ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDHCIICM_00001 3.3e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDHCIICM_00002 1.2e-61 ribT K acetyltransferase
HDHCIICM_00003 1.8e-167 xerD D recombinase XerD
HDHCIICM_00004 5.7e-166 cvfB S S1 domain
HDHCIICM_00005 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDHCIICM_00006 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDHCIICM_00008 0.0 dnaE 2.7.7.7 L DNA polymerase
HDHCIICM_00009 2.1e-28 S Protein of unknown function (DUF2929)
HDHCIICM_00010 2.6e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDHCIICM_00011 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDHCIICM_00012 2.8e-46 yrvD S Lipopolysaccharide assembly protein A domain
HDHCIICM_00013 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDHCIICM_00014 2e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDHCIICM_00015 0.0 oatA I Acyltransferase
HDHCIICM_00016 1.5e-239 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDHCIICM_00017 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDHCIICM_00018 2.3e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HDHCIICM_00019 1.6e-95 dedA 3.1.3.1 S SNARE associated Golgi protein
HDHCIICM_00020 2.1e-114 GM NmrA-like family
HDHCIICM_00021 1.1e-245 yagE E amino acid
HDHCIICM_00022 1.3e-79 S Rib/alpha-like repeat
HDHCIICM_00023 7.8e-64 S Domain of unknown function DUF1828
HDHCIICM_00024 7.2e-68
HDHCIICM_00025 5.8e-35
HDHCIICM_00026 4.3e-82 mutT 3.6.1.55 F NUDIX domain
HDHCIICM_00027 4.1e-73
HDHCIICM_00028 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDHCIICM_00029 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDHCIICM_00030 1.8e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDHCIICM_00031 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDHCIICM_00032 2.4e-65
HDHCIICM_00033 1.1e-172 prmA J Ribosomal protein L11 methyltransferase
HDHCIICM_00034 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDHCIICM_00035 8.1e-198 S Bacterial membrane protein, YfhO
HDHCIICM_00036 1.3e-304 S Bacterial membrane protein, YfhO
HDHCIICM_00037 0.0 aha1 P E1-E2 ATPase
HDHCIICM_00038 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
HDHCIICM_00039 2.9e-257 yjjP S Putative threonine/serine exporter
HDHCIICM_00040 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDHCIICM_00041 1.8e-259 frdC 1.3.5.4 C FAD binding domain
HDHCIICM_00042 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDHCIICM_00043 8.2e-67 metI P ABC transporter permease
HDHCIICM_00044 6.3e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDHCIICM_00045 8.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
HDHCIICM_00046 7.1e-58 L nuclease
HDHCIICM_00047 4.5e-144 F DNA/RNA non-specific endonuclease
HDHCIICM_00048 2.7e-41 K Helix-turn-helix domain
HDHCIICM_00049 1e-270 ybiT S ABC transporter, ATP-binding protein
HDHCIICM_00050 2.7e-16 ybiT S ABC transporter, ATP-binding protein
HDHCIICM_00051 1.1e-17 S Sugar efflux transporter for intercellular exchange
HDHCIICM_00052 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDHCIICM_00053 9.4e-101 3.6.1.27 I Acid phosphatase homologues
HDHCIICM_00055 6e-157 lysR5 K LysR substrate binding domain
HDHCIICM_00056 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HDHCIICM_00057 1.5e-250 G Major Facilitator
HDHCIICM_00058 2.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDHCIICM_00059 2.6e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDHCIICM_00060 1e-159 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDHCIICM_00061 2.6e-112 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDHCIICM_00062 3.9e-276 yjeM E Amino Acid
HDHCIICM_00063 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDHCIICM_00064 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDHCIICM_00065 7.9e-123 srtA 3.4.22.70 M sortase family
HDHCIICM_00066 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDHCIICM_00067 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDHCIICM_00068 0.0 dnaK O Heat shock 70 kDa protein
HDHCIICM_00069 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDHCIICM_00070 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDHCIICM_00071 4.4e-120 S GyrI-like small molecule binding domain
HDHCIICM_00072 3.7e-282 lsa S ABC transporter
HDHCIICM_00073 2.9e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDHCIICM_00074 2.2e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDHCIICM_00075 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDHCIICM_00076 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDHCIICM_00077 6e-46 rplGA J ribosomal protein
HDHCIICM_00078 2e-46 ylxR K Protein of unknown function (DUF448)
HDHCIICM_00079 1.1e-217 nusA K Participates in both transcription termination and antitermination
HDHCIICM_00080 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
HDHCIICM_00081 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDHCIICM_00082 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDHCIICM_00083 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDHCIICM_00084 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HDHCIICM_00085 7.9e-134 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDHCIICM_00086 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDHCIICM_00087 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDHCIICM_00088 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDHCIICM_00089 1.1e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HDHCIICM_00090 9.5e-181 yabB 2.1.1.223 L Methyltransferase small domain
HDHCIICM_00091 1.9e-115 plsC 2.3.1.51 I Acyltransferase
HDHCIICM_00092 3.6e-224 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDHCIICM_00093 1.5e-298 mdlB V ABC transporter
HDHCIICM_00094 0.0 mdlA V ABC transporter
HDHCIICM_00095 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
HDHCIICM_00096 1.2e-33 ynzC S UPF0291 protein
HDHCIICM_00097 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDHCIICM_00098 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDHCIICM_00099 1.4e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HDHCIICM_00100 4.6e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDHCIICM_00101 2.9e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDHCIICM_00102 4.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDHCIICM_00103 8.1e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDHCIICM_00104 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDHCIICM_00105 1.2e-226 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDHCIICM_00106 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDHCIICM_00107 1.2e-285 pipD E Dipeptidase
HDHCIICM_00108 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDHCIICM_00109 0.0 smc D Required for chromosome condensation and partitioning
HDHCIICM_00110 6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDHCIICM_00111 0.0 oppA E ABC transporter substrate-binding protein
HDHCIICM_00112 0.0 oppA E ABC transporter substrate-binding protein
HDHCIICM_00113 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
HDHCIICM_00114 7.5e-180 oppB P ABC transporter permease
HDHCIICM_00115 4.4e-180 oppF P Belongs to the ABC transporter superfamily
HDHCIICM_00116 1.1e-192 oppD P Belongs to the ABC transporter superfamily
HDHCIICM_00117 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDHCIICM_00118 1.4e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDHCIICM_00119 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDHCIICM_00120 3.6e-307 yloV S DAK2 domain fusion protein YloV
HDHCIICM_00121 1.4e-57 asp S Asp23 family, cell envelope-related function
HDHCIICM_00122 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDHCIICM_00123 2.5e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDHCIICM_00124 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDHCIICM_00125 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDHCIICM_00126 0.0 KLT serine threonine protein kinase
HDHCIICM_00127 4.5e-140 stp 3.1.3.16 T phosphatase
HDHCIICM_00128 5.5e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDHCIICM_00129 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDHCIICM_00130 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDHCIICM_00131 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDHCIICM_00132 8.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HDHCIICM_00133 4.6e-48
HDHCIICM_00134 1.8e-258 recN L May be involved in recombinational repair of damaged DNA
HDHCIICM_00135 1.4e-155 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDHCIICM_00136 7.8e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDHCIICM_00137 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDHCIICM_00138 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDHCIICM_00139 2e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDHCIICM_00140 3e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDHCIICM_00141 2.2e-73 yqhY S Asp23 family, cell envelope-related function
HDHCIICM_00142 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDHCIICM_00143 4e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDHCIICM_00144 3.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDHCIICM_00145 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDHCIICM_00146 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HDHCIICM_00147 3.5e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDHCIICM_00148 1.1e-242 S Uncharacterized protein conserved in bacteria (DUF2325)
HDHCIICM_00149 1.2e-12
HDHCIICM_00150 5.8e-18 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDHCIICM_00151 2e-92 S ECF-type riboflavin transporter, S component
HDHCIICM_00152 1.2e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HDHCIICM_00153 4.5e-58
HDHCIICM_00154 1.8e-54 K Acetyltransferase (GNAT) domain
HDHCIICM_00155 4.4e-303 S Predicted membrane protein (DUF2207)
HDHCIICM_00156 1.4e-188 yhjX P Major Facilitator Superfamily
HDHCIICM_00157 2.3e-175 I Carboxylesterase family
HDHCIICM_00158 4e-164 rhaS6 K helix_turn_helix, arabinose operon control protein
HDHCIICM_00159 1.4e-167 2.7.1.2 GK ROK family
HDHCIICM_00160 7.9e-257 pepC 3.4.22.40 E Peptidase C1-like family
HDHCIICM_00161 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
HDHCIICM_00162 0.0 oppA E ABC transporter substrate-binding protein
HDHCIICM_00163 1.2e-76 K MerR HTH family regulatory protein
HDHCIICM_00164 5.2e-265 lmrB EGP Major facilitator Superfamily
HDHCIICM_00165 3.5e-97 S Domain of unknown function (DUF4811)
HDHCIICM_00166 2.5e-126 pnb C nitroreductase
HDHCIICM_00167 7.6e-224 I transferase activity, transferring acyl groups other than amino-acyl groups
HDHCIICM_00168 3e-107 fic D Fic/DOC family
HDHCIICM_00169 2.1e-70
HDHCIICM_00170 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDHCIICM_00172 1.6e-118 S CAAX protease self-immunity
HDHCIICM_00173 3.2e-141 S haloacid dehalogenase-like hydrolase
HDHCIICM_00174 0.0 pepN 3.4.11.2 E aminopeptidase
HDHCIICM_00175 4.7e-83
HDHCIICM_00176 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDHCIICM_00177 9.5e-231 sptS 2.7.13.3 T Histidine kinase
HDHCIICM_00178 2.4e-116 K response regulator
HDHCIICM_00179 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HDHCIICM_00180 1.1e-115 ltrA S Bacterial low temperature requirement A protein (LtrA)
HDHCIICM_00181 2e-65 O OsmC-like protein
HDHCIICM_00182 5.1e-287 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDHCIICM_00183 7e-178 E ABC transporter, ATP-binding protein
HDHCIICM_00184 4.1e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_00185 2.3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDHCIICM_00186 1.9e-164 yihY S Belongs to the UPF0761 family
HDHCIICM_00187 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
HDHCIICM_00188 8.5e-78 fld C Flavodoxin
HDHCIICM_00189 1.4e-87 gtcA S Teichoic acid glycosylation protein
HDHCIICM_00190 7.2e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDHCIICM_00193 3.6e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_00194 4.9e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDHCIICM_00195 2.6e-137 M Glycosyl hydrolases family 25
HDHCIICM_00196 3.8e-235 potE E amino acid
HDHCIICM_00197 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDHCIICM_00198 2.3e-251 yhdP S Transporter associated domain
HDHCIICM_00199 2.5e-132
HDHCIICM_00200 1.7e-119 C nitroreductase
HDHCIICM_00201 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDHCIICM_00202 3.4e-138 glcR K DeoR C terminal sensor domain
HDHCIICM_00203 5.9e-52 S Enterocin A Immunity
HDHCIICM_00204 4e-133 gntR K UbiC transcription regulator-associated domain protein
HDHCIICM_00205 2.2e-173 rihB 3.2.2.1 F Nucleoside
HDHCIICM_00206 2.2e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDHCIICM_00207 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDHCIICM_00209 5.8e-85 dps P Belongs to the Dps family
HDHCIICM_00210 2.9e-282 S C4-dicarboxylate anaerobic carrier
HDHCIICM_00211 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HDHCIICM_00212 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDHCIICM_00213 5.3e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDHCIICM_00214 1.1e-156 pstA P Phosphate transport system permease protein PstA
