ORF_ID e_value Gene_name EC_number CAZy COGs Description
GHJEJHIM_00001 1.1e-45 azlD E Branched-chain amino acid transport protein (AzlD)
GHJEJHIM_00002 2.4e-195 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
GHJEJHIM_00003 5.2e-95 ptpA 3.1.3.48 T low molecular weight
GHJEJHIM_00004 1.7e-127 folA 1.5.1.3 H dihydrofolate reductase
GHJEJHIM_00005 7.3e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GHJEJHIM_00006 3.2e-71 attW O OsmC-like protein
GHJEJHIM_00007 1.6e-191 T Universal stress protein family
GHJEJHIM_00008 6e-106 M NlpC/P60 family
GHJEJHIM_00009 9.7e-178 usp 3.5.1.28 CBM50 S CHAP domain
GHJEJHIM_00010 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GHJEJHIM_00011 2.6e-39
GHJEJHIM_00012 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GHJEJHIM_00013 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
GHJEJHIM_00014 4.2e-07 EGP Major facilitator Superfamily
GHJEJHIM_00015 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHJEJHIM_00016 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
GHJEJHIM_00017 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GHJEJHIM_00019 4.3e-217 araJ EGP Major facilitator Superfamily
GHJEJHIM_00020 0.0 S Domain of unknown function (DUF4037)
GHJEJHIM_00021 1.5e-112 S Protein of unknown function (DUF4125)
GHJEJHIM_00022 7.3e-135
GHJEJHIM_00023 3.6e-289 pspC KT PspC domain
GHJEJHIM_00024 8.9e-273 tcsS3 KT PspC domain
GHJEJHIM_00025 9.2e-126 degU K helix_turn_helix, Lux Regulon
GHJEJHIM_00026 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GHJEJHIM_00028 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
GHJEJHIM_00029 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
GHJEJHIM_00030 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GHJEJHIM_00031 1.8e-95
GHJEJHIM_00033 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
GHJEJHIM_00035 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GHJEJHIM_00036 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
GHJEJHIM_00037 1e-212 I Diacylglycerol kinase catalytic domain
GHJEJHIM_00038 1.3e-151 arbG K CAT RNA binding domain
GHJEJHIM_00039 0.0 crr G pts system, glucose-specific IIABC component
GHJEJHIM_00040 4.6e-42 M Spy0128-like isopeptide containing domain
GHJEJHIM_00041 3.4e-55 M Spy0128-like isopeptide containing domain
GHJEJHIM_00044 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
GHJEJHIM_00045 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHJEJHIM_00046 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
GHJEJHIM_00047 4.6e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHJEJHIM_00048 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GHJEJHIM_00050 1e-105
GHJEJHIM_00051 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHJEJHIM_00052 8.5e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
GHJEJHIM_00053 2.1e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GHJEJHIM_00054 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GHJEJHIM_00055 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHJEJHIM_00056 2.8e-188 nusA K Participates in both transcription termination and antitermination
GHJEJHIM_00057 7.6e-164
GHJEJHIM_00058 1.1e-145 L Transposase and inactivated derivatives
GHJEJHIM_00060 1.3e-153 E Transglutaminase/protease-like homologues
GHJEJHIM_00061 0.0 gcs2 S A circularly permuted ATPgrasp
GHJEJHIM_00062 8.3e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GHJEJHIM_00063 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
GHJEJHIM_00064 2.3e-63 rplQ J Ribosomal protein L17
GHJEJHIM_00065 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHJEJHIM_00066 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GHJEJHIM_00067 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GHJEJHIM_00068 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GHJEJHIM_00069 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GHJEJHIM_00070 3.2e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHJEJHIM_00071 4e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GHJEJHIM_00072 2.7e-63 rplO J binds to the 23S rRNA
GHJEJHIM_00073 1e-24 rpmD J Ribosomal protein L30p/L7e
GHJEJHIM_00074 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GHJEJHIM_00075 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GHJEJHIM_00076 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GHJEJHIM_00077 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GHJEJHIM_00078 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHJEJHIM_00079 9.2e-101 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GHJEJHIM_00080 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GHJEJHIM_00081 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GHJEJHIM_00082 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GHJEJHIM_00083 4.2e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
GHJEJHIM_00084 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GHJEJHIM_00085 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GHJEJHIM_00086 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GHJEJHIM_00087 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GHJEJHIM_00088 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GHJEJHIM_00089 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GHJEJHIM_00090 1.9e-113 rplD J Forms part of the polypeptide exit tunnel
GHJEJHIM_00091 1.1e-115 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GHJEJHIM_00092 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
GHJEJHIM_00093 1.4e-58 ywiC S YwiC-like protein
GHJEJHIM_00094 4.3e-86 ywiC S YwiC-like protein
GHJEJHIM_00095 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
GHJEJHIM_00096 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GHJEJHIM_00097 3.7e-232 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
GHJEJHIM_00098 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GHJEJHIM_00099 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
GHJEJHIM_00100 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GHJEJHIM_00101 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
GHJEJHIM_00102 3e-120
GHJEJHIM_00103 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
GHJEJHIM_00104 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
GHJEJHIM_00106 8.7e-240 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHJEJHIM_00107 6.1e-224 dapC E Aminotransferase class I and II
GHJEJHIM_00108 9e-61 fdxA C 4Fe-4S binding domain
GHJEJHIM_00109 4.5e-214 murB 1.3.1.98 M Cell wall formation
GHJEJHIM_00110 1.9e-25 rpmG J Ribosomal protein L33
GHJEJHIM_00114 6e-51 moxR S ATPase family associated with various cellular activities (AAA)
GHJEJHIM_00115 9.6e-130 bla1 3.5.2.6 V Beta-lactamase enzyme family
GHJEJHIM_00116 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GHJEJHIM_00117 5e-145
GHJEJHIM_00118 5.8e-148 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
GHJEJHIM_00119 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
GHJEJHIM_00120 3.2e-38 fmdB S Putative regulatory protein
GHJEJHIM_00121 5.6e-110 flgA NO SAF
GHJEJHIM_00122 9.6e-42
GHJEJHIM_00123 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
GHJEJHIM_00124 4.2e-239 T Forkhead associated domain
GHJEJHIM_00126 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GHJEJHIM_00127 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GHJEJHIM_00128 6.8e-184 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
GHJEJHIM_00129 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
GHJEJHIM_00130 8.8e-222 pbuO S Permease family
GHJEJHIM_00131 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_00132 9.2e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_00133 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHJEJHIM_00134 5.3e-179 pstA P Phosphate transport system permease
GHJEJHIM_00135 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
GHJEJHIM_00136 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
GHJEJHIM_00137 1.3e-128 KT Transcriptional regulatory protein, C terminal
GHJEJHIM_00138 3.9e-243 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
GHJEJHIM_00139 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GHJEJHIM_00140 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHJEJHIM_00141 1.8e-107 K helix_turn_helix, Arsenical Resistance Operon Repressor
GHJEJHIM_00142 3.4e-242 EGP Major facilitator Superfamily
GHJEJHIM_00143 1.1e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GHJEJHIM_00144 9.9e-170 L Excalibur calcium-binding domain
GHJEJHIM_00145 9.3e-269 pepC 3.4.22.40 E Peptidase C1-like family
GHJEJHIM_00146 8.4e-45 D nuclear chromosome segregation
GHJEJHIM_00147 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GHJEJHIM_00148 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GHJEJHIM_00149 1.1e-189 yfiH Q Multi-copper polyphenol oxidoreductase laccase
GHJEJHIM_00150 0.0 yegQ O Peptidase family U32 C-terminal domain
GHJEJHIM_00151 8.7e-94 L Transposase and inactivated derivatives IS30 family
GHJEJHIM_00152 4.2e-95 L Transposase and inactivated derivatives IS30 family
GHJEJHIM_00153 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
GHJEJHIM_00154 2.2e-41 nrdH O Glutaredoxin
GHJEJHIM_00155 1.5e-98 nrdI F Probably involved in ribonucleotide reductase function
GHJEJHIM_00156 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHJEJHIM_00157 1.8e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHJEJHIM_00158 2.3e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GHJEJHIM_00159 0.0 S Predicted membrane protein (DUF2207)
GHJEJHIM_00160 3.7e-94 lemA S LemA family
GHJEJHIM_00161 7.2e-116 xylR K purine nucleotide biosynthetic process
GHJEJHIM_00162 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GHJEJHIM_00163 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GHJEJHIM_00164 4e-119
GHJEJHIM_00165 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
GHJEJHIM_00167 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
GHJEJHIM_00168 1.1e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GHJEJHIM_00169 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
GHJEJHIM_00170 7.2e-308 pccB I Carboxyl transferase domain
GHJEJHIM_00171 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
GHJEJHIM_00172 4.2e-93 bioY S BioY family
GHJEJHIM_00173 4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
GHJEJHIM_00174 0.0
GHJEJHIM_00175 5.9e-146 QT PucR C-terminal helix-turn-helix domain
GHJEJHIM_00176 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GHJEJHIM_00177 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GHJEJHIM_00178 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GHJEJHIM_00179 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHJEJHIM_00180 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GHJEJHIM_00181 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHJEJHIM_00182 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GHJEJHIM_00183 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHJEJHIM_00185 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
GHJEJHIM_00186 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GHJEJHIM_00188 4.6e-35
GHJEJHIM_00189 0.0 K RNA polymerase II activating transcription factor binding
GHJEJHIM_00190 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
GHJEJHIM_00191 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GHJEJHIM_00193 1.3e-102 mntP P Probably functions as a manganese efflux pump
GHJEJHIM_00194 1.4e-125
GHJEJHIM_00195 2e-135 KT Transcriptional regulatory protein, C terminal
GHJEJHIM_00196 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHJEJHIM_00197 1.3e-293 E Bacterial extracellular solute-binding proteins, family 5 Middle
GHJEJHIM_00198 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GHJEJHIM_00199 0.0 S domain protein
GHJEJHIM_00200 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
GHJEJHIM_00201 1.5e-89 lrp_3 K helix_turn_helix ASNC type
GHJEJHIM_00202 4.7e-235 E Aminotransferase class I and II
GHJEJHIM_00203 4.7e-304 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GHJEJHIM_00204 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
GHJEJHIM_00205 2.5e-52 S Protein of unknown function (DUF2469)
GHJEJHIM_00206 1.1e-197 2.3.1.57 J Acetyltransferase (GNAT) domain
GHJEJHIM_00207 3.2e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHJEJHIM_00208 2.4e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GHJEJHIM_00209 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHJEJHIM_00210 3.7e-82 V ABC transporter
GHJEJHIM_00211 1e-60 V ABC transporter
GHJEJHIM_00212 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
GHJEJHIM_00213 1.6e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHJEJHIM_00214 1.3e-214 rmuC S RmuC family
GHJEJHIM_00215 9.6e-43 csoR S Metal-sensitive transcriptional repressor
GHJEJHIM_00216 0.0 pacS 3.6.3.54 P E1-E2 ATPase
GHJEJHIM_00217 0.0 ubiB S ABC1 family
GHJEJHIM_00218 3.5e-19 S granule-associated protein
GHJEJHIM_00219 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
