ORF_ID e_value Gene_name EC_number CAZy COGs Description
DFGHHELI_00005 7.8e-08
DFGHHELI_00013 2e-08
DFGHHELI_00017 1.3e-142 spo0M S COG4326 Sporulation control protein
DFGHHELI_00018 1.2e-26
DFGHHELI_00019 3.9e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
DFGHHELI_00020 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DFGHHELI_00021 3.4e-263 ygaK C Berberine and berberine like
DFGHHELI_00023 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
DFGHHELI_00024 3.9e-146 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
DFGHHELI_00025 4.3e-170 ssuA M Sulfonate ABC transporter
DFGHHELI_00026 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DFGHHELI_00027 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
DFGHHELI_00029 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DFGHHELI_00030 2.6e-77 ygaO
DFGHHELI_00031 4.4e-29 K Transcriptional regulator
DFGHHELI_00033 2.3e-113 yhzB S B3/4 domain
DFGHHELI_00034 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DFGHHELI_00035 9.1e-175 yhbB S Putative amidase domain
DFGHHELI_00036 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DFGHHELI_00037 6e-109 yhbD K Protein of unknown function (DUF4004)
DFGHHELI_00038 6.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
DFGHHELI_00039 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
DFGHHELI_00040 0.0 prkA T Ser protein kinase
DFGHHELI_00041 2.5e-225 yhbH S Belongs to the UPF0229 family
DFGHHELI_00042 2.2e-76 yhbI K DNA-binding transcription factor activity
DFGHHELI_00043 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
DFGHHELI_00044 3.1e-271 yhcA EGP Major facilitator Superfamily
DFGHHELI_00045 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
DFGHHELI_00046 2.8e-37 yhcC
DFGHHELI_00047 3.5e-55
DFGHHELI_00048 1.5e-59 yhcF K Transcriptional regulator
DFGHHELI_00049 4.4e-121 yhcG V ABC transporter, ATP-binding protein
DFGHHELI_00050 2.2e-165 yhcH V ABC transporter, ATP-binding protein
DFGHHELI_00051 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DFGHHELI_00052 1e-30 cspB K Cold-shock protein
DFGHHELI_00053 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
DFGHHELI_00054 1.1e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
DFGHHELI_00055 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFGHHELI_00056 1.1e-40 yhcM
DFGHHELI_00057 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DFGHHELI_00058 5.6e-167 yhcP
DFGHHELI_00059 1.5e-99 yhcQ M Spore coat protein
DFGHHELI_00060 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
DFGHHELI_00061 3.5e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
DFGHHELI_00062 1.9e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DFGHHELI_00063 9.3e-68 yhcU S Family of unknown function (DUF5365)
DFGHHELI_00064 9.9e-68 yhcV S COG0517 FOG CBS domain
DFGHHELI_00065 1.3e-119 yhcW 5.4.2.6 S hydrolase
DFGHHELI_00066 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DFGHHELI_00067 3e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DFGHHELI_00068 9.9e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DFGHHELI_00069 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
DFGHHELI_00070 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DFGHHELI_00071 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DFGHHELI_00072 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
DFGHHELI_00073 6.7e-212 yhcY 2.7.13.3 T Histidine kinase
DFGHHELI_00074 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_00075 7.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
DFGHHELI_00076 1.2e-38 yhdB S YhdB-like protein
DFGHHELI_00077 1.8e-53 yhdC S Protein of unknown function (DUF3889)
DFGHHELI_00078 5.7e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DFGHHELI_00079 1e-75 nsrR K Transcriptional regulator
DFGHHELI_00080 1.5e-238 ygxB M Conserved TM helix
DFGHHELI_00081 2.1e-276 ycgB S Stage V sporulation protein R
DFGHHELI_00082 1.7e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
DFGHHELI_00083 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DFGHHELI_00084 3.8e-162 citR K Transcriptional regulator
DFGHHELI_00085 4.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
DFGHHELI_00086 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_00087 3.4e-250 yhdG E amino acid
DFGHHELI_00088 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DFGHHELI_00089 2.3e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_00090 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_00091 8.1e-45 yhdK S Sigma-M inhibitor protein
DFGHHELI_00092 6.6e-201 yhdL S Sigma factor regulator N-terminal
DFGHHELI_00093 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_00094 1.5e-191 yhdN C Aldo keto reductase
DFGHHELI_00095 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DFGHHELI_00096 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DFGHHELI_00097 4.7e-74 cueR K transcriptional
DFGHHELI_00098 2e-222 yhdR 2.6.1.1 E Aminotransferase
DFGHHELI_00099 8.7e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
DFGHHELI_00100 4.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFGHHELI_00101 1.5e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFGHHELI_00102 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DFGHHELI_00104 9.6e-203 yhdY M Mechanosensitive ion channel
DFGHHELI_00105 8.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DFGHHELI_00106 6.3e-146 yheN G deacetylase
DFGHHELI_00107 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
DFGHHELI_00108 8.6e-230 nhaC C Na H antiporter
DFGHHELI_00109 3.2e-82 nhaX T Belongs to the universal stress protein A family
DFGHHELI_00110 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
DFGHHELI_00111 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
DFGHHELI_00112 1e-108 yheG GM NAD(P)H-binding
DFGHHELI_00113 6.3e-28 sspB S spore protein
DFGHHELI_00114 1.3e-36 yheE S Family of unknown function (DUF5342)
DFGHHELI_00115 5.1e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
DFGHHELI_00116 4.3e-216 yheC HJ YheC/D like ATP-grasp
DFGHHELI_00117 2.2e-202 yheB S Belongs to the UPF0754 family
DFGHHELI_00118 9.5e-48 yheA S Belongs to the UPF0342 family
DFGHHELI_00119 7.5e-205 yhaZ L DNA alkylation repair enzyme
DFGHHELI_00120 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
DFGHHELI_00121 3.9e-292 hemZ H coproporphyrinogen III oxidase
DFGHHELI_00122 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
DFGHHELI_00123 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
DFGHHELI_00125 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
DFGHHELI_00126 1.1e-26 S YhzD-like protein
DFGHHELI_00127 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
DFGHHELI_00128 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
DFGHHELI_00129 2.4e-223 yhaO L DNA repair exonuclease
DFGHHELI_00130 0.0 yhaN L AAA domain
DFGHHELI_00131 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
DFGHHELI_00132 1.6e-21 yhaL S Sporulation protein YhaL
DFGHHELI_00133 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DFGHHELI_00134 1.1e-89 yhaK S Putative zincin peptidase
DFGHHELI_00135 1.3e-54 yhaI S Protein of unknown function (DUF1878)
DFGHHELI_00136 1e-113 hpr K Negative regulator of protease production and sporulation
DFGHHELI_00137 7e-39 yhaH S YtxH-like protein
DFGHHELI_00138 5.4e-21
DFGHHELI_00139 3.6e-80 trpP S Tryptophan transporter TrpP
DFGHHELI_00140 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DFGHHELI_00141 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DFGHHELI_00142 4.6e-137 ecsA V transporter (ATP-binding protein)
DFGHHELI_00143 3.5e-214 ecsB U ABC transporter
DFGHHELI_00144 3.4e-113 ecsC S EcsC protein family
DFGHHELI_00145 1.2e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DFGHHELI_00146 3.5e-231 yhfA C membrane
DFGHHELI_00147 1.2e-30 1.15.1.2 C Rubrerythrin
DFGHHELI_00148 3.7e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
DFGHHELI_00149 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DFGHHELI_00150 2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DFGHHELI_00151 5.2e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DFGHHELI_00152 1.5e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DFGHHELI_00153 4.6e-100 yhgD K Transcriptional regulator
DFGHHELI_00154 4.6e-215 yhgE S YhgE Pip N-terminal domain protein
DFGHHELI_00155 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DFGHHELI_00156 2.2e-137 yhfC S Putative membrane peptidase family (DUF2324)
DFGHHELI_00157 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
DFGHHELI_00158 1.1e-71 3.4.13.21 S ASCH
DFGHHELI_00159 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFGHHELI_00160 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
DFGHHELI_00161 3.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
DFGHHELI_00162 1.3e-111 yhfK GM NmrA-like family
DFGHHELI_00163 2.8e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
DFGHHELI_00164 1.9e-65 yhfM
DFGHHELI_00165 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
DFGHHELI_00166 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
DFGHHELI_00167 2.8e-76 VY92_01935 K acetyltransferase
DFGHHELI_00168 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
DFGHHELI_00169 2.1e-158 yfmC M Periplasmic binding protein
DFGHHELI_00170 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
DFGHHELI_00171 3.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
DFGHHELI_00172 7.8e-274 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
DFGHHELI_00173 7.2e-90 bioY S BioY family
DFGHHELI_00174 1.7e-182 hemAT NT chemotaxis protein
DFGHHELI_00175 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
DFGHHELI_00176 6.7e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_00177 1.3e-32 yhzC S IDEAL
DFGHHELI_00178 4.2e-109 comK K Competence transcription factor
DFGHHELI_00179 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
DFGHHELI_00180 1.6e-39 yhjA S Excalibur calcium-binding domain
DFGHHELI_00181 4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFGHHELI_00182 6.9e-27 yhjC S Protein of unknown function (DUF3311)
DFGHHELI_00183 6.7e-60 yhjD
DFGHHELI_00184 5.9e-109 yhjE S SNARE associated Golgi protein
DFGHHELI_00185 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
DFGHHELI_00186 4.5e-280 yhjG CH FAD binding domain
DFGHHELI_00187 2.9e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_00190 7.2e-212 glcP G Major Facilitator Superfamily
DFGHHELI_00191 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
DFGHHELI_00192 1.7e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
DFGHHELI_00193 1.6e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
DFGHHELI_00194 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
DFGHHELI_00195 4.2e-201 abrB S membrane
DFGHHELI_00196 9.3e-212 EGP Transmembrane secretion effector
DFGHHELI_00197 0.0 S Sugar transport-related sRNA regulator N-term
DFGHHELI_00198 2.2e-78 yhjR S Rubrerythrin
DFGHHELI_00199 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
DFGHHELI_00200 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DFGHHELI_00201 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DFGHHELI_00202 0.0 sbcC L COG0419 ATPase involved in DNA repair
DFGHHELI_00203 1.1e-49 yisB V COG1403 Restriction endonuclease
DFGHHELI_00204 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
DFGHHELI_00205 5.3e-63 gerPE S Spore germination protein GerPE
DFGHHELI_00206 3.1e-23 gerPD S Spore germination protein
DFGHHELI_00207 5.3e-54 gerPC S Spore germination protein
DFGHHELI_00208 4e-34 gerPB S cell differentiation
DFGHHELI_00209 1.9e-33 gerPA S Spore germination protein
DFGHHELI_00210 1.5e-22 yisI S Spo0E like sporulation regulatory protein
DFGHHELI_00211 9.1e-175 cotH M Spore Coat
DFGHHELI_00212 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
DFGHHELI_00213 3e-57 yisL S UPF0344 protein
DFGHHELI_00214 0.0 wprA O Belongs to the peptidase S8 family
DFGHHELI_00215 1.8e-101 yisN S Protein of unknown function (DUF2777)
DFGHHELI_00216 0.0 asnO 6.3.5.4 E Asparagine synthase
DFGHHELI_00217 1.3e-113 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
DFGHHELI_00218 1.5e-242 yisQ V Mate efflux family protein
DFGHHELI_00219 1.2e-160 yisR K Transcriptional regulator
DFGHHELI_00220 2.4e-184 purR K helix_turn _helix lactose operon repressor
DFGHHELI_00221 1.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
DFGHHELI_00222 5.3e-92 yisT S DinB family
DFGHHELI_00223 1.1e-104 argO S Lysine exporter protein LysE YggA
DFGHHELI_00224 5.3e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_00225 4e-36 mcbG S Pentapeptide repeats (9 copies)
DFGHHELI_00226 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DFGHHELI_00227 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
DFGHHELI_00228 6.2e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
DFGHHELI_00229 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
DFGHHELI_00230 1.4e-119 comB 3.1.3.71 H Belongs to the ComB family
DFGHHELI_00231 1.6e-140 yitD 4.4.1.19 S synthase
DFGHHELI_00232 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DFGHHELI_00233 6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DFGHHELI_00234 1.5e-228 yitG EGP Major facilitator Superfamily
DFGHHELI_00235 1.2e-157 yitH K Acetyltransferase (GNAT) domain
DFGHHELI_00236 9.2e-72 yjcF S Acetyltransferase (GNAT) domain
DFGHHELI_00237 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DFGHHELI_00238 5.6e-54 yajQ S Belongs to the UPF0234 family
DFGHHELI_00239 1.1e-158 cvfB S protein conserved in bacteria
DFGHHELI_00240 8.5e-94
DFGHHELI_00241 3.6e-171
DFGHHELI_00242 1.5e-97 S Sporulation delaying protein SdpA
DFGHHELI_00243 1.5e-58 K Transcriptional regulator PadR-like family
DFGHHELI_00244 2.5e-93
DFGHHELI_00245 1.4e-44 yitR S Domain of unknown function (DUF3784)
DFGHHELI_00246 1.1e-308 nprB 3.4.24.28 E Peptidase M4
DFGHHELI_00247 8.4e-159 yitS S protein conserved in bacteria
DFGHHELI_00248 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
DFGHHELI_00249 5e-73 ipi S Intracellular proteinase inhibitor
DFGHHELI_00250 1.2e-17 S Protein of unknown function (DUF3813)
DFGHHELI_00252 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
DFGHHELI_00253 7.6e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
DFGHHELI_00254 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
DFGHHELI_00255 1.5e-22 pilT S Proteolipid membrane potential modulator
DFGHHELI_00256 1.6e-266 yitY C D-arabinono-1,4-lactone oxidase
DFGHHELI_00257 3.8e-88 norB G Major Facilitator Superfamily
DFGHHELI_00258 2.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DFGHHELI_00259 5e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DFGHHELI_00260 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DFGHHELI_00261 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
DFGHHELI_00262 2.8e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DFGHHELI_00263 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
DFGHHELI_00264 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DFGHHELI_00265 9.5e-28 yjzC S YjzC-like protein
DFGHHELI_00266 2.3e-16 yjzD S Protein of unknown function (DUF2929)
DFGHHELI_00267 1.1e-141 yjaU I carboxylic ester hydrolase activity
DFGHHELI_00268 1.5e-100 yjaV
DFGHHELI_00269 2.5e-183 med S Transcriptional activator protein med
DFGHHELI_00270 7.3e-26 comZ S ComZ
DFGHHELI_00271 2.7e-22 yjzB
DFGHHELI_00272 8.7e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DFGHHELI_00273 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DFGHHELI_00274 2.5e-149 yjaZ O Zn-dependent protease
DFGHHELI_00275 1.8e-184 appD P Belongs to the ABC transporter superfamily
DFGHHELI_00276 4.7e-185 appF E Belongs to the ABC transporter superfamily
DFGHHELI_00277 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
DFGHHELI_00278 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00279 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00280 5e-147 yjbA S Belongs to the UPF0736 family
DFGHHELI_00281 6.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
DFGHHELI_00282 0.0 oppA E ABC transporter substrate-binding protein
DFGHHELI_00283 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00284 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00285 3e-198 oppD P Belongs to the ABC transporter superfamily
DFGHHELI_00286 1.2e-171 oppF E Belongs to the ABC transporter superfamily
DFGHHELI_00287 4.7e-194 yjbB EGP Major Facilitator Superfamily
DFGHHELI_00288 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_00289 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DFGHHELI_00290 6e-112 yjbE P Integral membrane protein TerC family
DFGHHELI_00291 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DFGHHELI_00292 5.8e-219 yjbF S Competence protein
DFGHHELI_00293 0.0 pepF E oligoendopeptidase F
DFGHHELI_00294 1.8e-20
DFGHHELI_00296 8e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
DFGHHELI_00297 3.7e-72 yjbI S Bacterial-like globin
DFGHHELI_00298 8.2e-86 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DFGHHELI_00299 4.1e-101 yjbK S protein conserved in bacteria
DFGHHELI_00300 7.1e-62 yjbL S Belongs to the UPF0738 family
DFGHHELI_00301 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
DFGHHELI_00302 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DFGHHELI_00303 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DFGHHELI_00304 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
DFGHHELI_00305 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DFGHHELI_00306 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DFGHHELI_00307 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
DFGHHELI_00308 1.2e-216 thiO 1.4.3.19 E Glycine oxidase
DFGHHELI_00309 1.5e-29 thiS H thiamine diphosphate biosynthetic process
DFGHHELI_00310 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DFGHHELI_00311 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DFGHHELI_00312 4.4e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DFGHHELI_00313 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DFGHHELI_00314 5.9e-54 yjbX S Spore coat protein
DFGHHELI_00315 5.2e-83 cotZ S Spore coat protein
DFGHHELI_00316 3.4e-96 cotY S Spore coat protein Z
DFGHHELI_00317 6.4e-77 cotX S Spore Coat Protein X and V domain
DFGHHELI_00318 8.5e-32 cotW
DFGHHELI_00319 2.3e-55 cotV S Spore Coat Protein X and V domain
DFGHHELI_00320 4.3e-56 yjcA S Protein of unknown function (DUF1360)
DFGHHELI_00323 2.9e-38 spoVIF S Stage VI sporulation protein F
DFGHHELI_00324 0.0 yjcD 3.6.4.12 L DNA helicase
DFGHHELI_00325 3.2e-37
DFGHHELI_00326 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_00327 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
DFGHHELI_00328 1.9e-135 yjcH P COG2382 Enterochelin esterase and related enzymes
DFGHHELI_00329 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DFGHHELI_00330 1.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DFGHHELI_00331 3.5e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
DFGHHELI_00332 1.9e-209 yjcL S Protein of unknown function (DUF819)
DFGHHELI_00335 1.6e-38
DFGHHELI_00336 1e-29
DFGHHELI_00337 7e-240 M nucleic acid phosphodiester bond hydrolysis
DFGHHELI_00338 4.9e-21
DFGHHELI_00341 4.9e-170 S response regulator aspartate phosphatase
DFGHHELI_00342 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
DFGHHELI_00343 2.6e-44 yjcN
DFGHHELI_00344 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
DFGHHELI_00345 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
DFGHHELI_00346 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
DFGHHELI_00347 2.5e-47 yjdF S Protein of unknown function (DUF2992)
DFGHHELI_00348 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
DFGHHELI_00350 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DFGHHELI_00351 7.1e-29 S Domain of unknown function (DUF4177)
DFGHHELI_00352 1.5e-50 yjdJ S Domain of unknown function (DUF4306)
DFGHHELI_00353 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DFGHHELI_00355 3.2e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
DFGHHELI_00356 1.8e-81 S Protein of unknown function (DUF2690)
DFGHHELI_00357 2.3e-20 yjfB S Putative motility protein
DFGHHELI_00358 1.8e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
DFGHHELI_00359 1.2e-45 T PhoQ Sensor
DFGHHELI_00360 2e-103 yjgB S Domain of unknown function (DUF4309)
DFGHHELI_00361 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
DFGHHELI_00362 1.5e-92 yjgD S Protein of unknown function (DUF1641)
DFGHHELI_00363 4.5e-10 S Domain of unknown function (DUF4352)
DFGHHELI_00364 7.8e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
DFGHHELI_00366 4e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
DFGHHELI_00367 1.5e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DFGHHELI_00368 8.2e-30
DFGHHELI_00369 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
DFGHHELI_00370 1.6e-121 ybbM S transport system, permease component
DFGHHELI_00371 9.8e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
DFGHHELI_00372 2.9e-90 yjlB S Cupin domain
DFGHHELI_00373 7.1e-66 yjlC S Protein of unknown function (DUF1641)
DFGHHELI_00374 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
DFGHHELI_00375 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
DFGHHELI_00376 9.2e-248 yjmB G symporter YjmB
DFGHHELI_00377 1.8e-187 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
DFGHHELI_00378 3.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
DFGHHELI_00379 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
DFGHHELI_00380 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_00381 1.1e-226 exuT G Sugar (and other) transporter
DFGHHELI_00382 6.8e-184 exuR K transcriptional
DFGHHELI_00383 2.2e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
DFGHHELI_00384 1.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
DFGHHELI_00385 4.3e-130 MA20_18170 S membrane transporter protein
DFGHHELI_00386 2.3e-78 yjoA S DinB family
DFGHHELI_00387 4.7e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
DFGHHELI_00388 8.7e-212 S response regulator aspartate phosphatase
DFGHHELI_00390 2.4e-40 S YCII-related domain
DFGHHELI_00391 2.7e-161 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
DFGHHELI_00392 2e-59 yjqA S Bacterial PH domain
DFGHHELI_00393 1e-110 yjqB S Pfam:DUF867
DFGHHELI_00394 4.4e-160 ydbD P Catalase
DFGHHELI_00395 2.3e-110 xkdA E IrrE N-terminal-like domain
DFGHHELI_00396 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
DFGHHELI_00398 2.3e-156 xkdB K sequence-specific DNA binding
DFGHHELI_00399 6.4e-119 xkdC L Bacterial dnaA protein
DFGHHELI_00402 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
DFGHHELI_00403 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
DFGHHELI_00404 4.1e-139 xtmA L phage terminase small subunit
DFGHHELI_00405 1.8e-253 xtmB S phage terminase, large subunit
DFGHHELI_00406 4.6e-285 yqbA S portal protein
DFGHHELI_00407 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
DFGHHELI_00408 1.7e-168 xkdG S Phage capsid family
DFGHHELI_00409 5.1e-63 yqbG S Protein of unknown function (DUF3199)
DFGHHELI_00410 2.5e-64 yqbH S Domain of unknown function (DUF3599)
DFGHHELI_00411 5.4e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
DFGHHELI_00412 3.9e-75 xkdJ
DFGHHELI_00413 2.7e-255 xkdK S Phage tail sheath C-terminal domain
DFGHHELI_00414 6.1e-76 xkdM S Phage tail tube protein
DFGHHELI_00415 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
DFGHHELI_00416 6.2e-265 xkdO L Transglycosylase SLT domain
DFGHHELI_00417 2.7e-118 xkdP S Lysin motif
DFGHHELI_00418 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
DFGHHELI_00419 4.7e-39 xkdR S Protein of unknown function (DUF2577)
DFGHHELI_00420 1.8e-69 xkdS S Protein of unknown function (DUF2634)
DFGHHELI_00421 1.6e-188 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DFGHHELI_00422 6.4e-102 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
DFGHHELI_00423 6.7e-41
DFGHHELI_00424 1.9e-179
DFGHHELI_00425 2.7e-44 xkdW S XkdW protein
DFGHHELI_00426 5.5e-22 xkdX
DFGHHELI_00427 2.8e-154 xepA
DFGHHELI_00428 2.8e-39 xhlA S Haemolysin XhlA
DFGHHELI_00429 9.3e-40 xhlB S SPP1 phage holin
DFGHHELI_00430 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DFGHHELI_00431 6.7e-23 spoIISB S Stage II sporulation protein SB
DFGHHELI_00432 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
DFGHHELI_00433 5.8e-175 pit P phosphate transporter
DFGHHELI_00434 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
DFGHHELI_00435 5.2e-240 steT E amino acid
DFGHHELI_00436 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
DFGHHELI_00438 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DFGHHELI_00439 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DFGHHELI_00441 8.9e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DFGHHELI_00442 1.3e-132 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
DFGHHELI_00443 4.3e-152 dppA E D-aminopeptidase
DFGHHELI_00444 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00445 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DFGHHELI_00446 3.3e-186 dppD P Belongs to the ABC transporter superfamily
DFGHHELI_00447 0.0 dppE E ABC transporter substrate-binding protein
DFGHHELI_00449 1.2e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
DFGHHELI_00450 1.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DFGHHELI_00451 9.7e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DFGHHELI_00452 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
DFGHHELI_00453 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
DFGHHELI_00454 2.2e-159 ykgA E Amidinotransferase
DFGHHELI_00455 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
DFGHHELI_00456 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DFGHHELI_00457 5.5e-09
DFGHHELI_00458 2.3e-128 ykjA S Protein of unknown function (DUF421)
DFGHHELI_00459 2.2e-96 ykkA S Protein of unknown function (DUF664)
DFGHHELI_00460 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DFGHHELI_00461 3.5e-55 ykkC P Multidrug resistance protein
DFGHHELI_00462 7e-50 ykkD P Multidrug resistance protein
DFGHHELI_00463 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
DFGHHELI_00464 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DFGHHELI_00465 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DFGHHELI_00466 1.3e-70 ohrA O Organic hydroperoxide resistance protein
DFGHHELI_00467 9.7e-74 ohrR K COG1846 Transcriptional regulators
DFGHHELI_00468 8.4e-72 ohrB O Organic hydroperoxide resistance protein
DFGHHELI_00469 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
DFGHHELI_00470 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DFGHHELI_00471 2.5e-175 isp O Belongs to the peptidase S8 family
DFGHHELI_00472 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DFGHHELI_00473 1.2e-135 ykoC P Cobalt transport protein
DFGHHELI_00474 5.7e-305 P ABC transporter, ATP-binding protein
DFGHHELI_00475 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
DFGHHELI_00476 1.8e-110 ykoF S YKOF-related Family
DFGHHELI_00477 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_00478 2.4e-240 ykoH 2.7.13.3 T Histidine kinase
DFGHHELI_00479 8.1e-112 ykoI S Peptidase propeptide and YPEB domain
DFGHHELI_00480 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
DFGHHELI_00483 2.2e-222 mgtE P Acts as a magnesium transporter
DFGHHELI_00484 1.4e-53 tnrA K transcriptional
DFGHHELI_00485 5.9e-18
DFGHHELI_00486 6.9e-26 ykoL
DFGHHELI_00487 1.3e-81 mhqR K transcriptional
DFGHHELI_00488 1.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
DFGHHELI_00489 3.7e-99 ykoP G polysaccharide deacetylase
DFGHHELI_00490 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
DFGHHELI_00491 0.0 ykoS
DFGHHELI_00492 4.8e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DFGHHELI_00493 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
DFGHHELI_00494 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DFGHHELI_00495 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
DFGHHELI_00496 1.3e-103 ykoX S membrane-associated protein
DFGHHELI_00497 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
DFGHHELI_00498 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_00499 1.8e-111 rsgI S Anti-sigma factor N-terminus
DFGHHELI_00500 1.9e-26 sspD S small acid-soluble spore protein
DFGHHELI_00501 2.5e-124 ykrK S Domain of unknown function (DUF1836)
DFGHHELI_00502 3.5e-155 htpX O Belongs to the peptidase M48B family
DFGHHELI_00503 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
DFGHHELI_00504 1.2e-10 ydfR S Protein of unknown function (DUF421)
DFGHHELI_00505 4.1e-18 ykzE
DFGHHELI_00506 3.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
DFGHHELI_00507 0.0 kinE 2.7.13.3 T Histidine kinase
DFGHHELI_00508 3.5e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DFGHHELI_00510 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DFGHHELI_00511 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DFGHHELI_00512 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DFGHHELI_00513 2e-230 mtnE 2.6.1.83 E Aminotransferase
DFGHHELI_00514 5.9e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
DFGHHELI_00515 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DFGHHELI_00516 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
DFGHHELI_00517 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DFGHHELI_00518 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
DFGHHELI_00519 7.5e-10 S Spo0E like sporulation regulatory protein
DFGHHELI_00520 2.6e-63 eag
DFGHHELI_00521 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
DFGHHELI_00522 1.3e-75 ykvE K transcriptional
DFGHHELI_00523 2.5e-125 motB N Flagellar motor protein
DFGHHELI_00524 1e-137 motA N flagellar motor
DFGHHELI_00525 0.0 clpE O Belongs to the ClpA ClpB family
DFGHHELI_00526 3.3e-181 ykvI S membrane
DFGHHELI_00527 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DFGHHELI_00528 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
DFGHHELI_00529 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DFGHHELI_00530 5.9e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DFGHHELI_00531 3.4e-61 ykvN K Transcriptional regulator
DFGHHELI_00532 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
DFGHHELI_00533 4.1e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
DFGHHELI_00534 3.5e-35 3.5.1.104 M LysM domain
DFGHHELI_00535 1.5e-161 G Glycosyl hydrolases family 18
DFGHHELI_00536 5.6e-46 ykvR S Protein of unknown function (DUF3219)
DFGHHELI_00537 6e-25 ykvS S protein conserved in bacteria
DFGHHELI_00538 2.8e-28
DFGHHELI_00539 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
DFGHHELI_00540 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_00541 4.9e-90 stoA CO thiol-disulfide
DFGHHELI_00542 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DFGHHELI_00543 6.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
DFGHHELI_00544 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
DFGHHELI_00545 7.6e-128 glcT K antiterminator
