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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	Description
PIEKEEEF_00001	8e-185	yumC	1.18.1.2, 1.19.1.1, 1.8.1.9		C	Ferredoxin--NADP reductase
PIEKEEEF_00002	3e-116	dedA			S	SNARE-like domain protein
PIEKEEEF_00003	3.7e-100				S	Protein of unknown function (DUF1461)
PIEKEEEF_00004	6.9e-144	nagD	2.7.1.25, 3.1.3.41		G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIEKEEEF_00005	2.2e-105	yutD			S	Protein of unknown function (DUF1027)
PIEKEEEF_00006	9.8e-274	yunD	3.1.3.5		F	Belongs to the 5'-nucleotidase family
PIEKEEEF_00007	4.3e-55
PIEKEEEF_00008	2.3e-267	ugpQ	3.1.4.46		C	glycerophosphoryl diester phosphodiesterase
PIEKEEEF_00009	6.4e-182	ccpA			K	catabolite control protein A
PIEKEEEF_00010	1.6e-213	pepQ	3.4.13.9		E	Creatinase/Prolidase N-terminal domain
PIEKEEEF_00011	1.9e-35
PIEKEEEF_00012	1e-08	WQ51_05790			S	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIEKEEEF_00013	3.7e-146	ykuT			M	mechanosensitive ion channel
PIEKEEEF_00014	5.3e-100				V	ATPases associated with a variety of cellular activities
PIEKEEEF_00015	4.9e-139
PIEKEEEF_00016	3e-103
PIEKEEEF_00017	1.3e-39	ropB			K	Helix-turn-helix domain
PIEKEEEF_00018	3.9e-113	rdgB	3.6.1.66, 5.1.1.3		F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIEKEEEF_00019	6.6e-145	murI	3.6.1.66, 5.1.1.3		M	Provides the (R)-glutamate required for cell wall biosynthesis
PIEKEEEF_00020	1.1e-71	yslB			S	Protein of unknown function (DUF2507)
PIEKEEEF_00021	1.3e-58	mscL			M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIEKEEEF_00022	3.5e-54	trxA			O	Belongs to the thioredoxin family
PIEKEEEF_00023	0.0	mutS2			L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIEKEEEF_00024	1.1e-50	yrzB			S	Belongs to the UPF0473 family
PIEKEEEF_00025	6.1e-73	yqgF			J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIEKEEEF_00026	2e-42	yrzL			S	Belongs to the UPF0297 family
PIEKEEEF_00027	0.0	alaS	6.1.1.7		J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIEKEEEF_00028	8.9e-227	cshB	3.6.4.13		JKL	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIEKEEEF_00029	4.7e-182	nrnA	3.1.13.3, 3.1.3.7		S	DHHA1 domain protein
PIEKEEEF_00030	5.9e-216	dinB	2.7.7.7		L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIEKEEEF_00031	6.2e-287	zwf	1.1.1.363, 1.1.1.49		G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIEKEEEF_00032	9.6e-41	yajC			U	Preprotein translocase
PIEKEEEF_00033	1.5e-186	ruvB	3.6.4.12		L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIEKEEEF_00034	1.7e-102	ruvA	3.6.4.12		L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIEKEEEF_00035	0.0	mutL			L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIEKEEEF_00036	0.0	mutS			L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIEKEEEF_00037	2.6e-294	groL			O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIEKEEEF_00038	1.4e-41	groS			O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIEKEEEF_00039	4.6e-75
PIEKEEEF_00040	4e-181				M	CHAP domain
PIEKEEEF_00041	0.0	scrA	2.7.1.208, 2.7.1.211, 5.3.1.1		G	phosphotransferase system
PIEKEEEF_00042	2e-293	scrB	3.2.1.26	GH32	G	invertase
PIEKEEEF_00043	1e-184	scrR			K	helix_turn _helix lactose operon repressor
PIEKEEEF_00044	5.8e-112	rex			K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIEKEEEF_00045	0.0	uup			S	ABC transporter, ATP-binding protein
PIEKEEEF_00046	1e-154				L	COG2963 Transposase and inactivated derivatives
PIEKEEEF_00047	2e-194	tsaD	2.3.1.234		J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIEKEEEF_00048	7.4e-97	rimI	2.3.1.128		K	Ribosomal-protein-alanine acetyltransferase
PIEKEEEF_00049	4e-133	yeaZ	2.3.1.234		O	Universal bacterial protein YeaZ
PIEKEEEF_00050	2.4e-87				S	ECF transporter, substrate-specific component
PIEKEEEF_00051	1.5e-132	fat	3.1.2.21		I	Acyl-ACP thioesterase
PIEKEEEF_00052	7.9e-157	rsmI	2.1.1.198		H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIEKEEEF_00053	1.8e-59	yabA			L	Involved in initiation control of chromosome replication
PIEKEEEF_00054	1.7e-154	holB	2.7.7.7		L	DNA polymerase III
PIEKEEEF_00055	8.9e-53	yaaQ			S	Cyclic-di-AMP receptor
PIEKEEEF_00056	8.1e-114	tmk	2.7.4.9		F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIEKEEEF_00057	2.4e-34				S	Protein of unknown function (DUF2508)
PIEKEEEF_00058	2.1e-108	recR			L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIEKEEEF_00059	2.8e-41	yaaK			S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIEKEEEF_00060	2.4e-35				M	lipopolysaccharide 3-alpha-galactosyltransferase activity
PIEKEEEF_00061	0.0	dnaX	2.7.7.7		L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIEKEEEF_00062	2.2e-90	tadA	3.5.4.33		F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIEKEEEF_00063	9e-26
PIEKEEEF_00064	1.3e-116	rsmC	2.1.1.172		J	Methyltransferase
PIEKEEEF_00065	6e-141	potC	2.1.1.172, 2.1.1.80, 3.1.1.61		J	Ion channel
PIEKEEEF_00066	1.8e-54	rplL			J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIEKEEEF_00067	7e-84	rplJ			J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIEKEEEF_00068	7.8e-13			GT2,GT4	M	family 8
PIEKEEEF_00069	4.5e-136				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_00070	7.5e-118	phoU			P	Plays a role in the regulation of phosphate uptake
PIEKEEEF_00071	7.8e-140	pstB	3.6.3.27		P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIEKEEEF_00072	5e-145	pstB	3.6.3.27		P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIEKEEEF_00073	5.9e-155	pstA			P	Phosphate transport system permease protein PstA
PIEKEEEF_00074	3.9e-163	pstC			P	probably responsible for the translocation of the substrate across the membrane
PIEKEEEF_00075	1.4e-156	pstS			P	Phosphate
PIEKEEEF_00076	3.2e-124	rplA			J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIEKEEEF_00077	1.2e-68	rplK			J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIEKEEEF_00078	2e-100	nusG			K	Participates in transcription elongation, termination and antitermination
PIEKEEEF_00079	3.6e-24	secE			U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIEKEEEF_00080	0.0	dxs	2.2.1.7		H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIEKEEEF_00081	1.5e-288	gntK	2.7.1.12, 2.7.1.17		G	Belongs to the FGGY kinase family
PIEKEEEF_00082	1.7e-34
PIEKEEEF_00083	4.2e-95	sigH			K	Belongs to the sigma-70 factor family
PIEKEEEF_00084	6.6e-139	rlmB	2.1.1.185		J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIEKEEEF_00085	2.3e-75	mrnC			J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIEKEEEF_00086	4.4e-277	cysS	6.1.1.16, 6.3.1.13		J	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEKEEEF_00087	2.1e-290	gltX	6.1.1.17, 6.1.1.24		J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIEKEEEF_00088	2.7e-255	radA			O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIEKEEEF_00089	1.8e-101	dut	3.6.1.23, 4.1.1.36, 6.3.2.5		F	dUTP diphosphatase
PIEKEEEF_00090	6.4e-53
PIEKEEEF_00091	3e-267	pepC	3.4.22.40		E	Peptidase C1-like family
PIEKEEEF_00092	2.4e-183				S	AAA domain
PIEKEEEF_00093	1.2e-126	gpmA	5.4.2.11		G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIEKEEEF_00094	1.4e-23
PIEKEEEF_00095	1.1e-161	czcD			P	cation diffusion facilitator family transporter
PIEKEEEF_00096	7.5e-126	gpmB			G	Belongs to the phosphoglycerate mutase family
PIEKEEEF_00097	6.4e-134				S	membrane transporter protein
PIEKEEEF_00098	5.1e-119		3.1.3.18, 3.8.1.2		S	Haloacid dehalogenase-like hydrolase
PIEKEEEF_00099	7.4e-106	thiJ	2.7.11.1, 3.5.1.124		S	DJ-1/PfpI family
PIEKEEEF_00100	7e-80				K	Acetyltransferase (GNAT) domain
PIEKEEEF_00101	2.7e-147				M	Belongs to the glycosyl hydrolase 28 family
PIEKEEEF_00102	8.7e-66	rpsI			J	Belongs to the universal ribosomal protein uS9 family
PIEKEEEF_00103	5.9e-79	rplM			J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIEKEEEF_00104	3e-150	truA	5.4.99.12		J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIEKEEEF_00105	2.6e-138	ecfT			U	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEKEEEF_00106	2.1e-157	ecfA	3.6.3.55		P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEKEEEF_00107	1.4e-153	ecfA1			P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEKEEEF_00108	1.4e-60	rplQ			J	Ribosomal protein L17
PIEKEEEF_00109	1.1e-170	rpoA	2.7.7.6		K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEKEEEF_00110	3e-63	rpsK			J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIEKEEEF_00111	4.2e-56	rpsM			J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIEKEEEF_00112	7.8e-15	rpmJ			J	Belongs to the bacterial ribosomal protein bL36 family
PIEKEEEF_00113	8.4e-34	infA			J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIEKEEEF_00114	3.5e-120	adk	2.7.4.3		F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIEKEEEF_00115	1.4e-237	secY			U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIEKEEEF_00116	2.6e-71	rplO			J	Binds to the 23S rRNA
PIEKEEEF_00117	2.3e-24	rpmD			J	Ribosomal protein L30
PIEKEEEF_00118	4.1e-84	rpsE			J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIEKEEEF_00119	3.6e-55	rplR			J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIEKEEEF_00120	3.3e-92	rplF			J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIEKEEEF_00121	3.2e-68	rpsH			J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIEKEEEF_00122	8.9e-29	rpsN			J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIEKEEEF_00123	5.5e-95	rplE			J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIEKEEEF_00124	3.4e-33	rplX			J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIEKEEEF_00125	1.1e-59	rplN			J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIEKEEEF_00126	5e-41	rpsQ			J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIEKEEEF_00127	1.3e-25	rpmC			J	Belongs to the universal ribosomal protein uL29 family
PIEKEEEF_00128	2.1e-76	rplP			J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIEKEEEF_00129	2.7e-120	rpsC			J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIEKEEEF_00130	4e-54	rplV			J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIEKEEEF_00131	1.1e-46	rpsS			J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIEKEEEF_00132	7.3e-155	rplB			J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIEKEEEF_00133	3.1e-47	rplW			J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIEKEEEF_00134	2.1e-106	rplD			J	Forms part of the polypeptide exit tunnel
PIEKEEEF_00135	9e-113	rplC			J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIEKEEEF_00136	4.4e-49	rpsJ			J	Involved in the binding of tRNA to the ribosomes
PIEKEEEF_00137	0.0	fusA			J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIEKEEEF_00138	2.7e-82	rpsG			J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIEKEEEF_00139	7.8e-70	rpsL			J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIEKEEEF_00140	1.4e-119	pilD	3.4.23.43		NOU	Bacterial Peptidase A24 N-terminal domain
PIEKEEEF_00141	0.0	rpoC	2.7.7.6		K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEKEEEF_00142	0.0	rpoB	2.7.7.6		K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEKEEEF_00143	0.0	clpC			O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIEKEEEF_00144	2.5e-80	yebR	1.8.4.14		T	GAF domain-containing protein
PIEKEEEF_00146	1.6e-08
PIEKEEEF_00148	1.6e-08
PIEKEEEF_00149	3.4e-82				K	FR47-like protein
PIEKEEEF_00150	4.2e-297	lysS	6.1.1.6		J	Belongs to the class-II aminoacyl-tRNA synthetase family
PIEKEEEF_00151	6.7e-195	dus			J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIEKEEEF_00152	3.3e-166	hslO			O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIEKEEEF_00153	0.0	ftsH			O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIEKEEEF_00154	2.9e-240	tilS	2.4.2.8, 6.3.4.19		J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIEKEEEF_00155	6.3e-63	yabR			J	S1 RNA binding domain
PIEKEEEF_00156	6.8e-60	divIC			D	Septum formation initiator
PIEKEEEF_00157	1.6e-33	yabO			J	S4 domain protein
PIEKEEEF_00158	0.0	mfd			L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIEKEEEF_00159	1e-104	pth	3.1.1.29		J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIEKEEEF_00160	4e-181	ldh	1.1.1.27		C	Belongs to the LDH MDH superfamily. LDH family
PIEKEEEF_00161	3.4e-129				S	(CBS) domain
PIEKEEEF_00162	8.4e-215	alr	5.1.1.1		E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIEKEEEF_00163	1.7e-60	acpS	2.7.6.3, 2.7.8.7, 5.1.1.1		I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIEKEEEF_00164	5.4e-246	cshA	3.6.4.13		F	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIEKEEEF_00165	1.3e-262	murF	6.3.2.10, 6.3.2.13		M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIEKEEEF_00166	2.5e-39	rpmE2			J	Ribosomal protein L31
PIEKEEEF_00167	0.0	dexB	3.2.1.10, 3.2.1.70	GH13	G	Alpha amylase, catalytic domain protein
PIEKEEEF_00168	2.2e-156				S	Sucrose-6F-phosphate phosphohydrolase
PIEKEEEF_00169	1.9e-297	ybeC			E	amino acid
PIEKEEEF_00170	2.2e-232	glyA	2.1.2.1		E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIEKEEEF_00171	4.7e-42
PIEKEEEF_00172	2.4e-51
PIEKEEEF_00173	8.9e-184		5.3.3.2		C	FMN-dependent dehydrogenase
PIEKEEEF_00174	2.8e-144	yfeO			P	Voltage gated chloride channel
PIEKEEEF_00175	1e-95
PIEKEEEF_00176	9.4e-97	ogt	2.1.1.63, 3.2.2.20		L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIEKEEEF_00177	1.1e-18	yjdF			S	Protein of unknown function (DUF2992)
PIEKEEEF_00178	7.9e-57	ps115			K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_00181	0.0		3.2.1.18	GH33	M	Rib/alpha-like repeat
PIEKEEEF_00182	3.3e-46				L	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PIEKEEEF_00183	1.6e-304	guaA	2.3.1.128, 6.3.5.2		F	Catalyzes the synthesis of GMP from XMP
PIEKEEEF_00184	7.8e-37				K	Helix-turn-helix
PIEKEEEF_00185	1.1e-104	xpt	2.4.2.22, 2.4.2.7		F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIEKEEEF_00186	2.2e-227	pbuX			F	xanthine permease
PIEKEEEF_00187	8.4e-251				L	Putative transposase DNA-binding domain
PIEKEEEF_00188	4.9e-116				L	Resolvase, N-terminal
PIEKEEEF_00189	1.6e-154	msmR			K	AraC-like ligand binding domain
PIEKEEEF_00190	4.4e-285	pipD			E	Dipeptidase
PIEKEEEF_00191	1.3e-47	adk	2.7.4.3		F	AAA domain
PIEKEEEF_00192	1.4e-79				K	acetyltransferase
PIEKEEEF_00193	4e-245	murA	2.5.1.7		M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIEKEEEF_00194	6.7e-311	pyrG	6.3.4.2		F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIEKEEEF_00195	1.7e-46	rpoE			K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIEKEEEF_00196	5.9e-68				S	Domain of unknown function (DUF1934)
PIEKEEEF_00197	1.9e-269	ywfO			S	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEKEEEF_00198	1.7e-44
PIEKEEEF_00199	4.2e-172		2.7.1.2		GK	ROK family
PIEKEEEF_00200	6.7e-176	prs	2.7.6.1		F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIEKEEEF_00201	0.0				S	SLAP domain
PIEKEEEF_00202	5.3e-80
PIEKEEEF_00203	2.6e-173	glmU	2.3.1.157, 2.7.7.23		M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIEKEEEF_00204	3.8e-148	purR	2.4.2.22, 2.4.2.7		F	pur operon repressor
PIEKEEEF_00205	4.5e-39	veg			S	Biofilm formation stimulator VEG
PIEKEEEF_00206	3e-159	ksgA	2.1.1.182		J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIEKEEEF_00207	1e-99	rnmV	3.1.26.8		J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIEKEEEF_00208	2.5e-146	tatD			L	hydrolase, TatD family
PIEKEEEF_00209	0.0	metG	6.1.1.10		J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIEKEEEF_00210	0.0	mgtA	3.6.3.2		P	COG0474 Cation transport ATPase
PIEKEEEF_00211	2.2e-102				S	TPM domain
PIEKEEEF_00212	6.1e-90	comEB	3.5.4.12		F	MafB19-like deaminase
PIEKEEEF_00213	1.1e-192	trpS	6.1.1.2		J	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEKEEEF_00214	1.2e-111				E	Belongs to the SOS response-associated peptidase family
PIEKEEEF_00216	1.2e-112
PIEKEEEF_00217	2.6e-77	greA			K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIEKEEEF_00218	8.4e-67	hsp			O	Belongs to the small heat shock protein (HSP20) family
PIEKEEEF_00219	2e-255	pepC	3.4.22.40		E	aminopeptidase
PIEKEEEF_00220	1.9e-175	oppF			P	Belongs to the ABC transporter superfamily