GHJEJHIM_00220 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
GHJEJHIM_00221 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GHJEJHIM_00222 8.2e-252 dinF V MatE
GHJEJHIM_00223 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
GHJEJHIM_00224 1e-54 glnB K Nitrogen regulatory protein P-II
GHJEJHIM_00225 1.3e-219 amt U Ammonium Transporter Family
GHJEJHIM_00226 5.6e-204 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHJEJHIM_00228 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
GHJEJHIM_00229 1e-195 XK27_01805 M Glycosyltransferase like family 2
GHJEJHIM_00230 0.0 S Glycosyl hydrolases related to GH101 family, GH129
GHJEJHIM_00231 1.4e-305 pepD E Peptidase family C69
GHJEJHIM_00232 5e-11 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
GHJEJHIM_00233 2.9e-19 XK26_04485 P Cobalt transport protein
GHJEJHIM_00234 4.8e-67 XK26_04485 P Cobalt transport protein
GHJEJHIM_00235 1.3e-81
GHJEJHIM_00236 0.0 V ABC transporter transmembrane region
GHJEJHIM_00237 1.8e-301 V ABC transporter, ATP-binding protein
GHJEJHIM_00238 1.3e-81 K Winged helix DNA-binding domain
GHJEJHIM_00239 3e-73 E IrrE N-terminal-like domain
GHJEJHIM_00241 1.1e-158 S Sucrose-6F-phosphate phosphohydrolase
GHJEJHIM_00242 3.5e-241 S Putative ABC-transporter type IV
GHJEJHIM_00243 7e-81
GHJEJHIM_00244 8.9e-34 Q phosphatase activity
GHJEJHIM_00245 6.8e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
GHJEJHIM_00246 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
GHJEJHIM_00247 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GHJEJHIM_00248 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHJEJHIM_00249 4.6e-67 S haloacid dehalogenase-like hydrolase
GHJEJHIM_00250 3.6e-131 yydK K UTRA
GHJEJHIM_00251 1.3e-70 S FMN_bind
GHJEJHIM_00252 5.7e-149 macB V ABC transporter, ATP-binding protein
GHJEJHIM_00253 2.9e-200 Z012_06715 V FtsX-like permease family
GHJEJHIM_00254 9.7e-223 macB_2 V ABC transporter permease
GHJEJHIM_00255 5.6e-231 S Predicted membrane protein (DUF2318)
GHJEJHIM_00256 1.8e-106 tpd P Fe2+ transport protein
GHJEJHIM_00257 1.5e-306 efeU_1 P Iron permease FTR1 family
GHJEJHIM_00258 6.9e-23 G MFS/sugar transport protein
GHJEJHIM_00259 1.7e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHJEJHIM_00260 1.7e-78 S Fic/DOC family
GHJEJHIM_00261 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHJEJHIM_00262 5e-38 ptsH G PTS HPr component phosphorylation site
GHJEJHIM_00263 4.4e-200 K helix_turn _helix lactose operon repressor
GHJEJHIM_00264 1.4e-212 holB 2.7.7.7 L DNA polymerase III
GHJEJHIM_00265 8.1e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHJEJHIM_00266 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHJEJHIM_00267 3.9e-188 3.6.1.27 I PAP2 superfamily
GHJEJHIM_00268 0.0 vpr M PA domain
GHJEJHIM_00269 3.2e-124 yplQ S Haemolysin-III related
GHJEJHIM_00270 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
GHJEJHIM_00271 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
GHJEJHIM_00272 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GHJEJHIM_00273 2.7e-279 S Calcineurin-like phosphoesterase
GHJEJHIM_00274 3.5e-20 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
GHJEJHIM_00275 2.7e-274 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
GHJEJHIM_00276 1.7e-116
GHJEJHIM_00277 2.2e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHJEJHIM_00279 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
GHJEJHIM_00280 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
GHJEJHIM_00281 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GHJEJHIM_00282 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
GHJEJHIM_00283 2.2e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
GHJEJHIM_00284 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
GHJEJHIM_00285 1.9e-41 S Protein of unknown function (DUF4244)
GHJEJHIM_00286 1.7e-28 gspF NU Type II secretion system (T2SS), protein F
GHJEJHIM_00287 3.1e-17 gspF NU Type II secretion system (T2SS), protein F
GHJEJHIM_00288 5.7e-121 U Type ii secretion system
GHJEJHIM_00289 3.4e-191 cpaF U Type II IV secretion system protein
GHJEJHIM_00290 2.6e-152 cpaE D bacterial-type flagellum organization
GHJEJHIM_00292 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GHJEJHIM_00293 5.3e-200 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
GHJEJHIM_00294 1.3e-91
GHJEJHIM_00295 4.2e-53 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GHJEJHIM_00296 5e-209 S Glycosyltransferase, group 2 family protein
GHJEJHIM_00297 3.4e-261
GHJEJHIM_00298 3.3e-26 thiS 2.8.1.10 H ThiS family
GHJEJHIM_00299 7e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GHJEJHIM_00300 0.0 S Psort location Cytoplasmic, score 8.87
GHJEJHIM_00301 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
GHJEJHIM_00302 4e-246 V ABC transporter permease
GHJEJHIM_00303 1e-179 V ABC transporter
GHJEJHIM_00304 5.4e-138 T HD domain
GHJEJHIM_00305 3e-164 S Glutamine amidotransferase domain
GHJEJHIM_00307 0.0 kup P Transport of potassium into the cell
GHJEJHIM_00308 5.9e-185 tatD L TatD related DNase
GHJEJHIM_00309 8.3e-256 xylR 5.3.1.12 G MFS/sugar transport protein
GHJEJHIM_00311 3.4e-86 K Transcriptional regulator
GHJEJHIM_00312 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHJEJHIM_00313 3.6e-130
GHJEJHIM_00314 8.6e-59
GHJEJHIM_00315 3.4e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHJEJHIM_00316 1e-125 dedA S SNARE associated Golgi protein
GHJEJHIM_00318 5.6e-139 S HAD hydrolase, family IA, variant 3
GHJEJHIM_00319 4e-173 terC P Integral membrane protein, TerC family
GHJEJHIM_00320 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GHJEJHIM_00321 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GHJEJHIM_00322 3.3e-243 rpsA J Ribosomal protein S1
GHJEJHIM_00323 6.9e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHJEJHIM_00324 2.1e-172 P Zinc-uptake complex component A periplasmic
GHJEJHIM_00325 5.3e-164 znuC P ATPases associated with a variety of cellular activities
GHJEJHIM_00326 7.3e-139 znuB U ABC 3 transport family
GHJEJHIM_00327 1.9e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GHJEJHIM_00328 5.1e-102 carD K CarD-like/TRCF domain
GHJEJHIM_00329 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GHJEJHIM_00330 1.9e-127 T Response regulator receiver domain protein
GHJEJHIM_00331 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GHJEJHIM_00332 8.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
GHJEJHIM_00333 1.3e-131 ctsW S Phosphoribosyl transferase domain
GHJEJHIM_00334 3.8e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
GHJEJHIM_00335 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
GHJEJHIM_00336 1.2e-264
GHJEJHIM_00337 0.0 S Glycosyl transferase, family 2
GHJEJHIM_00338 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
GHJEJHIM_00339 2.4e-270 K Cell envelope-related transcriptional attenuator domain
GHJEJHIM_00340 0.0 D FtsK/SpoIIIE family
GHJEJHIM_00341 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
GHJEJHIM_00342 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GHJEJHIM_00343 2e-142 yplQ S Haemolysin-III related
GHJEJHIM_00344 1.6e-108
GHJEJHIM_00346 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHJEJHIM_00347 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
GHJEJHIM_00348 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
GHJEJHIM_00349 4e-96
GHJEJHIM_00351 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
GHJEJHIM_00352 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
GHJEJHIM_00353 3.2e-101 divIC D Septum formation initiator
GHJEJHIM_00354 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHJEJHIM_00355 1.4e-152 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
GHJEJHIM_00356 5.2e-276 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
GHJEJHIM_00357 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHJEJHIM_00358 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GHJEJHIM_00359 2.7e-97 2.3.1.183 M Acetyltransferase (GNAT) domain
GHJEJHIM_00360 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
GHJEJHIM_00361 3.6e-151 GM ABC-2 type transporter
GHJEJHIM_00362 2.1e-196 GM GDP-mannose 4,6 dehydratase
GHJEJHIM_00363 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GHJEJHIM_00366 7e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
GHJEJHIM_00367 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GHJEJHIM_00368 2.3e-212 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GHJEJHIM_00369 0.0 S Uncharacterised protein family (UPF0182)
GHJEJHIM_00370 1.1e-213 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
GHJEJHIM_00371 4.2e-195
GHJEJHIM_00372 6.9e-150 ytrE V ATPases associated with a variety of cellular activities
GHJEJHIM_00373 3.1e-190 V N-Acetylmuramoyl-L-alanine amidase
GHJEJHIM_00374 5.2e-259 argE E Peptidase dimerisation domain
GHJEJHIM_00375 1.2e-103 S Protein of unknown function (DUF3043)
GHJEJHIM_00376 2.4e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GHJEJHIM_00377 2.3e-142 S Domain of unknown function (DUF4191)
GHJEJHIM_00378 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
GHJEJHIM_00379 4.7e-10
GHJEJHIM_00381 5.5e-33 traSA D DNA segregation ATPase FtsK SpoIIIE
GHJEJHIM_00385 5.2e-79 S GIY-YIG catalytic domain
GHJEJHIM_00386 7.8e-33 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
GHJEJHIM_00387 6.3e-115 L DNA restriction-modification system
GHJEJHIM_00388 2e-86 int L Phage integrase, N-terminal SAM-like domain
GHJEJHIM_00389 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_00390 1.5e-208 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GHJEJHIM_00391 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GHJEJHIM_00392 0.0 S Tetratricopeptide repeat
GHJEJHIM_00393 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GHJEJHIM_00394 4.9e-69 2.8.2.22 S Arylsulfotransferase Ig-like domain
GHJEJHIM_00395 1.3e-137 bioM P ATPases associated with a variety of cellular activities
GHJEJHIM_00396 2e-213 E Aminotransferase class I and II
GHJEJHIM_00397 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
GHJEJHIM_00399 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GHJEJHIM_00400 0.0 ecfA GP ABC transporter, ATP-binding protein
GHJEJHIM_00401 5.7e-256 EGP Major facilitator Superfamily
GHJEJHIM_00403 2.2e-257 rarA L Recombination factor protein RarA
GHJEJHIM_00404 0.0 L DEAD DEAH box helicase
GHJEJHIM_00405 3.9e-193 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
GHJEJHIM_00406 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00407 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00408 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
GHJEJHIM_00409 1.4e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
GHJEJHIM_00410 6.9e-86 S Aminoacyl-tRNA editing domain
GHJEJHIM_00411 3.3e-81 K helix_turn_helix, Lux Regulon
GHJEJHIM_00412 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GHJEJHIM_00413 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
GHJEJHIM_00414 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
GHJEJHIM_00418 0.0 clpC O ATPase family associated with various cellular activities (AAA)
GHJEJHIM_00419 4.7e-185 uspA T Belongs to the universal stress protein A family
GHJEJHIM_00420 8.3e-204 S Protein of unknown function (DUF3027)
GHJEJHIM_00421 1e-66 cspB K 'Cold-shock' DNA-binding domain
GHJEJHIM_00422 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GHJEJHIM_00423 1.6e-134 KT Response regulator receiver domain protein
GHJEJHIM_00424 4.9e-162
GHJEJHIM_00425 1.7e-10 S Proteins of 100 residues with WXG
GHJEJHIM_00426 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GHJEJHIM_00427 8.3e-44 cspA K 'Cold-shock' DNA-binding domain
GHJEJHIM_00428 7.6e-71 S LytR cell envelope-related transcriptional attenuator
GHJEJHIM_00429 8e-145 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GHJEJHIM_00430 2.3e-196 moxR S ATPase family associated with various cellular activities (AAA)
GHJEJHIM_00431 7.2e-178 S Protein of unknown function DUF58
GHJEJHIM_00432 6.4e-94
GHJEJHIM_00433 4.4e-189 S von Willebrand factor (vWF) type A domain
GHJEJHIM_00434 1.4e-147 S von Willebrand factor (vWF) type A domain
GHJEJHIM_00435 2.7e-74
GHJEJHIM_00437 2.9e-290 S PGAP1-like protein
GHJEJHIM_00438 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
GHJEJHIM_00439 0.0 S Lysylphosphatidylglycerol synthase TM region
GHJEJHIM_00440 8.1e-42 hup L Belongs to the bacterial histone-like protein family
GHJEJHIM_00441 2.2e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GHJEJHIM_00442 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
GHJEJHIM_00443 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
GHJEJHIM_00444 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
GHJEJHIM_00445 0.0 arc O AAA ATPase forming ring-shaped complexes
GHJEJHIM_00447 4.3e-138 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