HDHCIICM_00215 8e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HDHCIICM_00216 1e-159 pstS P Phosphate
HDHCIICM_00217 2.4e-95 K Acetyltransferase (GNAT) domain
HDHCIICM_00218 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDHCIICM_00219 2.9e-255 glnPH2 P ABC transporter permease
HDHCIICM_00220 2.6e-160 rssA S Phospholipase, patatin family
HDHCIICM_00221 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HDHCIICM_00226 5.3e-33 S Enterocin A Immunity
HDHCIICM_00227 7.9e-63 M Transport protein ComB
HDHCIICM_00228 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDHCIICM_00229 2e-122 K LytTr DNA-binding domain
HDHCIICM_00230 2.3e-118 2.7.13.3 T GHKL domain
HDHCIICM_00232 1.1e-203 EGP Major facilitator superfamily
HDHCIICM_00233 1.7e-111 udk 2.7.1.48 F Cytidine monophosphokinase
HDHCIICM_00237 1.4e-67 S Putative adhesin
HDHCIICM_00238 7.4e-73 treB 2.7.1.211 G phosphotransferase system
HDHCIICM_00239 2.3e-254 treB 2.7.1.211 G phosphotransferase system
HDHCIICM_00240 9.2e-130 treR K UTRA
HDHCIICM_00241 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HDHCIICM_00242 5.6e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_00243 3.4e-107 glnP P ABC transporter permease
HDHCIICM_00244 3.2e-110 gluC P ABC transporter permease
HDHCIICM_00245 2.2e-148 glnH ET ABC transporter
HDHCIICM_00246 4e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDHCIICM_00247 2.7e-146 glnH ET ABC transporter
HDHCIICM_00248 1.6e-277 V ABC transporter transmembrane region
HDHCIICM_00249 1.7e-14 V ABC transporter transmembrane region
HDHCIICM_00250 7.4e-303 XK27_09600 V ABC transporter, ATP-binding protein
HDHCIICM_00251 1.9e-74 K Transcriptional regulator, MarR family
HDHCIICM_00252 2.1e-149 S Alpha beta hydrolase
HDHCIICM_00253 5.6e-78 naiP EGP Major facilitator Superfamily
HDHCIICM_00254 1e-102 naiP EGP Major facilitator Superfamily
HDHCIICM_00255 1.5e-264 dtpT U amino acid peptide transporter
HDHCIICM_00256 8.9e-25 3.2.1.177 GH31 G Glycosyl hydrolases family 31
HDHCIICM_00257 1.2e-43 3.2.1.177 GH31 G Glycosyl hydrolases family 31
HDHCIICM_00258 2.5e-266 3.2.1.177 GH31 G Glycosyl hydrolases family 31
HDHCIICM_00259 6.9e-181 lacI3 K helix_turn _helix lactose operon repressor
HDHCIICM_00260 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HDHCIICM_00261 6.8e-72 2.7.1.191 G PTS system fructose IIA component
HDHCIICM_00262 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
HDHCIICM_00263 2.3e-102 G PTS system sorbose-specific iic component
HDHCIICM_00264 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
HDHCIICM_00266 2.1e-207 pepA E M42 glutamyl aminopeptidase
HDHCIICM_00268 4.3e-77
HDHCIICM_00269 1.3e-70 K helix_turn_helix multiple antibiotic resistance protein
HDHCIICM_00270 2.8e-31
HDHCIICM_00271 3.3e-217 mdtG EGP Major facilitator Superfamily
HDHCIICM_00272 2.4e-110 3.6.1.27 I Acid phosphatase homologues
HDHCIICM_00273 5.1e-52 dhaM 2.7.1.121 S PTS system fructose IIA component
HDHCIICM_00274 1.2e-90 dhaL 2.7.1.121 S Dak2
HDHCIICM_00275 4.7e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDHCIICM_00276 7e-159 glsA 3.5.1.2 E Belongs to the glutaminase family
HDHCIICM_00277 2.7e-258 P Sodium:sulfate symporter transmembrane region
HDHCIICM_00278 0.0 1.3.5.4 C FMN_bind
HDHCIICM_00279 3.4e-163 K LysR family
HDHCIICM_00280 6e-194 S PFAM Archaeal ATPase
HDHCIICM_00281 5.9e-290 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_00282 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HDHCIICM_00283 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HDHCIICM_00284 1.7e-148 lacT K CAT RNA binding domain
HDHCIICM_00285 1.3e-38
HDHCIICM_00286 3.5e-266 gatC G PTS system sugar-specific permease component
HDHCIICM_00287 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HDHCIICM_00288 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDHCIICM_00289 4.7e-128 S Domain of unknown function (DUF4867)
HDHCIICM_00290 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HDHCIICM_00291 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HDHCIICM_00292 1.3e-137 lacR K DeoR C terminal sensor domain
HDHCIICM_00293 5.6e-242 pyrP F Permease
HDHCIICM_00294 8.1e-170 S PFAM Archaeal ATPase
HDHCIICM_00295 1.7e-132 K Transcriptional regulator
HDHCIICM_00296 4.5e-146 S hydrolase
HDHCIICM_00297 3.2e-103 yagU S Protein of unknown function (DUF1440)
HDHCIICM_00298 1.1e-141 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDHCIICM_00299 1.5e-76 2.3.1.128 K acetyltransferase
HDHCIICM_00300 0.0 4.2.1.53 S Myosin-crossreactive antigen
HDHCIICM_00301 3.4e-70 yxdD K Bacterial regulatory proteins, tetR family
HDHCIICM_00302 7.1e-259 emrY EGP Major facilitator Superfamily
HDHCIICM_00303 1.3e-252 emrY EGP Major facilitator Superfamily
HDHCIICM_00304 5.2e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDHCIICM_00305 2.4e-136 S CAAX amino terminal protease
HDHCIICM_00306 1.5e-164 mleP3 S Membrane transport protein
HDHCIICM_00307 2.8e-105 tag 3.2.2.20 L glycosylase
HDHCIICM_00308 9.8e-191 S Bacteriocin helveticin-J
HDHCIICM_00309 2.9e-239 bglH 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HDHCIICM_00310 1.1e-230 G phosphotransferase system
HDHCIICM_00311 1.3e-41 ybbH_2 K Helix-turn-helix domain, rpiR family
HDHCIICM_00312 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
HDHCIICM_00313 6.6e-108 ylbE GM NAD(P)H-binding
HDHCIICM_00314 2.7e-128 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HDHCIICM_00315 5.4e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDHCIICM_00317 5.2e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HDHCIICM_00318 1.8e-52 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HDHCIICM_00319 2.5e-47
HDHCIICM_00320 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HDHCIICM_00321 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDHCIICM_00322 1.4e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDHCIICM_00323 4e-68 M ErfK YbiS YcfS YnhG
HDHCIICM_00324 1e-35 M ErfK YbiS YcfS YnhG
HDHCIICM_00325 2.1e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDHCIICM_00326 1.4e-117
HDHCIICM_00327 1.1e-214 I Protein of unknown function (DUF2974)
HDHCIICM_00328 2.1e-302 ytgP S Polysaccharide biosynthesis protein
HDHCIICM_00329 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDHCIICM_00330 8e-117 3.6.1.27 I Acid phosphatase homologues
HDHCIICM_00331 8e-258 qacA EGP Major facilitator Superfamily
HDHCIICM_00332 9.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDHCIICM_00336 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HDHCIICM_00337 3e-76 M Protein of unknown function (DUF3737)
HDHCIICM_00338 2.7e-90 patB 4.4.1.8 E Aminotransferase, class I
HDHCIICM_00339 1.5e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDHCIICM_00340 9.2e-68 S SdpI/YhfL protein family
HDHCIICM_00341 1.7e-128 K Transcriptional regulatory protein, C terminal
HDHCIICM_00342 1.9e-267 T PhoQ Sensor
HDHCIICM_00343 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDHCIICM_00344 1.2e-106 vanZ V VanZ like family
HDHCIICM_00345 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
HDHCIICM_00346 5e-209 EGP Major facilitator Superfamily
HDHCIICM_00347 8.5e-70
HDHCIICM_00350 1.2e-188 ampC V Beta-lactamase
HDHCIICM_00351 1.1e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HDHCIICM_00352 5.5e-112 tdk 2.7.1.21 F thymidine kinase
HDHCIICM_00353 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDHCIICM_00354 2.1e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDHCIICM_00355 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDHCIICM_00356 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDHCIICM_00357 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HDHCIICM_00358 1.2e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDHCIICM_00359 2.6e-43 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDHCIICM_00360 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDHCIICM_00361 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDHCIICM_00362 2.7e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDHCIICM_00363 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDHCIICM_00364 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDHCIICM_00365 2e-30 ywzB S Protein of unknown function (DUF1146)
HDHCIICM_00366 2.2e-179 mbl D Cell shape determining protein MreB Mrl
HDHCIICM_00367 2.5e-15 S DNA-directed RNA polymerase subunit beta
HDHCIICM_00368 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDHCIICM_00369 1.3e-34 S Protein of unknown function (DUF2969)
HDHCIICM_00370 4.7e-224 rodA D Belongs to the SEDS family
HDHCIICM_00371 5.2e-81 usp6 T universal stress protein
HDHCIICM_00373 1.8e-237 rarA L recombination factor protein RarA
HDHCIICM_00374 1.5e-80 yueI S Protein of unknown function (DUF1694)
HDHCIICM_00375 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDHCIICM_00377 9.3e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDHCIICM_00378 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HDHCIICM_00379 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDHCIICM_00380 6.4e-120 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDHCIICM_00381 1.4e-206 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HDHCIICM_00382 0.0 3.6.3.8 P P-type ATPase
HDHCIICM_00383 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDHCIICM_00384 4.6e-85 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDHCIICM_00385 8.2e-117 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDHCIICM_00386 7.8e-123 S Haloacid dehalogenase-like hydrolase
HDHCIICM_00387 5.2e-110 radC L DNA repair protein
HDHCIICM_00388 8.4e-166 mreB D cell shape determining protein MreB
HDHCIICM_00389 1e-143 mreC M Involved in formation and maintenance of cell shape
HDHCIICM_00390 1.2e-91 mreD
HDHCIICM_00391 3.6e-13 S Protein of unknown function (DUF4044)
HDHCIICM_00392 6.1e-52 S Protein of unknown function (DUF3397)
HDHCIICM_00393 4.1e-77 mraZ K Belongs to the MraZ family
HDHCIICM_00394 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDHCIICM_00395 6.3e-55 ftsL D Cell division protein FtsL
HDHCIICM_00396 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDHCIICM_00397 5.9e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDHCIICM_00398 4.7e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDHCIICM_00399 8e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDHCIICM_00400 1.8e-153 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDHCIICM_00401 4.6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDHCIICM_00402 1.2e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDHCIICM_00403 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDHCIICM_00404 2e-27 yggT S YGGT family
HDHCIICM_00405 2.6e-146 ylmH S S4 domain protein
HDHCIICM_00406 1.8e-118 gpsB D DivIVA domain protein
HDHCIICM_00407 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDHCIICM_00408 2e-32 cspA K 'Cold-shock' DNA-binding domain
HDHCIICM_00409 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HDHCIICM_00411 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDHCIICM_00412 3.6e-213 iscS 2.8.1.7 E Aminotransferase class V
HDHCIICM_00413 1.6e-57 XK27_04120 S Putative amino acid metabolism
HDHCIICM_00414 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDHCIICM_00415 6.4e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HDHCIICM_00416 2.2e-114 S Repeat protein
HDHCIICM_00417 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDHCIICM_00418 1.7e-168 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDHCIICM_00419 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDHCIICM_00420 3e-34 ykzG S Belongs to the UPF0356 family
HDHCIICM_00421 5.8e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDHCIICM_00422 0.0 typA T GTP-binding protein TypA
HDHCIICM_00423 5.9e-211 ftsW D Belongs to the SEDS family
HDHCIICM_00424 6.1e-52 ylbG S UPF0298 protein
HDHCIICM_00425 7.2e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HDHCIICM_00426 5.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDHCIICM_00427 8.7e-179 ylbL T Belongs to the peptidase S16 family
HDHCIICM_00428 3.6e-75 comEA L Competence protein ComEA
HDHCIICM_00429 7.2e-51 comEC S Competence protein ComEC
HDHCIICM_00430 0.0 comEC S Competence protein ComEC
HDHCIICM_00431 1e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
HDHCIICM_00432 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HDHCIICM_00433 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDHCIICM_00434 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDHCIICM_00435 3.8e-159
HDHCIICM_00436 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDHCIICM_00437 2.1e-204 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDHCIICM_00438 3.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDHCIICM_00439 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
HDHCIICM_00440 8.2e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDHCIICM_00441 1.2e-80
HDHCIICM_00442 4.3e-68 S Domain of unknown function (DUF4767)
HDHCIICM_00443 1.2e-220
HDHCIICM_00444 7.1e-121 frnE Q DSBA-like thioredoxin domain
HDHCIICM_00445 1.7e-159
HDHCIICM_00446 5e-76 K DNA-templated transcription, initiation
HDHCIICM_00447 4.9e-158 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDHCIICM_00448 2e-136 epsB M biosynthesis protein