PIEKEEEF_00221	4.7e-199	oppD			P	Belongs to the ABC transporter superfamily
PIEKEEEF_00222	8e-188	oppC			EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIEKEEEF_00223	2.4e-146	oppB			P	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIEKEEEF_00224	1.7e-210	guaB	1.1.1.205		F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIEKEEEF_00225	4.5e-310	oppA			E	ABC transporter, substratebinding protein
PIEKEEEF_00226	1.7e-301	oppA			E	ABC transporter, substratebinding protein
PIEKEEEF_00227	7e-121	ypgQ			S	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEKEEEF_00228	1.6e-257	pepC	3.4.22.40		E	aminopeptidase
PIEKEEEF_00230	4.5e-53
PIEKEEEF_00231	3.7e-243	tyrS	6.1.1.1		J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIEKEEEF_00232	4.5e-266				S	Fibronectin type III domain
PIEKEEEF_00233	0.0	XK27_08315			M	Sulfatase
PIEKEEEF_00234	5.6e-112	plsY	2.3.1.15		I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIEKEEEF_00235	2.6e-200	brpA			K	Cell envelope-like function transcriptional attenuator common domain protein
PIEKEEEF_00236	5.5e-98				G	Aldose 1-epimerase
PIEKEEEF_00237	5e-133	gpmA	5.4.2.11		G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIEKEEEF_00238	2.1e-116
PIEKEEEF_00239	1.2e-130
PIEKEEEF_00240	1.3e-160				S	Oxidoreductase family, NAD-binding Rossmann fold
PIEKEEEF_00241	1.7e-106	pcp	3.4.19.3		O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIEKEEEF_00242	0.0	yjbQ			P	TrkA C-terminal domain protein
PIEKEEEF_00243	7.2e-179	atl	3.2.1.96, 3.5.1.28	GH73	M	N-acetylmuramoyl-L-alanine amidase
PIEKEEEF_00244	2.4e-215				NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIEKEEEF_00246	8.1e-109				S	SLAP domain
PIEKEEEF_00247	4.9e-143		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_00248	3e-26
PIEKEEEF_00249	9.4e-78				K	DNA-templated transcription, initiation
PIEKEEEF_00251	4.5e-43
PIEKEEEF_00253	2.2e-35
PIEKEEEF_00254	2.8e-100				S	SLAP domain
PIEKEEEF_00255	3.3e-40				S	Protein of unknown function (DUF2922)
PIEKEEEF_00256	5.5e-30
PIEKEEEF_00258	4.5e-45
PIEKEEEF_00259	7.5e-59				T	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIEKEEEF_00260	1.6e-67		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_00261	3.3e-74
PIEKEEEF_00262	0.0	kup			P	Transport of potassium into the cell
PIEKEEEF_00263	0.0	pepO	3.4.24.71		O	Peptidase family M13
PIEKEEEF_00264	3.6e-211	yttB			EGP	Major facilitator Superfamily
PIEKEEEF_00265	3.4e-230	XK27_04775			S	PAS domain
PIEKEEEF_00266	2.1e-103				S	Iron-sulfur cluster assembly protein
PIEKEEEF_00267	8.7e-141	nrdG	1.97.1.4		O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIEKEEEF_00268	0.0	nrdD	1.1.98.6		F	Ribonucleoside-triphosphate reductase
PIEKEEEF_00269	5.6e-255	yxbA	6.3.1.12		S	ATP-grasp enzyme
PIEKEEEF_00270	0.0	asnB	6.3.5.4		E	Asparagine synthase
PIEKEEEF_00271	3.4e-274				S	Calcineurin-like phosphoesterase
PIEKEEEF_00272	8.7e-84
PIEKEEEF_00273	5.5e-106	tag	3.2.2.20		L	glycosylase
PIEKEEEF_00274	2.2e-148	phnE	3.6.1.63		P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_00275	4.3e-112	phnE	3.6.1.63		P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_00276	4.1e-136	phnC	3.6.3.28		P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PIEKEEEF_00277	4.1e-151	phnD			P	Phosphonate ABC transporter
PIEKEEEF_00278	1.5e-83	uspA			T	universal stress protein
PIEKEEEF_00279	2.6e-149	ptp3	3.1.3.48		T	Tyrosine phosphatase family
PIEKEEEF_00280	8.6e-87		2.7.1.200, 2.7.1.202, 2.7.1.204		G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIEKEEEF_00281	3.6e-90	ntd	2.4.2.6		F	Nucleoside
PIEKEEEF_00282	1.9e-272				S	Archaea bacterial proteins of unknown function
PIEKEEEF_00283	3.5e-216	nagA	3.5.1.25		G	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIEKEEEF_00284	0.0				G	Belongs to the glycosyl hydrolase 31 family
PIEKEEEF_00285	8.6e-148				I	alpha/beta hydrolase fold
PIEKEEEF_00286	3.8e-129	yibF			S	overlaps another CDS with the same product name
PIEKEEEF_00287	2.2e-202	yibE			S	overlaps another CDS with the same product name
PIEKEEEF_00288	1.4e-112
PIEKEEEF_00289	1.2e-205	ddl	6.3.2.4		F	Belongs to the D-alanine--D-alanine ligase family
PIEKEEEF_00290	1.4e-223				S	Cysteine-rich secretory protein family
PIEKEEEF_00291	1.2e-132	glnQ	3.6.3.21		E	ABC transporter, ATP-binding protein
PIEKEEEF_00292	1.4e-257	glnPH2			P	ABC transporter permease
PIEKEEEF_00293	2.8e-135
PIEKEEEF_00294	2.7e-123	luxT			K	Bacterial regulatory proteins, tetR family
PIEKEEEF_00295	1.8e-181	prs	2.7.6.1		F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIEKEEEF_00296	9.2e-14				S	Helix-turn-helix domain
PIEKEEEF_00297	1.4e-26				E	Zn peptidase
PIEKEEEF_00298	5.8e-85		2.3.1.128		K	Acetyltransferase (GNAT) domain
PIEKEEEF_00299	2.4e-94				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_00300	4.1e-207				V	ABC transporter transmembrane region
PIEKEEEF_00301	5.7e-47
PIEKEEEF_00302	4.9e-159				S	reductase
PIEKEEEF_00303	2e-29
PIEKEEEF_00304	1.9e-286				K	Putative DNA-binding domain
PIEKEEEF_00305	3.8e-238	pyrP			F	Permease
PIEKEEEF_00306	1.8e-90	pyrR	2.4.2.9		F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIEKEEEF_00307	7.8e-261	emrY			EGP	Major facilitator Superfamily
PIEKEEEF_00308	4.3e-217	mdtG			EGP	Major facilitator Superfamily
PIEKEEEF_00309	2.4e-136
PIEKEEEF_00310	4.2e-101
PIEKEEEF_00311	1.7e-209	pepA			E	M42 glutamyl aminopeptidase
PIEKEEEF_00312	2.2e-311	ybiT			S	ABC transporter, ATP-binding protein
PIEKEEEF_00313	5.9e-174				S	Aldo keto reductase
PIEKEEEF_00314	1.2e-61
PIEKEEEF_00315	4e-62
PIEKEEEF_00316	8e-241	steT			E	amino acid
PIEKEEEF_00317	3e-243	steT			E	amino acid
PIEKEEEF_00318	4.9e-130	yfeJ	6.3.5.2		F	glutamine amidotransferase
PIEKEEEF_00319	6.4e-148	glnH			ET	ABC transporter
PIEKEEEF_00320	1.4e-80				K	Transcriptional regulator, MarR family
PIEKEEEF_00321	1.1e-309	XK27_09600			V	ABC transporter, ATP-binding protein
PIEKEEEF_00322	0.0				V	ABC transporter transmembrane region
PIEKEEEF_00323	3.8e-102				S	ABC-type cobalt transport system, permease component
PIEKEEEF_00324	7.4e-253				G	MFS/sugar transport protein
PIEKEEEF_00325	3.6e-114	udk	2.7.1.48		F	Zeta toxin
PIEKEEEF_00326	1.9e-135	glnQ	3.6.3.21		E	ABC transporter, ATP-binding protein
PIEKEEEF_00327	1.5e-149	glnH			ET	ABC transporter substrate-binding protein
PIEKEEEF_00328	9.7e-91	gluC			P	ABC transporter permease
PIEKEEEF_00329	4.7e-109	glnP			P	ABC transporter permease
PIEKEEEF_00330	1.1e-164				S	Protein of unknown function (DUF2974)
PIEKEEEF_00331	3.6e-85
PIEKEEEF_00332	5e-209				S	Uncharacterized protein conserved in bacteria (DUF2325)
PIEKEEEF_00333	2.3e-232				G	Bacterial extracellular solute-binding protein
PIEKEEEF_00334	7.7e-162		2.7.7.12		C	Domain of unknown function (DUF4931)
PIEKEEEF_00335	1.2e-166	rbsK	2.7.1.15		H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIEKEEEF_00336	9e-127	rpiA	2.7.1.12, 2.7.1.15, 5.3.1.6		G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIEKEEEF_00337	0.0	kup			P	Transport of potassium into the cell
PIEKEEEF_00338	2.7e-174	rihB	3.2.2.1		F	Nucleoside
PIEKEEEF_00339	2.8e-134	ydhQ			K	UbiC transcription regulator-associated domain protein
PIEKEEEF_00340	1.2e-154				S	hydrolase
PIEKEEEF_00341	2.5e-59				S	Enterocin A Immunity
PIEKEEEF_00342	1.5e-135	glcR			K	DeoR C terminal sensor domain
PIEKEEEF_00343	0.0	xfp	4.1.2.22, 4.1.2.9		G	Phosphoketolase
PIEKEEEF_00344	6.9e-161	rssA			S	Phospholipase, patatin family
PIEKEEEF_00345	6.3e-148				S	hydrolase
PIEKEEEF_00346	0.0	glvC	2.7.1.199, 2.7.1.208, 2.7.1.211		G	phosphotransferase system, EIIB
PIEKEEEF_00347	4.1e-147	glvR			K	Helix-turn-helix domain, rpiR family
PIEKEEEF_00348	2.7e-80
PIEKEEEF_00349	3.2e-86	pts23A			G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PIEKEEEF_00350	2.1e-39
PIEKEEEF_00351	3.9e-119				C	nitroreductase
PIEKEEEF_00352	2.8e-249	yhdP			S	Transporter associated domain
PIEKEEEF_00353	3.4e-103	hpt	2.4.2.8		F	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIEKEEEF_00354	0.0		1.3.5.4		C	FAD binding domain
PIEKEEEF_00355	2.9e-88				L	PFAM transposase, IS4 family protein
PIEKEEEF_00356	1.2e-49				L	PFAM transposase, IS4 family protein
PIEKEEEF_00357	0.0		1.3.5.4		C	FAD binding domain
PIEKEEEF_00358	2.8e-230	potE			E	amino acid
PIEKEEEF_00359	4.7e-131				M	Glycosyl hydrolases family 25
PIEKEEEF_00360	1.4e-210	yfmL	3.6.4.13		L	DEAD DEAH box helicase
PIEKEEEF_00361	1.8e-248	celB			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00363	2e-216	mnaA	5.1.3.14		G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIEKEEEF_00364	5.8e-201				L	Transposase DDE domain
PIEKEEEF_00365	3.1e-87	gtcA			S	Teichoic acid glycosylation protein
PIEKEEEF_00366	4.1e-80	fld			C	Flavodoxin
PIEKEEEF_00367	6.5e-164	map	3.4.11.18		E	Methionine Aminopeptidase
PIEKEEEF_00368	1.4e-162	yihY			S	Belongs to the UPF0761 family
PIEKEEEF_00369	7.3e-169	galU	2.7.7.9		M	UTP-glucose-1-phosphate uridylyltransferase
PIEKEEEF_00370	2.3e-215	atoB	1.1.1.88, 2.3.1.9		I	Belongs to the thiolase family
PIEKEEEF_00371	7.9e-211	mvaA	1.1.1.34, 1.1.1.88, 2.3.1.9		C	Belongs to the HMG-CoA reductase family
PIEKEEEF_00372	1.9e-217	mvaS	2.3.3.10		I	Hydroxymethylglutaryl-CoA synthase
PIEKEEEF_00373	2.7e-45
PIEKEEEF_00374	8.9e-178				D	Alpha beta
PIEKEEEF_00375	5.4e-264	rumA	2.1.1.190, 2.1.1.35		J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIEKEEEF_00376	3.3e-144	recX	2.4.1.337	GT4	S	Regulatory protein RecX
PIEKEEEF_00377	6e-85
PIEKEEEF_00378	1.6e-74
PIEKEEEF_00379	4e-140	hlyX			S	Transporter associated domain
PIEKEEEF_00380	1.2e-304	prfC			J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIEKEEEF_00381	2.3e-44	XK27_09445			S	Domain of unknown function (DUF1827)
PIEKEEEF_00382	0.0	clpE			O	Belongs to the ClpA ClpB family
PIEKEEEF_00383	5.3e-26
PIEKEEEF_00384	8.5e-41	ptsH			G	phosphocarrier protein HPR
PIEKEEEF_00385	0.0	ptsI	2.7.3.9		G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIEKEEEF_00386	3.9e-66	spxA	1.20.4.1		K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIEKEEEF_00387	8.5e-139	mecA			NOT	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIEKEEEF_00388	1.7e-159	coiA	3.6.4.12		S	Competence protein
PIEKEEEF_00389	4.6e-114	yjbH			Q	Thioredoxin
PIEKEEEF_00390	1.2e-109	yjbK			S	CYTH
PIEKEEEF_00391	1.2e-114	yjbM	2.7.6.5		S	RelA SpoT domain protein
PIEKEEEF_00392	3.8e-153	nadK	2.7.1.23		F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIEKEEEF_00393	6.4e-173	rluD	5.4.99.23		J	Responsible for synthesis of pseudouridine from uracil
PIEKEEEF_00394	0.0	mycA	4.2.1.53		S	Myosin-crossreactive antigen
PIEKEEEF_00395	4.2e-92				S	SNARE associated Golgi protein
PIEKEEEF_00396	1.4e-200	pgl	3.1.1.31		G	Lactonase, 7-bladed beta-propeller
PIEKEEEF_00397	7.1e-65	srlB	2.7.1.198		G	PTS system glucitol/sorbitol-specific IIA component
PIEKEEEF_00398	2.6e-214	yubA			S	AI-2E family transporter
PIEKEEEF_00399	4.2e-106	trmL	2.1.1.207		J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIEKEEEF_00400	1.7e-69	WQ51_03320			S	Protein of unknown function (DUF1149)
PIEKEEEF_00401	0.0	ftsK			D	Belongs to the FtsK SpoIIIE SftA family
PIEKEEEF_00402	2.9e-221		2.7.1.26, 2.7.7.2		S	Peptidase M16 inactive domain protein
PIEKEEEF_00403	7.3e-236				S	Peptidase M16
PIEKEEEF_00404	5.8e-132				IQ	Enoyl-(Acyl carrier protein) reductase
PIEKEEEF_00405	2.6e-96	ymfM			S	Helix-turn-helix domain
PIEKEEEF_00406	3.3e-95	pgsA	2.7.8.41, 2.7.8.5		I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIEKEEEF_00407	8.5e-196	recA			L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIEKEEEF_00408	4.3e-220	rny			S	Endoribonuclease that initiates mRNA decay
PIEKEEEF_00409	1.3e-210	tagO	2.7.8.33, 2.7.8.35		M	transferase
PIEKEEEF_00410	5.1e-119	yvyE	3.4.13.9		S	YigZ family
PIEKEEEF_00411	1.4e-245	comFA			L	Helicase C-terminal domain protein
PIEKEEEF_00412	9.4e-132	comFC			S	Competence protein
PIEKEEEF_00413	1.6e-94	hpf			J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIEKEEEF_00414	0.0	secA			U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIEKEEEF_00415	4.6e-188	prfB			J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIEKEEEF_00416	5.1e-17
PIEKEEEF_00417	5.8e-180	hprK			F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIEKEEEF_00418	1.1e-158	lgt	2.1.1.199		M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIEKEEEF_00419	5.7e-186	gpsA	1.1.1.94		I	Glycerol-3-phosphate dehydrogenase
PIEKEEEF_00420	3.9e-181	trxB	1.8.1.9		C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIEKEEEF_00421	0.0	pgm	5.4.2.2, 5.4.2.8		G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PIEKEEEF_00422	0.0	uvrB			L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIEKEEEF_00423	0.0	uvrA			L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIEKEEEF_00424	1.1e-90				S	Short repeat of unknown function (DUF308)
PIEKEEEF_00425	6.2e-165	rapZ			S	Displays ATPase and GTPase activities
PIEKEEEF_00426	3.4e-194	ybhK			S	Required for morphogenesis under gluconeogenic growth conditions
PIEKEEEF_00427	2.1e-171	whiA			K	May be required for sporulation
PIEKEEEF_00428	6.7e-99	clpP	3.4.21.92		O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIEKEEEF_00429	0.0				S	SH3-like domain
PIEKEEEF_00430	4.9e-111	ybbL			S	ABC transporter, ATP-binding protein
PIEKEEEF_00431	2.5e-130	ybbM			S	Uncharacterised protein family (UPF0014)
PIEKEEEF_00432	1.4e-93				S	Domain of unknown function (DUF4811)
PIEKEEEF_00433	7e-262	lmrB			EGP	Major facilitator Superfamily
PIEKEEEF_00434	5.4e-77				K	MerR HTH family regulatory protein
PIEKEEEF_00435	8.6e-142				S	Cysteine-rich secretory protein family
PIEKEEEF_00436	4.6e-274	ycaM			E	amino acid
PIEKEEEF_00437	1.6e-288
PIEKEEEF_00439	7.4e-189	cggR			K	Putative sugar-binding domain
PIEKEEEF_00440	6.5e-190	gap	1.2.1.12		G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIEKEEEF_00441	1e-226	pgk	2.7.2.3, 5.3.1.1		F	Belongs to the phosphoglycerate kinase family
PIEKEEEF_00442	1.7e-142	tpiA	2.7.2.3, 5.3.1.1		G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIEKEEEF_00443	1.2e-94
PIEKEEEF_00444	1.4e-156	ycsE			S	Sucrose-6F-phosphate phosphohydrolase
PIEKEEEF_00445	9.7e-137	ung	3.2.2.27		L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIEKEEEF_00446	6.3e-182	pta	2.3.1.8, 3.6.3.21		C	phosphate acetyltransferase
PIEKEEEF_00447	1.4e-86	ydiB	2.7.1.221, 5.1.1.1		O	Hydrolase, P-loop family
PIEKEEEF_00448	4e-98	dnaQ	2.7.7.7		L	DNA polymerase III
PIEKEEEF_00449	1.8e-164	murB	1.3.1.98		M	Cell wall formation
PIEKEEEF_00450	1.8e-206	potA	3.6.3.30, 3.6.3.31		P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIEKEEEF_00451	5.4e-131	potB			P	ABC transporter permease
PIEKEEEF_00452	4.8e-127	potC			P	ABC transporter permease
PIEKEEEF_00453	7.3e-208	potD			P	ABC transporter
PIEKEEEF_00454	6.4e-151	dacA	2.7.7.85		S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIEKEEEF_00455	2e-172	ybbR			S	YbbR-like protein
PIEKEEEF_00456	3.1e-256	glmM	5.4.2.10		G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIEKEEEF_00457	2.4e-147				S	hydrolase
PIEKEEEF_00458	8.7e-75				K	Penicillinase repressor
PIEKEEEF_00459	2.5e-119
PIEKEEEF_00460	8.1e-84	ptpA	3.1.3.48		T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIEKEEEF_00461	1.4e-209	glxK	2.7.1.165		G	Belongs to the glycerate kinase type-1 family
PIEKEEEF_00462	5.4e-142	licT			K	CAT RNA binding domain
PIEKEEEF_00463	0.0	bglP	2.7.1.208, 2.7.1.211		G	phosphotransferase system
PIEKEEEF_00464	2.6e-296		3.2.1.86	GT1	G	Belongs to the glycosyl hydrolase 1 family
PIEKEEEF_00465	2.3e-149				D	Alpha beta
PIEKEEEF_00466	1.2e-92	yhjH	3.1.4.52		T	Putative diguanylate phosphodiesterase
PIEKEEEF_00467	4.8e-26	queD	4.1.2.50, 4.2.3.12		H	6-pyruvoyl tetrahydropterin synthase
PIEKEEEF_00468	3.9e-118	ica2		GT2	M	Glycosyl transferase family group 2
PIEKEEEF_00469	8.2e-36
PIEKEEEF_00470	2.8e-90		2.7.7.65		T	GGDEF domain
PIEKEEEF_00471	2.6e-81				M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PIEKEEEF_00473	9e-311				E	Amino acid permease