GHJEJHIM_00448 5.6e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GHJEJHIM_00449 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GHJEJHIM_00450 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHJEJHIM_00451 9.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GHJEJHIM_00452 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GHJEJHIM_00453 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
GHJEJHIM_00454 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_00456 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GHJEJHIM_00457 0.0 ctpE P E1-E2 ATPase
GHJEJHIM_00458 2e-109
GHJEJHIM_00459 2.9e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHJEJHIM_00460 6.1e-124 S Protein of unknown function (DUF3159)
GHJEJHIM_00461 3.2e-139 S Protein of unknown function (DUF3710)
GHJEJHIM_00462 3.7e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
GHJEJHIM_00463 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
GHJEJHIM_00464 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
GHJEJHIM_00465 0.0 oppD P Belongs to the ABC transporter superfamily
GHJEJHIM_00466 4.6e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
GHJEJHIM_00467 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00468 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
GHJEJHIM_00469 7.3e-42
GHJEJHIM_00470 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
GHJEJHIM_00471 4.7e-196 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
GHJEJHIM_00472 1.7e-80
GHJEJHIM_00473 0.0 typA T Elongation factor G C-terminus
GHJEJHIM_00474 9.2e-234 iscS1 2.8.1.7 E Aminotransferase class-V
GHJEJHIM_00475 2.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
GHJEJHIM_00476 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
GHJEJHIM_00477 7.5e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GHJEJHIM_00478 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
GHJEJHIM_00479 2.1e-97 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GHJEJHIM_00480 3.6e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GHJEJHIM_00481 3.1e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
GHJEJHIM_00482 1.9e-178 xerD D recombinase XerD
GHJEJHIM_00483 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GHJEJHIM_00484 2.1e-25 rpmI J Ribosomal protein L35
GHJEJHIM_00485 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GHJEJHIM_00486 7.1e-68 S Spermine/spermidine synthase domain
GHJEJHIM_00487 2.1e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
GHJEJHIM_00488 8.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GHJEJHIM_00489 2.2e-93 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHJEJHIM_00491 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GHJEJHIM_00492 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
GHJEJHIM_00493 2e-64
GHJEJHIM_00494 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
GHJEJHIM_00495 5.3e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHJEJHIM_00496 9.8e-191 V Acetyltransferase (GNAT) domain
GHJEJHIM_00497 1.7e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
GHJEJHIM_00498 4e-242 yxbA 6.3.1.12 S ATP-grasp
GHJEJHIM_00499 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
GHJEJHIM_00500 0.0 smc D Required for chromosome condensation and partitioning
GHJEJHIM_00501 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
GHJEJHIM_00503 4.3e-97 3.6.1.55 F NUDIX domain
GHJEJHIM_00504 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
GHJEJHIM_00505 0.0 P Belongs to the ABC transporter superfamily
GHJEJHIM_00506 8.7e-191 dppC EP Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00507 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00508 2e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
GHJEJHIM_00509 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
GHJEJHIM_00510 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GHJEJHIM_00511 7e-217 GK ROK family
GHJEJHIM_00512 6.4e-131 cutC P Participates in the control of copper homeostasis
GHJEJHIM_00513 1.3e-224 GK ROK family
GHJEJHIM_00514 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
GHJEJHIM_00515 4.4e-236 G Major Facilitator Superfamily
GHJEJHIM_00516 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GHJEJHIM_00518 1.3e-37
GHJEJHIM_00519 8.1e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
GHJEJHIM_00520 2e-294 murC 6.3.2.8 M Belongs to the MurCDEF family
GHJEJHIM_00521 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GHJEJHIM_00522 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
GHJEJHIM_00523 1e-265 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GHJEJHIM_00524 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHJEJHIM_00525 1.1e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GHJEJHIM_00526 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHJEJHIM_00527 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
GHJEJHIM_00528 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GHJEJHIM_00529 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GHJEJHIM_00530 1.3e-90 mraZ K Belongs to the MraZ family
GHJEJHIM_00531 0.0 L DNA helicase
GHJEJHIM_00532 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
GHJEJHIM_00533 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GHJEJHIM_00534 6.1e-45 M Lysin motif
GHJEJHIM_00535 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHJEJHIM_00536 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GHJEJHIM_00537 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
GHJEJHIM_00538 2e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHJEJHIM_00539 3.9e-173
GHJEJHIM_00540 8.3e-122 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
GHJEJHIM_00541 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
GHJEJHIM_00542 2.6e-178 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GHJEJHIM_00543 4.1e-57 EGP Major facilitator Superfamily
GHJEJHIM_00544 9.4e-253 S Domain of unknown function (DUF5067)
GHJEJHIM_00545 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
GHJEJHIM_00546 1.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
GHJEJHIM_00547 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
GHJEJHIM_00548 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GHJEJHIM_00549 7.2e-111
GHJEJHIM_00550 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
GHJEJHIM_00551 2.3e-223 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GHJEJHIM_00552 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GHJEJHIM_00553 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_00554 4.6e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
GHJEJHIM_00556 3.4e-76 yneG S Domain of unknown function (DUF4186)
GHJEJHIM_00557 5.8e-174 dkgA 1.1.1.346 C Aldo/keto reductase family
GHJEJHIM_00558 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
GHJEJHIM_00559 3.4e-202 K WYL domain
GHJEJHIM_00561 0.0 4.2.1.53 S MCRA family
GHJEJHIM_00562 1.6e-46 yhbY J CRS1_YhbY
GHJEJHIM_00563 7.6e-106 S zinc-ribbon domain
GHJEJHIM_00564 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
GHJEJHIM_00565 5e-36 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
GHJEJHIM_00566 1.7e-18 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
GHJEJHIM_00567 1.6e-190 ywqG S Domain of unknown function (DUF1963)
GHJEJHIM_00568 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHJEJHIM_00569 5.1e-142 recO L Involved in DNA repair and RecF pathway recombination
GHJEJHIM_00570 2.7e-291 I acetylesterase activity
GHJEJHIM_00571 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GHJEJHIM_00572 1.2e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GHJEJHIM_00573 9e-199 2.7.11.1 NU Tfp pilus assembly protein FimV
GHJEJHIM_00575 1.6e-44
GHJEJHIM_00576 9.1e-46
GHJEJHIM_00577 1.7e-147 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
GHJEJHIM_00578 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GHJEJHIM_00579 4.8e-162 usp 3.5.1.28 CBM50 D CHAP domain protein
GHJEJHIM_00580 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
GHJEJHIM_00581 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
GHJEJHIM_00582 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHJEJHIM_00583 9.8e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
GHJEJHIM_00584 6e-63
GHJEJHIM_00586 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GHJEJHIM_00587 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GHJEJHIM_00588 9.7e-90 3.1.21.3 V DivIVA protein
GHJEJHIM_00589 2.1e-42 yggT S YGGT family
GHJEJHIM_00590 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GHJEJHIM_00591 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHJEJHIM_00592 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHJEJHIM_00593 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
GHJEJHIM_00594 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
GHJEJHIM_00595 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GHJEJHIM_00596 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GHJEJHIM_00597 1.3e-84
GHJEJHIM_00598 6.9e-231 O AAA domain (Cdc48 subfamily)
GHJEJHIM_00599 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GHJEJHIM_00600 4e-60 S Thiamine-binding protein
GHJEJHIM_00601 1.1e-195 K helix_turn _helix lactose operon repressor
GHJEJHIM_00602 5.7e-47 S Protein of unknown function (DUF3052)
GHJEJHIM_00603 1.1e-150 lon T Belongs to the peptidase S16 family
GHJEJHIM_00604 5.8e-283 S Zincin-like metallopeptidase
GHJEJHIM_00605 4.5e-280 uvrD2 3.6.4.12 L DNA helicase
GHJEJHIM_00606 2.1e-245 mphA S Aminoglycoside phosphotransferase
GHJEJHIM_00607 6.1e-32 S Protein of unknown function (DUF3107)
GHJEJHIM_00608 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
GHJEJHIM_00609 4.4e-115 S Vitamin K epoxide reductase
GHJEJHIM_00610 8.6e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
GHJEJHIM_00611 3.9e-153 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GHJEJHIM_00612 1.8e-168 S Patatin-like phospholipase
GHJEJHIM_00613 3.5e-191 V ABC transporter transmembrane region
GHJEJHIM_00614 7e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHJEJHIM_00615 3.7e-154 sapF E ATPases associated with a variety of cellular activities
GHJEJHIM_00616 2.6e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
GHJEJHIM_00617 5.8e-164 EP Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00618 1.4e-170 P Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00619 1.8e-309 E ABC transporter, substrate-binding protein, family 5
GHJEJHIM_00620 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GHJEJHIM_00621 4.4e-277 G Bacterial extracellular solute-binding protein
GHJEJHIM_00622 2.5e-62 G carbohydrate transport
GHJEJHIM_00623 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GHJEJHIM_00624 2e-126 G ABC transporter permease
GHJEJHIM_00625 2.9e-190 K Periplasmic binding protein domain
GHJEJHIM_00626 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
GHJEJHIM_00627 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
GHJEJHIM_00628 1.1e-17 L Helix-turn-helix domain
GHJEJHIM_00629 2.8e-17 S Protein of unknown function (DUF2442)
GHJEJHIM_00630 2.6e-16 K Helix-turn-helix domain
GHJEJHIM_00631 1e-52 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GHJEJHIM_00632 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GHJEJHIM_00633 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GHJEJHIM_00634 2.7e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
GHJEJHIM_00635 1.8e-127 XK27_08050 O prohibitin homologues
GHJEJHIM_00636 1.2e-241 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
GHJEJHIM_00637 4.4e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GHJEJHIM_00638 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
GHJEJHIM_00639 8.4e-224 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GHJEJHIM_00640 0.0 macB_2 V ATPases associated with a variety of cellular activities
GHJEJHIM_00641 0.0 ctpE P E1-E2 ATPase
GHJEJHIM_00642 1.1e-89 K acetyltransferase
GHJEJHIM_00643 1.2e-196 yghZ C Aldo/keto reductase family
GHJEJHIM_00644 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
GHJEJHIM_00645 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
GHJEJHIM_00646 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
GHJEJHIM_00647 5e-125 S Short repeat of unknown function (DUF308)
GHJEJHIM_00648 0.0 pepO 3.4.24.71 O Peptidase family M13
GHJEJHIM_00649 1.4e-103 L Single-strand binding protein family
GHJEJHIM_00650 3.2e-170
GHJEJHIM_00651 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GHJEJHIM_00654 2.5e-269 recD2 3.6.4.12 L PIF1-like helicase
GHJEJHIM_00655 1.1e-161 supH S Sucrose-6F-phosphate phosphohydrolase
GHJEJHIM_00656 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
GHJEJHIM_00657 3.1e-39 KT Transcriptional regulatory protein, C terminal
GHJEJHIM_00658 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
GHJEJHIM_00659 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GHJEJHIM_00660 1.8e-191 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
GHJEJHIM_00661 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
GHJEJHIM_00662 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