DFGHHELI_00546 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_00547 2.1e-39 ptsH G phosphocarrier protein HPr
DFGHHELI_00548 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DFGHHELI_00549 7.2e-39 splA S Transcriptional regulator
DFGHHELI_00550 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
DFGHHELI_00551 1.5e-124 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_00552 4.1e-257 mcpC NT chemotaxis protein
DFGHHELI_00553 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
DFGHHELI_00554 3e-123 ykwD J protein with SCP PR1 domains
DFGHHELI_00555 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
DFGHHELI_00556 0.0 pilS 2.7.13.3 T Histidine kinase
DFGHHELI_00557 7.4e-222 patA 2.6.1.1 E Aminotransferase
DFGHHELI_00558 2.2e-15
DFGHHELI_00559 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
DFGHHELI_00560 4.9e-84 ykyB S YkyB-like protein
DFGHHELI_00561 2.8e-238 ykuC EGP Major facilitator Superfamily
DFGHHELI_00562 1.8e-87 ykuD S protein conserved in bacteria
DFGHHELI_00563 9.4e-166 ykuE S Metallophosphoesterase
DFGHHELI_00564 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_00565 5.2e-234 ykuI T Diguanylate phosphodiesterase
DFGHHELI_00566 3.9e-37 ykuJ S protein conserved in bacteria
DFGHHELI_00567 1.3e-93 ykuK S Ribonuclease H-like
DFGHHELI_00568 3.9e-27 ykzF S Antirepressor AbbA
DFGHHELI_00569 1.6e-76 ykuL S CBS domain
DFGHHELI_00570 3.5e-168 ccpC K Transcriptional regulator
DFGHHELI_00571 1.7e-84 fld C Flavodoxin domain
DFGHHELI_00572 2.6e-174 ykuO
DFGHHELI_00573 8.7e-78 fld C Flavodoxin
DFGHHELI_00574 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DFGHHELI_00575 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DFGHHELI_00576 9e-37 ykuS S Belongs to the UPF0180 family
DFGHHELI_00577 8.8e-142 ykuT M Mechanosensitive ion channel
DFGHHELI_00578 3.9e-101 ykuU O Alkyl hydroperoxide reductase
DFGHHELI_00579 2.4e-80 ykuV CO thiol-disulfide
DFGHHELI_00580 5.8e-95 rok K Repressor of ComK
DFGHHELI_00581 3.5e-145 yknT
DFGHHELI_00582 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DFGHHELI_00583 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DFGHHELI_00584 3.4e-244 moeA 2.10.1.1 H molybdopterin
DFGHHELI_00585 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
DFGHHELI_00586 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
DFGHHELI_00587 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DFGHHELI_00588 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
DFGHHELI_00589 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
DFGHHELI_00590 1.1e-116 yknW S Yip1 domain
DFGHHELI_00591 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DFGHHELI_00592 2.5e-124 macB V ABC transporter, ATP-binding protein
DFGHHELI_00593 3.1e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
DFGHHELI_00594 3.1e-136 fruR K Transcriptional regulator
DFGHHELI_00595 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
DFGHHELI_00596 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
DFGHHELI_00597 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DFGHHELI_00598 8.1e-39 ykoA
DFGHHELI_00599 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DFGHHELI_00600 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DFGHHELI_00601 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
DFGHHELI_00602 1.1e-12 S Uncharacterized protein YkpC
DFGHHELI_00603 1.7e-182 mreB D Rod-share determining protein MreBH
DFGHHELI_00604 1.5e-43 abrB K of stationary sporulation gene expression
DFGHHELI_00605 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
DFGHHELI_00606 5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
DFGHHELI_00607 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
DFGHHELI_00608 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DFGHHELI_00609 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DFGHHELI_00610 8.2e-31 ykzG S Belongs to the UPF0356 family
DFGHHELI_00611 2.1e-146 ykrA S hydrolases of the HAD superfamily
DFGHHELI_00612 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFGHHELI_00614 2.9e-114 recN L Putative cell-wall binding lipoprotein
DFGHHELI_00615 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DFGHHELI_00616 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DFGHHELI_00617 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DFGHHELI_00618 4.1e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DFGHHELI_00619 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
DFGHHELI_00620 1e-276 speA 4.1.1.19 E Arginine
DFGHHELI_00621 1e-41 yktA S Belongs to the UPF0223 family
DFGHHELI_00622 2.1e-117 yktB S Belongs to the UPF0637 family
DFGHHELI_00623 7.1e-26 ykzI
DFGHHELI_00624 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
DFGHHELI_00625 1.7e-76 ykzC S Acetyltransferase (GNAT) family
DFGHHELI_00626 4.6e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DFGHHELI_00627 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
DFGHHELI_00628 0.0 ylaA
DFGHHELI_00629 2.7e-42 ylaB
DFGHHELI_00630 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_00631 7e-12 sigC S Putative zinc-finger
DFGHHELI_00632 2.6e-37 ylaE
DFGHHELI_00633 8.2e-22 S Family of unknown function (DUF5325)
DFGHHELI_00634 0.0 typA T GTP-binding protein TypA
DFGHHELI_00635 4.2e-47 ylaH S YlaH-like protein
DFGHHELI_00636 5.6e-32 ylaI S protein conserved in bacteria
DFGHHELI_00637 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DFGHHELI_00638 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
DFGHHELI_00639 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DFGHHELI_00640 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
DFGHHELI_00641 8.7e-44 ylaN S Belongs to the UPF0358 family
DFGHHELI_00642 2.5e-212 ftsW D Belongs to the SEDS family
DFGHHELI_00643 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DFGHHELI_00644 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
DFGHHELI_00645 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DFGHHELI_00646 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
DFGHHELI_00647 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DFGHHELI_00648 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
DFGHHELI_00649 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
DFGHHELI_00650 3e-167 ctaG S cytochrome c oxidase
DFGHHELI_00651 7e-62 ylbA S YugN-like family
DFGHHELI_00652 2.6e-74 ylbB T COG0517 FOG CBS domain
DFGHHELI_00653 4.8e-199 ylbC S protein with SCP PR1 domains
DFGHHELI_00654 2.2e-61 ylbD S Putative coat protein
DFGHHELI_00655 6.7e-37 ylbE S YlbE-like protein
DFGHHELI_00656 6.8e-75 ylbF S Belongs to the UPF0342 family
DFGHHELI_00657 7.5e-39 ylbG S UPF0298 protein
DFGHHELI_00658 5.6e-95 rsmD 2.1.1.171 L Methyltransferase
DFGHHELI_00659 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DFGHHELI_00660 3.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
DFGHHELI_00661 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
DFGHHELI_00662 2.6e-186 ylbL T Belongs to the peptidase S16 family
DFGHHELI_00663 1.7e-13 yqgA
DFGHHELI_00664 1.8e-122 ylbM S Belongs to the UPF0348 family
DFGHHELI_00666 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
DFGHHELI_00667 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DFGHHELI_00668 7.5e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
DFGHHELI_00669 1.5e-88 ylbP K n-acetyltransferase
DFGHHELI_00670 1.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DFGHHELI_00671 1.8e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DFGHHELI_00672 2.9e-78 mraZ K Belongs to the MraZ family
DFGHHELI_00673 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DFGHHELI_00674 3.7e-44 ftsL D Essential cell division protein
DFGHHELI_00675 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DFGHHELI_00676 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
DFGHHELI_00677 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DFGHHELI_00678 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DFGHHELI_00679 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DFGHHELI_00680 2.8e-185 spoVE D Belongs to the SEDS family
DFGHHELI_00681 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DFGHHELI_00682 5.3e-167 murB 1.3.1.98 M cell wall formation
DFGHHELI_00683 2.2e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DFGHHELI_00684 2.4e-103 ylxW S protein conserved in bacteria
DFGHHELI_00685 1e-102 ylxX S protein conserved in bacteria
DFGHHELI_00686 6.2e-58 sbp S small basic protein
DFGHHELI_00687 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DFGHHELI_00688 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DFGHHELI_00689 0.0 bpr O COG1404 Subtilisin-like serine proteases
DFGHHELI_00690 2.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
DFGHHELI_00691 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_00692 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_00693 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
DFGHHELI_00694 7.1e-250 argE 3.5.1.16 E Acetylornithine deacetylase
DFGHHELI_00695 2.4e-37 ylmC S sporulation protein
DFGHHELI_00696 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
DFGHHELI_00697 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DFGHHELI_00698 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DFGHHELI_00699 1.6e-39 yggT S membrane
DFGHHELI_00700 9.7e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
DFGHHELI_00701 2.6e-67 divIVA D Cell division initiation protein
DFGHHELI_00702 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DFGHHELI_00703 3.8e-63 dksA T COG1734 DnaK suppressor protein
DFGHHELI_00704 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DFGHHELI_00705 1.9e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DFGHHELI_00706 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DFGHHELI_00707 2.6e-231 pyrP F Xanthine uracil
DFGHHELI_00708 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DFGHHELI_00709 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DFGHHELI_00710 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DFGHHELI_00711 0.0 carB 6.3.5.5 F Belongs to the CarB family
DFGHHELI_00712 3.4e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DFGHHELI_00713 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DFGHHELI_00714 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DFGHHELI_00715 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DFGHHELI_00717 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
DFGHHELI_00718 1.4e-179 cysP P phosphate transporter
DFGHHELI_00719 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
DFGHHELI_00720 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
DFGHHELI_00721 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
DFGHHELI_00722 2.1e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
DFGHHELI_00723 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
DFGHHELI_00724 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
DFGHHELI_00725 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
DFGHHELI_00726 2.4e-156 yloC S stress-induced protein
DFGHHELI_00727 1.5e-40 ylzA S Belongs to the UPF0296 family
DFGHHELI_00728 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DFGHHELI_00729 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DFGHHELI_00730 2.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DFGHHELI_00731 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DFGHHELI_00732 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFGHHELI_00733 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DFGHHELI_00734 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DFGHHELI_00735 1e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DFGHHELI_00736 1.6e-140 stp 3.1.3.16 T phosphatase
DFGHHELI_00737 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DFGHHELI_00738 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DFGHHELI_00739 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DFGHHELI_00740 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
DFGHHELI_00741 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DFGHHELI_00742 5.5e-59 asp S protein conserved in bacteria
DFGHHELI_00743 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
DFGHHELI_00744 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
DFGHHELI_00745 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
DFGHHELI_00746 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DFGHHELI_00747 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
DFGHHELI_00748 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DFGHHELI_00749 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DFGHHELI_00750 1.4e-128 IQ reductase
DFGHHELI_00751 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DFGHHELI_00752 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DFGHHELI_00753 0.0 smc D Required for chromosome condensation and partitioning
DFGHHELI_00754 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DFGHHELI_00755 2.9e-87
DFGHHELI_00756 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DFGHHELI_00757 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DFGHHELI_00758 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DFGHHELI_00759 4.5e-36 ylqC S Belongs to the UPF0109 family
DFGHHELI_00760 7e-60 ylqD S YlqD protein
DFGHHELI_00761 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DFGHHELI_00762 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DFGHHELI_00763 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DFGHHELI_00764 6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DFGHHELI_00765 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFGHHELI_00766 6.7e-280 ylqG
DFGHHELI_00767 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
DFGHHELI_00768 9.9e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DFGHHELI_00769 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DFGHHELI_00770 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
DFGHHELI_00771 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DFGHHELI_00772 4.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DFGHHELI_00773 2.5e-169 xerC L tyrosine recombinase XerC
DFGHHELI_00774 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DFGHHELI_00775 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DFGHHELI_00776 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DFGHHELI_00777 6.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
DFGHHELI_00778 2e-74 flgC N Belongs to the flagella basal body rod proteins family
DFGHHELI_00779 1.9e-31 fliE N Flagellar hook-basal body
DFGHHELI_00780 2.6e-254 fliF N The M ring may be actively involved in energy transduction
DFGHHELI_00781 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DFGHHELI_00782 1.1e-104 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
DFGHHELI_00783 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
DFGHHELI_00784 1.5e-69 fliJ N Flagellar biosynthesis chaperone
DFGHHELI_00785 2.2e-36 ylxF S MgtE intracellular N domain
DFGHHELI_00786 4.9e-215 fliK N Flagellar hook-length control protein
DFGHHELI_00787 1.1e-71 flgD N Flagellar basal body rod modification protein
DFGHHELI_00788 1.9e-136 flgG N Flagellar basal body rod
DFGHHELI_00789 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
DFGHHELI_00790 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DFGHHELI_00791 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DFGHHELI_00792 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
DFGHHELI_00793 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
DFGHHELI_00794 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
DFGHHELI_00795 2.2e-36 fliQ N Role in flagellar biosynthesis
DFGHHELI_00796 3.6e-132 fliR N Flagellar biosynthetic protein FliR
DFGHHELI_00797 3.1e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DFGHHELI_00798 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DFGHHELI_00799 7.5e-200 flhF N Flagellar biosynthesis regulator FlhF
DFGHHELI_00800 9.1e-156 flhG D Belongs to the ParA family
DFGHHELI_00801 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
DFGHHELI_00802 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
DFGHHELI_00803 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
DFGHHELI_00804 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
DFGHHELI_00805 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
DFGHHELI_00806 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_00807 1.8e-76 ylxL
DFGHHELI_00808 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
DFGHHELI_00809 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DFGHHELI_00810 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DFGHHELI_00811 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DFGHHELI_00812 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DFGHHELI_00813 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
DFGHHELI_00814 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DFGHHELI_00815 1.7e-232 rasP M zinc metalloprotease
DFGHHELI_00816 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DFGHHELI_00817 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DFGHHELI_00818 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
DFGHHELI_00819 1.1e-203 nusA K Participates in both transcription termination and antitermination
DFGHHELI_00820 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
DFGHHELI_00821 3.1e-47 ylxQ J ribosomal protein
DFGHHELI_00822 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DFGHHELI_00823 3e-44 ylxP S protein conserved in bacteria
DFGHHELI_00824 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DFGHHELI_00825 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DFGHHELI_00826 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DFGHHELI_00827 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DFGHHELI_00828 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DFGHHELI_00829 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
DFGHHELI_00830 4.4e-233 pepR S Belongs to the peptidase M16 family
DFGHHELI_00831 2.6e-42 ymxH S YlmC YmxH family
DFGHHELI_00832 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
DFGHHELI_00833 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
DFGHHELI_00834 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DFGHHELI_00835 8.5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
DFGHHELI_00836 1.5e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DFGHHELI_00837 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DFGHHELI_00838 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
DFGHHELI_00839 4.4e-32 S YlzJ-like protein
DFGHHELI_00840 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DFGHHELI_00841 1.4e-133 ymfC K Transcriptional regulator
DFGHHELI_00842 1.5e-206 ymfD EGP Major facilitator Superfamily
DFGHHELI_00843 7.8e-233 ymfF S Peptidase M16
DFGHHELI_00844 1.1e-239 ymfH S zinc protease
DFGHHELI_00845 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
DFGHHELI_00846 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
DFGHHELI_00847 2.7e-143 ymfK S Protein of unknown function (DUF3388)
DFGHHELI_00848 1.9e-124 ymfM S protein conserved in bacteria
DFGHHELI_00849 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFGHHELI_00850 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
DFGHHELI_00851 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DFGHHELI_00852 3.7e-213 pbpX V Beta-lactamase
DFGHHELI_00853 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
DFGHHELI_00854 1.9e-152 ymdB S protein conserved in bacteria
DFGHHELI_00855 1.2e-36 spoVS S Stage V sporulation protein S
DFGHHELI_00856 8.7e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
DFGHHELI_00857 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DFGHHELI_00858 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DFGHHELI_00859 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
DFGHHELI_00860 2.2e-88 cotE S Spore coat protein
DFGHHELI_00861 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DFGHHELI_00862 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DFGHHELI_00863 5.1e-70 S Regulatory protein YrvL
DFGHHELI_00865 1.8e-96 ymcC S Membrane
DFGHHELI_00866 4.4e-109 pksA K Transcriptional regulator
DFGHHELI_00867 7.2e-129 pksB 3.1.2.6 S Polyketide biosynthesis
DFGHHELI_00868 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DFGHHELI_00869 1.9e-183 pksD Q Acyl transferase domain
DFGHHELI_00870 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
DFGHHELI_00871 1.4e-37 acpK IQ Phosphopantetheine attachment site
DFGHHELI_00872 9.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DFGHHELI_00873 5.1e-245 pksG 2.3.3.10 I synthase
DFGHHELI_00874 5.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
DFGHHELI_00875 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
DFGHHELI_00876 0.0 rhiB IQ polyketide synthase
DFGHHELI_00877 0.0 pfaA Q Polyketide synthase of type I
DFGHHELI_00878 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
DFGHHELI_00879 0.0 dhbF IQ polyketide synthase
DFGHHELI_00880 0.0 pks13 HQ Beta-ketoacyl synthase
DFGHHELI_00881 6.3e-232 cypA C Cytochrome P450
DFGHHELI_00882 4.4e-61 ymzB
DFGHHELI_00883 8.9e-161 ymaE S Metallo-beta-lactamase superfamily
DFGHHELI_00884 8.6e-251 aprX O Belongs to the peptidase S8 family
DFGHHELI_00885 1.9e-07 K Transcriptional regulator
DFGHHELI_00886 4.6e-126 ymaC S Replication protein
DFGHHELI_00887 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
DFGHHELI_00888 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
DFGHHELI_00889 4.1e-50 ebrA P Small Multidrug Resistance protein
DFGHHELI_00891 2.1e-46 ymaF S YmaF family
DFGHHELI_00892 2.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DFGHHELI_00893 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
DFGHHELI_00894 8.2e-23
DFGHHELI_00895 4.5e-22 ymzA
DFGHHELI_00896 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
DFGHHELI_00897 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGHHELI_00898 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGHHELI_00899 2e-109 ymaB
DFGHHELI_00900 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DFGHHELI_00901 1.7e-176 spoVK O stage V sporulation protein K
DFGHHELI_00902 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DFGHHELI_00903 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
DFGHHELI_00904 1.1e-68 glnR K transcriptional
DFGHHELI_00905 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
DFGHHELI_00906 2.6e-132 L Belongs to the 'phage' integrase family
DFGHHELI_00907 2.7e-42 E Zn peptidase
DFGHHELI_00908 5.3e-25 K Helix-turn-helix XRE-family like proteins
DFGHHELI_00911 8.4e-82 S Phage regulatory protein Rha (Phage_pRha)
DFGHHELI_00912 1.3e-10
DFGHHELI_00914 3.4e-98 L DnaD domain protein
DFGHHELI_00915 4.6e-26 S Loader and inhibitor of phage G40P
DFGHHELI_00916 3.3e-170 dnaB 3.6.4.12 L replicative DNA helicase
DFGHHELI_00917 3.2e-22
DFGHHELI_00918 1.5e-18 S Phage-like element PBSX protein XtrA
DFGHHELI_00919 2.8e-07 S Bacillus cereus group antimicrobial protein
DFGHHELI_00920 5.9e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
DFGHHELI_00925 2e-35
DFGHHELI_00926 8.5e-23 cotD S Inner spore coat protein D
DFGHHELI_00929 4.7e-50 V HNH endonuclease
DFGHHELI_00930 3.1e-79 L phage terminase small subunit
DFGHHELI_00931 0.0 S Terminase
DFGHHELI_00932 8.2e-174 S Phage portal protein
DFGHHELI_00933 7.5e-80 S peptidase activity
DFGHHELI_00934 1e-155 gp36 S capsid protein
DFGHHELI_00935 3.8e-20
DFGHHELI_00936 1.7e-37 S Phage gp6-like head-tail connector protein
DFGHHELI_00937 4.7e-38 S Phage head-tail joining protein
DFGHHELI_00938 1.5e-49 S Bacteriophage HK97-gp10, putative tail-component
DFGHHELI_00940 2.4e-78 N Phage major tail protein phi13
DFGHHELI_00943 0.0 D phage tail tape measure protein
DFGHHELI_00944 6.9e-105 S Phage tail protein
DFGHHELI_00945 6.1e-217 NU Prophage endopeptidase tail
DFGHHELI_00946 9.6e-62
DFGHHELI_00949 1.2e-60
DFGHHELI_00950 5e-07
DFGHHELI_00952 1.2e-57 S Bacteriophage holin family
DFGHHELI_00953 3.6e-126 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
DFGHHELI_00954 2.8e-52 S SMI1-KNR4 cell-wall
DFGHHELI_00955 6.9e-288 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DFGHHELI_00956 7.5e-107 S aspartate phosphatase
DFGHHELI_00959 7e-09
DFGHHELI_00960 4.6e-31
DFGHHELI_00961 3.2e-37
DFGHHELI_00962 8.9e-90 G SMI1-KNR4 cell-wall
DFGHHELI_00963 9.6e-141 ynaC
DFGHHELI_00964 8.3e-12 S Protein of unknown function (DUF1433)
DFGHHELI_00965 5.2e-98 ynaD J Acetyltransferase (GNAT) domain
DFGHHELI_00967 2.3e-77 S CAAX protease self-immunity
DFGHHELI_00970 2.7e-82 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
DFGHHELI_00971 2.7e-255 xynT G MFS/sugar transport protein
DFGHHELI_00972 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DFGHHELI_00973 4.3e-214 xylR GK ROK family
DFGHHELI_00974 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DFGHHELI_00975 9.6e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
DFGHHELI_00976 1.3e-111 yokF 3.1.31.1 L RNA catabolic process
DFGHHELI_00977 6.8e-254 iolT EGP Major facilitator Superfamily
DFGHHELI_00978 5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DFGHHELI_00980 1.5e-80 yncE S Protein of unknown function (DUF2691)
DFGHHELI_00981 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
DFGHHELI_00982 5.2e-15
DFGHHELI_00985 1.6e-162 S Thymidylate synthase
DFGHHELI_00987 1.5e-119 S Domain of unknown function, YrpD
DFGHHELI_00990 6.7e-24 tatA U protein secretion
DFGHHELI_00991 1.2e-70
DFGHHELI_00992 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
DFGHHELI_00996 9.3e-281 gerAA EG Spore germination protein
DFGHHELI_00997 2.7e-194 gerAB U Spore germination
DFGHHELI_00998 4.8e-216 gerLC S Spore germination protein
DFGHHELI_00999 3e-150 yndG S DoxX-like family
DFGHHELI_01000 2.7e-114 yndH S Domain of unknown function (DUF4166)
DFGHHELI_01001 4.7e-307 yndJ S YndJ-like protein
DFGHHELI_01003 1.1e-136 yndL S Replication protein
DFGHHELI_01004 5.8e-74 yndM S Protein of unknown function (DUF2512)
DFGHHELI_01005 1.2e-76 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
DFGHHELI_01006 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DFGHHELI_01007 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
DFGHHELI_01008 3.6e-109 yneB L resolvase
DFGHHELI_01009 4.8e-32 ynzC S UPF0291 protein
DFGHHELI_01010 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DFGHHELI_01011 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
DFGHHELI_01012 1.8e-28 yneF S UPF0154 protein
DFGHHELI_01013 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
DFGHHELI_01014 7.8e-126 ccdA O cytochrome c biogenesis protein
DFGHHELI_01015 3.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
DFGHHELI_01016 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
DFGHHELI_01017 4.2e-74 yneK S Protein of unknown function (DUF2621)
DFGHHELI_01018 1.3e-63 hspX O Spore coat protein
DFGHHELI_01019 3.9e-19 sspP S Belongs to the SspP family
DFGHHELI_01020 2.5e-14 sspO S Belongs to the SspO family
DFGHHELI_01021 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DFGHHELI_01022 6.5e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DFGHHELI_01024 3.1e-08 sspN S Small acid-soluble spore protein N family
DFGHHELI_01025 3.9e-35 tlp S Belongs to the Tlp family
DFGHHELI_01026 1.2e-73 yneP S Thioesterase-like superfamily
DFGHHELI_01027 2.2e-53 yneQ
DFGHHELI_01028 4.1e-49 yneR S Belongs to the HesB IscA family
DFGHHELI_01029 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DFGHHELI_01030 6.6e-69 yccU S CoA-binding protein
DFGHHELI_01031 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DFGHHELI_01032 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DFGHHELI_01033 2.3e-12
DFGHHELI_01034 1.3e-57 ynfC
DFGHHELI_01035 5.3e-251 agcS E Sodium alanine symporter
DFGHHELI_01036 5.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
DFGHHELI_01038 4.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
DFGHHELI_01039 8.1e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
DFGHHELI_01040 3.8e-78 yngA S membrane
DFGHHELI_01041 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DFGHHELI_01042 5.5e-104 yngC S membrane-associated protein
DFGHHELI_01043 6.2e-232 nrnB S phosphohydrolase (DHH superfamily)
DFGHHELI_01044 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DFGHHELI_01045 2.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
DFGHHELI_01046 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
DFGHHELI_01047 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
DFGHHELI_01048 6.2e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
DFGHHELI_01049 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DFGHHELI_01050 1.2e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
DFGHHELI_01051 1.5e-302 yngK T Glycosyl hydrolase-like 10
DFGHHELI_01052 4e-63 yngL S Protein of unknown function (DUF1360)
DFGHHELI_01053 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
DFGHHELI_01054 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_01055 8e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_01056 9.8e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
DFGHHELI_01057 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
DFGHHELI_01058 2.3e-246 yoeA V MATE efflux family protein
DFGHHELI_01059 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
DFGHHELI_01061 2.2e-96 L Integrase
DFGHHELI_01062 3e-34 yoeD G Helix-turn-helix domain
DFGHHELI_01063 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
DFGHHELI_01064 1.3e-154 gltR1 K Transcriptional regulator
DFGHHELI_01065 1.2e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
DFGHHELI_01066 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
DFGHHELI_01067 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
DFGHHELI_01068 7.8e-155 gltC K Transcriptional regulator
DFGHHELI_01069 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DFGHHELI_01070 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DFGHHELI_01071 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
DFGHHELI_01072 1.8e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_01073 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
DFGHHELI_01074 1.7e-134 yoxB
DFGHHELI_01075 4.8e-48 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DFGHHELI_01076 2.6e-233 yoaB EGP Major facilitator Superfamily
DFGHHELI_01077 9.7e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
DFGHHELI_01078 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DFGHHELI_01079 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DFGHHELI_01080 1.9e-33 yoaF
DFGHHELI_01081 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
DFGHHELI_01082 1e-12
DFGHHELI_01083 8.2e-37 S Protein of unknown function (DUF4025)
DFGHHELI_01084 1.3e-179 mcpU NT methyl-accepting chemotaxis protein
DFGHHELI_01085 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
DFGHHELI_01086 5e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
DFGHHELI_01087 2.3e-111 yoaK S Membrane
DFGHHELI_01088 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