PIEKEEEF_00475	9.8e-28	rpsN			J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIEKEEEF_00476	3.2e-110	ylbE			GM	NAD(P)H-binding
PIEKEEEF_00477	4.2e-92				S	VanZ like family
PIEKEEEF_00478	8.9e-133	yebC			K	Transcriptional regulatory protein
PIEKEEEF_00479	4.9e-179	comGA			NU	Type II IV secretion system protein
PIEKEEEF_00480	2.7e-172	comGB			NU	type II secretion system
PIEKEEEF_00481	3.1e-43	comGC			U	competence protein ComGC
PIEKEEEF_00482	2.1e-70
PIEKEEEF_00483	2.3e-41
PIEKEEEF_00484	3.8e-77	comGF			U	Putative Competence protein ComGF
PIEKEEEF_00485	1.6e-21
PIEKEEEF_00486	8.6e-187	ytxK	2.1.1.72		L	N-6 DNA Methylase
PIEKEEEF_00487	1.4e-220	ackA	2.7.2.1		F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIEKEEEF_00489	4.1e-16				M	Protein of unknown function (DUF3737)
PIEKEEEF_00490	2.4e-79				M	Protein of unknown function (DUF3737)
PIEKEEEF_00491	4.6e-224	patB	4.4.1.8		E	Aminotransferase, class I
PIEKEEEF_00492	1.6e-190	manA	5.3.1.8		G	mannose-6-phosphate isomerase
PIEKEEEF_00493	7.7e-67				S	SdpI/YhfL protein family
PIEKEEEF_00494	1.7e-128				K	Transcriptional regulatory protein, C terminal
PIEKEEEF_00495	3.6e-266	yclK	2.7.13.3, 4.6.1.1		T	Histidine kinase
PIEKEEEF_00496	0.0	ltaS	2.7.8.20		M	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIEKEEEF_00497	1.1e-104	vanZ			V	VanZ like family
PIEKEEEF_00498	3.2e-253	pgi	5.3.1.9		G	Belongs to the GPI family
PIEKEEEF_00499	4.2e-216				EGP	Major facilitator Superfamily
PIEKEEEF_00500	1.1e-194	ampC			V	Beta-lactamase
PIEKEEEF_00503	1.7e-262	murF	6.3.2.10, 6.3.2.13		M	Domain of unknown function (DUF1727)
PIEKEEEF_00504	1.3e-113	tdk	2.7.1.21		F	thymidine kinase
PIEKEEEF_00505	2.6e-181	prfA			J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIEKEEEF_00506	1.3e-154	prmB	2.1.1.297, 2.1.1.298		J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIEKEEEF_00507	3.7e-190	ywlC	2.7.7.87, 3.1.3.48		J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIEKEEEF_00508	6.8e-113	upp	2.4.2.9		F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIEKEEEF_00509	1e-128	atpB			C	it plays a direct role in the translocation of protons across the membrane
PIEKEEEF_00510	3.5e-27	atpE			C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIEKEEEF_00511	3.4e-46	atpF			C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIEKEEEF_00512	2e-92	atpH			C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIEKEEEF_00513	2.5e-283	atpA	3.6.3.14		C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIEKEEEF_00514	8.9e-173	atpG			C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIEKEEEF_00515	3.7e-239	atpD	3.6.3.14		C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIEKEEEF_00516	7.6e-71	atpC			C	Produces ATP from ADP in the presence of a proton gradient across the membrane
PIEKEEEF_00517	3.4e-30	ywzB			S	Protein of unknown function (DUF1146)
PIEKEEEF_00518	2.5e-178	mbl			D	Cell shape determining protein MreB Mrl
PIEKEEEF_00519	2e-51	yidD			S	Could be involved in insertion of integral membrane proteins into the membrane
PIEKEEEF_00520	1.5e-33				S	Protein of unknown function (DUF2969)
PIEKEEEF_00521	1.2e-216	rodA			D	Belongs to the SEDS family
PIEKEEEF_00522	1.9e-158	tuf			J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIEKEEEF_00523	3.4e-215	tig			D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIEKEEEF_00524	2e-233	clpX			O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIEKEEEF_00525	1.1e-104	engB			D	Necessary for normal cell division and for the maintenance of normal septation
PIEKEEEF_00526	7.8e-39	yjeM			E	Amino Acid
PIEKEEEF_00527	2.6e-178	yjeM			E	Amino Acid
PIEKEEEF_00528	2.3e-192	dapF	5.1.1.7		E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIEKEEEF_00529	3e-259	lysC	2.7.2.4		E	Belongs to the aspartokinase family
PIEKEEEF_00530	7.4e-247	lysA	4.1.1.19, 4.1.1.20		E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIEKEEEF_00531	2.8e-75	dapD	2.3.1.117, 2.3.1.89		E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIEKEEEF_00532	1.1e-220	hipO	3.5.1.47		E	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIEKEEEF_00533	9.8e-177	dapA	4.3.3.7		E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIEKEEEF_00534	7e-144	dapB	1.17.1.8		E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIEKEEEF_00535	9.4e-217	aspC	2.6.1.1		E	Aminotransferase
PIEKEEEF_00536	2.3e-198	asd	1.2.1.11		E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIEKEEEF_00537	1.6e-194	pbpX1			V	Beta-lactamase
PIEKEEEF_00538	7.9e-299				I	Protein of unknown function (DUF2974)
PIEKEEEF_00539	3.6e-39				C	FMN_bind
PIEKEEEF_00540	2.5e-81
PIEKEEEF_00541	1.4e-175	iunH	3.2.2.1		F	inosine-uridine preferring nucleoside hydrolase
PIEKEEEF_00542	4.4e-57	alkD			L	DNA alkylation repair enzyme
PIEKEEEF_00543	8.9e-294	celA	3.2.1.86	GT1	G	Belongs to the glycosyl hydrolase 1 family
PIEKEEEF_00544	3.7e-128				K	UTRA domain
PIEKEEEF_00545	1.6e-55	celA1	2.7.1.196, 2.7.1.205		G	PTS system, Lactose/Cellobiose specific IIB subunit
PIEKEEEF_00546	8.7e-60	chbA	2.7.1.196, 2.7.1.205		G	PTS system, Lactose Cellobiose specific IIA subunit
PIEKEEEF_00547	2.8e-85
PIEKEEEF_00548	7.4e-250	celD			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00549	3.2e-71				S	Domain of unknown function (DUF3284)
PIEKEEEF_00550	1.3e-300		3.2.1.86	GT1	G	Belongs to the glycosyl hydrolase 1 family
PIEKEEEF_00551	1.5e-119	gmuR			K	UTRA
PIEKEEEF_00552	3.7e-223	pts23C			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00553	4.4e-274	bglA3	3.2.1.86	GT1	G	Belongs to the glycosyl hydrolase 1 family
PIEKEEEF_00554	7.1e-137	ypbG	2.7.1.2		GK	ROK family
PIEKEEEF_00555	1.2e-85				C	nitroreductase
PIEKEEEF_00556	1.3e-90				S	Domain of unknown function (DUF4767)
PIEKEEEF_00557	1.5e-244	eno	4.2.1.11		G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIEKEEEF_00558	2.5e-147	yitS			S	Uncharacterised protein, DegV family COG1307
PIEKEEEF_00559	2.2e-102		3.6.1.27		I	Acid phosphatase homologues
PIEKEEEF_00560	2.4e-189	cbh	3.5.1.24		M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIEKEEEF_00562	2e-178	MA20_14895			S	Conserved hypothetical protein 698
PIEKEEEF_00563	1.3e-84	dps			P	Belongs to the Dps family
PIEKEEEF_00564	1.1e-14				K	Acetyltransferase (GNAT) domain
PIEKEEEF_00565	1.5e-14		1.3.5.4		C	succinate dehydrogenase
PIEKEEEF_00566	9.6e-13
PIEKEEEF_00567	6.9e-99	yihX	3.1.3.10, 3.8.1.2		S	Haloacid dehalogenase-like hydrolase
PIEKEEEF_00568	9.9e-71				S	Putative adhesin
PIEKEEEF_00569	1.7e-78	yjaB	2.3.1.181		K	Acetyltransferase (GNAT) domain
PIEKEEEF_00570	5.1e-235	mepA			V	MATE efflux family protein
PIEKEEEF_00571	4.9e-25				M	Peptidase family M1 domain
PIEKEEEF_00572	3e-27				M	Peptidase family M1 domain
PIEKEEEF_00573	2.1e-149
PIEKEEEF_00575	9.7e-247	ydaM			M	Glycosyl transferase
PIEKEEEF_00576	2.6e-205				G	Glycosyl hydrolases family 8
PIEKEEEF_00577	8.2e-68				L	Transposase and inactivated derivatives, IS30 family
PIEKEEEF_00578	2.2e-14				L	Transposase and inactivated derivatives, IS30 family
PIEKEEEF_00579	1.7e-12				L	Transposase and inactivated derivatives, IS30 family
PIEKEEEF_00580	2.4e-10				L	Psort location Cytoplasmic, score
PIEKEEEF_00581	4e-89				L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PIEKEEEF_00582	1.9e-80	ribH	2.5.1.78		H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PIEKEEEF_00583	6.3e-229	ribBA	3.5.4.25, 4.1.99.12		H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PIEKEEEF_00584	4e-107	ribE	2.5.1.9, 3.5.4.25, 4.1.99.12		H	Riboflavin synthase
PIEKEEEF_00585	1.6e-199	ribD	1.1.1.193, 3.5.4.26		H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PIEKEEEF_00586	2e-118	lsa			S	ABC transporter
PIEKEEEF_00587	2.8e-112				S	Protein of unknown function (DUF1211)
PIEKEEEF_00588	3.5e-107	ltrA			S	Bacterial low temperature requirement A protein (LtrA)
PIEKEEEF_00589	2.8e-119		3.6.1.55		F	NUDIX domain
PIEKEEEF_00590	8.6e-246	brnQ			U	Component of the transport system for branched-chain amino acids
PIEKEEEF_00591	1.3e-11				L	Plasmid pRiA4b ORF-3-like protein
PIEKEEEF_00592	3.7e-271				L	Plasmid pRiA4b ORF-3-like protein
PIEKEEEF_00593	1.3e-87	tpx	1.11.1.15		O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIEKEEEF_00594	2.5e-08				S	Protein of unknown function (DUF3021)
PIEKEEEF_00595	5.9e-33				K	Bacterial regulatory helix-turn-helix protein, lysR family
PIEKEEEF_00596	3.2e-34	rmaI			K	Transcriptional regulator
PIEKEEEF_00597	1.4e-131	lmrB			EGP	Major facilitator Superfamily
PIEKEEEF_00598	4.7e-36	rbtT			P	Major Facilitator Superfamily
PIEKEEEF_00599	2e-41	XK27_00915			C	Luciferase-like monooxygenase
PIEKEEEF_00600	3.7e-142	XK27_00915			C	Luciferase-like monooxygenase
PIEKEEEF_00601	2.5e-86				K	GNAT family
PIEKEEEF_00602	1.4e-124				S	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PIEKEEEF_00604	1.5e-36
PIEKEEEF_00605	7.3e-289				P	ABC transporter
PIEKEEEF_00606	1.2e-286				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_00607	9e-251	yifK			E	Amino acid permease
PIEKEEEF_00608	1.3e-179	thyA	2.1.1.45		F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIEKEEEF_00609	1.5e-91	folA	1.5.1.3		H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIEKEEEF_00610	0.0	aha1			P	E1-E2 ATPase
PIEKEEEF_00611	4.2e-175				F	DNA/RNA non-specific endonuclease
PIEKEEEF_00612	5.9e-160	metQ2			P	Belongs to the nlpA lipoprotein family
PIEKEEEF_00613	1e-190	metN			P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIEKEEEF_00614	2e-73	metI			P	ABC transporter permease
PIEKEEEF_00615	9e-267	fumC	4.2.1.2		C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIEKEEEF_00616	1.9e-261	frdC	1.3.5.4		C	FAD binding domain
PIEKEEEF_00617	3.1e-170	ldh	1.1.1.27		C	Belongs to the LDH MDH superfamily. LDH family
PIEKEEEF_00618	9.1e-253	pepC	3.4.22.40		E	Peptidase C1-like family
PIEKEEEF_00619	1.3e-133	hxlA	6.2.1.3		H	Aldolase/RraA
PIEKEEEF_00620	5.2e-273				P	Sodium:sulfate symporter transmembrane region
PIEKEEEF_00621	5.8e-76	ydjP			I	Alpha/beta hydrolase family
PIEKEEEF_00622	1.4e-62	ydjP			I	Alpha/beta hydrolase family
PIEKEEEF_00623	1.1e-195	citC	6.2.1.22		H	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PIEKEEEF_00624	1.2e-43	citD			C	Covalent carrier of the coenzyme of citrate lyase
PIEKEEEF_00625	9e-167	citE	4.1.3.25, 4.1.3.34		G	Belongs to the HpcH HpaI aldolase family
PIEKEEEF_00626	4.9e-290	citF	2.8.3.10		H	Citrate (pro-3S)-lyase alpha chain
PIEKEEEF_00627	9.3e-72	yeaL			S	Protein of unknown function (DUF441)
PIEKEEEF_00628	7e-22
PIEKEEEF_00629	1e-145	cbiQ			P	cobalt transport
PIEKEEEF_00630	0.0	ykoD			P	ABC transporter, ATP-binding protein
PIEKEEEF_00631	6.9e-85				S	UPF0397 protein
PIEKEEEF_00632	2.9e-66				S	Domain of unknown function DUF1828
PIEKEEEF_00633	5.5e-09
PIEKEEEF_00634	2.3e-42
PIEKEEEF_00635	2.6e-177	citR			K	Putative sugar-binding domain
PIEKEEEF_00636	2.9e-249	yjjP			S	Putative threonine/serine exporter
PIEKEEEF_00637	2.8e-14				M	domain protein
PIEKEEEF_00638	6.6e-62
PIEKEEEF_00639	2.5e-11
PIEKEEEF_00640	8.2e-85	ybaK			S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIEKEEEF_00641	1.9e-175	prmA			J	Ribosomal protein L11 methyltransferase
PIEKEEEF_00642	2.9e-60
PIEKEEEF_00643	0.0	relA	2.7.6.5		KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIEKEEEF_00644	6e-76	dtd			J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIEKEEEF_00645	6.8e-245	hisS	6.1.1.21		J	histidyl-tRNA synthetase
PIEKEEEF_00646	0.0	aspS	6.1.1.12		J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIEKEEEF_00647	2e-222	patA	2.6.1.1		E	Aminotransferase
PIEKEEEF_00649	2.8e-216	coaBC	4.1.1.36, 6.3.2.5		H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIEKEEEF_00650	2.2e-34				S	reductase
PIEKEEEF_00651	2.3e-99				S	reductase
PIEKEEEF_00652	5.2e-150	yxeH			S	hydrolase
PIEKEEEF_00653	8e-182	gyaR	1.1.1.26, 2.7.1.165		CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIEKEEEF_00654	9e-243	yfnA			E	Amino Acid
PIEKEEEF_00655	3.4e-109	dedA	3.1.3.1		S	SNARE associated Golgi protein
PIEKEEEF_00656	0.0	uvrC			L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIEKEEEF_00657	1.7e-243	obg			S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIEKEEEF_00658	6.3e-295				I	Acyltransferase
PIEKEEEF_00659	2.2e-176	rnz	3.1.26.11		J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIEKEEEF_00660	3.6e-143	XK27_05435	1.1.1.100		S	Belongs to the short-chain dehydrogenases reductases (SDR) family
PIEKEEEF_00661	3.9e-32	yrvD			S	Lipopolysaccharide assembly protein A domain
PIEKEEEF_00662	1.3e-27	rpmF			J	Belongs to the bacterial ribosomal protein bL32 family
PIEKEEEF_00663	2.6e-310	cpdB	3.1.3.6, 3.1.4.16		F	Belongs to the 5'-nucleotidase family
PIEKEEEF_00664	2.3e-23				S	Protein of unknown function (DUF2929)
PIEKEEEF_00665	0.0	dnaE	2.7.7.7		L	DNA polymerase
PIEKEEEF_00666	3.3e-183	pfkA	2.7.1.11		F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIEKEEEF_00667	0.0	pyk	2.7.1.40, 2.7.7.4		G	Belongs to the pyruvate kinase family
PIEKEEEF_00668	1e-167	cvfB			S	S1 domain
PIEKEEEF_00669	7.6e-166	xerD			D	recombinase XerD
PIEKEEEF_00670	2.6e-61	ribT			K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIEKEEEF_00671	7.6e-132	scpA			D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIEKEEEF_00672	4.1e-104	scpB			D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIEKEEEF_00673	3.1e-130	rluB	5.4.99.19, 5.4.99.21, 5.4.99.22		J	Belongs to the pseudouridine synthase RsuA family
PIEKEEEF_00674	1.9e-113				U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIEKEEEF_00675	2.7e-18				M	Lysin motif
PIEKEEEF_00676	2.2e-114	cmk	1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1		F	Belongs to the cytidylate kinase family. Type 1 subfamily
PIEKEEEF_00677	5.5e-212	rpsA	1.17.7.4		J	Ribosomal protein S1
PIEKEEEF_00678	5.7e-247	der	1.1.1.399, 1.1.1.95		S	GTPase that plays an essential role in the late steps of ribosome biogenesis
PIEKEEEF_00679	2.3e-41	hup			L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIEKEEEF_00680	2.5e-228				S	Tetratricopeptide repeat protein
PIEKEEEF_00681	5.8e-288	cls			I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIEKEEEF_00682	2.3e-282				V	ABC transporter transmembrane region
PIEKEEEF_00683	4.8e-49
PIEKEEEF_00684	6e-17				K	LysR substrate binding domain
PIEKEEEF_00685	1e-20
PIEKEEEF_00686	2.3e-215				S	Sterol carrier protein domain
PIEKEEEF_00687	2.4e-95	citX	2.4.2.52, 2.7.7.61		HI	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PIEKEEEF_00688	9.4e-108	argF	2.1.3.3, 2.7.2.2		E	Belongs to the carbamate kinase family
PIEKEEEF_00689	2.1e-65	argF	2.1.3.3, 2.7.2.2		E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PIEKEEEF_00690	8.8e-234	arcA	3.5.3.6		E	Arginine
PIEKEEEF_00691	9e-137	lysR5			K	LysR substrate binding domain
PIEKEEEF_00692	0.0	mgtA	3.6.3.2, 3.6.3.6		P	Cation transporter/ATPase, N-terminus
PIEKEEEF_00693	2.3e-43	ybhL			S	Belongs to the BI1 family
PIEKEEEF_00694	1.6e-210				S	Bacterial protein of unknown function (DUF871)
PIEKEEEF_00695	6.9e-200	merA	1.16.1.1, 1.8.1.7		C	Pyridine nucleotide-disulfide oxidoreductase
PIEKEEEF_00697	8.7e-86				L	COG2963 Transposase and inactivated derivatives
PIEKEEEF_00698	5.6e-43
PIEKEEEF_00699	1.2e-94	apt	2.4.2.22, 2.4.2.7		F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIEKEEEF_00700	0.0	recJ			L	Single-stranded-DNA-specific exonuclease RecJ
PIEKEEEF_00701	1.5e-102	srtA	3.4.22.70		M	sortase family
PIEKEEEF_00702	0.0	lepA			M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIEKEEEF_00703	5.8e-203	dnaJ			O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIEKEEEF_00704	0.0	dnaK			O	Heat shock 70 kDa protein
PIEKEEEF_00705	8e-68	grpE			O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIEKEEEF_00706	4.5e-194	hrcA			K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIEKEEEF_00707	8.3e-176	ribF	2.7.1.26, 2.7.7.2		H	Belongs to the ribF family
PIEKEEEF_00708	1.6e-155	truB	5.4.99.25		J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIEKEEEF_00709	1.1e-59	rbfA			J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIEKEEEF_00710	0.0	infB			J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIEKEEEF_00711	3.2e-47	rplGA			J	ribosomal protein