HDHCIICM_00449 1.2e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HDHCIICM_00450 2e-143 ywqE 3.1.3.48 GM PHP domain protein
HDHCIICM_00451 2.7e-120 rfbP M Bacterial sugar transferase
HDHCIICM_00452 6.8e-83 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HDHCIICM_00453 2.1e-85 pssE S Glycosyltransferase family 28 C-terminal domain
HDHCIICM_00454 1.5e-124 M Glycosyltransferase sugar-binding region containing DXD motif
HDHCIICM_00455 1.4e-183 2.4.1.308 GT11 S N-acetyllactosaminide 3-alpha-galactosyltransferase activity
HDHCIICM_00456 1.3e-159 GT2 S Glycosyl transferase family 2
HDHCIICM_00457 3.3e-197 cps1B GT2,GT4 M Glycosyl transferases group 1
HDHCIICM_00458 4.7e-199 wbbI M transferase activity, transferring glycosyl groups
HDHCIICM_00459 8.8e-195 M Glycosyl transferase family 2
HDHCIICM_00460 1.8e-212
HDHCIICM_00461 1.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
HDHCIICM_00462 6.2e-263 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HDHCIICM_00463 6.2e-118 S Acyltransferase family
HDHCIICM_00464 4.3e-151 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDHCIICM_00465 1.2e-14
HDHCIICM_00466 3.1e-88 prrC S Protein conserved in bacteria
HDHCIICM_00467 8.6e-104 L Reverse transcriptase (RNA-dependent DNA polymerase)
HDHCIICM_00469 2.3e-202 K Psort location Cytoplasmic, score
HDHCIICM_00470 1.2e-80 K Psort location Cytoplasmic, score
HDHCIICM_00471 6.1e-95 K Psort location Cytoplasmic, score
HDHCIICM_00472 2.4e-284 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HDHCIICM_00473 1.7e-11 yttA 2.7.13.3 S Pfam Transposase IS66
HDHCIICM_00474 1e-142 V Abi-like protein
HDHCIICM_00475 6.1e-224 KQ helix_turn_helix, mercury resistance
HDHCIICM_00476 1.8e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDHCIICM_00477 3.9e-167 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDHCIICM_00478 8.8e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDHCIICM_00479 1.3e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDHCIICM_00480 9.7e-37 cpsJ S glycosyl transferase family 2
HDHCIICM_00481 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDHCIICM_00482 7.2e-148 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDHCIICM_00483 4.4e-41 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDHCIICM_00484 6.1e-80 S CRISPR-associated protein (Cas_Csn2)
HDHCIICM_00485 1.7e-18 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDHCIICM_00486 8.1e-08 S HIRAN
HDHCIICM_00487 1.1e-46 S HIRAN
HDHCIICM_00488 3.1e-151 htpX O Peptidase family M48
HDHCIICM_00489 1.1e-271 cas3 L CRISPR-associated helicase cas3
HDHCIICM_00490 3.2e-149 casA L the current gene model (or a revised gene model) may contain a frame shift
HDHCIICM_00491 3.3e-32 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HDHCIICM_00492 1.3e-114 casC L CT1975-like protein
HDHCIICM_00493 2e-65 casD S CRISPR-associated protein (Cas_Cas5)
HDHCIICM_00494 7.4e-107 casE S CRISPR_assoc
HDHCIICM_00495 5.8e-153 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDHCIICM_00496 1.3e-85 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HDHCIICM_00497 1.1e-29
HDHCIICM_00498 3.4e-222 patA 2.6.1.1 E Aminotransferase
HDHCIICM_00499 1.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDHCIICM_00500 1.7e-142 E GDSL-like Lipase/Acylhydrolase family
HDHCIICM_00501 1.9e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDHCIICM_00502 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDHCIICM_00503 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDHCIICM_00504 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDHCIICM_00505 2.3e-38 yqeY S YqeY-like protein
HDHCIICM_00506 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
HDHCIICM_00507 1e-90 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDHCIICM_00508 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDHCIICM_00509 4e-136 recO L Involved in DNA repair and RecF pathway recombination
HDHCIICM_00510 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDHCIICM_00511 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDHCIICM_00512 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDHCIICM_00513 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDHCIICM_00514 9.9e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDHCIICM_00515 1.2e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDHCIICM_00516 3.6e-243 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDHCIICM_00517 2.8e-58 yvoA_1 K Transcriptional regulator, GntR family
HDHCIICM_00518 2.1e-123 skfE V ATPases associated with a variety of cellular activities
HDHCIICM_00519 3e-129
HDHCIICM_00520 7.9e-109
HDHCIICM_00521 8.1e-22
HDHCIICM_00522 1.4e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDHCIICM_00523 3.7e-131
HDHCIICM_00524 3.4e-164
HDHCIICM_00525 3.2e-232 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HDHCIICM_00526 9.4e-50 ybjQ S Belongs to the UPF0145 family
HDHCIICM_00527 9.2e-160 XK27_05540 S DUF218 domain
HDHCIICM_00528 9e-150 yxeH S hydrolase
HDHCIICM_00529 3.4e-302 I Protein of unknown function (DUF2974)
HDHCIICM_00530 2.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDHCIICM_00531 3.8e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDHCIICM_00532 2.2e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDHCIICM_00533 7.9e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDHCIICM_00534 5.5e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDHCIICM_00535 2e-241 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDHCIICM_00536 1.8e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDHCIICM_00537 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDHCIICM_00538 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDHCIICM_00539 3.2e-103 pncA Q Isochorismatase family
HDHCIICM_00540 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HDHCIICM_00541 1e-122 alkD L DNA alkylation repair enzyme
HDHCIICM_00542 2.3e-125 XK27_06785 V ABC transporter, ATP-binding protein
HDHCIICM_00543 0.0 XK27_06780 V ABC transporter permease
HDHCIICM_00544 2.2e-91 S Protein of unknown function (DUF554)
HDHCIICM_00545 1.2e-51 K LysR substrate binding domain
HDHCIICM_00546 6e-245 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDHCIICM_00547 1.9e-66 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDHCIICM_00548 1.3e-22
HDHCIICM_00549 0.0 pepO 3.4.24.71 O Peptidase family M13
HDHCIICM_00550 1.7e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDHCIICM_00551 3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDHCIICM_00552 6.8e-273 thrC 4.2.3.1 E Threonine synthase
HDHCIICM_00553 6.8e-226 hom1 1.1.1.3 E homoserine dehydrogenase
HDHCIICM_00554 1.1e-153 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDHCIICM_00555 1.1e-167 lysR7 K LysR substrate binding domain
HDHCIICM_00556 0.0 1.3.5.4 C FMN_bind
HDHCIICM_00557 3.2e-118 drgA C nitroreductase
HDHCIICM_00558 4.5e-26
HDHCIICM_00559 8.4e-50
HDHCIICM_00560 2.7e-37 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDHCIICM_00561 7e-65 K CAT RNA binding domain
HDHCIICM_00562 5.9e-165 G phosphotransferase system, EIIB
HDHCIICM_00563 5e-86 G YdjC-like protein
HDHCIICM_00564 1.5e-72 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HDHCIICM_00565 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDHCIICM_00566 3.1e-53
HDHCIICM_00567 8.5e-13
HDHCIICM_00568 4.2e-103 speG J Acetyltransferase (GNAT) domain
HDHCIICM_00569 7.4e-66 K sequence-specific DNA binding
HDHCIICM_00570 3.4e-40 S SnoaL-like domain
HDHCIICM_00571 8.6e-137 S Protein of unknown function (DUF975)
HDHCIICM_00572 3.6e-128 qmcA O prohibitin homologues
HDHCIICM_00573 4.2e-147 ropB K Helix-turn-helix domain
HDHCIICM_00574 6.7e-290 V ABC-type multidrug transport system, ATPase and permease components
HDHCIICM_00575 3.7e-79 C nitroreductase
HDHCIICM_00576 7.5e-278 V ABC transporter transmembrane region
HDHCIICM_00577 6.9e-48
HDHCIICM_00578 1.3e-73 K Acetyltransferase (GNAT) domain
HDHCIICM_00579 2.6e-46 S MazG-like family
HDHCIICM_00580 1.7e-45
HDHCIICM_00581 3.1e-22 S Protein of unknown function (DUF3923)
HDHCIICM_00582 2.7e-51 S endonuclease activity
HDHCIICM_00583 2.5e-43
HDHCIICM_00584 1.5e-92 rimL J Acetyltransferase (GNAT) domain
HDHCIICM_00585 2.6e-80 2.3.1.57 K Acetyltransferase (GNAT) family
HDHCIICM_00587 3e-44 XK27_07525 3.6.1.55 F NUDIX domain
HDHCIICM_00588 1.6e-49 XK27_07525 3.6.1.55 F NUDIX domain
HDHCIICM_00589 2.2e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDHCIICM_00590 4.5e-160 yvgN C Aldo keto reductase
HDHCIICM_00592 4.8e-80 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_00593 1.2e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_00594 2.1e-53 licT K CAT RNA binding domain
HDHCIICM_00595 8.7e-196 G Psort location CytoplasmicMembrane, score 10.00
HDHCIICM_00596 1.1e-179 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_00597 7.4e-76 K acetyltransferase
HDHCIICM_00598 1.4e-117 S Putative ABC-transporter type IV
HDHCIICM_00599 4.8e-108 M LysM domain protein
HDHCIICM_00600 3.8e-96 M LysM domain protein
HDHCIICM_00602 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
HDHCIICM_00603 1e-187 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HDHCIICM_00604 2.1e-56 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDHCIICM_00605 1.8e-145 K SIS domain
HDHCIICM_00606 4.9e-165 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HDHCIICM_00609 1.4e-52 P Rhodanese Homology Domain
HDHCIICM_00610 1.6e-189
HDHCIICM_00611 9.5e-124 gntR1 K UTRA
HDHCIICM_00612 4.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HDHCIICM_00613 3.4e-132 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDHCIICM_00614 2.7e-202 csaB M Glycosyl transferases group 1
HDHCIICM_00615 0.0 tuaG GT2 M Glycosyltransferase like family 2
HDHCIICM_00616 8.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDHCIICM_00617 2.6e-144 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDHCIICM_00618 0.0 pacL 3.6.3.8 P P-type ATPase
HDHCIICM_00619 4.4e-286 V ABC transporter transmembrane region
HDHCIICM_00620 1.8e-142
HDHCIICM_00621 4.4e-227 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDHCIICM_00622 2.5e-256 epsU S Polysaccharide biosynthesis protein
HDHCIICM_00623 6.6e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HDHCIICM_00624 3.3e-85 ydcK S Belongs to the SprT family
HDHCIICM_00626 2.6e-101 S ECF transporter, substrate-specific component
HDHCIICM_00627 2.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HDHCIICM_00628 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDHCIICM_00629 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDHCIICM_00630 5e-207 camS S sex pheromone
HDHCIICM_00631 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDHCIICM_00632 5.8e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDHCIICM_00633 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDHCIICM_00634 7.3e-169 yegS 2.7.1.107 G Lipid kinase
HDHCIICM_00636 2.8e-151 S hydrolase
HDHCIICM_00637 8.9e-98 L hmm pf00665
HDHCIICM_00638 8.9e-35 L hmm pf00665
HDHCIICM_00639 1.4e-127 L Helix-turn-helix domain
HDHCIICM_00640 5.6e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HDHCIICM_00641 8.1e-88 S ECF transporter, substrate-specific component
HDHCIICM_00642 7.2e-65 S Domain of unknown function (DUF4430)
HDHCIICM_00643 6.5e-153 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HDHCIICM_00644 9.2e-270 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HDHCIICM_00645 7.2e-119 ybhL S Belongs to the BI1 family
HDHCIICM_00646 7e-142 cbiQ P cobalt transport
HDHCIICM_00647 0.0 ykoD P ABC transporter, ATP-binding protein
HDHCIICM_00648 4.3e-95 S UPF0397 protein
HDHCIICM_00649 2.8e-162 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HDHCIICM_00650 1.6e-236 nhaC C Na H antiporter NhaC
HDHCIICM_00651 8.3e-128 mutF V ABC transporter, ATP-binding protein
HDHCIICM_00652 2.8e-120 spaE S ABC-2 family transporter protein
HDHCIICM_00653 7.1e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDHCIICM_00654 1.2e-135 2.1.1.72 V type I restriction-modification system
HDHCIICM_00655 3.1e-122 2.1.1.72 V type I restriction-modification system
HDHCIICM_00656 1.4e-53 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HDHCIICM_00657 4.3e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
HDHCIICM_00658 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDHCIICM_00659 1.4e-192 V Beta-lactamase
HDHCIICM_00662 7.9e-91 3.6.1.55 L NUDIX domain
HDHCIICM_00663 2.1e-64
HDHCIICM_00664 2.7e-257 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDHCIICM_00666 1.2e-157 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDHCIICM_00667 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDHCIICM_00668 3.3e-56 yheA S Belongs to the UPF0342 family
HDHCIICM_00669 5.7e-225 yhaO L Ser Thr phosphatase family protein
HDHCIICM_00670 0.0 L AAA domain
HDHCIICM_00671 4.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDHCIICM_00672 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDHCIICM_00673 3.4e-21 S YtxH-like protein
HDHCIICM_00674 2e-64
HDHCIICM_00675 3.2e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
