhbY J RNA-binding protein
HMHBALJH_00908 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMHBALJH_00909 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMHBALJH_00910 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMHBALJH_00911 1.9e-138 yqeM Q Methyltransferase
HMHBALJH_00912 1e-207 ylbM S Belongs to the UPF0348 family
HMHBALJH_00913 7.7e-97 yceD S Uncharacterized ACR, COG1399
HMHBALJH_00915 7.1e-18 yhcX S Psort location Cytoplasmic, score
HMHBALJH_00916 2.2e-58 L Probable transposase
HMHBALJH_00917 4e-164 L Probable transposase
HMHBALJH_00918 5.6e-140 M Peptidase family M23
HMHBALJH_00919 1.6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMHBALJH_00920 7.9e-123 K response regulator
HMHBALJH_00921 3.6e-288 arlS 2.7.13.3 T Histidine kinase
HMHBALJH_00922 3.8e-179 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMHBALJH_00923 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMHBALJH_00924 2.1e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMHBALJH_00925 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMHBALJH_00926 6.9e-68 yodB K Transcriptional regulator, HxlR family
HMHBALJH_00927 6.4e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMHBALJH_00928 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMHBALJH_00929 1.1e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMHBALJH_00930 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HMHBALJH_00931 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMHBALJH_00932 2.3e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HMHBALJH_00933 2.3e-182 vraS 2.7.13.3 T Histidine kinase
HMHBALJH_00934 5.8e-115 vraR K helix_turn_helix, Lux Regulon
HMHBALJH_00935 2.9e-53 yneR S Belongs to the HesB IscA family
HMHBALJH_00936 0.0 S Bacterial membrane protein YfhO
HMHBALJH_00937 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMHBALJH_00938 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
HMHBALJH_00939 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
HMHBALJH_00940 2e-177 glk 2.7.1.2 G Glucokinase
HMHBALJH_00941 3.7e-72 yqhL P Rhodanese-like protein
HMHBALJH_00942 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
HMHBALJH_00943 5.7e-180 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMHBALJH_00944 5.9e-241 ynbB 4.4.1.1 P aluminum resistance
HMHBALJH_00945 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HMHBALJH_00946 5e-60 glnR K Transcriptional regulator
HMHBALJH_00947 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
HMHBALJH_00948 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMHBALJH_00949 6.4e-264 V ABC transporter transmembrane region
HMHBALJH_00951 7.4e-233 ywhK S Membrane
HMHBALJH_00952 4.1e-14
HMHBALJH_00953 1.3e-32
HMHBALJH_00954 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMHBALJH_00955 1e-54 ysxB J Cysteine protease Prp
HMHBALJH_00956 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMHBALJH_00957 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMHBALJH_00958 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMHBALJH_00959 1.5e-72 yqhY S Asp23 family, cell envelope-related function
HMHBALJH_00960 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMHBALJH_00961 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMHBALJH_00962 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMHBALJH_00963 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMHBALJH_00964 9.7e-147 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMHBALJH_00965 3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMHBALJH_00966 2e-74 argR K Regulates arginine biosynthesis genes
HMHBALJH_00967 1.7e-307 recN L May be involved in recombinational repair of damaged DNA
HMHBALJH_00968 3e-50
HMHBALJH_00969 1.6e-120 rssA S Patatin-like phospholipase
HMHBALJH_00970 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMHBALJH_00971 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMHBALJH_00972 8.1e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMHBALJH_00973 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMHBALJH_00974 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMHBALJH_00975 8.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMHBALJH_00976 2e-135 stp 3.1.3.16 T phosphatase
HMHBALJH_00977 0.0 KLT serine threonine protein kinase
HMHBALJH_00978 4.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMHBALJH_00979 1.5e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMHBALJH_00980 3.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMHBALJH_00981 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMHBALJH_00982 2.3e-57 asp S Asp23 family, cell envelope-related function
HMHBALJH_00983 4.7e-286 yloV S DAK2 domain fusion protein YloV
HMHBALJH_00984 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMHBALJH_00985 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMHBALJH_00986 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMHBALJH_00987 4.4e-194 oppD P Belongs to the ABC transporter superfamily
HMHBALJH_00988 1.4e-178 oppF P Belongs to the ABC transporter superfamily
HMHBALJH_00989 2.8e-174 oppB P ABC transporter permease
HMHBALJH_00990 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
HMHBALJH_00991 0.0 oppA1 E ABC transporter substrate-binding protein
HMHBALJH_00992 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMHBALJH_00993 0.0 smc D Required for chromosome condensation and partitioning
HMHBALJH_00994 9.8e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMHBALJH_00995 8.8e-53
HMHBALJH_00996 1.8e-24
HMHBALJH_00997 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMHBALJH_00998 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMHBALJH_00999 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMHBALJH_01000 8.4e-38 ylqC S Belongs to the UPF0109 family
HMHBALJH_01001 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMHBALJH_01002 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMHBALJH_01003 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMHBALJH_01004 1.1e-25
HMHBALJH_01005 1.1e-37 ynzC S UPF0291 protein
HMHBALJH_01006 4.8e-29 yneF S UPF0154 protein
HMHBALJH_01007 0.0 mdlA V ABC transporter
HMHBALJH_01008 0.0 mdlB V ABC transporter
HMHBALJH_01009 2.9e-137 yejC S Protein of unknown function (DUF1003)
HMHBALJH_01010 6.6e-201 bcaP E Amino Acid
HMHBALJH_01011 2.2e-122 plsC 2.3.1.51 I Acyltransferase
HMHBALJH_01012 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
HMHBALJH_01013 4.9e-47 yazA L GIY-YIG catalytic domain protein
HMHBALJH_01014 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HMHBALJH_01015 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMHBALJH_01016 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMHBALJH_01017 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMHBALJH_01018 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HMHBALJH_01019 9.7e-106 S Domain of unknown function (DUF1788)
HMHBALJH_01020 1.4e-104 S Putative inner membrane protein (DUF1819)
HMHBALJH_01021 1e-210 ykiI
HMHBALJH_01022 0.0 pip V domain protein
HMHBALJH_01023 0.0 scrA 2.7.1.211 G phosphotransferase system
HMHBALJH_01024 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HMHBALJH_01025 3.6e-177 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HMHBALJH_01026 8.5e-300 scrB 3.2.1.26 GH32 G invertase
HMHBALJH_01028 5.6e-158 azoB GM NmrA-like family
HMHBALJH_01029 2.3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMHBALJH_01030 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMHBALJH_01031 1e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMHBALJH_01032 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMHBALJH_01033 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMHBALJH_01034 2.3e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMHBALJH_01035 6.3e-224 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMHBALJH_01036 7.3e-127 IQ reductase
HMHBALJH_01037 2.7e-166 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMHBALJH_01038 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
HMHBALJH_01039 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMHBALJH_01040 1.6e-174 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMHBALJH_01041 2.1e-76 marR K Winged helix DNA-binding domain
HMHBALJH_01042 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMHBALJH_01043 1.9e-191 I carboxylic ester hydrolase activity
HMHBALJH_01044 4.9e-229 bdhA C Iron-containing alcohol dehydrogenase
HMHBALJH_01045 4.9e-63 P Rhodanese-like domain
HMHBALJH_01046 3.1e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
HMHBALJH_01047 4.3e-26
HMHBALJH_01048 1.3e-67 K MarR family
HMHBALJH_01049 4.1e-11 S response to antibiotic
HMHBALJH_01050 6.7e-171 S Putative esterase
HMHBALJH_01051 1e-185
HMHBALJH_01052 1.1e-104 rmaB K Transcriptional regulator, MarR family
HMHBALJH_01053 6.2e-87 F NUDIX domain
HMHBALJH_01054 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMHBALJH_01055 3.4e-29
HMHBALJH_01056 2.8e-127 S zinc-ribbon domain
HMHBALJH_01057 9.4e-203 pbpX1 V Beta-lactamase
HMHBALJH_01058 1.5e-181 K AI-2E family transporter
HMHBALJH_01059 1.1e-127 srtA 3.4.22.70 M Sortase family
HMHBALJH_01060 1.5e-65 gtcA S Teichoic acid glycosylation protein
HMHBALJH_01061 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMHBALJH_01062 1.5e-169 gbuC E glycine betaine
HMHBALJH_01063 9.4e-126 proW E glycine betaine
HMHBALJH_01064 1e-221 gbuA 3.6.3.32 E glycine betaine
HMHBALJH_01065 1.1e-135 sfsA S Belongs to the SfsA family
HMHBALJH_01066 1.1e-67 usp1 T Universal stress protein family
HMHBALJH_01067 1.6e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
HMHBALJH_01068 1.3e-159 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMHBALJH_01069 2.5e-286 thrC 4.2.3.1 E Threonine synthase
HMHBALJH_01070 4e-231 hom 1.1.1.3 E homoserine dehydrogenase
HMHBALJH_01071 1.9e-253 yclM 2.7.2.4 E Belongs to the aspartokinase family
HMHBALJH_01072 4.7e-168 yqiK S SPFH domain / Band 7 family
HMHBALJH_01073 1.5e-68
HMHBALJH_01074 1.7e-153 pfoS S Phosphotransferase system, EIIC
HMHBALJH_01075 1.4e-181 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMHBALJH_01076 2.2e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMHBALJH_01077 7.3e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
HMHBALJH_01078 6.1e-08 K Bacterial regulatory proteins, tetR family
HMHBALJH_01079 3.3e-101 K Bacterial regulatory proteins, tetR family
HMHBALJH_01080 7.3e-174 XK27_06930 V domain protein
HMHBALJH_01081 2e-169 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMHBALJH_01082 7.8e-190 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01083 2.7e-55 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01084 1.2e-175 G PTS system sugar-specific permease component
HMHBALJH_01085 3e-31 2.7.1.200 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HMHBALJH_01086 2.7e-67 S Uncharacterised protein family UPF0047
HMHBALJH_01087 8.6e-57 kdsD 5.3.1.13 M SIS domain
HMHBALJH_01088 1.9e-84 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMHBALJH_01089 4e-45 5.3.1.27 M arabinose-5-phosphate isomerase activity
HMHBALJH_01090 0.0 asnB 6.3.5.4 E Asparagine synthase
HMHBALJH_01091 3.3e-205 S Calcineurin-like phosphoesterase
HMHBALJH_01092 8.8e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMHBALJH_01093 3.9e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMHBALJH_01094 4.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMHBALJH_01095 4.8e-165 natA S ABC transporter
HMHBALJH_01096 4.5e-117 ysdA CP ABC-2 family transporter protein
HMHBALJH_01097 1.2e-71 ysdA CP ABC-2 family transporter protein
HMHBALJH_01098 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
HMHBALJH_01099 1.8e-161 CcmA V ABC transporter
HMHBALJH_01100 5.7e-115 VPA0052 I ABC-2 family transporter protein
HMHBALJH_01101 9.9e-146 IQ reductase
HMHBALJH_01102 1.5e-256 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_01103 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMHBALJH_01105 3.3e-158 licT K CAT RNA binding domain
HMHBALJH_01106 8.8e-290 cydC V ABC transporter transmembrane region
HMHBALJH_01107 1.7e-307 cydD CO ABC transporter transmembrane region
HMHBALJH_01108 1.7e-75 ynhH S NusG domain II
HMHBALJH_01109 2e-173 M Peptidoglycan-binding domain 1 protein
HMHBALJH_01110 1.3e-35 XK27_02675 K Acetyltransferase (GNAT) domain
HMHBALJH_01111 4.6e-115 S CRISPR-associated protein (Cas_Csn2)
HMHBALJH_01112 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMHBALJH_01113 6.2e-168 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMHBALJH_01114 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMHBALJH_01115 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMHBALJH_01116 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMHBALJH_01117 5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMHBALJH_01118 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HMHBALJH_01119 4.5e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HMHBALJH_01120 1.9e-173 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMHBALJH_01121 4.6e-38
HMHBALJH_01122 5.5e-86