PIEKEEEF_00712	8.8e-47	ylxR			K	Protein of unknown function (DUF448)
PIEKEEEF_00713	1.7e-197	nusA			K	Participates in both transcription termination and antitermination
PIEKEEEF_00714	2.5e-83	rimP			J	Required for maturation of 30S ribosomal subunits
PIEKEEEF_00715	0.0	polC	2.7.7.7		L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIEKEEEF_00716	0.0	proS	6.1.1.15		J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIEKEEEF_00717	5.7e-196	rseP	3.4.21.107, 3.4.21.116		M	zinc metalloprotease
PIEKEEEF_00718	9.6e-136	cdsA	2.7.7.41		I	Belongs to the CDS family
PIEKEEEF_00719	4.6e-137	uppS	2.5.1.31		H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIEKEEEF_00720	5.3e-93	frr			J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIEKEEEF_00721	1.4e-130	pyrH	2.7.4.22		F	Catalyzes the reversible phosphorylation of UMP to UDP
PIEKEEEF_00722	1.6e-183	tsf			J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIEKEEEF_00723	7.2e-141	rpsB			J	Belongs to the universal ribosomal protein uS2 family
PIEKEEEF_00724	7.2e-109	yabB	2.1.1.223		L	Methyltransferase small domain
PIEKEEEF_00725	2.6e-74	yabB	2.1.1.223		L	Methyltransferase small domain
PIEKEEEF_00726	3.2e-115	plsC	2.3.1.51		I	Acyltransferase
PIEKEEEF_00727	2.7e-232	cfa	2.1.1.317, 2.1.1.79		M	cyclopropane-fatty-acyl-phospholipid synthase
PIEKEEEF_00728	2.5e-57	atl	3.2.1.96, 3.5.1.28	GH73	UW	LPXTG-motif cell wall anchor domain protein
PIEKEEEF_00729	1.7e-32
PIEKEEEF_00731	0.0	pepO	3.4.24.71		O	Peptidase family M13
PIEKEEEF_00732	5.7e-306	mdlB			V	ABC transporter
PIEKEEEF_00733	0.0	mdlA			V	ABC transporter
PIEKEEEF_00734	1.2e-29	yneF			S	Uncharacterised protein family (UPF0154)
PIEKEEEF_00735	3e-38	ynzC			S	UPF0291 protein
PIEKEEEF_00736	2.2e-111	lexA	3.4.21.88		K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIEKEEEF_00737	5.4e-144				E	GDSL-like Lipase/Acylhydrolase family
PIEKEEEF_00738	4.9e-122	ung2	3.2.2.27		L	Uracil-DNA glycosylase
PIEKEEEF_00739	1.1e-214				S	SLAP domain
PIEKEEEF_00740	1.1e-56	rplS			J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIEKEEEF_00741	5e-136	trmD	2.1.1.228, 4.6.1.12		J	Belongs to the RNA methyltransferase TrmD family
PIEKEEEF_00742	2.2e-93	rimM			J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIEKEEEF_00743	7.6e-45	rpsP			J	Belongs to the bacterial ribosomal protein bS16 family
PIEKEEEF_00744	3.8e-228	ffh	3.6.5.4		U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIEKEEEF_00745	5e-54	ylxM			S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIEKEEEF_00746	3.7e-260	yfnA			E	amino acid
PIEKEEEF_00747	0.0				V	FtsX-like permease family
PIEKEEEF_00748	4.1e-133	cysA			V	ABC transporter, ATP-binding protein
PIEKEEEF_00749	1.3e-48
PIEKEEEF_00750	3.6e-287	pipD			E	Dipeptidase
PIEKEEEF_00751	3.2e-162	ftsY			U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIEKEEEF_00752	0.0	smc			D	Required for chromosome condensation and partitioning
PIEKEEEF_00753	1.9e-124	rnc	3.1.26.3		J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIEKEEEF_00754	6e-308	oppA			E	ABC transporter substrate-binding protein
PIEKEEEF_00755	2.9e-307	oppA			E	ABC transporter substrate-binding protein
PIEKEEEF_00756	6.2e-131	oppC			P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_00757	2.2e-171	oppB			P	ABC transporter permease
PIEKEEEF_00758	1.5e-170	oppF			P	Belongs to the ABC transporter superfamily
PIEKEEEF_00759	1.1e-192	oppD			P	Belongs to the ABC transporter superfamily
PIEKEEEF_00760	6.4e-35	acpP			IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIEKEEEF_00761	3.7e-182	plsX	2.3.1.15		I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIEKEEEF_00762	0.0	recG	3.6.4.12		L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIEKEEEF_00763	2e-305	yloV			S	DAK2 domain fusion protein YloV
PIEKEEEF_00764	4e-57	asp			S	Asp23 family, cell envelope-related function
PIEKEEEF_00765	1.4e-26	rpmB			J	Belongs to the bacterial ribosomal protein bL28 family
PIEKEEEF_00766	1.2e-123				M	hydrolase, family 25
PIEKEEEF_00768	3.5e-07
PIEKEEEF_00769	1.8e-10				S	Phage uncharacterised protein (Phage_XkdX)
PIEKEEEF_00771	1.5e-30
PIEKEEEF_00772	1.1e-07
PIEKEEEF_00773	2e-33				S	Uncharacterised protein conserved in bacteria (DUF2313)
PIEKEEEF_00774	4e-172	xkdT			S	Baseplate J-like protein
PIEKEEEF_00775	3.5e-63				S	lytic transglycosylase activity
PIEKEEEF_00776	5.1e-54				S	Protein of unknown function (DUF2577)
PIEKEEEF_00777	1.5e-181				S	amidase activity
PIEKEEEF_00778	4.5e-110	ygaU		GH23	S	protein containing LysM domain
PIEKEEEF_00779	5.3e-126				S	phage tail tape measure protein
PIEKEEEF_00781	5.5e-42				S	Pfam:Phage_TAC_5
PIEKEEEF_00782	1.9e-64	xkdM			S	Phage tail tube protein
PIEKEEEF_00783	1.7e-244	xkdK			S	Phage tail sheath C-terminal domain
PIEKEEEF_00785	3.5e-28
PIEKEEEF_00786	8.5e-69				S	Bacteriophage HK97-gp10, putative tail-component
PIEKEEEF_00787	1.6e-58
PIEKEEEF_00788	3.4e-56
PIEKEEEF_00789	3.9e-177
PIEKEEEF_00790	1.8e-85				S	Phage minor structural protein GP20
PIEKEEEF_00791	8.3e-40	hxlR			K	HxlR-like helix-turn-helix
PIEKEEEF_00792	2.4e-69				K	LytTr DNA-binding domain
PIEKEEEF_00793	3.8e-67				S	Protein of unknown function (DUF3021)
PIEKEEEF_00794	8.6e-141				V	ABC transporter
PIEKEEEF_00795	2e-106				S	domain protein
PIEKEEEF_00796	1.3e-49	yyaR			K	Acetyltransferase (GNAT) domain
PIEKEEEF_00797	2.2e-73	infC			J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIEKEEEF_00798	8.1e-28	rpmI			J	Belongs to the bacterial ribosomal protein bL35 family
PIEKEEEF_00799	3e-57	rplT			J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIEKEEEF_00800	2.8e-153	add	3.5.4.4		F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIEKEEEF_00801	1.5e-198	tnpB			L	Putative transposase DNA-binding domain
PIEKEEEF_00802	1.4e-84	yqeG			S	HAD phosphatase, family IIIA
PIEKEEEF_00803	4.4e-200	yqeH			S	Ribosome biogenesis GTPase YqeH
PIEKEEEF_00804	1.2e-123	nadD	2.7.7.18, 3.6.1.55		H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIEKEEEF_00805	6.6e-110	nadD	2.7.6.3, 2.7.7.18		H	Hydrolase, HD family
PIEKEEEF_00806	5.3e-59	rsfS			J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIEKEEEF_00807	1.2e-216	ylbM			S	Belongs to the UPF0348 family
PIEKEEEF_00808	1.8e-96	yceD			S	Uncharacterized ACR, COG1399
PIEKEEEF_00809	1.2e-126				K	response regulator
PIEKEEEF_00810	1.3e-277	arlS	2.7.13.3		T	Histidine kinase
PIEKEEEF_00811	8.5e-17
PIEKEEEF_00812	2.4e-50				S	CAAX protease self-immunity
PIEKEEEF_00813	7.2e-225				S	SLAP domain
PIEKEEEF_00814	3.3e-83				S	Aminoacyl-tRNA editing domain
PIEKEEEF_00815	2.2e-163	yidC			U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIEKEEEF_00816	2.9e-44	acyP	3.6.1.7		C	Belongs to the acylphosphatase family
PIEKEEEF_00817	7.7e-135	spoU	2.1.1.185		J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIEKEEEF_00818	4.5e-58	yodB			K	Transcriptional regulator, HxlR family
PIEKEEEF_00820	1.2e-107	papP			P	ABC transporter, permease protein
PIEKEEEF_00821	2.6e-115				P	ABC transporter permease
PIEKEEEF_00822	1.5e-127	glnQ	3.6.3.21		E	ABC transporter, ATP-binding protein
PIEKEEEF_00823	6.2e-157	cjaA			ET	ABC transporter substrate-binding protein
PIEKEEEF_00824	7.1e-200	pheS	6.1.1.20		J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIEKEEEF_00825	0.0	pheT	6.1.1.20		J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIEKEEEF_00826	4.9e-63	greA			K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIEKEEEF_00827	4.3e-169	ldh	1.1.1.27		C	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PIEKEEEF_00828	3.8e-136	metQ1			P	Belongs to the nlpA lipoprotein family
PIEKEEEF_00829	2.9e-21
PIEKEEEF_00830	5.8e-127	mco			Q	Multicopper oxidase
PIEKEEEF_00831	6e-52	mco			Q	Multicopper oxidase
PIEKEEEF_00832	6.4e-72	mco			Q	Multicopper oxidase
PIEKEEEF_00833	1.4e-139				S	Sucrose-6F-phosphate phosphohydrolase
PIEKEEEF_00834	0.0	oppA			E	ABC transporter
PIEKEEEF_00835	1.9e-233				Q	Imidazolonepropionase and related amidohydrolases
PIEKEEEF_00836	2.7e-246		3.5.1.47		S	Peptidase dimerisation domain
PIEKEEEF_00837	1e-137				S	Protein of unknown function (DUF3100)
PIEKEEEF_00838	9.7e-83				S	An automated process has identified a potential problem with this gene model
PIEKEEEF_00839	1.9e-49				L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PIEKEEEF_00840	2.2e-113				S	SLAP domain
PIEKEEEF_00841	2.2e-89
PIEKEEEF_00842	3.9e-09	isdH			M	Iron Transport-associated domain
PIEKEEEF_00843	2.4e-122				M	Iron Transport-associated domain
PIEKEEEF_00844	6.7e-159	isdE			P	Periplasmic binding protein
PIEKEEEF_00845	5.6e-148	isdF			U	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIEKEEEF_00846	3.8e-73	fhuC	3.6.3.34		HP	abc transporter atp-binding protein
PIEKEEEF_00847	8.1e-28	fhuC	3.6.3.34		HP	abc transporter atp-binding protein
PIEKEEEF_00848	6.7e-44	hup			L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIEKEEEF_00849	1.2e-51				S	Bacterial toxin of type II toxin-antitoxin system, YafQ
PIEKEEEF_00850	1.3e-38				S	RelB antitoxin
PIEKEEEF_00851	5.2e-170		2.7.1.59		G	BadF/BadG/BcrA/BcrD ATPase family
PIEKEEEF_00852	0.0				S	membrane
PIEKEEEF_00853	0.0	pbp2b	3.4.16.4		M	Penicillin-binding Protein
PIEKEEEF_00854	1.2e-20	rpmG			J	Belongs to the bacterial ribosomal protein bL33 family
PIEKEEEF_00855	2.7e-97	ygfA	6.3.3.2		H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIEKEEEF_00856	9e-119	gluP	3.4.21.105		S	Rhomboid family
PIEKEEEF_00857	1.7e-35	yqgQ			S	Bacterial protein of unknown function (DUF910)
PIEKEEEF_00858	1.5e-65	yqhL			P	Rhodanese-like protein
PIEKEEEF_00859	3e-168	miaA	2.5.1.75		F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIEKEEEF_00860	2.2e-224	ynbB	4.4.1.1		P	aluminum resistance
PIEKEEEF_00861	2e-263	glnA	6.3.1.2		E	glutamine synthetase
PIEKEEEF_00862	8.2e-168
PIEKEEEF_00863	1.4e-144
PIEKEEEF_00864	6.6e-225	lmrB			EGP	Major facilitator Superfamily
PIEKEEEF_00865	3.8e-252				E	Amino acid permease
PIEKEEEF_00866	2e-14	yaaO	4.1.1.17, 4.1.1.19		E	Orn/Lys/Arg decarboxylase, C-terminal domain
PIEKEEEF_00867	1.9e-307	yaaO	4.1.1.17, 4.1.1.19		E	Orn/Lys/Arg decarboxylase, C-terminal domain
PIEKEEEF_00868	8.7e-60
PIEKEEEF_00869	1.2e-257	uvrX	2.7.7.7		L	Belongs to the DNA polymerase type-Y family
PIEKEEEF_00870	0.0		3.2.1.20	GH31	G	Belongs to the glycosyl hydrolase 31 family
PIEKEEEF_00871	5.2e-176	lacI3			K	helix_turn _helix lactose operon repressor
PIEKEEEF_00872	1.4e-231	malE			G	Bacterial extracellular solute-binding protein
PIEKEEEF_00873	0.0				O	Belongs to the peptidase S8 family
PIEKEEEF_00874	3.4e-175	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15		G	Dak1 domain
PIEKEEEF_00875	4.2e-93	dhaL	2.7.1.121		S	Dak2
PIEKEEEF_00876	2.5e-54	dhaM	2.7.1.121		S	PTS system fructose IIA component
PIEKEEEF_00877	1.3e-120	glpF			U	Belongs to the MIP aquaporin (TC 1.A.8) family
PIEKEEEF_00878	2.2e-12		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_00879	1.3e-50		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_00880	2e-110				K	LysR family
PIEKEEEF_00881	8.3e-273		1.3.5.4		C	FMN_bind
PIEKEEEF_00882	8.3e-109				K	LysR family
PIEKEEEF_00883	2.4e-227				P	Sodium:sulfate symporter transmembrane region
PIEKEEEF_00884	4.7e-276		1.3.5.4		C	FMN_bind
PIEKEEEF_00885	1.7e-199	msmX			P	Belongs to the ABC transporter superfamily
PIEKEEEF_00886	0.0	rafA	3.2.1.22		G	alpha-galactosidase
PIEKEEEF_00887	4.6e-174	cah5	3.1.1.41		Q	Acetyl xylan esterase (AXE1)
PIEKEEEF_00888	1.1e-237				G	Bacterial extracellular solute-binding protein
PIEKEEEF_00889	1.5e-150				P	ABC-type sugar transport systems, permease components
PIEKEEEF_00890	1.1e-153	malG			U	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_00891	1.5e-56
PIEKEEEF_00892	4.5e-274	bgl	3.2.1.21, 3.2.1.86	GT1	G	Belongs to the glycosyl hydrolase 1 family
PIEKEEEF_00893	3.1e-83				S	Putative inner membrane protein (DUF1819)
PIEKEEEF_00894	1.3e-89				S	Domain of unknown function (DUF1788)
PIEKEEEF_00895	6e-225	FbpA	3.1.21.3, 3.2.1.170	GH38	K	RNA-binding protein homologous to eukaryotic snRNP
PIEKEEEF_00896	1.3e-84				L	helicase activity
PIEKEEEF_00898	2.5e-29	cspA			K	Cold shock protein
PIEKEEEF_00899	3.3e-141	tnp2			L	PFAM Transposase, IS204 IS1001 IS1096 IS1165
PIEKEEEF_00900	9.3e-253	rumA	2.1.1.190		J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIEKEEEF_00901	9.5e-197	pbpX			V	Beta-lactamase
PIEKEEEF_00902	9.2e-232	nhaC			C	Na H antiporter NhaC
PIEKEEEF_00903	1.2e-50
PIEKEEEF_00904	3.1e-106	ybhL			S	Belongs to the BI1 family
PIEKEEEF_00905	7.2e-172	yegS	2.7.1.107		G	Lipid kinase
PIEKEEEF_00906	4.1e-275	gatB	6.1.1.12, 6.3.5.6, 6.3.5.7		J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIEKEEEF_00907	5.2e-270	gatA	6.3.5.6, 6.3.5.7		J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIEKEEEF_00908	1.5e-49	gatC	6.3.5.6, 6.3.5.7		J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIEKEEEF_00909	5.8e-203	camS			S	sex pheromone
PIEKEEEF_00910	0.0	ligA	6.5.1.2		L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIEKEEEF_00911	0.0	pcrA	3.6.4.12		L	ATP-dependent DNA helicase
PIEKEEEF_00912	2.5e-86	acmC	3.2.1.17, 3.2.1.96		NU	mannosyl-glycoprotein
PIEKEEEF_00914	2.8e-84	ydcK			S	Belongs to the SprT family
PIEKEEEF_00915	9.1e-135				M	Glycosyltransferase sugar-binding region containing DXD motif
PIEKEEEF_00916	4.1e-259	epsU			S	Polysaccharide biosynthesis protein
PIEKEEEF_00917	7e-225				M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PIEKEEEF_00918	0.0	pacL	3.6.3.8		P	P-type ATPase
PIEKEEEF_00919	3.6e-213	tnpB			L	Putative transposase DNA-binding domain
PIEKEEEF_00920	1.2e-152	nadE	6.3.1.5		F	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIEKEEEF_00921	2.4e-286	pncB	6.3.4.21		F	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIEKEEEF_00922	2.6e-205	csaB			M	Glycosyl transferases group 1
PIEKEEEF_00923	4.3e-135	tagA	2.4.1.187	GT26	F	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PIEKEEEF_00924	5.1e-71	tagD	2.7.7.15, 2.7.7.39		IM	Glycerol-3-phosphate cytidylyltransferase
PIEKEEEF_00925	3.9e-125	gntR1			K	UTRA
PIEKEEEF_00926	1.1e-179
PIEKEEEF_00927	1.3e-298	oppA2			E	ABC transporter, substratebinding protein
PIEKEEEF_00930	2.2e-241	npr	1.11.1.1		C	NADH oxidase
PIEKEEEF_00931	7.7e-12
PIEKEEEF_00932	1.3e-22		3.6.4.12		S	transposase or invertase
PIEKEEEF_00933	2.3e-228	slpX			S	SLAP domain
PIEKEEEF_00934	4.4e-144				K	SIS domain
PIEKEEEF_00935	1.2e-120	rpiA	5.3.1.6		G	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PIEKEEEF_00936	1.1e-186	XK27_10475			S	Oxidoreductase family, NAD-binding Rossmann fold
PIEKEEEF_00937	1.8e-212	patA	2.6.1.1, 2.6.1.57		E	Aminotransferase
PIEKEEEF_00938	0.0	mgtA	3.6.3.2		P	COG0474 Cation transport ATPase
PIEKEEEF_00940	9.6e-113	glpQ1	3.1.4.46		C	glycerophosphoryl diester phosphodiesterase
PIEKEEEF_00941	6.2e-117	VY92_08690	5.3.1.32		G	Antibiotic biosynthesis monooxygenase
PIEKEEEF_00942	2.6e-89				G	Histidine phosphatase superfamily (branch 1)
PIEKEEEF_00943	1.2e-105				G	Phosphoglycerate mutase family
PIEKEEEF_00944	4.7e-159				D	nuclear chromosome segregation
PIEKEEEF_00945	7.5e-78				M	LysM domain protein
PIEKEEEF_00946	4.2e-28	celB			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00947	7.4e-115	celB			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00948	6.2e-12
PIEKEEEF_00949	4e-172	pphA	3.1.3.16		T	Calcineurin-like phosphoesterase
PIEKEEEF_00950	4.6e-31
PIEKEEEF_00952	1.5e-70				S	Iron-sulphur cluster biosynthesis
PIEKEEEF_00953	1.3e-113	yncA	2.3.1.79		S	Maltose acetyltransferase
PIEKEEEF_00954	1e-61	psiE			S	Phosphate-starvation-inducible E
PIEKEEEF_00956	1.7e-200	amtB			P	ammonium transporter
PIEKEEEF_00957	2.6e-141	nfrA	1.5.1.38, 1.5.1.39		C	nitroreductase
PIEKEEEF_00958	5.7e-59
PIEKEEEF_00959	1.1e-291	lhr			L	DEAD DEAH box helicase
PIEKEEEF_00960	9.1e-142	lhr			L	DEAD DEAH box helicase
PIEKEEEF_00961	5.4e-253				P	P-loop Domain of unknown function (DUF2791)
PIEKEEEF_00962	0.0				S	TerB-C domain