HDHCIICM_00676 2.2e-131 ecsA V ABC transporter, ATP-binding protein
HDHCIICM_00677 3e-226 ecsB U ABC transporter
HDHCIICM_00678 5.7e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDHCIICM_00679 1.5e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_00680 6.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDHCIICM_00681 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDHCIICM_00682 5.3e-78 ymfC K UTRA
HDHCIICM_00683 1.7e-23 ymfC K UTRA
HDHCIICM_00684 3.9e-256 3.5.1.18 E Peptidase family M20/M25/M40
HDHCIICM_00685 5.9e-177 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HDHCIICM_00686 2.5e-92 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HDHCIICM_00687 2.4e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_00688 2.5e-115 cutC P Participates in the control of copper homeostasis
HDHCIICM_00689 2.4e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDHCIICM_00690 1e-96 K UTRA
HDHCIICM_00691 5e-60 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDHCIICM_00692 1.2e-55 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDHCIICM_00693 9e-189 G Bacterial extracellular solute-binding protein
HDHCIICM_00694 2.9e-114 baeR K helix_turn_helix, Lux Regulon
HDHCIICM_00695 5.7e-199 baeS F Sensor histidine kinase
HDHCIICM_00696 2e-148 rbsB G Periplasmic binding protein domain
HDHCIICM_00697 6.7e-67 levA G PTS system fructose IIA component
HDHCIICM_00698 1.1e-94 2.7.1.191 G PTS system sorbose subfamily IIB component
HDHCIICM_00699 3e-140 M PTS system sorbose-specific iic component
HDHCIICM_00700 4.9e-151 levD G PTS system mannose/fructose/sorbose family IID component
HDHCIICM_00701 2e-46
HDHCIICM_00702 1.2e-65 rmaI K Transcriptional regulator
HDHCIICM_00703 5.3e-137 EGP Major facilitator Superfamily
HDHCIICM_00704 7.8e-35 EGP Major facilitator Superfamily
HDHCIICM_00705 1.5e-227 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HDHCIICM_00706 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDHCIICM_00707 1.7e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDHCIICM_00708 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDHCIICM_00709 5.9e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDHCIICM_00710 2.1e-244 dnaB L Replication initiation and membrane attachment
HDHCIICM_00711 2.8e-160 dnaI L Primosomal protein DnaI
HDHCIICM_00712 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDHCIICM_00713 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDHCIICM_00714 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDHCIICM_00715 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDHCIICM_00716 1.9e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDHCIICM_00717 2.5e-89 yqeG S HAD phosphatase, family IIIA
HDHCIICM_00718 2.6e-208 yqeH S Ribosome biogenesis GTPase YqeH
HDHCIICM_00719 5.7e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDHCIICM_00720 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HDHCIICM_00721 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDHCIICM_00722 2.1e-216 ylbM S Belongs to the UPF0348 family
HDHCIICM_00723 2.9e-96 yceD S Uncharacterized ACR, COG1399
HDHCIICM_00724 1.1e-130 K response regulator
HDHCIICM_00725 1.9e-281 arlS 2.7.13.3 T Histidine kinase
HDHCIICM_00726 3.2e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDHCIICM_00727 1.9e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDHCIICM_00728 6.9e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDHCIICM_00729 7.3e-64 yodB K Transcriptional regulator, HxlR family
HDHCIICM_00730 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDHCIICM_00731 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDHCIICM_00732 1.3e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDHCIICM_00733 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDHCIICM_00734 0.0 S membrane
HDHCIICM_00735 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HDHCIICM_00736 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDHCIICM_00737 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDHCIICM_00738 2.4e-119 gluP 3.4.21.105 S Rhomboid family
HDHCIICM_00739 1e-34 yqgQ S Bacterial protein of unknown function (DUF910)
HDHCIICM_00740 1.5e-57 yqhL P Rhodanese-like protein
HDHCIICM_00741 1.1e-18 S Protein of unknown function (DUF3042)
HDHCIICM_00742 1.6e-166 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDHCIICM_00743 1.4e-261 glnA 6.3.1.2 E glutamine synthetase
HDHCIICM_00744 3.7e-205 EGP Major facilitator Superfamily
HDHCIICM_00745 2.1e-151 S haloacid dehalogenase-like hydrolase
HDHCIICM_00746 1.8e-07
HDHCIICM_00747 1.8e-178 D Alpha beta
HDHCIICM_00748 1.1e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HDHCIICM_00749 7.3e-220 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDHCIICM_00750 8.4e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HDHCIICM_00751 1.8e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDHCIICM_00752 1.8e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDHCIICM_00753 5.4e-112 ygaC J Belongs to the UPF0374 family
HDHCIICM_00754 4.9e-90
HDHCIICM_00755 3e-78
HDHCIICM_00756 6.2e-157 hlyX S Transporter associated domain
HDHCIICM_00757 8.7e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDHCIICM_00758 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
HDHCIICM_00759 0.0 clpE O Belongs to the ClpA ClpB family
HDHCIICM_00760 6.9e-26
HDHCIICM_00761 4.2e-40 ptsH G phosphocarrier protein HPR
HDHCIICM_00762 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDHCIICM_00763 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDHCIICM_00764 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDHCIICM_00765 2.5e-161 coiA 3.6.4.12 S Competence protein
HDHCIICM_00766 1e-105 yjbH Q Thioredoxin
HDHCIICM_00767 7.4e-112 yjbK S CYTH
HDHCIICM_00768 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HDHCIICM_00769 4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDHCIICM_00770 1.3e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDHCIICM_00771 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HDHCIICM_00772 3.7e-232 N Uncharacterized conserved protein (DUF2075)
HDHCIICM_00773 9.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HDHCIICM_00774 8.4e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDHCIICM_00775 1e-210 yubA S AI-2E family transporter
HDHCIICM_00776 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDHCIICM_00777 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
HDHCIICM_00778 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDHCIICM_00779 2.2e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HDHCIICM_00780 8.3e-232 S Peptidase M16
HDHCIICM_00781 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
HDHCIICM_00782 4.3e-125 ymfM S Helix-turn-helix domain
HDHCIICM_00783 5.1e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDHCIICM_00784 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDHCIICM_00785 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
HDHCIICM_00786 5.9e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
HDHCIICM_00787 2.5e-118 yvyE 3.4.13.9 S YigZ family
HDHCIICM_00788 4.7e-238 comFA L Helicase C-terminal domain protein
HDHCIICM_00789 7.4e-126 comFC S Competence protein
HDHCIICM_00790 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDHCIICM_00791 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDHCIICM_00792 1.4e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDHCIICM_00793 2.5e-35
HDHCIICM_00794 3.3e-175 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDHCIICM_00795 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDHCIICM_00796 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDHCIICM_00797 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDHCIICM_00798 6e-61 yugI 5.3.1.9 J general stress protein
HDHCIICM_00799 1.4e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HDHCIICM_00800 2.7e-117 dedA S SNARE-like domain protein
HDHCIICM_00801 4.2e-104 S Protein of unknown function (DUF1461)
HDHCIICM_00802 1.1e-147 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDHCIICM_00803 4.5e-97 yutD S Protein of unknown function (DUF1027)
HDHCIICM_00804 1.3e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDHCIICM_00805 5.7e-55
HDHCIICM_00806 4e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDHCIICM_00807 1.2e-274 pepV 3.5.1.18 E dipeptidase PepV
HDHCIICM_00808 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HDHCIICM_00809 1.6e-177 ccpA K catabolite control protein A
HDHCIICM_00810 1.5e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDHCIICM_00811 4e-51
HDHCIICM_00813 5e-154 ykuT M mechanosensitive ion channel
HDHCIICM_00814 2.1e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDHCIICM_00815 2.1e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDHCIICM_00816 7.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDHCIICM_00817 2.4e-68 yslB S Protein of unknown function (DUF2507)
HDHCIICM_00818 1.1e-52 trxA O Belongs to the thioredoxin family
HDHCIICM_00819 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDHCIICM_00820 1.6e-91 cvpA S Colicin V production protein
HDHCIICM_00821 1.8e-50 yrzB S Belongs to the UPF0473 family
HDHCIICM_00822 6.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDHCIICM_00823 2.6e-42 yrzL S Belongs to the UPF0297 family
HDHCIICM_00824 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDHCIICM_00825 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDHCIICM_00826 4.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HDHCIICM_00827 2e-208 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDHCIICM_00828 2.4e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDHCIICM_00829 6.1e-28 yajC U Preprotein translocase
HDHCIICM_00830 8.8e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDHCIICM_00831 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDHCIICM_00832 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDHCIICM_00833 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDHCIICM_00834 0.0 nisT V ABC transporter
HDHCIICM_00835 3.6e-126 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_00836 8.3e-51 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_00837 1.4e-304 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_00838 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDHCIICM_00839 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDHCIICM_00841 7.9e-10 K Acetyltransferase (GNAT) domain
HDHCIICM_00842 6.6e-123 liaI S membrane
HDHCIICM_00843 1e-78 XK27_02470 K LytTr DNA-binding domain
HDHCIICM_00844 3.7e-102 yvdD 3.2.2.10 S Belongs to the LOG family
HDHCIICM_00845 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDHCIICM_00846 0.0 uup S ABC transporter, ATP-binding protein
HDHCIICM_00847 7.7e-227 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HDHCIICM_00849 3.2e-72 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HDHCIICM_00850 3.8e-100 L oxidized base lesion DNA N-glycosylase activity
HDHCIICM_00851 1.2e-11 L oxidized base lesion DNA N-glycosylase activity
HDHCIICM_00852 1.1e-45
HDHCIICM_00853 3.2e-242 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDHCIICM_00854 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDHCIICM_00855 4.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDHCIICM_00856 9.6e-239 clcA P chloride
HDHCIICM_00857 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDHCIICM_00858 5.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HDHCIICM_00859 2.4e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HDHCIICM_00860 1.5e-86 folT S ECF transporter, substrate-specific component
HDHCIICM_00861 1.1e-127 fat 3.1.2.21 I Acyl-ACP thioesterase
HDHCIICM_00862 2.8e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDHCIICM_00863 4.9e-57 yabA L Involved in initiation control of chromosome replication
HDHCIICM_00864 2.4e-153 holB 2.7.7.7 L DNA polymerase III
HDHCIICM_00865 6.5e-51 yaaQ S Cyclic-di-AMP receptor
HDHCIICM_00866 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDHCIICM_00867 2.4e-26 S Protein of unknown function (DUF2508)
HDHCIICM_00868 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDHCIICM_00869 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDHCIICM_00870 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDHCIICM_00871 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDHCIICM_00872 1.9e-23
HDHCIICM_00873 9.5e-112 rsmC 2.1.1.172 J Methyltransferase
HDHCIICM_00874 1.6e-32
HDHCIICM_00875 5.9e-147 kcsA P Ion transport protein
HDHCIICM_00876 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDHCIICM_00877 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDHCIICM_00878 6.4e-145 aatB ET ABC transporter substrate-binding protein
HDHCIICM_00879 5.7e-115 glnQ 3.6.3.21 E ABC transporter
HDHCIICM_00880 2.3e-108 glnP P ABC transporter permease
HDHCIICM_00881 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDHCIICM_00882 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDHCIICM_00883 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HDHCIICM_00884 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDHCIICM_00885 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDHCIICM_00886 1.3e-45 S CAAX protease self-immunity