HMHBALJH_01123 2.7e-24
HMHBALJH_01124 3.3e-161 yicL EG EamA-like transporter family
HMHBALJH_01125 2.5e-112 tag 3.2.2.20 L glycosylase
HMHBALJH_01126 4.7e-64 K Helix-turn-helix XRE-family like proteins
HMHBALJH_01127 4.2e-77 usp5 T universal stress protein
HMHBALJH_01128 3.8e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMHBALJH_01129 4.2e-222 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HMHBALJH_01130 4.1e-62
HMHBALJH_01131 1.4e-87 bioY S BioY family
HMHBALJH_01133 9.2e-102 Q methyltransferase
HMHBALJH_01134 1.9e-101 T Sh3 type 3 domain protein
HMHBALJH_01135 1.3e-113 yfeJ 6.3.5.2 F glutamine amidotransferase
HMHBALJH_01136 1.8e-136 S Uncharacterized protein conserved in bacteria (DUF2263)
HMHBALJH_01137 4.9e-257 yhdP S Transporter associated domain
HMHBALJH_01138 1.9e-144 S Alpha beta hydrolase
HMHBALJH_01139 3e-195 I Acyltransferase
HMHBALJH_01140 7.7e-261 lmrB EGP Major facilitator Superfamily
HMHBALJH_01141 2.6e-83 S Domain of unknown function (DUF4811)
HMHBALJH_01142 1.7e-96 maf D nucleoside-triphosphate diphosphatase activity
HMHBALJH_01143 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMHBALJH_01144 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMHBALJH_01145 0.0 ydaO E amino acid
HMHBALJH_01146 1.1e-56 S Domain of unknown function (DUF1827)
HMHBALJH_01147 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMHBALJH_01148 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMHBALJH_01149 2.1e-109 ydiL S CAAX protease self-immunity
HMHBALJH_01150 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMHBALJH_01152 2.1e-183
HMHBALJH_01153 3e-159 ytrB V ABC transporter
HMHBALJH_01154 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HMHBALJH_01155 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMHBALJH_01156 0.0 uup S ABC transporter, ATP-binding protein
HMHBALJH_01157 3.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01158 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMHBALJH_01159 1.8e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMHBALJH_01160 3.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMHBALJH_01161 1.9e-124
HMHBALJH_01162 4.8e-11
HMHBALJH_01163 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HMHBALJH_01164 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HMHBALJH_01165 1.1e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HMHBALJH_01166 7e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMHBALJH_01167 1.7e-57 yabA L Involved in initiation control of chromosome replication
HMHBALJH_01168 6.3e-174 holB 2.7.7.7 L DNA polymerase III
HMHBALJH_01169 7.8e-52 yaaQ S Cyclic-di-AMP receptor
HMHBALJH_01170 6.3e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMHBALJH_01171 8.7e-38 S Protein of unknown function (DUF2508)
HMHBALJH_01172 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMHBALJH_01173 3.4e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMHBALJH_01174 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMHBALJH_01175 1.3e-85 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMHBALJH_01176 1.2e-49
HMHBALJH_01177 1.5e-106 rsmC 2.1.1.172 J Methyltransferase
HMHBALJH_01178 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMHBALJH_01179 1.8e-66
HMHBALJH_01180 7.3e-172 ccpB 5.1.1.1 K lacI family
HMHBALJH_01181 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HMHBALJH_01182 1.7e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMHBALJH_01183 2.5e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMHBALJH_01184 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMHBALJH_01185 9.8e-225 mdtG EGP Major facilitator Superfamily
HMHBALJH_01186 2.9e-156 K acetyltransferase
HMHBALJH_01187 3.1e-90
HMHBALJH_01188 7.7e-222 yceI G Sugar (and other) transporter
HMHBALJH_01189 6.3e-25
HMHBALJH_01190 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01191 3.7e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HMHBALJH_01192 1.1e-130 rpl K Helix-turn-helix domain, rpiR family
HMHBALJH_01193 1.8e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMHBALJH_01194 2.3e-136 K UTRA domain
HMHBALJH_01195 1.4e-253 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
HMHBALJH_01196 3.3e-161 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01197 8.6e-129 G PTS system sorbose-specific iic component
HMHBALJH_01198 5.9e-149 G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01199 3.4e-63 K Transcriptional regulator
HMHBALJH_01200 6e-247 ypiB EGP Major facilitator Superfamily
HMHBALJH_01201 6.1e-87
HMHBALJH_01202 5e-223 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
HMHBALJH_01203 5.1e-246 G PTS system sugar-specific permease component
HMHBALJH_01204 3.6e-45 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01205 5.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01206 1.2e-109 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMHBALJH_01207 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01208 2.3e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_01209 2.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01210 5.3e-294 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_01211 6.1e-160 ypbG 2.7.1.2 GK ROK family
HMHBALJH_01212 1.2e-249 S Metal-independent alpha-mannosidase (GH125)
HMHBALJH_01213 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HMHBALJH_01214 8.1e-233 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_01215 5e-136 K UbiC transcription regulator-associated domain protein
HMHBALJH_01216 1.1e-133 fcsR K DeoR C terminal sensor domain
HMHBALJH_01217 1.7e-145 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HMHBALJH_01218 1.6e-76 fucU 5.1.3.29 G RbsD / FucU transport protein family
HMHBALJH_01219 1.5e-231 ywtG EGP Major facilitator Superfamily
HMHBALJH_01220 1.9e-294 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
HMHBALJH_01221 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
HMHBALJH_01222 2e-166 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMHBALJH_01223 1.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HMHBALJH_01224 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HMHBALJH_01225 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMHBALJH_01226 5.7e-88 iolF EGP Major facilitator Superfamily
HMHBALJH_01227 1.4e-122 iolF EGP Major facilitator Superfamily
HMHBALJH_01228 1.4e-192 rhaR K helix_turn_helix, arabinose operon control protein
HMHBALJH_01229 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HMHBALJH_01230 4.6e-64 S Protein of unknown function (DUF1093)
HMHBALJH_01231 9.5e-95
HMHBALJH_01232 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HMHBALJH_01233 1.1e-306 plyA3 M Right handed beta helix region
HMHBALJH_01234 5e-81
HMHBALJH_01235 1.6e-269 M Heparinase II/III N-terminus
HMHBALJH_01237 6e-66 G PTS system fructose IIA component
HMHBALJH_01238 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01239 6.4e-132 G PTS system sorbose-specific iic component
HMHBALJH_01240 5.4e-81 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01241 7e-204 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
HMHBALJH_01242 5.4e-102 Z012_03480 S Psort location Cytoplasmic, score
HMHBALJH_01243 1.6e-108 K Bacterial transcriptional regulator
HMHBALJH_01244 4.5e-144 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMHBALJH_01245 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMHBALJH_01246 3e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMHBALJH_01247 3.5e-151 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HMHBALJH_01248 5.1e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMHBALJH_01249 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HMHBALJH_01250 9.1e-77 rafA 3.2.1.22 G Melibiase
HMHBALJH_01251 2.2e-98 rafA 3.2.1.22 G Melibiase
HMHBALJH_01252 7.8e-40 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01253 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01254 4.4e-64 G PTS system sorbose-specific iic component
HMHBALJH_01255 2.1e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HMHBALJH_01257 4.6e-53 araR K Transcriptional regulator
HMHBALJH_01258 1.6e-271 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HMHBALJH_01259 6.9e-295 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HMHBALJH_01260 1.5e-209 V ABC-type multidrug transport system, ATPase and permease components
HMHBALJH_01261 1.1e-108 K Transcriptional activator, Rgg GadR MutR family
HMHBALJH_01262 3.3e-86 K Helix-turn-helix domain, rpiR family
HMHBALJH_01263 1.5e-10 K Helix-turn-helix domain, rpiR family
HMHBALJH_01264 2.1e-82 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMHBALJH_01266 1.8e-136 4.1.2.14 S KDGP aldolase
HMHBALJH_01267 4.2e-203 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HMHBALJH_01268 4.4e-216 dho 3.5.2.3 S Amidohydrolase family
HMHBALJH_01269 1e-106 S Domain of unknown function (DUF4310)
HMHBALJH_01270 8.3e-137 S Domain of unknown function (DUF4311)
HMHBALJH_01271 6e-53 S Domain of unknown function (DUF4312)
HMHBALJH_01272 3.4e-61 S Glycine-rich SFCGS
HMHBALJH_01273 2.4e-54 S PRD domain
HMHBALJH_01274 0.0 K Mga helix-turn-helix domain
HMHBALJH_01275 1.3e-122 tal 2.2.1.2 H Pfam:Transaldolase
HMHBALJH_01276 6.7e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMHBALJH_01277 3.6e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HMHBALJH_01278 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
HMHBALJH_01279 1.8e-87 gutM K Glucitol operon activator protein (GutM)
HMHBALJH_01280 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HMHBALJH_01281 2.2e-145 IQ NAD dependent epimerase/dehydratase family
HMHBALJH_01282 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMHBALJH_01283 4.1e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HMHBALJH_01284 3.6e-168 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HMHBALJH_01285 2.2e-137 repA K DeoR C terminal sensor domain
HMHBALJH_01286 7.4e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HMHBALJH_01287 3.7e-45 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01288 5.3e-281 ulaA S PTS system sugar-specific permease component
HMHBALJH_01289 1.1e-80 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01290 3.4e-213 ulaG S Beta-lactamase superfamily domain
HMHBALJH_01291 0.0 O Belongs to the peptidase S8 family
HMHBALJH_01292 4.5e-42
HMHBALJH_01293 6.6e-154 bglK_1 GK ROK family
HMHBALJH_01294 1.7e-179 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HMHBALJH_01295 9.1e-253 3.5.1.18 E Peptidase family M20/M25/M40
HMHBALJH_01296 3.5e-129 ymfC K UTRA
HMHBALJH_01297 5.3e-215 uhpT EGP Major facilitator Superfamily
HMHBALJH_01298 1.7e-206 3.2.1.51 GH29 G Alpha-L-fucosidase
HMHBALJH_01299 1.9e-95 S Domain of unknown function (DUF4428)
HMHBALJH_01300 2.2e-287 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HMHBALJH_01301 1.2e-204 C Zinc-binding dehydrogenase
HMHBALJH_01302 1.3e-151 manZ G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01303 3.7e-137 G PTS system sorbose-specific iic component
HMHBALJH_01304 8.5e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01305 2.3e-69 ahaA 2.7.1.191 G PTS system fructose IIA component
HMHBALJH_01306 2.6e-245 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01307 3.7e-162 G Fructose-bisphosphate aldolase class-II
HMHBALJH_01308 5.7e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HMHBALJH_01309 4.7e-252 gatC G PTS system sugar-specific permease component
HMHBALJH_01310 1.6e-48 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01311 4.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01312 6.9e-161 gatY G Fructose-bisphosphate aldolase class-II
HMHBALJH_01313 2.4e-133 farR K Helix-turn-helix domain
HMHBALJH_01314 2e-91 yjgM K Acetyltransferase (GNAT) domain
HMHBALJH_01315 3.4e-112 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HMHBALJH_01317 5.2e-96 K Helix-turn-helix domain
HMHBALJH_01318 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HMHBALJH_01319 9.6e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HMHBALJH_01320 4.5e-108 pncA Q Isochorismatase family
HMHBALJH_01321 9.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMHBALJH_01322 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMHBALJH_01323 3.3e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMHBALJH_01324 3.2e-240 ugpB G Bacterial extracellular solute-binding protein
HMHBALJH_01325 6.4e-148 ugpE G ABC transporter permease
HMHBALJH_01326 2.8e-163 ugpA P ABC-type sugar transport systems, permease components
HMHBALJH_01327 2.8e-210 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HMHBALJH_01328 5.4e-226 EGP Major facilitator Superfamily
HMHBALJH_01329 1.4e-147 3.5.2.6 V Beta-lactamase enzyme family
HMHBALJH_01330 1.7e-190 blaA6 V Beta-lactamase
HMHBALJH_01331 1.7e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMHBALJH_01332 3.4e-161 ybbH_2 K Helix-turn-helix domain, rpiR family
HMHBALJH_01333 5.8e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01334 5.4e-150 G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01335 1.8e-129 G PTS system sorbose-specific iic component