DFGHHELI_01089 6.6e-130 yoqW S Belongs to the SOS response-associated peptidase family
DFGHHELI_01092 4.4e-213 oxdC 4.1.1.2 G Oxalate decarboxylase
DFGHHELI_01095 8.9e-84
DFGHHELI_01096 7.1e-172 yoaR V vancomycin resistance protein
DFGHHELI_01097 1.2e-74 yoaS S Protein of unknown function (DUF2975)
DFGHHELI_01098 4.4e-30 yozG K Transcriptional regulator
DFGHHELI_01099 8.2e-148 yoaT S Protein of unknown function (DUF817)
DFGHHELI_01100 9.6e-158 yoaU K LysR substrate binding domain
DFGHHELI_01101 3.7e-157 yijE EG EamA-like transporter family
DFGHHELI_01102 9.2e-60 yoaW
DFGHHELI_01103 1.6e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
DFGHHELI_01104 2.9e-165 bla 3.5.2.6 V beta-lactamase
DFGHHELI_01107 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
DFGHHELI_01108 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
DFGHHELI_01109 1.7e-12 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
DFGHHELI_01116 2.5e-116
DFGHHELI_01118 8.3e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
DFGHHELI_01119 3.1e-23 yoqW S Belongs to the SOS response-associated peptidase family
DFGHHELI_01120 6.1e-09 S YolD-like protein
DFGHHELI_01121 6.7e-37
DFGHHELI_01123 9.4e-11 S Domain of unknown function (DUF4879)
DFGHHELI_01124 1.7e-84 S SMI1-KNR4 cell-wall
DFGHHELI_01125 1e-66 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DFGHHELI_01126 7.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
DFGHHELI_01127 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
DFGHHELI_01128 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
DFGHHELI_01129 8.2e-142 yobR 2.3.1.1 J FR47-like protein
DFGHHELI_01130 3e-99 yobS K Transcriptional regulator
DFGHHELI_01131 9.5e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
DFGHHELI_01132 4.3e-83 yobU K Bacterial transcription activator, effector binding domain
DFGHHELI_01133 7.4e-172 yobV K WYL domain
DFGHHELI_01134 2.6e-92 yobW
DFGHHELI_01135 1e-51 czrA K transcriptional
DFGHHELI_01136 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DFGHHELI_01137 1.5e-92 yozB S membrane
DFGHHELI_01138 1.9e-141
DFGHHELI_01139 1.5e-91 yocC
DFGHHELI_01140 1.6e-185 yocD 3.4.17.13 V peptidase S66
DFGHHELI_01141 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
DFGHHELI_01142 7.1e-198 desK 2.7.13.3 T Histidine kinase
DFGHHELI_01143 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_01144 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
DFGHHELI_01145 0.0 recQ 3.6.4.12 L DNA helicase
DFGHHELI_01146 3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DFGHHELI_01147 3.3e-83 dksA T general stress protein
DFGHHELI_01148 6.4e-54 yocL
DFGHHELI_01149 6.2e-32
DFGHHELI_01150 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
DFGHHELI_01151 1.1e-40 yozN
DFGHHELI_01152 1.9e-36 yocN
DFGHHELI_01153 4.2e-56 yozO S Bacterial PH domain
DFGHHELI_01154 2.7e-31 yozC
DFGHHELI_01155 6.8e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
DFGHHELI_01156 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
DFGHHELI_01157 6e-165 sodA 1.15.1.1 P Superoxide dismutase
DFGHHELI_01158 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DFGHHELI_01159 1.1e-167 yocS S -transporter
DFGHHELI_01160 3.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
DFGHHELI_01161 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
DFGHHELI_01162 0.0 yojO P Von Willebrand factor
DFGHHELI_01163 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
DFGHHELI_01164 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DFGHHELI_01165 3.5e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
DFGHHELI_01166 6.5e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
DFGHHELI_01167 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DFGHHELI_01169 1.4e-243 norM V Multidrug efflux pump
DFGHHELI_01170 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DFGHHELI_01171 2.1e-125 yojG S deacetylase
DFGHHELI_01172 2.2e-60 yojF S Protein of unknown function (DUF1806)
DFGHHELI_01173 1.5e-43
DFGHHELI_01174 6.6e-162 rarD S -transporter
DFGHHELI_01175 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
DFGHHELI_01176 3.4e-09
DFGHHELI_01177 5.5e-205 gntP EG COG2610 H gluconate symporter and related permeases
DFGHHELI_01178 8e-64 yodA S tautomerase
DFGHHELI_01179 4.4e-55 yodB K transcriptional
DFGHHELI_01180 4.8e-108 yodC C nitroreductase
DFGHHELI_01181 2.1e-111 mhqD S Carboxylesterase
DFGHHELI_01182 7.1e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
DFGHHELI_01183 6.2e-28 S Protein of unknown function (DUF3311)
DFGHHELI_01184 6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFGHHELI_01185 3.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
DFGHHELI_01186 6.3e-128 yodH Q Methyltransferase
DFGHHELI_01187 1.5e-23 yodI
DFGHHELI_01188 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DFGHHELI_01189 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
DFGHHELI_01190 5.3e-09
DFGHHELI_01191 3.6e-54 yodL S YodL-like
DFGHHELI_01192 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
DFGHHELI_01193 2.8e-24 yozD S YozD-like protein
DFGHHELI_01195 6e-123 yodN
DFGHHELI_01196 1.4e-36 yozE S Belongs to the UPF0346 family
DFGHHELI_01197 2.9e-47 yokU S YokU-like protein, putative antitoxin
DFGHHELI_01198 2.3e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
DFGHHELI_01199 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
DFGHHELI_01200 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
DFGHHELI_01201 2.4e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DFGHHELI_01202 7.9e-123 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DFGHHELI_01203 2.2e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DFGHHELI_01205 8.6e-142 yiiD K acetyltransferase
DFGHHELI_01206 4e-253 cgeD M maturation of the outermost layer of the spore
DFGHHELI_01207 4.5e-38 cgeC
DFGHHELI_01208 8.2e-64 cgeA
DFGHHELI_01209 1.3e-176 cgeB S Spore maturation protein
DFGHHELI_01210 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
DFGHHELI_01211 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
DFGHHELI_01212 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DFGHHELI_01213 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DFGHHELI_01214 1.6e-70 ypoP K transcriptional
DFGHHELI_01215 1.2e-220 mepA V MATE efflux family protein
DFGHHELI_01216 5.5e-29 ypmT S Uncharacterized ympT
DFGHHELI_01217 2.5e-98 ypmS S protein conserved in bacteria
DFGHHELI_01218 1.1e-133 ypmR E GDSL-like Lipase/Acylhydrolase
DFGHHELI_01219 3.7e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
DFGHHELI_01220 8.9e-40 ypmP S Protein of unknown function (DUF2535)
DFGHHELI_01221 1.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DFGHHELI_01222 2e-183 pspF K Transcriptional regulator
DFGHHELI_01223 4.2e-110 hlyIII S protein, Hemolysin III
DFGHHELI_01224 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DFGHHELI_01225 2.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DFGHHELI_01226 4.9e-153 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DFGHHELI_01227 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
DFGHHELI_01228 2.5e-112 ypjP S YpjP-like protein
DFGHHELI_01229 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
DFGHHELI_01230 1.7e-75 yphP S Belongs to the UPF0403 family
DFGHHELI_01231 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DFGHHELI_01232 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
DFGHHELI_01233 7.9e-106 ypgQ S phosphohydrolase
DFGHHELI_01234 1.9e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
DFGHHELI_01235 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DFGHHELI_01237 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
DFGHHELI_01238 7.9e-31 cspD K Cold-shock protein
DFGHHELI_01239 3.8e-16 degR
DFGHHELI_01240 8.1e-31 S Protein of unknown function (DUF2564)
DFGHHELI_01241 3e-29 ypeQ S Zinc-finger
DFGHHELI_01242 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
DFGHHELI_01243 6.6e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DFGHHELI_01244 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
DFGHHELI_01246 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
DFGHHELI_01247 2e-07
DFGHHELI_01248 2.9e-38 ypbS S Protein of unknown function (DUF2533)
DFGHHELI_01249 0.0 ypbR S Dynamin family
DFGHHELI_01250 5.1e-87 ypbQ S protein conserved in bacteria
DFGHHELI_01251 3.5e-205 bcsA Q Naringenin-chalcone synthase
DFGHHELI_01252 1.5e-226 pbuX F xanthine
DFGHHELI_01253 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DFGHHELI_01254 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DFGHHELI_01255 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
DFGHHELI_01256 5e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
DFGHHELI_01257 2.4e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
DFGHHELI_01258 1.5e-186 ptxS K transcriptional
DFGHHELI_01259 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DFGHHELI_01260 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_01261 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
DFGHHELI_01263 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DFGHHELI_01264 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DFGHHELI_01265 2.2e-91 ypsA S Belongs to the UPF0398 family
DFGHHELI_01266 1.6e-235 yprB L RNase_H superfamily
DFGHHELI_01267 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
DFGHHELI_01268 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
DFGHHELI_01269 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
DFGHHELI_01270 1e-47 yppG S YppG-like protein
DFGHHELI_01272 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
DFGHHELI_01275 1.8e-186 yppC S Protein of unknown function (DUF2515)
DFGHHELI_01276 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DFGHHELI_01277 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
DFGHHELI_01278 4.7e-93 ypoC
DFGHHELI_01279 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DFGHHELI_01280 5.7e-129 dnaD L DNA replication protein DnaD
DFGHHELI_01281 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
DFGHHELI_01282 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DFGHHELI_01283 2.2e-79 ypmB S protein conserved in bacteria
DFGHHELI_01284 6.7e-23 ypmA S Protein of unknown function (DUF4264)
DFGHHELI_01285 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DFGHHELI_01286 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DFGHHELI_01287 5.7e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DFGHHELI_01288 1.6e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
DFGHHELI_01289 1.9e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DFGHHELI_01290 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DFGHHELI_01291 2.9e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
DFGHHELI_01292 7.6e-129 bshB1 S proteins, LmbE homologs
DFGHHELI_01293 2.1e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
DFGHHELI_01294 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DFGHHELI_01295 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
DFGHHELI_01296 6.9e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
DFGHHELI_01297 1e-142 ypjB S sporulation protein
DFGHHELI_01298 1.5e-98 ypjA S membrane
DFGHHELI_01299 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
DFGHHELI_01300 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
DFGHHELI_01301 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
DFGHHELI_01302 7.2e-77 ypiF S Protein of unknown function (DUF2487)
DFGHHELI_01303 2.8e-99 ypiB S Belongs to the UPF0302 family
DFGHHELI_01304 5.9e-233 S COG0457 FOG TPR repeat
DFGHHELI_01305 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DFGHHELI_01306 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
DFGHHELI_01307 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DFGHHELI_01308 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DFGHHELI_01309 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DFGHHELI_01310 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
DFGHHELI_01311 3.1e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
DFGHHELI_01312 2.3e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DFGHHELI_01313 6.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DFGHHELI_01314 3.9e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
DFGHHELI_01315 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DFGHHELI_01316 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DFGHHELI_01317 2.5e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
DFGHHELI_01318 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DFGHHELI_01319 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DFGHHELI_01320 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DFGHHELI_01321 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
DFGHHELI_01322 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
DFGHHELI_01323 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
DFGHHELI_01324 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DFGHHELI_01325 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DFGHHELI_01326 1.3e-136 yphF
DFGHHELI_01327 1.2e-18 yphE S Protein of unknown function (DUF2768)
DFGHHELI_01328 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DFGHHELI_01329 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DFGHHELI_01330 1.6e-28 ypzH
DFGHHELI_01331 3.3e-161 seaA S YIEGIA protein
DFGHHELI_01332 3.9e-102 yphA
DFGHHELI_01333 1e-07 S YpzI-like protein
DFGHHELI_01334 8.4e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DFGHHELI_01335 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
DFGHHELI_01336 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DFGHHELI_01337 1.8e-23 S Family of unknown function (DUF5359)
DFGHHELI_01338 5e-111 ypfA M Flagellar protein YcgR
DFGHHELI_01339 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
DFGHHELI_01340 9.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
DFGHHELI_01341 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
DFGHHELI_01342 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
DFGHHELI_01343 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
DFGHHELI_01344 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DFGHHELI_01345 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
DFGHHELI_01346 2.8e-81 ypbF S Protein of unknown function (DUF2663)
DFGHHELI_01347 1.7e-78 ypbE M Lysin motif
DFGHHELI_01348 5.3e-99 ypbD S metal-dependent membrane protease
DFGHHELI_01349 7.8e-285 recQ 3.6.4.12 L DNA helicase
DFGHHELI_01350 5.1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
DFGHHELI_01351 4.7e-41 fer C Ferredoxin
DFGHHELI_01352 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DFGHHELI_01353 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DFGHHELI_01354 2.1e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DFGHHELI_01355 1.3e-196 rsiX
DFGHHELI_01356 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_01357 0.0 resE 2.7.13.3 T Histidine kinase
DFGHHELI_01358 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_01359 2.2e-213 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
DFGHHELI_01360 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
DFGHHELI_01361 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
DFGHHELI_01362 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DFGHHELI_01363 1.9e-87 spmB S Spore maturation protein
DFGHHELI_01364 3.5e-103 spmA S Spore maturation protein
DFGHHELI_01365 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
DFGHHELI_01366 4e-98 ypuI S Protein of unknown function (DUF3907)
DFGHHELI_01367 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DFGHHELI_01368 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DFGHHELI_01369 1.6e-91 ypuF S Domain of unknown function (DUF309)
DFGHHELI_01370 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_01371 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DFGHHELI_01372 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DFGHHELI_01373 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
DFGHHELI_01374 1.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DFGHHELI_01375 7.8e-55 ypuD
DFGHHELI_01376 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DFGHHELI_01377 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
DFGHHELI_01378 2.8e-13 S PAP2 superfamily
DFGHHELI_01379 8.7e-14 eaeH M Domain of Unknown Function (DUF1259)
DFGHHELI_01381 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DFGHHELI_01382 5.6e-07
DFGHHELI_01386 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DFGHHELI_01387 3.6e-149 ypuA S Secreted protein
DFGHHELI_01388 2.6e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DFGHHELI_01389 1.4e-273 spoVAF EG Stage V sporulation protein AF
DFGHHELI_01390 1.4e-110 spoVAEA S stage V sporulation protein
DFGHHELI_01391 2.2e-57 spoVAEB S stage V sporulation protein
DFGHHELI_01392 9e-192 spoVAD I Stage V sporulation protein AD
DFGHHELI_01393 2.3e-78 spoVAC S stage V sporulation protein AC
DFGHHELI_01394 1e-67 spoVAB S Stage V sporulation protein AB
DFGHHELI_01395 3.7e-111 spoVAA S Stage V sporulation protein AA
DFGHHELI_01396 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_01397 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
DFGHHELI_01398 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
DFGHHELI_01399 3.4e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
DFGHHELI_01400 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DFGHHELI_01401 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DFGHHELI_01402 2.6e-166 xerD L recombinase XerD
DFGHHELI_01403 3.7e-37 S Protein of unknown function (DUF4227)
DFGHHELI_01404 2.4e-80 fur P Belongs to the Fur family
DFGHHELI_01405 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
DFGHHELI_01406 3.2e-30 yqkK
DFGHHELI_01407 1.2e-239 mleA 1.1.1.38 C malic enzyme
DFGHHELI_01408 9.1e-235 mleN C Na H antiporter
DFGHHELI_01409 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
DFGHHELI_01410 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
DFGHHELI_01411 4.5e-58 ansR K Transcriptional regulator
DFGHHELI_01412 1.4e-220 yqxK 3.6.4.12 L DNA helicase
DFGHHELI_01413 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
DFGHHELI_01415 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
DFGHHELI_01416 3.1e-12 yqkE S Protein of unknown function (DUF3886)
DFGHHELI_01417 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
DFGHHELI_01418 9.4e-39 yqkC S Protein of unknown function (DUF2552)
DFGHHELI_01419 2.8e-54 yqkB S Belongs to the HesB IscA family
DFGHHELI_01420 8.3e-193 yqkA K GrpB protein
DFGHHELI_01421 7.5e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
DFGHHELI_01422 1.1e-86 yqjY K acetyltransferase
DFGHHELI_01423 2.2e-49 S YolD-like protein
DFGHHELI_01424 2.7e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DFGHHELI_01426 1.3e-224 yqjV G Major Facilitator Superfamily
DFGHHELI_01428 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_01429 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
DFGHHELI_01430 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
DFGHHELI_01431 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_01432 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
DFGHHELI_01433 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DFGHHELI_01434 0.0 rocB E arginine degradation protein
DFGHHELI_01435 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
DFGHHELI_01436 3.6e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DFGHHELI_01437 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DFGHHELI_01438 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DFGHHELI_01439 1.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DFGHHELI_01440 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DFGHHELI_01441 1.4e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DFGHHELI_01442 4.5e-24 yqzJ
DFGHHELI_01443 3.7e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DFGHHELI_01444 2e-137 yqjF S Uncharacterized conserved protein (COG2071)
DFGHHELI_01445 2.8e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
DFGHHELI_01446 2e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DFGHHELI_01447 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
DFGHHELI_01449 2.3e-98 yqjB S protein conserved in bacteria
DFGHHELI_01450 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
DFGHHELI_01451 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DFGHHELI_01452 9e-108 artQ E COG0765 ABC-type amino acid transport system, permease component
DFGHHELI_01453 2.6e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
DFGHHELI_01454 1.2e-76 yqiW S Belongs to the UPF0403 family
DFGHHELI_01455 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DFGHHELI_01456 7.9e-208 norA EGP Major facilitator Superfamily
DFGHHELI_01457 2.6e-152 bmrR K helix_turn_helix, mercury resistance
DFGHHELI_01458 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DFGHHELI_01459 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DFGHHELI_01460 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DFGHHELI_01461 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DFGHHELI_01462 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
DFGHHELI_01463 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
DFGHHELI_01464 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
DFGHHELI_01465 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
DFGHHELI_01466 1.2e-33 yqzF S Protein of unknown function (DUF2627)
DFGHHELI_01467 2.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DFGHHELI_01468 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
DFGHHELI_01469 3.2e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
DFGHHELI_01470 2.8e-210 mmgC I acyl-CoA dehydrogenase
DFGHHELI_01471 8.3e-154 hbdA 1.1.1.157 I Dehydrogenase
DFGHHELI_01472 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
DFGHHELI_01473 2.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DFGHHELI_01474 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
DFGHHELI_01475 6e-27
DFGHHELI_01476 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
DFGHHELI_01478 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
DFGHHELI_01479 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
DFGHHELI_01480 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
DFGHHELI_01481 1.7e-78 argR K Regulates arginine biosynthesis genes
DFGHHELI_01482 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
DFGHHELI_01483 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DFGHHELI_01484 1.3e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DFGHHELI_01485 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFGHHELI_01486 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFGHHELI_01487 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DFGHHELI_01488 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DFGHHELI_01489 2.1e-67 yqhY S protein conserved in bacteria
DFGHHELI_01490 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DFGHHELI_01491 2.6e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DFGHHELI_01492 9.9e-91 spoIIIAH S SpoIIIAH-like protein
DFGHHELI_01493 2.2e-109 spoIIIAG S stage III sporulation protein AG
DFGHHELI_01494 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
DFGHHELI_01495 6.4e-197 spoIIIAE S stage III sporulation protein AE
DFGHHELI_01496 2.3e-58 spoIIIAD S Stage III sporulation protein AD
DFGHHELI_01497 7.6e-29 spoIIIAC S stage III sporulation protein AC
DFGHHELI_01498 1.1e-84 spoIIIAB S Stage III sporulation protein
DFGHHELI_01499 1e-170 spoIIIAA S stage III sporulation protein AA
DFGHHELI_01500 7.9e-37 yqhV S Protein of unknown function (DUF2619)
DFGHHELI_01501 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DFGHHELI_01502 2.2e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
DFGHHELI_01503 3.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DFGHHELI_01504 6.6e-93 yqhR S Conserved membrane protein YqhR
DFGHHELI_01505 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
DFGHHELI_01506 2.2e-61 yqhP
DFGHHELI_01507 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
DFGHHELI_01508 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
DFGHHELI_01509 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
DFGHHELI_01510 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
DFGHHELI_01511 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFGHHELI_01512 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DFGHHELI_01513 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
DFGHHELI_01514 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
DFGHHELI_01515 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
DFGHHELI_01516 1.2e-24 sinI S Anti-repressor SinI
DFGHHELI_01517 1e-54 sinR K transcriptional
DFGHHELI_01518 4.3e-141 tasA S Cell division protein FtsN
DFGHHELI_01519 7.4e-58 sipW 3.4.21.89 U Signal peptidase
DFGHHELI_01520 1.5e-114 yqxM
DFGHHELI_01521 7.3e-54 yqzG S Protein of unknown function (DUF3889)
DFGHHELI_01522 5.2e-26 yqzE S YqzE-like protein
DFGHHELI_01523 8.8e-44 S ComG operon protein 7
DFGHHELI_01524 1.7e-34 comGF U Putative Competence protein ComGF
DFGHHELI_01525 4.1e-59 comGE
DFGHHELI_01526 4.9e-70 gspH NU protein transport across the cell outer membrane
DFGHHELI_01527 3e-47 comGC U Required for transformation and DNA binding
DFGHHELI_01528 6.2e-172 comGB NU COG1459 Type II secretory pathway, component PulF
DFGHHELI_01529 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DFGHHELI_01530 3.6e-174 corA P Mg2 transporter protein
DFGHHELI_01531 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DFGHHELI_01532 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DFGHHELI_01534 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
DFGHHELI_01535 1.8e-37 yqgY S Protein of unknown function (DUF2626)
DFGHHELI_01536 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
DFGHHELI_01537 8.9e-23 yqgW S Protein of unknown function (DUF2759)
DFGHHELI_01538 6.9e-50 yqgV S Thiamine-binding protein
DFGHHELI_01539 5.1e-198 yqgU
DFGHHELI_01540 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
DFGHHELI_01541 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DFGHHELI_01542 5.2e-181 glcK 2.7.1.2 G Glucokinase
DFGHHELI_01543 3.1e-33 yqgQ S Protein conserved in bacteria
DFGHHELI_01544 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
DFGHHELI_01545 2.5e-09 yqgO
DFGHHELI_01546 2.2e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DFGHHELI_01547 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DFGHHELI_01548 8.5e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
DFGHHELI_01550 3.5e-50 yqzD
DFGHHELI_01551 7e-75 yqzC S YceG-like family
DFGHHELI_01552 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DFGHHELI_01553 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DFGHHELI_01554 4.4e-158 pstA P Phosphate transport system permease
DFGHHELI_01555 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
DFGHHELI_01556 5.3e-151 pstS P Phosphate
DFGHHELI_01557 0.0 pbpA 3.4.16.4 M penicillin-binding protein
DFGHHELI_01558 2.5e-231 yqgE EGP Major facilitator superfamily
DFGHHELI_01559 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
DFGHHELI_01560 4e-73 yqgC S protein conserved in bacteria
DFGHHELI_01561 3.9e-131 yqgB S Protein of unknown function (DUF1189)
DFGHHELI_01562 5.2e-47 yqfZ M LysM domain
DFGHHELI_01563 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DFGHHELI_01564 4.3e-62 yqfX S membrane
DFGHHELI_01565 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
DFGHHELI_01566 4.2e-77 zur P Belongs to the Fur family
DFGHHELI_01567 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
DFGHHELI_01568 2.1e-36 yqfT S Protein of unknown function (DUF2624)
DFGHHELI_01569 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DFGHHELI_01570 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DFGHHELI_01571 3.5e-12 yqfQ S YqfQ-like protein
DFGHHELI_01572 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DFGHHELI_01573 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DFGHHELI_01574 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
DFGHHELI_01575 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
DFGHHELI_01576 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DFGHHELI_01577 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DFGHHELI_01578 1.7e-87 yaiI S Belongs to the UPF0178 family
DFGHHELI_01579 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DFGHHELI_01580 4.5e-112 ccpN K CBS domain
DFGHHELI_01581 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DFGHHELI_01582 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DFGHHELI_01583 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
DFGHHELI_01584 8.4e-19 S YqzL-like protein
DFGHHELI_01585 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DFGHHELI_01586 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DFGHHELI_01587 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DFGHHELI_01588 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DFGHHELI_01589 0.0 yqfF S membrane-associated HD superfamily hydrolase
DFGHHELI_01591 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
DFGHHELI_01592 1.9e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
DFGHHELI_01593 2.7e-45 yqfC S sporulation protein YqfC
DFGHHELI_01594 1.9e-23 yqfB
DFGHHELI_01595 4.3e-122 yqfA S UPF0365 protein
DFGHHELI_01596 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
DFGHHELI_01597 2.5e-61 yqeY S Yqey-like protein
DFGHHELI_01598 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DFGHHELI_01599 8.2e-158 yqeW P COG1283 Na phosphate symporter
DFGHHELI_01600 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
DFGHHELI_01601 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DFGHHELI_01602 5.4e-175 prmA J Methylates ribosomal protein L11
DFGHHELI_01603 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DFGHHELI_01604 0.0 dnaK O Heat shock 70 kDa protein
DFGHHELI_01605 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DFGHHELI_01606 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DFGHHELI_01607 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
DFGHHELI_01608 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DFGHHELI_01609 4.7e-52 yqxA S Protein of unknown function (DUF3679)
DFGHHELI_01610 5.8e-222 spoIIP M stage II sporulation protein P
DFGHHELI_01611 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DFGHHELI_01612 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
DFGHHELI_01613 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
DFGHHELI_01614 4.1e-15 S YqzM-like protein
DFGHHELI_01615 0.0 comEC S Competence protein ComEC
DFGHHELI_01616 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
DFGHHELI_01617 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
DFGHHELI_01618 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DFGHHELI_01619 2.9e-139 yqeM Q Methyltransferase
DFGHHELI_01620 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DFGHHELI_01621 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