PIEKEEEF_00963	0.0	pckA	4.1.1.49		H	Phosphoenolpyruvate carboxykinase
PIEKEEEF_00964	3.9e-298				V	ABC transporter transmembrane region
PIEKEEEF_00966	2.3e-156				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_00967	4.2e-71	apfA	2.7.7.72, 3.6.1.61		F	Nudix hydrolase
PIEKEEEF_00968	2.5e-33
PIEKEEEF_00969	2.8e-20		4.1.1.44		S	Carboxymuconolactone decarboxylase family
PIEKEEEF_00970	1.3e-85		4.1.1.44		S	Carboxymuconolactone decarboxylase family
PIEKEEEF_00971	1.8e-220	mtlD	1.1.1.17		C	mannitol-1-phosphate 5-dehydrogenase activity
PIEKEEEF_00972	2.1e-79	mtlF	2.7.1.197		G	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_00973	0.0	mtlA	2.7.1.197		G	PTS system, Lactose/Cellobiose specific IIB subunit
PIEKEEEF_00974	0.0	mtlR			K	Mga helix-turn-helix domain
PIEKEEEF_00975	0.0	glmS	2.6.1.16		M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIEKEEEF_00976	0.0	adhE	1.1.1.1, 1.2.1.10		C	belongs to the iron- containing alcohol dehydrogenase family
PIEKEEEF_00977	1.6e-244	cycA			E	Amino acid permease
PIEKEEEF_00978	9.9e-86	maa			S	transferase hexapeptide repeat
PIEKEEEF_00979	2.6e-36				K	Transcriptional regulator
PIEKEEEF_00980	5.2e-23				K	Transcriptional regulator
PIEKEEEF_00981	2.2e-63	manO			S	Domain of unknown function (DUF956)
PIEKEEEF_00982	2.9e-173	manN			G	system, mannose fructose sorbose family IID component
PIEKEEEF_00983	1.7e-129	manY			G	PTS system
PIEKEEEF_00984	1.1e-186	manL	2.7.1.191		G	PTS system sorbose subfamily IIB component
PIEKEEEF_00985	3.3e-217	metK	2.5.1.6		H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIEKEEEF_00986	2.8e-247	qacA			EGP	Major facilitator Superfamily
PIEKEEEF_00987	0.0	sacX	2.7.1.208, 2.7.1.211		G	phosphotransferase system
PIEKEEEF_00988	5.2e-151	murQ	4.2.1.126		G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIEKEEEF_00989	1.8e-183	yfeW	3.4.16.4		V	Beta-lactamase
PIEKEEEF_00990	1.2e-186				S	Bacterial protein of unknown function (DUF871)
PIEKEEEF_00991	4.5e-144	ybbH_2			K	rpiR family
PIEKEEEF_00992	1.5e-272	cydA	1.10.3.14		C	ubiquinol oxidase
PIEKEEEF_00993	8.2e-177	cydB	1.10.3.14		C	Cytochrome d ubiquinol oxidase subunit II
PIEKEEEF_00994	0.0	cydD			CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PIEKEEEF_00995	1.4e-269	cydD			CO	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PIEKEEEF_00996	5.7e-129	menG	2.1.1.163, 2.1.1.201		H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PIEKEEEF_00997	6.1e-177	hepT	2.5.1.30, 2.5.1.90		H	Belongs to the FPP GGPP synthase family
PIEKEEEF_00998	6.2e-160	menA	2.5.1.74		H	1,4-dihydroxy-2-naphthoate
PIEKEEEF_00999	4.5e-230	ndh	1.6.99.3		C	NADH dehydrogenase
PIEKEEEF_01000	1.3e-42		1.3.5.4		C	FAD binding domain
PIEKEEEF_01001	1.6e-85		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_01002	9.8e-169				K	LysR substrate binding domain
PIEKEEEF_01003	6.4e-122		3.6.1.27		I	Acid phosphatase homologues
PIEKEEEF_01004	0.0	leuS	6.1.1.4		J	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEKEEEF_01005	1.5e-297	ytgP			S	Polysaccharide biosynthesis protein
PIEKEEEF_01006	3.5e-49	pspC			KT	PspC domain
PIEKEEEF_01008	7.9e-241	dacA	3.4.16.4		M	Belongs to the peptidase S11 family
PIEKEEEF_01009	3.7e-154	nnrD	4.2.1.136, 5.1.99.6		H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIEKEEEF_01010	1.6e-99				M	ErfK YbiS YcfS YnhG
PIEKEEEF_01011	0.0	argS	6.1.1.19		J	Arginyl-tRNA synthetase
PIEKEEEF_01012	2.3e-170	fba	4.1.2.13, 4.1.2.29		G	Fructose-1,6-bisphosphate aldolase, class II
PIEKEEEF_01013	1.5e-89		3.6.1.55		L	NUDIX domain
PIEKEEEF_01014	1.2e-34
PIEKEEEF_01015	1.3e-11
PIEKEEEF_01016	2.1e-93		2.7.13.3		T	GHKL domain
PIEKEEEF_01017	2.4e-136				K	LytTr DNA-binding domain
PIEKEEEF_01018	4.6e-109
PIEKEEEF_01020	1.4e-94
PIEKEEEF_01022	1.9e-62	yniG			EGP	Major facilitator Superfamily
PIEKEEEF_01023	4e-37	yniG			EGP	Major facilitator Superfamily
PIEKEEEF_01024	3.2e-182				S	PFAM Archaeal ATPase
PIEKEEEF_01025	2.7e-180				I	transferase activity, transferring acyl groups other than amino-acyl groups
PIEKEEEF_01026	6.1e-122	citG	2.4.2.52, 2.7.7.61		H	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PIEKEEEF_01027	1.6e-140	glpF			U	Belongs to the MIP aquaporin (TC 1.A.8) family
PIEKEEEF_01028	3.6e-111				G	Phosphoglycerate mutase family
PIEKEEEF_01029	0.0	ppsA	2.7.9.2		H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PIEKEEEF_01030	2.5e-150	rluA	5.4.99.23		J	Responsible for synthesis of pseudouridine from uracil
PIEKEEEF_01031	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	penicillin-binding protein
PIEKEEEF_01032	7.2e-56	yheA			S	Belongs to the UPF0342 family
PIEKEEEF_01033	7.4e-233	yhaO			L	Ser Thr phosphatase family protein
PIEKEEEF_01034	0.0				L	AAA domain
PIEKEEEF_01035	6.4e-187	cbf			S	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEKEEEF_01036	2.8e-266
PIEKEEEF_01037	9.5e-72	eda	4.1.2.14, 4.1.3.42		G	KDPG and KHG aldolase
PIEKEEEF_01038	1.1e-151	prsA	5.2.1.8		M	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIEKEEEF_01039	3.9e-25
PIEKEEEF_01040	8.3e-78	hit			FG	Scavenger mRNA decapping enzyme C-term binding
PIEKEEEF_01041	1.7e-134	ecsA			V	ABC transporter, ATP-binding protein
PIEKEEEF_01042	4.2e-220	ecsB			U	ABC transporter
PIEKEEEF_01043	3.3e-126	trmB	2.1.1.297, 2.1.1.33		J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIEKEEEF_01045	2.8e-54	ytpP	2.7.1.180, 5.3.4.1		CO	Thioredoxin
PIEKEEEF_01046	4.3e-123	pheT	6.1.1.20		J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIEKEEEF_01047	5.2e-248	mpl	6.3.2.4, 6.3.2.45, 6.3.2.8		M	Belongs to the MurCDEF family
PIEKEEEF_01048	9.3e-237	mepA			V	MATE efflux family protein
PIEKEEEF_01049	4.5e-172				S	SLAP domain
PIEKEEEF_01050	6.2e-274				M	Peptidase family M1 domain
PIEKEEEF_01051	2.1e-185				S	Bacteriocin helveticin-J
PIEKEEEF_01052	9.1e-47				L	RelB antitoxin
PIEKEEEF_01053	1.4e-132	qmcA			O	prohibitin homologues
PIEKEEEF_01054	1.9e-279				L	Transposase
PIEKEEEF_01055	6.1e-154	yqfL	2.7.11.33, 2.7.4.28		F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIEKEEEF_01056	2e-22	rpsU			J	Belongs to the bacterial ribosomal protein bS21 family
PIEKEEEF_01057	1.3e-70	yqeY			S	YqeY-like protein
PIEKEEEF_01058	3.3e-175	phoH			T	phosphate starvation-inducible protein PhoH
PIEKEEEF_01059	2.2e-93	ybeY	2.6.99.2, 3.5.4.5		S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIEKEEEF_01060	1.4e-167	era			S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIEKEEEF_01061	4.3e-130	recO			L	Involved in DNA repair and RecF pathway recombination
PIEKEEEF_01062	4.6e-179	glyQ	6.1.1.14		J	glycyl-tRNA synthetase alpha subunit
PIEKEEEF_01063	0.0	glyS	6.1.1.14		J	Glycyl-tRNA synthetase beta subunit
PIEKEEEF_01064	0.0	dnaG			L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIEKEEEF_01065	9.9e-200	sigA			K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIEKEEEF_01066	8e-128				S	Peptidase family M23
PIEKEEEF_01067	4.8e-81	mutT	3.6.1.55		F	NUDIX domain
PIEKEEEF_01068	1.2e-123	trmK	2.1.1.217		S	SAM-dependent methyltransferase
PIEKEEEF_01069	3.2e-152	yqfO	3.5.4.16		S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIEKEEEF_01070	1.7e-240	pepT	3.4.11.4		E	Cleaves the N-terminal amino acid of tripeptides
PIEKEEEF_01071	1.4e-60	yvoA_1			K	Transcriptional regulator, GntR family
PIEKEEEF_01072	9.6e-124	skfE			V	ATPases associated with a variety of cellular activities
PIEKEEEF_01073	6e-125
PIEKEEEF_01074	1.9e-104
PIEKEEEF_01075	5.4e-110
PIEKEEEF_01076	4.3e-39	ybjQ			S	Belongs to the UPF0145 family
PIEKEEEF_01077	3.8e-27
PIEKEEEF_01078	3.9e-104	lepB	3.4.21.89		U	Belongs to the peptidase S26 family
PIEKEEEF_01079	2e-143
PIEKEEEF_01080	2.8e-168
PIEKEEEF_01081	6.3e-265	rsmF	2.1.1.176		J	NOL1 NOP2 sun family protein
PIEKEEEF_01082	1.3e-116		3.1.3.102, 3.1.3.104, 3.1.3.23		G	Sucrose-6F-phosphate phosphohydrolase
PIEKEEEF_01083	8.2e-185	fni	1.1.1.88, 5.3.3.2		C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIEKEEEF_01084	2.1e-202	mvaK2	2.7.1.36, 2.7.1.43, 2.7.4.2		I	phosphomevalonate kinase
PIEKEEEF_01085	3.7e-179	mvaD	4.1.1.33		I	diphosphomevalonate decarboxylase
PIEKEEEF_01086	1.3e-136	mvk	1.1.1.88, 2.3.3.10, 2.7.1.36		I	GHMP kinases N terminal domain
PIEKEEEF_01087	0.0	rexB	3.1.21.3, 3.6.4.12		L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PIEKEEEF_01088	0.0	addA	3.6.4.12		L	ATP-dependent helicase nuclease subunit A
PIEKEEEF_01089	0.0	dinG	2.7.7.7, 3.6.4.12		L	helicase involved in DNA repair and perhaps also replication
PIEKEEEF_01090	3.2e-89	ypmB			S	Protein conserved in bacteria
PIEKEEEF_01091	2.9e-259	asnS	6.1.1.22		J	Asparaginyl-tRNA synthetase
PIEKEEEF_01092	1.3e-114	dnaD			L	DnaD domain protein
PIEKEEEF_01093	2.7e-114	nth	4.2.99.18		L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIEKEEEF_01094	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	penicillin-binding protein 1A
PIEKEEEF_01095	4.5e-117	recU			L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIEKEEEF_01096	1e-107	ypsA			S	Belongs to the UPF0398 family
PIEKEEEF_01097	1.1e-68	gpsB			D	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIEKEEEF_01098	3.1e-217	rlmL	2.1.1.173, 2.1.1.264		L	Belongs to the methyltransferase superfamily
PIEKEEEF_01099	1e-242	cpdA			S	Calcineurin-like phosphoesterase
PIEKEEEF_01100	3.4e-79
PIEKEEEF_01101	1.9e-115	rdgB	3.6.1.66, 5.1.1.3		F	Ham1 family
PIEKEEEF_01102	1.4e-34
PIEKEEEF_01103	3.6e-63
PIEKEEEF_01106	4.9e-118
PIEKEEEF_01107	3.8e-104	pncA			Q	Isochorismatase family
PIEKEEEF_01109	2.8e-35
PIEKEEEF_01110	0.0	snf	2.7.11.1		KL	domain protein
PIEKEEEF_01111	3.5e-109	plsY	2.3.1.15, 3.5.1.104		I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIEKEEEF_01112	0.0	parE	5.99.1.3		L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIEKEEEF_01113	0.0	parC	5.99.1.3		L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIEKEEEF_01114	1.9e-183				K	Transcriptional regulator
PIEKEEEF_01115	2.1e-171	ppaC	3.6.1.1		C	inorganic pyrophosphatase
PIEKEEEF_01116	9.3e-112	ppiB	5.2.1.8		G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIEKEEEF_01117	4e-57				K	Helix-turn-helix domain
PIEKEEEF_01118	2.3e-25				L	Belongs to the 'phage' integrase family
PIEKEEEF_01119	4.8e-31
PIEKEEEF_01120	8.2e-125	thiN	2.7.6.2		H	thiamine pyrophosphokinase
PIEKEEEF_01121	1.7e-119	rpe	5.1.3.1		G	Belongs to the ribulose-phosphate 3-epimerase family
PIEKEEEF_01122	4.1e-164	rsgA	3.1.3.100		S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIEKEEEF_01123	0.0	prkC	2.7.11.1		KLT	serine threonine protein kinase
PIEKEEEF_01124	1.1e-138	stp	3.1.3.16		T	phosphatase
PIEKEEEF_01125	3.5e-244	sun	2.1.1.176		J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIEKEEEF_01126	7.4e-172	fmt	2.1.2.9		J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIEKEEEF_01127	0.0	priA			L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIEKEEEF_01128	1.1e-33	rpoZ	2.7.7.6		K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIEKEEEF_01129	2.1e-111	gmk	2.7.4.8, 4.1.1.23		F	Essential for recycling GMP and indirectly, cGMP
PIEKEEEF_01130	1.9e-77		6.3.3.2		S	ASCH
PIEKEEEF_01131	4.8e-307	recN			L	May be involved in recombinational repair of damaged DNA
PIEKEEEF_01132	2.3e-153	rrmJ	2.1.1.226, 2.1.1.227		J	Ribosomal RNA large subunit methyltransferase J
PIEKEEEF_01133	2.4e-161	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90		H	Belongs to the FPP GGPP synthase family
PIEKEEEF_01134	3.7e-35	xseB	3.1.11.6		L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIEKEEEF_01135	7.6e-194	xseA	3.1.11.6		L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIEKEEEF_01136	6.7e-156	folD	1.5.1.5, 3.5.4.9		F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIEKEEEF_01137	2.8e-64	nusB			K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIEKEEEF_01138	9.8e-71	yqhY			S	Asp23 family, cell envelope-related function
PIEKEEEF_01139	4.9e-102	efp			J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIEKEEEF_01140	1e-196	pepP	3.4.11.9, 3.4.13.9		E	Creatinase/Prolidase N-terminal domain
PIEKEEEF_01141	7.8e-48	rpmA			J	Belongs to the bacterial ribosomal protein bL27 family
PIEKEEEF_01142	5.8e-49	rplU			J	This protein binds to 23S rRNA in the presence of protein L20
PIEKEEEF_01143	3.2e-150				S	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEKEEEF_01144	8.6e-254				S	Uncharacterized protein conserved in bacteria (DUF2325)
PIEKEEEF_01146	1.6e-27	dmpI	5.3.2.6		G	Belongs to the 4-oxalocrotonate tautomerase family
PIEKEEEF_01147	9.4e-301				S	Predicted membrane protein (DUF2207)
PIEKEEEF_01148	7.8e-160	cinI			S	Serine hydrolase (FSH1)
PIEKEEEF_01149	7.1e-207				M	Glycosyl hydrolases family 25
PIEKEEEF_01150	4.5e-107				M	hydrolase, family 25
PIEKEEEF_01154	2.8e-110				E	GDSL-like Lipase/Acylhydrolase
PIEKEEEF_01157	4.7e-168				S	Phage minor structural protein
PIEKEEEF_01158	8.9e-35				S	phage tail
PIEKEEEF_01159	6e-151				M	Phage tail tape measure protein TP901
PIEKEEEF_01162	9.1e-27				S	Phage tail tube protein
PIEKEEEF_01163	4.7e-13				S	Protein of unknown function (DUF806)
PIEKEEEF_01164	4.1e-23				S	Bacteriophage HK97-gp10, putative tail-component
PIEKEEEF_01166	1.6e-16				S	Phage gp6-like head-tail connector protein
PIEKEEEF_01167	2.3e-49				S	peptidase activity
PIEKEEEF_01168	6.7e-74	clpP	3.4.21.92		OU	Belongs to the peptidase S14 family
PIEKEEEF_01169	1.6e-128				S	Phage portal protein
PIEKEEEF_01171	7.9e-218				S	Phage Terminase
PIEKEEEF_01174	1.6e-55				L	Phage terminase, small subunit
PIEKEEEF_01175	1.3e-61				L	HNH nucleases
PIEKEEEF_01177	1.5e-08
PIEKEEEF_01182	3.7e-20
PIEKEEEF_01184	2.5e-82	ps308			K	AntA/AntB antirepressor
PIEKEEEF_01190	3.4e-11
PIEKEEEF_01194	3.4e-23		2.1.1.72		V	site-specific DNA-methyltransferase (adenine-specific) activity
PIEKEEEF_01195	2.2e-34				L	Belongs to the 'phage' integrase family
PIEKEEEF_01197	3.7e-21				L	Psort location Cytoplasmic, score
PIEKEEEF_01199	1.4e-20
PIEKEEEF_01202	3.9e-47		3.4.21.88		K	Peptidase S24-like
PIEKEEEF_01204	8.1e-32
PIEKEEEF_01205	3.2e-89				L	Belongs to the 'phage' integrase family
PIEKEEEF_01207	2.9e-178				I	Carboxylesterase family
PIEKEEEF_01208	1.2e-63	arsC	1.20.4.1		P	Belongs to the ArsC family
PIEKEEEF_01209	3.2e-42
PIEKEEEF_01210	6e-41	ps115			K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01211	1.4e-91				E	Zn peptidase
PIEKEEEF_01212	1.2e-35	rpsR			J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIEKEEEF_01213	2.7e-75	ssb			L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIEKEEEF_01214	5.5e-49	rpsF			J	Binds together with S18 to 16S ribosomal RNA
PIEKEEEF_01215	0.0	gyrA	5.99.1.3		L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIEKEEEF_01216	0.0	gyrB	5.99.1.3		L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIEKEEEF_01217	1.1e-209	recF			L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIEKEEEF_01218	2.6e-35	yaaA			S	S4 domain protein YaaA
PIEKEEEF_01219	3.1e-185	dnaN	2.7.7.7		L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIEKEEEF_01220	5.5e-245	dnaA			L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIEKEEEF_01221	1.1e-15	rpmH			J	Belongs to the bacterial ribosomal protein bL34 family
PIEKEEEF_01222	3.5e-61	rnpA	3.1.26.5		J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIEKEEEF_01223	8.4e-146	yidC			U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIEKEEEF_01224	2.1e-252	mnmE			S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIEKEEEF_01225	0.0	gidA			D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIEKEEEF_01226	0.0	poxB	1.2.3.3, 1.2.5.1		EH	Belongs to the TPP enzyme family
PIEKEEEF_01227	1.6e-31
PIEKEEEF_01228	7.6e-274	gnd	1.1.1.343, 1.1.1.44		H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIEKEEEF_01229	5.1e-287	clcA			P	chloride
PIEKEEEF_01230	4e-32				E	Zn peptidase
PIEKEEEF_01231	3.7e-58	ps115			K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01232	4.5e-136				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_01233	3.3e-242	yisQ			V	MatE
PIEKEEEF_01234	3.5e-199				V	MatE
PIEKEEEF_01235	5.3e-130				GK	ROK family