HMHBALJH_01337 2.8e-199 S endonuclease exonuclease phosphatase family protein
HMHBALJH_01338 2.1e-171 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMHBALJH_01339 4.2e-158 1.1.1.346 S reductase
HMHBALJH_01340 4.2e-74 adhR K helix_turn_helix, mercury resistance
HMHBALJH_01341 9.7e-143 Q Methyltransferase
HMHBALJH_01342 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMHBALJH_01343 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMHBALJH_01344 8.5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMHBALJH_01345 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMHBALJH_01346 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMHBALJH_01347 9.1e-245 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMHBALJH_01348 6.1e-82 yabR J RNA binding
HMHBALJH_01349 4.4e-65 divIC D cell cycle
HMHBALJH_01350 1.8e-38 yabO J S4 domain protein
HMHBALJH_01351 4.2e-281 yabM S Polysaccharide biosynthesis protein
HMHBALJH_01352 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMHBALJH_01353 2.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMHBALJH_01354 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMHBALJH_01355 5.9e-263 S Putative peptidoglycan binding domain
HMHBALJH_01356 1.3e-96 padR K Transcriptional regulator PadR-like family
HMHBALJH_01357 2.4e-246 XK27_06930 S ABC-2 family transporter protein
HMHBALJH_01358 9.9e-114 1.6.5.2 S Flavodoxin-like fold
HMHBALJH_01359 5.1e-119 S (CBS) domain
HMHBALJH_01360 6.8e-130 yciB M ErfK YbiS YcfS YnhG
HMHBALJH_01361 1.2e-279 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMHBALJH_01362 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HMHBALJH_01363 1.7e-85 S QueT transporter
HMHBALJH_01364 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HMHBALJH_01365 2.4e-37
HMHBALJH_01366 3.5e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMHBALJH_01367 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMHBALJH_01368 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMHBALJH_01369 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMHBALJH_01370 2.3e-147
HMHBALJH_01371 3.3e-123 S Tetratricopeptide repeat
HMHBALJH_01372 1.7e-122
HMHBALJH_01373 3e-72
HMHBALJH_01374 3.3e-42 rpmE2 J Ribosomal protein L31
HMHBALJH_01375 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMHBALJH_01376 6.4e-08
HMHBALJH_01378 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMHBALJH_01379 7e-220 ndh 1.6.99.3 C NADH dehydrogenase
HMHBALJH_01382 3e-151 S Protein of unknown function (DUF1211)
HMHBALJH_01383 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMHBALJH_01384 3.5e-79 ywiB S Domain of unknown function (DUF1934)
HMHBALJH_01385 1.9e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HMHBALJH_01386 9.6e-266 ywfO S HD domain protein
HMHBALJH_01387 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HMHBALJH_01388 4.2e-176 S DUF218 domain
HMHBALJH_01389 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMHBALJH_01390 8.1e-73
HMHBALJH_01391 1e-51 nudA S ASCH
HMHBALJH_01392 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMHBALJH_01393 1.5e-213 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMHBALJH_01394 3.5e-219 ysaA V RDD family
HMHBALJH_01395 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMHBALJH_01396 6.5e-119 ybbL S ABC transporter, ATP-binding protein
HMHBALJH_01397 1.8e-123 ybbM S Uncharacterised protein family (UPF0014)
HMHBALJH_01398 6.7e-159 czcD P cation diffusion facilitator family transporter
HMHBALJH_01399 9e-164 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMHBALJH_01400 1.1e-37 veg S Biofilm formation stimulator VEG
HMHBALJH_01401 5.5e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMHBALJH_01402 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMHBALJH_01403 1.3e-145 tatD L hydrolase, TatD family
HMHBALJH_01404 5e-79 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HMHBALJH_01405 2.1e-185 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HMHBALJH_01406 4.5e-171 yqhA G Aldose 1-epimerase
HMHBALJH_01407 1.3e-125 T LytTr DNA-binding domain
HMHBALJH_01408 1.1e-167 2.7.13.3 T GHKL domain
HMHBALJH_01409 9.2e-304 V ABC transporter
HMHBALJH_01410 0.0 V ABC transporter
HMHBALJH_01411 1.3e-28 K Transcriptional
HMHBALJH_01412 5.7e-66
HMHBALJH_01413 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMHBALJH_01414 4.1e-173 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HMHBALJH_01415 4.8e-11 gluP 3.4.21.105 S proteolysis
HMHBALJH_01416 8.6e-153 yunF F Protein of unknown function DUF72
HMHBALJH_01417 3.8e-92 3.6.1.55 F NUDIX domain
HMHBALJH_01418 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMHBALJH_01419 5.3e-107 yiiE S Protein of unknown function (DUF1211)
HMHBALJH_01420 5.7e-129 cobB K Sir2 family
HMHBALJH_01421 2.8e-17
HMHBALJH_01422 1.5e-169
HMHBALJH_01423 2.5e-97 yxkA S Phosphatidylethanolamine-binding protein
HMHBALJH_01425 1.6e-161 ypuA S Protein of unknown function (DUF1002)
HMHBALJH_01426 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMHBALJH_01427 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMHBALJH_01428 9.5e-286 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMHBALJH_01429 1e-173 S Aldo keto reductase
HMHBALJH_01430 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HMHBALJH_01431 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HMHBALJH_01432 1e-238 dinF V MatE
HMHBALJH_01434 3.3e-110 S TPM domain
HMHBALJH_01435 3.1e-102 lemA S LemA family
HMHBALJH_01436 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMHBALJH_01437 5.4e-74 EGP Major Facilitator Superfamily
HMHBALJH_01438 2e-252 gshR 1.8.1.7 C Glutathione reductase
HMHBALJH_01439 6.6e-176 proV E ABC transporter, ATP-binding protein
HMHBALJH_01440 4.9e-274 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMHBALJH_01442 0.0 helD 3.6.4.12 L DNA helicase
HMHBALJH_01443 2.7e-146 rlrG K Transcriptional regulator
HMHBALJH_01444 4.8e-174 shetA P Voltage-dependent anion channel
HMHBALJH_01445 2.5e-133 nodJ V ABC-2 type transporter
HMHBALJH_01446 4.9e-134 nodI V ABC transporter
HMHBALJH_01447 1.4e-130 ydfF K Transcriptional
HMHBALJH_01448 3.6e-109 S CAAX protease self-immunity
HMHBALJH_01450 1.5e-276 V ABC transporter transmembrane region
HMHBALJH_01451 3.6e-109 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMHBALJH_01452 7.2e-71 K MarR family
HMHBALJH_01453 0.0 uvrA3 L excinuclease ABC
HMHBALJH_01454 8.3e-190 yghZ C Aldo keto reductase family protein
HMHBALJH_01455 1.8e-142 S hydrolase
HMHBALJH_01456 1.2e-58
HMHBALJH_01457 4.8e-12
HMHBALJH_01458 1.3e-42
HMHBALJH_01459 5.1e-28
HMHBALJH_01461 3e-62 V ABC transporter
HMHBALJH_01463 2.6e-118 yoaK S Protein of unknown function (DUF1275)
HMHBALJH_01464 3.1e-127 yjhF G Phosphoglycerate mutase family
HMHBALJH_01465 5.8e-149 yitU 3.1.3.104 S hydrolase
HMHBALJH_01466 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMHBALJH_01467 1.7e-165 K LysR substrate binding domain
HMHBALJH_01468 3.9e-226 EK Aminotransferase, class I
HMHBALJH_01470 2.9e-45
HMHBALJH_01471 9.4e-58
HMHBALJH_01472 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMHBALJH_01473 7.3e-116 ydfK S Protein of unknown function (DUF554)
HMHBALJH_01474 5.1e-89
HMHBALJH_01475 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMHBALJH_01476 1.4e-63 S Family of unknown function (DUF5322)
HMHBALJH_01477 2.7e-67 rnhA 3.1.26.4 L Ribonuclease HI
HMHBALJH_01478 5.7e-109 XK27_02070 S Nitroreductase family
HMHBALJH_01479 2.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMHBALJH_01480 3.3e-55
HMHBALJH_01481 3.1e-270 K Mga helix-turn-helix domain
HMHBALJH_01482 4.5e-38 nrdH O Glutaredoxin
HMHBALJH_01483 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMHBALJH_01484 4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMHBALJH_01485 4.5e-163 K Transcriptional regulator
HMHBALJH_01486 0.0 pepO 3.4.24.71 O Peptidase family M13
HMHBALJH_01487 4.8e-193 lplA 6.3.1.20 H Lipoate-protein ligase
HMHBALJH_01488 1.5e-33
HMHBALJH_01489 1e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMHBALJH_01490 1.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMHBALJH_01492 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMHBALJH_01493 1.2e-105 ypsA S Belongs to the UPF0398 family
HMHBALJH_01494 3.3e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMHBALJH_01495 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMHBALJH_01496 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
HMHBALJH_01497 2.8e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMHBALJH_01498 4e-110 dnaD L DnaD domain protein
HMHBALJH_01499 2.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMHBALJH_01500 6.9e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMHBALJH_01501 6.1e-85 ypmB S Protein conserved in bacteria
HMHBALJH_01503 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMHBALJH_01504 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMHBALJH_01505 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMHBALJH_01506 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMHBALJH_01507 9.6e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMHBALJH_01508 3.4e-194 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMHBALJH_01509 3.5e-260 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMHBALJH_01510 7.2e-175
HMHBALJH_01511 5.9e-140
HMHBALJH_01512 9.7e-61 yitW S Iron-sulfur cluster assembly protein
HMHBALJH_01513 1.9e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMHBALJH_01514 2.9e-114 V (ABC) transporter
HMHBALJH_01515 1.7e-143 V (ABC) transporter
HMHBALJH_01516 1.3e-307 V ABC transporter transmembrane region
HMHBALJH_01517 6.3e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMHBALJH_01518 7.1e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMHBALJH_01519 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMHBALJH_01520 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMHBALJH_01521 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMHBALJH_01522 8.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMHBALJH_01523 6.5e-93 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HMHBALJH_01524 1.1e-06 S ABC-2 family transporter protein
HMHBALJH_01525 3.7e-123 V ATPases associated with a variety of cellular activities
HMHBALJH_01526 3.5e-54
HMHBALJH_01527 2.6e-149 recO L Involved in DNA repair and RecF pathway recombination
HMHBALJH_01528 1.2e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMHBALJH_01529 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMHBALJH_01530 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMHBALJH_01531 1.4e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMHBALJH_01532 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
HMHBALJH_01533 1.6e-68 yqeY S YqeY-like protein
HMHBALJH_01534 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMHBALJH_01535 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMHBALJH_01536 7.9e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMHBALJH_01537 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMHBALJH_01538 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMHBALJH_01539 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMHBALJH_01540 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMHBALJH_01541 1e-268
HMHBALJH_01542 1.5e-158 V ABC transporter
HMHBALJH_01543 7.7e-79 FG adenosine 5'-monophosphoramidase activity
HMHBALJH_01544 1.5e-247 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HMHBALJH_01545 7.9e-114 3.1.3.18 J HAD-hyrolase-like
HMHBALJH_01546 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMHBALJH_01547 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMHBALJH_01548 4e-53
HMHBALJH_01549 9.9e-124 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMHBALJH_01550 3e-173 prmA J Ribosomal protein L11 methyltransferase
HMHBALJH_01551 3.6e-85 XK27_03960 S Protein of unknown function (DUF3013)
HMHBALJH_01552 9.4e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMHBALJH_01553 3.1e-37
HMHBALJH_01554 9.7e-62 S Protein of unknown function (DUF1093)
HMHBALJH_01555 8.9e-26
HMHBALJH_01556 3.2e-61
HMHBALJH_01558 1e-71 L Belongs to the 'phage' integrase family
HMHBALJH_01559 8.1e-70 K Replication initiation factor
HMHBALJH_01561 5.4e-15 K sequence-specific DNA binding
HMHBALJH_01562 1.1e-38 S Phage derived protein Gp49-like (DUF891)
HMHBALJH_01563 6.6e-40 K Helix-turn-helix domain
HMHBALJH_01564 4.3e-22 yeeA V Type II restriction enzyme, methylase subunits
HMHBALJH_01565 5.4e-50 tra L Transposase and inactivated derivatives, IS30 family
HMHBALJH_01566 6.5e-164 L Transposase DDE domain
HMHBALJH_01567 2.8e-204 L Transposase DDE domain group 1
HMHBALJH_01568 5.8e-42 tra L Transposase and inactivated derivatives, IS30 family
HMHBALJH_01569 3.2e-62 K Transcriptional regulator
HMHBALJH_01570 4.2e-102 cadD P Cadmium resistance transporter
HMHBALJH_01571 6.9e-18 M Host cell surface-exposed lipoprotein