GHJEJHIM_00663 1.6e-185 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GHJEJHIM_00664 1.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHJEJHIM_00665 3.9e-36 rpmE J Binds the 23S rRNA
GHJEJHIM_00667 8.4e-193 K helix_turn_helix, arabinose operon control protein
GHJEJHIM_00668 9.4e-161 glcU G Sugar transport protein
GHJEJHIM_00669 5.7e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
GHJEJHIM_00670 3.5e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
GHJEJHIM_00671 2.8e-107
GHJEJHIM_00672 1.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
GHJEJHIM_00673 5.7e-139 3.5.2.6 V Beta-lactamase enzyme family
GHJEJHIM_00674 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
GHJEJHIM_00675 4.2e-164 EG EamA-like transporter family
GHJEJHIM_00677 1.1e-137 V FtsX-like permease family
GHJEJHIM_00678 4.4e-147 S Sulfite exporter TauE/SafE
GHJEJHIM_00680 1.5e-26 L Transposase
GHJEJHIM_00681 7.8e-213 MA20_36090 S Psort location Cytoplasmic, score 8.87
GHJEJHIM_00682 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
GHJEJHIM_00683 2.1e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
GHJEJHIM_00684 1.2e-72 EGP Major facilitator superfamily
GHJEJHIM_00685 5.2e-10 K Winged helix DNA-binding domain
GHJEJHIM_00686 3.7e-179 glkA 2.7.1.2 G ROK family
GHJEJHIM_00687 4.9e-301 S ATPases associated with a variety of cellular activities
GHJEJHIM_00688 1.2e-55 EGP Major facilitator Superfamily
GHJEJHIM_00689 2.4e-158 I alpha/beta hydrolase fold
GHJEJHIM_00690 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
GHJEJHIM_00692 5.1e-55 S DUF218 domain
GHJEJHIM_00693 9.6e-40 S Protein of unknown function (DUF979)
GHJEJHIM_00694 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GHJEJHIM_00695 5.7e-126
GHJEJHIM_00696 4.7e-48 M domain, Protein
GHJEJHIM_00697 4e-19 M domain, Protein
GHJEJHIM_00698 5.3e-306 yjjK S ATP-binding cassette protein, ChvD family
GHJEJHIM_00699 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
GHJEJHIM_00700 7.1e-172 tesB I Thioesterase-like superfamily
GHJEJHIM_00701 1.8e-74 S Protein of unknown function (DUF3180)
GHJEJHIM_00702 1.1e-291 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GHJEJHIM_00703 2.4e-161 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GHJEJHIM_00704 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
GHJEJHIM_00705 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHJEJHIM_00706 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHJEJHIM_00707 1.9e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GHJEJHIM_00708 3.8e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
GHJEJHIM_00709 2.1e-307
GHJEJHIM_00710 1.7e-168 natA V ATPases associated with a variety of cellular activities
GHJEJHIM_00711 1.3e-232 epsG M Glycosyl transferase family 21
GHJEJHIM_00712 4.3e-273 S AI-2E family transporter
GHJEJHIM_00713 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
GHJEJHIM_00714 3.1e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
GHJEJHIM_00717 3.7e-67 S Domain of unknown function (DUF4190)
GHJEJHIM_00718 2.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GHJEJHIM_00719 5.3e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GHJEJHIM_00721 4.1e-10
GHJEJHIM_00722 2.7e-18 S Transcription factor WhiB
GHJEJHIM_00723 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
GHJEJHIM_00724 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GHJEJHIM_00725 6e-180 lacR K Transcriptional regulator, LacI family
GHJEJHIM_00726 1e-224 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GHJEJHIM_00727 3.9e-119 K Transcriptional regulatory protein, C terminal
GHJEJHIM_00729 4.9e-95
GHJEJHIM_00730 2.2e-180 V N-Acetylmuramoyl-L-alanine amidase
GHJEJHIM_00731 2.8e-108 ytrE V ABC transporter
GHJEJHIM_00732 1.5e-171
GHJEJHIM_00733 9.9e-109
GHJEJHIM_00734 2.2e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
GHJEJHIM_00735 1.2e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GHJEJHIM_00736 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GHJEJHIM_00737 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GHJEJHIM_00738 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GHJEJHIM_00739 7.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
GHJEJHIM_00740 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHJEJHIM_00741 5.6e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
GHJEJHIM_00742 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHJEJHIM_00743 1.1e-158 K Helix-turn-helix domain, rpiR family
GHJEJHIM_00744 4.6e-227 K Putative ATP-dependent DNA helicase recG C-terminal
GHJEJHIM_00745 2.3e-43 S Memo-like protein
GHJEJHIM_00747 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GHJEJHIM_00748 3.2e-178 adh3 C Zinc-binding dehydrogenase
GHJEJHIM_00749 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GHJEJHIM_00750 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GHJEJHIM_00751 4.3e-73 zur P Belongs to the Fur family
GHJEJHIM_00752 2.9e-44
GHJEJHIM_00753 2.6e-154 S TIGRFAM TIGR03943 family protein
GHJEJHIM_00754 1.6e-202 ycgR S Predicted permease
GHJEJHIM_00755 2.3e-23 J Ribosomal L32p protein family
GHJEJHIM_00756 8.2e-15 rpmJ J Ribosomal protein L36
GHJEJHIM_00757 2e-42 rpmE2 J Ribosomal protein L31
GHJEJHIM_00758 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHJEJHIM_00759 5.5e-48 rpmB J Ribosomal L28 family
GHJEJHIM_00760 1e-128 S cobalamin synthesis protein
GHJEJHIM_00761 2.1e-160 P Zinc-uptake complex component A periplasmic
GHJEJHIM_00763 0.0 lysX S Uncharacterised conserved protein (DUF2156)
GHJEJHIM_00764 1.3e-246 S Putative esterase
GHJEJHIM_00765 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
GHJEJHIM_00766 9.4e-239 purD 6.3.4.13 F Belongs to the GARS family
GHJEJHIM_00767 2.6e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GHJEJHIM_00768 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GHJEJHIM_00769 2.8e-301 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
GHJEJHIM_00770 2e-32
GHJEJHIM_00771 3e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GHJEJHIM_00772 1.8e-20 K DNA-binding transcription factor activity
GHJEJHIM_00773 2.2e-114 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
GHJEJHIM_00774 4.5e-96 S Protein of unknown function (DUF4230)
GHJEJHIM_00775 2.9e-106
GHJEJHIM_00776 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
GHJEJHIM_00777 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GHJEJHIM_00778 2.3e-232 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GHJEJHIM_00779 0.0 M Parallel beta-helix repeats
GHJEJHIM_00780 1.2e-227 M Glycosyl transferase 4-like domain
GHJEJHIM_00781 1.7e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
GHJEJHIM_00783 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GHJEJHIM_00784 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GHJEJHIM_00785 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GHJEJHIM_00786 6.8e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GHJEJHIM_00787 0.0 S Esterase-like activity of phytase
GHJEJHIM_00788 1e-191 EGP Transmembrane secretion effector
GHJEJHIM_00790 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHJEJHIM_00791 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GHJEJHIM_00792 1e-237 carA 6.3.5.5 F Belongs to the CarA family
GHJEJHIM_00793 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
GHJEJHIM_00794 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
GHJEJHIM_00795 0.0 S Protein of unknown function DUF262
GHJEJHIM_00796 4.1e-116 K helix_turn_helix, Lux Regulon
GHJEJHIM_00797 2.9e-268 T Histidine kinase
GHJEJHIM_00798 1e-97 S Domain of unknown function (DUF5067)
GHJEJHIM_00799 1.5e-131 ybhL S Belongs to the BI1 family
GHJEJHIM_00800 1.1e-167 ydeD EG EamA-like transporter family
GHJEJHIM_00801 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
GHJEJHIM_00802 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GHJEJHIM_00803 9e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GHJEJHIM_00804 1.3e-136 fic D Fic/DOC family
GHJEJHIM_00805 0.0 ftsK D FtsK SpoIIIE family protein
GHJEJHIM_00806 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHJEJHIM_00807 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
GHJEJHIM_00808 1.6e-80 K Helix-turn-helix XRE-family like proteins
GHJEJHIM_00809 3.7e-40 S Protein of unknown function (DUF3046)
GHJEJHIM_00810 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GHJEJHIM_00811 7.1e-74 recX S Modulates RecA activity
GHJEJHIM_00812 1e-07
GHJEJHIM_00814 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHJEJHIM_00815 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHJEJHIM_00816 6.7e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GHJEJHIM_00817 1.5e-109
GHJEJHIM_00818 4.6e-134 plsC2 2.3.1.51 I Phosphate acyltransferases
GHJEJHIM_00819 0.0 pknL 2.7.11.1 KLT PASTA
GHJEJHIM_00820 2.3e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
GHJEJHIM_00821 1.3e-122
GHJEJHIM_00822 4.1e-180 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHJEJHIM_00823 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
GHJEJHIM_00824 5.2e-278 aspA 4.3.1.1 E Fumarase C C-terminus
GHJEJHIM_00825 5.2e-45 S Protein of unknown function (DUF2975)
GHJEJHIM_00826 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
GHJEJHIM_00827 0.0 lhr L DEAD DEAH box helicase
GHJEJHIM_00828 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
GHJEJHIM_00829 9.5e-236 S Type I phosphodiesterase / nucleotide pyrophosphatase
GHJEJHIM_00830 1.6e-186 S Protein of unknown function (DUF3071)
GHJEJHIM_00831 1.4e-47 S Domain of unknown function (DUF4193)
GHJEJHIM_00832 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GHJEJHIM_00833 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHJEJHIM_00834 6.9e-12
GHJEJHIM_00835 1.3e-207 E Belongs to the peptidase S1B family
GHJEJHIM_00836 8.8e-68 T Toxic component of a toxin-antitoxin (TA) module
GHJEJHIM_00837 1.1e-49 relB L RelB antitoxin
GHJEJHIM_00838 2.3e-07
GHJEJHIM_00840 6.2e-142 pgp 3.1.3.18 S HAD-hyrolase-like
GHJEJHIM_00841 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
GHJEJHIM_00842 0.0 helY L DEAD DEAH box helicase
GHJEJHIM_00843 1e-51
GHJEJHIM_00844 0.0 pafB K WYL domain
GHJEJHIM_00845 7.4e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
GHJEJHIM_00847 7.3e-89 dkgB S Oxidoreductase, aldo keto reductase family protein
GHJEJHIM_00848 1.4e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
GHJEJHIM_00849 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHJEJHIM_00850 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GHJEJHIM_00851 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
GHJEJHIM_00852 9.2e-89 T Domain of unknown function (DUF4234)
GHJEJHIM_00853 4.2e-101 K Bacterial regulatory proteins, tetR family
GHJEJHIM_00854 1.2e-18
GHJEJHIM_00855 2.6e-48 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
GHJEJHIM_00856 3.7e-41 K Helix-turn-helix
GHJEJHIM_00857 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
GHJEJHIM_00858 1.1e-67 4.1.1.44 S Cupin domain
GHJEJHIM_00859 1.8e-176 S Membrane transport protein
GHJEJHIM_00860 1.4e-92 laaE K Transcriptional regulator PadR-like family
GHJEJHIM_00861 3.9e-133 magIII L endonuclease III
GHJEJHIM_00862 9.6e-132 S Enoyl-(Acyl carrier protein) reductase
GHJEJHIM_00863 1.1e-242 vbsD V MatE
GHJEJHIM_00864 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GHJEJHIM_00865 1e-14 KLT Protein tyrosine kinase
GHJEJHIM_00866 1.3e-16 K Psort location Cytoplasmic, score
GHJEJHIM_00867 2.8e-141
GHJEJHIM_00868 5.4e-192 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
GHJEJHIM_00869 1.3e-16 K MerR family regulatory protein
GHJEJHIM_00870 2.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHJEJHIM_00871 2.8e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GHJEJHIM_00872 6.5e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
GHJEJHIM_00873 1.2e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
GHJEJHIM_00874 1.9e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHJEJHIM_00875 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
GHJEJHIM_00876 6.4e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GHJEJHIM_00877 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
GHJEJHIM_00879 2.9e-159 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
GHJEJHIM_00880 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GHJEJHIM_00881 2.6e-100 sixA T Phosphoglycerate mutase family
GHJEJHIM_00882 5.7e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GHJEJHIM_00883 8.8e-178 I alpha/beta hydrolase fold
GHJEJHIM_00884 1.4e-23 rarD S EamA-like transporter family
GHJEJHIM_00885 8.3e-81 rarD 3.4.17.13 E Rard protein
GHJEJHIM_00886 4.2e-29
GHJEJHIM_00887 2.7e-220 L Uncharacterized conserved protein (DUF2075)
GHJEJHIM_00888 1.6e-28
GHJEJHIM_00889 1.8e-138 L Transposase
GHJEJHIM_00890 1.4e-60 S Short C-terminal domain
GHJEJHIM_00891 3.2e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHJEJHIM_00892 3e-50 S Sel1-like repeats.