DFGHHELI_01622 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DFGHHELI_01623 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
DFGHHELI_01624 1.1e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DFGHHELI_01625 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DFGHHELI_01626 5.3e-95 yqeG S hydrolase of the HAD superfamily
DFGHHELI_01628 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
DFGHHELI_01629 4.9e-134 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DFGHHELI_01630 4.8e-103 yqeD S SNARE associated Golgi protein
DFGHHELI_01631 4.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
DFGHHELI_01632 6.3e-131 yqeB
DFGHHELI_01633 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
DFGHHELI_01634 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_01635 1e-35 cisA2 L Recombinase
DFGHHELI_01636 1.3e-257 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DFGHHELI_01637 5e-154 K Transcriptional regulator
DFGHHELI_01638 4e-159 ydhE CG UDP-glucoronosyl and UDP-glucosyl transferase
DFGHHELI_01639 7.2e-72 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
DFGHHELI_01640 2e-205 EGP Major Facilitator Superfamily
DFGHHELI_01641 3.5e-78 P Major Facilitator Superfamily
DFGHHELI_01642 2.6e-170 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DFGHHELI_01643 2.2e-59 mdaB S Flavodoxin-like fold
DFGHHELI_01644 2.3e-79 yvbU K Transcriptional regulator
DFGHHELI_01645 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
DFGHHELI_01648 4.3e-203 S Aspartate phosphatase response regulator
DFGHHELI_01650 2.1e-62
DFGHHELI_01651 4.4e-280 L nucleic acid phosphodiester bond hydrolysis
DFGHHELI_01653 1.5e-29 S SMI1 / KNR4 family
DFGHHELI_01654 3e-22 S SMI1-KNR4 cell-wall
DFGHHELI_01655 2.8e-47
DFGHHELI_01656 4.9e-29
DFGHHELI_01657 4.5e-23 S SMI1-KNR4 cell-wall
DFGHHELI_01658 7.5e-116 EGP Necrosis inducing protein (NPP1)
DFGHHELI_01660 1.5e-155 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
DFGHHELI_01661 2e-89 K Transcriptional regulator PadR-like family
DFGHHELI_01662 2.7e-180 yjlA EG Putative multidrug resistance efflux transporter
DFGHHELI_01663 1.9e-111 K COG1802 Transcriptional regulators
DFGHHELI_01664 1e-110 yrkJ S membrane transporter protein
DFGHHELI_01665 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
DFGHHELI_01666 5.6e-211 yrkH P Rhodanese Homology Domain
DFGHHELI_01668 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
DFGHHELI_01669 1.8e-81 yrkE O DsrE/DsrF/DrsH-like family
DFGHHELI_01670 7.8e-39 yrkD S protein conserved in bacteria
DFGHHELI_01671 4.2e-106 yrkC G Cupin domain
DFGHHELI_01672 1.1e-147 bltR K helix_turn_helix, mercury resistance
DFGHHELI_01673 3.5e-211 blt EGP Major facilitator Superfamily
DFGHHELI_01674 4.5e-82 bltD 2.3.1.57 K FR47-like protein
DFGHHELI_01675 3.9e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
DFGHHELI_01676 3.9e-16 S YrzO-like protein
DFGHHELI_01677 7.1e-170 yrdR EG EamA-like transporter family
DFGHHELI_01678 4.3e-158 yrdQ K Transcriptional regulator
DFGHHELI_01679 1.3e-198 trkA P Oxidoreductase
DFGHHELI_01680 2.5e-156 czcD P COG1230 Co Zn Cd efflux system component
DFGHHELI_01681 5.5e-65 yodA S tautomerase
DFGHHELI_01682 1.5e-161 gltR K LysR substrate binding domain
DFGHHELI_01683 1e-23 C COG2041 Sulfite oxidase and related enzymes
DFGHHELI_01684 3.5e-228 brnQ E Component of the transport system for branched-chain amino acids
DFGHHELI_01685 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
DFGHHELI_01686 1.8e-136 azlC E AzlC protein
DFGHHELI_01687 6.3e-79 bkdR K helix_turn_helix ASNC type
DFGHHELI_01688 8.3e-24 yrdF K ribonuclease inhibitor
DFGHHELI_01689 6e-222 cypA C Cytochrome P450
DFGHHELI_01690 1.4e-34 K Acetyltransferase (GNAT) family
DFGHHELI_01691 8.8e-64 K Transcriptional regulator
DFGHHELI_01692 1.3e-163 scrR K transcriptional
DFGHHELI_01693 3.4e-228 msmE G Bacterial extracellular solute-binding protein
DFGHHELI_01694 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
DFGHHELI_01695 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
DFGHHELI_01696 2.1e-198 rafB P LacY proton/sugar symporter
DFGHHELI_01697 2.7e-253 cscA 3.2.1.26 GH32 G invertase
DFGHHELI_01698 4.6e-148 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
DFGHHELI_01699 7.2e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
DFGHHELI_01701 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
DFGHHELI_01702 2.3e-55 S Protein of unknown function (DUF2568)
DFGHHELI_01703 6.4e-90 yrdA S DinB family
DFGHHELI_01704 1e-164 aadK G Streptomycin adenylyltransferase
DFGHHELI_01705 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
DFGHHELI_01706 6.5e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DFGHHELI_01708 2.8e-123 yrpD S Domain of unknown function, YrpD
DFGHHELI_01709 1.9e-98 flr S Flavin reductase like domain
DFGHHELI_01710 6.1e-117 bmrR K helix_turn_helix, mercury resistance
DFGHHELI_01711 8.1e-49 yjbR S YjbR
DFGHHELI_01712 6.4e-26 epsA I Passenger-associated-transport-repeat
DFGHHELI_01713 3e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
DFGHHELI_01714 3.3e-92 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_01715 1.9e-186 yrpG C Aldo/keto reductase family
DFGHHELI_01716 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
DFGHHELI_01717 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_01718 1.7e-153 S Alpha beta hydrolase
DFGHHELI_01719 4.9e-60 T sh3 domain protein
DFGHHELI_01720 5.4e-61 T sh3 domain protein
DFGHHELI_01721 2.1e-64 E Glyoxalase-like domain
DFGHHELI_01722 1.5e-36 yraG
DFGHHELI_01723 6.4e-63 yraF M Spore coat protein
DFGHHELI_01724 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DFGHHELI_01725 7.5e-26 yraE
DFGHHELI_01726 1.1e-49 yraD M Spore coat protein
DFGHHELI_01727 4.3e-47 yraB K helix_turn_helix, mercury resistance
DFGHHELI_01728 6.2e-25 yphJ 4.1.1.44 S peroxiredoxin activity
DFGHHELI_01729 5.6e-197 adhA 1.1.1.1 C alcohol dehydrogenase
DFGHHELI_01730 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
DFGHHELI_01731 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
DFGHHELI_01732 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
DFGHHELI_01733 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
DFGHHELI_01734 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
DFGHHELI_01735 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
DFGHHELI_01736 0.0 levR K PTS system fructose IIA component
DFGHHELI_01737 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_01738 1.1e-105 yrhP E LysE type translocator
DFGHHELI_01739 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
DFGHHELI_01740 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_01741 7.2e-150 rsiV S Protein of unknown function (DUF3298)
DFGHHELI_01742 0.0 yrhL I Acyltransferase family
DFGHHELI_01743 1.3e-42 yrhK S YrhK-like protein
DFGHHELI_01744 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
DFGHHELI_01745 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
DFGHHELI_01746 3.6e-94 yrhH Q methyltransferase
DFGHHELI_01748 1.8e-142 focA P Formate nitrite
DFGHHELI_01750 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
DFGHHELI_01751 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
DFGHHELI_01752 5.4e-78 yrhD S Protein of unknown function (DUF1641)
DFGHHELI_01753 4.6e-35 yrhC S YrhC-like protein
DFGHHELI_01754 9.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DFGHHELI_01755 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
DFGHHELI_01756 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DFGHHELI_01757 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
DFGHHELI_01758 1e-25 yrzA S Protein of unknown function (DUF2536)
DFGHHELI_01759 4.2e-63 yrrS S Protein of unknown function (DUF1510)
DFGHHELI_01760 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
DFGHHELI_01761 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DFGHHELI_01762 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
DFGHHELI_01763 4.7e-246 yegQ O COG0826 Collagenase and related proteases
DFGHHELI_01764 4.3e-172 yegQ O Peptidase U32
DFGHHELI_01765 3.3e-118 yrrM 2.1.1.104 S O-methyltransferase
DFGHHELI_01766 1.8e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DFGHHELI_01767 1.2e-45 yrzB S Belongs to the UPF0473 family
DFGHHELI_01768 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DFGHHELI_01769 1.7e-41 yrzL S Belongs to the UPF0297 family
DFGHHELI_01770 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DFGHHELI_01771 2.7e-170 yrrI S AI-2E family transporter
DFGHHELI_01772 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DFGHHELI_01773 1.3e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
DFGHHELI_01774 8e-109 gluC P ABC transporter
DFGHHELI_01775 7.6e-107 glnP P ABC transporter
DFGHHELI_01776 8e-08 S Protein of unknown function (DUF3918)
DFGHHELI_01777 9.8e-31 yrzR
DFGHHELI_01778 1.7e-81 yrrD S protein conserved in bacteria
DFGHHELI_01779 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DFGHHELI_01780 1.4e-15 S COG0457 FOG TPR repeat
DFGHHELI_01781 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DFGHHELI_01782 3e-212 iscS 2.8.1.7 E Cysteine desulfurase
DFGHHELI_01783 1.2e-70 cymR K Transcriptional regulator
DFGHHELI_01784 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
DFGHHELI_01785 2e-135 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
DFGHHELI_01786 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DFGHHELI_01787 1.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
DFGHHELI_01789 6.5e-258 lytH 3.5.1.28 M COG3103 SH3 domain protein
DFGHHELI_01790 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DFGHHELI_01791 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DFGHHELI_01792 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DFGHHELI_01793 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DFGHHELI_01794 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
DFGHHELI_01795 8.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
DFGHHELI_01796 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DFGHHELI_01797 1.6e-48 yrzD S Post-transcriptional regulator
DFGHHELI_01798 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_01799 1.2e-112 yrbG S membrane
DFGHHELI_01800 2.2e-73 yrzE S Protein of unknown function (DUF3792)
DFGHHELI_01801 1.1e-38 yajC U Preprotein translocase subunit YajC
DFGHHELI_01802 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DFGHHELI_01803 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DFGHHELI_01804 2.6e-18 yrzS S Protein of unknown function (DUF2905)
DFGHHELI_01805 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DFGHHELI_01806 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DFGHHELI_01807 4.8e-93 bofC S BofC C-terminal domain
DFGHHELI_01808 4.5e-252 csbX EGP Major facilitator Superfamily
DFGHHELI_01809 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
DFGHHELI_01810 6.5e-119 yrzF T serine threonine protein kinase
DFGHHELI_01812 1.3e-50 S Family of unknown function (DUF5412)
DFGHHELI_01813 4.5e-261 alsT E Sodium alanine symporter
DFGHHELI_01814 1e-125 yebC K transcriptional regulatory protein
DFGHHELI_01815 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DFGHHELI_01816 8.3e-157 safA M spore coat assembly protein SafA
DFGHHELI_01817 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DFGHHELI_01818 4.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
DFGHHELI_01819 6.8e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
DFGHHELI_01820 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
DFGHHELI_01821 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
DFGHHELI_01822 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
DFGHHELI_01823 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
DFGHHELI_01824 6.2e-230 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFGHHELI_01825 1.6e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
DFGHHELI_01826 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DFGHHELI_01827 4.1e-56 ysxB J ribosomal protein
DFGHHELI_01828 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DFGHHELI_01829 5.9e-160 spoIVFB S Stage IV sporulation protein
DFGHHELI_01830 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
DFGHHELI_01831 7.3e-144 minD D Belongs to the ParA family
DFGHHELI_01832 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DFGHHELI_01833 1.4e-84 mreD M shape-determining protein
DFGHHELI_01834 1.1e-156 mreC M Involved in formation and maintenance of cell shape
DFGHHELI_01835 1.8e-184 mreB D Rod shape-determining protein MreB
DFGHHELI_01836 5.9e-126 radC E Belongs to the UPF0758 family
DFGHHELI_01837 2.8e-102 maf D septum formation protein Maf
DFGHHELI_01838 3.4e-159 spoIIB S Sporulation related domain
DFGHHELI_01839 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
DFGHHELI_01840 7.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DFGHHELI_01841 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DFGHHELI_01842 1.6e-25
DFGHHELI_01843 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DFGHHELI_01844 6.4e-198 spoVID M stage VI sporulation protein D
DFGHHELI_01845 7.3e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
DFGHHELI_01846 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
DFGHHELI_01847 4.2e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
DFGHHELI_01848 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DFGHHELI_01849 3.6e-146 hemX O cytochrome C
DFGHHELI_01850 5.9e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DFGHHELI_01851 5.4e-89 ysxD
DFGHHELI_01852 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
DFGHHELI_01853 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DFGHHELI_01854 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
DFGHHELI_01855 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DFGHHELI_01856 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DFGHHELI_01857 7.3e-186 ysoA H Tetratricopeptide repeat
DFGHHELI_01858 5.3e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFGHHELI_01859 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFGHHELI_01860 2.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DFGHHELI_01861 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DFGHHELI_01862 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DFGHHELI_01863 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
DFGHHELI_01864 0.0 ilvB 2.2.1.6 E Acetolactate synthase
DFGHHELI_01866 4.8e-76 ysnE K acetyltransferase
DFGHHELI_01867 5.5e-157 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DFGHHELI_01868 1.1e-131 ysnF S protein conserved in bacteria
DFGHHELI_01870 1.5e-91 ysnB S Phosphoesterase
DFGHHELI_01871 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DFGHHELI_01872 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DFGHHELI_01873 5e-196 gerM S COG5401 Spore germination protein
DFGHHELI_01874 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DFGHHELI_01875 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_01876 3.3e-30 gerE K Transcriptional regulator
DFGHHELI_01877 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
DFGHHELI_01878 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
DFGHHELI_01879 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
DFGHHELI_01880 2.4e-107 sdhC C succinate dehydrogenase
DFGHHELI_01881 2e-79 yslB S Protein of unknown function (DUF2507)
DFGHHELI_01882 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
DFGHHELI_01883 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DFGHHELI_01884 2e-52 trxA O Belongs to the thioredoxin family
DFGHHELI_01885 1.2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
DFGHHELI_01887 5.1e-176 etfA C Electron transfer flavoprotein
DFGHHELI_01888 4.5e-135 etfB C Electron transfer flavoprotein
DFGHHELI_01889 2.3e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
DFGHHELI_01890 4e-99 fadR K Transcriptional regulator
DFGHHELI_01891 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DFGHHELI_01892 7.3e-68 yshE S membrane
DFGHHELI_01893 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DFGHHELI_01894 0.0 polX L COG1796 DNA polymerase IV (family X)
DFGHHELI_01895 1.3e-85 cvpA S membrane protein, required for colicin V production
DFGHHELI_01896 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DFGHHELI_01897 2.6e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFGHHELI_01898 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DFGHHELI_01899 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DFGHHELI_01900 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFGHHELI_01901 5.8e-32 sspI S Belongs to the SspI family
DFGHHELI_01902 1e-204 ysfB KT regulator
DFGHHELI_01903 6.1e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
DFGHHELI_01904 4.7e-257 glcF C Glycolate oxidase
DFGHHELI_01905 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
DFGHHELI_01906 0.0 cstA T Carbon starvation protein
DFGHHELI_01907 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
DFGHHELI_01908 3.4e-144 araQ G transport system permease
DFGHHELI_01909 1.4e-167 araP G carbohydrate transport
DFGHHELI_01910 6.2e-254 araN G carbohydrate transport
DFGHHELI_01911 3.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
DFGHHELI_01912 6.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DFGHHELI_01913 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
DFGHHELI_01914 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
DFGHHELI_01915 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DFGHHELI_01916 1.2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
DFGHHELI_01917 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
DFGHHELI_01918 3.5e-67 ysdB S Sigma-w pathway protein YsdB
DFGHHELI_01919 1.4e-43 ysdA S Membrane
DFGHHELI_01920 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DFGHHELI_01921 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DFGHHELI_01922 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DFGHHELI_01924 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DFGHHELI_01925 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DFGHHELI_01926 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
DFGHHELI_01927 0.0 lytS 2.7.13.3 T Histidine kinase
DFGHHELI_01928 2.8e-148 ysaA S HAD-hyrolase-like
DFGHHELI_01929 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DFGHHELI_01931 1.4e-158 ytxC S YtxC-like family
DFGHHELI_01932 7.1e-110 ytxB S SNARE associated Golgi protein
DFGHHELI_01933 3e-173 dnaI L Primosomal protein DnaI
DFGHHELI_01934 4.2e-264 dnaB L Membrane attachment protein
DFGHHELI_01935 2.5e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DFGHHELI_01936 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DFGHHELI_01937 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DFGHHELI_01938 9.9e-67 ytcD K Transcriptional regulator
DFGHHELI_01939 7.1e-204 ytbD EGP Major facilitator Superfamily
DFGHHELI_01940 8.9e-161 ytbE S reductase
DFGHHELI_01941 2.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DFGHHELI_01942 1.5e-107 ytaF P Probably functions as a manganese efflux pump
DFGHHELI_01943 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DFGHHELI_01944 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DFGHHELI_01945 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
DFGHHELI_01946 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_01947 4e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
DFGHHELI_01948 4.1e-242 icd 1.1.1.42 C isocitrate
DFGHHELI_01949 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
DFGHHELI_01950 4.7e-71 yeaL S membrane
DFGHHELI_01951 3.4e-192 ytvI S sporulation integral membrane protein YtvI
DFGHHELI_01952 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
DFGHHELI_01953 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DFGHHELI_01954 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DFGHHELI_01955 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DFGHHELI_01956 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DFGHHELI_01957 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
DFGHHELI_01958 0.0 dnaE 2.7.7.7 L DNA polymerase
DFGHHELI_01959 3.2e-56 ytrH S Sporulation protein YtrH
DFGHHELI_01960 8.2e-69 ytrI
DFGHHELI_01961 9.2e-29
DFGHHELI_01962 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
DFGHHELI_01963 2.4e-47 ytpI S YtpI-like protein
DFGHHELI_01964 8e-241 ytoI K transcriptional regulator containing CBS domains
DFGHHELI_01965 1.9e-156 ytnM S membrane transporter protein
DFGHHELI_01966 4e-234 ytnL 3.5.1.47 E hydrolase activity
DFGHHELI_01967 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
DFGHHELI_01968 9.8e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_01969 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
DFGHHELI_01970 3.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_01971 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DFGHHELI_01972 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
DFGHHELI_01973 3.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
DFGHHELI_01974 1.1e-144 tcyK M Bacterial periplasmic substrate-binding proteins
DFGHHELI_01975 1.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
DFGHHELI_01976 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
DFGHHELI_01977 1.6e-171 ytlI K LysR substrate binding domain
DFGHHELI_01978 1.7e-130 ytkL S Belongs to the UPF0173 family
DFGHHELI_01979 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_01981 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
DFGHHELI_01982 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DFGHHELI_01983 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
DFGHHELI_01984 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DFGHHELI_01985 7.8e-164 ytxK 2.1.1.72 L DNA methylase
DFGHHELI_01986 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DFGHHELI_01987 2.3e-70 ytfJ S Sporulation protein YtfJ
DFGHHELI_01988 5.6e-116 ytfI S Protein of unknown function (DUF2953)
DFGHHELI_01989 3.2e-86 yteJ S RDD family
DFGHHELI_01990 1.8e-179 sppA OU signal peptide peptidase SppA
DFGHHELI_01991 3.7e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DFGHHELI_01992 0.0 ytcJ S amidohydrolase
DFGHHELI_01993 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DFGHHELI_01994 2e-29 sspB S spore protein
DFGHHELI_01995 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DFGHHELI_01996 1.6e-208 iscS2 2.8.1.7 E Cysteine desulfurase
DFGHHELI_01997 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
DFGHHELI_01998 3e-272 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DFGHHELI_01999 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
DFGHHELI_02000 1e-108 yttP K Transcriptional regulator
DFGHHELI_02001 4.5e-88 ytsP 1.8.4.14 T GAF domain-containing protein
DFGHHELI_02002 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
DFGHHELI_02003 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DFGHHELI_02005 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DFGHHELI_02006 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DFGHHELI_02007 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
DFGHHELI_02008 7.9e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
DFGHHELI_02009 6.1e-224 acuC BQ histone deacetylase
DFGHHELI_02010 1.4e-125 motS N Flagellar motor protein
DFGHHELI_02011 2.1e-146 motA N flagellar motor
DFGHHELI_02012 3.8e-182 ccpA K catabolite control protein A
DFGHHELI_02013 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
DFGHHELI_02014 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
DFGHHELI_02015 6.6e-17 ytxH S COG4980 Gas vesicle protein
DFGHHELI_02016 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DFGHHELI_02017 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DFGHHELI_02018 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
DFGHHELI_02019 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DFGHHELI_02020 9.8e-149 ytpQ S Belongs to the UPF0354 family
DFGHHELI_02021 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DFGHHELI_02022 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
DFGHHELI_02023 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
DFGHHELI_02024 1.1e-50 ytzB S small secreted protein
DFGHHELI_02025 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
DFGHHELI_02026 1.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
DFGHHELI_02027 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DFGHHELI_02028 2e-45 ytzH S YtzH-like protein
DFGHHELI_02029 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
DFGHHELI_02030 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFGHHELI_02031 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DFGHHELI_02032 8.5e-165 ytlQ
DFGHHELI_02033 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DFGHHELI_02034 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DFGHHELI_02035 6.6e-270 pepV 3.5.1.18 E Dipeptidase
DFGHHELI_02036 6.1e-225 pbuO S permease
DFGHHELI_02037 4.6e-200 ythQ U Bacterial ABC transporter protein EcsB
DFGHHELI_02038 6.2e-131 ythP V ABC transporter
DFGHHELI_02039 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
DFGHHELI_02040 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DFGHHELI_02041 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_02042 2e-230 ytfP S HI0933-like protein
DFGHHELI_02043 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
DFGHHELI_02044 3.1e-26 yteV S Sporulation protein Cse60
DFGHHELI_02045 5.3e-116 yteU S Integral membrane protein
DFGHHELI_02046 3.7e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
DFGHHELI_02047 1.5e-71 yteS G transport
DFGHHELI_02048 2.6e-216 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
DFGHHELI_02049 1.1e-170 lplB G COG4209 ABC-type polysaccharide transport system, permease component
DFGHHELI_02050 0.0 ytdP K Transcriptional regulator
DFGHHELI_02051 3.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
DFGHHELI_02052 1.3e-143 ytcP G COG0395 ABC-type sugar transport system, permease component
DFGHHELI_02053 3.6e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
DFGHHELI_02054 5.9e-219 bioI 1.14.14.46 C Cytochrome P450
DFGHHELI_02055 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DFGHHELI_02056 9.4e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DFGHHELI_02057 5.7e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DFGHHELI_02058 5.6e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
DFGHHELI_02059 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DFGHHELI_02060 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
DFGHHELI_02061 6.8e-187 msmR K Transcriptional regulator
DFGHHELI_02062 1.4e-242 msmE G Bacterial extracellular solute-binding protein
DFGHHELI_02063 8.2e-168 amyD P ABC transporter
DFGHHELI_02064 9.8e-144 amyC P ABC transporter (permease)
DFGHHELI_02065 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
DFGHHELI_02066 2.1e-51 ytwF P Sulfurtransferase
DFGHHELI_02067 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGHHELI_02068 7.7e-55 ytvB S Protein of unknown function (DUF4257)
DFGHHELI_02069 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
DFGHHELI_02070 1.7e-210 yttB EGP Major facilitator Superfamily
DFGHHELI_02071 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
DFGHHELI_02072 0.0 bceB V ABC transporter (permease)
DFGHHELI_02073 1.1e-138 bceA V ABC transporter, ATP-binding protein
DFGHHELI_02074 6.2e-185 T PhoQ Sensor
DFGHHELI_02075 5.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_02076 4e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
DFGHHELI_02077 7e-127 ytrE V ABC transporter, ATP-binding protein
DFGHHELI_02078 2.8e-142
DFGHHELI_02079 3.2e-149 P ABC-2 family transporter protein
DFGHHELI_02080 4.2e-161 ytrB P abc transporter atp-binding protein
DFGHHELI_02081 5.1e-66 ytrA K GntR family transcriptional regulator
DFGHHELI_02083 6.7e-41 ytzC S Protein of unknown function (DUF2524)
DFGHHELI_02084 1.8e-189 yhcC S Fe-S oxidoreductase
DFGHHELI_02085 2.8e-105 ytqB J Putative rRNA methylase
DFGHHELI_02086 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
DFGHHELI_02087 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
DFGHHELI_02088 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DFGHHELI_02089 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_02090 0.0 asnB 6.3.5.4 E Asparagine synthase
DFGHHELI_02091 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DFGHHELI_02092 9.7e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DFGHHELI_02093 1.2e-38 ytmB S Protein of unknown function (DUF2584)
DFGHHELI_02094 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
DFGHHELI_02095 1.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
DFGHHELI_02096 1.4e-144 ytlC P ABC transporter
DFGHHELI_02097 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DFGHHELI_02098 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
DFGHHELI_02099 1.6e-62 ytkC S Bacteriophage holin family
DFGHHELI_02100 2.1e-76 dps P Belongs to the Dps family
DFGHHELI_02102 2.4e-72 ytkA S YtkA-like
DFGHHELI_02103 8.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DFGHHELI_02104 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
DFGHHELI_02105 6.1e-41 rpmE2 J Ribosomal protein L31
DFGHHELI_02106 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
DFGHHELI_02107 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
DFGHHELI_02108 1.1e-24 S Domain of Unknown Function (DUF1540)
DFGHHELI_02109 4.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
DFGHHELI_02110 8.2e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DFGHHELI_02111 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DFGHHELI_02112 1.3e-165 troA P Belongs to the bacterial solute-binding protein 9 family
DFGHHELI_02113 2.7e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DFGHHELI_02114 5.9e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DFGHHELI_02115 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DFGHHELI_02116 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
DFGHHELI_02117 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DFGHHELI_02118 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
DFGHHELI_02119 4.4e-132 dksA T COG1734 DnaK suppressor protein
DFGHHELI_02120 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
DFGHHELI_02121 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DFGHHELI_02122 4.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
DFGHHELI_02123 4.8e-232 ytcC M Glycosyltransferase Family 4
DFGHHELI_02125 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
DFGHHELI_02126 2.6e-216 cotSA M Glycosyl transferases group 1
DFGHHELI_02127 1.3e-204 cotI S Spore coat protein
DFGHHELI_02128 2.2e-76 tspO T membrane
DFGHHELI_02129 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DFGHHELI_02130 1.8e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
DFGHHELI_02131 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
DFGHHELI_02132 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DFGHHELI_02133 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DFGHHELI_02142 7.8e-08
DFGHHELI_02143 1.3e-09