HDHCIICM_00888 1.2e-188 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDHCIICM_00890 9.4e-56 G Major Facilitator Superfamily
HDHCIICM_00891 1.9e-147 G Major Facilitator Superfamily
HDHCIICM_00892 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDHCIICM_00893 3.3e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDHCIICM_00894 1.1e-281 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HDHCIICM_00895 1.7e-34
HDHCIICM_00896 1.2e-97 yvrI K sigma factor activity
HDHCIICM_00897 8.5e-289 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_00898 1.6e-289 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HDHCIICM_00899 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HDHCIICM_00900 2.3e-151 lacT K PRD domain
HDHCIICM_00901 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDHCIICM_00902 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDHCIICM_00903 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDHCIICM_00904 5.3e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDHCIICM_00905 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDHCIICM_00906 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HDHCIICM_00907 4e-256 pepC 3.4.22.40 E Peptidase C1-like family
HDHCIICM_00908 9.8e-185 S AAA domain
HDHCIICM_00909 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDHCIICM_00910 7e-26
HDHCIICM_00911 4.4e-42
HDHCIICM_00912 3.4e-155 czcD P cation diffusion facilitator family transporter
HDHCIICM_00913 2.6e-52 K Transcriptional regulator, ArsR family
HDHCIICM_00914 1.3e-128 pgm3 G Belongs to the phosphoglycerate mutase family
HDHCIICM_00915 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HDHCIICM_00916 1.3e-159 1.6.5.2 GM NmrA-like family
HDHCIICM_00917 1.3e-72
HDHCIICM_00918 2.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HDHCIICM_00919 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDHCIICM_00920 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDHCIICM_00921 2.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHCIICM_00922 1.8e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHCIICM_00923 1.5e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDHCIICM_00924 7.4e-62 rplQ J Ribosomal protein L17
HDHCIICM_00925 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHCIICM_00926 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDHCIICM_00927 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDHCIICM_00928 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDHCIICM_00929 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDHCIICM_00930 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDHCIICM_00931 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDHCIICM_00932 1.3e-70 rplO J Binds to the 23S rRNA
HDHCIICM_00933 1.4e-23 rpmD J Ribosomal protein L30
HDHCIICM_00934 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDHCIICM_00935 7.4e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDHCIICM_00936 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDHCIICM_00937 3.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDHCIICM_00938 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDHCIICM_00939 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDHCIICM_00940 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDHCIICM_00941 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDHCIICM_00942 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDHCIICM_00943 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HDHCIICM_00944 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDHCIICM_00945 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDHCIICM_00946 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDHCIICM_00947 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDHCIICM_00948 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDHCIICM_00949 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDHCIICM_00950 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HDHCIICM_00951 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDHCIICM_00952 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDHCIICM_00953 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDHCIICM_00954 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDHCIICM_00955 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDHCIICM_00956 1.5e-110 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDHCIICM_00957 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHCIICM_00958 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDHCIICM_00959 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDHCIICM_00961 1.6e-08
HDHCIICM_00962 3.9e-295 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDHCIICM_00963 1.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDHCIICM_00964 7.8e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDHCIICM_00965 0.0 S membrane
HDHCIICM_00966 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDHCIICM_00967 2.8e-246 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDHCIICM_00968 9.9e-61 yabR J S1 RNA binding domain
HDHCIICM_00969 2.3e-60 divIC D Septum formation initiator
HDHCIICM_00970 1.8e-34 yabO J S4 domain protein
HDHCIICM_00971 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDHCIICM_00972 8.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDHCIICM_00973 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDHCIICM_00974 1.2e-123 S (CBS) domain
HDHCIICM_00975 4e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDHCIICM_00976 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDHCIICM_00977 2.9e-260 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDHCIICM_00978 8.5e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDHCIICM_00979 8e-41 rpmE2 J Ribosomal protein L31
HDHCIICM_00980 8.4e-285 ybeC E amino acid
HDHCIICM_00981 5.8e-135 XK27_08845 S ABC transporter, ATP-binding protein
HDHCIICM_00982 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HDHCIICM_00983 2.6e-186 ABC-SBP S ABC transporter
HDHCIICM_00984 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDHCIICM_00985 3.5e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDHCIICM_00986 2.7e-279 pipD E Dipeptidase
HDHCIICM_00987 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDHCIICM_00988 0.0 gph G Transporter
HDHCIICM_00989 1.1e-99 msmR K helix_turn_helix, arabinose operon control protein
HDHCIICM_00990 9.6e-77
HDHCIICM_00991 2.4e-66 S Putative adhesin
HDHCIICM_00992 2.2e-219 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDHCIICM_00993 7.1e-40
HDHCIICM_00994 8.6e-186 yfdV S Membrane transport protein
HDHCIICM_00996 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HDHCIICM_00997 5.3e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HDHCIICM_00998 2.6e-94
HDHCIICM_00999 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDHCIICM_01000 4.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDHCIICM_01001 1.9e-58 M Lysin motif
HDHCIICM_01002 3.4e-98 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDHCIICM_01003 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDHCIICM_01004 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HDHCIICM_01005 3.6e-241 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDHCIICM_01006 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDHCIICM_01007 6.1e-230 S Tetratricopeptide repeat protein
HDHCIICM_01009 1.3e-289 N Uncharacterized conserved protein (DUF2075)
HDHCIICM_01010 1.8e-128 K SIR2-like domain
HDHCIICM_01011 3.1e-83 1.3.5.4 C FMN_bind
HDHCIICM_01012 4.5e-233 1.3.5.4 C FMN_bind
HDHCIICM_01013 3.2e-175 S cog cog1373
HDHCIICM_01014 3.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDHCIICM_01015 3.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDHCIICM_01016 1.3e-114 hlyIII S protein, hemolysin III
HDHCIICM_01017 9.4e-150 DegV S Uncharacterised protein, DegV family COG1307
HDHCIICM_01018 9.2e-36 yozE S Belongs to the UPF0346 family
HDHCIICM_01019 3.3e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HDHCIICM_01020 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDHCIICM_01021 9.2e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDHCIICM_01022 1.9e-150 dprA LU DNA protecting protein DprA
HDHCIICM_01023 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDHCIICM_01024 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDHCIICM_01025 1.2e-169 xerC D Phage integrase, N-terminal SAM-like domain
HDHCIICM_01026 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDHCIICM_01027 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDHCIICM_01028 1.3e-178 lacX 5.1.3.3 G Aldose 1-epimerase
HDHCIICM_01029 6.1e-95 K LysR substrate binding domain
HDHCIICM_01030 3.4e-100 S LexA-binding, inner membrane-associated putative hydrolase
HDHCIICM_01032 4.5e-175 MA20_14895 S Conserved hypothetical protein 698
HDHCIICM_01033 3.1e-44 K LysR substrate binding domain
HDHCIICM_01034 2.4e-193 tanA S alpha beta
HDHCIICM_01035 3.8e-146 K Transcriptional regulator
HDHCIICM_01036 1.5e-84 S NADPH-dependent FMN reductase
HDHCIICM_01037 2.4e-30 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDHCIICM_01038 5.7e-35 S Uncharacterized protein conserved in bacteria (DUF2255)
HDHCIICM_01039 3.7e-101 S Alpha beta hydrolase
HDHCIICM_01040 6.6e-223 lsa S ABC transporter
HDHCIICM_01041 1.9e-47
HDHCIICM_01042 1.8e-40
HDHCIICM_01043 1.8e-14 V KxYKxGKxW signal domain protein
HDHCIICM_01044 8.2e-16 rnhA 3.1.26.4 L Ribonuclease HI
HDHCIICM_01045 1.2e-17 K peptidyl-tyrosine sulfation
HDHCIICM_01046 1.1e-51 higA K Helix-turn-helix XRE-family like proteins
HDHCIICM_01047 9.1e-113 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_01048 8.7e-108 ybbL S ABC transporter, ATP-binding protein
HDHCIICM_01049 1.9e-130 ybbM S Uncharacterised protein family (UPF0014)
HDHCIICM_01050 7.4e-97 K Acetyltransferase (GNAT) domain
HDHCIICM_01051 3.9e-301 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDHCIICM_01052 2e-113 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HDHCIICM_01053 1.7e-48 S Protein of unknown function (DUF3021)
HDHCIICM_01054 6.2e-73 K LytTr DNA-binding domain
HDHCIICM_01055 3.1e-74 S Protein of unknown function (DUF1211)
HDHCIICM_01056 5.8e-08 S Protein of unknown function (DUF1211)
HDHCIICM_01057 2e-47 K Transcriptional regulator
HDHCIICM_01059 4.8e-133 S Oxidoreductase, aldo keto reductase family protein
HDHCIICM_01061 5.8e-18 S reductase
HDHCIICM_01062 1.3e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDHCIICM_01063 3.6e-114 3.6.1.55 F NUDIX domain
HDHCIICM_01064 1.9e-61 S Putative adhesin
HDHCIICM_01065 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
HDHCIICM_01066 1.1e-141 sufC O FeS assembly ATPase SufC
HDHCIICM_01067 8.5e-197 sufD O FeS assembly protein SufD
HDHCIICM_01068 6.2e-187 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDHCIICM_01069 1.2e-63 nifU C SUF system FeS assembly protein, NifU family
HDHCIICM_01070 5.1e-270 sufB O assembly protein SufB
HDHCIICM_01071 1.3e-43 yitW S Iron-sulfur cluster assembly protein
HDHCIICM_01072 1.4e-244 mntH P H( )-stimulated, divalent metal cation uptake system
HDHCIICM_01073 5.8e-67 K HxlR family
HDHCIICM_01074 2.7e-19
HDHCIICM_01075 1e-218 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
HDHCIICM_01076 2.9e-12 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDHCIICM_01077 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDHCIICM_01078 6.4e-285 P ABC transporter
HDHCIICM_01079 2.3e-290 V ABC-type multidrug transport system, ATPase and permease components
HDHCIICM_01080 2.2e-72 yphH S Cupin domain
HDHCIICM_01081 5.8e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDHCIICM_01082 1.9e-33 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HDHCIICM_01083 7.4e-15 mta K helix_turn_helix, mercury resistance
HDHCIICM_01084 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HDHCIICM_01085 3e-149 lmrA 3.6.3.44 V ABC transporter
HDHCIICM_01086 6e-154 C Aldo keto reductase
HDHCIICM_01088 9.2e-101 K Transcriptional regulator C-terminal region
HDHCIICM_01089 2.5e-230 E Alpha/beta hydrolase of unknown function (DUF1100)
HDHCIICM_01090 1.4e-116 GM NAD(P)H-binding
HDHCIICM_01091 3.4e-184 mdt(A) EGP Major facilitator Superfamily
HDHCIICM_01092 6.9e-47 K Bacterial regulatory proteins, tetR family
HDHCIICM_01093 5e-246 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDHCIICM_01094 5.2e-132 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HDHCIICM_01095 3.6e-28 G Major facilitator Superfamily
HDHCIICM_01096 4.2e-261 npr 1.11.1.1 C NADH oxidase
HDHCIICM_01097 1.4e-203 lmrB EGP Major facilitator Superfamily
HDHCIICM_01098 4.8e-68 K Transcriptional regulator
HDHCIICM_01099 1.1e-73 ogt 2.1.1.63, 3.2.2.20 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HDHCIICM_01100 7.5e-62 K helix_turn_helix, arabinose operon control protein
HDHCIICM_01101 5.5e-101 S membrane transporter protein
HDHCIICM_01102 4.9e-14 S Uncharacterized protein conserved in bacteria (DUF2263)
HDHCIICM_01103 2e-197 XK27_00915 C Luciferase-like monooxygenase
HDHCIICM_01104 1.9e-07 K Acetyltransferase (GNAT) domain
HDHCIICM_01105 7.4e-83 XK27_09675 K Acetyltransferase (GNAT) domain
HDHCIICM_01106 6.8e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HDHCIICM_01107 3.4e-244 yrvN L AAA C-terminal domain