PIEKEEEF_01236	1.7e-42	rhaS6			K	helix_turn_helix, arabinose operon control protein
PIEKEEEF_01237	1.1e-82				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_01238	8e-210
PIEKEEEF_01239	1.2e-18
PIEKEEEF_01240	7e-248				EGP	Sugar (and other) transporter
PIEKEEEF_01241	1.2e-105
PIEKEEEF_01242	3.2e-17	flpA	4.1.99.16, 4.2.3.22, 4.2.3.75		K	helix_turn_helix, cAMP Regulatory protein
PIEKEEEF_01243	3.4e-80	flpA	4.1.99.16, 4.2.3.22, 4.2.3.75		K	helix_turn_helix, cAMP Regulatory protein
PIEKEEEF_01244	0.0	copA	3.6.3.54		P	P-type ATPase
PIEKEEEF_01245	1.8e-44	silP	1.9.3.1, 3.6.3.54		S	Cupredoxin-like domain
PIEKEEEF_01246	9.2e-57	silP	1.9.3.1, 3.6.3.54		S	Cupredoxin-like domain
PIEKEEEF_01247	1.1e-36
PIEKEEEF_01250	1.8e-31
PIEKEEEF_01251	1.1e-139
PIEKEEEF_01252	8.3e-261				V	ABC transporter transmembrane region
PIEKEEEF_01253	9.1e-37				S	Putative adhesin
PIEKEEEF_01254	2.5e-226	pbuG			S	permease
PIEKEEEF_01255	7.2e-132				S	haloacid dehalogenase-like hydrolase
PIEKEEEF_01256	3e-139				S	cog cog1373
PIEKEEEF_01257	3.4e-75				S	cog cog1373
PIEKEEEF_01258	1.1e-34				K	Transcriptional regulator
PIEKEEEF_01259	1.5e-93				K	Transcriptional regulator
PIEKEEEF_01260	5.2e-41		1.1.1.100		S	Enoyl-(Acyl carrier protein) reductase
PIEKEEEF_01261	6.3e-49		1.1.1.100		S	Enoyl-(Acyl carrier protein) reductase
PIEKEEEF_01262	6.9e-16				S	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIEKEEEF_01263	2.5e-40	relB			L	Addiction module antitoxin, RelB DinJ family
PIEKEEEF_01264	3e-232	pbuG			S	permease
PIEKEEEF_01265	3.8e-128				K	helix_turn_helix, mercury resistance
PIEKEEEF_01266	5e-32				S	CAAX protease self-immunity
PIEKEEEF_01268	2.2e-230	pbuG			S	permease
PIEKEEEF_01269	7.2e-144	cof			S	haloacid dehalogenase-like hydrolase
PIEKEEEF_01270	9.4e-72
PIEKEEEF_01271	9.3e-124	dgk	2.7.1.74, 2.7.1.76		F	deoxynucleoside kinase
PIEKEEEF_01272	8.5e-119	dak	2.7.1.74, 2.7.1.76		F	deoxynucleoside kinase
PIEKEEEF_01273	2.1e-134	nagB	3.1.1.31, 3.5.99.6		G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIEKEEEF_01274	4.3e-160	yeaE			S	Aldo/keto reductase family
PIEKEEEF_01275	4.4e-172	yufQ			S	Belongs to the binding-protein-dependent transport system permease family
PIEKEEEF_01276	2.4e-196	yufP			S	Belongs to the binding-protein-dependent transport system permease family
PIEKEEEF_01277	2e-283	xylG	3.6.3.17		S	ABC transporter
PIEKEEEF_01278	1.5e-200	tcsA			S	ABC transporter substrate-binding protein PnrA-like
PIEKEEEF_01279	4.7e-202	tcsA			S	ABC transporter substrate-binding protein PnrA-like
PIEKEEEF_01280	1.1e-164				UW	LPXTG-motif cell wall anchor domain protein
PIEKEEEF_01281	6.8e-23				UW	LPXTG-motif cell wall anchor domain protein
PIEKEEEF_01282	1.8e-237	serS	6.1.1.11		J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIEKEEEF_01283	5.4e-98				J	Acetyltransferase (GNAT) domain
PIEKEEEF_01284	1.4e-110	yjbF			S	SNARE associated Golgi protein
PIEKEEEF_01285	9.3e-152				I	alpha/beta hydrolase fold
PIEKEEEF_01286	4.7e-149	hipB			K	Helix-turn-helix
PIEKEEEF_01287	9.9e-83				F	Nucleoside 2-deoxyribosyltransferase
PIEKEEEF_01288	6.6e-254	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79		C	Belongs to the aldehyde dehydrogenase family
PIEKEEEF_01289	1e-150
PIEKEEEF_01290	0.0	ydgH			S	MMPL family
PIEKEEEF_01291	2.3e-99	yobS			K	Bacterial regulatory proteins, tetR family
PIEKEEEF_01292	3.7e-147		3.5.2.6		V	Beta-lactamase enzyme family
PIEKEEEF_01293	1.8e-154	corA			P	CorA-like Mg2+ transporter protein
PIEKEEEF_01294	9.6e-239				G	Bacterial extracellular solute-binding protein
PIEKEEEF_01295	3.5e-257	YSH1			S	Zn-dependent metallo-hydrolase RNA specificity domain
PIEKEEEF_01296	6.1e-146	gtsC			P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_01297	7.3e-158	gtsB			P	ABC-type sugar transport systems, permease components
PIEKEEEF_01298	1.2e-202	malK			P	ATPases associated with a variety of cellular activities
PIEKEEEF_01299	1.2e-282	pipD			E	Dipeptidase
PIEKEEEF_01300	7.2e-158	endA			F	DNA RNA non-specific endonuclease
PIEKEEEF_01301	3.2e-183	dnaQ	2.7.7.7		L	EXOIII
PIEKEEEF_01302	2.4e-158				K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PIEKEEEF_01303	3e-116	yviA			S	Protein of unknown function (DUF421)
PIEKEEEF_01304	1.1e-72				S	Protein of unknown function (DUF3290)
PIEKEEEF_01305	9e-141	pnuC			H	nicotinamide mononucleotide transporter
PIEKEEEF_01306	1.4e-13
PIEKEEEF_01307	4.6e-129				S	PAS domain
PIEKEEEF_01308	6.5e-277				V	ABC transporter transmembrane region
PIEKEEEF_01309	8.7e-178	pip	3.4.11.5		E	Releases the N-terminal proline from various substrates
PIEKEEEF_01310	5.7e-132				T	Transcriptional regulatory protein, C terminal
PIEKEEEF_01311	5.3e-248				T	GHKL domain
PIEKEEEF_01312	2.1e-86				S	Peptidase propeptide and YPEB domain
PIEKEEEF_01313	8.9e-102				S	Peptidase propeptide and YPEB domain
PIEKEEEF_01314	4.5e-94	paiA	2.3.1.57		K	Acetyltransferase (GNAT) domain
PIEKEEEF_01315	8.2e-76	yybA	2.3.1.57		K	Transcriptional regulator
PIEKEEEF_01316	0.0	oppA3			E	ABC transporter, substratebinding protein
PIEKEEEF_01317	9.9e-62	ypaA			S	Protein of unknown function (DUF1304)
PIEKEEEF_01318	1.5e-101				S	Peptidase propeptide and YPEB domain
PIEKEEEF_01319	4.4e-103	efp			J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIEKEEEF_01320	2.1e-171	coaA	2.7.1.33		F	Pantothenic acid kinase
PIEKEEEF_01321	4.9e-99				E	GDSL-like Lipase/Acylhydrolase
PIEKEEEF_01322	6.4e-73	yjcF			S	Acetyltransferase (GNAT) domain
PIEKEEEF_01323	1.3e-145	aatB			ET	ABC transporter substrate-binding protein
PIEKEEEF_01324	2.9e-108	glnQ	3.6.3.21		E	ABC transporter
PIEKEEEF_01325	2.1e-109	glnP			P	ABC transporter permease
PIEKEEEF_01326	0.0	helD	3.6.4.12		L	DNA helicase
PIEKEEEF_01327	5.6e-118	XK27_08875			O	PFAM peptidase M10A and M12B, matrixin and adamalysin
PIEKEEEF_01328	1.4e-126	pgm3			G	Phosphoglycerate mutase family
PIEKEEEF_01329	1.2e-241				S	response to antibiotic
PIEKEEEF_01330	2.9e-125
PIEKEEEF_01331	0.0		3.6.3.8		P	P-type ATPase
PIEKEEEF_01332	1.5e-65		2.7.1.191		G	PTS system fructose IIA component
PIEKEEEF_01333	2.1e-42
PIEKEEEF_01334	7.7e-09
PIEKEEEF_01335	2.7e-185	ansA	3.5.1.1		EJ	L-asparaginase, type I
PIEKEEEF_01336	1.8e-136	glvR			K	Helix-turn-helix domain, rpiR family
PIEKEEEF_01337	2.7e-268	aglB	3.2.1.122, 3.2.1.86	GH4,GT4	G	Family 4 glycosyl hydrolase C-terminal domain
PIEKEEEF_01338	9.5e-48
PIEKEEEF_01339	8.6e-24
PIEKEEEF_01340	2e-89	hpt	2.4.2.8		F	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIEKEEEF_01341	9.4e-106		3.2.2.20		K	acetyltransferase
PIEKEEEF_01343	6.9e-44				S	polysaccharide biosynthetic process
PIEKEEEF_01344	1.4e-39				S	Bacterial protein of unknown function (DUF871)
PIEKEEEF_01346	1.8e-27
PIEKEEEF_01348	1.1e-31				S	Bacteriocin class II with double-glycine leader peptide
PIEKEEEF_01349	5.4e-30
PIEKEEEF_01350	8.6e-145				K	LytTr DNA-binding domain
PIEKEEEF_01351	1.9e-237		2.7.13.3		T	GHKL domain
PIEKEEEF_01353	2.3e-210				S	CAAX protease self-immunity
PIEKEEEF_01355	9.2e-220				S	CAAX protease self-immunity
PIEKEEEF_01357	1.9e-68
PIEKEEEF_01358	6.4e-11
PIEKEEEF_01359	0.0	malZ	3.2.1.20	GH31	G	Belongs to the glycosyl hydrolase 31 family
PIEKEEEF_01360	6e-271	glcD2	1.1.3.15		C	FAD linked oxidases, C-terminal domain
PIEKEEEF_01361	1e-24
PIEKEEEF_01362	9.5e-26
PIEKEEEF_01363	2.5e-33
PIEKEEEF_01364	6.2e-54				S	Enterocin A Immunity
PIEKEEEF_01365	8e-145	racD	5.1.1.13		M	Belongs to the aspartate glutamate racemases family
PIEKEEEF_01366	5.5e-305	murE	6.3.2.13, 6.3.2.7		M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIEKEEEF_01367	4.6e-208	hpk31	2.7.13.3		T	His Kinase A (phospho-acceptor) domain
PIEKEEEF_01368	9.6e-121				K	response regulator
PIEKEEEF_01369	3e-39				S	HicB family
PIEKEEEF_01370	1.8e-205				L	Probable transposase
PIEKEEEF_01372	0.0				V	ABC transporter
PIEKEEEF_01373	7.4e-303				V	ABC transporter, ATP-binding protein
PIEKEEEF_01374	9.3e-136	XK27_01040			S	Protein of unknown function (DUF1129)
PIEKEEEF_01375	3.6e-202	ychF			J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIEKEEEF_01376	9.6e-45	yyzM			S	Bacterial protein of unknown function (DUF951)
PIEKEEEF_01377	3.2e-153	spo0J			K	Belongs to the ParB family
PIEKEEEF_01378	3.4e-138	soj			D	Sporulation initiation inhibitor
PIEKEEEF_01379	1.3e-148	noc			K	Belongs to the ParB family
PIEKEEEF_01380	1.2e-129	rsmG	2.1.1.170		J	Specifically methylates the N7 position of a guanine in 16S rRNA
PIEKEEEF_01381	3e-53	cvpA			S	Colicin V production protein
PIEKEEEF_01382	2.5e-180	apbE	2.7.1.180		H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIEKEEEF_01383	6e-151		3.1.3.48		T	Tyrosine phosphatase family
PIEKEEEF_01384	2e-97	azr	1.5.1.36		S	NADPH-dependent FMN reductase
PIEKEEEF_01385	6.4e-96	nqr	1.5.1.36		S	NADPH-dependent FMN reductase
PIEKEEEF_01386	3.7e-111				K	WHG domain
PIEKEEEF_01387	8e-38
PIEKEEEF_01388	2.8e-276	pipD			E	Dipeptidase
PIEKEEEF_01389	1.5e-102	devA	3.6.3.25		V	ABC transporter, ATP-binding protein
PIEKEEEF_01390	1.4e-174	hrtB			V	ABC transporter permease
PIEKEEEF_01391	3.1e-95	ygfC			K	Bacterial regulatory proteins, tetR family
PIEKEEEF_01392	5.5e-112				G	phosphoglycerate mutase
PIEKEEEF_01393	4.9e-142	aroD			S	Alpha/beta hydrolase family
PIEKEEEF_01394	2.9e-142				S	Belongs to the UPF0246 family
PIEKEEEF_01395	1.2e-120
PIEKEEEF_01396	1.6e-159		2.7.7.12		C	Domain of unknown function (DUF4931)
PIEKEEEF_01397	3.4e-198				S	Putative peptidoglycan binding domain
PIEKEEEF_01398	3.4e-15
PIEKEEEF_01399	6.6e-243				L	transposase, IS605 OrfB family
PIEKEEEF_01400	5.4e-128	liaI			S	membrane
PIEKEEEF_01401	3e-78	XK27_02470			K	LytTr DNA-binding domain
PIEKEEEF_01404	1.9e-45				K	LytTr DNA-binding domain
PIEKEEEF_01405	1.7e-46		2.7.13.3		T	GHKL domain
PIEKEEEF_01406	1.8e-249	dtpT			U	amino acid peptide transporter
PIEKEEEF_01407	0.0	pepN	3.4.11.2		E	aminopeptidase
PIEKEEEF_01408	2.8e-47	lysM			M	LysM domain
PIEKEEEF_01409	2.6e-175
PIEKEEEF_01410	2.4e-210	mdtG			EGP	Major facilitator Superfamily
PIEKEEEF_01411	1.4e-89	ymdB			S	Macro domain protein
PIEKEEEF_01413	3.2e-20
PIEKEEEF_01414	2e-122				S	CAAX amino terminal protease
PIEKEEEF_01415	1.1e-08				S	CAAX amino terminal protease
PIEKEEEF_01416	8.8e-89	luxS	4.4.1.21		H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIEKEEEF_01417	4.4e-216		2.1.1.14		E	methionine synthase, vitamin-B12 independent
PIEKEEEF_01418	2.6e-11
PIEKEEEF_01419	2e-25				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01422	1.9e-78		2.7.13.3		T	GHKL domain
PIEKEEEF_01423	1.3e-79				K	LytTr DNA-binding domain
PIEKEEEF_01424	0.0	comA			V	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIEKEEEF_01425	5.7e-43		2.4.1.33		V	HlyD family secretion protein
PIEKEEEF_01427	1e-20				S	Enterocin A Immunity
PIEKEEEF_01431	1.2e-29	blpT
PIEKEEEF_01432	4.6e-27				S	Enterocin A Immunity
PIEKEEEF_01434	1.3e-69	doc			S	Prophage maintenance system killer protein
PIEKEEEF_01435	2.9e-31
PIEKEEEF_01436	0.0	pepF			E	oligoendopeptidase F
PIEKEEEF_01437	7.6e-209	brpA			K	Cell envelope-like function transcriptional attenuator common domain protein
PIEKEEEF_01438	6.5e-125				S	Protein of unknown function (DUF554)
PIEKEEEF_01439	4.6e-97	rimL			J	Acetyltransferase (GNAT) domain
PIEKEEEF_01440	2.5e-62
PIEKEEEF_01441	1.1e-289				S	ABC transporter
PIEKEEEF_01442	8.5e-126	thrE			S	Putative threonine/serine exporter
PIEKEEEF_01443	2e-72				S	Threonine/Serine exporter, ThrE
PIEKEEEF_01444	9.1e-112	yvpB			S	Peptidase_C39 like family
PIEKEEEF_01445	2.5e-68
PIEKEEEF_01446	6.8e-178	nrdF	1.17.4.1		F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIEKEEEF_01447	1.9e-77	nrdI			F	NrdI Flavodoxin like
PIEKEEEF_01448	3.3e-112
PIEKEEEF_01449	2.9e-279				S	O-antigen ligase like membrane protein
PIEKEEEF_01450	3.9e-42
PIEKEEEF_01451	7.7e-89	gmk2	2.7.4.8		F	Guanylate kinase homologues.
PIEKEEEF_01452	4.3e-87				M	NlpC/P60 family
PIEKEEEF_01453	1.4e-136				M	NlpC P60 family protein
PIEKEEEF_01454	2.2e-117				M	NlpC/P60 family
PIEKEEEF_01455	4.6e-41
PIEKEEEF_01457	7.2e-175				S	Cysteine-rich secretory protein family
PIEKEEEF_01458	2.7e-217	hflX			S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIEKEEEF_01460	1.3e-41	relB			L	RelB antitoxin
PIEKEEEF_01461	2.4e-46	yoeB			S	YoeB-like toxin of bacterial type II toxin-antitoxin system
PIEKEEEF_01462	5.5e-176	brpA			K	Cell envelope-like function transcriptional attenuator common domain protein
PIEKEEEF_01463	6.5e-146	epsB			M	biosynthesis protein
PIEKEEEF_01464	9.9e-122	ywqD	2.7.10.1		D	Capsular exopolysaccharide family
PIEKEEEF_01465	6.5e-142	ywqE	3.1.3.48		GM	PHP domain protein
PIEKEEEF_01466	3.1e-121	rfbP			M	Bacterial sugar transferase
PIEKEEEF_01467	9.2e-129				M	Glycosyltransferase
PIEKEEEF_01468	3.5e-79	cpsF			M	Oligosaccharide biosynthesis protein Alg14 like
PIEKEEEF_01469	1.2e-86				M	Glycosyltransferase
PIEKEEEF_01470	7.5e-59	pssE			S	Glycosyltransferase family 28 C-terminal domain
PIEKEEEF_01472	1.1e-119	epsI			GM	polysaccharide biosynthetic process
PIEKEEEF_01473	5e-138				S	Psort location CytoplasmicMembrane, score 9.99
PIEKEEEF_01474	1.1e-56				S	Acyltransferase family
PIEKEEEF_01475	7.2e-145	galU	2.7.7.9		M	UTP-glucose-1-phosphate uridylyltransferase
PIEKEEEF_01478	1.5e-244				K	Psort location Cytoplasmic, score
PIEKEEEF_01482	4.7e-24
PIEKEEEF_01483	1.6e-46				S	Domain of unknown function (DUF4417)
PIEKEEEF_01484	3e-30				E	IrrE N-terminal-like domain
PIEKEEEF_01485	1.4e-29				K	Helix-turn-helix
PIEKEEEF_01486	1.9e-68				L	Transposase
PIEKEEEF_01487	3.4e-49				L	transposase, IS605 OrfB family
PIEKEEEF_01488	1.6e-129				L	transposase, IS605 OrfB family
PIEKEEEF_01489	0.0				S	PglZ domain
PIEKEEEF_01491	1.2e-186				K	Periplasmic binding protein-like domain
PIEKEEEF_01492	2e-106				K	Transcriptional regulator, AbiEi antitoxin
PIEKEEEF_01493	1.7e-162				S	Nucleotidyl transferase AbiEii toxin, Type IV TA system
PIEKEEEF_01494	2e-188	galE	5.1.3.2		M	Belongs to the NAD(P)-dependent epimerase dehydratase family
PIEKEEEF_01495	1.3e-144	lacM	3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97	GH101,GH29	G	beta-galactosidase
PIEKEEEF_01496	0.0	lacL	3.2.1.23		G	Belongs to the glycosyl hydrolase 2 family
PIEKEEEF_01497	5.4e-165	lacR			K	Transcriptional regulator
PIEKEEEF_01498	0.0	lacS			G	Transporter
PIEKEEEF_01499	0.0	lacZ	3.2.1.23		G	-beta-galactosidase
PIEKEEEF_01500	1.1e-220	galK	2.7.1.6		F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIEKEEEF_01501	3.3e-288	galT	2.7.7.12		G	UDP-glucose--hexose-1-phosphate uridylyltransferase
PIEKEEEF_01502	6e-196	galM	5.1.3.3		G	Catalyzes the interconversion of alpha and beta anomers of maltose
PIEKEEEF_01503	5.5e-36
PIEKEEEF_01504	1.1e-159	scrR			K	Periplasmic binding protein domain
PIEKEEEF_01505	2.1e-238	msmE			G	Bacterial extracellular solute-binding protein
PIEKEEEF_01506	4.8e-157	msmF			P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_01507	2.3e-153	msmG			P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_01508	2.8e-210	msmX			P	Belongs to the ABC transporter superfamily
PIEKEEEF_01509	0.0	rafA	3.2.1.22		G	alpha-galactosidase
PIEKEEEF_01510	1e-281	gtfA	2.4.1.7	GH13	G	Sucrose glucosyltransferase
PIEKEEEF_01511	1.5e-109		2.7.6.5		T	Region found in RelA / SpoT proteins
PIEKEEEF_01512	2.1e-104				K	response regulator
PIEKEEEF_01513	2.5e-215	sptS	2.7.13.3		T	Histidine kinase
PIEKEEEF_01514	1.6e-208				EGP	Major facilitator Superfamily
PIEKEEEF_01515	1.9e-68				O	OsmC-like protein
PIEKEEEF_01516	2.6e-94				S	Protein of unknown function (DUF805)
PIEKEEEF_01517	1.5e-63
PIEKEEEF_01518	2e-288
PIEKEEEF_01519	2.8e-08				S	Fic/DOC family
PIEKEEEF_01520	4.5e-49				S	Fic/DOC family
PIEKEEEF_01521	3.3e-275	yjeM			E	Amino Acid
PIEKEEEF_01522	5.2e-223	ackA	2.7.2.1		F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIEKEEEF_01523	1.3e-243	lctO			C	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PIEKEEEF_01525	5.8e-48	argE	3.5.1.18		E	succinyl-diaminopimelate desuccinylase
PIEKEEEF_01526	1.3e-117	dapE	3.5.1.18		E	succinyl-diaminopimelate desuccinylase