GHJEJHIM_00893 5.9e-158 ybeM S Carbon-nitrogen hydrolase
GHJEJHIM_00894 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
GHJEJHIM_00895 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
GHJEJHIM_00896 3.6e-82
GHJEJHIM_00897 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GHJEJHIM_00898 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
GHJEJHIM_00899 0.0 tetP J Elongation factor G, domain IV
GHJEJHIM_00900 4.5e-291 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
GHJEJHIM_00901 4e-13 S Membrane
GHJEJHIM_00902 3e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
GHJEJHIM_00903 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHJEJHIM_00904 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
GHJEJHIM_00905 1.2e-135 S UPF0126 domain
GHJEJHIM_00906 8.2e-116 3.1.4.37 T RNA ligase
GHJEJHIM_00907 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
GHJEJHIM_00908 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GHJEJHIM_00909 1.2e-188 S alpha beta
GHJEJHIM_00910 2.6e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GHJEJHIM_00911 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
GHJEJHIM_00912 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
GHJEJHIM_00913 0.0 fadD 6.2.1.3 I AMP-binding enzyme
GHJEJHIM_00914 3.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GHJEJHIM_00915 1.6e-250 corC S CBS domain
GHJEJHIM_00916 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHJEJHIM_00917 6.5e-196 phoH T PhoH-like protein
GHJEJHIM_00918 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
GHJEJHIM_00919 6.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GHJEJHIM_00921 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
GHJEJHIM_00922 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GHJEJHIM_00923 1.2e-108 yitW S Iron-sulfur cluster assembly protein
GHJEJHIM_00924 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
GHJEJHIM_00925 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHJEJHIM_00926 1.4e-144 sufC O FeS assembly ATPase SufC
GHJEJHIM_00927 5.7e-233 sufD O FeS assembly protein SufD
GHJEJHIM_00928 4.8e-290 sufB O FeS assembly protein SufB
GHJEJHIM_00929 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GHJEJHIM_00930 2.6e-07 3.4.22.70 M Sortase family
GHJEJHIM_00931 1.7e-120 K helix_turn_helix, Lux Regulon
GHJEJHIM_00932 3.4e-15
GHJEJHIM_00933 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
GHJEJHIM_00934 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GHJEJHIM_00935 3.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GHJEJHIM_00936 1.4e-46 3.4.23.43 S Type IV leader peptidase family
GHJEJHIM_00937 2.3e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GHJEJHIM_00938 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GHJEJHIM_00939 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GHJEJHIM_00940 1.1e-36
GHJEJHIM_00941 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
GHJEJHIM_00942 9.5e-135 pgm3 G Phosphoglycerate mutase family
GHJEJHIM_00943 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
GHJEJHIM_00944 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GHJEJHIM_00945 9e-126 lolD V ABC transporter
GHJEJHIM_00946 5.5e-212 V FtsX-like permease family
GHJEJHIM_00947 1.1e-63 S Domain of unknown function (DUF4418)
GHJEJHIM_00948 0.0 pcrA 3.6.4.12 L DNA helicase
GHJEJHIM_00949 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
GHJEJHIM_00950 8.7e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GHJEJHIM_00951 1.1e-240 pbuX F Permease family
GHJEJHIM_00953 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHJEJHIM_00954 8.3e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHJEJHIM_00956 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
GHJEJHIM_00957 9e-40
GHJEJHIM_00958 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
GHJEJHIM_00959 1.7e-181 tnp7109-21 L Integrase core domain
GHJEJHIM_00960 8.6e-48 L Transposase
GHJEJHIM_00961 1.2e-64 D MobA/MobL family
GHJEJHIM_00962 1.3e-78
GHJEJHIM_00964 2.7e-199 L Transposase and inactivated derivatives IS30 family
GHJEJHIM_00965 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GHJEJHIM_00966 1.4e-59 S Bacterial mobilisation protein (MobC)
GHJEJHIM_00967 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
GHJEJHIM_00968 4.7e-105
GHJEJHIM_00971 5.7e-259 L Phage integrase, N-terminal SAM-like domain
GHJEJHIM_00973 1.3e-16 M Belongs to the glycosyl hydrolase 30 family
GHJEJHIM_00974 6.3e-95 M Belongs to the glycosyl hydrolase 30 family
GHJEJHIM_00975 2.2e-190 1.1.1.65 C Aldo/keto reductase family
GHJEJHIM_00976 3.8e-93 ydgJ K helix_turn_helix multiple antibiotic resistance protein
GHJEJHIM_00977 0.0 lmrA1 V ABC transporter, ATP-binding protein
GHJEJHIM_00978 0.0 lmrA2 V ABC transporter transmembrane region
GHJEJHIM_00979 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
GHJEJHIM_00980 1.3e-107 S Phosphatidylethanolamine-binding protein
GHJEJHIM_00981 0.0 pepD E Peptidase family C69
GHJEJHIM_00982 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
GHJEJHIM_00983 1.3e-62 S Macrophage migration inhibitory factor (MIF)
GHJEJHIM_00984 6.8e-98 S GtrA-like protein
GHJEJHIM_00985 6.2e-263 EGP Major facilitator Superfamily
GHJEJHIM_00986 8.1e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
GHJEJHIM_00987 7.1e-143
GHJEJHIM_00988 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
GHJEJHIM_00989 3.3e-200 P NMT1/THI5 like
GHJEJHIM_00990 1.1e-124 S HAD hydrolase, family IA, variant 3
GHJEJHIM_00992 7.7e-296 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GHJEJHIM_00993 3.1e-95 S Domain of unknown function (DUF4143)
GHJEJHIM_00994 1.9e-65 S Domain of unknown function (DUF4143)
GHJEJHIM_00997 4.1e-250 S Calcineurin-like phosphoesterase
GHJEJHIM_00998 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
GHJEJHIM_00999 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GHJEJHIM_01000 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GHJEJHIM_01001 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
GHJEJHIM_01003 2.4e-190 S CAAX protease self-immunity
GHJEJHIM_01004 4e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
GHJEJHIM_01005 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHJEJHIM_01006 7.4e-226 G Transmembrane secretion effector
GHJEJHIM_01007 8.7e-133 K Bacterial regulatory proteins, tetR family
GHJEJHIM_01008 1e-125
GHJEJHIM_01009 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GHJEJHIM_01010 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GHJEJHIM_01011 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
GHJEJHIM_01012 5.4e-187
GHJEJHIM_01013 7.9e-180
GHJEJHIM_01014 1.3e-163 trxA2 O Tetratricopeptide repeat
GHJEJHIM_01015 2.8e-119 cyaA 4.6.1.1 S CYTH
GHJEJHIM_01017 4.1e-184 K Bacterial regulatory proteins, lacI family
GHJEJHIM_01018 3.9e-16 4.2.1.68 M carboxylic acid catabolic process
GHJEJHIM_01019 9.5e-41 4.2.1.68 M Enolase C-terminal domain-like
GHJEJHIM_01020 3.4e-163 IQ KR domain
GHJEJHIM_01022 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
GHJEJHIM_01023 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
GHJEJHIM_01024 2e-18 psp1 3.5.99.10 J Endoribonuclease L-PSP
GHJEJHIM_01025 2.2e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GHJEJHIM_01026 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GHJEJHIM_01027 2.8e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GHJEJHIM_01028 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GHJEJHIM_01029 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
GHJEJHIM_01030 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
GHJEJHIM_01031 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHJEJHIM_01032 9.9e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
GHJEJHIM_01033 1.4e-65
GHJEJHIM_01034 1.4e-57
GHJEJHIM_01035 1.6e-163 V ATPases associated with a variety of cellular activities
GHJEJHIM_01036 3.5e-253 V Efflux ABC transporter, permease protein
GHJEJHIM_01037 3.2e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
GHJEJHIM_01038 4.9e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
GHJEJHIM_01039 0.0 rne 3.1.26.12 J Ribonuclease E/G family
GHJEJHIM_01040 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
GHJEJHIM_01041 3.1e-40 rpmA J Ribosomal L27 protein
GHJEJHIM_01042 6.3e-215 K Psort location Cytoplasmic, score
GHJEJHIM_01043 1.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GHJEJHIM_01044 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GHJEJHIM_01045 7.6e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
GHJEJHIM_01047 1.2e-30 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GHJEJHIM_01048 3.5e-117 nusG K Participates in transcription elongation, termination and antitermination
GHJEJHIM_01049 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
GHJEJHIM_01050 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
GHJEJHIM_01051 2.8e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GHJEJHIM_01052 1.4e-200 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GHJEJHIM_01053 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
GHJEJHIM_01054 1.5e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHJEJHIM_01055 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHJEJHIM_01056 5.2e-114
GHJEJHIM_01057 1.7e-234 patB 4.4.1.8 E Aminotransferase, class I II
GHJEJHIM_01058 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GHJEJHIM_01059 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
GHJEJHIM_01060 4.4e-118 safC S O-methyltransferase
GHJEJHIM_01061 4.3e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
GHJEJHIM_01062 2.8e-69 yraN L Belongs to the UPF0102 family
GHJEJHIM_01063 1.2e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
GHJEJHIM_01064 5.7e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
GHJEJHIM_01065 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
GHJEJHIM_01066 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
GHJEJHIM_01067 7.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GHJEJHIM_01068 3.9e-156 S Putative ABC-transporter type IV
GHJEJHIM_01069 7.7e-252 metY 2.5.1.49 E Aminotransferase class-V
GHJEJHIM_01070 2.9e-102
GHJEJHIM_01071 2.8e-140
GHJEJHIM_01072 8.3e-34 tnp7109-21 L Integrase core domain
GHJEJHIM_01073 2.6e-161 V ABC transporter, ATP-binding protein
GHJEJHIM_01074 0.0 MV MacB-like periplasmic core domain
GHJEJHIM_01075 0.0 phoN I PAP2 superfamily
GHJEJHIM_01076 6.1e-132 K helix_turn_helix, Lux Regulon
GHJEJHIM_01077 0.0 tcsS2 T Histidine kinase
GHJEJHIM_01078 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
GHJEJHIM_01079 4.7e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GHJEJHIM_01080 2.4e-167 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
GHJEJHIM_01081 3.2e-147 P NLPA lipoprotein
GHJEJHIM_01082 9.4e-186 acoA 1.2.4.1 C Dehydrogenase E1 component
GHJEJHIM_01083 6.6e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
GHJEJHIM_01084 3e-204 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHJEJHIM_01085 1.1e-92 metI P Binding-protein-dependent transport system inner membrane component
GHJEJHIM_01086 4.4e-230 mtnE 2.6.1.83 E Aminotransferase class I and II
GHJEJHIM_01087 3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GHJEJHIM_01088 3.8e-133 int L Phage integrase, N-terminal SAM-like domain
GHJEJHIM_01089 1.1e-47 int L Phage integrase, N-terminal SAM-like domain
GHJEJHIM_01090 3.7e-10 S Protein of unknown function (DUF3800)
GHJEJHIM_01091 1e-07 S Protein of unknown function (DUF3800)
GHJEJHIM_01092 9.7e-30
GHJEJHIM_01093 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
GHJEJHIM_01094 2.6e-119 dprA LU DNA recombination-mediator protein A
GHJEJHIM_01095 8.2e-61 S competence protein
GHJEJHIM_01096 3.4e-09
GHJEJHIM_01099 4.6e-16
GHJEJHIM_01100 4.3e-114 L Integrase core domain
GHJEJHIM_01101 1.1e-36 L Psort location Cytoplasmic, score 8.87
GHJEJHIM_01102 3.9e-120 E Psort location Cytoplasmic, score 8.87
GHJEJHIM_01103 5.6e-59 yccF S Inner membrane component domain
GHJEJHIM_01104 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
GHJEJHIM_01105 1e-65 S Cupin 2, conserved barrel domain protein
GHJEJHIM_01106 4.1e-258 KLT Protein tyrosine kinase
GHJEJHIM_01107 4.5e-79 K Psort location Cytoplasmic, score
GHJEJHIM_01108 4.1e-149
GHJEJHIM_01109 2.7e-22
GHJEJHIM_01110 5.5e-199 S Short C-terminal domain
GHJEJHIM_01111 1e-86 S Helix-turn-helix
GHJEJHIM_01112 2.8e-66 S Zincin-like metallopeptidase
GHJEJHIM_01113 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GHJEJHIM_01114 2.6e-39