HMHBALJH_01572 2.2e-145 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HMHBALJH_01573 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HMHBALJH_01574 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMHBALJH_01575 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMHBALJH_01576 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMHBALJH_01577 7.1e-62
HMHBALJH_01578 1.4e-81 6.3.3.2 S ASCH
HMHBALJH_01579 5.9e-32
HMHBALJH_01580 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMHBALJH_01581 1.2e-187 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMHBALJH_01582 1e-286 dnaK O Heat shock 70 kDa protein
HMHBALJH_01583 1.4e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMHBALJH_01584 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMHBALJH_01585 1.7e-223 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMHBALJH_01586 2.5e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMHBALJH_01587 8.1e-160 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMHBALJH_01588 1.5e-118 terC P membrane
HMHBALJH_01589 7.8e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMHBALJH_01590 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMHBALJH_01591 5.4e-44 ylxQ J ribosomal protein
HMHBALJH_01592 1.5e-46 ylxR K Protein of unknown function (DUF448)
HMHBALJH_01593 2.5e-196 nusA K Participates in both transcription termination and antitermination
HMHBALJH_01594 1e-84 rimP J Required for maturation of 30S ribosomal subunits
HMHBALJH_01595 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMHBALJH_01596 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMHBALJH_01597 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMHBALJH_01598 4.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
HMHBALJH_01599 9.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMHBALJH_01600 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
HMHBALJH_01601 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HMHBALJH_01602 3e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01603 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HMHBALJH_01604 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMHBALJH_01605 1.8e-91 IQ KR domain
HMHBALJH_01606 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
HMHBALJH_01607 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HMHBALJH_01608 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
HMHBALJH_01609 6.3e-118 K helix_turn_helix gluconate operon transcriptional repressor
HMHBALJH_01610 3.4e-43 K Acetyltransferase (GNAT) family
HMHBALJH_01611 9.8e-213 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HMHBALJH_01612 6.2e-155 rihB 3.2.2.1 F Nucleoside
HMHBALJH_01613 4.9e-87 6.3.4.4 S Zeta toxin
HMHBALJH_01614 1.2e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HMHBALJH_01615 5.1e-48
HMHBALJH_01616 3.8e-203 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HMHBALJH_01617 2.1e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01618 1e-165 GKT transcriptional antiterminator
HMHBALJH_01619 1e-28
HMHBALJH_01620 1.6e-102
HMHBALJH_01621 2.1e-68 K helix_turn_helix multiple antibiotic resistance protein
HMHBALJH_01622 2.3e-238 ydiC1 EGP Major facilitator Superfamily
HMHBALJH_01623 6.7e-94
HMHBALJH_01624 4.5e-62
HMHBALJH_01625 1.7e-80
HMHBALJH_01626 4.9e-87 V AAA domain, putative AbiEii toxin, Type IV TA system
HMHBALJH_01627 5e-53
HMHBALJH_01628 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HMHBALJH_01629 3.2e-155 S Protein of unknown function (DUF2785)
HMHBALJH_01634 2.5e-36
HMHBALJH_01635 9.3e-44 K DNA-binding helix-turn-helix protein
HMHBALJH_01636 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMHBALJH_01637 1.1e-157 rbsB G Periplasmic binding protein domain
HMHBALJH_01638 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
HMHBALJH_01639 1.3e-269 rbsA 3.6.3.17 G ABC transporter
HMHBALJH_01640 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMHBALJH_01641 2.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HMHBALJH_01642 1.9e-272 E Amino acid permease
HMHBALJH_01643 3.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMHBALJH_01644 3.7e-103 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMHBALJH_01645 5.4e-150 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMHBALJH_01646 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
HMHBALJH_01647 1e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMHBALJH_01648 1.2e-109 P cobalt transport
HMHBALJH_01649 8.7e-243 P ABC transporter
HMHBALJH_01650 5.7e-95 S ABC-type cobalt transport system, permease component
HMHBALJH_01651 2.8e-27
HMHBALJH_01652 1.8e-34
HMHBALJH_01653 2.2e-274 nisT V ABC transporter
HMHBALJH_01655 2.3e-116 S Acetyltransferase (GNAT) family
HMHBALJH_01656 3.2e-292 E ABC transporter, substratebinding protein
HMHBALJH_01657 3.6e-235 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMHBALJH_01658 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_01659 3.8e-193 ypdE E M42 glutamyl aminopeptidase
HMHBALJH_01660 4.2e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_01661 6.7e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01662 2.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_01663 1.2e-181 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMHBALJH_01664 2.3e-226 4.4.1.8 E Aminotransferase, class I
HMHBALJH_01665 6.8e-205 S Uncharacterized protein conserved in bacteria (DUF2325)
HMHBALJH_01666 0.0 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMHBALJH_01667 2.9e-295 2.4.1.52 GT4 M Glycosyl transferases group 1
HMHBALJH_01668 7.8e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
HMHBALJH_01669 3e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_01670 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
HMHBALJH_01671 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01672 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HMHBALJH_01673 2.1e-224 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMHBALJH_01674 1.3e-218 agaS G SIS domain
HMHBALJH_01675 9e-130 XK27_08435 K UTRA
HMHBALJH_01676 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMHBALJH_01677 1.7e-82
HMHBALJH_01678 1.6e-238 malE G Bacterial extracellular solute-binding protein
HMHBALJH_01679 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HMHBALJH_01680 1.8e-119
HMHBALJH_01681 1.2e-157 sepS16B
HMHBALJH_01682 2.4e-235 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HMHBALJH_01683 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_01684 2.1e-144 K CAT RNA binding domain
HMHBALJH_01685 1.6e-260 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HMHBALJH_01686 4.7e-260 nox 1.6.3.4 C NADH oxidase
HMHBALJH_01687 1.7e-143 p75 M NlpC P60 family protein
HMHBALJH_01688 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HMHBALJH_01689 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMHBALJH_01690 1.1e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMHBALJH_01691 5.2e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_01692 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HMHBALJH_01693 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HMHBALJH_01694 1.8e-122 livF E ABC transporter
HMHBALJH_01695 3.6e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HMHBALJH_01696 1.7e-120 livM E Branched-chain amino acid transport system / permease component
HMHBALJH_01697 1.5e-150 livH U Branched-chain amino acid transport system / permease component
HMHBALJH_01698 1.4e-212 livJ E Receptor family ligand binding region
HMHBALJH_01699 3.5e-74 S Threonine/Serine exporter, ThrE
HMHBALJH_01700 5.6e-133 thrE S Putative threonine/serine exporter
HMHBALJH_01701 1.7e-43 trxC O Belongs to the thioredoxin family
HMHBALJH_01702 2e-17
HMHBALJH_01703 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
HMHBALJH_01704 0.0 pacL P P-type ATPase
HMHBALJH_01705 9.8e-64
HMHBALJH_01706 1.2e-225 EGP Major Facilitator Superfamily
HMHBALJH_01707 4.2e-311 mco Q Multicopper oxidase
HMHBALJH_01708 1e-24
HMHBALJH_01709 3.2e-110 2.5.1.105 P Cation efflux family
HMHBALJH_01710 8.7e-51 czrA K Transcriptional regulator, ArsR family
HMHBALJH_01711 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HMHBALJH_01712 9.5e-145 mtsB U ABC 3 transport family
HMHBALJH_01713 1.9e-130 mntB 3.6.3.35 P ABC transporter
HMHBALJH_01714 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMHBALJH_01715 2e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HMHBALJH_01716 1.4e-118 GM NmrA-like family
HMHBALJH_01717 1.8e-84
HMHBALJH_01718 3.9e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HMHBALJH_01719 4.7e-20
HMHBALJH_01721 5.9e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMHBALJH_01722 8.2e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMHBALJH_01723 1.2e-285 G MFS/sugar transport protein
HMHBALJH_01724 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
HMHBALJH_01725 4.6e-169 ssuA P NMT1-like family
HMHBALJH_01726 1.9e-294 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HMHBALJH_01727 5.6e-236 yfiQ I Acyltransferase family
HMHBALJH_01728 1.7e-120 ssuB P ATPases associated with a variety of cellular activities
HMHBALJH_01729 1.6e-146 ssuC U Binding-protein-dependent transport system inner membrane component
HMHBALJH_01730 1.4e-121 S B3/4 domain
HMHBALJH_01731 3.5e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMHBALJH_01732 7.3e-14
HMHBALJH_01733 0.0 V ABC transporter
HMHBALJH_01734 0.0 V ATPases associated with a variety of cellular activities
HMHBALJH_01735 2.5e-209 EGP Transmembrane secretion effector
HMHBALJH_01736 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HMHBALJH_01737 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMHBALJH_01738 1.1e-102 K Bacterial regulatory proteins, tetR family
HMHBALJH_01739 2.9e-185 yxeA V FtsX-like permease family
HMHBALJH_01740 1.4e-127 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HMHBALJH_01741 6.4e-34
HMHBALJH_01742 4.8e-137 tipA K TipAS antibiotic-recognition domain
HMHBALJH_01744 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMHBALJH_01745 3.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMHBALJH_01746 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMHBALJH_01747 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMHBALJH_01748 2.1e-120
HMHBALJH_01749 3.1e-60 rplQ J Ribosomal protein L17
HMHBALJH_01750 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMHBALJH_01751 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMHBALJH_01752 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMHBALJH_01753 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMHBALJH_01754 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMHBALJH_01755 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMHBALJH_01756 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMHBALJH_01757 2.2e-62 rplO J Binds to the 23S rRNA
HMHBALJH_01758 1.7e-24 rpmD J Ribosomal protein L30
HMHBALJH_01759 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMHBALJH_01760 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMHBALJH_01761 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMHBALJH_01762 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMHBALJH_01763 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMHBALJH_01764 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMHBALJH_01765 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMHBALJH_01766 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMHBALJH_01767 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HMHBALJH_01768 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMHBALJH_01769 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMHBALJH_01770 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMHBALJH_01771 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMHBALJH_01772 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMHBALJH_01773 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMHBALJH_01774 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
HMHBALJH_01775 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMHBALJH_01776 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMHBALJH_01777 1.2e-68 psiE S Phosphate-starvation-inducible E
HMHBALJH_01778 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HMHBALJH_01779 2.5e-197 yfjR K WYL domain
HMHBALJH_01780 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMHBALJH_01781 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMHBALJH_01782 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMHBALJH_01783 0.0 M domain protein
HMHBALJH_01784 2e-83 3.4.23.43
HMHBALJH_01785 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMHBALJH_01786 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMHBALJH_01787 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMHBALJH_01788 1.8e-78 ctsR K Belongs to the CtsR family
HMHBALJH_01790 4e-100 K CAT RNA binding domain
HMHBALJH_01791 1.6e-226 ptsG G phosphotransferase system
HMHBALJH_01792 2e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HMHBALJH_01793 1.3e-130 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HMHBALJH_01794 7.2e-68
HMHBALJH_01795 2.7e-149 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HMHBALJH_01797 1.3e-96