PIEKEEEF_01527	9.7e-52				S	Iron-sulfur cluster assembly protein
PIEKEEEF_01528	3.8e-154	sdaAA	4.3.1.17		E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PIEKEEEF_01529	3.4e-123	sdaAB	4.3.1.17		E	Serine dehydratase beta chain
PIEKEEEF_01530	3.7e-45
PIEKEEEF_01531	1.3e-284	lsa			S	ABC transporter
PIEKEEEF_01532	4.4e-110				S	Protein of unknown function (DUF2785)
PIEKEEEF_01533	6.9e-47				S	MazG-like family
PIEKEEEF_01534	1.1e-65
PIEKEEEF_01535	3.7e-118	glsA	3.5.1.2		E	Belongs to the glutaminase family
PIEKEEEF_01536	2.5e-261
PIEKEEEF_01537	5.8e-94	rimL			J	Acetyltransferase (GNAT) domain
PIEKEEEF_01538	3e-134				S	Alpha/beta hydrolase family
PIEKEEEF_01539	9.2e-196	yxaM			EGP	Major facilitator Superfamily
PIEKEEEF_01540	9e-122	fbiB	6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34		S	F420-0:Gamma-glutamyl ligase
PIEKEEEF_01541	9.9e-83				S	AAA domain
PIEKEEEF_01542	5.1e-65		3.6.1.55		F	NUDIX domain
PIEKEEEF_01543	4e-136		2.4.2.3		F	Phosphorylase superfamily
PIEKEEEF_01544	1.3e-142		2.4.2.3		F	Phosphorylase superfamily
PIEKEEEF_01545	3.4e-149	aacC	2.3.1.81		V	Aminoglycoside 3-N-acetyltransferase
PIEKEEEF_01546	4.4e-191	yagE			E	Amino acid permease
PIEKEEEF_01547	1.9e-86		3.4.21.96		S	SLAP domain
PIEKEEEF_01548	4.6e-160	ypjC			S	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEKEEEF_01549	1.1e-225	cca	2.7.7.19, 2.7.7.72		J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIEKEEEF_01550	4.5e-107	hlyIII			S	protein, hemolysin III
PIEKEEEF_01551	2.4e-145	DegV			S	Uncharacterised protein, DegV family COG1307
PIEKEEEF_01552	7.1e-36	yozE			S	Belongs to the UPF0346 family
PIEKEEEF_01553	5.5e-66	yjcE			P	NhaP-type Na H and K H
PIEKEEEF_01554	2.2e-78	yjcE			P	Sodium proton antiporter
PIEKEEEF_01555	2.2e-57	yjcE			P	Sodium proton antiporter
PIEKEEEF_01556	8.1e-154	ylqF			S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIEKEEEF_01557	1e-131	rnhB	3.1.26.4		L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIEKEEEF_01558	2.2e-151	dprA			LU	DNA protecting protein DprA
PIEKEEEF_01559	0.0	topA	5.99.1.2		L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIEKEEEF_01560	3e-248	trmFO	2.1.1.74		J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIEKEEEF_01561	2.5e-140	xerC			D	Phage integrase, N-terminal SAM-like domain
PIEKEEEF_01562	1.3e-88	hslV	3.4.25.2		O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIEKEEEF_01563	3.4e-234	hslU			O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIEKEEEF_01564	4.8e-181	lacX	5.1.3.3		G	Aldose 1-epimerase
PIEKEEEF_01565	2e-39				C	Aldo keto reductase
PIEKEEEF_01566	7.1e-63				M	LysM domain protein
PIEKEEEF_01567	4.3e-152	xerD			L	Phage integrase, N-terminal SAM-like domain
PIEKEEEF_01568	7.9e-67	crcB			U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIEKEEEF_01569	5e-63	crcB			U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIEKEEEF_01570	8.2e-13	mmuM	1.5.1.20, 2.1.1.10		H	homocysteine S-methyltransferase
PIEKEEEF_01571	3.5e-92	mmuP			E	amino acid
PIEKEEEF_01572	2.5e-272	pepV	3.5.1.18		E	dipeptidase PepV
PIEKEEEF_01573	2.1e-93	XK26_02160			C	Pyridoxamine 5'-phosphate oxidase
PIEKEEEF_01574	1.7e-284				E	Amino acid permease
PIEKEEEF_01575	0.0	yaaO	4.1.1.17, 4.1.1.19		E	Orn/Lys/Arg decarboxylase, C-terminal domain
PIEKEEEF_01576	2.3e-245	ynbB	4.4.1.1		P	aluminum resistance
PIEKEEEF_01577	0.0	recQ	3.6.4.12		L	ATP-dependent DNA helicase RecQ
PIEKEEEF_01578	3.4e-82				C	Flavodoxin
PIEKEEEF_01579	0.0	uvrA3			L	excinuclease ABC, A subunit
PIEKEEEF_01580	4.5e-188	mmuM	1.5.1.20, 2.1.1.10		H	homocysteine S-methyltransferase
PIEKEEEF_01581	2e-10	isp2			L	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIEKEEEF_01582	1e-80	XK27_04435	3.5.4.5		J	FR47-like protein
PIEKEEEF_01583	1.4e-36				S	Cytochrome B5
PIEKEEEF_01584	3.9e-167	arbZ			I	Phosphate acyltransferases
PIEKEEEF_01585	5.7e-180	arbY			M	Glycosyl transferase family 8
PIEKEEEF_01586	1.7e-184	arbY			M	Glycosyl transferase family 8
PIEKEEEF_01587	5e-156	arbx			M	Glycosyl transferase family 8
PIEKEEEF_01588	2.4e-149	arbV	2.3.1.51		I	Acyl-transferase
PIEKEEEF_01590	4.9e-34
PIEKEEEF_01592	4.8e-131				K	response regulator
PIEKEEEF_01593	2.2e-305	vicK	2.7.13.3		T	Histidine kinase
PIEKEEEF_01594	1.3e-257	yycH			S	YycH protein
PIEKEEEF_01595	3.4e-149	yycI			S	YycH protein
PIEKEEEF_01596	4.1e-147	vicX	3.1.26.11		S	domain protein
PIEKEEEF_01597	3.3e-151	htrA	3.4.21.107		O	serine protease
PIEKEEEF_01598	1e-81	rlmH	2.1.1.177		J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIEKEEEF_01599	3.2e-103				G	Peptidase_C39 like family
PIEKEEEF_01600	2e-54	pepI	3.4.11.5, 3.5.1.101		E	Releases the N-terminal proline from various substrates
PIEKEEEF_01601	1.9e-112	pepI	3.4.11.5, 3.5.1.101		E	Releases the N-terminal proline from various substrates
PIEKEEEF_01602	1.1e-76				P	Cobalt transport protein
PIEKEEEF_01603	6.3e-249	cbiO1			S	ABC transporter, ATP-binding protein
PIEKEEEF_01604	7.9e-174				K	helix_turn_helix, arabinose operon control protein
PIEKEEEF_01605	7.5e-158	htpX			O	Belongs to the peptidase M48B family
PIEKEEEF_01606	1.1e-95	lemA			S	LemA family
PIEKEEEF_01607	1.5e-192	ybiR			P	Citrate transporter
PIEKEEEF_01608	5.9e-70				S	Iron-sulphur cluster biosynthesis
PIEKEEEF_01609	3.7e-310	glpQ	3.1.4.46		C	Membrane domain of glycerophosphoryl diester phosphodiesterase
PIEKEEEF_01610	1.2e-17
PIEKEEEF_01611	6.9e-100
PIEKEEEF_01613	6.8e-216	ydaM			M	Glycosyl transferase
PIEKEEEF_01614	4.1e-174				G	Glycosyl hydrolases family 8
PIEKEEEF_01615	1e-119	yfbR			S	HD containing hydrolase-like enzyme
PIEKEEEF_01616	9.9e-160				L	HNH nucleases
PIEKEEEF_01617	1.6e-139				S	Protein of unknown function (DUF805)
PIEKEEEF_01618	2.8e-137	glnQ			E	ABC transporter, ATP-binding protein
PIEKEEEF_01619	1.2e-291	glnP			P	ABC transporter permease
PIEKEEEF_01620	2.6e-120	mpg	3.2.2.21		L	Belongs to the DNA glycosylase MPG family
PIEKEEEF_01621	8.2e-63	yeaO			S	Protein of unknown function, DUF488
PIEKEEEF_01622	2.2e-124	terC			P	membrane
PIEKEEEF_01623	1.7e-55	ogt	2.1.1.63		L	6-O-methylguanine DNA methyltransferase, DNA binding domain
PIEKEEEF_01624	3.9e-133	cobB			K	SIR2 family
PIEKEEEF_01625	5.5e-83
PIEKEEEF_01626	2.9e-284	cls			I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIEKEEEF_01627	5.5e-180				S	Alpha/beta hydrolase of unknown function (DUF915)
PIEKEEEF_01628	2.6e-119	rnhA	3.1.26.4		L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIEKEEEF_01629	6.8e-141	ypuA			S	Protein of unknown function (DUF1002)
PIEKEEEF_01630	1.9e-160	epsV	2.7.8.12		S	glycosyl transferase family 2
PIEKEEEF_01631	3.1e-124				S	Alpha/beta hydrolase family
PIEKEEEF_01632	3e-116				GM	NmrA-like family
PIEKEEEF_01633	1.8e-44				K	Putative ATP-dependent DNA helicase recG C-terminal
PIEKEEEF_01634	6.9e-71	ytlR	2.7.1.91		I	Diacylglycerol kinase catalytic domain
PIEKEEEF_01635	1.3e-82	ytlR	2.7.1.91		I	Diacylglycerol kinase catalytic domain
PIEKEEEF_01636	3.5e-294				L	Nuclease-related domain
PIEKEEEF_01637	0.0	recD2	3.1.11.5		L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIEKEEEF_01638	8.3e-106				S	Repeat protein
PIEKEEEF_01639	3.9e-127	pgm6	5.4.2.11, 5.4.2.12		G	Phosphoglycerate mutase family
PIEKEEEF_01640	1.3e-220	mnmA	2.8.1.13		J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIEKEEEF_01641	2.2e-57	XK27_04120			S	Putative amino acid metabolism
PIEKEEEF_01642	6e-216	iscS	2.8.1.7		E	Aminotransferase class V
PIEKEEEF_01643	3.5e-126	mtnN	3.2.2.9		E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIEKEEEF_01644	2.1e-38
PIEKEEEF_01645	9.8e-103	nudF	3.6.1.13		L	ADP-ribose pyrophosphatase
PIEKEEEF_01646	3.6e-31	cspA			K	'Cold-shock' DNA-binding domain
PIEKEEEF_01647	0.0	ileS	6.1.1.5		J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIEKEEEF_01648	2.8e-74	gpsB			D	DivIVA domain protein
PIEKEEEF_01649	2e-149	ylmH			S	S4 domain protein
PIEKEEEF_01650	1.7e-45	yggT			S	YGGT family
PIEKEEEF_01651	7.3e-74	sepF			D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIEKEEEF_01652	1.7e-206	ftsZ			D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIEKEEEF_01653	7.7e-247	ftsA			D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIEKEEEF_01654	4.5e-152	divIB			D	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIEKEEEF_01655	4.4e-208	murG	2.4.1.227, 6.3.2.8	GT28	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIEKEEEF_01656	5e-262	murD	6.3.2.9		M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIEKEEEF_01657	1.5e-175	mraY	2.7.8.13		M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIEKEEEF_01658	0.0	ftsI	3.4.16.4		M	Penicillin-binding Protein
PIEKEEEF_01659	1.8e-54	ftsL			D	Cell division protein FtsL
PIEKEEEF_01660	3.8e-176	rsmH	2.1.1.199		J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIEKEEEF_01661	6.3e-78	mraZ			K	Belongs to the MraZ family
PIEKEEEF_01662	6.4e-54				S	Protein of unknown function (DUF3397)
PIEKEEEF_01664	2.7e-94	mreD
PIEKEEEF_01665	2e-147	mreC			M	Involved in formation and maintenance of cell shape
PIEKEEEF_01666	2.4e-176	mreB			D	cell shape determining protein MreB
PIEKEEEF_01667	2.3e-108	radC			L	DNA repair protein
PIEKEEEF_01668	5.7e-126				S	Haloacid dehalogenase-like hydrolase
PIEKEEEF_01669	1.5e-239	folC	6.3.2.12, 6.3.2.17		H	Belongs to the folylpolyglutamate synthase family
PIEKEEEF_01670	0.0	valS	6.1.1.9		J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIEKEEEF_01671	1.3e-51
PIEKEEEF_01672	1e-133				S	AAA domain, putative AbiEii toxin, Type IV TA system
PIEKEEEF_01673	0.0		3.6.3.8		P	P-type ATPase
PIEKEEEF_01675	2.9e-44
PIEKEEEF_01676	2.2e-63				S	Protein of unknown function (DUF3990)
PIEKEEEF_01677	1e-170	yfdH	2.4.2.53	GT2	M	Glycosyltransferase, group 2 family protein
PIEKEEEF_01678	2.1e-65		2.4.1.83	GT2	S	GtrA-like protein
PIEKEEEF_01679	4.7e-43		3.6.4.12		S	PD-(D/E)XK nuclease family transposase
PIEKEEEF_01680	5.2e-122	rsuA	5.4.99.19, 5.4.99.22		J	Belongs to the pseudouridine synthase RsuA family
PIEKEEEF_01681	1.9e-10
PIEKEEEF_01682	2.7e-49
PIEKEEEF_01684	2.7e-74				M	LysM domain
PIEKEEEF_01685	5.5e-87
PIEKEEEF_01686	3.2e-135	yjjG	3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2		S	Haloacid dehalogenase-like hydrolase
PIEKEEEF_01687	2.2e-148	ropB			K	Helix-turn-helix domain
PIEKEEEF_01688	3e-282				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_01689	3.6e-177	ABC-SBP			S	ABC transporter
PIEKEEEF_01690	5.6e-121	XK27_08840			U	Belongs to the binding-protein-dependent transport system permease family
PIEKEEEF_01691	1.1e-136	XK27_08845			S	ABC transporter, ATP-binding protein
PIEKEEEF_01692	1.5e-247				G	Major Facilitator
PIEKEEEF_01693	4.1e-18
PIEKEEEF_01694	4e-104		3.1.1.5		E	GDSL-like Lipase/Acylhydrolase
PIEKEEEF_01695	4.9e-177				K	AI-2E family transporter
PIEKEEEF_01696	0.0	oppA			E	ABC transporter substrate-binding protein
PIEKEEEF_01697	0.0	rtpR	1.1.98.6, 1.17.4.1, 1.17.4.2		F	ribonucleoside-triphosphate reductase activity
PIEKEEEF_01698	1.1e-41				S	Domain of unknown function (DUF4430)
PIEKEEEF_01699	2.7e-24				S	Domain of unknown function (DUF4430)
PIEKEEEF_01700	4.7e-54				S	ECF transporter, substrate-specific component
PIEKEEEF_01701	2e-79	yvqK	1.2.1.88, 1.5.5.2, 2.5.1.17		S	cob(I)alamin adenosyltransferase
PIEKEEEF_01702	6.7e-147				S	Putative ABC-transporter type IV
PIEKEEEF_01703	3.8e-07				S	LPXTG cell wall anchor motif
PIEKEEEF_01704	6.2e-96	ybaT			E	Amino acid permease
PIEKEEEF_01706	1.2e-126
PIEKEEEF_01708	6.5e-64				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_01710	9.2e-119	yhiD			S	MgtC family
PIEKEEEF_01711	9.1e-231				I	Protein of unknown function (DUF2974)
PIEKEEEF_01712	3.5e-15				S	Transglycosylase associated protein
PIEKEEEF_01714	1.5e-166	scrK	2.7.1.2, 2.7.1.4		GK	ROK family
PIEKEEEF_01715	6.5e-136				V	ABC transporter transmembrane region
PIEKEEEF_01716	5.2e-170	degV			S	DegV family
PIEKEEEF_01717	2.3e-165	phnD			P	ABC transporter, phosphonate, periplasmic substrate-binding protein
PIEKEEEF_01718	6.7e-254	dnaB	3.6.4.12		L	Participates in initiation and elongation during chromosome replication
PIEKEEEF_01719	5.7e-69	rplI			J	Binds to the 23S rRNA
PIEKEEEF_01720	0.0	yybT			T	signaling protein consisting of a modified GGDEF domain and a DHH domain
PIEKEEEF_01721	1.8e-201				S	SLAP domain
PIEKEEEF_01722	1.9e-170				S	Bacteriocin helveticin-J
PIEKEEEF_01723	4.4e-101				S	ECF transporter, substrate-specific component
PIEKEEEF_01724	0.0	ppc	4.1.1.31		H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PIEKEEEF_01725	0.0	macB_3			V	ABC transporter, ATP-binding protein
PIEKEEEF_01726	1.6e-194				S	DUF218 domain
PIEKEEEF_01727	8.3e-122				S	CAAX protease self-immunity
PIEKEEEF_01728	1.8e-111	ropB			K	Transcriptional regulator
PIEKEEEF_01729	1.7e-155				EGP	Major facilitator Superfamily
PIEKEEEF_01730	1.6e-50
PIEKEEEF_01731	5.5e-158	mutR			K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01732	1.5e-278				V	ABC transporter transmembrane region
PIEKEEEF_01733	5.7e-206	napA			P	Sodium/hydrogen exchanger family
PIEKEEEF_01734	5.7e-62
PIEKEEEF_01735	0.0	cadA			P	P-type ATPase
PIEKEEEF_01736	3.9e-81	ykuL			S	(CBS) domain
PIEKEEEF_01737	1.1e-206	ywhK			S	Membrane
PIEKEEEF_01738	4.1e-44
PIEKEEEF_01739	5.2e-19				S	D-Ala-teichoic acid biosynthesis protein
PIEKEEEF_01740	2.1e-285	dltA	6.1.1.13		H	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIEKEEEF_01741	1.6e-238	dltB			M	MBOAT, membrane-bound O-acyltransferase family
PIEKEEEF_01742	1.7e-35	dltC	6.1.1.13		J	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIEKEEEF_01743	3e-248	dltD			M	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIEKEEEF_01744	7.6e-177	pbpX2			V	Beta-lactamase
PIEKEEEF_01745	7.9e-134				S	Protein of unknown function (DUF975)
PIEKEEEF_01746	2.7e-137	lysA2			M	Glycosyl hydrolases family 25
PIEKEEEF_01747	3.9e-290	ytgP			S	Polysaccharide biosynthesis protein
PIEKEEEF_01748	1.9e-36
PIEKEEEF_01749	0.0	XK27_06780			V	ABC transporter permease
PIEKEEEF_01750	5.1e-125	XK27_06785			V	ABC transporter, ATP-binding protein
PIEKEEEF_01751	2.6e-239	pts13C			G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEKEEEF_01752	2.6e-166				S	Alpha/beta hydrolase of unknown function (DUF915)
PIEKEEEF_01753	0.0	clpE			O	AAA domain (Cdc48 subfamily)
PIEKEEEF_01754	2.1e-114		3.6.1.27		I	Acid phosphatase homologues
PIEKEEEF_01755	1.9e-80	yvbK	3.1.3.25		K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIEKEEEF_01756	1.4e-115	lacA	2.3.1.79		S	Transferase hexapeptide repeat
PIEKEEEF_01757	2.7e-203	pbpX1			V	Beta-lactamase
PIEKEEEF_01758	1.8e-97	pdxK	2.7.1.35		H	Phosphomethylpyrimidine kinase
PIEKEEEF_01759	2.2e-94				S	ECF-type riboflavin transporter, S component
PIEKEEEF_01760	9.9e-230				S	Putative peptidoglycan binding domain
PIEKEEEF_01761	8.1e-84				K	Acetyltransferase (GNAT) domain
PIEKEEEF_01762	3.2e-250	pepT2	3.4.11.14, 3.4.11.4		E	Cleaves the N-terminal amino acid of tripeptides
PIEKEEEF_01763	4.3e-191	yrvN			L	AAA C-terminal domain
PIEKEEEF_01764	2.8e-64	spxA_2	1.20.4.1		K	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIEKEEEF_01765	1.2e-298	treB			G	phosphotransferase system
PIEKEEEF_01766	1.2e-100	treR			K	UTRA
PIEKEEEF_01767	3.4e-289	treC	3.2.1.93	GH13	G	Alpha amylase, catalytic domain protein
PIEKEEEF_01768	4.4e-18
PIEKEEEF_01769	9.5e-239				G	Bacterial extracellular solute-binding protein
PIEKEEEF_01770	1.3e-60	pdxH			S	Pyridoxamine 5'-phosphate oxidase
PIEKEEEF_01771	3.8e-237	XK27_01810			S	Calcineurin-like phosphoesterase
PIEKEEEF_01773	0.0				S	SLAP domain
PIEKEEEF_01774	0.0	hsdR	3.1.21.3		L	DEAD/DEAH box helicase
PIEKEEEF_01775	2.4e-212				S	AAA domain, putative AbiEii toxin, Type IV TA system
PIEKEEEF_01776	5.3e-27	hsdM	2.1.1.72		V	type I restriction-modification system
PIEKEEEF_01777	1.1e-234	hsdM	2.1.1.72		V	type I restriction-modification system
PIEKEEEF_01778	5.4e-124	hsdS	3.1.21.3		V	Type I restriction modification DNA specificity domain
PIEKEEEF_01780	1.8e-31
PIEKEEEF_01782	9e-07
PIEKEEEF_01783	7.8e-72
PIEKEEEF_01786	6.3e-47				S	Sel1-like repeats.