HDHCIICM_01108 2.5e-33 4.1.1.45 S Amidohydrolase
HDHCIICM_01109 4.5e-106 4.1.1.45 S Amidohydrolase
HDHCIICM_01110 6.9e-114 ybhL S Belongs to the BI1 family
HDHCIICM_01111 1.2e-159 C Aldo/keto reductase family
HDHCIICM_01112 1.4e-164 akr5f 1.1.1.346 S reductase
HDHCIICM_01113 6.3e-122 magIII L Base excision DNA repair protein, HhH-GPD family
HDHCIICM_01114 7.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
HDHCIICM_01115 4.4e-115 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDHCIICM_01116 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDHCIICM_01117 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDHCIICM_01118 1.6e-177 K Transcriptional regulator
HDHCIICM_01119 5.2e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDHCIICM_01120 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDHCIICM_01121 8.5e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDHCIICM_01122 1.9e-124 yoaK S Protein of unknown function (DUF1275)
HDHCIICM_01123 2e-202 xerS L Belongs to the 'phage' integrase family
HDHCIICM_01124 5.4e-101 K Transcriptional regulator
HDHCIICM_01125 3.1e-150
HDHCIICM_01126 4.2e-161 degV S EDD domain protein, DegV family
HDHCIICM_01127 1.1e-63
HDHCIICM_01128 0.0 FbpA K Fibronectin-binding protein
HDHCIICM_01129 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HDHCIICM_01130 6.3e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDHCIICM_01131 1.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDHCIICM_01132 1.2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDHCIICM_01133 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDHCIICM_01134 1.4e-56
HDHCIICM_01135 1.5e-172 degV S DegV family
HDHCIICM_01136 2e-22 cpdA S Calcineurin-like phosphoesterase
HDHCIICM_01137 8.6e-66 cpdA S Calcineurin-like phosphoesterase
HDHCIICM_01138 1.8e-96 cpdA S Calcineurin-like phosphoesterase
HDHCIICM_01139 2e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDHCIICM_01140 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDHCIICM_01141 7.2e-106 ypsA S Belongs to the UPF0398 family
HDHCIICM_01142 5.9e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDHCIICM_01143 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HDHCIICM_01144 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDHCIICM_01145 5.7e-115 dnaD L DnaD domain protein
HDHCIICM_01146 6.4e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDHCIICM_01147 2.4e-81 ypmB S Protein conserved in bacteria
HDHCIICM_01148 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDHCIICM_01149 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDHCIICM_01150 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDHCIICM_01151 9.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HDHCIICM_01152 1.5e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDHCIICM_01153 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HDHCIICM_01154 2.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDHCIICM_01155 3.9e-266 V ABC-type multidrug transport system, ATPase and permease components
HDHCIICM_01156 4.1e-284 V ABC-type multidrug transport system, ATPase and permease components
HDHCIICM_01157 2.4e-159 G Transmembrane secretion effector
HDHCIICM_01158 1.6e-154 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDHCIICM_01159 2.6e-19 rbsU U ribose uptake protein RbsU
HDHCIICM_01160 7.3e-124 rbsU U ribose uptake protein RbsU
HDHCIICM_01161 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDHCIICM_01162 2.7e-79 6.3.3.2 S ASCH
HDHCIICM_01163 5.3e-136 2.4.2.3 F Phosphorylase superfamily
HDHCIICM_01164 6.4e-68 3.6.1.55 F NUDIX domain
HDHCIICM_01165 3.1e-40 yxaM EGP Major facilitator Superfamily
HDHCIICM_01166 2.1e-94 S ABC-type cobalt transport system, permease component
HDHCIICM_01167 3.4e-169 K helix_turn_helix, arabinose operon control protein
HDHCIICM_01168 5e-146 htpX O Belongs to the peptidase M48B family
HDHCIICM_01169 2.2e-91 lemA S LemA family
HDHCIICM_01170 1.4e-182 ybiR P Citrate transporter
HDHCIICM_01171 1.3e-69 S Iron-sulphur cluster biosynthesis
HDHCIICM_01172 1.7e-16
HDHCIICM_01173 4.5e-152
HDHCIICM_01175 2e-244 ydaM M Glycosyl transferase
HDHCIICM_01176 5.1e-212 G Glycosyl hydrolases family 8
HDHCIICM_01177 4.5e-120 yfbR S HD containing hydrolase-like enzyme
HDHCIICM_01178 1.1e-161 L HNH nucleases
HDHCIICM_01179 9.6e-138 glnQ E ABC transporter, ATP-binding protein
HDHCIICM_01180 9.7e-281 glnP P ABC transporter permease
HDHCIICM_01181 4e-105 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDHCIICM_01182 6.3e-63 yeaO S Protein of unknown function, DUF488
HDHCIICM_01183 1.4e-125 terC P Integral membrane protein TerC family
HDHCIICM_01184 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HDHCIICM_01185 6.6e-134 cobB K SIR2 family
HDHCIICM_01186 2e-80
HDHCIICM_01187 6.4e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDHCIICM_01188 5.6e-124 yugP S Putative neutral zinc metallopeptidase
HDHCIICM_01189 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
HDHCIICM_01190 2.3e-144 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDHCIICM_01191 8.4e-163 ypuA S Protein of unknown function (DUF1002)
HDHCIICM_01192 6.5e-148 epsV 2.7.8.12 S glycosyl transferase family 2
HDHCIICM_01193 1.5e-123 S Alpha/beta hydrolase family
HDHCIICM_01194 9.1e-62
HDHCIICM_01195 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDHCIICM_01196 4.3e-193 S CAAX protease self-immunity
HDHCIICM_01197 3.7e-241 cycA E Amino acid permease
HDHCIICM_01198 1.1e-113 luxT K Bacterial regulatory proteins, tetR family
HDHCIICM_01199 5.6e-139
HDHCIICM_01200 3e-284 S Cysteine-rich secretory protein family
HDHCIICM_01201 2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDHCIICM_01202 8.9e-93
HDHCIICM_01203 2.8e-269 yjcE P Sodium proton antiporter
HDHCIICM_01204 1.2e-184 yibE S overlaps another CDS with the same product name
HDHCIICM_01205 4.9e-118 yibF S overlaps another CDS with the same product name
HDHCIICM_01206 6.7e-153 I alpha/beta hydrolase fold
HDHCIICM_01207 0.0 G Belongs to the glycosyl hydrolase 31 family
HDHCIICM_01208 1.5e-129 XK27_08435 K UTRA
HDHCIICM_01209 9.3e-217 agaS G SIS domain
HDHCIICM_01210 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDHCIICM_01211 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HDHCIICM_01212 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
HDHCIICM_01213 1.6e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HDHCIICM_01214 3.6e-67 2.7.1.191 G PTS system fructose IIA component
HDHCIICM_01215 5.6e-17 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_01216 2.1e-200 S zinc-ribbon domain
HDHCIICM_01217 1e-182
HDHCIICM_01218 7.4e-88 ntd 2.4.2.6 F Nucleoside
HDHCIICM_01219 1.9e-98 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDHCIICM_01220 8.9e-125 XK27_08440 K UTRA domain
HDHCIICM_01221 1.3e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
HDHCIICM_01222 3.8e-87 uspA T universal stress protein
HDHCIICM_01224 8.3e-168 phnD P Phosphonate ABC transporter
HDHCIICM_01225 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDHCIICM_01226 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HDHCIICM_01227 9.2e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HDHCIICM_01228 7.3e-83
HDHCIICM_01229 6.2e-276 S Calcineurin-like phosphoesterase
HDHCIICM_01230 0.0 asnB 6.3.5.4 E Asparagine synthase
HDHCIICM_01231 2.8e-265 yxbA 6.3.1.12 S ATP-grasp enzyme
HDHCIICM_01232 1.6e-59
HDHCIICM_01233 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDHCIICM_01234 2e-137 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDHCIICM_01235 3.5e-103 S Iron-sulfur cluster assembly protein
HDHCIICM_01236 5.8e-222 XK27_04775 S PAS domain
HDHCIICM_01237 2.5e-272 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01238 0.0 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01239 6.9e-60 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01240 2.1e-101 UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01241 4.2e-228 yttB EGP Major facilitator Superfamily
HDHCIICM_01242 7.2e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HDHCIICM_01243 1.5e-11 D nuclear chromosome segregation
HDHCIICM_01244 9.1e-166 D nuclear chromosome segregation
HDHCIICM_01245 2e-135 rpl K Helix-turn-helix domain, rpiR family
HDHCIICM_01246 1e-162 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HDHCIICM_01247 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDHCIICM_01248 0.0 pepO 3.4.24.71 O Peptidase family M13
HDHCIICM_01249 5.8e-308 S Bacterial membrane protein, YfhO
HDHCIICM_01250 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HDHCIICM_01251 0.0 kup P Transport of potassium into the cell
HDHCIICM_01252 0.0 kup P Transport of potassium into the cell
HDHCIICM_01253 3.9e-72
HDHCIICM_01254 2.6e-101
HDHCIICM_01255 5e-28
HDHCIICM_01256 1.4e-34 S Protein of unknown function (DUF2922)
HDHCIICM_01257 5.4e-251 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDHCIICM_01258 1.7e-56 lysA2 M Glycosyl hydrolases family 25
HDHCIICM_01259 4.1e-154 lysA2 M Glycosyl hydrolases family 25
HDHCIICM_01260 1.1e-62 lysA2 M Glycosyl hydrolases family 25
HDHCIICM_01261 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
HDHCIICM_01262 0.0 yjbQ P TrkA C-terminal domain protein
HDHCIICM_01263 2.7e-177 S Oxidoreductase family, NAD-binding Rossmann fold
HDHCIICM_01264 2.9e-129
HDHCIICM_01265 2.9e-148
HDHCIICM_01266 1.4e-74 S PAS domain
HDHCIICM_01267 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDHCIICM_01268 2.3e-57 V Abi-like protein
HDHCIICM_01269 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDHCIICM_01270 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
HDHCIICM_01271 2.3e-178 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HDHCIICM_01272 1e-117
HDHCIICM_01273 1.9e-150 glcU U sugar transport
HDHCIICM_01274 2e-171 yqhA G Aldose 1-epimerase
HDHCIICM_01275 1.8e-193 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDHCIICM_01276 7.4e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDHCIICM_01277 0.0 XK27_08315 M Sulfatase
HDHCIICM_01278 9e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDHCIICM_01280 6.1e-257 pepC 3.4.22.40 E aminopeptidase
HDHCIICM_01281 7e-121 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDHCIICM_01282 4.2e-41 ps301 K sequence-specific DNA binding
HDHCIICM_01283 1.9e-255 pepC 3.4.22.40 E aminopeptidase
HDHCIICM_01284 7.7e-43
HDHCIICM_01285 3.4e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDHCIICM_01286 2.8e-73 hsp O Belongs to the small heat shock protein (HSP20) family
HDHCIICM_01287 1.3e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_01288 4.9e-82
HDHCIICM_01289 5.3e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01290 2.4e-127 yydK K UTRA
HDHCIICM_01291 5.3e-58 S Domain of unknown function (DUF3284)
HDHCIICM_01292 6.4e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_01293 1.2e-132 gmuR K UTRA
HDHCIICM_01294 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HDHCIICM_01295 6.5e-27
HDHCIICM_01296 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDHCIICM_01297 4.4e-68 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01298 1.9e-189 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01299 3.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_01300 3.7e-154 ypbG 2.7.1.2 GK ROK family
HDHCIICM_01301 4.2e-113
HDHCIICM_01303 1.2e-111 E Belongs to the SOS response-associated peptidase family
HDHCIICM_01304 7.5e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDHCIICM_01305 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
HDHCIICM_01306 2.6e-98 S TPM domain
HDHCIICM_01307 1.6e-92 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HDHCIICM_01308 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDHCIICM_01309 2e-146 tatD L hydrolase, TatD family
HDHCIICM_01310 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDHCIICM_01311 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDHCIICM_01312 7.4e-36 veg S Biofilm formation stimulator VEG
HDHCIICM_01313 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDHCIICM_01314 5.9e-218 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDHCIICM_01315 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDHCIICM_01316 5.8e-177 yvdE K helix_turn _helix lactose operon repressor
HDHCIICM_01317 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HDHCIICM_01318 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HDHCIICM_01319 9e-251 yfnA E Amino Acid
HDHCIICM_01320 0.0 clpE2 O AAA domain (Cdc48 subfamily)
HDHCIICM_01321 6.5e-157 S Alpha/beta hydrolase of unknown function (DUF915)
HDHCIICM_01322 2.8e-241 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01323 9.2e-39
HDHCIICM_01324 5.2e-215 lmrP E Major Facilitator Superfamily
HDHCIICM_01325 7.7e-174 pbpX2 V Beta-lactamase
HDHCIICM_01326 4.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDHCIICM_01327 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHCIICM_01328 5.5e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HDHCIICM_01329 1.6e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDHCIICM_01331 1e-44
HDHCIICM_01332 8.6e-199 ywhK S Membrane
HDHCIICM_01334 6e-55
HDHCIICM_01336 1.1e-35
HDHCIICM_01337 2.7e-85 ykuL S (CBS) domain