HMHBALJH_01800 5.1e-56 yjdF S Protein of unknown function (DUF2992)
HMHBALJH_01801 9e-112 S Bacteriocin-protection, YdeI or OmpD-Associated
HMHBALJH_01802 1.1e-253 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HMHBALJH_01803 7e-214 lsgC M Glycosyl transferases group 1
HMHBALJH_01804 2.8e-12
HMHBALJH_01805 0.0 yebA E Transglutaminase/protease-like homologues
HMHBALJH_01806 1e-131 yeaD S Protein of unknown function DUF58
HMHBALJH_01807 3.2e-167 yeaC S ATPase family associated with various cellular activities (AAA)
HMHBALJH_01808 6.3e-103 S Stage II sporulation protein M
HMHBALJH_01809 3.4e-100 ydaF J Acetyltransferase (GNAT) domain
HMHBALJH_01810 1.1e-264 glnP P ABC transporter
HMHBALJH_01811 2.7e-255 glnP P ABC transporter
HMHBALJH_01812 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMHBALJH_01813 1e-164 yniA G Phosphotransferase enzyme family
HMHBALJH_01814 1.3e-142 S AAA ATPase domain
HMHBALJH_01815 9.4e-286 ydbT S Bacterial PH domain
HMHBALJH_01816 1.9e-80 S Bacterial PH domain
HMHBALJH_01817 1.2e-52
HMHBALJH_01818 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
HMHBALJH_01819 6.3e-123 S Protein of unknown function (DUF975)
HMHBALJH_01820 1e-09
HMHBALJH_01821 1.5e-236 malE G Bacterial extracellular solute-binding protein
HMHBALJH_01822 2e-40
HMHBALJH_01823 4.1e-133 glnQ E ABC transporter, ATP-binding protein
HMHBALJH_01824 4e-287 glnP P ABC transporter permease
HMHBALJH_01825 3.3e-305 ybfG M peptidoglycan-binding domain-containing protein
HMHBALJH_01829 1.3e-157 K sequence-specific DNA binding
HMHBALJH_01830 4.2e-150 K Helix-turn-helix XRE-family like proteins
HMHBALJH_01831 2.3e-187 K Helix-turn-helix XRE-family like proteins
HMHBALJH_01832 9.8e-220 EGP Major facilitator Superfamily
HMHBALJH_01833 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_01834 1.6e-122 manY G PTS system
HMHBALJH_01835 8.7e-170 manN G system, mannose fructose sorbose family IID component
HMHBALJH_01836 4.4e-64 manO S Domain of unknown function (DUF956)
HMHBALJH_01837 4.3e-172 iolS C Aldo keto reductase
HMHBALJH_01838 3.5e-211 yeaN P Transporter, major facilitator family protein
HMHBALJH_01839 9.8e-253 ydiC1 EGP Major Facilitator Superfamily
HMHBALJH_01840 2.5e-112 ycaC Q Isochorismatase family
HMHBALJH_01841 2.3e-90 S AAA domain
HMHBALJH_01842 1.9e-81 F NUDIX domain
HMHBALJH_01843 1.7e-107 speG J Acetyltransferase (GNAT) domain
HMHBALJH_01844 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HMHBALJH_01845 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_01846 6.9e-130 K UbiC transcription regulator-associated domain protein
HMHBALJH_01847 1.7e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_01848 3.5e-73 S Domain of unknown function (DUF3284)
HMHBALJH_01849 2.6e-213 S Bacterial protein of unknown function (DUF871)
HMHBALJH_01850 1.4e-267 argH 4.3.2.1 E argininosuccinate lyase
HMHBALJH_01851 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMHBALJH_01852 9.3e-259 arpJ P ABC transporter permease
HMHBALJH_01853 1.1e-121 S Alpha/beta hydrolase family
HMHBALJH_01854 8.1e-131 K response regulator
HMHBALJH_01855 0.0 vicK 2.7.13.3 T Histidine kinase
HMHBALJH_01856 5.3e-259 yycH S YycH protein
HMHBALJH_01857 1.1e-141 yycI S YycH protein
HMHBALJH_01858 2.7e-154 vicX 3.1.26.11 S domain protein
HMHBALJH_01859 2.3e-10
HMHBALJH_01860 3.8e-206 htrA 3.4.21.107 O serine protease
HMHBALJH_01861 5.9e-70 S Iron-sulphur cluster biosynthesis
HMHBALJH_01862 1e-75 hsp3 O Hsp20/alpha crystallin family
HMHBALJH_01863 0.0 cadA P P-type ATPase
HMHBALJH_01864 3.1e-135
HMHBALJH_01865 2.1e-296 E ABC transporter, substratebinding protein
HMHBALJH_01866 6.6e-251 E Peptidase dimerisation domain
HMHBALJH_01867 2.1e-101
HMHBALJH_01868 4.1e-198 ybiR P Citrate transporter
HMHBALJH_01869 6.1e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMHBALJH_01870 3.6e-68 6.3.3.2 S ASCH
HMHBALJH_01871 3.5e-123
HMHBALJH_01872 5.4e-86 K Acetyltransferase (GNAT) domain
HMHBALJH_01873 6.3e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HMHBALJH_01874 1.5e-57 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HMHBALJH_01875 2.7e-80 MA20_25245 K FR47-like protein
HMHBALJH_01876 4.2e-107 S alpha beta
HMHBALJH_01877 3.5e-36
HMHBALJH_01878 8.6e-59
HMHBALJH_01880 1.1e-34 sugE U Multidrug resistance protein
HMHBALJH_01881 9.5e-91 S AAA-like domain
HMHBALJH_01882 1.5e-92 S SIR2-like domain
HMHBALJH_01883 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMHBALJH_01885 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HMHBALJH_01886 3.7e-52
HMHBALJH_01887 1.2e-40
HMHBALJH_01888 1.8e-275 pipD E Dipeptidase
HMHBALJH_01889 3.6e-82 ykhA 3.1.2.20 I Thioesterase superfamily
HMHBALJH_01890 0.0 helD 3.6.4.12 L DNA helicase
HMHBALJH_01891 6.8e-27
HMHBALJH_01892 0.0 yjbQ P TrkA C-terminal domain protein
HMHBALJH_01893 1.2e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMHBALJH_01894 2.9e-81 yjhE S Phage tail protein
HMHBALJH_01895 1.4e-216 mntH P H( )-stimulated, divalent metal cation uptake system
HMHBALJH_01896 4e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMHBALJH_01897 1.2e-128 pgm3 G Phosphoglycerate mutase family
HMHBALJH_01898 1.1e-169 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMHBALJH_01899 0.0 V FtsX-like permease family
HMHBALJH_01900 1.3e-134 cysA V ABC transporter, ATP-binding protein
HMHBALJH_01901 0.0 E amino acid
HMHBALJH_01902 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HMHBALJH_01903 4.5e-236 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMHBALJH_01904 1.3e-110 nodB3 G Polysaccharide deacetylase
HMHBALJH_01905 0.0 M Sulfatase
HMHBALJH_01906 3e-174 S EpsG family
HMHBALJH_01907 7.4e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
HMHBALJH_01908 3.6e-99 ywqC M capsule polysaccharide biosynthetic process
HMHBALJH_01909 1.6e-247 S polysaccharide biosynthetic process
HMHBALJH_01910 2.2e-199 M Glycosyl transferases group 1
HMHBALJH_01911 1.6e-121 tagF 2.7.8.12 M Glycosyltransferase like family 2
HMHBALJH_01912 1.3e-222 S Bacterial membrane protein, YfhO
HMHBALJH_01913 3.5e-299 M Glycosyl hydrolases family 25
HMHBALJH_01914 5.8e-179 M Dolichyl-phosphate-mannose-protein mannosyltransferase
HMHBALJH_01915 7.2e-112 icaC M Acyltransferase family
HMHBALJH_01916 1.3e-158 ykoT GT2 M Glycosyl transferase family 2
HMHBALJH_01917 7.8e-200 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMHBALJH_01918 6.2e-85
HMHBALJH_01919 1.5e-253 wcaJ M Bacterial sugar transferase
HMHBALJH_01920 1.1e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HMHBALJH_01921 1.6e-113 tuaG GT2 M Glycosyltransferase like family 2
HMHBALJH_01922 2.3e-173 cps2D 5.1.3.2 M RmlD substrate binding domain
HMHBALJH_01923 5.6e-110 glnP P ABC transporter permease
HMHBALJH_01924 7.9e-109 gluC P ABC transporter permease
HMHBALJH_01925 2.2e-148 glnH ET ABC transporter substrate-binding protein
HMHBALJH_01927 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMHBALJH_01928 5.7e-172
HMHBALJH_01930 5.6e-85 zur P Belongs to the Fur family
HMHBALJH_01931 1.8e-08
HMHBALJH_01932 2.7e-111 gmk2 2.7.4.8 F Guanylate kinase
HMHBALJH_01933 5.2e-66 K Acetyltransferase (GNAT) domain
HMHBALJH_01934 5e-125 spl M NlpC/P60 family
HMHBALJH_01935 5.9e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMHBALJH_01936 4.5e-161 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMHBALJH_01937 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HMHBALJH_01938 5.9e-174 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMHBALJH_01939 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HMHBALJH_01940 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMHBALJH_01941 3.1e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMHBALJH_01942 3.6e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HMHBALJH_01943 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMHBALJH_01944 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMHBALJH_01945 7.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMHBALJH_01946 2.5e-116 ylcC 3.4.22.70 M Sortase family
HMHBALJH_01947 3e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMHBALJH_01948 0.0 fbp 3.1.3.11 G phosphatase activity
HMHBALJH_01949 5.7e-65 nrp 1.20.4.1 P ArsC family
HMHBALJH_01950 0.0 clpL O associated with various cellular activities
HMHBALJH_01951 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
HMHBALJH_01952 5e-154 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMHBALJH_01953 3.9e-119 L Helix-turn-helix domain
HMHBALJH_01954 5.1e-178 S cellulase activity
HMHBALJH_01955 1.1e-14
HMHBALJH_01956 3.4e-53
HMHBALJH_01957 1.5e-42 hol S Bacteriophage holin
HMHBALJH_01958 1.9e-86 S peptidoglycan catabolic process
HMHBALJH_01960 3.3e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HMHBALJH_01961 1.4e-113 F DNA/RNA non-specific endonuclease
HMHBALJH_01962 4.1e-77 yttA 2.7.13.3 S Pfam Transposase IS66
HMHBALJH_01963 3e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
HMHBALJH_01964 1.7e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HMHBALJH_01965 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HMHBALJH_01971 1.1e-210 L PFAM transposase, IS4 family protein
HMHBALJH_01974 1.2e-17
HMHBALJH_01975 3.3e-193 yttB EGP Major facilitator Superfamily
HMHBALJH_01976 6.3e-284 pipD E Dipeptidase
HMHBALJH_01980 8.7e-09
HMHBALJH_01981 1.5e-132 G Phosphoglycerate mutase family
HMHBALJH_01982 1.1e-121 K Bacterial regulatory proteins, tetR family
HMHBALJH_01983 0.0 ycfI V ABC transporter, ATP-binding protein
HMHBALJH_01984 0.0 yfiC V ABC transporter
HMHBALJH_01985 2.5e-138 S NADPH-dependent FMN reductase
HMHBALJH_01986 2.3e-164 1.13.11.2 S glyoxalase
HMHBALJH_01987 8.9e-192 ampC V Beta-lactamase
HMHBALJH_01988 1e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMHBALJH_01989 6e-111 tdk 2.7.1.21 F thymidine kinase
HMHBALJH_01990 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMHBALJH_01991 3.6e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMHBALJH_01992 1.2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMHBALJH_01993 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMHBALJH_01994 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMHBALJH_01995 3.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HMHBALJH_01996 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMHBALJH_01997 2.6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMHBALJH_01998 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMHBALJH_01999 2.8e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMHBALJH_02000 1.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMHBALJH_02001 1.8e-08
HMHBALJH_02002 1.2e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMHBALJH_02003 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMHBALJH_02004 6.4e-32 ywzB S Protein of unknown function (DUF1146)
HMHBALJH_02005 4.5e-180 mbl D Cell shape determining protein MreB Mrl
HMHBALJH_02006 1.4e-25 epuA S DNA-directed RNA polymerase subunit beta
HMHBALJH_02007 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMHBALJH_02008 1.3e-31 S Protein of unknown function (DUF2969)
HMHBALJH_02009 7.6e-222 rodA D Belongs to the SEDS family
HMHBALJH_02010 1.2e-46 gcvH E glycine cleavage
HMHBALJH_02011 4.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMHBALJH_02012 1.9e-147 P Belongs to the nlpA lipoprotein family
HMHBALJH_02013 5e-148 P Belongs to the nlpA lipoprotein family
HMHBALJH_02014 9.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMHBALJH_02015 1.1e-105 metI P ABC transporter permease
HMHBALJH_02016 1.9e-141 sufC O FeS assembly ATPase SufC
HMHBALJH_02017 1.3e-190 sufD O FeS assembly protein SufD
HMHBALJH_02018 2.1e-224 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMHBALJH_02019 7.2e-77 nifU C SUF system FeS assembly protein, NifU family
HMHBALJH_02020 3.6e-279 sufB O assembly protein SufB
HMHBALJH_02021 1.8e-26
HMHBALJH_02022 8.4e-66 yueI S Protein of unknown function (DUF1694)
HMHBALJH_02023 1.2e-180 S Protein of unknown function (DUF2785)
HMHBALJH_02024 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HMHBALJH_02025 1.5e-83 usp6 T universal stress protein
HMHBALJH_02026 1.7e-39
HMHBALJH_02027 6e-239 rarA L recombination factor protein RarA
HMHBALJH_02028 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
HMHBALJH_02029 1.7e-72 yueI S Protein of unknown function (DUF1694)
HMHBALJH_02030 1.6e-106 yktB S Belongs to the UPF0637 family
HMHBALJH_02031 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMHBALJH_02032 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMHBALJH_02033 4.8e-120 G Phosphoglycerate mutase family
HMHBALJH_02034 1.2e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMHBALJH_02035 1.7e-165 IQ NAD dependent epimerase/dehydratase family
HMHBALJH_02036 2.7e-137 pnuC H nicotinamide mononucleotide transporter
HMHBALJH_02037 8.9e-133 dck 2.7.1.74 F deoxynucleoside kinase
HMHBALJH_02038 5.8e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HMHBALJH_02039 3.6e-307 oppA E ABC transporter, substratebinding protein