DFGHHELI_02150 2e-08
DFGHHELI_02155 8.4e-51 mdxE G COG2182 Maltose-binding periplasmic proteins domains
DFGHHELI_02156 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
DFGHHELI_02157 1.1e-172 yvdE K Transcriptional regulator
DFGHHELI_02158 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
DFGHHELI_02159 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
DFGHHELI_02160 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
DFGHHELI_02161 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
DFGHHELI_02162 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DFGHHELI_02163 0.0 yxdM V ABC transporter (permease)
DFGHHELI_02164 5.6e-141 yvcR V ABC transporter, ATP-binding protein
DFGHHELI_02165 2e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DFGHHELI_02166 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_02167 1.5e-32
DFGHHELI_02168 7.5e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
DFGHHELI_02169 1.6e-36 crh G Phosphocarrier protein Chr
DFGHHELI_02170 1.4e-170 whiA K May be required for sporulation
DFGHHELI_02171 2.8e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DFGHHELI_02172 5.7e-166 rapZ S Displays ATPase and GTPase activities
DFGHHELI_02173 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
DFGHHELI_02174 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DFGHHELI_02175 2.5e-91 usp CBM50 M protein conserved in bacteria
DFGHHELI_02176 4.5e-277 S COG0457 FOG TPR repeat
DFGHHELI_02177 0.0 msbA2 3.6.3.44 V ABC transporter
DFGHHELI_02179 6.6e-63
DFGHHELI_02180 2.2e-242
DFGHHELI_02181 1.5e-76
DFGHHELI_02182 9.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
DFGHHELI_02183 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DFGHHELI_02184 1.6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DFGHHELI_02185 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DFGHHELI_02186 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DFGHHELI_02187 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DFGHHELI_02188 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DFGHHELI_02189 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DFGHHELI_02190 4.5e-140 yvpB NU protein conserved in bacteria
DFGHHELI_02191 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
DFGHHELI_02192 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
DFGHHELI_02193 7.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
DFGHHELI_02194 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
DFGHHELI_02195 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DFGHHELI_02196 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DFGHHELI_02197 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DFGHHELI_02198 1.9e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DFGHHELI_02199 1.8e-133 yvoA K transcriptional
DFGHHELI_02200 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
DFGHHELI_02201 1.2e-50 yvlD S Membrane
DFGHHELI_02202 2.6e-26 pspB KT PspC domain
DFGHHELI_02203 9.2e-166 yvlB S Putative adhesin
DFGHHELI_02204 8e-49 yvlA
DFGHHELI_02205 9.6e-33 yvkN
DFGHHELI_02206 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DFGHHELI_02207 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DFGHHELI_02208 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DFGHHELI_02209 1.2e-30 csbA S protein conserved in bacteria
DFGHHELI_02210 0.0 yvkC 2.7.9.2 GT Phosphotransferase
DFGHHELI_02211 1e-99 yvkB K Transcriptional regulator
DFGHHELI_02212 3.3e-226 yvkA EGP Major facilitator Superfamily
DFGHHELI_02213 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DFGHHELI_02214 5.3e-56 swrA S Swarming motility protein
DFGHHELI_02215 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
DFGHHELI_02216 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DFGHHELI_02217 1.6e-123 ftsE D cell division ATP-binding protein FtsE
DFGHHELI_02218 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
DFGHHELI_02219 4.6e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
DFGHHELI_02220 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DFGHHELI_02221 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DFGHHELI_02222 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DFGHHELI_02223 4.6e-51
DFGHHELI_02224 2.5e-08 fliT S bacterial-type flagellum organization
DFGHHELI_02225 6.5e-69 fliS N flagellar protein FliS
DFGHHELI_02226 2.5e-254 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DFGHHELI_02227 1.2e-55 flaG N flagellar protein FlaG
DFGHHELI_02228 9e-81 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DFGHHELI_02229 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DFGHHELI_02230 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DFGHHELI_02231 5.7e-50 yviE
DFGHHELI_02232 7.8e-155 flgL N Belongs to the bacterial flagellin family
DFGHHELI_02233 1.2e-264 flgK N flagellar hook-associated protein
DFGHHELI_02234 4.1e-78 flgN NOU FlgN protein
DFGHHELI_02235 8e-39 flgM KNU Negative regulator of flagellin synthesis
DFGHHELI_02236 7e-74 yvyF S flagellar protein
DFGHHELI_02237 2.6e-80 comFC S Phosphoribosyl transferase domain
DFGHHELI_02238 3.7e-45 comFB S Late competence development protein ComFB
DFGHHELI_02239 6.9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DFGHHELI_02240 6.2e-154 degV S protein conserved in bacteria
DFGHHELI_02241 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_02242 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
DFGHHELI_02243 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
DFGHHELI_02244 5.9e-163 yvhJ K Transcriptional regulator
DFGHHELI_02245 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
DFGHHELI_02246 1.6e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
DFGHHELI_02247 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
DFGHHELI_02248 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
DFGHHELI_02249 2e-261 tuaE M Teichuronic acid biosynthesis protein
DFGHHELI_02250 9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DFGHHELI_02251 2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
DFGHHELI_02252 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_02253 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DFGHHELI_02254 1.1e-94 M Glycosyltransferase like family 2
DFGHHELI_02255 7.7e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DFGHHELI_02256 0.0 lytB 3.5.1.28 D Stage II sporulation protein
DFGHHELI_02257 1e-11
DFGHHELI_02258 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
DFGHHELI_02259 1.9e-214 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DFGHHELI_02260 4.6e-88 M Glycosyltransferase like family 2
DFGHHELI_02261 4.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
DFGHHELI_02262 6.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
DFGHHELI_02263 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DFGHHELI_02264 1.8e-271 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DFGHHELI_02265 5e-132 tagG GM Transport permease protein
DFGHHELI_02266 2.6e-89
DFGHHELI_02267 2.7e-55
DFGHHELI_02268 2.1e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DFGHHELI_02269 2.9e-89 ggaA M Glycosyltransferase like family 2
DFGHHELI_02270 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DFGHHELI_02271 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
DFGHHELI_02272 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DFGHHELI_02273 1.7e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DFGHHELI_02274 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
DFGHHELI_02275 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
DFGHHELI_02276 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DFGHHELI_02277 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DFGHHELI_02278 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DFGHHELI_02279 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
DFGHHELI_02280 1.3e-263 gerBA EG Spore germination protein
DFGHHELI_02281 1.4e-193 gerBB E Spore germination protein
DFGHHELI_02282 5.8e-208 gerAC S Spore germination protein
DFGHHELI_02283 7.8e-247 ywtG EGP Major facilitator Superfamily
DFGHHELI_02284 2.4e-170 ywtF K Transcriptional regulator
DFGHHELI_02285 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
DFGHHELI_02286 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DFGHHELI_02287 3.6e-21 ywtC
DFGHHELI_02288 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
DFGHHELI_02289 8.6e-70 pgsC S biosynthesis protein
DFGHHELI_02290 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
DFGHHELI_02291 5.5e-178 rbsR K transcriptional
DFGHHELI_02292 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DFGHHELI_02293 1.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DFGHHELI_02294 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
DFGHHELI_02295 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
DFGHHELI_02296 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
DFGHHELI_02297 7.3e-92 batE T Sh3 type 3 domain protein
DFGHHELI_02298 8e-48 ywsA S Protein of unknown function (DUF3892)
DFGHHELI_02299 2.8e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
DFGHHELI_02300 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
DFGHHELI_02301 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DFGHHELI_02302 1.1e-169 alsR K LysR substrate binding domain
DFGHHELI_02303 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DFGHHELI_02304 1.1e-124 ywrJ
DFGHHELI_02305 2.6e-123 cotB
DFGHHELI_02306 6.2e-207 cotH M Spore Coat
DFGHHELI_02307 1.3e-12
DFGHHELI_02308 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DFGHHELI_02309 1.1e-53 S Domain of unknown function (DUF4181)
DFGHHELI_02310 3.1e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
DFGHHELI_02311 8e-82 ywrC K Transcriptional regulator
DFGHHELI_02312 7.1e-104 ywrB P Chromate transporter
DFGHHELI_02313 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
DFGHHELI_02315 3.7e-99 ywqN S NAD(P)H-dependent
DFGHHELI_02316 1.4e-161 K Transcriptional regulator
DFGHHELI_02317 1.2e-118 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
DFGHHELI_02318 3.9e-25
DFGHHELI_02319 9.3e-40 S protein secretion by the type VII secretion system
DFGHHELI_02320 6.6e-78 ywqJ S Pre-toxin TG
DFGHHELI_02321 5.2e-17
DFGHHELI_02322 4.7e-43
DFGHHELI_02323 1.7e-212 ywqJ L nucleic acid phosphodiester bond hydrolysis
DFGHHELI_02324 1.1e-38 ywqI S Family of unknown function (DUF5344)
DFGHHELI_02325 1e-19 S Domain of unknown function (DUF5082)
DFGHHELI_02326 6.9e-150 ywqG S Domain of unknown function (DUF1963)
DFGHHELI_02327 2.6e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DFGHHELI_02328 1.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
DFGHHELI_02329 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
DFGHHELI_02330 2e-116 ywqC M biosynthesis protein
DFGHHELI_02331 1.2e-17
DFGHHELI_02332 2.3e-306 ywqB S SWIM zinc finger
DFGHHELI_02333 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
DFGHHELI_02334 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
DFGHHELI_02335 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
DFGHHELI_02336 3.7e-57 ssbB L Single-stranded DNA-binding protein
DFGHHELI_02337 3.8e-66 ywpG
DFGHHELI_02338 1.1e-66 ywpF S YwpF-like protein
DFGHHELI_02339 5.2e-50 srtA 3.4.22.70 M Sortase family
DFGHHELI_02340 9.8e-147 ywpD T Histidine kinase
DFGHHELI_02341 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DFGHHELI_02342 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DFGHHELI_02343 2.6e-197 S aspartate phosphatase
DFGHHELI_02344 3.7e-140 flhP N flagellar basal body
DFGHHELI_02345 1.3e-124 flhO N flagellar basal body
DFGHHELI_02346 3.5e-180 mbl D Rod shape-determining protein
DFGHHELI_02347 3e-44 spoIIID K Stage III sporulation protein D
DFGHHELI_02348 2.1e-70 ywoH K COG1846 Transcriptional regulators
DFGHHELI_02349 2.7e-211 ywoG EGP Major facilitator Superfamily
DFGHHELI_02351 3.4e-229 ywoF P Right handed beta helix region
DFGHHELI_02352 1.3e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
DFGHHELI_02353 9.1e-240 ywoD EGP Major facilitator superfamily
DFGHHELI_02354 6.8e-104 phzA Q Isochorismatase family
DFGHHELI_02355 1.2e-77
DFGHHELI_02356 3.3e-225 amt P Ammonium transporter
DFGHHELI_02357 1.6e-58 nrgB K Belongs to the P(II) protein family
DFGHHELI_02358 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
DFGHHELI_02359 3e-72 ywnJ S VanZ like family
DFGHHELI_02360 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
DFGHHELI_02361 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
DFGHHELI_02362 8.9e-10 ywnC S Family of unknown function (DUF5362)
DFGHHELI_02363 2.2e-70 ywnF S Family of unknown function (DUF5392)
DFGHHELI_02364 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DFGHHELI_02365 5e-142 mta K transcriptional
DFGHHELI_02366 2.6e-59 ywnC S Family of unknown function (DUF5362)
DFGHHELI_02367 3.1e-113 ywnB S NAD(P)H-binding
DFGHHELI_02368 1.7e-64 ywnA K Transcriptional regulator
DFGHHELI_02369 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DFGHHELI_02370 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
DFGHHELI_02371 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
DFGHHELI_02372 2.8e-08 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
DFGHHELI_02373 3.8e-11 csbD K CsbD-like
DFGHHELI_02374 3e-84 ywmF S Peptidase M50
DFGHHELI_02375 2.3e-103 S response regulator aspartate phosphatase
DFGHHELI_02376 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DFGHHELI_02377 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DFGHHELI_02379 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
DFGHHELI_02380 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
DFGHHELI_02381 9.2e-176 spoIID D Stage II sporulation protein D
DFGHHELI_02382 1.4e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DFGHHELI_02383 1.9e-130 ywmB S TATA-box binding
DFGHHELI_02384 2.1e-32 ywzB S membrane
DFGHHELI_02385 1.1e-86 ywmA
DFGHHELI_02386 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DFGHHELI_02387 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DFGHHELI_02388 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DFGHHELI_02389 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DFGHHELI_02390 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFGHHELI_02391 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DFGHHELI_02392 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFGHHELI_02393 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
DFGHHELI_02394 5.6e-62 atpI S ATP synthase
DFGHHELI_02395 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DFGHHELI_02396 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DFGHHELI_02397 7.2e-95 ywlG S Belongs to the UPF0340 family
DFGHHELI_02398 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
DFGHHELI_02399 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DFGHHELI_02400 1.7e-91 mntP P Probably functions as a manganese efflux pump
DFGHHELI_02401 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DFGHHELI_02402 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
DFGHHELI_02403 6.1e-112 spoIIR S stage II sporulation protein R
DFGHHELI_02404 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
DFGHHELI_02406 2.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DFGHHELI_02407 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DFGHHELI_02408 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_02409 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
DFGHHELI_02410 8.6e-160 ywkB S Membrane transport protein
DFGHHELI_02411 0.0 sfcA 1.1.1.38 C malic enzyme
DFGHHELI_02412 7e-104 tdk 2.7.1.21 F thymidine kinase
DFGHHELI_02413 1.1e-32 rpmE J Binds the 23S rRNA
DFGHHELI_02414 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DFGHHELI_02415 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
DFGHHELI_02416 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DFGHHELI_02417 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DFGHHELI_02418 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
DFGHHELI_02419 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
DFGHHELI_02420 1.8e-90 ywjG S Domain of unknown function (DUF2529)
DFGHHELI_02421 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DFGHHELI_02422 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DFGHHELI_02423 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
DFGHHELI_02424 0.0 fadF C COG0247 Fe-S oxidoreductase
DFGHHELI_02425 8.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
DFGHHELI_02426 2.8e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
DFGHHELI_02427 2.7e-42 ywjC
DFGHHELI_02428 1.1e-95 ywjB H RibD C-terminal domain
DFGHHELI_02429 0.0 ywjA V ABC transporter
DFGHHELI_02430 1e-284 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DFGHHELI_02431 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
DFGHHELI_02432 3.6e-94 narJ 1.7.5.1 C nitrate reductase
DFGHHELI_02433 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
DFGHHELI_02434 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DFGHHELI_02435 7e-86 arfM T cyclic nucleotide binding
DFGHHELI_02436 1.7e-139 ywiC S YwiC-like protein
DFGHHELI_02437 5.9e-129 fnr K helix_turn_helix, cAMP Regulatory protein
DFGHHELI_02438 2.3e-213 narK P COG2223 Nitrate nitrite transporter
DFGHHELI_02439 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DFGHHELI_02440 4.7e-73 ywiB S protein conserved in bacteria
DFGHHELI_02441 1e-07 S Bacteriocin subtilosin A
DFGHHELI_02442 6.4e-270 C Fe-S oxidoreductases
DFGHHELI_02444 3.3e-132 cbiO V ABC transporter
DFGHHELI_02445 1.9e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
DFGHHELI_02446 3.4e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
DFGHHELI_02447 2.9e-248 L Peptidase, M16
DFGHHELI_02449 1.1e-245 ywhL CO amine dehydrogenase activity
DFGHHELI_02450 2.7e-191 ywhK CO amine dehydrogenase activity
DFGHHELI_02451 7.5e-86 S aspartate phosphatase
DFGHHELI_02453 1.4e-27 ywhH S Aminoacyl-tRNA editing domain
DFGHHELI_02454 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
DFGHHELI_02455 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DFGHHELI_02456 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DFGHHELI_02457 3.6e-49
DFGHHELI_02458 8.9e-95 ywhD S YwhD family
DFGHHELI_02459 3.3e-118 ywhC S Peptidase family M50
DFGHHELI_02460 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
DFGHHELI_02461 3.3e-71 ywhA K Transcriptional regulator
DFGHHELI_02462 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DFGHHELI_02464 6.1e-239 mmr U Major Facilitator Superfamily
DFGHHELI_02465 2.4e-78 yffB K Transcriptional regulator
DFGHHELI_02466 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
DFGHHELI_02467 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
DFGHHELI_02468 3.1e-36 ywzC S Belongs to the UPF0741 family
DFGHHELI_02469 5.1e-110 rsfA_1
DFGHHELI_02470 1.3e-157 ywfM EG EamA-like transporter family
DFGHHELI_02471 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
DFGHHELI_02472 2.4e-156 cysL K Transcriptional regulator
DFGHHELI_02473 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
DFGHHELI_02474 1.3e-145 ywfI C May function as heme-dependent peroxidase
DFGHHELI_02475 6.4e-137 IQ Enoyl-(Acyl carrier protein) reductase
DFGHHELI_02476 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
DFGHHELI_02477 1.9e-209 bacE EGP Major facilitator Superfamily
DFGHHELI_02478 4e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
DFGHHELI_02479 4.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_02480 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
DFGHHELI_02481 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
DFGHHELI_02482 7.8e-206 ywfA EGP Major facilitator Superfamily
DFGHHELI_02483 1.4e-248 lysP E amino acid
DFGHHELI_02484 0.0 rocB E arginine degradation protein
DFGHHELI_02485 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
DFGHHELI_02486 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
DFGHHELI_02487 1.2e-77
DFGHHELI_02488 1.3e-86 spsL 5.1.3.13 M Spore Coat
DFGHHELI_02489 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DFGHHELI_02490 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DFGHHELI_02491 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DFGHHELI_02492 7.9e-188 spsG M Spore Coat
DFGHHELI_02493 9.7e-132 spsF M Spore Coat
DFGHHELI_02494 3.5e-213 spsE 2.5.1.56 M acid synthase
DFGHHELI_02495 4e-164 spsD 2.3.1.210 K Spore Coat
DFGHHELI_02496 7.9e-224 spsC E Belongs to the DegT DnrJ EryC1 family
DFGHHELI_02497 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
DFGHHELI_02498 3.4e-143 spsA M Spore Coat
DFGHHELI_02499 6.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
DFGHHELI_02500 4.3e-59 ywdK S small membrane protein
DFGHHELI_02501 3.7e-238 ywdJ F Xanthine uracil
DFGHHELI_02502 7.7e-49 ywdI S Family of unknown function (DUF5327)
DFGHHELI_02503 5.9e-255 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
DFGHHELI_02504 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DFGHHELI_02505 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
DFGHHELI_02506 1.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DFGHHELI_02507 2e-28 ywdA
DFGHHELI_02508 3.1e-286 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
DFGHHELI_02509 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_02510 2e-138 focA P Formate/nitrite transporter
DFGHHELI_02511 3.5e-149 sacT K transcriptional antiterminator
DFGHHELI_02513 0.0 vpr O Belongs to the peptidase S8 family
DFGHHELI_02514 6.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_02515 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
DFGHHELI_02516 1.5e-201 rodA D Belongs to the SEDS family
DFGHHELI_02517 2.3e-204 S Acetyltransferase
DFGHHELI_02518 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
DFGHHELI_02519 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
DFGHHELI_02520 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
DFGHHELI_02521 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DFGHHELI_02522 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
DFGHHELI_02523 1e-35 ywzA S membrane
DFGHHELI_02524 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DFGHHELI_02525 2.6e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DFGHHELI_02526 9.5e-60 gtcA S GtrA-like protein
DFGHHELI_02527 2.2e-122 ywcC K transcriptional regulator
DFGHHELI_02529 9.8e-49 ywcB S Protein of unknown function, DUF485
DFGHHELI_02530 2.2e-266 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFGHHELI_02531 8.7e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
DFGHHELI_02532 4.2e-223 ywbN P Dyp-type peroxidase family protein
DFGHHELI_02533 1.2e-184 ycdO P periplasmic lipoprotein involved in iron transport
DFGHHELI_02534 3.9e-249 P COG0672 High-affinity Fe2 Pb2 permease
DFGHHELI_02535 1.1e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DFGHHELI_02536 9e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DFGHHELI_02537 1.6e-152 ywbI K Transcriptional regulator
DFGHHELI_02538 1.1e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
DFGHHELI_02539 5.8e-110 ywbG M effector of murein hydrolase
DFGHHELI_02540 3.1e-207 ywbF EGP Major facilitator Superfamily
DFGHHELI_02541 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
DFGHHELI_02542 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
DFGHHELI_02543 2.2e-66 ywbC 4.4.1.5 E glyoxalase
DFGHHELI_02544 5.9e-72 E LysE type translocator
DFGHHELI_02545 6.8e-75 S YqcI/YcgG family
DFGHHELI_02546 2.1e-107 ywbB S Protein of unknown function (DUF2711)
DFGHHELI_02547 2.3e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DFGHHELI_02548 6.6e-268 epr 3.4.21.62 O Belongs to the peptidase S8 family
DFGHHELI_02549 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_02550 4e-153 sacY K transcriptional antiterminator
DFGHHELI_02551 4.5e-168 gspA M General stress
DFGHHELI_02552 3.3e-124 ywaF S Integral membrane protein
DFGHHELI_02553 4e-87 ywaE K Transcriptional regulator
DFGHHELI_02554 5e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DFGHHELI_02555 8.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
DFGHHELI_02556 5.3e-92 K Helix-turn-helix XRE-family like proteins
DFGHHELI_02557 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
DFGHHELI_02558 5.2e-130 ynfM EGP Major facilitator Superfamily
DFGHHELI_02559 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
DFGHHELI_02560 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DFGHHELI_02561 2.5e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_02562 1.2e-232 dltB M membrane protein involved in D-alanine export
DFGHHELI_02563 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_02564 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DFGHHELI_02565 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_02566 2.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DFGHHELI_02567 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DFGHHELI_02568 7.3e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
DFGHHELI_02569 5.9e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DFGHHELI_02570 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
DFGHHELI_02571 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
DFGHHELI_02572 1.1e-19 yxzF
DFGHHELI_02573 1.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DFGHHELI_02574 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
DFGHHELI_02575 4.6e-211 yxlH EGP Major facilitator Superfamily
DFGHHELI_02576 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DFGHHELI_02577 6.3e-165 yxlF V ABC transporter, ATP-binding protein
DFGHHELI_02578 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
DFGHHELI_02579 4.9e-28
DFGHHELI_02580 2.4e-45 yxlC S Family of unknown function (DUF5345)
DFGHHELI_02581 1.7e-88 sigY K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_02582 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
DFGHHELI_02583 8.2e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DFGHHELI_02584 0.0 cydD V ATP-binding protein
DFGHHELI_02585 1e-309 cydD V ATP-binding
DFGHHELI_02586 3.8e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
DFGHHELI_02587 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
DFGHHELI_02588 2.1e-228 cimH C COG3493 Na citrate symporter
DFGHHELI_02589 8.8e-309 3.4.24.84 O Peptidase family M48
DFGHHELI_02591 4.7e-154 yxkH G Polysaccharide deacetylase
DFGHHELI_02592 5.9e-205 msmK P Belongs to the ABC transporter superfamily
DFGHHELI_02593 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
DFGHHELI_02594 7.4e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DFGHHELI_02595 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DFGHHELI_02596 1.4e-73 yxkC S Domain of unknown function (DUF4352)
DFGHHELI_02597 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DFGHHELI_02598 5.9e-77 S Protein of unknown function (DUF1453)
DFGHHELI_02599 8.3e-192 yxjM T Signal transduction histidine kinase
DFGHHELI_02600 3.4e-115 K helix_turn_helix, Lux Regulon
DFGHHELI_02601 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DFGHHELI_02604 2.3e-84 yxjI S LURP-one-related
DFGHHELI_02605 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
DFGHHELI_02606 1.5e-216 yxjG 2.1.1.14 E Methionine synthase
DFGHHELI_02607 3.5e-135 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
DFGHHELI_02608 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DFGHHELI_02609 5.3e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DFGHHELI_02610 4.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
DFGHHELI_02611 2.7e-157 rlmA 2.1.1.187 Q Methyltransferase domain
DFGHHELI_02612 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DFGHHELI_02613 2.7e-104 T Domain of unknown function (DUF4163)
DFGHHELI_02614 3e-47 yxiS
DFGHHELI_02615 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
DFGHHELI_02616 6.6e-224 citH C Citrate transporter
DFGHHELI_02617 3.3e-143 exoK GH16 M licheninase activity
DFGHHELI_02618 8.3e-151 licT K transcriptional antiterminator
DFGHHELI_02619 6.8e-111
DFGHHELI_02620 3.6e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
DFGHHELI_02621 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
DFGHHELI_02622 1.2e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
DFGHHELI_02623 7.8e-55 padR K Transcriptional regulator PadR-like family
DFGHHELI_02624 6.5e-61 S Protein of unknown function (DUF2812)
DFGHHELI_02627 7.3e-41 yxiJ S YxiJ-like protein
DFGHHELI_02628 8.7e-84 yxiI S Protein of unknown function (DUF2716)
DFGHHELI_02629 1.5e-164 yxxF EG EamA-like transporter family
DFGHHELI_02630 6.3e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_02631 9.3e-122 1.14.11.45 E 2OG-Fe dioxygenase
DFGHHELI_02632 5.4e-72 yxiE T Belongs to the universal stress protein A family
DFGHHELI_02633 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DFGHHELI_02634 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_02635 5.5e-53
DFGHHELI_02636 2.1e-214 S nuclease activity
DFGHHELI_02637 2.3e-38 yxiC S Family of unknown function (DUF5344)
DFGHHELI_02638 1e-20 S Domain of unknown function (DUF5082)
DFGHHELI_02639 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DFGHHELI_02640 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
DFGHHELI_02641 1.7e-96 S GTP binding
DFGHHELI_02642 4.9e-77 L NgoFVII restriction endonuclease
DFGHHELI_02643 1.6e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
DFGHHELI_02644 9.4e-10 S Oxidoreductase
DFGHHELI_02646 4.2e-13 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
DFGHHELI_02647 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
DFGHHELI_02648 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
DFGHHELI_02649 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DFGHHELI_02650 4.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
DFGHHELI_02651 3.7e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
DFGHHELI_02652 1.2e-250 lysP E amino acid
DFGHHELI_02653 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
DFGHHELI_02654 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DFGHHELI_02655 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DFGHHELI_02656 3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DFGHHELI_02657 2e-152 yxxB S Domain of Unknown Function (DUF1206)
DFGHHELI_02658 4.3e-195 eutH E Ethanolamine utilisation protein, EutH
DFGHHELI_02659 1e-251 yxeQ S MmgE/PrpD family
DFGHHELI_02660 1.2e-213 yxeP 3.5.1.47 E hydrolase activity
DFGHHELI_02661 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
DFGHHELI_02662 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
DFGHHELI_02663 7.9e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
DFGHHELI_02664 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_02665 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_02666 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
DFGHHELI_02667 1.5e-149 yidA S hydrolases of the HAD superfamily
DFGHHELI_02670 1.3e-20 yxeE
DFGHHELI_02671 5.6e-16 yxeD
DFGHHELI_02672 8.5e-69
DFGHHELI_02673 1.1e-175 fhuD P ABC transporter
DFGHHELI_02674 5.9e-58 yxeA S Protein of unknown function (DUF1093)