GHJEJHIM_01115 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GHJEJHIM_01116 6.1e-125 ypfH S Phospholipase/Carboxylesterase
GHJEJHIM_01117 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
GHJEJHIM_01120 1.2e-291 2.4.1.166 GT2 M Glycosyltransferase like family 2
GHJEJHIM_01121 6e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
GHJEJHIM_01122 7.3e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
GHJEJHIM_01123 3.5e-186 MA20_14895 S Conserved hypothetical protein 698
GHJEJHIM_01124 6.1e-57 estB S Phospholipase/Carboxylesterase
GHJEJHIM_01125 3.1e-158 3.1.3.73 G Phosphoglycerate mutase family
GHJEJHIM_01126 6.9e-237 rutG F Permease family
GHJEJHIM_01127 4.9e-91 K AraC-like ligand binding domain
GHJEJHIM_01129 6e-42 IQ oxidoreductase activity
GHJEJHIM_01130 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
GHJEJHIM_01131 2.9e-134 ybbL V ATPases associated with a variety of cellular activities
GHJEJHIM_01132 3.9e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHJEJHIM_01133 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GHJEJHIM_01134 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
GHJEJHIM_01135 1.3e-87
GHJEJHIM_01136 3.2e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GHJEJHIM_01137 1.3e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GHJEJHIM_01138 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GHJEJHIM_01139 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
GHJEJHIM_01140 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GHJEJHIM_01141 1.4e-84 argR K Regulates arginine biosynthesis genes
GHJEJHIM_01142 2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GHJEJHIM_01143 5.9e-59 3.1.21.3 V type I restriction modification DNA specificity domain
GHJEJHIM_01144 8.9e-58 3.6.4.12 K Putative DNA-binding domain
GHJEJHIM_01145 2.1e-183 K Putative DNA-binding domain
GHJEJHIM_01146 1.5e-45 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GHJEJHIM_01147 4e-181 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GHJEJHIM_01148 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
GHJEJHIM_01149 3.8e-110 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHJEJHIM_01150 1.6e-143 S Putative ABC-transporter type IV
GHJEJHIM_01151 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GHJEJHIM_01152 1.2e-88 V ATPases associated with a variety of cellular activities
GHJEJHIM_01153 2e-73 I Sterol carrier protein
GHJEJHIM_01154 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GHJEJHIM_01155 3.4e-35
GHJEJHIM_01156 6.4e-145 gluP 3.4.21.105 S Rhomboid family
GHJEJHIM_01157 9.8e-120 L HTH-like domain
GHJEJHIM_01158 4.7e-257 L ribosomal rna small subunit methyltransferase
GHJEJHIM_01159 6.9e-67 crgA D Involved in cell division
GHJEJHIM_01160 7.9e-143 S Bacterial protein of unknown function (DUF881)
GHJEJHIM_01161 2.2e-232 srtA 3.4.22.70 M Sortase family
GHJEJHIM_01162 1.9e-118 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
GHJEJHIM_01163 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
GHJEJHIM_01164 2e-183 T Protein tyrosine kinase
GHJEJHIM_01165 1.4e-262 pbpA M penicillin-binding protein
GHJEJHIM_01166 6.8e-265 rodA D Belongs to the SEDS family
GHJEJHIM_01167 7.3e-257 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
GHJEJHIM_01168 2.6e-92 fhaB T Inner membrane component of T3SS, cytoplasmic domain
GHJEJHIM_01169 1e-130 fhaA T Protein of unknown function (DUF2662)
GHJEJHIM_01170 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
GHJEJHIM_01171 0.0 pip S YhgE Pip domain protein
GHJEJHIM_01172 0.0 pip S YhgE Pip domain protein
GHJEJHIM_01173 3.9e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
GHJEJHIM_01174 9.5e-167 yicL EG EamA-like transporter family
GHJEJHIM_01175 9.6e-98
GHJEJHIM_01177 1.6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GHJEJHIM_01179 0.0 KL Domain of unknown function (DUF3427)
GHJEJHIM_01180 3.9e-37 KL Domain of unknown function (DUF3427)
GHJEJHIM_01181 1.8e-12 KL Domain of unknown function (DUF3427)
GHJEJHIM_01182 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
GHJEJHIM_01183 1.3e-37 D DivIVA domain protein
GHJEJHIM_01184 1.7e-51 ybjQ S Putative heavy-metal-binding
GHJEJHIM_01185 1.1e-155 I Serine aminopeptidase, S33
GHJEJHIM_01186 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
GHJEJHIM_01188 1.4e-258 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GHJEJHIM_01189 2.3e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
GHJEJHIM_01190 0.0 cadA P E1-E2 ATPase
GHJEJHIM_01191 3.6e-271 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
GHJEJHIM_01192 3.4e-169 htpX O Belongs to the peptidase M48B family
GHJEJHIM_01194 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
GHJEJHIM_01195 1.9e-42 S Bacterial mobilisation protein (MobC)
GHJEJHIM_01196 2.3e-127 S Domain of unknown function (DUF4417)
GHJEJHIM_01198 1.9e-61
GHJEJHIM_01199 6.8e-65
GHJEJHIM_01200 3.9e-50 E IrrE N-terminal-like domain
GHJEJHIM_01201 2e-12 E IrrE N-terminal-like domain
GHJEJHIM_01202 4.9e-57 K Cro/C1-type HTH DNA-binding domain
GHJEJHIM_01203 6.6e-248 3.5.1.104 G Polysaccharide deacetylase
GHJEJHIM_01204 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GHJEJHIM_01205 1.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GHJEJHIM_01206 5.1e-165 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHJEJHIM_01207 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHJEJHIM_01208 7.1e-200 K helix_turn _helix lactose operon repressor
GHJEJHIM_01209 2.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
GHJEJHIM_01210 7e-298 scrT G Transporter major facilitator family protein
GHJEJHIM_01211 2.9e-254 yhjE EGP Sugar (and other) transporter
GHJEJHIM_01212 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GHJEJHIM_01213 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GHJEJHIM_01214 9.7e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
GHJEJHIM_01215 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GHJEJHIM_01216 9.6e-275 aroP E aromatic amino acid transport protein AroP K03293
GHJEJHIM_01217 2.4e-101 K Transcriptional regulator C-terminal region
GHJEJHIM_01218 2.6e-129 V ABC transporter
GHJEJHIM_01219 0.0 V FtsX-like permease family
GHJEJHIM_01220 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHJEJHIM_01221 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GHJEJHIM_01222 1.2e-39 E ABC transporter
GHJEJHIM_01223 7.6e-100 bcp 1.11.1.15 O Redoxin
GHJEJHIM_01224 2.6e-148 S Virulence factor BrkB
GHJEJHIM_01225 2.1e-41 XAC3035 O Glutaredoxin
GHJEJHIM_01226 6.2e-105 L Transposase
GHJEJHIM_01227 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GHJEJHIM_01228 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GHJEJHIM_01229 5.5e-55 L HNH endonuclease
GHJEJHIM_01230 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
GHJEJHIM_01231 4.9e-117
GHJEJHIM_01236 1.6e-07 L DNA integration
GHJEJHIM_01237 7.1e-38 L Phage integrase family
GHJEJHIM_01239 6.7e-35 D FtsK/SpoIIIE family
GHJEJHIM_01241 3.4e-52 S Eco47II restriction endonuclease
GHJEJHIM_01242 8.6e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
GHJEJHIM_01243 1.3e-12 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
GHJEJHIM_01244 6.2e-235 K Helix-turn-helix XRE-family like proteins
GHJEJHIM_01245 3.8e-34 3.4.11.5 I carboxylic ester hydrolase activity
GHJEJHIM_01246 8.1e-54 relB L RelB antitoxin
GHJEJHIM_01247 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
GHJEJHIM_01248 1.7e-131 K helix_turn_helix, mercury resistance
GHJEJHIM_01249 1e-243 yxiO S Vacuole effluxer Atg22 like
GHJEJHIM_01251 6.5e-201 yegV G pfkB family carbohydrate kinase
GHJEJHIM_01252 1.4e-29 rpmB J Ribosomal L28 family
GHJEJHIM_01253 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
GHJEJHIM_01254 3.8e-219 steT E amino acid
GHJEJHIM_01257 3.2e-310
GHJEJHIM_01258 1.9e-247 U Sodium:dicarboxylate symporter family
GHJEJHIM_01259 6.4e-120 rsmD 2.1.1.171 L Conserved hypothetical protein 95
GHJEJHIM_01260 6.3e-108 XK27_02070 S Nitroreductase family
GHJEJHIM_01261 3.8e-81 hsp20 O Hsp20/alpha crystallin family
GHJEJHIM_01262 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GHJEJHIM_01263 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GHJEJHIM_01264 1.8e-34 CP_0960 S Belongs to the UPF0109 family
GHJEJHIM_01265 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GHJEJHIM_01266 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
GHJEJHIM_01267 2.9e-93 argO S LysE type translocator
GHJEJHIM_01268 9e-220 S Endonuclease/Exonuclease/phosphatase family
GHJEJHIM_01269 3.5e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHJEJHIM_01270 3.5e-163 P Cation efflux family
GHJEJHIM_01271 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHJEJHIM_01272 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
GHJEJHIM_01273 0.0 yjjK S ABC transporter
GHJEJHIM_01274 2e-58 S Protein of unknown function (DUF3039)
GHJEJHIM_01275 1.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GHJEJHIM_01276 3.6e-107
GHJEJHIM_01277 1e-113 yceD S Uncharacterized ACR, COG1399
GHJEJHIM_01278 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GHJEJHIM_01279 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHJEJHIM_01280 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
GHJEJHIM_01281 7.6e-92 ilvN 2.2.1.6 E ACT domain
GHJEJHIM_01283 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHJEJHIM_01284 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GHJEJHIM_01285 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GHJEJHIM_01286 2.4e-176 S Auxin Efflux Carrier
GHJEJHIM_01289 0.0 pgi 5.3.1.9 G Belongs to the GPI family
GHJEJHIM_01290 5.6e-190
GHJEJHIM_01292 6.9e-201
GHJEJHIM_01294 1.6e-121 mgtC S MgtC family
GHJEJHIM_01295 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
GHJEJHIM_01296 4.3e-275 abcT3 P ATPases associated with a variety of cellular activities
GHJEJHIM_01297 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
GHJEJHIM_01298 1.4e-173 K Putative sugar-binding domain
GHJEJHIM_01299 8.8e-213 gatC G PTS system sugar-specific permease component
GHJEJHIM_01300 1.5e-294 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
GHJEJHIM_01301 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
GHJEJHIM_01302 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
GHJEJHIM_01303 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GHJEJHIM_01304 7.6e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHJEJHIM_01305 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHJEJHIM_01306 3.9e-201 K helix_turn _helix lactose operon repressor
GHJEJHIM_01307 0.0 fadD 6.2.1.3 I AMP-binding enzyme
GHJEJHIM_01308 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GHJEJHIM_01309 1.3e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GHJEJHIM_01312 1.9e-294 G Glycosyl hydrolases family 43
GHJEJHIM_01313 2.5e-201 K helix_turn _helix lactose operon repressor
GHJEJHIM_01314 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
GHJEJHIM_01315 2.9e-122 L Protein of unknown function (DUF1524)
GHJEJHIM_01316 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
GHJEJHIM_01317 1.5e-305 EGP Major facilitator Superfamily
GHJEJHIM_01318 1.9e-233
GHJEJHIM_01319 1.3e-110 L Integrase core domain
GHJEJHIM_01320 1.1e-242 EGP Sugar (and other) transporter
GHJEJHIM_01321 4.2e-43 gcvR T Belongs to the UPF0237 family
GHJEJHIM_01322 1.2e-252 S UPF0210 protein
GHJEJHIM_01323 9.9e-109
GHJEJHIM_01324 1.1e-06 S Membrane
GHJEJHIM_01326 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GHJEJHIM_01327 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
GHJEJHIM_01328 4.2e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
GHJEJHIM_01329 3.5e-92
GHJEJHIM_01330 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHJEJHIM_01331 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHJEJHIM_01332 1.3e-96 T Forkhead associated domain
GHJEJHIM_01333 1.1e-67 B Belongs to the OprB family
GHJEJHIM_01334 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
GHJEJHIM_01335 0.0 E Transglutaminase-like superfamily
GHJEJHIM_01336 1.7e-230 S Protein of unknown function DUF58
GHJEJHIM_01337 1.4e-224 S ATPase family associated with various cellular activities (AAA)
GHJEJHIM_01338 0.0 S Fibronectin type 3 domain
GHJEJHIM_01339 2.4e-267 KLT Protein tyrosine kinase
GHJEJHIM_01340 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
GHJEJHIM_01341 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
GHJEJHIM_01342 4.7e-149 K -acetyltransferase