HDHCIICM_01338 0.0 cadA P P-type ATPase
HDHCIICM_01339 3.5e-200 napA P Sodium/hydrogen exchanger family
HDHCIICM_01341 9.4e-281 V ABC transporter transmembrane region
HDHCIICM_01342 2.9e-159 mutR K Helix-turn-helix XRE-family like proteins
HDHCIICM_01343 6.2e-28
HDHCIICM_01344 4.8e-32
HDHCIICM_01345 2.1e-30
HDHCIICM_01346 3.8e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDHCIICM_01347 3.8e-157 S Protein of unknown function (DUF979)
HDHCIICM_01348 2.3e-114 S Protein of unknown function (DUF969)
HDHCIICM_01349 5.2e-233 G PTS system sugar-specific permease component
HDHCIICM_01350 4.5e-269 G PTS system Galactitol-specific IIC component
HDHCIICM_01351 2.6e-94 S Protein of unknown function (DUF1440)
HDHCIICM_01352 6.5e-103 S CAAX protease self-immunity
HDHCIICM_01353 9.6e-195 S DUF218 domain
HDHCIICM_01354 0.0 macB_3 V ABC transporter, ATP-binding protein
HDHCIICM_01355 1.1e-269 cydA 1.10.3.14 C ubiquinol oxidase
HDHCIICM_01356 2.5e-181 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HDHCIICM_01357 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDHCIICM_01358 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDHCIICM_01359 1.1e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HDHCIICM_01360 1.1e-167 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HDHCIICM_01361 1.9e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
HDHCIICM_01362 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
HDHCIICM_01363 2.6e-176 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HDHCIICM_01364 2e-99 G PTS system sorbose-specific iic component
HDHCIICM_01365 2.9e-119 G PTS system mannose/fructose/sorbose family IID component
HDHCIICM_01366 1.3e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
HDHCIICM_01367 3.2e-88 blaA6 V Beta-lactamase
HDHCIICM_01368 5.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDHCIICM_01369 4.1e-130 3.5.2.6 V Beta-lactamase enzyme family
HDHCIICM_01370 5.2e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDHCIICM_01371 1.2e-132 S membrane transporter protein
HDHCIICM_01372 2.2e-27 G PTS system fructose IIA component
HDHCIICM_01373 9.1e-123 G PTS system mannose/fructose/sorbose family IID component
HDHCIICM_01374 1.7e-92 agaC G PTS system sorbose-specific iic component
HDHCIICM_01375 4.6e-150 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
HDHCIICM_01377 3.6e-19 S PD-(D/E)XK nuclease family transposase
HDHCIICM_01378 1.7e-159 yeaE S Aldo/keto reductase family
HDHCIICM_01379 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDHCIICM_01380 1.7e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDHCIICM_01381 4.1e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDHCIICM_01382 1.1e-236 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDHCIICM_01383 1.2e-231 pbuG S permease
HDHCIICM_01385 7.2e-87 K helix_turn_helix, mercury resistance
HDHCIICM_01386 1.7e-230 pbuG S permease
HDHCIICM_01387 3.8e-20 I bis(5'-adenosyl)-triphosphatase activity
HDHCIICM_01388 5.2e-227 pbuG S permease
HDHCIICM_01389 1.2e-28 K Bacteriophage CI repressor helix-turn-helix domain
HDHCIICM_01390 1e-64 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDHCIICM_01391 3.7e-207 bglF_1 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDHCIICM_01392 3.1e-222 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HDHCIICM_01393 5.3e-77 scrR K Periplasmic binding protein domain
HDHCIICM_01394 5.3e-85
HDHCIICM_01395 8.1e-73 atkY K Penicillinase repressor
HDHCIICM_01396 9.5e-62 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDHCIICM_01397 9.2e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDHCIICM_01398 0.0 copA 3.6.3.54 P P-type ATPase
HDHCIICM_01399 3.9e-151 ropB K Helix-turn-helix XRE-family like proteins
HDHCIICM_01400 0.0 pepO 3.4.24.71 O Peptidase family M13
HDHCIICM_01401 2.7e-285 E Amino acid permease
HDHCIICM_01402 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HDHCIICM_01403 1.4e-247 ynbB 4.4.1.1 P aluminum resistance
HDHCIICM_01404 3.8e-70 K Acetyltransferase (GNAT) domain
HDHCIICM_01405 7.4e-234 EGP Sugar (and other) transporter
HDHCIICM_01406 6.9e-63 S Iron-sulphur cluster biosynthesis
HDHCIICM_01407 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDHCIICM_01408 2.9e-196 V ABC-type multidrug transport system, ATPase and permease components
HDHCIICM_01409 4.8e-200 P ABC transporter
HDHCIICM_01410 6.3e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HDHCIICM_01411 1.3e-104
HDHCIICM_01412 3.4e-186 L COG2963 Transposase and inactivated derivatives
HDHCIICM_01413 2.4e-240 EGP Sugar (and other) transporter
HDHCIICM_01414 2.8e-105 pncA Q Isochorismatase family
HDHCIICM_01415 1e-279 clcA P chloride
HDHCIICM_01416 8.3e-71 K Helix-turn-helix domain, rpiR family
HDHCIICM_01417 3.1e-60 E GDSL-like Lipase/Acylhydrolase
HDHCIICM_01418 1.4e-161 M1-530 S Protein of unknown function (DUF4127)
HDHCIICM_01419 1.4e-72 S haloacid dehalogenase-like hydrolase
HDHCIICM_01420 4.3e-178 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01421 1e-252 lctP C L-lactate permease
HDHCIICM_01422 5.1e-134 znuB U ABC 3 transport family
HDHCIICM_01423 2.8e-117 fhuC P ABC transporter
HDHCIICM_01424 2.9e-157 psaA P Belongs to the bacterial solute-binding protein 9 family
HDHCIICM_01425 1.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDHCIICM_01426 1.3e-137 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HDHCIICM_01427 0.0 M domain protein
HDHCIICM_01428 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HDHCIICM_01429 2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDHCIICM_01430 3.4e-135 fruR K DeoR C terminal sensor domain
HDHCIICM_01431 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HDHCIICM_01432 1.1e-220 natB CP ABC-2 family transporter protein
HDHCIICM_01433 1.3e-165 natA S ABC transporter, ATP-binding protein
HDHCIICM_01434 2.6e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDHCIICM_01435 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDHCIICM_01436 2.9e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HDHCIICM_01437 9.6e-121 K response regulator
HDHCIICM_01438 0.0 V ABC transporter
HDHCIICM_01439 2.5e-295 V ABC transporter, ATP-binding protein
HDHCIICM_01440 3.7e-143 XK27_01040 S Protein of unknown function (DUF1129)
HDHCIICM_01441 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDHCIICM_01442 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
HDHCIICM_01443 2.2e-154 spo0J K Belongs to the ParB family
HDHCIICM_01444 1.3e-137 soj D Sporulation initiation inhibitor
HDHCIICM_01445 2.1e-144 noc K Belongs to the ParB family
HDHCIICM_01446 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HDHCIICM_01447 4.1e-95 cvpA S Colicin V production protein
HDHCIICM_01448 2.1e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDHCIICM_01449 8.3e-148 3.1.3.48 T Tyrosine phosphatase family
HDHCIICM_01450 8.6e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HDHCIICM_01451 1.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
HDHCIICM_01452 4.5e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HDHCIICM_01453 1e-108 K WHG domain
HDHCIICM_01454 8e-38
HDHCIICM_01455 1.8e-260 pipD E Dipeptidase
HDHCIICM_01456 1.7e-295 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_01457 3.8e-297 2.7.1.211 G phosphotransferase system
HDHCIICM_01458 4.2e-158 K CAT RNA binding domain
HDHCIICM_01459 1.2e-115 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HDHCIICM_01460 1.1e-173 hrtB V ABC transporter permease
HDHCIICM_01461 1.9e-92 ygfC K Bacterial regulatory proteins, tetR family
HDHCIICM_01462 1.3e-110 G phosphoglycerate mutase
HDHCIICM_01463 5.2e-113 G Phosphoglycerate mutase family
HDHCIICM_01464 6.5e-139 aroD S Alpha/beta hydrolase family
HDHCIICM_01465 7.7e-106 S Protein of unknown function (DUF975)
HDHCIICM_01466 7.3e-138 S Belongs to the UPF0246 family
HDHCIICM_01467 2.9e-52
HDHCIICM_01468 6.7e-130
HDHCIICM_01469 6.2e-160 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HDHCIICM_01470 1.4e-248 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HDHCIICM_01471 4.3e-44 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HDHCIICM_01472 3.4e-143 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HDHCIICM_01473 6.3e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
HDHCIICM_01474 1.3e-170 2.7.7.12 C Domain of unknown function (DUF4931)
HDHCIICM_01475 1.4e-53 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
HDHCIICM_01476 2.4e-156
HDHCIICM_01477 3e-226 mdtG EGP Major facilitator Superfamily
HDHCIICM_01478 1.2e-123 puuD S peptidase C26
HDHCIICM_01479 5.8e-294 V ABC transporter transmembrane region
HDHCIICM_01480 4.5e-91 ymdB S Macro domain protein
HDHCIICM_01481 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HDHCIICM_01482 2.3e-297 scrB 3.2.1.26 GH32 G invertase
HDHCIICM_01483 1.2e-185 scrR K Transcriptional regulator, LacI family
HDHCIICM_01484 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
HDHCIICM_01485 5.8e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDHCIICM_01486 3.5e-131 cobQ S glutamine amidotransferase
HDHCIICM_01487 4.2e-256 yfnA E Amino Acid
HDHCIICM_01488 3.5e-163 EG EamA-like transporter family
HDHCIICM_01489 1.5e-186 asnA 6.3.1.1 F aspartate--ammonia ligase
HDHCIICM_01490 5.3e-223 S CAAX protease self-immunity
HDHCIICM_01491 4.7e-239 steT_1 E amino acid
HDHCIICM_01492 4.5e-137 puuD S peptidase C26
HDHCIICM_01493 3.7e-220 yifK E Amino acid permease
HDHCIICM_01494 5.8e-250 yifK E Amino acid permease
HDHCIICM_01495 1.8e-65 manO S Domain of unknown function (DUF956)
HDHCIICM_01496 5.6e-172 manN G system, mannose fructose sorbose family IID component
HDHCIICM_01497 1.3e-124 manY G PTS system
HDHCIICM_01498 9.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HDHCIICM_01499 2.8e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDHCIICM_01500 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDHCIICM_01501 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDHCIICM_01502 9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDHCIICM_01503 1.4e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDHCIICM_01504 3.9e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDHCIICM_01505 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HDHCIICM_01506 1.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDHCIICM_01507 9.4e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDHCIICM_01508 3.9e-19 yaaA S S4 domain
HDHCIICM_01509 2.2e-207 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDHCIICM_01510 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDHCIICM_01511 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDHCIICM_01512 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HDHCIICM_01513 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDHCIICM_01514 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDHCIICM_01515 7.2e-156 corA P CorA-like Mg2+ transporter protein
HDHCIICM_01516 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDHCIICM_01517 1.1e-75 rplI J Binds to the 23S rRNA
HDHCIICM_01518 3.3e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDHCIICM_01519 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HDHCIICM_01520 1.9e-217 I Protein of unknown function (DUF2974)
HDHCIICM_01521 0.0
HDHCIICM_01522 1.7e-117 yhiD S MgtC family
HDHCIICM_01524 5.7e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HDHCIICM_01525 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HDHCIICM_01526 4.9e-85 S Protein of unknown function (DUF3278)
HDHCIICM_01527 3.8e-193 S Aldo keto reductase
HDHCIICM_01529 5.2e-220 S Sterol carrier protein domain
HDHCIICM_01530 3e-116 ywnB S NAD(P)H-binding
HDHCIICM_01531 7.2e-109 S Protein of unknown function (DUF975)
HDHCIICM_01532 4.9e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDHCIICM_01533 6.8e-153 yitS S EDD domain protein, DegV family
HDHCIICM_01534 2.2e-19
HDHCIICM_01535 0.0 tetP J elongation factor G
HDHCIICM_01536 8e-163 P CorA-like Mg2+ transporter protein
HDHCIICM_01538 4.2e-40 S Transglycosylase associated protein
HDHCIICM_01539 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HDHCIICM_01540 0.0 L Helicase C-terminal domain protein
HDHCIICM_01541 1.3e-157 S Alpha beta hydrolase
HDHCIICM_01542 5.2e-40
HDHCIICM_01543 1e-166 K AI-2E family transporter
HDHCIICM_01544 2.1e-244 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HDHCIICM_01545 6.8e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDHCIICM_01546 5.2e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HDHCIICM_01547 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDHCIICM_01548 3.7e-132 S domain, Protein
HDHCIICM_01549 7.8e-294 S domain, Protein
HDHCIICM_01550 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01551 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HDHCIICM_01552 0.0 3.1.31.1 M domain protein
HDHCIICM_01553 1.6e-266 E amino acid
HDHCIICM_01554 2.3e-170 K LysR substrate binding domain
HDHCIICM_01555 0.0 1.3.5.4 C FAD binding domain
HDHCIICM_01556 4e-243 brnQ U Component of the transport system for branched-chain amino acids
HDHCIICM_01557 2.3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDHCIICM_01558 6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HDHCIICM_01559 3.2e-88 S Peptidase propeptide and YPEB domain