PIEKEEEF_01787	5.9e-79				S	HIRAN
PIEKEEEF_01788	4.7e-31
PIEKEEEF_01789	1.7e-116	lepB	3.4.21.89		U	Belongs to the peptidase S26 family
PIEKEEEF_01790	3.1e-232	cycA			E	Amino acid permease
PIEKEEEF_01791	2.1e-244	yifK			E	Amino acid permease
PIEKEEEF_01792	3.1e-177				S	PFAM Archaeal ATPase
PIEKEEEF_01793	3.4e-140	puuD			S	peptidase C26
PIEKEEEF_01794	8.8e-230	steT_1			E	amino acid
PIEKEEEF_01795	1.3e-190	asnA	6.3.1.1		F	aspartate--ammonia ligase
PIEKEEEF_01796	1.5e-205		4.2.1.126		S	Bacterial protein of unknown function (DUF871)
PIEKEEEF_01799	7e-189	guaC	1.1.1.205, 1.7.1.7		F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIEKEEEF_01800	6.4e-251	purA	6.3.4.4		F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIEKEEEF_01801	2.8e-246	purB	4.3.2.2		F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIEKEEEF_01802	1.7e-18	hicA			S	HicA toxin of bacterial toxin-antitoxin,
PIEKEEEF_01803	9.2e-56				S	protein encoded in hypervariable junctions of pilus gene clusters
PIEKEEEF_01805	1.1e-118	ropB			K	Helix-turn-helix domain
PIEKEEEF_01806	2.3e-39				S	Bacteriocin (Lactococcin_972)
PIEKEEEF_01807	2.7e-277
PIEKEEEF_01808	1.2e-99				V	ABC transporter
PIEKEEEF_01809	7.9e-25				S	Protein conserved in bacteria
PIEKEEEF_01810	5.1e-57
PIEKEEEF_01811	1.1e-86
PIEKEEEF_01812	1.2e-263	yheS_2			S	ATPases associated with a variety of cellular activities
PIEKEEEF_01813	7.5e-186	XK27_05540			S	DUF218 domain
PIEKEEEF_01814	1.4e-110
PIEKEEEF_01815	2.5e-107
PIEKEEEF_01816	2.5e-140	yicL			EG	EamA-like transporter family
PIEKEEEF_01817	5.3e-167				EG	EamA-like transporter family
PIEKEEEF_01818	1.7e-157				EG	EamA-like transporter family
PIEKEEEF_01819	3.2e-38
PIEKEEEF_01822	9.6e-158
PIEKEEEF_01824	6.9e-81				M	NlpC/P60 family
PIEKEEEF_01825	1.2e-131	cobQ			S	glutamine amidotransferase
PIEKEEEF_01826	3.2e-63				L	RelB antitoxin
PIEKEEEF_01827	4.3e-77				V	ABC transporter transmembrane region
PIEKEEEF_01828	1.4e-69	def2	3.5.1.31, 3.5.1.88		J	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PIEKEEEF_01829	2e-225				N	Uncharacterized conserved protein (DUF2075)
PIEKEEEF_01830	6.2e-205	pbpX1			V	Beta-lactamase
PIEKEEEF_01831	0.0				L	Helicase C-terminal domain protein
PIEKEEEF_01832	1.7e-273				E	amino acid
PIEKEEEF_01833	2e-157	xth	3.1.11.2		L	exodeoxyribonuclease III
PIEKEEEF_01835	9e-192	ldhA	1.1.1.28		C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIEKEEEF_01836	3e-80	birA	6.3.4.15		H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIEKEEEF_01837	1.9e-122	fabI	1.3.1.10, 1.3.1.9		I	Enoyl- acyl-carrier-protein reductase NADH
PIEKEEEF_01838	1.1e-128	accA	2.1.3.15, 6.4.1.2		I	alpha subunit
PIEKEEEF_01839	3.3e-139	accD	2.1.3.15, 6.4.1.2		I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIEKEEEF_01840	3.3e-237	accC	6.3.4.14, 6.4.1.2		I	Acetyl-CoA carboxylase biotin carboxylase subunit
PIEKEEEF_01841	9.2e-61	fabZ	3.5.1.108, 4.2.1.59		I	FabA-like domain
PIEKEEEF_01842	2.2e-49	accB	2.3.1.12, 4.1.1.3		I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIEKEEEF_01843	3.1e-210	fabF	2.3.1.179		I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIEKEEEF_01844	2.9e-107				IQ	reductase
PIEKEEEF_01845	7.5e-140	fabD	2.3.1.39		I	Malonyl CoA-acyl carrier protein transacylase
PIEKEEEF_01846	2.1e-30	acpP			IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIEKEEEF_01847	6.3e-134	fabH	2.3.1.180		I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIEKEEEF_01848	1.3e-48		4.2.1.59		I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PIEKEEEF_01849	1.6e-73	marR			K	Transcriptional regulator, MarR family
PIEKEEEF_01850	7.6e-80
PIEKEEEF_01853	1.9e-35		2.7.7.73, 2.7.7.80		H	ThiF family
PIEKEEEF_01854	3.6e-09				M	Kdo2-lipid A biosynthetic process
PIEKEEEF_01855	4.9e-133				EGP	Major facilitator Superfamily
PIEKEEEF_01856	1.5e-149		3.1.3.102, 3.1.3.104		S	haloacid dehalogenase-like hydrolase
PIEKEEEF_01857	0.0	tetP			J	elongation factor G
PIEKEEEF_01858	1.1e-86				K	Helix-turn-helix domain
PIEKEEEF_01859	8.9e-181				S	Domain of unknown function (DUF389)
PIEKEEEF_01860	3.8e-88
PIEKEEEF_01861	0.0	thrS	6.1.1.3		J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIEKEEEF_01862	8.1e-168	dnaI			L	Primosomal protein DnaI
PIEKEEEF_01863	3e-251	dnaB			L	Replication initiation and membrane attachment
PIEKEEEF_01864	3.5e-82	nrdR			K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIEKEEEF_01865	1.3e-105	coaE	2.7.1.24		F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIEKEEEF_01866	6.1e-154	fpg	3.2.2.23, 4.2.99.18		L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIEKEEEF_01867	0.0	polA	2.7.7.7		L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIEKEEEF_01868	3.3e-42
PIEKEEEF_01869	7.8e-149	levD			G	PTS system mannose/fructose/sorbose family IID component
PIEKEEEF_01870	2.4e-137				M	PTS system sorbose-specific iic component
PIEKEEEF_01871	2.4e-89		2.7.1.191		G	PTS system sorbose subfamily IIB component
PIEKEEEF_01872	6.5e-62	levA			G	PTS system fructose IIA component
PIEKEEEF_01873	6e-92	rbsB			G	Periplasmic binding protein domain
PIEKEEEF_01874	2.3e-115	baeS			F	Sensor histidine kinase
PIEKEEEF_01875	3.7e-96	baeR			K	helix_turn_helix, Lux Regulon
PIEKEEEF_01876	8.6e-107				G	Bacterial extracellular solute-binding protein
PIEKEEEF_01878	3.7e-115	deoC	4.1.2.4		F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIEKEEEF_01879	1.9e-71	yegW			K	UTRA
PIEKEEEF_01880	5e-117	tal	2.2.1.2		H	Transaldolase/Fructose-6-phosphate aldolase
PIEKEEEF_01881	2.9e-16				K	Transcriptional regulator, TetR family
PIEKEEEF_01882	1.5e-211				M	Glycosyl hydrolases family 25
PIEKEEEF_01883	2.3e-110	XK27_00160			S	Domain of unknown function (DUF5052)
PIEKEEEF_01884	4.1e-67
PIEKEEEF_01885	5.4e-203	xerS			L	Belongs to the 'phage' integrase family
PIEKEEEF_01886	1.5e-304	mutS2			L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIEKEEEF_01887	1.3e-159	degV			S	EDD domain protein, DegV family
PIEKEEEF_01888	1.1e-66
PIEKEEEF_01889	0.0	FbpA			K	Fibronectin-binding protein
PIEKEEEF_01890	0.0	carB1	6.3.5.5		F	Carbamoyl-phosphate synthase
PIEKEEEF_01891	4.6e-199	carA	6.3.5.5		F	Carbamoyl-phosphate synthetase glutamine chain
PIEKEEEF_01892	1.6e-168	rluD	5.4.99.23		J	Responsible for synthesis of pseudouridine from uracil
PIEKEEEF_01893	1.4e-78	lspA	3.4.23.36		MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIEKEEEF_01894	1.4e-287	fhs	6.3.4.3		F	Belongs to the formate--tetrahydrofolate ligase family
PIEKEEEF_01895	7.2e-45
PIEKEEEF_01896	4.4e-158	psd	4.1.1.65		I	Belongs to the phosphatidylserine decarboxylase family
PIEKEEEF_01897	2e-178				D	nuclear chromosome segregation
PIEKEEEF_01898	1.3e-177				S	Phage Mu protein F like protein
PIEKEEEF_01899	3.1e-262				S	Phage portal protein, SPP1 Gp6-like
PIEKEEEF_01900	1.2e-211	ps334			S	Terminase-like family
PIEKEEEF_01901	1.8e-42				L	NUMOD4 motif
PIEKEEEF_01902	1.3e-50	ps333			L	Terminase small subunit
PIEKEEEF_01904	7.5e-26	arpU			S	Phage transcriptional regulator, ArpU family
PIEKEEEF_01907	4.5e-46				S	VRR_NUC
PIEKEEEF_01910	1.2e-19
PIEKEEEF_01914	9.6e-31				S	Domain of Unknown Function (DUF1599)
PIEKEEEF_01917	1e-211				S	Virulence-associated protein E
PIEKEEEF_01918	4.4e-125				S	Bifunctional DNA primase/polymerase, N-terminal
PIEKEEEF_01919	6.3e-32
PIEKEEEF_01921	3.4e-42
PIEKEEEF_01922	1.5e-82				L	AAA domain
PIEKEEEF_01924	2.1e-193	res			L	Helicase C-terminal domain protein
PIEKEEEF_01925	6.6e-35				L	NUMOD4 motif
PIEKEEEF_01926	5.6e-25
PIEKEEEF_01928	2.6e-64				S	Siphovirus Gp157
PIEKEEEF_01931	9.5e-49
PIEKEEEF_01934	8.2e-26
PIEKEEEF_01935	3.4e-117				K	ORF6N domain
PIEKEEEF_01936	4.2e-11
PIEKEEEF_01937	7.4e-45	ps115			K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01938	8.5e-69	xkdA			E	Zn peptidase
PIEKEEEF_01939	2.3e-52				S	Domain of Unknown Function with PDB structure (DUF3862)
PIEKEEEF_01941	2.2e-277				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_01942	2e-291				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_01943	1.7e-148				S	haloacid dehalogenase-like hydrolase
PIEKEEEF_01944	2.6e-52
PIEKEEEF_01945	1.9e-37
PIEKEEEF_01946	4.5e-42				S	Alpha beta hydrolase
PIEKEEEF_01947	0.0	pepX	3.4.14.11		E	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIEKEEEF_01948	1.4e-80	msrB	1.8.4.11, 1.8.4.12		O	peptide methionine sulfoxide reductase
PIEKEEEF_01949	7.1e-46
PIEKEEEF_01950	3.1e-148	glcU			U	sugar transport
PIEKEEEF_01951	6.4e-250	lctP			C	L-lactate permease
PIEKEEEF_01952	0.0	carB	6.3.5.5		F	Carbamoyl-phosphate synthase
PIEKEEEF_01953	1.2e-210	carA	6.3.5.5		F	Carbamoyl-phosphate synthetase glutamine chain
PIEKEEEF_01954	4e-245	pyrC	3.5.2.3		F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIEKEEEF_01955	1.2e-182	pyrB	2.1.3.2		F	Belongs to the ATCase OTCase family
PIEKEEEF_01956	4.6e-94	pyrR	2.4.2.9		F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIEKEEEF_01957	4.5e-166	pyrD	1.3.1.14, 1.3.98.1		F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIEKEEEF_01959	3.7e-13				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01960	1.3e-58				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01961	3.2e-45				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_01962	2.8e-19
PIEKEEEF_01963	9.6e-152	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17		H	Phosphomethylpyrimidine kinase
PIEKEEEF_01964	1e-292	glpK	2.7.1.30		F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIEKEEEF_01965	6.3e-145	ptp2	3.1.3.48		T	Tyrosine phosphatase family
PIEKEEEF_01966	1.1e-178	yvdE			K	helix_turn _helix lactose operon repressor
PIEKEEEF_01967	1.1e-214	ackA	2.7.2.1		F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIEKEEEF_01968	1.2e-76				S	PAS domain
PIEKEEEF_01969	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	Alpha amylase, catalytic domain
PIEKEEEF_01970	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	Belongs to the glycosyl hydrolase 13 family
PIEKEEEF_01971	0.0	map2	2.4.1.8	GH65	G	hydrolase, family 65, central catalytic
PIEKEEEF_01972	4e-116	pgmB	2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6	GH37,GH65	S	beta-phosphoglucomutase
PIEKEEEF_01973	9.8e-208	msmX			P	Belongs to the ABC transporter superfamily
PIEKEEEF_01974	3.8e-213	malE			G	Bacterial extracellular solute-binding protein
PIEKEEEF_01975	1.1e-250	malF			P	Binding-protein-dependent transport system inner membrane component
PIEKEEEF_01976	4.4e-147	malG			P	ABC transporter permease
PIEKEEEF_01977	0.0	rnjA			J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIEKEEEF_01978	9.3e-33	ykzG			S	Belongs to the UPF0356 family
PIEKEEEF_01979	4e-101	def	3.5.1.31, 3.5.1.88		J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIEKEEEF_01980	0.0	typA			T	GTP-binding protein TypA
PIEKEEEF_01981	7.7e-211	ftsW			D	Belongs to the SEDS family
PIEKEEEF_01982	1.5e-53	ylbG			S	Uncharacterized protein conserved in bacteria (DUF2129)
PIEKEEEF_01983	4.5e-97	rsmD	2.1.1.171		L	RNA methyltransferase, RsmD family
PIEKEEEF_01984	3.6e-82	coaD	2.7.7.3		H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIEKEEEF_01985	6.2e-188	ylbL			T	Belongs to the peptidase S16 family
PIEKEEEF_01986	9.1e-79	comEA			L	Competence protein ComEA
PIEKEEEF_01987	0.0	comEC			S	Competence protein ComEC
PIEKEEEF_01988	7.5e-175	holA	2.7.7.7		L	DNA polymerase III delta subunit
PIEKEEEF_01989	6.7e-35	rpsT			J	Binds directly to 16S ribosomal RNA
PIEKEEEF_01990	1.6e-42	rpsO			J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIEKEEEF_01991	0.0	rnjB			J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIEKEEEF_01992	8.3e-151
PIEKEEEF_01995	6e-29	mloB			K	Putative ATP-dependent DNA helicase recG C-terminal
PIEKEEEF_01996	1.1e-246	lctP			C	L-lactate permease
PIEKEEEF_01997	7.9e-127	znuB			U	ABC 3 transport family
PIEKEEEF_01998	1e-108	fhuC			P	ABC transporter
PIEKEEEF_01999	3e-138	psaA			P	Belongs to the bacterial solute-binding protein 9 family
PIEKEEEF_02000	8.9e-44				K	helix_turn_helix, Arsenical Resistance Operon Repressor
PIEKEEEF_02001	0.0	fruA	2.7.1.202, 2.7.1.204		GT	Phosphotransferase System
PIEKEEEF_02002	2.2e-168	pfkB	2.7.1.11, 2.7.1.56		H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PIEKEEEF_02003	1.8e-136	fruR			K	DeoR C terminal sensor domain
PIEKEEEF_02004	1.4e-218	natB			CP	ABC-2 family transporter protein
PIEKEEEF_02005	7e-164	natA			S	ABC transporter, ATP-binding protein
PIEKEEEF_02006	4.3e-36
PIEKEEEF_02007	4.9e-67
PIEKEEEF_02008	2.8e-25
PIEKEEEF_02009	8.2e-31	yozG			K	Transcriptional regulator
PIEKEEEF_02010	1e-80
PIEKEEEF_02011	2.7e-22
PIEKEEEF_02012	3.8e-31
PIEKEEEF_02013	8.6e-184		3.6.4.12		K	Putative ATP-dependent DNA helicase recG C-terminal
PIEKEEEF_02014	5.5e-228	thiI	2.8.1.4		H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIEKEEEF_02015	2.1e-213	iscS2	2.8.1.7		E	Aminotransferase class V
PIEKEEEF_02016	1.6e-289	ezrA			D	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIEKEEEF_02017	1.4e-110	rpsD			J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIEKEEEF_02018	9.9e-85	yueI			S	Protein of unknown function (DUF1694)
PIEKEEEF_02019	7.4e-239	rarA			L	recombination factor protein RarA
PIEKEEEF_02020	8.4e-39
PIEKEEEF_02021	9.8e-77	usp6			T	universal stress protein
PIEKEEEF_02022	0.0	pulA	3.2.1.41	CBM48,GH13	G	belongs to the glycosyl hydrolase 13 family
PIEKEEEF_02024	2.2e-55				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_02026	8.4e-39				L	PFAM transposase, IS4 family protein
PIEKEEEF_02027	4e-149				V	Abi-like protein
PIEKEEEF_02028	5.5e-16				S	Helix-turn-helix domain
PIEKEEEF_02029	6.3e-112				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_02030	2.1e-56				S	SIR2-like domain
PIEKEEEF_02031	9.3e-99				S	Domain of unknown function DUF87
PIEKEEEF_02033	2.6e-74				L	COG2826 Transposase and inactivated derivatives, IS30 family
PIEKEEEF_02034	6.4e-79				L	COG2826 Transposase and inactivated derivatives, IS30 family
PIEKEEEF_02035	1.8e-25
PIEKEEEF_02036	8e-07
PIEKEEEF_02037	1.8e-22
PIEKEEEF_02039	7.6e-117				S	Peptidase family M23
PIEKEEEF_02040	2.9e-107	msrA	1.8.4.11, 1.8.4.12		O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIEKEEEF_02042	4.6e-160	yitT			S	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEKEEEF_02043	6.8e-110
PIEKEEEF_02044	5e-159	thrB	2.7.1.39		F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIEKEEEF_02045	5e-221	hom	1.1.1.3, 2.7.2.4		E	homoserine dehydrogenase
PIEKEEEF_02046	2.1e-282	thrC	4.2.3.1		E	Threonine synthase
PIEKEEEF_02047	4e-122	lysC	2.7.2.4		E	Belongs to the aspartokinase family
PIEKEEEF_02048	1.7e-128	lysC	2.7.2.4		E	Belongs to the aspartokinase family
PIEKEEEF_02049	1.5e-103	pgm3	5.4.2.11		G	Histidine phosphatase superfamily (branch 1)
PIEKEEEF_02061	1.8e-223	mgs	2.4.1.337	GT4	M	Glycosyl transferase 4-like domain
PIEKEEEF_02062	2.6e-202	cpoA		GT4	M	Glycosyltransferase, group 1 family protein
PIEKEEEF_02063	2e-178	mprF			S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIEKEEEF_02064	0.0	ltaS	2.7.8.20		M	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIEKEEEF_02065	1.7e-29	secG			U	Preprotein translocase
PIEKEEEF_02066	0.0	rnr			J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIEKEEEF_02067	5.1e-78	smpB			J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIEKEEEF_02068	0.0	cas3			L	CRISPR-associated helicase cas3
PIEKEEEF_02069	0.0	casA			L	the current gene model (or a revised gene model) may contain a frame shift
PIEKEEEF_02070	3.5e-106	casB			S	CRISPR-associated protein Cse2 (CRISPR_cse2)
PIEKEEEF_02071	7e-198	casC			L	CT1975-like protein
PIEKEEEF_02072	3.7e-131	casD			S	CRISPR-associated protein (Cas_Cas5)
PIEKEEEF_02073	1.3e-122	casE			S	CRISPR_assoc
PIEKEEEF_02074	1.3e-173	cas1			L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PIEKEEEF_02075	6.3e-154	cas2	2.7.7.7		L	CRISPR-associated protein (Cas_Cas2CT1978)
PIEKEEEF_02076	7.1e-66	ftsZ			M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PIEKEEEF_02077	2.3e-25
PIEKEEEF_02078	1.1e-59				L	PFAM IS66 Orf2 family protein
PIEKEEEF_02079	3.2e-240				L	Transposase IS66 family
PIEKEEEF_02080	0.0	fruA	3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80	GH13,GH32	G	Beta-fructosidases (levanase invertase)
PIEKEEEF_02081	1.1e-94	MA20_25245			K	Acetyltransferase (GNAT) domain
PIEKEEEF_02086	1.7e-260	emrY			EGP	Major facilitator Superfamily
PIEKEEEF_02087	2e-91	yxdD			K	Bacterial regulatory proteins, tetR family
PIEKEEEF_02088	0.0		4.2.1.53		S	Myosin-crossreactive antigen
PIEKEEEF_02089	2.1e-34				S	Domain of unknown function (DUF4417)
PIEKEEEF_02090	8.2e-19
PIEKEEEF_02091	6.8e-20
PIEKEEEF_02092	8.8e-72				K	LysR substrate binding domain
PIEKEEEF_02093	9e-98
PIEKEEEF_02094	3e-119	VY92_08690	5.3.1.32		G	Antibiotic biosynthesis monooxygenase
PIEKEEEF_02095	8e-95
PIEKEEEF_02096	3.4e-286				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_02097	2.4e-284				V	ABC-type multidrug transport system, ATPase and permease components
PIEKEEEF_02099	4.9e-16	lysR7			K	LysR substrate binding domain
PIEKEEEF_02100	1.8e-62				K	Bacterial regulatory helix-turn-helix protein, lysR family
PIEKEEEF_02101	2.1e-144	ptlF			S	KR domain
PIEKEEEF_02102	6.9e-164	ptlF			S	KR domain
PIEKEEEF_02103	3.5e-117	drgA			C	nitroreductase
PIEKEEEF_02106	3.1e-19				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_02107	7.4e-49				LO	Psort location Cytoplasmic, score 8.87
PIEKEEEF_02108	5.3e-67				L	An automated process has identified a potential problem with this gene model
PIEKEEEF_02109	6.2e-25				G	phosphotransferase system, EIIB
PIEKEEEF_02110	8.4e-36				G	phosphotransferase system, EIIB
PIEKEEEF_02111	1.3e-72				L	Transposase DDE domain
PIEKEEEF_02112	0.0	XK27_00340	3.1.3.5		F	Belongs to the 5'-nucleotidase family
PIEKEEEF_02113	5.6e-51				V	Abi-like protein
PIEKEEEF_02114	1.1e-46				V	Abi-like protein
PIEKEEEF_02115	1.8e-186				G	Transmembrane secretion effector
PIEKEEEF_02116	7.4e-81				V	ABC transporter transmembrane region
PIEKEEEF_02117	1.4e-38				V	ABC transporter transmembrane region
PIEKEEEF_02118	1e-179
PIEKEEEF_02119	3.1e-104		3.1.4.37		S	AAA domain
PIEKEEEF_02120	9.7e-74				S	Sel1-like repeats.
PIEKEEEF_02121	9.3e-63	psd	4.1.1.65		I	Belongs to the phosphatidylserine decarboxylase family
PIEKEEEF_02122	8.2e-19				K	Helix-turn-helix XRE-family like proteins
PIEKEEEF_02123	4.3e-283	repE			K	Primase C terminal 1 (PriCT-1)
PIEKEEEF_02124	1.6e-126	pyrF	4.1.1.23		F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIEKEEEF_02125	1.1e-118	pyrE	2.4.2.10, 4.1.1.23		F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIEKEEEF_02126	5.3e-20	clcA			P	chloride
PIEKEEEF_02127	2.8e-33	clcA			P	chloride