DFGHHELI_02675 0.0 yxdM V ABC transporter (permease)
DFGHHELI_02676 3.7e-137 yxdL V ABC transporter, ATP-binding protein
DFGHHELI_02677 1e-179 T PhoQ Sensor
DFGHHELI_02678 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_02679 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
DFGHHELI_02680 1.9e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
DFGHHELI_02681 3e-167 iolH G Xylose isomerase-like TIM barrel
DFGHHELI_02682 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
DFGHHELI_02683 9.6e-234 iolF EGP Major facilitator Superfamily
DFGHHELI_02684 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
DFGHHELI_02685 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
DFGHHELI_02686 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
DFGHHELI_02687 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
DFGHHELI_02688 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DFGHHELI_02689 7.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
DFGHHELI_02690 4.1e-175 iolS C Aldo keto reductase
DFGHHELI_02692 8.3e-48 yxcD S Protein of unknown function (DUF2653)
DFGHHELI_02693 2.5e-90 S CGNR zinc finger
DFGHHELI_02694 8.9e-79 T HPP family
DFGHHELI_02695 1.5e-245 csbC EGP Major facilitator Superfamily
DFGHHELI_02696 0.0 htpG O Molecular chaperone. Has ATPase activity
DFGHHELI_02698 1.3e-151 IQ Enoyl-(Acyl carrier protein) reductase
DFGHHELI_02699 1e-199 yxbF K Bacterial regulatory proteins, tetR family
DFGHHELI_02700 3.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
DFGHHELI_02701 4.5e-24 yxaI S membrane protein domain
DFGHHELI_02702 1.1e-90 S PQQ-like domain
DFGHHELI_02703 1.4e-61 S Family of unknown function (DUF5391)
DFGHHELI_02704 1.4e-75 yxaI S membrane protein domain
DFGHHELI_02705 2.5e-225 P Protein of unknown function (DUF418)
DFGHHELI_02706 5.1e-195 yxaG 1.13.11.24 S AraC-like ligand binding domain
DFGHHELI_02707 2.1e-100 yxaF K Transcriptional regulator
DFGHHELI_02708 2.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_02709 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_02710 5.2e-50 S LrgA family
DFGHHELI_02711 1.3e-117 yxaC M effector of murein hydrolase
DFGHHELI_02712 3.6e-188 yxaB GM Polysaccharide pyruvyl transferase
DFGHHELI_02713 1.9e-185 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DFGHHELI_02714 1.3e-123 gntR K transcriptional
DFGHHELI_02715 1.4e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
DFGHHELI_02716 6.1e-228 gntP EG COG2610 H gluconate symporter and related permeases
DFGHHELI_02717 5.1e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DFGHHELI_02718 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
DFGHHELI_02719 2.8e-285 ahpF O Alkyl hydroperoxide reductase
DFGHHELI_02720 1.1e-189 wgaE S Polysaccharide pyruvyl transferase
DFGHHELI_02721 2.8e-287 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DFGHHELI_02722 1e-263 bglF G phosphotransferase system
DFGHHELI_02723 2.4e-31 bglF G phosphotransferase system
DFGHHELI_02724 8.1e-123 yydK K Transcriptional regulator
DFGHHELI_02725 7.4e-206 I acetylesterase activity
DFGHHELI_02726 1.2e-108 S ABC-2 family transporter protein
DFGHHELI_02727 1.7e-100 prrC P ABC transporter
DFGHHELI_02728 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
DFGHHELI_02729 7.2e-222
DFGHHELI_02730 7.4e-145 U Protein of unknown function DUF262
DFGHHELI_02731 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DFGHHELI_02732 1.1e-09 S YyzF-like protein
DFGHHELI_02733 3.2e-63
DFGHHELI_02734 8.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DFGHHELI_02736 2.6e-31 yycQ S Protein of unknown function (DUF2651)
DFGHHELI_02737 3.2e-209 yycP
DFGHHELI_02738 1.2e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DFGHHELI_02739 4.5e-85 yycN 2.3.1.128 K Acetyltransferase
DFGHHELI_02740 1.1e-187 S aspartate phosphatase
DFGHHELI_02742 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
DFGHHELI_02743 7.2e-256 rocE E amino acid
DFGHHELI_02744 4.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
DFGHHELI_02745 7.4e-16
DFGHHELI_02746 1.6e-94
DFGHHELI_02747 2.3e-24 S Sporulation delaying protein SdpA
DFGHHELI_02748 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
DFGHHELI_02749 1.2e-40 sdpR K transcriptional
DFGHHELI_02751 1.3e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
DFGHHELI_02752 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
DFGHHELI_02753 1.5e-94 K PFAM response regulator receiver
DFGHHELI_02754 5.2e-74 S Peptidase propeptide and YPEB domain
DFGHHELI_02755 2.5e-17 S Peptidase propeptide and YPEB domain
DFGHHELI_02756 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DFGHHELI_02757 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
DFGHHELI_02758 1.8e-153 yycI S protein conserved in bacteria
DFGHHELI_02759 1.9e-256 yycH S protein conserved in bacteria
DFGHHELI_02760 0.0 vicK 2.7.13.3 T Histidine kinase
DFGHHELI_02761 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_02766 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DFGHHELI_02767 4.9e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_02768 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DFGHHELI_02769 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
DFGHHELI_02771 1.9e-15 yycC K YycC-like protein
DFGHHELI_02772 7.1e-220 yeaN P COG2807 Cyanate permease
DFGHHELI_02773 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DFGHHELI_02774 4.9e-73 rplI J binds to the 23S rRNA
DFGHHELI_02775 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DFGHHELI_02776 1.1e-159 yybS S membrane
DFGHHELI_02778 3.9e-84 cotF M Spore coat protein
DFGHHELI_02779 1.5e-67 ydeP3 K Transcriptional regulator
DFGHHELI_02780 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
DFGHHELI_02781 7.5e-58
DFGHHELI_02783 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
DFGHHELI_02784 4.8e-110 K TipAS antibiotic-recognition domain
DFGHHELI_02785 5.3e-123
DFGHHELI_02786 2.3e-66 yybH S SnoaL-like domain
DFGHHELI_02787 1e-103 yybG S Pentapeptide repeat-containing protein
DFGHHELI_02788 7.3e-209 ynfM EGP Major facilitator Superfamily
DFGHHELI_02789 2.9e-165 yybE K Transcriptional regulator
DFGHHELI_02790 6.1e-76 yjcF S Acetyltransferase (GNAT) domain
DFGHHELI_02791 3e-76 yybC
DFGHHELI_02792 3.3e-126 S Metallo-beta-lactamase superfamily
DFGHHELI_02793 5.6e-77 yybA 2.3.1.57 K transcriptional
DFGHHELI_02794 6.5e-70 yjcF S Acetyltransferase (GNAT) domain
DFGHHELI_02795 2.5e-96 yyaS S Membrane
DFGHHELI_02796 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
DFGHHELI_02797 1.3e-65 yyaQ S YjbR
DFGHHELI_02798 1e-104 yyaP 1.5.1.3 H RibD C-terminal domain
DFGHHELI_02799 1.6e-244 tetL EGP Major facilitator Superfamily
DFGHHELI_02800 2.5e-60 yyaN K MerR HTH family regulatory protein
DFGHHELI_02801 6.3e-160 yyaM EG EamA-like transporter family
DFGHHELI_02802 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
DFGHHELI_02803 4.4e-166 yyaK S CAAX protease self-immunity
DFGHHELI_02804 1.5e-242 EGP Major facilitator superfamily
DFGHHELI_02805 1.8e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
DFGHHELI_02806 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_02807 4.4e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
DFGHHELI_02808 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
DFGHHELI_02809 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DFGHHELI_02810 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DFGHHELI_02811 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
DFGHHELI_02812 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DFGHHELI_02813 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DFGHHELI_02814 2.3e-33 yyzM S protein conserved in bacteria
DFGHHELI_02815 8.1e-177 yyaD S Membrane
DFGHHELI_02816 1.6e-111 yyaC S Sporulation protein YyaC
DFGHHELI_02817 2.1e-149 spo0J K Belongs to the ParB family
DFGHHELI_02818 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
DFGHHELI_02819 9.6e-74 S Bacterial PH domain
DFGHHELI_02820 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
DFGHHELI_02821 7e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
DFGHHELI_02822 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DFGHHELI_02823 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DFGHHELI_02824 6.5e-108 jag S single-stranded nucleic acid binding R3H
DFGHHELI_02825 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DFGHHELI_02826 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DFGHHELI_02827 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DFGHHELI_02828 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DFGHHELI_02829 2.4e-33 yaaA S S4 domain
DFGHHELI_02830 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DFGHHELI_02831 1.8e-37 yaaB S Domain of unknown function (DUF370)
DFGHHELI_02832 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFGHHELI_02833 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFGHHELI_02836 2.3e-156 ydhU P Catalase
DFGHHELI_02837 4.5e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
DFGHHELI_02838 7.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
DFGHHELI_02839 9.5e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
DFGHHELI_02840 3.7e-131 ydhQ K UTRA
DFGHHELI_02841 3.4e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DFGHHELI_02842 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DFGHHELI_02843 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
DFGHHELI_02844 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
DFGHHELI_02845 2.3e-199 pbuE EGP Major facilitator Superfamily
DFGHHELI_02846 2.5e-98 ydhK M Protein of unknown function (DUF1541)
DFGHHELI_02847 9e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DFGHHELI_02848 8.6e-84 K Acetyltransferase (GNAT) domain
DFGHHELI_02850 7.4e-67 frataxin S Domain of unknown function (DU1801)
DFGHHELI_02851 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
DFGHHELI_02852 6.7e-125
DFGHHELI_02853 5.9e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DFGHHELI_02854 1.2e-241 ydhD M Glycosyl hydrolase
DFGHHELI_02855 8.5e-122 ydhC K FCD
DFGHHELI_02856 1.2e-121 ydhB S membrane transporter protein
DFGHHELI_02857 2.2e-208 tcaB EGP Major facilitator Superfamily
DFGHHELI_02858 2.4e-69 ydgJ K Winged helix DNA-binding domain
DFGHHELI_02859 1e-113 drgA C nitroreductase
DFGHHELI_02860 0.0 ydgH S drug exporters of the RND superfamily
DFGHHELI_02861 4.2e-80 K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_02862 8.7e-90 dinB S DinB family
DFGHHELI_02863 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_02864 9.8e-305 expZ S ABC transporter
DFGHHELI_02865 1.3e-84 yycN 2.3.1.128 K Acetyltransferase
DFGHHELI_02866 1.4e-51 S DoxX-like family
DFGHHELI_02867 2.6e-98 K Bacterial regulatory proteins, tetR family
DFGHHELI_02868 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
DFGHHELI_02869 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
DFGHHELI_02870 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
DFGHHELI_02871 1.1e-119 ydfS S Protein of unknown function (DUF421)
DFGHHELI_02872 2.7e-98 ydfR S Protein of unknown function (DUF421)
DFGHHELI_02874 4.4e-30
DFGHHELI_02875 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
DFGHHELI_02876 1.7e-54 traF CO Thioredoxin
DFGHHELI_02877 1.2e-62 mhqP S DoxX
DFGHHELI_02878 1.2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
DFGHHELI_02879 1.4e-107 ydfN C nitroreductase
DFGHHELI_02880 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DFGHHELI_02881 2.7e-146 K Bacterial transcription activator, effector binding domain
DFGHHELI_02882 4.2e-116 S Protein of unknown function (DUF554)
DFGHHELI_02883 0.0 ydfJ S drug exporters of the RND superfamily
DFGHHELI_02884 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_02885 1.4e-177 ydfH 2.7.13.3 T Histidine kinase
DFGHHELI_02887 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DFGHHELI_02888 7.3e-121 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
DFGHHELI_02889 5e-116 ydfE S Flavin reductase like domain
DFGHHELI_02890 8.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_02891 2.2e-149 ydfC EG EamA-like transporter family
DFGHHELI_02892 6.1e-123 T Transcriptional regulatory protein, C terminal
DFGHHELI_02893 7.5e-224 T GHKL domain
DFGHHELI_02894 1.5e-158
DFGHHELI_02895 7e-123 nodB1 G deacetylase
DFGHHELI_02896 4.1e-148 lytR K Transcriptional regulator
DFGHHELI_02897 8.3e-145 ydfB J GNAT acetyltransferase
DFGHHELI_02898 7e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DFGHHELI_02899 2.8e-57 arsR K transcriptional
DFGHHELI_02900 3.2e-104 ydeS K Transcriptional regulator
DFGHHELI_02901 1.9e-193 ydeR EGP Major facilitator Superfamily
DFGHHELI_02902 6.1e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
DFGHHELI_02903 4.8e-69 ydeP K Transcriptional regulator
DFGHHELI_02904 1.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
DFGHHELI_02905 3e-56 K HxlR-like helix-turn-helix
DFGHHELI_02906 1e-90 ydeN S Serine hydrolase
DFGHHELI_02907 1.3e-72 maoC I N-terminal half of MaoC dehydratase
DFGHHELI_02908 3.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_02909 1.8e-153 ydeK EG -transporter
DFGHHELI_02910 3.4e-84 K Transcriptional regulator C-terminal region
DFGHHELI_02911 1.6e-13 ptsH G Phosphocarrier protein HPr
DFGHHELI_02912 1.1e-31 S SNARE associated Golgi protein
DFGHHELI_02913 2.4e-108
DFGHHELI_02914 1.3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
DFGHHELI_02915 1e-44 ydeH
DFGHHELI_02916 7.1e-218 ydeG EGP Major facilitator superfamily
DFGHHELI_02917 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_02918 1.1e-164 ydeE K AraC family transcriptional regulator
DFGHHELI_02919 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DFGHHELI_02920 5.3e-164 rhaS5 K AraC-like ligand binding domain
DFGHHELI_02921 1.2e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DFGHHELI_02922 2.3e-78 carD K Transcription factor
DFGHHELI_02923 8.7e-30 cspL K Cold shock
DFGHHELI_02924 8.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
DFGHHELI_02925 9.6e-40
DFGHHELI_02926 3.4e-33 K Helix-turn-helix XRE-family like proteins
DFGHHELI_02927 1.5e-146 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DFGHHELI_02928 1e-42
DFGHHELI_02929 8.9e-46 S SMI1-KNR4 cell-wall
DFGHHELI_02930 2.1e-40
DFGHHELI_02932 9.1e-31
DFGHHELI_02933 9.7e-32 nicK L Replication initiation factor
DFGHHELI_02934 1.9e-122 nicK L Replication initiation factor
DFGHHELI_02935 1e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_02936 3.5e-167 ydjN U Involved in the tonB-independent uptake of proteins
DFGHHELI_02937 9.3e-30 ydjM M Lytic transglycolase
DFGHHELI_02938 1.9e-91
DFGHHELI_02940 2.1e-21 S response regulator aspartate phosphatase
DFGHHELI_02941 7.7e-08 S response regulator aspartate phosphatase
DFGHHELI_02942 8.5e-67
DFGHHELI_02951 8.9e-83 ydcK S Belongs to the SprT family
DFGHHELI_02952 0.0 yhgF K COG2183 Transcriptional accessory protein
DFGHHELI_02953 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
DFGHHELI_02954 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DFGHHELI_02955 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
DFGHHELI_02956 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
DFGHHELI_02957 7.1e-189 rsbU 3.1.3.3 KT phosphatase
DFGHHELI_02958 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
DFGHHELI_02959 5.2e-57 rsbS T antagonist
DFGHHELI_02960 1.3e-143 rsbR T Positive regulator of sigma-B
DFGHHELI_02961 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
DFGHHELI_02962 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
DFGHHELI_02963 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DFGHHELI_02964 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
DFGHHELI_02965 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DFGHHELI_02966 1.5e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
DFGHHELI_02967 6.6e-260 ydbT S Membrane
DFGHHELI_02968 2.1e-82 ydbS S Bacterial PH domain
DFGHHELI_02969 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DFGHHELI_02970 8.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DFGHHELI_02971 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DFGHHELI_02972 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DFGHHELI_02973 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DFGHHELI_02974 2.2e-07 S Fur-regulated basic protein A
DFGHHELI_02975 1.1e-18 S Fur-regulated basic protein B
DFGHHELI_02976 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
DFGHHELI_02977 2.7e-52 ydbL
DFGHHELI_02978 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DFGHHELI_02979 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
DFGHHELI_02980 4.4e-181 ydbI S AI-2E family transporter
DFGHHELI_02981 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFGHHELI_02982 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
DFGHHELI_02983 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DFGHHELI_02984 9.6e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
DFGHHELI_02985 2.3e-153 ydbD P Catalase
DFGHHELI_02986 2e-61 ydbC S Domain of unknown function (DUF4937
DFGHHELI_02987 2.6e-58 ydbB G Cupin domain
DFGHHELI_02989 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
DFGHHELI_02990 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
DFGHHELI_02992 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
DFGHHELI_02993 9.4e-40
DFGHHELI_02995 1.4e-72 sdpB S Protein conserved in bacteria
DFGHHELI_02996 1.8e-27
DFGHHELI_02998 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DFGHHELI_02999 4.4e-43 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
DFGHHELI_03000 0.0 ydaO E amino acid
DFGHHELI_03001 0.0 ydaN S Bacterial cellulose synthase subunit
DFGHHELI_03002 4.5e-233 ydaM M Glycosyl transferase family group 2
DFGHHELI_03003 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
DFGHHELI_03004 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
DFGHHELI_03005 1.8e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
DFGHHELI_03006 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DFGHHELI_03007 2.5e-74 lrpC K Transcriptional regulator
DFGHHELI_03008 1.4e-44 ydzA EGP Major facilitator Superfamily
DFGHHELI_03009 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
DFGHHELI_03010 6.8e-77 ydaG 1.4.3.5 S general stress protein
DFGHHELI_03011 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DFGHHELI_03012 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
DFGHHELI_03013 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_03014 3.4e-98 ydaC Q Methyltransferase domain
DFGHHELI_03015 6e-293 ydaB IQ acyl-CoA ligase
DFGHHELI_03016 0.0 mtlR K transcriptional regulator, MtlR
DFGHHELI_03017 3.4e-174 ydhF S Oxidoreductase
DFGHHELI_03018 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
DFGHHELI_03019 1.4e-49 yczJ S biosynthesis
DFGHHELI_03021 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
DFGHHELI_03022 2.7e-132 kipR K Transcriptional regulator
DFGHHELI_03023 1.1e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
DFGHHELI_03024 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
DFGHHELI_03025 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
DFGHHELI_03026 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
DFGHHELI_03027 8.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
DFGHHELI_03028 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DFGHHELI_03030 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
DFGHHELI_03031 1.3e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
DFGHHELI_03032 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DFGHHELI_03033 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
DFGHHELI_03034 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
DFGHHELI_03035 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
DFGHHELI_03036 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
DFGHHELI_03037 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
DFGHHELI_03038 2.6e-53
DFGHHELI_03039 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
DFGHHELI_03040 1.2e-307 ycnJ P protein, homolog of Cu resistance protein CopC
DFGHHELI_03041 9.3e-99 ycnI S protein conserved in bacteria
DFGHHELI_03042 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_03043 6.1e-149 glcU U Glucose uptake
DFGHHELI_03044 6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DFGHHELI_03045 7.4e-239 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DFGHHELI_03046 1.4e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DFGHHELI_03047 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
DFGHHELI_03048 1.6e-45 ycnE S Monooxygenase
DFGHHELI_03049 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
DFGHHELI_03050 5.5e-153 ycnC K Transcriptional regulator
DFGHHELI_03051 3.2e-251 ycnB EGP Major facilitator Superfamily
DFGHHELI_03052 1.9e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
DFGHHELI_03053 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
DFGHHELI_03054 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03055 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03056 2.4e-240 lysC 2.7.2.4 E Belongs to the aspartokinase family
DFGHHELI_03059 2e-70 S aspartate phosphatase
DFGHHELI_03060 2.4e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DFGHHELI_03061 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_03062 6.2e-202 yclI V ABC transporter (permease) YclI
DFGHHELI_03063 7.3e-121 yclH P ABC transporter
DFGHHELI_03064 3e-196 gerKB F Spore germination protein
DFGHHELI_03065 1.6e-230 gerKC S spore germination
DFGHHELI_03066 7.5e-281 gerKA EG Spore germination protein
DFGHHELI_03068 9.1e-309 yclG M Pectate lyase superfamily protein
DFGHHELI_03069 8.1e-266 dtpT E amino acid peptide transporter
DFGHHELI_03070 1.9e-155 yclE 3.4.11.5 S Alpha beta hydrolase
DFGHHELI_03071 6.6e-81 yclD
DFGHHELI_03072 4e-39 bsdD 4.1.1.61 S response to toxic substance
DFGHHELI_03073 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
DFGHHELI_03074 3.2e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DFGHHELI_03075 1.9e-161 bsdA K LysR substrate binding domain
DFGHHELI_03076 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DFGHHELI_03077 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
DFGHHELI_03078 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
DFGHHELI_03079 9.7e-115 yczE S membrane
DFGHHELI_03080 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
DFGHHELI_03081 1.1e-250 ycxD K GntR family transcriptional regulator
DFGHHELI_03082 6.9e-162 ycxC EG EamA-like transporter family
DFGHHELI_03083 1.3e-88 S YcxB-like protein
DFGHHELI_03084 1e-221 EGP Major Facilitator Superfamily
DFGHHELI_03085 2.2e-139 srfAD Q thioesterase
DFGHHELI_03086 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
DFGHHELI_03087 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_03088 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_03089 1.3e-63 hxlR K transcriptional
DFGHHELI_03090 1.2e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
DFGHHELI_03091 1e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
DFGHHELI_03092 8.7e-171 tlpC 2.7.13.3 NT chemotaxis protein
DFGHHELI_03093 1e-70 nucA M Deoxyribonuclease NucA/NucB
DFGHHELI_03094 3.2e-68 nin S Competence protein J (ComJ)
DFGHHELI_03095 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DFGHHELI_03096 1e-120 S AAA domain
DFGHHELI_03097 9.3e-24
DFGHHELI_03098 5.7e-39 K MarR family
DFGHHELI_03099 7.8e-52 yckD S Protein of unknown function (DUF2680)
DFGHHELI_03100 2e-42 yckC S membrane
DFGHHELI_03101 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
DFGHHELI_03102 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
DFGHHELI_03103 3.9e-226 yciC S GTPases (G3E family)
DFGHHELI_03104 7.2e-55 yciB M ErfK YbiS YcfS YnhG
DFGHHELI_03105 3.1e-30 yciB M ErfK YbiS YcfS YnhG
DFGHHELI_03106 3.7e-168 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
DFGHHELI_03107 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
DFGHHELI_03108 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
DFGHHELI_03109 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DFGHHELI_03110 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DFGHHELI_03111 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
DFGHHELI_03112 4.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
DFGHHELI_03113 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DFGHHELI_03114 6.5e-159 I alpha/beta hydrolase fold
DFGHHELI_03115 1.2e-139 ycgR S permeases
DFGHHELI_03116 1.3e-146 ycgQ S membrane
DFGHHELI_03117 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
DFGHHELI_03118 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFGHHELI_03119 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
DFGHHELI_03120 5.1e-170 ycgM E Proline dehydrogenase
DFGHHELI_03121 2.4e-144 ycgL S Predicted nucleotidyltransferase
DFGHHELI_03122 1e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
DFGHHELI_03123 6e-177 oxyR3 K LysR substrate binding domain
DFGHHELI_03124 3.4e-143 yafE Q ubiE/COQ5 methyltransferase family
DFGHHELI_03125 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DFGHHELI_03126 1.6e-108 tmrB S AAA domain
DFGHHELI_03127 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DFGHHELI_03128 2.4e-112 ycgI S Domain of unknown function (DUF1989)
DFGHHELI_03129 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_03130 1.5e-151 yqcI S YqcI/YcgG family
DFGHHELI_03131 6.8e-113 ycgF E Lysine exporter protein LysE YggA
DFGHHELI_03132 7.5e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_03133 2.5e-262 mdr EGP Major facilitator Superfamily
DFGHHELI_03134 6.3e-288 lctP C L-lactate permease
DFGHHELI_03135 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DFGHHELI_03136 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
DFGHHELI_03137 4.1e-81 ycgB
DFGHHELI_03138 8.7e-257 ycgA S Membrane
DFGHHELI_03139 1.4e-217 amhX S amidohydrolase
DFGHHELI_03140 5.3e-164 opuAC E glycine betaine
DFGHHELI_03141 8.5e-127 opuAB P glycine betaine
DFGHHELI_03142 1.9e-228 proV 3.6.3.32 E glycine betaine
DFGHHELI_03143 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
DFGHHELI_03144 1.5e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
DFGHHELI_03145 1.1e-217 naiP P Uncharacterised MFS-type transporter YbfB
DFGHHELI_03146 2e-192 yceH P Belongs to the TelA family
DFGHHELI_03147 0.0 yceG S Putative component of 'biosynthetic module'
DFGHHELI_03148 6.3e-137 terC P Protein of unknown function (DUF475)
DFGHHELI_03149 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
DFGHHELI_03150 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
DFGHHELI_03151 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
DFGHHELI_03152 2.6e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_03153 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DFGHHELI_03154 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DFGHHELI_03155 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
DFGHHELI_03156 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
DFGHHELI_03157 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
DFGHHELI_03158 1e-172 S response regulator aspartate phosphatase
DFGHHELI_03159 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
DFGHHELI_03160 4.6e-261 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_03161 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_03162 6.6e-177 ycdA S Domain of unknown function (DUF5105)
DFGHHELI_03163 7.8e-174 yccK C Aldo keto reductase
DFGHHELI_03164 2.7e-200 natB CP ABC-2 family transporter protein
DFGHHELI_03165 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
DFGHHELI_03166 1.2e-126 lytR_2 T LytTr DNA-binding domain
DFGHHELI_03167 2e-156 2.7.13.3 T GHKL domain
DFGHHELI_03168 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
DFGHHELI_03169 4.5e-59 S RDD family
DFGHHELI_03170 2.4e-113 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
DFGHHELI_03171 8.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DFGHHELI_03172 4.1e-101 yxaF K Transcriptional regulator
DFGHHELI_03173 6.7e-225 lmrB EGP the major facilitator superfamily
DFGHHELI_03174 1.9e-203 ycbU E Selenocysteine lyase
DFGHHELI_03175 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DFGHHELI_03176 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DFGHHELI_03177 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DFGHHELI_03178 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
DFGHHELI_03179 1.9e-11 ycbR T vWA found in TerF C terminus
DFGHHELI_03180 2.2e-78 sleB 3.5.1.28 M Cell wall
DFGHHELI_03181 4.1e-52 ycbP S Protein of unknown function (DUF2512)
DFGHHELI_03182 2.1e-112 S ABC-2 family transporter protein
DFGHHELI_03183 5.9e-166 ycbN V ABC transporter, ATP-binding protein
DFGHHELI_03184 1.6e-166 T PhoQ Sensor
DFGHHELI_03185 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_03186 1.2e-71 eamA1 EG spore germination
DFGHHELI_03187 6.6e-47 eamA1 EG spore germination
DFGHHELI_03188 1.3e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
DFGHHELI_03189 5.9e-174 ycbJ S Macrolide 2'-phosphotransferase
DFGHHELI_03190 1.2e-291 garD 4.2.1.42, 4.2.1.7 G Altronate
DFGHHELI_03191 3.1e-122 ycbG K FCD
DFGHHELI_03192 8.5e-262 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DFGHHELI_03193 1.5e-250 gudP G COG0477 Permeases of the major facilitator superfamily
DFGHHELI_03194 5.8e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DFGHHELI_03195 8.9e-170 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
DFGHHELI_03196 5.9e-161 glnL T Regulator
DFGHHELI_03197 8.1e-222 phoQ 2.7.13.3 T Histidine kinase
DFGHHELI_03198 2.4e-181 glsA 3.5.1.2 E Belongs to the glutaminase family
DFGHHELI_03199 1.6e-255 agcS E Sodium alanine symporter
DFGHHELI_03201 1.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
DFGHHELI_03202 5.7e-261 mmuP E amino acid
DFGHHELI_03203 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DFGHHELI_03205 4.9e-128 K UTRA
DFGHHELI_03206 1.3e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DFGHHELI_03207 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_03208 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFGHHELI_03209 3.9e-192 yceA S Belongs to the UPF0176 family
DFGHHELI_03210 9.3e-253 S Erythromycin esterase
DFGHHELI_03211 9.5e-43 ybfN
DFGHHELI_03212 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
DFGHHELI_03213 2.7e-85 ybfM S SNARE associated Golgi protein
DFGHHELI_03214 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFGHHELI_03215 3e-167 S Alpha/beta hydrolase family
DFGHHELI_03217 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
DFGHHELI_03218 1.3e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DFGHHELI_03219 5.2e-145 msmR K AraC-like ligand binding domain
DFGHHELI_03220 1.8e-159 ybfH EG EamA-like transporter family
DFGHHELI_03222 1.4e-218 ybfB G COG0477 Permeases of the major facilitator superfamily
DFGHHELI_03223 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
DFGHHELI_03224 1.5e-34 S Protein of unknown function (DUF2651)
DFGHHELI_03225 9.5e-258 glpT G -transporter