HDHCIICM_01560 1.3e-184 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDHCIICM_01561 1.1e-248 yhjX_2 P Major Facilitator Superfamily
HDHCIICM_01562 3.9e-235 yhjX_2 P Major Facilitator Superfamily
HDHCIICM_01563 6.7e-164 arbZ I Phosphate acyltransferases
HDHCIICM_01564 5.5e-183 arbY M Glycosyl transferase family 8
HDHCIICM_01565 7.2e-183 arbY M Glycosyl transferase family 8
HDHCIICM_01566 3.2e-155 arbx M Glycosyl transferase family 8
HDHCIICM_01567 6.6e-150 arbV 2.3.1.51 I Acyl-transferase
HDHCIICM_01569 9.3e-08 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDHCIICM_01570 2.2e-74 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDHCIICM_01571 2.6e-23 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDHCIICM_01572 1.4e-39 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDHCIICM_01574 3.3e-57 fhaB M Rib/alpha-like repeat
HDHCIICM_01575 0.0 pepF E oligoendopeptidase F
HDHCIICM_01576 1.5e-211 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDHCIICM_01577 4e-38
HDHCIICM_01578 5.5e-62
HDHCIICM_01579 5.4e-281 S ABC transporter, ATP-binding protein
HDHCIICM_01580 1.3e-137 thrE S Putative threonine/serine exporter
HDHCIICM_01581 4e-78 S Threonine/Serine exporter, ThrE
HDHCIICM_01582 1.8e-40
HDHCIICM_01583 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDHCIICM_01584 3.8e-79
HDHCIICM_01585 7.4e-180 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDHCIICM_01586 2.9e-81 nrdI F NrdI Flavodoxin like
HDHCIICM_01587 2.6e-109
HDHCIICM_01588 1.1e-273 S O-antigen ligase like membrane protein
HDHCIICM_01589 9e-44
HDHCIICM_01590 8.4e-99 gmk2 2.7.4.8 F Guanylate kinase
HDHCIICM_01591 5.4e-92 M NlpC P60 family protein
HDHCIICM_01592 2.8e-232 S Putative peptidoglycan binding domain
HDHCIICM_01593 1.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDHCIICM_01594 2.8e-279 E amino acid
HDHCIICM_01595 8.2e-134 cysA V ABC transporter, ATP-binding protein
HDHCIICM_01596 0.0 V FtsX-like permease family
HDHCIICM_01597 3.7e-122 pgm3 G Phosphoglycerate mutase family
HDHCIICM_01598 5.3e-25
HDHCIICM_01599 2.1e-52
HDHCIICM_01600 1e-147 xth 3.1.11.2 L exodeoxyribonuclease III
HDHCIICM_01601 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HDHCIICM_01602 5.9e-126 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDHCIICM_01603 6.2e-143 rpiR1 K Helix-turn-helix domain, rpiR family
HDHCIICM_01604 7.7e-168 3.4.16.4 M ErfK YbiS YcfS YnhG
HDHCIICM_01605 1.2e-55 3.4.16.4 M ErfK YbiS YcfS YnhG
HDHCIICM_01606 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
HDHCIICM_01608 1.6e-114 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HDHCIICM_01609 0.0 helD 3.6.4.12 L DNA helicase
HDHCIICM_01610 8.8e-133 yvpB S Peptidase_C39 like family
HDHCIICM_01611 1.9e-109 K helix_turn _helix lactose operon repressor
HDHCIICM_01612 7.9e-37 rpe 5.1.3.1 G Ribulose-phosphate 3 epimerase family
HDHCIICM_01613 3e-43 rpe 5.1.3.1 G Ribulose-phosphate 3 epimerase family
HDHCIICM_01614 2.4e-71 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HDHCIICM_01615 1.1e-144 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01616 5.9e-92 O peptidase U32
HDHCIICM_01617 1.7e-167 3.2.1.86 GT1 G beta-glucosidase activity
HDHCIICM_01618 2.3e-122 K Helix-turn-helix domain, rpiR family
HDHCIICM_01619 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HDHCIICM_01620 4.5e-244 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDHCIICM_01621 6.8e-104 E GDSL-like Lipase/Acylhydrolase
HDHCIICM_01622 6.7e-164 coaA 2.7.1.33 F Pantothenic acid kinase
HDHCIICM_01623 3.2e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDHCIICM_01624 1.5e-12 fhaB M Rib/alpha-like repeat
HDHCIICM_01625 1.5e-45 fhaB M Rib/alpha-like repeat
HDHCIICM_01626 7.1e-173 fhaB M Rib/alpha-like repeat
HDHCIICM_01627 2.1e-149 licT K CAT RNA binding domain
HDHCIICM_01628 0.0 bglP 2.7.1.211 G phosphotransferase system
HDHCIICM_01629 5e-284 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDHCIICM_01630 1.9e-46
HDHCIICM_01631 2.9e-160 EG EamA-like transporter family
HDHCIICM_01632 6e-57 S PFAM Archaeal ATPase
HDHCIICM_01633 0.0 oppA E ABC transporter substrate-binding protein
HDHCIICM_01634 0.0 uvrA3 L excinuclease ABC, A subunit
HDHCIICM_01635 5e-69
HDHCIICM_01636 8e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDHCIICM_01637 1.2e-213 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HDHCIICM_01638 8.7e-238 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDHCIICM_01639 8.7e-128 S PAS domain
HDHCIICM_01640 6.8e-153 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDHCIICM_01641 2e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDHCIICM_01642 0.0 M domain protein
HDHCIICM_01643 6.3e-145 pnuC H nicotinamide mononucleotide transporter
HDHCIICM_01644 2.5e-89 S PAS domain
HDHCIICM_01645 8e-246 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDHCIICM_01646 1.3e-73 S Protein of unknown function (DUF3290)
HDHCIICM_01647 3.1e-113 yviA S Protein of unknown function (DUF421)
HDHCIICM_01648 5.8e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDHCIICM_01649 5.6e-183 dnaQ 2.7.7.7 L EXOIII
HDHCIICM_01650 1.2e-200 ltrA S Bacterial low temperature requirement A protein (LtrA)
HDHCIICM_01651 1.3e-148 dkg S reductase
HDHCIICM_01652 5.7e-131 endA F DNA RNA non-specific endonuclease
HDHCIICM_01653 5.6e-55 pipD E Dipeptidase
HDHCIICM_01654 4.7e-207 pipD E Dipeptidase
HDHCIICM_01655 2.7e-202 malK P ATPases associated with a variety of cellular activities
HDHCIICM_01656 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
HDHCIICM_01657 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
HDHCIICM_01658 5.3e-253 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HDHCIICM_01659 3e-240 G Bacterial extracellular solute-binding protein
HDHCIICM_01660 6.2e-50 ypaA S Protein of unknown function (DUF1304)
HDHCIICM_01661 4.8e-76 yybA 2.3.1.57 K Transcriptional regulator
HDHCIICM_01662 7.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HDHCIICM_01663 3.4e-79 yjcF S Acetyltransferase (GNAT) domain
HDHCIICM_01664 5.9e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HDHCIICM_01665 1.1e-164 3.5.2.6 V Beta-lactamase enzyme family
HDHCIICM_01666 1.2e-97 yobS K Bacterial regulatory proteins, tetR family
HDHCIICM_01667 0.0 ydgH S MMPL family
HDHCIICM_01668 4.9e-132 cof S haloacid dehalogenase-like hydrolase
HDHCIICM_01669 8.7e-122 S SNARE associated Golgi protein
HDHCIICM_01670 6e-180
HDHCIICM_01671 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HDHCIICM_01672 9.9e-144 hipB K Helix-turn-helix
HDHCIICM_01673 6e-151 I alpha/beta hydrolase fold
HDHCIICM_01674 1.5e-106 yjbF S SNARE associated Golgi protein
HDHCIICM_01675 6.8e-101 J Acetyltransferase (GNAT) domain
HDHCIICM_01676 5.2e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDHCIICM_01677 1.6e-180 lacR K Transcriptional regulator
HDHCIICM_01678 6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDHCIICM_01679 3.7e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDHCIICM_01680 1.1e-191 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDHCIICM_01681 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDHCIICM_01682 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDHCIICM_01683 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDHCIICM_01684 4e-90 S Short repeat of unknown function (DUF308)
HDHCIICM_01685 6e-160 rapZ S Displays ATPase and GTPase activities
HDHCIICM_01686 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDHCIICM_01687 1.8e-170 whiA K May be required for sporulation
HDHCIICM_01688 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDHCIICM_01689 5.8e-277 ycaM E amino acid
HDHCIICM_01691 2.3e-187 cggR K Putative sugar-binding domain
HDHCIICM_01692 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDHCIICM_01693 1.8e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDHCIICM_01694 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDHCIICM_01695 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDHCIICM_01696 2.5e-28 secG U Preprotein translocase
HDHCIICM_01697 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDHCIICM_01698 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDHCIICM_01699 1e-107 3.2.2.20 K acetyltransferase
HDHCIICM_01701 6.6e-91
HDHCIICM_01702 8.3e-93
HDHCIICM_01703 4e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
HDHCIICM_01704 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDHCIICM_01705 1.2e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDHCIICM_01706 6.5e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HDHCIICM_01707 6.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
HDHCIICM_01708 3.8e-165 murB 1.3.1.98 M Cell wall formation
HDHCIICM_01709 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDHCIICM_01710 4.6e-130 potB P ABC transporter permease
HDHCIICM_01711 4.2e-136 potC P ABC transporter permease
HDHCIICM_01712 9.5e-208 potD P ABC transporter
HDHCIICM_01713 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDHCIICM_01714 8.1e-174 ybbR S YbbR-like protein
HDHCIICM_01715 5.9e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDHCIICM_01716 8.4e-148 S Sucrose-6F-phosphate phosphohydrolase
HDHCIICM_01717 2.9e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDHCIICM_01718 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDHCIICM_01719 5.2e-178 S Putative adhesin
HDHCIICM_01720 1.1e-114
HDHCIICM_01721 3.6e-148 yisY 1.11.1.10 S Alpha/beta hydrolase family
HDHCIICM_01722 1.7e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HDHCIICM_01723 9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDHCIICM_01724 7.3e-97 S VanZ like family
HDHCIICM_01725 1.7e-131 yebC K Transcriptional regulatory protein
HDHCIICM_01726 6.5e-179 comGA NU Type II IV secretion system protein
HDHCIICM_01727 4.7e-177 comGB NU type II secretion system
HDHCIICM_01728 1.8e-36 comGC U Required for transformation and DNA binding
HDHCIICM_01729 3.7e-67
HDHCIICM_01731 4.7e-88 comGF U Putative Competence protein ComGF
HDHCIICM_01732 2.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HDHCIICM_01733 3.6e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDHCIICM_01735 1.9e-150 L Belongs to the 'phage' integrase family
HDHCIICM_01736 1.1e-60 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDHCIICM_01737 8.9e-33 S Domain of unknown function (DUF4160)
HDHCIICM_01738 8.4e-34
HDHCIICM_01740 1.1e-63 doc S Fic/DOC family
HDHCIICM_01741 4.1e-37
HDHCIICM_01742 2.3e-171 K Helix-turn-helix
HDHCIICM_01744 2.6e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDHCIICM_01745 1.2e-127 K DNA-binding helix-turn-helix protein
HDHCIICM_01746 1.3e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDHCIICM_01747 1.6e-233 pbuX F xanthine permease
HDHCIICM_01748 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDHCIICM_01749 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDHCIICM_01750 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDHCIICM_01751 1.7e-72 S Domain of unknown function (DUF1934)
HDHCIICM_01752 1.7e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDHCIICM_01753 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HDHCIICM_01754 1.3e-154 malG P ABC transporter permease
HDHCIICM_01755 7.2e-253 malF P Binding-protein-dependent transport system inner membrane component
HDHCIICM_01756 8.3e-131 malE G Bacterial extracellular solute-binding protein
HDHCIICM_01757 2.3e-87 malE G Bacterial extracellular solute-binding protein
HDHCIICM_01758 3.6e-210 msmX P Belongs to the ABC transporter superfamily
HDHCIICM_01759 6e-112 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDHCIICM_01760 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDHCIICM_01761 0.0 lhr L DEAD DEAH box helicase
HDHCIICM_01762 5.6e-250 P P-loop Domain of unknown function (DUF2791)
HDHCIICM_01763 0.0 S TerB-C domain
HDHCIICM_01764 6.4e-104 4.1.1.44 S Carboxymuconolactone decarboxylase family
HDHCIICM_01765 9.6e-71
HDHCIICM_01766 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDHCIICM_01767 2.9e-233 cycA E Amino acid permease
HDHCIICM_01768 2.5e-214 rgpA GT4 M Domain of unknown function (DUF1972)
HDHCIICM_01769 3.4e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
HDHCIICM_01770 5.2e-142 rgpC GM Transport permease protein
HDHCIICM_01771 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDHCIICM_01772 4.3e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDHCIICM_01773 0.0 rgpF M Rhamnan synthesis protein F
HDHCIICM_01774 1.6e-155 rfbJ M Glycosyl transferase family 2
HDHCIICM_01775 2.1e-45 M Psort location CytoplasmicMembrane, score
HDHCIICM_01776 1.4e-167
HDHCIICM_01777 2.3e-108 P Cobalt transport protein
HDHCIICM_01778 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDHCIICM_01779 7e-183 htrA 3.4.21.107 O serine protease
HDHCIICM_01780 1.5e-149 vicX 3.1.26.11 S domain protein
HDHCIICM_01781 1.4e-142 yycI S YycH protein
HDHCIICM_01782 3.2e-253 yycH S YycH protein
HDHCIICM_01783 0.0 vicK 2.7.13.3 T Histidine kinase
HDHCIICM_01784 1.2e-129 K response regulator
HDHCIICM_01785 2.8e-134 J Domain of unknown function (DUF4041)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)