GHJEJHIM_01343 9.9e-250 G Major Facilitator Superfamily
GHJEJHIM_01344 6.4e-24 relB L RelB antitoxin
GHJEJHIM_01345 5.5e-35 L Transposase
GHJEJHIM_01346 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHJEJHIM_01347 8.5e-162 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHJEJHIM_01348 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHJEJHIM_01349 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
GHJEJHIM_01350 6.5e-248 O Subtilase family
GHJEJHIM_01351 4.6e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHJEJHIM_01352 4.4e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHJEJHIM_01353 1.4e-270 S zinc finger
GHJEJHIM_01354 5.9e-112 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
GHJEJHIM_01355 8.3e-229 aspB E Aminotransferase class-V
GHJEJHIM_01356 4.5e-29 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
GHJEJHIM_01357 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
GHJEJHIM_01358 1.1e-130 tmp1 S Domain of unknown function (DUF4391)
GHJEJHIM_01359 2.6e-149 moeB 2.7.7.80 H ThiF family
GHJEJHIM_01360 9.1e-256 cdr OP Sulfurtransferase TusA
GHJEJHIM_01361 5.3e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GHJEJHIM_01363 8.1e-202 S Endonuclease/Exonuclease/phosphatase family
GHJEJHIM_01364 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHJEJHIM_01365 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHJEJHIM_01366 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
GHJEJHIM_01367 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHJEJHIM_01369 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
GHJEJHIM_01370 1e-162
GHJEJHIM_01371 1.9e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
GHJEJHIM_01372 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
GHJEJHIM_01374 1.1e-90 K MarR family
GHJEJHIM_01375 0.0 V ABC transporter, ATP-binding protein
GHJEJHIM_01376 8.2e-41 V ABC transporter transmembrane region
GHJEJHIM_01377 3.9e-30 V ABC transporter transmembrane region
GHJEJHIM_01378 1.3e-42 tnp7109-21 L Integrase core domain
GHJEJHIM_01379 1.4e-20 tnp7109-21 L Integrase core domain
GHJEJHIM_01380 2.6e-109 T protein histidine kinase activity
GHJEJHIM_01381 4.7e-88 K LytTr DNA-binding domain
GHJEJHIM_01382 1e-47 S Protein of unknown function (DUF3073)
GHJEJHIM_01383 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHJEJHIM_01384 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
GHJEJHIM_01385 4.5e-181 S Amidohydrolase family
GHJEJHIM_01386 0.0 yjjP S Threonine/Serine exporter, ThrE
GHJEJHIM_01387 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHJEJHIM_01388 2.1e-238 yhjX EGP Major facilitator Superfamily
GHJEJHIM_01389 0.0 trxB1 1.8.1.9 C Thioredoxin domain
GHJEJHIM_01390 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
GHJEJHIM_01391 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GHJEJHIM_01392 1.4e-93 K helix_turn _helix lactose operon repressor
GHJEJHIM_01393 1.2e-241 ytfL P Transporter associated domain
GHJEJHIM_01394 3.4e-189 yddG EG EamA-like transporter family
GHJEJHIM_01395 1.9e-83 dps P Belongs to the Dps family
GHJEJHIM_01396 2.3e-136 S Protein of unknown function DUF45
GHJEJHIM_01397 5.2e-252 ulaA 2.7.1.194 S PTS system sugar-specific permease component
GHJEJHIM_01398 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
GHJEJHIM_01399 7.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GHJEJHIM_01400 2.3e-190 K helix_turn _helix lactose operon repressor
GHJEJHIM_01401 0.0 G Glycosyl hydrolase family 20, domain 2
GHJEJHIM_01404 0.0 3.2.1.55 GH51 G arabinose metabolic process
GHJEJHIM_01405 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GHJEJHIM_01406 2.5e-124 gntR K FCD
GHJEJHIM_01407 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GHJEJHIM_01409 1.4e-183 L Phage integrase family
GHJEJHIM_01411 2.7e-227
GHJEJHIM_01412 2.6e-185 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
GHJEJHIM_01413 5.1e-270 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
GHJEJHIM_01414 1e-114 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
GHJEJHIM_01415 9.6e-42 S Protein of unknown function (DUF2442)
GHJEJHIM_01416 6.7e-09 K helix_turn _helix lactose operon repressor
GHJEJHIM_01417 6.1e-229 I Serine aminopeptidase, S33
GHJEJHIM_01418 1.1e-185 K Periplasmic binding protein domain
GHJEJHIM_01419 3.5e-187 G Glycosyl hydrolases family 43
GHJEJHIM_01421 1.3e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
GHJEJHIM_01422 1.2e-73 S Transmembrane domain of unknown function (DUF3566)
GHJEJHIM_01423 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHJEJHIM_01424 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHJEJHIM_01425 4.7e-89 S Protein of unknown function (DUF721)
GHJEJHIM_01426 7.2e-231 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GHJEJHIM_01427 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GHJEJHIM_01428 2e-299 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GHJEJHIM_01429 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GHJEJHIM_01430 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
GHJEJHIM_01431 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
GHJEJHIM_01432 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GHJEJHIM_01433 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
GHJEJHIM_01434 6.1e-244 parB K Belongs to the ParB family
GHJEJHIM_01435 5.3e-204 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHJEJHIM_01436 0.0 murJ KLT MviN-like protein
GHJEJHIM_01437 0.0 M Conserved repeat domain
GHJEJHIM_01438 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
GHJEJHIM_01439 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
GHJEJHIM_01440 6.7e-113 S LytR cell envelope-related transcriptional attenuator
GHJEJHIM_01441 7.1e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GHJEJHIM_01442 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GHJEJHIM_01443 3.6e-213 S G5
GHJEJHIM_01445 8.4e-151 O Thioredoxin
GHJEJHIM_01446 0.0 KLT Protein tyrosine kinase
GHJEJHIM_01447 1.2e-174 K Psort location Cytoplasmic, score
GHJEJHIM_01448 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
GHJEJHIM_01449 9.5e-103 L Helix-turn-helix domain
GHJEJHIM_01450 1.4e-170 M Peptidase family M23
GHJEJHIM_01451 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
GHJEJHIM_01452 3.2e-276 G ABC transporter substrate-binding protein
GHJEJHIM_01453 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
GHJEJHIM_01454 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
GHJEJHIM_01455 3.4e-91
GHJEJHIM_01456 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
GHJEJHIM_01457 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHJEJHIM_01458 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
GHJEJHIM_01459 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GHJEJHIM_01460 1e-127 3.2.1.8 S alpha beta
GHJEJHIM_01461 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GHJEJHIM_01462 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GHJEJHIM_01463 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
GHJEJHIM_01464 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GHJEJHIM_01465 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GHJEJHIM_01466 2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GHJEJHIM_01467 1.6e-304 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GHJEJHIM_01468 1.7e-243 G Bacterial extracellular solute-binding protein
GHJEJHIM_01469 1.4e-173 G Binding-protein-dependent transport system inner membrane component
GHJEJHIM_01470 1e-168 G ABC transporter permease
GHJEJHIM_01471 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
GHJEJHIM_01472 6.9e-178 2.7.1.2 GK ROK family
GHJEJHIM_01473 6.4e-218 GK ROK family
GHJEJHIM_01474 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
GHJEJHIM_01475 3.3e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GHJEJHIM_01476 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GHJEJHIM_01477 8.9e-303 ybiT S ABC transporter
GHJEJHIM_01478 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GHJEJHIM_01479 1.9e-240 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GHJEJHIM_01480 1.6e-117 K Transcriptional regulatory protein, C terminal
GHJEJHIM_01481 2.3e-58 V MacB-like periplasmic core domain
GHJEJHIM_01482 6.1e-77
GHJEJHIM_01483 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHJEJHIM_01484 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHJEJHIM_01485 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
GHJEJHIM_01486 1.5e-177 rapZ S Displays ATPase and GTPase activities
GHJEJHIM_01487 2e-172 whiA K May be required for sporulation
GHJEJHIM_01488 1.1e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
GHJEJHIM_01489 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHJEJHIM_01490 8e-33 secG U Preprotein translocase SecG subunit
GHJEJHIM_01491 3.4e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GHJEJHIM_01492 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
GHJEJHIM_01493 3.1e-243 mepA_6 V MatE
GHJEJHIM_01496 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
GHJEJHIM_01497 1.1e-142 yoaK S Protein of unknown function (DUF1275)
GHJEJHIM_01498 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GHJEJHIM_01499 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
GHJEJHIM_01500 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GHJEJHIM_01501 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GHJEJHIM_01502 7.1e-160 G Fructosamine kinase
GHJEJHIM_01503 2.5e-167 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GHJEJHIM_01504 3.7e-156 S PAC2 family
GHJEJHIM_01506 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GHJEJHIM_01507 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
GHJEJHIM_01508 1.5e-158 yeaZ 2.3.1.234 O Glycoprotease family
GHJEJHIM_01509 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
GHJEJHIM_01510 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
GHJEJHIM_01511 0.0 comE S Competence protein
GHJEJHIM_01512 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
GHJEJHIM_01513 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHJEJHIM_01514 5.8e-169 ET Bacterial periplasmic substrate-binding proteins
GHJEJHIM_01515 3.7e-171 corA P CorA-like Mg2+ transporter protein
GHJEJHIM_01516 1e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GHJEJHIM_01517 5.9e-299 E Serine carboxypeptidase
GHJEJHIM_01518 0.0 S Psort location Cytoplasmic, score 8.87
GHJEJHIM_01519 1.6e-108 S Domain of unknown function (DUF4194)
GHJEJHIM_01520 8.8e-284 S Psort location Cytoplasmic, score 8.87
GHJEJHIM_01521 2.1e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GHJEJHIM_01522 2.4e-62 yeaO K Protein of unknown function, DUF488
GHJEJHIM_01523 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
GHJEJHIM_01524 1.2e-97 MA20_25245 K FR47-like protein
GHJEJHIM_01525 1.1e-56 K Transcriptional regulator
GHJEJHIM_01526 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
GHJEJHIM_01527 2.7e-38 J Aminoacyl-tRNA editing domain
GHJEJHIM_01528 1.2e-182 S Acetyltransferase (GNAT) domain
GHJEJHIM_01529 2.1e-131 S SOS response associated peptidase (SRAP)
GHJEJHIM_01530 6.5e-125
GHJEJHIM_01531 7.3e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GHJEJHIM_01532 9.8e-164 rpoC M heme binding
GHJEJHIM_01533 3e-28 EGP Major facilitator Superfamily
GHJEJHIM_01534 1.2e-97 EGP Major facilitator Superfamily
GHJEJHIM_01536 8.9e-159
GHJEJHIM_01537 6.4e-90 ypjC S Putative ABC-transporter type IV
GHJEJHIM_01538 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
GHJEJHIM_01539 3.7e-193 V VanZ like family
GHJEJHIM_01540 3.5e-146 KT RESPONSE REGULATOR receiver
GHJEJHIM_01541 2.7e-70 pdxH S Pfam:Pyridox_oxidase
GHJEJHIM_01542 5.7e-142 yijF S Domain of unknown function (DUF1287)
GHJEJHIM_01543 1.9e-132 C Putative TM nitroreductase
GHJEJHIM_01544 5.7e-108
GHJEJHIM_01546 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
GHJEJHIM_01547 2.9e-78 S Bacterial PH domain
GHJEJHIM_01548 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GHJEJHIM_01549 4.6e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GHJEJHIM_01550 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHJEJHIM_01552 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHJEJHIM_01553 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GHJEJHIM_01554 8.9e-93
GHJEJHIM_01555 1.5e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GHJEJHIM_01556 1.7e-284 thrC 4.2.3.1 E Threonine synthase N terminus
GHJEJHIM_01557 4e-122 S ABC-2 family transporter protein
GHJEJHIM_01558 3.4e-124 S ABC-2 family transporter protein