DFGHHELI_03226 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DFGHHELI_03227 1.8e-290 ybeC E amino acid
DFGHHELI_03228 4.9e-41 ybyB
DFGHHELI_03229 5.1e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
DFGHHELI_03230 3.7e-148 ybxI 3.5.2.6 V beta-lactamase
DFGHHELI_03231 4.9e-30 ybxH S Family of unknown function (DUF5370)
DFGHHELI_03232 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
DFGHHELI_03233 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_03234 4.4e-214 ybdO S Domain of unknown function (DUF4885)
DFGHHELI_03235 1.3e-151 ybdN
DFGHHELI_03236 3.7e-137 KLT Protein tyrosine kinase
DFGHHELI_03238 1.2e-167 T His Kinase A (phospho-acceptor) domain
DFGHHELI_03239 2.9e-122 T Transcriptional regulatory protein, C terminal
DFGHHELI_03240 6.2e-151 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DFGHHELI_03241 3.7e-78 txn CO Thioredoxin-like
DFGHHELI_03242 7.8e-91 C HEAT repeats
DFGHHELI_03243 8.4e-246 skfF S ABC transporter
DFGHHELI_03244 8e-134 skfE V ABC transporter
DFGHHELI_03245 4.6e-277 V CAAX protease self-immunity
DFGHHELI_03246 9.1e-239 J 4Fe-4S single cluster domain
DFGHHELI_03248 4.5e-203 ybcL EGP Major facilitator Superfamily
DFGHHELI_03249 5.1e-50 ybzH K Helix-turn-helix domain
DFGHHELI_03250 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
DFGHHELI_03251 1.9e-46
DFGHHELI_03253 6.5e-93 can 4.2.1.1 P carbonic anhydrase
DFGHHELI_03254 0.0 ybcC S Belongs to the UPF0753 family
DFGHHELI_03255 1.3e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DFGHHELI_03256 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DFGHHELI_03257 3.4e-120 adaA 3.2.2.21 K Transcriptional regulator
DFGHHELI_03258 5.3e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DFGHHELI_03260 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DFGHHELI_03261 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DFGHHELI_03262 1.3e-220 ybbR S protein conserved in bacteria
DFGHHELI_03263 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DFGHHELI_03264 6.5e-100 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
DFGHHELI_03265 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
DFGHHELI_03271 8.4e-73 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
DFGHHELI_03272 8.9e-81 ybbJ J acetyltransferase
DFGHHELI_03273 3.3e-153 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DFGHHELI_03274 5e-143 ybbH K transcriptional
DFGHHELI_03275 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_03276 3.8e-226 yfeW 3.4.16.4 V Belongs to the UPF0214 family
DFGHHELI_03277 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
DFGHHELI_03278 1.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
DFGHHELI_03279 4.7e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
DFGHHELI_03280 4e-165 feuA P Iron-uptake system-binding protein
DFGHHELI_03281 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03282 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03283 1.4e-141 ybbA S Putative esterase
DFGHHELI_03284 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
DFGHHELI_03285 1.8e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
DFGHHELI_03287 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
DFGHHELI_03288 1.1e-147 malD P transport
DFGHHELI_03289 7.7e-155 malA S Protein of unknown function (DUF1189)
DFGHHELI_03290 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
DFGHHELI_03291 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
DFGHHELI_03292 3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
DFGHHELI_03293 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DFGHHELI_03295 2.3e-173 S Patatin-like phospholipase
DFGHHELI_03296 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
DFGHHELI_03297 7.1e-50 sugE P Small Multidrug Resistance protein
DFGHHELI_03298 1.5e-50 ykkC P Small Multidrug Resistance protein
DFGHHELI_03299 9.7e-106 yvdT K Transcriptional regulator
DFGHHELI_03300 1.8e-295 yveA E amino acid
DFGHHELI_03301 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
DFGHHELI_03302 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
DFGHHELI_03303 6.7e-259 pbpE V Beta-lactamase
DFGHHELI_03304 1.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DFGHHELI_03305 1.2e-74 MA20_18690 S Protein of unknown function (DUF3237)
DFGHHELI_03306 1.7e-92 padC Q Phenolic acid decarboxylase
DFGHHELI_03307 7.5e-280 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
DFGHHELI_03308 4.1e-75 slr K transcriptional
DFGHHELI_03309 4e-122 ywqC M biosynthesis protein
DFGHHELI_03310 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
DFGHHELI_03311 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
DFGHHELI_03312 8e-221 epsD GT4 M Glycosyl transferase 4-like
DFGHHELI_03313 2.7e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DFGHHELI_03314 4.9e-218 epsF GT4 M Glycosyl transferases group 1
DFGHHELI_03315 1.1e-206 epsG S EpsG family
DFGHHELI_03316 4.1e-192 epsH GT2 S Glycosyltransferase like family 2
DFGHHELI_03317 5.8e-205 epsI GM pyruvyl transferase
DFGHHELI_03318 1e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
DFGHHELI_03319 8.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_03320 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DFGHHELI_03321 5.1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
DFGHHELI_03322 3.4e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
DFGHHELI_03323 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
DFGHHELI_03324 1e-31 yvfG S YvfG protein
DFGHHELI_03325 9.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
DFGHHELI_03326 6.3e-307 yvfH C L-lactate permease
DFGHHELI_03327 1e-112 yvfI K COG2186 Transcriptional regulators
DFGHHELI_03328 1.8e-184 lacR K Transcriptional regulator
DFGHHELI_03329 8.8e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
DFGHHELI_03330 1.2e-230 malC P COG1175 ABC-type sugar transport systems, permease components
DFGHHELI_03331 7.2e-150 ganQ P transport
DFGHHELI_03332 0.0 lacA 3.2.1.23 G beta-galactosidase
DFGHHELI_03333 2.4e-250 galA 3.2.1.89 G arabinogalactan
DFGHHELI_03334 1e-194 rsbU 3.1.3.3 T response regulator
DFGHHELI_03335 5.7e-157 rsbQ S Alpha/beta hydrolase family
DFGHHELI_03336 2.6e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
DFGHHELI_03337 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
DFGHHELI_03338 3e-196 desK 2.7.13.3 T Histidine kinase
DFGHHELI_03339 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_03340 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DFGHHELI_03341 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
DFGHHELI_03342 1.3e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DFGHHELI_03343 5.4e-192 yvbX S Glycosyl hydrolase
DFGHHELI_03344 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_03345 9.4e-156 yvbV EG EamA-like transporter family
DFGHHELI_03346 3.9e-159 yvbU K Transcriptional regulator
DFGHHELI_03347 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DFGHHELI_03348 5.5e-203 araR K transcriptional
DFGHHELI_03349 1.6e-252 araE EGP Major facilitator Superfamily
DFGHHELI_03350 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DFGHHELI_03351 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DFGHHELI_03352 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DFGHHELI_03353 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DFGHHELI_03354 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
DFGHHELI_03355 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DFGHHELI_03356 1.2e-74 yvbK 3.1.3.25 K acetyltransferase
DFGHHELI_03357 0.0 tcaA S response to antibiotic
DFGHHELI_03358 6.1e-123 exoY M Membrane
DFGHHELI_03359 8.6e-113 yvbH S YvbH-like oligomerisation region
DFGHHELI_03360 3.2e-102 yvbG U UPF0056 membrane protein
DFGHHELI_03361 3.5e-97 yvbF K Belongs to the GbsR family
DFGHHELI_03362 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DFGHHELI_03363 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
DFGHHELI_03364 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DFGHHELI_03365 5e-106 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
DFGHHELI_03366 3.3e-60 yvbF K Belongs to the GbsR family
DFGHHELI_03367 1.6e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DFGHHELI_03368 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
DFGHHELI_03369 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DFGHHELI_03370 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
DFGHHELI_03371 8e-217 NT chemotaxis protein
DFGHHELI_03372 2.2e-54 yodB K transcriptional
DFGHHELI_03373 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
DFGHHELI_03374 4e-69 K transcriptional
DFGHHELI_03375 7.5e-36 yvzC K Transcriptional
DFGHHELI_03376 3.4e-151 yvaM S Serine aminopeptidase, S33
DFGHHELI_03377 2.4e-23 secG U Preprotein translocase subunit SecG
DFGHHELI_03378 5.6e-143 est 3.1.1.1 S Carboxylesterase
DFGHHELI_03379 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DFGHHELI_03380 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DFGHHELI_03382 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_03383 5.2e-96 K Bacterial regulatory proteins, tetR family
DFGHHELI_03384 1.8e-54 yvaE P Small Multidrug Resistance protein
DFGHHELI_03385 1.1e-71 yvaD S Family of unknown function (DUF5360)
DFGHHELI_03386 0.0 yvaC S Fusaric acid resistance protein-like
DFGHHELI_03387 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DFGHHELI_03388 3.4e-194 yvaA 1.1.1.371 S Oxidoreductase
DFGHHELI_03389 2.2e-48 csoR S transcriptional
DFGHHELI_03390 1.5e-29 copZ P Copper resistance protein CopZ
DFGHHELI_03391 0.0 copA 3.6.3.54 P P-type ATPase
DFGHHELI_03392 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DFGHHELI_03393 1.6e-104 bdbD O Thioredoxin
DFGHHELI_03394 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
DFGHHELI_03395 4.1e-107 yvgT S membrane
DFGHHELI_03396 0.0 helD 3.6.4.12 L DNA helicase
DFGHHELI_03397 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DFGHHELI_03398 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
DFGHHELI_03399 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
DFGHHELI_03400 2.1e-85 yvgO
DFGHHELI_03401 2.5e-155 yvgN S reductase
DFGHHELI_03402 5.2e-119 modB P COG4149 ABC-type molybdate transport system, permease component
DFGHHELI_03403 1.1e-133 modA P COG0725 ABC-type molybdate transport system, periplasmic component
DFGHHELI_03404 1.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
DFGHHELI_03405 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DFGHHELI_03406 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
DFGHHELI_03407 6.5e-16 S Small spore protein J (Spore_SspJ)
DFGHHELI_03408 4.9e-236 yvsH E Arginine ornithine antiporter
DFGHHELI_03409 2e-177 fhuD P ABC transporter
DFGHHELI_03410 1.8e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03411 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03412 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
DFGHHELI_03413 4.8e-176 M Efflux transporter rnd family, mfp subunit
DFGHHELI_03414 7.9e-123 macB V ABC transporter, ATP-binding protein
DFGHHELI_03415 5.2e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
DFGHHELI_03416 1.3e-64 yvrL S Regulatory protein YrvL
DFGHHELI_03417 4e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
DFGHHELI_03418 2.4e-19 S YvrJ protein family
DFGHHELI_03419 9.5e-98 yvrI K RNA polymerase
DFGHHELI_03420 7.2e-23
DFGHHELI_03421 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_03422 0.0 T PhoQ Sensor
DFGHHELI_03423 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
DFGHHELI_03424 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_03425 6.5e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
DFGHHELI_03426 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03427 4.1e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
DFGHHELI_03428 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
DFGHHELI_03429 4.8e-227 yvqJ EGP Major facilitator Superfamily
DFGHHELI_03430 6.2e-61 liaI S membrane
DFGHHELI_03431 6.2e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
DFGHHELI_03432 2.3e-127 liaG S Putative adhesin
DFGHHELI_03433 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
DFGHHELI_03434 1.3e-185 vraS 2.7.13.3 T Histidine kinase
DFGHHELI_03435 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_03436 7.6e-184 gerAC S Spore germination B3/ GerAC like, C-terminal
DFGHHELI_03437 3.8e-196 gerAB E Spore germination protein
DFGHHELI_03438 5.3e-246 gerAA EG Spore germination protein
DFGHHELI_03439 2.3e-24 S Protein of unknown function (DUF3970)
DFGHHELI_03440 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DFGHHELI_03441 4.3e-158 yuxN K Transcriptional regulator
DFGHHELI_03442 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
DFGHHELI_03443 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DFGHHELI_03444 1.5e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DFGHHELI_03445 1.2e-79 dps P Ferritin-like domain
DFGHHELI_03446 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_03447 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
DFGHHELI_03448 1.9e-66 S YusW-like protein
DFGHHELI_03449 3.9e-153 yusV 3.6.3.34 HP ABC transporter
DFGHHELI_03450 3.3e-46 yusU S Protein of unknown function (DUF2573)
DFGHHELI_03451 9.7e-158 yusT K LysR substrate binding domain
DFGHHELI_03452 1e-104 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_03453 6e-64 yusQ S Tautomerase enzyme
DFGHHELI_03454 3.2e-292 yusP P Major facilitator superfamily
DFGHHELI_03455 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
DFGHHELI_03456 5.4e-53 yusN M Coat F domain
DFGHHELI_03457 2.5e-39
DFGHHELI_03458 4.2e-164 fadM E Proline dehydrogenase
DFGHHELI_03459 8.1e-09 S YuzL-like protein
DFGHHELI_03460 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
DFGHHELI_03461 5.5e-217 fadA 2.3.1.16 I Belongs to the thiolase family
DFGHHELI_03462 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
DFGHHELI_03463 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
DFGHHELI_03464 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
DFGHHELI_03465 4.1e-39 yusG S Protein of unknown function (DUF2553)
DFGHHELI_03466 4.8e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
DFGHHELI_03467 1.2e-54 traF CO Thioredoxin
DFGHHELI_03468 3.2e-56 yusD S SCP-2 sterol transfer family
DFGHHELI_03469 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DFGHHELI_03470 7.5e-94 metI P COG2011 ABC-type metal ion transport system, permease component
DFGHHELI_03471 1.2e-146 metQ P Belongs to the NlpA lipoprotein family
DFGHHELI_03472 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DFGHHELI_03473 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DFGHHELI_03474 1.4e-245 sufD O assembly protein SufD
DFGHHELI_03475 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DFGHHELI_03476 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
DFGHHELI_03477 3.5e-271 sufB O FeS cluster assembly
DFGHHELI_03478 6.6e-156
DFGHHELI_03479 2.3e-41
DFGHHELI_03481 3.8e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
DFGHHELI_03482 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
DFGHHELI_03483 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
DFGHHELI_03484 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
DFGHHELI_03485 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
DFGHHELI_03486 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
DFGHHELI_03487 4.8e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
DFGHHELI_03488 1.6e-134 yurK K UTRA
DFGHHELI_03489 5.9e-205 msmX P Belongs to the ABC transporter superfamily
DFGHHELI_03490 3.5e-168 bsn L Ribonuclease
DFGHHELI_03491 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
DFGHHELI_03492 4.6e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
DFGHHELI_03493 6.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DFGHHELI_03494 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
DFGHHELI_03495 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
DFGHHELI_03496 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
DFGHHELI_03497 2e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
DFGHHELI_03500 1.9e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
DFGHHELI_03501 1.2e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
DFGHHELI_03502 5.6e-223 pbuX F xanthine
DFGHHELI_03503 5e-230 pbuX F Permease family
DFGHHELI_03504 7e-300 pucR QT COG2508 Regulator of polyketide synthase expression
DFGHHELI_03505 3.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
DFGHHELI_03506 2.8e-60 yunG
DFGHHELI_03507 4.8e-170 yunF S Protein of unknown function DUF72
DFGHHELI_03508 2.2e-140 yunE S membrane transporter protein
DFGHHELI_03509 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DFGHHELI_03510 3.1e-47 yunC S Domain of unknown function (DUF1805)
DFGHHELI_03511 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
DFGHHELI_03512 1.3e-195 lytH M Peptidase, M23
DFGHHELI_03513 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DFGHHELI_03514 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DFGHHELI_03515 9.7e-48 yutD S protein conserved in bacteria
DFGHHELI_03516 8.6e-75 yutE S Protein of unknown function DUF86
DFGHHELI_03517 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DFGHHELI_03518 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
DFGHHELI_03519 5e-198 yutH S Spore coat protein
DFGHHELI_03520 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
DFGHHELI_03521 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DFGHHELI_03522 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DFGHHELI_03523 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
DFGHHELI_03524 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
DFGHHELI_03525 3.3e-55 yuzD S protein conserved in bacteria
DFGHHELI_03526 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
DFGHHELI_03527 3.2e-39 yuzB S Belongs to the UPF0349 family
DFGHHELI_03528 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DFGHHELI_03529 1.1e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DFGHHELI_03530 3.7e-63 erpA S Belongs to the HesB IscA family
DFGHHELI_03531 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DFGHHELI_03532 3.6e-114 paiB K Putative FMN-binding domain
DFGHHELI_03533 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DFGHHELI_03535 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
DFGHHELI_03536 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
DFGHHELI_03537 8.4e-27 yuiB S Putative membrane protein
DFGHHELI_03538 4e-116 yuiC S protein conserved in bacteria
DFGHHELI_03539 1.2e-77 yuiD S protein conserved in bacteria
DFGHHELI_03540 7.6e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DFGHHELI_03541 3.9e-211 yuiF S antiporter
DFGHHELI_03542 1.1e-93 bioY S Biotin biosynthesis protein
DFGHHELI_03543 2.9e-121 yuiH S Oxidoreductase molybdopterin binding domain
DFGHHELI_03544 1.9e-166 besA S Putative esterase
DFGHHELI_03545 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DFGHHELI_03546 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
DFGHHELI_03547 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
DFGHHELI_03548 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
DFGHHELI_03549 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_03550 3.8e-36 mbtH S MbtH-like protein
DFGHHELI_03551 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
DFGHHELI_03552 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
DFGHHELI_03553 1.9e-228 yukF QT Transcriptional regulator
DFGHHELI_03554 2.8e-45 esxA S Belongs to the WXG100 family
DFGHHELI_03555 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
DFGHHELI_03556 1.5e-210 essB S WXG100 protein secretion system (Wss), protein YukC
DFGHHELI_03557 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
DFGHHELI_03558 0.0 esaA S type VII secretion protein EsaA
DFGHHELI_03559 3.3e-64 yueC S Family of unknown function (DUF5383)
DFGHHELI_03560 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_03561 4.8e-96 yueE S phosphohydrolase
DFGHHELI_03562 2.9e-24 S Protein of unknown function (DUF2642)
DFGHHELI_03563 1e-17 S Protein of unknown function (DUF2283)
DFGHHELI_03564 5.4e-190 yueF S transporter activity
DFGHHELI_03565 6.6e-31 yueG S Spore germination protein gerPA/gerPF
DFGHHELI_03566 7.4e-39 yueH S YueH-like protein
DFGHHELI_03567 2.5e-65 yueI S Protein of unknown function (DUF1694)
DFGHHELI_03568 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
DFGHHELI_03569 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DFGHHELI_03570 3.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
DFGHHELI_03571 1.1e-22 yuzC
DFGHHELI_03573 1e-147 comQ H Polyprenyl synthetase
DFGHHELI_03575 0.0 comP 2.7.13.3 T Histidine kinase
DFGHHELI_03576 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DFGHHELI_03577 6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
DFGHHELI_03578 2.8e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
DFGHHELI_03579 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DFGHHELI_03580 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DFGHHELI_03581 2.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DFGHHELI_03582 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DFGHHELI_03583 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DFGHHELI_03584 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DFGHHELI_03585 5e-15
DFGHHELI_03586 8.2e-233 maeN C COG3493 Na citrate symporter
DFGHHELI_03587 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
DFGHHELI_03588 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
DFGHHELI_03589 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
DFGHHELI_03590 9.9e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
DFGHHELI_03591 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
DFGHHELI_03592 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DFGHHELI_03593 6.3e-78 yufK S Family of unknown function (DUF5366)
DFGHHELI_03594 5.3e-74 yuxK S protein conserved in bacteria
DFGHHELI_03595 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
DFGHHELI_03596 2.1e-183 yuxJ EGP Major facilitator Superfamily
DFGHHELI_03598 4.2e-115 kapD L the KinA pathway to sporulation
DFGHHELI_03599 3.3e-70 kapB G Kinase associated protein B
DFGHHELI_03600 9.6e-231 T PhoQ Sensor
DFGHHELI_03601 2.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DFGHHELI_03602 1.1e-40 yugE S Domain of unknown function (DUF1871)
DFGHHELI_03603 3.2e-155 yugF I Hydrolase
DFGHHELI_03604 1.6e-85 alaR K Transcriptional regulator
DFGHHELI_03605 2.1e-199 yugH 2.6.1.1 E Aminotransferase
DFGHHELI_03606 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
DFGHHELI_03607 4e-34 yuzA S Domain of unknown function (DUF378)
DFGHHELI_03608 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
DFGHHELI_03609 5.3e-228 yugK C Dehydrogenase
DFGHHELI_03610 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
DFGHHELI_03612 6.3e-72 yugN S YugN-like family
DFGHHELI_03613 1.1e-181 yugO P COG1226 Kef-type K transport systems
DFGHHELI_03614 5.4e-53 mstX S Membrane-integrating protein Mistic
DFGHHELI_03615 2.3e-38
DFGHHELI_03616 4.1e-116 yugP S Zn-dependent protease
DFGHHELI_03617 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
DFGHHELI_03618 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
DFGHHELI_03619 3.1e-71 yugU S Uncharacterised protein family UPF0047
DFGHHELI_03620 1e-35
DFGHHELI_03621 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
DFGHHELI_03622 7.9e-224 mcpA NT chemotaxis protein
DFGHHELI_03623 1.1e-220 mcpA NT chemotaxis protein
DFGHHELI_03624 5.5e-294 mcpA NT chemotaxis protein
DFGHHELI_03625 1.6e-237 mcpA NT chemotaxis protein
DFGHHELI_03626 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
DFGHHELI_03627 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
DFGHHELI_03628 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DFGHHELI_03629 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
DFGHHELI_03630 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
DFGHHELI_03631 3.3e-183 ygjR S Oxidoreductase
DFGHHELI_03632 3.7e-189 yubA S transporter activity
DFGHHELI_03633 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DFGHHELI_03635 6.2e-72 L Phage integrase family
DFGHHELI_03637 6.2e-11 K Helix-turn-helix domain
DFGHHELI_03638 6.6e-56
DFGHHELI_03644 8.8e-44
DFGHHELI_03645 1e-227
DFGHHELI_03649 9.8e-52
DFGHHELI_03650 8.8e-70
DFGHHELI_03651 4.8e-29
DFGHHELI_03653 6.2e-14 S Helix-turn-helix of insertion element transposase
DFGHHELI_03654 2.2e-75 tnpR1 L Resolvase, N terminal domain
DFGHHELI_03655 2.8e-147 S TIGRFAM Phage
DFGHHELI_03656 8.3e-124 S Phage portal protein, SPP1 Gp6-like
DFGHHELI_03657 1.5e-29 S Domain of unknown function (DUF4355)
DFGHHELI_03658 4e-95 S Phage capsid family
DFGHHELI_03660 1.3e-19 S Phage gp6-like head-tail connector protein
DFGHHELI_03662 0.0 S peptidoglycan catabolic process
DFGHHELI_03663 4.4e-275 S Pfam Transposase IS66
DFGHHELI_03664 4.5e-12
DFGHHELI_03665 4.4e-32 S Domain of unknown function (DUF4917)
DFGHHELI_03666 9.4e-28 S Protein of unknown function (DUF1433)
DFGHHELI_03667 5.2e-49 S Protein of unknown function (DUF1433)
DFGHHELI_03668 1.2e-181 I Pfam Lipase (class 3)
DFGHHELI_03669 1.2e-42 I Pfam Lipase (class 3)
DFGHHELI_03670 2.6e-41
DFGHHELI_03672 1.1e-08
DFGHHELI_03675 2.7e-09 K Transcriptional regulator
DFGHHELI_03680 1.4e-167 L Belongs to the 'phage' integrase family
DFGHHELI_03681 1.4e-49 xkdA E IrrE N-terminal-like domain
DFGHHELI_03684 1.8e-16 xre K Helix-turn-helix XRE-family like proteins
DFGHHELI_03685 6.4e-13 K Helix-turn-helix domain
DFGHHELI_03686 5.8e-15 S Helix-turn-helix domain
DFGHHELI_03687 1.2e-44 S DNA binding
DFGHHELI_03688 9.5e-82
DFGHHELI_03693 1.5e-97
DFGHHELI_03694 3e-65 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
DFGHHELI_03696 3.3e-76 L DnaD domain protein
DFGHHELI_03697 2e-80 xkdC L IstB-like ATP binding protein
DFGHHELI_03699 1.1e-11 S YopX protein
DFGHHELI_03701 6.8e-54 S Protein of unknown function (DUF1064)
DFGHHELI_03703 2.3e-25 yqaO S Phage-like element PBSX protein XtrA
DFGHHELI_03706 9e-104 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DFGHHELI_03709 1.5e-46 S dUTPase
DFGHHELI_03716 9.4e-80 L Transposase
DFGHHELI_03718 4.4e-71 yqaS L DNA packaging
DFGHHELI_03719 5.1e-202 S Terminase RNAseH like domain
DFGHHELI_03720 5.6e-169 S portal protein
DFGHHELI_03721 1.5e-94 M Phage minor capsid protein 2
DFGHHELI_03722 3.8e-15
DFGHHELI_03723 1.3e-98
DFGHHELI_03724 1.8e-10 G CBD_II
DFGHHELI_03725 1.1e-20
DFGHHELI_03726 2.7e-23 S Minor capsid protein
DFGHHELI_03727 4.4e-21 S Minor capsid protein
DFGHHELI_03728 7.5e-20 S Minor capsid protein from bacteriophage
DFGHHELI_03729 1.9e-40 N Belongs to the glycosyl hydrolase family 6
DFGHHELI_03730 4.2e-17
DFGHHELI_03731 4.1e-36 S Bacteriophage Gp15 protein
DFGHHELI_03732 1.9e-98 D minor tail protein
DFGHHELI_03733 3.2e-34 S Phage tail protein
DFGHHELI_03734 1.3e-183 sidC L Phage minor structural protein
DFGHHELI_03739 1.1e-27 xhlA S Haemolysin XhlA
DFGHHELI_03740 1.2e-31 xhlB S SPP1 phage holin
DFGHHELI_03741 3.4e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
DFGHHELI_03742 5.8e-31 KLT serine threonine protein kinase
DFGHHELI_03745 7.1e-28 K Helix-turn-helix domain
DFGHHELI_03746 1.1e-18
DFGHHELI_03747 4.2e-45 S YolD-like protein
DFGHHELI_03748 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
DFGHHELI_03749 1.9e-273 yubD P Major Facilitator Superfamily
DFGHHELI_03750 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DFGHHELI_03751 1e-38 yiaA S yiaA/B two helix domain
DFGHHELI_03752 2.7e-236 ktrB P Potassium
DFGHHELI_03753 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
DFGHHELI_03754 2.2e-91 yuaB
DFGHHELI_03755 3.6e-94 yuaC K Belongs to the GbsR family
DFGHHELI_03756 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
DFGHHELI_03757 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
DFGHHELI_03758 3.9e-107 yuaD
DFGHHELI_03759 3.9e-84 yuaE S DinB superfamily
DFGHHELI_03760 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
DFGHHELI_03761 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
DFGHHELI_03762 1.9e-92 M1-753 M FR47-like protein
DFGHHELI_03763 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
DFGHHELI_03764 2.5e-166 ygxA S Nucleotidyltransferase-like
DFGHHELI_03765 9.5e-56 ygzB S UPF0295 protein
DFGHHELI_03766 4e-80 perR P Belongs to the Fur family
DFGHHELI_03767 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
DFGHHELI_03768 3.4e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
DFGHHELI_03769 3.3e-179 ygaE S Membrane
DFGHHELI_03770 1.8e-301 ygaD V ABC transporter
DFGHHELI_03771 1.3e-104 ygaC J Belongs to the UPF0374 family
DFGHHELI_03772 1.5e-37 ygaB S YgaB-like protein
DFGHHELI_03773 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
DFGHHELI_03774 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DFGHHELI_03775 6.9e-36 yfhS
DFGHHELI_03776 3.3e-210 mutY L A G-specific
DFGHHELI_03777 1.2e-185 yfhP S membrane-bound metal-dependent
DFGHHELI_03778 0.0 yfhO S Bacterial membrane protein YfhO
DFGHHELI_03779 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
DFGHHELI_03780 3.7e-170 yfhM S Alpha beta hydrolase
DFGHHELI_03781 3.9e-50 yfhL S SdpI/YhfL protein family
DFGHHELI_03782 7.8e-91 batE T Bacterial SH3 domain homologues
DFGHHELI_03783 1.3e-44 yfhJ S WVELL protein
DFGHHELI_03784 6.2e-20 sspK S reproduction
DFGHHELI_03785 3.6e-208 yfhI EGP Major facilitator Superfamily
DFGHHELI_03786 1.7e-51 yfhH S Protein of unknown function (DUF1811)
DFGHHELI_03787 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
DFGHHELI_03788 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
DFGHHELI_03790 2.1e-25 yfhD S YfhD-like protein
DFGHHELI_03791 3.9e-107 yfhC C nitroreductase
DFGHHELI_03792 3.3e-166 yfhB 5.3.3.17 S PhzF family
DFGHHELI_03793 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03794 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03795 1.9e-175 yfiY P ABC transporter substrate-binding protein
DFGHHELI_03796 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DFGHHELI_03797 4.9e-79 yfiV K transcriptional
DFGHHELI_03798 1.9e-281 yfiU EGP Major facilitator Superfamily
DFGHHELI_03799 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
DFGHHELI_03800 2.1e-194 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DFGHHELI_03801 1e-34 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
DFGHHELI_03802 7.1e-40 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
DFGHHELI_03803 8.3e-99 padR K transcriptional
DFGHHELI_03804 1.4e-204 V COG0842 ABC-type multidrug transport system, permease component
DFGHHELI_03805 8.1e-208 V ABC-2 family transporter protein
DFGHHELI_03806 2.4e-167 V ABC transporter, ATP-binding protein
DFGHHELI_03807 5.4e-113 KT LuxR family transcriptional regulator
DFGHHELI_03808 6.8e-212 yxjM T Histidine kinase
DFGHHELI_03810 5.7e-163 yfiE 1.13.11.2 S glyoxalase
DFGHHELI_03811 9.8e-65 mhqP S DoxX
DFGHHELI_03812 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
DFGHHELI_03813 7.1e-306 yfiB3 V ABC transporter