HMHBALJH_02040 5.6e-153 T GHKL domain
HMHBALJH_02041 4.7e-120 T Transcriptional regulatory protein, C terminal
HMHBALJH_02042 2.7e-166 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HMHBALJH_02043 4.1e-128 S ABC-2 family transporter protein
HMHBALJH_02044 9.7e-158 K Transcriptional regulator
HMHBALJH_02045 3.6e-78 yphH S Cupin domain
HMHBALJH_02046 2.7e-54 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMHBALJH_02047 3e-105 K Psort location Cytoplasmic, score
HMHBALJH_02048 1.7e-162 2.3.1.128 K Acetyltransferase (GNAT) domain
HMHBALJH_02049 6.5e-84 K Acetyltransferase (GNAT) domain
HMHBALJH_02051 8.6e-292 2.4.1.52 GT4 M Glycosyl transferases group 1
HMHBALJH_02052 8.7e-303 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMHBALJH_02053 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMHBALJH_02054 3.2e-95 yqaB S Acetyltransferase (GNAT) domain
HMHBALJH_02055 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMHBALJH_02056 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMHBALJH_02057 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMHBALJH_02058 9.1e-262 nylA 3.5.1.4 J Belongs to the amidase family
HMHBALJH_02059 3.6e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HMHBALJH_02060 3.8e-88 S ECF transporter, substrate-specific component
HMHBALJH_02061 5.2e-63 S Domain of unknown function (DUF4430)
HMHBALJH_02062 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HMHBALJH_02063 5e-78 F nucleoside 2-deoxyribosyltransferase
HMHBALJH_02064 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HMHBALJH_02065 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HMHBALJH_02066 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMHBALJH_02067 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMHBALJH_02068 2e-172 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMHBALJH_02069 2.5e-164 menA 2.5.1.74 M UbiA prenyltransferase family
HMHBALJH_02070 4.8e-196 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMHBALJH_02071 8e-224 tnpB L Putative transposase DNA-binding domain
HMHBALJH_02072 4.6e-139 cad S FMN_bind
HMHBALJH_02073 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HMHBALJH_02074 1.7e-81 ynhH S NusG domain II
HMHBALJH_02075 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HMHBALJH_02076 1.1e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMHBALJH_02077 4.6e-80
HMHBALJH_02078 1.4e-147 T Calcineurin-like phosphoesterase superfamily domain
HMHBALJH_02079 1.3e-162
HMHBALJH_02080 1.1e-156 V ATPases associated with a variety of cellular activities
HMHBALJH_02081 1.6e-219
HMHBALJH_02082 1.4e-193
HMHBALJH_02083 1.3e-122 1.5.1.40 S Rossmann-like domain
HMHBALJH_02084 4.2e-192 XK27_00915 C Luciferase-like monooxygenase
HMHBALJH_02085 1.2e-97 yacP S YacP-like NYN domain
HMHBALJH_02086 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMHBALJH_02087 5.5e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMHBALJH_02088 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMHBALJH_02089 7.9e-144 K sequence-specific DNA binding
HMHBALJH_02090 1.8e-246 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMHBALJH_02091 2.8e-105
HMHBALJH_02093 2.8e-258 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMHBALJH_02094 1.9e-139 yhfC S Putative membrane peptidase family (DUF2324)
HMHBALJH_02095 1.6e-156 S Membrane
HMHBALJH_02096 1.8e-60 K helix_turn_helix gluconate operon transcriptional repressor
HMHBALJH_02097 3.3e-226 inlJ M MucBP domain
HMHBALJH_02098 4e-113 K sequence-specific DNA binding
HMHBALJH_02099 1.8e-201 yacL S domain protein
HMHBALJH_02100 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMHBALJH_02101 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HMHBALJH_02102 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HMHBALJH_02103 8.8e-256 pepC 3.4.22.40 E aminopeptidase
HMHBALJH_02104 1.4e-261 pepC 3.4.22.40 E Peptidase C1-like family
HMHBALJH_02105 7.7e-197
HMHBALJH_02106 7.3e-209 S ABC-2 family transporter protein
HMHBALJH_02107 7.3e-166 V ATPases associated with a variety of cellular activities
HMHBALJH_02108 0.0 kup P Transport of potassium into the cell
HMHBALJH_02109 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HMHBALJH_02110 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
HMHBALJH_02111 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMHBALJH_02112 1.5e-200 ltrA S Bacterial low temperature requirement A protein (LtrA)
HMHBALJH_02113 7.2e-46
HMHBALJH_02114 9.6e-195 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMHBALJH_02115 1.2e-08 yhjA S CsbD-like
HMHBALJH_02116 1.8e-151 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMHBALJH_02117 1.9e-191 EGP Major facilitator Superfamily
HMHBALJH_02118 7.7e-116 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
HMHBALJH_02119 1.1e-170 EGP Major facilitator Superfamily
HMHBALJH_02120 4.1e-95 KT Purine catabolism regulatory protein-like family
HMHBALJH_02121 2.4e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMHBALJH_02122 3e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMHBALJH_02123 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMHBALJH_02124 1e-131 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMHBALJH_02125 1.4e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMHBALJH_02126 2.3e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HMHBALJH_02127 8.3e-207 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMHBALJH_02128 5.4e-147 Q Fumarylacetoacetate (FAA) hydrolase family
HMHBALJH_02129 7.5e-112 nfnB 1.5.1.34 C Nitroreductase family
HMHBALJH_02130 5.9e-70 K Acetyltransferase (GNAT) domain
HMHBALJH_02131 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
HMHBALJH_02132 3e-218 EGP Transmembrane secretion effector
HMHBALJH_02133 1.7e-128 T Transcriptional regulatory protein, C terminal
HMHBALJH_02134 1e-173 T Histidine kinase-like ATPases
HMHBALJH_02135 2.2e-134 XK27_05695 V ABC transporter, ATP-binding protein
HMHBALJH_02136 0.0 ysaB V FtsX-like permease family
HMHBALJH_02137 5.8e-208 xerS L Belongs to the 'phage' integrase family
HMHBALJH_02138 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMHBALJH_02139 5.2e-181 K LysR substrate binding domain
HMHBALJH_02140 2.1e-170 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMHBALJH_02141 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HMHBALJH_02142 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMHBALJH_02143 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMHBALJH_02144 6.9e-110 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMHBALJH_02145 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
HMHBALJH_02146 2.5e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMHBALJH_02147 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMHBALJH_02148 4.7e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HMHBALJH_02149 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMHBALJH_02150 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMHBALJH_02151 1.1e-144 dprA LU DNA protecting protein DprA
HMHBALJH_02152 9.6e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMHBALJH_02153 8.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMHBALJH_02154 1.6e-126 S Domain of unknown function (DUF4918)
HMHBALJH_02156 6.8e-56
HMHBALJH_02157 8e-258 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HMHBALJH_02158 2.3e-40 yozE S Belongs to the UPF0346 family
HMHBALJH_02159 1.8e-95 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMHBALJH_02160 2.4e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HMHBALJH_02161 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
HMHBALJH_02162 6.6e-148 DegV S EDD domain protein, DegV family
HMHBALJH_02163 8.1e-114 hly S protein, hemolysin III
HMHBALJH_02164 8.8e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMHBALJH_02165 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMHBALJH_02166 0.0 yfmR S ABC transporter, ATP-binding protein
HMHBALJH_02167 9.6e-85
HMHBALJH_02168 9.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMHBALJH_02169 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMHBALJH_02170 2.6e-236 S Tetratricopeptide repeat protein
HMHBALJH_02171 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMHBALJH_02172 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMHBALJH_02173 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HMHBALJH_02174 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMHBALJH_02175 3.8e-55 M Lysin motif
HMHBALJH_02176 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMHBALJH_02177 1.5e-178 ypbB 5.1.3.1 S Helix-turn-helix domain
HMHBALJH_02178 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
HMHBALJH_02179 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMHBALJH_02180 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMHBALJH_02181 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMHBALJH_02182 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMHBALJH_02183 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMHBALJH_02184 3.3e-166 xerD D recombinase XerD
HMHBALJH_02185 3.4e-163 cvfB S S1 domain
HMHBALJH_02186 7.2e-72 yeaL S Protein of unknown function (DUF441)
HMHBALJH_02187 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMHBALJH_02188 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMHBALJH_02189 0.0 dnaE 2.7.7.7 L DNA polymerase
HMHBALJH_02190 1.3e-19 S Protein of unknown function (DUF2929)
HMHBALJH_02191 9.2e-145
HMHBALJH_02192 4.7e-301 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HMHBALJH_02193 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
HMHBALJH_02194 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMHBALJH_02195 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMHBALJH_02196 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
HMHBALJH_02197 9.6e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HMHBALJH_02198 1.5e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMHBALJH_02199 0.0 oatA I Acyltransferase
HMHBALJH_02200 1.6e-233 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMHBALJH_02201 7.7e-132 fruR K DeoR C terminal sensor domain
HMHBALJH_02202 9.4e-156 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMHBALJH_02203 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HMHBALJH_02204 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMHBALJH_02205 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMHBALJH_02206 6.1e-258 glnPH2 P ABC transporter permease
HMHBALJH_02207 2.3e-20
HMHBALJH_02208 2.3e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HMHBALJH_02209 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HMHBALJH_02210 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMHBALJH_02211 2.1e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMHBALJH_02212 2.6e-311 yknV V ABC transporter
HMHBALJH_02213 9.3e-65 rmeD K helix_turn_helix, mercury resistance
HMHBALJH_02214 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMHBALJH_02215 4.8e-134 cobB K Sir2 family
HMHBALJH_02216 1.7e-82 M Protein of unknown function (DUF3737)
HMHBALJH_02217 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMHBALJH_02218 1.6e-160 S Tetratricopeptide repeat
HMHBALJH_02219 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMHBALJH_02220 1.5e-126
HMHBALJH_02221 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMHBALJH_02222 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HMHBALJH_02223 2.2e-193 holA 2.7.7.7 L DNA polymerase III delta subunit
HMHBALJH_02224 0.0 comEC S Competence protein ComEC
HMHBALJH_02225 4.2e-105 comEA L Competence protein ComEA
HMHBALJH_02226 7.9e-194 ylbL T Belongs to the peptidase S16 family
HMHBALJH_02227 4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMHBALJH_02228 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMHBALJH_02229 2.5e-56 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMHBALJH_02230 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMHBALJH_02231 6.5e-210 ftsW D Belongs to the SEDS family
HMHBALJH_02232 0.0 typA T GTP-binding protein TypA
HMHBALJH_02233 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMHBALJH_02234 3.2e-46 yktA S Belongs to the UPF0223 family
HMHBALJH_02235 8.3e-157 1.1.1.27 C L-malate dehydrogenase activity
HMHBALJH_02236 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
HMHBALJH_02237 3.1e-242 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMHBALJH_02238 1.8e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HMHBALJH_02239 1.1e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMHBALJH_02240 2.1e-135 S E1-E2 ATPase
HMHBALJH_02241 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMHBALJH_02242 2.5e-25
HMHBALJH_02243 2.4e-72
HMHBALJH_02245 4.9e-31 ykzG S Belongs to the UPF0356 family
HMHBALJH_02246 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMHBALJH_02247 8.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMHBALJH_02248 4.6e-243 els S Sterol carrier protein domain
HMHBALJH_02249 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMHBALJH_02250 1.4e-116 S Repeat protein