GHJEJHIM_01559 3.3e-175 V ATPases associated with a variety of cellular activities
GHJEJHIM_01560 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
GHJEJHIM_01561 3.4e-123 S Haloacid dehalogenase-like hydrolase
GHJEJHIM_01562 1.2e-292 recN L May be involved in recombinational repair of damaged DNA
GHJEJHIM_01563 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GHJEJHIM_01564 3.9e-236 trkB P Cation transport protein
GHJEJHIM_01565 6.8e-116 trkA P TrkA-N domain
GHJEJHIM_01566 2.2e-101
GHJEJHIM_01567 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GHJEJHIM_01569 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GHJEJHIM_01570 5.4e-156 L Tetratricopeptide repeat
GHJEJHIM_01571 2e-88 K Putative zinc ribbon domain
GHJEJHIM_01572 7.2e-126 S GyrI-like small molecule binding domain
GHJEJHIM_01573 3.7e-91 L DNA integration
GHJEJHIM_01574 5.5e-15
GHJEJHIM_01575 7.3e-62
GHJEJHIM_01576 2.7e-120 K helix_turn_helix, mercury resistance
GHJEJHIM_01577 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
GHJEJHIM_01578 3.4e-141 S Bacterial protein of unknown function (DUF881)
GHJEJHIM_01579 2.6e-31 sbp S Protein of unknown function (DUF1290)
GHJEJHIM_01580 3.1e-173 S Bacterial protein of unknown function (DUF881)
GHJEJHIM_01581 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHJEJHIM_01582 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
GHJEJHIM_01583 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
GHJEJHIM_01584 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
GHJEJHIM_01585 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GHJEJHIM_01586 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GHJEJHIM_01587 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GHJEJHIM_01588 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
GHJEJHIM_01589 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHJEJHIM_01590 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GHJEJHIM_01591 5.7e-30
GHJEJHIM_01592 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GHJEJHIM_01593 5e-246
GHJEJHIM_01594 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GHJEJHIM_01595 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GHJEJHIM_01596 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GHJEJHIM_01597 2.6e-44 yajC U Preprotein translocase subunit
GHJEJHIM_01598 5.1e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GHJEJHIM_01599 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GHJEJHIM_01601 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GHJEJHIM_01602 1e-131 yebC K transcriptional regulatory protein
GHJEJHIM_01603 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
GHJEJHIM_01604 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHJEJHIM_01605 4.9e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GHJEJHIM_01608 2.6e-270
GHJEJHIM_01610 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
GHJEJHIM_01611 1.8e-110 aspA 3.6.1.13 L NUDIX domain
GHJEJHIM_01613 9.2e-120 pdtaR T Response regulator receiver domain protein
GHJEJHIM_01614 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHJEJHIM_01615 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
GHJEJHIM_01616 1.9e-127 3.6.1.13 L NUDIX domain
GHJEJHIM_01617 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GHJEJHIM_01618 3.6e-219 ykiI
GHJEJHIM_01620 4.2e-135 L Phage integrase family
GHJEJHIM_01621 2.9e-108 3.4.13.21 E Peptidase family S51
GHJEJHIM_01622 1.2e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GHJEJHIM_01623 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHJEJHIM_01624 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GHJEJHIM_01625 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
GHJEJHIM_01626 1.7e-122
GHJEJHIM_01628 9.9e-112 ysdA S Protein of unknown function (DUF1294)
GHJEJHIM_01629 1.3e-31
GHJEJHIM_01631 3.2e-55
GHJEJHIM_01634 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GHJEJHIM_01635 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
GHJEJHIM_01636 3.4e-189 pit P Phosphate transporter family
GHJEJHIM_01637 1.1e-115 MA20_27875 P Protein of unknown function DUF47
GHJEJHIM_01638 3.1e-119 K helix_turn_helix, Lux Regulon
GHJEJHIM_01639 9.2e-234 T Histidine kinase
GHJEJHIM_01640 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
GHJEJHIM_01641 1.4e-178 V ATPases associated with a variety of cellular activities
GHJEJHIM_01642 1.1e-163 T Pfam Adenylate and Guanylate cyclase catalytic domain
GHJEJHIM_01643 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
GHJEJHIM_01644 1.1e-79 ssb1 L Single-stranded DNA-binding protein
GHJEJHIM_01645 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHJEJHIM_01646 1.9e-69 rplI J Binds to the 23S rRNA
GHJEJHIM_01647 2e-35 S Parallel beta-helix repeats
GHJEJHIM_01648 6.1e-67 E Domain of unknown function (DUF5011)
GHJEJHIM_01650 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GHJEJHIM_01651 3.9e-129 M Protein of unknown function (DUF3152)
GHJEJHIM_01652 9.2e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHJEJHIM_01653 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GHJEJHIM_01654 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
GHJEJHIM_01655 0.0 inlJ M domain protein
GHJEJHIM_01656 7.9e-283 M LPXTG cell wall anchor motif
GHJEJHIM_01657 3.6e-216 3.4.22.70 M Sortase family
GHJEJHIM_01658 8.5e-60 S Domain of unknown function (DUF4854)
GHJEJHIM_01659 2.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
GHJEJHIM_01660 2.5e-30 2.1.1.72 S Protein conserved in bacteria
GHJEJHIM_01661 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHJEJHIM_01662 1.6e-132 M Mechanosensitive ion channel
GHJEJHIM_01663 3.8e-119 K Bacterial regulatory proteins, tetR family
GHJEJHIM_01664 8.5e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
GHJEJHIM_01665 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
GHJEJHIM_01666 3.2e-15
GHJEJHIM_01668 0.0 fadD 6.2.1.3 I AMP-binding enzyme
GHJEJHIM_01670 1.4e-27
GHJEJHIM_01671 5e-179 S G5
GHJEJHIM_01672 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
GHJEJHIM_01673 1.4e-118 F Domain of unknown function (DUF4916)
GHJEJHIM_01674 4.9e-159 mhpC I Alpha/beta hydrolase family
GHJEJHIM_01675 1.1e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
GHJEJHIM_01676 0.0 enhA_2 S L,D-transpeptidase catalytic domain
GHJEJHIM_01677 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
GHJEJHIM_01678 1.1e-240 S Uncharacterized conserved protein (DUF2183)
GHJEJHIM_01679 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
GHJEJHIM_01680 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GHJEJHIM_01681 2.2e-119 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
GHJEJHIM_01682 3.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
GHJEJHIM_01683 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
GHJEJHIM_01684 2.5e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
GHJEJHIM_01685 3.3e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
GHJEJHIM_01686 3.1e-139 glpR K DeoR C terminal sensor domain
GHJEJHIM_01687 1.2e-251 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
GHJEJHIM_01688 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
GHJEJHIM_01689 3.6e-165 L Psort location Cytoplasmic, score
GHJEJHIM_01690 9.5e-35 S Psort location Cytoplasmic, score
GHJEJHIM_01691 1.4e-57 S Protein of unknown function (DUF3801)
GHJEJHIM_01692 0.0 U Type IV secretory system Conjugative DNA transfer
GHJEJHIM_01693 1.6e-17 S Maff2 family
GHJEJHIM_01694 9.1e-116 parA D AAA domain
GHJEJHIM_01695 4.1e-89 S Transcription factor WhiB
GHJEJHIM_01696 7.4e-42
GHJEJHIM_01697 4.8e-178 S Helix-turn-helix domain
GHJEJHIM_01698 1.9e-26
GHJEJHIM_01699 1.6e-116
GHJEJHIM_01700 3.3e-123
GHJEJHIM_01701 1.7e-68
GHJEJHIM_01702 7.3e-192 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHJEJHIM_01703 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
GHJEJHIM_01704 1.6e-41 P ABC-type metal ion transport system permease component
GHJEJHIM_01705 6.3e-10 P ABC-type metal ion transport system permease component
GHJEJHIM_01706 5e-223 S Peptidase dimerisation domain
GHJEJHIM_01707 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GHJEJHIM_01708 6.4e-40
GHJEJHIM_01709 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
GHJEJHIM_01710 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHJEJHIM_01711 4.4e-114 S Protein of unknown function (DUF3000)
GHJEJHIM_01712 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
GHJEJHIM_01713 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHJEJHIM_01714 3.6e-255 clcA_2 P Voltage gated chloride channel
GHJEJHIM_01715 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHJEJHIM_01716 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHJEJHIM_01717 9.1e-245 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GHJEJHIM_01718 3e-30 V ABC transporter transmembrane region
GHJEJHIM_01720 1.3e-25 V ABC transporter transmembrane region
GHJEJHIM_01721 0.0 V ABC transporter, ATP-binding protein
GHJEJHIM_01722 3.3e-84 K MarR family
GHJEJHIM_01723 2.5e-143 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
GHJEJHIM_01724 6.7e-27 K Bacterial regulatory proteins, tetR family
GHJEJHIM_01725 1.8e-195 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
GHJEJHIM_01726 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
GHJEJHIM_01727 1.1e-43 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
GHJEJHIM_01728 7.3e-239 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
GHJEJHIM_01729 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
GHJEJHIM_01730 5.6e-54
GHJEJHIM_01731 8.8e-156 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
GHJEJHIM_01732 8.9e-144 cobB2 K Sir2 family
GHJEJHIM_01733 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
GHJEJHIM_01734 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GHJEJHIM_01735 1.2e-145 ypfH S Phospholipase/Carboxylesterase
GHJEJHIM_01736 0.0 yjcE P Sodium/hydrogen exchanger family
GHJEJHIM_01737 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
GHJEJHIM_01738 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
GHJEJHIM_01739 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
GHJEJHIM_01741 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHJEJHIM_01742 2e-269 KLT Domain of unknown function (DUF4032)
GHJEJHIM_01743 1.1e-45
GHJEJHIM_01744 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
GHJEJHIM_01745 8e-70 S Protein of unknown function (DUF4235)
GHJEJHIM_01746 1.8e-138 G Phosphoglycerate mutase family
GHJEJHIM_01748 1.6e-188 K Psort location Cytoplasmic, score
GHJEJHIM_01749 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
GHJEJHIM_01750 0.0 dnaK O Heat shock 70 kDa protein
GHJEJHIM_01751 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GHJEJHIM_01752 1.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
GHJEJHIM_01753 5.2e-87 hspR K transcriptional regulator, MerR family
GHJEJHIM_01754 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
GHJEJHIM_01755 3.5e-195 ybiR P Citrate transporter
GHJEJHIM_01756 5.2e-85 S AAA domain
GHJEJHIM_01757 1.7e-147 4.2.1.48 S Domain of unknown function (DUF4392)
GHJEJHIM_01758 6.1e-236 bccA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Biotin carboxylase C-terminal domain
GHJEJHIM_01759 1.6e-190 ybgK E Allophanate hydrolase subunit 2
GHJEJHIM_01760 2.5e-117 lamB S LamB/YcsF family
GHJEJHIM_01761 5.2e-137 S Protein of unknown function (DUF1445)
GHJEJHIM_01762 8e-166 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
GHJEJHIM_01763 3.6e-13 V peptidase activity
GHJEJHIM_01764 6.7e-91 L Integrase core domain
GHJEJHIM_01765 8.6e-204 K helix_turn _helix lactose operon repressor
GHJEJHIM_01766 1.8e-70 G Glycosyl hydrolase family 85
GHJEJHIM_01767 7.7e-303 G Glycosyl hydrolase family 85
GHJEJHIM_01768 6e-177 endOF2 3.2.1.14, 3.2.1.52, 3.2.1.96 GH18,GH20 G Glycosyl hydrolase, family 20, catalytic domain
GHJEJHIM_01769 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
GHJEJHIM_01770 1.4e-180 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
GHJEJHIM_01771 6.6e-190 3.4.13.19 E Dipeptidase
GHJEJHIM_01772 2.1e-170 dmpA 3.4.11.19 EQ Peptidase family S58
GHJEJHIM_01773 5.8e-55 ybiR P Citrate transporter
GHJEJHIM_01774 6e-262 E ABC transporter, substrate-binding protein, family 5
GHJEJHIM_01775 2.3e-248 srrA1 G Bacterial extracellular solute-binding protein
GHJEJHIM_01776 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
GHJEJHIM_01777 5e-293 pacL2 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)