DFGHHELI_03814 0.0 yobO M COG5434 Endopolygalacturonase
DFGHHELI_03815 8.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_03816 7.1e-141 glvR K Helix-turn-helix domain, rpiR family
DFGHHELI_03817 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DFGHHELI_03818 2.6e-44 yfjA S Belongs to the WXG100 family
DFGHHELI_03819 7.3e-172 yfjB
DFGHHELI_03820 4.7e-124 yfjC
DFGHHELI_03821 1.1e-85 S Family of unknown function (DUF5381)
DFGHHELI_03822 4e-56 yfjF S UPF0060 membrane protein
DFGHHELI_03823 1.2e-25 sspH S Belongs to the SspH family
DFGHHELI_03824 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
DFGHHELI_03825 2.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DFGHHELI_03826 1.5e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DFGHHELI_03827 5.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DFGHHELI_03828 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DFGHHELI_03829 1.3e-29 yfjL
DFGHHELI_03830 9.6e-85 yfjM S Psort location Cytoplasmic, score
DFGHHELI_03831 8.1e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DFGHHELI_03832 5.7e-43 S YfzA-like protein
DFGHHELI_03833 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DFGHHELI_03834 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DFGHHELI_03835 1.7e-184 corA P Mediates influx of magnesium ions
DFGHHELI_03836 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
DFGHHELI_03837 1.7e-153 pdaA G deacetylase
DFGHHELI_03838 1.1e-26 yfjT
DFGHHELI_03839 5.4e-222 yfkA S YfkB-like domain
DFGHHELI_03840 6e-149 yfkC M Mechanosensitive ion channel
DFGHHELI_03841 1.2e-146 yfkD S YfkD-like protein
DFGHHELI_03842 6.1e-183 cax P COG0387 Ca2 H antiporter
DFGHHELI_03843 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
DFGHHELI_03845 9.7e-144 yihY S Belongs to the UPF0761 family
DFGHHELI_03846 8.4e-51 yfkI S gas vesicle protein
DFGHHELI_03847 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DFGHHELI_03848 1.3e-28 yfkK S Belongs to the UPF0435 family
DFGHHELI_03849 6.8e-207 ydiM EGP Major facilitator Superfamily
DFGHHELI_03850 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
DFGHHELI_03851 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DFGHHELI_03852 1.1e-124 yfkO C nitroreductase
DFGHHELI_03853 1.8e-133 treR K transcriptional
DFGHHELI_03854 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DFGHHELI_03855 1.9e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DFGHHELI_03856 4e-27 yfkQ EG Spore germination protein
DFGHHELI_03857 6.3e-252 agcS_1 E Sodium alanine symporter
DFGHHELI_03858 6e-67 yhdN S Domain of unknown function (DUF1992)
DFGHHELI_03859 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DFGHHELI_03860 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
DFGHHELI_03861 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
DFGHHELI_03862 5.3e-50 yflH S Protein of unknown function (DUF3243)
DFGHHELI_03863 4.1e-19 yflI
DFGHHELI_03864 1.2e-17 yflJ S Protein of unknown function (DUF2639)
DFGHHELI_03865 4.2e-121 yflK S protein conserved in bacteria
DFGHHELI_03866 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DFGHHELI_03867 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DFGHHELI_03868 2.1e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
DFGHHELI_03869 1.9e-226 citM C Citrate transporter
DFGHHELI_03870 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
DFGHHELI_03871 2.6e-118 citT T response regulator
DFGHHELI_03872 4.8e-280 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
DFGHHELI_03873 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
DFGHHELI_03874 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
DFGHHELI_03875 7.6e-58 yflT S Heat induced stress protein YflT
DFGHHELI_03876 2.9e-24 S Protein of unknown function (DUF3212)
DFGHHELI_03877 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
DFGHHELI_03878 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03879 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DFGHHELI_03880 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
DFGHHELI_03881 2.5e-189 yfmJ S N-terminal domain of oxidoreductase
DFGHHELI_03882 2.7e-76 yfmK 2.3.1.128 K acetyltransferase
DFGHHELI_03883 7.7e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
DFGHHELI_03884 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DFGHHELI_03885 2.5e-36
DFGHHELI_03886 1.2e-208 yfmO EGP Major facilitator Superfamily
DFGHHELI_03887 2.4e-69 yfmP K transcriptional
DFGHHELI_03888 1.2e-68 yfmQ S Uncharacterised protein from bacillus cereus group
DFGHHELI_03889 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DFGHHELI_03890 1.1e-113 yfmS NT chemotaxis protein
DFGHHELI_03891 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DFGHHELI_03892 1.1e-240 yfnA E amino acid
DFGHHELI_03893 4.3e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DFGHHELI_03894 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
DFGHHELI_03895 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
DFGHHELI_03896 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
DFGHHELI_03897 5.1e-178 yfnF M Nucleotide-diphospho-sugar transferase
DFGHHELI_03898 3.2e-172 yfnG 4.2.1.45 M dehydratase
DFGHHELI_03899 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
DFGHHELI_03900 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DFGHHELI_03901 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
DFGHHELI_03902 1.4e-195 yetN S Protein of unknown function (DUF3900)
DFGHHELI_03903 3.3e-134 M Membrane
DFGHHELI_03904 2.2e-207 yetM CH FAD binding domain
DFGHHELI_03905 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
DFGHHELI_03906 5.3e-105 yetJ S Belongs to the BI1 family
DFGHHELI_03907 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
DFGHHELI_03908 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DFGHHELI_03909 2.4e-34
DFGHHELI_03910 4.8e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGHHELI_03911 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
DFGHHELI_03912 5.7e-121 yetF S membrane
DFGHHELI_03913 7.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
DFGHHELI_03914 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
DFGHHELI_03915 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
DFGHHELI_03916 4e-289 lplA G Bacterial extracellular solute-binding protein
DFGHHELI_03917 0.0 yetA
DFGHHELI_03918 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
DFGHHELI_03919 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
DFGHHELI_03920 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
DFGHHELI_03921 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
DFGHHELI_03922 9.7e-112 yesV S Protein of unknown function, DUF624
DFGHHELI_03923 2.5e-126 yesU S Domain of unknown function (DUF1961)
DFGHHELI_03924 2.5e-132 E GDSL-like Lipase/Acylhydrolase
DFGHHELI_03925 0.0 yesS K Transcriptional regulator
DFGHHELI_03926 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
DFGHHELI_03927 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
DFGHHELI_03928 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
DFGHHELI_03929 2.1e-246 yesO G Bacterial extracellular solute-binding protein
DFGHHELI_03930 1.8e-198 yesN K helix_turn_helix, arabinose operon control protein
DFGHHELI_03931 0.0 yesM 2.7.13.3 T Histidine kinase
DFGHHELI_03932 8.5e-100 yesL S Protein of unknown function, DUF624
DFGHHELI_03934 6e-102 yesJ K Acetyltransferase (GNAT) family
DFGHHELI_03935 5.2e-104 cotJC P Spore Coat
DFGHHELI_03936 1.5e-45 cotJB S CotJB protein
DFGHHELI_03937 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
DFGHHELI_03938 4.5e-144 yesF GM NAD(P)H-binding
DFGHHELI_03939 2.2e-81 yesE S SnoaL-like domain
DFGHHELI_03940 8.8e-99 dhaR3 K Transcriptional regulator
DFGHHELI_03942 9.4e-127 yeeN K transcriptional regulatory protein
DFGHHELI_03944 7.9e-213 S Tetratricopeptide repeat
DFGHHELI_03945 6.7e-39
DFGHHELI_03946 2.4e-176 3.4.24.40 CO amine dehydrogenase activity
DFGHHELI_03947 0.0 L nucleic acid phosphodiester bond hydrolysis
DFGHHELI_03948 5.5e-83 S Protein of unknown function, DUF600
DFGHHELI_03949 7.1e-32
DFGHHELI_03950 6.4e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DFGHHELI_03951 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DFGHHELI_03952 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DFGHHELI_03953 1.3e-148 yerO K Transcriptional regulator
DFGHHELI_03954 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFGHHELI_03955 7.9e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DFGHHELI_03956 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFGHHELI_03957 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFGHHELI_03958 1.6e-123 sapB S MgtC SapB transporter
DFGHHELI_03959 1e-195 yerI S homoserine kinase type II (protein kinase fold)
DFGHHELI_03960 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
DFGHHELI_03961 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DFGHHELI_03962 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DFGHHELI_03963 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DFGHHELI_03965 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
DFGHHELI_03966 4.8e-51 yerC S protein conserved in bacteria
DFGHHELI_03967 3.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
DFGHHELI_03968 0.0 yerA 3.5.4.2 F adenine deaminase
DFGHHELI_03969 1.6e-27 S Protein of unknown function (DUF2892)
DFGHHELI_03970 6.1e-230 yjeH E Amino acid permease
DFGHHELI_03971 1e-72 K helix_turn_helix ASNC type
DFGHHELI_03972 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
DFGHHELI_03973 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DFGHHELI_03974 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DFGHHELI_03975 8.4e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DFGHHELI_03976 1.4e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DFGHHELI_03977 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DFGHHELI_03978 2.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DFGHHELI_03979 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DFGHHELI_03980 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DFGHHELI_03981 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DFGHHELI_03982 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DFGHHELI_03983 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DFGHHELI_03984 8e-28 yebG S NETI protein
DFGHHELI_03985 8.9e-93 yebE S UPF0316 protein
DFGHHELI_03987 2.3e-118 yebC M Membrane
DFGHHELI_03988 1e-211 pbuG S permease
DFGHHELI_03989 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DFGHHELI_03990 0.0 yebA E COG1305 Transglutaminase-like enzymes
DFGHHELI_03991 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
DFGHHELI_03992 2.7e-177 yeaC S COG0714 MoxR-like ATPases
DFGHHELI_03993 1.9e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DFGHHELI_03994 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
DFGHHELI_03995 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
DFGHHELI_03996 6.1e-177 yeaA S Protein of unknown function (DUF4003)
DFGHHELI_03997 4.4e-157 ydjP I Alpha/beta hydrolase family
DFGHHELI_03998 1.4e-34 ydjO S Cold-inducible protein YdjO
DFGHHELI_04000 1.7e-153 ydjN U Involved in the tonB-independent uptake of proteins
DFGHHELI_04001 1.3e-63 ydjM M Lytic transglycolase
DFGHHELI_04002 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
DFGHHELI_04003 2.5e-256 iolT EGP Major facilitator Superfamily
DFGHHELI_04004 6.7e-195 S Ion transport 2 domain protein
DFGHHELI_04005 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
DFGHHELI_04006 4.3e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
DFGHHELI_04007 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DFGHHELI_04008 8.7e-114 pspA KT Phage shock protein A
DFGHHELI_04009 1.6e-174 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
DFGHHELI_04010 2.1e-252 gutA G MFS/sugar transport protein
DFGHHELI_04011 4.2e-200 gutB 1.1.1.14 E Dehydrogenase
DFGHHELI_04012 0.0 K NB-ARC domain
DFGHHELI_04013 3.3e-57
DFGHHELI_04015 4.8e-233 M peptidoglycan-binding domain-containing protein
DFGHHELI_04016 2.8e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DFGHHELI_04017 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DFGHHELI_04018 7.9e-129 ydiL S CAAX protease self-immunity
DFGHHELI_04019 2.9e-27 ydiK S Domain of unknown function (DUF4305)
DFGHHELI_04020 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DFGHHELI_04021 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DFGHHELI_04022 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DFGHHELI_04023 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
DFGHHELI_04024 0.0 ydiF S ABC transporter
DFGHHELI_04025 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DFGHHELI_04026 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DFGHHELI_04027 1.1e-121 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
DFGHHELI_04028 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
DFGHHELI_04029 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DFGHHELI_04031 7.8e-08
DFGHHELI_04032 2.6e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
DFGHHELI_04033 3.4e-08
DFGHHELI_04034 9.8e-36 O Glutaredoxin
DFGHHELI_04035 1.7e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGHHELI_04037 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGHHELI_04038 1.6e-26 S NrdI Flavodoxin like
DFGHHELI_04043 1.5e-11 S YopX protein
DFGHHELI_04050 9.3e-26 S hydrolase activity
DFGHHELI_04056 2.4e-63 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DFGHHELI_04059 2.5e-78 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
DFGHHELI_04062 5.7e-23 S protein conserved in bacteria
DFGHHELI_04063 2.6e-292 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
DFGHHELI_04064 1.5e-168 S PD-(D/E)XK nuclease superfamily
DFGHHELI_04065 3.5e-151 3.6.4.12 L DNA primase activity
DFGHHELI_04066 3.4e-240 3.6.4.12 L DnaB-like helicase C terminal domain
DFGHHELI_04068 3.1e-145 S AAA domain
DFGHHELI_04069 1.5e-169
DFGHHELI_04071 5.9e-08 S response to antibiotic
DFGHHELI_04073 1.5e-84 K SIR2-like domain
DFGHHELI_04075 1.4e-127 yoqW S Belongs to the SOS response-associated peptidase family
DFGHHELI_04076 3.5e-146 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
DFGHHELI_04084 1.2e-06 V endonuclease activity
DFGHHELI_04085 1.5e-94 S Protein of unknown function (DUF1273)
DFGHHELI_04088 2.8e-68 yoqH M LysM domain
DFGHHELI_04092 1.4e-06 K AntA/AntB antirepressor
DFGHHELI_04096 6.9e-32
DFGHHELI_04097 1.9e-245
DFGHHELI_04098 2.2e-39 L Belongs to the 'phage' integrase family
DFGHHELI_04104 7.8e-83
DFGHHELI_04106 5.8e-32 yoaF
DFGHHELI_04107 8.4e-74 S SEFIR domain
DFGHHELI_04112 1.1e-09 ywlA S Uncharacterised protein family (UPF0715)
DFGHHELI_04116 2.6e-30 K Cro/C1-type HTH DNA-binding domain
DFGHHELI_04117 6.2e-81 yoaW
DFGHHELI_04118 3.2e-08 S Uncharacterised protein family (UPF0715)
DFGHHELI_04119 5.2e-36 S Putative zinc- or iron-chelating domain
DFGHHELI_04121 1.9e-18
DFGHHELI_04123 7.9e-12
DFGHHELI_04126 2e-230 S DNA replication origin binding
DFGHHELI_04128 3e-47
DFGHHELI_04131 0.0
DFGHHELI_04132 3.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DFGHHELI_04135 8.3e-205 S Calcineurin-like phosphoesterase superfamily domain
DFGHHELI_04138 1.8e-175
DFGHHELI_04139 0.0 gp17a S Terminase-like family
DFGHHELI_04140 9.4e-278
DFGHHELI_04141 2e-253
DFGHHELI_04142 7.8e-94
DFGHHELI_04143 1.3e-185
DFGHHELI_04144 7.4e-80
DFGHHELI_04145 7.9e-67
DFGHHELI_04147 7e-121
DFGHHELI_04148 8.8e-79
DFGHHELI_04149 1.5e-71
DFGHHELI_04150 3.2e-59
DFGHHELI_04153 3.8e-52
DFGHHELI_04154 6.3e-30
DFGHHELI_04157 6.5e-55
DFGHHELI_04158 3.3e-63
DFGHHELI_04159 4e-123 xerH L Belongs to the 'phage' integrase family
DFGHHELI_04163 1.1e-108
DFGHHELI_04164 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DFGHHELI_04165 1.6e-87 S Phage tail protein
DFGHHELI_04166 1.5e-302 S Pfam Transposase IS66
DFGHHELI_04167 9.5e-99
DFGHHELI_04168 6e-55 S outer membrane
DFGHHELI_04169 4.3e-179 S N-acetylmuramoyl-L-alanine amidase activity
DFGHHELI_04171 4.1e-37 S Bacteriophage holin
DFGHHELI_04172 4.4e-102 S response regulator aspartate phosphatase
DFGHHELI_04174 3.7e-43 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
DFGHHELI_04175 4.8e-21 Q Methyltransferase
DFGHHELI_04176 4.6e-35 2.7.7.73, 2.7.7.80 H ThiF family
DFGHHELI_04177 2e-32 Q Methyltransferase domain
DFGHHELI_04178 8.2e-22 G Major Facilitator Superfamily
DFGHHELI_04179 1.8e-234 S impB/mucB/samB family C-terminal domain
DFGHHELI_04180 4.6e-52 S YolD-like protein
DFGHHELI_04181 1.4e-39
DFGHHELI_04183 4e-09 S Domain of unknown function (DUF4879)
DFGHHELI_04185 1e-93 J Acetyltransferase (GNAT) domain
DFGHHELI_04186 4.2e-93 yokK S SMI1 / KNR4 family
DFGHHELI_04187 8.8e-78 S SMI1-KNR4 cell-wall
DFGHHELI_04188 3.5e-173 yobL S Bacterial EndoU nuclease
DFGHHELI_04189 1.6e-61 G SMI1-KNR4 cell-wall
DFGHHELI_04190 7.2e-15
DFGHHELI_04191 1.6e-107 yokF 3.1.31.1 L RNA catabolic process
DFGHHELI_04192 2.2e-79 S Bacterial PH domain
DFGHHELI_04193 1.3e-56 S DNase/tRNase domain of colicin-like bacteriocin
DFGHHELI_04194 5.5e-70 S SMI1 / KNR4 family
DFGHHELI_04196 7.6e-241 yokA L Recombinase
DFGHHELI_04198 1.4e-88 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DFGHHELI_04199 2.4e-10 K Cro/C1-type HTH DNA-binding domain
DFGHHELI_04209 1.5e-34
DFGHHELI_04211 6.7e-161 S Calcineurin-like phosphoesterase
DFGHHELI_04212 4.7e-29 sspB S spore protein
DFGHHELI_04215 1.5e-60
DFGHHELI_04217 2.9e-159 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DFGHHELI_04220 4e-15
DFGHHELI_04221 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
DFGHHELI_04222 3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
DFGHHELI_04223 1.2e-84 gerD
DFGHHELI_04224 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DFGHHELI_04225 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
DFGHHELI_04226 1.8e-64 ybaK S Protein of unknown function (DUF2521)
DFGHHELI_04227 7.6e-143 ybaJ Q Methyltransferase domain
DFGHHELI_04228 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
DFGHHELI_04229 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DFGHHELI_04230 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DFGHHELI_04231 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DFGHHELI_04232 6.4e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DFGHHELI_04233 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DFGHHELI_04234 3.6e-58 rplQ J Ribosomal protein L17
DFGHHELI_04235 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGHHELI_04236 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DFGHHELI_04237 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFGHHELI_04238 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DFGHHELI_04239 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DFGHHELI_04240 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
DFGHHELI_04241 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DFGHHELI_04242 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DFGHHELI_04243 1.8e-72 rplO J binds to the 23S rRNA
DFGHHELI_04244 1.9e-23 rpmD J Ribosomal protein L30
DFGHHELI_04245 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DFGHHELI_04246 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DFGHHELI_04247 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DFGHHELI_04248 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DFGHHELI_04249 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DFGHHELI_04250 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DFGHHELI_04251 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DFGHHELI_04252 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DFGHHELI_04253 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DFGHHELI_04254 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
DFGHHELI_04255 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DFGHHELI_04256 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DFGHHELI_04257 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DFGHHELI_04258 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DFGHHELI_04259 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DFGHHELI_04260 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DFGHHELI_04261 3e-105 rplD J Forms part of the polypeptide exit tunnel
DFGHHELI_04262 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DFGHHELI_04263 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DFGHHELI_04264 6.5e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
DFGHHELI_04265 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DFGHHELI_04266 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DFGHHELI_04267 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DFGHHELI_04268 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DFGHHELI_04269 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
DFGHHELI_04270 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGHHELI_04271 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGHHELI_04272 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
DFGHHELI_04273 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DFGHHELI_04274 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DFGHHELI_04275 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DFGHHELI_04276 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DFGHHELI_04277 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
DFGHHELI_04278 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DFGHHELI_04279 4.4e-115 sigH K Belongs to the sigma-70 factor family
DFGHHELI_04280 1.2e-88 yacP S RNA-binding protein containing a PIN domain
DFGHHELI_04281 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFGHHELI_04282 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DFGHHELI_04283 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGHHELI_04284 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
DFGHHELI_04285 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DFGHHELI_04286 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DFGHHELI_04287 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DFGHHELI_04288 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
DFGHHELI_04289 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DFGHHELI_04290 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DFGHHELI_04291 0.0 clpC O Belongs to the ClpA ClpB family
DFGHHELI_04292 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
DFGHHELI_04293 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
DFGHHELI_04294 2.9e-76 ctsR K Belongs to the CtsR family
DFGHHELI_04295 3.4e-31 csfB S Inhibitor of sigma-G Gin
DFGHHELI_04296 8.9e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
DFGHHELI_04297 1.6e-200 yaaN P Belongs to the TelA family
DFGHHELI_04298 3.9e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
DFGHHELI_04299 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DFGHHELI_04300 2.2e-54 yaaQ S protein conserved in bacteria
DFGHHELI_04301 1.5e-71 yaaR S protein conserved in bacteria
DFGHHELI_04302 2.2e-182 holB 2.7.7.7 L DNA polymerase III
DFGHHELI_04303 6.1e-146 yaaT S stage 0 sporulation protein
DFGHHELI_04304 4.8e-31 yabA L Involved in initiation control of chromosome replication
DFGHHELI_04305 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
DFGHHELI_04306 1.5e-49 yazA L endonuclease containing a URI domain
DFGHHELI_04307 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DFGHHELI_04308 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
DFGHHELI_04309 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DFGHHELI_04310 1.2e-143 tatD L hydrolase, TatD
DFGHHELI_04311 4.3e-194 rpfB GH23 T protein conserved in bacteria
DFGHHELI_04312 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DFGHHELI_04313 1.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DFGHHELI_04314 1.6e-136 yabG S peptidase
DFGHHELI_04315 7.8e-39 veg S protein conserved in bacteria
DFGHHELI_04316 2.4e-26 sspF S DNA topological change
DFGHHELI_04317 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DFGHHELI_04318 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DFGHHELI_04319 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
DFGHHELI_04320 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
DFGHHELI_04321 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DFGHHELI_04322 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DFGHHELI_04323 8.7e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DFGHHELI_04324 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DFGHHELI_04325 2.4e-39 yabK S Peptide ABC transporter permease
DFGHHELI_04326 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DFGHHELI_04327 1.5e-92 spoVT K stage V sporulation protein
DFGHHELI_04328 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DFGHHELI_04329 2.3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
DFGHHELI_04330 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DFGHHELI_04331 1.5e-49 yabP S Sporulation protein YabP
DFGHHELI_04332 4.3e-107 yabQ S spore cortex biosynthesis protein
DFGHHELI_04333 1.1e-44 divIC D Septum formation initiator
DFGHHELI_04334 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
DFGHHELI_04337 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
DFGHHELI_04338 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
DFGHHELI_04339 2.8e-185 KLT serine threonine protein kinase
DFGHHELI_04340 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DFGHHELI_04341 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DFGHHELI_04342 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DFGHHELI_04343 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DFGHHELI_04344 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DFGHHELI_04345 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
DFGHHELI_04346 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DFGHHELI_04347 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DFGHHELI_04348 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
DFGHHELI_04349 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
DFGHHELI_04350 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DFGHHELI_04351 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DFGHHELI_04352 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DFGHHELI_04353 4.1e-30 yazB K transcriptional
DFGHHELI_04354 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DFGHHELI_04355 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DFGHHELI_04359 2e-08
DFGHHELI_04361 1.1e-09 lexA 3.4.21.88 K LexA DNA binding domain
DFGHHELI_04362 1.3e-08 K Transcriptional regulator
DFGHHELI_04363 1.4e-37 S YolD-like protein
DFGHHELI_04365 6.8e-156 S Aspartate phosphatase response regulator
DFGHHELI_04366 1.6e-172 A Pre-toxin TG
DFGHHELI_04367 7.4e-27
DFGHHELI_04368 2.6e-18
DFGHHELI_04369 3.2e-36
DFGHHELI_04370 1.1e-122 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
DFGHHELI_04371 2.7e-57 S Bacteriophage holin family
DFGHHELI_04372 1.5e-150 xepA
DFGHHELI_04373 1.1e-19
DFGHHELI_04374 1e-43 xkdW S XkdW protein
DFGHHELI_04375 5.6e-157
DFGHHELI_04376 1.7e-36
DFGHHELI_04377 1.3e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
DFGHHELI_04378 6.7e-182 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DFGHHELI_04379 3.8e-67 xkdS S Protein of unknown function (DUF2634)
DFGHHELI_04380 5.5e-32 xkdR S Protein of unknown function (DUF2577)
DFGHHELI_04381 2.3e-176 yqbQ 3.2.1.96 G NLP P60 protein
DFGHHELI_04382 2.7e-110 xkdP S Lysin motif
DFGHHELI_04383 0.0 xkdO L Transglycosylase SLT domain
DFGHHELI_04384 8.9e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
DFGHHELI_04386 7.4e-74 xkdM S Phage tail tube protein
DFGHHELI_04387 4.1e-243 xkdK S Phage tail sheath C-terminal domain
DFGHHELI_04388 3.1e-24
DFGHHELI_04389 9.6e-66
DFGHHELI_04390 1.8e-84 S Bacteriophage HK97-gp10, putative tail-component
DFGHHELI_04391 8.8e-57 yqbH S Domain of unknown function (DUF3599)
DFGHHELI_04392 2e-46 S Protein of unknown function (DUF3199)
DFGHHELI_04393 2.1e-25 S YqbF, hypothetical protein domain
DFGHHELI_04394 1.6e-147 xkdG S Phage capsid family
DFGHHELI_04395 1.4e-95 yqbD 2.1.1.72 L Putative phage serine protease XkdF
DFGHHELI_04397 1.8e-146 S Phage Mu protein F like protein
DFGHHELI_04398 5.8e-251 yqbA S portal protein
DFGHHELI_04399 7.2e-234 S phage terminase, large subunit
DFGHHELI_04400 1.3e-74
DFGHHELI_04401 2.2e-30
DFGHHELI_04402 1.9e-96
DFGHHELI_04403 1.5e-62 K DNA binding
DFGHHELI_04408 1.2e-39
DFGHHELI_04411 2e-38
DFGHHELI_04412 9.3e-24
DFGHHELI_04415 3.2e-30
DFGHHELI_04418 7.1e-63
DFGHHELI_04419 1.2e-58 rusA L Endodeoxyribonuclease RusA
DFGHHELI_04422 1.3e-179 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DFGHHELI_04423 2.9e-07 S Loader and inhibitor of phage G40P
DFGHHELI_04424 8.9e-27 L primosome component and related proteins
DFGHHELI_04426 5.4e-103 S Metallo-beta-lactamase superfamily
DFGHHELI_04427 5.9e-115 recT L RecT family
DFGHHELI_04429 5.7e-174 D nuclear chromosome segregation
DFGHHELI_04433 8.2e-43
DFGHHELI_04434 7.1e-13 S Helix-turn-helix domain
DFGHHELI_04435 8.3e-14 K Helix-turn-helix XRE-family like proteins
DFGHHELI_04436 8.5e-51 bldD K domain, Protein
DFGHHELI_04437 2.1e-24
DFGHHELI_04438 4.3e-36 xkdA E IrrE N-terminal-like domain
DFGHHELI_04439 4e-82 L Phage integrase, N-terminal SAM-like domain
DFGHHELI_04442 1.1e-180 yaaC S YaaC-like Protein
DFGHHELI_04443 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DFGHHELI_04444 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DFGHHELI_04445 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DFGHHELI_04446 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DFGHHELI_04447 6.9e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DFGHHELI_04448 1.3e-09
DFGHHELI_04449 2.7e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
DFGHHELI_04450 3.7e-111 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
DFGHHELI_04451 3.9e-208 yaaH M Glycoside Hydrolase Family
DFGHHELI_04452 8.8e-93 yaaI Q COG1335 Amidases related to nicotinamidase
DFGHHELI_04453 1.6e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DFGHHELI_04454 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DFGHHELI_04455 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DFGHHELI_04456 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DFGHHELI_04457 7.9e-32 yaaL S Protein of unknown function (DUF2508)
DFGHHELI_04458 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
DFGHHELI_04459 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_04460 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_04461 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DFGHHELI_04462 2.8e-177 L Replication protein
DFGHHELI_04464 5.5e-21 S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DFGHHELI_04465 3.3e-25 traI 2.5.1.15 U relaxase mobilization nuclease domain protein
DFGHHELI_04467 4.4e-64 K Transcriptional regulator
DFGHHELI_04470 2.4e-137 S COG0457 FOG TPR repeat
DFGHHELI_04471 3.4e-39 S COG NOG14552 non supervised orthologous group
DFGHHELI_04472 2e-08
DFGHHELI_04477 7.3e-46 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)