HMHBALJH_02251 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HMHBALJH_02253 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMHBALJH_02254 0.0 uvrA2 L ABC transporter
HMHBALJH_02255 2.6e-58 XK27_04120 S Putative amino acid metabolism
HMHBALJH_02256 9.9e-219 iscS 2.8.1.7 E Aminotransferase class V
HMHBALJH_02257 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMHBALJH_02258 5.8e-34
HMHBALJH_02259 3.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMHBALJH_02260 6.9e-116 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMHBALJH_02261 6.2e-208 yaaN P Toxic anion resistance protein (TelA)
HMHBALJH_02264 4.4e-169 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMHBALJH_02265 5.5e-180 D Alpha beta
HMHBALJH_02266 5.9e-185 lipA I Carboxylesterase family
HMHBALJH_02267 1e-215 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMHBALJH_02268 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_02269 0.0 mtlR K Mga helix-turn-helix domain
HMHBALJH_02270 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMHBALJH_02271 9.6e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMHBALJH_02272 8.6e-150 S haloacid dehalogenase-like hydrolase
HMHBALJH_02273 2.8e-44
HMHBALJH_02274 2e-14
HMHBALJH_02275 1.3e-137
HMHBALJH_02276 8.2e-221 spiA K IrrE N-terminal-like domain
HMHBALJH_02277 8.1e-151 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMHBALJH_02278 1e-125 V ABC transporter
HMHBALJH_02279 2.4e-207 bacI V MacB-like periplasmic core domain
HMHBALJH_02280 2.8e-179
HMHBALJH_02281 0.0 M Leucine rich repeats (6 copies)
HMHBALJH_02282 3e-223 mtnE 2.6.1.83 E Aminotransferase
HMHBALJH_02283 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HMHBALJH_02284 1.1e-149 M NLPA lipoprotein
HMHBALJH_02287 8.1e-199 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HMHBALJH_02288 3.3e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
HMHBALJH_02289 2.6e-80 S Threonine/Serine exporter, ThrE
HMHBALJH_02290 2.1e-132 thrE S Putative threonine/serine exporter
HMHBALJH_02292 3.8e-31
HMHBALJH_02293 1.4e-271 V ABC transporter transmembrane region
HMHBALJH_02295 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMHBALJH_02296 6.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMHBALJH_02297 1.9e-138 jag S R3H domain protein
HMHBALJH_02298 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMHBALJH_02299 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMHBALJH_02300 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMHBALJH_02301 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMHBALJH_02302 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMHBALJH_02303 2.9e-31 yaaA S S4 domain protein YaaA
HMHBALJH_02304 1.6e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMHBALJH_02305 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMHBALJH_02306 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMHBALJH_02307 1.7e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMHBALJH_02308 1.6e-73 ssb_2 L Single-strand binding protein family
HMHBALJH_02309 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HMHBALJH_02310 1.1e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMHBALJH_02311 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMHBALJH_02313 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
HMHBALJH_02314 4e-281 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HMHBALJH_02315 3.8e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HMHBALJH_02316 2.1e-28
HMHBALJH_02317 1.3e-85
HMHBALJH_02318 1.9e-91 S MucBP domain
HMHBALJH_02319 1.2e-117 ywnB S NAD(P)H-binding
HMHBALJH_02323 1.9e-117 E lipolytic protein G-D-S-L family
HMHBALJH_02324 1.7e-82 feoA P FeoA
HMHBALJH_02325 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMHBALJH_02326 2.7e-24 S Virus attachment protein p12 family
HMHBALJH_02327 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HMHBALJH_02328 1e-56
HMHBALJH_02329 1.3e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HMHBALJH_02330 2.2e-260 G MFS/sugar transport protein
HMHBALJH_02331 2.1e-73 S function, without similarity to other proteins
HMHBALJH_02332 1.4e-65
HMHBALJH_02333 0.0 macB_3 V ABC transporter, ATP-binding protein
HMHBALJH_02334 3e-257 dtpT U amino acid peptide transporter
HMHBALJH_02335 1.7e-156 yjjH S Calcineurin-like phosphoesterase
HMHBALJH_02337 2.1e-261 mga K Mga helix-turn-helix domain
HMHBALJH_02338 6.5e-284 sprD D Domain of Unknown Function (DUF1542)
HMHBALJH_02339 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HMHBALJH_02340 4.5e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMHBALJH_02341 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMHBALJH_02342 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
HMHBALJH_02343 6.1e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMHBALJH_02344 1.1e-220 V Beta-lactamase
HMHBALJH_02345 1.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMHBALJH_02346 2.7e-216 V Beta-lactamase
HMHBALJH_02348 0.0 pacL 3.6.3.8 P P-type ATPase
HMHBALJH_02349 1.3e-70
HMHBALJH_02350 8.9e-176 XK27_08835 S ABC transporter
HMHBALJH_02351 1.3e-128 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMHBALJH_02352 7.3e-130 XK27_08845 S ABC transporter, ATP-binding protein
HMHBALJH_02353 5.2e-83 ydcK S Belongs to the SprT family
HMHBALJH_02354 6.6e-81 yodP 2.3.1.264 K FR47-like protein
HMHBALJH_02356 5.4e-08
HMHBALJH_02357 2.5e-32
HMHBALJH_02358 7.4e-34
HMHBALJH_02359 4.9e-224 pimH EGP Major facilitator Superfamily
HMHBALJH_02360 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMHBALJH_02361 8.6e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMHBALJH_02363 3.8e-96
HMHBALJH_02364 1.8e-134 3.4.22.70 M Sortase family
HMHBALJH_02365 1.3e-295 M Cna protein B-type domain
HMHBALJH_02366 1.4e-264 M domain protein
HMHBALJH_02367 0.0 M domain protein
HMHBALJH_02368 3.3e-103
HMHBALJH_02369 3.5e-227 N Uncharacterized conserved protein (DUF2075)
HMHBALJH_02370 2.7e-207 MA20_36090 S Protein of unknown function (DUF2974)
HMHBALJH_02371 2.2e-111 K Helix-turn-helix XRE-family like proteins
HMHBALJH_02372 5.2e-56 K Transcriptional regulator PadR-like family
HMHBALJH_02373 4.2e-136
HMHBALJH_02374 2.7e-135
HMHBALJH_02375 1.5e-43 S Enterocin A Immunity
HMHBALJH_02376 1.6e-186 tas C Aldo/keto reductase family
HMHBALJH_02377 9.4e-253 yjjP S Putative threonine/serine exporter
HMHBALJH_02378 7.8e-58
HMHBALJH_02379 1.6e-228 mesE M Transport protein ComB
HMHBALJH_02380 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMHBALJH_02382 2.2e-78 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMHBALJH_02383 3.8e-137 plnD K LytTr DNA-binding domain
HMHBALJH_02386 1.4e-44 spiA S Enterocin A Immunity
HMHBALJH_02387 2.9e-20
HMHBALJH_02391 5.8e-133 S CAAX protease self-immunity
HMHBALJH_02392 2.5e-69 K Transcriptional regulator
HMHBALJH_02393 1.4e-251 EGP Major Facilitator Superfamily
HMHBALJH_02394 2.4e-53
HMHBALJH_02395 2.3e-54 S Enterocin A Immunity
HMHBALJH_02396 2.6e-180 S Aldo keto reductase
HMHBALJH_02397 1.2e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMHBALJH_02398 1.5e-214 yqiG C Oxidoreductase
HMHBALJH_02399 1.3e-16 S Short C-terminal domain
HMHBALJH_02400 3.3e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMHBALJH_02401 2.2e-135
HMHBALJH_02402 7.6e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMHBALJH_02403 1.4e-300 frvR K Mga helix-turn-helix domain
HMHBALJH_02404 7.7e-296 frvR K Mga helix-turn-helix domain
HMHBALJH_02405 9.4e-267 lysP E amino acid
HMHBALJH_02407 5.3e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HMHBALJH_02408 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMHBALJH_02409 1.6e-97
HMHBALJH_02410 8.8e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
HMHBALJH_02411 3.6e-188 S Bacterial protein of unknown function (DUF916)
HMHBALJH_02412 9.9e-103
HMHBALJH_02413 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMHBALJH_02414 1.4e-156 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMHBALJH_02415 1.7e-156 I alpha/beta hydrolase fold
HMHBALJH_02416 9.7e-48
HMHBALJH_02417 2.5e-68
HMHBALJH_02418 7.9e-46
HMHBALJH_02419 1.5e-155 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMHBALJH_02420 7.2e-124 citR K FCD
HMHBALJH_02421 4.5e-266 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HMHBALJH_02422 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMHBALJH_02423 4.7e-285 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HMHBALJH_02424 1.7e-154 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HMHBALJH_02425 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HMHBALJH_02426 9.3e-181 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMHBALJH_02428 1.3e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HMHBALJH_02429 6.7e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
HMHBALJH_02430 1.8e-48
HMHBALJH_02431 2.2e-241 citM C Citrate transporter
HMHBALJH_02432 1.3e-41
HMHBALJH_02433 2.5e-98 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HMHBALJH_02434 7.9e-88 K Acetyltransferase (GNAT) domain
HMHBALJH_02435 2.4e-107 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HMHBALJH_02436 3.7e-57 K Transcriptional regulator PadR-like family
HMHBALJH_02437 4.6e-64 ORF00048
HMHBALJH_02438 1.6e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMHBALJH_02439 6.1e-163 yjjC V ABC transporter
HMHBALJH_02440 1.1e-284 M Exporter of polyketide antibiotics
HMHBALJH_02441 1.8e-113 K Transcriptional regulator
HMHBALJH_02442 2.2e-257 ypiB EGP Major facilitator Superfamily
HMHBALJH_02443 6.7e-128 S membrane transporter protein
HMHBALJH_02444 1.9e-184 K Helix-turn-helix domain
HMHBALJH_02445 4.2e-247 S peptidoglycan catabolic process
HMHBALJH_02446 1.8e-21
HMHBALJH_02447 6e-74 S Pfam:Phage_TTP_1
HMHBALJH_02448 1.5e-30
HMHBALJH_02449 2.3e-63 S exonuclease activity
HMHBALJH_02450 2.3e-38 S Phage head-tail joining protein
HMHBALJH_02451 2.1e-26 S Phage gp6-like head-tail connector protein
HMHBALJH_02452 8e-22 S peptidase activity
HMHBALJH_02453 2.5e-201 S peptidase activity
HMHBALJH_02454 6.8e-105 S peptidase activity
HMHBALJH_02455 1e-224 S Phage portal protein
HMHBALJH_02457 0.0 S Phage Terminase
HMHBALJH_02458 8.7e-78 S Phage terminase, small subunit
HMHBALJH_02459 2.3e-73 L HNH nucleases
HMHBALJH_02461 1.4e-42
HMHBALJH_02462 1e-26
HMHBALJH_02465 1.6e-76
HMHBALJH_02467 1.6e-38 S YopX protein
HMHBALJH_02470 2.2e-28
HMHBALJH_02472 2.2e-56 S Protein of unknown function (DUF1642)
HMHBALJH_02473 3e-24
HMHBALJH_02474 2.5e-27
HMHBALJH_02475 7.8e-55 rusA L Endodeoxyribonuclease RusA
HMHBALJH_02477 5.9e-233 S DNA helicase activity
HMHBALJH_02478 3.1e-150 S calcium ion binding
HMHBALJH_02482 7.4e-16
HMHBALJH_02485 1.5e-84 S Phage regulatory protein Rha (Phage_pRha)
HMHBALJH_02486 2.5e-22 K BRO family, N-terminal domain
HMHBALJH_02487 1.5e-10
HMHBALJH_02489 2.4e-59 ps115 K Helix-turn-helix XRE-family like proteins
HMHBALJH_02490 3.9e-19 E Zn peptidase
HMHBALJH_02491 8.7e-115
HMHBALJH_02493 1.3e-07
HMHBALJH_02495 1e-09
HMHBALJH_02496 2.8e-210 L Belongs to the 'phage' integrase family
HMHBALJH_02498 6.8e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMHBALJH_02499 2.7e-70 S Domain of unknown function (DUF3284)
HMHBALJH_02500 6.5e-212 S Bacterial protein of unknown function (DUF871)
HMHBALJH_02501 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HMHBALJH_02502 9.1e-101
HMHBALJH_02503 1.6e-148 lutA C Cysteine-rich domain
HMHBALJH_02504 4e-289 lutB C 4Fe-4S dicluster domain
HMHBALJH_02505 5.2e-130 yrjD S LUD domain
HMHBALJH_02506 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMHBALJH_02507 1.5e-253 EGP Major facilitator Superfamily
HMHBALJH_02509 2.5e-305 oppA E ABC transporter, substratebinding protein
HMHBALJH_02510 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMHBALJH_02511 3.1e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMHBALJH_02512 1.9e-197 oppD P Belongs to the ABC transporter superfamily
HMHBALJH_02513 2.4e-181 oppF P Belongs to the ABC transporter superfamily
HMHBALJH_02514 1.4e-113 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HMHBALJH_02515 4.9e-48 K Cro/C1-type HTH DNA-binding domain
HMHBALJH_02516 2.4e-36 XK27_01315 S Protein of unknown function (DUF2829)
HMHBALJH_02517 3.5e-126 IQ Enoyl-(Acyl carrier protein) reductase
HMHBALJH_02518 4.9e-82 ccl S QueT transporter
HMHBALJH_02519 1.1e-130 E lipolytic protein G-D-S-L family
HMHBALJH_02520 1.4e-119 epsB M biosynthesis protein
HMHBALJH_02521 1e-104 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMHBALJH_02522 2.4e-29 2.4.1.166 GT2 M Glycosyltransferase like family 2
HMHBALJH_02523 1.3e-92 cps2J S Polysaccharide biosynthesis protein
HMHBALJH_02524 1.3e-41 2.4.1.315 GT2 M Glycosyltransferase like family 2
HMHBALJH_02525 1.8e-20 S EpsG family
HMHBALJH_02526 3.5e-31 2.7.8.12 GT2 S Glycosyltransferase like family 2
HMHBALJH_02527 6e-42 epsI GM Polysaccharide pyruvyl transferase
HMHBALJH_02528 7.3e-81 GT4 M COG0438 Glycosyltransferase
HMHBALJH_02529 1.7e-53 capM M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMHBALJH_02530 1.5e-82 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
HMHBALJH_02531 6.7e-162 V ABC transporter
HMHBALJH_02532 1.1e-187 amtB P Ammonium Transporter Family
HMHBALJH_02533 7.8e-213 P Pyridine nucleotide-disulphide oxidoreductase
HMHBALJH_02534 6.9e-125 usp 3.5.1.28 CBM50 D CHAP domain
HMHBALJH_02535 0.0 ylbB V ABC transporter permease
HMHBALJH_02536 1.1e-127 macB V ABC transporter, ATP-binding protein
HMHBALJH_02537 2.5e-95 K transcriptional regulator
HMHBALJH_02538 2.9e-153 supH G Sucrose-6F-phosphate phosphohydrolase
HMHBALJH_02539 1.4e-45
HMHBALJH_02540 4.1e-128 S membrane transporter protein
HMHBALJH_02541 2.1e-103 S Protein of unknown function (DUF1211)
HMHBALJH_02542 1.7e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HMHBALJH_02543 1.3e-54
HMHBALJH_02544 8.1e-287 pipD E Dipeptidase
HMHBALJH_02545 2.3e-105 S Membrane
HMHBALJH_02546 1.9e-84
HMHBALJH_02547 2.2e-52
HMHBALJH_02548 4.9e-52
HMHBALJH_02549 1.1e-179 ybfG M peptidoglycan-binding domain-containing protein
HMHBALJH_02550 2.4e-122 azlC E branched-chain amino acid
HMHBALJH_02551 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HMHBALJH_02552 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HMHBALJH_02553 0.0 M Glycosyl hydrolase family 59
HMHBALJH_02554 2.5e-163 K helix_turn_helix, arabinose operon control protein
HMHBALJH_02555 6.3e-263 lysP E amino acid
HMHBALJH_02556 2e-277 ygjI E Amino Acid
HMHBALJH_02557 0.0 ebgA 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMHBALJH_02559 8.5e-98 K Transcriptional regulator, LysR family
HMHBALJH_02560 3.9e-227 E Peptidase family M20/M25/M40
HMHBALJH_02561 7.1e-223 G Major Facilitator Superfamily
HMHBALJH_02562 8.2e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HMHBALJH_02563 2.9e-173 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMHBALJH_02564 0.0 mtlF 2.7.1.197 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMHBALJH_02565 5.3e-93 hxlB 4.1.2.43, 5.3.1.27 M SIS domain
HMHBALJH_02566 3.9e-108 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HMHBALJH_02567 6.2e-129 fruR K DeoR C terminal sensor domain
HMHBALJH_02568 9e-108 S Haloacid dehalogenase-like hydrolase
HMHBALJH_02570 3.5e-49
HMHBALJH_02571 1.8e-145 levD G PTS system mannose/fructose/sorbose family IID component
HMHBALJH_02572 4.1e-137 M PTS system sorbose-specific iic component
HMHBALJH_02573 1.1e-86 2.7.1.191 G PTS system sorbose subfamily IIB component
HMHBALJH_02574 8.1e-57 levA G PTS system fructose IIA component
HMHBALJH_02575 0.0 K Sigma-54 interaction domain
HMHBALJH_02576 2.8e-143 K helix_turn_helix, arabinose operon control protein
HMHBALJH_02577 0.0 S PglZ domain
HMHBALJH_02578 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
HMHBALJH_02579 0.0 S Protein of unknown function (DUF1524)
HMHBALJH_02580 9.2e-123
HMHBALJH_02581 5.1e-221 F Permease for cytosine/purines, uracil, thiamine, allantoin
HMHBALJH_02582 6.9e-206 S Protein of unknown function (DUF917)
HMHBALJH_02583 6.7e-287 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HMHBALJH_02584 0.0 G Phosphodiester glycosidase
HMHBALJH_02585 6e-146 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HMHBALJH_02586 9e-102 S WxL domain surface cell wall-binding
HMHBALJH_02587 5.1e-110
HMHBALJH_02588 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HMHBALJH_02589 4.2e-130 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HMHBALJH_02590 5e-131 S Belongs to the UPF0246 family
HMHBALJH_02591 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMHBALJH_02592 2.1e-151 aatB ET ABC transporter substrate-binding protein
HMHBALJH_02593 3.8e-111 glnQ 3.6.3.21 E ABC transporter
HMHBALJH_02594 4.7e-109 artQ P ABC transporter permease
HMHBALJH_02595 1.3e-140 minD D Belongs to the ParA family
HMHBALJH_02596 1.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMHBALJH_02597 4.7e-83 mreD M rod shape-determining protein MreD
HMHBALJH_02598 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HMHBALJH_02599 1e-179 mreB D cell shape determining protein MreB
HMHBALJH_02600 2e-118 radC L DNA repair protein
HMHBALJH_02601 8.7e-116 S Haloacid dehalogenase-like hydrolase
HMHBALJH_02602 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMHBALJH_02603 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMHBALJH_02604 1.3e-114 rex K CoA binding domain
HMHBALJH_02605 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMHBALJH_02606 1.7e-215 iscS2 2.8.1.7 E Aminotransferase class V
HMHBALJH_02607 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMHBALJH_02608 1.7e-84 ytsP 1.8.4.14 T GAF domain-containing protein
HMHBALJH_02609 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMHBALJH_02610 2.2e-16 S Domain of unknown function (DUF4263)
HMHBALJH_02611 1.8e-193 S Domain of unknown function DUF87
HMHBALJH_02612 9.7e-60 S SIR2-like domain
HMHBALJH_02613 4.8e-44 L Transposase DDE domain
HMHBALJH_02614 1.2e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMHBALJH_02615 1.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMHBALJH_02616 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMHBALJH_02617 2.6e-236 pyrP F Permease
HMHBALJH_02618 7.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMHBALJH_02619 2.1e-238 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMHBALJH_02620 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMHBALJH_02621 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMHBALJH_02622 4.2e-153 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMHBALJH_02623 4.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMHBALJH_02624 5.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMHBALJH_02625 3.2e-193 pfoS S Phosphotransferase system, EIIC
HMHBALJH_02626 6.2e-51 S MazG-like family
HMHBALJH_02627 0.0 FbpA K Fibronectin-binding protein
HMHBALJH_02628 1.3e-06
HMHBALJH_02629 3.2e-161 degV S EDD domain protein, DegV family
HMHBALJH_02630 5.8e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
HMHBALJH_02631 3.3e-208 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HMHBALJH_02632 9.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMHBALJH_02633 3.5e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMHBALJH_02634 3.2e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMHBALJH_02635 1.7e-09 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMHBALJH_02636 3.6e-263 ydiC1 EGP Major facilitator Superfamily
HMHBALJH_02637 1.5e-145 pstS P Phosphate
HMHBALJH_02638 8.2e-37 cspA K Cold shock protein
HMHBALJH_02639 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMHBALJH_02640 1.9e-80 divIVA D DivIVA protein
HMHBALJH_02641 6.4e-145 ylmH S S4 domain protein
HMHBALJH_02642 3.4e-43 yggT D integral membrane protein
HMHBALJH_02643 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMHBALJH_02644 3.1e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMHBALJH_02645 6.9e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMHBALJH_02646 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMHBALJH_02647 1.4e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMHBALJH_02648 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMHBALJH_02649 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMHBALJH_02650 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMHBALJH_02651 6.2e-58 ftsL D cell division protein FtsL
HMHBALJH_02652 1.8e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMHBALJH_02653 7e-77 mraZ K Belongs to the MraZ family
HMHBALJH_02654 4.2e-53
HMHBALJH_02655 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMHBALJH_02656 4.1e-66 L Transposase DDE domain
HMHBALJH_02657 2.5e-15 M LysM domain
HMHBALJH_02659 1.3e-24 K Cro/C1-type HTH DNA-binding domain
HMHBALJH_02661 1.5e-37 L Plasmid pRiA4b ORF-3-like protein
HMHBALJH_02662 2.6e-47 lciIC K Helix-turn-helix XRE-family like proteins
HMHBALJH_02663 0.0 lytN 3.5.1.104 M LysM domain
HMHBALJH_02665 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HMHBALJH_02666 1.9e-114 zmp3 O Zinc-dependent metalloprotease
HMHBALJH_02667 4.2e-134 2.7.1.39 S Phosphotransferase enzyme family
HMHBALJH_02668 9.3e-68 S Iron-sulphur cluster biosynthesis
HMHBALJH_02669 2.3e-282 V ABC transporter transmembrane region
HMHBALJH_02670 1.3e-285 V ABC transporter transmembrane region
HMHBALJH_02671 6.7e-38
HMHBALJH_02672 9.7e-155 S Uncharacterised protein, DegV family COG1307
HMHBALJH_02673 3.1e-102 desR K helix_turn_helix, Lux Regulon
HMHBALJH_02674 7.5e-200 desK 2.7.13.3 T Histidine kinase
HMHBALJH_02675 1.5e-127 yvfS V ABC-2 type transporter
HMHBALJH_02676 5.7e-158 yvfR V ABC transporter
HMHBALJH_02677 2.5e-275
HMHBALJH_02678 2.5e-181
HMHBALJH_02679 0.0 D Putative exonuclease SbcCD, C subunit
HMHBALJH_02680 2.2e-132 S Protein of unknown function C-terminus (DUF2399)
HMHBALJH_02681 2.2e-82 K Acetyltransferase (GNAT) domain
HMHBALJH_02682 0.0 yhgF K Tex-like protein N-terminal domain protein
HMHBALJH_02683 7.4e-82
HMHBALJH_02684 1.1e-138 puuD S peptidase C26
HMHBALJH_02685 1e-227 steT E Amino acid permease
HMHBALJH_02688 1.7e-72 L Transposase DDE domain
HMHBALJH_02689 4.3e-64 yugI 5.3.1.9 J general stress protein
HMHBALJH_02690 1.7e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMHBALJH_02691 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMHBALJH_02692 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HMHBALJH_02693 8.9e-116 dedA S SNARE-like domain protein
HMHBALJH_02694 7.3e-115 S Protein of unknown function (DUF1461)
HMHBALJH_02695 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMHBALJH_02696 2.6e-109 yutD S Protein of unknown function (DUF1027)
HMHBALJH_02697 1.3e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMHBALJH_02698 5.3e-115 S Calcineurin-like phosphoesterase
HMHBALJH_02699 5.9e-116 yibF S overlaps another CDS with the same product name
HMHBALJH_02700 1.9e-187 yibE S overlaps another CDS with the same product name
HMHBALJH_02701 6.1e-54
HMHBALJH_02702 2.8e-257 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HMHBALJH_02703 5.5e-272 pepV 3.5.1.18 E dipeptidase PepV
HMHBALJH_02704 6.3e-134 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMHBALJH_02705 4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HMHBALJH_02724 1.3e-93 sigH K Sigma-70 region 2
HMHBALJH_02725 1.9e-297 ybeC E amino acid
HMHBALJH_02726 1.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMHBALJH_02727 1e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMHBALJH_02728 4.5e-167 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMHBALJH_02729 2.6e-219 patA 2.6.1.1 E Aminotransferase
HMHBALJH_02730 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
HMHBALJH_02731 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMHBALJH_02732 5.3e-80 perR P Belongs to the Fur family
HMHBALJH_02733 2.3e-311 E Bacterial extracellular solute-binding proteins, family 5 Middle
HMHBALJH_02734 5e-168 oppB P Binding-protein-dependent transport system inner membrane component
HMHBALJH_02735 8.8e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
HMHBALJH_02736 1.7e-48
HMHBALJH_02737 6.8e-198 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HMHBALJH_02738 5.7e-158 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HMHBALJH_02739 1.1e-87 V ATPases associated with a variety of cellular activities
HMHBALJH_02740 9.1e-155
HMHBALJH_02741 1e-16
HMHBALJH_02742 1.6e-126 skfE V ATPases associated with a variety of cellular activities
HMHBALJH_02743 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
HMHBALJH_02744 3.8e-159 S Alpha beta hydrolase
HMHBALJH_02745 2.4e-93 K Bacterial regulatory proteins, tetR family
HMHBALJH_02746 1e-51 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMHBALJH_02747 7.4e-64
HMHBALJH_02748 1.4e-53
HMHBALJH_02749 6.3e-216 S Domain of unknown function (DUF389)
HMHBALJH_02750 1.1e-234 yagE E Amino acid permease
HMHBALJH_02751 3.5e-131 tnp L DDE domain
HMHBALJH_02752 1.3e-254 G Major Facilitator Superfamily
HMHBALJH_02753 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMHBALJH_02754 8.8e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMHBALJH_02756 4.9e-52 ypaA S Protein of unknown function (DUF1304)
HMHBALJH_02757 1.3e-55 D Alpha beta
HMHBALJH_02758 3.1e-93 L Transposase
HMHBALJH_02759 1.1e-121 L Transposase
HMHBALJH_02760 3.2e-253 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HMHBALJH_02761 2.7e-239 cycA E Amino acid permease
HMHBALJH_02762 4.9e-203 S cellulase activity
HMHBALJH_02763 1.1e-14
HMHBALJH_02764 3.4e-53
HMHBALJH_02765 1.8e-42 hol S Bacteriophage holin
HMHBALJH_02766 2.9e-227 M Glycosyl hydrolases family 25
HMHBALJH_02769 1.5e-99
HMHBALJH_02770 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMHBALJH_02771 9.9e-45 L hmm pf00665
HMHBALJH_02772 4.1e-120 codB_1 F cytosine purines uracil thiamine allantoin
HMHBALJH_02773 2.3e-116 S Protein of unknown function (DUF917)
HMHBALJH_02774 1e-170 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HMHBALJH_02775 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HMHBALJH_02776 1.6e-154 tesE Q hydratase
HMHBALJH_02777 1.7e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)